| GS | GS DESC | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | 1 | TESTIS_GENES_FROM_XHX_AND_NETAFFX | Details ... | 73 | 0.61 | 1.86 | 0.000 | 0.068 | 0.085 |
2 | MAP00650_Butanoate_metabolism | Details ... | 20 | 0.52 | 1.50 | 0.053 | 1.000 | 0.822 |
3 | NFKB_REDUCED | Details ... | 21 | 0.55 | 1.44 | 0.067 | 1.000 | 0.893 |
4 | ST_Wnt_Ca2_cyclic_GMP_Pathway | Details ... | 19 | 0.48 | 1.41 | 0.102 | 1.000 | 0.910 |
5 | lairPathway | Details ... | 16 | 0.47 | 1.40 | 0.087 | 1.000 | 0.916 |
6 | shhPathway | Details ... | 15 | 0.49 | 1.34 | 0.112 | 1.000 | 0.947 |
7 | CR_CAM | Details ... | 92 | 0.33 | 1.33 | 0.096 | 1.000 | 0.951 |
8 | KRAS_TOP100_KNOCKDOWN | Details ... | 84 | 0.35 | 1.33 | 0.099 | 1.000 | 0.951 |
9 | gata3Pathway | Details ... | 15 | 0.42 | 1.32 | 0.104 | 1.000 | 0.953 |
10 | ANTI_CD44_UP | Details ... | 23 | 0.46 | 1.30 | 0.152 | 1.000 | 0.956 |
11 | AR_ORTHOS_MAPPED_TO_U133_VIA_NETAFFX | Details ... | 46 | 0.37 | 1.30 | 0.108 | 1.000 | 0.957 |
12 | AR_MOUSE | Details ... | 46 | 0.37 | 1.30 | 0.108 | 1.000 | 0.957 |
13 | EMT_DOWN | Details ... | 39 | 0.39 | 1.25 | 0.168 | 1.000 | 0.964 |
14 | AR_MOUSE_PLUS_TESTO_FROM_NETAFFX | Details ... | 62 | 0.33 | 1.24 | 0.139 | 1.000 | 0.966 |
15 | ANDROGEN_GENES_FROM_NETAFFX | Details ... | 62 | 0.32 | 1.23 | 0.171 | 1.000 | 0.970 |
16 | ST_T_Cell_Signal_Transduction | Details ... | 42 | 0.33 | 1.21 | 0.197 | 1.000 | 0.974 |
17 | cell_adhesion | Details ... | 182 | 0.30 | 1.20 | 0.167 | 1.000 | 0.976 |
18 | inflamPathway | Details ... | 28 | 0.38 | 1.19 | 0.213 | 1.000 | 0.978 |
19 | Inflammatory_Response_Pathway | Details ... | 26 | 0.38 | 1.16 | 0.245 | 1.000 | 0.979 |
20 | nktPathway | Details ... | 27 | 0.38 | 1.16 | 0.283 | 1.000 | 0.979 |
21 | MAP00590_Prostaglandin_and_leukotriene_metabolism | | 19 | 0.38 | 1.15 | 0.269 | 1.000 | 0.980 |
22 | electron_transport | | 74 | 0.30 | 1.15 | 0.252 | 1.000 | 0.980 |
23 | nos1Pathway | | 22 | 0.35 | 1.15 | 0.279 | 1.000 | 0.980 |
24 | cell_surface_receptor_linked_signal_transduction | | 135 | 0.29 | 1.15 | 0.242 | 1.000 | 0.980 |
25 | P53_DOWN | | 18 | 0.38 | 1.15 | 0.281 | 1.000 | 0.981 |
26 | GPCRs_Class_A_Rhodopsin-like | | 134 | 0.33 | 1.14 | 0.348 | 1.000 | 0.981 |
27 | edg1Pathway | | 25 | 0.38 | 1.13 | 0.327 | 1.000 | 0.981 |
28 | GPCRs_Class_B_Secretin-like | | 23 | 0.40 | 1.12 | 0.336 | 1.000 | 0.983 |
29 | MAP00410_beta_Alanine_metabolism | | 17 | 0.37 | 1.11 | 0.306 | 1.000 | 0.983 |
30 | FRASOR_ER_DOWN | | 68 | 0.30 | 1.11 | 0.315 | 1.000 | 0.983 |
31 | NFKB_INDUCED | | 108 | 0.27 | 1.10 | 0.306 | 1.000 | 0.984 |
32 | MAP00220_Urea_cycle_and_metabolism_of_amino_groups | | 18 | 0.39 | 1.10 | 0.365 | 1.000 | 0.984 |
33 | ccr5Pathway | | 18 | 0.37 | 1.10 | 0.367 | 1.000 | 0.984 |
34 | Il12Pathway | | 22 | 0.36 | 1.09 | 0.381 | 1.000 | 0.986 |
35 | il1rPathway | | 32 | 0.34 | 1.08 | 0.372 | 1.000 | 0.986 |
36 | cell_adhesion_molecule_activity | | 107 | 0.27 | 1.07 | 0.368 | 1.000 | 0.986 |
37 | vipPathway | | 26 | 0.34 | 1.07 | 0.383 | 1.000 | 0.986 |
38 | muscle_myosin | | 15 | 0.38 | 1.06 | 0.378 | 1.000 | 0.986 |
39 | il7Pathway | | 16 | 0.43 | 1.06 | 0.403 | 1.000 | 0.987 |
40 | MAP00350_Tyrosine_metabolism | | 29 | 0.35 | 1.05 | 0.391 | 1.000 | 0.989 |
41 | ST_Ga13_Pathway | | 35 | 0.33 | 1.05 | 0.421 | 1.000 | 0.989 |
42 | MAP00280_Valine_leucine_and_isoleucine_degradation | | 25 | 0.34 | 1.05 | 0.412 | 1.000 | 0.989 |
43 | ST_Gaq_Pathway | | 27 | 0.34 | 1.04 | 0.405 | 1.000 | 0.989 |
44 | mef2dPathway | | 19 | 0.37 | 1.04 | 0.421 | 1.000 | 0.989 |
45 | ucalpainPathway | | 15 | 0.40 | 1.03 | 0.456 | 1.000 | 0.991 |
46 | MAP00071_Fatty_acid_metabolism | | 44 | 0.31 | 1.03 | 0.431 | 1.000 | 0.992 |
47 | tcrPathway | | 45 | 0.30 | 1.03 | 0.455 | 1.000 | 0.993 |
48 | tob1Pathway | | 18 | 0.35 | 1.03 | 0.417 | 1.000 | 0.993 |
49 | EMT_UP | | 56 | 0.27 | 1.03 | 0.413 | 1.000 | 0.993 |
50 | GATA1_WEISS | | 24 | 0.32 | 1.02 | 0.437 | 1.000 | 0.994 |
51 | ADULT_LIVER_vs_FETAL_LIVER_GNF2 | | 80 | 0.25 | 1.02 | 0.417 | 1.000 | 0.994 |
52 | MAP00360_Phenylalanine_metabolism | | 16 | 0.40 | 1.01 | 0.470 | 1.000 | 0.994 |
53 | alkPathway | | 32 | 0.32 | 1.00 | 0.476 | 1.000 | 0.994 |
54 | il17Pathway | | 17 | 0.35 | 0.99 | 0.468 | 1.000 | 0.994 |
55 | cytokinePathway | | 20 | 0.35 | 0.98 | 0.494 | 1.000 | 0.994 |
56 | ST_ADRENERGIC | | 36 | 0.29 | 0.98 | 0.515 | 1.000 | 0.994 |
57 | compPathway | | 16 | 0.38 | 0.97 | 0.501 | 1.000 | 0.994 |
58 | RAR_UP | | 35 | 0.30 | 0.96 | 0.525 | 1.000 | 0.994 |
59 | CR_DEATH | | 75 | 0.27 | 0.96 | 0.526 | 1.000 | 0.995 |
60 | ST_MONOCYTE_AD_PATHWAY | | 27 | 0.29 | 0.96 | 0.546 | 1.000 | 0.995 |
61 | mprPathway | | 23 | 0.30 | 0.95 | 0.532 | 1.000 | 0.995 |
62 | SA_CASPASE_CASCADE | | 18 | 0.35 | 0.95 | 0.578 | 1.000 | 0.995 |
63 | breast_cancer_estrogen_signalling | | 99 | 0.23 | 0.95 | 0.571 | 1.000 | 0.995 |
64 | par1Pathway | | 20 | 0.35 | 0.94 | 0.527 | 1.000 | 0.995 |
65 | electron_transporter_activity | | 117 | 0.23 | 0.93 | 0.613 | 1.000 | 0.995 |
66 | tnf_and_fas_network | | 21 | 0.30 | 0.91 | 0.587 | 1.000 | 0.996 |
67 | MAP00052_Galactose_metabolism | | 23 | 0.33 | 0.91 | 0.580 | 1.000 | 0.996 |
68 | no2il12Pathway | | 16 | 0.31 | 0.90 | 0.582 | 1.000 | 0.996 |
69 | CR_SIGNALLING | | 182 | 0.23 | 0.90 | 0.625 | 1.000 | 0.996 |
70 | pitx2Pathway | | 16 | 0.35 | 0.90 | 0.589 | 1.000 | 0.996 |
71 | mcalpainPathway | | 23 | 0.29 | 0.90 | 0.594 | 1.000 | 0.996 |
72 | ca_nf_at_signalling | | 94 | 0.23 | 0.90 | 0.623 | 1.000 | 0.996 |
73 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | | 27 | 0.30 | 0.90 | 0.637 | 1.000 | 0.996 |
74 | stemPathway | | 15 | 0.34 | 0.90 | 0.574 | 1.000 | 0.996 |
75 | MAP00252_Alanine_and_aspartate_metabolism | | 21 | 0.31 | 0.89 | 0.629 | 1.000 | 0.997 |
76 | calcineurinPathway | | 18 | 0.30 | 0.89 | 0.621 | 1.000 | 0.997 |
77 | SA_TRKA_RECEPTOR | | 16 | 0.32 | 0.89 | 0.603 | 1.000 | 0.997 |
78 | atmPathway | | 20 | 0.34 | 0.88 | 0.588 | 1.000 | 0.997 |
79 | cell_adhesion_receptor_activity | | 34 | 0.26 | 0.88 | 0.645 | 1.000 | 0.997 |
80 | HOX_LIST_JP | | 56 | 0.25 | 0.88 | 0.664 | 1.000 | 0.997 |
81 | ccr3Pathway | | 22 | 0.26 | 0.88 | 0.651 | 1.000 | 0.997 |
82 | ceramidePathway | | 22 | 0.27 | 0.86 | 0.656 | 1.000 | 0.998 |
83 | ck1Pathway | | 16 | 0.29 | 0.86 | 0.644 | 1.000 | 0.998 |
84 | amiPathway | | 24 | 0.26 | 0.86 | 0.678 | 1.000 | 0.998 |
85 | cskPathway | | 24 | 0.26 | 0.86 | 0.678 | 1.000 | 0.998 |
86 | MAP00150_Androgen_and_estrogen_metabolism | | 17 | 0.30 | 0.86 | 0.646 | 1.000 | 0.998 |
87 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | | 27 | 0.26 | 0.84 | 0.691 | 1.000 | 0.999 |
88 | BRCA_UP | | 40 | 0.26 | 0.84 | 0.684 | 1.000 | 0.999 |
89 | MAP00361_gamma_Hexachlorocyclohexane_degradation | | 27 | 0.29 | 0.83 | 0.694 | 1.000 | 0.999 |
90 | ctlPathway | | 15 | 0.29 | 0.82 | 0.692 | 1.000 | 0.999 |
91 | th1th2Pathway | | 18 | 0.29 | 0.82 | 0.705 | 1.000 | 0.999 |
92 | ST_Wnt_beta_catenin_Pathway | | 29 | 0.24 | 0.82 | 0.709 | 1.000 | 0.999 |
93 | CR_IMMUNE_FUNCTION | | 51 | 0.23 | 0.82 | 0.774 | 1.000 | 0.999 |
94 | MAP00510_N_Glycans_biosynthesis | | 17 | 0.30 | 0.81 | 0.702 | 1.000 | 0.999 |
95 | intrinsicPathway | | 22 | 0.29 | 0.81 | 0.698 | 1.000 | 0.999 |
96 | wntPathway | | 25 | 0.26 | 0.81 | 0.720 | 1.000 | 0.999 |
97 | Eicosanoid_Synthesis | | 15 | 0.25 | 0.81 | 0.790 | 1.000 | 0.999 |
98 | p53hypoxiaPathway | | 20 | 0.28 | 0.80 | 0.740 | 1.000 | 0.999 |
99 | no1Pathway | | 29 | 0.23 | 0.78 | 0.782 | 1.000 | 0.999 |
100 | fasPathway | | 29 | 0.26 | 0.77 | 0.752 | 1.000 | 0.999 |
101 | badPathway | | 22 | 0.26 | 0.77 | 0.775 | 1.000 | 0.999 |
102 | gpcrPathway | | 34 | 0.23 | 0.77 | 0.789 | 1.000 | 0.999 |
103 | ST_Differentiation_Pathway_in_PC12_Cells | | 45 | 0.23 | 0.75 | 0.818 | 1.000 | 0.999 |
104 | HOXA9_DOWN | | 35 | 0.25 | 0.75 | 0.806 | 1.000 | 0.999 |
105 | ngfPathway | | 19 | 0.26 | 0.75 | 0.791 | 1.000 | 0.999 |
106 | nkcellsPathway | | 18 | 0.27 | 0.74 | 0.768 | 1.000 | 0.999 |
107 | MAP00500_Starch_and_sucrose_metabolism | | 21 | 0.27 | 0.74 | 0.802 | 1.000 | 0.999 |
108 | g2Pathway | | 23 | 0.30 | 0.74 | 0.733 | 1.000 | 0.999 |
109 | HTERT_DOWN | | 66 | 0.22 | 0.74 | 0.819 | 1.000 | 0.999 |
110 | MAP00860_Porphyrin_and_chlorophyll_metabolism | | 17 | 0.26 | 0.72 | 0.814 | 1.000 | 0.999 |
111 | ST_B_Cell_Antigen_Receptor | | 38 | 0.22 | 0.72 | 0.813 | 1.000 | 0.999 |
112 | cxcr4Pathway | | 23 | 0.24 | 0.72 | 0.835 | 1.000 | 0.999 |
113 | MAP00340_Histidine_metabolism | | 20 | 0.27 | 0.72 | 0.834 | 1.000 | 0.999 |
114 | ST_Tumor_Necrosis_Factor_Pathway | | 28 | 0.25 | 0.71 | 0.814 | 1.000 | 0.999 |
115 | DOWNREG_BY_HOXA9 | | 32 | 0.25 | 0.71 | 0.838 | 1.000 | 0.999 |
116 | FRASOR_ER_UP | | 31 | 0.20 | 0.69 | 0.899 | 1.000 | 0.999 |
117 | MAP00230_Purine_metabolism | | 82 | 0.19 | 0.68 | 0.884 | 1.000 | 0.999 |
118 | ST_Ga12_Pathway | | 23 | 0.22 | 0.68 | 0.897 | 1.000 | 0.999 |
119 | p53_signalling | | 95 | 0.20 | 0.68 | 0.874 | 1.000 | 0.999 |
120 | MAP00251_Glutamate_metabolism | | 20 | 0.25 | 0.67 | 0.850 | 1.000 | 0.999 |
121 | ST_ERK1_ERK2_MAPK_Pathway | | 31 | 0.20 | 0.67 | 0.909 | 1.000 | 0.999 |
122 | pyk2Pathway | | 28 | 0.23 | 0.67 | 0.859 | 1.000 | 0.999 |
123 | SIG_BCR_Signaling_Pathway | | 45 | 0.22 | 0.67 | 0.823 | 1.000 | 0.999 |
124 | pdgfPathway | | 27 | 0.23 | 0.67 | 0.865 | 1.000 | 0.999 |
125 | carm-erPathway | | 27 | 0.23 | 0.66 | 0.871 | 1.000 | 0.999 |
126 | MAP00380_Tryptophan_metabolism | | 44 | 0.19 | 0.66 | 0.923 | 1.000 | 0.999 |
127 | atrbrcaPathway | | 21 | 0.23 | 0.66 | 0.893 | 0.997 | 0.999 |
128 | fmlppathway | | 36 | 0.20 | 0.65 | 0.890 | 1.000 | 0.999 |
129 | shh_lisa | | 18 | 0.24 | 0.63 | 0.886 | 1.000 | 1.000 |
130 | at1rPathway | | 34 | 0.19 | 0.63 | 0.925 | 1.000 | 1.000 |
131 | GO_ROS | | 27 | 0.20 | 0.62 | 0.945 | 1.000 | 1.000 |
132 | ghPathway | | 27 | 0.20 | 0.62 | 0.914 | 1.000 | 1.000 |
133 | ST_Fas_Signaling_Pathway | | 62 | 0.19 | 0.61 | 0.943 | 0.998 | 1.000 |
134 | 41bbPathway | | 17 | 0.24 | 0.61 | 0.897 | 0.998 | 1.000 |
135 | nfkbPathway | | 23 | 0.19 | 0.59 | 0.950 | 1.000 | 1.000 |
136 | relaPathway | | 16 | 0.23 | 0.59 | 0.934 | 0.997 | 1.000 |
137 | integrinPathway | | 33 | 0.18 | 0.58 | 0.964 | 0.999 | 1.000 |
138 | MAP03020_RNA_polymerase | | 17 | 0.23 | 0.57 | 0.923 | 1.000 | 1.000 |
139 | egfPathway | | 27 | 0.19 | 0.56 | 0.941 | 1.000 | 1.000 |
140 | insulinPathway | | 21 | 0.20 | 0.55 | 0.951 | 0.996 | 1.000 |
141 | Fatty_Acid_Synthesis | | 15 | 0.23 | 0.55 | 0.932 | 0.993 | 1.000 |
142 | ctla4Pathway | | 21 | 0.18 | 0.54 | 0.960 | 0.989 | 1.000 |
143 | chrebpPathway | | 20 | 0.19 | 0.53 | 0.963 | 0.989 | 1.000 |
144 | bcrPathway | | 34 | 0.16 | 0.53 | 0.981 | 0.984 | 1.000 |
145 | SIG_CD40PATHWAYMAP | | 33 | 0.17 | 0.51 | 0.982 | 0.983 | 1.000 |
146 | nthiPathway | | 22 | 0.18 | 0.49 | 0.974 | 0.984 | 1.000 |
147 | fcer1Pathway | | 37 | 0.15 | 0.48 | 0.985 | 0.981 | 1.000 |
Table: Gene sets enriched in phenotype MALE (15 samples) [plain text format]