Details for gene set GPCRs_Class_A

Table: GSEA Results Summary

Dataset	p53_full_useme_maxed_cs.gct
Phenotype	WT
GeneSet	s2.symbols.gmt#GPCRs_Class_A_Rhodopsin-like
Enrichment Score (ES)	0.42651632
Normalized Enrichment Score (NES)	1.4715267
Nominal p-value	0.062305298
FDR q-value	0.6924941
FWER p-Value	0.991

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RES	CORE_ENRICHMENT
1	NTSR2	NTSR2 StanfordSource, GeneCards	neurotensin receptor 2	29	0.483	0.0259	Yes
2	F2RL2	F2RL2 StanfordSource, GeneCards	coagulation factor II (thrombin) receptor-like 2	93	0.404	0.0437	Yes
3	ADRA2A	ADRA2A StanfordSource, GeneCards	adrenergic, alpha-2A-, receptor	133	0.387	0.0629	Yes
4	CCBP2	CCBP2 StanfordSource, GeneCards	chemokine binding protein 2	145	0.384	0.0847	Yes
5	MTNR1B	MTNR1B StanfordSource, GeneCards	melatonin receptor 1B	180	0.366	0.1031	Yes
6	HTR4	HTR4 StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 4	260	0.340	0.1155	Yes
7	GPR50	GPR50 StanfordSource, GeneCards	G protein-coupled receptor 50	293	0.333	0.1321	Yes
8	CCR8	CCR8 StanfordSource, GeneCards	chemokine (C-C motif) receptor 8	339	0.324	0.1469	Yes
9	CCR2	CCR2 StanfordSource, GeneCards	chemokine (C-C motif) receptor 2	384	0.316	0.1613	Yes
10	HTR1B	HTR1B StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 1B	428	0.310	0.1755	Yes
11	DRD1	DRD1 StanfordSource, GeneCards	dopamine receptor D1	553	0.290	0.1804	Yes
12	HTR2C	HTR2C StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 2C	556	0.290	0.1974	Yes
13	MC1R	MC1R StanfordSource, GeneCards	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	568	0.287	0.2134	Yes
14	CCKBR	CCKBR StanfordSource, GeneCards	cholecystokinin B receptor	603	0.283	0.2269	Yes
15	GPR44	GPR44 StanfordSource, GeneCards	G protein-coupled receptor 44	607	0.283	0.2435	Yes
16	EDNRA	EDNRA StanfordSource, GeneCards	endothelin receptor type A	638	0.278	0.2571	Yes
17	DRD3	DRD3 StanfordSource, GeneCards	dopamine receptor D3	671	0.274	0.2702	Yes
18	OPRD1	OPRD1 StanfordSource, GeneCards	opioid receptor, delta 1	689	0.272	0.2847	Yes
19	ADORA1	ADORA1 StanfordSource, GeneCards	adenosine A1 receptor	694	0.271	0.3005	Yes
20	AGTR2	AGTR2 StanfordSource, GeneCards	angiotensin II receptor, type 2	705	0.270	0.3156	Yes
21	GPR23	GPR23 StanfordSource, GeneCards	G protein-coupled receptor 23	706	0.270	0.3316	Yes
22	ADRA1D	ADRA1D StanfordSource, GeneCards	adrenergic, alpha-1D-, receptor	754	0.264	0.3427	Yes
23	HTR2B	HTR2B StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 2B	853	0.253	0.3479	Yes
24	CMKOR1	CMKOR1 StanfordSource, GeneCards	chemokine orphan receptor 1	914	0.248	0.3567	Yes
25	CXCR3	CXCR3 StanfordSource, GeneCards	chemokine (C-X-C motif) receptor 3	992	0.242	0.3634	Yes
26	HTR7	HTR7 StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	1021	0.240	0.3749	Yes
27	BDKRB1	BDKRB1 StanfordSource, GeneCards	bradykinin receptor B1	1035	0.238	0.3878	Yes
28	RRH	RRH StanfordSource, GeneCards	retinal pigment epithelium-derived rhodopsin homolog	1037	0.238	0.4018	Yes
29	PPYR1	PPYR1 StanfordSource, GeneCards	pancreatic polypeptide receptor 1	1122	0.232	0.4072	Yes
30	ADRB1	ADRB1 StanfordSource, GeneCards	adrenergic, beta-1-, receptor	1152	0.229	0.4180	Yes
31	NMBR	NMBR StanfordSource, GeneCards	neuromedin B receptor	1320	0.219	0.4143	Yes
32	OPRL1	OPRL1 StanfordSource, GeneCards	opiate receptor-like 1	1728	0.191	0.3850	Yes
33	GALR3	GALR3 StanfordSource, GeneCards	galanin receptor 3	1746	0.190	0.3946	Yes
34	RGR	RGR StanfordSource, GeneCards	retinal G protein coupled receptor	1808	0.186	0.3996	Yes
35	ADRA2C	ADRA2C StanfordSource, GeneCards	adrenergic, alpha-2C-, receptor	1968	0.177	0.3942	Yes
36	FPRL2	FPRL2 StanfordSource, GeneCards	formyl peptide receptor-like 2	1991	0.175	0.4025	Yes
37	EDNRB	EDNRB StanfordSource, GeneCards	endothelin receptor type B	2097	0.169	0.4020	Yes
38	CNR2	CNR2 StanfordSource, GeneCards	cannabinoid receptor 2 (macrophage)	2123	0.168	0.4095	Yes
39	FPRL1	FPRL1 StanfordSource, GeneCards	formyl peptide receptor-like 1	2131	0.167	0.4188	Yes
40	CCR1	CCR1 StanfordSource, GeneCards	chemokine (C-C motif) receptor 1	2235	0.161	0.4180	Yes
41	TBXA2R	TBXA2R StanfordSource, GeneCards	thromboxane A2 receptor	2279	0.158	0.4232	Yes
42	C3AR1	C3AR1 StanfordSource, GeneCards	complement component 3a receptor 1	2394	0.152	0.4208	Yes
43	GPR30	GPR30 StanfordSource, GeneCards	G protein-coupled receptor 30	2430	0.150	0.4262	Yes
44	HTR2A	HTR2A StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 2A	2515	0.146	0.4265	Yes
45	NPY2R	NPY2R StanfordSource, GeneCards	neuropeptide Y receptor Y2	2650	0.138	0.4213	No
46	CCR7	CCR7 StanfordSource, GeneCards	chemokine (C-C motif) receptor 7	2794	0.131	0.4148	No
47	PTGIR	PTGIR StanfordSource, GeneCards	prostaglandin I2 (prostacyclin) receptor (IP)	3004	0.121	0.4011	No
48	DRD2	DRD2 StanfordSource, GeneCards	dopamine receptor D2	3029	0.120	0.4059	No
49	CCR4	CCR4 StanfordSource, GeneCards	chemokine (C-C motif) receptor 4	3143	0.114	0.4014	No
50	CXCR4	CXCR4 StanfordSource, GeneCards	chemokine (C-X-C motif) receptor 4	3318	0.106	0.3903	No
51	AVPR2	AVPR2 StanfordSource, GeneCards	arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)	3413	0.101	0.3870	No
52	NPY5R	NPY5R StanfordSource, GeneCards	neuropeptide Y receptor Y5	3424	0.101	0.3920	No
53	PTAFR	PTAFR StanfordSource, GeneCards	platelet-activating factor receptor	3582	0.093	0.3818	No
54	OPRM1	OPRM1 StanfordSource, GeneCards	opioid receptor, mu 1	3594	0.093	0.3863	No
55	PTGDR	PTGDR StanfordSource, GeneCards	prostaglandin D2 receptor (DP)	3651	0.090	0.3860	No
56	CCKAR	CCKAR StanfordSource, GeneCards	cholecystokinin A receptor	3886	0.080	0.3674	No
57	TRHR	TRHR StanfordSource, GeneCards	thyrotropin-releasing hormone receptor	4116	0.069	0.3485	No
58	GPR35	GPR35 StanfordSource, GeneCards	G protein-coupled receptor 35	4223	0.064	0.3418	No
59	GPR17	GPR17 StanfordSource, GeneCards	G protein-coupled receptor 17	4276	0.062	0.3403	No
60	NPY6R	NPY6R StanfordSource, GeneCards	neuropeptide Y receptor Y6 (pseudogene)	4438	0.056	0.3275	No
61	CCR9	CCR9 StanfordSource, GeneCards	chemokine (C-C motif) receptor 9	4506	0.053	0.3239	No
62	PTGER1	PTGER1 StanfordSource, GeneCards	prostaglandin E receptor 1 (subtype EP1), 42kDa	4659	0.046	0.3114	No
63	FPR1	FPR1 StanfordSource, GeneCards	formyl peptide receptor 1	4747	0.042	0.3052	No
64	IL8RB	IL8RB StanfordSource, GeneCards	interleukin 8 receptor, beta	4753	0.042	0.3072	No
65	LTB4R	LTB4R StanfordSource, GeneCards	leukotriene B4 receptor	4765	0.041	0.3086	No
66	CCR5	CCR5 StanfordSource, GeneCards	chemokine (C-C motif) receptor 5	4854	0.037	0.3020	No
67	AGTRL1	AGTRL1 StanfordSource, GeneCards	angiotensin II receptor-like 1	5227	0.021	0.2660	No
68	IL8RA	IL8RA StanfordSource, GeneCards	interleukin 8 receptor, alpha	5239	0.021	0.2662	No
69	ADRB3	ADRB3 StanfordSource, GeneCards	adrenergic, beta-3-, receptor	5411	0.014	0.2499	No
70	P2RY6	P2RY6 StanfordSource, GeneCards	pyrimidinergic receptor P2Y, G-protein coupled, 6	5430	0.013	0.2488	No
71	CMKLR1	CMKLR1 StanfordSource, GeneCards	chemokine-like receptor 1	5450	0.012	0.2476	No
72	FSHR	FSHR StanfordSource, GeneCards	follicle stimulating hormone receptor	5473	0.011	0.2461	No
73	OPRK1	OPRK1 StanfordSource, GeneCards	opioid receptor, kappa 1	5499	0.010	0.2441	No
74	GALR2	GALR2 StanfordSource, GeneCards	galanin receptor 2	5505	0.009	0.2442	No
75	GPR4	GPR4 StanfordSource, GeneCards	G protein-coupled receptor 4	5539	0.008	0.2414	No
76	AVPR1B	AVPR1B StanfordSource, GeneCards	arginine vasopressin receptor 1B	5791	-0.004	0.2165	No
77	TSHR	TSHR StanfordSource, GeneCards	thyroid stimulating hormone receptor	6016	-0.013	0.1948	No
78	AGTR1	AGTR1 StanfordSource, GeneCards	angiotensin II receptor, type 1	6024	-0.014	0.1949	No
79	AVPR1A	AVPR1A StanfordSource, GeneCards	arginine vasopressin receptor 1A	6033	-0.014	0.1950	No
80	HRH1	HRH1 StanfordSource, GeneCards	histamine receptor H1	6133	-0.020	0.1862	No
81	MAS1	MAS1 StanfordSource, GeneCards	MAS1 oncogene	6155	-0.021	0.1854	No
82	P2RY1	P2RY1 StanfordSource, GeneCards	purinergic receptor P2Y, G-protein coupled, 1	6180	-0.022	0.1843	No
83	ADORA3	ADORA3 StanfordSource, GeneCards	adenosine A3 receptor	6192	-0.023	0.1845	No
84	ADRA1A	ADRA1A StanfordSource, GeneCards	adrenergic, alpha-1A-, receptor	6418	-0.033	0.1640	No
85	BDKRB2	BDKRB2 StanfordSource, GeneCards	bradykinin receptor B2	6449	-0.034	0.1630	No
86	GRPR	GRPR StanfordSource, GeneCards	gastrin-releasing peptide receptor	6477	-0.036	0.1625	No
87	F2RL1	F2RL1 StanfordSource, GeneCards	coagulation factor II (thrombin) receptor-like 1	6602	-0.041	0.1525	No
88	ADORA2A	ADORA2A StanfordSource, GeneCards	adenosine A2a receptor	6625	-0.042	0.1528	No
89	ADRB2	ADRB2 StanfordSource, GeneCards	adrenergic, beta-2-, receptor, surface	6776	-0.050	0.1407	No
90	HTR1D	HTR1D StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 1D	6886	-0.056	0.1331	No
91	ADRA1B	ADRA1B StanfordSource, GeneCards	adrenergic, alpha-1B-, receptor	6938	-0.058	0.1315	No
92	PTGER2	PTGER2 StanfordSource, GeneCards	prostaglandin E receptor 2 (subtype EP2), 53kDa	6975	-0.060	0.1315	No
93	HTR1E	HTR1E StanfordSource, GeneCards	5-hydroxytryptamine (serotonin) receptor 1E	7173	-0.070	0.1159	No
94	NTSR1	NTSR1 StanfordSource, GeneCards	neurotensin receptor 1 (high affinity)	7478	-0.087	0.0906	No
95	GPR37	GPR37 StanfordSource, GeneCards	G protein-coupled receptor 37 (endothelin receptor type B-like)	7513	-0.088	0.0925	No
96	HCRTR1	HCRTR1 StanfordSource, GeneCards	hypocretin (orexin) receptor 1	7569	-0.091	0.0924	No
97	LHCGR	LHCGR StanfordSource, GeneCards	luteinizing hormone/choriogonadotropin receptor	7630	-0.094	0.0919	No
98	PTGER3	PTGER3 StanfordSource, GeneCards	prostaglandin E receptor 3 (subtype EP3)	7655	-0.096	0.0952	No
99	HCRTR2	HCRTR2 StanfordSource, GeneCards	hypocretin (orexin) receptor 2	7660	-0.096	0.1006	No
100	BLR1	BLR1 StanfordSource, GeneCards	Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)	7717	-0.099	0.1008	No
101	F2R	F2R StanfordSource, GeneCards	coagulation factor II (thrombin) receptor	7881	-0.108	0.0910	No
102	PTGER4	PTGER4 StanfordSource, GeneCards	prostaglandin E receptor 4 (subtype EP4)	8243	-0.131	0.0626	No
103	VIPR1	VIPR1 StanfordSource, GeneCards	vasoactive intestinal peptide receptor 1	8483	-0.148	0.0475	No
104	CCR3	CCR3 StanfordSource, GeneCards	chemokine (C-C motif) receptor 3	8524	-0.150	0.0524	No
105	CCRL2	CCRL2 StanfordSource, GeneCards	chemokine (C-C motif) receptor-like 2	9246	-0.204	-0.0076	No
106	P2RY2	P2RY2 StanfordSource, GeneCards	purinergic receptor P2Y, G-protein coupled, 2	9348	-0.215	-0.0048	No
107	CX3CR1	CX3CR1 StanfordSource, GeneCards	chemokine (C-X3-C motif) receptor 1	9410	-0.222	0.0023	No
108	DRD4	DRD4 StanfordSource, GeneCards	dopamine receptor D4	9424	-0.224	0.0144	No
109	CNR1	CNR1 StanfordSource, GeneCards	cannabinoid receptor 1 (brain)	9496	-0.233	0.0212	No
110	PTGFR	PTGFR StanfordSource, GeneCards	prostaglandin F receptor (FP)	9574	-0.246	0.0281	No
111	ADORA2B	ADORA2B StanfordSource, GeneCards	adenosine A2b receptor	10066	-0.409	0.0033	No