Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_AlanineAminotransferase_v2 11:22242646:C:CA 11 22242646 CA C 0.00303074 0.964303 57.6204 3.2E-14 0.148791 24.3 ANO5 frameshift won rs758504686 0.00168827385746 61.4095 0.00158410368064 -0.0166908 52.9825947477 rs12574283 70.7621 0.00134664779089 N/A N/A N/A N/A N/A biochemistry_AlanineAminotransferase_v2 11:93886737:G:T 11 93886737 T G 0.000153698 0.967518 32.2391 1.4E-08 -0.503767 24.3 PANX1 missense lost rs151234661 0.0341121645307 42.2262 0.026044149924 0.0891267 21.430058036 11:93866147:T:G 499.973 0.000998117649 PANX1 0.0002 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 19:4159747:G:A 19 4159747 A G 0.00213897 0.826363 36.4533 1.6E-09 -0.147806 22.8 CREB3L3 missense won rs475112 0.000305316950195 40.0268 0.00027805896001 0.0137884 35.1905093784 rs475112 40.0268 0.00027805896001 CREB3L3 0.0003 0.0000 0.0000 0.0017 biochemistry_AlanineAminotransferase_v2 19:43026225:A:AGCCT 19 43026225 AGCCT A 0.00215829 0.879949 36.9704 1.2E-09 0.131277 22.6 CEACAM1 frameshift lost 19:43026222:G:T 1.0 36.9704 1.0 0.131277 0.0 19:43026222:G:T 36.9704 1.0 N/A N/A N/A N/A N/A biochemistry_AlanineAminotransferase_v2 1:220101499:G:A 1 220101499 A G 0.00118262 0.883767 91.6082 1.1E-21 0.294523 28.7 SLC30A10 missense won rs12044156 0.000440397463951 99.0953 0.00040712343529 -0.0199399 87.8036289575 rs12044156 99.0953 0.00040712343529 SLC30A10 0.0009 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 2:21228891:CA:C 2 21228891 C CA 0.00014714 0.642863 31.9647 1.6E-08 0.583553 25.3 APOB frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_AlanineAminotransferase_v2 7:87060844:C:T 7 87060844 T C 0.00842123 0.959777 51.4327 7.4E-13 0.0803947 32 ABCB4 missense lost 7:87021439_CT_C 0.912127030482 51.9658 0.902769820164 -0.0866245 0.103904097204 rs368556713 160.023 0.00241478874025 ABCB4 0.0021 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:22885843:C:T 8 22885843 T C 0.000856841 0.84979 41.1373 1.4E-10 -0.241912 22.6 TNFRSF10B splice_donor won N/A N/A N/A N/A N/A N/A N/A N/A N/A TNFRSF10B 0.0001 0.0000 0.1188 0.9908 biochemistry_AlanineAminotransferase_v2 8:144803586:G:A 8 144803586 A G 0.00889792 0.815952 32.1961 1.4E-08 -0.0664378 LOW NONE N/A lost 8:144799791:T:C 0.987219711091 32.5508 0.976462161921 -0.0679364 0.00132316260831 8:145731636:T:G 595.409 0.015659769321 MAPK15 0.0002 0.0033 0.0229 0.5339 biochemistry_AlanineAminotransferase_v2 8:144991613:G:A 8 144991613 A G 0.0002123 0.711019 286.294 3.2E-64 -1.39765 28.3 PLEC missense lost 8:145730000:C:T 0.851189282049 468.42 0.520239068176 -1.48369 1.7151541413 8:145730000:C:T 468.42 0.520239068176 PLEC 0.0009 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:144997604:C:T 8 144997604 T C 0.000143982 0.703778 62.8096 2.3E-15 -0.813046 22.4 PLEC missense lost 8:145730161:C:T 0.875512611566 278.945 0.197137776004 -1.39936 0.259780103716 8:145730161:C:T 278.945 0.197137776004 PLEC 0.0000 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145024570:C:T 8 145024570 T C 0.000558229 0.942671 427.279 6.4E-95 -0.913636 28.5 PLEC missense lost rs191616586 0.85939546837 1655.5 0.221807089296 1.22788 2.2747338793 8:145732114:G:C 2324.53 0.148759861636 PLEC 0.0000 0.0000 0.0001 0.0000 biochemistry_AlanineAminotransferase_v2 8:145095539:AC:A 8 145095539 A AC 4.90557e-05 0.610338 89.9993 2.4E-21 -1.70111 23.6 SPATC1 frameshift lost rs573543682 0.504845464888 935.393 0.048573956025 1.62295 7.54157254289 8:145732114:G:C 2324.53 0.017301719296 N/A N/A N/A N/A N/A biochemistry_AlanineAminotransferase_v2 8:145559746:C:T 8 145559746 T C 0.000930123 0.867763 37.7603 8.0E-10 -0.209217 20.6 SCRT1 missense lost rs112881267 0.988280556226 604.543 0.061728893209 0.270938 0.0013042040563 8:145730221:G:A 744.613 0.049296432784 SCRT1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145638286:C:T 8 145638286 T C 0.000863503 0.7821 77.02 1.7E-18 -0.332282 24.7 SLC39A4 missense lost rs752209725 0.977247366862 111.357 0.675912535321 0.439146 0.010083010491 8:145730221:G:A 744.613 0.047238849025 SLC39A4 0.0009 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145639654:T:C 8 145639654 C T 0.00269492 0.792763 77.0361 1.7E-18 -0.191513 20.1 SLC39A4 missense lost 8:145626533:C:T 0.853604514603 119.639 0.549639856129 -0.255216 0.446047814952 8:146007003_CAT_C 416.297 0.00079722087201 SLC39A4 0.0000 0.0000 0.0226 0.0000 biochemistry_AlanineAminotransferase_v2 8:145650192:G:A 8 145650192 A G 5.82343e-05 0.610652 36.5031 1.5E-09 -1.0711 26.1 VPS28 missense lost 8:145729821:C:A 0.343227963591 38.9805 0.321414160356 -2.03645 6.26082007913 8:145732114:G:C 2324.53 0.00187482072064 VPS28 0.0000 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145729793:G:A 8 145729793 A G 0.0002948 0.808642 403.882 7.9E-90 -1.28883 24.7 GPT missense lost rs571361563 1.02360427454 426.196 0.970012251664 1.30589 0.0556025875022 rs571361563 426.196 0.970012251664 GPT 0.0007 0.0000 0.0068 0.0000 biochemistry_AlanineAminotransferase_v2 8:145729821:C:A 8 145729821 A C 1.40524e-05 0.726258 38.9805 4.3E-10 -2.03645 27.8 GPT missense won 8:145732071:A:G 0.000262438014202 76.7381 0.000133310116 -0.0328765 37.7277665433 8:145732071:A:G 76.7381 0.000133310116 GPT 0.0001 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730000:C:T 8 145730000 T C 0.000381551 0.559607 468.42 7.1E-104 -1.48369 29.7 GPT missense won N/A N/A N/A N/A N/A N/A rs782338776 328.488 0.538824998209 GPT 0.0034 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730017:C:T 8 145730017 T C 0.000151526 0.667343 350.055 4.1E-78 -1.81599 27.7 GPT missense won N/A N/A N/A N/A N/A N/A rs1735176 201.36 0.000138933369 GPT 0.0021 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730018:G:A 8 145730018 A G 0.000601023 0.854987 41.6356 1.1E-10 -0.272554 23.1 GPT missense lost rs568885042 1.14525669974 53.5692 0.890128093156 0.295321 0.204987108347 8:145756170:G:A 246.216 0.00071815960225 GPT 0.0018 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730071:C:T 8 145730071 T C 7.85177e-05 0.524952 201.103 1.2E-45 -2.19985 32 GPT missense won N/A N/A N/A N/A N/A N/A rs74401356 117.646 0.00014085179761 GPT 0.0002 0.0000 0.0006 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730161:C:T 8 145730161 T C 0.000234384 0.597529 278.945 1.3E-62 -1.39936 24.8 GPT missense won N/A N/A N/A N/A N/A N/A 8:145738581_TGG_T 232.981 0.000125955729 GPT 0.0000 0.0000 0.0001 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730243:G:A 8 145730243 A G 9.10784e-05 0.539471 109.715 1.1E-25 -1.46014 LOW NONE N/A won N/A N/A N/A N/A N/A N/A 8:144994149:G:A 86.2376 0.700388219664 GPT 0.0005 0.0000 0.5692 0.2881 biochemistry_AlanineAminotransferase_v2 8:145730251:G:A 8 145730251 A G 2.16049e-05 0.88927 64.7531 8.5E-16 -1.89304 27.0 GPT missense won rs2955226 0.000325445147272 135.904 0.00015506226576 0.0379518 62.4378690016 rs2955226 135.904 0.00015506226576 GPT 0.0056 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730717:C:T 8 145730717 T C 4.26499e-05 0.850034 54.3189 1.7E-13 -1.18702 21.3 GPT missense won N/A N/A N/A N/A N/A N/A rs752771299 52.6189 0.8857068544 GPT 0.0057 0.0000 0.0012 0.0000 biochemistry_AlanineAminotransferase_v2 8:145730775:G:A 8 145730775 A G 3.56797e-05 0.641837 74.4402 6.3E-18 -1.80733 37 GPT stop_gained won 8:145684019:T:C 0.000526923777836 88.0804 0.00044532394729 -0.0458057 71.061901474 8:145684019:T:C 88.0804 0.00044532394729 GPT 0.0014 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145731252:G:T 8 145731252 T G 2.30832e-05 0.626776 40.4576 2.0E-10 -1.71072 23.6 GPT missense won rs11993550 0.000773936261813 192.326 0.00016280484025 0.284494 38.237874209 rs11993550 192.326 0.00016280484025 GPT 0.0146 0.0015 0.0002 0.0000 biochemistry_AlanineAminotransferase_v2 8:145731376:A:G 8 145731376 G A 2.49825e-05 0.939212 99.1442 2.3E-23 -2.05701 29.4 GPT splice_acceptor won N/A N/A N/A N/A N/A N/A 8:145741379:C:T 94.2726 1.0 GPT 0.3054 0.9471 0.0207 0.0000 biochemistry_AlanineAminotransferase_v2 8:145731707:C:T 8 145731707 T C 2.71148e-05 0.554926 45.6725 1.4E-11 -1.77907 25.0 GPT missense lost 8:145693080:C:G 1.05267502326 48.0783 1.0 -1.76314 0.0308734795422 8:146227402_ATG_A 74.7462 0.00012770808064 GPT 0.0005 0.0000 0.0006 0.0000 biochemistry_AlanineAminotransferase_v2 8:145732034:G:A 8 145732034 A G 4.13956e-05 0.812053 78.8361 6.7E-19 -1.47462 24.9 GPT missense won N/A N/A N/A N/A N/A N/A 8:143854029:A:G 51.5478 0.00016443445824 GPT 0.0023 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145732114:G:C 8 145732114 C G 0.00157231 0.669999 2324.53 2.8E-507 -1.47737 24.2 GPT missense won N/A N/A N/A N/A N/A N/A 8:145732180:G:C 2324.53 1.0 GPT 0.9356 0.0039 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145732151:G:A 8 145732151 A G 0.00256713 0.722811 293.288 9.6E-66 -0.402536 23.9 GPT missense won N/A N/A N/A N/A N/A N/A rs566637055 190.493 0.00014581045504 GPT 0.0036 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145732177:G:A 8 145732177 A G 0.000106188 0.884692 229.945 6.1E-52 -1.59148 24.6 GPT missense lost 8:145640684:G:A 0.966206863254 234.026 0.9493579225 -1.68016 0.0667811439149 rs2467663 247.294 0.00018429691536 GPT 0.0000 0.0000 0.0062 0.0023 biochemistry_AlanineAminotransferase_v2 8:145732180:G:C 8 145732180 C G 0.00157231 0.669999 2324.53 2.8E-507 -1.47737 23.4 GPT missense lost 8:145732114:G:C 1.0 2324.53 1.0 -1.47737 0.0 8:145732114:G:C 2324.53 1.0 GPT 0.0017 0.0000 0.0000 0.0000 biochemistry_AlanineAminotransferase_v2 8:145732225:C:T 8 145732225 T C 7.65557e-05 0.692162 219.624 1.1E-49 -2.03413 30 GPT missense won N/A N/A N/A N/A N/A N/A 8:145154202:C:T 213.805 0.680408867161 GPT 0.0000 0.0000 0.0005 0.0004 biochemistry_AlanineAminotransferase_v2 8:145741379:C:T 8 145741379 T C 2.37685e-05 0.945514 94.2726 2.7E-22 -2.04199 24.1 RECQL4 missense lost 8:145731376:A:G 1.05167567246 99.1442 1.0 -2.05701 0.061360366976 8:145731376:A:G 99.1442 1.0 RECQL4 0.0007 0.0000 0.0000 0.0002 biochemistry_AlanineAminotransferase_v2 8:145742799:T:C 8 145742799 C T 0.00715731 0.91672 50.1311 1.4E-12 0.0887972 24.3 RECQL4 missense lost rs181450148 0.718142714145 94.6571 0.380333690944 -0.0836111 1.16688582592 rs62531546 338.85 0.00010224849924 RECQL4 0.0000 0.0000 0.0009 0.4227 biochemistry_AlanineAminotransferase_v2 8:145771154:C:T 8 145771154 T C 0.00271775 0.958041 253.554 4.4E-57 -0.321461 26.9 ARHGAP39 missense lost rs138435535 0.952755598979 257.027 0.939881775625 0.309291 0.144929515155 8:146190447_TTAAA_T 577.413 0.00110453863716 ARHGAP39 0.0008 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Albumin_v2 11:116701354:G:A 11 116701354 A G 0.00223628 0.92045 30.0723 4.2E-08 0.124488 31 APOC3 splice_donor lost rs201224580 0.016216872546 36.562 0.013338402064 -0.0189418 22.9008354001 11:118955679:C:T 150.915 0.00010141497025 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_Albumin_v2 12:111885310:G:A 12 111885310 A G 0.00200043 0.885884 36.6207 1.4E-09 -0.151953 32 SH2B3 missense lost rs537602334 1.0227598807 42.9831 0.871369974784 0.160354 0.00468927846975 rs648997 102.63 0.00052094867049 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_Albumin_v2 14:94847386:G:A 14 94847386 A G 0.00426716 0.970109 164.228 1.3E-37 0.204912 23.1 SERPINA1 missense won 14:94795492:A:G 0.0563352289368 577.044 0.016033130884 0.0631308 95.5206475395 rs926144 577.513 0.015535877449 SERPINA1 0.0004 0.0000 0.0301 0.0000 biochemistry_Albumin_v2 15:75982492:G:A 15 75982492 A G 0.00905912 0.905358 39.1402 3.9E-10 0.0703928 23.8 CSPG4 missense lost rs149978667 0.997059038291 78.021 0.500187003121 -0.0841412 8.47580812515e-05 rs872926 193.018 0.00190466780625 CSPG4 0.0000 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 15:75982513:A:G 15 75982513 G A 0.00932656 0.898396 37.4816 9.2E-10 0.0678143 24.0 CSPG4 missense lost 15:75985469:A:C 1.00011319095 42.268 0.886861043289 0.0735483 1.20048552217e-07 rs872926 193.018 0.001821240976 CSPG4 0.0000 0.0000 0.0001 0.0000 biochemistry_Albumin_v2 15:75982581:G:C 15 75982581 C G 0.0097539 0.945429 44.5047 2.5E-11 0.0716033 24.0 CSPG4 missense lost rs137915737 0.99962395125 53.1078 0.837691715025 -0.0801944 1.57367793088e-06 rs872926 193.018 0.00215228261329 CSPG4 0.0003 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 15:75985469:A:C 15 75985469 C A 0.00904445 0.905292 42.268 8.0E-11 0.0735483 24.8 CSPG4 missense lost rs112340620 1.00048609256 52.895 0.799480974769 -0.073341 2.49622727535e-06 rs872926 193.018 0.00190801228864 CSPG4 0.0001 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 17:16852187:A:G 17 16852187 G A 0.00697773 0.947032 104.739 1.4E-24 0.135506 26.1 TNFRSF13B missense won rs12603708 0.0013046733098 109.716 0.00124548997225 0.029582 97.3092499843 17:16842991:G:A 141.938 0.00066307280004 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 19:36332622:C:T 19 36332622 T C 0.000428384 0.743542 44.1391 3.1E-11 -0.383801 27.5 NPHS1 missense won rs560301301 0.00186368215769 70.6432 0.00116446102564 0.0417705 40.410357355 19:35543438_CA_C 175.289 0.00023769313929 NPHS1 0.0017 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 19:49994333:G:A 19 49994333 A G 0.000617576 0.937141 32.5133 1.2E-08 0.251367 21.7 RPL13A missense lost rs186008471 0.721313213421 56.0827 0.418173035569 -0.409613 0.738377262745 rs36013629 923.244 0.00021202563321 RPL13A 0.0089 0.0000 0.0001 0.0001 biochemistry_Albumin_v2 19:50017217:G:A 19 50017217 A G 1.84961e-05 0.500692 59.2235 1.4E-14 -2.73429 25.7 FCGRT missense won N/A N/A N/A N/A N/A N/A rs117979630 47.0796 0.00023271197401 FCGRT 0.0117 0.0000 0.0002 0.0000 biochemistry_Albumin_v2 19:50017538:G:C 19 50017538 C G 0.00819464 0.955029 799.714 6.2E-176 -0.341064 22.6 FCGRT missense won N/A N/A N/A N/A N/A N/A 19:50016759:C:T 657.017 0.00093968610849 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_Albumin_v2 19:50154190:G:A 19 50154190 A G 0.00540673 0.95981 58.2877 2.3E-14 -0.109005 23.2 SCAF1 missense lost rs187882126 1.07766452775 93.8933 0.668999669776 0.113887 0.0846386447429 19:50016759:C:T 657.017 0.00054076711936 SCAF1 0.0001 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 1:220101499:G:A 1 220101499 A G 0.00117624 0.883767 31.4402 2.1E-08 -0.179921 28.7 SLC30A10 missense lost 1:219748784:G:T 0.00314725946587 53.415 0.00185248464025 -0.0218803 28.0115323049 rs749853052 115.196 0.00052777710756 SLC30A10 0.0009 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 20:43048414:G:A 20 43048414 A G 0.000743454 0.914917 41.1832 1.4E-10 -0.262094 27.4 HNF4A missense won 20:43950529_AAAAC_A 0.00162142190016 55.9057 0.00119442816025 0.020302 37.9333371161 rs67068737 56.5374 0.00114925746049 HNF4A 0.0013 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 4:73178070:C:T 4 73178070 T C 3.2268e-05 0.837615 60.9389 5.9E-15 -1.58263 26.4 ADAMTS3 missense lost rs187918276 1.04878908527 610.622 0.104667131529 1.60495 0.035405790771 rs187918276 610.622 0.104667131529 ADAMTS3 0.0000 0.0000 0.0001 0.0000 biochemistry_Albumin_v2 4:74270111:C:T 4 74270111 T C 8.69347e-05 0.708277 30.5155 3.3E-08 -0.749253 31 ALB missense lost 4:74091578_CAAAAAAAAAAAAAAA_C 0.000237361111418 46.6523 0.00015525907609 0.0258874 29.5824673699 4:74091578_CAAAAAAAAAAAAAAA_C 46.6523 0.00015525907609 ALB 0.0000 0.0000 0.0024 0.0563 biochemistry_Albumin_v2 4:74272435:CAT:C 4 74272435 C CAT 5.54297e-05 0.577907 97.0866 6.6E-23 -1.82685 32 ALB frameshift won N/A N/A N/A N/A N/A N/A rs3756069 59.0776 0.077855508676 N/A N/A N/A N/A N/A biochemistry_Albumin_v2 4:74274363:A:G 4 74274363 G A 0.000776382 0.878554 40.9737 1.5E-10 -0.2603 24.7 ALB missense won rs144908584 0.000365279113917 50.7981 0.00029463379201 0.0455202 39.4224654676 rs144908584 50.7981 0.00029463379201 ALB 0.0000 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 4:74285240:G:A 4 74285240 A G 0.000520351 0.925365 32.6905 1.1E-08 -0.272194 20.3 ALB missense won rs6829551 0.00144830670008 33.2415 0.00142430005201 0.0143839 30.2496656765 rs9995176 53.2007 0.00053660795904 ALB 0.0001 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 5:75866423:C:T 5 75866423 T C 0.000676595 0.910187 29.9229 4.5E-08 -0.226575 41 IQGAP2 stop_gained lost rs250722 0.00361552729704 45.4477 0.00238047385801 -0.0180152 26.4326036978 5:76124326_TA_T 80.7992 0.00023442059664 IQGAP2 0.0904 0.0000 0.0000 0.0000 biochemistry_Albumin_v2 7:2296552:A:G 7 2296552 G A 0.00376625 0.988495 189.875 3.4E-43 -0.236247 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs77523736 148.947 0.754915961881 SNX8 0.0000 0.0000 0.0000 0.0001 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_AlkalinePhosphatase_v2 10:103988298:T:A 10 103988298 A T 0.00256057 0.936509 35.2307 2.9E-09 -0.103091 25.6 ELOVL3 missense lost rs189363867 0.79513163884 54.1167 0.517641397729 0.0924221 0.413205243037 rs74501283 546.659 0.033464482489 ELOVL3 0.0104 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 10:105139477:G:A 10 105139477 A G 0.00879118 0.946584 71.3502 3.0E-17 -0.0867867 20.7 TAF5 missense lost rs189169856 0.992300755822 76.9421 0.920183584644 0.0977581 0.00106147093656 rs74501283 546.659 0.045639913225 TAF5 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 12:655811:G:T 12 655811 T G 0.000415755 0.849416 35.3463 2.8E-09 0.272609 27.0 B4GALNT3 splice_acceptor lost rs541748039 1.01826849448 38.2515 0.940931040256 -0.29657 0.0029224657826 12:570840:A:G 1021.1 0.00014299615561 B4GALNT3 0.8800 0.9729 0.0000 0.0001 biochemistry_AlkalinePhosphatase_v2 12:665822:C:T 12 665822 T C 0.000504559 0.875525 51.1421 8.6E-13 0.300358 27.7 B4GALNT3 missense won rs766955292 0.00514673347328 172.028 0.00153006927921 -0.0358818 44.0673707753 12:570840:A:G 1021.1 0.00025170139801 B4GALNT3 0.0001 0.0000 0.0016 0.0000 biochemistry_AlkalinePhosphatase_v2 12:667217:G:A 12 667217 A G 0.000382825 0.765201 43.7381 3.8E-11 0.332113 32 B4GALNT3 missense won 12:570840:A:G 0.00235361999817 1021.1 0.00010081565649 -0.0587046 39.5972118597 12:570840:A:G 1021.1 0.00010081565649 B4GALNT3 0.0008 0.0015 0.0036 0.0000 biochemistry_AlkalinePhosphatase_v2 12:100926308:T:C 12 100926308 C T 0.0063135 0.95263 39.4949 3.3E-10 -0.0729961 25.9 NR1H4 missense won rs11837065 0.0106466923274 42.7665 0.00983222963776 0.0128691 31.7650005051 rs61941785 47.1217 0.00033274502569 NR1H4 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 12:109661672:A:G 12 109661672 G A 0.00198458 0.775439 110.331 8.3E-26 -0.242687 24.1 ACACB missense won rs2013002 0.000403647543437 134.69 0.00033064694569 0.0211858 105.942218645 rs2013002 134.69 0.00033064694569 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 16:2139814:G:A 16 2139814 A G 0.00409962 0.927334 33.0027 9.2E-09 -0.0946804 25.4 PKD1 missense lost rs533373091 1.00602394698 45.0635 0.736771589316 0.0985739 0.000298501572985 rs9926191 213.637 0.051278696704 PKD1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 16:2158419:G:A 16 2158419 A G 0.00400765 0.835764 80.6916 2.6E-19 -0.13806 23.8 PKD1 missense won rs9926191 0.0937192684208 213.637 0.035398164736 0.0512087 38.8487456799 rs9926191 213.637 0.035398164736 PKD1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 16:11785220:G:A 16 11785220 A G 0.00236169 0.866328 32.787 1.0E-08 0.100623 24.4 TXNDC11 missense lost rs10492850 0.00942779528273 91.6483 0.00337277531536 -0.0173434 26.7290812941 rs933574 134.283 0.00198110449216 TXNDC11 0.0000 0.0000 0.0200 0.0000 biochemistry_AlkalinePhosphatase_v2 16:55903640:G:A 16 55903640 A G 0.0093177 0.957717 32.5416 1.2E-08 0.0559191 23.7 CES5A missense lost 16:55857570:C:T 1.17203666455 119.519 0.31911201 0.0839959 0.222058051008 16:55857570:C:T 119.519 0.31911201 CES5A 0.0082 0.0001 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 16:83992895:A:G 16 83992895 G A 0.00373909 0.920096 56.896 4.6E-14 -0.112793 24.8 OSGIN1 missense won rs4782860 0.0237139371395 136.348 0.009895474576 0.0250681 40.7220223173 rs4782568 208.438 0.00324618481009 OSGIN1 0.0000 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 16:83994249:C:G 16 83994249 G C 0.00288371 0.922815 42.221 8.2E-11 -0.116639 23.9 OSGIN1 missense lost rs182906393 0.584973525612 46.4658 0.531534316096 0.156882 2.33491780131 rs4782568 208.438 0.00101180611921 OSGIN1 0.7155 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 16:83999565:G:A 16 83999565 A G 0.00661193 0.926661 56.5127 5.6E-14 -0.0925371 24.8 OSGIN1 missense won rs4782568 0.0156394307804 208.438 0.00424023671241 0.0259299 43.2618287867 rs4782568 208.438 0.00424023671241 OSGIN1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 17:6546295:T:G 17 6546295 G T 5.38187e-05 0.756311 56.6007 5.3E-14 1.13393 29.4 TXNDC17 missense lost 17:7343219:C:T 0.587582812149 245.2 0.135634577796 1.21844 3.08495339688 17:7080255:CCCCCAGCCCCAG:C 12848.3 0.00179786176144 TXNDC17 0.0000 0.1614 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077029:C:A 17 7077029 A C 8.49528e-05 0.933345 120.568 4.8E-28 1.16035 29.7 ASGR1 missense won rs372132432 0.00169702509754 1266.59 0.00016154155801 0.0721096 110.83901797 rs372132432 1266.59 0.00016154155801 ASGR1 0.0001 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077063:C:G 17 7077063 G C 0.000228498 0.876384 366.961 8.6E-82 1.19909 26.2 ASGR1 missense lost 17:7160171:TC:T 0.986106556175 368.289 0.982550790169 1.2158 0.0178325110535 rs139295128 856.092 0.00024502893156 ASGR1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077097:C:T 17 7077097 T C 2.79146e-05 0.838847 78.9485 6.4E-19 1.60937 26.5 ASGR1 missense won rs567515569 0.000504137194092 290.89 0.00013682448784 -0.596627 75.4430395867 rs567515569 290.89 0.00013682448784 ASGR1 0.0001 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077122:C:T 17 7077122 T C 4.11062e-05 0.867567 69.7791 6.6E-17 1.26962 37 ASGR1 stop_gained won N/A N/A N/A N/A N/A N/A 17:7329379:G:A 41.1341 0.00033493758169 ASGR1 0.0234 0.0105 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077720:A:C 17 7077720 C A 8.11825e-05 0.554987 121.162 3.5E-28 1.50879 25.8 ASGR1 missense won rs142122735 0.00186391739725 1895.63 0.00011913504201 -0.0843184 110.925955336 rs142122735 1895.63 0.00011913504201 ASGR1 0.0006 0.0000 0.0014 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7077721:G:C 17 7077721 C G 8.11825e-05 0.554987 121.162 3.5E-28 1.50879 25.1 ASGR1 missense lost 17:7077720:A:C 1.0 121.162 1.0 1.50879 0.0 rs142122735 1895.63 0.00011913504201 ASGR1 0.0002 0.0000 0.0032 0.0002 biochemistry_AlkalinePhosphatase_v2 17:7077781:T:C 17 7077781 C T 9.33442e-05 0.79244 82.7666 9.2E-20 0.923133 32 ASGR1 splice_acceptor won rs1961524 0.00154950880316 391.568 0.00032752312576 -0.0451632 76.3788316863 rs7406466 581.976 0.00014350602436 ASGR1 0.9704 0.9971 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7080300:C:A 17 7080300 A C 2.01994e-05 0.555016 36.421 1.6E-09 1.69116 38 ASGR1 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A ASGR1 0.0000 0.0000 0.1082 0.5032 biochemistry_AlkalinePhosphatase_v2 17:7126161:A:G 17 7126161 G A 2.62623e-05 0.827316 33.698 6.4E-09 1.09295 23.5 ACADVL missense lost 17:7106378:G:A 0.956713761348 8371.93 0.00385088508025 1.13146 0.016136140748 17:7080255:CCCCCAGCCCCAG:C 12848.3 0.00303637367089 ACADVL 0.0068 0.0000 0.1686 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7366212:G:A 17 7366212 A G 4.04256e-05 0.966947 45.517 1.5E-11 0.97667 26.5 ZBTB4 missense lost rs555910710 0.991256646519 705.209 0.063979655364 -1.06426 0.00087372459827 17:7080255:CCCCCAGCCCCAG:C 12848.3 0.00332627874121 ZBTB4 0.0000 0.0000 0.0002 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7699912:G:A 17 7699912 A G 4.1751e-05 0.876386 60.0614 9.2E-15 1.07336 23.0 DNAH2 missense lost 17:7080255:CCCCCAGCCCCAG:C 0.827321995562 12848.3 0.00386744684544 1.2448 0.491130860533 17:7080255:CCCCCAGCCCCAG:C 12848.3 0.00386744684544 DNAH2 0.0000 0.0000 0.0101 0.0000 biochemistry_AlkalinePhosphatase_v2 17:7980420:G:A 17 7980420 A G 0.00012948 0.748834 78.2578 9.0E-19 0.803184 24.4 ALOX12B missense lost 17:7384753:C:T 0.753205341899 170.819 0.345068130625 1.22004 1.36616757814 17:7080255:CCCCCAGCCCCAG:C 12848.3 0.00413103138361 ALOX12B 0.0035 0.0000 0.0022 0.0000 biochemistry_AlkalinePhosphatase_v2 18:60052034:A:G 18 60052034 G A 0.00106613 0.982214 39.8049 2.8E-10 -0.169187 25.5 TNFRSF11A missense won rs755339403 0.00775407138465 169.209 0.00182407576464 0.0253837 33.1033335429 rs2957137 338.815 0.00065363569569 TNFRSF11A 0.0047 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 19:41349774:A:G 19 41349774 G A 0.00171472 0.898556 43.9588 3.4E-11 0.1589 22.6 CYP2A6 missense lost rs116921376 0.691985315217 52.7419 0.5767491136 -0.15672 1.24281289529 rs56113850 655.007 0.00043204948164 CYP2A6 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 19:49206818:G:A 19 49206818 A G 0.00521766 0.725584 34.6728 3.9E-09 -0.080156 24.5 FUT2 missense lost rs183363666 0.825770043985 46.2266 0.619378444036 0.0763942 0.288902047326 rs679574 4426.6 0.00353392203024 FUT2 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 19:50017538:G:C 19 50017538 C G 0.00820343 0.955029 61.3253 4.8E-15 0.0779493 22.6 FCGRT missense won 19:49129486:G:A 0.00164545497122 328.395 0.00030727635849 0.0644973 56.4509835692 rs12462337 487.952 0.00014334793984 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_AlkalinePhosphatase_v2 19:50154190:G:A 19 50154190 A G 0.00540163 0.95981 31.4748 2.0E-08 0.0690774 23.2 SCAF1 missense lost rs187882126 0.907500415604 42.4338 0.673128357136 -0.068102 0.0706323156351 rs2548457 688.623 0.00012947253796 SCAF1 0.0001 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:19983572:G:T 1 19983572 T G 0.000322894 0.777181 60.6984 6.7E-15 -0.428624 39 MINOS1-NBL1 stop_gained lost 1:21890587:G:A 0.705871024702 834.851 0.051320824681 -1.50228 1.55074744105 1:21890587:G:A 834.851 0.051320824681 NBL1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:20442878:C:T 1 20442878 T C 0.00801172 0.912971 29.9804 4.4E-08 -0.0508815 24.1 PLA2G2D missense lost rs529876271 0.976631566234 1473.61 0.019869439681 0.594869 0.00414148494928 1:21889760:G:A 9714.88 0.00162318740544 PLA2G2D 0.0254 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:20960099:C:G 1 20960099 G C 6.48744e-05 0.542377 71.6918 2.5E-17 -1.19704 24.6 PINK1 missense lost rs140726985 0.312263722448 3567.51 0.006275174656 0.764242 13.9549866481 1:21889760:G:A 9714.88 0.00229152732601 PINK1 0.0000 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21031200:C:T 1 21031200 T C 6.36609e-05 0.562066 33.4091 7.5E-09 -0.842602 33 KIF17 missense lost rs529876271 0.415247064951 1473.61 0.00941431635076 0.594869 4.22470531626 1:21889760:G:A 9714.88 0.00046186737921 KIF17 0.0012 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21044007:C:T 1 21044007 T C 0.00629473 0.921813 36.0533 1.9E-09 0.0634913 23.4 KIF17 missense lost rs7555005 0.277831037717 3223.56 0.00310734894096 -0.114834 8.06286755481 rs72659199 3748.04 0.00017755029504 KIF17 0.0000 0.0000 0.0000 0.0011 biochemistry_AlkalinePhosphatase_v2 1:21054033:G:A 1 21054033 A G 9.62459e-05 0.917405 60.6233 6.9E-15 -0.759977 38 SH2D5 stop_gained lost 1:21889760:G:A 0.757673739824 9714.88 0.004728075121 -0.755555 1.0175385004 1:21889760:G:A 9714.88 0.004728075121 SH2D5 0.0000 0.0000 0.0008 0.1594 biochemistry_AlkalinePhosphatase_v2 1:21212813:T:C 1 21212813 C T 1.69261e-05 0.677386 30.2774 3.7E-08 -1.41019 27.3 EIF4G3 missense lost 1:21889705:A:C 0.242748317095 2202.42 0.003337141824 -2.1021 7.79214353253 1:21889705:A:C 2202.42 0.003337141824 EIF4G3 0.0005 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21887163:A:C 1 21887163 C A 2.10636e-05 0.913769 132.017 1.5E-30 -2.41099 24.0 ALPL missense won 1:21807405:T:A 0.00165425093657 438.109 0.00049848153289 -0.114151 121.496470664 rs72657183 1099.96 0.0001907161 ALPL 0.0014 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21887620:G:C 1 21887620 C G 3.59702e-05 0.903138 229.947 6.1E-52 -2.34962 28.5 ALPL missense won 1:21932625:G:A 0.0020335708975 1607.47 0.00029090031364 -0.113727 209.675633057 1:21932625:G:A 1607.47 0.00029090031364 ALPL 0.1440 0.0000 0.0003 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21887635:A:G 1 21887635 G A 4.3475e-05 0.8695 317.352 5.5E-71 -2.63963 26.4 ALPL missense won rs6671920 0.00129768016366 1216.14 0.00033862992361 0.0979457 294.89967099 rs10917025 1455.42 0.00013523596681 ALPL 0.0509 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21887660:G:C 1 21887660 C G 2.3204e-05 0.858782 51.7042 6.5E-13 -1.38523 22.9 ALPL missense won rs760863889 0.00708154054879 865.732 0.00042293156409 1.40111 43.3683331126 rs760863889 865.732 0.00042293156409 ALPL 0.0034 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21887691:G:A 1 21887691 A G 1.48081e-05 0.6097 43.0036 5.5E-11 -1.58707 25.5 ALPL missense won rs183304828 0.00375348905924 261.591 0.00061704547216 0.231103 37.8957200793 rs78566499 513.91 0.00014506998025 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889608:C:A 1 21889608 A C 2.32308e-05 0.97167 123.414 1.1E-28 -2.08093 42 ALPL stop_gained won rs150211890 0.0161423839619 2990.77 0.00066611480464 0.257161 94.0460368219 rs145377039 3330.07 0.00033227821225 ALPL 0.0570 0.0003 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889651:G:A 1 21889651 A G 2.2192e-05 0.901695 174.903 6.3E-40 -2.63461 27.1 ALPL missense won rs12023600 0.000802141492771 926.193 0.00015147701776 0.0882012 165.136055549 rs56247965 932.008 0.00015011885529 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889655:A:G 1 21889655 G A 2.75519e-05 0.888265 61.1164 5.4E-15 -1.39828 26.3 ALPL missense won rs1067237 0.00143240027876 866.432 0.00010103868324 0.0594905 56.577790503 rs1067237 866.432 0.00010103868324 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889705:A:C 1 21889705 C A 0.000442711 0.902849 2202.42 9.6E-481 -2.1021 20.7 ALPL missense won rs199787255 0.000996490885093 2631.28 0.00083407750416 0.0983662 2065.566033 rs1976403 4323.22 0.00024605373321 ALPL 0.0003 0.0000 0.0234 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889706:C:A 1 21889706 A C 0.000442711 0.902849 2202.42 9.6E-481 -2.1021 23.3 ALPL missense lost 1:21889705:A:C 1.0 2202.42 1.0 -2.1021 0.0 rs1976403 4323.22 0.00024605373321 ALPL 0.0000 0.0000 0.0072 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889712:G:A 1 21889712 A G 0.000102152 0.746823 347.119 1.8E-77 -1.85552 23.9 ALPL missense won rs1262265 0.00100300372863 2949.48 0.00011804170609 0.114539 325.480481663 rs1262265 2949.48 0.00011804170609 ALPL 0.0005 0.0000 0.0079 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21889741:G:A 1 21889741 A G 0.00030398 0.902797 790.669 5.8E-174 -1.51232 25.7 ALPL missense won rs147704471 0.0014073721683 987.312 0.00112706575524 0.083134 732.457934898 rs1976403 4323.22 0.00017560490256 ALPL 0.0000 0.0000 0.0119 0.0002 biochemistry_AlkalinePhosphatase_v2 1:21889771:G:T 1 21889771 T G 1.76022e-05 0.956713 43.549 4.1E-11 -1.45807 25.7 ALPL missense lost 1:21179980:C:G 0.944709842079 46.6269 0.882348363556 -1.39707 0.0342355121602 rs145377039 3330.07 0.00020013195024 ALPL 0.0000 0.0000 0.3922 0.0002 biochemistry_AlkalinePhosphatase_v2 1:21890587:G:A 1 21890587 A G 0.000416776 0.723251 834.851 1.4E-183 -1.50228 24.7 ALPL missense won rs75141928 0.00036444217393 860.958 0.00035339112169 0.0559387 803.280028253 rs4654942 1140.97 0.00014298180625 ALPL 0.0440 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21890632:G:A 1 21890632 A G 0.000685556 0.939551 1821.56 5.3E-398 -1.48914 25.5 ALPL missense won 1:21902950:C:A 0.00384692912093 2208.41 0.00317305763401 -0.106137 1602.60793102 1:21906604:C:T 4377.58 0.00020327915776 ALPL 0.0005 0.0000 0.0004 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21890636:T:C 1 21890636 C T 0.000303255 0.805878 1075.82 6.0E-236 -1.83016 23.6 ALPL missense won rs12740648 0.00130488650352 1217.78 0.00115277225625 0.0923326 999.499673394 rs1976403 4323.22 0.00013514295001 ALPL 0.0077 0.0000 0.0004 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21890710:G:A 1 21890710 A G 2.34055e-05 0.67521 57.2118 3.9E-14 -1.67547 29.5 ALPL splice_donor won rs76372215 0.00692078776715 2882.02 0.00013738652944 0.177742 48.088705874 rs76372215 2882.02 0.00013738652944 ALPL 0.0001 0.0000 0.1506 0.9546 biochemistry_AlkalinePhosphatase_v2 1:21894598:T:C 1 21894598 C T 2.00785e-05 0.827263 98.1962 3.8E-23 -2.14771 27.3 ALPL missense won rs6671920 0.00124853169648 1216.14 0.00010081164025 0.0979457 91.3793604537 rs6671920 1216.14 0.00010081164025 ALPL 0.0003 0.0032 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21894604:TG:T 1 21894604 T TG 1.13826e-05 0.690088 54.2878 1.7E-13 -2.13883 35 ALPL frameshift won rs149846387 0.0024374618709 55.3184 0.00239205115396 0.120708 49.0596756283 rs116482722 245.172 0.00010875778369 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 1:21894616:G:A 1 21894616 A G 1.42752e-05 0.52556 94.0705 3.0E-22 -3.09709 31 ALPL missense won 1:21889712:G:A 0.0198247627193 347.119 0.00537258214441 -1.85552 69.445090551 1:21889712:G:A 347.119 0.00537258214441 ALPL 0.0017 0.0022 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21894621:T:C 1 21894621 C T 6.44759e-05 0.942351 139.37 3.7E-32 -1.37852 25.6 ALPL missense won 1:21932625:G:A 0.00482479782408 1607.47 0.00041831702784 -0.113727 120.680938538 1:21932625:G:A 1607.47 0.00041831702784 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21894682:C:T 1 21894682 T C 0.000232935 0.849267 301.545 1.5E-67 -1.13552 24.0 ALPL missense won rs1262265 0.00591521355133 2949.48 0.00060475170889 0.114539 256.944794553 rs1976403 4323.22 0.00011053999044 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21894730:C:T 1 21894730 T C 3.40582e-05 0.636116 69.8696 6.3E-17 -1.529 26.0 ALPL missense won rs140726985 0.0608909998226 3567.51 0.00119254880889 0.764242 39.6418426062 1:21889760:G:A 9714.88 0.00042416638209 ALPL 0.0000 0.0000 0.0001 0.0102 biochemistry_AlkalinePhosphatase_v2 1:21896819:C:T 1 21896819 T C 4.7814e-05 0.818699 148.228 4.2E-34 -1.78388 29.8 ALPL missense won rs144999112 0.0136614840386 3698.03 0.00054759276049 0.247037 115.602540128 rs72659199 3748.04 0.00053961431616 ALPL 0.0001 0.0098 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21896823:C:T 1 21896823 T C 0.000411447 0.975292 363.518 4.8E-81 -0.83141 22.6 ALPL missense won rs141344299 0.0780779123181 735.602 0.038584352041 0.239587 188.749236427 1:21906604:C:T 4377.58 0.00018515861329 ALPL 0.0022 0.0000 0.0030 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21900176:A:C 1 21900176 C A 0.000201071 0.921008 1351.3 8.0E-296 -2.40873 27.0 ALPL missense won rs12132412 0.000449292273078 2118.85 0.00028653687076 0.0981734 1294.62142562 rs10799702 3278.22 0.00011137003024 ALPL 0.0027 0.0008 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21900179:T:C 1 21900179 C T 3.65433e-05 0.536108 113.607 1.6E-26 -2.18394 23.6 ALPL missense won 1:21513339_CA_C 0.000302637756635 154.482 0.00022256164225 0.0728758 109.688656392 1:21513339_CA_C 154.482 0.00022256164225 ALPL 0.0002 0.0004 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21900186:C:A 1 21900186 A C 0.000140043 0.848582 607.413 4.1E-134 -1.92859 45 ALPL stop_gained won rs1262265 0.00174901806355 2949.48 0.00036019105369 0.114539 557.669818306 rs1262265 2949.48 0.00036019105369 ALPL 0.0011 0.0017 0.0003 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21900272:GCTT:G 1 21900272 G GCTT 4.12092e-05 0.829438 171.269 3.9E-39 -2.0083 22.6 ALPL inframe_deletion won 1:21944041:G:A 0.00356576208227 653.74 0.00093417032164 -0.136759 151.425389553 rs12118362 1136.9 0.000104346225 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 1:21902389:A:G 1 21902389 G A 4.48183e-05 0.780675 50.4279 1.2E-12 -1.04867 LOW NONE N/A won rs76504298 0.00253519304119 105.093 0.00121648883524 0.0603815 45.4775842813 1:22033228:G:A 782.409 0.00010483507321 ALPL 0.0001 0.0000 0.9828 0.4906 biochemistry_AlkalinePhosphatase_v2 1:21902399:C:T 1 21902399 T C 0.000124949 0.828785 488.339 3.3E-108 -1.88135 28.8 ALPL missense won rs1772722 0.00392179803832 1688.37 0.00113432892804 0.129915 429.090429162 1:21902950:C:A 2208.41 0.000483340225 ALPL 0.0000 0.0000 0.0003 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21903075:A:G 1 21903075 G A 2.27293e-05 0.806824 155.108 1.3E-35 -2.61168 25.7 ALPL missense won rs3767118 0.000773584207866 960.435 0.00012493203529 0.0795911 146.599833047 rs3767118 960.435 0.00012493203529 ALPL 0.0022 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21903929:G:A 1 21903929 A G 6.00428e-05 0.898069 38.9404 4.4E-10 -0.705352 24.3 ALPL missense won rs12740648 0.00735948558355 1217.78 0.00023533094025 0.0923326 32.5457865276 rs12740648 1217.78 0.00023533094025 ALPL 0.0021 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21903941:G:T 1 21903941 T G 3.34134e-05 0.822895 158.692 2.2E-36 -2.13085 23.9 ALPL missense won rs181939530 0.000511459197417 720.036 0.00011272281241 0.0676206 151.595378159 rs181939530 720.036 0.00011272281241 ALPL 0.0040 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21903986:G:A 1 21903986 A G 2.24248e-05 0.86241 41.0018 1.5E-10 -1.22507 23.5 ALPL missense lost rs562438425 0.709024301632 111.48 0.260775678244 1.01747 1.02310504144 rs141878673 272.669 0.004216424356 ALPL 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:21904036:CG:C 1 21904036 C CG 3.70045e-05 0.975879 179.499 6.2E-41 -1.95434 34 ALPL frameshift won 1:22033228:G:A 0.000536724804614 782.409 0.00012313453156 -0.0580194 171.278319334 1:22033228:G:A 782.409 0.00012313453156 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 1:21938584:T:C 1 21938584 C T 0.00350537 0.955722 124.849 5.5E-29 0.184381 21.7 RAP1GAP missense lost 1:21852663_GTC_G 0.69254189771 416.437 0.2076260356 -0.190432 3.51572948394 1:21906604:C:T 4377.58 0.00990359348224 RAP1GAP 0.0000 0.0000 0.0025 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22163436:G:A 1 22163436 A G 0.000601346 0.836236 353.354 7.9E-79 -0.726488 26.7 HSPG2 missense lost 1:21889760:G:A 0.88810383292 9714.88 0.032302513441 -0.755555 1.17264457328 1:21889760:G:A 9714.88 0.032302513441 HSPG2 0.0004 0.0000 0.0005 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22172987:T:C 1 22172987 C T 0.000182654 0.936131 81.1705 2.1E-19 -0.583894 23.9 HSPG2 missense lost 1:21889760:G:A 0.97914010202 9714.88 0.00818098542144 -0.755555 0.00892335372235 1:21889760:G:A 9714.88 0.00818098542144 HSPG2 0.0001 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22172996:G:A 1 22172996 A G 1.93441e-05 0.681061 40.4653 2.0E-10 -1.59088 24.8 HSPG2 missense lost 1:21889760:G:A 0.162665831842 9714.88 0.00067755048804 -0.755555 14.4068115427 1:21889760:G:A 9714.88 0.00067755048804 HSPG2 0.0498 0.0000 0.0057 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22179315:G:A 1 22179315 A G 0.000223635 0.620703 202.491 6.0E-46 -1.05637 25.5 HSPG2 missense won rs140726985 0.365623613139 3567.51 0.020752707364 0.764242 31.6467604224 1:21889760:G:A 9714.88 0.00747132039424 HSPG2 0.0044 0.0000 0.0020 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22188289:G:A 1 22188289 A G 0.00448525 0.87193 1522.1 6.2E-333 -0.545799 29.1 HSPG2 missense lost 1:21889760:G:A 0.975206772382 9714.88 0.152792646769 -0.755555 0.236855714404 1:21889760:G:A 9714.88 0.152792646769 HSPG2 0.0000 0.0000 0.0003 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22206977:C:T 1 22206977 T C 0.00440703 0.907595 66.4768 3.5E-16 -0.0992998 24.0 HSPG2 missense lost 1:21900176:A:C 0.785413698172 1351.3 0.038638192356 -2.40873 0.860363900987 1:21906604:C:T 4377.58 0.00041931571984 HSPG2 0.0005 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 1:22965801:C:A 1 22965801 A C 0.000113808 0.901474 34.9467 3.4E-09 -0.501391 21.5 C1QA missense lost rs748455595 0.989003947277 391.943 0.088182272025 0.676827 0.00106222734321 1:21889760:G:A 9714.88 0.00346262810481 C1QA 0.0000 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 1:23191508:G:A 1 23191508 A G 0.000569791 0.905467 90.5841 1.8E-21 -0.361717 24.7 EPHB2 missense lost rs866029063 1.00392218899 249.174 0.364963390884 0.732836 0.000347695102501 rs10799691 3454.78 0.00012436487361 EPHB2 0.0010 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 20:56136474:C:T 20 56136474 T C 0.00224296 0.940215 71.8032 2.4E-17 0.154709 21.8 PCK1 missense won N/A N/A N/A N/A N/A N/A rs78888165 71.3175 0.035479112881 PCK1 0.0024 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 20:56140439:G:A 20 56140439 A G 0.00257117 0.876177 52.7096 3.9E-13 -0.131094 26.4 PCK1 missense won rs2006027 0.0111217579215 57.6692 0.010165277329 -0.0182118 42.1783414082 rs78888165 71.3175 0.00019716653056 PCK1 0.0859 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 22:46627780:C:T 22 46627780 T C 0.00619871 0.913845 60.8435 6.2E-15 0.0964374 21.5 PPARA missense won N/A N/A N/A N/A N/A N/A rs6008845 48.8813 0.00496664105536 PPARA 0.0000 0.0000 0.0004 0.0000 biochemistry_AlkalinePhosphatase_v2 2:86831051:C:A 2 86831051 A C 0.00746078 0.961929 31.2047 2.3E-08 -0.0572038 25.6 RNF103 missense won N/A N/A N/A N/A N/A N/A rs146000820 29.9105 0.955293166881 RNF103 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 2:169780152:TG:T 2 169780152 T TG 3.87016e-05 0.948516 35.4363 2.6E-09 0.818037 26.9 ABCB11 frameshift won rs72888603 0.000723142647372 244.317 0.00010488627396 -0.0317372 33.556068319 rs72888603 244.317 0.00010488627396 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 2:169847329:T:C 2 169847329 C T 0.000356675 0.855472 60.8999 6.0E-15 0.408413 33 ABCB11 missense won rs7586497 0.00200165972252 254.385 0.00047919836836 -0.0310459 55.5724885477 rs3770586 335.226 0.00030103985025 ABCB11 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 3:70014091:G:A 3 70014091 A G 0.0040955 0.961313 34.9056 3.5E-09 -0.0855076 31 MITF missense won N/A N/A N/A N/A N/A N/A rs560674261 34.1181 0.230558427225 MITF 0.0001 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 3:126070736:G:A 3 126070736 A G 0.000241362 0.92825 35.2459 2.9E-09 0.384075 25.4 KLF15 missense won 3:126268918:G:A 0.000114115528554 36.3065 0.00011078194009 0.0117561 34.4968943672 3:126268918:G:A 36.3065 0.00011078194009 KLF15 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 3:132427031:G:A 3 132427031 A G 0.00703122 0.95706 48.0151 4.2E-12 0.0729717 25.7 NPHP3 missense won rs78341897 0.016101687018 90.0066 0.00858963800809 -0.0240652 36.6027193519 3:132188163:A:G 94.7603 0.00035470825569 NPHP3 0.0005 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 3:155546124:C:T 3 155546124 T C 0.00513507 0.923544 30.6782 3.0E-08 -0.0698778 28.6 SLC33A1 missense lost rs358729 0.00701158666381 30.6906 0.00700875375489 0.00958878 25.7556113538 3:155538173_AT_A 41.2195 0.00329629849956 SLC33A1 0.0002 0.0521 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 3:186338564:C:T 3 186338564 T C 0.00962286 0.939779 41.0954 1.4E-10 -0.0574914 24.0 AHSG missense lost rs149062332 0.857391971561 44.6582 0.788989839001 0.0558192 0.225314458019 rs149062332 44.6582 0.788989839001 AHSG 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 4:110638824:C:T 4 110638824 T C 0.0076995 0.943901 31.4465 2.1E-08 0.0565897 26.2 PLA2G12A missense lost rs189866430 0.991899839332 34.7215 0.898341900481 -0.0658216 0.000517921434821 rs72679249 121.977 0.00157557394225 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24429340:CT:C 6 24429340 C CT 0.00404992 0.97165 3672.01 5.6E-800 -0.864179 26.8 GPLD1 frameshift won rs28709106 0.00217269655984 4048.64 0.00197057863744 -0.123474 3337.667284 rs28709106 4048.64 0.00197057863744 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 6:24436910:A:G 6 24436910 G A 0.00144435 0.980644 673.727 1.5E-148 -0.630051 22.3 GPLD1 missense won 6:24463055:A:G 0.0049117950344 2284.02 0.00144885287044 -0.0906362 582.600973837 rs28709106 4048.64 0.00079573075569 GPLD1 0.0001 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24437509:A:T 6 24437509 T A 0.000547819 0.930508 139.124 4.1E-32 -0.479921 23.8 GPLD1 missense lost rs145033730 0.988983737 164.181 0.838046871601 0.574882 0.00424436524774 rs28709106 4048.64 0.00031572314596 GPLD1 0.0286 0.0000 0.0002 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24446010:C:G 6 24446010 G C 0.000332092 0.914839 119.018 1.0E-27 -0.592925 25.0 GPLD1 missense lost rs771175359 0.982825248169 125.142 0.934729310596 0.63119 0.00885293547502 rs28709106 4048.64 0.00017003638404 GPLD1 0.0000 0.0000 0.0000 0.0001 biochemistry_AlkalinePhosphatase_v2 6:24447202:G:C 6 24447202 C G 0.000239777 0.94704 46.4087 9.6E-12 -0.356079 22.0 GPLD1 missense lost rs190620694 0.9996601996 71.1203 0.652316290921 0.362844 1.33986480311e-06 rs28709106 4048.64 0.000128482225 GPLD1 0.0405 0.0000 0.0002 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24448140:GC:G 6 24448140 G GC 0.000591929 0.883122 525.16 3.2E-116 -0.880309 34 GPLD1 frameshift won rs570617239 0.533081015894 529.683 0.528529 0.743607 38.2490150253 rs28709106 4048.64 0.00027224340004 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 6:24450058:C:T 6 24450058 T C 6.28146e-05 0.862646 37.9482 7.3E-10 -0.727588 26.5 GPLD1 missense lost rs190620694 0.253453512478 71.1203 0.135237120516 0.362844 9.35689441628 6:24480724_GT_G 2643.32 0.00039458246881 GPLD1 0.0000 0.0000 0.0000 0.0007 biochemistry_AlkalinePhosphatase_v2 6:24450108:G:A 6 24450108 A G 0.000680182 0.776743 372.969 4.2E-83 -0.69616 32 GPLD1 missense won rs77818310 0.0141487919731 1497.15 0.00352473753025 0.0965328 289.517709359 rs9358768 3685.82 0.00027381313729 GPLD1 0.0000 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24466972:C:T 6 24466972 T C 6.04414e-05 0.878004 37.7014 8.2E-10 -0.750894 27.4 GPLD1 missense won rs141014144 0.00340652305304 252.28 0.00050907994384 0.0686746 33.4289140795 rs147332462 686.938 0.00014700592516 GPLD1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24467137:T:C 6 24467137 C T 0.000124183 0.810886 62.0438 3.4E-15 -0.694444 LOW NONE N/A won rs185250814 0.0155835628314 290.364 0.00332983240209 0.138983 47.520294465 6:24463020:G:C 2835.75 0.00025608320676 GPLD1 0.0000 0.0000 0.0033 0.5587 biochemistry_AlkalinePhosphatase_v2 6:24472814:G:A 6 24472814 A G 0.000158828 0.862293 85.7827 2.0E-20 -0.700576 27.8 GPLD1 missense won 6:24463020:G:C 0.0257369794525 2835.75 0.00077855508676 -0.147428 60.4666811453 6:24463020:G:C 2835.75 0.00077855508676 GPLD1 0.0000 0.0000 0.0000 0.2100 biochemistry_AlkalinePhosphatase_v2 6:24475394:CCAG:C 6 24475394 C CCAG 4.99409e-05 0.686192 33.4159 7.4E-09 -0.87006 21.0 GPLD1 inframe_deletion lost rs7742675 0.0111919571073 2096.43 0.00017839342096 0.125908 26.7196164247 rs7742675 2096.43 0.00017839342096 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 6:24476431:T:C 6 24476431 C T 0.00285533 0.975159 441.804 4.4E-98 -0.361066 23.9 GPLD1 missense won rs147332462 0.0263137292592 686.938 0.016923668281 0.0719946 310.094976386 rs62400470 3211.25 0.00102343047921 GPLD1 0.0000 0.0001 0.0000 0.0552 biochemistry_AlkalinePhosphatase_v2 6:24476437:C:T 6 24476437 T C 0.00350211 0.985904 456.677 2.5E-101 -0.335312 25.3 GPLD1 missense won rs534566342 0.0326810153561 533.885 0.027954836809 -0.0719337 306.48652482 rs62401885 2021.58 0.00039244402404 GPLD1 0.0001 0.0000 0.0000 0.1041 biochemistry_AlkalinePhosphatase_v2 6:24476438:G:A 6 24476438 A G 7.03373e-05 0.90796 56.6763 5.1E-14 -0.759775 42 GPLD1 stop_gained won 6:24480724_GT_G 0.0285263137724 2643.32 0.00061164214596 0.150367 39.1481125189 6:24463020:G:C 2835.75 0.00047904514641 GPLD1 0.0000 0.0000 0.0000 0.2205 biochemistry_AlkalinePhosphatase_v2 6:24495234:T:G 6 24495234 G T 0.00589918 0.994803 91.775 9.7E-22 0.112146 22.3 ALDH5A1 missense lost 6:24476700:C:T 0.99728503216 539.925 0.169515828729 0.117799 0.000169349504302 rs28709106 4048.64 0.011057784336 ALDH5A1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:24520719:G:A 6 24520719 A G 0.00580394 0.985725 168.877 1.3E-38 -0.157373 26.5 ALDH5A1 missense lost rs189703807 1.08258146356 217.812 0.839361971889 0.167705 0.276614207856 rs28709106 4048.64 0.00327433439524 ALDH5A1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:25594698:G:A 6 25594698 A G 0.00147454 0.964387 34.3423 4.6E-09 -0.131534 23.1 LRRC16A missense lost 6:25594699:A:G 1.00051831124 34.3601 1.0 -0.131531 2.30588746039e-06 rs28709106 4048.64 0.00014852540641 LRRC16A 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 6:25773865:C:A 6 25773865 A C 6.27653e-05 0.81327 43.7631 3.7E-11 -0.792297 23.8 SLC17A4 missense lost rs183821586 0.488707552701 560.149 0.038181550801 0.648788 3.9629729953 6:24436910:A:G 673.727 0.029252629156 SLC17A4 0.0008 0.0000 0.0000 0.0701 biochemistry_AlkalinePhosphatase_v2 6:25773877:C:T 6 25773877 T C 0.000385319 0.960465 110.042 9.6E-26 -0.470662 22.8 SLC17A4 missense lost 6:24687887:GA:G 0.964940815542 497.105 0.213604806276 -0.868413 0.0344205014347 rs772610711 993.034 0.00034088606161 SLC17A4 0.0000 0.0000 0.0000 0.0306 biochemistry_AlkalinePhosphatase_v2 6:31083945:C:T 6 31083945 T C 0.00520385 0.999338 35.0523 3.2E-09 -0.0674729 25.7 CDSN missense lost 6:30997275:C:G 0.971359884272 38.8956 0.875379170689 -0.0672402 0.00729277919689 rs372319444 98.2197 0.00086159273841 PSORS1C1 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 7:127014438:T:C 7 127014438 C T 0.00415342 0.965149 210.471 1.1E-47 -0.200348 22.0 ZNF800 missense won N/A N/A N/A N/A N/A N/A rs565056821 151.91 0.479351291904 ZNF800 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 9:135553973:C:T 9 135553973 T C 0.000344656 0.971828 37.4676 9.3E-10 -0.286012 22.4 GTF3C4 missense lost 9:136138765_GCGCCCACCACTA_G 0.566552419653 20339.0 0.001043677636 0.32794 2.2914768333 rs550057 22668.4 0.00067998906756 GTF3C4 0.0000 0.0000 0.0001 0.0000 biochemistry_AlkalinePhosphatase_v2 9:135946015:T:C 9 135946015 C T 0.00628501 0.840718 55.2125 1.1E-13 -0.0902496 25.6 CEL missense lost 9:136149709_AC_A 0.977739123495 19888.1 0.00271435790025 0.32898 0.00691730123034 rs550057 22668.4 0.00166120641241 CEL 0.0000 0.0000 0.0000 0.0010 biochemistry_AlkalinePhosphatase_v2 9:136029416:C:G 9 136029416 G C 0.000690781 0.969293 66.378 3.7E-16 -0.289366 23.3 GBGT1 missense lost rs568334984 0.887766774593 90.4499 0.651500808336 0.280696 0.221652684928 rs550057 22668.4 0.00180457588809 GBGT1 0.0659 0.0000 0.0018 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136031315:T:C 9 136031315 C T 0.0050689 0.916707 316.348 9.0E-71 -0.235381 25.8 GBGT1 missense lost rs2519093 0.83902890306 20379.6 0.013024059129 0.326079 2.2329376479 rs550057 22668.4 0.00881760438441 GBGT1 0.0265 0.0002 0.0003 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136031323:C:T 9 136031323 T C 0.000166767 0.888376 39.0505 4.1E-10 -0.472939 41 GBGT1 stop_gained lost 9:136155000:C:T 0.333699551138 20121.7 0.00064761597289 -0.323967 6.96523770896 rs550057 22668.4 0.00038590638025 GBGT1 0.0002 0.0923 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136217563:G:A 9 136217563 A G 0.00468006 0.962566 34.6404 4.0E-09 0.0783865 23.7 RPL7A missense lost rs782819119 0.991748663885 17136.0 0.00200481853504 0.252235 0.000592064181504 rs550057 22668.4 0.00150433828164 RPL7A 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136224646:T:C 9 136224646 C T 0.00109604 0.857463 38.8087 4.7E-10 -0.166533 27.3 SURF2 missense lost rs782095625 0.960470190793 17739.4 0.00210123225664 0.2618 0.015467938674 rs550057 22668.4 0.00278239370256 SURF2 0.0000 0.0000 0.0027 0.0002 biochemistry_AlkalinePhosphatase_v2 9:136272148:CCTT:C 9 136272148 C CCTT 0.00612174 0.952676 39.094 4.0E-10 0.0719302 20.2 REXO4 inframe_deletion lost rs672316 1.00094515394 2879.45 0.013589730625 0.106842 8.72670009744e-06 rs550057 22668.4 0.00201470811025 N/A N/A N/A N/A N/A biochemistry_AlkalinePhosphatase_v2 9:136277439:C:T 9 136277439 T C 0.000301889 0.956747 32.6306 1.1E-08 -0.276567 23.6 REXO4 missense lost rs368837729 0.915554455439 37.7645 0.791089282624 0.363777 0.0607666366715 rs550057 22668.4 0.00082619454096 REXO4 0.0000 0.0000 0.0209 0.0175 biochemistry_AlkalinePhosphatase_v2 9:136277979:G:A 9 136277979 A G 0.000256126 0.917359 38.8241 4.6E-10 -0.362169 24.3 REXO4 missense lost rs529134548 0.692065840164 415.708 0.064633909824 0.305507 1.09701171116 rs550057 22668.4 0.00066473730625 REXO4 0.0000 0.0000 0.0041 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136319670:C:T 9 136319670 T C 0.0012821 0.943663 43.226 4.9E-11 -0.167395 23.9 ADAMTS13 missense lost rs782095625 0.796876981633 17739.4 0.00194176829025 0.2618 0.497862138851 rs550057 22668.4 0.00251150320201 ADAMTS13 0.0000 0.0000 0.0000 0.0000 biochemistry_AlkalinePhosphatase_v2 9:136340625:C:T 9 136340625 T C 0.00776991 0.877975 55.9968 7.3E-14 0.0821245 LOW SLC2A6 missense lost 9:136137065:A:G 0.948116823806 17925.5 0.00296178673729 -0.254177 0.0386944214297 rs550057 22668.4 0.00212786618944 SLC2A6 0.9742 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_ApolipoproteinA_v2 11:14865399:C:T 11 14865399 T C 0.0010644 0.906863 110.533 7.5E-26 0.329813 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs558528882 69.2245 0.437394404164 PDE3B 0.1111 0.0139 0.0003 0.0000 biochemistry_ApolipoproteinA_v2 11:47290147:G:A 11 47290147 A G 0.000655145 0.910265 59.9433 9.8E-15 0.319017 33 NR1H3 missense won rs7111517 0.00316981800157 136.222 0.00139485069529 0.0259853 53.3835574879 rs141952264 196.515 0.00033491562049 NR1H3 0.0012 0.0004 0.0029 0.0000 biochemistry_ApolipoproteinA_v2 11:75509317:C:A 11 75509317 A C 0.000631832 0.899621 33.982 5.6E-09 -0.246314 36 DGAT2 stop_gained won rs11236557 0.00212170742266 77.5771 0.000929396196 -0.0174293 30.9235424045 rs11236557 77.5771 0.000929396196 DGAT2 0.0004 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 11:75511420:C:T 11 75511420 T C 0.000943814 0.955008 32.1404 1.4E-08 -0.170002 31 DGAT2 missense lost rs141370279 0.012193105056 125.06 0.00313362604944 0.0323667 25.4342514613 rs141370279 125.06 0.00313362604944 DGAT2 0.0002 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 11:116655859:C:T 11 116655859 T C 0.00544012 0.938996 74.3495 6.5E-18 0.118122 24.4 ZNF259 missense lost rs552561084 0.618051911779 93.7019 0.490404683521 -0.148268 3.39973185295 rs613808 2072.12 0.00899773662096 ZPR1 0.0004 0.0000 0.0002 0.0000 biochemistry_ApolipoproteinA_v2 11:116661001:G:A 11 116661001 A G 0.000401351 0.941055 34.3861 4.5E-09 -0.283385 24.4 APOA5 missense lost rs2727784 0.0105936099513 1767.33 0.00020611483489 0.0871196 27.6719760964 rs613808 2072.12 0.00014777562969 APOA5 0.0002 0.0000 0.0007 0.0000 biochemistry_ApolipoproteinA_v2 11:116661656:G:A 11 116661656 A G 0.000263487 0.934111 38.1404 6.6E-10 -0.394216 37 APOA5 stop_gained won rs73006533 0.00866949696468 81.1091 0.00407670757081 0.039004 31.3685426088 rs2727784 1767.33 0.000113656921 APOA5 0.0000 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 11:116701353:C:T 11 116701353 T C 0.000179988 0.815693 99.084 2.4E-23 0.793855 35 APOC3 stop_gained won rs2727784 0.0044161324793 1767.33 0.00024758707801 0.0871196 86.3525142389 rs2727784 1767.33 0.00024758707801 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 11:116701354:G:A 11 116701354 A G 0.00217696 0.92045 1488.46 1.3E-325 0.837274 31 APOC3 splice_donor won 11:116903390_CT_C 0.0123793618223 1495.78 0.0123187801 -0.113434 1175.66638372 rs613808 2072.12 0.00471802760641 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_ApolipoproteinA_v2 11:116701560:G:A 11 116701560 A G 0.00038225 0.859578 103.362 2.8E-24 0.560669 23.2 APOC3 missense won rs11216275 0.00267926318733 1157.57 0.00023923736929 -0.0816624 92.9385690975 rs11216275 1157.57 0.00023923736929 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 11:116706934:ACTT:A 11 116706934 A ACTT 0.000261376 0.80538 62.1465 3.2E-15 0.532881 20.4 APOA1 inframe_deletion won rs61903734 0.00229750701421 137.186 0.00104079147769 -0.0535785 56.3316305412 11:117109270:G:T 261.521 0.00011112322225 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 11:116707044:A:T 11 116707044 T A 0.000843044 0.946132 38.9862 4.3E-10 0.220359 25.2 APOA1 missense lost rs613808 0.102798504408 2072.12 0.00193411725796 0.0997668 17.994251657 rs613808 2072.12 0.00193411725796 APOA1 0.0005 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 11:116707739:A:C 11 116707739 C A 0.00100876 0.885482 371.434 9.1E-83 -0.649896 22.8 APOA1 missense won 11:116734545:G:A 0.00316069116962 685.483 0.00171264373281 -0.0550198 330.843930906 rs613808 2072.12 0.00035097399649 APOA1 0.0001 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 11:117222691:C:A 11 117222691 A C 0.00632829 0.971263 37.6264 8.6E-10 0.0729884 20.4 CEP164 missense lost rs142778341 0.998677778069 1041.99 0.036062389801 -0.128219 1.64561655799e-05 rs613808 2072.12 0.00500873260176 CEP164 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 12:109661672:A:G 12 109661672 G A 0.00197256 0.775439 35.57 2.5E-09 0.150203 24.1 ACACB missense won rs7312605 0.00585757668796 53.2849 0.00391018849225 -0.0175821 30.3336678303 rs2111216 193.882 0.00081478848025 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 12:111885310:G:A 12 111885310 A G 0.00200242 0.885884 66.7231 3.1E-16 -0.182955 32 SH2B3 missense lost rs570074821 0.968386399158 68.259 0.946596676624 0.179906 0.0169399375237 rs7296044 257.597 0.000152473104 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_ApolipoproteinA_v2 12:125284671:G:A 12 125284671 A G 0.0002435 0.922287 43.9232 3.4E-11 0.41993 31 SCARB1 missense lost 12:125333252_G_A 0.822693566145 47.2982 0.763989624225 -0.430037 0.379691073396 rs838876 369.344 0.00046716067321 SCARB1 0.0000 0.0000 0.0008 0.0004 biochemistry_ApolipoproteinA_v2 12:125292360:C:A 12 125292360 A C 0.000569018 0.940269 147.216 7.0E-34 0.525339 27.4 SCARB1 missense won rs921919 0.00284290177156 405.676 0.00103166228025 0.0434883 131.935739445 rs921919 405.676 0.00103166228025 SCARB1 0.0000 0.0000 0.0002 0.0000 biochemistry_ApolipoproteinA_v2 12:125294817:C:A 12 125294817 A C 0.000362323 0.939731 33.8983 5.8E-09 0.303297 24.2 SCARB1 missense lost rs80194043 0.0199294977155 66.6905 0.010130019904 -0.0439771 25.00290309 rs921919 405.676 0.00067513707556 SCARB1 0.3376 0.0693 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 12:125296427:C:T 12 125296427 T C 0.000219375 0.821747 44.5152 2.5E-11 0.48891 28.9 SCARB1 missense won rs80194043 0.00642938625617 66.6905 0.00429154699801 -0.0439771 37.6626404538 rs921919 405.676 0.000218271076 SCARB1 0.0003 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 12:125298855:T:C 12 125298855 C T 0.000283621 0.940952 72.2873 1.9E-17 0.476807 23.8 SCARB1 missense won rs921919 0.00253154377473 405.676 0.000451095121 0.0434883 65.1961071309 rs921919 405.676 0.000451095121 SCARB1 0.0002 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 12:125299614:C:T 12 125299614 T C 0.000600528 0.818572 71.6621 2.6E-17 0.355912 25.4 SCARB1 missense won 12:125288235_CAAAAAAAAAAAAA_C 0.00271806979108 274.835 0.00070872555961 0.0354022 64.3846595241 12:125288235_CAAAAAAAAAAAAA_C 274.835 0.00070872555961 SCARB1 0.0025 0.0006 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 15:58838103:A:ACG 15 58838103 ACG A 0.000501417 0.929914 128.67 8.0E-30 0.543131 35 LIPC frameshift won 15:58720262:T:C 0.00071405643794 183.824 0.00049981309225 0.122556 121.885280757 rs35717353 559.875 0.00013654623609 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 15:58840586:C:T 15 58840586 T C 0.00142546 0.933085 276.563 4.2E-62 0.445543 23.9 LIPC missense won rs473224 0.024634897539 2676.31 0.002545707025 0.146143 196.560164881 rs2070895 4720.37 0.00141733425625 LIPC 0.0033 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 15:58855748:C:T 15 58855748 T C 0.00197764 0.925982 264.473 1.8E-59 0.371182 24.2 LIPC missense won rs2043084 0.00560257410747 2930.91 0.00050555274025 -0.127045 226.362939134 rs261290 4933.07 0.00025455883401 LIPC 0.0024 0.0569 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 15:58855765:G:C 15 58855765 C G 0.000468239 0.890932 44.3019 2.8E-11 0.319547 25.0 LIPC missense won rs8033940 0.00988556145648 3102.49 0.00014116053721 -0.121712 35.9303134865 rs8033940 3102.49 0.00014116053721 LIPC 0.0051 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 15:90210353:CTTCTGCAGGGT:C 15 90210353 C CTTCTGCAGGGT 0.000303081 0.910204 45.6886 1.4E-11 0.409625 28.7 PLIN1 frameshift won N/A N/A N/A N/A N/A N/A 15:90210367:G:C 45.6886 1.0 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 15:90210367:G:C 15 90210367 C G 0.000303081 0.910204 45.6886 1.4E-11 0.409625 21.3 PLIN1 missense lost 15:90210353:CTTCTGCAGGGT:C 1.0 45.6886 1.0 0.409625 0.0 15:90210353:CTTCTGCAGGGT:C 45.6886 1.0 PLIN1 0.0243 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 15:90214777:A:G 15 90214777 G A 0.00118536 0.93376 41.6501 1.1E-10 0.187848 30 PLIN1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PLIN1 0.0192 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 16:57003551:G:A 16 57003551 A G 0.000256943 0.941636 76.5052 2.2E-18 0.557746 22.8 CETP missense won 16:57007353:C:T 0.038671687248 677.985 0.004363791481 0.116016 49.3741092011 rs12923459 5178.97 0.00019826611249 CETP 0.0341 0.0063 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 16:57007361:T:C 16 57007361 C T 0.000234348 0.917645 83.8631 5.3E-20 0.585083 23.9 CETP missense won rs564283356 0.0793044064845 214.121 0.0310605376 -0.200649 43.2803743461 16:56993324:C:A 9961.45 0.00043274816676 CETP 0.0004 0.0000 0.0068 0.0000 biochemistry_ApolipoproteinA_v2 16:57009034:TTCAACACCAA:T 16 57009034 T TTCAACACCAA 9.22622e-05 0.863326 41.8335 9.9E-11 0.717488 32 CETP frameshift won rs12720917 0.00370110092187 556.564 0.000278189041 -0.0677052 36.8983079891 rs289753 558.582 0.00013532436241 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 16:66956088:C:T 16 66956088 T C 1.89238e-05 0.843144 40.0479 2.5E-10 -1.57422 32 RRAD missense lost 16:67976870:G:T 0.850048954824 85.1106 0.399981618481 -1.30849 0.243770172353 rs377115620 87.037 0.00016869333924 RRAD 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 16:67166731:G:A 16 67166731 A G 0.0067719 0.967352 39.7886 2.8E-10 0.0734388 22.8 C16orf70 missense lost 16:67380155:G:A 0.998223739611 43.3026 0.917218021225 0.0766698 3.14121668926e-05 rs55781197 528.91 0.040903444516 C16orf70 0.0001 0.0480 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 16:67304881:G:A 16 67304881 A G 2.89466e-05 0.686311 81.6788 1.6E-19 -1.952 LOW SLC9A5 missense won rs78539049 0.0010063676909 222.471 0.00036948143961 0.0680617 76.5787569386 rs78539049 222.471 0.00036948143961 SLC9A5 0.7844 0.0000 0.0012 0.0000 biochemistry_ApolipoproteinA_v2 16:67575421:T:G 16 67575421 G T 0.00666101 0.970914 30.1737 4.0E-08 0.0632741 25.4 FAM65A missense lost rs71392173 0.976973190997 43.5173 0.677406364209 -0.0725645 0.00404650461553 rs55781197 528.91 0.043345158025 FAM65A 0.0010 0.0000 0.0125 0.0000 biochemistry_ApolipoproteinA_v2 16:67976870:G:T 16 67976870 T G 5.10982e-05 0.881171 85.1106 2.8E-20 -1.30849 36 LCAT stop_gained won rs377115620 0.000480567811431 87.037 0.00046993134841 0.0287632 81.4199366213 rs377115620 87.037 0.00046993134841 LCAT 0.1157 0.0040 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 17:40948319:C:T 17 40948319 T C 0.00358026 0.930029 33.7247 6.3E-09 -0.0960447 28.4 WNK4 missense lost 17:41001278:C:T 1.06097251236 36.7775 0.972904076881 -0.0987803 0.0304234974854 17:41926126:C:T 946.704 0.028938772996 WNK4 0.0000 0.0000 0.0003 0.0040 biochemistry_ApolipoproteinA_v2 17:40970264:C:T 17 40970264 T C 0.00303887 0.931723 34.428 4.4E-09 -0.103267 23.0 BECN1 missense lost rs145947882 0.996305978978 751.708 0.045630513769 0.171398 0.000117666758068 17:41926126:C:T 946.704 0.035212897801 BECN1 0.0000 0.0000 0.0046 0.0002 biochemistry_ApolipoproteinA_v2 18:47101922:G:A 18 47101922 A G 6.0073e-05 0.887131 30.3245 3.7E-08 0.676676 29.0 LIPG missense lost rs57256704 0.0109582809708 387.715 0.000857084176 -0.0783711 24.307957405 rs7229377 723.46 0.00011573886724 LIPG 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 18:47113165:C:T 18 47113165 T C 0.00263503 0.908785 721.912 5.1E-159 0.537522 29.8 LIPG missense won rs7229377 0.00838217199829 723.46 0.00836423651844 -0.0666167 595.775035659 18:47167214:C:T 2060.74 0.000529966441 LIPG 0.0000 0.0022 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 18:48331611:CAG:C 18 48331611 C CAG 0.00912009 0.947787 31.4399 2.1E-08 0.0597732 34 MRO frameshift lost rs549483920 0.397501105674 45.4526 0.274954458321 -0.109814 4.29303442154 18:47167214:C:T 2060.74 0.00014797262736 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 19:3382176:C:T 19 3382176 T C 0.00163946 0.909897 59.8099 1.0E-14 -0.195316 26.0 NFIC missense won N/A N/A N/A N/A N/A N/A rs12975319 57.6558 0.00337656290724 NFIC 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 19:11350874:C:T 19 11350874 T C 0.000461291 0.861956 49.4998 2.0E-12 0.331408 36 C19orf80 stop_gained won rs116846441 0.0194085033652 187.842 0.00511449534649 -0.217586 36.6684466924 19:8429323:G:A 427.797 0.00092265885009 DOCK6 0.0004 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 19:45667499:A:T 19 45667499 T A 0.00336574 0.913101 47.3776 5.9E-12 -0.123899 25.3 TRAPPC6A missense lost 19:45369564_AG_A 0.255767364853 249.079 0.048649801489 0.195786 11.5742720503 19:45411941:T:C 2355.23 0.00155446467289 TRAPPC6A 0.0067 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 19:50017538:G:C 19 50017538 C G 0.00818683 0.955029 33.1056 8.7E-09 0.0668847 22.6 FCGRT missense lost rs34296413 0.101468020001 41.8381 0.080289489316 -0.0258384 15.3738140617 19:50016759:C:T 74.5822 0.00094630679641 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_ApolipoproteinA_v2 1:63063287:C:G 1 63063287 G C 6.00583e-05 0.847978 35.4299 2.6E-09 -0.854264 24.8 ANGPTL3 missense won 1:62990602_CTATA_C 0.00223903572847 37.5744 0.00211124627289 -0.0427567 32.1562528951 rs9436221 559.365 0.00010073936161 DOCK7 0.1276 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 1:63063465:C:G 1 63063465 G C 0.00218746 0.867438 34.4351 4.4E-09 0.133236 23.0 ANGPTL3 missense lost rs373836691 0.00720782171892 190.747 0.00130121082729 -0.0304142 28.8362984482 rs912540 377.612 0.00056134403329 DOCK7 0.0003 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 1:63063592:GAACTC:G 1 63063592 G GAACTC 0.000628594 0.889289 184.494 5.1E-42 -0.558815 34 ANGPTL3 frameshift won rs370129568 0.00034742050042 191.726 0.00033431562649 -0.0318405 177.680448704 rs1183851 198.537 0.000293334129 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 1:63063667:CAACT:C 1 63063667 C CAACT 0.000235298 0.856004 86.5271 1.4E-20 -0.625901 33 ANGPTL3 frameshift won rs12079483 0.000365925333578 111.288 0.00028450918276 0.0268306 83.2483783934 rs1183851 198.537 0.00013545933769 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 1:63069706:T:G 1 63069706 G T 0.00041719 0.870862 174.722 6.9E-40 -0.702266 26.5 ANGPTL3 missense won rs374131620 0.000143112768925 195.424 0.00012795229456 -0.0326983 170.566615141 1:63130453_TA_T 199.999 0.00011764222369 DOCK7 0.0064 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 1:64089252:C:T 1 64089252 T C 0.000449999 0.922106 58.1129 2.5E-14 -0.378778 25.1 PGM1 missense lost rs574313788 0.850739212596 79.677 0.620491770369 0.509706 0.350345632405 1:63069706:T:G 174.722 0.191233913809 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 1:220101499:G:A 1 220101499 A G 0.00117989 0.883767 41.0832 1.5E-10 -0.191142 28.7 SLC30A10 missense won 1:220970028:A:G 0.000821399785847 290.476 0.00011617390656 0.0368828 38.7620507074 1:220970028:A:G 290.476 0.00011617390656 SLC30A10 0.0009 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 20:43042354:C:T 20 43042354 T C 0.0001755 0.965032 74.8422 5.1E-18 -0.63516 26.8 HNF4A missense won rs181884454 0.00883981096251 191.373 0.00345707544961 0.0738023 61.4304233631 rs181884454 191.373 0.00345707544961 HNF4A 0.0000 0.0050 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 2:21229160:C:T 2 21229160 T C 0.000364704 0.96006 65.5835 5.6E-16 -0.41292 24.9 APOB missense won 2:21208211:A:G 0.0015280165122 843.919 0.00011874678841 0.0675361 60.5564140825 2:21208211:A:G 843.919 0.00011874678841 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 2:21238367:C:T 2 21238367 T C 0.00515832 0.966793 67.8545 1.8E-16 0.116195 21.1 APOB missense lost rs142565602 0.898026165044 69.3216 0.879020628721 -0.127529 0.186010605754 rs2678379 916.474 0.019422045769 APOB 0.0691 0.0437 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 2:219878668:T:C 2 219878668 C T 0.00447761 0.931881 34.7295 3.8E-09 -0.0982807 25.7 CCDC108 missense lost rs115145659 0.917941519895 42.9342 0.742523443204 0.102371 0.0609928595611 rs78058190 238.17 0.089638563609 CCDC108 0.0000 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 4:100515943:A:C 4 100515943 C A 6.40487e-05 0.724397 41.0938 1.5E-10 -0.885989 22.2 MTTP missense won 4:103283117:A:G 0.000456068125867 184.911 0.00010135455625 -0.0511011 39.3573636032 4:103283117:A:G 184.911 0.00010135455625 MTTP 0.0226 0.0000 0.0073 0.0000 biochemistry_ApolipoproteinA_v2 4:110638764:A:G 4 110638764 G A 0.0017088 0.93174 98.8974 2.7E-23 -0.232139 25.5 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs113824614 46.1087 0.3460851241 PLA2G12A 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 4:110638824:C:T 4 110638824 T C 0.00775803 0.943901 300.474 2.6E-67 -0.20303 26.2 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs547113723 295.773 0.913165626409 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 6:31964621:G:GCT 6 31964621 GCT G 0.00482572 0.569777 31.3208 2.2E-08 -0.10971 34 C4A frameshift lost rs187570181 0.189968259149 49.5753 0.120018594969 0.0565658 9.9681982741 rs3129731 111.166 0.00205185444676 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 7:2296552:A:G 7 2296552 G A 0.00375744 0.988495 36.0572 1.9E-09 0.0977546 24.4 SNX8 missense won rs13226659 0.000494233764609 114.784 0.00015525409201 0.0217306 34.471818854 rs28522260 118.187 0.00012943157824 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_ApolipoproteinA_v2 7:80292304:A:G 7 80292304 G A 0.000380267 0.808064 40.1828 2.3E-10 0.342019 26.6 CD36 splice_acceptor won rs1761662 0.000375933904529 51.5725 0.00029290953316 -0.0127951 38.6396962492 rs1761662 51.5725 0.00029290953316 CD36 0.1307 0.3906 0.0001 0.0003 biochemistry_ApolipoproteinA_v2 8:19811733:G:A 8 19811733 A G 0.000434101 0.837003 224.667 8.7E-51 -0.785987 23.3 LPL missense won rs7826306 0.00323954182804 1092.2 0.00066637808449 -0.0682672 199.820086948 8:19824667:C:T 2276.47 0.00015106622281 LPL 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 8:19813594:G:A 8 19813594 A G 6.48359e-05 0.838027 37.9397 7.3E-10 -0.867252 28.6 LPL missense lost rs181349205 0.11020744747 528.562 0.00791059042225 0.269027 16.9308683261 8:19813529:A:G 1255.01 0.00305995942561 LPL 0.0000 0.0000 0.0058 0.6289 biochemistry_ApolipoproteinA_v2 9:104189856:C:G 9 104189856 G C 0.00549582 0.912482 44.7863 2.2E-11 0.0952878 27.2 ALDOB missense won rs139211342 0.00282197852635 92.594 0.00136494780304 -0.103476 40.1543836426 rs139211342 92.594 0.00136494780304 ALDOB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107555451:C:T 9 107555451 T C 1.51794e-05 0.901866 51.8568 6.0E-13 -1.88618 34 ABCA1 splice_donor won rs2777806 0.00124786815817 329.092 0.00019663331076 0.0668679 48.257809131 rs2777803 403.194 0.00014780723776 ABCA1 0.0443 0.0000 0.0438 0.9967 biochemistry_ApolipoproteinA_v2 9:107556776:T:G 9 107556776 G T 0.000341952 0.861164 405.415 3.6E-90 -1.1652 28.9 ABCA1 missense won rs10125482 0.00296586991636 1188.52 0.001011685249 0.105711 362.459767771 rs2740488 1880.42 0.00034580749681 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107558471:T:C 9 107558471 C T 0.000207926 0.933543 87.6346 7.9E-21 0.647643 22.5 ABCA1 missense won rs2254884 0.000686541397311 112.812 0.00053331897969 -0.0252914 83.1023725963 rs2254884 112.812 0.00053331897969 ABCA1 0.0465 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107560784:C:T 9 107560784 T C 0.000647479 0.88197 154.612 1.7E-35 -0.508871 34 ABCA1 missense won rs3905001 0.000705846097038 578.229 0.00018873539161 -0.0522807 146.505741946 rs3905001 578.229 0.00018873539161 ABCA1 0.0038 0.0000 0.0568 0.0000 biochemistry_ApolipoproteinA_v2 9:107562145:T:C 9 107562145 C T 0.000116751 0.903681 123.444 1.1E-28 -1.06997 24.4 ABCA1 missense won rs575148189 0.117461760997 128.35 0.112971948769 0.399529 53.3287788465 rs2740488 1880.42 0.00023683055449 ABCA1 0.0002 0.0000 0.0049 0.0027 biochemistry_ApolipoproteinA_v2 9:107566931:G:A 9 107566931 A G 3.55744e-05 0.953402 36.2638 1.7E-09 -1.03219 31 ABCA1 missense lost 9:107583681:GA:G 1.00930404425 36.6012 1.0 -1.0286 0.000781166336519 rs2740488 1880.42 0.00013430723881 ABCA1 0.0000 0.0000 0.0000 0.0953 biochemistry_ApolipoproteinA_v2 9:107571746:C:A 9 107571746 A C 2.84202e-05 0.923006 39.4911 3.3E-10 -1.15296 34 ABCA1 splice_donor won rs185776746 0.00465068987835 112.276 0.001635798025 0.0870704 34.2884933755 9:107665978:C:G 857.855 0.00015431105284 ABCA1 0.0000 0.0000 0.0997 0.9970 biochemistry_ApolipoproteinA_v2 9:107573080:C:A 9 107573080 A C 1.38017e-05 1 42.6776 6.5E-11 -1.69886 LOW NONE N/A won N/A N/A N/A N/A N/A N/A N/A N/A N/A ABCA1 0.0268 0.0000 0.3002 0.9956 biochemistry_ApolipoproteinA_v2 9:107574868:C:T 9 107574868 T C 2.55122e-05 0.851612 46.1285 1.1E-11 -1.40178 33 ABCA1 missense won 9:107666035:G:GC 0.00284148008097 797.675 0.00016431906969 -0.0893621 41.3417644547 9:107665978:C:G 857.855 0.00012731060224 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107578620:G:A 9 107578620 A G 0.00196836 0.918027 66.1023 4.3E-16 -0.193813 23.9 ABCA1 missense won rs2777800 0.037312582485 325.046 0.00758799530281 -0.0474262 43.0314920711 9:107666414:T:C 945.538 0.00125401682641 ABCA1 0.0416 0.0005 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107581111:C:A 9 107581111 A C 1.93617e-05 0.803005 39.7913 2.8E-10 -1.57053 33 ABCA1 missense won rs57320838 0.00372058470781 47.0437 0.00314700804324 0.100442 35.0850792117 rs57320838 47.0437 0.00314700804324 ABCA1 0.0007 0.0000 0.0015 0.0000 biochemistry_ApolipoproteinA_v2 9:107583681:GA:G 9 107583681 G GA 3.73261e-05 0.926185 36.6012 1.4E-09 -1.0286 34 ABCA1 frameshift won 9:107666035:G:GC 0.00742208304724 797.675 0.00034056118849 -0.0893621 30.5663596924 rs2740488 1880.42 0.00013431187449 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 9:107583726:T:C 9 107583726 C T 2.45035e-05 0.941877 40.922 1.6E-10 -1.32919 23.9 ABCA1 missense lost 9:107593919:T:A 0.847282501724 53.9363 0.642841547076 -1.26558 0.258770701932 9:107592356:C:T 60.3262 0.00032746159681 ABCA1 0.0002 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 9:107588169:CTG:C 9 107588169 C CTG 0.000132575 0.929249 101.934 5.7E-24 -0.912365 25.8 ABCA1 splice_acceptor won rs2275542 0.00125799665832 650.952 0.00019699245316 0.0544934 94.831391727 rs12001061 768.067 0.00015608004624 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinA_v2 9:107593272:G:A 9 107593272 A G 6.51459e-05 0.844356 63.5379 1.6E-15 -0.981547 26.4 ABCA1 missense won N/A N/A N/A N/A N/A N/A rs75242419 41.9153 0.00065645613796 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107593329:C:A 9 107593329 A C 0.000178143 0.816695 303.106 6.9E-68 -1.41994 28.6 ABCA1 missense won rs151158579 0.00828084763401 418.02 0.00600443663689 0.138289 250.451190111 rs2740488 1880.42 0.00041615184004 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107593339:G:A 9 107593339 A G 4.51347e-05 0.842989 127.216 1.7E-29 -1.74411 31 ABCA1 missense won rs4100654 0.00376400591649 1287.73 0.00037184951556 0.123014 112.085058247 rs13284054 1338.94 0.00026242380025 ABCA1 0.0363 0.0006 0.0001 0.0000 biochemistry_ApolipoproteinA_v2 9:107593919:T:A 9 107593919 A T 3.74343e-05 0.961955 53.9363 2.1E-13 -1.26558 29.4 ABCA1 missense won 9:107592356:C:T 0.000590082555522 60.3262 0.00052757955481 -0.0341481 51.3477272099 9:107592356:C:T 60.3262 0.00052757955481 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107599263:G:A 9 107599263 A G 4.67388e-05 0.659206 31.9954 1.5E-08 -1.00644 35 ABCA1 missense lost rs113206627 0.00935078562455 1242.68 0.00024075556569 0.115929 26.1067063015 rs13284054 1338.94 0.00020676714436 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinA_v2 9:107646756:G:A 9 107646756 A G 0.00134883 0.835804 65.8231 4.9E-16 -0.244364 25.0 ABCA1 missense won rs36050540 0.00234851686281 470.8 0.00032834889616 -0.0517989 59.5979145012 rs4149307 970.045 0.00010869939081 ABCA1 0.0004 0.0000 0.0000 0.0005 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_ApolipoproteinB_v2 10:52573772:C:T 10 52573772 T C 0.00986422 0.962839 95.5797 1.4E-22 0.100615 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs150770378 74.726 0.8688476944 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 11:14865399:C:T 11 14865399 T C 0.00106114 0.906863 46.4324 9.5E-12 -0.208209 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs10832250 32.159 0.00591424059681 PDE3B 0.1111 0.0139 0.0003 0.0000 biochemistry_ApolipoproteinB_v2 11:116701354:G:A 11 116701354 A G 0.00223463 0.92045 84.0807 4.7E-20 -0.184285 31 APOC3 splice_donor won rs61905084 0.00980264606095 104.559 0.00788275846801 0.0250522 68.2555368018 11:116648917:C:G 827.434 0.00024110946729 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_ApolipoproteinB_v2 12:109661672:A:G 12 109661672 G A 0.00198634 0.775439 33.3085 7.9E-09 -0.14738 24.1 ACACB missense won rs11065755 0.00222733394237 37.4435 0.00198136265625 -0.0152635 30.238723892 rs597808 130.651 0.00030907398025 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 15:101845482:G:A 15 101845482 A G 0.00500178 0.871604 30.7855 2.9E-08 -0.0817853 27.7 PCSK6 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PCSK6 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 17:7077063:C:G 17 7077063 G C 0.000227174 0.876384 42.6844 6.4E-11 -0.503282 26.2 ASGR1 missense won rs139295128 0.000281060241894 49.5583 0.00024207625744 0.0149333 41.265201643 rs139295128 49.5583 0.00024207625744 ASGR1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:11213450:G:A 19 11213450 A G 3.10539e-05 0.927448 30.6356 3.1E-08 1.01631 24.1 LDLR missense lost 19:11190764:G:A 0.0014286814581 103.081 0.00042460311481 0.0398827 28.36344565 19:11190764:G:A 103.081 0.00042460311481 LDLR 0.0000 0.0000 0.0022 0.0012 biochemistry_ApolipoproteinB_v2 19:11218182:A:C 19 11218182 C A 7.7583e-05 0.959902 36.1469 1.8E-09 0.635601 22.7 LDLR missense won 19:11170677:A:G 0.00376086091038 40.3834 0.0033663204 0.046057 31.8493641201 rs564282752 397.062 0.000169494361 LDLR 0.0000 0.0000 0.0005 0.0006 biochemistry_ApolipoproteinB_v2 19:11224296:G:A 19 11224296 A G 7.45366e-05 0.81432 47.8218 4.7E-12 0.916 29.8 LDLR missense won rs7251031 0.00113888228531 378.565 0.00014386803025 -0.0415569 44.6485472648 19:11275139:A:C 444.5 0.00010750164489 LDLR 0.0005 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:11227645:G:T 19 11227645 T G 0.000457398 0.847841 42.0352 9.0E-11 0.330127 20.1 LDLR missense won rs17842117 0.00479289417047 57.532 0.00350188182289 -0.0266835 36.4164149838 rs5742911 704.822 0.000178462881 LDLR 0.0001 0.0000 0.0127 0.0003 biochemistry_ApolipoproteinB_v2 19:11231112:C:T 19 11231112 T C 3.81773e-05 0.776697 33.4326 7.4E-09 1.08902 25.8 LDLR missense lost 19:9490773:G:A 0.909875911189 41.6911 0.7296405561 1.1348 0.0711309727148 19:9490773:G:A 41.6911 0.7296405561 LDLR 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:11312671:C:T 19 11312671 T C 0.00194392 0.854536 56.9244 4.5E-14 -0.167952 26.6 DOCK6 missense lost rs747875948 0.511858154324 3119.46 0.00934046864521 0.171607 4.60933362436 rs12151108 3212.7 0.00890524392976 DOCK6 0.0005 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:44130380:C:T 19 44130380 T C 0.000509993 0.92646 43.6501 3.9E-11 -0.288274 20.5 CADM4 missense lost rs141622900 0.982013182924 18735.9 0.00228785239225 0.613825 0.00356259362492 rs1065853 31008.2 0.00132156969156 CADM4 0.0122 0.0000 0.0002 0.0000 biochemistry_ApolipoproteinB_v2 19:44419110:C:G 19 44419110 G C 0.000184893 0.840402 31.6387 1.9E-08 -0.452395 20.8 ZNF45 missense lost rs148933445 0.958161006247 6559.96 0.00462121242025 0.580082 0.0141433495178 rs1065853 31008.2 0.00092359464649 ZNF45 0.0006 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:44652934:C:A 19 44652934 A C 0.000230283 0.793757 30.7908 2.9E-08 -0.414409 24.0 ZNF234 missense lost rs372583503 0.770576609238 35.764 0.663423282064 0.465188 0.459606497523 rs1065853 31008.2 0.00049610434756 ZNF234 0.0009 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:44662125:C:G 19 44662125 G C 0.000159176 0.908764 44.535 2.5E-11 -0.550504 35 ZNF234 stop_gained lost 19:44676921:C:T 0.970734196631 46.0517 0.938763334404 -0.643805 0.00967805875991 rs1065853 31008.2 0.00130259637225 ZNF234 0.0000 0.0000 0.0002 0.0000 biochemistry_ApolipoproteinB_v2 19:44932609:G:A 19 44932609 A G 0.000604006 0.747139 96.3734 9.5E-23 -0.444767 23.3 ZNF229 missense lost rs190712692 0.838482216584 19282.5 0.00419071085449 0.622382 0.685091980567 rs1065853 31008.2 0.00251771125824 ZNF229 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:44932910:C:CT 19 44932910 CT C 0.00539482 0.981222 295.776 2.7E-66 -0.228905 34 ZNF229 frameshift lost rs144627165 1.011719031 332.035 0.901236942225 0.261532 0.0100960781035 rs1065853 31008.2 0.012265784001 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 19:45127176:C:T 19 45127176 T C 0.000200921 0.928522 31.9092 1.6E-08 -0.423278 21.8 IGSF23 missense lost rs118147862 1.02153974606 13345.8 0.00244245500944 0.55509 0.00366182108298 rs1065853 31008.2 0.00094072250944 IGSF23 0.0001 0.0000 0.0002 0.0000 biochemistry_ApolipoproteinB_v2 19:45322101:T:G 19 45322101 G T 5.64154e-05 0.801138 30.6528 3.1E-08 0.749635 20.7 BCAM missense lost 19:45322099:G:C 1.0 30.6528 1.0 0.749635 0.0 19:45411941:T:C 9000.06 0.00029356367569 BCAM 0.0000 0.0000 0.0205 0.0039 biochemistry_ApolipoproteinB_v2 19:45322904:C:T 19 45322904 T C 0.0020047 0.972321 59.6595 1.1E-14 0.177181 25.1 BCAM missense lost rs150966173 1.09929212658 1342.11 0.048865755136 -0.217091 0.140168186465 rs1065853 31008.2 0.00011002121881 BCAM 0.0002 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:45391526:G:A 19 45391526 A G 0.00028934 0.771006 126.517 2.4E-29 -0.722632 25.1 PVRL2 missense lost rs1065853 0.523673793947 31008.2 0.00213664893121 0.633616 9.66180153955 rs1065853 31008.2 0.00213664893121 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 19:45404058:C:T 19 45404058 T C 0.00179942 0.927388 116.418 3.9E-27 0.255245 25.2 TOMM40 missense lost 19:45385421:T:C 1.01138258869 124.209 0.947943693376 0.261885 0.00374956611011 rs1065853 31008.2 0.00015604007056 TOMM40 0.0000 0.0000 0.0003 0.0000 biochemistry_ApolipoproteinB_v2 19:45411987:G:A 19 45411987 A G 0.000122029 0.846733 35.1721 3.0E-09 -0.547013 24.5 APOE missense lost rs190712692 0.745358996956 19282.5 0.00135956650729 0.622382 0.656855645431 rs1065853 31008.2 0.00076179312036 APOE 0.0004 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinB_v2 19:45412314:T:A 19 45412314 A T 0.000835994 0.914716 35.4819 2.6E-09 -0.204285 24.3 APOE missense lost rs4803760 0.228717794973 3520.89 0.00230491209025 -0.144059 9.65919538541 19:45411941:T:C 9000.06 0.00011197237489 APOE 0.0000 0.0000 0.0004 0.0000 biochemistry_ApolipoproteinB_v2 19:45493709:T:G 19 45493709 G T 0.000231836 0.689227 42.8441 5.9E-11 -0.505198 24.3 CLPTM1 missense lost rs144311893 0.653066682205 8150.63 0.00343287012649 0.617001 1.57734227421 rs1065853 31008.2 0.00082500498441 CLPTM1 0.0006 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:45567663:G:A 19 45567663 A G 0.000215172 0.76135 54.275 1.7E-13 -0.544252 22.1 CLASRP missense lost rs190712692 0.830164622828 19282.5 0.00233668792449 0.622382 0.428621557385 rs1065853 31008.2 0.00143973954721 CLASRP 0.0322 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:45567745:G:GTCCCGC 19 45567745 GTCCCGC G 0.00713039 0.906612 112.537 2.7E-26 0.123327 20.3 CLASRP inframe_insertion lost 19:45496095:C:T 0.724932690102 223.378 0.365218374889 0.263768 2.48404122113 19:45411941:T:C 9000.06 0.0031058329 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 19:45641786:G:A 19 45641786 A G 0.00176216 0.881007 196.422 1.3E-44 -0.350075 23.0 PPP1R37 missense lost 19:45389596:G:A 0.95957224466 9905.75 0.0190274436 -0.554784 0.0819227139446 rs1065853 31008.2 0.00727293424225 PPP1R37 0.0074 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 19:45683003:A:G 19 45683003 G A 0.000206096 0.671911 31.5724 1.9E-08 -0.48649 25.7 BLOC1S3 missense lost rs111784051 0.99436294164 10585.7 0.00296573911396 0.591863 0.00025152394408 rs1065853 31008.2 0.00092449443025 BLOC1S3 0.0000 0.0000 0.0203 0.0000 biochemistry_ApolipoproteinB_v2 19:45721556:G:A 19 45721556 A G 0.00033172 0.943987 34.5387 4.2E-09 -0.304821 25.3 EXOC3L2 missense lost rs186462625 0.736043303076 2835.17 0.00896665061776 0.774195 0.69712847313 rs1065853 31008.2 0.00077389119721 EXOC3L2 0.0013 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinB_v2 19:45850048:C:T 19 45850048 T C 7.38976e-05 0.76933 35.2431 2.9E-09 -0.762997 LOW NONE N/A lost rs1065853 0.543428760443 31008.2 0.00061764675625 0.633616 2.43446457213 rs1065853 31008.2 0.00061764675625 KLC3 0.0003 0.0000 0.7692 0.0000 biochemistry_ApolipoproteinB_v2 19:46282700:G:A 19 46282700 A G 0.000123253 0.870284 30.4819 3.4E-08 -0.492162 21.0 NONE N/A lost 19:45412079:C:T 1.04012009229 30960.4 0.00102404480049 -0.634693 0.0120260262414 rs1065853 31008.2 0.001024512064 DMPK 0.0003 0.0000 0.8494 0.0395 biochemistry_ApolipoproteinB_v2 1:55505598:G:GCGCA 1 55505598 GCGCA G 7.10357e-05 0.895178 57.221 3.9E-14 -0.967205 23.4 PCSK9 frameshift won rs545634492 0.00138839862013 82.8572 0.00095882503201 0.0358477 53.0361968581 rs2479410 275.375 0.000101465329 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 1:55512267:C:A 1 55512267 A C 0.000102076 0.941969 66.7447 3.1E-16 -0.81484 24.1 PCSK9 missense won rs4927205 0.00337076034531 192.421 0.00116920911969 0.0503007 59.2195194854 1:55719166:T:G 272.418 0.00015909533689 PCSK9 0.0003 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 1:55518085:G:T 1 55518085 T G 0.000140901 0.952882 111.668 4.2E-26 -0.886329 28.2 PCSK9 splice_donor won rs116264584 0.00390753204501 124.362 0.00350867860281 0.0610208 98.1435558619 rs200730299 475.627 0.000659770596 PCSK9 0.0002 0.0000 0.8531 0.9899 biochemistry_ApolipoproteinB_v2 1:55518374:C:T 1 55518374 T C 0.0013037 0.813031 231.827 2.4E-52 -0.437477 24.4 PCSK9 missense won N/A N/A N/A N/A N/A N/A 1:55493843_CG_C 173.116 0.00026820940441 PCSK9 0.0002 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 1:55524201:T:C 1 55524201 C T 0.000351106 0.836139 109.624 1.2E-25 -0.609817 21.7 PCSK9 missense won rs4927207 0.00295074080153 226.911 0.00142554574096 0.0416926 98.0377624274 rs17111503 344.002 0.00010651065616 PCSK9 0.0014 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 1:55524309:G:A 1 55524309 A G 0.000345994 0.815522 150.787 1.2E-34 -0.706243 23.0 PCSK9 missense won rs10888896 0.000893973763837 222.062 0.00060703597161 -0.0338254 141.904919764 rs499883 338.339 0.000373223761 PCSK9 0.0000 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinB_v2 1:55527230:G:A 1 55527230 A G 0.000318599 0.972056 287.614 1.6E-64 -0.926848 23.8 PCSK9 splice_donor won N/A N/A N/A N/A N/A N/A rs11436234 277.604 0.00052722588996 PCSK9 0.0004 0.0000 0.5440 0.9807 biochemistry_ApolipoproteinB_v2 1:57409364:C:G 1 57409364 G C 0.000170551 0.973534 30.9326 2.7E-08 -0.422771 LOW NONE N/A won N/A N/A N/A N/A N/A N/A rs79494709 29.8472 0.00014590465681 C8B 0.0000 0.0000 0.1020 0.9229 biochemistry_ApolipoproteinB_v2 1:109793077:C:A 1 109793077 A C 0.00613161 0.975014 74.8574 5.1E-18 -0.112419 23.0 CELSR2 missense lost rs6677122 0.981998562693 545.528 0.134749928889 0.11534 0.00611962385911 1:109817192:A:G 4813.53 0.02056356 CELSR2 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 1:109824680:C:T 1 109824680 T C 0.00849356 0.988638 46.6108 8.7E-12 -0.0733381 23.0 PSRC1 missense lost 1:109820884:A:G 1.00547571418 1768.36 0.026502537616 -0.140659 0.00034843478553 1:109817192:A:G 4813.53 0.00703677711025 PSRC1 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 1:110020621:A:G 1 110020621 G A 0.00556968 0.940413 58.3239 2.2E-14 -0.10762 25.3 SYPL2 missense lost rs570439166 0.993016107446 62.712 0.923532532036 0.11057 0.000713677794123 1:109817192:A:G 4813.53 0.014275231441 SYPL2 0.0000 0.0000 0.0002 0.0762 biochemistry_ApolipoproteinB_v2 1:110050180:C:T 1 110050180 T C 0.00696535 0.964489 79.7389 4.3E-19 -0.105945 22.5 AMIGO1 missense lost 1:109822166:A:G 1.01541838177 4582.77 0.017667992241 -0.156749 0.00470282668436 1:109817192:A:G 4813.53 0.0180606721 AMIGO1 0.0001 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21228431:A:C 2 21228431 C A 6.06814e-05 0.814739 46.1934 1.1E-11 -0.928503 24.2 APOB missense won rs35098041 0.00823772595071 2314.31 0.00016442419984 -0.115415 38.1887253065 rs35098041 2314.31 0.00016442419984 APOB 0.0182 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21228891:CA:C 2 21228891 C CA 0.000103714 0.642863 201.39 1.0E-45 -1.84155 25.3 APOB frameshift won rs6728178 0.000864635394724 1293.95 0.00013457160025 0.0824057 189.720510619 2:21208211:A:G 1334.19 0.00012613760721 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 2:21229068:G:A 2 21229068 A G 0.00108198 0.934139 100.688 1.1E-23 0.300645 26.1 APOB missense won rs112507407 0.080883848817 406.215 0.020048577649 -0.103024 51.5605255108 rs548145 3026.71 0.00018916976521 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21229160:C:T 2 21229160 T C 0.000358004 0.96006 413.945 5.1E-92 1.04279 24.9 APOB missense won rs35258479 0.00308230576714 1399.05 0.000911979601 -0.0835184 369.257679744 rs577584 2656.75 0.00010041643264 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21229501:AG:A 2 21229501 A AG 2.77375e-05 0.888846 60.2906 8.2E-15 -1.53221 35 APOB frameshift won rs540156 0.000632222367544 152.692 0.00024963368004 0.0360043 57.2968194609 rs9967685 187.407 0.00014641968016 N/A N/A N/A N/A N/A biochemistry_ApolipoproteinB_v2 2:21232176:G:A 2 21232176 A G 2.27246e-05 0.967799 172.298 2.3E-39 -2.70828 37 APOB stop_gained won rs672889 0.00130795078652 2067.58 0.00010899568801 -0.126269 160.06083543 rs672889 2067.58 0.00010899568801 APOB 0.0000 0.0000 0.0064 0.0000 biochemistry_ApolipoproteinB_v2 2:21238367:C:T 2 21238367 T C 0.00513449 0.966793 368.527 3.9E-82 -0.263479 21.1 APOB missense lost rs146536216 0.701196262356 377.834 0.683924038009 0.22508 9.74643822725 rs548145 3026.71 0.019752897025 APOB 0.0691 0.0437 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21242613:G:A 2 21242613 A G 0.00137379 0.895455 170.778 5.0E-39 0.352423 22.6 APOB missense won 2:21364562:C:T 0.0649273747071 417.345 0.026568348004 0.0987455 94.8347931377 rs548145 3026.71 0.00029086279209 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 2:21245889:G:A 2 21245889 A G 0.000324795 0.86451 39.1623 3.9E-10 -0.339709 24.5 APOB missense won rs4635554 0.00462613984018 1673.09 0.000108284836 -0.0840444 34.0161652502 rs4635554 1673.09 0.000108284836 APOB 0.0047 0.0000 0.0001 0.0000 biochemistry_ApolipoproteinB_v2 2:21255263:G:A 2 21255263 A G 0.000108187 0.667184 80.1738 3.4E-19 -1.06228 37 APOB stop_gained won rs76611756 0.00538515638503 496.935 0.00086882278564 0.102402 68.8386603391 rs1848922 1752.52 0.00014692348944 APOB 0.0000 0.0000 0.0001 0.0013 biochemistry_ApolipoproteinB_v2 2:21256168:T:C 2 21256168 C T 3.99008e-05 0.782873 70.3191 5.0E-17 -1.43454 LOW NONE N/A won rs60403635 0.00516810247433 642.281 0.000565821369 0.120084 60.5721042212 rs1713222 2254.79 0.00010981572849 APOB 0.0006 0.0000 0.2812 0.6207 biochemistry_ApolipoproteinB_v2 2:21260958:C:A 2 21260958 A C 1.88231e-05 0.788057 107.098 4.2E-25 -2.75188 34 APOB stop_gained won rs375330151 0.000816825632494 590.989 0.00014802372225 -0.0927845 101.063724115 rs375330151 590.989 0.00014802372225 APOB 0.0000 0.5731 0.0142 0.0000 biochemistry_ApolipoproteinB_v2 2:44040341:A:G 2 44040341 G A 0.00106652 0.929326 32.9995 9.2E-09 0.175477 23.6 ABCG5 missense lost rs558688363 0.347199175617 48.8034 0.234766413729 -0.157162 5.56790616376 rs4299376 569.287 0.00078923912356 ABCG5 0.0001 0.0000 0.0003 0.0000 biochemistry_ApolipoproteinB_v2 4:155489608:C:T 4 155489608 T C 0.00594038 0.942434 37.2842 1.0E-09 0.0791183 25.2 FGB missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A FGB 0.0001 0.0000 0.0018 0.0004 biochemistry_ApolipoproteinB_v2 6:160831796:G:A 6 160831796 A G 0.000934822 0.983352 46.2904 1.0E-11 0.225902 20.5 SLC22A3 missense lost rs576888780 0.886172931121 48.4415 0.846821412441 -0.242979 0.159135286635 6:160575985:C:T 229.488 0.00043040066521 SLC22A3 0.0003 0.0019 0.0000 0.0000 biochemistry_ApolipoproteinB_v2 7:2296552:A:G 7 2296552 G A 0.00374226 0.988495 54.2574 1.8E-13 0.115031 24.4 SNX8 missense lost rs77523736 0.777653875148 55.6048 0.758809983409 -0.130582 0.757442296826 rs77523736 55.6048 0.758809983409 SNX8 0.0000 0.0000 0.0000 0.0001 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_AspartateAminotransferase_v2 10:17794492:G:T 10 17794492 T G 0.00656302 0.951531 178.217 1.2E-40 0.171166 25.8 TMEM236 missense lost rs550182667 0.748478931479 2349.48 0.056774975625 -0.194985 3.24094635866 10:17875857:G:T 5001.38 0.00290951281201 TMEM236 0.0000 0.0000 0.0011 0.0000 biochemistry_AspartateAminotransferase_v2 10:17838274:C:T 10 17838274 T C 0.00954081 0.944664 181.437 2.4E-41 -0.141038 25.3 TMEM236 missense lost rs4638208 0.741264969401 625.362 0.2150640625 0.144199 3.5071857049 10:17875857:G:T 5001.38 0.014835483601 TMEM236 0.0000 0.0000 0.0001 0.0000 biochemistry_AspartateAminotransferase_v2 10:100186970:A:C 10 100186970 C A 2.96273e-05 0.712997 76.3885 2.3E-18 -1.83853 26.4 HPS1 splice_donor lost rs772136632 1.10077657754 1365.94 0.061559564544 3.79016 0.184751255651 10:101157378:CGTT:C 2796.1 0.00494165414961 HPS1 0.0002 0.0000 0.5707 0.9431 biochemistry_AspartateAminotransferase_v2 10:101090207:G:A 10 101090207 A G 4.05084e-05 0.575052 66.0653 4.4E-16 -1.62294 31 CNNM1 missense won rs527506472 0.0941922867994 573.879 0.010843473424 0.602347 31.7362537992 10:101101889_GT_G 576.479 0.00964960440976 CNNM1 0.0000 0.0000 0.0000 0.0000 biochemistry_AspartateAminotransferase_v2 10:101157306:A:G 10 101157306 G A 2.84768e-05 0.706724 43.0391 5.4E-11 -1.42039 21.7 GOT1 stop_lost won rs200945612 0.00198943247905 384.048 0.00022294969225 0.0697462 39.2853727295 rs148695914 402.595 0.00012334989969 GOT1 0.0001 0.0000 0.0000 0.0000 biochemistry_AspartateAminotransferase_v2 10:101157378:CGTT:C 10 101157378 C CGTT 0.000452181 0.956373 2796.1 1.0E-609 -2.52126 22.3 GOT1 inframe_deletion won N/A N/A N/A N/A N/A N/A rs147566295 2470.87 0.915994469776 N/A N/A N/A N/A N/A biochemistry_AspartateAminotransferase_v2 10:101163627:C:T 10 101163627 T C 9.42394e-05 0.877145 205.516 1.3E-46 -1.54969 26.0 GOT1 missense won rs200945612 0.00105369150917 384.048 0.00056386301764 0.0697462 192.390199067 rs4423123 466.706 0.00011740372609 GOT1 0.1973 0.0235 0.0001 0.0000 biochemistry_AspartateAminotransferase_v2 10:101165895:T:G 10 101165895 G T 0.000172627 0.845566 57.5576 3.3E-14 0.653487 25.9 GOT1 missense won rs10883451 0.00129323665938 614.846 0.00012106380841 0.0491946 53.4923088463 10:101912064:T:C 615.813 0.00012065045281 GOT1 0.0000 0.0000 0.0035 0.0830 biochemistry_AspartateAminotransferase_v2 10:101180383:G:A 10 101180383 A G 2.36003e-05 0.831989 49.4015 2.1E-12 -1.63453 34 GOT1 missense won rs565567278 0.00102090030925 74.2047 0.00067966054209 0.0669745 46.2950269263 rs56333232 131.584 0.00019678758961 GOT1 0.0000 0.0000 0.0486 0.0000 biochemistry_AspartateAminotransferase_v2 11:22242646:C:CA 11 22242646 CA C 0.0030298 0.964303 114.836 8.5E-27 0.1991 24.3 ANO5 frameshift won rs138701515 0.00619117106643 124.364 0.00571684185604 -0.0264433 97.4754588249 rs12574283 188.873 0.00135046695169 N/A N/A N/A N/A N/A biochemistry_AspartateAminotransferase_v2 11:47290147:G:A 11 47290147 A G 0.000655536 0.910265 35.4843 2.6E-09 0.252019 33 NR1H3 missense lost rs568132453 0.479024062457 36.4662 0.466125714756 -0.25534 3.3636553601 rs11039265 159.07 0.00032609497561 NR1H3 0.0012 0.0004 0.0029 0.0000 biochemistry_AspartateAminotransferase_v2 19:45811692:C:G 19 45811692 G C 0.00312612 0.953381 45.0535 1.9E-11 0.130266 23.7 CKM missense won rs5112 0.000947965760822 86.4108 0.00049425737761 -0.0201954 42.3219000116 rs157595 88.6667 0.00012226388329 CKM 0.0087 0.0000 0.0017 0.0012 biochemistry_AspartateAminotransferase_v2 19:50017538:G:C 19 50017538 C G 0.00820173 0.955029 45.4553 1.6E-11 -0.0759076 22.6 FCGRT missense lost rs376672989 0.044947408497 50.4384 0.040506795169 0.0194822 28.2246199294 rs376672989 50.4384 0.040506795169 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_AspartateAminotransferase_v2 1:220101499:G:A 1 220101499 A G 0.00118277 0.883767 146.901 8.3E-34 0.37317 28.7 SLC30A10 missense won N/A N/A N/A N/A N/A N/A rs718700 51.3126 0.00036247209769 SLC30A10 0.0009 0.0000 0.0000 0.0000 biochemistry_AspartateAminotransferase_v2 2:39241107:G:A 2 39241107 A G 0.0096922 0.95699 38.1314 6.6E-10 -0.0630512 23.0 SOS1 missense won N/A N/A N/A N/A N/A N/A rs115393289 36.4273 0.90706576 SOS1 0.0005 0.0000 0.0000 0.0000 biochemistry_AspartateAminotransferase_v2 2:101924635:T:C 2 101924635 C T 0.00513932 0.887631 35.6822 2.3E-09 0.0845143 23.3 RNF149 missense lost rs2278721 0.0326877779701 50.4205 0.023132889025 -0.0199642 23.9460584401 rs4851389 72.1545 0.00205931717209 RNF149 0.0001 0.0000 0.0463 0.0008 biochemistry_AspartateAminotransferase_v2 4:8235220:C:A 4 8235220 A C 0.00831282 0.880974 56.0977 6.9E-14 0.0853501 24.2 SH3TC1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SH3TC1 0.0000 0.0000 0.0000 0.0002 biochemistry_AspartateAminotransferase_v2 7:2296552:A:G 7 2296552 G A 0.00374404 0.988495 37.5574 8.9E-10 0.100526 24.4 SNX8 missense won rs28600085 0.0001443466521 40.167 0.00013496862976 -0.0169366 36.6603593912 rs10265736 40.747 0.00013273113681 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_AspartateAminotransferase_v2 8:22885843:C:T 8 22885843 T C 0.000855215 0.84979 37.7255 8.1E-10 -0.231897 22.6 TNFRSF10B splice_donor won 8:22828704_AT_A 0.00032630703532 40.009 0.00030768317281 -0.0138078 36.3748654472 rs12155880 60.7359 0.00019431802404 TNFRSF10B 0.0001 0.0000 0.1188 0.9908 biochemistry_AspartateAminotransferase_v2 9:117354865:A:C 9 117354865 C A 0.00516467 0.933193 42.9839 5.5E-11 -0.0917925 22.7 ATP6V1G1 missense won 9:117155662_AT_A 0.00225803741606 99.838 0.00097216745616 0.0234836 38.9958715986 9:117122615:C:A 156.5 0.00030825527184 ATP6V1G1 0.0000 0.1039 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Calcium_v2 10:52573772:C:T 10 52573772 T C 0.00990816 0.962839 34.833 3.6E-09 0.0650605 23.4 A1CF missense won rs4838384 0.00168275156407 69.8758 0.00083884957641 0.0187983 32.0338215695 rs10857463 87.7572 0.00032339907889 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_Calcium_v2 14:94847386:G:A 14 94847386 A G 0.00426702 0.970109 97.34 5.8E-23 0.158052 23.1 SERPINA1 missense won rs61280460 0.0278444043425 169.035 0.016034397129 -0.0335623 67.5648183787 rs965344 169.33 0.015560317081 SERPINA1 0.0004 0.0000 0.0301 0.0000 biochemistry_Calcium_v2 19:50017538:G:C 19 50017538 C G 0.0081988 0.955029 236.551 2.2E-53 -0.183505 22.6 FCGRT missense won N/A N/A N/A N/A N/A N/A rs187560607 161.401 0.7920644004 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_Calcium_v2 19:50154190:G:A 19 50154190 A G 0.00540821 0.95981 36.5685 1.5E-09 -0.087909 23.2 SCAF1 missense lost rs187882126 0.95635703365 52.2714 0.669056925681 0.0860976 0.0178037546211 19:50016759:C:T 113.781 0.000538379209 SCAF1 0.0001 0.0000 0.0000 0.0000 biochemistry_Calcium_v2 3:121615340:G:T 3 121615340 T G 0.000694229 0.883742 57.402 3.6E-14 0.328486 33 SLC15A2 missense lost rs576875550 0.482043442428 298.973 0.092551025284 -0.220574 5.36458850353 rs73186030 3805.06 0.00320574513249 SLC15A2 0.0000 0.0001 0.0006 0.8773 biochemistry_Calcium_v2 3:121712695:G:A 3 121712695 A G 4.97894e-05 0.677623 33.8464 6.0E-09 -1.05881 22.3 ILDR1 missense lost rs776641580 0.244281607576 244.848 0.033768105121 0.5327 8.65738623647 rs576458949 333.67 0.020608612249 ILDR1 0.0002 0.0000 0.0002 0.0000 biochemistry_Calcium_v2 3:121973215:G:T 3 121973215 T G 1.38845e-05 0.733663 34.906 3.5E-09 1.91037 31 CASR missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CASR 0.0000 0.0000 0.0000 0.0000 biochemistry_Calcium_v2 3:122000982:G:A 3 122000982 A G 0.00158412 0.952918 296.944 1.5E-66 -0.463598 23.5 CASR missense lost rs576458949 1.07445216946 333.67 0.9561906225 0.517604 0.396858574524 rs73186030 3805.06 0.00015377488036 CASR 0.0001 0.0005 0.0000 0.0000 biochemistry_Calcium_v2 3:126741151:A:G 3 126741151 G A 3.67073e-05 0.873822 36.8203 1.3E-09 -1.15221 27.6 PLXNA1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PLXNA1 0.0000 0.0000 0.0000 0.0004 biochemistry_Calcium_v2 4:74274363:A:G 4 74274363 G A 0.000776616 0.878554 116.062 4.6E-27 -0.424881 24.7 ALB missense won N/A N/A N/A N/A N/A N/A rs189666604 84.0029 0.491656197124 ALB 0.0000 0.0000 0.0000 0.0000 biochemistry_Calcium_v2 6:10877397:C:T 6 10877397 T C 0.00091548 0.858943 47.6116 5.2E-12 0.26081 29.7 GCM2 missense lost rs551058413 0.679902506431 51.8989 0.6237366529 -0.318176 1.46541309451 rs551058413 51.8989 0.6237366529 RP11-637O19.3 0.0283 0.0000 0.0000 0.0000 biochemistry_Calcium_v2 7:2296552:A:G 7 2296552 G A 0.00376638 0.988495 46.6906 8.3E-12 -0.113417 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs559517076 38.4964 0.756578134225 SNX8 0.0000 0.0000 0.0000 0.0001 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Cholesterol_v2 10:52573772:C:T 10 52573772 T C 0.00987533 0.962839 53.3978 2.7E-13 0.0790005 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs144458455 41.9963 0.451804442896 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 11:116707739:A:C 11 116707739 C A 0.00101081 0.885482 37.0425 1.2E-09 -0.204747 22.8 APOA1 missense won rs525028 0.00480941407351 498.333 0.00035749733776 0.0485935 32.0828624717 11:116623213_TA_T 592.003 0.00011492912025 APOA1 0.0001 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 12:111885310:G:A 12 111885310 A G 0.0019994 0.885884 32.1306 1.4E-08 -0.13316 32 SH2B3 missense lost rs565349424 0.00409916126138 132.717 0.00099240120576 -0.0231551 28.1480049353 rs565349424 132.717 0.00099240120576 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_Cholesterol_v2 12:125292360:C:A 12 125292360 A C 0.0005681 0.940269 44.1678 3.0E-11 0.27197 27.4 SCARB1 missense won rs921919 0.00165895284162 67.1887 0.00109054494756 0.0176507 40.6431416846 rs838912 76.9597 0.00054677871889 SCARB1 0.0000 0.0000 0.0002 0.0000 biochemistry_Cholesterol_v2 17:7077063:C:G 17 7077063 G C 0.000227361 0.876384 30.3534 3.6E-08 -0.421262 26.2 ASGR1 missense lost rs17880560 0.00039147147398 32.8425 0.00036180224521 0.0118986 29.1641597168 rs1050541 54.2679 0.00011126874256 ASGR1 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 18:47113165:C:T 18 47113165 T C 0.0026614 0.908785 128.782 7.6E-30 0.224579 29.8 LIPG missense won rs8090363 0.00219011509719 190.143 0.00148334360164 -0.0286156 117.010395909 rs10438978 306.219 0.00053563547844 LIPG 0.0000 0.0022 0.0000 0.0000 biochemistry_Cholesterol_v2 19:11224296:G:A 19 11224296 A G 7.99499e-05 0.81432 53.2205 3.0E-13 0.963399 29.8 LDLR missense won rs78043647 0.000827129323875 59.6386 0.00073811652489 -0.0296086 50.2032923912 rs113783450 320.838 0.00011735605561 LDLR 0.0005 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 19:11227645:G:T 19 11227645 T G 0.000458416 0.847841 39.09 4.0E-10 0.325775 20.1 LDLR missense won rs17842117 0.00703756775925 77.9337 0.003529904569 -0.0316907 32.8065617077 rs5742911 564.306 0.00017753430564 LDLR 0.0001 0.0000 0.0127 0.0003 biochemistry_Cholesterol_v2 19:11231112:C:T 19 11231112 T C 4.0284e-05 0.776697 36.9277 1.2E-09 1.09176 25.8 LDLR missense lost 19:9490773:G:A 0.873406185189 43.1939 0.746699917924 1.13646 0.158129142162 19:9490773:G:A 43.1939 0.746699917924 LDLR 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 19:11312671:C:T 19 11312671 T C 0.0019422 0.854536 42.9872 5.5E-11 -0.154511 26.6 DOCK6 missense lost rs77265569 0.567687223457 2597.31 0.00939559937481 0.162561 2.61305422037 19:11196356_AC_A 2690.56 0.00889137729481 DOCK6 0.0005 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 19:44932910:C:CT 19 44932910 CT C 0.00542867 0.981222 86.9478 1.1E-20 -0.12296 34 ZNF229 frameshift lost rs187408586 1.02687525477 826.641 0.108008850609 0.381337 0.0154926550444 rs1065853 10221.8 0.012417536356 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 19:45391526:G:A 19 45391526 A G 0.000293505 0.771006 52.8735 3.6E-13 -0.508975 25.1 PVRL2 missense lost rs148933445 0.462191106893 2507.64 0.00974528301124 0.367823 5.4194458394 rs1065853 10221.8 0.00220602120489 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 19:45404058:C:T 19 45404058 T C 0.00179748 0.927388 36.4534 1.6E-09 0.147104 25.2 TOMM40 missense lost 19:45413234_GGT_G 1.01314119982 3248.37 0.011369530384 -0.177404 0.00156353811617 rs1065853 10221.8 0.00016037436321 TOMM40 0.0000 0.0000 0.0003 0.0000 biochemistry_Cholesterol_v2 19:45567745:G:GTCCCGC 19 45567745 GTCCCGC G 0.00712738 0.906612 64.3224 1.1E-15 0.0944063 20.3 CLASRP inframe_insertion lost 19:45496095:C:T 0.578293513892 101.824 0.365309030464 0.183601 3.69090096027 19:45411941:T:C 3599.31 0.00310165455625 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 19:45641786:G:A 19 45641786 A G 0.00177244 0.881007 51.6568 6.6E-13 -0.18741 23.0 PPP1R37 missense lost rs112450640 0.8897098881 1638.67 0.028046870784 0.296951 0.166397129633 rs1065853 10221.8 0.00733938316804 PPP1R37 0.0074 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 1:55505598:G:GCGCA 1 55505598 GCGCA G 7.52928e-05 0.895178 50.2803 1.3E-12 -0.901821 23.4 PCSK9 frameshift won rs545634492 0.00154167941924 70.8337 0.00109433932864 0.0341849 46.4093820095 rs2479410 208.841 0.00010087189225 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 1:55512267:C:A 1 55512267 A C 0.000101579 0.941969 42.224 8.1E-11 -0.68637 24.1 PCSK9 missense won rs79702288 0.00460821420539 166.802 0.00116651620849 0.0487332 36.6859236666 1:55719166:T:G 237.721 0.00015834698896 PCSK9 0.0003 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 1:55518085:G:T 1 55518085 T G 0.000144791 0.952882 89.5855 2.9E-21 -0.812618 28.2 PCSK9 splice_donor won rs116264584 0.0040364171848 99.9799 0.00361677148816 0.0561768 78.5638684252 rs4927191 349.951 0.00032523958336 PCSK9 0.0002 0.0000 0.8531 0.9899 biochemistry_Cholesterol_v2 1:55518374:C:T 1 55518374 T C 0.00130757 0.813031 179.58 6.0E-41 -0.396364 24.4 PCSK9 missense won N/A N/A N/A N/A N/A N/A 1:55493843_CG_C 139.228 0.00027189041881 PCSK9 0.0002 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 1:55524201:T:C 1 55524201 C T 0.00035064 0.836139 92.8218 5.7E-22 -0.580314 21.7 PCSK9 missense won rs4927207 0.00302515228302 197.253 0.0014235529 0.0403237 82.8919450801 rs17111503 287.211 0.00010724052249 PCSK9 0.0014 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 1:55524309:G:A 1 55524309 A G 0.000349901 0.815522 131.489 1.9E-30 -0.686474 23.0 PCSK9 missense won rs10888896 0.000860928414569 178.139 0.00063547351396 -0.0309554 123.886012153 rs499883 305.339 0.000369831361 PCSK9 0.0000 0.0000 0.0001 0.0000 biochemistry_Cholesterol_v2 1:55527230:G:A 1 55527230 A G 0.000323378 0.972056 251.507 1.2E-56 -0.881191 23.8 PCSK9 splice_donor won N/A N/A N/A N/A N/A N/A 1:55719166:T:G 237.721 0.00045886780944 PCSK9 0.0004 0.0000 0.5440 0.9807 biochemistry_Cholesterol_v2 1:63063592:GAACTC:G 1 63063592 G GAACTC 0.000624298 0.889289 151.871 6.8E-35 -0.515014 34 ANGPTL3 frameshift won rs370129568 0.00063612712117 296.698 0.00032561480704 -0.0396989 144.30676199 rs370129568 296.698 0.00032561480704 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 1:63063667:CAACT:C 1 63063667 C CAACT 0.000238121 0.856004 52.7639 3.8E-13 -0.517441 33 ANGPTL3 frameshift won rs1183851 0.00076575279415 287.514 0.00014052917025 -0.0349859 49.8841136338 rs1183851 287.514 0.00014052917025 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 1:63069706:T:G 1 63069706 G T 0.000412167 0.870862 117.439 2.3E-27 -0.568224 26.5 ANGPTL3 missense won 1:63131385_CAA_C 0.000670551800861 132.034 0.00059642919961 0.030135 111.435579604 1:63130453_TA_T 191.189 0.00011982367296 DOCK7 0.0064 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 1:64089252:C:T 1 64089252 T C 0.000447091 0.922106 35.3745 2.7E-09 -0.297634 25.1 PGM1 missense lost rs574313788 1.039908826 58.3032 0.630947439684 0.429244 0.0138111240051 1:63069706:T:G 117.439 0.192713098081 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 1:110020621:A:G 1 110020621 G A 0.00556981 0.940413 34.6184 4.0E-09 -0.0866672 25.3 SYPL2 missense lost rs190115410 0.984457164662 40.2325 0.847084618384 0.0907975 0.00210718380519 1:109817192:A:G 1778.76 0.014249674384 SYPL2 0.0000 0.0000 0.0002 0.0762 biochemistry_Cholesterol_v2 1:110050180:C:T 1 110050180 T C 0.00696087 0.964489 31.998 1.5E-08 -0.0658911 22.5 AMIGO1 missense lost 1:109817590:G:T 1.00051374141 1769.47 0.018092671081 -0.102175 2.11076778145e-06 1:109817192:A:G 1778.76 0.018038370249 AMIGO1 0.0001 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 2:21228587:G:C 2 21228587 C G 1.88971e-05 0.805907 59.0485 1.5E-14 -2.05474 35 APOB stop_gained won rs36134738 0.00113966900731 387.721 0.00017356745025 0.0782033 55.1289610004 rs36134738 387.721 0.00017356745025 APOB 0.0000 0.0000 0.0001 0.0000 biochemistry_Cholesterol_v2 2:21228891:CA:C 2 21228891 C CA 0.000147111 0.642863 304.182 4.0E-68 -1.7966 25.3 APOB frameshift won 2:21232804:G:A 0.000492749536921 1181.15 0.00012689797201 0.0690131 290.827444312 2:21232804:G:A 1181.15 0.00012689797201 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 2:21229068:G:A 2 21229068 A G 0.00108155 0.934139 69.559 7.4E-17 0.263203 26.1 APOB missense won rs112507407 0.0580373073318 201.089 0.020075772721 -0.0742453 40.0811922976 rs581411 1402.34 0.00019061391969 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 2:21229160:C:T 2 21229160 T C 0.000358543 0.96006 254.177 3.2E-57 0.84228 24.9 APOB missense won rs4635554 0.00212842963973 779.02 0.00069445952676 -0.0596734 231.26513337 rs581411 1402.34 0.00010220401216 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 2:21229501:AG:A 2 21229501 A AG 3.67329e-05 0.888846 56.2856 6.3E-14 -1.31341 35 APOB frameshift won rs4503953 0.00054963830092 299.647 0.00010324388881 0.037049 53.6773762986 rs9678877 300.144 0.00010033427889 N/A N/A N/A N/A N/A biochemistry_Cholesterol_v2 2:21232176:G:A 2 21232176 A G 3.06205e-05 0.967799 115.59 5.8E-27 -1.92027 37 APOB stop_gained won rs672889 0.00129703025877 1047.92 0.00014306791321 -0.0923956 107.414136396 rs672889 1047.92 0.00014306791321 APOB 0.0000 0.0000 0.0064 0.0000 biochemistry_Cholesterol_v2 2:21238367:C:T 2 21238367 T C 0.00514774 0.966793 123.655 1.0E-28 -0.159104 21.1 APOB missense lost rs563222733 0.557200535233 184.244 0.373964048676 0.125093 7.94894029315 rs581411 1402.34 0.019697280409 APOB 0.0691 0.0437 0.0000 0.0000 biochemistry_Cholesterol_v2 2:21242613:G:A 2 21242613 A G 0.0013752 0.895455 140.757 1.8E-32 0.329878 22.6 APOB missense won 2:21364562:C:T 0.0390251366762 206.233 0.026635219209 0.0710392 90.6375873775 rs581411 1402.34 0.00029761425225 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 2:21255263:G:A 2 21255263 A G 0.00013665 0.667184 148.614 3.5E-34 -1.20603 37 APOB stop_gained won rs1848922 0.00138798421156 795.285 0.000259371025 -0.0702888 137.746848537 rs1848922 795.285 0.000259371025 APOB 0.0000 0.0000 0.0001 0.0013 biochemistry_Cholesterol_v2 2:21256168:T:C 2 21256168 C T 4.65576e-05 0.782873 47.725 4.9E-12 -1.14016 LOW NONE N/A won rs553448422 0.00531262656828 268.348 0.00094483693924 0.0860649 41.0214077493 rs581411 1402.34 0.00012025534921 APOB 0.0006 0.0000 0.2812 0.6207 biochemistry_Cholesterol_v2 2:21260958:C:A 2 21260958 A C 2.98279e-05 0.788057 142.432 7.8E-33 -2.46518 34 APOB stop_gained won rs34601365 0.000821303849913 1096.89 0.000106646929 -0.0840871 134.385233694 rs34601365 1096.89 0.000106646929 APOB 0.0000 0.5731 0.0142 0.0000 biochemistry_Cholesterol_v2 2:26534339:T:G 2 26534339 G T 4.46052e-05 0.681414 33.3765 7.6E-09 -1.08855 26.8 GPR113 missense won rs148977667 0.00067085734276 40.1485 0.00055770128649 0.0414256 31.6699271621 rs78653657 84.2638 0.00012021368164 ADGRF3 0.0020 0.0000 0.0001 0.0000 biochemistry_Cholesterol_v2 2:44040341:A:G 2 44040341 G A 0.00106565 0.929326 32.3667 1.3E-08 0.182156 23.6 ABCG5 missense lost rs559411103 0.661570209552 34.4256 0.622003523584 -0.2468 1.12736072431 rs4299376 641.639 0.00078342890404 ABCG5 0.0001 0.0000 0.0003 0.0000 biochemistry_Cholesterol_v2 4:155489608:C:T 4 155489608 T C 0.00593346 0.942434 48.0296 4.2E-12 0.0930834 25.2 FGB missense won N/A N/A N/A N/A N/A N/A rs34784687 42.6149 0.000140090896 FGB 0.0001 0.0000 0.0018 0.0004 biochemistry_Cholesterol_v2 6:160831796:G:A 6 160831796 A G 0.000937112 0.983352 42.5154 7.0E-11 0.218347 20.5 SLC22A3 missense lost rs576888780 0.88698466406 44.5388 0.846688904649 -0.236012 0.144016631361 rs112939444 170.643 0.000574369156 SLC22A3 0.0003 0.0019 0.0000 0.0000 biochemistry_Cholesterol_v2 7:2296552:A:G 7 2296552 G A 0.00374409 0.988495 73.6358 9.4E-18 0.142279 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs539144005 61.9171 0.592775266561 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_Cholesterol_v2 9:107556776:T:G 9 107556776 G T 0.000334017 0.861164 47.7635 4.8E-12 -0.420626 28.9 ABCA1 missense won 9:107665978:C:G 0.00685604061169 311.254 0.001052094096 -0.0538776 40.181217173 rs2740488 503.523 0.00034046892324 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 9:107558471:T:C 9 107558471 C T 0.000216667 0.933543 31.1879 2.3E-08 0.397059 22.5 ABCA1 missense lost rs2254884 0.000840189055094 47.4107 0.00055269659025 -0.0163812 29.4060778691 rs2254884 47.4107 0.00055269659025 ABCA1 0.0465 0.0000 0.0000 0.0000 biochemistry_Cholesterol_v2 9:107562145:T:C 9 107562145 C T 0.000118456 0.903681 40.9397 1.6E-10 -0.615068 24.4 ABCA1 missense won 9:107665978:C:G 0.00528645078989 311.254 0.00069533470864 -0.0538776 35.2028396873 rs2740488 503.523 0.00025604160169 ABCA1 0.0002 0.0000 0.0049 0.0027 biochemistry_Cholesterol_v2 9:107593329:C:A 9 107593329 A C 0.000180776 0.816695 35.3522 2.8E-09 -0.515362 28.6 ABCA1 missense lost rs150183551 0.0197371635359 119.021 0.00586242892225 0.0767503 26.1167605902 rs2740488 503.523 0.000435181321 ABCA1 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_CreactiveProtein_v2 10:90982268:C:T 10 90982268 T C 0.00131554 0.936179 40.9315 1.6E-10 -0.168987 21.2 NONE N/A won rs1332328 0.00166372002043 187.839 0.00036253683216 -0.0282148 37.6605112283 10:91002927:C:T 196.078 0.00026717863936 LIPA 0.0000 0.0000 0.0001 0.9091 biochemistry_CreactiveProtein_v2 11:116701354:G:A 11 116701354 A G 0.00223332 0.92045 42.3044 7.8E-11 0.149161 31 APOC3 splice_donor lost rs530885291 0.714763153885 45.8421 0.6596038656 -0.178898 1.01064469765 rs530885291 45.8421 0.6596038656 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_CreactiveProtein_v2 12:121416756:A:G 12 121416756 G A 0.000249785 0.899065 59.5516 1.2E-14 0.513213 22.7 HNF1A missense won 12:121401709_TCTCAGCTCACTGCAAC_T 0.0242402980666 1867.07 0.00077316251364 -0.106907 42.4516186764 rs7970695 6883.66 0.00014289094369 HNF1A 0.0000 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 12:121437410:G:A 12 121437410 A G 0.00118746 0.881013 31.3533 2.2E-08 -0.169495 21.9 HNF1A missense lost rs192127960 0.536086389065 80.8418 0.207913200625 0.119168 2.24890881045 rs7970695 6883.66 0.00175606254916 HNF1A 0.0001 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 12:121570899:G:T 12 121570899 T G 0.00908031 0.917804 48.4445 3.4E-12 -0.0717366 31 P2RX7 splice_donor lost rs1169312 0.997589260003 5580.27 0.00866046139456 0.150303 7.04707985371e-05 rs7970695 6883.66 0.00727139925625 P2RX7 0.0017 0.0000 0.0354 0.9917 biochemistry_CreactiveProtein_v2 14:94847386:G:A 14 94847386 A G 0.00423934 0.970109 32.6164 1.1E-08 -0.0844896 23.1 SERPINA1 missense lost rs117839260 0.819552348514 41.536 0.643558532841 0.0907791 0.292560521427 rs61980636 54.3426 0.016173226276 SERPINA1 0.0004 0.0000 0.0301 0.0000 biochemistry_CreactiveProtein_v2 16:1828030:G:A 16 1828030 A G 0.00666423 0.933647 40.5602 1.9E-10 0.0833559 23.6 SPSB3 missense won 16:1129010:C:A 0.000172348797595 48.1775 0.00014509888849 0.0297553 39.5022282544 16:1129010:C:A 48.1775 0.00014509888849 SPSB3 0.0289 0.0035 0.0001 0.0000 biochemistry_CreactiveProtein_v2 17:7077097:C:T 17 7077097 T C 2.79758e-05 0.838847 44.4291 2.6E-11 -1.31839 26.5 ASGR1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ASGR1 0.0001 0.0000 0.0001 0.0000 biochemistry_CreactiveProtein_v2 17:41063408:C:T 17 41063408 T C 0.000364264 0.927043 44.3536 2.7E-11 0.349922 35 G6PC stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A G6PC 0.0535 0.0000 0.0001 0.0000 biochemistry_CreactiveProtein_v2 19:45322904:C:T 19 45322904 T C 0.00200367 0.972321 72.0924 2.1E-17 -0.177958 25.1 BCAM missense lost rs6857 0.922143655454 8938.85 0.00743714787321 0.241301 0.113720799716 19:45411941:T:C 11799.3 0.00811755950625 BCAM 0.0002 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 19:45385488:G:A 19 45385488 A G 0.00610317 0.919755 57.8135 2.9E-14 0.0940025 24.9 PVRL2 missense lost 19:45394819:T:G 0.878863955612 150.207 0.338267865664 0.0937041 0.225997028192 19:45411941:T:C 11799.3 0.00108340380801 N/A N/A N/A N/A N/A biochemistry_CreactiveProtein_v2 19:45404058:C:T 19 45404058 T C 0.00179494 0.927388 122.331 2.0E-28 -0.26006 25.2 TOMM40 missense lost 19:45413234_GGT_G 0.943849151823 10171.6 0.011351410849 0.30143 0.0992309701608 19:45411941:T:C 11799.3 0.00938027116324 TOMM40 0.0000 0.0000 0.0003 0.0000 biochemistry_CreactiveProtein_v2 19:45412358:C:G 19 45412358 G C 0.000969934 0.89329 100.097 1.5E-23 -0.31505 23.2 APOE missense lost rs149591953 0.941035951813 179.915 0.523552097761 0.420683 0.0896669293576 19:45411941:T:C 11799.3 0.00479110383684 APOE 0.0000 0.0000 0.0013 0.0000 biochemistry_CreactiveProtein_v2 19:45567745:G:GTCCCGC 19 45567745 GTCCCGC G 0.00713013 0.906612 102.146 5.2E-24 -0.123287 20.3 CLASRP inframe_insertion lost 19:45496095:C:T 1.0098857221 282.444 0.365225626921 -0.295319 0.00248335854025 19:45411941:T:C 11799.3 0.00310840815961 N/A N/A N/A N/A N/A biochemistry_CreactiveProtein_v2 19:45667499:A:T 19 45667499 T A 0.00338396 0.913101 40.3577 2.1E-10 -0.113149 25.3 TRAPPC6A missense lost 19:45369564_AG_A 1.01981419838 855.32 0.048119248321 0.353276 0.00392236905335 19:45411941:T:C 11799.3 0.00150092706724 TRAPPC6A 0.0067 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 19:45900279:A:C 19 45900279 C A 0.00446656 0.959517 31.686 1.8E-08 -0.0813228 21.9 PPP1R13L missense lost rs564589315 0.52740951122 40.9189 0.408405352356 0.116439 2.37487210122 19:45411941:T:C 11799.3 0.00106259700625 PPP1R13L 0.0000 0.0000 0.0001 0.0000 biochemistry_CreactiveProtein_v2 1:63789765:A:G 1 63789765 G A 0.00015042 0.894778 32.424 1.2E-08 0.464666 22.6 FOXD3 missense lost 1:65321305:G:A 0.808104016896 80.1895 0.326750567641 0.828941 0.331110613252 rs72683129 3385.64 0.00023457066649 FOXD3 0.0006 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:65312368:C:T 1 65312368 T C 0.00167879 0.945214 49.4203 2.1E-12 0.168815 26.3 JAK1 missense won rs140079251 0.0300836125196 246.436 0.00603297065284 -0.0907367 33.7635066378 rs4655537 3210.62 0.00011993754256 JAK1 0.0000 0.0000 0.0000 0.0005 biochemistry_CreactiveProtein_v2 1:65321305:G:A 1 65321305 A G 0.000124132 0.934859 80.1895 3.4E-19 0.828941 22.8 JAK1 missense won rs55953331 0.0125096222729 3334.48 0.00030083861809 -0.157276 63.2548229276 rs72683129 3385.64 0.00029262549969 JAK1 0.0006 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:66083694:G:A 1 66083694 A G 0.00133338 0.927377 87.2222 9.7E-21 0.251231 27.8 LEPR missense won rs6696954 0.0784410793946 2898.19 0.00236071600384 0.108433 45.2067766368 rs1938495 4938.46 0.00077076195876 LEPR 0.0003 0.0000 0.0001 0.0000 biochemistry_CreactiveProtein_v2 1:66102657:CAT:C 1 66102657 C CAT 4.06532e-05 0.91729 30.4753 3.4E-08 0.869689 34 LEPR frameshift lost rs140079251 0.00957320479566 246.436 0.00118386229329 -0.0907367 24.8034716373 rs61799395 758.164 0.00011531752996 N/A N/A N/A N/A N/A biochemistry_CreactiveProtein_v2 1:151804213:G:A 1 151804213 A G 0.00341681 0.949492 36.1169 1.9E-09 0.104897 36 RORC stop_gained won rs12083537 0.00421837064063 925.713 0.00016458067521 0.0695009 31.5777424845 1:154516477:G:A 1155.83 0.00010213932096 RORC 0.0001 0.0000 0.0000 0.0145 biochemistry_CreactiveProtein_v2 1:153784559:G:A 1 153784559 A G 0.00801394 0.953675 31.2153 2.3E-08 -0.0641029 23.0 GATAD2B missense lost rs138696756 0.745072780617 35.8402 0.6489269136 0.0588168 0.58437573642 1:154420087:G:A 2805.67 0.00657391775209 GATAD2B 0.0013 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:159035800:G:A 1 159035800 A G 6.48684e-05 0.692802 49.433 2.1E-12 -0.946406 22.0 AIM2 missense lost rs538923691 0.698191283933 689.409 0.050062720009 0.904184 1.33639437903 1:159683814:G:A 2095.38 0.012514225689 AIM2 0.0002 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:159410354:A:T 1 159410354 T A 0.00506716 0.912039 42.9765 5.5E-11 -0.0866002 24.1 OR10J1 missense lost rs115984621 0.956424533526 473.38 0.0868304089 0.10611 0.0208581559223 rs7551731 9053.11 0.00016997901376 OR10J1 0.0012 0.0000 0.0201 0.0000 biochemistry_CreactiveProtein_v2 1:159683321:C:T 1 159683321 T C 3.12607e-05 0.920229 30.1837 3.9E-08 -0.929953 41 CRP stop_gained lost rs140936230 0.0856978138509 85.4395 0.030274956009 0.350881 15.0983103655 1:159683438:C:G 5438.86 0.00044983440649 CRP 0.0000 0.0000 0.0211 0.0000 biochemistry_CreactiveProtein_v2 1:159683797:G:A 1 159683797 A G 4.07071e-05 0.713594 33.7664 6.2E-09 -1.03537 23.2 CRP missense won rs779432580 0.00081920514988 214.931 0.00012869994916 -0.0357404 31.8611540099 rs779432580 214.931 0.00012869994916 CRP 0.0001 0.0000 0.0360 0.0000 biochemistry_CreactiveProtein_v2 1:159683816:G:C 1 159683816 C G 0.000201633 0.898028 97.8027 4.6E-23 -0.698086 34 CRP stop_gained won 1:159652615_CA_C 0.00465475290415 3254.66 0.00013987556361 0.115594 84.9126223673 1:159652615_CA_C 3254.66 0.00013987556361 CRP 0.0042 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:159752046:A:T 1 159752046 T A 0.00722937 0.93002 33.1504 8.5E-09 -0.064149 26.9 DUSP23 missense lost rs75771160 0.974428667047 692.25 0.046663344289 0.0883815 0.00548961991478 rs7551731 9053.11 0.00943518879801 DUSP23 0.0015 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:198222215:C:G 1 198222215 G C 0.00866559 0.968055 49.2074 2.3E-12 -0.0720526 23.1 NEK7 missense lost rs143554274 0.831111116549 49.8902 0.819736484449 0.0791965 0.384073586696 rs200639793 52.2884 0.00032919747844 NEK7 0.0000 0.0098 0.0000 0.0000 biochemistry_CreactiveProtein_v2 1:247607973:C:T 1 247607973 T C 0.000630033 0.922242 67.0124 2.7E-16 -0.322578 26.2 NLRP3 missense won rs4925547 0.00165354933616 307.495 0.00036035808561 -0.0345236 61.6732428924 rs4925659 310.544 0.00028288212481 NLRP3 0.0207 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 20:60886008:G:A 20 60886008 A G 0.00203062 0.891142 69.0744 9.5E-17 0.194161 23.5 LAMA5 missense lost rs185738008 0.896144939068 349.947 0.176885854084 -0.228865 0.196606107633 rs185738008 349.947 0.176885854084 LAMA5 0.0000 0.0000 0.0000 0.0015 biochemistry_CreactiveProtein_v2 2:27594142:A:C 2 27594142 C A 0.00834491 0.934706 33.2883 7.9E-09 -0.0630752 29.4 SNX17 missense lost rs190848277 1.02838618724 65.6128 0.5217461824 0.0749793 0.00661220588708 2:27730940:T:C 2014.03 0.00501643559824 SNX17 0.0000 0.0005 0.0172 0.0001 biochemistry_CreactiveProtein_v2 2:27677498:C:A 2 27677498 A C 0.00558764 0.919774 35.2711 2.9E-09 0.0799076 30 IFT172 missense lost 2:27672200:C:T 1.0 35.2711 1.0 0.0799076 0.0 2:27730940:T:C 2014.03 0.00811676666761 IFT172 0.0016 0.0154 0.0000 0.0000 biochemistry_CreactiveProtein_v2 3:126070736:G:A 3 126070736 A G 0.000241819 0.92825 48.3818 3.5E-12 0.436977 25.4 KLF15 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A KLF15 0.0000 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 9:107593329:C:A 9 107593329 A C 0.000176493 0.816695 345.98 3.2E-77 -1.51329 28.6 ABCA1 missense won N/A N/A N/A N/A N/A N/A rs766990564 175.487 0.574233559524 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 9:107599376:A:G 9 107599376 G A 0.00519049 0.942103 30.8513 2.8E-08 0.0770284 21.8 ABCA1 missense lost rs4149349 0.0021780751693 41.0724 0.00163604879361 -0.0136162 28.0388451852 rs2150867 46.9836 0.0011498881 ABCA1 0.0155 0.0000 0.0000 0.0000 biochemistry_CreactiveProtein_v2 9:139259592:C:G 9 139259592 G C 0.00523826 0.792909 36.3508 1.6E-09 -0.0980371 23.6 CARD9 splice_donor won N/A N/A N/A N/A N/A N/A 9:139410589:A:G 34.4125 0.00252949649481 CARD9 0.0015 0.0000 0.0142 0.8775 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Creatinine_v2 10:16992011:G:A 10 16992011 A G 0.00255362 0.913785 47.4094 5.8E-12 -0.142325 24.9 CUBN missense won N/A N/A N/A N/A N/A N/A rs184374646 40.1602 0.855613900036 CUBN 0.0000 0.0000 0.0001 0.0091 biochemistry_Creatinine_v2 11:65147013:C:T 11 65147013 T C 0.00734435 0.969748 48.3357 3.6E-12 -0.0833743 27.2 SLC25A45 missense lost rs145455132 0.899952407253 48.5 0.8969037025 0.0848364 0.127411888963 rs11227277 170.581 0.00445199876289 SLC25A45 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 11:65386404:A:C 11 65386404 C A 0.00749851 0.9327 36.1895 1.8E-09 -0.0716146 23.8 PCNXL3 missense lost 11:65305309:G:T 0.939958452937 46.3139 0.734479852324 -0.0790336 0.0336331811123 rs11227277 170.581 0.00622828748025 SIPA1 0.0000 0.0000 0.0006 0.0000 biochemistry_Creatinine_v2 11:65561574:C:T 11 65561574 T C 0.00996039 0.905052 29.951 4.4E-08 0.0559927 22.5 OVOL1 missense lost rs118011173 0.203130094255 61.5458 0.098852390464 -0.0281153 9.03714435206 rs11227277 170.581 0.00938867978304 OVOL1 0.0016 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 11:116701354:G:A 11 116701354 A G 0.00223203 0.92045 47.9997 4.3E-12 0.148444 31 APOC3 splice_donor won N/A N/A N/A N/A N/A N/A rs530885291 40.8322 0.659111788449 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_Creatinine_v2 15:45654348:C:T 15 45654348 T C 0.000105281 0.945033 36.474 1.5E-09 -0.590846 31 GATM missense won rs34611304 0.000359723818267 60.7255 0.00021606354081 0.0185192 35.1035606015 rs34611304 60.7255 0.00021606354081 GATM 0.0001 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 15:57731228:A:G 15 57731228 G A 0.0006006 0.889538 29.7678 4.9E-08 0.230774 28.6 CGNL1 missense lost rs4774940 0.000417563276987 47.9228 0.00025937424601 0.0150109 28.5636577533 rs4774940 47.9228 0.00025937424601 CGNL1 0.0000 0.0000 0.0099 0.0000 biochemistry_Creatinine_v2 15:65447268:A:G 15 65447268 G A 0.00315632 0.957335 44.432 2.6E-11 0.119808 27.4 CLPX missense lost rs112838612 1.01699177356 51.6991 0.87403801 -0.133606 0.00318014461025 rs553245596 117.192 0.00079991677584 CLPX 0.0000 0.0000 0.0031 0.0000 biochemistry_Creatinine_v2 16:2004119:C:T 16 2004119 T C 0.0041439 0.866465 32.9749 9.3E-09 -0.0922623 24.3 RPL3L missense lost rs338787 0.0255989670651 39.9967 0.021104825625 0.0183391 23.267268262 16:2160973:A:G 78.6961 0.000133217764 RPL3L 0.1017 0.0021 0.0000 0.0000 biochemistry_Creatinine_v2 16:20477021:G:A 16 20477021 A G 0.00850334 0.871773 49.2107 2.3E-12 -0.0755746 38 ACSM2A stop_gained lost 16:20407525:C:T 0.520052709127 108.063 0.236826275904 -0.0754065 3.82658005663 rs77924615 1139.8 0.021515315761 ACSM2A 0.0177 0.0000 0.0000 0.1196 biochemistry_Creatinine_v2 16:20551987:A:T 16 20551987 T A 0.00693143 0.897466 43.5533 4.1E-11 -0.0772738 27.1 ACSM2B missense lost rs77924615 0.220335791996 1139.8 0.00841932869761 0.0836647 12.2618655119 rs77924615 1139.8 0.00841932869761 ACSM2B 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 17:19459205:T:A 17 19459205 A T 0.0019054 0.922165 96.2493 1.0E-22 0.221129 29.2 SLC47A1 missense won rs2453584 0.00739095411012 270.276 0.00263202859089 -0.0335403 80.4114427714 rs8071709 275.482 0.00219115737604 SLC47A1 0.0007 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 17:19470502:G:A 17 19470502 A G 0.000715396 0.812632 42.462 7.2E-11 0.267791 24.9 SLC47A1 missense won 17:19463343:G:A 0.001401814687 69.1598 0.00086067130384 0.0159644 39.3419000151 rs74555736 98.1125 0.00027378335296 SLC47A1 0.0017 0.0000 0.0000 0.3311 biochemistry_Creatinine_v2 17:19584896:G:T 17 19584896 T G 0.00105665 0.961124 63.5997 1.5E-15 0.253933 23.9 SLC47A2 missense lost 17:19474875:C:T 0.535462082137 496.853 0.068541858025 0.205963 4.57641747112 17:19474875:C:T 496.853 0.068541858025 SLC47A2 0.0018 0.0000 0.0002 0.0000 biochemistry_Creatinine_v2 17:38416827:G:A 17 38416827 A G 0.00733876 0.992005 33.7651 6.2E-09 -0.0669299 23.4 WIPF2 missense lost rs188195622 1.03191347405 35.5537 0.9800010025 0.0700274 0.00846267741926 rs7218484 451.203 0.00530265045249 WIPF2 0.0003 0.0588 0.0000 0.0000 biochemistry_Creatinine_v2 19:33355167:C:T 19 33355167 T C 0.000679358 0.977599 36.6669 1.4E-09 -0.230344 26.2 SLC7A9 missense lost rs140815173 1.10375424083 45.105 0.897267406564 0.28751 0.093869658009 rs7252778 465.176 0.00106497142921 SLC7A9 0.0011 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 19:36332622:C:T 19 36332622 T C 0.000430822 0.743542 48.3318 3.6E-12 -0.393822 27.5 NPHS1 missense won 19:36342212:C:T 0.00131765909671 84.1055 0.00075720179929 -0.0216475 44.8866373025 rs199941847 149.706 0.00011314789641 NPHS1 0.0017 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 19:38989881:A:G 19 38989881 G A 0.00179001 0.842164 42.7188 6.3E-11 0.165925 23.1 RYR1 missense won 19:39227651_TC_T 0.0019771663309 58.1345 0.00145287519556 0.0142829 39.0042503656 rs545188339 179.743 0.00014763951049 RYR1 0.0034 0.0000 0.0354 0.0042 biochemistry_Creatinine_v2 19:40957316:G:C 19 40957316 C G 0.00387432 0.963758 33.856 5.9E-09 -0.0962655 23.1 BLVRB missense lost rs191810216 0.955400564381 45.0354 0.718235910144 0.10485 0.0172220614043 rs34781214 97.1305 0.00010829316096 BLVRB 0.0000 0.0000 0.0016 0.0000 biochemistry_Creatinine_v2 1:20141060:G:A 1 20141060 A G 0.000993367 0.906668 86.642 1.3E-20 0.302585 38 RNF186 stop_gained won N/A N/A N/A N/A N/A N/A rs746183034 33.5412 0.490582573056 RNF186 0.0029 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 1:86048526:C:G 1 86048526 G C 0.00861489 0.986897 41.4647 1.2E-10 -0.0678198 24.6 CYR61 missense won N/A N/A N/A N/A N/A N/A rs191024636 40.2912 0.933339549025 CYR61 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 1:228558952:T:G 1 228558952 G T 0.00875239 0.847926 44.8679 2.1E-11 0.0740239 25.1 OBSCN missense won N/A N/A N/A N/A N/A N/A 1:228559994:C:T 32.3792 0.00787446813924 OBSCN 0.0014 0.0000 0.0002 0.0000 biochemistry_Creatinine_v2 20:56136474:C:T 20 56136474 T C 0.00224533 0.940215 34.5611 4.1E-09 0.124619 21.8 PCK1 missense lost rs17411842 0.0126475694581 44.5253 0.00981720309124 -0.0181573 27.2246336176 rs2235826 72.3992 0.00045735671881 PCK1 0.0024 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 20:61050522:G:C 20 61050522 C G 0.00707694 0.959274 42.0137 9.1E-11 -0.0749547 25.7 GATA5 missense won rs62196293 0.00588707287207 45.2621 0.00546456557529 0.0129852 35.813845303 rs4809319 59.2597 0.00010224647689 GATA5 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 2:170027153:T:A 2 170027153 A T 0.000618843 0.9154 45.1948 1.8E-11 -0.273398 29.0 LRP2 missense won 2:169987764_AGTGT_A 0.00372131981358 99.3158 0.00169342949169 -0.0241317 39.8489817604 rs13034796 158.581 0.00065401924644 LRP2 0.0025 0.0053 0.0000 0.0000 biochemistry_Creatinine_v2 2:170030642:A:G 2 170030642 G A 7.20329e-05 0.828968 43.9626 3.3E-11 -0.808189 27.5 LRP2 missense lost 2:170029657:C:T 0.0354139571407 114.154 0.013638502656 -0.153464 28.9732010883 2:170029657:C:T 114.154 0.013638502656 LRP2 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 2:170053486:G:A 2 170053486 A G 0.000119281 0.82985 32.1083 1.5E-08 -0.531371 26.7 LRP2 missense lost rs3821129 0.0210001581406 104.886 0.00642868807681 0.0859798 23.4766748992 rs34806803 144.472 0.00024047325184 LRP2 0.0000 0.0000 0.0014 0.0000 biochemistry_Creatinine_v2 3:70014091:G:A 3 70014091 A G 0.00409417 0.961313 45.0582 1.9E-11 0.111571 31 MITF missense won rs2014520 0.00281830128555 62.9304 0.00201790522521 0.0151793 40.4011173863 rs2014520 62.9304 0.00201790522521 MITF 0.0001 0.0000 0.0001 0.0000 biochemistry_Creatinine_v2 3:125879755:C:T 3 125879755 T C 0.00722277 0.908135 37.5504 8.9E-10 -0.0749862 26.1 ALDH1L1 missense lost rs758248233 0.0221004635787 65.8058 0.012611065401 -0.016523 27.2156275944 rs9879085 74.5176 0.010842223876 ALDH1L1 0.0000 0.0000 0.0720 0.0000 biochemistry_Creatinine_v2 4:40428091:C:T 4 40428091 T C 0.00601336 0.956024 45.4587 1.6E-11 0.0885101 29.7 RBM47 missense won N/A N/A N/A N/A N/A N/A rs6855939 43.215 0.00162271203241 RBM47 0.0028 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 5:1212453:G:A 5 1212453 A G 0.00444078 0.972121 129.411 5.5E-30 -0.165764 22.5 SLC6A19 missense won rs2455357 0.00130856441329 150.267 0.0011269449 0.0290655 120.217693645 5:692984:C:CCGG 211.443 0.00024679781604 SLC6A19 0.0054 0.0035 0.0000 0.0000 biochemistry_Creatinine_v2 5:131008584:C:T 5 131008584 T C 0.00346055 0.917733 52.3472 4.7E-13 0.125578 32 FNIP1 missense lost rs550880018 0.996068374413 57.4199 0.908071773184 -0.163884 0.000202690210698 rs11242113 90.373 0.00067589080441 FNIP1 0.0006 0.0184 0.0000 0.0000 biochemistry_Creatinine_v2 6:43267663:G:A 6 43267663 A G 0.000913041 0.927902 151.872 6.8E-35 0.416301 25.6 SLC22A7 missense won N/A N/A N/A N/A N/A N/A rs146734164 96.7926 0.568775405584 SLC22A7 0.0020 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 6:43268950:C:T 6 43268950 T C 0.000364676 0.878849 70.4165 4.8E-17 0.470737 26.1 SLC22A7 missense lost 6:43267663:G:A 0.835892362103 151.872 0.387567257401 0.416301 0.517517404702 6:43267663:G:A 151.872 0.387567257401 SLC22A7 0.0001 0.0000 0.0696 0.0572 biochemistry_Creatinine_v2 6:43401090:C:T 6 43401090 T C 0.000472914 0.881475 72.6099 1.6E-17 0.40647 25.4 ABCC10 missense lost 6:43267663:G:A 1.06595381209 151.872 0.509631793225 0.416301 0.0764602538361 rs1317840 230.067 0.000122921569 ABCC10 0.0000 0.0000 0.0009 0.0029 biochemistry_Creatinine_v2 6:51889483:G:A 6 51889483 A G 0.00864872 0.960875 107.175 4.1E-25 -0.112415 23.2 PKHD1 missense won rs2580009 0.00345968884829 111.311 0.003331136656 -0.020824 94.9379138337 rs9370040 123.122 0.00252217897369 PKHD1 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 6:131897807:G:A 6 131897807 A G 0.00157347 0.952346 45.9538 1.2E-11 0.165431 22.8 ARG1 missense lost rs755527581 0.992778120057 48.935 0.932296458025 -0.170439 0.000601359869221 rs755527581 48.935 0.932296458025 ARG1 0.0004 0.0710 0.0000 0.0000 biochemistry_Creatinine_v2 6:160645750:C:T 6 160645750 T C 6.28261e-05 0.88262 33.8371 6.0E-09 0.738786 24.1 SLC22A2 missense lost 6:160668186:CCT:C 0.0054371134589 492.209 0.00037377648889 0.0682157 29.0309982179 rs9766047 526.124 0.00033466677721 SLC22A2 0.0000 0.0000 0.0000 0.0018 biochemistry_Creatinine_v2 6:160668329:A:C 6 160668329 C A 0.000624269 0.943366 34.9093 3.5E-09 0.238528 26.0 SLC22A2 missense lost 6:160681393:A:G 0.04458149646 411.651 0.003780651169 0.0585766 21.7238786792 6:160681393:A:G 411.651 0.003780651169 SLC22A2 0.0092 0.0369 0.0001 0.0000 biochemistry_Creatinine_v2 6:160679656:A:AT 6 160679656 AT A 0.0012579 0.885621 328.041 2.6E-73 0.525088 33 SLC22A2 frameshift won rs9766047 0.0116256454997 526.124 0.007248649321 -0.0668519 261.114426902 rs9766047 526.124 0.007248649321 N/A N/A N/A N/A N/A biochemistry_Creatinine_v2 9:104189856:C:G 9 104189856 G C 0.00547262 0.912482 40.6288 1.8E-10 -0.0890942 27.2 ALDOB missense won N/A N/A N/A N/A N/A N/A rs183342753 39.4299 0.688903320004 ALDOB 0.0000 0.0000 0.0000 0.0000 biochemistry_Creatinine_v2 9:117354865:A:C 9 117354865 C A 0.00516904 0.933193 40.6474 1.8E-10 0.087051 22.7 ATP6V1G1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ATP6V1G1 0.0000 0.1039 0.0000 0.0000 biochemistry_Creatinine_v2 9:140127344:C:T 9 140127344 T C 0.000331505 0.901798 35.0187 3.3E-09 0.345229 25.2 SLC34A3 missense won 9:140145505_C_G 0.00364622187831 35.1865 0.00362883350404 0.0220882 30.9172508232 9:140130606:A:T 73.8905 0.00163851705796 SLC34A3 0.0006 0.0000 0.0111 0.0000 biochemistry_Creatinine_v2 9:140127380:G:A 9 140127380 A G 0.000504562 0.860092 61.8783 3.7E-15 0.352503 24.7 SLC34A3 splice_donor won 9:140130606:A:T 0.0028195382672 73.8905 0.00236117274561 -0.0234999 55.4813763667 9:140130606:A:T 73.8905 0.00236117274561 SLC34A3 0.0003 0.0005 0.2399 0.9081 biochemistry_Creatinine_v2 9:140127675:C:T 9 140127675 T C 0.0012844 0.640597 75.4264 3.8E-18 0.304248 21.8 SLC34A3 missense won N/A N/A N/A N/A N/A N/A rs11103387 59.5835 0.00011613941824 SLC34A3 0.0026 0.0004 0.0000 0.0000 biochemistry_Creatinine_v2 9:140130522:G:A 9 140130522 A G 0.00138871 0.964105 34.4348 4.4E-09 0.163769 27.8 SLC34A3 missense lost 9:140087697_A_G 0.00512141498597 57.0565 0.00309088185849 -0.0169054 29.6825665687 9:140087697_A_G 57.0565 0.00309088185849 SLC34A3 0.0000 0.0000 0.0001 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_CystatinC_v2 11:116701354:G:A 11 116701354 A G 0.00223009 0.92045 38.9993 4.2E-10 0.132357 31 APOC3 splice_donor won N/A N/A N/A N/A N/A N/A rs530885291 36.5912 0.659852409969 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_CystatinC_v2 12:111856181:G:A 12 111856181 A G 0.0010701 0.940356 104.679 1.4E-24 0.299152 22.1 SH2B3 missense won rs565349424 0.0041188810023 682.83 0.00063143146089 0.0510231 91.673876082 rs565349424 682.83 0.00063143146089 SH2B3 0.0012 0.0000 0.0181 0.0000 biochemistry_CystatinC_v2 12:111885295:G:A 12 111885295 A G 0.000484235 0.861631 41.3574 1.3E-10 0.29564 32 SH2B3 missense won 12:110738448_CT_C 0.00351471538355 109.373 0.00132902535364 -0.0316651 36.599009671 12:111800258:G:A 620.188 0.00018960739204 SH2B3 0.0001 0.0000 0.0001 0.0000 biochemistry_CystatinC_v2 12:111885310:G:A 12 111885310 A G 0.00199984 0.885884 168.658 1.5E-38 0.288276 32 SH2B3 missense lost rs551014092 1.07726134846 191.591 0.948315654225 -0.296945 0.242415650293 rs565349424 682.83 0.00099266584356 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_CystatinC_v2 12:112167753:G:A 12 112167753 A G 0.0055013 0.971607 36.6465 1.4E-09 -0.0809733 25.1 ACAD10 missense lost rs184679457 0.964085800623 37.1973 0.949810074724 0.084553 0.0120340202171 rs7137828 1600.7 0.00485981871376 ACAD10 0.0002 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 12:112184086:G:A 12 112184086 A G 0.00202733 0.911388 59.5741 1.2E-14 0.177292 28.2 ACAD10 missense lost 12:111856181:G:A 0.897199870608 104.679 0.510607426624 0.299152 0.166043109594 rs565349424 682.83 0.00140028633616 ACAD10 0.0001 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 12:112673047:T:A 12 112673047 A T 0.00692997 0.996032 56.0478 7.1E-14 -0.0822722 20.7 HECTD4 missense lost rs112439578 0.939527445532 56.7442 0.927996982276 0.0861473 0.0528512009186 rs7137828 1600.7 0.00669709816164 HECTD4 0.0173 0.0039 0.0000 0.0000 biochemistry_CystatinC_v2 13:96230248:GAT:G 13 96230248 G GAT 5.26829e-05 0.724996 56.7803 4.9E-14 1.1044 35 CLDN10 frameshift won rs12870505 0.000547661816385 161.515 0.00019252950025 -0.032021 54.1538313154 rs7490694 195.261 0.00010347161841 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 15:57730307:C:T 15 57730307 T C 0.000104488 0.946518 41.9815 9.2E-11 0.598855 22.3 CGNL1 missense won rs1908188 0.000766107728231 138.252 0.00023263570576 -0.0231943 39.689679767 rs1908188 138.252 0.00023263570576 CGNL1 0.0005 0.0000 0.2670 0.0000 biochemistry_CystatinC_v2 15:57731228:A:G 15 57731228 G A 0.00060038 0.889538 39.4692 3.3E-10 0.249105 28.6 CGNL1 missense won rs17820551 0.00159613416367 50.7912 0.00124033569856 -0.0166197 36.3784789821 rs4774940 123.944 0.00025929050625 CGNL1 0.0000 0.0000 0.0099 0.0000 biochemistry_CystatinC_v2 15:57836791:G:A 15 57836791 A G 0.0001983 0.936284 40.7946 1.7E-10 0.42929 31 CGNL1 missense won rs17820551 0.000582245391753 50.7912 0.00046764927504 -0.0166197 38.849624528 rs13380261 107.454 0.00018330993664 CGNL1 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 16:1828030:G:A 16 1828030 A G 0.00667407 0.933647 33.791 6.1E-09 0.0662894 23.6 SPSB3 missense lost 16:1838604:C:T 1.03818127609 35.7489 0.981322040689 0.0684905 0.012085572441 16:1838604:C:T 35.7489 0.981322040689 SPSB3 0.0289 0.0035 0.0001 0.0000 biochemistry_CystatinC_v2 16:69727480:A:G 16 69727480 G A 0.00636651 0.948307 49.3425 2.1E-12 -0.0876944 25.5 NFAT5 missense lost rs551972048 0.824981006311 52.4828 0.775618398864 0.0965012 0.415054570553 rs373799343 157.388 0.00116804682289 NFAT5 0.0002 0.0000 0.0001 0.0000 biochemistry_CystatinC_v2 19:33353113:C:CT 19 33353113 CT C 0.000870167 0.926037 34.9402 3.4E-09 -0.207172 29.6 SLC7A9 frameshift lost rs11666241 0.0181230241213 131.419 0.00481834504449 0.0304166 26.1659981301 rs35975406 328.58 0.00130186742596 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 1:3389757:A:G 1 3389757 G A 0.00475333 0.87544 69.1635 9.1E-17 -0.114879 25.5 ARHGEF16 missense won N/A N/A N/A N/A N/A N/A rs559472101 41.7029 0.6565536784 ARHGEF16 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 1:149908526:G:GC 1 149908526 GC G 0.00469228 0.921182 35.0078 3.3E-09 0.0799231 27.2 MTMR11 frameshift lost rs141281255 0.912726768929 35.298 0.905222850624 -0.0830807 0.0697381161706 1:150940625:T:G 238.333 0.00052366830244 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 20:23016854:C:A 20 23016854 A C 0.00176821 0.976393 48.2073 3.8E-12 0.155642 24.7 SSTR4 missense lost rs187530592 1.00979626188 59.586 0.8169628996 -0.196333 0.00115094383573 rs734801 33537.0 0.00012553857936 SSTR4 0.0007 0.0000 0.0009 0.0000 biochemistry_CystatinC_v2 20:23030062:C:T 20 23030062 T C 0.000287355 0.876673 32.6398 1.1E-08 -0.34849 26.1 THBD missense lost rs534057813 0.944165444185 138.933 0.221814624784 0.378052 0.0261745956916 rs734801 33537.0 0.00059002839025 THBD 0.0009 0.0000 0.0002 0.0000 biochemistry_CystatinC_v2 20:23065998:C:T 20 23065998 T C 0.000289241 0.668972 39.229 3.8E-10 -0.385303 28.1 CD93 missense lost 20:23618579:C:T 0.608085516769 10360.2 0.00230252183716 -0.447136 1.90216527235 rs734801 33537.0 0.00035663944801 CD93 0.0001 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 20:23546677:AG:A 20 23546677 A AG 0.000239231 0.853147 76.8859 1.8E-18 -0.587427 22.6 CST9L frameshift lost 20:23618579:C:T 0.549411382587 10360.2 0.004077333316 -0.447136 5.14870959423 rs734801 33537.0 0.00069159532324 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 20:23584368:G:A 20 23584368 A G 0.000159356 0.643215 66.3117 3.8E-16 -0.706844 26.2 CST9 stop_gained lost rs541914247 0.32053190485 517.85 0.041044734025 0.529493 12.4812651981 rs734801 33537.0 0.00032299997284 CST9 0.0000 0.1616 0.0001 0.0000 biochemistry_CystatinC_v2 20:23586242:C:T 20 23586242 T C 0.00223901 0.928574 66.5979 3.3E-16 0.170736 LOW NONE N/A lost 20:23584585_TG_T 0.465613916394 1359.17 0.022814592025 -0.123678 6.7194452668 rs734801 33537.0 0.000627151849 CST9 0.0003 0.0000 0.0048 0.7762 biochemistry_CystatinC_v2 20:23615951:ACACGTGGTTCGGCCCAGCTC:A 20 23615951 A ACACGTGGTTCGGCCCAGCTC 0.000124179 0.850984 1169.14 3.1E-256 -3.05977 27.8 CST3 frameshift won rs3761279 0.0111248053407 33020.4 0.00039389150089 0.411296 935.518259444 rs734801 33537.0 0.00036674548036 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 20:23615958:G:A 20 23615958 A G 6.8339e-05 0.79705 322.289 4.6E-72 -2.20539 23.4 CST3 missense won 20:23692133_GTCA_G 0.00109157934498 3438.16 0.00010232334025 0.111864 301.344554171 20:23692133_GTCA_G 3438.16 0.00010232334025 CST3 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 20:23615971:C:A 20 23615971 A C 8.31936e-05 0.719767 307.957 6.1E-69 -2.14755 35 CST3 stop_gained won rs200668055 0.00290445362216 806.726 0.00110873682529 0.126173 275.658004061 rs4258871 3730.12 0.000220463104 CST3 0.0090 0.0153 0.0000 0.0000 biochemistry_CystatinC_v2 20:23616005:C:A 20 23616005 A C 4.05242e-05 0.905808 450.657 5.2E-100 -3.24466 23.3 CST3 splice_acceptor won rs844911 0.000330900640438 908.738 0.00016409866201 0.0715819 434.410613052 rs844911 908.738 0.00016409866201 CST3 0.8907 0.9876 0.0001 0.0000 biochemistry_CystatinC_v2 20:23618288:C:G 20 23618288 G C 1.66325e-05 0.872324 59.093 1.5E-14 -1.76546 23.4 CST3 missense won rs143920283 0.00751792663457 1093.94 0.00040610713441 0.168268 49.2898241134 rs13041546 2125.88 0.00016601034025 CST3 0.0001 0.0000 0.0030 0.0000 biochemistry_CystatinC_v2 20:23618291:CTG:C 20 23618291 C CTG 2.48502e-05 0.89826 232.646 1.6E-52 -2.98535 24.4 CST3 frameshift won rs73901921 0.000500231138594 712.042 0.00016344088336 0.0974985 222.355726815 rs35339750 833.762 0.00012416422041 N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 20:23618326:G:A 20 23618326 A G 8.53701e-05 0.862385 54.6805 1.4E-13 -0.799589 LOW NONE N/A lost rs186678239 0.239150855351 288.234 0.045369 0.371254 14.2765209931 rs734801 33537.0 0.00025425578116 CST3 0.0001 0.0000 0.9636 0.0000 biochemistry_CystatinC_v2 20:23618327:C:A 20 23618327 A C 8.53701e-05 0.862385 54.6805 1.4E-13 -0.799589 22.6 CST3 missense lost 20:23618326:G:A 1.0 54.6805 1.0 -0.799589 0.0 rs734801 33537.0 0.00025425578116 CST3 0.0000 0.0000 0.0099 0.0000 biochemistry_CystatinC_v2 20:25485592:C:T 20 25485592 T C 0.000123266 0.718822 86.3922 1.5E-20 -0.902365 23.6 NINL missense lost rs555902140 1.75664964781 594.524 0.255264426169 1.30273 9.14689871023 rs113422114 14124.8 0.00019522237284 NINL 0.0000 0.0000 0.0001 0.0000 biochemistry_CystatinC_v2 20:30610469:G:T 20 30610469 T G 3.95211e-05 0.736349 37.5955 8.7E-10 -1.01466 26.3 CCM2L missense won 20:30407459:G:A 0.000611690707033 111.159 0.00020688219556 -0.678968 35.7588443018 20:30407459:G:A 111.159 0.00020688219556 CCM2L 0.0898 0.0045 0.0001 0.0000 biochemistry_CystatinC_v2 20:52788189:C:T 20 52788189 T C 0.00919912 0.955744 30.3004 3.7E-08 0.0542322 23.2 CYP24A1 missense lost rs11481757 0.0974752555363 145.142 0.020349307801 -0.0256708 14.3337468267 rs35870583 341.678 0.00188340376324 CYP24A1 0.0025 0.0000 0.0129 0.0000 biochemistry_CystatinC_v2 20:61050522:G:C 20 61050522 C G 0.00708411 0.959274 49.0329 2.5E-12 -0.0758911 25.7 GATA5 missense won N/A N/A N/A N/A N/A N/A rs2379120 44.0073 0.013876604401 GATA5 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 21:35468605:G:A 21 35468605 A G 0.00790534 0.956672 32.473 1.2E-08 0.0651498 27.9 SLC5A3 missense lost rs538215600 0.576380500372 35.1736 0.5321264809 -0.0920811 1.88297785178 21:35357633_ACAC_A 187.208 0.028145095225 SLC5A3 0.0003 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 2:39241107:G:A 2 39241107 A G 0.00969015 0.95699 65.1941 6.8E-16 0.0791619 23.0 SOS1 missense won N/A N/A N/A N/A N/A N/A rs115393289 53.5661 0.906503931025 SOS1 0.0005 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 2:120776742:C:T 2 120776742 T C 0.00518327 0.879067 38.9539 4.3E-10 0.0906076 23.1 EPB41L5 missense won rs11123537 0.0114211105439 53.7158 0.00828241966084 0.0148348 31.0728216887 rs4849902 100.981 0.00019773703161 EPB41L5 0.0001 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 2:170027153:T:A 2 170027153 A T 0.000617953 0.9154 30.1679 4.0E-08 -0.21654 29.0 LRP2 missense lost rs9789747 0.0027998490842 34.6216 0.00243967832761 0.0159365 27.0597811693 rs6721930 63.8771 0.000239909121 LRP2 0.0025 0.0053 0.0000 0.0000 biochemistry_CystatinC_v2 2:170030642:A:G 2 170030642 G A 7.20113e-05 0.828968 37.0851 1.1E-09 -0.699008 27.5 LRP2 missense lost 2:170029657:C:T 0.0302196370893 82.2167 0.013631029504 -0.124305 25.3122018421 2:170029657:C:T 82.2167 0.013631029504 LRP2 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 3:70014091:G:A 3 70014091 A G 0.00409483 0.961313 68.6444 1.2E-16 0.132257 31 MITF missense won rs2014520 0.00253828596878 86.5329 0.00201355920529 0.0177188 61.9018364839 rs2014520 86.5329 0.00201355920529 MITF 0.0001 0.0000 0.0001 0.0000 biochemistry_CystatinC_v2 4:40428091:C:T 4 40428091 T C 0.00601363 0.956024 37.3817 9.7E-10 0.0750819 29.7 RBM47 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A RBM47 0.0028 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 5:1212453:G:A 5 1212453 A G 0.00444116 0.972121 74.0004 7.8E-18 -0.115145 22.5 SLC6A19 missense lost rs184695735 0.768537377709 79.8746 0.712017003721 0.113853 1.12570187772 5:692887:T:C 140.005 0.00030583713924 SLC6A19 0.0054 0.0035 0.0000 0.0000 biochemistry_CystatinC_v2 5:131008584:C:T 5 131008584 T C 0.00346237 0.917733 55.3646 1.0E-13 0.129806 32 FNIP1 missense won N/A N/A N/A N/A N/A N/A rs74667082 50.8867 0.953938983204 FNIP1 0.0006 0.0184 0.0000 0.0000 biochemistry_CystatinC_v2 5:176813433:C:T 5 176813433 T C 0.00429873 0.934389 30.9654 2.6E-08 0.0751354 28.6 SLC34A1 missense lost 5:176806636:C:T 0.197560808462 672.721 0.00909373939321 0.0527534 9.55606325614 5:176798040:T:G 701.084 0.00780008678761 SLC34A1 0.0333 0.0031 0.0001 0.0000 biochemistry_CystatinC_v2 6:51889483:G:A 6 51889483 A G 0.00864427 0.960875 103.617 2.5E-24 -0.104248 23.2 PKHD1 missense won rs2580009 0.0048969283876 152.305 0.00333150604864 -0.0237235 89.6225724738 rs12212034 163.271 0.00252441934096 PKHD1 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 6:82461326:ATCT:A 6 82461326 A ATCT 4.64177e-05 0.673105 59.4411 1.3E-14 -1.27281 20.6 FAM46A inframe_deletion won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_CystatinC_v2 9:104189856:C:G 9 104189856 G C 0.00547597 0.912482 32.8021 1.0E-08 -0.0761969 27.2 ALDOB missense won rs62576023 0.000119057018655 33.1379 0.00011785056481 0.0139872 32.0901765564 rs62576024 33.1666 0.00011092723684 ALDOB 0.0000 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 9:139848356:G:A 9 139848356 A G 0.00025006 0.736539 30.2894 3.7E-08 0.353353 20.4 LCN12 missense lost 9:140127589:TGGGCTGGGGCTGCAGTGGCAGCCCCAGCCC:T 1.05264349291 57.5046 0.5544589444 0.544427 0.0204506904184 9:140127589:TGGGCTGGGGCTGCAGTGGCAGCCCCAGCCC:T 57.5046 0.5544589444 LCN12 0.1306 0.0000 0.0000 0.0000 biochemistry_CystatinC_v2 9:140127344:C:T 9 140127344 T C 0.000331368 0.901798 38.2302 6.3E-10 0.33005 25.2 SLC34A3 missense won 9:140130606:A:T 0.00293069266223 68.4302 0.00163730292496 -0.0219126 34.2029905215 9:140130606:A:T 68.4302 0.00163730292496 SLC34A3 0.0006 0.0000 0.0111 0.0000 biochemistry_CystatinC_v2 9:140127380:G:A 9 140127380 A G 0.000504357 0.860092 60.0093 9.4E-15 0.353527 24.7 SLC34A3 splice_donor won 9:140130606:A:T 0.00269051363479 68.4302 0.00235942376121 -0.0219126 53.9453716971 9:140130606:A:T 68.4302 0.00235942376121 SLC34A3 0.0003 0.0005 0.2399 0.9081 biochemistry_CystatinC_v2 9:140127675:C:T 9 140127675 T C 0.00128463 0.640597 105.443 9.8E-25 0.342299 21.8 SLC34A3 missense won N/A N/A N/A N/A N/A N/A 9:139649761:C:T 63.7994 0.656929702144 SLC34A3 0.0026 0.0004 0.0000 0.0000 biochemistry_CystatinC_v2 9:140130522:G:A 9 140130522 A G 0.00138706 0.964105 36.5171 1.5E-09 0.162937 27.8 SLC34A3 missense lost 9:140130653:A:T 0.998959047928 36.5728 0.997437643524 0.163587 9.89746297934e-06 9:140113861_C_T 50.4925 0.00308231494596 SLC34A3 0.0000 0.0000 0.0001 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_DirectBilirubin_v2 10:101591826:C:T 10 101591826 T C 0.000721325 0.692767 31.1368 2.4E-08 0.241383 38 ABCC2 stop_gained lost rs4148394 0.00185189778501 40.0367 0.00144023286016 -0.0145106 28.5145998726 rs2756102 83.0945 0.00029434206096 ABCC2 0.0005 0.0000 0.0033 0.0000 biochemistry_DirectBilirubin_v2 12:20876168:C:T 12 20876168 T C 0.00701934 0.931822 31.9559 1.6E-08 -0.0689678 27.1 SLCO1C1 missense lost rs144146640 1.13352366978 117.403 0.308533589764 0.125935 0.133649085053 rs77289848 2844.55 0.00016874269801 SLCO1C1 0.0000 0.0000 0.0002 0.0386 biochemistry_DirectBilirubin_v2 12:21008080:T:TAATTG 12 21008080 TAATTG T 0.00249774 0.855625 313.794 3.3E-70 0.384278 23.9 LST3 frameshift lost rs189206203 0.753620151829 340.056 0.695419230724 -0.360476 5.45819093987 12:21331599:T:C 1109.62 0.00323754172036 N/A N/A N/A N/A N/A biochemistry_DirectBilirubin_v2 12:21015424:C:G 12 21015424 G C 0.000431799 0.863739 43.0807 5.3E-11 0.346433 24.2 LST3 missense won rs2090273 0.0206234286974 275.146 0.00322909199001 0.0541475 31.5956541056 12:20953761_GT_G 980.043 0.00059817419776 SLCO1B3 0.0010 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 12:21032543:G:A 12 21032543 A G 0.0007853 0.862134 131.858 1.6E-30 0.427707 25.2 LST3 missense won rs67981690 0.0967639705792 3512.57 0.00363241263025 -0.171921 62.5832109591 rs4149083 4043.0 0.00286327729216 SLCO1B3 0.0000 0.0000 0.0000 0.1169 biochemistry_DirectBilirubin_v2 12:21200143:T:G 12 21200143 G T 0.000392105 0.883466 62.7526 2.3E-15 0.405982 21.9 LST3 missense lost rs548489043 0.873300492818 93.4825 0.586226047716 -0.523138 0.26917929226 rs4149083 4043.0 0.00119385452484 SLCO1B7 0.0002 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 12:21375289:C:T 12 21375289 T C 0.000643328 0.929363 120.285 5.5E-28 0.455944 42 SLCO1B1 stop_gained lost rs73079474 0.464960291955 1530.66 0.0365383225 -0.302973 12.1728846052 rs4149083 4043.0 0.003075257025 SLCO1B1 0.0000 0.0000 0.0024 0.1176 biochemistry_DirectBilirubin_v2 16:88782205:G:C 16 88782205 C G 0.00149143 0.954236 34.9501 3.4E-09 0.159293 23.3 PIEZO1 missense lost 16:88798919:G:T 1.0154768898 35.9678 0.9867442225 0.162139 0.00207689426488 rs861400 96.5742 0.00160862759929 PIEZO1 0.0331 0.0000 0.0001 0.0000 biochemistry_DirectBilirubin_v2 16:88786073:G:A 16 88786073 A G 3.5634e-05 0.839812 30.3606 3.6E-08 0.935094 32 PIEZO1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PIEZO1 0.0081 0.0000 0.0002 0.0000 biochemistry_DirectBilirubin_v2 16:88798919:G:T 16 88798919 T G 0.00147754 0.936239 35.9678 2.0E-09 0.162139 22.4 PIEZO1 missense won rs837756 0.00464430124367 95.8633 0.00174253648969 0.0199199 31.2324981546 rs861400 96.5742 0.00166682759824 PIEZO1 0.0076 0.0000 0.0001 0.0000 biochemistry_DirectBilirubin_v2 2:21228891:CA:C 2 21228891 C CA 0.000157847 0.642863 46.3317 1.0E-11 0.60071 25.3 APOB frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_DirectBilirubin_v2 2:234181677:G:A 2 234181677 A G 0.00167028 0.782133 46.327 1.0E-11 -0.172788 23.4 ATG16L1 missense lost rs28946889 0.954296974229 13883.9 0.00318424332681 0.257895 0.024760700122 rs1976391 79432.9 0.00051223910929 ATG16L1 0.0000 0.0000 0.0003 0.0000 biochemistry_DirectBilirubin_v2 2:234229468:C:T 2 234229468 T C 0.00327481 0.910413 85.8303 2.0E-20 -0.15366 25.9 SAG missense lost 2:234649573_GT_G 0.913833909281 49923.4 0.00157109969641 -0.413495 0.166571010701 rs1976391 79432.9 0.00095904799225 SAG 0.0003 0.0000 0.0093 0.0104 biochemistry_DirectBilirubin_v2 2:234231596:C:G 2 234231596 G C 0.000120981 0.704851 32.594 1.1E-08 0.543815 25.7 SAG missense lost rs191296211 0.6575200285 379.04 0.056540755089 -0.50138 1.1658174483 rs1976391 79432.9 0.00012260247076 SAG 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234237188:C:T 2 234237188 T C 0.000220243 0.773074 32.5254 1.2E-08 -0.437147 35 SAG stop_gained lost 2:234649573_GT_G 0.246454960954 49923.4 0.00016056691225 -0.413495 8.24747717413 rs7576166 54324.6 0.00012972982201 SAG 0.0001 0.0000 0.0002 0.0000 biochemistry_DirectBilirubin_v2 2:234357944:C:T 2 234357944 T C 0.00156005 0.969618 112.215 3.2E-26 -0.245047 26.9 DGKD missense lost rs528273505 0.982994623701 119.681 0.921672961444 0.268936 0.00818238404156 rs1976391 79432.9 0.00081380684529 DGKD 0.0001 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234358615:T:G 2 234358615 G T 0.00387573 0.979854 97.3128 5.9E-23 -0.144459 LOW NONE N/A lost rs76074357 1.01013599514 102.283 0.961050830224 0.153895 0.00248685280529 rs1976391 79432.9 0.00061808920996 DGKD 0.5808 0.0257 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234371365:C:T 2 234371365 T C 0.000187073 0.825777 51.6116 6.8E-13 0.526397 24.3 DGKD missense lost rs773038058 0.986167458646 59.0517 0.861917276025 -0.581982 0.00248605473259 rs1976391 79432.9 0.00026703808569 DGKD 0.0000 0.0000 0.0004 0.0004 biochemistry_DirectBilirubin_v2 2:234377185:C:T 2 234377185 T C 0.000414455 0.762864 83.4066 6.7E-20 0.470771 33 DGKD missense lost 2:234664586_ATC_A 0.449324629929 78816.4 0.00047549291364 -0.547902 9.06554707108 rs1976391 79432.9 0.00046128730176 DGKD 0.0000 0.0000 0.0000 0.0076 biochemistry_DirectBilirubin_v2 2:234398065:G:A 2 234398065 A G 0.000410865 0.903525 55.7109 8.4E-14 0.352918 23.6 USP40 missense lost rs6744284 1.00992716019 62542.6 0.00089961004225 -0.499606 0.00136578572154 rs1976391 79432.9 0.00062767786225 USP40 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234405421:C:T 2 234405421 T C 0.000272262 0.83379 46.2918 1.0E-11 0.420355 29.2 USP40 missense lost rs192958236 0.881233128579 856.223 0.047643975625 -0.411418 0.173722262961 rs1976391 79432.9 0.00046628356096 USP40 0.0001 0.0000 0.0000 0.0035 biochemistry_DirectBilirubin_v2 2:234432123:G:A 2 234432123 A G 0.000357019 0.908655 55.4338 9.7E-14 0.371143 23.5 USP40 missense lost rs192182758 0.791794098047 57.2211 0.767062424041 -0.41397 0.672846666915 rs1976391 79432.9 0.00046543316121 USP40 0.0000 0.0000 0.0062 0.0000 biochemistry_DirectBilirubin_v2 2:234463169:C:A 2 234463169 A C 0.00105043 0.760536 54.1607 1.8E-13 -0.247944 29.8 USP40 missense lost 2:234668570:C:T 0.492882107454 79275.0 0.00033673718016 0.545956 4.8078912501 rs1976391 79432.9 0.00033444728641 USP40 0.0055 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234526784:C:T 2 234526784 T C 0.00594777 0.977585 49.2182 2.3E-12 -0.0838007 22.4 UGT1A8 missense lost rs12469671 0.987518671745 2937.33 0.016546963225 0.116704 0.0019289030768 rs1976391 79432.9 0.00262326303684 UGT1A8 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234545341:T:A 2 234545341 A T 0.000737657 0.865263 41.4391 1.2E-10 -0.230697 22.8 UGT1A10 missense lost 2:234580842:C:T 0.933084404724 73.5203 0.525925192849 -0.223884 0.0480080815852 rs1976391 79432.9 0.00034189489216 UGT1A8 0.0000 0.0000 0.0028 0.0000 biochemistry_DirectBilirubin_v2 2:234545792:G:A 2 234545792 A G 0.00088838 0.93278 124.806 5.6E-29 0.359751 35 UGT1A10 stop_gained lost rs929596 0.992138251572 60643.8 0.00204183785689 -0.49944 0.00193609190944 rs1976391 79432.9 0.00152975636641 UGT1A8 0.0037 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234580842:C:T 2 234580842 T C 0.0014769 0.850006 73.5203 1.0E-17 -0.223884 20.7 UGT1A8 missense lost rs528831440 0.940378655462 226.507 0.305230835529 0.253506 0.0673591907985 rs1976391 79432.9 0.00062451009604 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234581154:A:AAT 2 234581154 AAT A 0.000100331 0.772213 29.8674 4.6E-08 0.575352 23.0 UGT1A8 frameshift lost 2:234664586_ATC_A 0.53585699542 78816.4 0.0002030625 -0.547902 2.14483535146 rs1976391 79432.9 0.00019803807076 N/A N/A N/A N/A N/A biochemistry_DirectBilirubin_v2 2:234581395:T:C 2 234581395 C T 0.000141536 0.678817 33.6085 6.7E-09 0.523032 25.3 UGT1A8 missense lost rs542800224 1.07759309618 553.053 0.065484298201 -0.658201 0.0487142843081 rs1976391 79432.9 0.00014489659129 UGT1A9 0.0000 0.0000 0.0000 0.0007 biochemistry_DirectBilirubin_v2 2:234591185:T:C 2 234591185 C T 0.0006092 0.882847 94.8555 2.0E-22 0.387897 23.2 UGT1A7 missense lost 2:234604081_CTTT_C 0.979240188036 57486.6 0.00161579076961 -0.523173 0.0103274427812 rs1976391 79432.9 0.00108632864025 UGT1A9 0.0061 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234591411:C:A 2 234591411 A C 0.00470032 0.910772 376.98 5.7E-84 -0.266704 22.5 UGT1A7 missense lost rs757254535 0.961483725151 5989.59 0.060515016004 0.294313 0.14257193042 rs1976391 79432.9 0.00191621560516 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234628292:A:C 2 234628292 C A 0.00371534 0.952625 218.817 1.6E-49 -0.227841 21.6 UGT1A4 missense lost 2:234644514_CAG_C 0.876676962061 3042.84 0.063043677225 0.230569 0.887604675446 rs1976391 79432.9 0.00175081991184 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234638011:A:C 2 234638011 C A 0.000204664 0.687546 31.2114 2.3E-08 0.435079 21.7 UGT1A3 missense lost rs113744273 0.810531462525 412.62 0.061310216881 -0.397698 0.310273945633 rs1976391 79432.9 0.000275593201 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234669457:T:A 2 234669457 A T 8.05239e-05 0.938996 35.3934 2.7E-09 0.647493 25.2 UGT1A1 missense lost 2:234929528_GT_G 0.734043423668 76.6628 0.338890472449 -0.61125 0.726157195534 rs1976391 79432.9 0.00013718734129 UGT1A9 0.0012 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234669768:A:T 2 234669768 T A 0.000173816 0.704405 74.8248 5.1E-18 0.726929 25.4 UGT1A1 missense lost rs565790231 0.391787882442 223.238 0.1313192644 -0.433759 10.4701334921 rs1976391 79432.9 0.00019094817856 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234676526:C:T 2 234676526 T C 0.00032328 0.922925 46.6691 8.4E-12 0.347528 23.0 UGT1A10 missense lost rs143373661 1.02061856819 8057.82 0.00591119558649 -0.403549 0.00490956939264 rs1976391 79432.9 0.00050374211364 UGT1A9 0.0000 0.0075 0.0141 0.0000 biochemistry_DirectBilirubin_v2 2:234676880:C:T 2 234676880 T C 6.88829e-05 0.910146 45.5965 1.5E-11 0.781044 24.4 UGT1A10 missense lost rs554459516 0.678698870105 71.4255 0.4332667329 -0.76135 1.4150977333 rs1976391 79432.9 0.00016600518649 UGT1A9 0.0009 0.0004 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234680925:T:C 2 234680925 C T 0.00013726 0.890015 36.0232 1.9E-09 0.459581 23.6 UGT1A10 missense lost rs149780205 0.542241596007 3757.34 0.005198698404 -0.377655 2.5036298226 rs1976391 79432.9 0.00022870210441 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234680927:C:T 2 234680927 T C 0.000220032 0.867142 32.8485 1.0E-08 0.375801 34 UGT1A10 missense lost rs139257330 0.880884264226 4954.28 0.00584055135225 -0.372217 0.124021750202 rs1976391 79432.9 0.00030852219904 UGT1A9 0.0186 0.0020 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234688427:A:G 2 234688427 G A 0.00117776 0.959465 155.103 1.3E-35 0.343316 23.8 MROH2A missense lost rs112132688 0.993230859751 65295.9 0.00235930718529 -0.509411 0.00178279282145 rs1976391 79432.9 0.00212657477904 MROH2A 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234698550:C:T 2 234698550 T C 0.0065535 0.858137 341.353 3.2E-76 -0.223965 25.7 MROH2A missense lost rs142854795 0.748980369492 948.502 0.2695478724 0.228309 6.18099150351 rs1976391 79432.9 0.00251992956121 MROH2A 0.0012 0.0000 0.0004 0.0000 biochemistry_DirectBilirubin_v2 2:234701492:A:G 2 234701492 G A 0.000775386 0.90022 45.4301 1.6E-11 0.237054 24.5 MROH2A missense lost rs200973045 0.997718245345 45843.9 0.00098871255844 -0.414706 5.91994256067e-05 rs1976391 79432.9 0.00034831130161 MROH2A 0.0473 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234702346:A:G 2 234702346 G A 0.00618499 0.936211 55.9986 7.3E-14 -0.0918513 20.3 MROH2A missense lost 2:234315394:A:C 1.02717838069 1180.08 0.048742925284 -0.133871 0.0102028588924 rs1976391 79432.9 0.00170001185344 MROH2A 0.1689 0.0000 0.0005 0.0000 biochemistry_DirectBilirubin_v2 2:234704848:C:T 2 234704848 T C 0.000336311 0.859269 50.6765 1.1E-12 0.401438 29.4 MROH2A missense lost rs112233788 0.984157556717 46285.6 0.00107752001536 -0.5094 0.00320517469548 rs1976391 79432.9 0.00045866647225 MROH2A 0.0036 0.0005 0.0203 0.0000 biochemistry_DirectBilirubin_v2 2:234712127:G:T 2 234712127 T G 0.00111302 0.796816 68.869 1.1E-16 -0.257828 24.3 MROH2A missense lost rs192706104 0.646378624364 157.928 0.281871799056 0.215954 2.64629904835 rs1976391 79432.9 0.00047108097936 MROH2A 0.0000 0.0000 0.0000 0.0156 biochemistry_DirectBilirubin_v2 2:234725427:C:T 2 234725427 T C 0.00693513 0.970682 155.222 1.3E-35 -0.135716 22.0 MROH2A missense lost rs77349740 0.979745666853 1811.66 0.083944052361 0.210906 0.0160827807337 rs1976391 79432.9 0.00209893175881 MROH2A 0.0000 0.1297 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234725513:C:CCA 2 234725513 CCA C 0.00178763 0.881263 38.9412 4.4E-10 -0.143882 24.0 MROH2A frameshift lost 2:234665659:T:G 0.852001695501 50336.5 0.00065912346756 0.413946 0.230646280471 rs1976391 79432.9 0.00029284450129 N/A N/A N/A N/A N/A biochemistry_DirectBilirubin_v2 2:234737414:G:A 2 234737414 A G 0.000285382 0.868625 30.8736 2.8E-08 -0.332714 25.1 MROH2A missense lost 2:234590479:A:T 1.03122600251 35.7011 0.891783701649 -0.360656 0.0074106699546 rs1976391 79432.9 0.000127103076 MROH2A 0.0000 0.0000 0.0000 0.0001 biochemistry_DirectBilirubin_v2 2:234737636:A:G 2 234737636 G A 0.000574861 0.924111 86.7389 1.2E-20 0.366828 22.5 MROH2A missense lost rs28900373 1.00021106895 6730.48 0.012890196225 -0.421122 9.65954752734e-07 rs1976391 79432.9 0.00084313575424 MROH2A 0.0011 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234741266:C:G 2 234741266 G C 0.00130316 0.936858 40.929 1.6E-10 -0.166637 22.7 MROH2A missense lost rs7597496 0.973981458963 49821.2 0.00080014305424 -0.413256 0.00701847590937 rs1976391 79432.9 0.000447787921 MROH2A 0.0021 0.0000 0.0138 0.0462 biochemistry_DirectBilirubin_v2 2:234851262:A:G 2 234851262 G A 0.000236807 0.738988 62.4911 2.7E-15 0.548167 24.3 TRPM8 missense lost rs180688822 0.968394241168 147.973 0.408966645025 -0.887343 0.0158575659539 rs1976391 79432.9 0.00030503670409 TRPM8 0.0000 0.0061 0.2138 0.0000 biochemistry_DirectBilirubin_v2 2:234878910:C:T 2 234878910 T C 0.00166865 0.961959 46.5855 8.8E-12 0.161915 25.9 TRPM8 missense lost rs2602374 0.977523948815 49772.3 0.00091493545441 -0.446644 0.00595049459255 rs1976391 79432.9 0.00101464546225 TRPM8 0.0000 0.0000 0.0003 0.0000 biochemistry_DirectBilirubin_v2 2:234891850:G:A 2 234891850 A G 0.00374229 0.972335 51.7265 6.4E-13 0.110538 24.8 TRPM8 missense lost rs17862873 0.971381003005 55180.8 0.00091057287049 -0.480784 0.0107459355724 rs1976391 79432.9 0.00049322635569 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 2:234915578:C:T 2 234915578 T C 0.000348721 0.809807 29.8035 4.8E-08 0.311687 22.2 TRPM8 missense lost rs17862873 1.01109003523 55180.8 0.00054609613969 -0.480784 0.000911328416385 rs1976391 79432.9 0.00043306858609 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 3:119531656:C:G 3 119531656 G C 0.000154045 0.925744 44.4719 2.6E-11 0.552054 23.4 NR1I2 missense won N/A N/A N/A N/A N/A N/A 3:119344060:T:C 34.0679 0.748520859241 NR1I2 0.5027 0.0000 0.0045 0.0000 biochemistry_DirectBilirubin_v2 4:74274363:A:G 4 74274363 G A 0.000823193 0.878554 34.5634 4.1E-09 0.215875 24.7 ALB missense lost rs188611325 0.697961281532 39.7596 0.606744407844 -0.274018 0.935967882456 rs188611325 39.7596 0.606744407844 ALB 0.0000 0.0000 0.0000 0.0000 biochemistry_DirectBilirubin_v2 4:74275118:G:A 4 74275118 A G 2.42825e-05 0.687244 55.8881 7.7E-14 1.56082 22.8 ALB missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ALB 0.1193 0.0285 0.0001 0.0000 biochemistry_DirectBilirubin_v2 8:41575677:G:A 8 41575677 A G 0.00139785 0.91167 36.5408 1.5E-09 0.157022 29.2 ANK1 missense won rs534561583 0.00105327640189 40.5505 0.00094912670241 0.0142271 34.2074812311 rs4737010 143.597 0.00017130883225 ANK1 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_GammaGlutamyltransferase_v2 10:52573772:C:T 10 52573772 T C 0.00987364 0.962839 85.0658 2.9E-20 0.0891211 23.4 A1CF missense won rs10994600 0.0251944928848 185.402 0.011559690256 -0.0264324 60.2043866946 rs10994600 185.402 0.011559690256 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 10:102740060:C:T 10 102740060 T C 0.0014029 0.958281 62.3917 2.8E-15 -0.212451 22.3 SEMA4G missense won rs1408343 0.00448099427087 75.9825 0.00367949001744 0.0192169 54.3182474674 10:101523072_CA_C 148.706 0.00011494412944 SEMA4G 0.0004 0.0000 0.0003 0.0290 biochemistry_GammaGlutamyltransferase_v2 11:47290147:G:A 11 47290147 A G 0.000653574 0.910265 41.9457 9.4E-11 0.268847 33 NR1H3 missense lost rs566486969 0.882635699691 42.5938 0.869205665344 -0.263824 0.153598069707 rs3972616 112.051 0.00056982941521 NR1H3 0.0012 0.0004 0.0029 0.0000 biochemistry_GammaGlutamyltransferase_v2 12:121416828:T:A 12 121416828 A T 6.00137e-05 0.949143 38.3061 6.0E-10 0.858197 26.0 HNF1A missense won rs67075643 0.006117238005 1023.92 0.00022885335841 -0.0773444 32.5483748523 rs66627474 1504.01 0.00011761836304 HNF1A 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 12:121570899:G:T 12 121570899 T G 0.00908554 0.917804 34.4473 4.4E-09 -0.0575721 31 P2RX7 splice_donor lost 12:121416650:A:C 1.01959935978 3854.72 0.00911154247936 -0.127313 0.00327607596296 rs9738226 4517.32 0.00725667163321 P2RX7 0.0017 0.0000 0.0354 0.9917 biochemistry_GammaGlutamyltransferase_v2 13:45970147:A:G 13 45970147 G A 0.00632665 0.912642 30.6622 3.1E-08 0.0661967 25.5 SLC25A30 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SLC25A30 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 14:103342015:C:T 14 103342015 T C 0.00262266 0.920338 37.6969 8.3E-10 0.116329 24.9 TRAF3 missense lost rs189571291 0.946990727915 43.6301 0.8182107025 -0.127572 0.0272079577429 rs11624282 3654.11 0.00577651681156 TRAF3 0.0001 0.0000 0.0000 0.0022 biochemistry_GammaGlutamyltransferase_v2 14:103568956:C:T 14 103568956 T C 0.00141871 0.938409 34.5211 4.2E-09 -0.151151 23.6 EXOC3L4 missense lost rs2274685 0.110414671946 3035.1 0.001255851844 -0.107354 15.3909081787 rs11624282 3654.11 0.00049531173136 EXOC3L4 0.0017 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 14:103570385:T:C 14 103570385 C T 0.000185552 0.766741 34.5238 4.2E-09 -0.45548 23.3 EXOC3L4 missense won rs768986918 0.002828745026 95.4089 0.00102358404225 -0.0312625 30.9490969895 rs2282037 399.147 0.00015144255844 EXOC3L4 0.0000 0.0000 0.0110 0.0037 biochemistry_GammaGlutamyltransferase_v2 14:103573121:G:A 14 103573121 A G 0.000263581 0.906993 39.9602 2.6E-10 -0.412194 25.3 EXOC3L4 splice_acceptor won rs2274685 0.0188681544423 3035.1 0.00024841857769 -0.107354 29.736197125 rs11624282 3654.11 0.00010471019584 EXOC3L4 0.2175 0.9497 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 14:103576400:G:A 14 103576400 A G 0.000897939 0.904224 88.3113 5.6E-21 -0.327792 24.7 EXOC3L4 missense won rs150273471 0.0260658404082 105.717 0.021774248721 0.0639716 62.0976328436 rs11624282 3654.11 0.00023612624896 EXOC3L4 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 14:104194141:C:T 14 104194141 T C 0.00032739 0.776838 33.2505 8.1E-09 0.33408 23.4 ZFYVE21 missense lost rs527364203 0.4585865057 51.7032 0.294918508096 -0.250496 3.46490812627 rs11624282 3654.11 0.000564775225 ZFYVE21 0.0268 0.0000 0.0004 0.0000 biochemistry_GammaGlutamyltransferase_v2 16:2120487:G:A 16 2120487 A G 0.00669009 0.874623 33.3641 7.6E-09 -0.0779238 23.7 TSC2 missense lost rs145905454 0.832288138135 68.081 0.407875099801 0.0750252 0.256623077815 16:2153765:G:A 99.202 0.422198453824 TSC2 0.0000 0.0003 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 16:75269046:C:T 16 75269046 T C 0.00150865 0.92918 34.1601 5.1E-09 -0.146495 29.8 BCAR1 missense lost rs193175706 0.81470239737 34.1859 0.814087543824 0.178729 0.324011030128 rs193175706 34.1859 0.814087543824 BCAR1 0.0002 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 17:41063408:C:T 17 41063408 T C 0.000368241 0.927043 30.2866 3.7E-08 0.280847 35 G6PC stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A G6PC 0.0535 0.0000 0.0001 0.0000 biochemistry_GammaGlutamyltransferase_v2 19:10334725:A:G 19 10334725 G A 0.00977547 0.967311 35.1987 3.0E-09 0.0589639 26.0 S1PR2 missense lost rs141801008 1.01047498241 40.4295 0.879738947136 -0.0649332 0.000960522420866 rs8113613 70.8292 0.00209287035441 S1PR2 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 19:49339623:C:A 19 49339623 A C 0.00839199 0.934261 30.9984 2.6E-08 -0.0603454 28.7 HSD17B14 missense lost rs148289102 0.53242175537 37.7761 0.436895882361 0.0668218 2.26527107032 19:49228272:T:C 759.989 0.00437190729616 HSD17B14 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 1:151804213:G:A 1 151804213 A G 0.00341775 0.949492 187.882 9.2E-43 0.238097 36 RORC stop_gained won N/A N/A N/A N/A N/A N/A rs2925739 167.436 0.00037946260804 RORC 0.0001 0.0000 0.0000 0.0145 biochemistry_GammaGlutamyltransferase_v2 20:3672046:C:T 20 3672046 T C 0.00527514 0.964412 97.1968 6.3E-23 0.131256 27.4 SIGLEC1 missense won rs28887921 0.0899680379183 168.263 0.051969864961 -0.0437841 47.633681681 rs28887921 168.263 0.051969864961 SIGLEC1 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 20:3673643:G:A 20 3673643 A G 0.00170402 0.95588 36.7939 1.3E-09 0.136636 24.5 SIGLEC1 missense won 20:3683234_CA_C 0.00202138895323 60.0067 0.00123944131249 0.0154166 33.5597776448 20:3682372:C:T 68.1954 0.000835094404 SIGLEC1 0.0025 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24313774:A:G 22 24313774 G A 8.88803e-05 0.952865 60.1451 8.8E-15 0.811911 25.0 DDT missense lost rs553590368 0.143594553672 89.1061 0.096923878276 -0.510107 23.1989943486 rs2330809 10586.9 0.00010651684849 DDT 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24466964:C:T 22 24466964 T C 0.0059362 0.888949 42.4137 7.4E-11 -0.08191 23.5 CABIN1 missense lost rs56187493 0.995699432827 135.98 0.310569914944 0.107993 0.000196531878818 rs2006227 13250.9 0.00205908120441 CABIN1 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24487714:C:G 22 24487714 G C 0.000566203 0.95989 38.7627 4.8E-10 0.26014 25.3 CABIN1 missense lost rs559743370 0.939828015265 67.4978 0.5397253156 -0.28068 0.0361837835663 rs2006227 13250.9 0.00099780806161 CABIN1 0.0346 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24574054:G:A 22 24574054 A G 0.00467338 0.898898 86.2653 1.6E-20 -0.134255 26.1 CABIN1 missense lost rs117953609 0.99331814129 110.801 0.773358430464 0.164911 0.000966107198817 rs2006227 13250.9 0.001019461041 CABIN1 0.0381 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24709420:C:T 22 24709420 T C 0.00614871 0.946531 164.524 1.2E-37 -0.157477 22.5 SPECC1L missense lost 22:25023492:G:A 0.949872256448 2412.54 0.064776867169 -0.405719 0.106028151763 rs375244580 12234.6 0.00113029767601 SPECC1L 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24919586:G:A 22 24919586 A G 0.00171464 0.950283 198.329 4.8E-45 0.349766 27.6 UPB1 splice_acceptor lost rs138136704 0.957847045835 214.937 0.883835015625 -0.393504 0.0900085648594 rs2006227 13250.9 0.00169028699161 UPB1 0.9571 0.9985 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24981981:G:A 22 24981981 A G 0.000823655 0.900003 33.4405 7.3E-09 0.203249 26.5 FAM211B missense lost rs551112756 0.789689705476 1609.73 0.016404998724 -0.188985 0.414661026732 rs2006227 13250.9 0.00137783500864 LRRC75B 0.0028 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:24982005:C:T 22 24982005 T C 0.00195586 0.867821 114.293 1.1E-26 0.243856 23.7 FAM211B missense lost rs182077968 0.547280962852 130.975 0.477574980624 -0.246537 7.73902555392 rs2006227 13250.9 0.00316018244025 LRRC75B 0.0006 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25010763:G:C 22 25010763 C G 2.26928e-05 0.582743 68.7734 1.1E-16 -2.12145 23.4 GGT1 missense won rs145060794 0.00105063280944 320.098 0.00022572959049 0.541281 64.3872869988 rs145060794 320.098 0.00022572959049 GGT1 0.0003 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25011077:C:G 22 25011077 G C 0.000218433 0.853728 121.925 2.4E-28 -0.756419 24.5 GGT1 missense won rs545359550 0.00968311782704 1243.08 0.000949749124 0.118115 99.1100829614 rs5751902 3400.74 0.00030924629316 GGT1 0.0000 0.0000 0.0000 0.0022 biochemistry_GammaGlutamyltransferase_v2 22:25019109:C:T 22 25019109 T C 7.24555e-05 0.876493 74.3167 6.7E-18 -1.02135 22.5 GGT1 missense won rs530753791 0.00207336973217 127.1 0.00121232097856 0.290534 67.7028726498 rs6004241 721.757 0.00013255837956 GGT1 0.0002 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25019193:G:A 22 25019193 A G 3.60082e-05 0.536641 29.8364 4.7E-08 -1.14193 24.4 GGT1 missense lost rs545359550 0.00631778822379 1243.08 0.00015163952164 0.118115 25.2818364527 rs545359550 1243.08 0.00015163952164 GGT1 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25024147:C:T 22 25024147 T C 0.000117061 0.868446 208.79 2.5E-47 -1.32851 24.8 GGT1 missense won rs545359550 0.0050121672428 1243.08 0.00084185281609 0.118115 180.273220598 rs738818 3771.3 0.00011573886724 GGT1 0.0000 0.0000 0.0063 0.0001 biochemistry_GammaGlutamyltransferase_v2 22:25024150:C:A 22 25024150 A C 3.75539e-05 0.713872 44.9489 2.0E-11 -1.16578 22.4 GGT1 missense won rs143220599 0.00347115835414 65.0876 0.00239715014449 0.0799104 39.808457673 rs5760180 263.118 0.00011857685449 GGT1 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25024287:G:T 22 25024287 T G 3.14786e-05 0.934536 33.2566 8.1E-09 -0.974993 23.8 GGT1 missense lost rs183393092 0.191024254775 169.435 0.037494125956 0.366611 10.5389441333 rs4049732 1214.93 0.000422384704 GGT1 0.0005 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25024733:C:A 22 25024733 A C 0.000645057 0.933457 1305.09 8.9E-286 -1.40846 24.7 GGT1 missense won rs3859862 0.00296911371813 13234.0 0.00029280343225 -0.229933 1166.73736332 rs2006227 13250.9 0.00029212962724 GGT1 0.0011 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25024769:C:T 22 25024769 T C 9.45927e-05 0.810901 139.333 3.7E-32 -1.25142 24.2 GGT1 missense won rs149582824 0.00103463516486 801.146 0.00017994076164 0.069919 130.513659267 rs149582824 801.146 0.00017994076164 GGT1 0.0002 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 22:25155952:TG:T 22 25155952 T TG 0.00149906 0.937675 30.4867 3.4E-08 -0.133508 22.1 PIWIL3 frameshift lost rs755527223 0.71744137958 87.7967 0.249125765625 0.402552 0.713484857722 rs5760497 7581.28 0.00017383895104 N/A N/A N/A N/A N/A biochemistry_GammaGlutamyltransferase_v2 2:27677498:C:A 2 27677498 A C 0.00559263 0.919774 33.4665 7.3E-09 0.0825324 30 IFT172 missense lost 2:27672200:C:T 1.0 33.4665 1.0 0.0825324 0.0 2:27730940:T:C 1360.02 0.00810059401089 IFT172 0.0016 0.0154 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 2:169820801:C:T 2 169820801 T C 0.00277133 0.860571 98.8619 2.7E-23 0.197428 24.3 ABCB11 missense won rs3770586 0.000847179989206 105.366 0.00079488471969 0.0195248 93.1906344103 rs3770586 105.366 0.00079488471969 ABCB11 0.0000 0.0265 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 6:51947999:G:A 6 51947999 A G 0.000662328 0.926468 49.6749 1.8E-12 0.269275 25.5 PKHD1 missense won N/A N/A N/A N/A N/A N/A rs187728966 46.3724 0.842646889764 PKHD1 0.0000 0.0000 0.0015 0.0506 biochemistry_GammaGlutamyltransferase_v2 6:158492660:C:T 6 158492660 T C 0.00541309 0.968157 102.88 3.6E-24 -0.134377 31 SYNJ2 missense won rs6910479 0.00247429312888 155.374 0.00163833895696 -0.0257444 92.8995864139 rs9456946 181.453 0.00091632738681 SYNJ2 0.0004 0.0000 0.0007 0.0000 biochemistry_GammaGlutamyltransferase_v2 6:158508000:C:T 6 158508000 T C 0.00322217 0.945001 114.865 8.4E-27 -0.18413 26.5 SYNJ2 missense won rs9456946 0.00121759530538 181.453 0.00077077306384 -0.0305372 106.988647069 rs9456946 181.453 0.00077077306384 SYNJ2 0.0004 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 6:158508015:C:A 6 158508015 A C 0.00110083 0.917313 30.2845 3.7E-08 -0.156912 26.1 SYNJ2 missense lost rs780160328 1.03360451749 34.0404 0.919560169969 0.16745 0.0084090879058 rs9456946 181.453 0.00032879118276 SYNJ2 0.0000 0.0000 0.0000 0.0000 biochemistry_GammaGlutamyltransferase_v2 8:22885843:C:T 8 22885843 T C 0.000857083 0.84979 46.14 1.1E-11 0.233912 22.6 TNFRSF10B splice_donor won rs190878131 0.00345392702694 313.641 0.00050811020569 -0.0533003 40.8760575021 rs900776 454.931 0.00026742387961 TNFRSF10B 0.0001 0.0000 0.1188 0.9908 biochemistry_GammaGlutamyltransferase_v2 8:67341383:T:G 8 67341383 G T 1.94893e-05 0.74113 31.9712 1.6E-08 -1.3194 26.0 RRS1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A RRS1 0.0000 0.0000 0.0004 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Glucose_v2 16:310007:GGGCCAAC:G 16 310007 G GGGCCAAC 0.00168974 0.950208 31.3055 2.2E-08 -0.153248 27.5 ITFG3 frameshift lost 16:308154_AT_A 0.0105380604806 66.7135 0.00494501491264 0.0213647 25.2080635539 16:308154_AT_A 66.7135 0.00494501491264 N/A N/A N/A N/A N/A biochemistry_Glucose_v2 16:310015:G:A 16 310015 A G 0.00170035 0.947067 31.1451 2.4E-08 -0.152801 23.2 ITFG3 missense lost 16:310007:GGGCCAAC:G 1.00206865262 31.3055 0.996934353156 -0.153248 3.32855716093e-05 16:308154_AT_A 66.7135 0.00490809534084 FAM234A 0.0015 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 16:310018:A:T 16 310018 T A 0.00168974 0.950208 31.3055 2.2E-08 -0.153248 23.2 ITFG3 missense lost 16:310007:GGGCCAAC:G 1.0 31.3055 1.0 -0.153248 0.0 16:308154_AT_A 66.7135 0.00494501491264 FAM234A 0.0000 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 2:169763262:C:T 2 169763262 T C 0.00278884 0.904601 128.453 8.9E-30 -0.240222 27.6 G6PC2 missense won rs12475700 0.0524975642588 1977.93 0.00340935706609 -0.0972348 76.3332755759 rs853773 2079.57 0.00268672208896 G6PC2 0.0000 0.0000 0.0000 0.1462 biochemistry_Glucose_v2 2:169764141:A:C 2 169764141 C A 0.0058324 0.876935 350.069 4.1E-78 -0.277936 24.2 G6PC2 missense won rs56100844 0.466483528327 491.509 0.332245029649 0.206815 35.178972771 2:169763148:T:C 4166.19 0.011609631504 G6PC2 0.0000 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 2:169764368:C:T 2 169764368 T C 0.0031239 0.900881 225.38 6.1E-51 -0.305696 35 G6PC2 stop_gained won rs17539351 0.136998408969 1232.15 0.025059206601 0.127752 89.4155678215 2:169763148:T:C 4166.19 0.00680758656561 G6PC2 0.0000 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 2:169764491:T:C 2 169764491 C T 0.00167447 0.877827 96.0893 1.1E-22 -0.277082 27.7 G6PC2 missense won rs537183 0.109297796391 3663.29 0.00286691710096 -0.136354 43.0569860993 rs853787 3700.08 0.00280201894281 G6PC2 0.0004 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 2:169820801:C:T 2 169820801 T C 0.00277874 0.860571 32.8234 1.0E-08 -0.122894 24.3 ABCB11 missense lost rs188254592 0.595608174115 38.9423 0.502021846225 0.128013 1.70993738565 2:169763148:T:C 4166.19 0.00351216243225 ABCB11 0.0000 0.0265 0.0000 0.0000 biochemistry_Glucose_v2 5:14751305:C:T 5 14751305 T C 0.00706623 0.89517 64.3035 1.1E-15 -0.105168 20.1 ANKH missense won N/A N/A N/A N/A N/A N/A 5:14755919:C:T 56.0012 0.934679036944 ANKH 0.0002 0.0000 0.0000 0.0000 biochemistry_Glucose_v2 7:44184769:A:T 7 44184769 T A 7.35052e-05 0.832446 71.2929 3.1E-17 1.18829 25.9 GCK missense won rs12534623 0.000366992526685 240.654 0.00010872024361 -0.0350309 68.5875408031 rs12534623 240.654 0.00010872024361 GCK 0.0004 0.0000 0.0014 0.0000 biochemistry_Glucose_v2 7:44796125:C:T 7 44796125 T C 9.66996e-05 0.744608 44.552 2.5E-11 0.875093 23.9 ZMIZ2 missense lost 7:44184769:A:T 0.877852496666 71.2929 0.548583160896 1.18829 0.177176056584 7:44184769:A:T 71.2929 0.548583160896 ZMIZ2 0.0000 0.0000 0.0000 0.0010 biochemistry_Glucose_v2 7:100228655:G:T 7 100228655 T G 0.00605792 0.923732 31.1566 2.4E-08 -0.0797331 23.2 TFR2 missense lost 7:100312124_CT_C 0.0770588548533 60.0271 0.039996800064 -0.0279613 16.2596736611 rs111740978 61.6354 0.033674819049 TFR2 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_HbA1c_v2 10:70333117:C:T 10 70333117 T C 0.00126292 0.890423 31.184 2.3E-08 -0.165714 24.3 TET1 missense lost 10:71010275:C:T 0.718882016099 221.232 0.101330805625 -0.246919 0.72171656394 rs17476364 12742.2 0.00122827819024 TET1 0.0002 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 10:71007276:C:T 10 71007276 T C 0.000271612 0.947868 32.9272 9.6E-09 -0.335497 25.6 HKDC1 missense lost rs117118878 0.769093479544 218.57 0.115862628996 0.304152 0.498319660076 rs17476364 12742.2 0.00198453321361 HKDC1 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 10:71020932:A:G 10 71020932 G A 0.00103057 0.918351 83.0923 7.8E-20 -0.268805 25.0 HKDC1 missense lost 10:71078528:G:C 0.849321609501 2236.41 0.0315559696 -0.283365 0.510908189501 rs17476364 12742.2 0.00440650354225 HKDC1 0.0018 0.0145 0.0001 0.0000 biochemistry_HbA1c_v2 11:10483275:A:G 11 10483275 G A 0.000643156 0.897475 41.6291 1.1E-10 0.267356 24.0 AMPD3 missense lost rs187143733 0.356374199685 83.3787 0.177929581489 -0.162509 6.76191849822 11:10508903:G:T 219.521 0.0641203684 AMPD3 0.0000 0.0000 0.0006 0.0012 biochemistry_HbA1c_v2 11:10508808:A:G 11 10508808 G A 0.00245269 0.924909 43.1999 4.9E-11 -0.125273 22.8 AMPD3 missense won rs10840422 0.00661726736838 109.619 0.00260780784889 0.0206511 36.4574363605 11:10512308:C:T 155.854 0.00023163318025 AMPD3 0.0001 0.0016 0.0000 0.0000 biochemistry_HbA1c_v2 11:10508903:G:T 11 10508903 T G 0.00891677 0.937752 219.521 1.2E-49 0.155083 26.6 AMPD3 missense won rs11601212 0.00132565648175 231.327 0.00125800030489 -0.0325395 203.826680849 rs4910498 348.311 0.00076219614241 AMPD3 0.0000 0.0000 0.0002 0.0000 biochemistry_HbA1c_v2 11:10514930:A:G 11 10514930 G A 0.00105326 0.968592 40.3147 2.2E-10 -0.183331 22.1 AMPD3 missense lost rs536592332 0.890774531236 45.0925 0.796392038464 0.185077 0.127292935552 rs4910498 348.311 0.00024036161296 AMPD3 0.0001 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 11:94533444:G:A 11 94533444 A G 0.00708189 0.926701 31.4496 2.0E-08 -0.0652497 25.3 AMOTL1 missense lost rs10639092 0.0066773818041 58.7439 0.00357485605801 -0.0198029 26.5197772412 11:92701596:T:C 445.68 0.00012805638244 AMOTL1 0.0000 0.0000 0.0302 0.0000 biochemistry_HbA1c_v2 12:48534652:C:A 12 48534652 A C 0.00451586 0.953846 31.7211 1.8E-08 0.0828611 22.3 PFKM missense lost 12:48534651:G:A 1.0 31.7211 1.0 0.0828611 0.0 rs2408955 1236.9 0.00412824240196 PFKM 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 12:48535611:G:A 12 48535611 A G 7.45356e-05 0.937683 37.4316 9.5E-10 -0.655432 34 PFKM splice_donor won rs2408955 0.00344379333592 1236.9 0.00010421755569 -0.0655945 33.1672464789 rs2408955 1236.9 0.00010421755569 PFKM 0.0000 0.0000 0.0006 0.9841 biochemistry_HbA1c_v2 12:48539349:A:G 12 48539349 G A 0.000287603 0.780774 35.448 2.6E-09 -0.337857 24.4 PFKM missense lost rs754048009 0.127702384343 42.7065 0.105997778329 0.254476 14.6397750381 rs11395960 406.756 0.00031174846096 PFKM 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 12:109661672:A:G 12 109661672 G A 0.00196812 0.775439 35.9279 2.0E-09 0.152444 24.1 ACACB missense won 12:112072424:A:G 0.00172130751323 180.031 0.00034351286281 -0.0265114 33.0085433173 12:112072424:A:G 180.031 0.00034351286281 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 15:43499436:G:A 15 43499436 A G 0.00630555 0.975953 63.9768 1.3E-15 -0.0980412 24.1 EPB42 missense lost rs191443517 0.884451759251 65.1848 0.868061163204 0.108601 0.226852177971 rs191443517 65.1848 0.868061163204 EPB42 0.0001 0.0000 0.0075 0.0002 biochemistry_HbA1c_v2 16:310007:GGGCCAAC:G 16 310007 G GGGCCAAC 0.00168516 0.950208 36.1177 1.9E-09 -0.138551 27.5 ITFG3 frameshift lost 16:310015:G:A 1.01180789073 36.6473 0.997185982464 -0.139095 0.00125156086599 rs2541602 67.1205 0.00064497713296 N/A N/A N/A N/A N/A biochemistry_HbA1c_v2 16:310015:G:A 16 310015 A G 0.0016953 0.947067 36.6473 1.4E-09 -0.139095 23.2 ITFG3 missense lost 16:205035:G:A 0.0100979317101 53.9496 0.00685940086225 -0.0186018 29.6521000451 rs2541602 67.1205 0.00063515088484 FAM234A 0.0015 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:310018:A:T 16 310018 T A 0.00168516 0.950208 36.1177 1.9E-09 -0.138551 23.2 ITFG3 missense lost 16:310007:GGGCCAAC:G 1.0 36.1177 1.0 -0.138551 0.0 rs2541602 67.1205 0.00064497713296 FAM234A 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:30732558:C:A 16 30732558 A C 0.00903887 0.861269 29.9727 4.4E-08 0.0668718 20.6 SRCAP missense lost rs6565234 0.22578846365 36.6475 0.184664435076 0.0524261 8.25581212684 16:31404571:T:C 217.698 0.00226497942724 SRCAP 0.0119 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:88782159:C:T 16 88782159 T C 0.000219898 0.871875 93.6057 3.9E-22 -0.66553 25.7 PIEZO1 missense won rs180949446 0.00696336490487 121.119 0.00538157222464 0.114729 78.6353223473 rs2926774 181.205 0.00012544672009 PIEZO1 0.0054 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:88782188:T:C 16 88782188 C T 3.52835e-05 0.677431 83.4879 6.4E-20 -1.76271 22.6 PIEZO1 missense won rs192003838 0.000865271810143 98.1961 0.00073566797824 0.359465 78.6484625993 rs192003838 98.1961 0.00073566797824 PIEZO1 0.0161 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:88782205:G:C 16 88782205 C G 0.00145771 0.954236 579.61 4.6E-128 -0.610252 23.3 PIEZO1 missense lost rs562212325 1.02445617406 603.064 0.984613644729 0.60853 0.0856229868237 rs551118 919.301 0.00164578696489 PIEZO1 0.0331 0.0000 0.0001 0.0000 biochemistry_HbA1c_v2 16:88786073:G:A 16 88786073 A G 3.2251e-05 0.839812 248.037 7.0E-56 -2.7775 32 PIEZO1 missense won N/A N/A N/A N/A N/A N/A 16:86602246:C:G 31.2686 0.1070009521 PIEZO1 0.0081 0.0000 0.0002 0.0000 biochemistry_HbA1c_v2 16:88787831:C:G 16 88787831 G C 7.59018e-05 0.938429 86.9483 1.1E-20 -0.993197 25.9 PIEZO1 missense won rs2340980 0.000639064014679 92.8228 0.00059861940889 0.0305193 82.607808959 16:88800545:CGCTTCT:C 112.919 0.00038472468736 PIEZO1 0.0223 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:88793155:C:T 16 88793155 T C 0.00493855 0.958994 48.6617 3.0E-12 0.096246 22.4 PIEZO1 missense lost 16:88853729:T:C 0.0526672597564 848.21 0.00302151400489 -0.0556173 28.8894921351 rs551118 919.301 0.00274427204164 PIEZO1 0.0014 0.0000 0.0046 0.0015 biochemistry_HbA1c_v2 16:88793220:G:A 16 88793220 A G 0.00131412 0.935719 193.923 4.4E-44 -0.378566 24.5 PIEZO1 missense won rs72813548 0.0105455823329 310.808 0.00657972434025 0.0473419 156.139471391 rs551118 919.301 0.00162309877129 PIEZO1 0.0594 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 16:88798288:C:G 16 88798288 G C 0.000188928 0.875973 183.375 8.9E-42 -1.03399 25.8 PIEZO1 missense won N/A N/A N/A N/A N/A N/A rs7404987 128.027 0.00012283953889 PIEZO1 0.0241 0.0000 0.0004 0.0000 biochemistry_HbA1c_v2 16:88798919:G:T 16 88798919 T G 0.00144647 0.936239 567.57 1.9E-125 -0.610459 22.4 PIEZO1 missense lost 16:88782205:G:C 1.010266735 579.61 0.989280879876 -0.610252 0.0148800121865 rs551118 919.301 0.00171187407504 PIEZO1 0.0076 0.0000 0.0001 0.0000 biochemistry_HbA1c_v2 16:88801303:G:A 16 88801303 A G 0.000147051 0.873322 54.1809 1.8E-13 -0.648154 23.1 PIEZO1 missense won 16:88800295:C:T 0.000827202808306 79.9833 0.00056034938089 -0.0220035 51.1091103813 rs71372775 83.9627 0.00014137447801 PIEZO1 0.0137 0.0000 0.0022 0.0136 biochemistry_HbA1c_v2 16:88802726:C:T 16 88802726 T C 0.00036333 0.911279 103.411 2.7E-24 -0.543706 29.6 PIEZO1 missense lost 16:88770218:C:T 1.03622320812 109.421 0.97930816 -0.551289 0.0333211165042 rs860762 305.657 0.00020475320464 PIEZO1 0.0200 0.0000 0.0007 0.0000 biochemistry_HbA1c_v2 17:7496382:C:T 17 7496382 T C 0.00462074 0.825619 45.1873 1.8E-11 0.101563 24.5 FXR2 missense lost rs571192874 0.945481976639 49.5964 0.861429009424 -0.106959 0.0345242834729 rs1641523 249.82 0.00529790369689 FXR2 0.0000 0.0000 0.0002 0.0000 biochemistry_HbA1c_v2 17:16852187:A:G 17 16852187 G A 0.00697525 0.947032 43.1086 5.2E-11 -0.0734359 26.1 TNFRSF13B missense won rs12952818 0.00282014034798 261.911 0.00046417409809 0.0317289 38.6516084458 rs1108646 330.039 0.000207043321 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 17:76115435:G:A 17 76115435 A G 0.00046015 0.923657 33.7722 6.2E-09 0.250644 26.1 TMC6 missense lost 17:76117384_CA_C 0.768300700042 34.9306 0.742821620641 -0.243817 0.514871515065 rs558567978 1589.58 0.00119558967529 TMC6 0.0017 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 17:76134198:G:A 17 76134198 A G 0.00213513 0.895334 45.8535 1.3E-11 0.154631 29.9 TMC8 missense lost rs75163419 0.0726473267825 122.778 0.027131360656 -0.0501042 24.4666923768 rs383603 682.297 0.00055846669761 TMC8 0.0009 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 19:40964064:G:A 19 40964064 A G 0.006774 0.872551 48.5534 3.2E-12 -0.0842615 32 BLVRB missense won rs12983027 0.000276343686706 74.1782 0.00018088098064 0.0230841 46.9525539649 rs2304235 79.0887 0.00015303174436 BLVRB 0.0000 0.0000 0.0546 0.0985 biochemistry_HbA1c_v2 19:41754430:G:A 19 41754430 A G 0.00783434 0.954313 134.021 5.4E-31 -0.129176 31 AXL missense won N/A N/A N/A N/A N/A N/A rs180958600 132.839 0.8960326281 AXL 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 19:55697712:G:A 19 55697712 A G 0.00272576 0.871871 35.7768 2.2E-09 0.106198 41 PTPRH stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A PTPRH 0.0533 0.0577 0.0000 0.0000 biochemistry_HbA1c_v2 1:158450451:G:A 1 158450451 A G 0.00840958 0.967157 34.4502 4.4E-09 0.0568215 23.2 OR10R2 missense lost rs2482963 0.991198452412 1491.4 0.022895926596 -0.0826904 0.000670142883651 rs857720 1504.89 0.022025824921 OR10R2 0.0018 0.0000 0.0015 0.0000 biochemistry_HbA1c_v2 1:158583604:C:A 1 158583604 A C 0.000795834 0.972715 200.931 1.3E-45 -0.476078 27.8 SPTA1 missense won rs1332699 0.00275767944039 555.317 0.00099781437924 -0.0451546 180.381878161 rs857720 1504.89 0.00027930765625 SPTA1 0.0001 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 1:158613207:C:A 1 158613207 A C 0.000412696 0.860242 37.6337 8.5E-10 -0.315403 25.2 SPTA1 missense lost rs186270716 0.125330048216 87.6609 0.0538054416 0.122889 15.7041804131 rs857720 1504.89 0.00017133501025 SPTA1 0.0017 0.0320 0.0000 0.0000 biochemistry_HbA1c_v2 20:43042354:C:T 20 43042354 T C 0.000170908 0.965032 42.723 6.3E-11 0.489863 26.8 HNF4A missense won rs546538128 0.000528620427246 64.3666 0.00035086909225 -0.017061 40.7810314417 rs4812826 70.1446 0.00031831912225 HNF4A 0.0000 0.0050 0.0000 0.0000 biochemistry_HbA1c_v2 21:45742889:G:A 21 45742889 A G 0.000341802 0.944033 61.794 3.8E-15 -0.409578 22.9 PFKL missense won rs9985166 0.000272127494619 62.0012 0.00027121807969 0.0165585 59.7720726918 rs9985166 62.0012 0.00027121807969 PFKL 0.0008 0.0000 0.0822 0.0000 biochemistry_HbA1c_v2 21:45745065:C:A 21 45745065 A C 0.00184012 0.899368 62.7841 2.3E-15 0.187408 28.1 PFKL missense won N/A N/A N/A N/A N/A N/A rs9985166 62.0012 0.00075766966564 PFKL 0.0275 0.0000 0.0027 0.0000 biochemistry_HbA1c_v2 21:45745940:A:G 21 45745940 G A 0.00152026 0.933432 46.8892 7.5E-12 0.152894 22.7 PFKL missense lost 21:45746102:T:C 0.381827852037 137.585 0.130127575824 0.105108 6.84504676445 21:45746102:T:C 137.585 0.130127575824 PFKL 0.0001 0.0000 0.0157 0.0021 biochemistry_HbA1c_v2 21:45746611:C:T 21 45746611 T C 0.00265112 0.899477 82.4541 1.1E-19 0.162149 25.2 PFKL missense won rs2236670 0.000474846176604 85.0598 0.00046029986116 0.0256529 78.8997441204 rs2236670 85.0598 0.00046029986116 PFKL 0.0001 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 22:36682799:T:C 22 36682799 C T 0.000703157 0.903378 46.684 8.3E-12 -0.263835 25.4 MYH9 missense won 22:37470604:G:A 0.00334130759257 1161.91 0.00013424929956 -0.0656279 41.4429375509 22:37462936:A:G 1272.31 0.00010251765001 MYH9 0.0000 0.0000 0.0005 0.0007 biochemistry_HbA1c_v2 2:24245713:C:G 2 24245713 G C 0.00484429 0.972585 57.8688 2.8E-14 0.109142 26.0 MFSD2B missense lost rs150221884 0.916553131544 61.2226 0.866343962176 -0.119361 0.105176733318 2:24239189:T:TCCTGGC 355.646 0.029920696576 MFSD2B 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 2:39241107:G:A 2 39241107 A G 0.00971495 0.95699 37.7379 8.1E-10 -0.0608621 23.0 SOS1 missense won rs13383778 0.000148170258529 42.4556 0.00013170546169 0.0139213 36.8247609017 rs62132519 42.5591 0.00012912458689 SOS1 0.0005 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 2:68615546:A:C 2 68615546 C A 0.00873164 0.982982 41.584 1.1E-10 -0.0645876 21.6 PLEK missense won N/A N/A N/A N/A N/A N/A rs141250842 31.7618 0.785440835001 PLEK 0.0013 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 2:169763262:C:T 2 169763262 T C 0.00279588 0.904601 87.7309 7.5E-21 -0.175675 27.6 G6PC2 missense won rs12475700 0.0636143748192 1593.71 0.00350185815225 -0.076949 49.0570637149 rs853773 1640.6 0.00273994668025 G6PC2 0.0000 0.0000 0.0000 0.1462 biochemistry_HbA1c_v2 2:169764141:A:C 2 169764141 C A 0.00581723 0.876935 249.532 3.3E-56 -0.208261 24.2 G6PC2 missense won rs56100844 0.392439865213 294.686 0.332307284521 0.144607 34.8195570006 2:169763148:T:C 2895.03 0.011425258321 G6PC2 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 2:169764368:C:T 2 169764368 T C 0.00311619 0.900881 131.126 2.3E-30 -0.207714 35 G6PC2 stop_gained won rs17539351 0.158147932551 839.592 0.0246992656 0.0918256 47.5714084998 2:169763148:T:C 2895.03 0.00668657821225 G6PC2 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 2:169764491:T:C 2 169764491 C T 0.00166055 0.877827 46.2036 1.1E-11 -0.170526 27.7 G6PC2 missense lost rs537183 0.159933254208 2612.35 0.00282867613609 -0.100695 16.637922648 rs537183 2612.35 0.00282867613609 G6PC2 0.0004 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 3:47467597:C:T 3 47467597 T C 0.0049387 0.925606 52.7177 3.9E-13 0.105213 22.8 SCAP missense lost rs147345916 0.815963714652 58.4992 0.735321685081 -0.118178 0.492885040374 3:49643173_AATAT_A 317.791 0.00368977279225 SCAP 0.0025 0.0000 0.0001 0.0000 biochemistry_HbA1c_v2 3:48506279:G:A 3 48506279 A G 0.00793262 0.93462 57.7076 3.0E-14 0.0810993 24.1 ATRIP missense lost 3:49210836_ACTC_A 0.741008870406 85.4644 0.500346851904 -0.138403 1.11787864309 3:49643173_AATAT_A 317.791 0.00379545941329 ATRIP 0.0033 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 3:49044932:G:T 3 49044932 T G 0.0063664 0.652554 33.1483 8.5E-09 -0.0796912 27.3 WDR6 missense lost rs62263025 0.479785271256 38.6615 0.411367021641 0.0505246 3.13100922215 3:49362369:C:T 325.534 0.00079946997001 WDR6 0.0000 0.0000 0.1055 0.0000 biochemistry_HbA1c_v2 3:171417570:G:A 3 171417570 A G 0.00459823 0.934652 46.15 1.1E-11 0.0946047 26.9 PLD1 missense won rs1563436 0.00223770697963 272.955 0.000378341401 -0.0318337 41.8870733544 rs13073970 295.924 0.00017650716736 PLD1 0.0000 0.0000 0.0003 0.2757 biochemistry_HbA1c_v2 3:171442535:C:A 3 171442535 A C 0.00282339 0.909048 53.96 2.0E-13 0.140745 25.9 PLD1 missense won rs144931719 0.00775732793126 75.0147 0.00558004518009 -0.0275312 44.8734564834 rs1604038 548.047 0.00031935834436 PLD1 0.0443 0.0000 0.0223 0.0000 biochemistry_HbA1c_v2 4:89013496:C:T 4 89013496 T C 0.00483892 0.971028 37.6035 8.7E-10 0.0764504 21.5 ABCG2 missense lost rs2725252 0.0128427546457 82.0966 0.00588249116676 0.0168724 29.5635332105 rs2622622 102.222 0.00227818153809 ABCG2 0.0001 0.0206 0.0007 0.0000 biochemistry_HbA1c_v2 4:110638824:C:T 4 110638824 T C 0.0076835 0.943901 40.7581 1.7E-10 -0.0722273 26.2 PLA2G12A missense lost rs189866430 0.989100292046 44.9237 0.897384868416 0.0858617 0.00121719521709 4:110914427:A:T 56.2423 0.00126260119561 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 5:14751305:C:T 5 14751305 T C 0.00711465 0.89517 224.917 7.7E-51 -0.172131 20.1 ANKH missense won N/A N/A N/A N/A N/A N/A 5:14755919:C:T 203.162 0.937587460681 ANKH 0.0002 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 6:49586904:A:G 6 49586904 G A 6.45557e-05 0.668236 31.474 2.0E-08 -0.772463 24.7 RHAG missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A RHAG 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 6:49604368:C:T 6 49604368 T C 0.000230303 0.858624 162.606 3.0E-37 -0.840751 34 RHAG splice_donor won N/A N/A N/A N/A N/A N/A rs544677242 37.3495 0.153637345156 RHAG 0.0004 0.0000 0.3148 0.9729 biochemistry_HbA1c_v2 7:44184769:A:T 7 44184769 T A 7.58436e-05 0.832446 103.01 3.3E-24 1.1952 25.9 GCK missense won rs12534623 0.000616853647167 537.441 0.00011823082756 -0.0461588 97.956718422 rs12534623 537.441 0.00011823082756 GCK 0.0004 0.0000 0.0014 0.0000 biochemistry_HbA1c_v2 7:44192905:C:T 7 44192905 T C 6.41033e-05 0.851357 32.0318 1.5E-08 0.764406 28.6 GCK missense won rs307009 0.0012508310569 54.9534 0.00072909720324 0.0329764 29.8061232617 7:44163862_CT_C 82.1374 0.00013010596096 GCK 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 7:44796125:C:T 7 44796125 T C 9.95257e-05 0.744608 58.238 2.3E-14 0.849116 23.9 ZMIZ2 missense lost 7:44184769:A:T 1.00945168176 103.01 0.570706213401 1.1952 0.00129455191561 7:44184769:A:T 103.01 0.570706213401 ZMIZ2 0.0000 0.0000 0.0000 0.0010 biochemistry_HbA1c_v2 7:100225847:C:T 7 100225847 T C 0.00514655 0.994125 56.0109 7.2E-14 -0.0990085 21.6 NONE N/A won rs12534494 0.00139227137297 75.2817 0.001035874225 -0.0177017 51.9089958307 rs117370443 136.928 0.00010823905444 TFR2 0.0014 0.0000 0.5241 0.4540 biochemistry_HbA1c_v2 7:100228655:G:T 7 100228655 T G 0.00603112 0.923732 54.5296 1.5E-13 -0.0972509 23.2 TFR2 missense won rs35474292 0.00287831743688 68.1949 0.00230154305536 -0.0182985 48.8355325646 7:99052428:T:C 117.85 0.00012990072676 TFR2 0.0000 0.0000 0.0000 0.0000 biochemistry_HbA1c_v2 8:41575677:G:A 8 41575677 A G 0.00137433 0.91167 122.299 2.0E-28 -0.295574 29.2 ANK1 missense won rs569451 0.00257765876806 864.316 0.000364733604 -0.0622102 110.195845962 rs4737010 1466.4 0.00018686616601 ANK1 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_HDLcholesterol_v2 10:71883836:C:A 10 71883836 A C 0.0074856 0.887584 47.3023 6.1E-12 -0.0773283 25.1 AIFM2 missense won N/A N/A N/A N/A N/A N/A rs547427642 35.9426 0.658782215716 AIFM2 0.0000 0.0000 0.0008 0.0000 biochemistry_HDLcholesterol_v2 11:14865399:C:T 11 14865399 T C 0.00106686 0.906863 247.309 1.0E-55 0.468027 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs558528882 119.73 0.439071890625 PDE3B 0.1111 0.0139 0.0003 0.0000 biochemistry_HDLcholesterol_v2 11:14865514:A:G 11 14865514 G A 0.000168205 0.881821 35.1395 3.1E-09 0.505662 26.3 PDE3B missense won rs7949801 0.000655575684244 42.4876 0.00054219588201 -0.0133108 33.36309817 rs577940046 43.9967 0.00012506619889 PDE3B 0.0001 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:14891141:G:C 11 14891141 C G 0.00658732 0.980636 46.7207 8.2E-12 0.077463 22.6 PDE3B missense lost rs188198602 1.02252240281 52.0241 0.918285225984 -0.0870912 0.00585907304059 11:14616038:C:T 97.3699 0.00349241995089 PDE3B 0.0001 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 11:47282095:G:A 11 47282095 A G 6.2946e-05 0.770264 29.8686 4.6E-08 0.736485 33 NR1H3 missense lost rs149873792 0.0187184099844 43.6221 0.012816730521 -0.777608 22.2547333263 11:47350287:G:A 431.307 0.00019960886089 NR1H3 0.1360 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:47290147:G:A 11 47290147 A G 0.000661268 0.910265 180.572 3.6E-41 0.522805 33 NR1H3 missense won rs1566729 0.00237358521174 243.474 0.00176036467489 0.041788 163.405864483 rs35184771 387.978 0.00033471434304 NR1H3 0.0012 0.0004 0.0029 0.0000 biochemistry_HDLcholesterol_v2 11:116655859:C:T 11 116655859 T C 0.00544129 0.938996 48.9086 2.7E-12 0.0907105 24.4 ZNF259 missense lost 11:116903390_CT_C 0.182402838051 538.483 0.016567036369 -0.0647682 16.0532664874 11:116648917:C:G 2213.82 0.00086029582864 ZPR1 0.0004 0.0000 0.0002 0.0000 biochemistry_HDLcholesterol_v2 11:116661001:G:A 11 116661001 A G 0.000400315 0.941055 65.2994 6.4E-16 -0.380879 24.4 APOA5 missense won 11:116638691_AAAT_A 0.00571450454445 665.593 0.00056063347729 -0.0504062 55.8000233643 11:116638691_AAAT_A 665.593 0.00056063347729 APOA5 0.0002 0.0000 0.0007 0.0000 biochemistry_HDLcholesterol_v2 11:116661122:G:A 11 116661122 A G 0.00010361 0.98376 47.3095 6.1E-12 -0.648948 35 APOA5 stop_gained won 11:116663707:A:G 0.0382820552776 1090.62 0.00166061955049 -0.130171 30.6076400327 11:116648917:C:G 2213.82 0.00066572256256 APOA5 0.0020 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 11:116661392:C:A 11 116661392 A C 0.000163816 0.926507 31.2284 2.3E-08 -0.433439 22.7 APOA5 missense lost 11:116663707:A:G 0.0807306017295 1090.62 0.00231160947264 -0.130171 16.0035550759 11:116663707:A:G 1090.62 0.00231160947264 APOA5 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:116661656:G:A 11 116661656 A G 0.000262152 0.934111 112.158 3.3E-26 -0.641584 37 APOA5 stop_gained won rs180327 0.00163949726758 412.966 0.00044527330225 -0.0398941 103.259169541 rs180327 412.966 0.00044527330225 APOA5 0.0000 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 11:116662297:C:G 11 116662297 G C 0.000148375 0.802277 74.7352 5.4E-18 -0.75142 22.1 NONE N/A won 11:116660686:A:G 0.0231701987742 1229.59 0.00140829824529 -0.129949 53.7148033774 11:116648917:C:G 2213.82 0.00063314637376 APOA5 0.0004 0.0001 0.0134 0.9766 biochemistry_HDLcholesterol_v2 11:116701353:C:T 11 116701353 T C 0.00018648 0.815693 171.92 2.8E-39 0.975158 35 APOC3 stop_gained won rs2849174 0.000929166801906 357.199 0.00044720829729 -0.0404389 161.598729821 rs1729410 576.987 0.00017820114064 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:116701354:G:A 11 116701354 A G 0.00223176 0.92045 2293.71 1.4E-500 0.992167 31 APOC3 splice_donor won N/A N/A N/A N/A N/A N/A 11:116648917:C:G 2213.82 0.00025025974416 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_HDLcholesterol_v2 11:116701549:C:A 11 116701549 A C 1.95664e-05 0.923653 33.4497 7.3E-09 1.34822 22.9 APOC3 missense lost 11:116655859:C:T 0.00526363021796 48.9086 0.00359991600049 0.0907105 28.7721564968 11:116903390_CT_C 538.483 0.00011709620521 APOC3 0.0039 0.0000 0.0050 0.0000 biochemistry_HDLcholesterol_v2 11:116701560:G:A 11 116701560 A G 0.00038277 0.859578 152.604 4.7E-35 0.657943 23.2 APOC3 missense won rs7118999 0.000697033679432 933.907 0.00011389798729 -0.0659716 144.652453038 rs7118999 933.907 0.00011389798729 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:116706934:ACTT:A 11 116706934 A ACTT 0.000263962 0.80538 77.9061 1.1E-18 -0.563235 20.4 APOA1 inframe_deletion won rs7946423 0.000269252339731 178.287 0.00011765523961 0.0303102 75.3703679744 rs7946423 178.287 0.00011765523961 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 11:116707044:A:T 11 116707044 T A 0.000843393 0.946132 221.634 4.0E-50 -0.485094 25.2 APOA1 missense won 11:116660686:A:G 0.0571619934775 1229.59 0.010303468036 -0.129949 128.323981234 11:116648917:C:G 2213.82 0.00485942833216 APOA1 0.0005 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 11:116707739:A:C 11 116707739 C A 0.00100513 0.885482 224.967 7.5E-51 -0.485337 22.8 APOA1 missense won rs1729410 0.00157558769393 576.987 0.00061432101025 -0.0463705 207.461922069 rs1729410 576.987 0.00061432101025 APOA1 0.0001 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 12:108686555:A:C 12 108686555 C A 0.00626925 0.940479 30.3163 3.7E-08 -0.0669833 26.0 CMKLR1 missense lost rs574092892 0.976986781773 34.1282 0.867863654464 0.0757808 0.00406080241805 rs7300422 74.137 0.00061207254801 CMKLR1 0.0000 0.0000 0.0015 0.0000 biochemistry_HDLcholesterol_v2 12:109661672:A:G 12 109661672 G A 0.00197101 0.775439 42.9352 5.7E-11 0.158001 24.1 ACACB missense won rs369843838 0.00641779342065 98.5144 0.00279704534641 -0.0288043 36.3315743214 rs11065991 309.311 0.000341251729 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 12:111885310:G:A 12 111885310 A G 0.00199515 0.885884 137.269 1.1E-31 -0.250086 32 SH2B3 missense lost rs570074821 0.97675299382 141.631 0.9466706209 0.246429 0.0187645929473 rs7296044 342.233 0.00015039833769 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_HDLcholesterol_v2 12:123875330:G:A 12 123875330 A G 0.00422725 0.942379 32.7516 1.0E-08 -0.0838661 24.6 SETD8 missense lost rs7312706 0.491266688128 106.974 0.150408230625 0.0638599 2.92990251102 12:124409502:G:A 572.034 0.00043714028241 SETD8 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 12:125284671:G:A 12 125284671 A G 0.000244606 0.922287 84.0201 4.9E-20 0.564158 31 SCARB1 missense won rs79454364 0.00357890461458 135.699 0.00221593323169 -0.0619073 74.2679719331 12:124409502:G:A 572.034 0.00023986265625 SCARB1 0.0000 0.0000 0.0008 0.0004 biochemistry_HDLcholesterol_v2 12:125292360:C:A 12 125292360 A C 0.000570776 0.940269 261.465 8.2E-59 0.667021 27.4 SCARB1 missense won rs921919 0.00237342972749 596.162 0.00104093988496 0.0507165 236.609539108 rs921919 596.162 0.00104093988496 SCARB1 0.0000 0.0000 0.0002 0.0000 biochemistry_HDLcholesterol_v2 12:125294817:C:A 12 125294817 A C 0.000365278 0.939731 52.4748 4.4E-13 0.369865 24.2 SCARB1 missense won rs80194043 0.013720437729 70.5274 0.010208475369 -0.0435061 40.9015822098 rs921919 596.162 0.00067913402404 SCARB1 0.3376 0.0693 0.0000 0.0000 biochemistry_HDLcholesterol_v2 12:125296427:C:T 12 125296427 T C 0.000220886 0.821747 67.8859 1.7E-16 0.581225 28.9 SCARB1 missense won rs117314711 0.00499247457681 75.8009 0.00447116894224 -0.0480912 58.6315300976 rs921919 596.162 0.00023037471961 SCARB1 0.0003 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 12:125298855:T:C 12 125298855 C T 0.000287061 0.940952 143.949 3.6E-33 0.666285 23.8 SCARB1 missense won rs764391747 0.0020931894397 145.928 0.00206480268801 -0.0366811 131.078579626 rs921919 596.162 0.00045656578276 SCARB1 0.0002 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 12:125299614:C:T 12 125299614 T C 0.000604942 0.818572 121.898 2.4E-28 0.450914 25.4 SCARB1 missense won 12:125288235_CAAAAAAAAAAAAA_C 0.00234408304761 394.563 0.00072419115664 0.0401043 110.380177381 12:125288235_CAAAAAAAAAAAAA_C 394.563 0.00072419115664 SCARB1 0.0025 0.0006 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:58838103:A:ACG 15 58838103 ACG A 0.000509239 0.929914 126.473 2.4E-29 0.512297 35 LIPC frameshift won 15:58720262:T:C 0.000551856346227 138.198 0.000505035729 0.103242 120.600682883 rs35717353 462.314 0.00014218416081 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 15:58840586:C:T 15 58840586 T C 0.00144024 0.933085 220.936 5.7E-50 0.386403 23.9 LIPC missense won rs473224 0.0265196054155 2272.45 0.00257833419529 0.129673 154.836981866 rs2070895 3956.33 0.00144355163481 LIPC 0.0033 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:58855748:C:T 15 58855748 T C 0.00199461 0.925982 242.434 1.2E-54 0.337195 24.2 LIPC missense won rs2043084 0.00494605179842 2396.27 0.00050039900416 -0.110446 209.533210946 rs261290 4020.27 0.00024455642689 LIPC 0.0024 0.0569 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:58855765:G:C 15 58855765 C G 0.000468208 0.890932 36.0555 1.9E-09 0.28021 25.0 LIPC missense lost rs8033940 0.0101367643879 2588.15 0.00014121519556 -0.10673 29.1607424813 rs8033940 2588.15 0.00014121519556 LIPC 0.0051 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:90210353:CTTCTGCAGGGT:C 15 90210353 C CTTCTGCAGGGT 0.000305629 0.910204 80.7242 2.6E-19 0.523351 28.7 PLIN1 frameshift won N/A N/A N/A N/A N/A N/A 15:90210367:G:C 80.7242 1.0 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 15:90210367:G:C 15 90210367 C G 0.000305629 0.910204 80.7242 2.6E-19 0.523351 21.3 PLIN1 missense lost 15:90210353:CTTCTGCAGGGT:C 1.0 80.7242 1.0 0.523351 0.0 15:90210353:CTTCTGCAGGGT:C 80.7242 1.0 PLIN1 0.0243 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:90214769:G:A 15 90214769 A G 0.000148463 0.801041 32.4494 1.2E-08 0.476591 36 PLIN1 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A PLIN1 0.0122 0.0031 0.0000 0.0000 biochemistry_HDLcholesterol_v2 15:90214777:A:G 15 90214777 G A 0.00118746 0.93376 82.2622 1.2E-19 0.256123 30 PLIN1 missense won N/A N/A N/A N/A N/A N/A rs565712230 47.8783 0.547906402849 PLIN1 0.0192 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:56459029:G:A 16 56459029 A G 0.000218513 0.826852 32.8204 1.0E-08 0.402626 22.8 AMFR missense lost 16:57007295:C:T 0.346009376937 43.1432 0.2632203025 0.541062 5.56496604979 rs183130 18150.0 0.00026595412561 AMFR 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:56667294:G:A 16 56667294 A G 0.00256778 0.919112 41.555 1.1E-10 0.128558 23.4 MT1M missense lost rs56156922 0.810318326203 17810.0 0.00189066693124 -0.265241 0.41408166094 rs183130 18150.0 0.001840581604 MT1M 0.0000 0.0000 0.0013 0.0005 biochemistry_HDLcholesterol_v2 16:56686510:G:C 16 56686510 C G 0.0058177 0.990628 35.8444 2.1E-09 0.0688411 22.5 MT1B missense lost rs75056259 1.00183766652 35.9647 0.998486573049 -0.0688577 3.02340244192e-05 rs183130 18150.0 0.00150150825049 MT1B 0.0001 0.0076 0.0001 0.0000 biochemistry_HDLcholesterol_v2 16:56867169:T:G 16 56867169 G T 1.91113e-05 0.907108 33.2543 8.1E-09 1.32677 31 NUP93 missense lost rs9923854 0.00445297101323 964.306 0.000153561664 -0.0980604 28.9642226291 rs9923854 964.306 0.000153561664 NUP93 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:56936421:G:T 16 56936421 T G 0.000796608 0.901784 42.096 8.7E-11 0.224023 32 SLC12A3 splice_donor lost rs146957515 1.09422308778 146.347 0.314747928576 -0.249869 0.0892734885779 16:56997233:G:A 13197.5 0.00015011885529 SLC12A3 0.0002 0.0000 0.1172 0.9928 biochemistry_HDLcholesterol_v2 16:57003374:C:T 16 57003374 T C 2.39112e-05 0.768026 31.639 1.9E-08 1.24299 35 CETP stop_gained lost 16:56867169:T:G 0.980982216605 33.2543 0.933331820281 1.32677 0.0028882978443 rs9923854 964.306 0.00016275380625 CETP 0.0028 0.0000 0.0002 0.0000 biochemistry_HDLcholesterol_v2 16:57003551:G:A 16 57003551 A G 0.000260327 0.941636 182.021 1.8E-41 0.799979 22.8 CETP missense won 16:57007353:C:T 0.0307633431173 1261.92 0.00443734505956 0.149981 123.769493172 rs12923459 9453.98 0.00019163418624 CETP 0.0341 0.0063 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:57004961:C:T 16 57004961 T C 3.38289e-05 0.750476 37.2918 1.0E-09 1.11469 36 CETP stop_gained won 16:57002641_CT_C 0.0069643829055 999.734 0.00025978347684 -0.11879 31.3272982765 rs76976871 1083.46 0.00010793755449 CETP 0.0098 0.2695 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:57007361:T:C 16 57007361 C T 0.000236308 0.917645 189.421 4.3E-43 0.827392 23.9 CETP missense won rs564283356 0.0612481689848 371.568 0.031223596804 -0.250496 107.265479324 rs183130 18150.0 0.000444450724 CETP 0.0004 0.0000 0.0068 0.0000 biochemistry_HDLcholesterol_v2 16:57009034:TTCAACACCAA:T 16 57009034 T TTCAACACCAA 9.42062e-05 0.863326 100.23 1.4E-23 1.01839 32 CETP frameshift won rs12720917 0.00306535139994 1019.28 0.00030142862689 -0.0868513 89.438648851 rs12720917 1019.28 0.00030142862689 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 16:57012174:C:T 16 57012174 T C 0.00152391 0.933901 48.5165 3.3E-12 -0.167865 LOW NONE N/A lost 16:56997233:G:A 1.00895651369 13197.5 0.00370911450625 -0.242338 0.000968654894456 rs183130 18150.0 0.00055039036816 CETP 0.0000 0.0000 0.8180 0.0032 biochemistry_HDLcholesterol_v2 16:57016126:T:G 16 57016126 G T 3.90642e-05 0.628434 48.5054 3.3E-12 1.33605 24.0 CETP missense won rs768356707 0.00850094757409 2634.56 0.00015651261025 0.143324 39.9732895091 rs289742 2642.54 0.000154703844 CETP 0.0002 0.0000 0.0038 0.0136 biochemistry_HDLcholesterol_v2 16:57416892:G:A 16 57416892 A G 0.000374956 0.816754 33.2041 8.3E-09 -0.276084 25.6 CX3CL1 missense lost 16:56916652_TGTGACCAGCCTGGCCAACATG_T 1.07202858663 608.926 0.058456601284 0.548356 0.04158215786 16:57005301:C:T 14796.5 0.00011186023696 CX3CL1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:66956088:C:T 16 66956088 T C 1.88178e-05 0.843144 51.0578 9.0E-13 -1.70273 32 RRAD missense lost 16:67976870:G:T 0.90938242968 116.083 0.399981618481 -1.47718 0.109852200693 16:67976870:G:T 116.083 0.399981618481 RRAD 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:67166731:G:A 16 67166731 A G 0.0067988 0.967352 48.9875 2.6E-12 0.0796793 22.8 C16orf70 missense lost rs77960079 0.986746825708 51.9047 0.931288691089 -0.0805588 0.0021654960873 rs55781197 634.425 0.040996935529 C16orf70 0.0001 0.0480 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:67304881:G:A 16 67304881 A G 2.87991e-05 0.686311 100.278 1.3E-23 -2.12358 LOW SLC9A5 missense won rs78539049 0.000887211497145 241.882 0.00036781486225 0.0679924 94.393187585 rs78539049 241.882 0.00036781486225 SLC9A5 0.7844 0.0000 0.0012 0.0000 biochemistry_HDLcholesterol_v2 16:67976870:G:T 16 67976870 T G 5.08118e-05 0.881171 116.083 4.6E-27 -1.47718 36 LCAT stop_gained won N/A N/A N/A N/A N/A N/A rs377115620 85.4214 0.00046753683076 LCAT 0.1157 0.0040 0.0000 0.0000 biochemistry_HDLcholesterol_v2 16:69149158:G:A 16 69149158 A G 6.70609e-05 0.928914 45.5367 1.5E-11 0.774587 23.7 HAS3 missense lost 16:66609070:G:A 0.888050901662 66.2451 0.610443753481 0.795367 0.151265984582 rs8182201 447.406 0.00013779942544 HAS3 0.0000 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 17:40948319:C:T 17 40948319 T C 0.00357816 0.930029 48.5268 3.3E-12 -0.109513 28.4 WNK4 missense lost rs145947882 0.977032641622 1265.78 0.037456957444 0.214558 0.00647402788776 17:41926126:C:T 1584.3 0.028780443904 WNK4 0.0000 0.0000 0.0003 0.0040 biochemistry_HDLcholesterol_v2 17:40970264:C:T 17 40970264 T C 0.00303165 0.931723 54.0128 2.0E-13 -0.121536 23.0 BECN1 missense lost 17:41926126:C:T 1.02947468496 1584.3 0.035097399649 -0.219198 0.0115612369969 17:41926126:C:T 1584.3 0.035097399649 BECN1 0.0000 0.0000 0.0046 0.0002 biochemistry_HDLcholesterol_v2 18:47101922:G:A 18 47101922 A G 5.97363e-05 0.887131 32.2821 1.3E-08 0.656231 29.0 LIPG missense lost rs57256704 0.0092267917649 349.674 0.000851822596 -0.0716123 26.3781691092 rs7229377 648.955 0.00011496342841 LIPG 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 18:47113165:C:T 18 47113165 T C 0.00266962 0.908785 654.489 2.4E-144 0.487363 29.8 LIPG missense won rs34802337 0.00466450572942 665.143 0.004589791504 -0.0517774 568.142352663 18:47167214:C:T 1835.35 0.00054454089316 LIPG 0.0000 0.0022 0.0000 0.0000 biochemistry_HDLcholesterol_v2 18:48331611:CAG:C 18 48331611 C CAG 0.00912553 0.947787 33.852 5.9E-09 0.0574413 34 MRO frameshift lost rs549483920 0.345809154486 42.4781 0.275585101444 -0.0977213 5.74462863753 18:47167214:C:T 1835.35 0.00014120806561 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 19:3382176:C:T 19 3382176 T C 0.00164285 0.909897 46.813 7.8E-12 -0.171984 26.0 NFIC missense won rs12975319 0.00471211631491 65.5895 0.00336316485184 0.0170864 40.6066449725 rs12975319 65.5895 0.00336316485184 NFIC 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 19:11350874:C:T 19 11350874 T C 0.00046626 0.861956 94.4294 2.5E-22 0.437841 36 C19orf80 stop_gained won rs116846441 0.0282140980066 505.161 0.00527404203076 -0.335459 65.3709281447 19:8429323:G:A 1253.23 0.00095081572609 DOCK6 0.0004 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 19:45404058:C:T 19 45404058 T C 0.00181043 0.927388 32.2466 1.4E-08 -0.12866 25.2 TOMM40 missense lost 19:45410002:G:A 0.519091739159 1352.69 0.012374560081 -0.107267 2.51946912081 19:45411941:T:C 1635.07 0.00943460599761 TOMM40 0.0000 0.0000 0.0003 0.0000 biochemistry_HDLcholesterol_v2 19:45667499:A:T 19 45667499 T A 0.00335927 0.913101 35.4465 2.6E-09 -0.104247 25.3 TRAPPC6A missense lost 19:45369564_AG_A 0.230976050801 169.079 0.048422882704 0.158461 9.56263958961 19:45411941:T:C 1635.07 0.00154254133504 TRAPPC6A 0.0067 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 1:63063465:C:G 1 63063465 G C 0.00218525 0.867438 47.2223 6.3E-12 0.14482 23.0 ANGPTL3 missense won 1:63191777:C:T 0.00091394112621 79.9856 0.00053957714944 -0.0204385 44.4102603292 1:63191777:C:T 79.9856 0.00053957714944 DOCK7 0.0003 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 1:63063592:GAACTC:G 1 63063592 G GAACTC 0.000626559 0.889289 66.4363 3.6E-16 -0.321092 34 ANGPTL3 frameshift won N/A N/A N/A N/A N/A N/A rs566523636 31.8325 0.248688723969 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 1:63063667:CAACT:C 1 63063667 C CAACT 0.000236841 0.856004 40.1886 2.3E-10 -0.413188 33 ANGPTL3 frameshift won rs12079483 0.000302508274357 41.4736 0.00029313548944 0.0161123 38.802775633 rs12079483 41.4736 0.00029313548944 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 1:63069706:T:G 1 63069706 G T 0.000415145 0.870862 67.5453 2.1E-16 -0.442095 26.5 ANGPTL3 missense won N/A N/A N/A N/A N/A N/A rs374131620 44.445 0.00012741217129 DOCK7 0.0064 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 1:220101499:G:A 1 220101499 A G 0.00117558 0.883767 59.2899 1.4E-14 -0.224402 28.7 SLC30A10 missense won rs12034581 0.001046112867 112.785 0.00054993064036 0.0194832 55.5166182312 1:220970028:A:G 298.354 0.00011640899449 SLC30A10 0.0009 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 20:43042354:C:T 20 43042354 T C 0.000174517 0.965032 56.5764 5.4E-14 -0.533776 26.8 HNF4A missense won rs181884454 0.0118777692136 195.143 0.00344363580625 0.0715021 44.9164232743 20:44554015:T:C 1200.03 0.00012493427076 HNF4A 0.0000 0.0050 0.0000 0.0000 biochemistry_HDLcholesterol_v2 20:44519224:C:CT 20 44519224 CT C 0.0082039 0.955902 72.468 1.7E-17 -0.090184 33 NEURL2 frameshift lost rs149487415 0.540449992941 338.934 0.115554444489 0.0787714 5.08318901206 20:44554015:T:C 1200.03 0.030402804496 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 20:44538243:G:A 20 44538243 A G 0.000648513 0.942839 56.5565 5.5E-14 -0.288743 24.3 PLTP missense won rs13038523 0.00619529919805 59.7227 0.00586685530116 0.0287566 48.0037349897 20:44538484:G:T 325.353 0.0001879641 PLTP 0.0099 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 2:21238367:C:T 2 21238367 T C 0.00517084 0.966793 35.3951 2.7E-09 0.0810108 21.1 APOB missense lost rs142565602 0.8863571242 35.7139 0.878445060516 -0.0869177 0.121274155211 rs2678379 1040.12 0.019481738929 APOB 0.0691 0.0437 0.0000 0.0000 biochemistry_HDLcholesterol_v2 2:219878668:T:C 2 219878668 C T 0.004476 0.931881 50.0781 1.5E-12 -0.11513 25.7 CCDC108 missense lost rs115145659 0.883068324539 59.588 0.742135729729 0.114714 0.181984909182 rs78058190 386.136 0.089547570025 CCDC108 0.0000 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 3:70014091:G:A 3 70014091 A G 0.0040862 0.961313 32.0675 1.5E-08 0.0848735 31 MITF missense lost rs7630455 0.00629917141255 33.7584 0.00598365678681 -0.0117519 27.1792756399 rs17006441 39.3103 0.00198804515625 MITF 0.0001 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 4:100515943:A:C 4 100515943 C A 6.36995e-05 0.724397 30.9382 2.7E-08 -0.748812 22.2 MTTP missense lost 4:103283117:A:G 0.000812716484811 249.202 0.00010089800704 -0.0578188 29.1993602648 4:103283117:A:G 249.202 0.00010089800704 MTTP 0.0226 0.0000 0.0073 0.0000 biochemistry_HDLcholesterol_v2 4:110638764:A:G 4 110638764 G A 0.00170327 0.93174 72.2925 1.9E-17 -0.181313 25.5 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs113824614 29.9917 0.345929832964 PLA2G12A 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 4:110638824:C:T 4 110638824 T C 0.00773297 0.943901 195.556 1.9E-44 -0.158841 26.2 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs547113723 189.721 0.912880880704 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 7:2296552:A:G 7 2296552 G A 0.00376671 0.988495 53.8199 2.2E-13 0.118289 24.4 SNX8 missense won rs2950627 0.000444496043108 57.5561 0.00041564200129 -0.0152677 51.5744447775 rs28522260 133.593 0.000122389969 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_HDLcholesterol_v2 7:75610876:C:T 7 75610876 T C 0.00469227 0.914618 29.8028 4.8E-08 0.0808577 25.0 POR missense lost 7:75615439:C:G 1.05628926542 35.0825 0.897324241984 0.0808178 0.0229654737432 7:77353261_AT_A 46.3016 0.00011177775625 POR 0.0001 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 8:19362707:C:G 8 19362707 G C 0.00163269 0.925238 37.5484 8.9E-10 0.149578 LOW NONE N/A lost 8:19363435:C:T 1.02075858693 38.5553 0.994100726116 0.152195 0.00400363096368 8:19824667:C:T 4430.64 0.00119015340196 CSGALNACT1 0.0004 0.0000 0.0003 0.5181 biochemistry_HDLcholesterol_v2 8:19809316:G:C 8 19809316 C G 0.000120314 0.974078 30.6518 3.1E-08 -0.475539 26.6 LPL missense lost rs12542766 0.00840557758966 1304.55 0.00019749805156 -0.0694246 25.2890132842 rs6989064 1729.7 0.00013814241156 LPL 0.0062 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 8:19811733:G:A 8 19811733 A G 0.000434276 0.837003 346.898 2.0E-77 -0.919948 23.3 LPL missense won rs7826306 0.00396363610926 2093.99 0.00065663037504 -0.0901938 304.59337471 8:19824667:C:T 4430.64 0.00014851809424 LPL 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 8:19813594:G:A 8 19813594 A G 6.4497e-05 0.838027 64.4751 9.8E-16 -1.05995 28.6 LPL missense won rs181349205 0.102156633483 836.085 0.00787785830329 0.321594 29.846658955 8:19813529:A:G 2010.17 0.00304923735601 LPL 0.0000 0.0000 0.0058 0.6289 biochemistry_HDLcholesterol_v2 8:30469817:T:C 8 30469817 C T 0.00665603 0.963237 32.3947 1.3E-08 0.0714558 24.9 GTF2E2 missense won N/A N/A N/A N/A N/A N/A rs77629603 30.4364 0.474860188201 GTF2E2 0.0000 0.0000 0.0025 0.0035 biochemistry_HDLcholesterol_v2 8:31012237:C:G 8 31012237 G C 0.00716354 0.906853 30.0942 4.1E-08 0.0650099 25.5 WRN missense lost rs77629603 0.879958950787 30.4364 0.870065469529 -0.0716701 0.115453568724 8:30469817:T:C 32.3947 0.472674125169 WRN 0.0048 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107555451:C:T 9 107555451 T C 1.50992e-05 0.901866 55.1996 1.1E-13 -1.92489 34 ABCA1 splice_donor won rs2777806 0.00106755507858 301.013 0.00019576766889 0.0611157 51.6514046157 rs2777803 366.445 0.00014712962209 ABCA1 0.0443 0.0000 0.0438 0.9967 biochemistry_HDLcholesterol_v2 9:107556776:T:G 9 107556776 G T 0.000341518 0.861164 386.831 4.1E-86 -1.08189 28.9 ABCA1 missense won rs10125482 0.00268854374202 1040.3 0.00099972321856 0.0955247 347.755732839 rs2740488 1555.62 0.00033994509376 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107558471:T:C 9 107558471 C T 0.000214246 0.933543 97.8491 4.5E-23 0.667936 22.5 ABCA1 missense won rs2254884 0.000610272812005 111.25 0.00053676085761 -0.0234644 93.0743449495 rs2254884 111.25 0.00053676085761 ABCA1 0.0465 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107560784:C:T 9 107560784 T C 0.000643008 0.88197 152.356 5.3E-35 -0.496319 34 ABCA1 missense won rs3905001 0.000559245603348 456.586 0.00018661199236 -0.0450802 145.235261017 rs3905001 456.586 0.00018661199236 ABCA1 0.0038 0.0000 0.0568 0.0000 biochemistry_HDLcholesterol_v2 9:107562145:T:C 9 107562145 C T 0.000116121 0.903681 128.788 7.5E-30 -1.06614 24.4 ABCA1 missense won 9:107665978:C:G 0.0036367154444 681.967 0.00068678588356 -0.0774514 113.72319675 rs2740488 1555.62 0.00023597260996 ABCA1 0.0002 0.0000 0.0049 0.0027 biochemistry_HDLcholesterol_v2 9:107571746:C:A 9 107571746 A C 2.82609e-05 0.923006 32.2835 1.3E-08 -1.01928 34 ABCA1 splice_donor lost rs148681264 0.00432031757275 84.2757 0.00165498444225 0.0746466 28.1790427061 9:107665978:C:G 681.967 0.00015370544484 ABCA1 0.0000 0.0000 0.0997 0.9970 biochemistry_HDLcholesterol_v2 9:107573080:C:A 9 107573080 A C 1.37243e-05 1 42.469 7.2E-11 -1.6114 LOW NONE N/A won N/A N/A N/A N/A N/A N/A N/A N/A N/A ABCA1 0.0268 0.0000 0.3002 0.9956 biochemistry_HDLcholesterol_v2 9:107574868:C:T 9 107574868 T C 2.53692e-05 0.851612 41.3116 1.3E-10 -1.2528 33 ABCA1 missense won 9:107666035:G:GC 0.00250075815562 631.276 0.00016365317329 -0.0773179 37.2831239557 9:107665978:C:G 681.967 0.000126810121 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107578620:G:A 9 107578620 A G 0.00195775 0.918027 87.9553 6.7E-21 -0.211585 23.9 ABCA1 missense won rs2777800 0.0250527633108 292.35 0.00753727830625 -0.0429682 62.3155796773 9:107666414:T:C 878.354 0.00124984875024 ABCA1 0.0416 0.0005 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107581111:C:A 9 107581111 A C 1.92532e-05 0.803005 36.9603 1.2E-09 -1.47059 33 ABCA1 missense won rs57320838 0.00402500075606 47.4623 0.00313438740736 0.102873 32.4193284703 rs57320838 47.4623 0.00313438740736 ABCA1 0.0007 0.0000 0.0015 0.0000 biochemistry_HDLcholesterol_v2 9:107583726:T:C 9 107583726 C T 2.43613e-05 0.941877 31.6632 1.8E-08 -1.15822 23.9 ABCA1 missense lost 9:107593919:T:A 0.938041665151 46.2033 0.642841547076 -1.13573 0.0313669422488 9:107592356:C:T 67.2293 0.00032573391361 ABCA1 0.0002 0.0000 0.0001 0.0000 biochemistry_HDLcholesterol_v2 9:107588169:CTG:C 9 107588169 C CTG 0.000131896 0.929249 94.2913 2.7E-22 -0.86611 25.8 ABCA1 splice_acceptor won rs2275542 0.00100301498844 482.37 0.00019606440529 0.0454704 88.4133869724 rs12001061 582.039 0.00015538370409 N/A N/A N/A N/A N/A biochemistry_HDLcholesterol_v2 9:107593272:G:A 9 107593272 A G 6.47759e-05 0.844356 52.5984 4.1E-13 -0.852108 26.4 ABCA1 missense won N/A N/A N/A N/A N/A N/A rs75242419 43.7597 0.00065321647561 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107593329:C:A 9 107593329 A C 0.000178475 0.816695 257.501 6.0E-58 -1.25762 28.6 ABCA1 missense won rs151158579 0.00805537425432 343.983 0.006030143716 0.121366 213.352942983 rs2740488 1555.62 0.00041551153281 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107593339:G:A 9 107593339 A G 4.48964e-05 0.842989 109.755 1.1E-25 -1.52071 31 ABCA1 missense won rs4100654 0.00366417504004 1085.95 0.000370331536 0.109225 96.8696878978 rs13284054 1122.93 0.00026136218889 ABCA1 0.0363 0.0006 0.0001 0.0000 biochemistry_HDLcholesterol_v2 9:107593919:T:A 9 107593919 A T 3.72196e-05 0.961955 46.2033 1.1E-11 -1.13573 29.4 ABCA1 missense won 9:107592356:C:T 0.000763622824275 67.2293 0.00052479937225 -0.0362883 43.68504321 9:107592356:C:T 67.2293 0.00052479937225 ABCA1 0.0000 0.0000 0.0000 0.0000 biochemistry_HDLcholesterol_v2 9:107646756:G:A 9 107646756 A G 0.00134503 0.835804 58.9445 1.6E-14 -0.217945 25.0 ABCA1 missense won rs36050540 0.00196995763842 355.386 0.00032673816081 -0.0431151 53.8282086448 rs4149307 818.764 0.000105842944 ABCA1 0.0004 0.0000 0.0000 0.0005 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_IGF1_v2 11:46702070:G:A 11 46702070 A G 0.00846316 0.990294 34.384 4.5E-09 0.0601418 22.1 ARHGAP1 missense lost rs141813932 1.00597463305 35.4851 0.974759315401 -0.0617279 0.000305931646023 rs7131605 347.327 0.0161772961 ARHGAP1 0.0155 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 12:103306579:C:T 12 103306579 T C 0.00085861 0.905401 56.1522 6.7E-14 0.25718 25.0 PAH missense lost rs567778228 1.13103319853 314.794 0.201750993889 -0.907646 0.226422888646 rs775443870 601.827 0.00010624249476 PAH 0.0000 0.0000 0.0006 0.0010 biochemistry_IGF1_v2 12:104152932:G:A 12 104152932 A G 0.00119408 0.973357 35.7629 2.2E-09 -0.166879 22.9 STAB2 missense won rs74900775 0.00029202768646 48.2649 0.0002163841 0.0347161 34.5510524081 12:102059800:T:C 51.7138 0.00010364054416 STAB2 0.0011 0.0015 0.0000 0.0000 biochemistry_IGF1_v2 12:109661672:A:G 12 109661672 G A 0.0019818 0.775439 32.4157 1.2E-08 -0.135185 24.1 ACACB missense won rs7398796 0.000299210821366 47.2041 0.00020547215649 -0.0154752 31.3039642782 rs7952972 67.0467 0.00011911321321 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 12:121176971:C:T 12 121176971 T C 0.000367773 0.526499 31.1251 2.4E-08 0.39269 25.8 ACADS missense lost rs774263511 0.154591874005 213.887 0.022496400144 -0.166843 11.4611461138 12:121416864:C:T 641.769 0.00463981670244 ACADS 0.0183 0.0000 0.0008 0.0000 biochemistry_IGF1_v2 14:60976501:G:A 14 60976501 A G 0.00684529 0.967579 38.8628 4.5E-10 0.0743397 31 SIX6 missense lost 14:60847438_GAAGA_G 0.0192123363449 76.8814 0.00971164917529 0.0181208 28.8360107294 14:60847438_GAAGA_G 76.8814 0.00971164917529 SIX6 0.0000 0.0000 0.0024 0.0000 biochemistry_IGF1_v2 14:64676751:C:T 14 64676751 T C 0.00921304 0.978949 55.1493 1.1E-13 -0.0737487 24.7 SYNE2 missense won N/A N/A N/A N/A N/A N/A rs181250249 50.7907 0.949492387561 SYNE2 0.0001 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 15:62360122:G:C 15 62360122 C G 0.00127388 0.854988 39.534 3.2E-10 -0.187236 28.3 C2CD4A missense won rs62008555 0.00380214371317 191.96 0.000783048289 -0.0270389 34.8088604602 15:62411924_GT_G 197.702 0.00070228180036 C2CD4A 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 15:62360174:T:C 15 62360174 C T 0.00309366 0.942326 127.582 1.4E-29 -0.194383 25.7 C2CD4A missense won rs36055710 0.0141285421931 199.089 0.00905397922576 0.0324376 99.0548502206 rs17205463 384.744 0.003597480441 C2CD4A 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1129586:C:T 16 1129586 T C 0.00119193 0.882992 98.8247 2.8E-23 0.29136 23.4 SSTR5 missense won rs2076421 0.00557072510057 393.802 0.00139797471025 -0.0388574 84.6232095951 rs55828954 772.328 0.00011896919329 SSTR5 0.0004 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1265283:T:C 16 1265283 C T 0.000382463 0.897688 38.3563 5.9E-10 -0.317514 25.4 CACNA1H missense lost 16:1536082:C:T 0.925397154016 38.5161 0.921557760484 -0.311273 0.0554574978312 16:1129010:C:A 1420.85 0.00455926099729 CACNA1H 0.0005 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1395257:C:T 16 1395257 T C 0.00236418 0.927924 43.8654 3.5E-11 -0.133089 22.5 BAIAP3 missense lost rs185731335 0.805872554964 82.0331 0.430922663809 0.176474 0.459027816603 16:1129010:C:A 1420.85 0.000294534244 BAIAP3 0.0276 0.0122 0.0000 0.0000 biochemistry_IGF1_v2 16:1536082:C:T 16 1536082 T C 0.00037196 0.971827 38.5161 5.4E-10 -0.311273 23.2 PTX4 missense lost 16:1129010:C:A 0.153031736921 1420.85 0.00414835181929 -0.158984 14.2758505516 16:1129010:C:A 1420.85 0.00414835181929 PTX4 0.0010 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1718110:C:T 16 1718110 T C 0.0096882 0.983362 55.9752 7.3E-14 -0.0760257 24.7 CRAMP1L missense lost rs12927818 0.989765790117 56.7885 0.9755907984 0.0773454 0.00147324579212 rs55828954 772.328 0.00025973834896 LA16c-431H6.6 0.0001 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1828030:G:A 16 1828030 A G 0.00667368 0.933647 71.694 2.5E-17 -0.102979 23.6 SPSB3 missense lost rs187807665 0.203921835486 140.208 0.104273451396 0.0535373 21.5632414883 16:1129010:C:A 1420.85 0.00014994737209 SPSB3 0.0289 0.0035 0.0001 0.0000 biochemistry_IGF1_v2 16:1840636:G:A 16 1840636 A G 6.25906e-05 0.87234 48.2093 3.8E-12 -0.926887 25.4 IGFALS missense won rs187807665 0.0026020314781 140.208 0.00089468586769 0.0535373 43.4164185768 rs1065656 644.504 0.00012307017969 IGFALS 0.0000 0.0000 0.0001 0.0000 biochemistry_IGF1_v2 16:1840640:G:C 16 1840640 C G 0.000164671 0.901554 47.4207 5.7E-12 -0.550412 22.5 IGFALS missense lost 16:1842109:T:G 0.98550568785 75.1601 0.621784292089 -0.884399 0.00250881036664 rs1065656 644.504 0.00034032501441 IGFALS 0.0029 0.0000 0.0001 0.0000 biochemistry_IGF1_v2 16:1840711:C:T 16 1840711 T C 0.00205447 0.981229 103.704 2.3E-24 -0.214646 24.4 IGFALS missense won rs147400256 0.161848509793 206.942 0.081106483264 0.101593 37.0472694725 rs1065656 644.504 0.00462273528649 IGFALS 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1840741:G:A 16 1840741 A G 7.88438e-05 0.926315 48.2096 3.8E-12 -0.780414 26.2 IGFALS missense won 16:1115377:C:T 0.000911953228147 438.158 0.000100340289 -0.0424128 45.3418435814 16:1115377:C:T 438.158 0.000100340289 IGFALS 0.0028 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1840935:T:TC 16 1840935 TC T 3.61848e-05 0.79186 34.3441 4.6E-09 -1.0102 26.1 IGFALS frameshift won rs3751828 0.00235148152706 387.273 0.00020853381649 0.0555618 31.0940260367 16:1814964:C:T 424.621 0.00012853437129 N/A N/A N/A N/A N/A biochemistry_IGF1_v2 16:1841296:G:A 16 1841296 A G 0.000631097 0.702138 37.3613 9.8E-10 -0.285724 21.8 IGFALS missense lost rs55828954 0.051197500855 772.328 0.00247667466244 0.0892628 22.3667235468 rs55828954 772.328 0.00247667466244 IGFALS 0.0009 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1841325:G:A 16 1841325 A G 0.000297929 0.854066 143.979 3.6E-33 -0.714687 25.9 IGFALS missense won 16:1129010:C:A 0.00233265805651 1420.85 0.00023637525025 -0.158984 130.407173799 16:1129010:C:A 1420.85 0.00023637525025 IGFALS 0.0002 0.0000 0.0001 0.0000 biochemistry_IGF1_v2 16:1841521:T:C 16 1841521 C T 4.87866e-05 0.911014 32.6492 1.1E-08 -0.841303 24.6 IGFALS missense won 16:1814019:G:C 0.00102857506891 221.234 0.00015179472025 -0.0352372 30.5885706697 16:1814019:G:C 221.234 0.00015179472025 IGFALS 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1841532:C:T 16 1841532 T C 7.84746e-05 0.739333 34.7071 3.8E-09 -0.765273 24.9 IGFALS missense won rs559777878 0.000228533538661 66.2786 0.00011967266025 0.0232988 33.6656746614 rs559777878 66.2786 0.00011967266025 IGFALS 0.0014 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1841689:G:A 16 1841689 A G 0.000152532 0.663339 46.1116 1.1E-11 -0.667656 23.7 IGFALS missense won rs8048693 0.0021720871549 591.588 0.00016930433689 0.0493372 41.9136356957 rs8048693 591.588 0.00016930433689 IGFALS 0.0002 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1841905:G:A 16 1841905 A G 8.11039e-05 0.745674 72.6559 1.5E-17 -1.03767 25.1 IGFALS missense won N/A N/A N/A N/A N/A N/A 16:2004082:C:T 51.9066 0.692288897521 IGFALS 0.0006 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1842069:G:A 16 1842069 A G 6.22844e-05 0.795202 33.5514 6.9E-09 -0.749927 22.6 IGFALS missense won 16:1814964:C:T 0.00243988905574 424.621 0.00019278767104 -0.0506204 30.3187032441 rs1065656 644.504 0.00011749909609 IGFALS 0.0065 0.0000 0.0006 0.0000 biochemistry_IGF1_v2 16:1842109:T:G 16 1842109 G T 0.00010371 0.85879 75.1601 4.3E-18 -0.884399 23.0 IGFALS missense won rs3751828 0.00301482500541 387.273 0.00058510288321 0.0555618 67.1329998722 rs1065656 644.504 0.00019350757449 IGFALS 0.0256 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:1842146:C:CGGGG 16 1842146 CGGGG C 9.85142e-05 0.881669 71.8596 2.3E-17 -0.883722 23.3 IGFALS frameshift won rs112720618 0.000337637062265 101.85 0.00023821761649 0.0217155 69.2430360972 rs112720618 101.85 0.00023821761649 N/A N/A N/A N/A N/A biochemistry_IGF1_v2 16:1842232:T:C 16 1842232 C T 0.000282504 0.902835 34.3298 4.7E-09 -0.335856 23.1 IGFALS missense lost rs371803531 0.462027604727 45.4327 0.349116721321 0.219274 3.52139142687 rs1065656 644.504 0.000605209201 IGFALS 0.0038 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:2004082:C:T 16 2004082 T C 4.49057e-05 0.805102 51.9066 5.8E-13 -1.14451 21.1 RPL3L missense lost 16:1841905:G:A 0.969026538232 72.6559 0.692288897521 -1.03767 0.0126458311934 16:1841905:G:A 72.6559 0.692288897521 RPL3L 0.0003 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:2810375:C:T 16 2810375 T C 8.0307e-05 0.9606 31.286 2.2E-08 -0.624326 22.3 SRRM2 missense lost 16:2814602:C:T 1.01579833539 32.2477 0.985504911076 -0.627982 0.00193687810928 16:1814964:C:T 424.621 0.00013256068225 SRRM2 0.0002 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 16:2814602:C:T 16 2814602 T C 8.30354e-05 0.939179 32.2477 1.4E-08 -0.627982 22.4 SRRM2 missense lost 16:1842069:G:A 0.521487695246 33.5514 0.501224352784 -0.749927 2.48970291173 16:1814964:C:T 424.621 0.00012776685156 SRRM2 0.0002 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 17:7534678:C:T 17 7534678 T C 0.00691642 0.973007 31.4497 2.0E-08 -0.0658811 23.4 SHBG missense lost 17:7529902:G:A 0.125890062061 45.8565 0.086339007225 -0.0264391 13.0915751335 rs753841629 91.3564 0.0226893969 SHBG 0.0000 0.0000 0.0356 0.0012 biochemistry_IGF1_v2 19:49969006:C:G 19 49969006 G C 0.00105663 0.760556 40.0153 2.5E-10 0.2021 24.0 ALDH16A1 missense won rs204248 0.000575577625039 105.71 0.00021787826449 -0.0214598 38.118301868 rs546308 153.006 0.00012150211984 CTD-3148I10.9 0.1002 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 20:35885268:CAAAG:C 20 35885268 C CAAAG 8.06627e-05 0.917016 48.5994 3.1E-12 -0.767611 23.5 GHRH frameshift won 20:33447162:G:A 0.000457468187519 98.6067 0.00022546824336 -0.0263098 46.5426955656 20:33447162:G:A 98.6067 0.00022546824336 N/A N/A N/A N/A N/A biochemistry_IGF1_v2 20:54824557:C:A 20 54824557 A C 0.00191823 0.940384 34.4404 4.4E-09 -0.130514 22.9 MC3R missense lost rs1886955 0.97810926228 37.3623 0.901616716225 -0.13105 0.00417178585444 rs2104476 80.5895 0.00010472247556 MC3R 0.0036 0.0000 0.0024 0.0000 biochemistry_IGF1_v2 22:29196469:G:A 22 29196469 A G 0.00479997 0.853696 31.2945 2.2E-08 -0.0858274 22.4 XBP1 missense lost rs80311519 0.619790895451 31.3362 0.618966121536 0.0789831 1.41622965853 22:29449477:A:G 49.225 0.00399932289604 XBP1 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 22:46627780:C:T 22 46627780 T C 0.00621137 0.913845 40.0151 2.5E-10 0.0811034 21.5 PPARA missense won N/A N/A N/A N/A N/A N/A rs146471363 30.6926 0.640742615296 PPARA 0.0000 0.0000 0.0004 0.0000 biochemistry_IGF1_v2 2:25384048:G:C 2 25384048 C G 0.00595558 0.926148 37.909 7.4E-10 0.0795859 28.7 POMC missense lost rs186080745 0.60161942363 39.0426 0.584151432804 -0.105369 1.90821877581 rs4289132 527.38 0.00080227730025 POMC 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 3:52022837:C:T 3 52022837 T C 0.00393562 0.906022 98.6114 3.1E-23 0.162013 25.5 ABHD14A-ACY1 missense won N/A N/A N/A N/A N/A N/A rs558897400 47.8899 0.333931425424 ACY1 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 3:169831268:T:C 3 169831268 C T 0.00714507 0.945113 67.6476 2.0E-16 -0.0981078 25.5 PHC3 missense won rs6792686 0.000500178587879 85.1149 0.00039753181924 -0.0185139 64.6556030064 rs61793868 101.644 0.000164788569 PHC3 0.0745 0.0000 0.0056 0.0000 biochemistry_IGF1_v2 3:172165413:AT:A 3 172165413 A AT 0.000180595 0.852891 46.5396 9.0E-12 -0.514681 35 GHSR frameshift won rs582780 0.00100920506199 385.63 0.00012179550321 -0.0387467 43.6296290906 rs582780 385.63 0.00012179550321 N/A N/A N/A N/A N/A biochemistry_IGF1_v2 4:155489608:C:T 4 155489608 T C 0.00593382 0.942434 44.6964 2.3E-11 0.0842539 25.2 FGB missense won 4:154519658:A:G 0.000438058731281 45.1628 0.00043353486225 -0.0146821 42.8450015177 4:154519658:A:G 45.1628 0.00043353486225 FGB 0.0001 0.0000 0.0018 0.0004 biochemistry_IGF1_v2 7:6623017:T:C 7 6623017 C T 0.00968182 0.948668 35.2579 2.9E-09 -0.062225 25.3 ZDHHC4 missense lost rs184536742 0.827091329937 49.7194 0.586521627409 0.064054 0.289118175853 rs75165920 293.672 0.052862746561 ZDHHC4 0.0138 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 7:45954519:C:T 7 45954519 T C 0.000151389 0.933879 43.6361 4.0E-11 -0.518586 32 IGFBP3 missense won rs113136672 0.0105986522077 138.866 0.00333043255801 0.0569696 35.1139321744 rs2345706 729.64 0.00010526965201 IGFBP3 0.0004 0.0001 0.0000 0.0000 biochemistry_IGF1_v2 7:45956185:G:C 7 45956185 C G 8.43005e-05 0.866717 87.9858 6.6E-21 -1.03519 25.8 IGFBP3 missense won 7:45829288_TA_T 0.000829473954241 119.357 0.00061145914729 0.0376519 82.9906961182 7:45966264_TC_T 417.79 0.00010575242896 IGFBP3 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 7:47331594:G:A 7 47331594 A G 0.00979948 0.933109 30.773 2.9E-08 0.0570454 25.3 TNS3 missense lost rs13227267 0.669254863841 262.845 0.078354086724 -0.120485 1.01842909356 rs700750 3498.72 0.001960364176 TNS3 0.0000 0.0048 0.0000 0.0000 biochemistry_IGF1_v2 8:15967628:T:C 8 15967628 C T 0.00258515 0.924441 37.1376 1.1E-09 -0.126478 23.7 MSR1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A MSR1 0.0000 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 9:5126343:G:A 9 5126343 A G 0.00555287 0.935982 42.0036 9.1E-11 -0.0878743 24.8 JAK2 missense won rs296854 0.00361610839295 54.0431 0.00281052660736 -0.0193429 37.1037933155 rs439975 181.512 0.00046199633481 JAK2 0.0022 0.0000 0.0000 0.0000 biochemistry_IGF1_v2 9:128434756:T:C 9 128434756 C T 0.000297731 0.848377 34.6843 3.9E-09 0.372893 24.9 MAPKAP1 missense lost rs753720625 0.936843135755 36.6445 0.886729205569 -0.365233 0.0357244127982 9:128399680_TAA_T 94.6515 0.00015681050176 MAPKAP1 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_LDLdirect_v2 10:52573772:C:T 10 52573772 T C 0.00987044 0.962839 47.715 4.9E-12 0.0729367 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs144458455 35.623 0.451747982884 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 11:116701354:G:A 11 116701354 A G 0.00222875 0.92045 60.9463 5.9E-15 -0.166469 31 APOC3 splice_donor won rs180327 0.00273746670949 169.28 0.00098557695721 0.0264338 54.735619426 11:116648917:C:G 454.586 0.00024555830209 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_LDLdirect_v2 17:7077063:C:G 17 7077063 G C 0.00022889 0.876384 35.2336 2.9E-09 -0.471966 26.2 ASGR1 missense lost 17:7160171:TC:T 0.984790096639 35.3139 0.982550790169 -0.480222 0.00205339133535 rs3744263 38.459 0.00011936436516 ASGR1 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:11213450:G:A 19 11213450 A G 3.4347e-05 0.927448 39.9369 2.6E-10 1.15073 24.1 LDLR missense won 19:11190764:G:A 0.00132312286914 114.677 0.00046078486281 0.0428167 37.0843514453 19:11190764:G:A 114.677 0.00046078486281 LDLR 0.0000 0.0000 0.0022 0.0012 biochemistry_LDLdirect_v2 19:11218182:A:C 19 11218182 C A 7.7348e-05 0.959902 33.9412 5.7E-09 0.624815 22.7 LDLR missense won 19:11170677:A:G 0.00357302677869 36.1295 0.00335661485769 0.0449674 30.0048158968 rs564282752 359.75 0.00016903640196 LDLR 0.0000 0.0000 0.0005 0.0006 biochemistry_LDLdirect_v2 19:11224296:G:A 19 11224296 A G 8.00802e-05 0.81432 78.8424 6.7E-19 1.15563 29.8 LDLR missense won rs7251031 0.000722226958985 374.39 0.00015209302276 -0.0423231 74.6616765417 19:11275139:A:C 436.091 0.00011445148324 LDLR 0.0005 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:11227645:G:T 19 11227645 T G 0.000457426 0.847841 41.2496 1.3E-10 0.33522 20.1 LDLR missense won rs17842117 0.00677331427181 79.2489 0.00352555687696 -0.0322271 34.7393001791 rs5742911 703.461 0.00017631856225 LDLR 0.0001 0.0000 0.0127 0.0003 biochemistry_LDLdirect_v2 19:11231112:C:T 19 11231112 T C 4.03362e-05 0.776697 42.8066 6.0E-11 1.21691 25.8 LDLR missense lost 19:9490773:G:A 0.855917597583 49.0678 0.746699917924 1.22744 0.239772733151 19:9490773:G:A 49.0678 0.746699917924 LDLR 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:11312671:C:T 19 11312671 T C 0.00194678 0.854536 56.7997 4.8E-14 -0.175941 26.6 DOCK6 missense lost rs747875948 0.516346503913 3134.21 0.00935748610281 0.177518 4.49861643244 rs12151108 3228.6 0.00891925358724 DOCK6 0.0005 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:44932609:G:A 19 44932609 A G 0.000613015 0.747139 45.9736 1.2E-11 -0.312372 23.3 ZNF229 missense lost rs1065853 0.958895496403 16860.5 0.00261462459556 0.478183 0.019828683405 rs1065853 16860.5 0.00261462459556 ZNF229 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:44932910:C:CT 19 44932910 CT C 0.00542772 0.981222 151.113 9.9E-35 -0.166803 34 ZNF229 frameshift lost rs367866106 0.997478137035 1341.0 0.112402620225 0.485131 0.000240565275012 rs1065853 16860.5 0.012430689049 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 19:45322904:C:T 19 45322904 T C 0.00200212 0.972321 31.3168 2.2E-08 0.128389 25.1 BCAM missense lost rs814573 0.898430071118 4323.51 0.00650766503401 -0.172991 0.0851518716608 rs1065853 16860.5 0.00011395349001 BCAM 0.0002 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 19:45391526:G:A 19 45391526 A G 0.000292833 0.771006 74.8762 5.0E-18 -0.590429 25.1 PVRL2 missense lost rs1065853 0.495177852543 16860.5 0.002199047236 0.478183 6.5741572182 rs1065853 16860.5 0.002199047236 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 19:45404058:C:T 19 45404058 T C 0.00179961 0.927388 62.8676 2.2E-15 0.193807 25.2 TOMM40 missense lost 19:45385421:T:C 1.05791546957 70.1481 0.948117006369 0.202926 0.0512441784786 rs1065853 16860.5 0.00016037436321 TOMM40 0.0000 0.0000 0.0003 0.0000 biochemistry_LDLdirect_v2 19:45567745:G:GTCCCGC 19 45567745 GTCCCGC G 0.0071278 0.906612 79.1445 5.8E-19 0.10526 20.3 CLASRP inframe_insertion lost 19:45496095:C:T 0.605747588381 131.37 0.364935601801 0.209101 3.89009704721 19:45411941:T:C 4831.02 0.003107616516 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 19:45641786:G:A 19 45641786 A G 0.00177449 0.881007 86.7737 1.2E-20 -0.240366 23.0 PPP1R37 missense lost rs112450640 0.885755723011 2739.54 0.028055915001 0.384721 0.300566543564 rs1065853 16860.5 0.00734275896201 PPP1R37 0.0074 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:55505598:G:GCGCA 1 55505598 GCGCA G 7.54234e-05 0.895178 74.3378 6.6E-18 -1.07444 23.4 PCSK9 frameshift won rs545634492 0.00127990858913 86.8069 0.00109606020624 0.0373213 69.1139555549 rs2479410 255.846 0.00010106079841 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 1:55512267:C:A 1 55512267 A C 0.000101767 0.941969 58.2513 2.3E-14 -0.787279 24.1 PCSK9 missense won rs4927205 0.00399120963852 199.538 0.00116515726336 0.0529759 51.1236224374 1:55719166:T:G 279.736 0.00015857609329 PCSK9 0.0003 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:55518085:G:T 1 55518085 T G 0.00014506 0.952882 122.213 2.1E-28 -0.939204 28.2 PCSK9 splice_donor won rs200730299 0.00243830217926 437.422 0.00068124654049 0.0556167 110.441439838 rs200730299 437.422 0.00068124654049 PCSK9 0.0002 0.0000 0.8531 0.9899 biochemistry_LDLdirect_v2 1:55518374:C:T 1 55518374 T C 0.00130584 0.813031 224.728 8.4E-51 -0.44659 24.4 PCSK9 missense won N/A N/A N/A N/A N/A N/A 1:55493843_CG_C 173.127 0.00027169917889 PCSK9 0.0002 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:55524201:T:C 1 55524201 C T 0.000350087 0.836139 111.661 4.2E-26 -0.643837 21.7 PCSK9 missense won rs4927207 0.00293660541635 230.813 0.00142064917225 0.0437483 99.8869834992 rs17111503 341.817 0.00010617035521 PCSK9 0.0014 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:55524309:G:A 1 55524309 A G 0.000350549 0.815522 155.738 9.7E-36 -0.73929 23.0 PCSK9 missense won rs10888896 0.000875752905241 214.245 0.00063659831481 -0.0340187 146.656840551 rs499883 354.247 0.00037040081764 PCSK9 0.0000 0.0000 0.0001 0.0000 biochemistry_LDLdirect_v2 1:55527230:G:A 1 55527230 A G 0.000321895 0.972056 303.87 4.7E-68 -0.981343 23.8 PCSK9 splice_donor won N/A N/A N/A N/A N/A N/A 1:55719166:T:G 279.736 0.00046000383529 PCSK9 0.0004 0.0000 0.5440 0.9807 biochemistry_LDLdirect_v2 1:63063592:GAACTC:G 1 63063592 G GAACTC 0.000621911 0.889289 76.3141 2.4E-18 -0.358847 34 ANGPTL3 frameshift won rs370129568 0.000698665758771 165.598 0.00032197278096 -0.0295568 72.3331057695 rs370129568 165.598 0.00032197278096 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 1:63069706:T:G 1 63069706 G T 0.000411814 0.870862 60.1359 8.9E-15 -0.399222 26.5 ANGPTL3 missense won 1:63131385_CAA_C 0.000602002795769 60.5837 0.00059755313601 0.020292 57.2211437324 1:63130453_TA_T 87.2269 0.00012004927489 DOCK7 0.0064 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:109793077:C:A 1 109793077 A C 0.00613297 0.975014 37.1428 1.1E-09 -0.0823816 23.0 CELSR2 missense lost rs17035949 1.04934839956 292.676 0.133170255625 0.0866847 0.0220718106672 1:109817192:A:G 2577.33 0.0206008609 CELSR2 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 1:110020621:A:G 1 110020621 G A 0.00556527 0.940413 39.8489 2.7E-10 -0.0924882 25.3 SYPL2 missense lost rs570439166 0.936173953567 40.3878 0.923682455056 0.0927487 0.0419329957797 1:109817192:A:G 2577.33 0.014260897561 SYPL2 0.0000 0.0000 0.0002 0.0762 biochemistry_LDLdirect_v2 1:110050180:C:T 1 110050180 T C 0.00696354 0.964489 40.9648 1.5E-10 -0.0757133 22.5 AMIGO1 missense lost rs181344473 0.984035358752 45.2658 0.890535717124 0.0835319 0.00263121776584 1:109817192:A:G 2577.33 0.018037833025 AMIGO1 0.0001 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21228431:A:C 2 21228431 C A 6.05155e-05 0.814739 30.59 3.2E-08 -0.772018 24.2 APOB missense lost rs35098041 0.00706015792305 1317.56 0.000163916809 -0.0895507 25.6653362769 rs35098041 1317.56 0.000163916809 APOB 0.0182 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21228587:G:C 2 21228587 C G 1.8802e-05 0.805907 83.4811 6.4E-20 -2.44806 35 APOB stop_gained won rs36134738 0.000957372751261 459.604 0.00017389433161 0.0848246 78.3949715235 rs36134738 459.604 0.00017389433161 APOB 0.0000 0.0000 0.0001 0.0000 biochemistry_LDLdirect_v2 2:21228891:CA:C 2 21228891 C CA 0.000147343 0.642863 401.215 3.0E-89 -2.05564 25.3 APOB frameshift won 2:21232804:G:A 0.000527533529607 1664.48 0.00012715945225 0.0815181 382.996363419 2:21232804:G:A 1664.48 0.00012715945225 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 2:21229068:G:A 2 21229068 A G 0.00108238 0.934139 83.0821 7.9E-20 0.284865 26.1 APOB missense won rs112507407 0.0633723843604 262.162 0.020083424656 -0.0850048 46.5172473565 rs581411 1702.54 0.00019020547225 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21229160:C:T 2 21229160 T C 0.000359208 0.96006 361.451 1.4E-80 1.00621 24.9 APOB missense won rs4635554 0.00191079581769 1002.89 0.00068866880625 -0.0669996 330.541696555 rs577584 1469.73 0.000101888836 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21229501:AG:A 2 21229501 A AG 3.59217e-05 0.888846 75.5279 3.6E-18 -1.5587 35 APOB frameshift won rs540156 0.000447213688317 106.243 0.00031792316416 0.0305785 72.3672355373 rs4305231 315.132 0.00010018208281 N/A N/A N/A N/A N/A biochemistry_LDLdirect_v2 2:21232176:G:A 2 21232176 A G 3.06772e-05 0.967799 153.8 2.6E-35 -2.23769 37 APOB stop_gained won rs672889 0.00115457377759 1238.51 0.000143376676 -0.100002 143.525626997 rs672889 1238.51 0.000143376676 APOB 0.0000 0.0000 0.0064 0.0000 biochemistry_LDLdirect_v2 2:21238367:C:T 2 21238367 T C 0.00514312 0.966793 194.309 3.6E-44 -0.198853 21.1 APOB missense lost rs563222733 0.533665531118 277.7 0.373410211329 0.152622 14.1101822569 2:21266774:GGCAGCGCCA:G 1788.63 0.00221159516176 APOB 0.0691 0.0437 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21242613:G:A 2 21242613 A G 0.00137071 0.895455 165.721 6.4E-38 0.359237 22.6 APOB missense won 2:21364562:C:T 0.0429635481539 268.352 0.026532174769 0.0812537 104.14082389 2:21266774:GGCAGCGCCA:G 1788.63 0.00246638377129 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_LDLdirect_v2 2:21255263:G:A 2 21255263 A G 0.000136554 0.667184 196.877 1.0E-44 -1.42115 37 APOB stop_gained won rs76611756 0.00162223752144 223.422 0.00142949779569 0.0706049 181.337147525 rs1848922 987.428 0.00025992533284 APOB 0.0000 0.0000 0.0001 0.0013 biochemistry_LDLdirect_v2 2:21256168:T:C 2 21256168 C T 4.66439e-05 0.782873 64.7859 8.3E-16 -1.28302 LOW NONE N/A won rs553448422 0.00457894476089 313.485 0.000946300644 0.0932374 56.3146993847 rs581411 1702.54 0.00012049672441 APOB 0.0006 0.0000 0.2812 0.6207 biochemistry_LDLdirect_v2 2:21260958:C:A 2 21260958 A C 2.98697e-05 0.788057 162.803 2.8E-37 -2.624 34 APOB stop_gained won rs34601365 0.000873949793783 1331.48 0.00010685977129 -0.0920503 153.319508083 rs34601365 1331.48 0.00010685977129 APOB 0.0000 0.5731 0.0142 0.0000 biochemistry_LDLdirect_v2 2:26534339:T:G 2 26534339 G T 4.48135e-05 0.681414 43.6592 3.9E-11 -1.27007 26.8 GPR113 missense won N/A N/A N/A N/A N/A N/A rs78653657 43.1207 0.000120428676 ADGRF3 0.0020 0.0000 0.0001 0.0000 biochemistry_LDLdirect_v2 2:44040341:A:G 2 44040341 G A 0.00106534 0.929326 36.5002 1.5E-09 0.192482 23.6 ABCG5 missense lost rs559411103 0.629338365879 37.0112 0.620649322969 -0.253001 1.55933887245 rs4299376 696.547 0.00077895135409 ABCG5 0.0001 0.0000 0.0003 0.0000 biochemistry_LDLdirect_v2 4:155489608:C:T 4 155489608 T C 0.00593962 0.942434 42.1859 8.3E-11 0.0868096 25.2 FGB missense won N/A N/A N/A N/A N/A N/A rs2705460 38.3458 0.00013542907876 FGB 0.0001 0.0000 0.0018 0.0004 biochemistry_LDLdirect_v2 6:160831796:G:A 6 160831796 A G 0.000935305 0.983352 52.03 5.5E-13 0.243052 20.5 SLC22A3 missense lost rs576888780 0.854984636787 52.4963 0.847390209444 -0.258017 0.295376959328 6:160575985:C:T 212.947 0.000431559076 SLC22A3 0.0003 0.0019 0.0000 0.0000 biochemistry_LDLdirect_v2 7:2296552:A:G 7 2296552 G A 0.00374188 0.988495 59.8502 1.0E-14 0.125944 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs77523736 53.0493 0.757966995769 SNX8 0.0000 0.0000 0.0000 0.0001 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_LipoproteinA_v2 17:64049981:G:C 17 64049981 C G 0.00771072 0.955778 31.2341 2.3E-08 0.0522521 31 CEP112 missense lost rs139060482 0.640630267998 71.2879 0.280685920804 -0.0469792 1.24444859188 rs149394327 285.405 0.068906775001 CEP112 0.1352 0.0353 0.0002 0.0000 biochemistry_LipoproteinA_v2 19:44932910:C:CT 19 44932910 CT C 0.00543914 0.981222 35.0226 3.3E-09 -0.0610986 34 ZNF229 frameshift lost rs144627165 0.992043400877 38.59 0.9003352996 0.0758281 0.000556514237322 rs1065853 2664.78 0.012368776225 N/A N/A N/A N/A N/A biochemistry_LipoproteinA_v2 19:45641786:G:A 19 45641786 A G 0.001757 0.881007 42.7751 6.1E-11 -0.11766 23.0 PPP1R37 missense lost rs111784051 0.489979710965 955.743 0.021929463396 0.136435 3.8501309552 rs1065853 2664.78 0.00743438848441 PPP1R37 0.0074 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 4:110638824:C:T 4 110638824 T C 0.00764713 0.943901 46.2791 1.0E-11 -0.0618169 26.2 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs189866430 45.276 0.897987454884 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 5:26881496:A:G 5 26881496 G A 1.04504e-05 0.739135 36.3049 1.7E-09 -1.66522 22.1 CDH9 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CDH9 0.0338 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:158994466:G:A 6 158994466 A G 9.9141e-05 0.996249 44.3081 2.8E-11 0.560201 33 TMEM181 missense lost rs150410901 0.911223216828 651.48 0.061973613025 -1.20924 0.0914060577526 6:161010118:A:G 82110.4 0.00028833738025 TMEM181 0.0011 0.0010 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:159029716:A:G 6 159029716 G A 4.52476e-05 0.636636 42.6067 6.7E-11 1.10927 28.6 TMEM181 missense lost rs118039278 0.229958457215 81976.3 0.00011951955625 -0.981647 11.54125088 6:161010118:A:G 82110.4 0.00011903464609 TMEM181 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:159086590:C:T 6 159086590 T C 4.09078e-05 0.964485 46.0558 1.1E-11 0.902583 39 SYTL3 stop_gained won rs41266385 0.0191871373888 2645.07 0.000334085284 -0.18714 34.1803972483 rs41266385 2645.07 0.000334085284 SYTL3 0.0000 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:159183176:C:T 6 159183176 T C 7.15675e-05 0.849333 39.2023 3.8E-10 0.650454 26.1 SYTL3 missense lost 6:160863985:C:T 0.523910281273 3314.72 0.00619614568336 0.787324 2.99024726834 6:161017363:G:A 12725.2 0.00063112995729 SYTL3 0.0000 0.0000 0.0001 0.1560 biochemistry_LipoproteinA_v2 6:159654194:C:T 6 159654194 T C 0.00786815 0.962534 36.8753 1.3E-09 -0.0551708 25.1 FNDC1 missense lost rs149976280 0.178954726189 61.4802 0.107335519641 0.182037 12.275562798 rs6938647 25580.4 0.00017193765625 FNDC1 0.0007 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:159654798:A:T 6 159654798 T A 0.000297209 0.943548 102.761 3.8E-24 0.497044 22.4 FNDC1 missense lost rs118039278 0.83599126037 81976.3 0.00104795285841 -0.981647 0.754276714114 6:161010118:A:G 82110.4 0.001043354601 FNDC1 0.0000 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:160113860:A:G 6 160113860 G A 0.000197124 0.743213 174.024 9.8E-40 0.934082 23.7 SOD2 missense lost rs12204009 0.611194516812 5195.25 0.020473031056 -0.984841 8.2863107007 6:161010118:A:G 82110.4 0.00115000339689 SOD2 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160164796:C:G 6 160164796 G C 0.000110969 0.976027 71.2187 3.2E-17 0.692513 24.6 WTAP missense lost rs142075073 0.668843004632 225.355 0.211373740516 -1.31654 2.36350336325 rs4252198 7309.54 0.00011120124304 WTAP 0.0000 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:160210450:G:C 6 160210450 C G 6.55412e-05 0.638904 32.5204 1.2E-08 0.743294 24.0 TCP1 missense lost rs145274579 0.326832205814 2319.11 0.00458310044196 -1.07388 5.96578269769 6:161010118:A:G 82110.4 0.00012621174336 TCP1 0.0000 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:160218443:G:T 6 160218443 T G 0.000991506 0.940003 183.38 8.9E-42 0.371498 22.4 MRPL18 missense lost rs534835616 0.99066980571 3170.6 0.0572979969 -1.15935 0.0040096503573 6:161010118:A:G 82110.4 0.00152346579856 MRPL18 0.0000 0.0000 0.0158 0.0000 biochemistry_LipoproteinA_v2 6:160219148:A:G 6 160219148 G A 7.63121e-05 0.896834 62.6825 2.4E-15 0.825654 25.3 MRPL18 missense lost rs118039278 0.742909433742 81976.3 0.000568059556 -0.981647 1.19507634782 6:161010118:A:G 82110.4 0.00056584039876 MRPL18 0.0000 0.0000 0.0010 0.0000 biochemistry_LipoproteinA_v2 6:160241490:T:A 6 160241490 A T 0.000871442 0.717723 88.1834 6.0E-21 0.323487 22.1 PNLDC1 missense lost rs530182985 0.562410109762 219.896 0.2255395081 -0.254432 5.5141051979 rs56393506 69878.1 0.002068157529 PNLDC1 0.0087 0.0061 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160328135:A:T 6 160328135 T A 8.35638e-05 0.552649 72.8897 1.4E-17 1.07358 23.7 MAS1 missense lost rs553449024 1.25506455239 3541.63 0.025830275524 -1.648 1.05480730202 rs783184 9520.29 0.00012138971329 MAS1 0.0000 0.0000 0.0008 0.0000 biochemistry_LipoproteinA_v2 6:160328355:T:C 6 160328355 C T 0.00108957 0.946325 45.6755 1.4E-11 -0.192958 27.8 MAS1 missense lost 6:160542909:C:T 0.995144272043 67.2108 0.676285837956 -0.234673 0.000269890965295 rs10945675 12727.9 0.00018270388224 MAS1 0.0000 0.0000 0.0011 0.0000 biochemistry_LipoproteinA_v2 6:160328358:C:T 6 160328358 T C 0.000428753 0.811246 44.7634 2.2E-11 0.309801 26.8 MAS1 missense lost rs147555597 0.801288784928 7980.21 0.00449466998929 -0.857833 0.492132285424 rs112939444 10076.1 0.00016459350436 MAS1 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160453991:G:A 6 160453991 A G 0.00181048 0.938408 34.912 3.4E-09 -0.127805 20.0 IGF2R missense lost 6:160953642:A:G 1.05381112451 1807.88 0.020350163716 -0.281138 0.0246151744971 rs12210186 15415.9 0.00023204733561 IGF2R 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160481707:G:A 6 160481707 A G 8.83196e-05 0.927292 99.3006 2.2E-23 0.924653 26.0 IGF2R missense lost rs118039278 0.742933592586 81976.3 0.000899940001 -0.981647 1.89283627998 6:161010118:A:G 82110.4 0.00089651138724 IGF2R 0.0097 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160484494:C:G 6 160484494 G C 0.00109508 0.876027 383.986 1.7E-85 0.542225 26.7 IGF2R missense lost rs529913906 0.903095955428 885.128 0.391780853776 -0.862207 0.947960619158 6:161010118:A:G 82110.4 0.00381935124081 IGF2R 0.0000 0.0000 0.0080 0.0000 biochemistry_LipoproteinA_v2 6:160489327:A:G 6 160489327 G A 0.000219009 0.882744 33.037 9.0E-09 -0.363124 22.9 IGF2R missense lost rs188218684 0.618911503527 138.365 0.147775661056 0.348665 1.50294985925 6:160872151:C:T 10874.5 0.00013470619969 IGF2R 0.0001 0.0000 0.3144 0.0000 biochemistry_LipoproteinA_v2 6:160489355:C:T 6 160489355 T C 5.40509e-05 0.885051 29.9469 4.4E-08 0.711235 22.9 IGF2R missense lost rs118039278 0.792054890812 81976.3 0.00028934690404 -0.981647 0.36252447435 6:161010118:A:G 82110.4 0.00028817778564 IGF2R 0.0000 0.0000 0.1105 0.0000 biochemistry_LipoproteinA_v2 6:160492946:C:T 6 160492946 T C 4.79909e-05 0.902096 46.521 9.1E-12 0.839478 29.6 IGF2R missense lost rs76735376 1.00813778623 14163.0 0.00331141551601 -1.05607 0.000767078614992 6:161010118:A:G 82110.4 0.00040246779456 IGF2R 0.0206 0.0015 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160494457:A:G 6 160494457 G A 3.89234e-05 0.863563 41.6277 1.1E-10 1.01637 23.6 IGF2R missense lost rs118039278 0.743380669294 81976.3 0.00037748992681 -0.981647 0.790516096424 6:161010118:A:G 82110.4 0.00037606517776 IGF2R 0.0007 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160500816:C:G 6 160500816 G C 0.000331697 0.834938 41.4252 1.2E-10 -0.305582 24.0 IGF2R missense lost rs756955314 0.97561217921 151.604 0.266582211856 0.340729 0.00623584712008 rs6938647 25580.4 0.00085287945681 IGF2R 0.0003 0.0000 0.0029 0.0005 biochemistry_LipoproteinA_v2 6:160543308:G:A 6 160543308 A G 0.000306496 0.737934 33.4988 7.1E-09 -0.316917 22.7 SLC22A1 missense lost 6:160964135:T:C 0.211652752518 3119.85 0.00227258144656 -0.178792 9.7661758436 rs4708876 10640.4 0.00018504705024 SLC22A1 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160543330:C:A 6 160543330 A C 0.000719633 0.900482 71.3129 3.0E-17 0.28368 33 SLC22A1 stop_gained lost rs185422040 0.995239023276 888.761 0.079856542921 -0.298052 0.000405075434472 rs56393506 69878.1 0.00237868847524 SLC22A1 0.0000 0.0000 0.0000 0.0193 biochemistry_LipoproteinA_v2 6:160551227:A:G 6 160551227 G A 4.84968e-05 0.704125 48.856 2.8E-12 0.939101 24.1 SLC22A1 missense lost rs147555597 0.472664284789 7980.21 0.00289371912489 -0.857833 4.77091532168 rs147555597 7980.21 0.00289371912489 SLC22A1 0.0000 0.0000 0.0000 0.0224 biochemistry_LipoproteinA_v2 6:160557643:C:T 6 160557643 T C 0.00960442 0.950395 902.968 2.2E-198 0.271102 24.0 SLC22A1 missense lost rs9295128 1.03011483243 2893.81 0.321431168601 -0.545785 0.20170030513 6:160872151:C:T 10874.5 0.00092105573121 SLC22A1 0.0031 0.0000 0.0041 0.0000 biochemistry_LipoproteinA_v2 6:160560696:CTG:C 6 160560696 C CTG 0.000479954 0.913829 31.366 2.1E-08 -0.230349 25.2 SLC22A1 frameshift lost rs41271036 1.00805895011 1117.79 0.028286866969 0.262583 0.00050723751702 6:160963010_AGAG_A 14261.6 0.00010101054016 N/A N/A N/A N/A N/A biochemistry_LipoproteinA_v2 6:160662574:C:T 6 160662574 T C 1.59314e-05 0.892523 33.644 6.6E-09 1.3898 29.2 SLC22A2 missense lost rs118039278 0.4180138394 81976.3 0.000171557604 -0.981647 4.20328097206 6:161010118:A:G 82110.4 0.00017090855824 SLC22A2 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160664688:C:T 6 160664688 T C 0.000102227 0.766935 31.0087 2.6E-08 0.507907 24.9 SLC22A2 missense lost 6:160841610_AC_A 0.556546420609 1750.53 0.00985860339025 -1.051 2.00023612806 6:161010118:A:G 82110.4 0.00010597055364 SLC22A2 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160664733:C:A 6 160664733 A C 0.000587325 0.890681 42.925 5.7E-11 -0.240555 23.5 SLC22A2 missense lost rs187631026 1.08198863454 167.023 0.278071655625 0.292593 0.06932306131 rs6938647 25580.4 0.00121240454416 SLC22A2 0.0504 0.0000 0.0189 0.0000 biochemistry_LipoproteinA_v2 6:160668329:A:C 6 160668329 C A 0.000682604 0.943366 47.1348 6.6E-12 -0.221131 26.0 SLC22A2 missense lost rs182498162 0.856770805892 230.975 0.174840223321 0.2186 0.260773811024 rs56393506 69878.1 0.00011531323456 SLC22A2 0.0092 0.0369 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:160677740:C:T 6 160677740 T C 3.27509e-05 0.777515 47.6059 5.2E-12 1.16695 26.9 SLC22A2 missense lost rs561715356 1.26154931976 278.703 0.215488138849 -1.37111 0.72242276897 6:161010118:A:G 82110.4 0.00027350875161 SLC22A2 0.0037 0.0847 0.0004 0.0000 biochemistry_LipoproteinA_v2 6:160679377:T:C 6 160679377 C T 3.24249e-05 0.56392 66.8875 2.9E-16 1.68753 34 SLC22A2 missense lost 6:161074538_AGTAATG_A 0.465375055369 5528.12 0.00563080649769 -1.27599 6.75610495348 6:161010118:A:G 82110.4 0.00013677770304 SLC22A2 0.0000 0.0000 0.0086 0.0133 biochemistry_LipoproteinA_v2 6:160679656:A:AT 6 160679656 AT A 0.00116278 0.885621 1199.63 7.3E-263 0.913225 33 SLC22A2 frameshift lost rs150044916 1.03648911206 2362.39 0.526332838144 -1.07889 0.392190149237 6:161010118:A:G 82110.4 0.010492314624 N/A N/A N/A N/A N/A biochemistry_LipoproteinA_v2 6:160819110:G:C 6 160819110 C G 2.20251e-05 0.653456 43.0171 5.4E-11 1.67581 25.8 SLC22A3 missense lost rs118039278 0.261567431706 81976.3 0.00013725762649 -0.981647 10.2679306163 6:161010118:A:G 82110.4 0.00013674028096 SLC22A3 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160831796:G:A 6 160831796 A G 0.000314316 0.983352 331.235 5.2E-74 0.909958 20.5 SLC22A3 missense lost rs562632887 0.977485259117 405.435 0.7985924496 -0.749114 0.0424561834606 rs4708876 10640.4 0.00024081763489 SLC22A3 0.0003 0.0019 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160858101:CT:C 6 160858101 C CT 3.54099e-05 0.693581 42.0153 9.1E-11 1.20509 35 SLC22A3 frameshift lost rs180925448 0.544152103039 1275.28 0.017927603236 -0.985185 2.89144171458 6:161010118:A:G 82110.4 0.00015100968996 N/A N/A N/A N/A N/A biochemistry_LipoproteinA_v2 6:160858175:G:A 6 160858175 A G 0.000781115 0.951536 71.7748 2.4E-17 -0.271015 33 SLC22A3 missense lost rs6938647 0.962470195537 25580.4 0.00270054830224 -0.347477 0.0257591330156 rs6938647 25580.4 0.00270054830224 SLC22A3 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160863796:T:A 6 160863796 A T 0.000430822 0.793203 56.5529 5.5E-14 -0.357105 21.1 SLC22A3 missense lost rs78893353 0.926862418557 1138.19 0.046052730801 0.350788 0.0785257108443 rs6938647 25580.4 0.00120489517456 SLC22A3 0.0000 0.0000 0.0001 0.0001 biochemistry_LipoproteinA_v2 6:160863809:G:C 6 160863809 C G 0.000111233 0.97667 123.572 1.0E-28 0.947779 22.7 SLC22A3 missense lost 6:161010118:A:G 0.788640790215 82110.4 0.00118686451081 0.979441 1.54857904214 6:161010118:A:G 82110.4 0.00118686451081 SLC22A3 0.0000 0.0698 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160966559:G:A 6 160966559 A G 0.000655879 0.913117 76.0846 2.7E-18 -0.299351 23.7 LPA missense won 6:160887298_GACCAGTACCAGT_G 0.0491681295034 10835.8 0.00034523869636 -0.184153 46.083709968 rs6911381 14441.7 0.00010501740484 LPA 0.0002 0.0432 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160969693:T:C 6 160969693 C T 0.00198063 0.95364 260.663 1.2E-58 -0.315104 22.7 LPA splice_acceptor won rs76037141 0.397200097858 769.899 0.134479157796 0.202676 35.6388468427 rs12210186 15415.9 0.00025178707684 LPA 0.6641 0.9817 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:160998199:G:A 6 160998199 A G 0.00229054 0.888987 193.478 5.5E-44 -0.259289 20.2 LPA missense won rs2293287 0.0240091732567 305.362 0.015212262244 0.0580473 138.164825734 6:161010150:C:T 3549.17 0.00010016206561 LPA 0.0000 0.0000 0.0667 0.0062 biochemistry_LipoproteinA_v2 6:161016523:C:T 6 161016523 T C 4.23525e-05 0.774779 46.7209 8.2E-12 0.975158 22.5 LPA missense lost rs148163986 0.580883870575 1316.09 0.020621247201 -0.794975 2.64295983877 rs79684526 3685.98 0.00130503007504 LPA 0.0000 0.0351 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161020526:A:G 6 161020526 G A 0.00286658 0.978741 540.51 1.5E-119 0.362727 LOW NONE N/A lost rs115689904 0.928129986712 549.746 0.912536951824 -0.392001 0.724242169447 rs6938647 25580.4 0.00056849341761 LPA 0.0000 0.0000 0.0001 0.5648 biochemistry_LipoproteinA_v2 6:161020631:C:T 6 161020631 T C 0.00038011 0.871886 34.3968 4.5E-09 -0.269611 22.3 LPA missense lost 6:160952816:T:C 1.06236709228 1764.48 0.020709800281 -0.292071 0.0324438505305 rs4708876 10640.4 0.00022737322521 LPA 0.0004 0.0000 0.0003 0.0000 biochemistry_LipoproteinA_v2 6:161022107:C:T 6 161022107 T C 0.00807136 0.957589 650.015 2.2E-143 -0.252391 22.9 LPA missense won rs143368848 0.208304436379 831.437 0.162851795401 0.198712 192.077365098 rs12210186 15415.9 0.000207273609 LPA 0.0038 0.0054 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161134124:A:G 6 161134124 G A 0.000577048 0.955272 62.3362 2.9E-15 -0.268847 23.3 PLG missense lost 6:161007759:C:G 1.1909638576 307.112 0.241736438889 -0.357634 0.519762146795 rs6938647 25580.4 0.00191338006084 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161137790:G:A 6 161137790 A G 0.00310943 0.948663 286.804 2.5E-64 -0.261919 27.6 PLG missense lost rs150415123 0.66321188376 10503.2 0.018109892329 0.3454 9.88195960292 rs56393506 69878.1 0.00026138158929 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161139415:G:A 6 161139415 A G 3.15592e-05 0.726072 67.185 2.5E-16 1.55922 24.4 PLG missense lost rs143474459 0.448198286703 391.002 0.077012910144 -1.18749 7.33969449841 6:161017363:G:A 12725.2 0.00040211478784 PLG 0.0010 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161152807:G:A 6 161152807 A G 0.00272683 0.948208 116.598 3.5E-27 -0.172278 23.5 PLG missense lost rs111232411 0.885416846298 447.43 0.230735161801 0.210798 0.406346784547 6:161010118:A:G 82110.4 0.000187607809 PLG 0.0001 0.0762 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:161152819:C:T 6 161152819 T C 0.0024034 0.943976 171.751 3.1E-39 0.225329 23.3 PLG missense lost rs115630860 0.990509892042 176.721 0.962653360201 -0.226821 0.00388552504231 rs6938647 25580.4 0.00050142853476 PLG 0.0001 0.1405 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161152858:C:T 6 161152858 T C 0.000178146 0.713054 126.102 2.9E-29 0.849019 21.3 PLG missense lost rs143026639 0.434045430637 873.625 0.062651591809 -0.663855 14.6786440464 rs56393506 69878.1 0.0003912484 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161157972:G:A 6 161157972 A G 0.000748994 0.919054 76.8884 1.8E-18 -0.283352 23.0 PLG missense lost rs144647892 0.931844568008 3792.13 0.018893877025 0.325752 0.0924687099445 rs6938647 25580.4 0.00220677276169 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161160188:A:T 6 161160188 T A 7.83189e-05 0.905613 39.615 3.1E-10 0.66191 21.9 PLG missense lost rs374071816 1.06625347845 51558.7 0.00081925323076 -0.755994 0.0420896299541 6:161010118:A:G 82110.4 0.00089489525904 PLG 0.0000 0.0000 0.0001 0.0000 biochemistry_LipoproteinA_v2 6:161160219:T:C 6 161160219 C T 0.000348708 0.855891 257.032 7.6E-58 0.788357 23.4 PLG missense lost rs544960402 0.884595201391 506.606 0.448808884624 -0.870507 0.909064210559 6:161010118:A:G 82110.4 0.00234985471009 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161162369:T:A 6 161162369 A T 0.00170059 0.94914 220.816 6.0E-50 -0.331652 23.3 PLG missense lost rs181548067 0.958681140218 268.497 0.788433891844 0.353256 0.0962457990421 rs56393506 69878.1 0.00014622371929 PLG 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161470544:T:G 6 161470544 G T 0.00016421 0.723185 56.2509 6.4E-14 0.626363 22.4 MAP3K4 missense lost rs568310921 1.36439991523 101.658 0.7549698321 -0.81781 1.58904898422 rs56393506 69878.1 0.00045275753961 MAP3K4 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161470613:G:A 6 161470613 A G 2.54261e-05 0.899574 34.6923 3.9E-09 0.867739 21.1 MAP3K4 missense lost rs12525459 0.245003263889 2026.89 0.00419348200041 -0.480094 8.84817315083 6:160489092_TGG_T 3516.43 0.00016658032356 MAP3K4 0.0004 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161527612:G:C 6 161527612 C G 0.000110378 0.847837 160.084 1.1E-36 1.12823 24.3 MAP3K4 missense lost 6:161075802_GAAATA_G 0.955914209524 4551.88 0.033618322609 -1.06917 0.079546406409 6:161010118:A:G 82110.4 0.00118564526224 MAP3K4 0.0001 0.0000 0.0029 0.0000 biochemistry_LipoproteinA_v2 6:161532946:C:T 6 161532946 T C 0.00103474 0.875793 36.102 1.9E-09 -0.157611 25.0 MAP3K4 missense lost rs185162879 0.474500675374 273.791 0.062567518225 0.365639 3.49541322092 rs56393506 69878.1 0.00010309762369 MAP3K4 0.0000 0.0000 0.0000 0.0000 biochemistry_LipoproteinA_v2 6:161557649:A:G 6 161557649 G A 0.00020835 0.862952 261.055 1.0E-58 1.00686 21.7 AGPAT4 missense lost rs769334247 0.598577424625 312.402 0.500194075536 -1.02171 13.3716842702 6:161010118:A:G 82110.4 0.00113998068496 AGPAT4 0.0000 0.0000 0.0003 0.0000 biochemistry_LipoproteinA_v2 6:161575336:T:C 6 161575336 C T 2.48359e-05 0.570182 46.0099 1.2E-11 1.74016 24.7 AGPAT4 missense lost rs546400507 0.179428753271 312.319 0.026432906724 -0.969245 15.2867031105 6:160828142:T:C 6641.73 0.00065042851225 AGPAT4 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Phosphate_v2 12:111885310:G:A 12 111885310 A G 0.00199675 0.885884 49.6143 1.9E-12 0.172845 32 SH2B3 missense lost rs570074821 0.967461218085 50.7059 0.946633648401 -0.169475 0.0133506673405 rs570074821 50.7059 0.946633648401 SH2B3 0.0004 0.0000 0.0012 0.0000 biochemistry_Phosphate_v2 1:21887635:A:G 1 21887635 G A 4.3846e-05 0.8695 95.3753 1.6E-22 1.63503 26.4 ALPL missense won rs55722102 0.00110667136445 585.59 0.00018024405025 -0.0674439 89.1352117604 rs55722102 585.59 0.00018024405025 ALPL 0.0509 0.0000 0.0000 0.0000 biochemistry_Phosphate_v2 1:21889705:A:C 1 21889705 C A 0.000445222 0.902849 162.983 2.5E-37 0.675591 20.7 ALPL missense won rs56414407 0.00224036769443 831.546 0.000439112025 -0.0788312 147.91934879 rs10799700 1072.61 0.00029634245316 ALPL 0.0003 0.0000 0.0234 0.0000 biochemistry_Phosphate_v2 1:21889706:C:A 1 21889706 A C 0.000445222 0.902849 162.983 2.5E-37 0.675591 23.3 ALPL missense lost 1:21889705:A:C 1.0 162.983 1.0 0.675591 0.0 rs10799700 1072.61 0.00029634245316 ALPL 0.0000 0.0000 0.0072 0.0000 biochemistry_Phosphate_v2 1:21890587:G:A 1 21890587 A G 0.000422177 0.723251 42.1978 8.2E-11 0.404796 24.7 ALPL missense won rs71569834 0.0137564781715 153.37 0.00378491957089 0.0630456 32.8797008206 rs55722102 585.59 0.00097205521284 ALPL 0.0440 0.0000 0.0001 0.0000 biochemistry_Phosphate_v2 1:21890636:T:C 1 21890636 C T 0.000313836 0.805878 54.7855 1.3E-13 0.492049 23.6 ALPL missense won rs183888546 0.0175529712873 88.9748 0.010808097444 -0.0568636 41.230346539 rs12132412 1943.75 0.00035098898409 ALPL 0.0077 0.0000 0.0004 0.0000 biochemistry_Phosphate_v2 1:21900176:A:C 1 21900176 C A 0.000196498 0.921008 166.302 4.8E-38 0.976458 27.0 ALPL missense won rs12132412 0.00324576509101 1943.75 0.00027769889449 -0.107038 147.892789679 rs12132412 1943.75 0.00027769889449 ALPL 0.0027 0.0008 0.0000 0.0000 biochemistry_Phosphate_v2 1:21900186:C:A 1 21900186 A C 0.000141348 0.848582 61.9955 3.4E-15 0.728044 45 ALPL stop_gained won rs1067237 0.000767092528641 146.689 0.00032419803025 -0.0261431 58.6089475749 rs1067237 146.689 0.00032419803025 ALPL 0.0011 0.0017 0.0003 0.0000 biochemistry_Phosphate_v2 1:21900272:GCTT:G 1 21900272 G GCTT 3.89116e-05 0.829438 30.9827 2.6E-08 1.02548 22.6 ALPL inframe_deletion lost rs113298409 0.000896779041262 185.997 0.00014938217284 -0.0417523 29.1548520842 rs113298409 185.997 0.00014938217284 N/A N/A N/A N/A N/A biochemistry_Phosphate_v2 1:21902399:C:T 1 21902399 T C 0.000123075 0.828785 65.0887 7.2E-16 0.832589 28.8 ALPL missense won 1:21759127_AG_A 0.00137528164055 282.773 0.00031656238084 -0.048887 60.3506137678 1:21759127_AG_A 282.773 0.00031656238084 ALPL 0.0000 0.0000 0.0003 0.0000 biochemistry_Phosphate_v2 2:158152917:T:C 2 158152917 C T 0.00372857 0.910586 103.746 2.3E-24 0.181651 24.9 GALNT5 missense won rs77149268 0.0205854688675 139.769 0.015279926544 -0.0403968 76.1114610029 rs77149268 139.769 0.015279926544 GALNT5 0.0000 0.0000 0.0000 0.0000 biochemistry_Phosphate_v2 2:234959642:C:T 2 234959642 T C 0.00851023 0.96019 109.561 1.2E-25 -0.120803 22.0 SPP2 missense won N/A N/A N/A N/A N/A N/A rs147703120 72.3032 0.485038423809 SPP2 0.0030 0.0739 0.0000 0.0000 biochemistry_Phosphate_v2 3:122000982:G:A 3 122000982 A G 0.00158309 0.952918 57.0234 4.3E-14 0.20181 23.5 CASR missense won rs7618747 0.00228361032553 66.9051 0.00194632733584 0.0176253 51.7036493327 rs73186030 615.469 0.00015734190096 CASR 0.0001 0.0005 0.0000 0.0000 biochemistry_Phosphate_v2 5:14678932:A:G 5 14678932 G A 0.00285767 0.918552 30.5155 3.3E-08 -0.115889 LOW NONE N/A lost rs140791645 0.85473438916 34.4531 0.757047907225 0.122822 0.173860912894 5:14984166:C:T 118.922 0.00013787691241 OTULIN 0.0000 0.0000 0.6150 0.0000 biochemistry_Phosphate_v2 5:14751305:C:T 5 14751305 T C 0.00706783 0.89517 95.3303 1.6E-22 0.131514 20.1 ANKH missense won N/A N/A N/A N/A N/A N/A 5:14755919:C:T 90.1041 0.934443155556 ANKH 0.0002 0.0000 0.0000 0.0000 biochemistry_Phosphate_v2 5:176734657:C:T 5 176734657 T C 0.00679801 0.962303 33.9529 5.6E-09 -0.076037 22.3 MXD3 missense lost 5:176813433:C:T 0.670507845222 38.4938 0.591411755089 -0.106684 1.1142315277 rs10051765 542.25 0.011027310121 MXD3 0.0040 0.0025 0.0001 0.0000 biochemistry_Phosphate_v2 5:176813433:C:T 5 176813433 T C 0.0043098 0.934389 38.4938 5.5E-10 -0.106684 28.6 SLC34A1 missense lost rs10051765 0.109202101357 542.25 0.00775215094369 0.0519533 17.2562807725 rs10051765 542.25 0.00775215094369 SLC34A1 0.0333 0.0031 0.0001 0.0000 biochemistry_Phosphate_v2 6:33261007:G:A 6 33261007 A G 0.00145679 0.952521 53.3393 2.8E-13 -0.203089 22.9 RGL2 missense lost rs191209235 0.887115789374 75.4794 0.626901316441 0.265536 0.180249551748 rs60447213 2213.45 0.014493511321 RGL2 0.0073 0.0000 0.0211 0.0000 biochemistry_Phosphate_v2 6:33652626:G:A 6 33652626 A G 0.00315704 0.955411 101.95 5.7E-24 -0.190318 23.6 ITPR3 missense lost rs73743304 0.79232618467 1554.74 0.051955731844 0.182497 1.23074679544 rs60447213 2213.45 0.033511329721 ITPR3 0.0211 0.0000 0.0014 0.0000 biochemistry_Phosphate_v2 6:132181644:C:A 6 132181644 A C 0.000172635 0.940584 51.071 8.9E-13 -0.586217 33 ENPP1 missense won rs4897537 0.00109750241211 335.266 0.00016718231401 -0.04022 47.7432317451 rs767386057 399.551 0.00010174353424 ENPP1 0.0000 0.0000 0.0000 0.0000 biochemistry_Phosphate_v2 6:132193216:A:G 6 132193216 G A 0.000159454 0.663786 43.6838 3.9E-11 -0.662737 25.0 ENPP1 missense won rs13209786 0.000255556161105 47.8158 0.00023347228804 0.0173475 42.2982943755 rs13209786 47.8158 0.00023347228804 ENPP1 0.0000 0.0000 0.0004 0.0000 biochemistry_Phosphate_v2 6:132206135:T:A 6 132206135 A T 8.95393e-05 0.96409 31.5345 2.0E-08 -0.634377 24.0 ENPP1 missense lost rs449441 0.0022070959707 613.874 0.00011337777441 0.0536549 28.6411344457 rs449441 613.874 0.00011337777441 ENPP1 0.0000 0.0000 0.0003 0.0000 biochemistry_Phosphate_v2 9:140127380:G:A 9 140127380 A G 0.000497133 0.860092 55.6182 8.8E-14 -0.389098 24.7 SLC34A3 splice_donor won N/A N/A N/A N/A N/A N/A 9:140130606:A:T 52.8438 0.00232524555264 SLC34A3 0.0003 0.0005 0.2399 0.9081 biochemistry_Phosphate_v2 9:140127675:C:T 9 140127675 T C 0.00128881 0.640597 41.0768 1.5E-10 -0.240954 21.8 SLC34A3 missense lost 9:140248386:G:A 0.631908407732 45.5764 0.569522280889 -0.246611 1.72748775841 9:140248386:G:A 45.5764 0.569522280889 SLC34A3 0.0026 0.0004 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_SHBG_v2 10:64913602:A:G 10 64913602 G A 0.00346176 0.974674 59.8849 1.0E-14 -0.11914 28.3 NRBF2 missense lost rs545891513 0.885312966935 65.8307 0.805351887396 0.116621 0.209090764513 10:65126832:T:C 4644.18 0.00319308625476 NRBF2 0.0001 0.0000 0.0016 0.0000 biochemistry_SHBG_v2 11:14865399:C:T 11 14865399 T C 0.00106755 0.906863 42.3319 7.7E-11 0.204876 35 PDE3B stop_gained won 11:13248730:C:T 0.000293481641191 45.296 0.00027427665769 -0.0134993 40.8939221806 11:13248730:C:T 45.296 0.00027427665769 PDE3B 0.1111 0.0139 0.0003 0.0000 biochemistry_SHBG_v2 12:21690094:A:G 12 21690094 G A 0.000604759 0.933332 30.4874 3.4E-08 0.240553 26.1 GYS2 missense lost rs528314686 0.684779102547 31.8261 0.655975265929 -0.305064 0.907045466669 rs1871395 795.463 0.00010519579225 GYS2 0.0393 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 12:100926308:T:C 12 100926308 C T 0.00628883 0.95263 651.32 1.2E-143 -0.305623 25.9 NR1H4 missense won N/A N/A N/A N/A N/A N/A rs184757056 418.872 0.6224421025 NR1H4 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 12:112184086:G:A 12 112184086 A G 0.00203434 0.911388 31.5803 1.9E-08 0.125523 28.2 ACAD10 missense lost rs562602991 0.186267866099 32.7689 0.179511521344 -0.139881 10.2033626189 rs11830764 524.347 0.00578387628324 ACAD10 0.0001 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 14:94847386:G:A 14 94847386 A G 0.00425521 0.970109 131.564 1.9E-30 0.172942 23.1 SERPINA1 missense won rs61980636 0.0350195310721 281.683 0.016356363664 -0.0414386 86.9308352435 14:94795492:A:G 287.233 0.015977212801 SERPINA1 0.0004 0.0000 0.0301 0.0000 biochemistry_SHBG_v2 14:100795821:C:T 14 100795821 T C 0.00763075 0.964513 34.589 4.1E-09 0.0611963 25.5 SLC25A47 missense lost rs138504783 1.00004234964 34.8009 0.993953168784 -0.0601742 1.55084419322e-08 14:100795139:G:T 164.111 0.00759608118025 SLC25A47 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:6978411:C:T 17 6978411 T C 0.000482031 0.570516 749.915 4.2E-165 -1.56647 23.2 CLEC10A missense lost rs551720181 0.761569047971 3454.46 0.165325999609 2.65111 12.1565549167 rs858519 15722.8 0.00010936139776 CLEC10A 0.0001 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7005464:C:T 17 7005464 T C 0.000122219 0.534404 47.9728 4.3E-12 -0.783571 22.0 ASGR2 missense lost rs575551804 0.577386615875 2775.15 0.00998102900601 0.750764 2.76646714548 17:7534678:C:T 15522.4 0.00062512500625 ASGR2 0.0009 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7188423:G:A 17 7188423 A G 0.00189335 0.892294 85.9835 1.8E-20 0.211569 26.9 SLC2A4 missense lost 17:7533461:T:C 0.945078871694 1592.86 0.051015901689 0.572752 0.0666827339243 rs858519 15722.8 0.00023202296329 SLC2A4 0.0137 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7188459:C:T 17 7188459 T C 0.00504731 0.905756 40.1481 2.4E-10 -0.0847444 22.7 SLC2A4 missense lost 17:7318396:C:T 0.974524898874 2993.16 0.013071577561 0.154758 0.00659815167143 rs858519 15722.8 0.00176628553984 SLC2A4 0.0002 0.0000 0.0042 0.0028 biochemistry_SHBG_v2 17:7222374:G:A 17 7222374 A G 0.00379815 0.852734 78.2836 8.9E-19 0.141518 23.8 NEURL4 missense lost 17:7320870:G:A 0.702171281589 226.957 0.242197842496 0.225 2.05557546444 rs858519 15722.8 0.00142321335025 RP11-542C16.2 0.0000 0.0000 0.0005 0.0000 biochemistry_SHBG_v2 17:7287852:G:A 17 7287852 A G 0.000286653 0.589722 92.711 6.1E-22 0.731196 29.2 TNK1 missense lost 17:7533461:T:C 0.424588278223 1592.86 0.024712783209 0.572752 11.2532150645 17:7533423:G:A 15681.9 0.00031584753841 TNK1 0.0000 0.0013 0.0005 0.0000 biochemistry_SHBG_v2 17:7287938:GC:G 17 7287938 G GC 0.000283418 0.897905 36.5004 1.5E-09 -0.362046 26.4 TNK1 frameshift lost 17:7493899_AACT_A 1.36655467408 440.493 0.113236288036 0.398016 1.04245454408 rs858519 15722.8 0.00026913714916 N/A N/A N/A N/A N/A biochemistry_SHBG_v2 17:7287973:C:T 17 7287973 T C 0.000424759 0.82658 41.3785 1.3E-10 -0.327114 23.5 TNK1 missense lost rs11078696 0.383088129303 10657.0 0.00148743662929 -0.254429 6.00840060186 rs858519 15722.8 0.00039624485481 TNK1 0.0081 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7307391:C:G 17 7307391 G C 0.00542895 0.938694 126.868 2.0E-29 -0.147944 20.6 TMEM256 missense lost rs11653815 1.00105448573 7933.61 0.016008069529 -0.217269 3.52488238447e-05 rs858519 15722.8 0.0037859409 TMEM256 0.0001 0.0000 0.0260 0.0000 biochemistry_SHBG_v2 17:7323775:C:G 17 7323775 G C 4.26295e-05 0.843868 104.048 2.0E-24 -1.60269 20.2 SPEM1 missense lost 17:7536524:GA:G 0.964747600884 1728.65 0.058068468676 -1.49384 0.0329085910066 17:7559037:C:T 9587.67 0.00013881316761 SPEM1 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7324311:C:T 17 7324311 T C 9.42965e-05 0.504876 426.674 8.6E-95 -2.84945 22.0 SPEM1 missense won rs534003441 0.216643685348 3107.24 0.029748660484 1.35973 121.919416925 17:7534678:C:T 15522.4 0.00552080206441 SPEM1 0.0325 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7330298:C:T 17 7330298 T C 3.12116e-05 0.734258 66.5188 3.5E-16 -1.42552 22.3 C17orf74 missense lost 17:7536587:G:A 0.931543192379 178.62 0.346910398081 -1.48439 0.080719732698 rs779544949 11502.5 0.00010099044036 C17orf74 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7339494:ATCCGTTCCCTTTTTTTAGGTC:A 17 7339494 A ATCCGTTCCCTTTTTTTAGGTC 0.00882931 0.8814 600.415 1.4E-132 -0.258971 27.8 TMEM102 splice_acceptor lost 17:7339486:C:G 1.0 600.415 1.0 -0.258971 0.0 rs858519 15722.8 0.00500786921569 N/A N/A N/A N/A N/A biochemistry_SHBG_v2 17:7340400:G:T 17 7340400 T G 0.000446034 0.667632 31.354 2.2E-08 -0.303719 23.9 TMEM102 missense lost rs187417669 0.385515247043 131.656 0.091810818009 0.208528 4.50612678154 rs858519 15722.8 0.00018511779364 TMEM102 0.0298 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7348697:T:C 17 7348697 C T 0.000446983 0.598297 35.8448 2.1E-09 0.341167 29.3 CHRNB1 missense lost rs549158250 0.37560044035 145.607 0.092463430084 -0.235777 5.37225539226 rs858519 15722.8 0.00016391936961 CHRNB1 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7490531:C:T 17 7490531 T C 0.00123177 0.599857 89.0437 3.9E-21 0.324471 24.3 MPDU1 missense lost 17:7533423:G:A 0.443950353577 15681.9 0.00252080309776 0.276353 9.91576063548 rs858519 15722.8 0.000691795204 MPDU1 0.0044 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7495219:T:C 17 7495219 C T 0.00305571 0.96246 133.27 7.9E-31 -0.2022 22.4 FXR2 missense lost rs11078694 0.994165913024 12681.0 0.010448110656 0.25494 0.00113733352687 rs858519 15722.8 0.00380600157184 FXR2 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7496382:C:T 17 7496382 T C 0.00462581 0.825619 250.522 2.0E-56 -0.245276 24.5 FXR2 missense lost 17:7485785:C:T 1.01069644126 264.238 0.958233463236 -0.241955 0.00712772703331 rs858519 15722.8 0.00517201173889 FXR2 0.0000 0.0000 0.0002 0.0000 biochemistry_SHBG_v2 17:7534044:A:AT 17 7534044 AT A 5.04472e-05 0.744279 37.3923 9.7E-10 -0.966147 29.1 SHBG frameshift lost 17:7399243:CCTTT:C 0.111813023011 7611.31 0.00054930703129 -0.433278 16.5664317596 17:7533901:C:T 8172.02 0.00023193767025 N/A N/A N/A N/A N/A biochemistry_SHBG_v2 17:7534084:T:C 17 7534084 C T 0.000171763 0.757395 134.553 4.1E-31 -0.931137 22.6 SHBG missense lost rs12944954 0.333303610156 8965.92 0.00500194075536 0.586062 24.0385063359 rs858519 15722.8 0.000195608196 SHBG 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7534101:G:A 17 7534101 A G 2.24605e-05 0.888599 38.1818 6.4E-10 -1.35431 26.2 SHBG missense won rs116933867 0.00939166767809 529.006 0.00067785767449 0.139999 31.1399471882 rs1794287 1896.87 0.00010382591025 SHBG 0.0007 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7534678:C:T 17 7534678 T C 0.00690955 0.973007 15522.4 1.5E-3373 -1.42897 23.4 SHBG missense won rs858519 0.00853038626356 15722.8 0.00842165948416 -0.237197 12787.5115392 rs858519 15722.8 0.00842165948416 SHBG 0.0000 0.0000 0.0356 0.0012 biochemistry_SHBG_v2 17:7535009:G:T 17 7535009 T G 1.79516e-05 0.906609 47.8043 4.7E-12 -1.59734 34 SHBG stop_gained won rs12944649 0.0023044714848 1098.69 0.00010026817956 0.0774994 43.3247813077 rs12944649 1098.69 0.00010026817956 SHBG 0.0208 0.0000 0.0068 0.0000 biochemistry_SHBG_v2 17:7536524:GA:G 17 7536524 G GA 0.000938096 0.714946 1728.65 8.2E-378 -1.49384 30 SHBG frameshift won 17:7536460:G:T 0.0157276626272 4545.01 0.00598186230625 -0.216402 1322.25770644 rs858519 15722.8 0.00072472408849 N/A N/A N/A N/A N/A biochemistry_SHBG_v2 17:7536587:G:A 17 7536587 A G 7.79648e-05 0.845576 178.62 9.7E-41 -1.48439 25.6 SHBG missense won rs572908739 0.291726376799 195.438 0.266622486025 1.29739 37.7767673154 rs858518 13533.5 0.00010669237264 SHBG 0.0001 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7605071:C:T 17 7605071 T C 0.000582728 0.685731 31.6657 1.8E-08 0.251672 26.8 WRAP53 missense lost 17:7454279:G:A 0.67035592454 96.887 0.219093269476 0.279235 1.04023714518 rs858519 15722.8 0.00021090591076 WRAP53 0.0025 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7637938:A:G 17 7637938 G A 0.00714537 0.840864 91.8488 9.4E-22 0.120095 22.3 DNAH2 missense lost rs191963994 1.11469705393 649.098 0.157732094025 -0.244896 0.285903589371 rs858519 15722.8 0.00020948509696 DNAH2 0.0000 0.0000 0.1504 0.0000 biochemistry_SHBG_v2 17:7644167:T:C 17 7644167 C T 0.00296775 0.862124 129.015 6.7E-30 -0.206324 24.6 DNAH2 missense lost 17:7551450_CAA_C 0.983732140975 750.115 0.169195659556 0.267441 0.00860587994762 rs858519 15722.8 0.00270357361681 DNAH2 0.0012 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7674225:G:T 17 7674225 T G 6.28133e-05 0.903108 75.1179 4.4E-18 -1.08919 27.0 DNAH2 missense lost 17:7536524:GA:G 0.990478241648 1728.65 0.043040896369 -1.49384 0.00171077463953 17:7579472:G:C 8431.29 0.00014592156804 DNAH2 0.0025 0.0000 0.1025 0.0159 biochemistry_SHBG_v2 17:7674232:G:A 17 7674232 A G 0.000165209 0.621484 32.2337 1.4E-08 -0.55842 28.2 DNAH2 missense lost 17:7466276_TTTTC_T 0.522936003895 521.265 0.032337030625 0.402458 2.47070407291 17:7559037:C:T 9587.67 0.00033312090256 DNAH2 0.0000 0.0000 0.0443 0.0454 biochemistry_SHBG_v2 17:7721995:G:A 17 7721995 A G 0.00405463 0.546801 81.6478 1.6E-19 0.184262 22.3 DNAH2 missense lost rs9630723 0.214738470556 335.751 0.052220019289 -0.123178 23.5097346088 rs77294902 12736.5 0.00015161243161 DNAH2 0.0220 0.0013 0.0000 0.0000 biochemistry_SHBG_v2 17:7722251:C:T 17 7722251 T C 0.000466445 0.923214 57.2192 3.9E-14 -0.337675 28.3 DNAH2 missense lost rs535951411 1.10243496901 68.0285 0.927264998916 0.361737 0.142870860772 rs858519 15722.8 0.00037475926569 DNAH2 0.0352 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7751597:C:T 17 7751597 T C 3.77255e-05 0.600669 34.0848 5.3E-09 1.13928 26.3 KDM6B missense lost rs192233618 0.271162782915 348.857 0.026493747361 -0.582402 7.82917377447 rs78496430 1759.07 0.00027892006081 KDM6B 0.0006 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:7752007:G:A 17 7752007 A G 0.000514562 0.955236 41.5145 1.2E-10 -0.291389 24.5 KDM6B missense lost rs760650551 0.947140584251 44.0591 0.8924391961 0.299755 0.0297918355486 rs858519 15722.8 0.00046605037924 KDM6B 0.0005 0.0000 0.0011 0.0000 biochemistry_SHBG_v2 17:7760760:T:G 17 7760760 G T 3.79675e-05 0.615017 31.4652 2.0E-08 1.07136 22.7 LSMD1 missense lost 17:7751597:C:T 1.08325388048 34.0848 1.0 1.13928 0.0523649599468 rs78496430 1759.07 0.00029897522281 NAA38 0.0000 0.0000 0.0002 0.0000 biochemistry_SHBG_v2 17:7837525:C:T 17 7837525 T C 8.2449e-05 0.920134 89.5883 2.9E-21 -1.05012 31 CNTROB missense lost 17:7388716:G:C 0.978015091023 14013.3 0.006252539329 -1.31309 0.0109459751112 rs858519 15722.8 0.000103591684 CNTROB 0.0001 0.0000 0.0001 0.0000 biochemistry_SHBG_v2 17:7917252:T:C 17 7917252 C T 0.000813437 0.929636 160.832 7.4E-37 0.42522 21.6 GUCY2D missense lost 17:7533461:T:C 1.03783451111 1592.86 0.104790753796 0.572752 0.0564920372807 rs858519 15722.8 0.00045025020481 GUCY2D 0.0011 0.0000 0.0018 0.0000 biochemistry_SHBG_v2 17:7980420:G:A 17 7980420 A G 0.000124925 0.748834 87.018 1.1E-20 -0.917191 24.4 ALOX12B missense lost rs545206972 1.00683816691 15288.2 0.00573076252324 1.43176 0.00101378860148 17:7534678:C:T 15522.4 0.00544288342081 ALOX12B 0.0035 0.0000 0.0022 0.0000 biochemistry_SHBG_v2 17:8222332:C:T 17 8222332 T C 4.92916e-05 0.552616 35.6359 2.4E-09 -1.06169 31 ARHGEF15 missense lost 17:7810133:CCTGT:C 1.19264794687 232.418 0.182864851129 -1.78388 0.30217475127 17:7534678:C:T 15522.4 0.00137517855556 ARHGEF15 0.0558 0.0335 0.0000 0.0000 biochemistry_SHBG_v2 17:8396312:C:T 17 8396312 T C 1.61589e-05 0.532224 37.6246 8.6E-10 -1.95612 23.7 MYH10 missense lost rs572373055 0.047483184358 1077.94 0.00165736109449 1.53584 23.0138560993 17:7657078_CAACATGACGA_C 7839.96 0.00010013004225 MYH10 0.0003 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:38416827:G:A 17 38416827 A G 0.00730277 0.992005 51.49 7.2E-13 -0.0773317 23.4 WIPF2 missense lost rs113784243 1.00035990996 56.8624 0.905845194081 0.0809771 1.66714161148e-06 rs11867902 119.684 0.2467804329 WIPF2 0.0003 0.0588 0.0000 0.0000 biochemistry_SHBG_v2 17:42082405:C:A 17 42082405 A C 0.00411358 0.945316 56.3287 6.1E-14 0.11776 20.4 NAGS missense won N/A N/A N/A N/A N/A N/A rs150447622 42.8617 0.00044595725329 NAGS 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 17:78896587:G:A 17 78896587 A G 0.00678219 0.911998 39.7102 2.9E-10 0.0725605 22.1 RPTOR missense won rs4969273 0.000158176414528 41.2684 0.00015220403641 0.0138141 38.7176251002 rs3736072 46.2696 0.00010499076225 RPTOR 0.0000 0.0000 0.0000 0.0002 biochemistry_SHBG_v2 19:3382176:C:T 19 3382176 T C 0.00164205 0.909897 43.0166 5.4E-11 -0.154484 26.0 NFIC missense won rs6510738 0.000842172130639 43.7103 0.000828806521 -0.0126427 40.5561265293 rs60018147 114.835 0.00020390983209 NFIC 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 19:46376312:C:T 19 46376312 T C 0.00047488 0.931902 55.0988 1.1E-13 0.34726 27.9 FOXA3 missense lost rs571484622 0.749660729692 58.9025 0.701250483649 -0.322819 0.991873282568 rs10422060 106.182 0.00042415814401 FOXA3 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 1:27226912:C:A 1 27226912 A C 0.000561907 0.875751 49.7924 1.7E-12 -0.290304 35 GPATCH3 stop_gained lost rs79598313 0.421135896325 1017.42 0.020610334969 0.202094 6.1362268635 1:27021913:G:C 1034.47 0.0186677569 GPATCH3 0.0000 0.0000 0.0002 0.0000 biochemistry_SHBG_v2 1:63299729:TTG:T 1 63299729 T TTG 0.00250995 0.933372 34.6848 3.9E-09 0.120763 35 ATG4C frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_SHBG_v2 1:214170089:C:T 1 214170089 T C 0.000111537 0.911306 38.8359 4.6E-10 0.56467 32 PROX1 missense won 1:214163973_CAG_C 0.000488196889187 106.45 0.00017810770849 0.0196058 37.1386873219 rs35146556 109.452 0.00014086841344 PROX1 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 20:43042354:C:T 20 43042354 T C 0.000174879 0.965032 306.018 1.6E-68 -1.30878 26.8 HNF4A missense won rs6031601 0.000355470845646 414.645 0.00026234604841 -0.0416591 294.587493829 20:43058096:C:G 438.572 0.00024770038225 HNF4A 0.0000 0.0050 0.0000 0.0000 biochemistry_SHBG_v2 20:43048414:G:A 20 43048414 A G 0.000741715 0.914917 62.8365 2.2E-15 -0.299197 27.4 HNF4A missense won 20:43058096:C:G 0.00657590757759 438.572 0.00094216460809 0.0426511 53.0586358869 20:43058096:C:G 438.572 0.00094216460809 HNF4A 0.0013 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 2:27594142:A:C 2 27594142 C A 0.00833423 0.934706 34.3294 4.7E-09 0.0609735 29.4 SNX17 missense lost 2:27455281:C:T 0.999448050721 219.349 0.156419459001 0.0658473 2.61531763358e-06 2:27730940:T:C 2201.17 0.00499008024025 SNX17 0.0000 0.0005 0.0172 0.0001 biochemistry_SHBG_v2 2:27726437:A:C 2 27726437 C A 0.00378651 0.950472 49.3253 2.2E-12 -0.10046 22.6 GCKR missense lost rs191384615 1.00127233229 50.4056 0.979812921025 0.0996101 1.99496229585e-05 rs141306206 1329.25 0.00439148758489 GCKR 0.0000 0.0000 0.0001 0.0243 biochemistry_SHBG_v2 2:28113157:A:G 2 28113157 G A 0.00496589 0.946225 45.1454 1.8E-11 -0.0933147 22.2 RBKS missense lost rs111895996 1.0171717966 50.6528 0.906576292449 0.106826 0.00329974182648 2:27730940:T:C 2201.17 0.00635545378521 RBKS 0.0003 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 3:114069607:C:T 3 114069607 T C 0.00574602 0.913493 36.2812 1.7E-09 0.0749929 24.0 ZBTB20 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ZBTB20 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 3:126070736:G:A 3 126070736 A G 0.000232556 0.92825 33.1252 8.6E-09 0.338532 25.4 KLF15 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A KLF15 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 4:2828992:C:T 4 2828992 T C 0.00831559 0.946048 35.344 2.8E-09 0.0640052 20.6 SH3BP2 missense lost rs114524202 0.930071323064 281.561 0.116750689344 -0.152182 0.0447884014105 rs13108218 854.197 0.00357546594304 SH3BP2 0.0001 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 4:3445768:GCCCTGGATCCCTGTGC:G 4 3445768 G GCCCTGGATCCCTGTGC 0.00101006 0.914946 55.7685 8.2E-14 0.217087 25.3 HGFAC frameshift won 4:3444593:G:A 0.0248240165359 254.386 0.00544211617849 0.043086 39.5795309156 rs13108218 854.197 0.00011957203801 N/A N/A N/A N/A N/A biochemistry_SHBG_v2 4:110638764:A:G 4 110638764 G A 0.00169644 0.93174 66.9611 2.8E-16 0.202416 25.5 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs116481320 30.3126 0.013304930409 PLA2G12A 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 4:110638824:C:T 4 110638824 T C 0.00773323 0.943901 232.677 1.6E-52 0.171122 26.2 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs547113723 219.075 0.913058602681 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 5:102338739:C:G 5 102338739 G C 0.00942531 0.948169 35.9114 2.1E-09 -0.0610361 33 PAM missense won N/A N/A N/A N/A N/A N/A rs146640831 34.5861 0.00103307602225 PAM 0.1032 0.0109 0.0000 0.0000 biochemistry_SHBG_v2 5:131008584:C:T 5 131008584 T C 0.00343449 0.917733 41.3407 1.3E-10 0.108558 32 FNIP1 missense lost rs560025837 1.02545677603 45.7003 0.927632880769 -0.141987 0.00661376570801 rs6894249 61.8005 0.00124280221156 FNIP1 0.0006 0.0184 0.0000 0.0000 biochemistry_SHBG_v2 5:169015479:G:A 5 169015479 A G 0.00797051 0.950902 77.5205 1.3E-18 0.0971455 21.5 SPDL1 missense won N/A N/A N/A N/A N/A N/A rs182468878 53.3652 0.413077429521 SPDL1 0.0000 0.0000 0.0000 0.0000 biochemistry_SHBG_v2 7:2296552:A:G 7 2296552 G A 0.00377428 0.988495 30.3191 3.7E-08 0.0880852 24.4 SNX8 missense lost rs62442919 0.0151081925154 82.3594 0.00556180350625 0.0175973 23.3237989417 rs62442919 82.3594 0.00556180350625 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_SHBG_v2 9:88940359:C:T 9 88940359 T C 0.00565015 0.960914 42.8443 5.9E-11 0.0896599 31 ZCCHC6 missense lost rs117522510 1.12300166049 49.9099 0.964021567716 -0.095474 0.152791638026 rs7848649 115.158 0.000169702729 ZCCHC6 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_TotalBilirubin_v2 10:52573772:C:T 10 52573772 T C 0.00987688 0.962839 36.1916 1.8E-09 0.0521892 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs61848380 36.1742 0.00037455409156 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 12:20876168:C:T 12 20876168 T C 0.0071578 0.931822 49.619 1.9E-12 -0.069051 27.1 SLCO1C1 missense lost rs144146640 1.07401550603 169.696 0.314041435236 0.129618 0.0655525785962 rs77289848 4279.83 0.00015322478656 SLCO1C1 0.0000 0.0000 0.0002 0.0386 biochemistry_TotalBilirubin_v2 12:21008080:T:TAATTG 12 21008080 TAATTG T 0.0023111 0.855625 377.94 3.5E-84 0.380291 23.9 LST3 frameshift lost rs189206203 0.692526089935 383.487 0.682508951881 -0.341367 10.643939593 12:21344313_GA_G 1885.27 0.00047085094081 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 12:21015424:C:G 12 21015424 G C 0.000421499 0.863739 31.1527 2.4E-08 0.256504 24.2 LST3 missense lost rs149648124 1.01908828321 46.6374 0.680727303844 -0.264127 0.00281095460858 rs11045913 1791.47 0.00022656872484 SLCO1B3 0.0010 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 12:21032543:G:A 12 21032543 A G 0.000727099 0.862134 131.976 1.5E-30 0.387126 25.2 LST3 missense won rs67981690 0.144597774631 5401.69 0.00353286395641 -0.189704 50.6890112377 rs4149083 6074.83 0.00278063218489 SLCO1B3 0.0000 0.0000 0.0000 0.1169 biochemistry_TotalBilirubin_v2 12:21200143:T:G 12 21200143 G T 0.000357637 0.883466 85.1007 2.8E-20 0.432843 21.9 LST3 missense lost rs548489043 0.743562765581 109.028 0.580380377929 -0.509686 1.61359899933 rs4149083 6074.83 0.00112471024689 SLCO1B7 0.0002 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 12:21331930:G:A 12 21331930 A G 0.00027943 0.925301 31.1468 2.4E-08 0.324847 25.2 SLCO1B1 missense lost rs56148886 0.0657913666019 2723.66 0.00075236649849 -0.107583 17.2177894087 12:21385671_GAGAA_G 2770.9 0.00056120188609 SLCO1B1 0.0000 0.0000 0.0021 0.0305 biochemistry_TotalBilirubin_v2 12:21355598:G:A 12 21355598 A G 0.000109063 0.946685 38.3707 5.9E-10 0.449009 24.4 SLCO1B1 missense lost rs4149067 0.0519096047776 4884.74 0.00040776128761 -0.156094 22.8779933159 rs67981690 5401.69 0.00030076577476 SLCO1B1 0.0000 0.0000 0.0001 0.1928 biochemistry_TotalBilirubin_v2 12:21375289:C:T 12 21375289 T C 0.000587648 0.929363 134.694 3.9E-31 0.431745 42 SLCO1B1 stop_gained lost rs73079474 0.566675532875 2136.46 0.035726292196 -0.324105 8.23228842803 rs4149083 6074.83 0.00291755540736 SLCO1B1 0.0000 0.0000 0.0024 0.1176 biochemistry_TotalBilirubin_v2 12:21377774:G:A 12 21377774 A G 7.94928e-05 0.701206 31.0413 2.5E-08 0.678722 25.8 SLCO1B1 splice_donor lost rs548489043 0.532348404022 109.028 0.151564611969 -0.509686 2.26924973195 rs4149083 6074.83 0.00027018811876 SLCO1B1 0.0000 0.0000 0.0259 0.9859 biochemistry_TotalBilirubin_v2 12:21728874:C:T 12 21728874 T C 0.000315534 0.935851 37.7945 7.9E-10 0.322799 24.5 GYS2 missense lost rs372202274 0.964082971424 63.5672 0.573204952609 -0.3787 0.0124129753073 rs4149083 6074.83 0.00131903344225 GYS2 0.0000 0.0000 0.0006 0.0000 biochemistry_TotalBilirubin_v2 16:88782050:G:A 16 88782050 A G 0.0099661 0.908822 47.5072 5.5E-12 0.0632152 24.7 PIEZO1 missense won N/A N/A N/A N/A N/A N/A rs527468645 36.4958 0.615082569984 PIEZO1 0.0001 0.0000 0.0001 0.0000 biochemistry_TotalBilirubin_v2 16:88782205:G:C 16 88782205 C G 0.00143756 0.954236 70.8867 3.8E-17 0.198669 23.3 PIEZO1 missense won rs837756 0.00287185492547 124.468 0.00163557154084 0.0199513 63.4926836946 rs837756 124.468 0.00163557154084 PIEZO1 0.0331 0.0000 0.0001 0.0000 biochemistry_TotalBilirubin_v2 16:88786073:G:A 16 88786073 A G 3.23808e-05 0.839812 32.8435 1.0E-08 0.904451 32 PIEZO1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PIEZO1 0.0081 0.0000 0.0002 0.0000 biochemistry_TotalBilirubin_v2 16:88798288:C:G 16 88798288 G C 0.000191115 0.875973 59.928 9.8E-15 0.469955 25.8 PIEZO1 missense won N/A N/A N/A N/A N/A N/A 16:88737732_C_T 45.4127 0.7099579081 PIEZO1 0.0241 0.0000 0.0004 0.0000 biochemistry_TotalBilirubin_v2 16:88798919:G:T 16 88798919 T G 0.001426 0.936239 69.5062 7.6E-17 0.197756 22.4 PIEZO1 missense lost 16:88782205:G:C 1.00789106061 70.8867 0.988262644996 0.198669 0.00107776937567 rs837756 124.468 0.00169106000625 PIEZO1 0.0076 0.0000 0.0001 0.0000 biochemistry_TotalBilirubin_v2 19:40964064:G:A 19 40964064 A G 0.00676074 0.872551 65.3136 6.4E-16 0.0937765 32 BLVRB missense won N/A N/A N/A N/A N/A N/A 19:40948068:A:G 48.5745 0.643229664256 BLVRB 0.0000 0.0000 0.0546 0.0985 biochemistry_TotalBilirubin_v2 1:155264120:C:G 1 155264120 G C 3.24257e-05 0.811592 36.3314 1.7E-09 1.04917 27.1 PKLR missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PKLR 0.0003 0.0000 0.0024 0.0000 biochemistry_TotalBilirubin_v2 1:158583604:C:A 1 158583604 A C 0.000796983 0.972715 35.0513 3.2E-09 0.187148 27.8 SPTA1 missense won rs2022003 0.00253474202004 298.749 0.00029739347401 0.0328788 31.6107449751 1:158607935:T:G 320.562 0.00026360120164 SPTA1 0.0001 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:232135750:C:T 2 232135750 T C 0.000362542 0.972376 35.2252 2.9E-09 0.256167 29.5 ARMC9 missense lost rs769719963 0.992977116762 46.201 0.757079230609 -0.27929 0.000435866412353 rs1976391 121975.0 0.00022736719369 ARMC9 0.0000 0.0000 0.0044 0.0004 biochemistry_TotalBilirubin_v2 2:233656040:A:G 2 233656040 G A 0.00039661 0.865002 33.4838 7.2E-09 0.247783 22.5 GIGYF2 missense lost 2:234570282_TTTC_T 0.999859942828 61240.2 0.00054668518969 -0.459876 1.6421615164e-07 rs1976391 121975.0 0.00029074683169 GIGYF2 0.0341 0.0000 0.0020 0.0000 biochemistry_TotalBilirubin_v2 2:234181677:G:A 2 234181677 A G 0.00170561 0.782133 69.1976 8.9E-17 -0.171673 23.4 ATG16L1 missense lost rs4399719 0.939247234392 73488.8 0.00088440217321 -0.41537 0.0658667991999 rs1976391 121975.0 0.00049566788496 ATG16L1 0.0000 0.0000 0.0003 0.0000 biochemistry_TotalBilirubin_v2 2:234202986:C:T 2 234202986 T C 8.43942e-05 0.80841 34.6202 4.0E-09 0.479951 22.6 ATG16L1 missense lost rs112233788 0.733032664818 72621.8 0.00034945068096 -0.541356 0.716157917704 rs1976391 121975.0 0.00017129050884 ATG16L1 0.0009 0.0000 0.1214 0.0000 biochemistry_TotalBilirubin_v2 2:234227414:G:C 2 234227414 C G 0.000172174 0.875429 40.9946 1.5E-10 0.377585 25.2 SAG missense lost 2:234673309:C:T 0.980235737999 121086.0 0.00033186637584 0.569018 0.00404344727314 rs1976391 121975.0 0.00032215942144 SAG 0.0000 0.0002 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234229468:C:T 2 234229468 T C 0.00331821 0.910413 114.236 1.2E-26 -0.145601 25.9 SAG missense lost rs17862865 0.937009734951 62827.5 0.00170371643121 -0.385917 0.117031540892 rs1976391 121975.0 0.00084119721156 SAG 0.0003 0.0000 0.0093 0.0104 biochemistry_TotalBilirubin_v2 2:234231596:C:G 2 234231596 G C 0.000106095 0.704851 62.4322 2.8E-15 0.703214 25.7 SAG missense lost rs191296211 0.598284556145 707.758 0.052775413441 -0.590976 3.20323581671 rs1976391 121975.0 0.00012716170756 SAG 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234237186:C:T 2 234237186 T C 0.00021666 0.821143 50.7285 1.1E-12 0.390228 24.6 SAG missense lost rs535051221 0.951212395876 203.51 0.237106668096 -0.425327 0.0309459882167 rs1976391 121975.0 0.00034415444196 SAG 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234247384:A:G 2 234247384 G A 0.000200292 0.923488 31.7973 1.7E-08 0.306815 23.3 SAG missense lost rs112233788 1.04158868385 72621.8 0.00045605738025 -0.541356 0.0134706146783 rs1976391 121975.0 0.00022479904489 SAG 0.0000 0.0000 0.8451 0.5146 biochemistry_TotalBilirubin_v2 2:234357944:C:T 2 234357944 T C 0.00166241 0.969618 203.076 4.5E-46 -0.267336 26.9 DGKD missense lost rs542181527 1.00581401518 206.004 0.9915180625 0.26762 0.00171116220249 rs1976391 121975.0 0.00076292516521 DGKD 0.0001 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234358615:T:G 2 234358615 G T 0.0039589 0.979854 101.569 6.9E-24 -0.120596 LOW NONE N/A lost rs6741669 0.998395986428 72941.9 0.00139023088164 -0.414412 6.53831408853e-05 rs1976391 121975.0 0.00061618629361 DGKD 0.5808 0.0257 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234368445:C:G 2 234368445 G C 0.000606974 0.965881 30.8352 2.8E-08 -0.169226 26.0 DGKD missense lost 2:234649573_GT_G 0.999753667336 72678.8 0.00042416226304 -0.414305 4.67825921594e-07 rs1976391 121975.0 0.00028404720369 DGKD 0.0004 0.0000 0.0003 0.0000 biochemistry_TotalBilirubin_v2 2:234371365:C:T 2 234371365 T C 0.000170992 0.825777 64.058 1.2E-15 0.529691 24.3 DGKD missense lost rs773038058 1.07349294029 80.5076 0.854153033616 -0.610297 0.0834581065143 rs1976391 121975.0 0.00027047420521 DGKD 0.0000 0.0000 0.0004 0.0004 biochemistry_TotalBilirubin_v2 2:234377185:C:T 2 234377185 T C 0.000398309 0.762864 115.425 6.4E-27 0.457473 33 DGKD missense lost 2:234664586_ATC_A 0.534086526522 121083.0 0.00050912958321 -0.572402 8.36393229025 rs1976391 121975.0 0.00049483112704 DGKD 0.0000 0.0000 0.0000 0.0076 biochemistry_TotalBilirubin_v2 2:234394468:A:G 2 234394468 G A 0.000317553 0.854703 36.3978 1.6E-09 -0.283501 20.2 USP40 missense lost 2:234664586_ATC_A 0.486975365063 121083.0 0.000146385801 -0.572402 3.3232269036 rs1976391 121975.0 0.00014430976641 USP40 0.0001 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234398065:G:A 2 234398065 A G 0.000399263 0.903525 57.2217 3.9E-14 0.303462 23.6 USP40 missense lost rs539698867 0.996764653212 99.1011 0.575539201449 -0.295941 0.0001499843143 rs1976391 121975.0 0.00067001251716 USP40 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234405421:C:T 2 234405421 T C 0.000248434 0.83379 80.8769 2.4E-19 0.480805 29.2 USP40 missense lost rs192958236 0.803829924517 1415.15 0.045939492225 -0.453378 0.865275215406 rs1976391 121975.0 0.00046886540089 USP40 0.0001 0.0000 0.0000 0.0035 biochemistry_TotalBilirubin_v2 2:234432123:G:A 2 234432123 A G 0.000331493 0.908655 69.9265 6.2E-17 0.362886 23.5 USP40 missense lost rs112233788 0.869745634306 72621.8 0.000837465721 -0.541356 0.317644781543 rs1976391 121975.0 0.00046473011776 USP40 0.0000 0.0000 0.0062 0.0000 biochemistry_TotalBilirubin_v2 2:234460035:G:A 2 234460035 A G 0.000168932 0.818781 33.8003 6.1E-09 0.384574 31 USP40 missense lost rs929596 0.983009270805 94657.9 0.00035101146609 -0.528289 0.00246035526315 rs1976391 121975.0 0.00024936831396 USP40 0.0001 0.0000 0.0000 0.0077 biochemistry_TotalBilirubin_v2 2:234463169:C:A 2 234463169 A C 0.0010678 0.760536 77.6916 1.2E-18 -0.239871 29.8 USP40 missense lost 2:234668570:C:T 0.500720068547 121725.0 0.000319587129 0.57015 6.64174159715 rs1976391 121975.0 0.00031769141121 USP40 0.0055 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234465550:A:T 2 234465550 T A 0.000233366 0.830574 44.343 2.8E-11 -0.358004 24.0 USP40 missense lost 2:234669227:T:C 0.901054938954 68.6879 0.5816960361 -0.336858 0.114257066131 rs7576166 78312.4 0.000114854089 USP40 0.0000 0.0000 0.0003 0.0000 biochemistry_TotalBilirubin_v2 2:234545341:T:A 2 234545341 A T 0.00076283 0.865263 57.1907 4.0E-14 -0.208154 22.8 UGT1A10 missense lost 2:234580842:C:T 0.983491863823 107.956 0.521014006969 -0.213992 0.00392887850999 rs1976391 121975.0 0.00032962944249 UGT1A8 0.0000 0.0000 0.0028 0.0000 biochemistry_TotalBilirubin_v2 2:234545460:T:C 2 234545460 C T 9.81811e-05 0.784895 31.9998 1.5E-08 0.496596 22.8 UGT1A10 missense lost rs149780205 0.646935053091 5993.64 0.00345395991616 -0.409465 1.22525935695 rs1976391 121975.0 0.00013585767364 UGT1A8 0.0001 0.0000 0.0017 0.0000 biochemistry_TotalBilirubin_v2 2:234545792:G:A 2 234545792 A G 0.000843092 0.93278 189.938 3.3E-43 0.372158 35 UGT1A10 stop_gained lost 2:234674903_AGTGGCCCGGGCTCG_A 0.999253744929 100892.0 0.00188118243076 -0.535698 2.645382968e-05 rs1976391 121975.0 0.00158558461636 UGT1A8 0.0037 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234580842:C:T 2 234580842 T C 0.0015459 0.850006 107.956 2.7E-25 -0.213992 20.7 UGT1A8 missense lost rs528831440 0.929672462623 319.721 0.313910316729 0.236684 0.138397516266 rs1976391 121975.0 0.00058780547809 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234581127:T:G 2 234581127 G T 0.000706932 0.88596 38.401 5.8E-10 -0.191348 23.2 UGT1A8 missense lost 2:234649573_GT_G 0.994889459963 72678.8 0.00052566567076 -0.414305 0.000251378427482 rs1976391 121975.0 0.00026939969956 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234581154:A:AAT 2 234581154 AAT A 9.0105e-05 0.772213 53.9969 2.0E-13 0.65479 23.0 UGT1A8 frameshift lost 2:234664586_ATC_A 0.451331330862 121083.0 0.000201270969 -0.572402 5.81586458456 rs1976391 121975.0 0.00019650712761 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 2:234581395:T:C 2 234581395 C T 0.000134254 0.678817 51.3134 7.9E-13 0.56892 25.3 UGT1A8 missense lost rs542800224 1.10349388564 807.334 0.070137047556 -0.685479 0.130722996417 rs1976391 121975.0 0.00015820859961 UGT1A9 0.0000 0.0000 0.0000 0.0007 biochemistry_TotalBilirubin_v2 2:234591084:CT:C 2 234591084 C CT 0.000173173 0.690781 46.2092 1.1E-11 -0.456471 24.0 UGT1A7 frameshift lost 2:234591443:G:C 0.897955999478 62.8527 0.660175750144 -0.414495 0.126853209912 rs7592624 45891.9 0.00017696714841 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 2:234591185:T:C 2 234591185 C T 0.000568231 0.882847 157.239 4.5E-36 0.429552 23.2 UGT1A7 missense lost 2:234604081_CTTT_C 0.912631916441 88224.4 0.00162654923025 -0.5466 0.313928848353 rs1976391 121975.0 0.00113394501081 UGT1A9 0.0061 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234591411:C:A 2 234591411 A C 0.00508152 0.910772 671.527 4.7E-148 -0.292336 22.5 UGT1A7 missense lost rs757254535 0.951258699148 10526.7 0.0606833956 0.313447 0.408865649709 rs1976391 121975.0 0.00185877388225 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234602173:C:G 2 234602173 G C 0.000130985 0.843296 37.9308 7.3E-10 0.456011 21.3 UGT1A6 missense lost rs929596 0.868769070329 94657.9 0.00034812842724 -0.528289 0.174990785986 rs1976391 121975.0 0.00025723348225 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234628292:A:C 2 234628292 C A 0.00390217 0.952625 363.093 6.0E-81 -0.241518 21.6 UGT1A4 missense lost 2:234644514_CAG_C 0.803615769069 4600.37 0.063426911409 0.231331 3.8935885184 rs1976391 121975.0 0.00166228259521 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234628308:G:C 2 234628308 C G 7.46678e-05 0.773259 33.6705 6.5E-09 0.548867 24.4 UGT1A4 missense lost 2:234664586_ATC_A 0.640054397921 121083.0 0.00017798494921 -0.572402 1.34636214735 rs1976391 121975.0 0.00017383367716 UGT1A9 0.0000 0.0000 0.0059 0.0000 biochemistry_TotalBilirubin_v2 2:234638011:A:C 2 234638011 C A 0.000192535 0.687546 57.5679 3.3E-14 0.517158 21.7 UGT1A3 missense lost rs540313674 0.723328676649 316.737 0.131467157056 -0.478189 1.28687527346 rs1976391 121975.0 0.000296149681 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234638205:T:TC 2 234638205 TC T 0.000736399 0.788898 33.3179 7.8E-09 -0.178755 23.3 UGT1A3 frameshift lost rs34707303 1.02969756101 733.179 0.046792611856 0.19696 0.00723904217291 rs1976391 121975.0 0.00022048092196 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 2:234669255:C:T 2 234669255 T C 6.06696e-05 0.754928 34.998 3.3E-09 0.694592 22.4 UGT1A1 missense lost rs190246468 0.385841875373 1280.25 0.010547700804 -0.428877 5.02285859672 rs3771341 102858.0 0.00010067312896 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234669457:T:A 2 234669457 A T 7.35931e-05 0.938996 58.728 1.8E-14 0.718935 25.2 UGT1A1 missense lost 2:234929528_GT_G 0.609227079643 112.164 0.318985484944 -0.622418 2.82875634786 rs1976391 121975.0 0.00014181237225 UGT1A9 0.0012 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234669768:A:T 2 234669768 T A 0.000156602 0.704405 119.507 8.1E-28 0.795098 25.4 UGT1A1 missense lost rs565790231 0.359170607197 341.764 0.125593689664 -0.464013 19.1872940883 rs1976391 121975.0 0.00019796208601 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234675717:G:A 2 234675717 A G 3.19221e-05 0.596742 30.0179 4.3E-08 0.984717 28.2 UGT1A10 missense lost rs765129908 0.158467166043 356.894 0.013328471601 -0.483814 10.875739518 2:234657512:G:T 4523.87 0.000935197561 UGT1A9 0.0002 0.0281 0.0002 0.0000 biochemistry_TotalBilirubin_v2 2:234675807:A:G 2 234675807 G A 4.73413e-05 0.632372 34.2808 4.8E-09 0.890155 27.2 UGT1A10 missense lost 2:234763112:T:A 0.0192471813094 101.867 0.00647715916864 0.635829 25.4287692903 rs541394399 780.513 0.00030382581636 UGT1A9 0.0001 0.0000 0.0018 0.0067 biochemistry_TotalBilirubin_v2 2:234676526:C:T 2 234676526 T C 0.000297907 0.922925 79.9943 3.8E-19 0.401141 23.0 UGT1A10 missense lost rs112233788 1.04537704269 72621.8 0.00115150278244 -0.541356 0.0402699874918 rs1976391 121975.0 0.00052429550625 UGT1A9 0.0000 0.0075 0.0141 0.0000 biochemistry_TotalBilirubin_v2 2:234676880:C:T 2 234676880 T C 6.33496e-05 0.910146 51.0729 8.9E-13 0.693255 24.4 UGT1A10 missense lost rs554459516 0.666012492675 81.6001 0.416852300881 -0.697203 1.72732243961 rs1976391 121975.0 0.00016475519449 UGT1A9 0.0009 0.0004 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234676999:TA:T 2 234676999 T TA 5.99906e-05 0.807299 36.8052 1.3E-09 0.621116 26.7 UGT1A10 frameshift lost rs4663332 0.180034650311 65833.5 0.00010065105625 -0.418299 12.1981577144 rs4663332 65833.5 0.00010065105625 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 2:234680925:T:C 2 234680925 C T 0.00012879 0.890015 39.6705 3.0E-10 0.439995 23.6 UGT1A10 missense lost rs149780205 0.795888300363 5993.64 0.00526779833616 -0.409465 0.461640065586 rs1976391 121975.0 0.00024355347844 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234680927:C:T 2 234680927 T C 0.00019799 0.867142 62.8085 2.3E-15 0.466093 34 UGT1A10 missense lost rs139257330 0.706550045138 7984.43 0.00555798579361 -0.40618 1.59655560791 rs1976391 121975.0 0.00031264605124 UGT1A9 0.0186 0.0020 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234681098:G:A 2 234681098 A G 9.43499e-05 0.776077 35.1293 3.1E-09 0.494912 21.3 UGT1A10 missense lost rs929596 0.512422863483 94657.9 0.00019016961604 -0.528289 2.83663863834 rs1976391 121975.0 0.00013551753744 UGT1A9 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234688427:A:G 2 234688427 G A 0.00107053 0.959465 263.017 3.8E-59 0.384293 23.8 MROH2A missense lost 2:234673309:C:T 1.00073247926 121086.0 0.00217374142756 0.569018 3.5265941344e-05 rs1976391 121975.0 0.00217088901184 MROH2A 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234698550:C:T 2 234698550 T C 0.00680596 0.858137 454.523 7.5E-101 -0.211284 25.7 MROH2A missense lost rs142854795 0.819161663799 1369.62 0.2718475321 0.223615 4.09555238575 rs1976391 121975.0 0.00235592773641 MROH2A 0.0012 0.0000 0.0004 0.0000 biochemistry_TotalBilirubin_v2 2:234701492:A:G 2 234701492 G A 0.000754547 0.90022 40.0275 2.5E-10 0.193126 24.5 MROH2A missense lost 2:234622429:T:C 1.01513343853 62005.3 0.00065531904064 0.384042 0.00227460515088 rs1976391 121975.0 0.00037008525376 MROH2A 0.0473 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234702346:A:G 2 234702346 G A 0.00630654 0.936211 76.8847 1.8E-18 -0.0863842 20.3 MROH2A missense lost rs757033689 1.00055628687 5668.97 0.0135699201 0.140061 5.94643648429e-06 rs1976391 121975.0 0.00157303458225 MROH2A 0.1689 0.0000 0.0005 0.0000 biochemistry_TotalBilirubin_v2 2:234704848:C:T 2 234704848 T C 0.000316496 0.859269 69.0571 9.6E-17 0.408322 29.4 MROH2A missense lost rs35475316 0.951480305548 12553.6 0.00523407393961 -0.423373 0.0416598224978 rs1976391 121975.0 0.00047427257284 MROH2A 0.0036 0.0005 0.0203 0.0000 biochemistry_TotalBilirubin_v2 2:234707477:T:A 2 234707477 A T 0.000180813 0.858249 53.3319 2.8E-13 0.429374 22.8 MROH2A missense lost rs6722076 0.591919623992 102138.0 0.00030907398025 -0.538633 2.83690329465 rs1976391 121975.0 0.00025006361956 MROH2A 0.0000 0.0000 0.0000 0.0037 biochemistry_TotalBilirubin_v2 2:234710850:A:G 2 234710850 G A 0.000110052 0.916811 32.2047 1.4E-08 0.44933 23.2 MROH2A missense lost 2:234604081_CTTT_C 0.961212048498 88224.4 0.00035087283856 -0.5466 0.0123538087117 rs1976391 121975.0 0.00022632795364 MROH2A 0.0041 0.0003 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234712127:G:T 2 234712127 T G 0.00117184 0.796816 106.856 4.8E-25 -0.256905 24.3 MROH2A missense lost rs192706104 0.559241919925 207.898 0.287440738225 0.20373 6.79522259114 rs1976391 121975.0 0.00040649011456 MROH2A 0.0000 0.0000 0.0000 0.0156 biochemistry_TotalBilirubin_v2 2:234725427:C:T 2 234725427 T C 0.00715679 0.970682 288.445 1.1E-64 -0.153985 22.0 MROH2A missense lost 2:234644514_CAG_C 1.00827211527 4600.37 0.063219056356 0.231331 0.00491411661567 rs1976391 121975.0 0.00200927166001 MROH2A 0.0000 0.1297 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234725513:C:CCA 2 234725513 CCA C 0.0017857 0.881263 48.7218 2.9E-12 -0.140729 24.0 MROH2A frameshift lost 2:234665659:T:G 0.915330281668 73492.9 0.00060681424896 0.415373 0.0912259120996 rs1976391 121975.0 0.00026540971396 N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 2:234737414:G:A 2 234737414 A G 0.000296558 0.868625 40.4259 2.0E-10 -0.309053 25.1 MROH2A missense lost rs28948391 1.06190555881 793.776 0.054081362916 0.347599 0.0375766561791 rs1976391 121975.0 0.00011192370436 MROH2A 0.0000 0.0000 0.0000 0.0001 biochemistry_TotalBilirubin_v2 2:234737636:A:G 2 234737636 G A 0.000547231 0.924111 122.041 2.3E-28 0.370264 22.5 MROH2A missense lost rs28900371 0.998090173436 9600.25 0.012687994881 -0.428022 0.000111390623911 rs1976391 121975.0 0.000863713321 MROH2A 0.0011 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234737719:G:A 2 234737719 A G 0.00038021 0.937681 36.9588 1.2E-09 -0.242226 23.0 MROH2A splice_donor lost 2:234673309:C:T 0.582999518928 121086.0 0.00017794759609 0.569018 2.06641882221 rs1976391 121975.0 0.000176384961 MROH2A 0.0028 0.0000 0.0075 0.9756 biochemistry_TotalBilirubin_v2 2:234741266:C:G 2 234741266 G C 0.00135588 0.936858 48.3183 3.6E-12 -0.146645 22.7 MROH2A missense lost rs4477910 0.99765532471 78209.8 0.00061635510225 -0.437768 6.64854565799e-05 rs1976391 121975.0 0.00040912343824 MROH2A 0.0021 0.0000 0.0138 0.0462 biochemistry_TotalBilirubin_v2 2:234847793:G:A 2 234847793 A G 9.56944e-05 0.83222 30.668 3.1E-08 0.485209 26.1 TRPM8 missense lost 2:234726744:G:A 0.940728153618 56.7925 0.507994031169 0.432302 0.0277644435095 rs1976391 121975.0 0.00015659018496 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234851262:A:G 2 234851262 G A 0.000214187 0.738988 96.3153 9.8E-23 0.598106 24.3 TRPM8 missense lost rs180688822 1.12557517516 266.918 0.406155113809 -1.0268 0.3575821624 rs1976391 121975.0 0.00031488147601 TRPM8 0.0000 0.0061 0.2138 0.0000 biochemistry_TotalBilirubin_v2 2:234869523:C:T 2 234869523 T C 0.000659186 0.896794 31.4057 2.1E-08 0.192866 23.7 TRPM8 missense lost rs12987866 0.991109314871 89658.7 0.00034716632976 -0.521383 0.000623384503378 rs1976391 121975.0 0.00021786055201 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234878910:C:T 2 234878910 T C 0.00158214 0.961959 99.1562 2.3E-23 0.19623 25.9 TRPM8 missense lost rs35984508 1.00000958145 94142.9 0.001053262116 -0.497415 2.27572858429e-09 rs1976391 121975.0 0.00103084660624 TRPM8 0.0000 0.0000 0.0003 0.0000 biochemistry_TotalBilirubin_v2 2:234891850:G:A 2 234891850 A G 0.00363243 0.972335 99.413 2.0E-23 0.127579 24.8 TRPM8 missense lost rs929596 0.897637053418 94657.9 0.00094272947521 -0.528289 0.274664075514 rs1976391 121975.0 0.00053392882761 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 2:234915578:C:T 2 234915578 T C 0.000331843 0.809807 50.3679 1.3E-12 0.346534 22.2 TRPM8 missense lost rs6744284 0.99480551035 97096.9 0.00051604391556 -0.525677 0.000340651100309 rs1976391 121975.0 0.00043948510321 TRPM8 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 3:119531656:C:G 3 119531656 G C 0.000145644 0.925744 47.7445 4.9E-12 0.483038 23.4 NR1I2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A NR1I2 0.5027 0.0000 0.0045 0.0000 biochemistry_TotalBilirubin_v2 3:170727780:TTATAAG:T 3 170727780 T TTATAAG 0.000218032 0.667056 30.9903 2.6E-08 -0.461472 20.9 SLC2A2 inframe_deletion won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_TotalBilirubin_v2 4:74274363:A:G 4 74274363 G A 0.000780844 0.878554 47.6783 5.0E-12 0.23038 24.7 ALB missense won N/A N/A N/A N/A N/A N/A rs188611325 47.0753 0.5993701561 ALB 0.0000 0.0000 0.0000 0.0000 biochemistry_TotalBilirubin_v2 4:74275118:G:A 4 74275118 A G 2.09367e-05 0.687244 52.1567 5.1E-13 1.39699 22.8 ALB missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ALB 0.1193 0.0285 0.0001 0.0000 biochemistry_TotalBilirubin_v2 6:49604368:C:T 6 49604368 T C 0.000237916 0.858624 35.6394 2.4E-09 0.332175 34 RHAG splice_donor won N/A N/A N/A N/A N/A N/A N/A N/A N/A RHAG 0.0004 0.0000 0.3148 0.9729 biochemistry_TotalBilirubin_v2 7:100225847:C:T 7 100225847 T C 0.00514499 0.994125 32.0142 1.5E-08 0.0666456 21.6 NONE N/A lost 7:100239422:G:A 0.991582590463 32.5052 0.976604462289 0.0663091 0.000569473070401 rs35903783 66.2931 0.000100500625 TFR2 0.0014 0.0000 0.5241 0.4540 biochemistry_TotalBilirubin_v2 7:100319633:G:A 7 100319633 A G 0.00530564 0.826534 57.8017 2.9E-14 -0.107795 23.9 EPO missense won N/A N/A N/A N/A N/A N/A 7:100275444:G:A 56.5371 0.975341908836 EPO 0.0020 0.0000 0.0001 0.1020 biochemistry_TotalBilirubin_v2 8:41575677:G:A 8 41575677 A G 0.00135647 0.91167 54.1942 1.8E-13 0.185274 29.2 ANK1 missense won rs569451 0.00113078883273 172.102 0.00035608067401 0.0256663 50.6106833841 rs4737010 271.276 0.00017401303396 ANK1 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_TotalProtein_v2 10:52573772:C:T 10 52573772 T C 0.00991328 0.962839 34.706 3.8E-09 0.0598994 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs150770378 30.6984 0.870472206081 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_TotalProtein_v2 14:94847386:G:A 14 94847386 A G 0.0042676 0.970109 61.122 5.4E-15 0.122493 23.1 SERPINA1 missense won rs61980636 0.041384560746 153.994 0.016426010896 -0.0318975 38.7831710854 14:94795492:A:G 156.436 0.016039715904 SERPINA1 0.0004 0.0000 0.0301 0.0000 biochemistry_TotalProtein_v2 16:12060097:G:A 16 12060097 A G 0.000623018 0.924719 48.5453 3.2E-12 -0.304986 22.4 TNFRSF17 missense won rs563751993 0.000141543027096 54.7987 0.00012539072484 -0.0162154 47.3970663528 rs8062322 58.6019 0.00010564345089 TNFRSF17 0.0217 0.0028 0.0001 0.0000 biochemistry_TotalProtein_v2 16:12061582:C:T 16 12061582 T C 0.000194352 0.819705 55.1367 1.1E-13 -0.632616 27.0 TNFRSF17 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TNFRSF17 0.0648 0.0000 0.0000 0.0000 biochemistry_TotalProtein_v2 17:16852187:A:G 17 16852187 G A 0.00697641 0.947032 380.547 9.5E-85 -0.250573 26.1 TNFRSF13B missense won rs4383187 0.00201424547511 586.724 0.00130643210916 -0.0662274 347.155352861 17:16842991:G:A 1039.45 0.00066186309289 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 biochemistry_TotalProtein_v2 19:50017217:G:A 19 50017217 A G 1.85172e-05 0.500692 35.5534 2.5E-09 -2.141 25.7 FCGRT missense won N/A N/A N/A N/A N/A N/A rs7257387 30.5587 0.00015831427329 FCGRT 0.0117 0.0000 0.0002 0.0000 biochemistry_TotalProtein_v2 19:50017538:G:C 19 50017538 C G 0.00820013 0.955029 691.912 1.7E-152 -0.313116 22.6 FCGRT missense won N/A N/A N/A N/A N/A N/A 19:50016759:C:T 646.979 0.00094120717681 FCGRT 0.0108 0.0000 0.0006 0.0000 biochemistry_TotalProtein_v2 19:50154190:G:A 19 50154190 A G 0.00540921 0.95981 67.3453 2.3E-16 -0.120608 23.2 SCAF1 missense lost rs117080418 0.96580752146 253.753 0.256322476089 0.167436 0.0200276651272 19:50016759:C:T 646.979 0.00053730312804 SCAF1 0.0001 0.0000 0.0000 0.0000 biochemistry_TotalProtein_v2 1:161494958:C:G 1 161494958 G C 0.00182357 0.844758 50.5799 1.1E-12 -0.187613 20.9 HSPA6 missense lost 1:161494962:T:C 1.00018189043 50.5891 1.0 -0.187633 4.18309957472e-07 rs2926468 1728.05 0.00152843466304 HSPA6 0.0001 0.0000 0.0040 0.0000 biochemistry_TotalProtein_v2 1:161495757:C:T 1 161495757 T C 0.00452523 0.940628 50.2434 1.4E-12 0.1154 36 HSPA6 stop_gained lost rs532599492 0.66595613894 55.4299 0.603643533025 -0.129818 1.69990626869 rs2926468 1728.05 0.00262603977601 HSPA6 0.0006 0.0000 0.0006 0.0000 biochemistry_TotalProtein_v2 7:2296552:A:G 7 2296552 G A 0.00376927 0.988495 340.092 6.1E-76 -0.312468 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs559517076 258.845 0.756980042116 SNX8 0.0000 0.0000 0.0000 0.0001 biochemistry_TotalProtein_v2 7:2354052:G:A 7 2354052 A G 0.000210798 0.827124 32.9152 9.6E-09 -0.423232 26.1 SNX8 missense won rs138024992 0.00037667216109 33.4565 0.00037057790016 -0.0159901 31.6499589581 7:2492958_CTATT_C 57.5989 0.00012092081296 SNX8 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Triglycerides_v2 10:52573772:C:T 10 52573772 T C 0.00987401 0.962839 126.338 2.6E-29 0.116859 23.4 A1CF missense won N/A N/A N/A N/A N/A N/A rs150770378 105.258 0.868993111204 A1CF 0.0161 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 10:71883836:C:A 10 71883836 A C 0.00750755 0.887584 32.3994 1.3E-08 0.0658386 25.1 AIFM2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A AIFM2 0.0000 0.0000 0.0008 0.0000 biochemistry_Triglycerides_v2 11:14865399:C:T 11 14865399 T C 0.00106081 0.906863 226.771 3.0E-51 -0.465058 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs558528882 110.662 0.443895725025 PDE3B 0.1111 0.0139 0.0003 0.0000 biochemistry_Triglycerides_v2 11:14891141:G:C 11 14891141 C G 0.0066105 0.980636 53.4052 2.7E-13 -0.086906 22.6 PDE3B missense lost rs188198602 0.957827633303 55.6842 0.9186264025 0.0918407 0.0242597002303 rs143019979 89.0768 0.052211336004 PDE3B 0.0001 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 11:46332586:A:T 11 46332586 T A 0.00587584 0.960249 31.3458 2.2E-08 -0.0718686 23.7 CREB3L1 missense lost rs149903077 0.964209003536 65.2811 0.462980902329 0.074339 0.0102222217683 rs1055447 87.8529 0.00436216658089 CREB3L1 0.0485 0.0000 0.0007 0.0000 biochemistry_Triglycerides_v2 11:70007354:G:A 11 70007354 A G 0.00620328 0.96012 30.8749 2.8E-08 -0.0708106 23.4 ANO1 missense lost rs553652823 0.711398576769 31.8943 0.688660980736 0.069335 0.75673248195 rs4980659 43.0745 0.00028635069961 ANO1 0.0001 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 11:116661001:G:A 11 116661001 A G 0.000410001 0.941055 75.3798 3.9E-18 0.429211 24.4 APOA5 missense won 11:116638691_AAAT_A 0.0214693540045 2947.56 0.00054904925124 0.108639 54.908219234 11:116638691_AAAT_A 2947.56 0.00054904925124 APOA5 0.0002 0.0000 0.0007 0.0000 biochemistry_Triglycerides_v2 11:116661122:G:A 11 116661122 A G 0.000106302 0.98376 107.035 4.4E-25 0.959171 35 APOA5 stop_gained won 11:116663707:A:G 0.0833210628672 5322.38 0.00167561691649 0.293601 54.1611337136 11:116648917:C:G 9982.85 0.00066157498521 APOA5 0.0020 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 11:116661392:C:A 11 116661392 A C 0.000160685 0.926507 38.4159 5.7E-10 0.471452 22.7 APOA5 missense lost rs76240380 0.769547029995 47.915 0.616985114256 -0.384468 0.57894435025 11:116663707:A:G 5322.38 0.00229291576336 APOA5 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 11:116661656:G:A 11 116661656 A G 0.000259799 0.934111 236.032 2.9E-53 0.955462 37 APOA5 stop_gained won rs180327 0.00493167478249 2662.76 0.00043715282724 0.103171 204.044921361 rs180327 2662.76 0.00043715282724 APOA5 0.0000 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 11:116662297:C:G 11 116662297 G C 0.000156141 0.802277 189.515 4.1E-43 1.16205 22.1 NONE N/A won 11:116663707:A:G 0.050811653886 5322.38 0.00180926025316 0.293601 113.705748739 11:116648917:C:G 9982.85 0.000738806761 APOA5 0.0004 0.0001 0.0134 0.9766 biochemistry_Triglycerides_v2 11:116701353:C:T 11 116701353 T C 0.000177428 0.815693 334.137 1.2E-74 -1.41431 35 APOC3 stop_gained won rs1729408 0.000710511667004 762.047 0.00031154015025 0.0565436 316.561280938 rs1268353 1416.64 0.00015602008464 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 11:116701354:G:A 11 116701354 A G 0.00223041 0.92045 3614.07 2.2E-787 -1.2616 31 APOC3 splice_donor won 11:116623213_TA_T 0.000717467992561 9608.98 0.00026984961441 0.268719 3423.05296333 11:116648917:C:G 9982.85 0.00024675697225 APOC3 0.0001 0.0000 0.1104 0.8914 biochemistry_Triglycerides_v2 11:116701549:C:A 11 116701549 A C 2.02475e-05 0.923653 36.1445 1.8E-09 -1.33912 22.9 APOC3 missense won rs142511874 0.000514808963267 173.455 0.00010727573476 0.03131 34.5229133312 rs142511874 173.455 0.00010727573476 APOC3 0.0039 0.0000 0.0050 0.0000 biochemistry_Triglycerides_v2 11:116701560:G:A 11 116701560 A G 0.000389494 0.859578 317.158 6.0E-71 -0.944085 23.2 APOC3 missense won rs7118999 0.00148495825694 4177.07 0.00011275041856 0.143338 293.185500304 rs7118999 4177.07 0.00011275041856 APOC3 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 11:116707044:A:T 11 116707044 T A 0.000847994 0.946132 63.2788 1.8E-15 0.258906 25.2 APOA1 missense lost 11:116660686:A:G 0.925391185296 5620.11 0.010419305625 0.284305 0.0915066512591 11:116648917:C:G 9982.85 0.00492959856321 APOA1 0.0005 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 11:117077793:C:T 11 117077793 T C 0.000478116 0.884219 42.0797 8.8E-11 0.286093 23.3 PCSK7 missense lost 11:116663707:A:G 0.445701853226 5322.38 0.00352379955456 0.293601 4.64912258653 11:116648917:C:G 9982.85 0.00138918707524 PCSK7 0.0004 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 12:109661672:A:G 12 109661672 G A 0.00198617 0.775439 106.198 6.7E-25 -0.253482 24.1 ACACB missense won N/A N/A N/A N/A N/A N/A rs182724639 52.5152 0.3282487849 ACACB 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 13:45970147:A:G 13 45970147 G A 0.00632871 0.912642 40.0099 2.5E-10 0.0753369 25.5 SLC25A30 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SLC25A30 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 15:43705365:G:A 15 43705365 A G 0.000665085 0.87151 42.6921 6.4E-11 0.263633 26.7 TP53BP1 missense lost 15:44011204_CAGAG_C 0.882101127183 555.082 0.067843579024 -0.247295 0.157804923516 rs139974673 754.359 0.020167124121 TP53BP1 0.0000 0.0000 0.0000 0.0006 biochemistry_Triglycerides_v2 15:58840586:C:T 15 58840586 T C 0.00142472 0.933085 35.9578 2.0E-09 0.160181 23.9 LIPC missense lost 15:58726744:C:G 0.0208197624904 507.797 0.00147427585369 0.0529888 26.3296914601 rs1077835 511.612 0.00140418825625 LIPC 0.0033 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 15:58855748:C:T 15 58855748 T C 0.00197608 0.925982 51.3263 7.8E-13 0.162109 24.2 LIPC missense won rs2043084 0.00185895550583 208.426 0.00045778025764 -0.0337951 46.9957842216 rs753768034 318.118 0.00019019995569 LIPC 0.0024 0.0569 0.0000 0.0000 biochemistry_Triglycerides_v2 15:90210353:CTTCTGCAGGGT:C 15 90210353 C CTTCTGCAGGGT 0.00029687 0.910204 39.4454 3.4E-10 -0.377948 28.7 PLIN1 frameshift won N/A N/A N/A N/A N/A N/A 15:90210367:G:C 39.4454 1.0 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 15:90210367:G:C 15 90210367 C G 0.00029687 0.910204 39.4454 3.4E-10 -0.377948 21.3 PLIN1 missense lost 15:90210353:CTTCTGCAGGGT:C 1.0 39.4454 1.0 -0.377948 0.0 15:90210353:CTTCTGCAGGGT:C 39.4454 1.0 PLIN1 0.0243 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 15:90214777:A:G 15 90214777 G A 0.00120388 0.93376 70.5184 4.6E-17 -0.24976 30 PLIN1 missense won N/A N/A N/A N/A N/A N/A rs565712230 46.7026 0.550900919529 PLIN1 0.0192 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 17:7534678:C:T 17 7534678 T C 0.0069238 0.973007 37.5649 8.8E-10 0.078805 23.4 SHBG missense lost 17:7559037:C:T 0.0316760831605 46.981 0.025327449316 0.0175968 25.3833753607 17:7193255:G:A 56.4233 0.00080363178256 SHBG 0.0000 0.0000 0.0356 0.0012 biochemistry_Triglycerides_v2 17:38510699:C:G 17 38510699 G C 0.000629345 0.95249 33.6277 6.7E-09 -0.221611 25.5 RARA missense lost rs377608878 0.550491426928 35.9611 0.514771810576 0.335642 2.23924290275 rs377608878 35.9611 0.514771810576 RARA 0.0139 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 17:41063408:C:T 17 41063408 T C 0.000368337 0.927043 30.6258 3.1E-08 0.296052 35 G6PC stop_gained lost 17:41914714_AC_A 0.00488376973748 566.298 0.00026411775289 -0.177076 26.4948641704 17:41926126:C:T 815.242 0.00013204767744 G6PC 0.0535 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 19:4168364:T:TG 19 4168364 TG T 8.00625e-05 0.893304 31.1939 2.3E-08 0.595401 35 CREB3L3 frameshift won N/A N/A N/A N/A N/A N/A 19:4168371:A:T 31.1939 1.0 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 19:4168371:A:T 19 4168371 T A 8.00625e-05 0.893304 31.1939 2.3E-08 0.595401 24.0 CREB3L3 missense lost 19:4168364:T:TG 1.0 31.1939 1.0 0.595401 0.0 19:4168364:T:TG 31.1939 1.0 CREB3L3 0.0001 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 19:7125518:C:T 19 7125518 T C 0.00683043 0.939687 50.9618 9.4E-13 -0.0901545 26.2 INSR missense won rs762433880 0.0089385144992 72.2461 0.006305154025 0.0191572 41.7810867537 rs3890483 133.281 0.00104381332561 INSR 0.0725 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 19:8435987:T:G 19 8435987 G T 7.10456e-05 0.885544 32.7464 1.1E-08 -0.677683 26.6 ANGPTL4 missense lost rs118059146 0.00270230989029 198.416 0.00044598681856 0.0435084 29.430329814 rs118059146 198.416 0.00044598681856 ELAVL1 0.0051 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 19:8435993:C:T 19 8435993 T C 0.000536448 0.677317 41.6182 1.1E-10 -0.330928 25.9 ANGPTL4 missense won 19:7970635:A:G 0.000346047108313 72.5442 0.00019852528201 -0.0169975 40.0842099219 19:8458960:T:C 118.375 0.000118853604 ELAVL1 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 19:11350874:C:T 19 11350874 T C 0.000481482 0.861956 144.84 2.3E-33 -0.542413 36 C19orf80 stop_gained won rs116846441 0.0160645392586 461.652 0.00504013383721 0.320751 110.451017165 19:8429323:G:A 1223.59 0.00097954602529 DOCK6 0.0004 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 19:19380516:A:G 19 19380516 G A 0.000601564 0.918106 30.4351 3.5E-08 -0.228458 25.2 TM6SF2 missense lost 19:19217177:C:T 0.99982442951 36.3536 0.837049329216 -0.274576 2.34561057075e-07 rs2074551 292.88 0.00111699666225 TM6SF2 0.0000 0.0000 0.0000 0.0018 biochemistry_Triglycerides_v2 19:41754430:G:A 19 41754430 A G 0.00782617 0.954313 68.4651 1.3E-16 -0.0893171 31 AXL missense won N/A N/A N/A N/A N/A N/A rs180958600 66.549 0.898184571076 AXL 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 1:63063592:GAACTC:G 1 63063592 G GAACTC 0.000624761 0.889289 278.322 1.7E-62 -0.67485 34 ANGPTL3 frameshift won rs370129568 0.000789073907915 673.855 0.000325910809 -0.0556435 262.90523096 rs1183851 695.919 0.00030548747524 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 1:63063667:CAACT:C 1 63063667 C CAACT 0.00023831 0.856004 71.9077 2.3E-17 -0.518583 33 ANGPTL3 frameshift won rs646179 0.00136246945386 693.02 0.00014136972201 0.0522229 66.6972092156 rs1183851 695.919 0.00014063825281 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 1:63067475:G:T 1 63067475 T G 0.000230713 0.884257 45.788 1.3E-11 -0.474163 26.0 ANGPTL3 missense won rs11208009 0.00633826583078 1179.74 0.00024600040336 -0.0676563 38.7875556876 rs11208009 1179.74 0.00024600040336 DOCK7 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 1:63069706:T:G 1 63069706 G T 0.000412556 0.870862 180.568 3.6E-41 -0.671411 26.5 ANGPTL3 missense won 1:63131385_CAA_C 0.000986383396971 298.323 0.00059703501649 0.04316 169.404004363 1:63130453_TA_T 505.831 0.00011988498064 DOCK7 0.0064 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 1:64089252:C:T 1 64089252 T C 0.00044744 0.922106 61.3056 4.9E-15 -0.372446 25.1 PGM1 missense lost rs574313788 0.915935699616 88.9963 0.630947439684 0.508378 0.113115364109 1:63069706:T:G 180.568 0.192713098081 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 20:44470575:G:A 20 44470575 A G 0.00962477 0.948854 32.1661 1.4E-08 0.0562685 24.3 ACOT8 missense lost rs565656862 0.958402746088 42.3717 0.727562938729 -0.061222 0.014211656985 rs6073958 755.397 0.029829434944 ACOT8 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 20:44519224:C:CT 20 44519224 CT C 0.00816423 0.955902 33.7817 6.2E-09 0.0623468 33 NEURL2 frameshift lost 20:44554015:T:C 0.665141613207 742.219 0.030273564049 0.0671346 1.14916297217 rs6073958 755.397 0.027956174401 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 2:21228587:G:C 2 21228587 C G 1.87821e-05 0.805907 55.9718 7.4E-14 -1.81066 35 APOB stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A APOB 0.0000 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 2:21228891:CA:C 2 21228891 C CA 0.000147236 0.642863 224.966 7.5E-51 -1.49216 25.3 APOB frameshift won 2:21237544:G:A 0.00198807757723 1190.27 0.00037575496336 -0.0839304 205.351743231 rs2678379 1226.39 0.00035639021089 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 2:21229160:C:T 2 21229160 T C 0.00035997 0.96006 33.5111 7.1E-09 -0.308747 24.9 APOB missense lost rs952275 0.0046838033806 451.505 0.000347636025 -0.041149 29.0811727619 rs952275 451.505 0.000347636025 APOB 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 2:21229501:AG:A 2 21229501 A AG 3.6762e-05 0.888846 37.3241 1.0E-09 -1.0459 35 APOB frameshift won rs11899291 0.000144398006285 45.8822 0.00011746441161 0.0154809 36.4324740443 rs11899291 45.8822 0.00011746441161 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 2:21232176:G:A 2 21232176 A G 3.06447e-05 0.967799 72.2064 1.9E-17 -1.47244 37 APOB stop_gained won rs78669806 0.000529868761615 105.039 0.00036424485904 0.0389255 68.9204392368 rs78669806 105.039 0.00036424485904 APOB 0.0000 0.0000 0.0064 0.0000 biochemistry_Triglycerides_v2 2:21255263:G:A 2 21255263 A G 0.000136758 0.667184 79.4878 4.9E-19 -0.899135 37 APOB stop_gained won rs76611756 0.00203150377843 113.078 0.00142803875236 0.04705 72.4838987303 rs581998 126.333 0.00015586024336 APOB 0.0000 0.0000 0.0001 0.0013 biochemistry_Triglycerides_v2 2:21260958:C:A 2 21260958 A C 2.9838e-05 0.788057 126.011 3.1E-29 -2.26295 34 APOB stop_gained won N/A N/A N/A N/A N/A N/A rs566327234 52.4972 0.380930902416 APOB 0.0000 0.5731 0.0142 0.0000 biochemistry_Triglycerides_v2 2:26534339:T:G 2 26534339 G T 4.4766e-05 0.681414 35.5314 2.5E-09 -1.11898 26.8 GPR113 missense won 2:27470531:G:A 0.00169800996731 117.337 0.00051418283536 -0.0681255 32.6634538056 rs181391993 231.126 0.00012522505216 ADGRF3 0.0020 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 2:26818069:C:A 2 26818069 A C 0.00900474 0.96051 35.6315 2.4E-09 -0.0602464 25.6 CIB4 missense lost rs145430594 0.558466973529 76.4315 0.260350980516 0.0606265 2.27521435558 2:27730940:T:C 3508.42 0.00187208520976 CIB4 0.0000 0.0000 0.0001 0.0667 biochemistry_Triglycerides_v2 2:27726437:A:C 2 27726437 C A 0.00377672 0.950472 41.2857 1.3E-10 0.102164 22.6 GCKR missense lost 2:27700378:T:C 0.994383194829 42.4743 0.966556394496 0.108021 0.000326543190463 rs141306206 2292.99 0.00437615325625 GCKR 0.0000 0.0000 0.0001 0.0243 biochemistry_Triglycerides_v2 2:28113157:A:G 2 28113157 G A 0.00498505 0.946225 47.8795 4.5E-12 0.0902046 22.2 RBKS missense lost 2:27715225:G:A 0.824021529971 60.7583 0.649355542276 0.09672 0.407401741733 2:27730940:T:C 3508.42 0.00629328063204 RBKS 0.0003 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 2:28117455:C:G 2 28117455 G C 0.00435572 0.899929 29.8608 4.6E-08 0.0828275 26.4 BRE missense lost rs541694097 0.82994489692 81.3724 0.3045604969 -0.0762707 0.236457689242 2:27730940:T:C 3508.42 0.00510971921329 BRE 0.0128 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 2:219878668:T:C 2 219878668 C T 0.00449077 0.931881 51.0113 9.2E-13 0.109626 25.7 CCDC108 missense lost 2:219720952_TAGG_T 0.645667857111 337.655 0.097544407041 -0.0903557 1.96896744172 rs78058190 361.88 0.089136879364 CCDC108 0.0000 0.0000 0.0001 0.0000 biochemistry_Triglycerides_v2 4:110638764:A:G 4 110638764 G A 0.00170041 0.93174 71.956 2.2E-17 0.197251 25.5 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs113824614 30.0595 0.347135429124 PLA2G12A 0.0000 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 4:110638824:C:T 4 110638824 T C 0.00769829 0.943901 169.128 1.1E-38 0.145485 26.2 PLA2G12A missense won N/A N/A N/A N/A N/A N/A rs189866430 168.857 0.898235749009 PLA2G12A 0.2418 0.0000 0.0000 0.0000 biochemistry_Triglycerides_v2 4:155489608:C:T 4 155489608 T C 0.00593247 0.942434 61.1741 5.2E-15 0.103236 25.2 FGB missense won N/A N/A N/A N/A N/A N/A rs567444476 33.7374 0.618187490001 FGB 0.0001 0.0000 0.0018 0.0004 biochemistry_Triglycerides_v2 6:31964621:G:GCT 6 31964621 GCT G 0.00482986 0.569777 46.407 9.6E-12 0.130998 34 C4A frameshift lost rs187050905 0.353841985219 110.279 0.148901830884 -0.0886322 7.61769108347 rs202092176 217.752 0.029087984704 N/A N/A N/A N/A N/A biochemistry_Triglycerides_v2 7:73020411:A:G 7 73020411 G A 0.000270707 0.900866 44.3808 2.7E-11 0.412424 24.7 MLXIPL missense won 7:73029139_CT_C 0.00506331225598 1194.8 0.00018807653881 -0.0765153 38.2895086647 rs35348663 1803.98 0.00010176169129 MLXIPL 0.0000 0.0000 0.0002 0.0000 biochemistry_Triglycerides_v2 8:19362707:C:G 8 19362707 G C 0.0016188 0.925238 30.9339 2.7E-08 -0.122974 LOW NONE N/A lost 8:19363435:C:T 0.997451748463 31.0487 0.993763753129 -0.123569 5.02820703042e-05 8:19819328:T:C 4356.78 0.00522221577201 CSGALNACT1 0.0004 0.0000 0.0003 0.5181 biochemistry_Triglycerides_v2 8:19811733:G:A 8 19811733 A G 0.00043763 0.837003 195.399 2.1E-44 0.705786 23.3 LPL missense won 8:19890654:T:C 0.00526623752187 417.439 0.00246507285025 0.0576949 168.068257365 8:19824667:C:T 3771.51 0.00015051118489 LPL 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Urate_v2 10:16992011:G:A 10 16992011 A G 0.00255759 0.913785 37.1716 1.1E-09 0.112893 24.9 CUBN missense lost rs184374646 0.874312151311 37.9772 0.855765605776 -0.12247 0.156824886732 rs184374646 37.9772 0.855765605776 CUBN 0.0000 0.0000 0.0001 0.0091 biochemistry_Urate_v2 11:48285468:G:A 11 48285468 A G 3.22129e-05 0.917277 36.5449 1.5E-09 -1.08441 25.3 OR4X1 stop_gained won 11:47479638_CAAAAAAAAAAA_C 0.000244953615568 51.5832 0.00017354110225 0.0204622 35.4099237786 rs528033493 51.9729 0.00015912561025 OR4X1 0.0005 0.0000 0.0804 0.0000 biochemistry_Urate_v2 11:61674116:A:G 11 61674116 G A 3.70683e-05 0.915661 43.2819 4.7E-11 -1.1116 27.6 RAB3IL1 missense lost 11:61570945:T:C 1.02284557748 44.2707 1.0 -1.12314 0.0055838240046 11:64366298:C:T 1090.22 0.021358361025 RAB3IL1 0.0001 0.0000 0.0002 0.0000 biochemistry_Urate_v2 11:62293155:G:A 11 62293155 A G 2.87024e-05 0.865993 32.9896 9.3E-09 -1.0876 23.6 AHNAK missense lost rs528206273 0.918845371252 61.6764 0.491473906704 1.28948 0.0566406209761 11:64368212:C:T 105.704 0.27520516 AHNAK 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:62363313:G:A 11 62363313 A G 3.29302e-05 0.902754 48.9281 2.7E-12 -1.19007 25.4 MTA2 missense lost 11:64367239:G:A 0.0712720778821 324.449 0.010748090929 -1.14898 26.2908031382 11:64367239:G:A 324.449 0.010748090929 MTA2 0.0419 0.0000 0.0008 0.0000 biochemistry_Urate_v2 11:62389370:A:G 11 62389370 G A 8.42018e-05 0.526691 113.62 1.6E-26 -1.46086 22.7 B3GAT3 missense lost 11:64367152:G:A 0.291505738754 507.039 0.065322158724 -1.1141 24.0511169047 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 957.541 0.000103754596 B3GAT3 0.0004 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:62545525:G:C 11 62545525 C G 4.95096e-05 0.860535 32.2157 1.4E-08 -0.823586 28.7 TAF6L missense lost 11:64368271:C:T 0.535771463053 38.2325 0.451454985216 -0.663601 2.31448015727 rs17299124 451.778 0.000111197025 TAF6L 0.0000 0.0000 0.0001 0.0000 biochemistry_Urate_v2 11:64110027:G:A 11 64110027 A G 4.63982e-05 0.915062 66.5207 3.5E-16 -1.19731 26.1 CCDC88B missense lost 11:64367902:C:T 1.157087238 312.232 0.246516222016 -1.29622 0.380993757836 11:64367902:C:T 312.232 0.246516222016 CCDC88B 0.0007 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64116845:C:T 11 64116845 T C 0.00182736 0.953906 30.9343 2.7E-08 0.121439 25.0 CCDC88B missense lost rs528056794 1.14712714513 40.404 0.8782688656 -0.152361 0.156116513704 rs12363578 1382.83 0.00086188042084 CCDC88B 0.0127 0.0032 0.0005 0.0000 biochemistry_Urate_v2 11:64323613:C:T 11 64323613 T C 0.00511001 0.96801 111.335 5.0E-26 0.142534 35 SLC22A11 stop_gained lost rs78734635 0.44567654765 132.83 0.373555660864 -0.0954484 12.3021098597 rs12363578 1382.83 0.003602040289 SLC22A11 0.0001 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64337291:G:A 11 64337291 A G 2.01078e-05 0.870571 46.548 8.9E-12 -1.58113 20.2 SLC22A11 missense lost 11:64367853:C:T 0.792014277757 80.6493 0.457123379881 -1.41141 0.563724091964 rs561414621 157.632 0.00030593857921 SLC22A11 0.0801 0.0001 0.0000 0.0000 biochemistry_Urate_v2 11:64359069:G:A 11 64359069 A G 0.000270996 0.818712 291.309 2.6E-65 -1.06973 25.7 SLC22A12 missense won rs12797706 0.000673895457874 295.85 0.00066355184025 0.0384364 276.380841887 11:64387932:G:A 992.231 0.00010107487296 SLC22A12 0.0449 0.0000 0.0001 0.0000 biochemistry_Urate_v2 11:64359072:G:C 11 64359072 C G 4.02246e-05 0.895285 50.8386 1.0E-12 -1.10829 23.4 SLC22A12 missense won rs777010148 0.00253991345792 100.32 0.00128713760289 0.098543 45.8434434579 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 957.541 0.00011292462756 SLC22A12 0.3663 0.0000 0.0002 0.0000 biochemistry_Urate_v2 11:64359079:G:C 11 64359079 C G 0.000117352 0.70157 83.1155 7.7E-20 -0.939655 23.7 SLC22A12 missense won rs569925321 0.00980171442389 85.3277 0.00954759585924 0.186869 67.4727056112 rs72926005 132.863 0.00020569009561 SLC22A12 0.0099 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64359302:C:T 11 64359302 T C 0.000455244 0.768308 690.948 2.8E-152 -1.34062 22.2 SLC22A12 missense won 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 0.000265677267519 957.541 0.00019170894681 -0.0680541 668.607204106 11:64387932:G:A 992.231 0.00010299408196 SLC22A12 0.0153 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64360260:G:C 11 64360260 C G 9.35944e-05 0.957364 289.003 8.2E-65 -1.69346 23.6 SLC22A12 missense won N/A N/A N/A N/A N/A N/A rs527701659 178.848 0.793957627849 SLC22A12 0.0021 0.0022 0.0000 0.0000 biochemistry_Urate_v2 11:64360279:T:C 11 64360279 C T 0.000293843 0.812924 748.435 8.8E-165 -1.66116 23.8 SLC22A12 missense won rs12363578 0.000641048970453 1382.83 0.00034695767824 0.0720213 711.015614445 rs12363578 1382.83 0.00034695767824 SLC22A12 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64361028:C:G 11 64361028 G C 4.69362e-05 0.516591 89.4237 3.2E-21 -1.79456 24.0 SLC22A12 missense won 11:64900270:G:T 0.000230575056569 139.503 0.00014780237476 -0.0300608 86.7285750986 11:64900270:G:T 139.503 0.00014780237476 SLC22A12 0.0007 0.0000 0.0084 0.1745 biochemistry_Urate_v2 11:64367152:G:A 11 64367152 A G 0.000385003 0.927218 507.039 2.8E-112 -1.1141 21.9 SLC22A12 missense won 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 0.00150794867402 957.541 0.00079849195776 -0.0680541 468.424592643 11:64357072:T:C 1319.45 0.00010088394481 SLC22A12 0.2454 0.0023 0.0000 0.0000 biochemistry_Urate_v2 11:64367231:T:C 11 64367231 C T 1.86642e-05 0.768236 31.95 1.6E-08 -1.44495 20.8 SLC22A12 missense lost rs183873831 0.0249984860489 541.516 0.00147493634401 1.33778 22.6455304331 11:64366298:C:T 1090.22 0.00010398900625 SLC22A12 0.0061 0.0000 0.0006 0.0000 biochemistry_Urate_v2 11:64367290:C:G 11 64367290 G C 1.87494e-05 0.834751 32.619 1.1E-08 -1.36224 22.0 SLC22A12 missense lost 11:64368239:C:A 0.00731920900269 282.218 0.00084596049316 -1.60138 27.2764793869 11:64367152:G:A 507.039 0.00022309604496 SLC22A12 0.0000 0.0000 0.0001 0.0000 biochemistry_Urate_v2 11:64367362:G:A 11 64367362 A G 6.37801e-05 0.801049 102.283 4.8E-24 -1.31629 23.2 SLC22A12 missense won 11:64368239:C:A 0.00080884419435 282.218 0.00029314576225 -1.60138 96.5478358688 11:64367239:G:A 324.449 0.00012994176064 SLC22A12 0.0003 0.0000 0.0665 0.2500 biochemistry_Urate_v2 11:64367853:C:T 11 64367853 T C 4.32598e-05 0.878775 80.6493 2.7E-19 -1.41141 20.8 SLC22A12 missense won 11:64368239:C:A 0.00117461807564 282.218 0.00033567003369 -1.60138 75.2158933377 11:64367239:G:A 324.449 0.00014914515625 SLC22A12 0.0020 0.0286 0.0000 0.0000 biochemistry_Urate_v2 11:64367854:G:A 11 64367854 A G 0.000238425 0.895339 175.894 3.8E-40 -0.85738 23.3 SLC22A12 missense won rs113349712 0.000610334165957 1046.66 0.00010256828176 0.0676302 167.310451934 rs113349712 1046.66 0.00010256828176 SLC22A12 0.0016 0.0036 0.0000 0.0000 biochemistry_Urate_v2 11:64367902:C:T 11 64367902 T C 0.000180567 0.887621 312.232 7.1E-70 -1.29622 23.1 SLC22A12 missense won rs111169821 0.000281502246685 597.776 0.00014703502564 0.0527837 301.842619102 rs111169821 597.776 0.00014703502564 SLC22A12 0.0001 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64368212:C:T 11 64368212 T C 8.72908e-05 0.736515 105.704 8.6E-25 -1.23441 22.3 SLC22A12 missense won 11:64368239:C:A 0.000623728746551 282.218 0.00023361594025 -1.60138 100.490108422 rs55962027 427.576 0.00010417468356 SLC22A12 0.0018 0.0015 0.0006 0.0000 biochemistry_Urate_v2 11:64368235:G:A 11 64368235 A G 2.0323e-05 0.839665 40.394 2.1E-10 -1.41465 22.8 SLC22A12 missense won 11:64368239:C:A 0.00551428008587 282.218 0.00078926159844 -1.60138 34.6175724668 11:64367152:G:A 507.039 0.00020792198025 SLC22A12 0.0125 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64368239:C:A 11 64368239 A C 0.000116693 0.846722 282.218 2.5E-63 -1.60138 23.6 SLC22A12 missense lost rs775952762 0.675276492097 289.971 0.657221518864 1.39882 8.9667202033 rs775952762 289.971 0.657221518864 SLC22A12 0.0030 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64368271:C:T 11 64368271 T C 9.19132e-05 0.832484 38.2325 6.3E-10 -0.663601 24.7 SLC22A12 missense won rs72922857 0.00567735435231 130.494 0.00166336728336 0.0583806 32.6880577597 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 957.541 0.00012323442121 SLC22A12 0.0001 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64368382:C:T 11 64368382 T C 2.894e-05 0.847974 34.7156 3.8E-09 -1.1103 24.7 SLC22A12 missense lost 11:65123212:G:A 0.856850619771 35.3237 0.8420998756 -1.23057 0.191841862358 11:64383301_CGTGTGTGTGTGTGTGTGTGTGTGT_C 957.541 0.00012448757476 SLC22A12 0.0001 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64497613:G:C 11 64497613 C G 0.00354213 0.852364 78.1572 9.5E-19 -0.157817 24.4 RASGRP2 missense lost 11:64332779:G:T 0.891196784732 103.453 0.6732858916 -0.165537 0.244819240003 rs12363578 1382.83 0.00365752800625 RASGRP2 0.0015 0.0000 0.0005 0.0000 biochemistry_Urate_v2 11:64518016:G:A 11 64518016 A G 0.00362253 0.936847 39.3608 3.5E-10 0.100618 27.7 PYGM missense lost rs80034782 0.600555953837 79.1356 0.298707064681 -0.0817042 1.99342961401 rs12363578 1382.83 0.00236661817441 PYGM 0.0075 0.0002 0.0002 0.0000 biochemistry_Urate_v2 11:64527223:G:A 11 64527223 A G 0.00404074 0.937244 103.597 2.5E-24 0.158027 35 PYGM stop_gained lost 11:64597001:G:A 0.804877018658 118.998 0.700707948889 0.164642 1.0958748664 rs12363578 1382.83 0.00277605695689 PYGM 0.0001 0.0000 0.0001 0.0000 biochemistry_Urate_v2 11:64535630:G:A 11 64535630 A G 7.00075e-05 0.635304 156.386 7.0E-36 -1.79472 23.1 SF1 missense lost 11:64359302:C:T 0.351935500118 690.948 0.079655466289 -1.34062 25.8744486742 11:64359302:C:T 690.948 0.079655466289 SF1 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64820695:T:G 11 64820695 G T 0.00065873 0.904208 37.3015 1.0E-09 -0.250153 26.5 NAALADL1 missense lost rs2298405 0.950306450773 37.9943 0.932978264464 0.248106 0.023619134623 11:65557116:T:TG 748.69 0.00023556724324 NAALADL1 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64876153:C:T 11 64876153 T C 3.14373e-05 0.914516 30.5511 3.3E-08 -0.995688 28.6 VPS51 missense lost 11:64360985:G:A 0.883415051791 40.4852 0.666646122256 -0.990121 0.110344936573 11:64226550:G:A 93.7075 0.00021045595041 VPS51 0.0002 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64901005:T:C 11 64901005 C T 9.59751e-05 0.784405 49.4015 2.1E-12 -0.718748 27.8 SYVN1 missense lost 11:64359158:G:A 1.21178847086 98.7817 0.606024882576 -1.32848 0.502076762141 11:64473580_GTA_G 531.331 0.00010674402489 SYVN1 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:64953448:G:A 11 64953448 A G 0.000264621 0.914888 150.2 1.6E-34 -0.715824 28.3 CAPN1 missense lost 11:64368239:C:A 0.74782272598 282.218 0.398000742129 -1.60138 2.74683434534 rs775952762 289.971 0.385966472644 CAPN1 0.0072 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:65308738:CCTT:C 11 65308738 C CCTT 0.000105874 0.896964 164.401 1.2E-37 -1.24277 22.2 LTBP3 inframe_deletion lost rs775952762 0.719014924312 289.971 0.407650325625 1.39882 3.80094613043 rs775952762 289.971 0.407650325625 N/A N/A N/A N/A N/A biochemistry_Urate_v2 11:65352458:T:C 11 65352458 C T 0.00023851 0.723136 69.3196 8.4E-17 -0.636257 26.9 EHBP1L1 missense lost 11:64360260:G:C 0.972871877106 289.003 0.233350828096 -1.69346 0.0129296625084 11:64360260:G:C 289.003 0.233350828096 EHBP1L1 0.0000 0.0002 0.0000 0.0000 biochemistry_Urate_v2 11:65414344:C:G 11 65414344 G C 0.00349031 0.714753 43.4577 4.3E-11 -0.119822 20.2 SIPA1 missense lost rs144822931 0.158626894626 45.9524 0.150015233124 0.0504309 15.7346014452 rs12363578 1382.83 0.00039852935424 SIPA1 0.0001 0.0000 0.0002 0.0000 biochemistry_Urate_v2 11:65429206:C:T 11 65429206 T C 1.18629e-05 0.612905 31.7424 1.8E-08 -1.91909 24.2 RELA missense lost 11:65347766:T:C 1.05372939664 33.4479 1.0 -2.01302 0.0223133513394 11:64366298:C:T 1090.22 0.000277588921 RELA 0.0002 0.0000 0.0000 0.0008 biochemistry_Urate_v2 11:65561574:C:T 11 65561574 T C 0.00995805 0.905052 56.1764 6.6E-14 0.074231 22.5 OVOL1 missense lost rs117624356 0.36604705462 165.283 0.124412103841 -0.0493138 8.76411394016 rs12363578 1382.83 0.00014384883969 OVOL1 0.0016 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:65647350:TGCCTCCTG:T 11 65647350 T TGCCTCCTG 0.00391677 0.959788 40.3346 2.1E-10 -0.0962287 25.0 CTSW frameshift lost 11:64367152:G:A 0.779372115369 507.039 0.061998510025 -1.1141 0.553835384099 11:65557116:T:TG 748.69 0.000739024225 N/A N/A N/A N/A N/A biochemistry_Urate_v2 11:66062910:G:A 11 66062910 A G 1.72833e-05 0.926312 32.4835 1.2E-08 -1.35954 22.3 TMEM151A missense lost 11:64359252:T:C 0.992139839222 1056.97 0.030491096689 -1.56805 0.000503706493986 11:64359252:T:C 1056.97 0.030491096689 TMEM151A 0.0002 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:67050693:G:C 11 67050693 C G 2.72498e-05 0.540604 79.0204 6.1E-19 -2.10927 24.8 ADRBK1 missense lost 11:64368239:C:A 0.345959400877 282.218 0.096867847696 -1.60138 13.4013169614 rs775952762 289.971 0.073613999761 ADRBK1 0.0001 0.0000 0.0000 0.0000 biochemistry_Urate_v2 11:67378946:A:G 11 67378946 G A 0.000105892 0.970599 52.5373 4.2E-13 -0.666423 22.7 NDUFV1 missense lost 11:64396226_T_C 0.633931667496 57.9583 0.574638286401 0.667703 2.18214461877 rs642803 553.259 0.00011955016921 NDUFV1 0.9946 0.0000 0.0020 0.0000 biochemistry_Urate_v2 11:69518449:C:T 11 69518449 T C 5.99738e-05 0.683532 36.4424 1.6E-09 -0.93636 22.9 FGF19 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A FGF19 0.0007 0.0000 0.0000 0.0000 biochemistry_Urate_v2 13:45970147:A:G 13 45970147 G A 0.00632226 0.912642 32.806 1.0E-08 0.0727233 25.5 SLC25A30 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SLC25A30 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 15:48500263:G:A 15 48500263 A G 0.0053052 0.852815 30.9685 2.6E-08 0.0820401 31 SLC12A1 missense won 15:51096622_TG_T 0.000130535263159 31.7394 0.00012736476736 0.0108285 30.2648996843 rs60211045 35.3436 0.00010058485264 SLC12A1 0.0003 0.0000 0.0000 0.0000 biochemistry_Urate_v2 16:69727480:A:G 16 69727480 G A 0.00636227 0.948307 33.4086 7.5E-09 -0.0702771 25.5 NFAT5 missense lost rs555195650 0.103105290164 41.6895 0.082625202916 0.173101 15.3981921364 rs12149228 164.001 0.00128395372329 NFAT5 0.0002 0.0000 0.0001 0.0000 biochemistry_Urate_v2 17:41063408:C:T 17 41063408 T C 0.000368482 0.927043 38.5081 5.5E-10 0.307842 35 G6PC stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A G6PC 0.0535 0.0000 0.0001 0.0000 biochemistry_Urate_v2 17:74307782:CTAGTCACACAGTGATGGA:C 17 74307782 C CTAGTCACACAGTGATGGA 0.000437718 0.922516 45.7296 1.4E-11 0.323442 23.6 PRPSAP1 splice_acceptor won rs193220 0.000430668945723 90.1262 0.00021851934976 0.0196406 43.8512813442 rs193220 90.1262 0.00021851934976 N/A N/A N/A N/A N/A biochemistry_Urate_v2 19:49969006:C:G 19 49969006 G C 0.00105636 0.760556 348.603 8.5E-78 0.613134 24.0 ALDH16A1 missense won N/A N/A N/A N/A N/A N/A rs554048939 125.164 0.248537146225 CTD-3148I10.9 0.1002 0.0000 0.0000 0.0000 biochemistry_Urate_v2 1:117127525:G:A 1 117127525 A G 2.76354e-05 0.636433 33.6314 6.7E-09 -1.29673 25.6 IGSF3 missense lost rs188455012 0.0438267888941 279.513 0.00527330130625 0.4177 21.0239908751 rs188455012 279.513 0.00527330130625 IGSF3 0.0000 0.0000 0.0035 0.0000 biochemistry_Urate_v2 1:120463017:C:T 1 120463017 T C 0.000130515 0.554562 86.2625 1.6E-20 -1.03677 33 NOTCH2 missense won rs188455012 0.105937295739 279.513 0.032694064225 0.4177 39.2474616567 1:120539936:C:T 503.018 0.00387151506225 NOTCH2 0.0105 0.0021 0.0000 0.0000 biochemistry_Urate_v2 1:145761188:G:GA 1 145761188 GA G 7.2971e-05 0.819091 40.0323 2.5E-10 -0.76356 35 PDZK1 frameshift won rs11585527 0.0032096321194 156.105 0.00082309314816 0.0477853 35.6248399134 rs11585527 156.105 0.00082309314816 N/A N/A N/A N/A N/A biochemistry_Urate_v2 1:147380121:G:C 1 147380121 C G 0.000284773 0.873704 73.3311 1.1E-17 -0.510839 24.6 GJA8 missense won 1:145507646:C:T 0.0127418071638 176.37 0.00529778723881 -0.07142 57.7102982713 rs1471633 655.045 0.00011438088601 GJA8 0.0001 0.0000 0.0002 0.0000 biochemistry_Urate_v2 1:151804213:G:A 1 151804213 A G 0.00341894 0.949492 41.7197 1.1E-10 -0.103518 36 RORC stop_gained won rs61817697 0.00813434831806 51.5975 0.00657711268036 0.0143859 34.5336111764 rs776280174 94.3682 0.00027919736464 RORC 0.0001 0.0000 0.0000 0.0145 biochemistry_Urate_v2 2:121991702:T:C 2 121991702 C T 0.00377842 0.898127 32.3612 1.3E-08 0.0901914 22.6 TFCP2L1 missense lost 2:121306440:G:A 0.00181602454729 249.156 0.00023587123561 0.0306986 29.6618340443 2:121306440:G:A 249.156 0.00023587123561 TFCP2L1 0.0137 0.0000 0.0000 0.0000 biochemistry_Urate_v2 2:227917083:G:C 2 227917083 C G 0.00073145 0.830851 53.7521 2.3E-13 0.275447 36 COL4A4 stop_gained won rs2943655 0.000783471086236 58.5775 0.00071893160641 -0.0143642 50.7851111527 rs2943654 87.6647 0.00026056739241 COL4A4 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:8376719:G:A 4 8376719 A G 0.00313648 0.9228 31.552 1.9E-08 -0.100166 24.5 ACOX3 missense lost rs184717641 1.00347543009 602.347 0.052563815824 0.554052 9.51109056e-05 rs58656183 29427.5 0.00022320957604 ACOX3 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:9783915:C:T 4 9783915 T C 0.00967642 0.982332 37.1929 1.1E-09 0.0528348 25.5 DRD5 missense lost 4:10118350:C:A 0.998574340603 20966.4 0.001771399744 -0.348245 1.89121697341e-05 rs58656183 29427.5 0.00302075548996 DRD5 0.0115 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:9784459:C:T 4 9784459 T C 0.000535985 0.912659 32.7589 1.0E-08 -0.23739 22.4 DRD5 missense lost rs11732007 0.999644509443 18338.3 0.00178573011241 0.306586 1.03514850616e-06 rs58656183 29427.5 0.00064759561441 DRD5 0.0014 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:9784658:C:A 4 9784658 A C 0.00356262 0.852161 56.2332 6.4E-14 -0.128668 39 DRD5 stop_gained lost rs527499547 0.997496498802 67.0782 0.836224289209 0.152232 8.82211172458e-05 rs58656183 29427.5 0.00716078133796 DRD5 0.0001 0.0000 0.0013 0.0000 biochemistry_Urate_v2 4:9922013:T:C 4 9922013 C T 8.15028e-05 0.92134 108.477 2.1E-25 -1.12306 22.8 SLC2A9 missense won rs539216377 0.0996826901708 118.066 0.091586732689 0.324328 50.7923351019 rs58656183 29427.5 0.00023554882576 SLC2A9 0.0000 0.0000 0.0192 0.0308 biochemistry_Urate_v2 4:9943611:A:G 4 9943611 G A 5.69161e-05 0.590078 46.6854 8.3E-12 -1.09905 23.8 SLC2A9 missense won rs558289474 0.00246817301086 951.343 0.00012112103025 1.04389 42.1618999462 rs558289474 951.343 0.00012112103025 SLC2A9 0.0095 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:9987317:G:A 4 9987317 A G 0.000151882 0.671341 45.7389 1.4E-11 -0.602325 25.1 SLC2A9 missense lost rs78483961 0.091191164421 664.467 0.00627718690369 0.204358 22.2855320097 rs10805346 18201.6 0.00013445793936 SLC2A9 0.0000 0.0000 0.0000 0.0005 biochemistry_Urate_v2 4:9987355:G:A 4 9987355 A G 3.72566e-05 0.825254 40.5637 1.9E-10 -1.04136 24.0 SLC2A9 missense won rs7377953 0.00792254686004 546.229 0.00058833898249 0.213909 33.6640242331 rs758508737 1610.45 0.00011691448129 SLC2A9 0.0025 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:10020693:C:T 4 10020693 T C 3.25357e-05 0.822121 56.4195 5.9E-14 -1.41366 40 SLC2A9 stop_gained won 4:9670630_CAAAA_C 0.00653739424015 776.911 0.00047474744769 -0.130233 47.6648346164 4:9670630_CAAAA_C 776.911 0.00047474744769 SLC2A9 0.0009 0.0025 0.0000 0.0000 biochemistry_Urate_v2 4:10105567:A:G 4 10105567 G A 0.00436501 0.981956 42.419 7.4E-11 -0.0896119 22.7 WDR1 missense lost rs4333184 1.00024649961 346.658 0.122395722201 0.0989827 6.44287000978e-07 rs58656183 29427.5 0.010050463504 WDR1 0.0000 0.0000 0.0029 0.0000 biochemistry_Urate_v2 4:10445623:A:T 4 10445623 T A 0.000169641 0.741503 53.0768 3.2E-13 -0.608383 25.4 ZNF518B missense lost 4:9916133:A:G 0.31820162118 2865.85 0.00589323370276 -0.352435 10.085354455 rs58656183 29427.5 0.00029587096081 ZNF518B 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:10447327:G:A 4 10447327 A G 0.000198236 0.944856 52.5324 4.2E-13 -0.486761 23.1 ZNF518B missense lost rs764480318 1.00296751552 53.9978 0.97574884 0.501568 0.000115480745428 rs58656183 29427.5 0.00048284349169 ZNF518B 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:10502935:C:T 4 10502935 T C 0.000727988 0.96228 105.644 8.8E-25 -0.35239 32 CLNK missense lost rs147639097 0.859467994593 156.714 0.579384335929 0.349633 0.56182117563 rs58656183 29427.5 0.00170768950564 CLNK 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:40428091:C:T 4 40428091 T C 0.00601194 0.956024 48.699 3.0E-12 0.0805118 29.7 RBM47 missense won N/A N/A N/A N/A N/A N/A rs278981 30.5503 0.017344626601 RBM47 0.0028 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:88537312:C:A 4 88537312 A C 0.00565407 0.901758 74.2559 6.9E-18 0.11473 20.3 DSPP missense lost 4:89020934:G:A 1.02155255539 3098.66 0.024480357444 0.170603 0.00853150825482 rs141471965 5214.35 0.017755296001 DSPP 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 4:88902888:G:A 4 88902888 A G 0.000495773 0.583275 30.3102 3.7E-08 0.301598 24.6 SPP1 missense lost rs142578439 0.347436701051 1828.02 0.00576081 -0.200777 5.10913194746 rs141471965 5214.35 0.00193508490816 SPP1 0.0002 0.0000 0.0001 0.0000 biochemistry_Urate_v2 4:89013496:C:T 4 89013496 T C 0.00482433 0.971028 101.035 9.0E-24 0.130793 21.5 ABCG2 missense won 4:88976790_CT_C 0.0923103575136 771.619 0.012087023481 -0.0667142 48.9674174999 rs2622609 2500.07 0.002310628761 ABCG2 0.0001 0.0206 0.0007 0.0000 biochemistry_Urate_v2 4:89018670:C:T 4 89018670 T C 0.00182097 0.896457 66.1127 4.3E-16 0.184992 22.2 ABCG2 missense won rs2622621 0.0802976527738 1937.14 0.00274048062016 -0.0855378 33.9528939717 rs2622609 2500.07 0.00159011930169 ABCG2 0.0002 0.0000 0.1255 0.0000 biochemistry_Urate_v2 5:72469485:T:A 5 72469485 A T 7.84138e-05 0.766208 62.1628 3.2E-15 -0.970142 25.4 TMEM174 missense won N/A N/A N/A N/A N/A N/A rs10050744 48.0557 0.00012790252836 TMEM174 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 6:28121032:A:C 6 28121032 C A 0.00258566 0.949455 30.1566 4.0E-08 0.110107 23.6 ZKSCAN8 missense lost rs546323487 0.972419076004 33.4189 0.877493068516 -0.125163 0.00581556668486 rs2328895 1830.82 0.00119117477956 ZKSCAN8 0.0000 0.0000 0.0000 0.0000 biochemistry_Urate_v2 6:43018765:TCTC:T 6 43018765 T TCTC 0.00553011 0.938514 44.688 2.3E-11 0.0933374 20.9 CUL7 inframe_deletion lost rs11758941 0.0600632279501 70.7264 0.037950546481 -0.0276377 25.4680138624 rs1317983 430.442 0.00018387902404 N/A N/A N/A N/A N/A biochemistry_Urate_v2 6:43267663:G:A 6 43267663 A G 0.000915944 0.927902 31.4098 2.1E-08 0.183963 25.6 SLC22A7 missense lost 6:43018765:TCTC:T 0.000980723279389 44.688 0.00068931977401 0.0933374 29.4733142112 rs548611999 57.3957 0.00013047807529 SLC22A7 0.0020 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_Urea_v2 13:96230248:GAT:G 13 96230248 G GAT 5.27821e-05 0.724996 31.2849 2.2E-08 0.958228 35 CLDN10 frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A biochemistry_Urea_v2 16:69727480:A:G 16 69727480 G A 0.00635903 0.948307 36.9196 1.2E-09 -0.077801 25.5 NFAT5 missense lost rs190148352 1.00841986694 37.8597 0.983379639025 0.0783907 0.000651605659918 rs4783710 82.1628 0.00442762483216 NFAT5 0.0002 0.0000 0.0001 0.0000 biochemistry_Urea_v2 4:40428091:C:T 4 40428091 T C 0.0060175 0.956024 88.8051 4.4E-21 0.126517 29.7 RBM47 missense won rs34193645 0.000328357090689 89.3568 0.00032632977316 -0.0201887 85.6158517564 rs768804723 90.7843 0.00031345286116 RBM47 0.0028 0.0000 0.0000 0.0000 biochemistry_Urea_v2 9:140127344:C:T 9 140127344 T C 0.000331435 0.901798 30.3918 3.5E-08 0.333734 25.2 SLC34A3 missense lost 9:140130643:GCTC:G 1.0175277542 30.9245 1.0 0.338217 0.00231402290013 9:140130643:GCTC:G 30.9245 1.0 SLC34A3 0.0006 0.0000 0.0111 0.0000 biochemistry_Urea_v2 9:140127675:C:T 9 140127675 T C 0.00128361 0.640597 39.3597 3.5E-10 0.229049 21.8 SLC34A3 missense won N/A N/A N/A N/A N/A N/A 9:140113861_C_T 30.4006 0.00157398660225 SLC34A3 0.0026 0.0004 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss biochemistry_VitaminD_v2 11:14666364:T:C 11 14666364 C T 0.00237516 0.993265 262.804 4.2E-59 -0.35068 27.1 PDE3B missense lost rs190953036 0.998391180796 265.341 0.988845281649 0.35165 0.000170190778343 11:14900931:G:A 3639.2 0.084508234209 PDE3B 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 11:14913645:G:A 11 14913645 A G 0.00168982 0.939433 142.837 6.4E-33 0.31296 24.1 CYP2R1 missense won rs150070397 0.00575256683978 147.381 0.00557520568929 -0.0372859 121.991541232 11:14903636:T:C 984.684 0.00053874123664 CYP2R1 0.0000 0.0000 0.0003 0.0000 biochemistry_VitaminD_v2 11:15261991:A:G 11 15261991 G A 0.00159397 0.855588 160.956 7.0E-37 -0.352549 34 INSC splice_acceptor lost rs576806617 0.963436473658 1427.52 0.1086295681 0.397195 0.0548017119926 11:14900931:G:A 3639.2 0.031639515625 INSC 0.1772 0.9967 0.0000 0.0000 biochemistry_VitaminD_v2 12:96371731:C:T 12 96371731 T C 0.00640644 0.904878 91.7386 9.9E-22 0.128574 23.2 HAL missense lost rs61939239 0.871470896278 93.2685 0.857176002244 -0.135629 0.405373177009 rs2270318 359.677 0.00801721461321 HAL 0.0000 0.0000 0.0000 0.0001 biochemistry_VitaminD_v2 12:96371767:A:G 12 96371767 G A 0.00133296 0.899212 58.2552 2.3E-14 0.222847 25.7 HAL missense won N/A N/A N/A N/A N/A N/A 12:96374672:T:C 57.9877 0.00037487542689 HAL 0.0073 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 12:96379884:C:T 12 96379884 T C 0.00486865 0.888878 30.1233 4.1E-08 0.0891163 32 HAL missense lost 12:96422755_AG_A 0.876406063761 37.0673 0.712224596356 -0.114864 0.12274727725 rs2270318 359.677 0.006193532601 HAL 0.0125 0.0000 0.0000 0.0115 biochemistry_VitaminD_v2 19:11943225:C:T 19 11943225 T C 0.00477091 0.967301 33.5959 6.8E-09 0.0905358 35 ZNF440 stop_gained won 19:11890133_CAA_C 0.00321283003593 35.337 0.00305452971684 0.012395 29.8952836227 rs34732395 37.8823 0.00162804987081 ZNF440 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 1:151735493:C:T 1 151735493 T C 0.00383438 0.941922 47.7059 5.0E-12 0.123138 24.3 MRPL9 missense lost 1:152285076:CACTG:C 0.8149143784 437.57 0.0888457249 0.152766 0.451403492159 1:152285076:CACTG:C 437.57 0.0888457249 OAZ3 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 1:152192456:G:T 1 152192456 T G 0.0021834 0.665993 32.49 1.2E-08 0.151631 21.0 HRNR missense lost 1:152285861:G:A 0.639766396743 352.811 0.058915425625 0.130166 1.30149830833 1:152285861:G:A 352.811 0.058915425625 HRNR 0.0000 0.0000 0.0005 0.0000 biochemistry_VitaminD_v2 1:152277622:G:T 1 152277622 T G 0.00418741 0.910017 45.1397 1.8E-11 0.114782 43 FLG stop_gained won rs12756875 0.00991456151646 114.362 0.00391336573761 0.0228079 36.5979497384 rs12756875 114.362 0.00391336573761 FLG 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 1:152280023:G:A 1 152280023 A G 0.00469098 0.883463 58.7482 1.8E-14 0.119252 41 FLG stop_gained won rs471144 0.0833137584316 111.574 0.043868045809 -0.0401699 29.7284281757 1:152440910:T:C 190.68 0.009576775321 FLG 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 2:21228891:CA:C 2 21228891 C CA 0.00015218 0.642863 31.954 1.6E-08 0.59588 25.3 APOB frameshift won 2:21232804:G:A 0.000157817103822 38.4975 0.00013099260304 -0.0129106 31.1561968634 rs952275 38.6122 0.00013010139844 N/A N/A N/A N/A N/A biochemistry_VitaminD_v2 3:52022837:C:T 3 52022837 T C 0.00393897 0.906022 32.2773 1.3E-08 0.0985172 25.5 ABHD14A-ACY1 missense won rs772585020 0.00111039108702 35.9253 0.00099763749316 -0.0124723 30.1620177522 3:49710514_CCGGG_C 48.4302 0.00031561654336 ACY1 0.0000 0.0000 0.0000 0.0000 biochemistry_VitaminD_v2 4:72631234:G:T 4 72631234 T G 0.00010311 0.792367 31.5577 1.9E-08 -0.630495 23.4 GC missense lost rs114289627 0.033320780586 4538.37 0.00023169710656 0.16826 21.0881543585 rs114289627 4538.37 0.00023169710656 GC 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_BASOPHIL_COUNT_v2 12:51695899:T:A 12 51695899 A T 7.96506e-05 0.757361 34.7581 3.7E-09 0.749648 32 BIN2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A BIN2 0.0119 0.0956 0.0000 0.0000 blood_BASOPHIL_COUNT_v2 17:56277684:C:T 17 56277684 T C 0.00329863 0.956261 81.2379 2.0E-19 0.15476 21.9 EPX missense won rs35527389 0.00146271172687 84.1237 0.00141253450569 -0.0181179 75.142773319 17:57926391_GT_G 91.644 0.00098124936001 EPX 0.0001 0.0000 0.0011 0.0000 blood_BASOPHIL_COUNT_v2 17:56350196:G:A 17 56350196 A G 0.00350206 0.944163 81.234 2.0E-19 0.150757 32 MPO missense lost 17:56277684:C:T 0.900811277126 81.2379 0.900768031744 0.15476 0.210372703241 17:57926391_GT_G 91.644 0.00097471962025 MPO 0.0077 0.0000 0.0000 0.0000 blood_BASOPHIL_COUNT_v2 17:72759559:C:G 17 72759559 G C 0.0013104 0.923027 31.5853 1.9E-08 0.152323 24.1 SLC9A3R1 missense won N/A N/A N/A N/A N/A N/A rs749780 30.8255 0.00032404680169 SLC9A3R1 0.0002 0.0000 0.0000 0.0000 blood_BASOPHIL_COUNT_v2 1:212553243:AG:A 1 212553243 A AG 0.00324164 0.949499 34.9512 3.4E-09 0.104087 34 TMEM206 frameshift lost rs147973555 0.0315134771679 38.0197 0.028970082436 -0.0209552 23.6435348364 1:212455849_TTTTTC_T 138.797 0.00064710201924 N/A N/A N/A N/A N/A blood_BASOPHIL_COUNT_v2 2:218999982:G:A 2 218999982 A G 0.00287467 0.93086 46.9654 7.2E-12 -0.134091 22.6 CXCR2 missense lost rs16858768 1.10231902307 54.5335 0.949340384281 0.141928 0.117009086805 rs16858768 54.5335 0.949340384281 CXCR2 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_EOSINOPHIL_COUNT_v2 11:57155238:A:G 11 57155238 G A 2.37686e-05 0.872697 39.0409 4.2E-10 -1.40845 23.2 PRG2 missense lost 11:57116222:C:T 1.02209990036 39.9037 1.0 -1.40949 0.00471499045619 11:57116222:C:T 39.9037 1.0 PRG2 0.0000 0.0000 0.0067 0.0000 blood_EOSINOPHIL_COUNT_v2 11:116701354:G:A 11 116701354 A G 0.00223805 0.92045 46.3925 9.7E-12 0.150338 31 APOC3 splice_donor won 11:116623213_TA_T 0.000562162876905 97.9184 0.00026634566401 -0.0274547 44.2186501845 11:116623213_TA_T 97.9184 0.00026634566401 APOC3 0.0001 0.0000 0.1104 0.8914 blood_EOSINOPHIL_COUNT_v2 12:111856181:G:A 12 111856181 A G 0.00105854 0.940356 36.9039 1.2E-09 0.177889 22.1 SH2B3 missense lost rs565349424 0.0193293678706 1144.96 0.00062301657609 0.0670029 27.3557234659 rs565349424 1144.96 0.00062301657609 SH2B3 0.0012 0.0000 0.0181 0.0000 blood_EOSINOPHIL_COUNT_v2 12:112167753:G:A 12 112167753 A G 0.00553289 0.971607 40.2718 2.2E-10 -0.0870932 25.1 ACAD10 missense lost rs118151981 1.00940471006 42.4925 0.956652223396 0.0909285 0.000886332819014 rs7137828 2546.5 0.00482251080249 ACAD10 0.0002 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 14:23587838:G:T 14 23587838 T G 0.00817624 0.900526 74.5547 5.9E-18 -0.0922664 24.5 CEBPE missense won N/A N/A N/A N/A N/A N/A rs6572998 46.7229 0.020755012356 CEBPE 0.0002 0.0000 0.0000 0.0005 blood_EOSINOPHIL_COUNT_v2 16:11367446:A:G 16 11367446 G A 0.00927974 0.921768 35.2896 2.8E-09 0.0616858 24.7 PRM3 missense lost rs72775521 0.935936727391 50.3562 0.655903994641 -0.0680907 0.0374164659084 rs62026377 576.294 0.00228937368676 PRM3 0.0000 0.0000 0.0010 0.0000 blood_EOSINOPHIL_COUNT_v2 16:31091390:C:T 16 31091390 T C 0.00865511 0.752541 35.5284 2.5E-09 0.0736092 23.3 ZNF646 missense lost rs8047664 0.185383030958 46.8034 0.140724017424 0.0328298 11.5204544685 rs7201518 183.067 0.00260775678244 ZNF646 0.0001 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 16:50335074:C:A 16 50335074 A C 0.00588639 0.942193 36.1203 1.9E-09 0.0733412 25.0 ADCY7 missense lost rs138425259 0.38377822931 38.1759 0.363113502921 -0.0669096 5.22955089377 rs7500154 52.1006 0.00042882954724 ADCY7 0.0000 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 16:85696635:A:T 16 85696635 T A 0.00714374 0.961994 72.2224 1.9E-17 0.103007 26.1 GSE1 missense won rs731707 0.00182512305199 77.7879 0.00169454075904 -0.0184599 66.1833221781 16:85967187_TAA_T 97.6391 0.00085690267441 GSE1 0.0000 0.0007 0.0009 0.0000 blood_EOSINOPHIL_COUNT_v2 17:4542349:T:C 17 4542349 C T 0.00280091 0.931039 105.449 9.7E-25 -0.201229 27.5 ALOX15 missense won rs7220870 0.000677550751375 109.115 0.00065478668544 -0.0244904 100.030813222 rs7220870 109.115 0.00065478668544 ALOX15 0.0000 0.0000 0.0022 0.0000 blood_EOSINOPHIL_COUNT_v2 17:56274420:T:C 17 56274420 C T 0.00825593 0.898725 59.9841 9.6E-15 0.0832015 25.9 EPX missense won rs4047777 0.00112310090993 74.2371 0.00090747345049 0.0183023 56.0310101721 rs4047777 74.2371 0.00090747345049 EPX 0.0000 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 17:56280445:A:G 17 56280445 G A 8.04934e-05 0.96129 150.627 1.3E-34 -1.37696 29.5 EPX missense won N/A N/A N/A N/A N/A N/A rs563074356 84.343 0.54243225 EPX 0.0002 0.0005 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 17:56281589:G:C 17 56281589 C G 0.000261098 0.885418 32.7294 1.1E-08 -0.333308 33 EPX missense won rs759385603 0.00150291870311 42.0438 0.00116996150209 -0.0180378 30.2409158965 rs4047777 74.2371 0.00054404629504 EPX 0.0000 0.0000 0.0001 0.0000 blood_EOSINOPHIL_COUNT_v2 19:15568281:CGCGCCCGCAGCGCT:C 19 15568281 C CGCGCCCGCAGCGCT 0.00440794 0.972007 45.5253 1.5E-11 -0.0928871 25.6 RASAL3 frameshift won rs10402655 0.00101644029516 310.011 0.00014926486276 0.0398282 42.6687294048 rs116862583 344.934 0.00010851180561 N/A N/A N/A N/A N/A blood_EOSINOPHIL_COUNT_v2 22:17586757:T:C 22 17586757 C T 0.00582585 0.901863 100.351 1.3E-23 -0.139288 25.2 IL17RA missense won N/A N/A N/A N/A N/A N/A rs9606618 79.6493 0.746698189689 IL17RA 0.0000 0.0000 0.0003 0.0000 blood_EOSINOPHIL_COUNT_v2 22:17588658:G:A 22 17588658 A G 0.00103447 0.87878 64.9379 7.7E-16 0.272454 22.4 IL17RA missense won N/A N/A N/A N/A N/A N/A rs181404 47.3829 0.000140446201 IL17RA 0.0053 0.0000 0.0579 0.2601 blood_EOSINOPHIL_COUNT_v2 22:37333972:GC:G 22 37333972 G GC 0.000593319 0.887617 145.945 1.3E-33 -0.498012 25.8 CSF2RB frameshift won N/A N/A N/A N/A N/A N/A rs228951 107.595 0.000112678225 N/A N/A N/A N/A N/A blood_EOSINOPHIL_COUNT_v2 2:214012467:T:C 2 214012467 C T 0.00368769 0.912779 43.7348 3.8E-11 0.113997 24.8 IKZF2 missense won rs57884895 0.021763774125 116.578 0.00816478502464 0.0241738 31.7826375448 2:213824045:A:G 738.228 0.00083295154881 IKZF2 0.0004 0.0000 0.0000 0.0033 blood_EOSINOPHIL_COUNT_v2 2:242756317:G:A 2 242756317 A G 0.00842152 0.873206 36.0045 2.0E-09 -0.0670322 21.3 NEU4 missense lost rs192070055 0.638749444693 37.524 0.612883871161 0.0808248 1.4514639252 rs34290285 486.045 0.00648841527049 NEU4 0.0000 0.0000 0.0002 0.0000 blood_EOSINOPHIL_COUNT_v2 3:3144388:C:T 3 3144388 T C 0.00390233 0.882498 57.293 3.8E-14 0.123396 25.3 IL5RA missense lost 3:3150821_TTTTTCCCCC_T 0.119923894549 75.3399 0.091197356121 -0.0480262 24.4826340491 rs17878498 235.551 0.00970398367744 IL5RA 0.0000 0.0000 0.0000 0.0018 blood_EOSINOPHIL_COUNT_v2 3:46307313:A:G 3 46307313 G A 0.00113779 0.98161 67.4978 2.1E-16 0.2388 24.7 CCR3 missense won 3:48873909_TA_T 0.000373295937185 112.642 0.00022368791844 -0.0232621 64.9147644971 rs577655384 122.422 0.00013982353009 CCR3 0.0001 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 3:128634098:CAG:C 3 128634098 C CAG 0.00636233 0.986622 33.1174 8.7E-09 -0.0724278 27.3 RP11-723O4.6 frameshift lost rs9844706 0.971223374795 837.539 0.038403457024 -0.0893646 0.00695653955182 rs6782812 1656.5 0.023867778064 N/A N/A N/A N/A N/A blood_EOSINOPHIL_COUNT_v2 6:31083945:C:T 6 31083945 T C 0.00521263 0.999338 30.3301 3.6E-08 -0.068245 25.7 CDSN missense lost rs186072506 1.00144785181 30.4206 0.998468586756 0.0684844 1.58835601829e-05 6:31379115:G:A 219.035 0.00070221820036 PSORS1C1 0.0000 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 6:31779728:C:G 6 31779728 G C 0.0038981 0.997931 29.8303 4.7E-08 0.0893895 22.9 HSPA1L missense lost rs144882047 1.00253659527 29.9235 0.999414085849 -0.0895837 4.79236287386e-05 6:31379115:G:A 219.035 0.004829138064 HSPA1L 0.0005 0.0006 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 6:32084337:T:A 6 32084337 A T 0.00431172 0.913574 48.6359 3.1E-12 -0.109397 26.1 ATF6B missense lost rs150209214 0.86202922571 49.2123 0.851932692004 0.113336 0.248949931405 6:31379115:G:A 219.035 0.000548309056 ATF6B 0.0060 0.0037 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 6:32729613:T:C 6 32729613 C T 0.00893198 0.996069 31.7856 1.7E-08 -0.059849 22.6 HLA-DQB2 missense lost 6:32734477:C:T 0.997562305315 32.1161 0.987296602384 -0.0598414 4.72779749792e-05 6:31380157_TGCTG_T 188.882 0.00017810770849 HLA-DQB2 0.0018 0.0000 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 6:135239941:T:C 6 135239941 C T 0.00287184 0.97373 32.6239 1.1E-08 0.0952379 22.3 ALDH8A1 missense lost rs75380469 0.126955827673 106.242 0.038984528025 -0.0426948 13.5173411094 rs6920211 385.143 0.00092369189929 ALDH8A1 0.0001 0.0000 0.0022 0.0000 blood_EOSINOPHIL_COUNT_v2 9:5081828:G:C 9 5081828 C G 0.00103932 0.937121 71.126 3.4E-17 0.263135 21.9 JAK2 missense won 9:5103221_CAAAAAAAAAAAAAAAAAAAAA_C 0.00170753986974 104.382 0.00116351938816 0.0210921 65.3692579369 rs10815402 183.749 0.00010202616064 JAK2 0.0001 0.0000 0.0000 0.0001 blood_EOSINOPHIL_COUNT_v2 9:6255967:G:C 9 6255967 C G 0.00453783 0.96263 376.279 8.0E-84 -0.280406 32 IL33 splice_acceptor lost rs149045797 0.996954112541 388.052 0.966707803369 0.278916 0.00087405720691 rs1888909 1855.35 0.00145340125225 IL33 0.0141 0.8408 0.0000 0.0000 blood_EOSINOPHIL_COUNT_v2 9:6328996:G:A 9 6328996 A G 0.00721018 0.969302 34.5587 4.1E-09 0.0639128 23.9 TPD52L3 missense lost rs3939286 1.00526381105 1828.36 0.019000968336 0.0958846 0.000238757606078 rs1888909 1855.35 0.0188293284 TPD52L3 0.0000 0.0000 0.0256 0.0000 blood_EOSINOPHIL_COUNT_v2 9:6554781:C:A 9 6554781 A C 0.00571172 0.932991 48.2022 3.8E-12 0.091099 25.8 GLDC missense lost rs2066362 0.597047302363 1233.62 0.023328896644 -0.0953798 2.49063570254 rs1888909 1855.35 0.010983249601 GLDC 0.0001 0.4165 0.0001 0.0000 blood_EOSINOPHIL_COUNT_v2 9:135863638:C:T 9 135863638 T C 0.00281458 0.901684 37.7166 8.2E-10 -0.119938 22.5 GFI1B missense lost rs114968084 0.0267526785681 38.5561 0.026170179984 0.0361147 26.3875802619 rs74612091 219.326 0.00014801642244 GFI1B 0.0039 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_HEMOGLOBIN_v2 11:5248004:G:A 11 5248004 A G 1.78656e-05 0.609495 42.2053 8.2E-11 -1.92125 42 HBB stop_gained won N/A N/A N/A N/A N/A N/A 11:4920230_C_A 30.6476 0.00182735730576 HBB 0.0001 0.0033 0.0000 0.0000 blood_HEMOGLOBIN_v2 11:10508903:G:T 11 10508903 T G 0.00892313 0.937752 53.5828 2.5E-13 -0.0765387 26.6 AMPD3 missense won rs11042678 0.0045656189911 151.524 0.00161452079721 0.0240382 46.5863271831 rs368417629 357.883 0.000138909796 AMPD3 0.0000 0.0000 0.0002 0.0000 blood_HEMOGLOBIN_v2 12:111885295:G:A 12 111885295 A G 0.000493057 0.861631 35.5162 2.5E-09 0.288677 32 SH2B3 missense won 12:110738448_CT_C 0.00288172806879 73.9336 0.00138432364225 -0.0271507 31.8054059567 12:112850727_CAAAT_C 511.555 0.00019660246225 SH2B3 0.0001 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 12:111885310:G:A 12 111885310 A G 0.00200624 0.885884 65.2335 6.7E-16 0.190337 32 SH2B3 missense lost rs570074821 1.00201944695 68.8471 0.949426128225 -0.187984 6.64411897716e-05 rs565349424 651.48 0.00101904600625 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_HEMOGLOBIN_v2 16:2086421:C:T 16 2086421 T C 0.00678892 0.956889 75.2507 4.1E-18 -0.103761 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A 16:2225673:C:A 43.518 0.568804064481 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 16:88782050:G:A 16 88782050 A G 0.00995627 0.908822 95.0338 1.9E-22 0.0988621 24.7 PIEZO1 missense won rs4782405 0.0157845139902 103.854 0.014443953489 0.0208319 72.6544465284 rs747494137 208.717 0.001907680329 PIEZO1 0.0001 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 16:88782205:G:C 16 88782205 C G 0.00144203 0.954236 103.779 2.3E-24 0.272681 23.3 PIEZO1 missense lost rs562212325 1.00296419541 105.704 0.9846989824 -0.269322 0.000227625125907 rs2968478 507.806 0.00167525671401 PIEZO1 0.0331 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 16:88793155:C:T 16 88793155 T C 0.00493167 0.958994 41.6401 1.1E-10 -0.0927855 22.4 PIEZO1 missense lost rs144326867 0.936348008094 45.6739 0.853652188489 0.096859 0.0435752334952 rs2968478 507.806 0.002707329024 PIEZO1 0.0014 0.0000 0.0046 0.0015 blood_HEMOGLOBIN_v2 16:88798919:G:T 16 88798919 T G 0.00143076 0.936239 102.976 3.4E-24 0.275425 22.4 PIEZO1 missense lost 16:88782205:G:C 0.996239573578 103.779 0.988531074001 0.272681 0.000364727019746 rs2968478 507.806 0.001736305561 PIEZO1 0.0076 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 16:88801621:G:A 16 88801621 A G 0.001102 0.909541 36.1943 1.8E-09 -0.187418 29.5 PIEZO1 missense lost rs747494137 0.0201372428767 208.717 0.00349206537969 0.0343638 26.650794582 rs2968478 507.806 0.00058946012944 PIEZO1 0.0822 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 16:88871972:G:A 16 88871972 A G 0.00517943 0.961028 30.6121 3.2E-08 -0.0774938 23.3 CDT1 missense lost rs138680888 0.585183885679 33.263 0.538547564164 0.0610042 1.69093987884 rs2968478 507.806 0.00368737988644 CDT1 0.0001 0.0000 0.0027 0.0000 blood_HEMOGLOBIN_v2 19:12995833:T:TC 19 12995833 TC T 0.000209694 0.842305 55.7775 8.1E-14 -0.530391 35 KLF1 frameshift won N/A N/A N/A N/A N/A N/A 19:12995834:C:CC 48.1528 0.874975030801 N/A N/A N/A N/A N/A blood_HEMOGLOBIN_v2 19:41307024:G:A 19 41307024 A G 0.000969058 0.935897 64.3908 1.0E-15 0.269798 24.7 EGLN2 missense won rs2561566 0.00612465025902 76.7625 0.00513754932289 -0.0272185 54.7067044705 rs764772129 140.903 0.000216266436 RAB4B-EGLN2 0.0002 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 19:41510282:A:G 19 41510282 G A 0.00572961 0.906639 59.2913 1.4E-14 -0.102473 23.6 CYP2B6 missense lost rs184088518 0.78744445912 297.308 0.1570378384 0.115217 0.751998244481 rs184088518 297.308 0.1570378384 CYP2B6 0.0001 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 19:50017538:G:C 19 50017538 C G 0.00823006 0.955029 52.6527 4.0E-13 0.0800999 22.6 FCGRT missense won 19:50016759:C:T 0.00154425835814 79.7797 0.00101917370025 -0.0244416 48.595817509 19:50016759:C:T 79.7797 0.00101917370025 FCGRT 0.0108 0.0000 0.0006 0.0000 blood_HEMOGLOBIN_v2 1:155206037:G:A 1 155206037 A G 0.00742601 0.877117 47.1668 6.5E-12 -0.079213 21.8 GBA missense lost rs528163074 0.660248337117 94.3958 0.329906640625 0.091602 1.65720566323 1:155178782:T:A 251.917 0.00971007247609 GBA 0.0000 0.0000 0.0000 0.0021 blood_HEMOGLOBIN_v2 1:155261636:C:T 1 155261636 T C 0.00105961 0.864591 58.8752 1.7E-14 -0.250661 32 PKLR missense won 1:155178782:T:A 0.00554357760034 251.917 0.00129558243364 -0.0314367 50.4344490306 1:155178782:T:A 251.917 0.00129558243364 PKLR 0.0418 0.0000 0.0003 0.0000 blood_HEMOGLOBIN_v2 1:155261649:C:T 1 155261649 T C 0.00634279 0.971679 38.0214 7.0E-10 0.0769331 20.8 PKLR missense lost rs71628645 0.626406685917 38.7547 0.614554084225 -0.0639819 1.65353256168 1:155178782:T:A 251.917 0.00414823588624 PKLR 0.0001 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 1:155261709:G:A 1 155261709 A G 0.00256429 0.899559 64.7541 8.5E-16 -0.163325 33 PKLR missense won 1:155136016_TAC_T 0.0024970503367 94.3341 0.00171405936144 -0.0190292 58.4442054305 1:155161794:C:T 97.1684 0.00015885073296 PKLR 0.0762 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 1:156018299:C:T 1 156018299 T C 0.00912336 0.978484 31.124 2.4E-08 0.0582487 21.6 UBQLN4 missense lost rs185901501 0.96619568164 32.8735 0.914775560721 -0.0627299 0.00904513672998 1:155178782:T:A 251.917 0.00301943656036 UBQLN4 0.0000 0.0000 0.0000 0.0020 blood_HEMOGLOBIN_v2 20:56140439:G:A 20 56140439 A G 0.00255246 0.876177 30.1325 4.0E-08 -0.120803 26.4 PCK1 missense lost rs6015028 0.0263210650375 61.7506 0.012843915561 -0.0214474 21.1483656651 rs55852563 104.821 0.00316289260816 PCK1 0.0859 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 21:45745940:A:G 21 45745940 G A 0.00151335 0.933432 33.2272 8.2E-09 -0.153232 22.7 PFKL missense lost 21:45746102:T:C 0.167666249717 43.2316 0.128865922441 -0.0607913 11.5871506869 21:45746102:T:C 43.2316 0.128865922441 PFKL 0.0001 0.0000 0.0157 0.0021 blood_HEMOGLOBIN_v2 22:37469593:C:T 22 37469593 T C 0.0002399 0.930634 57.4154 3.5E-14 -0.506973 24.6 TMPRSS6 missense lost rs143562710 0.947591302884 63.412 0.857981670529 0.582872 0.0404935582634 rs877908 1427.07 0.00016626813025 TMPRSS6 0.0000 0.0000 0.0073 0.0820 blood_HEMOGLOBIN_v2 2:174130918:G:A 2 174130918 A G 1.29612e-05 0.850899 30.2676 3.8E-08 -1.60061 28.2 MLTK missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A AC013461.1 0.0000 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 3:49713546:A:C 3 49713546 C A 6.63863e-05 0.66279 33.3149 7.8E-09 -0.865285 27.1 APEH missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A APEH 0.0036 0.0000 0.0003 0.0000 blood_HEMOGLOBIN_v2 3:70014091:G:A 3 70014091 A G 0.00411526 0.961313 42.2373 8.1E-11 -0.0954535 31 MITF missense lost rs190948281 0.892625525585 44.0801 0.855308679241 0.101545 0.128751839872 3:69870063_CGT_C 125.672 0.00214882310916 MITF 0.0001 0.0000 0.0001 0.0000 blood_HEMOGLOBIN_v2 5:1212453:G:A 5 1212453 A G 0.00444502 0.972121 32.1945 1.4E-08 -0.0799533 22.5 SLC6A19 missense lost rs117617134 0.238896424551 37.0155 0.207781900561 0.0518183 8.41421888225 5:433952:C:T 49.5496 0.00011695557316 SLC6A19 0.0054 0.0035 0.0000 0.0000 blood_HEMOGLOBIN_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00186581 0.936787 35.6861 2.3E-09 0.127384 35 GMPR frameshift won rs71535075 0.00309190279058 106.634 0.00103473518929 0.0206727 31.8277952648 rs71535075 106.634 0.00103473518929 N/A N/A N/A N/A N/A blood_HEMOGLOBIN_v2 7:98992084:C:T 7 98992084 T C 0.00366433 0.96362 33.9643 5.6E-09 -0.0928707 24.8 ARPC1B missense lost rs545779631 0.823212410453 89.0749 0.3138912676 0.148467 0.291798732368 rs7778978 250.115 0.00026879930401 ARPC1B 0.0000 0.1764 0.0000 0.0000 blood_HEMOGLOBIN_v2 7:99160084:A:G 7 99160084 G A 0.00231543 0.93011 41.3705 1.3E-10 -0.129282 21.4 ZNF655 missense lost rs149823406 0.561590796985 144.497 0.160787366289 0.129113 2.59821459354 rs7778978 250.115 0.00072335716209 N/A N/A N/A N/A N/A blood_HEMOGLOBIN_v2 7:100174951:G:A 7 100174951 A G 0.00098592 0.867982 50.3034 1.3E-12 0.230071 32 LRCH4 missense lost rs532276263 0.841860688648 69.0965 0.612888568384 -0.21834 0.342131327935 rs56261104 359.287 0.00044809692489 LRCH4 0.0001 0.0000 0.0137 0.0000 blood_HEMOGLOBIN_v2 7:100225847:C:T 7 100225847 T C 0.00515336 0.994125 193.235 6.3E-44 0.185053 21.6 NONE N/A lost 7:100239422:G:A 0.988015427223 195.513 0.976503665124 0.183209 0.0069804770801 rs56261104 359.287 0.00269152402401 TFR2 0.0014 0.0000 0.5241 0.4540 blood_HEMOGLOBIN_v2 7:100226902:C:T 7 100226902 T C 0.00378258 0.881336 90.8245 1.6E-21 0.156 22.1 TFR2 missense won rs773492323 0.0158438200843 103.813 0.013861530225 0.0258613 69.3989410318 rs56261104 359.287 0.00162580723369 TFR2 0.0002 0.0000 0.0001 0.0478 blood_HEMOGLOBIN_v2 7:100228655:G:T 7 100228655 T G 0.00603374 0.923732 59.9922 9.5E-15 0.0989528 23.2 TFR2 missense won rs6975957 0.035464962415 88.126 0.0241429444 0.025116 39.5241868809 rs56261104 359.287 0.00231307131136 TFR2 0.0000 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 7:100319633:G:A 7 100319633 A G 0.00534214 0.826534 429.476 2.1E-95 -0.303283 23.9 EPO missense won N/A N/A N/A N/A N/A N/A 7:100275444:G:A 425.453 0.974060433025 EPO 0.0020 0.0000 0.0001 0.1020 blood_HEMOGLOBIN_v2 9:32418353:C:T 9 32418353 T C 0.00128116 0.934964 59.7493 1.1E-14 0.220643 22.6 ACO1 missense won rs10813816 0.0030900201554 79.7034 0.00231641989264 -0.0183419 53.2912443714 rs12985 85.6484 0.00208400467081 ACO1 0.1715 0.1105 0.0000 0.0000 blood_HEMOGLOBIN_v2 9:32418473:A:G 9 32418473 G A 0.00146547 0.885165 35.3947 2.7E-09 -0.156915 26.2 ACO1 missense won rs1133071 0.00385156610787 56.7993 0.002400118081 0.0157918 31.1377649935 rs12985 85.6484 0.00059774382144 ACO1 0.0032 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 9:114886569:C:T 9 114886569 T C 0.00317988 0.888348 42.1713 8.4E-11 0.122667 25.3 SUSD1 missense won rs7849537 0.00136869481113 73.5227 0.00078505875721 0.0200402 39.1086913024 rs66478924 73.647 0.00078255027081 SUSD1 0.0001 0.0000 0.0000 0.0000 blood_HEMOGLOBIN_v2 9:140127675:C:T 9 140127675 T C 0.00130541 0.640597 29.8864 4.6E-08 0.177395 21.8 SLC34A3 missense lost 9:139848278:T:C 0.000813602789156 30.4044 0.00079974143209 0.0104871 28.2057728522 9:139440845:A:G 33.0526 0.00057021141681 SLC34A3 0.0026 0.0004 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 10:46246238:G:A 10 46246238 A G 0.00885459 0.935932 31.5773 1.9E-08 0.0521199 23.7 FAM21C missense lost 10:45941405:C:T 1.00003165472 53.5367 0.589843968169 0.05434 7.91015790964e-09 10:45953767:A:G 437.178 0.016782684304 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 11:10508903:G:T 11 10508903 T G 0.0089317 0.937752 102.123 5.2E-24 -0.103055 26.6 AMPD3 missense won rs16906056 0.000147017929642 116.685 0.00012867045489 0.0226466 99.6615117512 rs17337866 117.564 0.000125260864 AMPD3 0.0000 0.0000 0.0002 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 11:14865399:C:T 11 14865399 T C 0.00106863 0.906863 56.4814 5.7E-14 -0.226025 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs81569 54.8778 0.00012350988225 PDE3B 0.1111 0.0139 0.0003 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 11:63974966:G:A 11 63974966 A G 0.00879718 0.984109 89.3125 3.4E-21 -0.100785 32 FERMT3 missense won 11:65408937:C:T 0.00543760510582 129.314 0.00375555706276 -0.0312608 76.6263174033 rs2306363 184.312 0.00235096977424 FERMT3 0.0018 0.0000 0.0004 0.0059 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00201619 0.885884 55.5149 9.3E-14 0.171358 32 SH2B3 missense lost rs555346412 1.01087554924 65.8288 0.852493969636 -0.207925 0.00163267576592 rs28551113 836.351 0.000117614025 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 12:112673047:T:A 12 112673047 A T 0.00690531 0.996032 51.8898 5.9E-13 -0.0816412 20.7 HECTD4 missense lost rs112791109 1.00159132242 55.4033 0.938073605764 0.0843048 3.28241149257e-05 12:112007756:T:C 1162.61 0.00667557629764 HECTD4 0.0173 0.0039 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 14:65236330:C:T 14 65236330 T C 0.00309451 0.975067 31.4932 2.0E-08 0.0967119 29.1 SPTB missense lost rs188596757 0.0980111506412 32.6439 0.09455625 -0.0440621 14.8609009437 rs11627485 103.63 0.00199541783401 SPTB 0.0000 0.0000 0.0000 0.0004 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:765861:G:A 16 765861 A G 0.00259951 0.945039 30.5031 3.3E-08 0.109572 23.7 METRN missense lost rs117498884 1.32142886677 51.1243 0.788425012489 -0.131298 0.682063824584 16:277399:G:A 194.475 0.093004871089 METRN 0.1253 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:2086421:C:T 16 2086421 T C 0.00680668 0.956889 59.0939 1.5E-14 -0.0933263 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A rs34673494 42.468 0.0492928804 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:88782050:G:A 16 88782050 A G 0.00994594 0.908822 105.717 8.5E-25 0.105639 24.7 PIEZO1 missense won rs74035509 0.0032386508811 110.876 0.00308795821636 -0.0365755 94.0268521121 rs4782371 126.758 0.00255760809984 PIEZO1 0.0001 0.0000 0.0001 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:88782205:G:C 16 88782205 C G 0.00143206 0.954236 170.689 5.2E-39 0.338672 23.3 PIEZO1 missense lost 16:88781091:G:C 1.0016111173 170.964 1.0 0.331536 0.00011067517664 rs562212325 174.199 0.984310031376 PIEZO1 0.0331 0.0000 0.0001 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:88786073:G:A 16 88786073 A G 3.22525e-05 0.839812 58.1067 2.5E-14 1.35229 32 PIEZO1 missense won rs772054169 0.000527793984044 68.8806 0.00044523954049 -0.0474205 55.4675087577 rs55911767 95.5093 0.00010259258944 PIEZO1 0.0081 0.0000 0.0002 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:88798288:C:G 16 88798288 G C 0.000191409 0.875973 57.0637 4.2E-14 0.535623 25.8 PIEZO1 missense won rs62068684 0.00061759045857 65.3231 0.00053950281984 -0.0252088 54.2627200559 rs77440982 79.7806 0.00015839481025 PIEZO1 0.0241 0.0000 0.0004 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 16:88798919:G:T 16 88798919 T G 0.00142015 0.936239 164.442 1.2E-37 0.336503 22.4 PIEZO1 missense lost 16:88781091:G:C 1.01540166439 170.964 0.976665733696 0.331536 0.009677491394 rs562212325 174.199 0.981859028544 PIEZO1 0.0076 0.0000 0.0001 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 17:33884124:C:T 17 33884124 T C 0.00194395 0.925583 33.6858 6.5E-09 0.121009 23.6 SLFN14 missense lost rs551616134 0.0240507555539 55.7634 0.014528686225 -0.0365638 24.0477750444 rs78427228 175.594 0.000219691684 SLFN14 0.0334 0.0000 0.0002 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 17:74382590:G:A 17 74382590 A G 0.000315604 0.965802 31.602 1.9E-08 -0.281014 34 SPHK1 splice_donor lost rs1713399 0.0065900506756 217.452 0.00095772299841 0.0319605 26.6794132327 rs570223913 350.683 0.00028374728704 SPHK1 0.0012 0.0000 0.5465 0.9904 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 17:74383107:CG:C 17 74383107 C CG 0.00361838 0.973727 352.231 1.4E-78 -0.302551 35 SPHK1 frameshift won N/A N/A N/A N/A N/A N/A 17:74383109:T:C 352.231 1.0 N/A N/A N/A N/A N/A blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 18:21057210:G:A 18 21057210 A G 0.00510979 0.967763 188.441 7.0E-43 0.18514 31 RIOK3 missense won N/A N/A N/A N/A N/A N/A rs183907952 128.783 0.685539288729 RIOK3 0.0081 0.0000 0.0002 0.0379 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 18:21057228:C:T 18 21057228 T C 0.00577429 0.910028 244.99 3.2E-55 0.197782 24.2 RIOK3 missense lost rs139563497 1.0009880325 256.808 0.954923748804 -0.201214 5.97607941972e-05 rs139563497 256.808 0.954923748804 RIOK3 0.0003 0.0000 0.0034 0.0231 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00977777 0.967311 112.586 2.7E-26 -0.105046 26.0 S1PR2 missense won rs10409243 0.0151264887139 260.319 0.00654209204224 0.0325126 86.5951736176 rs34797640 2088.68 0.000208918116 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 19:17476153:T:G 19 17476153 G T 0.00371708 0.914963 63.5483 1.6E-15 -0.131067 21.9 PLVAP missense won rs112613803 0.00894534667575 64.5664 0.00880429409344 0.0278382 52.0959851179 rs140594952 166.036 0.00103888248489 PLVAP 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 19:18054468:C:T 19 18054468 T C 0.00054706 0.856325 33.9177 5.7E-09 0.270161 27.6 CCDC124 missense won rs59450344 0.00061391429064 43.0543 0.00048363486889 0.012961 32.2577449214 rs59450344 43.0543 0.00048363486889 CCDC124 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 19:40964064:G:A 19 40964064 A G 0.00675869 0.872551 118.501 1.3E-27 0.132579 32 BLVRB missense won N/A N/A N/A N/A N/A N/A rs556857937 76.9297 0.635038453449 BLVRB 0.0000 0.0000 0.0546 0.0985 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:154956373:A:G 1 154956373 G A 0.000434056 0.910445 37.0437 1.2E-09 0.290432 23.2 FLAD1 missense lost rs559184111 0.907987116036 102.75 0.327349901025 -0.412798 0.0822354241927 1:155261709:G:A 255.61 0.087084600201 N/A N/A N/A N/A N/A blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:155260382:C:T 1 155260382 T C 0.00241873 0.84936 30.7407 2.9E-08 0.106532 24.3 PKLR missense lost rs572135153 0.989484301416 34.312 0.886495688521 -0.112325 0.000854323853189 rs535494646 65.9479 0.00112398597081 PKLR 0.0004 0.0000 0.0775 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:155261709:G:A 1 155261709 A G 0.00255572 0.899559 255.61 1.6E-57 0.299595 33 PKLR missense won N/A N/A N/A N/A N/A N/A rs180864404 227.645 0.753670532164 PKLR 0.0762 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:155264120:C:G 1 155264120 G C 3.06936e-05 0.811592 33.7889 6.1E-09 1.12238 27.1 PKLR missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PKLR 0.0003 0.0000 0.0024 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:155271095:G:A 1 155271095 A G 0.000212942 0.975162 35.7366 2.3E-09 -0.361207 26.9 PKLR missense won rs777458851 0.000187493150492 52.1005 0.00012860467216 0.014318 34.7646311465 1:155867257_CAA_C 57.5885 0.00010793963236 PKLR 0.0000 0.0000 0.0001 0.0045 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:158583604:C:A 1 158583604 A C 0.000801537 0.972715 104.594 1.5E-24 0.347564 27.8 SPTA1 missense won rs145746722 0.00307797444078 319.003 0.00100919947041 0.0359836 93.3102929166 rs2022003 975.033 0.00028862951881 SPTA1 0.0001 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 1:158613207:C:A 1 158613207 A C 0.000409091 0.860242 38.5063 5.5E-10 0.304195 25.2 SPTA1 missense lost rs186270716 0.121952426971 87.6363 0.053584379289 -0.121336 16.3081371002 rs2022003 975.033 0.00018975338001 SPTA1 0.0017 0.0320 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 20:33872191:A:G 20 33872191 G A 0.000336331 0.861504 53.1951 3.0E-13 -0.396767 26.6 EIF6 missense won 20:33422769_CA_C 0.000340616385405 68.0678 0.00026619227716 -0.0161574 51.2497033544 20:34008850_CAA_C 69.2583 0.000189007504 EIF6 0.0000 0.0000 0.0025 0.0033 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:24245713:C:G 2 24245713 G C 0.00488652 0.972585 157.89 3.3E-36 -0.173172 26.0 MFSD2B missense won 2:24242812:C:T 0.257937512294 171.152 0.237950791204 -0.0898513 38.2388319099 2:24210076_GATAA_G 611.423 0.030391646224 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:54135468:T:C 2 54135468 C T 0.000660548 0.949563 30.5344 3.3E-08 -0.207023 23.5 PSME4 missense lost rs531961406 0.978476509313 31.5621 0.946616135364 0.198023 0.00357492356183 rs2692522 90.4545 0.000358042084 PSME4 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:99993019:A:G 2 99993019 G A 0.00754937 0.933772 62.3388 2.9E-15 0.0898972 27.3 EIF5B missense lost rs139550249 0.995872489379 65.1063 0.953540532036 -0.10398 0.000266055666869 rs144338437 65.1467 0.962362962001 EIF5B 0.0000 0.0000 0.0001 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:219892500:G:A 2 219892500 A G 0.00241802 0.814238 62.8981 2.2E-15 0.174895 24.4 CCDC108 missense lost 2:219894092:C:T 1.01850932034 66.1892 0.967866375204 0.178732 0.00533785589711 2:220165527:C:T 273.254 0.097820694169 CCDC108 0.0329 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:220078006:C:T 2 220078006 T C 0.0073072 0.891319 77.1018 1.6E-18 0.105682 25.5 ABCB6 missense lost 2:220115512:T:C 1.05187913194 83.6277 0.969795587524 0.106424 0.050575195739 rs114969635 173.816 0.00168985122084 ABCB6 0.0096 0.0000 0.0129 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 2:220082505:G:A 2 220082505 A G 0.00158722 0.909718 32.5435 1.2E-08 0.133386 28.4 ABCB6 missense lost rs35776200 0.00215888119378 127.121 0.00055268248464 -0.0237517 29.5895706626 2:218683154:A:G 240.243 0.00012035845264 ABCB6 0.0000 0.0643 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:48614349:C:T 3 48614349 T C 0.000393274 0.754996 31.4139 2.1E-08 0.300283 31 COL7A1 missense lost 3:50327017:G:A 0.254475187852 34.7313 0.230168698081 0.579921 7.71413903037 3:49721532:G:A 686.858 0.00012942702756 COL7A1 0.0143 0.0000 0.0021 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:48627789:C:A 3 48627789 A C 0.00767819 0.835537 56.4323 5.8E-14 0.0846808 25.0 COL7A1 missense lost 3:50326292:C:T 0.969419906619 103.373 0.529215510784 0.124912 0.013398717369 3:50329826:A:G 2500.41 0.00508871075904 COL7A1 0.0888 0.0536 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:48638472:T:C 3 48638472 C T 0.00381065 0.891745 45.0525 1.9E-11 0.113673 23.1 UQCRC1 missense lost 3:49742204:G:C 0.59901135585 47.5324 0.567759236004 0.131054 2.30195197653 3:50329826:A:G 2500.41 0.00530973085041 UQCRC1 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:48696521:G:A 3 48696521 A G 0.000287352 0.601227 60.7223 6.6E-15 0.492599 25.3 CELSR3 missense lost rs753485559 1.01475655018 74.0968 0.831592614889 -0.440675 0.00328149044086 3:50329826:A:G 2500.41 0.00011282051089 CELSR3 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:49456758:C:T 3 49456758 T C 0.00713784 0.995965 35.2861 2.8E-09 0.0666562 20.4 AMT missense lost 3:49302618_CAAAAAAA_C 0.978555529247 35.64 0.968838615616 -0.069134 0.00410080238182 3:50329826:A:G 2500.41 0.012041550756 AMT 0.0259 0.0000 0.0097 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:49568966:C:T 3 49568966 T C 0.000733641 0.91912 77.7919 1.1E-18 -0.294842 26.8 DAG1 missense lost rs184962666 1.00249018237 88.782 0.878394449529 0.304287 0.000120447132323 3:50329826:A:G 2500.41 0.00030271476169 DAG1 0.0001 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:49689167:G:C 3 49689167 C G 0.000171292 0.59956 78.7653 7.0E-19 0.763657 23.8 BSN missense lost 3:50326729:C:T 0.751878820865 183.63 0.322507002609 0.627668 1.3909869133 3:50329826:A:G 2500.41 0.00025671089284 BSN 0.0001 0.0000 0.0003 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:49728870:A:G 3 49728870 G A 0.00938714 0.98231 41.7 1.1E-10 -0.0639365 24.0 RNF123 missense lost rs146536381 1.0011670712 48.5814 0.859354956196 0.0770909 1.41911454234e-05 3:50329826:A:G 2500.41 0.00297396806281 RNF123 0.0000 0.0847 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50326254:G:A 3 50326254 A G 0.000649713 0.636099 131.898 1.6E-30 0.538821 31 IFRD2 missense lost rs532400834 0.95662652225 188.338 0.669950435025 -0.547067 0.0634164800819 rs4855880 867.341 0.00012585025489 IFRD2 0.0000 0.0000 0.0032 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50326271:C:T 3 50326271 T C 0.00016589 0.626809 31.6004 1.9E-08 0.553542 25.5 IFRD2 missense lost rs149110768 0.0234800008508 34.5642 0.021466645225 -0.507496 22.6580017079 3:50329826:A:G 2500.41 0.00025213628944 IFRD2 0.0001 0.0000 0.0012 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50326292:C:T 3 50326292 T C 0.00609517 0.924251 103.373 2.8E-24 0.124912 33 IFRD2 missense lost rs11716295 0.33149978027 244.933 0.139908165849 -0.0776967 18.6050134381 3:50329826:A:G 2500.41 0.012534593764 IFRD2 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50326729:C:T 3 50326729 T C 0.000534325 0.750212 183.63 7.8E-42 0.627668 26.5 IFRD2 missense won rs11716295 0.0127843024387 244.933 0.00958458622081 -0.0776967 144.452341763 3:50329826:A:G 2500.41 0.00086472459844 IFRD2 0.0045 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50327017:G:A 3 50327017 A G 9.45714e-05 0.918844 34.7313 3.8E-09 0.579921 23.4 IFRD2 missense lost rs146516543 0.017573927119 82.0213 0.00744154670736 -0.0896924 26.1332384209 rs41499647 1293.73 0.00017404997184 IFRD2 0.0153 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50327685:C:T 3 50327685 T C 0.000940294 0.92898 32.9104 9.7E-09 -0.175015 25.1 IFRD2 missense lost rs533201627 0.625275976531 41.321 0.498005433025 0.140146 1.44108386013 3:50329826:A:G 2500.41 0.000434263921 IFRD2 0.0031 0.0026 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:50391167:C:T 3 50391167 T C 0.00375005 0.827988 56.8217 4.8E-14 0.128701 42 CYB561D2 stop_gained lost 3:50326292:C:T 1.14429747693 103.373 0.628993334281 0.124912 0.276190777271 3:50329826:A:G 2500.41 0.00598210980481 XXcos-LUCA11.5 0.0003 0.0000 0.0207 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:51743429:T:G 3 51743429 G T 0.000183127 0.972684 70.8337 3.9E-17 0.620693 24.6 GRM2 missense lost rs553117490 0.978812217463 72.1041 0.961566554025 -0.629918 0.00803505420532 3:50329826:A:G 2500.41 0.00028680438609 GRM2 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:51992175:A:C 3 51992175 C A 0.0049056 0.939708 40.0814 2.4E-10 -0.0806933 20.8 PCBP4 missense lost 3:51399246:T:C 0.818658574918 57.2304 0.573348811204 -0.0915089 0.363278162 3:50329826:A:G 2500.41 0.00164433494016 PCBP4 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 3:52400807:G:T 3 52400807 T G 0.000756253 0.74375 65.5541 5.7E-16 0.316988 23.1 DNAH1 missense lost rs577101520 0.911491059204 73.1343 0.8170171321 -0.2803 0.134401727701 rs4855880 867.341 0.00017507788489 DNAH1 0.0020 0.0000 0.0001 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 5:38917669:T:A 5 38917669 A T 0.00451232 0.968271 60.5729 7.1E-15 0.114978 24.0 OSMR missense won N/A N/A N/A N/A N/A N/A rs144699990 51.0354 0.853005557889 OSMR 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 5:52097259:G:C 5 52097259 C G 0.000114626 0.891273 34.2425 4.9E-09 0.553284 24.7 PELO missense won rs655137 0.00235563474192 290.385 0.00027777888889 -0.038031 30.9992514492 rs535015671 322.288 0.00016046808976 PELO 0.0008 0.0014 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 5:75866423:C:T 5 75866423 T C 0.000663545 0.910187 42.2437 8.1E-11 0.26138 41 IQGAP2 stop_gained won rs10647961 0.0049977683401 86.5826 0.00243841402809 0.0227796 36.4819962584 rs775657371 106.798 0.00141582875625 IQGAP2 0.0904 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 5:75960968:G:C 5 75960968 C G 0.00590259 0.930086 55.7704 8.1E-14 0.0962014 27.7 IQGAP2 missense won rs250721 0.0312326531873 85.918 0.020273488225 0.0225658 37.7999169659 rs10647961 86.5826 0.019516928209 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 6:16286061:C:A 6 16286061 A C 0.00146267 0.923729 135.477 2.6E-31 0.312267 32 GMPR missense won 6:16281187:C:T 0.000507992464077 158.194 0.00043504364929 -0.0265916 129.438873583 6:16281187:C:T 158.194 0.00043504364929 GMPR 0.0661 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00185625 0.936787 161.124 6.4E-37 0.285313 35 GMPR frameshift won N/A N/A N/A N/A N/A N/A 6:16281187:C:T 158.194 0.00055636072129 N/A N/A N/A N/A N/A blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 6:30124811:C:T 6 30124811 T C 0.00867552 0.934131 57.5315 3.3E-14 0.0860346 22.4 TRIM10 missense lost rs114077552 0.540147973319 88.7821 0.350020140625 -0.0698032 4.0417475399 rs116596081 374.295 0.00010725294969 TRIM10 0.0001 0.0266 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 6:49604368:C:T 6 49604368 T C 0.000226712 0.858624 114.901 8.3E-27 0.710384 34 RHAG splice_donor won rs35365087 0.000168242112262 189.623 0.00010194537024 -0.029139 111.939611334 rs35365087 189.623 0.00010194537024 RHAG 0.0004 0.0000 0.3148 0.9729 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 7:6066379:G:T 7 6066379 T G 0.000277904 0.837347 30.5342 3.3E-08 0.329878 31 EIF2AK1 missense lost rs12672853 0.00180181306795 53.8681 0.00102132654724 -0.0182591 27.9969996023 rs28430759 110.306 0.00030595257225 EIF2AK1 0.0000 0.0000 0.0015 0.0067 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 8:41575677:G:A 8 41575677 A G 0.00134602 0.91167 35.472 2.6E-09 0.161878 29.2 ANK1 missense won rs569451 0.00504163936348 514.25 0.00034776282256 0.0485515 30.613493612 rs4737010 880.807 0.00017928406609 ANK1 0.0001 0.0000 0.0000 0.0000 blood_HIGH_LIGHT_SCATTER_RETICULOCYTE_COUNT_v2 8:86242013:A:G 8 86242013 G A 0.00044125 0.810343 67.9358 1.7E-16 0.39883 23.9 CA1 missense won rs35718625 0.00113276672752 85.461 0.00090047406241 -0.0229522 63.4397793133 rs2132589 95.9324 0.00015705603684 CA1 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_IMMATURE_RETICULOCYTE_FRAC_v2 10:46246238:G:A 10 46246238 A G 0.00885108 0.935932 62.9028 2.2E-15 0.0806834 23.7 FAM21C missense lost rs35490739 0.862420492716 87.1095 0.622764035716 -0.0781875 0.320083612305 10:45953767:A:G 539.683 0.016765847289 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 11:63974966:G:A 11 63974966 A G 0.00879538 0.984109 179.876 5.2E-41 -0.146838 32 FERMT3 missense won rs12419109 0.00435942136983 203.844 0.00384684012441 0.0403657 156.907200528 rs2306363 249.562 0.00236297098816 FERMT3 0.0018 0.0000 0.0004 0.0059 blood_IMMATURE_RETICULOCYTE_FRAC_v2 11:65414344:C:G 11 65414344 G C 0.00349399 0.714753 39.6379 3.1E-10 -0.123666 20.2 SIPA1 missense lost rs143961416 0.10389341656 40.2794 0.102238783504 0.0493884 18.2034432765 rs2306363 249.562 0.008502315264 SIPA1 0.0001 0.0000 0.0002 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 16:88782205:G:C 16 88782205 C G 0.00143408 0.954236 30.1843 3.9E-08 0.156228 23.3 PIEZO1 missense lost rs562212325 1.00561678925 30.8365 0.984347732449 -0.153687 0.000237399754331 16:88781091:G:C 31.4897 1.0 PIEZO1 0.0331 0.0000 0.0001 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 17:74383107:CG:C 17 74383107 C CG 0.00361368 0.973727 190.793 2.1E-43 -0.229227 35 SPHK1 frameshift won N/A N/A N/A N/A N/A N/A 17:74383109:T:C 190.793 1.0 N/A N/A N/A N/A N/A blood_IMMATURE_RETICULOCYTE_FRAC_v2 18:21057210:G:A 18 21057210 A G 0.00511276 0.967763 141.003 1.6E-32 0.166269 31 RIOK3 missense won N/A N/A N/A N/A N/A N/A rs183907952 94.3066 0.685555848289 RIOK3 0.0081 0.0000 0.0002 0.0379 blood_IMMATURE_RETICULOCYTE_FRAC_v2 18:21057228:C:T 18 21057228 T C 0.00578387 0.910028 109.998 9.8E-26 0.138054 24.2 RIOK3 missense lost rs140271614 0.94257800933 111.544 0.929513876769 -0.130609 0.0933743762368 rs140271614 111.544 0.929513876769 RIOK3 0.0003 0.0000 0.0034 0.0231 blood_IMMATURE_RETICULOCYTE_FRAC_v2 19:10334725:A:G 19 10334725 G A 0.00977699 0.967311 41.7622 1.0E-10 -0.0669511 26.0 S1PR2 missense won rs10409243 0.0218941570975 139.869 0.00653717526784 0.0239543 30.3177147206 rs34797640 2660.47 0.000206669376 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 19:10812828:C:A 19 10812828 A C 0.00314543 0.95792 31.2724 2.2E-08 0.0973004 25.9 QTRT1 missense lost rs544078050 1.008398564 31.7031 0.994699043716 -0.0974317 0.000549152904933 rs34797640 2660.47 0.00477413284401 QTRT1 0.0194 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 19:40964064:G:A 19 40964064 A G 0.0067582 0.872551 72.9131 1.4E-17 0.107265 32 BLVRB missense won N/A N/A N/A N/A N/A N/A rs556857937 42.5522 0.635293484809 BLVRB 0.0000 0.0000 0.0546 0.0985 blood_IMMATURE_RETICULOCYTE_FRAC_v2 1:45797228:C:T 1 45797228 T C 0.00605478 0.980585 59.0285 1.6E-14 0.101142 34 MUTYH missense lost 1:45810865:G:A 0.198122819896 168.136 0.069556150225 0.0475889 18.1750538319 1:45810865:G:A 168.136 0.069556150225 MUTYH 0.0203 0.0004 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 1:155261709:G:A 1 155261709 A G 0.00256013 0.899559 63.8937 1.3E-15 0.154092 33 PKLR missense won N/A N/A N/A N/A N/A N/A rs180864404 52.6871 0.754401684969 PKLR 0.0762 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 2:24245713:C:G 2 24245713 G C 0.00488975 0.972585 110.881 6.3E-26 -0.147556 26.0 MFSD2B missense lost 2:24242812:C:T 0.339171700961 157.953 0.238094226601 -0.0878282 19.3379468142 rs72781658 515.653 0.030658609216 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 2:54135468:T:C 2 54135468 C T 0.00066104 0.949563 41.203 1.4E-10 -0.246383 23.5 PSME4 missense lost rs531961406 1.00163149554 43.5936 0.946703702169 0.237413 2.7395963085e-05 rs538757190 45.6532 0.538453634436 PSME4 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 2:99993019:A:G 2 99993019 G A 0.0075508 0.933772 31.4763 2.0E-08 0.0662348 27.3 EIF5B missense lost rs144369599 1.00645374476 38.1775 0.8297934649 -0.0739411 0.000326700066026 rs144369599 38.1775 0.8297934649 EIF5B 0.0000 0.0000 0.0001 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:48638472:T:C 3 48638472 C T 0.00380814 0.891745 36.0584 1.9E-09 0.0985879 23.1 UQCRC1 missense lost 3:49742204:G:C 0.672147699211 42.688 0.567760743001 0.120647 1.17029022691 3:50329826:A:G 1506.98 0.00530350975504 UQCRC1 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:48696521:G:A 3 48696521 A G 0.000287418 0.601227 37.9603 7.2E-10 0.414969 25.3 CELSR3 missense lost rs753485559 0.984751241475 45.3479 0.824325989776 -0.364022 0.00222366285398 3:50329826:A:G 1506.98 0.00011266336449 CELSR3 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:49568966:C:T 3 49568966 T C 0.000733711 0.91912 36.1989 1.8E-09 -0.217649 26.8 DAG1 missense lost rs184962666 0.995867504501 41.04 0.878394449529 0.224199 0.000154867010352 3:50329826:A:G 1506.98 0.000302481664 DAG1 0.0001 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:49689167:G:C 3 49689167 C G 0.000171204 0.59956 74.4951 6.1E-18 0.783959 23.8 BSN missense lost 3:50326729:C:T 0.609267602031 141.146 0.321563848356 0.586337 3.58736279326 3:50329826:A:G 1506.98 0.00025639375129 BSN 0.0001 0.0000 0.0003 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:49728870:A:G 3 49728870 G A 0.00938617 0.98231 39.5489 3.2E-10 -0.0676554 24.0 RNF123 missense lost rs144775975 0.995961637969 57.5488 0.684448454596 0.0903004 0.000161570908711 3:50329826:A:G 1506.98 0.00296771084289 RNF123 0.0000 0.0847 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:50326254:G:A 3 50326254 A G 0.00064919 0.636099 62.6895 2.4E-15 0.391921 31 IFRD2 missense lost rs532400834 0.967599415258 90.8098 0.667971117025 -0.40122 0.0167248898426 rs9839427 535.787 0.00019038756361 IFRD2 0.0000 0.0000 0.0032 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:50326729:C:T 3 50326729 T C 0.000534976 0.750212 141.146 1.5E-32 0.586337 26.5 IFRD2 missense won 3:50329826:A:G 0.0092230912401 1506.98 0.00086384851569 -0.0830175 115.337346397 3:50329826:A:G 1506.98 0.00086384851569 IFRD2 0.0045 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 3:51743429:T:G 3 51743429 G T 0.000182947 0.972684 53.038 3.3E-13 0.583036 24.6 GRM2 missense lost rs537639610 0.987012793666 53.3738 0.980803026025 -0.586829 0.00225108865446 3:50329826:A:G 1506.98 0.00028644208516 GRM2 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 5:38917669:T:A 5 38917669 A T 0.00451143 0.968271 48.2159 3.8E-12 0.106514 24.0 OSMR missense won N/A N/A N/A N/A N/A N/A rs144699990 43.7612 0.853133017104 OSMR 0.0000 0.0000 0.0000 0.0000 blood_IMMATURE_RETICULOCYTE_FRAC_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00185781 0.936787 52.1759 5.1E-13 0.164024 35 GMPR frameshift won N/A N/A N/A N/A N/A N/A 6:16281187:C:T 47.7844 0.000559369801 N/A N/A N/A N/A N/A blood_IMMATURE_RETICULOCYTE_FRAC_v2 6:30124811:C:T 6 30124811 T C 0.00867311 0.934131 77.7481 1.2E-18 0.0990314 22.4 TRIM10 missense lost rs114077552 0.384407022052 85.4449 0.349779982084 -0.0713883 11.2264910288 6:30127873:C:T 265.625 0.00053744221584 TRIM10 0.0001 0.0266 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_LYMPHOCYTE_COUNT_v2 10:26792144:G:A 10 26792144 A G 0.0049864 0.936723 41.1892 1.4E-10 0.0899607 22.7 APBB1IP missense won rs702997 0.00080179777131 45.9409 0.00071886725689 0.0180549 38.8895958483 rs6482558 48.3892 0.00016133064256 APBB1IP 0.0011 0.0022 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 11:63974995:C:G 11 63974995 G C 0.0041569 0.958009 37.5853 8.8E-10 0.0965216 21.5 FERMT3 missense won 11:65747057:G:A 0.000152237158646 39.2406 0.00014581528516 0.0132145 36.6635337677 11:65747057:G:A 39.2406 0.00014581528516 FERMT3 0.0000 0.0000 0.0024 0.0016 blood_LYMPHOCYTE_COUNT_v2 11:64136019:G:A 11 64136019 A G 0.00240942 0.896879 33.585 6.8E-09 0.117944 24.4 RPS6KA4 missense lost rs550118485 1.10766412036 45.1409 0.824106286809 -0.141105 0.0924143761548 rs574117315 58.973 0.4629849849 RPS6KA4 0.0003 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00200839 0.885884 41.7203 1.1E-10 0.146024 32 SH2B3 missense won rs565349424 0.0227470515022 926.256 0.00102456967921 0.0599942 30.0846976528 rs565349424 926.256 0.00102456967921 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_LYMPHOCYTE_COUNT_v2 12:112167753:G:A 12 112167753 A G 0.0055204 0.971607 41.1273 1.4E-10 -0.0854329 25.1 ACAD10 missense lost rs147896030 0.998612159656 42.5219 0.965860459524 0.0927845 1.98175857686e-05 rs7137828 1920.18 0.00484449408576 ACAD10 0.0002 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 13:114806502:G:A 13 114806502 A G 0.000333662 0.831243 30.2182 3.9E-08 -0.307726 24.0 RASA3 missense lost rs3118899 0.000319155983604 90.7131 0.000106316721 -0.0199064 29.1481518246 rs3118899 90.7131 0.000106316721 RASA3 0.0000 0.0000 0.0027 0.0011 blood_LYMPHOCYTE_COUNT_v2 16:3598190:C:T 16 3598190 T C 0.00296079 0.970361 32.8513 9.9E-09 0.102799 24.9 NLRC3 missense won rs8047038 0.0017743029143 44.8759 0.00129887439201 -0.0152256 30.1420320203 rs447361 75.553 0.000480398724 NLRC3 0.0001 0.0226 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 16:88788037:G:A 16 88788037 A G 0.000971312 0.953717 42.1214 8.6E-11 -0.207625 31 PIEZO1 missense won 16:88844003:T:C 0.0126123119255 42.6748 0.012448757476 -0.0275272 33.1917985003 rs8052370 87.5937 0.00044215155076 PIEZO1 0.0170 0.0000 0.0118 0.0000 blood_LYMPHOCYTE_COUNT_v2 17:16852187:A:G 17 16852187 G A 0.00696138 0.947032 159.09 1.8E-36 -0.151151 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs12946913 144.294 0.00019078515625 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 17:72759559:C:G 17 72759559 G C 0.00132742 0.923027 50.5684 1.2E-12 0.211625 24.1 SLC9A3R1 missense won rs16978167 0.000593333217562 102.823 0.00029180155684 -0.0245594 48.1348700292 rs16978167 102.823 0.00029180155684 SLC9A3R1 0.0002 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 17:74383107:CG:C 17 74383107 C CG 0.00361769 0.973727 150.625 1.3E-34 0.19733 35 SPHK1 frameshift won N/A N/A N/A N/A N/A N/A 17:74383109:T:C 150.625 1.0 N/A N/A N/A N/A N/A blood_LYMPHOCYTE_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00977916 0.967311 51.4761 7.2E-13 -0.0700205 26.0 S1PR2 missense won 19:10412471_GTT_G 0.0413977348046 328.757 0.00648197281449 0.0368315 32.6599932323 rs11085725 369.852 0.00289973634064 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 19:10464843:G:A 19 10464843 A G 0.00777429 0.919201 68.4552 1.3E-16 0.0925185 33 TYK2 missense won rs11085725 0.0961795920921 369.852 0.017801696929 -0.0412226 32.5793970677 19:10395683:A:G 433.666 0.00406118151076 TYK2 0.0014 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 19:15568123:G:A 19 15568123 A G 0.00918093 0.889539 47.3719 5.9E-12 0.0768773 25.7 RASAL3 missense won rs8101504 0.00169254575516 735.73 0.00010897898449 0.054415 43.5542660299 rs8101504 735.73 0.00010897898449 RASAL3 0.0000 0.0000 0.0456 0.0124 blood_LYMPHOCYTE_COUNT_v2 19:15568281:CGCGCCCGCAGCGCT:C 19 15568281 C CGCGCCCGCAGCGCT 0.00439321 0.972007 69.5072 7.6E-17 -0.120826 25.6 RASAL3 frameshift won rs10405866 0.00156542796069 480.903 0.00022625875561 0.0617972 64.1158357285 rs10405866 480.903 0.00022625875561 N/A N/A N/A N/A N/A blood_LYMPHOCYTE_COUNT_v2 21:46308800:C:T 21 46308800 T C 0.00750429 0.952876 46.5412 9.0E-12 -0.0758299 25.6 ITGB2 missense won N/A N/A N/A N/A N/A N/A rs139711584 44.7176 0.824927145025 ITGB2 0.0019 0.0012 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 22:29091856:AG:A 22 29091856 A AG 0.00250406 0.876417 105.99 7.4E-25 0.211944 35 CHEK2 frameshift won 22:30324160_CT_C 0.00190870961598 262.454 0.00077081748496 0.0333155 96.9311562613 rs2412973 300.423 0.00040160560801 N/A N/A N/A N/A N/A blood_LYMPHOCYTE_COUNT_v2 2:24245713:C:G 2 24245713 G C 0.00489533 0.972585 45.7909 1.3E-11 0.0940735 26.0 MFSD2B missense lost 2:24242812:C:T 0.494005572942 94.9987 0.238118624676 0.0682149 4.04310626321 2:24253661_CAG_C 373.842 0.031867605225 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 2:68615546:A:C 2 68615546 C A 0.00871687 0.982982 110.28 8.5E-26 -0.111548 21.6 PLEK missense won N/A N/A N/A N/A N/A N/A rs141250842 95.5324 0.783734842944 PLEK 0.0013 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 5:68682228:A:G 5 68682228 G A 9.08454e-05 0.898944 32.7165 1.1E-08 -0.615992 24.5 RAD17 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A RAD17 0.0728 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:15501422:G:A 6 15501422 A G 0.00334512 0.895678 33.0557 9.0E-09 0.102565 22.5 JARID2 missense lost rs9396582 0.00376273406947 58.167 0.002138322564 -0.0151186 29.124731913 rs9396582 58.167 0.002138322564 JARID2 0.0000 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:29323245:G:C 6 29323245 C G 0.00831007 0.966596 32.405 1.3E-08 -0.0671443 24.4 OR5V1 missense lost rs147682429 0.563028649295 33.5633 0.543598018681 0.0828174 2.01960757067 6:31449022:C:T 254.173 0.00062336606929 OR5V1 0.0001 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:30520367:C:T 6 30520367 T C 0.00618541 0.993454 54.5396 1.5E-13 0.097122 23.3 GNL1 missense lost rs114141512 1.00480555238 60.6183 0.904045360969 -0.0994524 0.000314120985804 6:31449022:C:T 254.173 0.00835200415449 GNL1 0.0006 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:30610758:G:T 6 30610758 T G 0.00617907 0.989392 54.4703 1.6E-13 0.0970545 22.8 ATAT1 missense lost rs144797308 0.999591692243 86.2208 0.631495640889 -0.111251 2.27072067677e-06 6:31449022:C:T 254.173 0.00831138542224 ATAT1 0.0005 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:31237115:CT:C 6 31237115 C CT 0.00217132 0.713161 48.1241 4.0E-12 -0.166991 23.5 HLA-C frameshift lost rs9469053 0.0576951887624 97.7477 0.028405057444 0.0613672 27.7819819397 6:31540556:T:C 294.14 0.00052503306496 N/A N/A N/A N/A N/A blood_LYMPHOCYTE_COUNT_v2 6:31605016:T:C 6 31605016 C T 0.00829071 0.99288 94.0183 3.1E-22 0.111765 29.9 PRRC2A missense lost rs140666828 0.990358551504 95.6967 0.972988905604 -0.111761 0.00219552404788 6:31449022:C:T 254.173 0.014343415696 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:32008783:C:T 6 32008783 T C 0.0082143 0.900143 50.3446 1.3E-12 -0.0929294 23.8 CYP21A2 missense lost 6:31937552:T:C 0.992833998752 59.6125 0.838479019225 -0.0934878 0.000648644795749 6:31540556:T:C 294.14 0.0020421361 CYP21A2 0.0018 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:32063460:G:A 6 32063460 A G 0.00340841 0.818934 67.3068 2.3E-16 0.156899 24.0 TNXB missense lost 6:32151458:G:A 0.90124368832 88.658 0.684200282896 0.132594 0.172748435249 6:31449022:C:T 254.173 0.00501912737764 TNXB 0.0000 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:32151458:G:A 6 32151458 A G 0.00535436 0.979931 88.658 4.7E-21 0.132594 26.1 AGER missense lost rs138503238 1.00009430008 97.7409 0.907157192704 -0.131142 1.97088630254e-07 6:31449022:C:T 254.173 0.00825148774129 AGER 0.0865 0.0000 0.0047 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:32363893:G:A 6 32363893 A G 0.00887299 0.977753 30.6942 3.0E-08 -0.055367 25.5 BTNL2 missense lost rs17211937 0.999843914385 51.3963 0.597113198361 0.0758936 1.86963134985e-07 rs111940905 254.166 0.00478105868304 BTNL2 0.0001 0.0000 0.0000 0.0000 blood_LYMPHOCYTE_COUNT_v2 6:32609899:C:T 6 32609899 T C 0.00178066 0.539351 31.9547 1.6E-08 -0.177664 27.3 HLA-DQA1 missense lost rs4959031 0.199770794521 181.912 0.035091779584 0.0897408 9.77354533426 rs111940905 254.166 0.00139747373584 HLA-DQA1 0.0010 0.0000 0.0001 0.0000 blood_LYMPHOCYTE_COUNT_v2 8:90983460:G:A 8 90983460 A G 0.00370971 0.958772 67.3774 2.2E-16 0.133846 26.0 NBN missense won N/A N/A N/A N/A N/A N/A rs118026302 66.4536 0.937630065969 NBN 0.0008 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 10:45959729:A:G 10 45959729 G A 0.00261085 0.941163 36.5321 1.5E-09 -0.105703 22.4 MARCH8 missense lost rs191373043 0.978727320264 38.6276 0.925632561604 0.114367 0.00417749217159 rs11239535 746.771 0.00125177978025 MARCH8 0.0221 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 10:46246238:G:A 10 46246238 A G 0.00884461 0.935932 95.1697 1.7E-22 0.0945863 23.7 FAM21C missense lost rs34604216 1.00048812053 693.105 0.137376233449 -0.102198 5.66743943333e-06 rs11239535 746.771 0.018005345856 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 11:19246240:G:A 11 19246240 A G 0.000190073 0.737794 113.791 1.4E-26 0.857106 39 E2F8 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A E2F8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 11:67198887:C:T 11 67198887 T C 0.00405927 0.653001 67.0601 2.6E-16 -0.148784 25.7 RPS6KB2 missense lost rs544129906 0.591640720382 67.7958 0.585220410009 0.158795 3.57276213906 11:67202156:C:T 330.344 0.00326828312721 RPS6KB2 0.0001 0.0015 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 11:93530853:TAAAC:T 11 93530853 T TAAAC 9.76053e-05 0.917373 38.8042 4.7E-10 -0.61668 35 MED17 frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 12:12022496:T:C 12 12022496 C T 0.00924381 0.96914 47.6883 5.0E-12 0.0651186 22.3 ETV6 missense won N/A N/A N/A N/A N/A N/A 12:11793675:C:T 35.1702 0.00030114743296 ETV6 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 13:73319139:G:A 13 73319139 A G 0.00404345 0.9402 99.0158 2.5E-23 -0.150094 28.6 BORA missense won N/A N/A N/A N/A N/A N/A rs191078878 91.6103 0.918244979001 BORA 0.0472 0.1196 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 15:41488231:G:C 15 41488231 C G 0.00849453 0.975227 32.1212 1.4E-08 0.0573412 26.3 EXD1 missense lost rs149888933 1.00060608692 32.7812 0.980460393124 -0.0594554 2.94896765236e-06 15:40308859:G:T 152.14 0.00084020558769 EXD1 0.0445 0.0085 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 15:65472527:C:G 15 65472527 G C 0.00337049 0.953173 48.2974 3.7E-12 0.114162 25.6 CLPX missense won rs35375480 0.00211980059347 400.621 0.00025555539321 -0.0554972 43.9524314391 rs55770518 424.171 0.00022826677225 CLPX 0.0184 0.0015 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:105863:G:A 16 105863 A G 0.000793039 0.505578 45.9026 1.2E-11 -0.29334 22.2 SNRNP25 missense lost 16:722740:C:T 0.415677955303 139.273 0.137002139044 -1.21167 5.79364813206 rs11866877 2067.44 0.00020539475856 SNRNP25 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:138725:T:A 16 138725 A T 0.00205531 0.542685 41.646 1.1E-10 0.177065 28.1 NPRL3 missense lost rs551516676 0.417984584684 73.4448 0.2370131856 -0.151416 5.20366928548 rs11866877 2067.44 0.00110081286225 NPRL3 0.0000 0.0000 0.0039 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:169168:C:T 16 169168 T C 0.000223776 0.697212 274.78 1.0E-61 -1.1722 27.1 NPRL3 missense won 16:216593:T:C 0.0338920163859 643.087 0.014481474921 -0.2889 182.920036785 16:216593:T:C 643.087 0.014481474921 NPRL3 0.0000 0.0000 0.0000 0.0163 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:216367:G:T 16 216367 T G 0.00177463 0.78643 61.6602 4.1E-15 -0.184437 21.0 HBM missense won 16:290304:C:T 0.0161089873294 424.804 0.00233821569601 -0.0383736 47.0015120159 rs556207545 1427.24 0.00019540684944 HBM 0.0005 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:325035:G:A 16 325035 A G 0.00646413 0.903685 46.5951 8.7E-12 0.0782954 23.1 RGS11 missense lost rs113643051 1.01452917415 486.829 0.097102038544 -0.0892884 0.00244131712477 rs11866877 2067.44 0.00141004756036 RGS11 0.0166 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:336730:C:A 16 336730 A C 0.0067141 0.908672 30.4356 3.5E-08 0.0666745 LOW NONE N/A lost rs3760047 1.01335566675 1407.81 0.021907848169 0.0856318 0.00134824027441 rs11866877 2067.44 0.00201954967236 PDIA2 0.0000 0.0000 0.5694 0.0117 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:700712:G:T 16 700712 T G 2.92072e-05 0.719562 43.6341 4.0E-11 -1.2339 LOW NONE N/A lost rs556175248 0.219577777292 60.6758 0.157906095876 0.567498 12.3220621192 rs186066503 233.114 0.039720888601 WDR90 0.0004 0.0000 0.7280 0.1134 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:839668:C:G 16 839668 G C 1.61436e-05 0.915752 33.6721 6.5E-09 -1.35988 23.9 CHTF18 missense won rs545585457 0.000387064732143 37.5677 0.000346927876 0.301529 32.3602061339 rs545585457 37.5677 0.000346927876 CHTF18 0.0000 0.0000 0.0002 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:845148:TC:T 16 845148 T TC 9.10425e-05 0.873403 35.5544 2.5E-09 0.606488 29.3 CHTF18 frameshift lost rs2858934 0.019601694066 944.3 0.00073803502224 -0.100931 26.2956642558 rs556207545 1427.24 0.00025944833476 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:1967915:T:A 16 1967915 A T 0.00016187 0.75619 32.4983 1.2E-08 -0.453533 24.8 HS3ST6 missense lost 16:223539:C:G 1.04427382196 250.798 0.135316565316 -1.28054 0.0155824787763 16:216593:T:C 643.087 0.00015919373584 HS3ST6 0.0010 0.0000 0.0122 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:1967918:C:A 16 1967918 A C 0.00016187 0.75619 32.4983 1.2E-08 -0.453533 26.0 HS3ST6 missense lost 16:1967915:T:A 1.0 32.4983 1.0 -0.453533 0.0 16:216593:T:C 643.087 0.00015919373584 HS3ST6 0.0009 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:2287866:G:A 16 2287866 A G 5.93261e-05 0.91121 42.4824 7.1E-11 -0.755851 40 DNASE1L2 stop_gained won rs3760045 0.000730719074997 82.6577 0.00037555726849 0.0390029 40.2166898619 rs3760045 82.6577 0.00037555726849 DNASE1L2 0.1056 0.0000 0.0002 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:31539522:T:C 16 31539522 C T 0.000421939 0.930923 43.589 4.1E-11 -0.311903 25.1 AHSP missense lost rs574938121 0.786144678254 48.0268 0.713502885481 0.363502 0.560060920883 16:30103160:C:A 416.279 0.00045492197521 AHSP 0.0008 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:67166731:G:A 16 67166731 A G 0.00679954 0.967352 59.5477 1.2E-14 -0.0806025 22.8 C16orf70 missense lost 16:67221080:GC:G 0.972121313309 61.79 0.936843960649 -0.0802424 0.011734583793 rs35158985 203.223 0.00036955833121 C16orf70 0.0001 0.0480 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:67231976:G:A 16 67231976 A G 0.000157343 0.867439 37.8435 7.7E-10 0.496057 24.6 E2F4 missense lost rs141446134 0.910124080743 39.1207 0.880410643204 -0.518311 0.080062101465 rs4783682 72.4899 0.00014157906169 E2F4 0.0118 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 16:88967923:G:A 16 88967923 A G 0.00129537 0.946316 32.8754 9.8E-09 -0.134606 25.2 CBFA2T3 missense lost 16:88947968:T:C 1.01578616368 35.5219 0.940106707281 -0.134313 0.00203215322985 rs12232375 144.674 0.02660161 CBFA2T3 0.0000 0.0000 0.0000 0.0437 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 17:16852187:A:G 17 16852187 G A 0.00696787 0.947032 60.9061 6.0E-15 -0.0880558 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs572423904 45.9003 0.473705957169 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 17:46894356:G:A 17 46894356 A G 0.00247923 0.969958 39.7045 3.0E-10 0.108492 35 TTLL6 stop_gained lost rs780939847 1.03337525183 41.7125 0.983629551961 -0.110636 0.0108760340489 rs575705078 311.475 0.087931227024 TTLL6 0.0006 0.0000 0.4033 0.1612 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 18:67755229:C:T 18 67755229 T C 0.00105848 0.886468 30.1887 3.9E-08 -0.172123 26.5 RTTN missense won N/A N/A N/A N/A N/A N/A rs372511831 30.1061 0.00018460385161 RTTN 0.0009 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 19:4354080:C:T 19 4354080 T C 0.00567257 0.85131 44.274 2.9E-11 -0.0850841 25.7 MPND missense lost rs77887378 0.431624614069 577.074 0.033114900625 0.068693 5.20935550875 rs8887 1620.51 0.00512249392656 MPND 0.0172 0.0007 0.0002 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 19:12825854:T:C 19 12825854 C T 0.00887281 0.918036 30.4107 3.5E-08 -0.0549221 LOW NONE N/A lost 19:12825846:CTTGACCA:C 1.00057874367 30.4283 1.0 -0.0549795 2.545735519e-06 rs11672387 1119.36 0.00239123934009 TNPO2 0.0005 0.0000 0.7186 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 19:12995833:T:TC 19 12995833 TC T 0.00021073 0.842305 404.574 5.6E-90 -1.35863 35 KLF1 frameshift lost 19:12995834:C:CC 0.899296833973 415.82 0.874975030801 -1.32941 1.08085373913 19:12995834:C:CC 415.82 0.874975030801 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 19:12996474:AG:A 19 12996474 A AG 1.33999e-05 0.902814 50.0675 1.5E-12 -1.81189 31 KLF1 frameshift won rs77440950 0.00159560343106 766.444 0.00010423184836 0.0713699 46.1474947908 rs62109862 767.996 0.00010308950089 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 19:19349163:C:T 19 19349163 T C 0.000179735 0.828271 32.0668 1.5E-08 0.361752 29.0 NCAN missense won 19:18440959_CAT_C 0.00101811754285 76.2147 0.000428365809 -0.0356234 30.0530757985 rs748650054 92.3232 0.00032892900496 NCAN 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:43896217:G:A 1 43896217 A G 0.00642381 0.987491 33.1187 8.7E-09 -0.0659748 24.8 SZT2 missense lost 1:43770518:C:G 1.00806273604 39.9853 0.834950027536 -0.0683533 0.00053608374985 1:46441649_CT_C 99.8923 0.00015938305009 SZT2 0.0041 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:47838652:A:G 1 47838652 G A 0.00737468 0.987001 36.0879 1.9E-09 -0.0611591 21.8 CMPK1 missense lost rs77652178 0.999921483715 37.0467 0.974042668096 0.0636971 5.56209185749e-08 rs11211480 282.953 0.00827228449441 CMPK1 0.0015 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:118165603:G:A 1 118165603 A G 0.000570882 0.903197 112.237 3.2E-26 -0.426721 23.4 FAM46C missense won rs826415 0.000577102367958 305.652 0.00021191498329 -0.034237 106.909243433 rs10923397 332.881 0.000108222409 FAM46C 0.0003 0.0000 0.0005 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:118165662:C:T 1 118165662 T C 0.000217567 0.845076 30.3118 3.7E-08 -0.315282 24.1 FAM46C missense lost rs546567145 0.544623619606 31.1272 0.530356801536 0.322039 2.08094252248 rs559362584 99.3656 0.00014479068241 FAM46C 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:226421157:T:G 1 226421157 G T 0.00997235 0.971351 34.7283 3.8E-09 -0.0564708 23.5 LIN9 missense lost rs150477134 1.11889272579 39.784 0.976705264656 0.0601576 0.115930408572 rs7406 57.4467 0.00014279294016 LIN9 0.0011 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 1:240656550:G:C 1 240656550 C G 0.00358626 0.862203 38.4314 5.7E-10 -0.0959966 22.9 GREM2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A GREM2 0.0000 0.0000 0.0032 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 20:35675512:G:A 20 35675512 A G 0.00136029 0.909193 76.9414 1.8E-18 0.227877 29.3 RBL1 missense won N/A N/A N/A N/A N/A N/A rs1885120 66.4778 0.00010069319716 RBL1 0.0006 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 20:35696466:T:A 20 35696466 A T 0.000165981 0.736956 54.4138 1.6E-13 0.592653 23.4 RBL1 missense won rs2145943 0.000151523908354 81.9558 0.00010060290601 -0.016885 53.0824311274 rs2145943 81.9558 0.00010060290601 RBL1 0.0714 0.0000 0.0004 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 22:29091856:AG:A 22 29091856 A AG 0.00250371 0.876417 51.5958 6.8E-13 -0.143139 35 CHEK2 frameshift won rs76317766 0.00979117242818 67.6691 0.00746549568961 0.0333276 41.8901380916 rs5763787 164.7 0.00010255207824 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 22:37469593:C:T 22 37469593 T C 0.000236256 0.930634 103.753 2.3E-24 -0.620277 24.6 TMPRSS6 missense lost rs143562710 0.949711735502 115.308 0.854541243396 0.735129 0.0672985652334 rs877908 4300.75 0.00015779630689 TMPRSS6 0.0000 0.0000 0.0073 0.0820 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 22:37471208:G:A 22 37471208 A G 0.00658719 0.926862 43.8607 3.5E-11 -0.0703127 25.4 TMPRSS6 missense lost rs143210163 0.626527773934 60.1354 0.456967888036 0.0886691 1.90608186267 rs6000550 1487.29 0.00124173778689 TMPRSS6 0.0001 0.0000 0.0252 0.0029 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 2:160714958:C:T 2 160714958 T C 0.00223865 0.964578 31.4737 2.0E-08 -0.116924 36 LY75-CD302 stop_gained lost rs796929846 0.00770167310291 68.2148 0.00355348324321 0.0158621 26.1918881465 rs139012450 103.381 0.00226191555216 LY75 0.0081 0.0024 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 3:133476769:C:T 3 133476769 T C 0.00119096 0.942472 263.118 3.6E-59 0.436218 24.1 TF missense won N/A N/A N/A N/A N/A N/A rs8177258 155.71 0.00054006041664 TF 0.0000 0.0000 0.0010 0.0004 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 4:88053456:G:T 4 88053456 T G 0.000396975 0.851159 44.3824 2.7E-11 -0.323683 24.2 AFF1 missense won 4:87863004_CAAAA_C 0.0086472487652 222.639 0.00172380244969 0.0359331 36.5118950379 rs767653779 255.392 0.00123754093369 AFF1 0.0012 0.0061 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:16286061:C:A 6 16286061 A C 0.00146518 0.923729 239.138 6.1E-54 0.368067 32 GMPR missense won 6:16282518_AG_A 0.00162090607927 865.519 0.00044784717376 0.0577313 220.269999919 6:16281187:C:T 867.369 0.000439112025 GMPR 0.0661 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00186307 0.936787 357.957 7.8E-80 0.395292 35 GMPR frameshift won rs7765828 0.00258674655515 884.481 0.00104687838025 0.0532542 322.471509046 rs2327958 885.196 0.001028420761 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:26157073:A:G 6 26157073 G A 0.00957007 0.979289 71.9617 2.2E-17 -0.0790665 24.7 HIST1H1E missense lost 6:26089164_TGTGAGAAG_T 0.69672200006 72.2503 0.6939389809 0.0874618 1.96631775112 6:26093141:G:A 6684.97 0.00068876328249 HIST1H1E 0.0009 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:26184042:TC:T 6 26184042 T TC 0.00280591 0.930248 38.1007 6.7E-10 0.109155 24.4 HIST1H2BE frameshift lost rs189493943 0.995786977752 89.7545 0.422710626244 -0.127799 0.000169424714908 6:26118537_CTCAAAGATCAGTTTGG_C 4901.04 0.011574101889 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:26234939:C:T 6 26234939 T C 0.000574533 0.6935 45.213 1.8E-11 0.279184 25.2 HIST1H1D missense lost rs79220007 0.487359273627 6620.54 0.00332827455744 -0.290405 4.12056977942 6:26093141:G:A 6684.97 0.00328719902281 HIST1H1D 0.0043 0.0000 0.0132 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:26235041:C:T 6 26235041 T C 0.00472013 0.9635 31.981 1.6E-08 -0.0745352 24.0 HIST1H1D missense lost rs571303647 1.03772947753 34.2198 0.969836948809 0.0793671 0.0111715729141 6:26093141:G:A 6684.97 0.00040811676361 HIST1H1D 0.0012 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:29323245:G:C 6 29323245 C G 0.00830712 0.966596 37.608 8.6E-10 -0.0619597 24.4 OR5V1 missense lost rs143977400 1.0048035658 62.5309 0.6043196644 0.0837874 0.000216424552436 rs13191659 1923.02 0.00056229688384 OR5V1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:30043301:G:C 6 30043301 C G 0.000798416 0.995511 82.4679 1.1E-19 0.269536 26.5 RNF39 missense lost rs756537235 0.999514608164 103.867 0.793590560569 -0.341567 4.85864647086e-06 rs34302671 565.062 0.00526459080625 RNF39 0.0000 0.0000 0.0004 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:30078265:A:G 6 30078265 G A 0.00128421 0.998012 47.6659 5.1E-12 0.162885 21.2 TRIM31 missense lost rs114852065 1.00020596825 47.7177 0.9991201936 -0.163017 5.05479624986e-07 rs34302671 565.062 0.00461688993529 TRIM31 0.0000 0.0000 0.0000 0.0003 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:30080533:G:C 6 30080533 C G 0.00128437 0.999072 47.6465 5.1E-12 0.162815 23.3 TRIM31 missense lost 6:30104972:C:T 1.0000839516 47.6505 1.0 0.162817 8.39480781507e-08 rs34302671 565.062 0.00461688993529 TRIM31 0.0006 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:31605016:T:C 6 31605016 C T 0.00828476 0.99288 34.068 5.3E-09 -0.0615617 29.9 PRRC2A missense lost 6:31599556:A:C 1.00019528096 34.3092 0.993163723776 -0.0617802 3.2476113638e-07 rs114179634 604.455 0.00029899943056 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:31660879:C:T 6 31660879 T C 0.00177564 0.918914 31.993 1.5E-08 0.116728 26.3 ABHD16A missense lost 6:30563922_C_T 1.01355108358 86.4009 0.3753032644 -0.299997 0.00145886560065 rs9261599 316.699 0.00087896832676 XXbac-BPG32J3.20 0.0052 0.0006 0.0002 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:37139030:G:C 6 37139030 C G 0.00330033 0.963439 32.2248 1.4E-08 0.0936691 22.8 PIM1 missense lost rs538849300 0.902913255193 38.5955 0.7538754276 -0.0936974 0.0798627061337 rs35893164 201.127 0.352416760609 PIM1 0.0003 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:135239941:T:C 6 135239941 C T 0.00287025 0.97373 34.6251 4.0E-09 -0.098629 22.3 ALDH8A1 missense lost rs565570162 0.965755601198 37.3223 0.895962581809 0.109928 0.01032865007 6:135418635:C:T 8916.15 0.00099949557904 ALDH8A1 0.0001 0.0000 0.0022 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:135360757:C:G 6 135360757 G C 0.00258208 0.957096 44.5298 2.5E-11 0.11777 22.0 HBS1L missense lost rs6934903 1.00546808817 4869.64 0.00919437430129 -0.156123 0.000331953167917 6:135418635:C:T 8916.15 0.00654995625124 HBS1L 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 6:135732649:T:C 6 135732649 C T 0.00510977 0.910051 46.1439 1.1E-11 0.0840118 21.9 AHI1 missense lost rs137966474 0.972592383308 240.99 0.186228497764 -0.0882963 0.0087863895741 6:135418635:C:T 8916.15 0.003671754025 AHI1 0.0028 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 7:100064620:G:A 7 100064620 A G 0.00698127 0.785537 50.3142 1.3E-12 -0.0882364 24.7 TSC22D4 missense lost rs183662966 0.47471703088 63.7734 0.374529312144 0.107517 4.86652988056 7:100240296:G:A 2253.65 0.00720646490281 TSC22D4 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 7:100218512:C:T 7 100218512 T C 8.83209e-05 0.888009 137.94 7.5E-32 1.18782 31 TFR2 missense won rs2527884 0.000131303695905 154.748 0.00011704210596 0.0219037 134.796863121 rs2527884 154.748 0.00011704210596 TFR2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 7:100224387:C:T 7 100224387 T C 0.000967008 0.853484 148.433 3.8E-34 0.374057 30 TFR2 missense won 7:99702947:G:A 0.0078844950488 228.961 0.00511143493249 0.0441703 123.243198027 rs2406257 957.728 0.00018093209121 TFR2 0.0010 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 7:100225847:C:T 7 100225847 T C 0.00514508 0.994125 166.321 4.7E-38 0.156868 21.6 NONE N/A lost 7:100239422:G:A 0.999505714906 170.266 0.976347538609 0.155537 1.01613047629e-05 7:100240296:G:A 2253.65 0.00313504807225 TFR2 0.0014 0.0000 0.5241 0.4540 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 8:30469817:T:C 8 30469817 C T 0.0066851 0.963237 47.7015 5.0E-12 -0.0759926 24.9 GTF2E2 missense lost rs531670400 1.03690371361 52.1667 0.9481501129 0.0778527 0.0159480403564 8:30279470_CAAAAAAG_C 243.291 0.00225066745744 GTF2E2 0.0000 0.0000 0.0025 0.0035 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 9:5081828:G:C 9 5081828 C G 0.00104632 0.937121 34.3674 4.6E-09 -0.156097 21.9 JAK2 missense lost rs12005199 0.017167971944 525.539 0.00112269224356 0.0461797 25.9513308792 rs35797651 814.626 0.00011165937561 JAK2 0.0001 0.0000 0.0000 0.0001 blood_MEAN_CORPUSCULAR_HEMOGLOBIN_v2 9:135863638:C:T 9 135863638 T C 0.00281395 0.901684 32.073 1.5E-08 0.101215 22.5 GFI1B missense lost rs75856805 0.176344784781 41.1847 0.137330277561 -0.0442065 10.7918030831 9:135864436:C:G 229.368 0.00013614922489 GFI1B 0.0039 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MEAN_CORPUSCULAR_VOL_v2 10:45959729:A:G 10 45959729 G A 0.00261504 0.941163 42.385 7.5E-11 -0.113885 22.4 MARCH8 missense lost rs191373043 0.963780691789 44.122 0.925838462025 0.122167 0.0141581479494 rs11239535 783.926 0.001257624369 MARCH8 0.0221 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 10:46246238:G:A 10 46246238 A G 0.00884569 0.935932 98.395 3.4E-23 0.0938169 23.7 FAM21C missense lost rs12765244 0.985994768999 722.215 0.134332512196 -0.101709 0.0048590446134 rs11239535 783.926 0.0180338041 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 10:101295456:T:G 10 101295456 G T 0.00837384 0.978121 53.3435 2.8E-13 -0.0736793 33 NKX2-3 missense won 10:101322555:A:G 0.0123393432004 230.838 0.002851453201 0.0311184 42.1506548027 10:101322555:A:G 230.838 0.002851453201 NKX2-3 0.0000 0.0000 0.0021 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 11:4132858:A:T 11 4132858 T A 0.00112885 0.968239 38.6948 5.0E-10 -0.16875 25.0 RRM1 missense lost 11:4211111_TG_T 0.901380207843 38.9687 0.895044660624 0.162134 0.0990316901801 rs232044 289.842 0.00149083248769 RRM1 0.0008 0.0000 0.0000 0.0003 blood_MEAN_CORPUSCULAR_VOL_v2 11:19246240:G:A 11 19246240 A G 0.0001897 0.737794 135.274 2.9E-31 0.886165 39 E2F8 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A E2F8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 11:67198887:C:T 11 67198887 T C 0.00406054 0.653001 84.147 4.6E-20 -0.158478 25.7 RPS6KB2 missense won rs553917782 0.109531319233 237.656 0.038781818761 0.0588108 37.6659638914 rs11227793 364.033 0.003284206864 RPS6KB2 0.0001 0.0015 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 12:12022496:T:C 12 12022496 C T 0.00925065 0.96914 48.6609 3.0E-12 0.0649101 22.3 ETV6 missense won N/A N/A N/A N/A N/A N/A rs571926464 30.7959 0.114204119481 ETV6 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 13:73319139:G:A 13 73319139 A G 0.00404252 0.9402 110.562 7.4E-26 -0.155972 28.6 BORA missense won N/A N/A N/A N/A N/A N/A rs191078878 103.624 0.9183963889 BORA 0.0472 0.1196 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 15:65472527:C:G 15 65472527 G C 0.00336773 0.953173 41.4696 1.2E-10 0.100842 25.6 CLPX missense won 15:64356121_AACACAC_A 0.00253122152169 51.5949 0.00203447906704 -0.0138908 37.4017942105 rs55770518 376.42 0.00022759343044 CLPX 0.0184 0.0015 0.0001 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:105863:G:A 16 105863 A G 0.00079477 0.505578 44.2026 3.0E-11 -0.279558 22.2 SNRNP25 missense lost 16:722740:C:T 0.399134368797 127.243 0.138654203769 -1.1366 5.99355116837 16:170328:C:T 1658.97 0.00020361292249 SNRNP25 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:169168:C:T 16 169168 T C 0.000223344 0.697212 189.86 3.4E-43 -0.952881 27.1 NPRL3 missense won 16:216593:T:C 0.0400209486962 526.217 0.014439627225 -0.254378 121.494493325 16:216593:T:C 526.217 0.014439627225 NPRL3 0.0000 0.0000 0.0000 0.0163 blood_MEAN_CORPUSCULAR_VOL_v2 16:216367:G:T 16 216367 T G 0.00177724 0.78643 63.8921 1.3E-15 -0.189996 21.0 HBM missense won 16:290304:C:T 0.0135367160457 370.616 0.00233365320241 -0.0356476 49.8896305755 16:157592_CAA_C 960.083 0.00052727181376 HBM 0.0005 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:700712:G:T 16 700712 T G 2.91577e-05 0.719562 35.7857 2.2E-09 -1.14732 LOW NONE N/A lost rs186066503 0.209274165779 189.842 0.039448712689 0.649646 10.5333167418 rs186066503 189.842 0.039448712689 WDR90 0.0004 0.0000 0.7280 0.1134 blood_MEAN_CORPUSCULAR_VOL_v2 16:845148:TC:T 16 845148 T TC 9.19774e-05 0.873403 34.1578 5.1E-09 0.56521 29.3 CHTF18 frameshift lost 16:836294:G:A 0.757535793036 35.6281 0.726273815089 0.455944 0.574026947376 rs11248914 933.8 0.00010432375321 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_VOL_v2 16:2287866:G:A 16 2287866 A G 5.9181e-05 0.91121 36.7749 1.3E-09 -0.659915 40 DNASE1L2 stop_gained won rs3760045 0.000726575841988 71.2874 0.00037481734404 0.0365451 34.8190796874 16:855717:C:G 93.6878 0.000117896164 DNASE1L2 0.1056 0.0000 0.0002 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:31539522:T:C 16 31539522 C T 0.000421063 0.930923 36.5128 1.5E-09 -0.285123 25.1 AHSP missense lost 16:31471277:G:T 0.997303423167 36.7212 0.991643530969 -0.287093 6.64655942878e-05 16:30103160:C:A 479.379 0.000458687889 AHSP 0.0008 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:67166731:G:A 16 67166731 A G 0.00680056 0.967352 68.6763 1.2E-16 -0.0854676 22.8 C16orf70 missense lost 16:67221080:GC:G 0.958904448018 70.2955 0.936816859449 -0.0847272 0.0296074544459 16:67324265_TAG_T 200.946 0.00010145324176 C16orf70 0.0001 0.0480 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:67210851:G:A 16 67210851 A G 0.000898927 0.955132 37.5202 9.0E-10 -0.181592 33 KIAA0895L missense lost rs536750429 0.977300190854 45.6288 0.803626188304 0.182677 0.00488901379271 rs35158985 130.0 0.00166027726225 KIAA0895L 0.0414 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 16:67231976:G:A 16 67231976 A G 0.000157027 0.867439 51.1713 8.5E-13 0.545925 24.6 E2F4 missense won N/A N/A N/A N/A N/A N/A rs548012760 50.1985 0.871958161369 E2F4 0.0118 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 17:16852187:A:G 17 16852187 G A 0.00697037 0.947032 88.7903 4.4E-21 -0.104987 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs572423904 64.8935 0.473767902864 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 17:46894356:G:A 17 46894356 A G 0.00247901 0.969958 46.8419 7.7E-12 0.122119 35 TTLL6 stop_gained lost rs780939847 1.04039801575 49.5437 0.983661289209 -0.125424 0.0187349375765 rs575705078 385.238 0.0877640625 TTLL6 0.0006 0.0000 0.4033 0.1612 blood_MEAN_CORPUSCULAR_VOL_v2 17:47788784:G:A 17 47788784 A G 0.000375677 0.915052 32.6852 1.1E-08 0.279025 28.3 FAM117A missense won rs35014661 0.000340249288746 76.0731 0.00014618986281 0.0174854 31.4905086888 rs35014661 76.0731 0.00014618986281 FAM117A 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 17:76134198:G:A 17 76134198 A G 0.00211988 0.895334 33.0841 8.8E-09 -0.123769 29.9 TMC8 missense lost rs76944096 0.0331199587623 41.2288 0.026577150625 0.0260703 22.1379662694 rs383603 197.928 0.00056631148729 TMC8 0.0009 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 18:21116700:A:G 18 21116700 G A 0.000819203 0.880176 36.5454 1.5E-09 -0.214889 24.1 NPC1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A NPC1 0.0020 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 19:4354080:C:T 19 4354080 T C 0.00567197 0.85131 63.7993 1.4E-15 -0.103537 25.7 MPND missense lost rs117315514 0.405675681407 69.5691 0.372030463249 0.0810827 8.41016324466 rs8887 1284.39 0.00511731345316 MPND 0.0172 0.0007 0.0002 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 19:12825854:T:C 19 12825854 C T 0.00887308 0.918036 32.8834 9.8E-09 -0.0578782 LOW NONE N/A lost 19:12825846:CTTGACCA:C 1.0007085642 32.9067 1.0 -0.0579244 4.12592485057e-06 rs11672387 986.152 0.00240087260169 TNPO2 0.0005 0.0000 0.7186 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 19:12995833:T:TC 19 12995833 TC T 0.000210273 0.842305 341.974 2.4E-76 -1.22953 35 KLF1 frameshift lost 19:12995834:C:CC 0.914594967849 357.459 0.874975030801 -1.2189 0.651732387411 19:12995834:C:CC 357.459 0.874975030801 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_VOL_v2 19:12996474:AG:A 19 12996474 A AG 1.33711e-05 0.902814 48.1415 4.0E-12 -1.77128 31 KLF1 frameshift won rs77440950 0.00128825327784 596.137 0.00010403388009 0.0627567 44.747705384 rs77440950 596.137 0.00010403388009 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_VOL_v2 1:43896217:G:A 1 43896217 A G 0.00641565 0.987491 38.4515 5.6E-10 -0.0682664 24.8 SZT2 missense lost rs185142956 1.00968293493 38.8931 0.998218793881 0.0687277 0.000896958382317 1:46441649_CT_C 104.683 0.00015907263376 SZT2 0.0041 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 1:47838652:A:G 1 47838652 G A 0.00737685 0.987001 39.6837 3.0E-10 -0.0635385 21.8 CMPK1 missense lost rs78663709 0.997897201806 40.0838 0.9879366025 0.0640515 4.39141352068e-05 1:47691568:GCAGA:G 464.261 0.00823042685089 CMPK1 0.0015 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 1:118165603:G:A 1 118165603 A G 0.000570799 0.903197 80.0942 3.6E-19 -0.348849 23.4 FAM46C missense won rs826415 0.000583022510325 219.219 0.000213014025 -0.0286865 76.2730101902 rs10923397 236.399 0.00010864101361 FAM46C 0.0003 0.0000 0.0005 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 1:226421157:T:G 1 226421157 G T 0.00997054 0.971351 31.5674 1.9E-08 -0.0540158 23.5 LIN9 missense lost rs187386252 0.993072722927 34.4063 0.911133248089 0.0553322 0.00038002494176 rs7406 81.7072 0.00014210308849 LIN9 0.0011 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 20:35675512:G:A 20 35675512 A G 0.00136149 0.909193 106.562 5.6E-25 0.261201 29.3 RBL1 missense won N/A N/A N/A N/A N/A N/A rs182322127 87.5088 0.793918422441 RBL1 0.0006 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 20:35696466:T:A 20 35696466 A T 0.000165832 0.736956 63.3875 1.7E-15 0.621749 23.4 RBL1 missense won rs12480662 0.000247287501941 76.8859 0.00020387270656 -0.0188142 61.4095901861 rs2145943 130.301 0.00010038637249 RBL1 0.0714 0.0000 0.0004 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 22:29091856:AG:A 22 29091856 A AG 0.00250598 0.876417 36.536 1.5E-09 -0.122275 35 CHEK2 frameshift lost rs147563555 0.011388729373 42.4602 0.00979973284096 0.0488185 29.1540016568 rs41177 172.837 0.00028371022969 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_VOL_v2 22:37465286:A:G 22 37465286 G A 0.000233178 0.729973 30.9348 2.7E-08 -0.344506 25.1 TMPRSS6 missense lost rs5756491 0.0201347944028 2968.23 0.000209844196 -0.0965952 22.7785474033 rs5756491 2968.23 0.000209844196 TMPRSS6 0.0004 0.0000 0.0127 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 22:37469593:C:T 22 37469593 T C 0.000236892 0.930634 80.7737 2.5E-19 -0.54156 24.6 TMPRSS6 missense lost rs143562710 0.951702773123 89.8657 0.855415962769 0.638151 0.0482766577333 rs877908 3073.94 0.0001597696 TMPRSS6 0.0000 0.0000 0.0073 0.0820 blood_MEAN_CORPUSCULAR_VOL_v2 22:37471208:G:A 22 37471208 A G 0.00659212 0.926862 50.2588 1.3E-12 -0.0739697 25.4 TMPRSS6 missense lost rs143210163 0.506146563799 55.6645 0.456993576169 0.0831926 4.18489946217 rs6000550 1248.41 0.00124452317284 TMPRSS6 0.0001 0.0000 0.0252 0.0029 blood_MEAN_CORPUSCULAR_VOL_v2 2:24245713:C:G 2 24245713 G C 0.0048998 0.972585 51.7918 6.2E-13 -0.0942843 26.0 MFSD2B missense lost 2:24242812:C:T 0.269060988344 58.4809 0.238285541025 -0.0505949 11.9970114569 rs72796106 202.179 0.023518676164 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 2:27455332:C:T 2 27455332 T C 5.76001e-05 0.952651 30.6345 3.1E-08 0.688385 33 CAD missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CAD 0.0004 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 3:133476769:C:T 3 133476769 T C 0.00119038 0.942472 211.73 5.8E-48 0.390307 24.1 TF missense won N/A N/A N/A N/A N/A N/A rs8177258 114.484 0.00054058110016 TF 0.0000 0.0000 0.0010 0.0004 blood_MEAN_CORPUSCULAR_VOL_v2 3:142232392:T:C 3 142232392 C T 0.00047816 0.886214 33.2712 8.0E-09 -0.243718 25.3 ATR missense lost rs202154338 0.0216346187286 45.4433 0.015839732736 0.0364154 24.2034802371 rs7428496 1523.18 0.00031586531076 ATR 0.0002 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:16286061:C:A 6 16286061 A C 0.00146349 0.923729 188.409 7.1E-43 0.326065 32 GMPR missense won rs778202191 0.00141499090701 512.642 0.00052004522025 0.0431982 174.501073639 6:16281187:C:T 600.774 0.00043637956609 GMPR 0.0661 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00186847 0.936787 245.037 3.1E-55 0.318128 35 GMPR frameshift won rs7765828 0.00250586400015 583.5 0.00105232116025 0.0425947 221.118608289 6:16281187:C:T 600.774 0.00056950958736 N/A N/A N/A N/A N/A blood_MEAN_CORPUSCULAR_VOL_v2 6:26157073:A:G 6 26157073 G A 0.00957035 0.979289 54.0965 1.9E-13 -0.0698785 24.7 HIST1H1E missense lost rs114374008 0.971754120347 55.1768 0.952728262084 0.0710456 0.0109450791364 6:26093141:G:A 4886.96 0.00067842537156 HIST1H1E 0.0009 0.0000 0.0001 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:26234939:C:T 6 26234939 T C 0.00057605 0.6935 39.383 3.5E-10 0.264856 25.2 HIST1H1D missense lost rs144861591 0.411125165151 4820.25 0.00335902544041 -0.248099 5.07033711549 6:26093141:G:A 4886.96 0.00330167458404 HIST1H1D 0.0043 0.0000 0.0132 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:30043301:G:C 6 30043301 C G 0.000797826 0.995511 46.0162 1.2E-11 0.199895 26.5 RNF39 missense lost rs569251450 1.00604775882 60.8197 0.761175982116 -0.312588 0.000419497524287 6:28411244:G:A 368.015 0.00120117003241 RNF39 0.0000 0.0000 0.0004 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:31129273:G:C 6 31129273 C G 0.000418493 0.873469 32.9877 9.3E-09 0.266508 24.9 TCF19 missense lost 6:28874962:A:C 0.0802716929892 40.1289 0.065986820641 0.164358 16.943356975 6:28299088:T:C 615.193 0.00034477433761 TCF19 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 6:135732649:T:C 6 135732649 C T 0.00510197 0.910051 31.4342 2.1E-08 0.0686331 21.9 AHI1 missense lost rs137966474 0.988644728627 167.038 0.186049019556 -0.0732906 0.00101909292932 6:135418635:C:T 7060.68 0.003671269281 AHI1 0.0028 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 7:50513721:A:C 7 50513721 C A 0.00517588 0.949503 30.7662 2.9E-08 0.0729145 29.9 FIGNL1 missense lost rs142756863 0.230937829541 78.1991 0.090858839184 -0.0369269 8.3012746888 rs6592965 1348.43 0.00501000658596 FIGNL1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 7:100064620:G:A 7 100064620 A G 0.00698387 0.785537 64.6177 9.1E-16 -0.0993816 24.7 TSC22D4 missense lost 7:100197866:G:A 0.216245211597 487.43 0.028667230596 -0.059277 18.493698615 7:100240296:G:A 1573.65 0.00719964129049 TSC22D4 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 7:100218512:C:T 7 100218512 T C 8.814e-05 0.888009 148.68 3.4E-34 1.25313 31 TFR2 missense won N/A N/A N/A N/A N/A N/A 7:100225803:A:C 99.5571 0.607447213321 TFR2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 7:100224387:C:T 7 100224387 T C 0.000964943 0.853484 95.2572 1.7E-22 0.284261 30 TFR2 missense won 7:99702947:G:A 0.00608944805908 113.694 0.00510197346961 0.0300052 80.9704886393 rs2406257 635.368 0.00018066854569 TFR2 0.0010 0.0000 0.0000 0.0000 blood_MEAN_CORPUSCULAR_VOL_v2 7:100225847:C:T 7 100225847 T C 0.00514751 0.994125 92.1568 8.0E-22 0.114933 21.6 NONE N/A lost 7:100239422:G:A 1.03193868333 97.3979 0.976408801956 0.116008 0.02313383514 7:100240296:G:A 1573.65 0.00312841099684 TFR2 0.0014 0.0000 0.5241 0.4540 blood_MEAN_CORPUSCULAR_VOL_v2 8:30469817:T:C 8 30469817 C T 0.00668497 0.963237 56.4707 5.7E-14 -0.0836856 24.9 GTF2E2 missense lost rs531670400 0.974048659116 58.017 0.948087795204 0.0827198 0.00963326909704 8:30279470_CAAAAAAG_C 227.224 0.00224227819729 GTF2E2 0.0000 0.0000 0.0025 0.0035 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MEAN_PLATELET_VOL_v2 10:64927837:C:T 10 64927837 T C 0.00945994 0.940726 74.0472 7.6E-18 0.0751946 26.6 JMJD1C missense lost rs185387098 0.841289464751 77.671 0.802038460356 -0.0721163 0.507431015017 10:65027610:A:T 5388.99 0.00659728944169 JMJD1C 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 11:281692:G:C 11 281692 C G 0.00526378 0.731521 43.2229 4.9E-11 -0.0932194 22.8 NLRP6 missense lost rs7926172 0.892395619333 3123.77 0.012347876641 0.115264 0.13233762802 rs11604127 3397.98 0.00183035941929 NLRP6 0.0000 0.0000 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 11:18387342:A:G 11 18387342 G A 0.00829833 0.950646 31.3286 2.2E-08 0.0577548 23.2 GTF2H1 missense lost rs144322892 0.00143138005727 38.0459 0.00117865875856 -0.0226132 29.0028967113 rs374387938 66.3996 0.00023138973225 GTF2H1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 11:64136019:G:A 11 64136019 A G 0.00241336 0.896879 32.4736 1.2E-08 0.091205 24.4 RPS6KA4 missense lost rs577299557 0.903980639921 34.9781 0.839253867664 -0.0936297 0.0786741253732 11:65394322:A:G 322.344 0.00016509166144 RPS6KA4 0.0003 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 11:65394881:G:A 11 65394881 A G 0.00742431 0.946579 106.928 4.6E-25 -0.108197 25.0 PCNXL3 missense won rs763810986 0.0285135129932 215.284 0.014162190025 0.0262071 73.8652869234 11:65394322:A:G 322.344 0.00870798783556 SIPA1 0.0039 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:6128206:G:A 12 6128206 A G 0.000145041 0.933424 68.949 1.0E-16 0.555747 25.3 VWF missense won 12:6134188_CA_C 0.000972315146175 126.032 0.00053192964496 0.0243627 64.7161090943 rs796891068 207.125 0.00021387600025 VWF 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:6128787:G:A 12 6128787 A G 0.000708744 0.741034 32.5319 1.2E-08 0.200147 22.9 VWF missense lost rs10735057 0.0312027287195 3035.74 0.000334377796 -0.0903541 22.0539230447 rs797767 3606.2 0.00022465513225 VWF 0.0020 0.0000 0.0011 0.0000 blood_MEAN_PLATELET_VOL_v2 12:49579290:A:T 12 49579290 T A 0.00781157 0.945757 72.8071 1.4E-17 0.0812716 20.9 TUBA1A missense lost rs113543437 0.985792646072 774.434 0.0926776249 -0.0879794 0.00370034141102 rs7958679 780.132 0.086350761025 TUBA1A 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:52758891:G:A 12 52758891 A G 0.00010046 0.924558 40.2142 2.3E-10 -0.487317 21.4 KRT85 missense lost rs190785963 0.46622613599 40.892 0.458498265625 0.381313 4.04599316848 rs12812148 1499.56 0.00010240630416 KRT85 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:119617383:C:G 12 119617383 G C 0.000538348 0.972493 32.5158 1.2E-08 0.196094 20.1 HSPB8 missense lost rs189088681 0.895318970431 293.612 0.099151303689 -0.389643 0.0940696856643 rs11553699 24204.0 0.00054445222225 HSPB8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:120750398:C:T 12 120750398 T C 0.0072739 0.934198 29.9087 4.5E-08 0.0549309 25.4 SIRT4 missense lost rs558961269 0.993761696245 353.112 0.084171935376 -0.297665 0.000291896166095 rs11553699 24204.0 0.00122271906276 SIRT4 0.0033 0.0000 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 12:121593936:C:T 12 121593936 T C 0.00238952 0.912288 80.829 2.5E-19 0.151543 20.2 P2RX7 missense lost rs530058315 0.569170467429 3549.93 0.0129595456 -0.372245 4.87420880975 rs11553699 24204.0 0.00169263947889 P2RX7 0.0000 0.0000 0.0000 0.0587 blood_MEAN_PLATELET_VOL_v2 12:121712218:G:A 12 121712218 A G 0.000117683 0.920807 34.9018 3.5E-09 0.443277 23.4 CAMKK2 missense lost rs35446368 0.36538139255 2711.23 0.00470357302276 -0.334618 5.46023564482 rs11553699 24204.0 0.00052272591424 CAMKK2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:121880447:CCTT:C 12 121880447 C CCTT 0.00338946 0.990644 217.65 2.9E-49 0.211126 20.8 KDM2B inframe_deletion lost rs556021468 0.991088701005 272.56 0.7914237444 -0.294192 0.00434032523528 rs11553699 24204.0 0.010539486244 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 12:122012488:G:A 12 122012488 A G 0.000128941 0.796638 32.0177 1.5E-08 0.420635 23.2 KDM2B missense lost rs35446368 0.412883923826 2711.23 0.00487586579076 -0.334618 4.09067857048 rs11553699 24204.0 0.00051966673444 KDM2B 0.0008 0.0054 0.0014 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122064778:C:CA 12 122064778 CA C 0.00282474 0.723295 30.6162 3.1E-08 -0.102564 25.3 ORAI1 frameshift lost rs375895928 0.345916763258 59.0021 0.1794962689 0.08193 5.19321122992 rs11553699 24204.0 0.00023589273744 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 12:122213001:G:A 12 122213001 A G 0.00026777 0.908299 67.5848 2.0E-16 0.415187 21.4 TMEM120B missense lost rs538114474 0.65860336322 101.753 0.437447314404 -0.259443 2.40032376357 rs11553699 24204.0 0.00142726039681 TMEM120B 0.0286 0.0125 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122217508:G:A 12 122217508 A G 0.000143764 0.842979 44.9354 2.0E-11 0.481345 25.3 RHOF missense lost 12:122199455:G:A 0.742423914477 47.1225 0.707965739649 0.434378 0.860217296823 rs11553699 24204.0 0.00081534804849 TMEM120B 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122217559:C:T 12 122217559 T C 0.00194439 0.97598 35.713 2.3E-09 0.105709 21.1 RHOF missense lost rs76153114 0.985044595791 37.0509 0.9494748481 -0.108872 0.00201200262975 12:122272892_CT_C 3392.62 0.00031383539716 TMEM120B 0.0001 0.0000 0.1525 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122231434:G:A 12 122231434 A G 0.000239315 0.942545 54.9972 1.2E-13 0.391832 29.4 RHOF missense won rs113734230 0.0181494288679 380.524 0.00262314011556 -0.0582735 41.176942422 rs12829688 3477.15 0.00019932357124 RHOF 0.0001 0.0000 0.0024 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122247609:C:T 12 122247609 T C 9.27287e-05 0.643231 34.8478 3.6E-09 0.644524 24.5 SETD1B missense lost rs556516521 1.10635746337 484.416 0.079588873225 -0.589257 0.0936324354636 rs11553699 24204.0 0.00027858280464 SETD1B 0.0021 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122292692:G:A 12 122292692 A G 0.000342293 0.944066 55.2569 1.1E-13 0.333018 24.1 HPD missense lost rs200698082 0.970709952772 442.378 0.1212502041 -0.483899 0.012028125222 rs11553699 24204.0 0.00196806689641 HPD 0.1023 0.0013 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122612511:C:T 12 122612511 T C 0.000463274 0.917463 34.1421 5.1E-09 0.226192 32 MLXIP missense lost 12:122365583:C:T 1.02714905526 14741.8 0.00237888356644 0.30792 0.00620731049633 rs11553699 24204.0 0.00184544131396 MLXIP 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122839841:G:A 12 122839841 A G 0.000175873 0.90732 42.3071 7.8E-11 0.420403 31 CLIP1 missense lost 12:121881449:C:T 0.587615882967 51.1453 0.486072501721 0.449756 2.30547174037 rs11043233 4425.45 0.00014520491001 CLIP1 0.0730 0.0026 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:122848536:C:G 12 122848536 G C 0.000207224 0.880537 41.041 1.5E-10 0.362378 27.3 CLIP1 missense lost rs34818942 0.44904392202 14310.8 0.00128778346449 -0.363417 4.46645633458 rs11553699 24204.0 0.00075121490889 CLIP1 0.0000 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 12:123036049:C:T 12 123036049 T C 0.000160759 0.839797 39.926 2.6E-10 0.424673 26.6 KNTC1 missense lost rs576151288 0.87989165487 43.5343 0.806962652721 -0.542786 0.153349808739 rs11553699 24204.0 0.00083608879104 KNTC1 0.0001 0.0000 0.0000 0.0039 blood_MEAN_PLATELET_VOL_v2 12:123061479:C:A 12 123061479 A C 0.000133004 0.808771 61.1397 5.3E-15 0.614975 24.2 KNTC1 missense lost 12:122330007_AAAGAT_A 0.787785664566 123.661 0.389492072649 -0.572911 0.77279671811 rs11553699 24204.0 0.00078199648164 KNTC1 0.0003 0.0000 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 12:123075182:A:T 12 123075182 T A 0.000350293 0.765388 34.4116 4.5E-09 0.299976 24.8 KNTC1 missense lost rs775943090 0.72013987691 112.44 0.220394569444 -0.334136 0.788671323725 rs11553699 24204.0 0.00095792726016 KNTC1 0.0000 0.0016 0.0003 0.0000 blood_MEAN_PLATELET_VOL_v2 12:123187628:T:C 12 123187628 C T 0.000359226 0.811811 46.6016 8.7E-12 0.308546 23.3 HCAR2 missense lost rs34818942 0.596908578942 14310.8 0.00194376937924 -0.363417 2.40983406935 rs11553699 24204.0 0.00101402122969 HCAR2 0.0021 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:123699339:T:C 12 123699339 C T 0.000494537 0.968762 53.882 2.1E-13 0.272831 22.1 MPHOSPH9 missense lost rs148308452 0.971392452341 2512.75 0.020829994276 -0.366532 0.011184710508 rs11553699 24204.0 0.00234145660996 MPHOSPH9 0.0000 0.0000 0.0215 0.0000 blood_MEAN_PLATELET_VOL_v2 12:123808302:C:T 12 123808302 T C 0.00107403 0.826994 83.3304 6.9E-20 0.244935 25.7 SBNO1 missense lost rs547398029 0.570756677394 125.477 0.379044623556 -0.444372 4.98214787619 rs11553699 24204.0 0.00126274333201 SBNO1 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 12:124413089:C:A 12 124413089 A C 0.00211088 0.830861 51.9979 5.6E-13 0.14315 21.3 DNAH10 missense lost rs189874078 1.00263634968 471.74 0.1105163536 -0.32294 9.02318644151e-05 rs11553699 24204.0 0.00190272184804 DNAH10 0.0002 0.0000 0.0001 0.0040 blood_MEAN_PLATELET_VOL_v2 12:124827710:C:T 12 124827710 T C 0.0005673 0.509617 57.7709 2.9E-14 0.363917 20.2 NCOR2 missense lost rs190518222 0.528829800112 166.642 0.183332974276 -0.269428 4.29908528251 rs11553699 24204.0 0.00096356230569 NCOR2 0.0001 0.0000 0.0004 0.0000 blood_MEAN_PLATELET_VOL_v2 14:65208468:A:G 14 65208468 G A 0.00115628 0.823318 60.5287 7.3E-15 0.201672 25.8 PLEKHG3 missense lost 14:65453912:C:G 0.324523079012 160.217 0.122602221316 0.122107 11.2089792121 rs11627485 271.742 0.00058478363329 PLEKHG3 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 14:69371363:G:A 14 69371363 A G 0.0011485 0.896172 34.8459 3.6E-09 -0.147901 LOW NONE N/A lost rs73275566 0.165770621036 744.222 0.00776169810025 0.0761627 12.2473530313 rs28535566 768.203 0.00716592724324 ACTN1 0.0000 0.0000 0.9545 0.0149 blood_MEAN_PLATELET_VOL_v2 14:103568634:G:T 14 103568634 T G 0.000168688 0.857774 42.487 7.1E-11 -0.467049 37 EXOC3L4 stop_gained won rs877497 0.00163495909002 267.437 0.00025974157225 0.0279748 39.1205724813 rs877497 267.437 0.00025974157225 EXOC3L4 0.0003 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 14:103570694:T:C 14 103570694 C T 0.000307239 0.901144 42.475 7.2E-11 -0.360528 23.8 EXOC3L4 missense won rs4906319 0.00106311354039 77.6205 0.00058175028025 0.0188803 39.7503251532 rs4354853 151.366 0.00011896046761 EXOC3L4 0.0000 0.0000 0.0008 0.0000 blood_MEAN_PLATELET_VOL_v2 14:103573121:G:A 14 103573121 A G 0.000260655 0.906993 66.0635 4.4E-16 -0.409483 25.3 EXOC3L4 splice_acceptor won rs4900549 0.000477122561669 82.1046 0.00038390524225 -0.0166611 63.2089524427 14:103593950:C:G 130.102 0.00012480241225 EXOC3L4 0.2175 0.9497 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 14:103573866:C:T 14 103573866 T C 0.00215663 0.954468 31.2366 2.3E-08 -0.100133 23.2 EXOC3L4 missense lost rs145260258 0.340887227644 1192.42 0.008929872004 0.0754111 5.40943747458 14:103566835:C:G 1610.71 0.00642293250624 EXOC3L4 0.0026 0.0000 0.0076 0.0013 blood_MEAN_PLATELET_VOL_v2 14:103576400:G:A 14 103576400 A G 0.000897517 0.904224 176.449 2.9E-40 -0.383302 24.7 EXOC3L4 missense won rs34976218 0.00186380860968 371.825 0.0008844676 -0.0314776 161.542607737 rs34976218 371.825 0.0008844676 EXOC3L4 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 16:24909377:T:C 16 24909377 C T 0.00128077 0.943867 41.204 1.4E-10 0.146643 31 SLC5A11 missense lost rs532700303 0.957248982459 89.0201 0.443073947044 -0.246661 0.0192401311351 rs181042823 297.016 0.086447172361 SLC5A11 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:4836485:C:T 17 4836485 T C 4.55983e-05 0.834421 131.091 2.4E-30 1.54121 35 GP1BA stop_gained won N/A N/A N/A N/A N/A N/A rs66863998 126.373 0.00034353510409 GP1BA 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:4837743:CTAATG:C 17 4837743 C CTAATG 0.000931214 0.820471 237.322 1.5E-53 0.458598 34 GP1BA frameshift won N/A N/A N/A N/A N/A N/A rs545968244 171.032 0.653352123204 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 17:4849267:T:A 17 4849267 A T 0.00156646 0.974863 78.1676 9.5E-19 -0.181457 23.3 PFN1 missense lost 17:4849268:T:C 1.00144433243 78.2805 1.0 -0.181673 4.07368694778e-05 rs66863998 126.373 0.00020546928964 PFN1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:4849268:T:C 17 4849268 C T 0.00156736 0.974249 78.2805 8.9E-19 -0.181673 22.9 PFN1 missense won rs4436834 0.00855394761991 98.428 0.00680301638416 0.0207686 64.470163376 rs66863998 126.373 0.00020546928964 PFN1 0.0004 0.0037 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:16852187:A:G 17 16852187 G A 0.00696688 0.947032 97.109 6.6E-23 -0.100058 26.1 TNFRSF13B missense won rs7225537 0.00350969738761 100.112 0.00340441908676 -0.015985 85.9438246846 rs4281782 101.447 0.00326100386704 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:26951321:C:T 17 26951321 T C 0.000956182 0.93504 29.9793 4.4E-08 0.144572 25.4 KIAA0100 missense lost rs532617884 1.04474724063 32.3477 0.968254032001 -0.160207 0.0146803492151 rs9900280 7123.95 0.00057138687369 KIAA0100 0.0001 0.0000 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 17:27306820:A:G 17 27306820 G A 0.00100825 0.833863 32.4786 1.2E-08 0.152134 22.6 SEZ6 missense lost rs11436597 0.702582152472 52.3967 0.435502325476 -0.156744 0.850246804839 rs9900280 7123.95 0.00055980506404 SEZ6 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:27896342:C:G 17 27896342 G C 0.0079459 0.92852 37.6957 8.3E-10 -0.0533831 23.8 TP53I13 missense lost rs12938068 1.00142156943 3179.09 0.011874242961 -0.103229 1.90309053363e-05 rs9900280 7123.95 0.00461239289316 TP53I13 0.0025 0.0026 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:27963753:T:C 17 27963753 C T 0.00918135 0.980764 31.0455 2.5E-08 -0.0454697 21.0 SSH2 missense lost 17:27898585:G:C 1.01052517425 36.4829 0.859916818489 -0.0533318 0.000855304412467 rs9900280 7123.95 0.00709417068361 SSH2 0.0004 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 17:42453538:G:T 17 42453538 T G 0.000844988 0.877657 163.997 1.5E-37 0.373582 27.1 ITGA2B missense won 17:42398802:G:A 0.00319054316017 173.012 0.00302429604096 0.0380598 145.993533445 rs375071427 219.569 0.00020806331536 ITGA2B 0.0916 0.0000 0.0273 0.0000 blood_MEAN_PLATELET_VOL_v2 17:42457494:C:T 17 42457494 T C 0.000205371 0.801925 34.7814 3.7E-09 0.420161 23.2 ITGA2B missense lost rs185451503 0.674970960277 35.3291 0.664507019929 -0.525059 1.10739227041 17:42530846_TGTAG_T 292.18 0.00012022464609 ITGA2B 0.0057 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 17:74383107:CG:C 17 74383107 C CG 0.00361878 0.973727 40.0283 2.5E-10 0.09101 35 SPHK1 frameshift lost 17:74445051:A:G 0.0209379419957 60.5906 0.013832347321 0.0160091 29.282261146 17:73931787:G:A 80.1335 0.00196955777209 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 18:67531573:G:A 18 67531573 A G 0.00221645 0.970617 39.5457 3.2E-10 -0.120022 26.7 CD226 missense lost rs7241191 0.177109665482 1997.75 0.00350590699449 0.0762315 13.2644852007 rs1790946 2687.64 0.002146746889 CD226 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 18:67687966:C:A 18 67687966 A C 0.0086337 0.915843 51.0717 8.9E-13 -0.0638079 23.1 RTTN missense lost rs34594414 0.371389704116 1201.03 0.015792697561 0.0654176 7.79122684109 rs1790946 2687.64 0.00562513500081 RTTN 0.0481 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 19:16280544:T:C 19 16280544 C T 0.000628026 0.831843 96.2514 1.0E-22 0.336776 25.3 CIB3 missense lost rs536829453 1.02190485169 453.093 0.217085173776 -0.337248 0.0114211470454 19:16206012:C:T 1875.88 0.025210135729 CIB3 0.1365 0.0707 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 19:41089532:G:T 19 41089532 T G 0.000266431 0.896194 33.1899 8.4E-09 -0.35021 23.3 SHKBP1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SHKBP1 0.0676 0.0011 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 19:58423509:C:A 19 58423509 A C 0.00489719 0.966885 30.7471 2.9E-08 0.0711157 35 ZNF417 stop_gained lost rs3764531 0.00134766169939 63.2249 0.00065538560025 -0.0135486 28.5310531152 rs528035312 126.504 0.00019009791376 ZNF417 0.0001 0.6034 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:43826794:G:A 1 43826794 A G 0.00666817 0.975349 33.2651 8.0E-09 -0.0534989 22.4 CDC20 missense lost rs55881586 0.015102698214 56.9156 0.008826978304 0.0402773 25.5913945252 rs785475 95.132 0.00010369756224 CDC20 0.0023 0.0007 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:115130508:A:G 1 115130508 G A 0.00564745 0.909475 154.41 1.9E-35 0.141566 29.0 DENND2C missense won N/A N/A N/A N/A N/A N/A rs192647521 81.6942 0.508463120356 DENND2C 0.0010 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:115142870:G:A 1 115142870 A G 0.00727806 0.95881 127.717 1.3E-29 0.115981 31 DENND2C missense won N/A N/A N/A N/A N/A N/A rs566716589 90.118 0.552832399729 DENND2C 0.0202 0.0000 0.0009 0.0188 blood_MEAN_PLATELET_VOL_v2 1:156875126:C:T 1 156875126 T C 0.000217742 0.950285 31.456 2.0E-08 -0.334187 24.3 PEAR1 missense lost 1:156874765:G:A 0.0597221610216 58.7847 0.031957640289 -0.0832968 17.9601115159 rs1094561 81.6973 0.00011972955241 PEAR1 0.1317 0.0037 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:156877520:A:G 1 156877520 G A 0.00115252 0.855139 147.498 6.1E-34 -0.304696 23.2 PEAR1 missense won 1:156881959:C:T 0.000397194877005 474.808 0.000123387664 0.0597226 141.677389349 1:156881959:C:T 474.808 0.000123387664 PEAR1 0.0000 0.0000 0.1181 0.5456 blood_MEAN_PLATELET_VOL_v2 1:157069134:G:A 1 157069134 A G 0.00912093 0.965247 58.2375 2.3E-14 0.0625084 25.7 ETV3L missense lost rs144508796 0.750369017873 155.499 0.281028274641 -0.0668209 1.04199452637 rs12041331 788.823 0.00064275939729 ETV3L 0.2260 0.0248 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:166829517:G:A 1 166829517 A G 0.000344926 0.826126 40.6436 1.8E-10 0.292778 40 TADA1 stop_gained lost rs540331101 0.547647144141 45.392 0.490358465536 -0.439005 2.74683418873 rs540331101 45.392 0.490358465536 TADA1 0.0198 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 1:204924020:C:T 1 204924020 T C 0.00663249 0.969839 35.8427 2.1E-09 -0.0575333 24.9 NFASC missense lost rs141008046 0.260717036576 219.261 0.042619538025 0.0478304 8.58460900571 1:205260098_AT_A 1723.89 0.00050101211889 NFASC 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:205028229:C:T 1 205028229 T C 0.00412063 0.911574 38.7551 4.8E-10 0.0866982 21.7 CNTN2 missense lost rs6703574 0.999734716207 1445.35 0.026806530529 0.0930266 6.81942751176e-07 1:205237137:T:C 4386.51 0.00231019616025 CNTN2 0.0270 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 1:205238361:C:T 1 205238361 T C 5.64156e-05 0.799425 36.4999 1.5E-09 -0.76673 27.2 TMCC2 missense lost 1:205252554_AAGAAGAAGAAAG_A 0.0101524704679 3632.41 0.00010201606009 0.110602 29.5150431171 1:205252554_AAGAAGAAGAAAG_A 3632.41 0.00010201606009 TMCC2 0.0000 0.0000 0.0006 0.0000 blood_MEAN_PLATELET_VOL_v2 1:248004375:G:C 1 248004375 C G 0.000697028 0.903321 31.0206 2.6E-08 0.192954 23.9 OR11L1 missense lost rs746585892 0.884229533475 33.8645 0.809973000225 -0.218053 0.110431358655 rs4925750 1644.19 0.00029293349409 OR11L1 0.0120 0.0000 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 1:248020849:G:T 1 248020849 T G 0.00140404 0.85441 37.8068 7.8E-10 -0.135591 35 TRIM58 stop_gained lost rs72772790 0.155655959178 1293.7 0.00454885500304 0.0696074 13.8596247872 rs4925750 1644.19 0.00293954814976 TRIM58 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:1293322:C:T 20 1293322 T C 0.00673995 0.947041 36.1452 1.8E-09 -0.0660457 25.4 SDCBP2 missense lost rs117073769 0.60286037163 85.5557 0.254693827584 0.0858936 1.80649010217 rs156355 1258.14 0.00072486946756 SDCBP2 0.0066 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:30610508:A:T 20 30610508 T A 0.00289728 0.959937 34.2514 4.8E-09 -0.0917015 26.8 CCM2L missense lost rs80236822 1.00008422949 44.0055 0.778409175625 0.0936681 6.07474976004e-08 rs143458646 74.7499 0.523818405009 CCM2L 0.0000 0.0000 0.0004 0.0000 blood_MEAN_PLATELET_VOL_v2 20:44511257:G:A 20 44511257 A G 0.00798569 0.99154 48.0522 4.2E-12 -0.0649148 27.5 ZSWIM1 stop_gained lost rs112027651 0.999382420089 53.3836 0.899574474681 0.0693182 4.58325206987e-06 rs769452263 257.055 0.0135606025 ZSWIM1 0.0028 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598607:C:T 20 57598607 T C 8.92947e-05 0.970822 52.846 3.6E-13 0.650123 36 TUBB1 stop_gained won rs151346 0.00234539634561 1071.02 0.00011572595776 -0.0548501 47.8513560612 rs151346 1071.02 0.00011572595776 TUBB1 0.0003 0.0000 0.0000 0.0068 blood_MEAN_PLATELET_VOL_v2 20:57598640:G:A 20 57598640 A G 0.000156325 0.866986 35.8327 2.2E-09 -0.445156 24.0 TUBB1 missense lost 20:57609961_AAAAC_A 0.0163543191567 372.77 0.00157206699049 0.0635542 27.2538609219 rs55905547 1187.68 0.00049050732676 TUBB1 0.0004 0.0000 0.0005 0.0010 blood_MEAN_PLATELET_VOL_v2 20:57598808:G:A 20 57598808 A G 0.00133573 0.96877 1107.02 9.8E-243 0.768135 24.8 TUBB1 missense won rs55905547 0.000319517542358 1187.68 0.00029781785476 0.0751001 1067.79762857 rs55905547 1187.68 0.00029781785476 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598882:C:T 20 57598882 T C 8.80443e-05 0.933294 120.359 5.3E-28 0.988055 41 TUBB1 stop_gained lost 20:57464139:T:G 0.943107639279 124.812 0.909459766336 0.972706 0.100265778914 rs76506142 334.865 0.021671667369 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598910:C:T 20 57598910 T C 4.22743e-05 0.761966 48.4039 3.5E-12 1.04031 26.9 TUBB1 missense won rs149214 0.000176953379766 61.8145 0.00013856350369 -0.0252887 47.1246908506 rs149214 61.8145 0.00013856350369 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598918:G:A 20 57598918 A G 5.67987e-05 0.907681 72.1419 2.0E-17 0.994535 26.5 TUBB1 missense won rs626857 0.000560869984884 368.301 0.00010986184225 -0.0328358 68.7653331729 rs626857 368.301 0.00010986184225 TUBB1 0.0004 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598966:C:T 20 57598966 T C 6.66914e-05 0.892216 45.9814 1.2E-11 0.707361 28.5 TUBB1 missense won rs6128482 0.000607189432527 71.6261 0.00038979394624 0.0217522 43.7432443758 rs6070928 83.9274 0.00027581902084 TUBB1 0.0012 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57598967:G:A 20 57598967 A G 0.000323802 0.65333 58.1762 2.4E-14 0.452332 32 TUBB1 missense won rs147263743 0.00218259103915 339.715 0.00037376875561 -0.0314731 52.8673991282 rs752444494 1171.84 0.000102232321 TUBB1 0.0006 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57599032:A:G 20 57599032 G A 2.60901e-05 0.755746 44.6196 2.4E-11 1.25421 25.6 TUBB1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TUBB1 0.0111 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57599106:T:A 20 57599106 A T 2.41926e-05 0.928852 47.7168 4.9E-12 1.21135 35 TUBB1 stop_gained won rs11570256 0.0249583416454 289.919 0.00410781010084 -0.211281 33.8309323452 rs11570256 289.919 0.00410781010084 TUBB1 0.0016 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57599203:C:T 20 57599203 T C 0.000251651 0.925563 340.814 4.2E-76 1.01005 33 TUBB1 missense won rs6026647 0.000607877104297 876.367 0.00023639985009 -0.0493423 324.215523005 rs151346 1071.02 0.00017400775744 TUBB1 0.0008 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57599557:C:T 20 57599557 T C 0.00350753 0.955208 38.0111 7.0E-10 -0.0933507 24.5 TUBB1 missense lost 20:57538516:C:A 0.093309256423 46.286 0.076627651489 -0.0332928 18.3357175989 rs151346 1071.02 0.00280001839104 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 20:57610120:G:C 20 57610120 C G 0.0037014 0.927609 35.6232 2.4E-09 -0.083634 24.0 SLMO2 missense lost rs557180907 0.60280587532 35.7165 0.601231202881 0.075167 1.78096024173 rs55905547 1187.68 0.015885577444 PRELID3B 0.0004 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 22:18609703:C:T 22 18609703 T C 0.000466536 0.671649 33.6246 6.7E-09 0.234667 30 TUBA8 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TUBA8 0.0000 0.0000 0.0016 0.0000 blood_MEAN_PLATELET_VOL_v2 22:19711776:T:C 22 19711776 C T 2.16523e-05 0.777716 48.0938 4.1E-12 1.45423 25.3 GP1BB missense won 22:19718152:C:A 0.000225330075797 55.7789 0.00019428456996 0.0260708 46.6607650608 22:19718152:C:A 55.7789 0.00019428456996 GP1BB 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 22:21235389:A:G 22 21235389 G A 0.00500353 0.993589 59.0741 1.5E-14 -0.0867587 25.3 SNAP29 missense lost rs143264657 0.99948019745 59.3352 0.995082061444 0.0866446 3.99141448698e-06 rs117003805 59.5695 0.990431001616 SNAP29 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 22:29091856:AG:A 22 29091856 A AG 0.00250711 0.876417 94.3199 2.7E-22 0.1678 35 CHEK2 frameshift won 22:29692497:T:G 0.00496129400101 270.316 0.00173111748489 0.038836 81.5007302272 rs140064 306.103 0.00112724705025 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 2:24245713:C:G 2 24245713 G C 0.00489417 0.972585 87.279 9.4E-21 -0.112325 26.0 MFSD2B missense lost rs150221884 0.897151221504 90.2548 0.867571159225 0.120366 0.24349807863 2:24030829_AAT_A 176.866 0.022071262096 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 2:68615546:A:C 2 68615546 C A 0.00871424 0.982982 144.364 3.0E-33 -0.107535 21.6 PLEK missense won 2:70057895_CT_C 0.000560697189174 163.711 0.00049443524881 -0.0249584 137.60814108 rs7349311 311.393 0.00017044346916 PLEK 0.0013 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 2:109276179:G:A 2 109276179 A G 0.000651897 0.919751 60.0523 9.2E-15 -0.264065 25.4 LIMS1 missense won rs10202224 0.00201431880097 122.662 0.00098616097024 0.0195325 54.7828303356 rs762920748 127.88 0.00093169626169 LIMS1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 2:113496453:G:A 2 113496453 A G 0.00930336 0.983872 485.826 1.2E-107 -0.186133 24.7 CKAP2L missense won N/A N/A N/A N/A N/A N/A 2:113493816:T:C 368.914 0.740983526416 NT5DC4 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 2:113496572:C:T 2 113496572 T C 0.000140731 0.910584 32.0029 1.5E-08 -0.399784 23.6 CKAP2L missense won rs369170347 0.00050405405259 33.3656 0.00048346774641 0.016899 30.5820274941 rs369170347 33.3656 0.00048346774641 NT5DC4 0.0000 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 2:192701067:CT:C 2 192701067 C CT 6.01447e-05 0.615567 33.1673 8.5E-09 -0.833134 32 SDPR frameshift won N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 2:192701265:T:C 2 192701265 C T 0.00692203 0.911042 152.369 5.3E-35 0.127247 22.4 SDPR missense lost rs149408739 0.890390078877 163.525 0.829645900801 -0.136778 0.484596650012 2:192696255:A:G 544.252 0.00084823067536 SDPR 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 3:50368871:C:T 3 50368871 T C 0.00235839 0.887247 49.0552 2.5E-12 -0.120328 25.4 RASSF1 missense lost rs533923471 0.116529025216 51.9288 0.110080622656 0.33377 21.2802471072 rs12631365 82.8559 0.00055759265956 RASSF1 0.3754 0.0000 0.0001 0.0000 blood_MEAN_PLATELET_VOL_v2 3:56702553:C:T 3 56702553 T C 0.0095833 0.984847 43.0448 5.4E-11 0.0546834 20.4 FAM208A missense lost rs149518529 0.979946135619 67.3721 0.626098717696 -0.0761344 0.00437164219352 3:56849749:C:T 17719.3 0.00159740105625 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 3:57493410:T:A 3 57493410 A T 0.00186751 0.947917 41.6579 1.1E-10 0.137518 26.4 DNAH12 missense lost rs374959214 1.10325608135 52.2036 0.880386247521 -0.150722 0.105649736885 3:56849749:C:T 17719.3 0.00178961149444 DNAH12 0.0015 0.0000 0.0022 0.1174 blood_MEAN_PLATELET_VOL_v2 3:57898399:A:G 3 57898399 G A 0.00202859 0.738337 30.9567 2.6E-08 -0.117467 25.9 SLMAP missense lost rs113580223 0.450809206243 878.366 0.015888098304 0.113721 3.34216792793 3:56849749:C:T 17719.3 0.00053740976041 SLMAP 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 3:58110119:G:C 3 58110119 C G 0.00574956 0.943845 32.8419 1.0E-08 0.0614273 27.7 FLNB missense lost rs141387583 1.04658704665 37.4107 0.918772092676 -0.0678791 0.0174162514816 3:56849749:C:T 17719.3 0.00127117919296 FLNB 0.0861 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 3:124303696:C:T 3 124303696 T C 0.00207025 0.874463 624.128 9.5E-138 -0.479188 40 KALRN stop_gained won rs11720789 0.0137874049466 794.719 0.010827859249 0.0675636 486.163159447 rs650571 1170.27 0.00074672667169 N/A N/A N/A N/A N/A blood_MEAN_PLATELET_VOL_v2 3:128780764:A:G 3 128780764 G A 0.000826255 0.9345 544.759 1.7E-120 0.684904 23.2 GP9 missense won N/A N/A N/A N/A N/A N/A rs556451147 323.85 0.482320527049 GP9 0.2665 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 4:2941317:G:A 4 2941317 A G 0.00429934 0.954914 75.836 3.1E-18 0.110081 21.6 NOP14 missense lost rs13139439 0.987992625305 84.7017 0.884579751441 -0.120196 0.00274998763149 4:3255258:A:G 159.263 0.00089470979689 NOP14 0.0001 0.0000 0.0252 0.0000 blood_MEAN_PLATELET_VOL_v2 5:60063694:G:A 5 60063694 A G 0.000484891 0.951023 42.9592 5.6E-11 0.238702 38 ELOVL7 stop_gained won rs2409837 0.00979116476454 322.811 0.001302993409 -0.040087 34.8781678932 rs2409837 322.811 0.001302993409 ELOVL7 0.0010 0.2568 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:74892232:C:T 5 74892232 T C 0.000609988 0.823717 31.4033 2.1E-08 0.202511 36 POLK stop_gained lost rs550183103 1.27675985965 188.73 0.212443559056 -0.445614 0.530209582158 5:75996909:G:A 4796.12 0.00427627060624 POLK 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75858226:T:C 5 75858226 C T 6.18001e-05 0.871882 38.9925 4.3E-10 0.687961 25.0 IQGAP2 start_lost lost rs114685606 0.105064286512 3419.58 0.00119801823376 -0.232607 17.8114563884 5:75953299:G:A 3569.57 0.00113216771529 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75866423:C:T 5 75866423 T C 0.000665276 0.910187 573.23 1.1E-126 0.776813 41 IQGAP2 stop_gained won rs10647961 0.00872682157276 2058.81 0.00242978999041 0.0959631 471.133096335 rs10647961 2058.81 0.00242978999041 IQGAP2 0.0904 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75896742:C:T 5 75896742 T C 5.46502e-05 0.750511 53.2448 2.9E-13 0.939287 38 IQGAP2 stop_gained won rs34727413 0.00112550347843 454.249 0.00013192589881 -0.0414362 49.7321582811 rs7729082 470.496 0.000118635664 IQGAP2 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75902053:C:T 5 75902053 T C 6.60883e-05 0.857218 31.9078 1.6E-08 0.646463 39 IQGAP2 stop_gained lost rs34469953 0.015649744182 1235.33 0.00040422308809 -0.0840635 24.4238851468 rs10647961 2058.81 0.00022518303721 IQGAP2 0.0000 0.5946 0.0744 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75927675:A:G 5 75927675 G A 9.09941e-05 0.843249 33.4173 7.4E-09 0.536519 LOW NONE N/A lost 5:76406470:C:T 0.0313264170259 961.173 0.001089132004 0.157417 22.6349077469 5:76406470:C:T 961.173 0.001089132004 IQGAP2 0.9967 0.9339 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75932944:G:A 5 75932944 A G 0.000120637 0.864993 93.2556 4.6E-22 0.745734 40 IQGAP2 stop_gained won rs10078999 0.00124297155296 625.024 0.00018545537124 0.041583 86.7959121774 rs10078999 625.024 0.00018545537124 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75954282:A:G 5 75954282 G A 8.39807e-05 0.819502 40.6051 1.9E-10 0.636623 34 IQGAP2 splice_acceptor won rs75813045 0.0101288420559 559.089 0.00073563000625 -0.0696673 32.843213636 rs250743 969.44 0.000106977649 IQGAP2 0.5489 0.9937 0.0002 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75960968:G:C 5 75960968 C G 0.00590259 0.930086 879.532 2.8E-193 0.33657 27.7 IQGAP2 missense won rs250721 0.047148389862 2050.81 0.020220555601 0.0953249 539.042989889 rs10647961 2058.81 0.019465272324 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75960989:T:C 5 75960989 C T 0.000227666 0.67766 109.423 1.3E-25 0.685571 26.8 IQGAP2 missense lost rs548496802 0.539277887999 1161.67 0.050797045924 -0.443931 7.72165733093 5:75996909:G:A 4796.12 0.00321629631376 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75973081:A:C 5 75973081 C A 0.000433908 0.900287 45.2453 1.7E-11 0.27102 24.7 IQGAP2 missense won rs10078999 0.00724400955459 625.024 0.00052439168016 0.041583 37.8712442914 rs10078999 625.024 0.00052439168016 IQGAP2 0.0001 0.0425 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:75979027:G:A 5 75979027 A G 0.000335799 0.796565 47.259 6.2E-12 0.37246 24.2 IQGAP2 missense won 5:75996909:G:A 0.0219563425882 4796.12 0.00021634879744 0.273798 34.2912668595 5:75996909:G:A 4796.12 0.00021634879744 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:76003044:A:G 5 76003044 G A 7.89528e-05 0.987626 40.4504 2.0E-10 0.663135 32 IQGAP2 missense won rs72775791 0.0073307599978 460.906 0.00064336800609 -0.0571082 33.8202172068 rs72775791 460.906 0.00064336800609 IQGAP2 0.0019 0.0012 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:140773719:G:A 5 140773719 A G 0.00615633 0.978822 77.5579 1.3E-18 0.0873512 25.5 PCDHGA8 missense lost 5:140762406:T:C 1.0 77.5579 1.0 0.0873512 0.0 rs72792333 228.868 0.168699954361 PCDHGB4 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:140789415:G:A 5 140789415 A G 0.00618004 0.978169 76.3631 2.4E-18 0.0868518 23.3 PCDHGB6 missense lost 5:140755573:C:T 1.00731350983 77.1793 0.996660792241 0.0870401 0.00101739942453 rs72792333 228.868 0.168111480196 PCDHGB6 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 5:140864784:C:T 5 140864784 T C 0.00615401 0.993138 81.609 1.7E-19 0.087835 21.9 PCDHGC4 missense lost rs146358809 0.999503345083 82.617 0.987308525956 -0.0880552 5.03379367276e-06 rs72792333 228.868 0.174286210576 PCDHGC4 0.0029 0.0000 0.0390 0.0000 blood_MEAN_PLATELET_VOL_v2 6:31595795:C:T 6 31595795 T C 0.00388054 0.993255 32.3554 1.3E-08 -0.0724842 22.5 PRRC2A missense lost rs146761687 0.988472552972 34.2213 0.934576560225 0.0791725 0.00108110305863 rs3819288 595.174 0.0121528576 PRRC2A 0.0278 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:31779728:C:G 6 31779728 G C 0.00390819 0.997931 30.9892 2.6E-08 -0.071952 22.9 HSPA1L missense lost 6:31831721:G:T 0.997879276146 31.349 0.9864263761 -0.0728046 3.48802422147e-05 rs3819288 595.174 0.012720005089 HSPA1L 0.0005 0.0006 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:32008500:G:A 6 32008500 A G 0.00572604 0.823815 33.3603 7.7E-09 0.0794106 24.7 CYP21A2 missense lost 6:31843523:G:T 0.898970916986 46.2668 0.648195671236 0.0697628 0.0897185198307 rs3819288 595.174 0.00038039431369 CYP21A2 0.0006 0.0000 0.0042 0.0000 blood_MEAN_PLATELET_VOL_v2 6:32168996:C:G 6 32168996 G C 0.0089672 0.99637 30.4823 3.4E-08 0.0515482 24.2 NOTCH4 missense lost rs11967437 0.993660380841 43.2494 0.7003346596 -0.0606876 0.000307251488308 rs3819288 595.174 0.00069947025625 NOTCH4 0.0037 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:32802938:C:T 6 32802938 T C 0.00565004 0.989658 36.4889 1.5E-09 0.0648087 23.5 TAP2 missense lost rs138148759 1.0826528325 49.6764 0.795243031696 -0.0691414 0.0598687901668 rs3819288 595.174 0.00034759127844 XXbac-BPG246D15.9 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:36507854:T:A 6 36507854 A T 0.0003819 0.975544 117.075 2.8E-27 -0.476645 22.2 STK38 missense won rs7747978 0.103751562886 456.487 0.026609113129 0.152804 53.8008532412 rs7747978 456.487 0.026609113129 STK38 0.0000 0.0000 0.0001 0.0001 blood_MEAN_PLATELET_VOL_v2 6:36698471:G:A 6 36698471 A G 0.0050722 0.976836 150.267 1.5E-34 -0.143524 32 RAB44 missense lost rs4711455 0.987335446256 235.339 0.630426472036 0.179547 0.00606382464294 rs116957783 689.989 0.204726386089 RAB44 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:36926952:A:G 6 36926952 G A 0.00632477 0.980602 60.1199 8.9E-15 -0.0785985 24.9 PI16 missense lost rs111718632 0.914543847424 80.0036 0.687247632016 0.11058 0.114716551311 rs116957783 689.989 0.070011043216 PI16 0.0003 0.0035 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 6:109774960:C:T 6 109774960 T C 0.00429681 0.944229 61.1455 5.3E-15 0.0967069 32 MICAL1 missense won rs7773815 0.00512342625856 69.738 0.00449216295696 0.0133506 52.7054154452 rs2057149 346.882 0.000742889536 MICAL1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 7:2296552:A:G 7 2296552 G A 0.00375068 0.988495 65.9042 4.7E-16 0.112563 24.4 SNX8 missense won N/A N/A N/A N/A N/A N/A rs559517076 59.5723 0.755449535556 SNX8 0.0000 0.0000 0.0000 0.0001 blood_MEAN_PLATELET_VOL_v2 7:98991711:T:G 7 98991711 G T 0.00208535 0.89628 32.4859 1.2E-08 0.109587 25.5 ARPC1B missense lost rs112138417 0.0153693048413 34.279 0.014565351969 -0.0198416 24.9304367093 rs112108851 144.995 0.00259599421081 ARPC1B 0.0001 0.0000 0.0000 0.0069 blood_MEAN_PLATELET_VOL_v2 9:215228:C:G 9 215228 G C 0.00440449 0.962838 89.6638 2.8E-21 -0.117617 21.2 C9orf66 missense lost rs62533403 0.337148586351 287.146 0.105277536225 0.0814207 15.7681536971 9:331490:G:T 1091.59 0.00168702418756 DOCK8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:271626:G:T 9 271626 T G 0.000904297 0.92625 137.212 1.1E-31 0.343446 34 DOCK8 splice_acceptor won rs752379926 0.0142140816567 935.199 0.00208548402241 -0.063631 106.444738441 9:331490:G:T 1091.59 0.00110257866601 DOCK8 0.0755 0.9539 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:304670:C:T 9 304670 T C 0.000794728 0.81183 46.3756 9.8E-12 -0.228351 23.3 DOCK8 missense lost rs117869333 0.142684696134 62.086 0.106579396225 0.0891325 17.9571952748 9:331490:G:T 1091.59 0.00034266082321 DOCK8 0.0000 0.0000 0.0000 0.1109 blood_MEAN_PLATELET_VOL_v2 9:420579:A:G 9 420579 G A 0.00460366 0.949284 163.255 2.2E-37 -0.16849 32 DOCK8 missense won 9:241322:G:A 0.0573919800543 303.497 0.030871895616 -0.0496811 94.4037569257 9:331490:G:T 1091.59 0.00219178467225 DOCK8 0.0000 0.0000 0.0018 0.0069 blood_MEAN_PLATELET_VOL_v2 9:5081828:G:C 9 5081828 C G 0.00104669 0.937121 66.5705 3.4E-16 -0.216608 21.9 JAK2 missense won rs7875870 0.000265646605347 102.396 0.00017270427889 0.0158549 64.4181631618 rs7875870 102.396 0.00017270427889 JAK2 0.0001 0.0000 0.0000 0.0001 blood_MEAN_PLATELET_VOL_v2 9:113148268:T:C 9 113148268 C T 0.00484822 0.939119 34.7949 3.7E-09 0.0689648 22.8 SVEP1 missense lost 9:113312231:G:C 0.220980166269 130.777 0.058794610576 0.0577302 9.77074248034 9:113312231:G:C 130.777 0.058794610576 SVEP1 0.0021 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135210058:C:G 9 135210058 G C 0.000185748 0.590946 31.794 1.7E-08 0.44374 25.7 SETX missense lost 9:135781401:C:G 0.597195375746 47.4299 0.4003219441 0.826267 1.6414298781 9:135864513:C:T 2713.79 0.00265736126016 SETX 0.0002 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135781401:C:G 9 135781401 G C 7.53691e-05 0.595221 47.4299 5.7E-12 0.826267 22.8 TSC1 missense lost 9:135864513:C:T 0.301910412351 2713.79 0.00527659865604 0.495812 9.6274592529 9:135864513:C:T 2713.79 0.00527659865604 TSC1 0.0007 0.0000 0.0019 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135863638:C:T 9 135863638 T C 0.00280871 0.901684 35.8021 2.2E-09 0.0894334 22.5 GFI1B missense lost rs114968084 0.265032839769 363.139 0.026129752609 -0.098373 8.42803037131 rs114968084 363.139 0.026129752609 GFI1B 0.0039 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135863854:A:T 9 135863854 T A 3.50055e-05 0.895301 31.8673 1.7E-08 0.808016 34 GFI1B missense lost 9:135844886:G:A 0.0031063305596 293.371 0.00033742383481 0.0562431 28.4140765516 9:135844886:G:A 293.371 0.00033742383481 GFI1B 0.0000 0.0000 0.5149 0.0351 blood_MEAN_PLATELET_VOL_v2 9:135864458:C:A 9 135864458 A C 0.000161172 0.916116 138.41 5.9E-32 0.806521 24.6 GFI1B missense won N/A N/A N/A N/A N/A N/A rs10119210 118.842 0.0001092025 GFI1B 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135864485:G:A 9 135864485 A G 6.39706e-05 0.781542 189.122 4.9E-43 1.61495 27.1 GFI1B missense won N/A N/A N/A N/A N/A N/A rs554422821 62.7688 0.00286933778244 GFI1B 0.0383 0.0005 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135864488:G:A 9 135864488 A G 7.3335e-05 0.837678 201.502 9.8E-46 1.43327 26.7 GFI1B missense won N/A N/A N/A N/A N/A N/A 9:136325370:T:C 151.37 0.785937213961 GFI1B 0.0262 0.0006 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135864494:A:G 9 135864494 G A 2.82959e-05 0.854152 72.9493 1.3E-17 1.36948 23.7 GFI1B missense won 9:135616378:G:A 0.000777429488218 151.021 0.00037553013796 0.0480628 68.9380065198 9:135616378:G:A 151.021 0.00037553013796 GFI1B 0.0000 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:135864506:G:A 9 135864506 A G 9.58238e-05 0.688071 51.6204 6.7E-13 0.656698 23.2 GFI1B missense won N/A N/A N/A N/A N/A N/A rs504557 34.1096 0.00013085758449 GFI1B 0.0013 0.0000 0.0000 0.0000 blood_MEAN_PLATELET_VOL_v2 9:136220682:G:A 9 136220682 A G 0.000101411 0.762356 34.1361 5.1E-09 0.51938 21.0 SURF1 missense lost 9:135864513:C:T 0.646122692849 2713.79 0.00812741916484 0.495812 1.31381465519 9:135864513:C:T 2713.79 0.00812741916484 SURF1 0.0015 0.0000 0.0016 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MEAN_RETICULOCYTE_VOL_v2 10:103766311:G:A 10 103766311 A G 0.00665714 0.97401 33.1875 8.4E-09 -0.0649361 23.1 C10orf76 missense lost rs74930510 0.963539655234 34.1346 0.936805244769 0.0640588 0.0112352786689 rs144452309 133.869 0.000578691136 C10orf76 0.0000 0.0000 0.0000 0.0011 blood_MEAN_RETICULOCYTE_VOL_v2 11:4132858:A:T 11 4132858 T A 0.00113312 0.968239 41.6744 1.1E-10 -0.190649 25.0 RRM1 missense lost rs761910563 1.01133209435 46.4005 0.9083233636 0.199843 0.0013303912705 rs725518 157.732 0.00149919968025 RRM1 0.0008 0.0000 0.0000 0.0003 blood_MEAN_RETICULOCYTE_VOL_v2 11:19246240:G:A 11 19246240 A G 0.000193676 0.737794 85.8715 1.9E-20 0.773085 39 E2F8 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A E2F8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 11:67198887:C:T 11 67198887 T C 0.00405431 0.653001 59.5672 1.2E-14 -0.144751 25.7 RPS6KB2 missense lost rs553917782 0.122084926506 188.569 0.038565497161 0.056925 25.2131193641 rs10274 295.167 0.00323933999104 RPS6KB2 0.0001 0.0015 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 11:116701354:G:A 11 116701354 A G 0.00224711 0.92045 39.5928 3.1E-10 0.132338 31 APOC3 splice_donor won rs180327 0.0022190184521 91.5159 0.00096002064964 -0.0193365 35.950503957 11:116648917:C:G 271.391 0.00023193462436 APOC3 0.0001 0.0000 0.1104 0.8914 blood_MEAN_RETICULOCYTE_VOL_v2 11:119044535:C:G 11 119044535 G C 0.00938238 0.914248 60.0689 9.2E-15 -0.0784482 24.2 NLRX1 missense lost rs546110583 0.79329539447 61.4269 0.775757554441 0.0820014 0.717989204183 rs8551 414.451 0.011384676601 NLRX1 0.0000 0.0000 0.0038 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 12:12022496:T:C 12 12022496 C T 0.00924387 0.96914 31.7822 1.7E-08 0.0589611 22.3 ETV6 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ETV6 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 12:112673047:T:A 12 112673047 A T 0.00691302 0.996032 42.6159 6.7E-11 0.079752 20.7 HECTD4 missense lost rs112439578 0.985148657733 45.2993 0.92679129 -0.0861445 0.002367478946 12:112979034_AAT_A 286.143 0.071683101169 HECTD4 0.0173 0.0039 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 13:73319139:G:A 13 73319139 A G 0.00403982 0.9402 95.5992 1.4E-22 -0.148814 28.6 BORA missense won N/A N/A N/A N/A N/A N/A rs184739375 84.8636 0.932875881025 BORA 0.0472 0.1196 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 16:765861:G:A 16 765861 A G 0.00260336 0.945039 86.5988 1.3E-20 -0.172713 23.7 METRN missense lost rs117498884 0.982500215028 107.766 0.789519325401 0.179433 0.00668871236042 rs4580163 423.104 0.00301298894649 METRN 0.1253 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 16:4310464:G:A 16 4310464 A G 0.00021824 0.819794 30.8973 2.7E-08 0.410593 26.0 TFAP4 missense won rs7200658 0.00018058806672 37.7032 0.00014798965801 0.0125447 30.072464943 rs4786466 38.6997 0.00011481551104 TFAP4 0.0000 0.0000 0.0265 0.0001 blood_MEAN_RETICULOCYTE_VOL_v2 16:67231976:G:A 16 67231976 A G 0.0001584 0.867439 37.5359 9.0E-10 0.490601 24.6 E2F4 missense won rs9926387 0.000239781616176 58.977 0.00015260896225 0.0133457 36.3824223436 rs35258664 71.4129 0.00011587876609 E2F4 0.0118 0.0000 0.0001 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 17:42331919:C:T 17 42331919 T C 5.10498e-05 0.704317 30.2861 3.7E-08 -0.772307 22.6 SLC4A1 missense lost rs9747308 0.00151668444504 150.208 0.00030580566129 0.0386168 27.9730723535 rs9747308 150.208 0.00030580566129 SLC4A1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 17:46894356:G:A 17 46894356 A G 0.00248307 0.969958 34.7953 3.7E-09 0.11161 35 TTLL6 stop_gained lost rs771735575 1.00747642285 86.8854 0.403467606481 -0.268737 0.000484428131114 rs575705078 431.041 0.088019615761 TTLL6 0.0006 0.0000 0.4033 0.1612 blood_MEAN_RETICULOCYTE_VOL_v2 17:47788784:G:A 17 47788784 A G 0.000372879 0.915052 36.1939 1.8E-09 0.330293 28.3 FAM117A missense lost rs532346435 0.724375067674 41.3833 0.633539586304 -0.382901 0.802438130561 rs12449950 62.4403 0.000294431281 FAM117A 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 17:74383107:CG:C 17 74383107 C CG 0.00361224 0.973727 48.3917 3.5E-12 -0.106576 35 SPHK1 frameshift won N/A N/A N/A N/A N/A N/A 17:74383109:T:C 48.3917 1.0 N/A N/A N/A N/A N/A blood_MEAN_RETICULOCYTE_VOL_v2 19:40964064:G:A 19 40964064 A G 0.00676469 0.872551 51.8484 6.0E-13 -0.0895458 32 BLVRB missense won 19:40843264:G:A 0.00223918634305 54.9576 0.002112505444 0.0148983 47.0575613328 rs5828065 56.5158 0.00201166602256 BLVRB 0.0000 0.0000 0.0546 0.0985 blood_MEAN_RETICULOCYTE_VOL_v2 1:158450142:C:T 1 158450142 T C 0.00329147 0.952435 63.58 1.5E-15 0.136812 35 OR10R2 stop_gained lost 1:158665692_TG_T 0.959621954072 65.1684 0.936232343281 -0.132971 0.0264517817708 rs2482963 3993.01 0.00881306010841 OR10R2 0.0009 0.0000 0.2879 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:158450451:G:A 1 158450451 A G 0.00841049 0.967157 119.677 7.4E-28 0.108694 23.2 OR10R2 missense lost rs141522869 1.0195053903 241.228 0.505792638481 -0.114479 0.0112734047676 rs2482963 3993.01 0.022853275929 OR10R2 0.0018 0.0000 0.0015 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:158583604:C:A 1 158583604 A C 0.00080061 0.972715 114.092 1.2E-26 -0.360139 27.8 SPTA1 missense won rs2022003 0.00988594905527 3980.76 0.00028333978929 -0.13036 92.5320038507 rs2482963 3993.01 0.00025661797249 SPTA1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:158605757:C:T 1 158605757 T C 0.00194865 0.94596 60.246 8.4E-15 0.178064 27.8 SPTA1 missense lost rs555568708 0.710293773457 74.8676 0.571573800625 -0.205741 1.48899253733 rs2482963 3993.01 0.00406838589921 SPTA1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:158613207:C:A 1 158613207 A C 0.000409753 0.860242 60.4068 7.7E-15 -0.372887 25.2 SPTA1 missense lost rs186270716 0.23406395985 263.708 0.053616328704 0.212712 16.0960453632 rs2482963 3993.01 0.00018011518849 SPTA1 0.0017 0.0320 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:158669770:CAG:C 1 158669770 C CAG 0.00496834 0.922999 44.6863 2.3E-11 0.0934415 24.8 OR6K2 frameshift lost rs12405509 0.998789296287 3156.17 0.014141252889 -0.122971 1.63852538622e-05 rs2482963 3993.01 0.012552065296 N/A N/A N/A N/A N/A blood_MEAN_RETICULOCYTE_VOL_v2 1:158669774:C:CT 1 158669774 CT C 0.00496834 0.922999 44.6863 2.3E-11 0.0934415 24.6 OR6K2 frameshift lost 1:158669770:CAG:C 1.0 44.6863 1.0 0.0934415 0.0 rs2482963 3993.01 0.012552065296 N/A N/A N/A N/A N/A blood_MEAN_RETICULOCYTE_VOL_v2 1:158747043:C:G 1 158747043 G C 0.00591502 0.980491 38.0363 6.9E-10 0.0721309 22.1 OR6N2 missense lost rs34802073 0.930258561513 3630.24 0.00974690205696 -0.130026 0.0479376109678 rs2482963 3993.01 0.00797588314084 OR6N2 0.0001 0.0000 0.0002 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 1:203276246:C:G 1 203276246 G C 0.000195291 0.923343 37.8563 7.6E-10 0.413593 28.5 BTG2 missense won rs10920607 0.00505196105144 300.995 0.00063538780761 -0.0414545 32.6661128329 rs17534202 785.835 0.00020341605376 BTG2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 20:3785297:C:T 20 3785297 T C 0.000824317 0.919314 33.0153 9.1E-09 0.206894 LOW NONE N/A lost 20:3739895:G:C 0.00480632025169 60.307 0.00263123857936 0.0172733 28.5962371137 rs6084653 105.961 0.00059246967649 CDC25B 0.0003 0.0000 0.8150 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 20:35675512:G:A 20 35675512 A G 0.00137147 0.909193 93.7778 3.5E-22 0.253896 29.3 RBL1 missense won N/A N/A N/A N/A N/A N/A rs182322127 78.2136 0.794875667364 RBL1 0.0006 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 20:35696466:T:A 20 35696466 A T 0.000167307 0.736956 50.7418 1.1E-12 0.59097 23.4 RBL1 missense won rs56371715 0.000227564726004 55.7758 0.00020702605456 -0.0154118 49.2224417067 rs2145943 84.7224 0.00010193527369 RBL1 0.0714 0.0000 0.0004 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 22:50966041:C:T 22 50966041 T C 0.000565967 0.795133 30.7191 3.0E-08 -0.232316 25.4 TYMP missense lost rs2269379 0.0194152022324 224.833 0.00265271352025 0.0447842 22.7548142923 rs749768657 1079.66 0.00039294339984 TYMP 0.0005 0.0000 0.0000 0.0264 blood_MEAN_RETICULOCYTE_VOL_v2 22:50989742:C:T 22 50989742 T C 0.00694406 0.946317 32.241 1.4E-08 -0.0650865 20.5 SYCE3 missense lost 22:50971266:C:T 0.976968965402 2392.0 0.013168251009 -0.0977196 0.00432534035749 22:50971266:C:T 2392.0 0.013168251009 SYCE3 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 2:27455332:C:T 2 27455332 T C 5.62463e-05 0.952651 39.2169 3.8E-10 0.849206 33 CAD missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CAD 0.0004 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 2:47238530:G:A 2 47238530 A G 0.00217688 0.90437 31.6799 1.8E-08 0.110814 23.7 TTC7A missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TTC7A 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 3:50326254:G:A 3 50326254 A G 0.000650597 0.636099 30.0937 4.1E-08 -0.26805 31 IFRD2 missense lost rs41311615 0.810583404852 36.6096 0.6663130384 0.242429 0.298989754597 3:50359246_AGGG_A 156.761 0.000113188321 IFRD2 0.0000 0.0000 0.0032 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 3:50326729:C:T 3 50326729 T C 0.000535583 0.750212 35.1032 3.1E-09 -0.253022 26.5 IFRD2 missense lost rs9877046 0.00794805561158 292.19 0.00095486562081 -0.0349579 29.123170463 3:50329826:A:G 309.723 0.00086627794276 IFRD2 0.0045 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 3:142232392:T:C 3 142232392 C T 0.000478134 0.886214 30.3484 3.6E-08 -0.250664 25.3 ATR missense lost rs138793897 0.015699322586 319.247 0.00149241597124 0.0432454 23.219726156 rs71153975 1119.8 0.00031875460369 ATR 0.0002 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 4:145035851:C:T 4 145035851 T C 0.00445659 0.924095 98.5803 3.1E-23 -0.152532 23.5 GYPA missense won N/A N/A N/A N/A N/A N/A rs190334693 97.5719 0.887541104836 GYPA 0.0001 0.0000 0.0000 0.1250 blood_MEAN_RETICULOCYTE_VOL_v2 4:154544148:C:T 4 154544148 T C 0.000443086 0.915907 53.9821 2.0E-13 -0.327938 31 KIAA0922 missense won N/A N/A N/A N/A N/A N/A rs745985207 46.756 0.555765777009 KIAA0922 0.0015 0.0000 0.0015 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 6:28227993:G:A 6 28227993 A G 0.0070482 0.976277 36.507 1.5E-09 0.069605 23.2 NKAPL missense lost 6:30124811:C:T 1.07768118059 187.261 0.210096639769 0.142474 0.0530335540826 6:30124811:C:T 187.261 0.210096639769 NKAPL 0.0007 0.0000 0.0004 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 6:30124811:C:T 6 30124811 T C 0.00867419 0.934131 187.261 1.3E-42 0.142474 22.4 TRIM10 missense won N/A N/A N/A N/A N/A N/A rs139079590 125.754 0.699235457209 TRIM10 0.0001 0.0266 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 6:49604368:C:T 6 49604368 T C 0.00022875 0.858624 99.1274 2.4E-23 -0.670627 34 RHAG splice_donor won N/A N/A N/A N/A N/A N/A N/A N/A N/A RHAG 0.0004 0.0000 0.3148 0.9729 blood_MEAN_RETICULOCYTE_VOL_v2 7:50513721:A:C 7 50513721 C A 0.00516994 0.949503 49.5882 1.9E-12 0.0959776 29.9 FIGNL1 missense lost rs6592965 0.306273601191 3007.89 0.005049239364 -0.104226 9.88956183361 rs6592965 3007.89 0.005049239364 FIGNL1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:41542151:A:C 8 41542151 C A 0.000464658 0.888053 33.2876 7.9E-09 -0.285167 27.4 ANK1 missense lost 8:41571692:G:T 0.0217128311866 196.03 0.00368702769681 -0.067539 24.200329632 rs4737010 2797.8 0.00015655765129 ANK1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:41547827:G:A 8 41547827 A G 0.0006796 0.967838 65.1314 7.0E-16 -0.294541 22.4 ANK1 missense lost rs72638986 0.458210728695 1680.24 0.017761692529 0.21238 6.7987697874 rs4737010 2797.8 0.00010994151609 ANK1 0.0253 0.0074 0.0007 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:41550195:C:T 8 41550195 T C 0.00246677 0.936583 29.8679 4.6E-08 -0.102215 22.6 ANK1 missense lost 8:41457110_CTCT_C 0.128775617283 43.8928 0.087628432441 0.0410136 12.2777744303 rs4737010 2797.8 0.00073353763921 ANK1 0.0000 0.0000 0.0024 0.0004 blood_MEAN_RETICULOCYTE_VOL_v2 8:41552791:C:T 8 41552791 T C 0.000289138 0.937657 37.5969 8.7E-10 -0.380101 26.6 ANK1 missense lost rs185199017 0.0338090663365 47.6793 0.026659705284 0.119245 25.0419502134 rs113630867 1156.71 0.00051820424881 ANK1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:41575677:G:A 8 41575677 A G 0.00135209 0.91167 30.7514 2.9E-08 -0.13962 29.2 ANK1 missense lost rs569451 0.0184615424632 1633.17 0.00034761738025 -0.0842198 22.9625324142 rs4737010 2797.8 0.00018053684496 ANK1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:42256264:C:G 8 42256264 G C 0.00230415 0.971133 45.897 1.2E-11 -0.126855 25.6 VDAC3 missense lost rs192226598 0.63416229051 50.5569 0.575710667536 0.176386 1.90363057028 rs4737010 2797.8 0.000244891201 VDAC3 0.0117 0.0000 0.0138 0.0000 blood_MEAN_RETICULOCYTE_VOL_v2 8:86242013:A:G 8 86242013 G A 0.000439721 0.810343 46.9743 7.2E-12 -0.345195 23.9 CA1 missense won N/A N/A N/A N/A N/A N/A rs35718625 40.2209 0.00090064811664 CA1 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MEAN_SPHERED_CELL_VOL_v2 10:101295456:T:G 10 101295456 G T 0.00837965 0.978121 75.4661 3.7E-18 -0.0898549 33 NKX2-3 missense won rs7901824 0.00479128550746 111.913 0.003230899281 -0.0213738 65.3802867299 rs4590800 115.047 0.00279294281289 NKX2-3 0.0000 0.0000 0.0021 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 11:4132858:A:T 11 4132858 T A 0.00113266 0.968239 44.0393 3.2E-11 -0.195479 25.0 RRM1 missense lost rs185864381 0.962984396526 44.4977 0.9530640625 0.208255 0.0153709901465 rs11030976 119.92 0.00148287376561 RRM1 0.0008 0.0000 0.0000 0.0003 blood_MEAN_SPHERED_CELL_VOL_v2 11:5248004:G:A 11 5248004 A G 1.69813e-05 0.609495 75.7369 3.2E-18 -2.56325 42 HBB stop_gained won N/A N/A N/A N/A N/A N/A rs185233978 63.3706 0.00286941277561 HBB 0.0001 0.0033 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 11:14865399:C:T 11 14865399 T C 0.00106851 0.906863 58.2734 2.3E-14 0.224961 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs558528882 34.8079 0.443926373284 PDE3B 0.1111 0.0139 0.0003 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 11:19246240:G:A 11 19246240 A G 0.000192403 0.737794 70.0515 5.8E-17 0.65835 39 E2F8 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A E2F8 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 11:67198887:C:T 11 67198887 T C 0.00406022 0.653001 53.2841 2.9E-13 -0.129693 25.7 RPS6KB2 missense lost rs71457764 0.138425543832 170.919 0.043154245696 0.0547109 21.0106599599 rs12799746 197.284 0.00379064325124 RPS6KB2 0.0001 0.0015 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 11:116701354:G:A 11 116701354 A G 0.0022496 0.92045 65.0102 7.5E-16 0.154326 31 APOC3 splice_donor won rs180327 0.00146491145866 99.3046 0.00095901083041 -0.0192629 60.1290123648 11:116648917:C:G 304.567 0.00023426445249 APOC3 0.0001 0.0000 0.1104 0.8914 blood_MEAN_SPHERED_CELL_VOL_v2 12:111885310:G:A 12 111885310 A G 0.00201571 0.885884 40.8144 1.7E-10 -0.130802 32 SH2B3 missense lost rs551014092 1.05027413667 45.1752 0.9488902921 0.13449 0.0251608915901 12:112979034_AAT_A 418.57 0.00010484531236 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 12:112673047:T:A 12 112673047 A T 0.00690627 0.996032 55.5824 9.0E-14 0.087931 20.7 HECTD4 missense lost rs541436680 0.896816741956 68.191 0.730994220324 -0.0786474 0.156106879397 12:112979034_AAT_A 418.57 0.071603337744 HECTD4 0.0173 0.0039 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 13:73319139:G:A 13 73319139 A G 0.00404065 0.9402 89.2815 3.4E-21 -0.143039 28.6 BORA missense won N/A N/A N/A N/A N/A N/A rs191078878 77.4067 0.918666657841 BORA 0.0472 0.1196 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 15:43499436:G:A 15 43499436 A G 0.00628562 0.975953 44.3104 2.8E-11 -0.0782872 24.1 EPB42 missense won N/A N/A N/A N/A N/A N/A rs144065237 39.8179 0.9716439184 EPB42 0.0001 0.0000 0.0075 0.0002 blood_MEAN_SPHERED_CELL_VOL_v2 15:78786319:C:T 15 78786319 T C 0.000736521 0.917141 32.5436 1.2E-08 0.196426 28.9 IREB2 missense lost 15:78556895:G:A 0.00438681906839 50.1828 0.00284485690384 0.0199894 28.3754380537 rs4886565 106.025 0.00069207929476 IREB2 0.0000 0.0000 0.0478 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 16:169168:C:T 16 169168 T C 0.00022473 0.697212 32.3391 1.3E-08 -0.405528 27.1 NPRL3 missense won rs3760045 0.00132247360489 36.4781 0.00117241868836 0.0254394 30.0297911684 16:282573_GC_G 104.946 0.000149670756 NPRL3 0.0000 0.0000 0.0000 0.0163 blood_MEAN_SPHERED_CELL_VOL_v2 16:765861:G:A 16 765861 A G 0.00260209 0.945039 41.4252 1.2E-10 -0.11723 23.7 METRN missense lost rs146317318 1.16126488286 63.728 0.754858618276 0.138511 0.249581267827 rs4262946 319.132 0.00305135816881 METRN 0.1253 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 16:841311:C:T 16 841311 T C 0.00021832 0.872002 31.8237 1.7E-08 0.386463 46 CHTF18 stop_gained won 16:308154_AT_A 0.000550131082002 54.9207 0.00031877245764 -0.0152117 30.348365503 rs56308933 137.502 0.00010082368921 CHTF18 0.0001 0.0000 0.0203 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 16:67166731:G:A 16 67166731 A G 0.00679962 0.967352 51.5806 6.9E-13 -0.076936 22.8 C16orf70 missense lost 16:67006541:C:T 1.01533507393 55.5093 0.943474198276 -0.0766033 0.00300945023015 16:67242169:C:T 116.557 0.00010102461121 C16orf70 0.0001 0.0480 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 16:67231976:G:A 16 67231976 A G 0.000158243 0.867439 40.1348 2.4E-10 0.495389 24.6 E2F4 missense won rs9926387 0.000178568933979 47.0435 0.00015234471184 0.0119125 39.0693266716 rs35258664 54.3917 0.000115670025 E2F4 0.0118 0.0000 0.0001 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 17:4908241:G:A 17 4908241 A G 0.00477389 0.938712 35.4201 2.7E-09 -0.0848886 22.5 KIF1C missense lost rs117100864 0.3931105542 118.415 0.117586582281 0.0529365 4.92835178189 17:4901982:C:T 122.936 0.104603083776 KIF1C 0.0000 0.0000 0.1794 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 17:16852187:A:G 17 16852187 G A 0.00697893 0.947032 87.3929 8.9E-21 -0.109921 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs572423904 71.6245 0.473791305625 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 17:42331919:C:T 17 42331919 T C 5.09574e-05 0.704317 34.3651 4.6E-09 -0.775991 22.6 SLC4A1 missense won rs9747308 0.00088941800773 100.116 0.00030529524529 0.0306159 32.3459164883 rs9747308 100.116 0.00030529524529 SLC4A1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 17:47788784:G:A 17 47788784 A G 0.00037341 0.915052 33.8687 5.9E-09 0.308376 28.3 FAM117A missense lost rs532346435 0.703604061131 37.7428 0.631382803216 -0.348665 0.87997187431 rs35014661 48.1595 0.00014459581504 FAM117A 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 18:21116700:A:G 18 21116700 G A 0.000823314 0.880176 42.7221 6.3E-11 -0.224097 24.1 NPC1 missense won rs148477096 0.000214202050626 44.4826 0.00020572451761 0.0491876 41.4807203404 18:18533532:T:A 46.8676 0.00018744621921 NPC1 0.0020 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 18:67687966:C:A 18 67687966 A C 0.0086407 0.915843 33.5122 7.1E-09 -0.0572723 23.1 RTTN missense lost rs187927307 0.943312472237 34.4239 0.918329307025 0.0610885 0.0277139071073 rs187927307 34.4239 0.918329307025 RTTN 0.0481 0.0000 0.0001 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 19:12995833:T:TC 19 12995833 TC T 0.00020942 0.842305 113.244 1.9E-26 -0.730264 35 KLF1 frameshift lost 19:12995834:C:CC 0.886361119768 115.016 0.872705350969 -0.7259 0.387979542754 rs2974753 125.824 0.00017969134401 N/A N/A N/A N/A N/A blood_MEAN_SPHERED_CELL_VOL_v2 1:158450142:C:T 1 158450142 T C 0.00329132 0.952435 60.8305 6.2E-15 0.129797 35 OR10R2 stop_gained lost rs149223700 0.956790330326 68.2632 0.8526121569 -0.134444 0.0290243124619 rs2022003 4951.82 0.00825888358656 OR10R2 0.0009 0.0000 0.2879 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158450451:G:A 1 158450451 A G 0.00840685 0.967157 123.549 1.1E-28 0.105487 23.2 OR10R2 missense lost rs141522869 1.04072410804 254.245 0.5057343225 -0.113529 0.0502078182217 rs2022003 4951.82 0.0207676921 OR10R2 0.0018 0.0000 0.0015 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158517543:A:T 1 158517543 T A 0.00351518 0.951114 40.8773 1.6E-10 0.103858 23.7 OR6Y1 missense lost rs857693 1.00411376743 4780.6 0.00858583853604 -0.139961 0.000172587669202 rs2022003 4951.82 0.00807738980049 OR6Y1 0.0004 0.0000 0.0006 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158583604:C:A 1 158583604 A C 0.000802659 0.972715 247.231 1.0E-55 -0.514401 27.8 SPTA1 missense won 1:158577167:A:T 0.00774413279275 351.44 0.00544784229025 -0.0498211 205.632560622 rs2022003 4951.82 0.00028660119849 SPTA1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158605757:C:T 1 158605757 T C 0.00194558 0.94596 47.5745 5.3E-12 0.14905 27.8 SPTA1 missense lost rs555568708 0.7491739642 62.1954 0.573058084036 -0.176293 0.860015815643 rs2022003 4951.82 0.00378269281296 SPTA1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158613207:C:A 1 158613207 A C 0.000410168 0.860242 73.874 8.3E-18 -0.407098 25.2 SPTA1 missense lost rs186270716 0.186063117598 255.66 0.0537636969 0.201301 23.8880764103 rs2022003 4951.82 0.00019109191696 SPTA1 0.0017 0.0320 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 1:158669770:CAG:C 1 158669770 C CAG 0.00496441 0.922999 51.0993 8.8E-13 0.0982816 24.8 OR6K2 frameshift lost rs11265005 0.995320280529 3768.62 0.013495701241 -0.128047 0.000280422318135 rs2022003 4951.82 0.011898664561 N/A N/A N/A N/A N/A blood_MEAN_SPHERED_CELL_VOL_v2 1:158669774:C:CT 1 158669774 CT C 0.00496441 0.922999 51.0993 8.8E-13 0.0982816 24.6 OR6K2 frameshift lost 1:158669770:CAG:C 1.0 51.0993 1.0 0.0982816 0.0 rs2022003 4951.82 0.011898664561 N/A N/A N/A N/A N/A blood_MEAN_SPHERED_CELL_VOL_v2 1:158747043:C:G 1 158747043 G C 0.00591275 0.980491 40.2917 2.2E-10 0.0741139 22.1 OR6N2 missense lost rs857689 1.0029126713 4534.69 0.00891109568196 -0.139851 8.53309858382e-05 rs2022003 4951.82 0.00746067517504 OR6N2 0.0001 0.0000 0.0002 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 20:35675512:G:A 20 35675512 A G 0.00136947 0.909193 84.2957 4.3E-20 0.238689 29.3 RBL1 missense won N/A N/A N/A N/A N/A N/A rs182322127 78.4016 0.794875667364 RBL1 0.0006 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 20:35696466:T:A 20 35696466 A T 0.000167242 0.736956 35.6091 2.4E-09 0.46342 23.4 RBL1 missense won rs56371715 0.000399813953303 68.8668 0.00020673263524 -0.0170083 34.1993043013 rs2145943 98.2926 0.00010181819025 RBL1 0.0714 0.0000 0.0004 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 22:50966041:C:T 22 50966041 T C 0.000566305 0.795133 35.9124 2.1E-09 -0.244291 25.4 TYMP missense lost rs3213442 0.0138065683111 229.679 0.00215878249129 0.0403545 27.9687157166 rs131789 1011.95 0.00020808639504 TYMP 0.0005 0.0000 0.0000 0.0264 blood_MEAN_SPHERED_CELL_VOL_v2 22:50989742:C:T 22 50989742 T C 0.0069438 0.946317 37.9389 7.3E-10 -0.0689152 20.5 SYCE3 missense lost rs131793 0.952681416416 1471.41 0.024563979441 -0.0859413 0.0217545742814 22:50971266:C:T 2136.98 0.013171005225 SYCE3 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 2:24245713:C:G 2 24245713 G C 0.00488986 0.972585 72.5018 1.7E-17 -0.115177 26.0 MFSD2B missense lost rs150221884 0.890866032216 74.4319 0.867764908521 0.122187 0.228528334472 2:24030829_AAT_A 417.253 0.0220463104 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 2:27454345:T:C 2 27454345 C T 9.48418e-05 0.848204 39.4075 3.4E-10 0.573166 27.3 CAD missense won rs146270437 0.00101298762714 96.3883 0.00041415099049 -0.0226919 36.9389375336 2:27519153:G:T 112.03 0.000267224409 CAD 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 3:124303696:C:T 3 124303696 T C 0.00206817 0.874463 31.0107 2.6E-08 -0.1172 40 KALRN stop_gained lost 3:124483089:C:G 0.00594531882944 39.3805 0.00468172061361 -0.0132995 26.4128530287 rs55968914 71.0971 0.000419881081 N/A N/A N/A N/A N/A blood_MEAN_SPHERED_CELL_VOL_v2 3:133476769:C:T 3 133476769 T C 0.00119223 0.942472 50.6325 1.1E-12 0.191644 24.1 TF missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TF 0.0000 0.0000 0.0010 0.0004 blood_MEAN_SPHERED_CELL_VOL_v2 4:110638824:C:T 4 110638824 T C 0.0077043 0.943901 40.9808 1.5E-10 0.0698094 26.2 PLA2G12A missense lost rs187325356 0.982641323975 50.2388 0.801560299401 -0.0760156 0.00311420932745 rs11568904 166.324 0.00432454857769 PLA2G12A 0.2418 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 4:145035851:C:T 4 145035851 T C 0.00445573 0.924095 88.088 6.3E-21 -0.138372 23.5 GYPA missense lost rs190334693 0.909938140413 90.3247 0.887405448484 0.138828 0.187150456538 rs190334693 90.3247 0.887405448484 GYPA 0.0001 0.0000 0.0000 0.1250 blood_MEAN_SPHERED_CELL_VOL_v2 6:49604368:C:T 6 49604368 T C 0.000229519 0.858624 198.683 4.0E-45 -0.924391 34 RHAG splice_donor won N/A N/A N/A N/A N/A N/A rs35365087 55.9726 0.00010410324961 RHAG 0.0004 0.0000 0.3148 0.9729 blood_MEAN_SPHERED_CELL_VOL_v2 7:50513721:A:C 7 50513721 C A 0.00517086 0.949503 39.4402 3.4E-10 0.0844506 29.9 FIGNL1 missense lost rs6592965 0.305864550212 2387.43 0.00505286397225 -0.0901066 7.87873614795 rs6592965 2387.43 0.00505286397225 FIGNL1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 7:100218512:C:T 7 100218512 T C 8.81855e-05 0.888009 37.1406 1.1E-09 0.676998 31 TFR2 missense won rs11429233 0.000116557338528 39.6762 0.00010910847025 -0.0129499 36.3429763681 rs11429233 39.6762 0.00010910847025 TFR2 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:41542151:A:C 8 41542151 C A 0.000463848 0.888053 41.062 1.5E-10 -0.285222 27.4 ANK1 missense lost rs536993453 0.837111701576 42.63 0.806321386116 0.325553 0.297105299173 rs4737010 4089.58 0.00015626500036 ANK1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:41547827:G:A 8 41547827 A G 0.000679548 0.967838 71.6289 2.6E-17 -0.297396 22.4 ANK1 missense lost rs139851312 0.966468697249 73.456 0.942429340944 0.319068 0.0204787608333 rs4737010 4089.58 0.00011054840164 ANK1 0.0253 0.0074 0.0007 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:41550195:C:T 8 41550195 T C 0.00246677 0.936583 43.6773 3.9E-11 -0.125677 22.6 ANK1 missense lost 8:41457110_CTCT_C 0.107402370442 53.4965 0.087688831129 0.0448857 19.7402332173 rs4737010 4089.58 0.00073323974656 ANK1 0.0000 0.0000 0.0024 0.0004 blood_MEAN_SPHERED_CELL_VOL_v2 8:41575677:G:A 8 41575677 A G 0.00134858 0.91167 102.615 4.1E-24 -0.258513 29.2 ANK1 missense won rs569451 0.00802022401868 2380.0 0.00034579633936 -0.0988766 85.0584782706 rs4737010 4089.58 0.00017937780624 ANK1 0.0001 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:42256264:C:G 8 42256264 G C 0.00230227 0.971133 39.1644 3.9E-10 -0.1103 25.6 VDAC3 missense lost rs186914641 0.660475346899 43.2962 0.597445518916 0.138163 1.3739913176 rs4737010 4089.58 0.00024396565636 VDAC3 0.0117 0.0000 0.0138 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:42287696:G:A 8 42287696 A G 0.00079267 0.797642 30.513 3.3E-08 0.212587 23.2 SLC20A2 missense lost rs4737010 0.238115077784 4089.58 0.00177661407001 -0.138512 7.99972583229 rs4737010 4089.58 0.00177661407001 SLC20A2 0.0001 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:48882589:G:C 8 48882589 C G 0.00276606 0.954529 35.0729 3.2E-09 -0.104936 27.4 MCM4 missense lost rs117180919 0.884166869146 38.7615 0.800028280249 0.103719 0.124996783663 rs72638668 102.02 0.021316292001 MCM4 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 8:86242013:A:G 8 86242013 G A 0.000440471 0.810343 30.6203 3.1E-08 -0.253589 23.9 CA1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CA1 0.0000 0.0000 0.0000 0.0000 blood_MEAN_SPHERED_CELL_VOL_v2 9:5081828:G:C 9 5081828 C G 0.00104907 0.937121 33.5189 7.1E-09 -0.154344 21.9 JAK2 missense lost rs12005199 0.0134546678617 398.76 0.00113097017401 0.0405542 26.1938858055 rs35797651 608.33 0.00011643920649 JAK2 0.0001 0.0000 0.0000 0.0001 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_MONOCYTE_COUNT_v2 10:73515155:G:A 10 73515155 A G 0.000161203 0.762422 74.6382 5.7E-18 0.734338 22.3 C10orf54 missense won rs9415040 0.000163332133519 93.4761 0.0001304164 -0.0180548 72.7426166199 rs7919533 95.851 0.00011838745636 CDH23 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 11:63974995:C:G 11 63974995 G C 0.00416644 0.958009 29.8008 4.8E-08 0.0817415 21.5 FERMT3 missense lost 11:64026144:G:A 0.0101362497991 35.671 0.00846817731529 -0.0113105 24.1022421942 rs2325787 54.6424 0.00354702433761 FERMT3 0.0000 0.0000 0.0024 0.0016 blood_MONOCYTE_COUNT_v2 12:57867885:G:A 12 57867885 A G 0.00470987 0.915322 62.2109 3.1E-15 -0.111874 27.5 ARHGAP9 missense won rs10649122 0.0194791147345 63.1527 0.019188621529 0.0195089 46.05746135 rs61352607 70.1013 0.013118266225 ARHGAP9 0.0008 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 13:29286824:C:T 13 29286824 T C 8.93281e-05 0.940291 31.865 1.7E-08 0.591301 26.5 SLC46A3 missense lost rs531655558 0.885527587177 1847.56 0.015272757889 -0.819052 0.110829008679 rs76428106 3636.21 0.00259163464561 SLC46A3 0.0000 0.0000 0.0000 0.0199 blood_MONOCYTE_COUNT_v2 14:23587838:G:T 14 23587838 T G 0.00816307 0.900526 53.918 2.1E-13 0.0838623 24.5 CEBPE missense won rs12434881 0.0598119715483 365.192 0.00883081196176 -0.0363604 30.7700454623 rs2239630 516.706 0.00621733827001 CEBPE 0.0002 0.0000 0.0000 0.0005 blood_MONOCYTE_COUNT_v2 14:93142861:T:C 14 93142861 C T 0.00569431 0.929367 33.6629 6.6E-09 -0.0764047 27.5 RIN3 missense won rs57281976 0.000830056280066 50.9888 0.00054800469025 -0.0160029 31.7511388559 rs61975764 80.6546 0.00018255792996 RIN3 0.0000 0.0000 0.0001 0.0000 blood_MONOCYTE_COUNT_v2 15:80191338:A:G 15 80191338 G A 0.00210944 0.971396 64.4411 9.9E-16 -0.174073 22.6 ST20 missense won 15:80252408_TA_T 0.0497085612313 827.776 0.00386973573184 -0.0670417 38.9095506356 rs2562750 830.982 0.00364299159184 ST20 0.0001 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 16:2158419:G:A 16 2158419 A G 0.00399532 0.835764 30.5954 3.2E-08 -0.0889893 23.8 PKD1 missense lost rs9926191 0.0425919109238 37.021 0.035199388225 0.0237652 19.2700768792 rs9926191 37.021 0.035199388225 PKD1 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 16:85952145:T:C 16 85952145 C T 0.00424931 0.870221 282.48 2.2E-63 0.264068 23.9 IRF8 missense won rs56177354 0.245107639891 1329.32 0.052085281284 -0.149001 72.015650261 rs144009594 2506.03 0.00228502164361 IRF8 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 16:85952280:G:A 16 85952280 A G 0.00176882 0.977227 83.7681 5.6E-20 0.210101 21.5 IRF8 missense won rs144009594 0.0307548208596 2506.03 0.00102802955641 0.0982145 56.9634616443 rs144009594 2506.03 0.00102802955641 IRF8 0.0000 0.0000 0.0009 0.0000 blood_MONOCYTE_COUNT_v2 17:16852187:A:G 17 16852187 G A 0.00697064 0.947032 335.531 6.0E-75 -0.210419 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs568982652 227.949 0.646187684164 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 17:56348226:T:G 17 56348226 G T 0.00645166 0.884416 121.341 3.2E-28 -0.141225 32 MPO splice_acceptor won 17:56436109:C:T 0.0666366588387 271.604 0.029770396681 -0.0442507 66.7806396747 rs2632516 410.358 0.00434642207076 MPO 0.1133 0.9751 0.0006 0.0000 blood_MONOCYTE_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00977768 0.967311 77.0613 1.7E-18 -0.0888359 26.0 S1PR2 missense won N/A N/A N/A N/A N/A N/A rs141801008 68.7771 0.878866875441 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 19:17476153:T:G 19 17476153 G T 0.00371707 0.914963 33.7167 6.4E-09 0.100138 21.9 PLVAP missense won rs4808728 0.000370682758857 72.3324 0.00017278839601 0.0175678 32.430894631 19:18109314:A:G 75.4594 0.00012953171344 PLVAP 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 1:36932047:C:T 1 36932047 T C 0.00826829 0.978817 33.0622 8.9E-09 -0.0629232 24.9 CSF3R missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CSF3R 0.0002 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 1:150789884:C:T 1 150789884 T C 0.00838155 0.766246 46.1089 1.1E-11 -0.0791807 23.1 ARNT missense lost rs201944701 0.622516615683 68.6665 0.4180139716 0.0670919 2.05286839936 rs4970966 933.202 0.018725732964 ARNT 0.0019 0.0033 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 1:150960593:G:A 1 150960593 A G 0.00786425 0.741733 42.2434 8.1E-11 -0.0791959 23.3 ANXA9 missense lost 1:150789884:C:T 0.909402668334 46.1089 0.833163677284 -0.0791807 0.0908462066922 rs4970966 933.202 0.015614751681 ANXA9 0.0201 0.0000 0.0001 0.0000 blood_MONOCYTE_COUNT_v2 22:17586757:T:C 22 17586757 C T 0.00583897 0.901863 2130.92 3.3E-465 -0.599145 25.2 IL17RA missense won N/A N/A N/A N/A N/A N/A rs9606618 1942.97 0.747157970689 IL17RA 0.0000 0.0000 0.0003 0.0000 blood_MONOCYTE_COUNT_v2 22:17588658:G:A 22 17588658 A G 0.00104011 0.87878 842.249 3.5E-185 0.903487 22.4 IL17RA missense won N/A N/A N/A N/A N/A N/A rs531425523 280.695 0.232628723856 IL17RA 0.0053 0.0000 0.0579 0.2601 blood_MONOCYTE_COUNT_v2 22:24574054:G:A 22 24574054 A G 0.00468551 0.898898 34.786 3.7E-09 0.0918107 26.1 CABIN1 missense lost rs55870750 0.0791237135686 35.5192 0.077490413641 -0.0276232 17.968532969 rs7288670 185.601 0.00179557282564 CABIN1 0.0381 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 2:68615546:A:C 2 68615546 C A 0.00871881 0.982982 74.1584 7.2E-18 -0.0892568 21.6 PLEK missense won N/A N/A N/A N/A N/A N/A rs190855339 69.3927 0.667492268004 PLEK 0.0013 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 2:69040504:G:A 2 69040504 A G 0.00736358 0.983755 86.4176 1.5E-20 0.105578 24.3 ARHGAP25 missense won N/A N/A N/A N/A N/A N/A rs77712266 58.249 0.573498746209 ARHGAP25 0.0000 0.0000 0.0000 0.2078 blood_MONOCYTE_COUNT_v2 3:42727348:G:C 3 42727348 C G 0.00117112 0.902336 32.129 1.4E-08 0.165382 25.3 KLHL40 missense lost 3:42906116:T:C 0.732976758356 1484.49 0.015863906304 0.152981 0.664926416513 3:42906116:T:C 1484.49 0.015863906304 KLHL40 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 3:46399764:T:A 3 46399764 A T 0.000656031 0.957483 42.4191 7.4E-11 -0.241697 24.6 CCR2 missense won rs796891867 0.00352375022505 124.043 0.00120502013956 -0.022358 37.5324782705 rs2213290 293.485 0.000429691441 CCR2 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 3:128344820:C:T 3 128344820 T C 0.00304942 0.973547 36.2068 1.8E-09 0.105723 33 RPN1 missense lost rs76871974 0.870843453219 38.1198 0.827141137729 -0.127614 0.161612125665 rs4045811 1425.88 0.00536084623684 RPN1 0.0087 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 5:82789493:G:A 5 82789493 A G 0.00306915 0.942045 44.3833 2.7E-11 0.113717 32 VCAN missense won N/A N/A N/A N/A N/A N/A rs142071354 36.1962 0.631950272209 VCAN 0.0000 0.0000 0.0000 0.0020 blood_MONOCYTE_COUNT_v2 6:31605016:T:C 6 31605016 C T 0.00829426 0.99288 74.3143 6.7E-18 0.0972455 29.9 PRRC2A missense lost 6:31599556:A:C 1.00039031207 74.8642 0.993042145225 0.0971764 2.82977319941e-06 6:33074389:G:C 222.095 0.00098900815225 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_MONOCYTE_COUNT_v2 6:32063460:G:A 6 32063460 A G 0.00341331 0.818934 38.4914 5.5E-10 0.114781 24.0 TNXB missense lost 6:32006792:G:A 0.772615069433 73.5152 0.404529072676 0.0987828 0.563689992332 6:33074389:G:C 222.095 0.00200637701476 TNXB 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 6:32151458:G:A 6 32151458 A G 0.00535735 0.979931 42.6966 6.4E-11 0.0929875 26.1 AGER missense lost rs55932544 1.00070823024 76.4606 0.558808576225 -0.0979331 5.35215258128e-06 6:33074389:G:C 222.095 0.00146839940809 AGER 0.0865 0.0000 0.0047 0.0000 blood_MONOCYTE_COUNT_v2 6:35086272:C:T 6 35086272 T C 0.00451724 0.986063 40.8005 1.7E-10 0.0974699 24.4 TCP11 missense lost rs112687196 0.9993500021 40.8357 0.998488571536 -0.097261 4.31092612928e-06 6:33048606:G:C 174.252 0.00017892807696 TCP11 0.0776 0.0000 0.0001 0.0000 blood_MONOCYTE_COUNT_v2 6:35086275:T:C 6 35086275 C T 0.00450341 0.987776 40.911 1.6E-10 0.0973805 23.9 TCP11 missense lost 6:35086073:T:G 1.0 40.911 1.0 0.0973805 0.0 6:33048606:G:C 174.252 0.00017937780624 TCP11 0.0000 0.0000 0.0001 0.0000 blood_MONOCYTE_COUNT_v2 7:27204653:C:T 7 27204653 T C 0.000941893 0.932692 34.8062 3.6E-09 0.187312 23.9 HOXA9 missense won rs71539503 0.00263710848103 36.2211 0.00253409546404 -0.0134603 31.323197146 rs875896 62.8244 0.00027796558729 HOXA9 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 9:79118400:C:T 9 79118400 T C 0.00778619 0.950605 43.7037 3.8E-11 -0.073494 23.3 GCNT1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A GCNT1 0.0000 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 9:114886569:C:T 9 114886569 T C 0.00318918 0.888348 34.4026 4.5E-09 -0.102595 25.3 SUSD1 missense lost 9:113981679_CAT_C 0.0102416364215 1749.46 0.00020139867225 0.0827048 27.7917859086 rs824017 2669.45 0.00012198981601 SUSD1 0.0001 0.0000 0.0000 0.0000 blood_MONOCYTE_COUNT_v2 9:117354865:A:C 9 117354865 C A 0.00516746 0.933193 41.1517 1.4E-10 0.0912757 22.7 ATP6V1G1 missense won N/A N/A N/A N/A N/A N/A rs77637251 31.6879 0.00011045379409 ATP6V1G1 0.0000 0.1039 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_NEUTROPHIL_COUNT_v2 10:73515155:G:A 10 73515155 A G 0.000161853 0.762422 35.5147 2.5E-09 0.537618 22.3 C10orf54 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CDH23 0.0000 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 11:118067537:C:G 11 118067537 G C 0.0017216 0.841659 30.2207 3.9E-08 -0.132186 25.6 AMICA1 splice_acceptor lost rs541897906 0.914780203048 35.7123 0.774111386896 0.140304 0.0573392237625 rs11216919 48.3502 0.00057054577321 AMICA1 0.0868 0.9576 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 12:111856181:G:A 12 111856181 A G 0.00106116 0.940356 40.0745 2.4E-10 0.193515 22.1 SH2B3 missense lost rs530203431 0.985845988795 45.1973 0.874107193969 -0.212415 0.0020214227012 rs565349424 199.455 0.000631617424 SH2B3 0.0012 0.0000 0.0181 0.0000 blood_NEUTROPHIL_COUNT_v2 12:111885295:G:A 12 111885295 A G 0.000492169 0.861631 30.286 3.7E-08 0.276582 32 SH2B3 missense lost 12:112850727_CAAAT_C 0.000975125671432 146.766 0.00020122273609 0.0259728 28.4240506739 12:112850727_CAAAT_C 146.766 0.00020122273609 SH2B3 0.0001 0.0000 0.0001 0.0000 blood_NEUTROPHIL_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00200424 0.885884 166.374 4.6E-38 0.299969 32 SH2B3 missense lost rs570074821 0.989477375371 173.438 0.949176702049 -0.295124 0.004629857791 rs565349424 199.455 0.001018375744 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_NEUTROPHIL_COUNT_v2 14:23587838:G:T 14 23587838 T G 0.00816981 0.900526 30.7705 2.9E-08 -0.0606836 24.5 CEBPE missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A CEBPE 0.0002 0.0000 0.0000 0.0005 blood_NEUTROPHIL_COUNT_v2 17:4863328:G:A 17 4863328 A G 0.00288681 0.91862 31.3377 2.2E-08 -0.102488 26.0 SPAG7 missense lost 17:4805494:G:A 0.969655802288 32.6462 0.930790800625 -0.102781 0.00732527398688 17:5326162:G:A 59.287 0.00168195953689 SPAG7 0.0000 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 17:37370522:T:C 17 37370522 C T 0.00690194 0.895857 34.7871 3.7E-09 0.073403 24.4 STAC2 missense lost rs77849840 1.02125328902 43.565 0.8154812416 -0.0846758 0.00388715439856 17:38171668:C:G 3176.05 0.00654680029129 STAC2 0.4401 0.0000 0.0138 0.0158 blood_NEUTROPHIL_COUNT_v2 17:37427083:T:G 17 37427083 G T 0.00348223 0.982507 31.7136 1.8E-08 -0.0907745 22.9 FBXL20 missense lost rs550198618 0.97897251212 34.1683 0.908641713529 0.094697 0.00354293208841 rs140683487 1377.5 0.00347965492996 FBXL20 0.0000 0.0000 0.0007 0.0000 blood_NEUTROPHIL_COUNT_v2 17:37822174:C:T 17 37822174 T C 0.0052446 0.969355 32.2426 1.4E-08 -0.0787164 29.6 TCAP missense lost rs141153199 1.0015298915 33.8698 0.953413592041 0.079556 1.88520814243e-05 17:38171668:C:G 3176.05 0.00266386047876 TCAP 0.0001 0.0000 0.0001 0.0000 blood_NEUTROPHIL_COUNT_v2 17:38324554:C:T 17 38324554 T C 0.0058477 0.938853 33.6844 6.5E-09 0.0779072 29.4 CASC3 missense lost rs180735555 1.05208093816 107.992 0.328160559609 -0.0850176 0.0222654708302 17:38171668:C:G 3176.05 0.00565649897409 CASC3 0.0417 0.0000 0.0001 0.0000 blood_NEUTROPHIL_COUNT_v2 17:56277684:C:T 17 56277684 T C 0.00335501 0.956261 45.0435 1.9E-11 0.118416 21.9 EPX missense lost 17:56350196:G:A 1.11787513697 55.7326 0.903474963169 0.127637 0.147870971263 rs1295926 244.736 0.00103921772161 EPX 0.0001 0.0000 0.0011 0.0000 blood_NEUTROPHIL_COUNT_v2 17:56350196:G:A 17 56350196 A G 0.0035574 0.944163 55.7326 8.3E-14 0.127637 32 MPO missense won rs1292041 0.00542376735606 191.582 0.00157781345089 0.0268114 47.8258887771 rs1295926 244.736 0.00102717045025 MPO 0.0077 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 17:56351017:C:T 17 56351017 T C 0.00128879 0.898067 38.8406 4.6E-10 0.184354 24.2 MPO missense won rs7217118 0.00146962504592 74.498 0.00076621008025 0.017807 35.9197187995 rs1295926 244.736 0.00019234361344 MPO 0.5760 0.0208 0.0001 0.0000 blood_NEUTROPHIL_COUNT_v2 17:72758167:G:A 17 72758167 A G 0.00448661 0.935543 39.3173 3.6E-10 0.0938065 32 SLC9A3R1 missense won rs4789094 0.00679770062427 56.0203 0.00477089974089 0.0145765 33.1012884195 rs777785838 68.6701 0.00052941868281 SLC9A3R1 0.0006 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 17:72759559:C:G 17 72759559 G C 0.00132844 0.923027 67.9622 1.7E-16 0.236629 24.1 SLC9A3R1 missense won rs777785838 0.000321068951667 68.6701 0.00031775914564 -0.0186989 65.5484731888 rs777785838 68.6701 0.00031775914564 SLC9A3R1 0.0002 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00978314 0.967311 34.4772 4.3E-09 -0.0628937 26.0 S1PR2 missense lost rs10409243 0.0225136552114 119.166 0.00651366827329 0.022966 24.9071096465 rs10409243 119.166 0.00651366827329 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 1:36940984:C:T 1 36940984 T C 0.00120981 0.921203 30.6704 3.1E-08 0.168518 27.1 CSF3R missense lost rs566921175 1.04243261156 42.3594 0.754775213284 -0.198956 0.0135203552192 rs3917933 339.293 0.00065023470009 CSF3R 0.0001 0.0001 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 1:173930928:G:C 1 173930928 C G 0.00667695 0.97342 40.5888 1.9E-10 -0.0763737 20.0 RC3H1 missense won N/A N/A N/A N/A N/A N/A rs114017545 40.385 0.943149803281 RC3H1 0.0007 0.0000 0.0006 0.0000 blood_NEUTROPHIL_COUNT_v2 22:17586757:T:C 22 17586757 C T 0.0058362 0.901863 51.8818 5.9E-13 -0.0944587 25.2 IL17RA missense won rs181407 0.000172054658165 53.576 0.00016661388241 -0.0144699 50.5296634414 rs9605364 64.2606 0.000117418896 IL17RA 0.0000 0.0000 0.0003 0.0000 blood_NEUTROPHIL_COUNT_v2 22:17588658:G:A 22 17588658 A G 0.00104235 0.87878 120.973 3.9E-28 0.354615 22.4 IL17RA missense won N/A N/A N/A N/A N/A N/A rs531425523 56.0659 0.233387542404 IL17RA 0.0053 0.0000 0.0579 0.2601 blood_NEUTROPHIL_COUNT_v2 22:29091856:AG:A 22 29091856 A AG 0.00250404 0.876417 66.0479 4.4E-16 0.169695 35 CHEK2 frameshift won N/A N/A N/A N/A N/A N/A rs62237617 54.1072 0.839558043076 N/A N/A N/A N/A N/A blood_NEUTROPHIL_COUNT_v2 2:113539246:C:T 2 113539246 T C 0.00316033 0.917896 56.3758 6.0E-14 0.137284 22.7 IL1A missense lost rs555962557 0.992643617041 64.8409 0.863052148036 -0.129886 0.000765531787613 rs10169599 140.289 0.00132833278369 IL1A 0.0000 0.0000 0.0005 0.0000 blood_NEUTROPHIL_COUNT_v2 2:218999982:G:A 2 218999982 A G 0.00286519 0.93086 546.809 6.2E-121 -0.450628 22.6 CXCR2 missense lost rs16858768 0.988339983152 569.284 0.949320897561 0.453031 0.0186946398249 rs16858768 569.284 0.949320897561 CXCR2 0.0000 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 2:219000267:G:A 2 219000267 A G 0.000387874 0.851105 120.886 4.0E-28 -0.592923 24.9 CXCR2 missense won N/A N/A N/A N/A N/A N/A 2:219137341:G:A 114.841 0.943085707876 CXCR2 0.0002 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 4:74702809:G:GT 4 74702809 GT G 0.0074016 0.989239 138.214 6.5E-32 -0.134644 29.0 CXCL6 frameshift won rs9131 0.0228756717535 1164.65 0.00271475387089 0.0686226 99.5668170782 rs9131 1164.65 0.00271475387089 N/A N/A N/A N/A N/A blood_NEUTROPHIL_COUNT_v2 4:74964533:G:T 4 74964533 T G 3.34513e-05 0.939258 35.1034 3.1E-09 -0.967752 36 CXCL2 stop_gained lost 4:74702809:G:GT 0.00974892241565 138.214 0.00247601779216 -0.134644 28.5136373772 4:74702809:G:GT 138.214 0.00247601779216 CXCL2 0.0000 0.0000 0.0779 0.0004 blood_NEUTROPHIL_COUNT_v2 4:155489608:C:T 4 155489608 T C 0.00589916 0.942434 38.7458 4.8E-10 0.0821798 25.2 FGB missense won N/A N/A N/A N/A N/A N/A rs574396207 30.8401 0.302358116641 FGB 0.0001 0.0000 0.0018 0.0004 blood_NEUTROPHIL_COUNT_v2 5:176860948:G:A 5 176860948 A G 0.00310841 0.92204 29.8453 4.7E-08 0.107302 23.1 GRK6 missense lost rs79989845 0.000133972881787 32.2632 0.00012393255625 0.0236096 29.1583997315 rs79989845 32.2632 0.00012393255625 GRK6 0.0020 0.0000 0.0001 0.0000 blood_NEUTROPHIL_COUNT_v2 6:32008783:C:T 6 32008783 T C 0.00821009 0.900143 46.3774 9.8E-12 -0.089343 23.8 CYP21A2 missense lost 6:31940029:G:A 0.956518169156 50.5012 0.878411319696 -0.0851072 0.0224110289481 rs6916742 271.383 0.008221955625 CYP21A2 0.0018 0.0000 0.0000 0.0000 blood_NEUTROPHIL_COUNT_v2 6:32363893:G:A 6 32363893 A G 0.0088804 0.977753 36.4747 1.5E-09 -0.0646697 25.5 BTNL2 missense lost rs142406849 0.926760088735 48.4398 0.697841366161 0.0850426 0.0507909895462 rs6916742 271.383 0.011781799936 BTNL2 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_PLATELET_COUNT_v2 10:64927837:C:T 10 64927837 T C 0.00946673 0.940726 40.2023 2.3E-10 -0.0622303 26.6 JMJD1C missense lost rs185387098 0.869816788442 43.5923 0.802174592164 0.0606519 0.182414381332 10:65027610:A:T 1970.38 0.00660208251024 JMJD1C 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 11:58919922:G:GGCAGATACTT 11 58919922 GGCAGATACTT G 0.00719461 0.94492 41.8346 9.9E-11 0.0698514 31 FAM111A frameshift lost rs140003438 0.746239458043 42.2521 0.738865742329 -0.0786666 0.77546317726 rs28362951 141.536 0.00402401191201 N/A N/A N/A N/A N/A blood_PLATELET_COUNT_v2 11:64037726:C:G 11 64037726 G C 0.000313732 0.889847 31.0789 2.5E-08 0.287241 34 BAD missense lost 11:63978967:A:AC 1.09357048137 34.1342 0.995686661281 0.305505 0.0650193810414 rs12420070 101.114 0.00020597703361 BAD 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 11:116701354:G:A 11 116701354 A G 0.00224283 0.92045 44.4051 2.7E-11 0.125718 31 APOC3 splice_donor won rs7106641 0.00191187917721 129.912 0.00065349764496 -0.0249882 40.6067675836 11:116623213_TA_T 197.879 0.00026616617316 APOC3 0.0001 0.0000 0.1104 0.8914 blood_PLATELET_COUNT_v2 12:12022496:T:C 12 12022496 C T 0.00925102 0.96914 31.4063 2.1E-08 -0.050315 22.3 ETV6 missense lost rs2954934 0.00259916475613 34.2232 0.00238522838544 -0.0120409 28.2856179087 rs2954934 34.2232 0.00238522838544 ETV6 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 12:111856181:G:A 12 111856181 A G 0.00105958 0.940356 231.729 2.5E-52 0.426756 22.1 SH2B3 missense won 12:112866200_CT_C 0.00230881330831 1061.2 0.00050416415296 0.0645663 209.994809974 rs10744774 1653.85 0.000236667456 SH2B3 0.0012 0.0000 0.0181 0.0000 blood_PLATELET_COUNT_v2 12:111885295:G:A 12 111885295 A G 0.000489846 0.861631 277.684 2.4E-62 0.721403 32 SH2B3 missense won 12:111800258:G:A 0.00123727820233 1839.57 0.00018676775569 -0.0829459 258.492522086 12:111800258:G:A 1839.57 0.00018676775569 SH2B3 0.0001 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00199572 0.885884 788.135 2.0E-173 0.584981 32 SH2B3 missense lost rs769623925 0.960510797315 834.005 0.907683020176 -0.66524 0.313474462802 rs10744774 1653.85 0.00043927548921 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_PLATELET_COUNT_v2 12:111886074:C:T 12 111886074 T C 0.000219626 0.830257 39.6243 3.1E-10 0.3902 28.9 SH2B3 missense won rs11066272 0.00616371397766 1079.01 0.00022634901601 -0.061026 33.6467788264 rs11066272 1079.01 0.00022634901601 SH2B3 0.0001 0.0000 0.0008 0.0000 blood_PLATELET_COUNT_v2 12:111886075:G:A 12 111886075 A G 0.000259712 0.895854 31.5652 1.9E-08 0.31431 33 SH2B3 missense lost rs771031034 0.372569438705 34.5433 0.3404489104 -0.137816 4.79160082036 12:111800258:G:A 1839.57 0.00013188914649 SH2B3 0.0005 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 12:111902514:G:A 12 111902514 A G 0.00198952 0.921516 35.6969 2.3E-09 -0.119879 26.8 ATXN2 missense lost rs527898634 0.993928288851 46.497 0.763063396225 0.141463 0.000330000185482 rs7137828 2900.8 0.00166124717056 ATXN2 0.0000 0.0000 0.0986 0.0000 blood_PLATELET_COUNT_v2 12:112167753:G:A 12 112167753 A G 0.00552211 0.971607 64.5237 9.5E-16 -0.0933581 25.1 ACAD10 missense lost 12:111953704:G:A 1.00810904966 517.638 0.125661033169 -0.101796 0.0010564371499 rs7137828 2900.8 0.00482922145476 ACAD10 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 12:112184086:G:A 12 112184086 A G 0.00202423 0.911388 93.5473 4.0E-22 0.198299 28.2 ACAD10 missense lost rs566096105 0.972135457834 195.167 0.465963238225 -0.455283 0.0184157758317 rs10744774 1653.85 0.00044168486569 ACAD10 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 12:112673047:T:A 12 112673047 A T 0.00692361 0.996032 55.4048 9.8E-14 -0.0786564 20.7 HECTD4 missense lost rs112768822 0.986588741061 56.2426 0.971892335716 0.0785439 0.00250814979172 rs7137828 2900.8 0.00671177116516 HECTD4 0.0173 0.0039 0.0000 0.0000 blood_PLATELET_COUNT_v2 12:112681251:C:T 12 112681251 T C 0.00356459 0.922717 40.4047 2.1E-10 -0.0944591 28.5 HECTD4 missense lost rs545837065 0.972148222857 42.7299 0.919247583076 0.0953121 0.00794675488479 rs7137828 2900.8 0.00298160773681 HECTD4 0.0075 0.0000 0.0004 0.0000 blood_PLATELET_COUNT_v2 15:65153716:G:A 15 65153716 A G 0.000262507 0.943504 36.4755 1.5E-09 -0.315121 29.8 AC069368.3 missense won rs12914525 0.00113193501058 90.1039 0.00045822539844 -0.0173832 34.0624068073 rs12914525 90.1039 0.00045822539844 PLEKHO2 0.0027 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 16:88788037:G:A 16 88788037 A G 0.000969012 0.953717 52.0268 5.5E-13 -0.220456 31 PIEZO1 missense won 16:88779952:C:CCT 0.00922364545405 60.9381 0.00787482309604 0.0234862 42.5133885943 rs17175830 259.984 0.00018890853136 PIEZO1 0.0170 0.0000 0.0118 0.0000 blood_PLATELET_COUNT_v2 17:4836485:C:T 17 4836485 T C 4.56449e-05 0.834421 93.9177 3.3E-22 -1.46654 35 GP1BA stop_gained won 17:4794493:G:A 0.00118137312054 111.216 0.00099762485904 -0.0438125 87.5725408753 17:4796441:G:C 162.698 0.00050661456561 GP1BA 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 17:4837743:CTAATG:C 17 4837743 C CTAATG 0.000932768 0.820471 74.9525 4.8E-18 -0.262587 34 GP1BA frameshift won rs2586527 0.00313288959614 91.6969 0.00256080529936 -0.0206791 66.7968020214 rs7221186 226.676 0.00010363036401 N/A N/A N/A N/A N/A blood_PLATELET_COUNT_v2 17:16852187:A:G 17 16852187 G A 0.00697138 0.947032 167.624 2.4E-38 -0.140763 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs568982652 113.261 0.645350335569 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 17:42453538:G:T 17 42453538 T G 0.000846635 0.877657 229.9 6.3E-52 -0.497078 27.1 ITGA2B missense won N/A N/A N/A N/A N/A N/A 17:42534237_AT_A 180.916 0.00083459165449 ITGA2B 0.0916 0.0000 0.0273 0.0000 blood_PLATELET_COUNT_v2 17:42457494:C:T 17 42457494 T C 0.00020553 0.801925 33.8645 5.9E-09 -0.424695 23.2 ITGA2B missense lost rs534964809 0.719535277688 38.1249 0.639128297025 0.507935 0.779790111611 17:42530846_TGTAG_T 173.23 0.00012033870601 ITGA2B 0.0057 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 17:45380203:C:T 17 45380203 T C 0.00130808 0.83385 31.5045 2.0E-08 -0.142122 25.0 ITGB3 missense lost rs547430519 0.517991160138 44.8586 0.363788716201 0.284235 2.4749653323 rs72827839 75.1709 0.00050932816489 RP11-290H9.2 0.0000 0.0000 0.0004 0.0000 blood_PLATELET_COUNT_v2 19:10464843:G:A 19 10464843 A G 0.00778005 0.919201 51.4466 7.4E-13 -0.0707289 33 TYK2 missense lost rs113906245 0.749577323469 52.9917 0.727721600356 0.0755617 0.926792467065 rs12462978 75.9739 0.00328267118916 TYK2 0.0014 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 19:16280544:T:C 19 16280544 C T 0.000627552 0.831843 67.2996 2.3E-16 -0.307059 25.3 CIB3 missense lost rs536829453 1.14746382157 356.595 0.216558998881 0.333882 0.341146152076 19:16206012:C:T 1300.13 0.025164745956 CIB3 0.1365 0.0707 0.0000 0.0000 blood_PLATELET_COUNT_v2 19:39226928:G:A 19 39226928 A G 0.00898814 0.956287 35.6081 2.4E-09 0.0655317 20.5 CAPN12 missense lost 19:39192116:G:A 0.872139083785 66.6874 0.4656834081 0.0586512 0.155655203208 rs36125859 163.887 0.136484435844 CAPN12 0.1233 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 19:55697712:G:A 19 55697712 A G 0.00272019 0.871871 89.0382 3.9E-21 -0.17206 41 PTPRH stop_gained won N/A N/A N/A N/A N/A N/A 19:55693244:T:C 72.3088 0.010277498884 PTPRH 0.0533 0.0577 0.0000 0.0000 blood_PLATELET_COUNT_v2 19:58423509:C:A 19 58423509 A C 0.00489813 0.966885 31.2313 2.3E-08 -0.0798225 35 ZNF417 stop_gained lost rs3764531 0.00200514101801 96.1117 0.00065156646564 0.0189362 28.496922826 19:58931895_TA_T 115.77 0.00053601973441 ZNF417 0.0001 0.6034 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:31211894:G:A 1 31211894 A G 0.00952761 0.872715 46.4378 9.5E-12 0.0671522 21.7 LAPTM5 missense lost rs138971241 0.860676288815 49.0712 0.8144882001 -0.0694718 0.242566550127 rs74340846 84.5632 0.174662977329 LAPTM5 0.0011 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:43803899:C:T 1 43803899 T C 0.000311387 0.907166 50.0911 1.5E-12 0.36071 22.0 MPL missense won rs376070354 0.000341235810414 75.8985 0.00022520704761 -0.0203523 48.2575702616 rs376070354 75.8985 0.00022520704761 MPL 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:43804305:G:C 1 43804305 C G 0.00053509 0.907042 159.177 1.7E-36 0.491202 26.0 MPL missense lost 1:43892277:A:C 1.01430950656 161.829 0.997687338649 0.495436 0.00809056614752 1:43892277:A:C 161.829 0.997687338649 MPL 0.0278 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:43804375:CT:C 1 43804375 C CT 0.000217911 0.915383 43.7002 3.8E-11 0.42207 28.7 MPL frameshift won 1:45939469_AT_A 0.000158146719418 48.2012 0.00014337907081 -0.0138355 42.6079950839 1:45939469_AT_A 48.2012 0.00014337907081 N/A N/A N/A N/A N/A blood_PLATELET_COUNT_v2 1:43814627:G:A 1 43814627 A G 6.97765e-05 0.946762 46.3623 9.8E-12 0.742133 39 MPL stop_gained won rs11579411 0.000422543305935 60.9274 0.00032153151969 -0.0273633 44.4758563512 rs77506398 84.5218 0.00022947402256 MPL 0.0023 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:43826794:G:A 1 43826794 A G 0.00666945 0.975349 35.8242 2.2E-09 0.0631116 22.4 CDC20 missense lost rs193018877 1.03478415534 37.2421 0.995387331481 -0.0643661 0.0106517953496 rs785475 163.453 0.00010384832836 CDC20 0.0023 0.0007 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:44085173:T:C 1 44085173 C T 0.000125665 0.840354 34.4568 4.4E-09 0.504257 24.7 PTPRF missense lost rs539707895 0.981424909578 148.972 0.227000790916 -0.482701 0.00300012080872 1:43892277:A:C 161.829 0.204219936649 PTPRF 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 1:115130508:A:G 1 115130508 G A 0.00565043 0.909475 33.6173 6.7E-09 -0.0694422 29.0 DENND2C missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A DENND2C 0.0010 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 1:115142870:G:A 1 115142870 A G 0.0072839 0.95881 34.6322 4.0E-09 -0.0614944 31 DENND2C missense won N/A N/A N/A N/A N/A N/A rs566716589 32.7031 0.552720876304 DENND2C 0.0202 0.0000 0.0009 0.0188 blood_PLATELET_COUNT_v2 1:156877520:A:G 1 156877520 G A 0.00115391 0.855139 38.7512 4.8E-10 0.173328 23.2 PEAR1 missense lost rs72700708 0.0536809283043 40.2446 0.051688931904 -0.0469053 22.8747569041 rs11264534 125.907 0.00036081382401 PEAR1 0.0000 0.0000 0.1181 0.5456 blood_PLATELET_COUNT_v2 1:166829517:G:A 1 166829517 A G 0.000345299 0.826126 41.3399 1.3E-10 -0.315652 40 TADA1 stop_gained won N/A N/A N/A N/A N/A N/A rs540331101 33.7809 0.490358465536 TADA1 0.0198 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 20:30253819:C:T 20 30253819 T C 5.86914e-05 0.978061 40.5333 1.9E-10 -0.767223 24.9 BCL2L1 missense won rs535669839 0.000330051988036 63.9033 0.00020934906721 0.0168097 39.0739141795 rs10875494 74.9398 0.00010690526025 BCL2L1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57598607:C:T 20 57598607 T C 8.93946e-05 0.970822 122.437 1.9E-28 -1.09803 36 TUBB1 stop_gained won rs151346 0.000183384012601 193.878 0.00011580988225 0.0253036 119.143385115 rs151349 200.458 0.00010914816676 TUBB1 0.0003 0.0000 0.0000 0.0068 blood_PLATELET_COUNT_v2 20:57598808:G:A 20 57598808 A G 0.00133716 0.96877 863.144 1.0E-189 -0.729523 24.8 TUBB1 missense won N/A N/A N/A N/A N/A N/A rs113703016 694.065 0.774264485929 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 20:57598882:C:T 20 57598882 T C 8.81385e-05 0.933294 94.0906 3.0E-22 -0.902163 41 TUBB1 stop_gained won rs77124424 0.0579761077888 247.434 0.0220463104 0.228875 54.2349078208 rs77124424 247.434 0.0220463104 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 20:57598910:C:T 20 57598910 T C 4.23084e-05 0.761966 36.3562 1.6E-09 -0.888212 26.9 TUBB1 missense won 20:57176649_G_T 0.000511815759908 52.9381 0.00035149875289 0.593607 34.7298099315 20:57176649_G_T 52.9381 0.00035149875289 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57598918:G:A 20 57598918 A G 5.68578e-05 0.907681 70.607 4.4E-17 -1.11276 26.5 TUBB1 missense won 20:57832099:G:A 0.0011892481734 89.9188 0.00093383414569 -0.036274 65.8211369954 20:57832099:G:A 89.9188 0.00093383414569 TUBB1 0.0004 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57598966:C:T 20 57598966 T C 6.55628e-05 0.892216 65.3333 6.3E-16 -0.908453 28.5 TUBB1 missense won 20:57556488:C:T 0.000796194351186 183.336 0.00028373044249 -0.035326 61.6983095221 20:57556488:C:T 183.336 0.00028373044249 TUBB1 0.0012 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57599032:A:G 20 57599032 G A 2.72124e-05 0.755746 47.3584 5.9E-12 -1.45138 25.6 TUBB1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TUBB1 0.0111 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57599106:T:A 20 57599106 A T 2.42197e-05 0.928852 35.7435 2.3E-09 -1.1492 35 TUBB1 stop_gained lost rs11570256 0.0236149282705 205.485 0.00410774600889 0.187753 25.60206605 rs11570256 205.485 0.00410774600889 TUBB1 0.0016 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57599203:C:T 20 57599203 T C 0.000251933 0.925563 408.207 9.0E-91 -1.19184 33 TUBB1 missense won N/A N/A N/A N/A N/A N/A 20:57570854:G:A 301.341 0.00012416867761 TUBB1 0.0008 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 20:57599342:C:T 20 57599342 T C 0.000283769 0.915176 68.0735 1.6E-16 -0.445647 24.5 TUBB1 missense lost 20:57556330:G:GGGAGGGCATGGC 0.67676270121 73.4075 0.627587177616 -0.35619 2.14097528969 20:57597970:A:C 426.897 0.00516407518225 TUBB1 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 22:19711776:T:C 22 19711776 C T 2.16765e-05 0.777716 61.5212 4.4E-15 -1.75217 25.3 GP1BB missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A GP1BB 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 22:21235389:A:G 22 21235389 G A 0.00500239 0.993589 29.845 4.7E-08 0.068736 25.3 SNAP29 missense lost rs117143977 1.00127491041 30.3031 0.986138372025 -0.0703739 1.2119765537e-05 rs191152350 33.4088 0.938110410721 SNAP29 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 22:29091856:AG:A 22 29091856 A AG 0.00249823 0.876417 41.7768 1.0E-10 0.127384 35 CHEK2 frameshift won rs5763081 0.0026361409477 45.7962 0.00240477448225 -0.0144733 37.5970066992 22:29695929:T:G 95.7242 0.00014547978225 N/A N/A N/A N/A N/A blood_PLATELET_COUNT_v2 2:24245713:C:G 2 24245713 G C 0.00489397 0.972585 40.1382 2.4E-10 -0.0810346 26.0 MFSD2B missense lost rs113362373 0.0539595297185 70.2692 0.030822015844 0.0216192 23.6564804113 rs200742198 77.8529 0.027596851129 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 2:109276179:G:A 2 109276179 A G 0.000652627 0.919751 34.024 5.4E-09 0.212971 25.4 LIMS1 missense won rs12998958 0.00171048424261 62.2253 0.00093527095684 -0.0147829 31.2678682672 rs2118446 64.5642 0.00074898005625 LIMS1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 2:113496453:G:A 2 113496453 A G 0.00929922 0.983872 79.6502 4.5E-19 0.0807931 24.7 CKAP2L missense won rs55709272 0.00514887973005 81.0499 0.00505996059556 -0.0148591 68.6295984232 2:113841030:A:G 91.2905 0.00219474447361 NT5DC4 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 2:160673358:G:A 2 160673358 A G 0.000509556 0.811765 30.663 3.1E-08 0.253793 33 LY75-CD302 missense lost rs10489999 0.00308794478113 55.4284 0.001708251561 -0.0220634 27.3498440399 rs10489999 55.4284 0.001708251561 LY75 0.0000 0.0000 0.0000 0.0552 blood_PLATELET_COUNT_v2 2:160714958:C:T 2 160714958 T C 0.00224045 0.964578 78.4239 8.3E-19 0.174776 36 LY75-CD302 stop_gained won rs78166224 0.0138556569153 83.9543 0.012942930289 -0.0269123 61.0479515762 rs62175229 188.354 0.00279520517809 LY75 0.0081 0.0024 0.0000 0.0000 blood_PLATELET_COUNT_v2 2:160735174:C:T 2 160735174 T C 0.00248917 0.952394 43.3922 4.5E-11 0.12329 23.7 LY75-CD302 missense lost rs181443210 0.961092080645 46.7535 0.891995247025 -0.126767 0.0167495230725 rs138674166 129.816 0.00020233355536 LY75 0.0000 0.0000 0.0005 0.1076 blood_PLATELET_COUNT_v2 3:124303696:C:T 3 124303696 T C 0.00206917 0.874463 60.1682 8.7E-15 0.161053 40 KALRN stop_gained won rs34605102 0.0031257366338 114.098 0.00164831940025 0.0193549 53.6284678747 rs3804749 446.237 0.000141514816 N/A N/A N/A N/A N/A blood_PLATELET_COUNT_v2 3:128780764:A:G 3 128780764 G A 0.000827193 0.9345 408.323 8.5E-91 -0.651052 23.2 GP9 missense won N/A N/A N/A N/A N/A N/A rs556451147 254.248 0.482320527049 GP9 0.2665 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 3:184008878:T:A 3 184008878 A T 0.00403431 0.953021 36.3353 1.7E-09 0.088377 23.5 ECE2 missense lost 3:184100587:G:A 0.587233202418 78.282 0.272569614724 0.0761343 1.98428342762 3:184090266:C:T 1019.25 0.00256893881409 ECE2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 3:184090891:C:T 3 184090891 T C 1.80182e-05 0.713151 34.0408 5.4E-09 -1.27965 26.7 THPO missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A THPO 0.0025 0.0000 0.0166 0.0000 blood_PLATELET_COUNT_v2 4:2941317:G:A 4 2941317 A G 0.00429779 0.954914 39.752 2.9E-10 -0.095093 21.6 NOP14 missense lost 4:2941720_CCAGA_C 0.989272307922 43.9788 0.894193401924 0.0931793 0.00114987466977 rs13108218 102.031 0.00135943377025 NOP14 0.0001 0.0000 0.0252 0.0000 blood_PLATELET_COUNT_v2 5:75866423:C:T 5 75866423 T C 0.000668251 0.910187 75.5113 3.6E-18 -0.30351 41 IQGAP2 stop_gained won rs10647961 0.0151542204732 469.393 0.00243786100009 -0.0499304 58.0643583592 rs250721 469.581 0.00242326799289 IQGAP2 0.0904 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 5:75932944:G:A 5 75932944 A G 0.000120772 0.864993 32.1776 1.4E-08 -0.49078 40 IQGAP2 stop_gained won rs10078999 0.000695568338682 120.54 0.00018567877696 -0.0190978 30.5027015116 rs10078999 120.54 0.00018567877696 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 5:75960968:G:C 5 75960968 C G 0.00590622 0.930086 235.32 4.1E-53 -0.191984 27.7 IQGAP2 missense won rs250721 0.0403955276082 469.581 0.020243313841 -0.0496617 150.233642556 rs250721 469.581 0.020243313841 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 5:75960989:T:C 5 75960989 C T 0.000227881 0.67766 36.6043 1.4E-09 -0.420553 26.8 IQGAP2 missense lost rs548496802 0.424995999857 306.124 0.050818234041 0.252605 4.4350375597 5:75996909:G:A 1239.65 0.00321859924929 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:31605016:T:C 6 31605016 C T 0.00828517 0.99288 63.8212 1.4E-15 0.0782203 29.9 PRRC2A missense lost rs41273248 0.967510702045 72.804 0.848136009249 -0.0834096 0.0171209606526 rs210146 1854.21 0.00065607187321 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_PLATELET_COUNT_v2 6:32008783:C:T 6 32008783 T C 0.00821623 0.900143 50.7121 1.1E-12 -0.070758 23.8 CYP21A2 missense lost 6:31748110_ACTGT_A 1.01128293118 76.5677 0.669790017649 0.0723447 0.00160492863891 rs68138249 669.437 0.00037983281449 CYP21A2 0.0018 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:32151458:G:A 6 32151458 A G 0.00535789 0.979931 31.2136 2.3E-08 0.0675067 26.1 AGER missense lost 6:31848280:G:A 0.999716286403 57.4502 0.543161630025 0.0713731 6.28211357659e-07 rs511515 2610.57 0.00027829913329 AGER 0.0865 0.0000 0.0047 0.0000 blood_PLATELET_COUNT_v2 6:32362521:C:A 6 32362521 A C 0.00470208 0.996999 35.3256 2.8E-09 0.0753871 57 BTNL2 stop_gained lost rs190367303 1.00035985171 35.4484 0.996894414916 -0.0751157 1.14340102353e-06 rs210146 1854.21 0.000147088384 BTNL2 0.0057 0.0000 0.0032 0.3767 blood_PLATELET_COUNT_v2 6:32364052:C:T 6 32364052 T C 0.00471478 0.997326 35.0856 3.2E-09 0.0749442 26.2 BTNL2 missense lost 6:32363973:C:T 1.0 35.0856 1.0 0.0749442 0.0 rs210146 1854.21 0.00014226287076 BTNL2 0.0679 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:32370927:G:A 6 32370927 A G 0.00471419 0.997188 35.0648 3.2E-09 0.0749308 24.1 BTNL2 missense lost rs117381344 1.00008555589 35.0678 1.0 -0.0747111 6.41641690463e-08 rs210146 1854.21 0.00014226287076 BTNL2 0.0111 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:32825089:C:T 6 32825089 T C 0.00121524 0.967943 57.2615 3.8E-14 0.201762 25.3 PSMB9 missense lost rs569330326 0.436482236261 65.07 0.384103697121 -0.153013 6.59344360429 rs511515 2610.57 0.00040114481796 PSMB9 0.0238 0.0013 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:33541983:T:A 6 33541983 A T 0.000309104 0.903841 40.6356 1.8E-10 0.325544 25.0 BAK1 stop_gained lost rs9380371 0.0314339207381 1503.59 0.00084952429156 -0.0792514 27.5038662957 rs511515 2610.57 0.000116834481 BAK1 0.0001 0.0000 0.0005 0.0000 blood_PLATELET_COUNT_v2 6:36507854:T:A 6 36507854 A T 0.000382327 0.975544 31.043 2.5E-08 0.252613 22.2 STK38 missense lost rs7747978 0.0847297965898 98.7781 0.026628038761 -0.0755395 15.6010363526 rs3818528 468.698 0.00010944298225 STK38 0.0000 0.0000 0.0001 0.0001 blood_PLATELET_COUNT_v2 6:36698471:G:A 6 36698471 A G 0.00507222 0.976836 31.5431 2.0E-08 0.0741442 32 RAB44 missense lost rs138886395 1.00758300455 76.7973 0.413846469481 -0.0993206 0.000451736360249 rs116957783 149.214 0.205090331161 RAB44 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:43411992:A:G 6 43411992 G A 0.00330022 0.876088 37.7207 8.2E-10 -0.102321 21.5 ABCC10 missense lost rs144041302 0.751591532588 40.9725 0.6919411489 0.111998 0.667805590181 rs757592196 43.8096 0.175001662224 ABCC10 0.0001 0.0000 0.0002 0.0000 blood_PLATELET_COUNT_v2 6:109774960:C:T 6 109774960 T C 0.00430188 0.944229 37.1678 1.1E-09 -0.08601 32 MICAL1 missense lost rs112273618 0.0184460732386 153.321 0.00447166377025 -0.0217312 27.757412198 rs1008084 166.567 0.00351925392289 MICAL1 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 6:161134124:A:G 6 161134124 G A 0.000601463 0.955272 57.8177 2.9E-14 0.303943 23.3 PLG missense won N/A N/A N/A N/A N/A N/A rs528980492 40.0354 0.673448368321 PLG 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 7:100319633:G:A 7 100319633 A G 0.00534067 0.826534 52.2599 4.9E-13 0.0900725 23.9 EPO missense lost 7:99639187:G:A 0.116226135829 74.3573 0.081686212864 0.0400381 22.7010236276 7:100240296:G:A 216.239 0.00254874532201 EPO 0.0020 0.0000 0.0001 0.1020 blood_PLATELET_COUNT_v2 8:22885843:C:T 8 22885843 T C 0.00084917 0.84979 30.5733 3.2E-08 0.18095 22.6 TNFRSF10B splice_donor lost rs71546824 0.00115273419557 93.3035 0.00037772311201 -0.0202143 28.5324972248 rs4592028 105.734 0.00029128590241 TNFRSF10B 0.0001 0.0000 0.1188 0.9908 blood_PLATELET_COUNT_v2 9:271626:G:T 9 271626 T G 0.00090381 0.92625 40.0328 2.5E-10 -0.200567 34 DOCK8 splice_acceptor won rs752379926 0.0121705361275 232.671 0.00209403251236 0.0346214 31.6871714077 rs10813156 258.889 0.001079319609 DOCK8 0.0755 0.9539 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:4576045:T:C 9 4576045 C T 0.00350322 0.933722 41.6977 1.1E-10 0.09585 23.8 SLC1A1 missense lost rs189782850 0.802196664925 68.8391 0.485912161476 -0.106945 0.45400541114 rs12005199 3151.84 0.00227725566436 SLC1A1 0.0581 0.0000 0.0001 0.0000 blood_PLATELET_COUNT_v2 9:4833154:G:A 9 4833154 A G 0.00923014 0.971388 30.0665 4.2E-08 0.0501855 27.2 RCL1 missense lost 9:4763176:C:T 0.696370828606 3076.11 0.00680646450169 -0.0996298 0.823644763534 9:4763176:C:T 3076.11 0.00680646450169 RCL1 0.0005 0.0288 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:5055751:G:A 9 5055751 A G 4.88713e-05 0.844433 56.7316 5.0E-14 1.03452 31 JAK2 missense won rs10974724 0.000778041742951 211.989 0.00020821624209 -0.0377497 53.610865172 rs10974724 211.989 0.00020821624209 JAK2 0.0001 0.0000 0.0001 0.0037 blood_PLATELET_COUNT_v2 9:5081828:G:C 9 5081828 C G 0.00104457 0.937121 244.769 3.6E-55 0.443515 21.9 JAK2 missense won rs12005199 0.0144363191626 3151.84 0.001121111289 -0.111481 189.483968349 rs12005199 3151.84 0.001121111289 JAK2 0.0001 0.0000 0.0000 0.0001 blood_PLATELET_COUNT_v2 9:5126343:G:A 9 5126343 A G 0.00556262 0.935982 228.484 1.3E-51 0.182111 24.8 JAK2 missense won rs692502 0.0146937861312 2647.96 0.00126787981329 -0.093307 176.44858079 rs12005199 3151.84 0.00056904671209 JAK2 0.0022 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:135781401:C:G 9 135781401 G C 7.5427e-05 0.595221 32.1167 1.5E-08 -0.818802 22.8 TSC1 missense lost 9:135864513:C:T 0.296348488372 1803.53 0.00527728149601 -0.434496 6.66712186674 9:135864513:C:T 1803.53 0.00527728149601 TSC1 0.0007 0.0000 0.0019 0.0000 blood_PLATELET_COUNT_v2 9:135864458:C:A 9 135864458 A C 0.000160229 0.916116 36.7105 1.4E-09 -0.447437 24.6 GFI1B missense won rs3205136 0.00128973933585 129.56 0.00036544439556 0.0370018 34.12108293 9:136131022:C:T 143.925 0.00032613831649 GFI1B 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:135864485:G:A 9 135864485 A G 6.51661e-05 0.781542 69.1923 8.9E-17 -0.974803 27.1 GFI1B missense won N/A N/A N/A N/A N/A N/A rs3011264 45.5573 0.00010111106916 GFI1B 0.0383 0.0005 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:135864488:G:A 9 135864488 A G 7.56297e-05 0.837678 126.955 1.9E-29 -1.19203 26.7 GFI1B missense won 9:136131022:C:T 0.000893698287812 143.925 0.00078832354441 -0.0394996 119.477874107 rs2506698 157.986 0.00010166285584 GFI1B 0.0262 0.0006 0.0000 0.0000 blood_PLATELET_COUNT_v2 9:135864506:G:A 9 135864506 A G 9.59399e-05 0.688071 37.3997 9.6E-10 -0.619797 23.2 GFI1B missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A GFI1B 0.0013 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_PLATELET_DISTRIB_WIDTH_v2 10:101295456:T:G 10 101295456 G T 0.00837262 0.978121 38.792 4.7E-10 0.0651855 33 NKX2-3 missense won N/A N/A N/A N/A N/A N/A 10:98969937_CA_C 32.8803 0.00013255607689 NKX2-3 0.0000 0.0000 0.0021 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 11:116661656:G:A 11 116661656 A G 0.000257984 0.934111 50.8047 1.0E-12 0.44148 37 APOA5 stop_gained won rs180327 0.00217498482822 257.647 0.00042887924836 0.0311676 46.1764690336 rs180327 257.647 0.00042887924836 APOA5 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 11:116701354:G:A 11 116701354 A G 0.00224087 0.92045 79.6893 4.4E-19 -0.176819 31 APOC3 splice_donor won rs61905084 0.012018896926 119.963 0.00798394073841 0.0260332 63.1742852434 11:116648917:C:G 871.858 0.00023723084529 APOC3 0.0001 0.0000 0.1104 0.8914 blood_PLATELET_DISTRIB_WIDTH_v2 12:49170029:A:G 12 49170029 G A 0.00290817 0.911977 39.5209 3.2E-10 0.119146 25.8 ADCY6 missense lost 12:49312749:G:A 1.02136725452 70.0687 0.576082518001 0.175324 0.00446335245901 rs7958679 1784.22 0.014713447401 ADCY6 0.0000 0.0000 0.0001 0.0004 blood_PLATELET_DISTRIB_WIDTH_v2 12:49579290:A:T 12 49579290 T A 0.00781682 0.945757 136.536 1.5E-31 0.12969 20.9 TUBA1A missense lost 12:49667057:TTTTG:T 0.976578469449 143.402 0.929820489984 0.128314 0.0189473688283 rs7958679 1784.22 0.086396020624 TUBA1A 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 15:65153716:G:A 15 65153716 A G 0.000262273 0.943504 59.7297 1.1E-14 0.445889 29.8 AC069368.3 missense won rs191649501 0.0432006706449 79.032 0.032649598864 -0.0945263 37.4807003428 rs28667843 285.153 0.00011407094416 PLEKHO2 0.0027 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 15:65153746:G:A 15 65153746 A G 0.000100285 0.897561 30.2812 3.7E-08 0.497535 31 AC069368.3 missense lost 15:63618402:G:A 0.00229782114396 33.5905 0.00207144227161 0.0551819 27.4476861814 rs11634670 146.348 0.00010097235225 PLEKHO2 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 16:85696635:A:T 16 85696635 T A 0.0071325 0.961994 42.1485 8.5E-11 -0.0675467 26.1 GSE1 missense won rs148610400 0.0203184788866 206.091 0.00415541390625 -0.0266632 30.9889544045 16:85704296_AT_A 218.109 0.003744828025 GSE1 0.0000 0.0007 0.0009 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 17:4836485:C:T 17 4836485 T C 4.56087e-05 0.834421 49.3167 2.2E-12 1.09184 35 GP1BA stop_gained won 17:4794493:G:A 0.00250668294658 124.035 0.0009966649 0.0477304 44.5020641127 rs66863998 242.712 0.00034359071044 GP1BA 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 17:4837743:CTAATG:C 17 4837743 C CTAATG 0.000932427 0.820471 81.6178 1.7E-19 0.281101 34 GP1BA frameshift won rs2586528 0.0051066096627 228.449 0.00182443453956 0.0315434 70.3696851114 rs72835066 341.787 0.00010178388544 N/A N/A N/A N/A N/A blood_PLATELET_DISTRIB_WIDTH_v2 17:16852187:A:G 17 16852187 G A 0.00696643 0.947032 36.1588 1.8E-09 0.0638151 26.1 TNFRSF13B missense lost rs568982652 0.64699279418 36.265 0.6450981124 -0.0673099 1.38399790117 rs58887677 52.0354 0.00457311357504 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 17:33884124:C:T 17 33884124 T C 0.00194119 0.925583 86.8622 1.2E-20 -0.193905 23.6 SLFN14 missense won rs148561432 0.0517080598918 155.515 0.028881303025 0.0533396 51.8497786801 rs321598 323.069 0.00079527948049 SLFN14 0.0334 0.0000 0.0002 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 17:42453538:G:T 17 42453538 T G 0.000846279 0.877657 87.5632 8.2E-21 0.310872 27.1 ITGA2B missense won N/A N/A N/A N/A N/A N/A rs375071427 57.4001 0.00020936932416 ITGA2B 0.0916 0.0000 0.0273 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 17:74383107:CG:C 17 74383107 C CG 0.00361849 0.973727 35.9684 2.0E-09 0.0907678 35 SPHK1 frameshift lost rs144887234 0.798285694467 37.505 0.765579500676 -0.0871512 0.408205091459 rs35976162 89.0369 0.00723625838244 N/A N/A N/A N/A N/A blood_PLATELET_DISTRIB_WIDTH_v2 18:21116700:A:G 18 21116700 G A 0.000820398 0.880176 37.9162 7.4E-10 0.198625 24.1 NPC1 missense won 18:20715656:G:A 0.00313602757514 413.281 0.00028771283641 0.0370007 33.7884731784 18:20715656:G:A 413.281 0.00028771283641 NPC1 0.0020 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 18:67531573:G:A 18 67531573 A G 0.00221806 0.970617 33.7648 6.2E-09 -0.114008 26.7 CD226 missense lost rs7241191 0.066292114159 638.418 0.00350607278641 0.0474951 18.6161216433 rs34086233 859.395 0.00214781268025 CD226 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 19:12802009:T:C 19 12802009 C T 0.0019075 0.791141 34.9254 3.4E-09 -0.132129 24.8 FBXW9 missense lost rs549653211 0.78451687608 36.0446 0.7601572969 0.149963 0.456046462176 rs559333954 42.239 0.00019823795209 FBXW9 0.0001 0.0000 0.0183 0.0006 blood_PLATELET_DISTRIB_WIDTH_v2 19:16280544:T:C 19 16280544 C T 0.000628147 0.831843 46.1873 1.1E-11 0.272519 25.3 CIB3 missense lost rs545345349 1.10756790927 89.7931 0.569704924944 -0.402347 0.126870182608 19:16206012:C:T 1126.83 0.025220933721 CIB3 0.1365 0.0707 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 1:115130508:A:G 1 115130508 G A 0.00564875 0.909475 207.423 5.0E-47 -0.184736 29.0 DENND2C missense won 1:113242488:C:T 0.000456083179394 456.837 0.00020708073409 0.040295 198.658107808 rs6700673 611.264 0.000109935225 DENND2C 0.0010 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 1:115142870:G:A 1 115142870 A G 0.00727976 0.95881 157.755 3.5E-36 -0.133555 31 DENND2C missense won N/A N/A N/A N/A N/A N/A rs12131807 118.554 0.00369102421444 DENND2C 0.0202 0.0000 0.0009 0.0188 blood_PLATELET_DISTRIB_WIDTH_v2 1:115144142:T:C 1 115144142 C T 0.000272741 0.8826 32.733 1.1E-08 0.287252 22.5 DENND2C missense lost rs566426285 0.00499083411343 90.4596 0.00180594401296 -0.0272937 28.2714646877 rs12131807 118.554 0.00045111636025 DENND2C 0.0008 0.0000 0.0006 0.0056 blood_PLATELET_DISTRIB_WIDTH_v2 1:156877520:A:G 1 156877520 G A 0.00115272 0.855139 35.266 2.9E-09 -0.155283 23.2 PEAR1 missense won rs11264583 0.000353651929064 78.0148 0.00015986567844 -0.0222504 33.9520728011 rs11264583 78.0148 0.00015986567844 PEAR1 0.0000 0.0000 0.1181 0.5456 blood_PLATELET_DISTRIB_WIDTH_v2 1:166829517:G:A 1 166829517 A G 0.000345005 0.826126 50.6547 1.1E-12 0.338323 40 TADA1 stop_gained won N/A N/A N/A N/A N/A N/A rs566024347 35.3041 0.591227201569 TADA1 0.0198 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 1:171505241:C:A 1 171505241 A C 0.00584396 0.918836 68.9657 1.0E-16 0.102932 23.5 PRRC2C missense lost rs532436084 0.957245813897 71.5452 0.9227331481 -0.103046 0.0322082318145 rs2057301 2954.37 0.00096124181521 PRRC2C 0.0030 0.0000 0.0035 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 1:171605478:G:A 1 171605478 A G 0.00131625 0.976138 34.1498 5.1E-09 0.142179 38 MYOC stop_gained lost rs56125409 0.48609102761 2380.86 0.00697223330001 -0.136305 3.13107412148 rs2038479 4802.13 0.00024895475089 MYOC 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 1:172348254:A:G 1 172348254 G A 0.000360198 0.854963 35.257 2.9E-09 0.30903 22.0 DNM3 missense lost rs147953317 0.320068584406 95.9902 0.117560522641 -0.193786 6.64864165191 rs2057301 2954.37 0.00028896260121 DNM3 0.0000 0.0000 0.0016 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598607:C:T 20 57598607 T C 8.93151e-05 0.970822 338.202 1.6E-75 1.81285 36 TUBB1 stop_gained won rs4812066 0.00091680674647 380.007 0.00081594779904 -0.0621427 318.03135308 rs6123835 494.781 0.00019042344036 TUBB1 0.0003 0.0000 0.0000 0.0068 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598808:G:A 20 57598808 A G 0.0013282 0.96877 3334.27 1.3E-726 1.46873 24.8 TUBB1 missense won rs773385727 0.0128813757773 4304.42 0.00997811199025 -0.186031 2620.36637714 rs773385727 4304.42 0.00997811199025 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598813:G:A 20 57598813 A G 2.9509e-05 0.896395 31.0088 2.6E-08 0.97594 24.7 TUBB1 missense lost rs73618656 0.00953853656609 910.821 0.00032473842025 -0.10897 25.2476028903 rs75655984 976.735 0.00027130701796 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598882:C:T 20 57598882 T C 8.24674e-05 0.933294 301.682 1.4E-67 1.78302 41 TUBB1 stop_gained won rs77124424 0.0439915014405 661.049 0.020076339481 -0.37734 188.402967089 rs2043671 2586.9 0.00417181642816 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598910:C:T 20 57598910 T C 4.1161e-05 0.761966 136.157 1.8E-31 1.87025 26.9 TUBB1 missense won 20:57832175:A:C 0.00127188897822 610.53 0.00028364959561 0.0872056 126.618491947 20:57832175:A:C 610.53 0.00028364959561 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598918:G:A 20 57598918 A G 5.45658e-05 0.907681 246.741 1.3E-55 2.08634 26.5 TUBB1 missense won 20:57832099:G:A 0.00355677019817 1026.51 0.00085493666449 0.130392 218.187994036 20:57832099:G:A 1026.51 0.00085493666449 TUBB1 0.0004 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57598966:C:T 20 57598966 T C 6.67067e-05 0.892216 227.041 2.6E-51 1.77852 28.5 TUBB1 missense won rs3761260 0.00422606084095 3307.49 0.00029009583684 -0.152418 198.48145386 rs3761260 3307.49 0.00029009583684 TUBB1 0.0012 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599032:A:G 20 57599032 G A 2.49732e-05 0.755746 131.017 2.5E-30 2.43736 25.6 TUBB1 missense won rs201909522 0.00011344407282 141.959 0.00010469996329 -0.0947618 128.240935624 rs201909522 141.959 0.00010469996329 TUBB1 0.0111 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599106:T:A 20 57599106 A T 2.19523e-05 0.928852 100.592 1.1E-23 2.01619 35 TUBB1 stop_gained won rs11570256 0.0198153276905 546.12 0.00364986347881 -0.311536 74.2652100347 rs6026778 1580.52 0.00036841731364 TUBB1 0.0016 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599203:C:T 20 57599203 T C 0.000242849 0.925563 1171.43 9.9E-257 2.0929 33 TUBB1 missense won rs235202 0.000426688635564 1256.05 0.00039794265225 0.068342 1123.53468193 rs759902315 1324.86 0.00036682208676 TUBB1 0.0008 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599342:C:T 20 57599342 T C 0.000283213 0.915176 366.543 1.1E-81 1.06318 24.5 TUBB1 missense lost 20:57556330:G:GGGAGGGCATGGC 0.696707838385 406.913 0.627587177616 0.864329 10.0166336416 20:57597970:A:C 13951.3 0.00516097123201 TUBB1 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599434:C:T 20 57599434 T C 1.40521e-05 0.538296 31.6436 1.9E-08 1.74408 32 TUBB1 missense lost rs554731582 0.0292716683901 1038.56 0.00089187044164 -0.491005 21.7420760586 rs141490673 4279.56 0.00015987832249 TUBB1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599485:AC:A 20 57599485 A AC 1.4651e-05 0.922753 68.6577 1.2E-16 2.11105 25.6 TUBB1 frameshift won rs113675886 0.00353960436563 395.922 0.00061381053504 -0.124517 60.7311998332 rs76066771 397.353 0.00058635169609 N/A N/A N/A N/A N/A blood_PLATELET_DISTRIB_WIDTH_v2 20:57599701:G:A 20 57599701 A G 2.09394e-05 0.77555 56.7656 4.9E-14 1.78491 27.6 TUBB1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TUBB1 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57599761:G:A 20 57599761 A G 4.67493e-05 0.90194 82.0318 1.3E-19 1.22396 23.7 TUBB1 missense lost rs571971615 0.227162438077 542.798 0.034330531225 -0.596969 22.4710711736 20:57597970:A:C 13951.3 0.00093581539921 TUBB1 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57613605:C:G 20 57613605 G C 0.000860375 0.969819 274.178 1.4E-61 0.537394 24.9 SLMO2 missense lost rs186658310 0.899819864608 284.22 0.8680276224 -0.535991 0.724695605322 20:57597970:A:C 13951.3 0.016556483584 PRELID3B 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57766673:C:T 20 57766673 T C 0.0056338 0.943243 48.931 2.7E-12 -0.085518 25.6 ZNF831 missense lost rs191157364 0.760624058001 55.6073 0.669302335881 0.0933647 0.799962342714 20:57597970:A:C 13951.3 0.00015549341809 ZNF831 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:57829790:G:C 20 57829790 C G 0.000208091 0.84075 40.833 1.7E-10 0.430937 25.9 ZNF831 missense lost 20:57594684:C:T 1.03168982709 13720.8 0.00307030134609 0.509982 0.0100922974813 20:57597970:A:C 13951.3 0.00304904961124 ZNF831 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 20:58318188:C:A 20 58318188 A C 0.000115821 0.797925 53.3234 2.8E-13 0.680245 24.2 PHACTR3 missense lost 20:57598808:G:A 1.01448237598 3334.27 0.016224135876 1.46873 0.00277593704664 rs773385727 4304.42 0.00015544354329 PHACTR3 0.0000 0.0099 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 22:21235389:A:G 22 21235389 G A 0.00500356 0.993589 67.5049 2.1E-16 -0.114061 25.3 SNAP29 missense lost rs193171306 1.00000213687 67.8863 0.994383907344 0.113911 7.70602889597e-11 rs147739461 70.5091 0.992637601344 SNAP29 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 22:29091856:AG:A 22 29091856 A AG 0.00250696 0.876417 38.4576 5.6E-10 0.125902 35 CHEK2 frameshift won 22:29692497:T:G 0.00646905551036 143.451 0.00173428103809 0.0318384 32.5200610509 22:29692497:T:G 143.451 0.00173428103809 N/A N/A N/A N/A N/A blood_PLATELET_DISTRIB_WIDTH_v2 22:43275082:C:T 22 43275082 T C 0.00585122 0.930133 31.7636 1.7E-08 -0.0611933 25.3 PACSIN2 missense lost rs2010366 0.573526305185 2578.36 0.00706544475844 -0.0937139 1.87074626611 rs777106511 2643.21 0.00648952691776 PACSIN2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 2:68615546:A:C 2 68615546 C A 0.00870589 0.982982 154.482 1.8E-35 0.121861 21.6 PLEK missense won N/A N/A N/A N/A N/A N/A rs141250842 145.185 0.783798584976 PLEK 0.0013 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 2:69420480:C:T 2 69420480 T C 5.54465e-05 0.953607 31.5049 2.0E-08 -0.704146 31 ANTXR1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ANTXR1 0.0000 0.0017 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 3:128780764:A:G 3 128780764 G A 0.00082493 0.9345 248.099 6.7E-56 0.534629 23.2 GP9 missense won N/A N/A N/A N/A N/A N/A rs557662044 138.445 0.525404623104 GP9 0.2665 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 5:75960968:G:C 5 75960968 C G 0.00590245 0.930086 46.246 1.0E-11 0.0890049 27.7 IQGAP2 missense won rs250722 0.0208128323296 47.6562 0.020196957456 0.0145944 33.8650101424 rs10045408 134.838 0.00010244476225 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 6:31605016:T:C 6 31605016 C T 0.00828453 0.99288 32.0304 1.5E-08 -0.0558494 29.9 PRRC2A missense lost rs572095451 0.999567193144 34.106 0.938736205456 0.0598441 1.5003225342e-06 rs2596528 204.403 0.00719411008761 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 6:31964621:G:GCT 6 31964621 GCT G 0.00485394 0.569777 66.6398 3.3E-16 0.142152 34 C4A frameshift lost rs142674470 0.219476811462 98.1345 0.149039235136 -0.07754 18.8263942486 rs2596528 204.403 0.00114969821184 N/A N/A N/A N/A N/A blood_PLATELET_DISTRIB_WIDTH_v2 6:32052216:C:T 6 32052216 T C 0.00923232 0.996056 33.3351 7.8E-09 0.0655986 21.5 TNXB missense lost rs16870014 0.999888908457 43.1937 0.771672645601 -0.0744789 1.02855588912e-07 6:31830593:A:C 130.57 0.259273437721 TNXB 0.0001 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 6:32151458:G:A 6 32151458 A G 0.00535425 0.979931 31.2432 2.3E-08 -0.0690724 26.1 AGER missense lost rs145447055 0.998791919816 34.46 0.905555882449 0.0702187 1.14064234249e-05 rs2596528 204.403 0.00423233518096 AGER 0.0865 0.0000 0.0047 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 6:32168996:C:G 6 32168996 G C 0.00897595 0.99637 33.9636 5.6E-09 0.0642202 24.2 NOTCH4 missense lost rs116296029 0.997432937518 40.4227 0.838054195209 -0.0717628 5.60253493215e-05 6:31830593:A:C 130.57 0.2457383184 NOTCH4 0.0037 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 6:32802938:C:T 6 32802938 T C 0.00565692 0.989658 36.7611 1.3E-09 0.0754001 23.5 TAP2 missense lost rs145591506 0.870186950333 43.5709 0.734183354025 -0.0739689 0.165818980693 6:31830593:A:C 130.57 0.1410828721 XXbac-BPG246D15.9 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 7:100027688:C:G 7 100027688 G C 0.00772002 0.949572 31.3947 2.1E-08 -0.061696 24.7 MEPCE missense lost rs374789575 1.00132964759 847.384 0.037098226881 0.0738595 1.38669472959e-05 7:100077273:A:G 968.434 0.0301994884 MEPCE 0.0000 0.0000 0.0002 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 8:19811733:G:A 8 19811733 A G 0.000436029 0.837003 33.1391 8.6E-09 0.25375 23.3 LPL missense lost rs34266755 0.00295751289428 40.2705 0.00243377448889 -0.0158009 29.6327006211 rs2410620 290.19 0.00011649748356 LPL 0.0000 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 9:304670:C:T 9 304670 T C 0.000793809 0.81183 53.4846 2.6E-13 0.261439 23.3 DOCK8 missense won rs12551953 0.0077706332247 455.342 0.00091274077456 -0.0405511 44.4707463744 9:273178:G:GA 592.991 0.00023174277361 DOCK8 0.0000 0.0000 0.0000 0.1109 blood_PLATELET_DISTRIB_WIDTH_v2 9:420579:A:G 9 420579 G A 0.00459921 0.949284 247.084 1.1E-55 0.20929 32 DOCK8 missense won rs7024777 0.00534167876956 434.889 0.00303489708201 -0.0387939 212.286690864 9:273178:G:GA 592.991 0.000816187761 DOCK8 0.0000 0.0000 0.0018 0.0069 blood_PLATELET_DISTRIB_WIDTH_v2 9:113148268:T:C 9 113148268 C T 0.00484582 0.939119 46.6494 8.5E-12 0.0910151 22.8 SVEP1 missense lost 9:113312231:G:C 0.267229701292 212.154 0.058759699216 0.0804142 10.8853765028 9:113312231:G:C 212.154 0.058759699216 SVEP1 0.0021 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 9:113312230:C:G 9 113312230 G C 0.00145128 0.959152 42.6335 6.6E-11 0.16346 28.2 SVEP1 missense won rs11789093 0.00039303102128 54.6588 0.00030656157921 0.0138387 40.9598371608 9:112797542_CAT_C 56.2617 0.00010544414596 SVEP1 0.0002 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 9:135863638:C:T 9 135863638 T C 0.00281044 0.901684 52.5851 4.1E-13 0.12916 22.5 GFI1B missense won rs111425801 0.0581224875277 106.973 0.028571478961 -0.0511603 30.2864078457 9:136138765_GCGCCCACCACTA_G 128.632 0.00011309897104 GFI1B 0.0039 0.0000 0.0000 0.0000 blood_PLATELET_DISTRIB_WIDTH_v2 9:135864488:G:A 9 135864488 A G 7.55845e-05 0.837678 37.8987 7.5E-10 0.737323 26.7 GFI1B missense won rs873202 0.00038757801901 46.1451 0.00031831555396 0.0164985 36.421165193 9:136004770:C:T 50.1738 0.00016264155961 GFI1B 0.0262 0.0006 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_RBC_DISTRIB_WIDTH_v2 10:45953858:C:CA 10 45953858 CA C 0.000107703 0.731113 45.6868 1.4E-11 0.69623 35 MARCH8 frameshift won rs527558179 0.0150877142717 60.4519 0.011402609089 -0.120642 35.1525021242 10:45965312_CAAAAAAAAAA_C 230.145 0.00012100220001 N/A N/A N/A N/A N/A blood_RBC_DISTRIB_WIDTH_v2 10:45959729:A:G 10 45959729 G A 0.00262037 0.941163 61.0026 5.7E-15 -0.151871 22.4 MARCH8 missense won 10:45965312_CAAAAAAAAAA_C 0.00808458221948 230.145 0.00214291223056 -0.0305815 50.5257677873 10:46047757_TA_T 274.644 0.000736253956 MARCH8 0.0221 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 10:46246238:G:A 10 46246238 A G 0.0088517 0.935932 41.2399 1.3E-10 0.0689732 23.7 FAM21C missense lost rs17157883 0.857214101078 59.8459 0.590707530625 -0.0631209 0.22669370488 10:46047757_TA_T 274.644 0.030345291601 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 10:96447562:T:A 10 96447562 A T 0.00322895 0.987065 42.5121 7.0E-11 0.107697 35 CYP2C18 stop_gained lost rs111527282 1.00004859431 42.6192 0.997535520289 -0.107262 2.50964857585e-08 rs10786170 169.795 0.00397705548321 CYP2C18 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 10:96535173:T:C 10 96535173 C T 0.00301797 0.998864 40.9189 1.6E-10 0.10982 24.3 CYP2C19 missense lost rs551713481 1.00017396611 41.0805 0.996239541924 -0.109522 3.09567605868e-07 rs10786170 169.795 0.00388853263561 RP11-400G3.5 0.0068 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 11:5248004:G:A 11 5248004 A G 1.68678e-05 0.609495 53.9638 2.0E-13 2.10799 42 HBB stop_gained won N/A N/A N/A N/A N/A N/A rs185233978 39.4826 0.00259323340644 HBB 0.0001 0.0033 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 11:116701353:C:T 11 116701353 T C 0.000180254 0.815693 32.0561 1.5E-08 0.470531 35 APOC3 stop_gained won N/A N/A N/A N/A N/A N/A rs1145210 30.7753 0.00021787236025 APOC3 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 11:116701354:G:A 11 116701354 A G 0.00224197 0.92045 215.567 8.4E-49 0.316323 31 APOC3 splice_donor won 11:116623213_TA_T 0.000281629504579 226.472 0.00026806857984 -0.0411527 208.39249656 11:116623213_TA_T 226.472 0.00026806857984 APOC3 0.0001 0.0000 0.1104 0.8914 blood_RBC_DISTRIB_WIDTH_v2 13:73319139:G:A 13 73319139 A G 0.0040518 0.9402 45.7641 1.3E-11 0.111703 28.6 BORA missense won N/A N/A N/A N/A N/A N/A rs144254157 44.4957 0.902475300169 BORA 0.0472 0.1196 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 14:74205345:C:T 14 74205345 T C 0.00419368 0.970387 33.4778 7.2E-09 -0.0907383 25.5 ELMSAN1 missense lost rs191433274 0.859803038033 106.448 0.270407280049 0.10079 0.177155835035 rs7148979 631.963 0.021898968289 ELMSAN1 0.0000 0.0000 0.0005 0.0000 blood_RBC_DISTRIB_WIDTH_v2 15:78911017:T:C 15 78911017 C T 0.00146722 0.747009 32.2802 1.3E-08 -0.163935 LOW NONE N/A lost rs117592333 0.0902950984434 140.167 0.020794793616 0.0564975 15.7950970333 rs71148512 632.004 0.00061912885329 CHRNA3 0.7582 0.0714 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 16:88782050:G:A 16 88782050 A G 0.00993701 0.908822 30.6188 3.1E-08 0.0588796 24.7 PIEZO1 missense lost rs527468645 0.863262116719 42.8958 0.616192030441 -0.0708238 0.153832406607 rs837756 75.4342 0.00400852330641 PIEZO1 0.0001 0.0000 0.0001 0.0000 blood_RBC_DISTRIB_WIDTH_v2 16:88788037:G:A 16 88788037 A G 0.000963242 0.953717 51.552 7.0E-13 0.225579 31 PIEZO1 missense won rs837756 0.000767397332391 75.4342 0.00052444206049 -0.0171145 48.7353803198 rs837756 75.4342 0.00052444206049 PIEZO1 0.0170 0.0000 0.0118 0.0000 blood_RBC_DISTRIB_WIDTH_v2 17:58037438:A:C 17 58037438 C A 0.00334584 0.906573 39.5902 3.1E-10 0.111612 27.6 RNFT1 missense lost rs149532844 0.0711396358979 53.4231 0.052719374449 -0.0321701 21.2876246218 rs201184664 177.926 0.011502777001 RP11-178C3.1 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 19:12995811:A:C 19 12995811 C A 3.83436e-05 0.625535 40.8302 1.7E-10 1.33251 34 KLF1 missense won N/A N/A N/A N/A N/A N/A rs73013069 30.6065 0.000129846025 KLF1 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 19:12995833:T:TC 19 12995833 TC T 0.000204627 0.842305 444.267 1.3E-98 1.5113 35 KLF1 frameshift lost 19:12995834:C:CC 0.919635289056 469.424 0.870350921476 1.5022 0.747681309558 19:12995834:C:CC 469.424 0.870350921476 N/A N/A N/A N/A N/A blood_RBC_DISTRIB_WIDTH_v2 19:12996474:AG:A 19 12996474 A AG 1.34596e-05 0.902814 38.5697 5.3E-10 1.58269 31 KLF1 frameshift won rs77440950 0.000320218326877 118.023 0.00010464676209 -0.0298311 37.2016685308 rs62109862 119.01 0.00010349603289 N/A N/A N/A N/A N/A blood_RBC_DISTRIB_WIDTH_v2 19:35775865:C:G 19 35775865 G C 0.000497329 0.868685 32.4773 1.2E-08 -0.256395 24.0 HAMP missense won rs10421599 0.00036027354527 83.9473 0.000139381636 -0.020233 31.2561056894 rs10421599 83.9473 0.000139381636 HAMP 0.0046 0.0049 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 1:43308263:G:A 1 43308263 A G 0.0042045 0.979905 62.4524 2.7E-15 -0.112288 24.9 ERMAP missense lost rs201520271 0.857958492269 63.5501 0.843138987076 0.13428 0.339585897954 rs710218 238.752 0.00074652447076 ERMAP 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 1:156280971:G:A 1 156280971 A G 0.00143434 0.907647 35.1259 3.1E-09 -0.167695 24.0 CCT3 missense lost 1:156280969:G:A 1.0 35.1259 1.0 -0.167695 0.0 rs12724449 73.6827 0.00021971836441 CCT3 0.0060 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 1:158614141:G:A 1 158614141 A G 0.000606254 0.871042 37.1167 1.1E-09 0.222826 29.5 SPTA1 missense lost rs113786326 0.0235231086931 46.5447 0.018758315521 -0.0437335 26.6044416723 rs2022003 506.699 0.00129065592049 SPTA1 0.0006 0.0009 0.0001 0.0000 blood_RBC_DISTRIB_WIDTH_v2 20:18491700:G:A 20 18491700 A G 0.000175126 0.669817 59.3595 1.3E-14 0.679564 34 SEC23B missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A SEC23B 0.0000 0.0000 0.2484 0.6770 blood_RBC_DISTRIB_WIDTH_v2 20:18507015:A:G 20 18507015 G A 9.93761e-05 0.924724 32.1367 1.4E-08 0.578876 33 SEC23B splice_acceptor won N/A N/A N/A N/A N/A N/A N/A N/A N/A SEC23B 0.5436 0.9867 0.2963 0.0000 blood_RBC_DISTRIB_WIDTH_v2 22:29138301:A:G 22 29138301 G A 0.0024844 0.985697 50.361 1.3E-12 0.128983 27.6 HSCB missense lost rs529178827 0.997706063373 51.3011 0.979422956964 -0.135582 6.63278219917e-05 rs5762768 176.925 0.00324003439369 HSCB 0.0000 0.0000 0.0001 0.0023 blood_RBC_DISTRIB_WIDTH_v2 22:37466566:T:A 22 37466566 A T 2.71502e-05 0.975381 30.1943 3.9E-08 1.05412 27.9 TMPRSS6 missense lost 22:37480291:G:C 0.00596713874344 34.9645 0.00515304315409 0.0791247 25.7096198618 rs34374682 527.167 0.00017302508521 TMPRSS6 0.0000 0.0000 0.0000 0.0116 blood_RBC_DISTRIB_WIDTH_v2 22:37469593:C:T 22 37469593 T C 0.000229275 0.930634 86.8561 1.2E-20 0.600671 24.6 TMPRSS6 missense lost rs143562710 1.19556103702 121.275 0.856250414244 -0.790558 0.757972479624 rs877908 2108.26 0.00014625032356 TMPRSS6 0.0000 0.0000 0.0073 0.0820 blood_RBC_DISTRIB_WIDTH_v2 2:68615546:A:C 2 68615546 C A 0.00873484 0.982982 37.5378 9.0E-10 -0.0678343 21.6 PLEK missense lost 2:68873071:A:G 0.174375772268 40.2853 0.162483160464 -0.0278203 12.7331696778 2:70091722_CTT_C 47.3837 0.000122080401 PLEK 0.0013 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 2:219892500:G:A 2 219892500 A G 0.00242382 0.814238 35.7688 2.2E-09 -0.126542 24.4 CCDC108 missense lost 2:220081416:G:A 0.293632554957 97.1558 0.108103521681 -0.0787419 7.50698049912 rs6736362 197.24 0.00129159734544 CCDC108 0.0329 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 3:48613055:T:A 3 48613055 A T 4.73996e-05 0.570608 32.6209 1.1E-08 -1.13311 LOW NONE N/A lost 3:49713546:A:C 0.377798723156 37.0381 0.332742078244 -0.90701 4.84394436747 3:49713546:A:C 37.0381 0.332742078244 COL7A1 0.0010 0.0000 0.6646 0.0028 blood_RBC_DISTRIB_WIDTH_v2 3:49713546:A:C 3 49713546 C A 6.6898e-05 0.66279 37.0381 1.2E-09 -0.90701 27.1 APEH missense won rs73078824 0.00032193518741 63.7854 0.00018693725625 0.0183071 35.720907766 rs73078824 63.7854 0.00018693725625 APEH 0.0036 0.0000 0.0003 0.0000 blood_RBC_DISTRIB_WIDTH_v2 3:127396573:C:T 3 127396573 T C 0.00691032 0.957507 42.6677 6.5E-11 -0.080594 36 ABTB1 stop_gained lost rs189322878 0.992898455025 44.2759 0.956834156041 0.0804606 0.000539872404469 rs56011843 59.6457 0.00012764028484 ABTB1 0.0021 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 3:133476769:C:T 3 133476769 T C 0.00119517 0.942472 57.0465 4.3E-14 -0.219956 24.1 TF missense won N/A N/A N/A N/A N/A N/A rs13326361 33.3009 0.00422015239129 TF 0.0000 0.0000 0.0010 0.0004 blood_RBC_DISTRIB_WIDTH_v2 3:171338223:T:G 3 171338223 G T 0.000387075 0.887234 36.2938 1.7E-09 0.302865 26.1 PLD1 missense won 3:171287151_TCCC_T 0.000527211088138 54.9745 0.00034806126096 -0.0175255 34.6462449717 3:171416601_CA_C 115.346 0.00015160750641 PLD1 0.0635 0.0000 0.0000 0.0145 blood_RBC_DISTRIB_WIDTH_v2 3:171417570:G:A 3 171417570 A G 0.00458147 0.934652 188.109 8.2E-43 0.20462 26.9 PLD1 missense won 3:171394331_CT_C 0.00111499913981 195.057 0.00107528247225 0.0318885 175.756219338 rs16856859 261.585 0.00038194057489 PLD1 0.0000 0.0000 0.0003 0.2757 blood_RBC_DISTRIB_WIDTH_v2 3:171442535:C:A 3 171442535 A C 0.00280552 0.909048 251.856 1.0E-56 0.311021 25.9 PLD1 missense won rs4894769 0.00348439182386 434.332 0.00202049351001 0.0400064 223.000081679 rs4894769 434.332 0.00202049351001 PLD1 0.0443 0.0000 0.0223 0.0000 blood_RBC_DISTRIB_WIDTH_v2 5:1073873:C:T 5 1073873 T C 0.000248947 0.902577 30.6071 3.2E-08 -0.334352 23.1 SLC12A7 missense lost rs528681155 1.15977559234 37.0371 0.958427294049 0.366868 0.181133945547 rs56738155 112.271 0.00010151368516 SLC12A7 0.0104 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 5:1212453:G:A 5 1212453 A G 0.00445647 0.972121 87.3568 9.1E-21 -0.138311 22.5 SLC6A19 missense lost rs117656550 1.00046546589 405.572 0.215491852521 0.174648 4.73054730553e-06 rs56287436 720.358 0.00377685222721 SLC6A19 0.0054 0.0035 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 5:10264788:A:G 5 10264788 G A 0.000523089 0.864549 37.7207 8.2E-10 -0.270737 22.2 CCT5 missense won N/A N/A N/A N/A N/A N/A 5:10250441:G:A 32.8843 0.739854581904 CCT5 0.0008 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 6:16286061:C:A 6 16286061 A C 0.00146287 0.923729 61.3374 4.8E-15 -0.19439 32 GMPR missense won 6:16281187:C:T 0.000446180846055 62.1734 0.00044018138025 0.0168261 58.7735085942 6:16281187:C:T 62.1734 0.00044018138025 GMPR 0.0661 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 6:16290848:T:TAC 6 16290848 TAC T 0.0018632 0.936787 102.017 5.5E-24 -0.231037 35 GMPR frameshift won N/A N/A N/A N/A N/A N/A rs9383146 73.5958 0.00088535407401 N/A N/A N/A N/A N/A blood_RBC_DISTRIB_WIDTH_v2 6:30043301:G:C 6 30043301 C G 0.000797173 0.995511 32.1353 1.4E-08 -0.178415 26.5 RNF39 missense lost rs116533594 0.980567279545 32.4534 0.970956007641 0.232576 0.00306365898373 rs34302671 225.861 0.00525725054761 RNF39 0.0000 0.0000 0.0004 0.0000 blood_RBC_DISTRIB_WIDTH_v2 6:30124811:C:T 6 30124811 T C 0.00868384 0.934131 59.1913 1.4E-14 0.080611 22.4 TRIM10 missense won rs2097772 0.013756722901 113.005 0.00720568392769 0.0347522 46.1205947885 6:27141207_CTTTTTTTTTTTTTTTTT_C 544.021 0.00040580893809 TRIM10 0.0001 0.0266 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 6:109763498:C:G 6 109763498 G C 0.0027902 0.835081 30.5918 3.2E-08 0.112186 24.0 SMPD2 missense lost rs9487032 0.0492067428177 747.733 0.00201318229225 0.0513985 18.5250139197 rs6568570 850.669 0.00169737408064 SMPD2 0.0001 0.0000 0.3293 0.0000 blood_RBC_DISTRIB_WIDTH_v2 6:109763831:G:C 6 109763831 C G 0.00317183 0.937985 30.5546 3.2E-08 0.0931072 23.5 SMPD2 missense lost 6:109643672_CT_C 0.0199008845515 157.386 0.00386351751184 0.030421 22.5419584758 rs146055259 613.805 0.00043707337969 SMPD2 0.0000 0.0000 0.0323 0.0000 blood_RBC_DISTRIB_WIDTH_v2 7:100064620:G:A 7 100064620 A G 0.00696665 0.785537 153.669 2.7E-35 0.151441 24.7 TSC22D4 missense won 7:100197866:G:A 0.0323514423969 173.993 0.028572493156 0.0365447 103.36104378 7:100240296:G:A 660.112 0.00719750321161 TSC22D4 0.0000 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 7:100224387:C:T 7 100224387 T C 0.000966788 0.853484 60.2886 8.2E-15 -0.256064 30 TFR2 missense won 7:99702947:G:A 0.00898613907706 106.029 0.00510956195344 -0.0306461 49.4002161458 rs6465775 324.502 0.00017480541796 TFR2 0.0010 0.0000 0.0000 0.0000 blood_RBC_DISTRIB_WIDTH_v2 7:100225847:C:T 7 100225847 T C 0.00514385 0.994125 124.082 8.1E-29 -0.15023 21.6 NONE N/A won rs9801017 0.0166622558611 659.607 0.00313442099881 0.0498379 94.1158910544 7:100240296:G:A 660.112 0.00313166709769 TFR2 0.0014 0.0000 0.5241 0.4540 blood_RBC_DISTRIB_WIDTH_v2 8:98656894:G:A 8 98656894 A G 0.0064702 0.97622 53.312 2.8E-13 -0.0838794 24.0 MTDH missense lost rs540260547 1.0007823688 55.6182 0.959285083761 0.0892029 8.15489162997e-06 rs2449511 324.824 0.087380542404 MTDH 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_RED_COUNT_v2 10:46246238:G:A 10 46246238 A G 0.00885069 0.935932 36.2641 1.7E-09 -0.0636493 23.7 FAM21C missense lost rs12765244 0.820688742747 221.486 0.134372098624 0.0588912 0.320983907459 rs901683 243.803 0.080197708864 FAM21C 0.0000 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 11:5248004:G:A 11 5248004 A G 1.67631e-05 0.609495 63.4741 1.6E-15 2.27991 42 HBB stop_gained won N/A N/A N/A N/A N/A N/A 11:4920230_C_A 61.8327 0.001851150625 HBB 0.0001 0.0033 0.0000 0.0000 blood_RED_COUNT_v2 11:19246240:G:A 11 19246240 A G 0.000192197 0.737794 46.6207 8.6E-12 -0.522365 39 E2F8 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A E2F8 0.0000 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 11:67198887:C:T 11 67198887 T C 0.00406356 0.653001 31.7 1.8E-08 0.101105 25.7 RPS6KB2 missense lost rs186378239 0.381968097033 33.4354 0.362142779089 -0.103261 4.62492680604 11:66897377_CAA_C 122.061 0.027962862841 RPS6KB2 0.0001 0.0015 0.0000 0.0000 blood_RED_COUNT_v2 12:111885295:G:A 12 111885295 A G 0.000493132 0.861631 35.9451 2.0E-09 0.283834 32 SH2B3 missense won 12:110738448_CT_C 0.00229582410816 59.5979 0.00138467340544 -0.0242543 32.5830220361 rs56750693 258.426 0.00017217113796 SH2B3 0.0001 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00200647 0.885884 87.5867 8.1E-21 0.210938 32 SH2B3 missense lost rs551014092 1.018368555 93.9956 0.948933153424 -0.209045 0.00732093709258 rs565349424 314.071 0.00101918008516 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_RED_COUNT_v2 13:73319139:G:A 13 73319139 A G 0.00404031 0.9402 52.4341 4.4E-13 0.109566 28.6 BORA missense lost rs191078878 0.927840235428 52.9996 0.917940280464 -0.114045 0.070836189747 rs191078878 52.9996 0.917940280464 BORA 0.0472 0.1196 0.0000 0.0000 blood_RED_COUNT_v2 16:169168:C:T 16 169168 T C 0.000224279 0.697212 46.8382 7.7E-12 0.508218 27.1 NPRL3 missense lost 16:216593:T:C 0.0539958259982 177.058 0.014283835225 0.157202 27.5996803954 16:216593:T:C 177.058 0.014283835225 NPRL3 0.0000 0.0000 0.0000 0.0163 blood_RED_COUNT_v2 16:2086421:C:T 16 2086421 T C 0.00678843 0.956889 74.5767 5.8E-18 -0.100237 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A 16:2158570:G:A 49.4382 0.347055304996 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 16:67166731:G:A 16 67166731 A G 0.00680543 0.967352 52.5267 4.2E-13 0.0799928 22.8 C16orf70 missense lost rs191091369 1.00611160007 54.0634 0.977513848249 -0.080482 0.000488996661777 rs7187289 154.557 0.026228126401 C16orf70 0.0001 0.0480 0.0000 0.0000 blood_RED_COUNT_v2 16:88782050:G:A 16 88782050 A G 0.00995368 0.908822 52.6683 3.9E-13 0.0690033 24.7 PIEZO1 missense won rs4782405 0.0256179066127 93.472 0.014434821025 0.0191286 37.1578021784 rs74035509 121.005 0.003101041969 PIEZO1 0.0001 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 16:88782205:G:C 16 88782205 C G 0.00144337 0.954236 65.2645 6.5E-16 0.199279 23.3 PIEZO1 missense lost 16:88781091:G:C 1.00385814647 65.5163 1.0 0.194671 0.000242402932079 16:88853729:T:C 388.674 0.00151402701025 PIEZO1 0.0331 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 16:88798919:G:T 16 88798919 T G 0.0014321 0.936239 65.6873 5.3E-16 0.203006 22.4 PIEZO1 missense won rs551118 0.0100077498517 378.686 0.00173595555904 0.0377554 53.2021323844 16:88853729:T:C 388.674 0.00156662389636 PIEZO1 0.0076 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 17:16852187:A:G 17 16852187 G A 0.00697128 0.947032 75.2972 4.0E-18 0.102096 26.1 TNFRSF13B missense won N/A N/A N/A N/A N/A N/A rs28507905 60.8046 0.00070105271076 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 19:1047507:AGGAGCAG:A 19 1047507 A AGGAGCAG 0.00273391 0.908029 32.0748 1.5E-08 -0.104614 34 ABCA7 frameshift lost rs757293 0.0136285330629 54.1578 0.00807145918569 -0.0266641 25.0230242415 rs10425079 64.5409 0.000550418521 N/A N/A N/A N/A N/A blood_RED_COUNT_v2 19:12995833:T:TC 19 12995833 TC T 0.000209709 0.842305 44.5699 2.5E-11 0.484508 35 KLF1 frameshift lost 19:12995834:C:CC 1.04369423159 53.1642 0.874975030801 0.51866 0.0208206170058 rs2974753 153.857 0.00018394140625 N/A N/A N/A N/A N/A blood_RED_COUNT_v2 19:41510282:A:G 19 41510282 G A 0.00573039 0.906639 34.0321 5.4E-09 -0.0740037 23.6 CYP2B6 missense lost rs184088518 0.957914208366 207.364 0.157210664004 0.0941819 0.0153952331677 rs184088518 207.364 0.157210664004 CYP2B6 0.0001 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 19:50017538:G:C 19 50017538 C G 0.00822583 0.955029 64.6559 8.9E-16 0.0831163 22.6 FCGRT missense won rs35279796 0.00147908271448 73.5884 0.00129954482064 0.0202746 59.7783490256 19:50016759:C:T 83.0371 0.00101951851401 FCGRT 0.0108 0.0000 0.0006 0.0000 blood_RED_COUNT_v2 1:118165603:G:A 1 118165603 A G 0.000573936 0.903197 48.4703 3.4E-12 0.291221 23.4 FAM46C missense won 1:120274455:G:A 0.000370931848901 55.6885 0.00032285261761 0.0155197 46.6212428621 rs11589332 64.1029 0.00027552016144 FAM46C 0.0003 0.0000 0.0005 0.0000 blood_RED_COUNT_v2 1:151804213:G:A 1 151804213 A G 0.00341545 0.949492 40.9841 1.5E-10 -0.107278 36 RORC stop_gained won rs939594 0.00168505643853 42.4642 0.00162632338729 0.0122037 37.6884118994 rs939594 42.4642 0.00162632338729 RORC 0.0001 0.0000 0.0000 0.0145 blood_RED_COUNT_v2 1:155206037:G:A 1 155206037 A G 0.00742727 0.877117 50.256 1.3E-12 -0.076117 21.8 GBA missense lost rs528163074 0.643662230958 98.1692 0.329511588961 0.0862277 1.96455590828 1:155178782:T:A 250.121 0.009707372676 GBA 0.0000 0.0000 0.0000 0.0021 blood_RED_COUNT_v2 1:155260382:C:T 1 155260382 T C 0.00241536 0.84936 41.1863 1.4E-10 -0.129387 24.3 PKLR missense lost rs572135153 0.908710587136 42.1395 0.8881554564 0.133598 0.0899646932415 1:155178782:T:A 250.121 0.00315373219561 PKLR 0.0004 0.0000 0.0775 0.0000 blood_RED_COUNT_v2 1:155261636:C:T 1 155261636 T C 0.00105792 0.864591 40.5063 2.0E-10 -0.198745 32 PKLR missense won 1:155178782:T:A 0.00797153607594 250.121 0.0012909649 -0.0299052 33.5961122699 1:155178782:T:A 250.121 0.0012909649 PKLR 0.0418 0.0000 0.0003 0.0000 blood_RED_COUNT_v2 1:155261649:C:T 1 155261649 T C 0.00634368 0.971679 36.8988 1.2E-09 0.0722715 20.8 PKLR missense lost 1:155191729_CTCTCT_C 0.989562584558 43.7579 0.834447537361 -0.077418 0.00101021443562 1:155178782:T:A 250.121 0.00414837758241 PKLR 0.0001 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 1:155261709:G:A 1 155261709 A G 0.0025629 0.899559 46.2164 1.1E-11 -0.132791 33 PKLR missense won 1:155136016_TAC_T 0.0041021473293 110.501 0.001715699241 -0.0194366 40.4858497676 1:155136016_TAC_T 110.501 0.001715699241 PKLR 0.0762 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 20:35696466:T:A 20 35696466 A T 0.000165152 0.736956 34.5307 4.2E-09 -0.466492 23.4 RBL1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A RBL1 0.0714 0.0000 0.0004 0.0000 blood_RED_COUNT_v2 3:49713546:A:C 3 49713546 C A 6.63964e-05 0.66279 39.2474 3.7E-10 -0.93008 27.1 APEH missense won rs59357103 0.000240028621559 39.6881 0.00023736332356 0.0155799 38.0407117787 rs759629469 47.2111 0.00012417313489 APEH 0.0036 0.0000 0.0003 0.0000 blood_RED_COUNT_v2 3:70014091:G:A 3 70014091 A G 0.00411688 0.961313 48.9984 2.6E-12 -0.100533 31 MITF missense lost rs190948281 0.942754967212 54.0054 0.855349372201 0.108187 0.0413336531305 3:69870063_CGT_C 169.011 0.002147766336 MITF 0.0001 0.0000 0.0001 0.0000 blood_RED_COUNT_v2 3:133476769:C:T 3 133476769 T C 0.00119025 0.942472 57.3281 3.7E-14 -0.21919 24.1 TF missense won rs11283697 0.00174640958901 60.0017 0.00166859178256 -0.0151569 52.6367282157 rs8177247 68.6625 0.00054641400025 TF 0.0000 0.0000 0.0010 0.0004 blood_RED_COUNT_v2 5:1212453:G:A 5 1212453 A G 0.00444233 0.972121 33.5022 7.1E-09 -0.0815179 22.5 SLC6A19 missense lost rs144352333 0.494640508084 36.6354 0.4523369536 0.0842939 2.94909254783 rs7705526 360.247 0.001107292176 SLC6A19 0.0054 0.0035 0.0000 0.0000 blood_RED_COUNT_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00186579 0.936787 49.43 2.1E-12 -0.160974 35 GMPR frameshift won rs7765828 0.00188760945105 88.8549 0.00105007754401 -0.0180901 45.2281709292 6:16282518_AG_A 98.2596 0.00057407680801 N/A N/A N/A N/A N/A blood_RED_COUNT_v2 6:135360757:C:G 6 135360757 G C 0.00258268 0.957096 37.8514 7.6E-10 -0.114665 22.0 HBS1L missense lost 6:135424723_CT_C 0.992057518634 6132.16 0.00612357896089 0.163118 0.000599327509765 6:135418635:C:T 6522.61 0.00654947066944 HBS1L 0.0000 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 6:135732649:T:C 6 135732649 C T 0.00509559 0.910051 33.781 6.2E-09 -0.0789876 21.9 AHI1 missense lost rs137966474 0.895514925428 162.833 0.185781688576 0.0789657 0.0973540638714 6:135418635:C:T 6522.61 0.00367602115204 AHI1 0.0028 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 7:2296552:A:G 7 2296552 G A 0.00375005 0.988495 37.7489 8.0E-10 0.0873144 24.4 SNX8 missense won rs10952012 0.00141892881832 42.7199 0.00125381852649 0.0162509 34.9585611691 rs10952012 42.7199 0.00125381852649 SNX8 0.0000 0.0000 0.0000 0.0001 blood_RED_COUNT_v2 7:100027688:C:G 7 100027688 G C 0.00772154 0.949572 30.8091 2.8E-08 0.0660631 24.7 MEPCE missense lost 7:100171627_GAC_G 1.00415893943 36.1359 0.856135676176 -0.0750708 0.000132948215975 7:100240296:G:A 1645.0 0.00738478985104 MEPCE 0.0000 0.0000 0.0002 0.0000 blood_RED_COUNT_v2 7:100064620:G:A 7 100064620 A G 0.0069789 0.785537 70.1667 5.4E-17 0.111706 24.7 TSC22D4 missense lost rs185470895 0.715637777688 70.343 0.713844181449 -0.119602 1.66507274161 7:100240296:G:A 1645.0 0.00720587067876 TSC22D4 0.0000 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 7:100174951:G:A 7 100174951 A G 0.000986114 0.867982 43.0449 5.3E-11 0.213624 32 LRCH4 missense lost rs536788737 0.944887003975 43.7179 0.930341269764 -0.251759 0.0336196034086 7:100240296:G:A 1645.0 0.00124991238681 LRCH4 0.0001 0.0000 0.0137 0.0000 blood_RED_COUNT_v2 7:100225847:C:T 7 100225847 T C 0.005153 0.994125 32.8752 9.8E-09 0.0718129 21.6 NONE N/A lost 7:100361580:TG:T 0.351407943566 1007.26 0.011469339025 0.0669346 5.45118539337 rs221788 1597.88 0.00280225185769 TFR2 0.0014 0.0000 0.5241 0.4540 blood_RED_COUNT_v2 7:100226902:C:T 7 100226902 T C 0.00378429 0.881336 98.9544 2.6E-23 0.158975 22.1 TFR2 missense won rs7807429 0.120911667391 791.44 0.015117686116 0.0701487 42.1015909401 7:100240296:G:A 1645.0 0.00516748197904 TFR2 0.0002 0.0000 0.0001 0.0478 blood_RED_COUNT_v2 7:100228655:G:T 7 100228655 T G 0.00603494 0.923732 44.1759 3.0E-11 0.0811308 23.2 TFR2 missense lost rs182858271 0.554481632346 102.063 0.239996131236 -0.0798673 2.88076183756 7:100240296:G:A 1645.0 0.00972324184225 TFR2 0.0000 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 7:100280070:C:T 7 100280070 T C 0.00174004 0.89928 45.4451 1.6E-11 0.160136 24.2 GIGYF1 missense lost 7:100230755:A:T 1.01939200381 47.2966 0.9794862961 0.161014 0.00423147542929 7:100240296:G:A 1645.0 0.00253698579225 GIGYF1 0.0228 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 7:100285473:C:T 7 100285473 T C 0.00513737 0.866001 48.4857 3.3E-12 0.0938803 23.5 GIGYF1 missense lost rs200070847 0.801221079992 245.378 0.158318043664 -0.0819639 0.533440137229 7:100240296:G:A 1645.0 0.00461853441604 GIGYF1 0.0003 0.0000 0.0003 0.0000 blood_RED_COUNT_v2 7:100319633:G:A 7 100319633 A G 0.00533913 0.826534 342.497 1.8E-76 -0.258092 23.9 EPO missense won rs2734887 0.0471215725954 439.133 0.036751957264 0.0647379 209.940897924 7:100240296:G:A 1645.0 0.00255403890625 EPO 0.0020 0.0000 0.0001 0.1020 blood_RED_COUNT_v2 9:5081828:G:C 9 5081828 C G 0.0010468 0.937121 58.6953 1.8E-14 0.216241 21.9 JAK2 missense won rs12005199 0.00498787072246 262.23 0.00111644193424 -0.0330114 50.6973699841 9:4778777:G:A 326.974 0.00014347487961 JAK2 0.0001 0.0000 0.0000 0.0001 blood_RED_COUNT_v2 9:32418353:C:T 9 32418353 T C 0.00128024 0.934964 58.8347 1.7E-14 0.202269 22.6 ACO1 missense won 9:32433526:T:C 0.0039108531058 89.0073 0.002585112336 0.0195282 51.7061244874 9:32428110_CA_C 104.778 0.000827310169 ACO1 0.1715 0.1105 0.0000 0.0000 blood_RED_COUNT_v2 9:32418473:A:G 9 32418473 G A 0.00146637 0.885165 38.8636 4.5E-10 -0.164831 26.2 ACO1 missense won rs1133071 0.00563269822173 90.917 0.002407766761 0.0195884 33.2489792197 9:32428110_CA_C 104.778 0.00154912300921 ACO1 0.0032 0.0000 0.0000 0.0000 blood_RED_COUNT_v2 9:114886569:C:T 9 114886569 T C 0.0031761 0.888348 44.6741 2.3E-11 0.113112 25.3 SUSD1 missense won rs7849537 0.00114248240317 65.2475 0.00078224258596 0.0183928 41.7051141686 rs61120558 73.147 0.00061164709225 SUSD1 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_RETICULOCYTE_COUNT_v2 10:24909638:T:C 10 24909638 C T 0.00297721 0.92294 33.7586 6.2E-09 -0.101808 23.5 ARHGAP21 missense lost rs61854305 0.2097280025 282.493 0.025063005969 0.0683875 9.91849958917 rs10828725 2151.29 0.002868352249 ARHGAP21 0.0000 0.0000 0.0031 0.0000 blood_RETICULOCYTE_COUNT_v2 11:10508903:G:T 11 10508903 T G 0.00893086 0.937752 106.231 6.6E-25 -0.106234 26.6 AMPD3 missense won rs10770059 0.00122850036878 158.244 0.00082470629329 -0.0263743 98.9147181821 11:9769562:C:G 161.753 0.00077001255081 AMPD3 0.0000 0.0000 0.0002 0.0000 blood_RETICULOCYTE_COUNT_v2 11:14865399:C:T 11 14865399 T C 0.00106971 0.906863 59.8099 1.0E-14 -0.241618 35 PDE3B stop_gained won rs81569 0.000141911136317 67.7468 0.00012528548761 0.0165448 58.3933993509 rs81569 67.7468 0.00012528548761 PDE3B 0.1111 0.0139 0.0003 0.0000 blood_RETICULOCYTE_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00201787 0.885884 80.2397 3.3E-19 0.203867 32 SH2B3 missense lost rs555346412 1.00301284676 94.4179 0.852396102009 -0.247062 0.000181815077996 rs28551113 885.907 0.00011749909609 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_RETICULOCYTE_COUNT_v2 12:112586091:G:C 12 112586091 C G 0.00149226 0.807902 33.2357 8.2E-09 -0.159227 24.2 TRAFD1 missense lost rs77415361 0.343896378812 812.725 0.014063350921 0.106214 5.6847272175 rs597808 1223.68 0.00106723742596 TRAFD1 0.0001 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 12:112673047:T:A 12 112673047 A T 0.00690866 0.996032 67.3779 2.2E-16 -0.0951528 20.7 HECTD4 missense lost rs113280084 1.00157051637 71.6572 0.941757675364 0.0986842 4.15146693729e-05 rs597808 1223.68 0.00668589134929 HECTD4 0.0173 0.0039 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 15:43499436:G:A 15 43499436 A G 0.00628869 0.975953 30.4838 3.4E-08 0.0674894 24.1 EPB42 missense won N/A N/A N/A N/A N/A N/A rs181075931 30.1988 0.910278187225 EPB42 0.0001 0.0000 0.0075 0.0002 blood_RETICULOCYTE_COUNT_v2 15:78567957:G:A 15 78567957 A G 0.000129828 0.790385 38.7857 4.7E-10 0.557536 22.6 DNAJA4 missense won rs11635166 0.00265357202821 210.117 0.000489825424 -0.0351991 34.8926980263 rs74410899 229.178 0.00010053671824 DNAJA4 0.0026 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 16:2086421:C:T 16 2086421 T C 0.00680829 0.956889 57.1529 4.0E-14 -0.0950681 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A 16:2158570:G:A 34.2375 0.347134250761 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88782050:G:A 16 88782050 A G 0.00994798 0.908822 112.411 2.9E-26 0.10871 24.7 PIEZO1 missense won rs12443806 0.0138728283799 137.424 0.011347788676 -0.0377722 87.4902552881 rs74035509 152.682 0.00308305894009 PIEZO1 0.0001 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88782159:C:T 16 88782159 T C 0.000218063 0.871875 30.531 3.3E-08 0.397797 25.7 PIEZO1 missense lost rs6500490 0.00164359659283 51.5115 0.00097416397456 -0.0186728 28.1056480979 16:88803124:T:C 75.6795 0.00048044694481 PIEZO1 0.0054 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88782205:G:C 16 88782205 C G 0.00143229 0.954236 185.278 3.4E-42 0.347865 23.3 PIEZO1 missense lost rs562212325 1.00609347904 189.381 0.984296141689 -0.343849 0.00171464547162 rs2968478 267.27 0.00164375917489 PIEZO1 0.0331 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88786073:G:A 16 88786073 A G 3.00334e-05 0.839812 49.5992 1.9E-12 1.28548 32 PIEZO1 missense won rs772054169 0.000614615584368 77.5148 0.00039327252721 -0.04904 47.1704130854 rs1558151 114.878 0.00010151570025 PIEZO1 0.0081 0.0000 0.0002 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88793220:G:A 16 88793220 A G 0.00132652 0.935719 29.9465 4.4E-08 0.147069 24.5 PIEZO1 missense lost rs72813548 0.0160789098764 73.7295 0.00653072480641 -0.0236698 22.8334164708 rs2968478 267.27 0.00163669602721 PIEZO1 0.0594 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88798288:C:G 16 88798288 G C 0.000191594 0.875973 73.9696 7.9E-18 0.622886 25.8 PIEZO1 missense won 16:89660343:G:A 0.000513851388617 76.9193 0.00049414622436 0.0254426 70.6540806379 rs77440982 79.5826 0.00015855342724 PIEZO1 0.0241 0.0000 0.0004 0.0000 blood_RETICULOCYTE_COUNT_v2 16:88798919:G:T 16 88798919 T G 0.00142037 0.936239 180.72 3.4E-41 0.347678 22.4 PIEZO1 missense lost 16:88781091:G:C 0.996068642325 184.314 0.976645968516 0.339287 0.000699658777236 rs2968478 267.27 0.00169949238001 PIEZO1 0.0076 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 17:33884124:C:T 17 33884124 T C 0.00194693 0.925583 64.9267 7.8E-16 0.170749 23.6 SLFN14 missense won rs551616134 0.0206768428446 92.4173 0.014526275625 -0.0469429 47.596981393 rs78427228 356.049 0.00021793731129 SLFN14 0.0334 0.0000 0.0002 0.0000 blood_RETICULOCYTE_COUNT_v2 17:42331919:C:T 17 42331919 T C 5.10092e-05 0.704317 37.6021 8.7E-10 0.92622 22.6 SLC4A1 missense won rs9747308 0.000469816883333 57.814 0.00030556788025 -0.0231981 35.9896955354 rs9747308 57.814 0.00030556788025 SLC4A1 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 17:74383107:CG:C 17 74383107 C CG 0.00361394 0.973727 257.228 6.9E-58 -0.262407 35 SPHK1 frameshift won rs56837304 0.00945030506095 341.659 0.00711493937001 -0.0388215 209.647236811 17:74434003:C:T 362.647 0.00286466871076 N/A N/A N/A N/A N/A blood_RETICULOCYTE_COUNT_v2 18:21057210:G:A 18 21057210 A G 0.00510936 0.967763 120.296 5.4E-28 0.146065 31 RIOK3 missense won N/A N/A N/A N/A N/A N/A rs183907952 80.2854 0.6858821124 RIOK3 0.0081 0.0000 0.0002 0.0379 blood_RETICULOCYTE_COUNT_v2 18:21057228:C:T 18 21057228 T C 0.00577446 0.910028 202.656 5.5E-46 0.180233 24.2 RIOK3 missense lost rs139563497 1.01599622251 215.722 0.954458657296 -0.185477 0.0128611992275 rs139563497 215.722 0.954458657296 RIOK3 0.0003 0.0000 0.0034 0.0231 blood_RETICULOCYTE_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00977787 0.967311 99.733 1.7E-23 -0.100609 26.0 S1PR2 missense won rs10409243 0.0140694771574 214.388 0.00654510124324 0.0296309 77.4765661055 rs34797640 867.169 0.00020660900121 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 19:17476153:T:G 19 17476153 G T 0.00371813 0.914963 58.3181 2.2E-14 -0.124112 21.9 PLVAP missense won rs112613803 0.0172937135734 114.44 0.00881279725225 0.0362569 43.9883271604 rs140594952 265.348 0.00104204359249 PLVAP 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 19:40964064:G:A 19 40964064 A G 0.00676389 0.872551 76.2043 2.6E-18 0.111137 32 BLVRB missense won N/A N/A N/A N/A N/A N/A rs556857937 53.9936 0.635075111056 BLVRB 0.0000 0.0000 0.0546 0.0985 blood_RETICULOCYTE_COUNT_v2 19:55697712:G:A 19 55697712 A G 0.00271203 0.871871 30.2443 3.8E-08 -0.0986203 41 PTPRH stop_gained lost rs4020012 0.000693465346123 102.908 0.00020380703121 -0.023842 28.6723829015 rs35266089 107.898 0.00019178926144 PTPRH 0.0533 0.0577 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:154956373:A:G 1 154956373 G A 0.000435744 0.910445 38.7292 4.9E-10 0.305768 23.2 FLAD1 missense lost rs559184111 0.923027651162 109.022 0.327898245376 -0.430757 0.0596851836158 1:155261709:G:A 264.674 0.087505922596 N/A N/A N/A N/A N/A blood_RETICULOCYTE_COUNT_v2 1:155260382:C:T 1 155260382 T C 0.0024189 0.84936 30.9456 2.7E-08 0.114061 24.3 PKLR missense lost rs575402937 1.00846611799 33.4001 0.934356157641 -0.115448 0.000552172743176 rs535494646 50.3734 0.001121446144 PKLR 0.0004 0.0000 0.0775 0.0000 blood_RETICULOCYTE_COUNT_v2 1:155261709:G:A 1 155261709 A G 0.0025588 0.899559 264.674 1.6E-59 0.307725 33 PKLR missense won N/A N/A N/A N/A N/A N/A rs180864404 240.136 0.754735250025 PKLR 0.0762 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:155264120:C:G 1 155264120 G C 3.29435e-05 0.811592 52.1403 5.2E-13 1.34508 27.1 PKLR missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PKLR 0.0003 0.0000 0.0024 0.0000 blood_RETICULOCYTE_COUNT_v2 1:155271095:G:A 1 155271095 A G 0.000213153 0.975162 49.5781 1.9E-12 -0.424452 26.9 PKLR missense won N/A N/A N/A N/A N/A N/A 1:155260780_AAAT_A 41.9023 0.00015647007744 PKLR 0.0000 0.0000 0.0001 0.0045 blood_RETICULOCYTE_COUNT_v2 1:158450451:G:A 1 158450451 A G 0.00841177 0.967157 30.5124 3.3E-08 -0.0546735 23.2 OR10R2 missense lost rs188676710 1.05920147398 34.9935 0.923565206529 0.0636352 0.0259718174445 rs2022003 2198.84 0.020835190336 OR10R2 0.0018 0.0000 0.0015 0.0000 blood_RETICULOCYTE_COUNT_v2 1:158583604:C:A 1 158583604 A C 0.000802328 0.972715 163.805 1.7E-37 0.438911 27.8 SPTA1 missense won rs145746722 0.00456714256166 749.01 0.000998812816 0.055049 142.413028144 rs2022003 2198.84 0.00028580607364 SPTA1 0.0001 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:158605757:C:T 1 158605757 T C 0.00195381 0.94596 38.4466 5.6E-10 -0.133983 27.8 SPTA1 missense lost rs555568708 0.623749771864 41.8379 0.573189810649 0.149338 1.69907677723 rs2022003 2198.84 0.00378948585744 SPTA1 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:158613207:C:A 1 158613207 A C 0.000408361 0.860242 59.3745 1.3E-14 0.38893 25.2 SPTA1 missense lost rs186270716 0.144567463226 160.73 0.053403974649 -0.165567 22.8073425184 rs2022003 2198.84 0.00018846622089 SPTA1 0.0017 0.0320 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:248020849:G:T 1 248020849 T G 0.00140484 0.85441 36.5964 1.5E-09 0.163212 35 TRIM58 stop_gained lost rs12096473 0.124416811407 596.417 0.00763426830049 -0.0900043 15.3324813615 rs12096473 596.417 0.00763426830049 TRIM58 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 1:248458435:A:G 1 248458435 G A 0.00682054 0.98122 38.0792 6.8E-10 0.0760453 21.4 OR2T12 missense lost rs139125253 1.00009629506 38.6209 0.9860688601 -0.0771744 8.8270375808e-08 1:248039294:G:A 1951.23 0.00778917448969 OR2T12 0.0346 0.0000 0.0027 0.0000 blood_RETICULOCYTE_COUNT_v2 20:33872191:A:G 20 33872191 G A 0.00033664 0.861504 44.0143 3.3E-11 -0.367639 26.6 EIF6 missense won 20:33422769_CA_C 0.000522221404336 86.2667 0.00026644359361 -0.0180765 42.0256411963 20:33422769_CA_C 86.2667 0.00026644359361 EIF6 0.0000 0.0000 0.0025 0.0033 blood_RETICULOCYTE_COUNT_v2 20:57598808:G:A 20 57598808 A G 0.00133894 0.96877 35.4209 2.7E-09 0.154863 24.8 TUBB1 missense lost rs773385727 0.0126662483953 44.8623 0.010000600009 -0.0202757 27.8967000201 rs28641769 49.1039 0.00041125812025 TUBB1 0.0000 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 2:24245713:C:G 2 24245713 G C 0.00489003 0.972585 103.526 2.6E-24 -0.141145 26.0 MFSD2B missense won rs7590516 0.145344601678 190.616 0.0789385216 0.0575185 39.6362604227 2:24210076_GATAA_G 362.242 0.030439083024 MFSD2B 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 2:53995049:T:C 2 53995049 C T 0.00291037 0.939537 33.4036 7.5E-09 0.107674 32 CHAC2 missense lost 2:53993037_TTCTTTGGTGCTCCATTGATAAGAGCACCC_T 0.0220992619492 83.1854 0.00887409216576 -0.0215314 24.2103564654 rs2542589 108.001 0.00555871642624 GPR75-ASB3 0.1450 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 2:99993019:A:G 2 99993019 G A 0.00754708 0.933772 42.4846 7.1E-11 0.0761563 27.3 EIF5B missense lost rs189480455 1.03034759134 47.5883 0.919845955396 -0.0853756 0.00963615676527 rs13008503 74.4368 0.00012210471001 EIF5B 0.0000 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 2:219892500:G:A 2 219892500 A G 0.00241675 0.814238 63.3872 1.7E-15 0.178667 24.4 CCDC108 missense lost 2:219894092:C:T 1.00807159506 66.0242 0.967809315529 0.181134 0.00102828349604 2:220165527:C:T 270.269 0.097677501156 CCDC108 0.0329 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 2:220078006:C:T 2 220078006 T C 0.00730197 0.891319 63.1784 1.9E-15 0.0936472 25.5 ABCB6 missense lost 2:220115512:T:C 1.07616900259 70.1122 0.969740440516 0.0953541 0.0883036532665 rs114969635 165.121 0.00168946482961 ABCB6 0.0096 0.0000 0.0129 0.0000 blood_RETICULOCYTE_COUNT_v2 3:48627789:C:A 3 48627789 A C 0.00767576 0.835537 64.5382 9.5E-16 0.0884484 25.0 COL7A1 missense lost 3:50326292:C:T 0.891354475206 108.701 0.529216965729 0.128156 0.201556270089 3:50329826:A:G 1756.06 0.00510160205025 COL7A1 0.0888 0.0536 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:48696521:G:A 3 48696521 A G 0.000286846 0.601227 41.3183 1.3E-10 0.40019 25.3 CELSR3 missense lost 3:48414089:CG:C 0.977179238642 49.8146 0.810513081225 0.381293 0.00544178189307 3:50329826:A:G 1756.06 0.00011220953041 CELSR3 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:49568966:C:T 3 49568966 T C 0.000734316 0.91912 66.2134 4.0E-16 -0.270874 26.8 DAG1 missense lost rs544044200 1.00322065095 72.3587 0.918018845689 0.275039 0.000171425215224 3:50329826:A:G 1756.06 0.00030295491136 DAG1 0.0001 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:49689167:G:C 3 49689167 C G 0.000171313 0.59956 39.5794 3.1E-10 0.543174 23.8 BSN missense lost 3:50326729:C:T 0.885009135241 108.612 0.322507002609 0.479437 0.138949515274 3:50329826:A:G 1756.06 0.00025693204681 BSN 0.0001 0.0000 0.0003 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50326254:G:A 3 50326254 A G 0.000650301 0.636099 98.7164 2.9E-23 0.467663 31 IFRD2 missense lost rs532400834 0.981858255586 144.676 0.669948798016 -0.481095 0.0081969806481 rs4855880 612.272 0.000126000625 IFRD2 0.0000 0.0000 0.0032 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50326271:C:T 3 50326271 T C 0.000165838 0.626809 31.9918 1.5E-08 0.560075 25.5 IFRD2 missense lost rs35761026 0.0139917590111 1708.82 0.00026194775104 -0.0854443 24.8710084348 3:50329826:A:G 1756.06 0.00025235546449 IFRD2 0.0001 0.0000 0.0012 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50326292:C:T 3 50326292 T C 0.006094 0.924251 108.701 1.9E-25 0.128156 33 IFRD2 missense lost rs11716295 0.246215923983 191.282 0.139918639249 -0.069078 27.5897196618 3:50329826:A:G 1756.06 0.012544224001 IFRD2 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50326729:C:T 3 50326729 T C 0.000534158 0.750212 108.612 2.0E-25 0.479437 26.5 IFRD2 missense won rs11716295 0.0168995533134 191.282 0.00959575017241 -0.069078 82.2087474833 3:50329826:A:G 1756.06 0.00086545402596 IFRD2 0.0045 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50327017:G:A 3 50327017 A G 9.46603e-05 0.918844 30.7485 2.9E-08 0.545928 23.4 IFRD2 missense lost rs138601391 0.0151720580159 31.9382 0.014606897881 -0.076521 23.6401306949 rs41499647 886.568 0.00017416344841 IFRD2 0.0153 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:50391167:C:T 3 50391167 T C 0.00374956 0.827988 64.4295 1.0E-15 0.136912 42 CYB561D2 stop_gained lost 3:50326292:C:T 1.06126634286 108.701 0.629036161924 0.128156 0.0586760023295 3:50329826:A:G 1756.06 0.00598665850225 XXcos-LUCA11.5 0.0003 0.0000 0.0207 0.0000 blood_RETICULOCYTE_COUNT_v2 3:51743429:T:G 3 51743429 G T 0.000183308 0.972684 41.7423 1.0E-10 0.465776 24.6 GRM2 missense lost 3:50326729:C:T 0.91227708146 108.612 0.350610831376 0.479437 0.0840330960331 3:50329826:A:G 1756.06 0.00028705169476 GRM2 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 3:52400807:G:T 3 52400807 T G 0.000756964 0.74375 64.3662 1.0E-15 0.308318 23.1 DNAH1 missense lost rs189037702 0.989662631085 131.261 0.485298929956 -0.438462 0.00172850799668 rs4855880 612.272 0.00017528965609 DNAH1 0.0020 0.0000 0.0001 0.0000 blood_RETICULOCYTE_COUNT_v2 5:38917669:T:A 5 38917669 A T 0.00451102 0.968271 44.3313 2.8E-11 0.0970302 24.0 OSMR missense won N/A N/A N/A N/A N/A N/A rs144699990 36.5705 0.852876261169 OSMR 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 5:75866423:C:T 5 75866423 T C 0.000662761 0.910187 29.9349 4.5E-08 0.219383 41 IQGAP2 stop_gained lost rs11749139 0.0121028352434 37.7372 0.00960053111329 -0.0308552 23.7107476377 rs775657371 121.093 0.00141476785956 IQGAP2 0.0904 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 5:75960968:G:C 5 75960968 C G 0.00590294 0.930086 50.8128 1.0E-12 0.0930317 27.7 IQGAP2 missense won rs250721 0.0425437765936 106.542 0.020290293136 0.0251431 32.0131270554 rs250718 108.705 0.019841257881 IQGAP2 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 6:16286061:C:A 6 16286061 A C 0.00146484 0.923729 142.226 8.7E-33 0.317328 32 GMPR missense won 6:16282518_AG_A 0.000456143244835 144.717 0.00044829169441 0.0261101 136.215688918 6:16281187:C:T 147.271 0.00043948091044 GMPR 0.0661 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 6:16290848:T:TAC 6 16290848 TAC T 0.00185807 0.936787 151.497 8.2E-35 0.284311 35 GMPR frameshift won N/A N/A N/A N/A N/A N/A 6:16281187:C:T 147.271 0.00056265737616 N/A N/A N/A N/A N/A blood_RETICULOCYTE_COUNT_v2 6:49604368:C:T 6 49604368 T C 0.000226932 0.858624 182.792 1.2E-41 0.896459 34 RHAG splice_donor won N/A N/A N/A N/A N/A N/A rs35365087 125.102 0.00010210698304 RHAG 0.0004 0.0000 0.3148 0.9729 blood_RETICULOCYTE_COUNT_v2 7:100225847:C:T 7 100225847 T C 0.00514597 0.994125 41.8496 9.9E-11 0.0819612 21.6 NONE N/A lost 7:100239422:G:A 0.987353843973 42.3164 0.976462161921 0.0804061 0.00168386621952 rs115279860 119.026 0.000128686336 TFR2 0.0014 0.0000 0.5241 0.4540 blood_RETICULOCYTE_COUNT_v2 8:41575677:G:A 8 41575677 A G 0.00134844 0.91167 69.8974 6.2E-17 0.226753 29.2 ANK1 missense won rs569451 0.00576753696034 1163.44 0.00034650333316 0.0730756 59.683917371 rs4737010 1999.94 0.00018015545284 ANK1 0.0001 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 8:86240892:C:T 8 86240892 T C 0.000239595 0.841942 32.1184 1.5E-08 0.379527 27.6 CA1 missense won 8:86111788_GTGGTGGT_G 0.000455658013345 38.7031 0.00037813524849 -0.0159929 30.7618267982 rs7829240 83.3493 0.00010189691136 CA1 0.0038 0.0076 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 8:86242013:A:G 8 86242013 G A 0.000437856 0.810343 67.2748 2.4E-16 0.405377 23.9 CA1 missense won 8:86195156_GT_G 0.000195616708336 69.1797 0.00019023029776 -0.0173388 65.4061084241 rs7829240 83.3493 0.00015477101649 CA1 0.0000 0.0000 0.0000 0.0000 blood_RETICULOCYTE_COUNT_v2 9:114886569:C:T 9 114886569 T C 0.00317559 0.888348 39.4825 3.3E-10 0.117667 25.3 SUSD1 missense won rs796133262 0.000985235108223 42.3947 0.00091755679744 0.0124537 37.0428101949 rs7856158 45.6942 0.00081358434756 SUSD1 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss blood_WHITE_COUNT_v2 10:44876292:C:T 10 44876292 T C 8.29489e-05 0.909982 32.0142 1.5E-08 0.616717 25.8 CXCL12 missense won rs1029153 0.000246164295657 45.193 0.00017437994809 -0.013633 31.0174992431 rs1029153 45.193 0.00017437994809 CXCL12 0.0000 0.0272 0.0000 0.0000 blood_WHITE_COUNT_v2 10:73515155:G:A 10 73515155 A G 0.000161255 0.762422 49.4933 2.0E-12 0.635475 22.3 C10orf54 missense won 10:73508791:T:C 0.000202324205311 83.9748 0.0001192464 -0.018352 48.0953212331 10:73508791:T:C 83.9748 0.0001192464 CDH23 0.0000 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 12:70953369:T:G 12 70953369 G T 0.00456693 0.961259 31.8973 1.6E-08 -0.0781342 22.8 PTPRB missense won rs35101303 0.000126879276269 35.5294 0.00011390865984 -0.0115999 31.182760257 rs35101303 35.5294 0.00011390865984 PTPRB 0.0000 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 12:111856181:G:A 12 111856181 A G 0.00106225 0.940356 45.3473 1.7E-11 0.207549 22.1 SH2B3 missense lost rs535526948 0.890468459262 46.0494 0.876891780625 -0.23321 0.144010887677 rs565349424 686.943 0.00062682633225 SH2B3 0.0012 0.0000 0.0181 0.0000 blood_WHITE_COUNT_v2 12:111885295:G:A 12 111885295 A G 0.000493342 0.861631 31.4139 2.1E-08 0.276964 32 SH2B3 missense lost 12:110738448_CT_C 0.00343915488982 77.9344 0.00138625905625 -0.0268073 27.8374443981 12:112850727_CAAAT_C 545.29 0.00019710475236 SH2B3 0.0001 0.0000 0.0001 0.0000 blood_WHITE_COUNT_v2 12:111885310:G:A 12 111885310 A G 0.00200609 0.885884 189.755 3.6E-43 0.31436 32 SH2B3 missense lost rs570074821 0.981531501569 196.191 0.949332589569 -0.307896 0.0163318302497 rs565349424 686.943 0.00102138407281 SH2B3 0.0004 0.0000 0.0012 0.0000 blood_WHITE_COUNT_v2 17:16852187:A:G 17 16852187 G A 0.00697349 0.947032 91.9075 9.1E-22 -0.110515 26.1 TNFRSF13B missense won rs11650406 0.00294346998034 113.059 0.00239279462244 0.0231422 82.2053729093 rs145157349 145.27 0.00147694944721 TNFRSF13B 0.0002 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 17:37822174:C:T 17 37822174 T C 0.00523694 0.969355 38.7345 4.9E-10 -0.0862709 29.6 TCAP missense lost rs535248041 0.991502581935 47.5017 0.808504890561 0.106792 0.000702203569615 17:38171668:C:G 2460.66 0.00266265288081 TCAP 0.0001 0.0000 0.0001 0.0000 blood_WHITE_COUNT_v2 17:56277684:C:T 17 56277684 T C 0.00335536 0.956261 40.7886 1.7E-10 0.109995 21.9 EPX missense lost 17:56350196:G:A 1.14067113632 51.4862 0.903666976996 0.119515 0.188728919299 rs1295926 331.56 0.00103386042369 EPX 0.0001 0.0000 0.0011 0.0000 blood_WHITE_COUNT_v2 17:56350196:G:A 17 56350196 A G 0.00355768 0.944163 51.4862 7.2E-13 0.119515 32 MPO missense won rs35527389 0.00805132565215 287.682 0.00144093882409 -0.0339087 42.6611032006 rs1295926 331.56 0.00102139685649 MPO 0.0077 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 17:56351017:C:T 17 56351017 T C 0.00128859 0.898067 32.8065 1.0E-08 0.160997 24.2 MPO missense won rs541555827 0.00226979684669 276.91 0.00026891080225 -0.0328605 29.7550042845 rs1295926 331.56 0.00019318498081 MPO 0.5760 0.0208 0.0001 0.0000 blood_WHITE_COUNT_v2 17:72758167:G:A 17 72758167 A G 0.00449358 0.935543 48.4011 3.5E-12 0.104238 32 SLC9A3R1 missense won rs4789094 0.00580705315762 58.7587 0.00478342374129 0.014819 41.3054506623 rs2084312 144.475 0.00031062300025 SLC9A3R1 0.0006 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 17:72759559:C:G 17 72759559 G C 0.00133011 0.923027 93.2914 4.5E-22 0.280029 24.1 SLC9A3R1 missense won rs6501732 0.000551863514585 110.074 0.00046772280361 -0.0219863 88.9597228763 rs2084312 144.475 0.00021101339169 SLC9A3R1 0.0002 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 17:74383107:CG:C 17 74383107 C CG 0.00361658 0.973727 58.881 1.7E-14 0.122798 35 SPHK1 frameshift won N/A N/A N/A N/A N/A N/A 17:74383109:T:C 58.881 1.0 N/A N/A N/A N/A N/A blood_WHITE_COUNT_v2 19:10334725:A:G 19 10334725 G A 0.00978367 0.967311 74.8492 5.1E-18 -0.086649 26.0 S1PR2 missense won rs10409243 0.00963251259953 110.587 0.00651962583364 0.0215731 60.8779818086 rs2358581 141.73 0.00251473163841 S1PR2 0.0000 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 1:173930928:G:C 1 173930928 C G 0.00667498 0.97342 44.7282 2.3E-11 -0.0780794 20.0 RC3H1 missense lost rs114017545 0.986200474255 46.7737 0.943072112161 0.0825354 0.00214418329094 rs114017545 46.7737 0.943072112161 RC3H1 0.0007 0.0000 0.0006 0.0000 blood_WHITE_COUNT_v2 22:17586757:T:C 22 17586757 C T 0.00583725 0.901863 132.125 1.4E-30 -0.151538 25.2 IL17RA missense won N/A N/A N/A N/A N/A N/A rs9606618 115.721 0.746732754769 IL17RA 0.0000 0.0000 0.0003 0.0000 blood_WHITE_COUNT_v2 22:17588658:G:A 22 17588658 A G 0.00104503 0.87878 188.981 5.3E-43 0.440725 22.4 IL17RA missense won N/A N/A N/A N/A N/A N/A rs531425523 74.2456 0.233786755225 IL17RA 0.0053 0.0000 0.0579 0.2601 blood_WHITE_COUNT_v2 22:29091856:AG:A 22 29091856 A AG 0.00250474 0.876417 131.123 2.3E-30 0.237554 35 CHEK2 frameshift won N/A N/A N/A N/A N/A N/A rs62236881 105.542 0.702347915844 N/A N/A N/A N/A N/A blood_WHITE_COUNT_v2 2:68615546:A:C 2 68615546 C A 0.00871859 0.982982 43.4756 4.3E-11 -0.069617 21.6 PLEK missense won rs535424102 0.00381157473123 53.238 0.003112635681 0.0268052 38.2731214765 rs535424102 53.238 0.003112635681 PLEK 0.0013 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 2:113539246:C:T 2 113539246 T C 0.00316281 0.917896 43.3033 4.7E-11 0.117987 22.7 IL1A missense lost rs555962557 1.01067286798 50.7266 0.862771611025 -0.112677 0.00122663376207 rs10169599 100.04 0.00132424665604 IL1A 0.0000 0.0000 0.0005 0.0000 blood_WHITE_COUNT_v2 2:218999982:G:A 2 218999982 A G 0.00286366 0.93086 407.986 1.0E-90 -0.384285 22.6 CXCR2 missense lost rs16858768 0.974778542119 418.889 0.949406640625 0.384189 0.0657135531115 rs16858768 418.889 0.949406640625 CXCR2 0.0000 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 2:219000267:G:A 2 219000267 A G 0.000387749 0.851105 91.4422 1.1E-21 -0.516302 24.9 CXCR2 missense won N/A N/A N/A N/A N/A N/A 2:219137341:G:A 88.8807 0.943085707876 CXCR2 0.0002 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 4:74702809:G:GT 4 74702809 GT G 0.00740273 0.989239 94.4329 2.5E-22 -0.108026 29.0 CXCL6 frameshift won rs74361503 0.141832693224 107.991 0.124025821929 0.0448474 36.6984251056 rs11725704 867.084 0.00250734538756 N/A N/A N/A N/A N/A blood_WHITE_COUNT_v2 4:155489608:C:T 4 155489608 T C 0.00589854 0.942434 36.2478 1.7E-09 0.0799288 25.2 FGB missense won N/A N/A N/A N/A N/A N/A rs574396207 31.3638 0.302889525316 FGB 0.0001 0.0000 0.0018 0.0004 blood_WHITE_COUNT_v2 5:131008584:C:T 5 131008584 T C 0.00347749 0.917733 29.8857 4.6E-08 -0.0922775 32 FNIP1 missense lost rs7705189 0.0233652512241 205.133 0.00340406901136 0.0285197 21.4475121933 rs2631367 240.422 0.00250677458329 FNIP1 0.0006 0.0184 0.0000 0.0000 blood_WHITE_COUNT_v2 6:31237115:CT:C 6 31237115 C CT 0.0021738 0.713161 45.166 1.8E-11 -0.166123 23.5 HLA-C frameshift lost rs3869111 0.0669461792345 88.112 0.034316451009 0.0528752 24.8172258239 rs28528859 219.64 0.00020803446756 N/A N/A N/A N/A N/A blood_WHITE_COUNT_v2 6:31605016:T:C 6 31605016 C T 0.00828083 0.99288 38.943 4.4E-10 0.0742924 29.9 PRRC2A missense lost 6:31677953:G:A 0.994293860137 39.104 0.990200127744 0.0736747 0.000317903983994 rs111940905 393.02 0.00245940613776 PRRC2A 0.0011 0.0000 0.0002 0.0000 blood_WHITE_COUNT_v2 6:32008783:C:T 6 32008783 T C 0.00821173 0.900143 78.4677 8.1E-19 -0.112863 23.8 CYP21A2 missense lost rs574307841 0.968280780785 91.6061 0.829407275524 0.104447 0.0200561261008 rs111940905 393.02 0.00348232172544 CYP21A2 0.0018 0.0000 0.0000 0.0000 blood_WHITE_COUNT_v2 6:32151458:G:A 6 32151458 A G 0.00535188 0.979931 31.2182 2.3E-08 0.0829553 26.1 AGER missense lost rs114701735 1.02818330923 37.9461 0.8458848784 -0.0850302 0.00611329842413 rs111940905 393.02 0.00485671003801 AGER 0.0865 0.0000 0.0047 0.0000 blood_WHITE_COUNT_v2 6:32363893:G:A 6 32363893 A G 0.00887505 0.977753 48.8387 2.8E-12 -0.0710884 25.5 BTNL2 missense lost rs142406849 0.96713338793 67.6554 0.698148815809 0.0951089 0.0134103613195 rs111940905 393.02 0.00478350673641 BTNL2 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss bmd_HEEL_TSCOREz 11:15199912:G:T 11 15199912 T G 0.00239396 0.946031 35.8786 2.1E-09 0.118992 23.7 INSC missense won rs4757307 0.00572203123496 62.7809 0.00327007847716 0.0145824 30.6558890075 rs7927191 119.971 0.00016171954561 INSC 0.0054 0.0016 0.0031 0.0000 bmd_HEEL_TSCOREz 11:15247307:C:A 11 15247307 A C 0.00567545 0.950555 57.896 2.8E-14 0.0921364 25.1 INSC missense won rs2028162 0.000350879171446 119.565 0.00016990340409 -0.0229036 55.7473254996 rs7927191 119.971 0.00016513792036 INSC 0.0016 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 11:15247310:T:G 11 15247310 G T 0.00567545 0.950555 57.896 2.8E-14 0.0921364 23.5 INSC missense lost 11:15247307:C:A 1.0 57.896 1.0 0.0921364 0.0 rs7927191 119.971 0.00016513792036 INSC 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 11:46880592:G:C 11 46880592 C G 0.00161939 0.871792 39.6478 3.0E-10 -0.149888 26.3 LRP4 missense lost 11:46886077:A:T 0.110505210765 62.133 0.070514678116 -0.0529555 17.669388193 rs7118404 323.339 0.00082851289921 LRP4 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 11:67814943:G:A 11 67814943 A G 0.00199768 0.906038 40.074 2.4E-10 0.133064 26.0 TCIRG1 missense lost rs533680779 0.887669478445 40.4125 0.880234251264 -0.124364 0.134056316339 11:68174189:G:A 406.458 0.00011920054041 TCIRG1 0.0003 0.0010 0.0000 0.0000 bmd_HEEL_TSCOREz 11:68191036:G:A 11 68191036 A G 0.00590049 0.958815 246.225 1.7E-55 -0.185872 24.0 LRP5 missense lost rs190308998 0.893880314562 281.747 0.781181984025 0.206357 0.732626828162 rs1060435 303.104 0.00104643192196 LRP5 0.0045 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 11:115080365:G:A 11 115080365 A G 0.00354802 0.915711 52.139 5.2E-13 -0.110999 22.7 CADM1 missense won rs6589486 0.0164986147356 244.639 0.00351628838289 0.0277245 39.6050319381 11:115044850:C:A 378.45 0.00210236922256 CADM1 0.0000 0.0175 0.0000 0.0000 bmd_HEEL_TSCOREz 12:49373496:T:G 12 49373496 G T 3.28956e-05 0.916361 33.8297 6.0E-09 -0.913241 29.5 WNT1 missense lost rs560573411 0.0114573851424 61.467 0.00630582104464 0.147992 26.9750934953 rs151024313 186.849 0.00014187430321 WNT1 0.0000 0.0000 0.0000 0.0021 bmd_HEEL_TSCOREz 12:49689404:G:T 12 49689404 T G 0.00781155 0.838957 32.5813 1.1E-08 -0.060156 26.0 PRPH missense lost 12:49189815:A:G 1.35600369437 334.396 0.132119891289 -0.0955777 0.881397841939 rs11551274 336.745 0.135966237696 PRPH 0.0005 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 12:53722141:C:T 12 53722141 T C 0.000306444 0.893054 42.1308 8.5E-11 -0.353712 31 SP7 missense won 12:54394497:C:T 0.000233388178872 71.6231 0.00013728574561 0.0163223 40.853364369 rs12300425 72.6833 0.00012806769889 SP7 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 15:51520032:A:T 15 51520032 T A 0.000106242 0.928588 32.6963 1.1E-08 -0.523858 29.3 CYP19A1 missense lost rs77958689 0.0035727765982 35.623 0.00327924586609 0.0327281 28.9044238032 rs2414098 294.915 0.000127509264 CYP19A1 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 16:4431767:C:T 16 4431767 T C 0.00507722 0.882325 38.9031 4.5E-10 -0.0891778 27.7 VASN missense lost rs142177225 1.05542575949 46.4069 0.884767865641 0.0877419 0.0290773413426 rs1045475 77.4341 0.000101707225 VASN 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 16:88782050:G:A 16 88782050 A G 0.00995303 0.908822 34.8922 3.5E-09 0.0580972 24.7 PIEZO1 missense lost 16:88803124:T:C 0.0145477159332 53.0058 0.00957634473744 0.0150789 26.9828322855 16:88846552:C:T 87.0441 0.00215338690116 PIEZO1 0.0001 0.0000 0.0001 0.0000 bmd_HEEL_TSCOREz 17:7534678:C:T 17 7534678 T C 0.00694779 0.973007 89.1593 3.6E-21 0.104281 23.4 SHBG missense won 17:7780709:G:T 0.000291719853545 107.318 0.00024235951041 -0.0282996 86.1396620233 rs146808712 154.102 0.00011781582849 SHBG 0.0000 0.0000 0.0356 0.0012 bmd_HEEL_TSCOREz 19:33482855:C:T 19 33482855 T C 0.00107347 0.908179 34.3326 4.6E-09 0.170596 LOW NONE N/A lost 19:33517515:C:T 0.181789770071 716.584 0.00870981693696 0.120272 11.2972635229 rs6510341 1076.57 0.00319012595344 RHPN2 0.9906 0.3912 0.0000 0.0000 bmd_HEEL_TSCOREz 1:41540902:G:A 1 41540902 A G 0.00440374 0.97369 36.9192 1.2E-09 -0.0869555 24.6 SCMH1 missense lost rs12041821 0.016950215333 47.2282 0.0132503121 0.015884 27.9317461221 1:41551510_CT_C 75.1369 0.004923407889 SCMH1 0.0000 0.0000 0.0000 0.0023 bmd_HEEL_TSCOREz 1:240656550:G:C 1 240656550 C G 0.00360169 0.862203 41.4822 1.2E-10 -0.105771 22.9 GREM2 missense won rs12743543 0.000842618239564 60.1195 0.00058140301129 0.0173632 39.1088724074 1:240607844_GTTTAT_G 91.3644 0.00026170827076 GREM2 0.0000 0.0000 0.0032 0.0000 bmd_HEEL_TSCOREz 2:55825844:A:G 2 55825844 G A 0.00542635 0.976523 32.1176 1.5E-08 0.0700093 29.7 SMEK2 missense lost rs549277925 0.75511676432 39.1133 0.620058603844 -0.0758148 0.55138433182 rs4305309 1627.51 0.00377701201476 PPP4R3B 0.0000 0.0000 0.0000 0.0000 bmd_HEEL_TSCOREz 4:88766218:GGAAA:G 4 88766218 G GGAAA 0.000462086 0.84906 88.0472 6.4E-21 -0.433629 22.4 MEPE frameshift lost rs181832503 0.583710509195 113.294 0.453634578576 0.340347 4.90348224303 rs11934731 346.554 0.00016607734641 N/A N/A N/A N/A N/A bmd_HEEL_TSCOREz 6:39869210:AAGG:A 6 39869210 A AAGG 0.000897373 0.89171 39.2439 3.7E-10 -0.203005 22.6 DAAM2 inframe_deletion won rs2504097 0.000848399334004 56.6626 0.00058759214409 0.0139761 36.9910571672 rs2504101 61.5442 0.00053728922025 N/A N/A N/A N/A N/A bmd_HEEL_TSCOREz 6:74533197:GA:G 6 74533197 G GA 0.000643206 0.959646 34.6742 3.9E-09 0.207831 28.0 CD109 frameshift won rs557326822 0.000532787061801 60.3742 0.00030599105476 0.0146139 33.0919616712 rs45464791 78.4919 0.00011138058369 N/A N/A N/A N/A N/A bmd_HEEL_TSCOREz 7:295970:T:A 7 295970 A T 0.00590617 0.810818 35.2681 2.9E-09 0.077442 27.7 FAM20C missense won rs62429411 0.00208573323113 38.797 0.00189601897489 -0.0118148 32.1202836943 rs62429411 38.797 0.00189601897489 FAM20C 0.0000 0.0000 0.0006 0.0000 bmd_HEEL_TSCOREz 7:2296552:A:G 7 2296552 G A 0.00376685 0.988495 34.7279 3.8E-09 -0.0885961 24.4 SNX8 missense won rs71550364 0.000842806327326 46.727 0.00062638076176 0.0120257 32.7407887522 rs71550364 46.727 0.00062638076176 SNX8 0.0000 0.0000 0.0000 0.0001 bmd_HEEL_TSCOREz 9:139835802:A:G 9 139835802 G A 0.00458628 0.683979 34.2172 4.9E-09 0.0910897 23.7 FBXW5 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A FBXW5 0.0153 0.0000 0.0082 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss body_BMIz 16:2816627:G:C 16 2816627 C G 0.00997925 0.914188 45.3728 1.6E-11 0.0685312 31 SRRM2 missense lost rs117549504 0.994376342087 47.31 0.953659668025 -0.0673313 0.000359746952797 16:4015729:C:T 139.7 0.00012338099929 SRRM2 0.0000 0.0000 0.0000 0.0000 body_BMIz 18:58039402:C:T 18 58039402 T C 9.31912e-05 0.692491 32.6368 1.1E-08 0.675945 31 MC4R missense won 18:57882787:C:A 0.00172654633651 421.201 0.00013378160896 0.0419218 29.9809178888 18:57882787:C:A 421.201 0.00013378160896 MC4R 0.0037 0.0000 0.0000 0.0000 body_BMIz 19:46180976:A:G 19 46180976 G A 0.00186442 0.930325 32.6343 1.1E-08 -0.130199 25.1 GIPR missense won 19:46196634:C:G 0.000810753368509 49.1555 0.00053825856016 -0.0135346 30.8023177964 19:46196634:C:G 49.1555 0.00053825856016 GIPR 0.0001 0.0749 0.0000 0.0000 body_BMIz 5:145895394:G:A 5 145895394 A G 0.00830106 0.97109 32.5863 1.1E-08 -0.0606613 37 GPR151 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A GPR151 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss body_HEIGHTz 10:81192496:A:C 10 81192496 C A 0.00124749 0.893092 33.0534 9.0E-09 -0.135112 26.4 ZCCHC24 missense lost rs113680152 0.0113127441841 47.6417 0.00784868421184 0.0260311 26.3961138636 rs4980067 351.461 0.00016675073424 ZCCHC24 0.0025 0.0000 0.0000 0.0000 body_HEIGHTz 10:124249044:C:T 10 124249044 T C 0.000464095 0.931435 93.822 3.5E-22 -0.347883 25.4 HTRA1 missense won rs775022047 0.000715647144719 142.14 0.00047237544964 0.0187831 88.8693695753 rs775022047 142.14 0.00047237544964 HTRA1 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 11:14666364:T:C 11 14666364 C T 0.00235477 0.993265 88.5156 5.0E-21 0.154185 27.1 PDE3B missense won rs61883647 0.00583438887088 107.096 0.00482216358724 -0.0174181 75.5098299414 rs4307686 114.124 0.00206064247249 PDE3B 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 11:14865399:C:T 11 14865399 T C 0.00106355 0.906863 62.7348 2.4E-15 0.197707 35 PDE3B stop_gained won rs11600815 0.0320619902409 116.719 0.017232863076 -0.0402225 42.2797888215 rs61885960 122.332 0.016330028521 PDE3B 0.1111 0.0139 0.0003 0.0000 body_HEIGHTz 11:27016360:G:A 11 27016360 A G 0.00426111 0.920873 40.0957 2.4E-10 -0.0775681 33 FIBIN missense won 11:28898610:T:G 0.000368289443881 40.1056 0.00036819853225 -0.00964109 38.5715241897 rs2099384 40.5512 0.000314175625 FIBIN 0.0005 0.0000 0.0001 0.0000 body_HEIGHTz 11:58919922:G:GGCAGATACTT 11 58919922 GGCAGATACTT G 0.00720042 0.94492 47.7385 4.9E-12 0.064999 31 FAM111A frameshift won rs2729356 0.00127835835609 53.785 0.00113464554025 0.0110523 44.385829114 rs201700765 111.716 0.00021034281024 N/A N/A N/A N/A N/A body_HEIGHTz 11:65306604:C:T 11 65306604 T C 0.000824921 0.579881 47.4814 5.6E-12 -0.235907 32 LTBP3 missense won 11:66381930_TTC_T 0.00621542264201 50.9438 0.00579299087689 0.04078 40.2898443207 11:67441143:G:T 349.967 0.0001201216 LTBP3 0.0019 0.0000 0.0000 0.0000 body_HEIGHTz 11:65320359:A:T 11 65320359 T A 0.00047232 0.722799 46.7465 8.1E-12 -0.280886 22.5 LTBP3 missense won rs7394937 0.00680395240944 71.8818 0.004424777361 0.0265783 39.3526904417 11:66835266_TTTTG_T 259.311 0.00035798910436 LTBP3 0.0003 0.0000 0.0000 0.0000 body_HEIGHTz 11:67198887:C:T 11 67198887 T C 0.00406333 0.653001 77.986 1.0E-18 -0.126602 25.7 RPS6KB2 missense lost rs553917782 0.537841261401 1077.4 0.038930841481 0.10641 5.54387100712 11:67024534:C:T 1309.68 0.028278794569 RPS6KB2 0.0001 0.0015 0.0000 0.0000 body_HEIGHTz 11:89182666:C:A 11 89182666 A C 0.004634 0.963072 40.2997 2.2E-10 -0.0713279 21.0 NOX4 missense lost 11:89082455_AAAAATAAAAT_A 0.0692301030546 56.351 0.049510255081 0.021445 21.8826493811 11:89224453:A:C 62.636 0.014839625124 NOX4 0.0000 0.0076 0.0000 0.0000 body_HEIGHTz 11:94533444:G:A 11 94533444 A G 0.00709243 0.926701 50.2186 1.4E-12 -0.0650997 25.3 AMOTL1 missense lost rs138325102 0.944916662502 51.087 0.928854540441 0.0652062 0.0391797099177 rs138325102 51.087 0.928854540441 AMOTL1 0.0000 0.0000 0.0302 0.0000 body_HEIGHTz 12:12630140:T:G 12 12630140 G T 0.0094377 0.922058 33.4808 7.2E-09 0.0495845 23.8 DUSP16 missense lost rs570836150 0.0701888446091 40.24 0.058399072281 -0.0156851 18.0905232243 rs775327397 144.625 0.00018293915025 DUSP16 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 12:12879031:G:A 12 12879031 A G 0.00126713 0.840638 34.7323 3.8E-09 0.130819 33 APOLD1 splice_donor won rs7330 0.00194223552081 44.8793 0.00150310514601 0.0101251 31.7383977279 rs35756741 149.708 0.00014230581264 N/A N/A N/A N/A N/A body_HEIGHTz 12:48371897:C:T 12 48371897 T C 9.92085e-05 0.969558 46.5098 9.1E-12 -0.547947 27.1 COL2A1 missense won 12:48768267:C:T 0.000329016218608 50.0771 0.00030557836864 -0.0123845 44.8378381653 rs6582623 96.0342 0.00010685977129 COL2A1 0.0001 0.0010 0.0000 0.0000 body_HEIGHTz 12:53451877:C:T 12 53451877 T C 0.0021458 0.813105 46.717 8.2E-12 -0.124336 LOW NONE N/A won rs11170394 0.000294476465737 90.7796 0.00015154348609 -0.0252983 45.127400036 rs11170394 90.7796 0.00015154348609 TNS2 0.0004 0.0001 0.9435 0.1764 body_HEIGHTz 12:56708908:CTTTACCTCCACAG:C 12 56708908 C CTTTACCTCCACAG 0.000100595 0.870278 39.6605 3.0E-10 -0.54546 29.6 CNPY2 splice_donor won N/A N/A N/A N/A N/A N/A 12:56708922:T:A 39.6605 1.0 N/A N/A N/A N/A N/A body_HEIGHTz 12:56708922:T:A 12 56708922 A T 0.000100595 0.870278 39.6605 3.0E-10 -0.54546 22.9 CNPY2 missense lost 12:56708908:CTTTACCTCCACAG:C 1.0 39.6605 1.0 -0.54546 0.0 12:56708908:CTTTACCTCCACAG:C 39.6605 1.0 RP11-977G19.10 0.0000 0.0000 0.0000 0.0012 body_HEIGHTz 14:23346279:G:A 14 23346279 A G 0.00895911 0.968247 45.9293 1.2E-11 0.0568272 25.3 LRP10 missense won rs10135780 0.00388330669751 105.646 0.00168825661456 -0.0191785 40.3833802057 14:23755607:G:A 148.701 0.00036074164624 LRP10 0.0000 0.0000 0.0782 0.0000 body_HEIGHTz 14:55227200:G:A 14 55227200 A G 0.0048454 0.952754 51.1461 8.6E-13 -0.0797857 23.1 SAMD4A missense won rs4901532 0.00360633164629 58.3166 0.00316290385609 0.0118172 45.1876228532 rs4901541 109.868 0.00108150215044 SAMD4A 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 15:41488231:G:C 15 41488231 C G 0.00851412 0.975227 73.9438 8.0E-18 -0.0706807 26.3 EXD1 missense lost rs192418250 0.872923460291 75.0862 0.859642354561 0.0770929 0.319141430735 rs3959554 167.69 0.010260474436 EXD1 0.0445 0.0085 0.0001 0.0000 body_HEIGHTz 15:63908666:A:G 15 63908666 G A 9.13565e-05 0.946066 38.699 4.9E-10 -0.511069 26.1 HERC1 missense won 15:61389972_GTTAA_G 0.000562636202501 50.4268 0.00043178346436 0.0226784 36.8848964836 rs782919 94.6244 0.00010322356801 HERC1 0.0001 0.0000 0.0000 0.0001 body_HEIGHTz 15:72190294:C:T 15 72190294 T C 0.00153798 0.824773 62.5285 2.6E-15 0.172895 32 MYO9A missense lost rs569805536 0.682026885266 99.2696 0.429598971844 -0.137413 1.89639589289 rs35364449 403.092 0.000107702884 MYO9A 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 15:72454690:A:G 15 72454690 G A 0.00748591 0.989578 110.618 7.2E-26 0.0951008 25.6 GRAMD2 missense lost rs34496917 0.998038944655 110.745 0.996894414916 -0.0950624 0.000106456372357 rs4886782 387.245 0.00072455718976 GRAMD2 0.0000 0.0036 0.0000 0.0000 body_HEIGHTz 15:72455985:ACTGT:A 15 72455985 A ACTGT 0.00269686 0.984227 53.3109 2.8E-13 0.109224 34 GRAMD2 frameshift lost rs12324499 0.557570404821 64.6461 0.459804691921 -0.0727309 3.42030272339 rs16958477 376.277 0.000222248464 N/A N/A N/A N/A N/A body_HEIGHTz 15:85366575:G:A 15 85366575 A G 0.00383202 0.932345 50.9185 9.6E-13 0.0849543 23.4 ALPK3 missense lost rs544894489 0.943348984821 60.9534 0.788043247524 -0.0968739 0.0420535338211 15:84590610_AT_A 1039.95 0.00282066147801 ALPK3 0.0000 0.1239 0.0000 0.0000 body_HEIGHTz 15:89390513:C:T 15 89390513 T C 0.00990963 0.954207 327.179 4.0E-73 -0.142801 26.7 ACAN missense lost 15:89400680:A:G 0.938767320005 939.101 0.327062747236 -0.139 0.316449645327 rs28584580 949.688 0.317123280769 ACAN 0.0007 0.0000 0.0000 0.0000 body_HEIGHTz 15:89424870:G:T 15 89424870 T G 0.00138613 0.926429 202.072 7.4E-46 -0.306777 24.0 HAPLN3 missense won rs35148461 0.00290445519723 394.187 0.00148891026496 0.0344519 180.878377423 rs530742363 574.446 0.00022317670881 HAPLN3 0.0411 0.0000 0.0001 0.0000 body_HEIGHTz 15:99454613:G:A 15 99454613 A G 0.00367909 0.960594 37.2155 1.1E-09 0.0743372 23.3 IGF1R missense lost rs34932387 0.656841752596 49.9352 0.489528313569 -0.115036 1.33701400172 15:99194896:C:G 576.988 0.00015392124225 IGF1R 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 15:100594099:T:C 15 100594099 C T 7.84725e-05 0.953697 30.7214 3.0E-08 -0.498704 LOW NONE N/A lost 15:99194896:C:G 0.0048589329715 576.988 0.00025871114025 -0.056935 26.5877385262 15:99194896:C:G 576.988 0.00025871114025 ADAMTS17 0.0000 0.0000 0.0007 0.6740 body_HEIGHTz 15:100672213:G:A 15 100672213 A G 0.000207544 0.895806 34.6204 4.0E-09 -0.355656 27.4 ADAMTS17 missense won rs62036218 0.00159083420709 163.159 0.00033755610529 0.0208769 31.9137877961 rs4467054 347.71 0.00013124680969 ADAMTS17 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 15:100672248:C:A 15 100672248 A C 0.000241652 0.983028 29.9912 4.3E-08 -0.270852 31 ADAMTS17 missense lost rs148603068 0.00381571843602 46.0112 0.00248717648656 0.0190127 26.4004350445 15:100681846:C:A 187.63 0.00012449873241 ADAMTS17 0.0000 0.0000 0.0008 0.0514 body_HEIGHTz 16:1828030:G:A 16 1828030 A G 0.00667964 0.933647 77.8745 1.1E-18 -0.0830275 23.6 SPSB3 missense won rs2238374 0.000960820754338 137.317 0.000544895649 -0.0177048 73.1215547364 16:2111230:A:G 137.73 0.00051965305681 SPSB3 0.0289 0.0035 0.0001 0.0000 body_HEIGHTz 16:4431767:C:T 16 4431767 T C 0.00506136 0.882325 34.7974 3.7E-09 -0.0651805 27.7 VASN missense lost 16:4493012:T:TA 0.141356287151 39.1695 0.1255780969 -0.0259314 13.5504108809 rs2907272 149.958 0.00010195546729 VASN 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 16:24815534:A:G 16 24815534 G A 0.00796245 0.96077 40.1272 2.4E-10 0.0548361 21.8 TNRC6A missense lost rs112114542 0.657220792703 41.342 0.637908910864 -0.0486374 1.43806609129 rs12708665 120.051 0.00306420923809 TNRC6A 0.0000 0.0000 0.0001 0.0000 body_HEIGHTz 16:50338341:C:T 16 50338341 T C 0.0035745 0.944172 40.335 2.1E-10 0.0874012 27.6 ADCY7 missense won N/A N/A N/A N/A N/A N/A 16:50988755:G:A 33.752 0.00031132132249 ADCY7 0.0004 0.0000 0.0001 0.0000 body_HEIGHTz 16:67166731:G:A 16 67166731 A G 0.00681625 0.967352 30.9692 2.6E-08 0.0492215 22.8 C16orf70 missense lost 16:67006541:C:T 0.983897391965 32.277 0.944031821769 0.0480478 0.00202385959828 rs13334364 137.548 0.00061118717284 C16orf70 0.0001 0.0480 0.0000 0.0000 body_HEIGHTz 16:78062057:G:C 16 78062057 C G 0.0016875 0.97796 96.7187 8.0E-23 0.173526 24.0 CLEC3A missense won N/A N/A N/A N/A N/A N/A rs4887952 96.3409 0.000131446225 CLEC3A 0.0000 0.0000 0.0000 0.0080 body_HEIGHTz 16:78064533:T:C 16 78064533 C T 0.0003722 0.939242 35.0521 3.2E-09 0.23004 32 CLEC3A missense won rs111622925 0.000692388007235 62.8772 0.00038598496225 -0.0125371 33.2316991385 rs35772006 105.64 0.00010506045001 CLEC3A 0.0000 0.0000 0.0004 0.0000 body_HEIGHTz 16:84900645:G:A 16 84900645 A G 0.00724514 0.978432 83.7311 5.7E-20 -0.084079 24.6 CRISPLD2 missense lost rs139119795 0.988199064696 87.1627 0.949293616489 0.084254 0.00293247028387 rs9941239 143.815 0.00127326221584 CRISPLD2 0.0001 0.0000 0.0000 0.0000 body_HEIGHTz 16:84902472:G:A 16 84902472 A G 0.000955431 0.822203 105.908 7.7E-25 -0.272092 29.5 CRISPLD2 missense lost rs757553064 0.813474395085 115.094 0.748548544969 0.369329 1.01863235442 rs757553064 115.094 0.748548544969 CRISPLD2 0.0000 0.0054 0.0000 0.0000 body_HEIGHTz 16:84907525:G:A 16 84907525 A G 0.000331618 0.781382 45.4037 1.6E-11 -0.323295 33 CRISPLD2 splice_acceptor won rs2244450 0.00109533542156 71.0129 0.00070032741769 -0.0144392 42.4480840073 16:84987679:A:C 136.03 0.00010374033609 CRISPLD2 0.7121 0.9937 0.0000 0.0000 body_HEIGHTz 16:88782050:G:A 16 88782050 A G 0.00997141 0.908822 65.4748 5.9E-16 -0.0672597 24.7 PIEZO1 missense won rs141440289 0.0482089586577 94.6985 0.0333318049 -0.0198326 39.8792724771 rs2242171 231.457 0.012937925025 PIEZO1 0.0001 0.0000 0.0001 0.0000 body_HEIGHTz 16:88782108:G:A 16 88782108 A G 0.000362157 0.862129 36.0567 1.9E-09 -0.262595 23.7 PIEZO1 missense won rs2242171 0.00308025534031 231.457 0.00047984654916 -0.0247182 32.1654666733 rs2242171 231.457 0.00047984654916 PIEZO1 0.0000 0.0000 0.0004 0.0000 body_HEIGHTz 16:88782205:G:C 16 88782205 C G 0.00144648 0.954236 104.312 1.7E-24 -0.217664 23.3 PIEZO1 missense lost rs562212325 0.993259851095 105.168 0.9851753536 0.213916 0.00118872276908 16:88804924:TC:T 303.055 0.00293274236304 PIEZO1 0.0331 0.0000 0.0001 0.0000 body_HEIGHTz 16:88798919:G:T 16 88798919 T G 0.00143564 0.936239 100.394 1.2E-23 -0.215858 22.4 PIEZO1 missense lost 16:88781091:G:C 1.02598191158 105.41 0.977159928196 -0.213226 0.0167263914899 16:88804924:TC:T 303.055 0.00286028153856 PIEZO1 0.0076 0.0000 0.0001 0.0000 body_HEIGHTz 17:7534678:C:T 17 7534678 T C 0.00696239 0.973007 58.3438 2.2E-14 -0.0762046 23.4 SHBG missense lost rs34146209 0.233705796105 72.5464 0.187952596225 0.0375622 15.5686491684 rs55749333 430.584 0.00375628023225 SHBG 0.0000 0.0000 0.0356 0.0012 body_HEIGHTz 17:28712211:C:G 17 28712211 G C 0.000197775 0.938003 30.2508 3.8E-08 -0.302768 25.6 CPD missense lost rs6505167 0.00762874013449 151.804 0.0015202201 0.029479 25.1972048558 17:27889986:T:C 297.995 0.00010057081225 CPD 0.0002 0.0000 0.0009 0.0000 body_HEIGHTz 17:29205072:T:C 17 29205072 C T 0.0044724 0.965351 33.2919 7.9E-09 0.0708879 27.6 ATAD5 missense lost rs147284737 1.00296279341 34.019 0.9815261184 -0.0699795 7.29522482674e-05 17:29206421:G:T 1199.82 0.00086190977889 ATAD5 0.0001 0.0000 0.0003 0.0000 body_HEIGHTz 17:54671835:C:A 17 54671835 A C 0.00114342 0.94313 34.7586 3.7E-09 0.144403 29.7 NOG missense lost rs227723 0.0112477365687 219.525 0.00178091596081 -0.0247587 27.776884827 rs227723 219.525 0.00178091596081 NOG 0.0010 0.0000 0.0001 0.0000 body_HEIGHTz 17:61574642:G:A 17 61574642 A G 0.00555383 0.873882 33.9004 5.8E-09 -0.0610381 22.2 ACE missense lost 17:61996174:T:G 0.610681945642 185.496 0.111605437476 -0.0681015 1.6190530151 rs3020619 774.303 0.00164036340196 CTD-2501B8.1 0.0010 0.0000 0.0001 0.0000 body_HEIGHTz 17:61995245:A:G 17 61995245 G A 4.86907e-05 0.951166 33.7191 6.4E-09 -0.676182 22.4 GH1 missense lost rs140871295 0.00448713943621 43.6246 0.00346827944241 0.0429987 29.3529793666 rs2005172 642.198 0.00011840921856 GH1 0.0129 0.0000 0.0000 0.0000 body_HEIGHTz 18:43796123:T:C 18 43796123 C T 0.00487619 0.958732 29.7562 4.9E-08 -0.0602544 27.8 C18orf25 missense lost rs140106878 0.00246792708352 39.5458 0.00185698941184 0.0142303 26.8731651088 18:44773382:A:T 85.3959 0.00036946221796 C18orf25 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 19:3382176:C:T 19 3382176 T C 0.00165315 0.909897 38.8439 4.6E-10 0.116007 26.0 NFIC missense lost rs12980469 0.0239580274918 211.416 0.00440185806225 -0.0269929 27.7497096365 rs35533339 212.895 0.003189764484 NFIC 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 19:9922084:C:T 19 9922084 T C 0.00114075 0.865637 34.4598 4.4E-09 0.142004 23.1 FBXL12 missense lost rs8112355 0.0106449427262 212.145 0.00172911262276 0.0261483 27.7158889248 rs750694586 230.512 0.00155683117489 FBXL12 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 19:51228371:C:CG 19 51228371 CG C 0.00475017 0.936725 60.1773 8.7E-15 -0.0908145 35 CLEC11A frameshift won N/A N/A N/A N/A N/A N/A rs571861482 47.5192 0.635170744576 N/A N/A N/A N/A N/A body_HEIGHTz 19:55831502:G:A 19 55831502 A G 0.00681775 0.872469 75.2983 4.0E-18 -0.0883188 22.9 TMEM150B missense lost 19:55857751:C:T 0.984635729437 88.1691 0.840900004036 -0.0903171 0.00447821324438 19:55879672:C:T 300.955 0.255061361296 TMEM150B 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 1:26136244:G:A 1 26136244 A G 0.000878516 0.861782 43.2761 4.8E-11 -0.178288 29.1 SEPN1 missense won 1:26588232_AT_A 0.00801887473181 56.8158 0.00610790703961 -0.0199229 35.8725345143 rs763307681 218.71 0.00046014111081 SEPN1 0.0209 0.0000 0.0002 0.0000 body_HEIGHTz 1:32120423:T:C 1 32120423 C T 0.00649671 0.92206 41.6057 1.1E-10 0.0649139 22.1 COL16A1 missense won rs4949224 0.0099642462752 83.9504 0.00493826641984 -0.0134357 33.714018349 rs2292989 89.901 0.00360517385761 COL16A1 0.0035 0.0000 0.6433 0.0013 body_HEIGHTz 1:32647133:C:G 1 32647133 G C 0.00352406 0.956001 52.1133 5.2E-13 -0.100735 23.6 TXLNA missense lost 1:32673514:G:C 0.9063833026 60.4649 0.7811908225 -0.121107 0.119860765712 rs684484 193.267 0.000330476041 TXLNA 0.0000 0.0000 0.0086 0.0000 body_HEIGHTz 1:41540902:G:A 1 41540902 A G 0.00439356 0.97369 165.814 6.1E-38 0.14896 24.6 SCMH1 missense won rs2885697 0.0232463202981 448.868 0.00858730262329 0.0339442 119.10609312 rs2885697 448.868 0.00858730262329 SCMH1 0.0000 0.0000 0.0000 0.0023 body_HEIGHTz 1:93303114:A:G 1 93303114 G A 0.00927365 0.959943 139.542 3.4E-32 0.0936293 22.8 RPL5 missense won rs10782948 0.00542345634558 151.89 0.00498255280384 -0.0190727 119.745904482 1:93034023:T:G 176.972 0.00198091755625 RPL5 0.0003 0.0000 0.0000 0.0000 body_HEIGHTz 1:103355059:G:T 1 103355059 T G 0.00330292 0.978502 46.0137 1.2E-11 0.0857882 23.8 COL11A1 missense lost rs370779514 0.999741301163 49.9009 0.921863058769 -0.0992724 7.69967331258e-07 rs4338381 200.364 0.00551281005289 COL11A1 0.0004 0.0000 0.0004 0.0000 body_HEIGHTz 1:103488522:C:G 1 103488522 G C 0.00185979 0.949433 32.0869 1.5E-08 0.099047 24.1 COL11A1 missense lost rs773717648 0.963829675597 41.0862 0.752717613649 -0.112114 0.0106889634199 rs4338381 200.364 0.00311039328681 COL11A1 0.0052 0.0000 0.0000 0.0000 body_HEIGHTz 1:149902342:C:T 1 149902342 T C 0.0061968 0.915878 54.5308 1.5E-13 0.080122 25.8 MTMR11 missense lost rs587602520 0.910889091599 54.8651 0.905338929049 -0.0811022 0.113363810956 rs6587723 518.284 0.004222140484 MTMR11 0.0018 0.0000 0.0000 0.0000 body_HEIGHTz 1:150526225:CCAGAGCCCAGGCCTCTGGCA:C 1 150526225 C CCAGAGCCCAGGCCTCTGGCA 0.00221185 0.80481 50.5873 1.1E-12 -0.129681 23.3 ADAMTSL4 frameshift won rs6587723 0.0120779385502 518.284 0.00117887162409 0.0352037 40.0792346494 1:149906413:T:C 865.284 0.00046111979169 N/A N/A N/A N/A N/A body_HEIGHTz 1:155166872:G:C 1 155166872 C G 0.000309996 0.973034 31.024 2.5E-08 -0.229712 25.7 THBS3 missense lost rs4590664 0.000757167089383 37.5338 0.00062584528561 0.0108897 29.340136055 rs148745415 131.313 0.00010820576484 THBS3 0.0000 0.0000 0.0000 0.0155 body_HEIGHTz 1:183495812:A:G 1 183495812 G A 0.00665712 0.912439 36.4838 1.5E-09 -0.0585548 22.9 SMG7 missense lost rs182797772 0.839421705587 39.7775 0.769914992704 0.0603783 0.256207747202 1:184035420_CTATT_C 717.719 0.00017293302016 SMG7 0.0003 0.0000 0.0000 0.0000 body_HEIGHTz 1:183914681:T:A 1 183914681 A T 0.00944773 0.930275 42.1347 8.5E-11 0.0529384 25.5 COLGALT2 missense lost rs5779193 0.0298894597279 43.5235 0.028935711025 0.0119028 28.8251105606 rs10911515 458.905 0.00031959785529 COLGALT2 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 1:212553243:AG:A 1 212553243 A AG 0.00323334 0.949499 63.3455 1.7E-15 -0.106943 34 TMEM206 frameshift lost 1:212183308_TGAA_T 0.254568245737 99.6408 0.161838853264 0.122177 15.549617204 1:212183308_TGAA_T 99.6408 0.161838853264 N/A N/A N/A N/A N/A body_HEIGHTz 1:223178026:T:C 1 223178026 C T 0.00733099 0.951324 54.4494 1.6E-13 -0.0626112 23.9 DISP1 missense won N/A N/A N/A N/A N/A N/A rs139405583 52.5303 0.862318389321 DISP1 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 1:227920314:C:T 1 227920314 T C 0.00850938 0.958495 36.3445 1.7E-09 -0.0530769 25.1 JMJD4 missense lost 1:227760823_CAG_C 0.628503695285 174.719 0.130739373241 0.0432824 1.56060361192 rs11588850 443.374 0.040266843556 JMJD4 0.0003 0.0000 0.0011 0.0000 body_HEIGHTz 20:5100338:T:A 20 5100338 A T 7.18229e-05 0.62696 32.3066 1.3E-08 -0.623544 24.4 PCNA missense won rs150759397 0.0011511980189 46.932 0.00079245065025 0.0487944 30.1515100564 rs150759397 46.932 0.00079245065025 PCNA 0.0000 0.0000 0.0001 0.0000 body_HEIGHTz 20:35885268:CAAAG:C 20 35885268 C CAAAG 8.0689e-05 0.917016 50.6699 1.1E-12 -0.611246 23.5 GHRH frameshift won 20:33642396:C:T 0.00190004104129 122.027 0.00078896383225 -0.0345998 46.3488277099 rs2425020 339.426 0.00015162720769 N/A N/A N/A N/A N/A body_HEIGHTz 2:27355487:G:A 2 27355487 A G 0.00135913 0.928397 37.8437 7.7E-10 -0.131565 28.1 PREB missense lost rs188686438 0.636953461527 38.0835 0.632942762929 0.176335 1.54274298649 2:27730940:T:C 170.202 0.00119378542144 PREB 0.0000 0.0000 0.0002 0.0000 body_HEIGHTz 2:219254672:T:C 2 219254672 C T 0.00262485 0.922546 42.5706 6.8E-11 -0.106422 26.9 SLC11A1 missense lost rs767077736 0.524494260943 46.3379 0.481852552336 0.146424 3.23769594488 2:219437476:T:C 343.175 0.002439273321 SLC11A1 0.0001 0.0000 0.0000 0.0000 body_HEIGHTz 2:219920219:G:A 2 219920219 A G 8.63116e-05 0.700935 29.9007 4.5E-08 -0.539801 23.4 IHH missense lost rs541088010 0.00580123963467 38.2299 0.00453731571216 0.0615504 25.5193355141 rs57764728 229.596 0.000606390625 IHH 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 2:219924961:G:T 2 219924961 T G 0.000378699 0.796924 37.4595 9.3E-10 -0.234148 27.6 IHH missense won rs138854808 0.00224035389239 81.6583 0.00102772818724 -0.0263428 33.9973282001 2:219437476:T:C 343.175 0.00019453554576 IHH 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 2:220078652:C:T 2 220078652 T C 0.00955384 0.916028 79.0829 6.0E-19 -0.0722626 24.1 ABCB6 missense lost rs556441729 0.562203397601 96.2873 0.461750148484 0.0641557 4.95050409981 2:219437476:T:C 343.175 0.00106302733681 ABCB6 0.0181 0.0003 0.0000 0.0000 body_HEIGHTz 2:233245390:C:T 2 233245390 T C 0.00474994 0.940614 41.3641 1.3E-10 0.0674215 22.1 ALPP missense lost 2:233094868:C:T 0.989961811186 490.751 0.083441255044 0.0925331 0.00104727883093 rs3116168 505.821 0.00108940263721 ALPP 0.0003 0.0000 0.0000 0.0000 body_HEIGHTz 3:46939587:C:T 3 46939587 T C 0.00264404 0.904517 35.0119 3.3E-09 0.0817439 23.6 PTH1R missense lost 3:48197428_CA_C 0.0237167447779 51.0215 0.016274870329 0.0183154 25.0584337726 rs56273245 221.788 0.00080631577849 PTH1R 0.0033 0.0090 0.0001 0.0000 body_HEIGHTz 3:48628920:C:T 3 48628920 T C 0.00331224 0.848293 42.6247 6.6E-11 0.0950826 24.6 COL7A1 missense lost rs142526831 0.964712612551 50.6794 0.8113865929 -0.108752 0.0135084757247 rs146381464 407.651 0.050597553721 COL7A1 0.0000 0.0000 0.0103 0.0000 body_HEIGHTz 3:49044932:G:T 3 49044932 T G 0.00639049 0.652554 54.0575 1.9E-13 -0.0858176 27.3 WDR6 missense lost rs548729726 0.634610999978 55.731 0.615554792329 0.10381 2.2358987649 rs574951773 321.665 0.00098824724496 WDR6 0.0000 0.0000 0.1055 0.0000 body_HEIGHTz 3:49450535:C:A 3 49450535 A C 0.00131945 0.517437 31.4929 2.0E-08 0.17353 23.3 TCTA missense lost 3:49450529:G:T 1.0 31.4929 1.0 0.17353 0.0 rs146381464 407.651 0.026731923001 TCTA 0.0162 0.0000 0.0000 0.0000 body_HEIGHTz 3:49847804:C:T 3 49847804 T C 0.00535845 0.837721 54.0976 1.9E-13 0.0878941 24.1 UBA7 missense lost 3:49753803:C:G 0.996676203875 54.5338 0.988704080896 0.0898351 0.00014966126638 rs574951773 321.665 0.020768844996 UBA7 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 3:120050156:G:A 3 120050156 A G 0.000165717 0.969532 83.3903 6.7E-20 0.54536 26.2 LRRC58 missense won N/A N/A N/A N/A N/A N/A rs533599006 75.0394 0.882369029025 LRRC58 0.1477 0.0000 0.0003 0.0000 body_HEIGHTz 3:142212029:C:A 3 142212029 A C 0.00107201 0.761 31.9792 1.6E-08 0.146323 33 ATR missense lost 3:141112859_CTT_C 0.00718491905389 2256.56 0.00010182222649 -0.0722843 26.7876044244 3:141112859_CTT_C 2256.56 0.00010182222649 ATR 0.0000 0.0000 0.1305 0.0000 body_HEIGHTz 3:148714249:G:C 3 148714249 C G 0.00238508 0.855878 41.7469 1.0E-10 -0.100757 32 GYG1 missense won rs2043549 0.000117314855393 42.9558 0.00011401327729 -0.0157091 40.8474596316 rs2043549 42.9558 0.00011401327729 GYG1 0.0002 0.0000 0.0006 0.1427 body_HEIGHTz 3:169831268:T:C 3 169831268 C T 0.00717208 0.945113 42.0232 9.0E-11 0.065541 25.5 PHC3 missense won rs9855086 0.000660569072084 72.1373 0.00038481099556 -0.012401 39.8908374559 rs2115959 83.3294 0.00018723269889 PHC3 0.0745 0.0000 0.0056 0.0000 body_HEIGHTz 3:172165413:AT:A 3 172165413 A AT 0.000179397 0.852891 30.4033 3.5E-08 -0.337222 35 GHSR frameshift lost rs582780 0.00122284575235 323.92 0.00011477693956 -0.0290525 28.3141196908 rs582780 323.92 0.00011477693956 N/A N/A N/A N/A N/A body_HEIGHTz 3:188327019:C:T 3 188327019 T C 0.00321129 0.785744 63.0304 2.0E-15 0.121519 28.8 LPP missense won N/A N/A N/A N/A N/A N/A rs9877579 54.0989 0.00076450038016 LPP 0.0003 0.0000 0.0000 0.0000 body_HEIGHTz 4:1705399:G:A 4 1705399 A G 0.00332969 0.943564 33.4859 7.2E-09 0.0790106 23.1 SLBP missense lost rs11731421 0.0414491527834 232.919 0.00595899083025 -0.0249335 21.2390298889 rs11731421 232.919 0.00595899083025 SLBP 0.0194 0.0215 0.0000 0.0000 body_HEIGHTz 4:1806629:C:T 4 1806629 T C 0.00441722 0.937756 65.5073 5.8E-16 -0.0997911 22.3 FGFR3 missense won rs565317080 0.0113263404814 160.814 0.00461376487009 0.0210545 52.3059923357 rs11731421 232.919 0.0014303524 FGFR3 0.0017 0.0000 0.0000 0.0000 body_HEIGHTz 4:73179445:C:T 4 73179445 T C 0.00393115 0.927122 35.8717 2.1E-09 -0.0796631 33 ADAMTS3 missense lost rs6446853 0.0114513673911 334.222 0.001229063364 0.0287822 28.6051425899 4:73515313:C:T 399.178 0.00066350032225 ADAMTS3 0.2644 0.0000 0.0000 0.0000 body_HEIGHTz 4:87683889:C:T 4 87683889 T C 0.00301087 0.952128 46.5361 9.0E-12 -0.0940948 23.5 PTPN13 missense lost 4:87630082_CCT_C 0.810112038843 150.07 0.251212466521 0.088059 0.464781883557 4:87730980:C:T 193.762 0.164038770289 PTPN13 0.0065 0.0383 0.0001 0.0000 body_HEIGHTz 4:120422407:T:G 4 120422407 G T 0.00106833 0.850766 58.7649 1.8E-14 0.194486 23.4 PDE5A missense won rs7676064 0.00053070711396 66.7789 0.00046701803236 0.0138333 56.0885433949 rs6821305 175.418 0.00010066309561 PDE5A 0.0000 0.0160 0.0000 0.0000 body_HEIGHTz 5:10761153:C:A 5 10761153 A C 0.00232197 0.862856 38.0171 7.0E-10 0.108144 36 DAP stop_gained won N/A N/A N/A N/A N/A N/A 5:10680997:G:A 35.0717 0.00017970743025 DAP 0.0000 0.0000 0.0004 0.0032 body_HEIGHTz 5:32774851:T:C 5 32774851 C T 0.000128806 0.887009 47.1898 6.4E-12 0.507707 31 NPR3 missense won rs139488561 0.0261431246741 60.0995 0.020527439076 -0.0912964 33.1634064001 rs10059884 557.056 0.00018999038569 NPR3 0.0000 0.0064 0.0000 0.0000 body_HEIGHTz 5:32774853:C:T 5 32774853 T C 0.000128806 0.887009 47.1898 6.4E-12 0.507707 29.5 NPR3 missense lost 5:32774851:T:C 1.0 47.1898 1.0 0.507707 0.0 rs10059884 557.056 0.00018999038569 NPR3 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 5:32783096:G:A 5 32783096 A G 0.00366622 0.96133 51.8928 5.9E-13 0.0899562 22.6 NPR3 missense lost 5:32764892_CTCAAAAAAAAAAAAA_C 0.419254653287 253.102 0.085958616969 -0.0653176 6.4480498381 rs10059884 557.056 0.005110105225 NPR3 0.0000 0.0000 0.0006 0.0054 body_HEIGHTz 5:32784907:G:A 5 32784907 A G 0.00245639 0.928159 125.709 3.6E-29 0.176821 25.3 NPR3 missense won rs4421120 0.0241722303027 250.296 0.012140293489 -0.0330549 89.6586517045 5:32768634:A:G 288.579 0.00657469614025 NPR3 0.0341 0.0000 0.0002 0.0000 body_HEIGHTz 5:32786413:C:T 5 32786413 T C 0.00139784 0.939511 79.9306 3.9E-19 0.178155 28.8 NPR3 missense won rs771142017 0.00702707963355 166.618 0.00337105649664 -0.021613 67.09148546 rs1533015 254.368 0.00070726211136 NPR3 0.0001 0.0000 0.0001 0.0000 body_HEIGHTz 5:54830395:C:A 5 54830395 A C 0.00158912 0.905627 32.588 1.1E-08 -0.114043 23.7 NONE N/A lost 5:54976039_ATATC_A 0.0049704594491 49.1508 0.00329551772356 0.0163774 28.1549725176 rs12519149 283.672 0.00022276756516 PLPP1 0.0001 0.0000 0.5799 0.1868 body_HEIGHTz 5:64766798:G:A 5 64766798 A G 0.00257153 0.964081 102.083 5.3E-24 -0.150539 24.8 ADAMTS6 missense won rs264756 0.00295709370208 108.523 0.002781613081 -0.016595 91.2824921773 rs264758 109.904 0.00265704166225 ADAMTS6 0.0011 0.0000 0.0073 0.0000 body_HEIGHTz 5:64942912:A:C 5 64942912 C A 0.00151004 0.953562 35.0372 3.2E-09 0.111151 22.6 TRAPPC13 missense lost rs568369862 0.851063569383 38.3033 0.778493876329 -0.112335 0.210273499289 rs264758 109.904 0.00063818885376 TRAPPC13 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 5:71756519:C:A 5 71756519 A C 0.00348055 0.933426 41.1343 1.4E-10 -0.0865378 27.4 ZNF366 missense lost 5:72062249_TTTTGTTTTTTGA_T 0.0278797815591 75.5639 0.015176761636 0.0192674 28.5445299097 5:72144005:C:T 170.127 0.00021123424921 ZNF366 0.0000 0.0000 0.0001 0.0000 body_HEIGHTz 5:102338739:C:G 5 102338739 G C 0.00941438 0.948169 59.9969 9.5E-15 -0.0589923 33 PAM missense won rs34142985 0.0226237363479 60.3365 0.022496400144 0.0129487 43.3057599229 rs3756583 66.475 0.015875748001 PAM 0.1032 0.0109 0.0000 0.0000 body_HEIGHTz 5:108171409:G:T 5 108171409 T G 0.00821942 0.965102 38.3372 6.0E-10 -0.0541186 32 FER missense lost rs77586651 0.0519423958246 59.2702 0.033597423616 0.014842 22.8537597771 rs79621178 185.825 0.00073051818961 FER 0.0006 0.0006 0.0000 0.0000 body_HEIGHTz 5:127668685:G:T 5 127668685 T G 0.00658937 0.98432 219.439 1.2E-49 0.138637 24.3 FBN2 missense won N/A N/A N/A N/A N/A N/A rs17607234 186.049 0.822092196249 FBN2 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 5:172750223:C:T 5 172750223 T C 0.000578905 0.863198 32.3566 1.3E-08 -0.182963 26.6 STC2 missense lost rs35750596 0.00383884752217 79.6164 0.00156013150225 0.0166712 28.4712835339 rs249513 223.622 0.00015832685584 STC2 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 5:172755066:C:A 5 172755066 A C 0.00134207 0.88959 174.163 9.1E-40 0.28548 34 STC2 missense won N/A N/A N/A N/A N/A N/A 5:172763797:T:G 91.5882 0.00417449086609 STC2 0.0004 0.0000 0.0000 0.0024 body_HEIGHTz 6:28891348:T:C 6 28891348 C T 0.000425246 0.692783 30.8921 2.7E-08 -0.236119 24.5 TRIM27 missense lost 6:30105154:A:G 0.0177901263294 54.967 0.00999826007569 -0.0469952 23.2009204797 rs62396185 655.414 0.00047610803601 TRIM27 0.0031 0.0000 0.0046 0.0000 body_HEIGHTz 6:33141678:C:T 6 33141678 T C 0.000684973 0.902277 46.4748 9.3E-12 -0.215425 28.5 COL11A2 missense won rs210211 0.0131919811846 124.491 0.004924811329 -0.0278523 36.4120428773 rs13210323 380.303 0.00016751607184 COL11A2 0.0008 0.0000 0.0102 0.0000 body_HEIGHTz 6:34004293:T:C 6 34004293 C T 0.00110826 0.970129 86.5306 1.4E-20 0.212437 21.2 GRM4 missense lost 6:34214524:A:G 0.880454976526 137.524 0.553985467204 0.257703 0.329138923488 rs202228093 1237.79 0.00544925952481 GRM4 0.0013 0.0000 0.0029 0.0000 body_HEIGHTz 6:35196481:G:T 6 35196481 T G 2.97005e-05 0.81879 37.9704 7.2E-10 -0.888218 28.2 SCUBE3 missense won 6:34491013:A:G 0.00333902476974 207.607 0.00061069282884 -0.0558188 33.7089985025 6:34491013:A:G 207.607 0.00061069282884 SCUBE3 0.0000 0.0000 0.0001 0.0002 body_HEIGHTz 6:35210477:G:A 6 35210477 A G 0.000370231 0.957151 36.8394 1.3E-09 0.246054 26.0 SCUBE3 missense lost rs552207751 1.0541004586 41.7328 0.930501390625 -0.267333 0.026250531499 rs202228093 1237.79 0.00279666457225 SCUBE3 0.0055 0.0000 0.0008 0.0000 body_HEIGHTz 6:152129063:C:T 6 152129063 T C 0.00543984 0.983888 39.7158 2.9E-10 0.0654774 23.3 ESR1 missense lost rs190930099 1.04143559064 43.4582 0.951752434084 -0.0685548 0.0167028062002 rs11968025 403.891 0.00600801712996 ESR1 0.0004 0.0000 0.0000 0.0000 body_HEIGHTz 7:42187851:C:T 7 42187851 T C 0.006123 0.947807 64.2318 1.1E-15 0.0795252 28.4 GLI3 missense won N/A N/A N/A N/A N/A N/A rs577340141 44.5349 0.00048015327376 GLI3 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 7:73482987:G:A 7 73482987 A G 0.00539587 0.849671 71.0823 3.4E-17 -0.0944654 23.3 ELN missense lost rs569265300 0.950525092334 78.4682 0.861055940761 0.0970409 0.0446087229025 rs113946216 131.158 0.00180653051089 ELN 0.0068 0.0903 0.0000 0.0000 body_HEIGHTz 7:75612866:G:C 7 75612866 C G 0.000381909 0.907457 38.4271 5.7E-10 0.271153 28.5 POR missense won 7:77137045_TG_T 0.000139280364694 41.4852 0.00012901325056 -0.0116824 37.525441141 7:77137045_TG_T 41.4852 0.00012901325056 POR 0.0825 0.0000 0.0000 0.0000 body_HEIGHTz 7:98991711:T:G 7 98991711 G T 0.00207736 0.89628 41.3837 1.3E-10 -0.102424 25.5 ARPC1B missense lost 7:98579355:G:A 0.398529555925 44.6259 0.369575237329 -0.0827065 5.62593228825 7:99332948:T:G 157.746 0.00011576253649 ARPC1B 0.0001 0.0000 0.0000 0.0069 body_HEIGHTz 8:23167180:C:T 8 23167180 T C 0.000416877 0.796077 34.6362 4.0E-09 0.244918 34 LOXL2 splice_donor won rs55865645 0.000667642528083 34.6772 0.00066685315225 -0.00986538 32.8694103284 rs2280940 91.2815 0.00015202643401 LOXL2 0.0000 0.0000 0.0002 0.9974 body_HEIGHTz 8:135614553:G:C 8 135614553 C G 0.00443342 0.938217 317.549 5.0E-71 0.210963 31 ZFAT missense lost 8:135602725_TCAC_T 0.996008450032 327.279 0.966397133025 -0.206461 0.00126736571124 rs16905190 489.379 0.00232412696464 ZFAT 0.0000 0.0000 0.0001 0.0000 body_HEIGHTz 8:135622851:G:A 8 135622851 A G 0.000795452 0.971582 97.1349 6.5E-23 0.26426 29.0 ZFAT missense won rs2439810 0.0036684669707 126.023 0.00282754872009 -0.0217043 85.7247280297 rs1036821 455.121 0.00024468154929 ZFAT 0.0000 0.0982 0.0002 0.0000 body_HEIGHTz 9:35660872:C:T 9 35660872 T C 0.000509684 0.951632 35.5926 2.4E-09 0.199324 LOW NONE N/A lost 9:35665238:G:T 1.00030905301 35.6036 1.0 0.201234 8.49764458792e-07 rs13297831 133.412 0.00037843477156 CCDC107 0.0013 0.0000 0.7490 0.0000 body_HEIGHTz 9:35674058:TG:T 9 35674058 T TG 0.00050941 0.950284 37.6568 8.4E-10 0.206615 22.9 CA9 frameshift lost 9:35800103:C:T 0.918180010929 45.1657 0.765530502916 0.250527 0.0657416452653 rs13297831 133.412 0.00038060498281 N/A N/A N/A N/A N/A body_HEIGHTz 9:35800103:C:T 9 35800103 T C 0.000439063 0.908495 45.1657 1.8E-11 0.250527 26.7 NPR2 missense won rs2890718 0.000922427215146 111.96 0.00037211567409 0.0163166 42.4638631412 rs13297831 133.412 0.00030116825764 NPR2 0.0001 0.0000 0.0000 0.0000 body_HEIGHTz 9:35802758:G:C 9 35802758 C G 3.30039e-05 0.600254 42.7933 6.1E-11 -1.08564 27.0 NPR2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A NPR2 0.0097 0.0000 0.0054 0.0000 body_HEIGHTz 9:88940359:C:T 9 88940359 T C 0.00563883 0.960914 32.4656 1.2E-08 -0.0577904 31 ZCCHC6 missense lost rs117522510 1.0473694637 35.3033 0.963181290724 0.0599866 0.0177931272279 rs374017 251.671 0.00350628595321 ZCCHC6 0.0001 0.0000 0.0000 0.0000 body_HEIGHTz 9:95221948:A:AT 9 95221948 AT A 0.00114971 0.957902 38.626 5.1E-10 -0.147803 35 ASPN frameshift lost rs529125247 0.898834535728 48.4945 0.715924131129 0.19897 0.104168327711 rs10992395 220.996 0.00097658125009 N/A N/A N/A N/A N/A body_HEIGHTz 9:98220308:G:A 9 98220308 A G 0.00172768 0.949399 41.6732 1.1E-10 0.123201 29.4 PTCH1 missense lost 9:98038382:T:C 0.0436470395341 62.7291 0.028996300089 0.0293372 26.079487014 9:98256235:T:G 581.328 0.00018099128089 PTCH1 0.0000 0.0000 0.0032 0.0036 body_HEIGHTz 9:118997772:A:C 9 118997772 C A 6.25075e-05 0.855361 39.2903 3.7E-10 -0.690101 26.3 PAPPA missense won 9:119122342:T:C 0.00104131038082 401.438 0.00010191710116 -0.0338164 36.795469205 9:119122342:T:C 401.438 0.00010191710116 PAPPA 0.0000 0.0000 0.0000 0.0000 body_HEIGHTz 9:129854158:G:A 9 129854158 A G 0.000124309 0.847461 39.1545 3.9E-10 -0.451229 28.0 ANGPTL2 missense won N/A N/A N/A N/A N/A N/A rs7035976 37.8039 0.00010049661504 RALGPS1 0.0000 0.0000 0.0001 0.0000 body_HEIGHTz 9:131671142:G:A 9 131671142 A G 0.00608706 0.907895 35.0292 3.2E-09 -0.0604523 22.9 LRRC8A missense won rs2267958 0.00350678789999 37.4193 0.00328279723849 -0.00936838 31.0033119566 rs2267958 37.4193 0.00328279723849 LRRC8A 0.0000 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss body_WHRadjBMIz 10:71883836:C:A 10 71883836 A C 0.00747713 0.887584 35.9262 2.0E-09 0.0720176 25.1 AIFM2 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A AIFM2 0.0000 0.0000 0.0008 0.0000 body_WHRadjBMIz 11:14865399:C:T 11 14865399 T C 0.00106229 0.906863 58.23 2.3E-14 -0.2496 35 PDE3B stop_gained won N/A N/A N/A N/A N/A N/A rs2970332 46.9822 0.00311675441841 PDE3B 0.1111 0.0139 0.0003 0.0000 body_WHRadjBMIz 11:14891141:G:C 11 14891141 C G 0.00658652 0.980636 35.1058 3.1E-09 -0.0722486 22.6 PDE3B missense lost rs61884005 0.0550927778297 43.439 0.044523954049 0.0200228 20.5599140688 rs2970332 46.9822 0.019868030116 PDE3B 0.0001 0.0000 0.0001 0.0000 body_WHRadjBMIz 11:64527223:G:A 11 64527223 A G 0.00405197 0.937244 35.1632 3.0E-09 0.0957249 35 PYGM stop_gained lost rs35583126 0.226897710645 93.6421 0.085201523449 -0.0603317 9.64252611371 11:64004723:G:C 163.971 0.044591924224 PYGM 0.0001 0.0000 0.0001 0.0000 body_WHRadjBMIz 15:90210353:CTTCTGCAGGGT:C 15 90210353 C CTTCTGCAGGGT 0.000294634 0.910204 44.0335 3.2E-11 -0.408169 28.7 PLIN1 frameshift won N/A N/A N/A N/A N/A N/A 15:90210367:G:C 44.0335 1.0 N/A N/A N/A N/A N/A body_WHRadjBMIz 15:90210367:G:C 15 90210367 C G 0.000294634 0.910204 44.0335 3.2E-11 -0.408169 21.3 PLIN1 missense lost 15:90210353:CTTCTGCAGGGT:C 1.0 44.0335 1.0 -0.408169 0.0 15:90210353:CTTCTGCAGGGT:C 44.0335 1.0 PLIN1 0.0243 0.0000 0.0000 0.0000 body_WHRadjBMIz 15:90214777:A:G 15 90214777 G A 0.00119912 0.93376 55.0483 1.2E-13 -0.221315 30 PLIN1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A PLIN1 0.0192 0.0000 0.0000 0.0000 body_WHRadjBMIz 2:158406865:A:G 2 158406865 G A 0.00245221 0.935012 31.3772 2.1E-08 -0.118435 27.2 ACVR1C missense lost 2:158357452_TA_T 0.0123330520711 32.3404 0.011965734544 0.016722 24.7950322251 2:158357452_TA_T 32.3404 0.011965734544 ACVR1C 0.0000 0.0000 0.0130 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss bp_DIASTOLICadjMEDz 11:14865399:C:T 11 14865399 T C 0.00107302 0.906863 30.9847 2.6E-08 -0.17841 35 PDE3B stop_gained lost rs55712837 0.00211241168944 35.5823 0.001839466321 0.0125601 28.2019780838 11:13265704_CT_C 47.1931 0.00055018862721 PDE3B 0.1111 0.0139 0.0003 0.0000 bp_DIASTOLICadjMEDz 16:2086421:C:T 16 2086421 T C 0.00678592 0.956889 95.882 1.2E-22 -0.124939 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A rs28590346 60.7241 0.00280695457249 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 bp_DIASTOLICadjMEDz 19:50139932:C:T 19 50139932 T C 0.00729959 0.954998 29.9588 4.4E-08 0.0635253 23.4 RRAS missense lost rs189349094 0.995529274096 30.4359 0.979923787921 -0.0634541 0.000150035126512 19:49605705:G:A 41.2524 0.00028990170225 RRAS 0.0004 0.0000 0.0003 0.0000 bp_DIASTOLICadjMEDz 1:41540902:G:A 1 41540902 A G 0.00439476 0.97369 31.3568 2.1E-08 -0.0867026 24.6 SCMH1 missense lost rs147082624 0.884233559386 32.5113 0.8528337801 0.10132 0.11162019934 rs147082624 32.5113 0.8528337801 SCMH1 0.0000 0.0000 0.0000 0.0023 bp_DIASTOLICadjMEDz 1:230840034:G:T 1 230840034 T G 0.00250097 0.940767 37.7896 7.9E-10 0.121698 23.9 AGT missense lost rs539645495 0.997095148529 38.7771 0.9717030625 -0.124059 7.98346884225e-05 1:230847562_TAAA_T 148.979 0.00365900380609 AGT 0.0004 0.0000 0.0000 0.0000 bp_DIASTOLICadjMEDz 1:236347180:C:T 1 236347180 T C 0.00079244 0.949279 30.0427 4.2E-08 -0.193815 41 GPR137B stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A GPR137B 0.0000 0.0000 0.0000 0.0370 bp_DIASTOLICadjMEDz 20:61050522:G:C 20 61050522 C G 0.00709259 0.959274 61.6114 4.2E-15 0.0952815 25.7 GATA5 missense won N/A N/A N/A N/A N/A N/A rs6062289 33.7754 0.00399700863961 GATA5 0.0000 0.0000 0.0000 0.0000 bp_DIASTOLICadjMEDz 3:53842691:CCTT:C 3 53842691 C CCTT 0.00589606 0.986427 49.8244 1.7E-12 0.0917215 22.9 CACNA1D inframe_deletion won rs3836508 0.0157144495343 77.7325 0.010072531044 -0.0188451 38.1156597468 rs3836508 77.7325 0.010072531044 N/A N/A N/A N/A N/A bp_DIASTOLICadjMEDz 3:169831268:T:C 3 169831268 C T 0.00722272 0.945113 55.2771 1.0E-13 -0.0908185 25.5 PHC3 missense won rs10513669 0.00260878482713 57.407 0.00251199435204 0.0206941 49.7746104645 rs4955658 217.721 0.000237807241 PHC3 0.0745 0.0000 0.0056 0.0000 bp_DIASTOLICadjMEDz 4:149075755:C:T 4 149075755 T C 0.00281968 0.985419 35.7724 2.2E-09 0.113337 26.8 NR3C2 missense won N/A N/A N/A N/A N/A N/A rs529627025 30.2077 0.890309247844 NR3C2 0.0003 0.0000 0.0000 0.0000 bp_DIASTOLICadjMEDz 9:136501756:G:C 9 136501756 C G 0.00456088 0.923168 87.1481 1.0E-20 -0.144451 24.8 DBH missense won N/A N/A N/A N/A N/A N/A rs11244061 85.0113 0.00021652533904 DBH 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss bp_SYSTOLICadjMEDz 12:20769270:G:A 12 20769270 A G 0.00339706 0.983459 35.7048 2.3E-09 0.104478 26.5 PDE3A missense won rs11045235 0.000969010042251 47.3095 0.00073131844041 0.0169569 33.5164941461 rs60691990 134.11 0.00025309946281 PDE3A 0.0000 0.0000 0.0004 0.0371 bp_SYSTOLICadjMEDz 12:53451877:C:T 12 53451877 T C 0.00213058 0.813105 35.1649 3.0E-09 0.141466 LOW NONE N/A won N/A N/A N/A N/A N/A N/A N/A N/A N/A TNS2 0.0004 0.0001 0.9435 0.1764 bp_SYSTOLICadjMEDz 12:114837349:C:A 12 114837349 A C 0.00486676 0.914157 29.9717 4.4E-08 -0.0830527 28.0 TBX5 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A TBX5 0.0000 0.0000 0.0001 0.0248 bp_SYSTOLICadjMEDz 16:2086421:C:T 16 2086421 T C 0.00678592 0.956889 108.743 1.8E-25 -0.131096 25.4 SLC9A3R2 missense won N/A N/A N/A N/A N/A N/A 16:2225673:C:A 67.9098 0.569357775364 SLC9A3R2 0.0007 0.0000 0.0000 0.0000 bp_SYSTOLICadjMEDz 16:31091390:C:T 16 31091390 T C 0.00870294 0.752541 34.4782 4.3E-09 -0.071291 23.3 ZNF646 missense lost rs148785451 0.858609990389 38.2171 0.774609454161 0.0720162 0.185692115493 16:30111904:C:A 40.2476 0.018322871044 ZNF646 0.0001 0.0000 0.0000 0.0000 bp_SYSTOLICadjMEDz 19:50139932:C:T 19 50139932 T C 0.00729959 0.954998 46.7597 8.0E-12 0.0811047 23.4 RRAS missense lost rs189349094 1.01265169207 48.3214 0.979923787921 -0.0812469 0.00185940765325 19:49605705:G:A 71.4506 0.00028990170225 RRAS 0.0004 0.0000 0.0003 0.0000 bp_SYSTOLICadjMEDz 1:153660532:T:A 1 153660532 A T 0.000364661 0.949917 34.9516 3.4E-09 0.2942 27.4 NPR1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A NPR1 0.0012 0.0526 0.0000 0.0000 bp_SYSTOLICadjMEDz 20:61050522:G:C 20 61050522 C G 0.00709259 0.959274 54.896 1.3E-13 0.0897508 25.7 GATA5 missense won N/A N/A N/A N/A N/A N/A rs28572127 37.4349 0.00332604804961 GATA5 0.0000 0.0000 0.0000 0.0000 bp_SYSTOLICadjMEDz 3:53842691:CCTT:C 3 53842691 C CCTT 0.00589606 0.986427 64.6077 9.1E-16 0.108037 22.9 CACNA1D inframe_deletion won rs3821843 0.00205417667978 69.9504 0.00189728194084 -0.0181441 58.8839827054 rs3821843 69.9504 0.00189728194084 N/A N/A N/A N/A N/A bp_SYSTOLICadjMEDz 3:169831268:T:C 3 169831268 C T 0.00722272 0.945113 48.0946 4.1E-12 -0.0872788 25.5 PHC3 missense won rs9855086 0.000843801473848 99.1668 0.00040923267025 0.0202102 45.3410532962 rs1290790 119.753 0.00030230081424 PHC3 0.0745 0.0000 0.0056 0.0000 bp_SYSTOLICadjMEDz 8:95264265:G:A 8 95264265 A G 0.000590036 0.955142 48.6411 3.1E-12 0.305924 43 GEM stop_gained won N/A N/A N/A N/A N/A N/A rs767105335 40.4382 0.734044551696 GEM 0.0000 0.0000 0.0009 0.0009 bp_SYSTOLICadjMEDz 8:135614553:G:C 8 135614553 C G 0.00444167 0.938217 48.7503 2.9E-12 -0.111535 31 ZFAT missense won 8:135612745:A:G 0.00314819524499 53.6671 0.00285976813824 0.0151172 43.4331357023 rs894348 54.9557 0.00272313854569 ZFAT 0.0000 0.0000 0.0001 0.0000 bp_SYSTOLICadjMEDz 9:136501756:G:C 9 136501756 C G 0.00456088 0.923168 58.5708 2.0E-14 -0.119536 24.8 DBH missense won N/A N/A N/A N/A N/A N/A rs562042962 37.2294 0.466531346961 DBH 0.0001 0.0000 0.0000 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss lung_FEV1FVCzSMOKE 12:57577915:C:T 12 57577915 T C 0.00434926 0.927709 64.3837 1.0E-15 0.133598 25.0 LRP1 missense lost rs186767801 0.774151334793 64.7824 0.769386859609 -0.155792 0.929309920641 rs186767801 64.7824 0.769386859609 LRP1 0.0040 0.0000 0.0000 0.0000 lung_FEV1FVCzSMOKE 13:96546850:G:A 13 96546850 A G 0.00322001 0.973455 30.0664 4.2E-08 -0.104497 35 UGGT2 stop_gained won N/A N/A N/A N/A N/A N/A N/A N/A N/A UGGT2 0.0264 0.0000 0.0001 0.0075 lung_FEV1FVCzSMOKE 15:86312198:C:T 15 86312198 T C 0.00366377 0.970243 31.7628 1.7E-08 -0.100878 23.3 KLHL25 missense lost 15:84512003_TA_T 0.00667651558183 88.9837 0.00238318736041 -0.0217245 26.7841913644 rs1896797 210.087 0.00034780385025 KLHL25 0.0000 0.0000 0.0000 0.0000 lung_FEV1FVCzSMOKE 16:2334358:T:C 16 2334358 C T 0.00268844 0.947372 33.2342 8.2E-09 -0.115188 26.2 ABCA3 missense lost rs145895260 0.317093778287 34.608 0.304506416041 0.101121 6.34348384012 rs145895260 34.608 0.304506416041 ABCA3 0.0066 0.0000 0.0089 0.0000 lung_FEV1FVCzSMOKE 16:2367764:T:A 16 2367764 A T 0.00638898 0.965324 74.4859 6.1E-18 -0.11729 34 ABCA3 missense won N/A N/A N/A N/A N/A N/A rs144763902 57.7102 0.823262246244 ABCA3 0.0000 0.0000 0.0001 0.0000 lung_FEV1FVCzSMOKE 17:4849267:T:A 17 4849267 A T 0.00161122 0.974863 36.637 1.4E-09 -0.151531 23.3 PFN1 missense lost 17:4849268:T:C 1.00102901438 36.6747 1.0 -0.15157 9.69347385181e-06 rs9896055 108.678 0.00010032826896 PFN1 0.0000 0.0000 0.0000 0.0000 lung_FEV1FVCzSMOKE 17:4849268:T:C 17 4849268 C T 0.00161225 0.974249 36.6747 1.4E-09 -0.15157 22.9 PFN1 missense lost rs748700817 0.947587262042 42.4761 0.818165475625 0.2115 0.0258697360394 rs9896055 108.678 0.00010032826896 PFN1 0.0004 0.0037 0.0000 0.0000 lung_FEV1FVCzSMOKE 1:218607532:G:C 1 218607532 C G 0.0066734 0.958767 76.1298 2.7E-18 -0.114371 25.9 TGFB2 missense won 1:218491068_CTT_C 0.0268254401531 101.98 0.020025646144 0.0268724 53.2342168154 1:218521609:A:G 134.014 0.00116287138081 TGFB2 0.0000 0.0000 0.0317 0.0000 lung_FEV1FVCzSMOKE 4:36126568:C:A 4 36126568 A C 0.00486076 0.934651 30.2718 3.8E-08 0.0933756 27.5 ARAP2 missense lost 4:36271840:A:G 0.000567747663583 62.3447 0.00027567289156 -0.0370554 28.8463867734 4:36271840:A:G 62.3447 0.00027567289156 ARAP2 0.0864 0.0014 0.0000 0.0000 lung_FEV1FVCzSMOKE 5:73153552:G:A 5 73153552 A G 0.00723067 0.897962 38.4602 5.6E-10 -0.0825562 32 ARHGEF28 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ARHGEF28 0.0001 0.0000 0.0000 0.0000 lung_FEV1FVCzSMOKE 6:31605016:T:C 6 31605016 C T 0.00824985 0.99288 31.098 2.5E-08 0.067603 29.9 PRRC2A missense lost 6:32159931:G:C 0.995227484422 52.2553 0.592276464025 0.100161 0.000177502868341 rs9267812 204.429 0.0198838201 PRRC2A 0.0011 0.0000 0.0002 0.0000 lung_FEV1FVCzSMOKE 6:32063460:G:A 6 32063460 A G 0.00342293 0.818934 30.8188 2.8E-08 0.110784 24.0 TNXB missense lost rs114119176 0.99556305309 51.1749 0.599552878864 -0.0989769 0.000152015991115 rs9267812 204.429 0.017842547776 TNXB 0.0000 0.0000 0.0000 0.0000 lung_FEV1FVCzSMOKE 6:32150890:C:A 6 32150890 A C 0.000428306 0.754764 30.1921 3.9E-08 0.325003 33 AGER splice_donor lost 6:32733823:C:T 0.0153819908032 136.068 0.00341310671524 0.0538228 23.1674152778 rs9275589 242.81 0.00026420226849 AGER 0.0001 0.0002 0.4609 0.9839 lung_FEV1FVCzSMOKE 6:32151458:G:A 6 32151458 A G 0.00536208 0.979931 47.1799 6.5E-12 0.0989728 26.1 AGER missense lost rs138503238 1.00034098473 52.0055 0.907519159044 -0.0997988 1.37117492537e-06 rs9267812 204.429 0.034383914041 AGER 0.0865 0.0000 0.0047 0.0000 Trait rsID Chr Pos Allele1 Allele0 A1FREQ INFO CHISQ p_value Beta CADD Gene Effect Lead Win_SNP Win_value Win_chi Win_R2 Win_Beta Adjusted_chi Largest_chi_SNP Largest_chi largest_chi_r2 Splice_Gene DS_Acceptor_Gain DS_Acceptor_Loss DS_Donor_Gain DS_Donor_Loss lung_FVCzSMOKE 17:79660609:C:G 17 79660609 G C 0.000789121 0.937194 31.9409 1.6E-08 -0.229331 29.0 HGS missense won rs9915229 0.0004613693905 40.7794 0.00036137249604 0.0137586 30.5834867312 rs757221720 52.1522 0.00018499536169 HGS 0.0000 0.0000 0.0008 0.0062 lung_FVCzSMOKE 20:61050522:G:C 20 61050522 C G 0.00702856 0.959274 74.834 5.1E-18 -0.110222 25.7 GATA5 missense won N/A N/A N/A N/A N/A N/A rs557327393 35.7896 0.306375534144 GATA5 0.0000 0.0000 0.0000 0.0000 lung_FVCzSMOKE 21:28210368:G:A 21 28210368 A G 0.00726199 0.917632 30.6485 3.1E-08 -0.070507 29.7 ADAMTS1 missense won N/A N/A N/A N/A N/A N/A N/A N/A N/A ADAMTS1 0.0000 0.0000 0.0000 0.0000