
DEPICT is an integrative tool that based on predicted gene functions systematically prioritizes the most likely causal genes at associated loci, highlights enriched pathways, and identifies tissues/cell types where genes from associated loci are highly expressed
Download DEPICT (2.9 GB) today
DEPICT for 1000 Genomes Project imputed meta-analysis data is currently being beta tested. Please send an email to tunepers@broadinstitute.org if you would like to try it out.
The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. DEPICT (Data-driven Expression-Prioritized Integration for Complex Traits) is a tool to inform experimental follow-up studies
Biological interpretation of genome-wide association studies using predicted gene functions Pers et al. Nature Communications 2015