Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | WT |
| GeneSet | s2.symbols.gmt#ST_Interleukin_4_Pathway |
| Enrichment Score (ES) | 0.4032152 |
| Normalized Enrichment Score (NES) | 1.3417566 |
| Nominal p-value | 0.09965035 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | STAT6 | STAT6 StanfordSource, GeneCards | signal transducer and activator of transcription 6, interleukin-4 induced | 5 | 0.579 | 0.1597 | Yes |
| 2 | SRC | SRC StanfordSource, GeneCards | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 191 | 0.362 | 0.2413 | Yes |
| 3 | IL4 | IL4 StanfordSource, GeneCards | interleukin 4 | 206 | 0.354 | 0.3379 | Yes |
| 4 | JAK3 | JAK3 StanfordSource, GeneCards | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 416 | 0.311 | 0.4032 | Yes |
| 5 | IL4R | IL4R StanfordSource, GeneCards | interleukin 4 receptor | 1378 | 0.215 | 0.3673 | No |
| 6 | JAK2 | JAK2 StanfordSource, GeneCards | Janus kinase 2 (a protein tyrosine kinase) | 2039 | 0.173 | 0.3495 | No |
| 7 | RPS6KB1 | RPS6KB1 StanfordSource, GeneCards | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 2460 | 0.148 | 0.3489 | No |
| 8 | AKT3 | AKT3 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 2743 | 0.133 | 0.3578 | No |
| 9 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 3184 | 0.112 | 0.3452 | No |
| 10 | INPP5D | INPP5D StanfordSource, GeneCards | inositol polyphosphate-5-phosphatase, 145kDa | 4090 | 0.070 | 0.2748 | No |
| 11 | GRB2 | GRB2 StanfordSource, GeneCards | growth factor receptor-bound protein 2 | 4102 | 0.070 | 0.2930 | No |
| 12 | PI3 | PI3 StanfordSource, GeneCards | protease inhibitor 3, skin-derived (SKALP) | 4293 | 0.061 | 0.2911 | No |
| 13 | IL2RG | IL2RG StanfordSource, GeneCards | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 5147 | 0.025 | 0.2133 | No |
| 14 | JAK1 | JAK1 StanfordSource, GeneCards | Janus kinase 1 (a protein tyrosine kinase) | 5657 | 0.002 | 0.1634 | No |
| 15 | SERPINA4 | SERPINA4 StanfordSource, GeneCards | serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 | 5816 | -0.005 | 0.1490 | No |
| 16 | SHC1 | SHC1 StanfordSource, GeneCards | SHC (Src homology 2 domain containing) transforming protein 1 | 6401 | -0.032 | 0.0999 | No |
| 17 | NR0B2 | NR0B2 StanfordSource, GeneCards | nuclear receptor subfamily 0, group B, member 2 | 6614 | -0.042 | 0.0903 | No |
| 18 | IARS | IARS StanfordSource, GeneCards | isoleucine-tRNA synthetase | 7132 | -0.068 | 0.0577 | No |
| 19 | IL13RA1 | IL13RA1 StanfordSource, GeneCards | interleukin 13 receptor, alpha 1 | 7139 | -0.068 | 0.0760 | No |
| 20 | AKT2 | AKT2 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 2 | 7281 | -0.075 | 0.0828 | No |
| 21 | PPP1R13B | PPP1R13B StanfordSource, GeneCards | protein phosphatase 1, regulatory (inhibitor) subunit 13B | 7989 | -0.114 | 0.0440 | No |
| 22 | TYK2 | TYK2 StanfordSource, GeneCards | tyrosine kinase 2 | 8006 | -0.114 | 0.0741 | No |
| 23 | SOS1 | SOS1 StanfordSource, GeneCards | son of sevenless homolog 1 (Drosophila) | 8043 | -0.116 | 0.1026 | No |
| 24 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 10023 | -0.366 | 0.0075 | No |
