DEPICT

"DEPICT" your association study

DEPICT is an integrative tool that based on predicted gene functions systematically prioritizes the most likely causal genes at associated loci, highlights enriched pathways, and identifies tissues/cell types where genes from associated loci are highly expressed

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DEPICT for 1000 Genomes Project imputed meta-analysis data is currently being beta tested. Please send an email to tunepers@broadinstitute.org if you would like to try it out.

From association towards biology

The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. DEPICT (Data-driven Expression-Prioritized Integration for Complex Traits) is a tool to inform experimental follow-up studies

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Citation

Biological interpretation of genome-wide association studies using predicted gene functions Pers et al. Nature Communications 2015

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