| GS | GS DESC | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | 1 | hsp27Pathway | Details ... | 15 | 0.78 | 2.18 | 0.000 | 0.003 | 0.004 |
2 | p53hypoxiaPathway | Details ... | 20 | 0.68 | 2.08 | 0.000 | 0.009 | 0.013 |
3 | p53Pathway | Details ... | 16 | 0.75 | 2.06 | 0.000 | 0.009 | 0.018 |
4 | P53_UP | Details ... | 40 | 0.60 | 1.88 | 0.000 | 0.065 | 0.195 |
5 | radiation_sensitivity | Details ... | 26 | 0.57 | 1.83 | 0.002 | 0.088 | 0.296 |
6 | ck1Pathway | Details ... | 15 | 0.54 | 1.63 | 0.015 | 0.449 | 0.835 |
7 | inflamPathway | Details ... | 28 | 0.54 | 1.55 | 0.049 | 0.701 | 0.955 |
8 | no2il12Pathway | Details ... | 17 | 0.63 | 1.52 | 0.049 | 0.776 | 0.975 |
9 | badPathway | Details ... | 21 | 0.47 | 1.51 | 0.056 | 0.710 | 0.977 |
10 | lairPathway | Details ... | 15 | 0.57 | 1.50 | 0.057 | 0.709 | 0.986 |
11 | chemicalPathway | Details ... | 21 | 0.46 | 1.49 | 0.045 | 0.692 | 0.989 |
12 | GPCRs_Class_A_Rhodopsin-like | Details ... | 111 | 0.43 | 1.47 | 0.062 | 0.692 | 0.991 |
13 | cytokinePathway | Details ... | 21 | 0.54 | 1.47 | 0.095 | 0.643 | 0.991 |
14 | p53_signalling | Details ... | 87 | 0.34 | 1.47 | 0.028 | 0.614 | 0.994 |
15 | MAP00561_Glycerolipid_metabolism | Details ... | 43 | 0.42 | 1.42 | 0.073 | 0.752 | 0.998 |
16 | ST_Interleukin_4_Pathway | Details ... | 24 | 0.40 | 1.34 | 0.100 | 1.000 | 1.000 |
17 | HTERT_DOWN | Details ... | 64 | 0.34 | 1.32 | 0.111 | 1.000 | 1.000 |
18 | MAP00195_Photosynthesis | Details ... | 16 | 0.56 | 1.31 | 0.229 | 1.000 | 1.000 |
19 | ST_Wnt_Ca2_cyclic_GMP_Pathway | Details ... | 19 | 0.45 | 1.29 | 0.165 | 1.000 | 1.000 |
20 | ca_nf_at_signalling | Details ... | 95 | 0.33 | 1.28 | 0.134 | 1.000 | 1.000 |
21 | nktPathway | | 27 | 0.43 | 1.28 | 0.189 | 1.000 | 1.000 |
22 | cell_adhesion_receptor_activity | | 29 | 0.40 | 1.27 | 0.147 | 1.000 | 1.000 |
23 | atmPathway | | 19 | 0.43 | 1.25 | 0.218 | 1.000 | 1.000 |
24 | no1Pathway | | 28 | 0.36 | 1.24 | 0.176 | 1.000 | 1.000 |
25 | GPCRs_Class_B_Secretin-like | | 22 | 0.42 | 1.24 | 0.195 | 1.000 | 1.000 |
26 | DNA_DAMAGE_SIGNALLING | | 90 | 0.32 | 1.24 | 0.223 | 1.000 | 1.000 |
27 | Inflammatory_Response_Pathway | | 27 | 0.43 | 1.23 | 0.215 | 1.000 | 1.000 |
28 | calcineurinPathway | | 18 | 0.41 | 1.23 | 0.221 | 1.000 | 1.000 |
29 | drug_resistance_and_metabolism | | 95 | 0.27 | 1.23 | 0.128 | 0.995 | 1.000 |
30 | MAP00193_ATP_synthesis | | 15 | 0.53 | 1.22 | 0.311 | 0.998 | 1.000 |
31 | MAP03070_Type_III_secretion_system | | 15 | 0.53 | 1.22 | 0.311 | 0.966 | 1.000 |
32 | dcPathway | | 19 | 0.46 | 1.21 | 0.255 | 0.969 | 1.000 |
33 | MAP00052_Galactose_metabolism | | 22 | 0.40 | 1.21 | 0.220 | 0.949 | 1.000 |
34 | th1th2Pathway | | 18 | 0.41 | 1.17 | 0.269 | 1.000 | 1.000 |
35 | stemPathway | | 15 | 0.47 | 1.16 | 0.305 | 1.000 | 1.000 |
36 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | | 26 | 0.34 | 1.14 | 0.298 | 1.000 | 1.000 |
37 | cell_cycle_regulator | | 23 | 0.39 | 1.13 | 0.331 | 1.000 | 1.000 |
38 | MAP00562_Inositol_phosphate_metabolism | | 18 | 0.37 | 1.13 | 0.310 | 1.000 | 1.000 |
39 | Eicosanoid_Synthesis | | 15 | 0.41 | 1.13 | 0.292 | 1.000 | 1.000 |
40 | MAP00230_Purine_metabolism | | 80 | 0.29 | 1.12 | 0.284 | 1.000 | 1.000 |
41 | CBF_LEUKEMIA_DOWNING_AML | | 56 | 0.32 | 1.12 | 0.297 | 1.000 | 1.000 |
42 | GNF_FEMALE_GENES | | 77 | 0.30 | 1.12 | 0.311 | 1.000 | 1.000 |
43 | ctlPathway | | 15 | 0.55 | 1.11 | 0.444 | 1.000 | 1.000 |
44 | crebPathway | | 25 | 0.34 | 1.11 | 0.319 | 1.000 | 1.000 |
45 | Il12Pathway | | 23 | 0.41 | 1.11 | 0.401 | 0.997 | 1.000 |
46 | mitochondriaPathway | | 19 | 0.37 | 1.09 | 0.355 | 1.000 | 1.000 |
47 | il1rPathway | | 29 | 0.32 | 1.08 | 0.339 | 1.000 | 1.000 |
48 | MAP00860_Porphyrin_and_chlorophyll_metabolism | | 17 | 0.41 | 1.08 | 0.363 | 1.000 | 1.000 |
49 | vipPathway | | 25 | 0.32 | 1.08 | 0.322 | 1.000 | 1.000 |
50 | GLYCOL | | 20 | 0.37 | 1.08 | 0.382 | 0.994 | 1.000 |
51 | MAP00020_Citrate_cycle_TCA_cycle | | 18 | 0.41 | 1.08 | 0.382 | 0.975 | 1.000 |
52 | ceramidePathway | | 22 | 0.32 | 1.07 | 0.370 | 0.987 | 1.000 |
53 | mprPathway | | 22 | 0.34 | 1.07 | 0.363 | 0.970 | 1.000 |
54 | intrinsicPathway | | 22 | 0.39 | 1.07 | 0.381 | 0.970 | 1.000 |
55 | MAP00500_Starch_and_sucrose_metabolism | | 20 | 0.37 | 1.06 | 0.389 | 0.954 | 1.000 |
56 | tidPathway | | 18 | 0.34 | 1.05 | 0.385 | 0.972 | 1.000 |
57 | MAP00120_Bile_acid_biosynthesis | | 21 | 0.37 | 1.05 | 0.398 | 0.961 | 1.000 |
58 | PROLIF_GENES | | 358 | 0.21 | 1.05 | 0.334 | 0.950 | 1.000 |
59 | CR_DEATH | | 70 | 0.27 | 1.05 | 0.391 | 0.938 | 1.000 |
60 | cell_adhesion_molecule_activity | | 95 | 0.26 | 1.04 | 0.392 | 0.948 | 1.000 |
61 | g1Pathway | | 26 | 0.31 | 1.04 | 0.386 | 0.943 | 1.000 |
62 | nthiPathway | | 21 | 0.34 | 1.03 | 0.410 | 0.950 | 1.000 |
63 | MAP00030_Pentose_phosphate_pathway | | 15 | 0.37 | 1.02 | 0.441 | 0.957 | 1.000 |
64 | chrebpPathway | | 17 | 0.35 | 1.02 | 0.425 | 0.955 | 1.000 |
65 | ucalpainPathway | | 16 | 0.39 | 1.02 | 0.439 | 0.944 | 1.000 |
66 | MAP00350_Tyrosine_metabolism | | 28 | 0.33 | 1.02 | 0.446 | 0.931 | 1.000 |
67 | g2Pathway | | 23 | 0.34 | 1.01 | 0.455 | 0.927 | 1.000 |
68 | bcl2family_and_reg_network | | 23 | 0.30 | 1.01 | 0.461 | 0.919 | 1.000 |
69 | GLUCO | | 31 | 0.30 | 1.00 | 0.441 | 0.917 | 1.000 |
70 | MAP00590_Prostaglandin_and_leukotriene_metabolism | | 17 | 0.36 | 1.00 | 0.438 | 0.907 | 1.000 |
71 | rarrxrPathway | | 15 | 0.36 | 0.99 | 0.474 | 0.936 | 1.000 |
72 | FA | | 21 | 0.33 | 0.98 | 0.497 | 0.956 | 1.000 |
73 | etsPathway | | 16 | 0.34 | 0.98 | 0.493 | 0.943 | 1.000 |
74 | cell_adhesion | | 167 | 0.25 | 0.98 | 0.479 | 0.931 | 1.000 |
75 | electron_transporter_activity | | 108 | 0.25 | 0.97 | 0.502 | 0.938 | 1.000 |
76 | S1P_Signaling | | 20 | 0.31 | 0.97 | 0.521 | 0.929 | 1.000 |
77 | amiPathway | | 22 | 0.40 | 0.96 | 0.533 | 0.928 | 1.000 |
78 | cskPathway | | 22 | 0.40 | 0.96 | 0.533 | 0.916 | 1.000 |
79 | il17Pathway | | 17 | 0.43 | 0.96 | 0.563 | 0.913 | 1.000 |
80 | Matrix_Metalloproteinases | | 22 | 0.34 | 0.96 | 0.528 | 0.906 | 1.000 |
81 | cell_surface_receptor_linked_signal_transduction | | 123 | 0.24 | 0.96 | 0.539 | 0.900 | 1.000 |
82 | il2rbPathway | | 36 | 0.29 | 0.95 | 0.543 | 0.894 | 1.000 |
83 | CR_IMMUNE_FUNCTION | | 50 | 0.28 | 0.95 | 0.521 | 0.884 | 1.000 |
84 | raccycdPathway | | 22 | 0.28 | 0.95 | 0.530 | 0.890 | 1.000 |
85 | ptdinsPathway | | 20 | 0.31 | 0.94 | 0.539 | 0.890 | 1.000 |
86 | nos1Pathway | | 21 | 0.29 | 0.94 | 0.558 | 0.886 | 1.000 |
87 | ANDROGEN_GENES_FROM_NETAFFX | | 53 | 0.25 | 0.94 | 0.552 | 0.880 | 1.000 |
88 | GO_0005739 | | 144 | 0.24 | 0.94 | 0.514 | 0.870 | 1.000 |
89 | electron_transport | | 62 | 0.25 | 0.94 | 0.550 | 0.867 | 1.000 |
90 | ST_Fas_Signaling_Pathway | | 56 | 0.24 | 0.93 | 0.544 | 0.871 | 1.000 |
91 | ANTI_CD44_UP | | 23 | 0.29 | 0.92 | 0.573 | 0.892 | 1.000 |
92 | MAP00190_Oxidative_phosphorylation | | 41 | 0.31 | 0.91 | 0.574 | 0.896 | 1.000 |
93 | cell_growth_and_or_maintenance | | 55 | 0.25 | 0.91 | 0.570 | 0.891 | 1.000 |
94 | INSULIN_2F_DOWN | | 27 | 0.27 | 0.90 | 0.607 | 0.897 | 1.000 |
95 | rhoPathway | | 30 | 0.27 | 0.90 | 0.586 | 0.893 | 1.000 |
96 | FRASOR_ER_UP | | 31 | 0.29 | 0.90 | 0.592 | 0.889 | 1.000 |
97 | tob1Pathway | | 18 | 0.37 | 0.89 | 0.606 | 0.890 | 1.000 |
98 | INS | | 24 | 0.28 | 0.88 | 0.616 | 0.902 | 1.000 |
99 | ADULT_LIVER_vs_FETAL_LIVER_GNF2 | | 61 | 0.26 | 0.87 | 0.650 | 0.912 | 1.000 |
100 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | | 25 | 0.27 | 0.87 | 0.652 | 0.903 | 1.000 |
101 | telPathway | | 18 | 0.30 | 0.87 | 0.618 | 0.902 | 1.000 |
102 | MAP00380_Tryptophan_metabolism | | 42 | 0.25 | 0.86 | 0.654 | 0.908 | 1.000 |
103 | MAP00071_Fatty_acid_metabolism | | 43 | 0.25 | 0.86 | 0.651 | 0.901 | 1.000 |
104 | MAP00620_Pyruvate_metabolism | | 30 | 0.26 | 0.86 | 0.643 | 0.901 | 1.000 |
105 | mcalpainPathway | | 23 | 0.29 | 0.85 | 0.665 | 0.901 | 1.000 |
106 | actinYPathway | | 18 | 0.29 | 0.85 | 0.647 | 0.898 | 1.000 |
107 | AR_MOUSE_PLUS_TESTO_FROM_NETAFFX | | 50 | 0.23 | 0.84 | 0.713 | 0.918 | 1.000 |
108 | cell_proliferation | | 200 | 0.17 | 0.83 | 0.870 | 0.925 | 1.000 |
109 | SA_CASPASE_CASCADE | | 17 | 0.32 | 0.82 | 0.678 | 0.924 | 1.000 |
110 | ctla4Pathway | | 19 | 0.38 | 0.82 | 0.679 | 0.923 | 1.000 |
111 | MAP00010_Glycolysis_Gluconeogenesis | | 49 | 0.22 | 0.82 | 0.752 | 0.920 | 1.000 |
112 | ST_Ga12_Pathway | | 21 | 0.27 | 0.81 | 0.734 | 0.926 | 1.000 |
113 | MAP00650_Butanoate_metabolism | | 19 | 0.26 | 0.81 | 0.705 | 0.919 | 1.000 |
114 | CR_TRANSCRIPTION_FACTORS | | 67 | 0.21 | 0.81 | 0.806 | 0.912 | 1.000 |
115 | cellcyclePathway | | 23 | 0.27 | 0.78 | 0.729 | 0.949 | 1.000 |
116 | GO_ROS | | 23 | 0.24 | 0.77 | 0.806 | 0.959 | 1.000 |
117 | MAP00910_Nitrogen_metabolism | | 19 | 0.26 | 0.77 | 0.776 | 0.962 | 1.000 |
118 | MAP00360_Phenylalanine_metabolism | | 16 | 0.29 | 0.77 | 0.745 | 0.954 | 1.000 |
119 | pparaPathway | | 49 | 0.20 | 0.76 | 0.883 | 0.949 | 1.000 |
120 | SA_MMP_CYTOKINE_CONNECTION | | 15 | 0.29 | 0.76 | 0.790 | 0.947 | 1.000 |
121 | HOX_LIST_JP | | 42 | 0.22 | 0.75 | 0.804 | 0.957 | 1.000 |
122 | EMT_UP | | 53 | 0.25 | 0.74 | 0.769 | 0.956 | 1.000 |
123 | mitochondr | | 330 | 0.18 | 0.73 | 0.788 | 0.966 | 1.000 |
124 | CR_CAM | | 89 | 0.19 | 0.73 | 0.928 | 0.959 | 1.000 |
125 | MAP00640_Propanoate_metabolism | | 19 | 0.23 | 0.73 | 0.820 | 0.953 | 1.000 |
126 | ST_G_alpha_i_Pathway_ | | 34 | 0.20 | 0.73 | 0.887 | 0.949 | 1.000 |
127 | cardiacegfPathway | | 16 | 0.24 | 0.69 | 0.892 | 0.983 | 1.000 |
128 | AR_ORTHOS_MAPPED_TO_U133_VIA_NETAFFX | | 38 | 0.20 | 0.69 | 0.915 | 0.978 | 1.000 |
129 | AR_MOUSE | | 38 | 0.20 | 0.69 | 0.915 | 0.970 | 1.000 |
130 | LEU_UP | | 114 | 0.17 | 0.69 | 0.921 | 0.969 | 1.000 |
131 | shh_lisa | | 17 | 0.22 | 0.68 | 0.877 | 0.966 | 1.000 |
132 | human_mitoDB_6_2002 | | 326 | 0.17 | 0.68 | 0.836 | 0.959 | 1.000 |
133 | igf1mtorPathway | | 19 | 0.22 | 0.67 | 0.874 | 0.965 | 1.000 |
134 | TGF_Beta_Signaling_Pathway | | 34 | 0.20 | 0.66 | 0.914 | 0.968 | 1.000 |
135 | KRAS_TOP100_CONTROL | | 56 | 0.17 | 0.65 | 0.978 | 0.970 | 1.000 |
136 | CR_REPAIR | | 39 | 0.21 | 0.63 | 0.833 | 0.977 | 1.000 |
137 | MAP00710_Carbon_fixation | | 16 | 0.21 | 0.63 | 0.940 | 0.974 | 1.000 |
138 | Krebs-TCA_Cycle | | 25 | 0.22 | 0.62 | 0.898 | 0.973 | 1.000 |
139 | ST_T_Cell_Signal_Transduction | | 39 | 0.20 | 0.59 | 0.889 | 0.983 | 1.000 |
140 | SIG_BCR_Signaling_Pathway | | 44 | 0.15 | 0.58 | 0.996 | 0.979 | 1.000 |
141 | KRAS_TOP100_KNOCKDOWN | | 72 | 0.20 | 0.58 | 0.905 | 0.976 | 1.000 |
142 | MAP00330_Arginine_and_proline_metabolism | | 38 | 0.17 | 0.57 | 0.969 | 0.969 | 1.000 |
143 | VOXPHOS | | 66 | 0.16 | 0.47 | 0.943 | 0.992 | 1.000 |
Table: Gene sets enriched in phenotype WT (17 samples) [plain text format]