Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | p53_full_useme_maxed_cs.gct |
| Phenotype | MUT |
| GeneSet | s2.symbols.gmt#ngfPathway |
| Enrichment Score (ES) | -0.5887911 |
| Normalized Enrichment Score (NES) | -1.8582066 |
| Nominal p-value | 0.0021691974 |
| FDR q-value | 0.20577466 |
| FWER p-Value | 0.24 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 2905 | 0.125 | -0.2482 | No |
| 2 | KLK2 | KLK2 StanfordSource, GeneCards | kallikrein 2, prostatic | 3351 | 0.105 | -0.2589 | No |
| 3 | PLCG1 | PLCG1 StanfordSource, GeneCards | phospholipase C, gamma 1 (formerly subtype 148) | 3357 | 0.105 | -0.2260 | No |
| 4 | PIK3R1 | PIK3R1 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 3882 | 0.080 | -0.2526 | No |
| 5 | GRB2 | GRB2 StanfordSource, GeneCards | growth factor receptor-bound protein 2 | 4102 | 0.070 | -0.2521 | No |
| 6 | JUN | JUN StanfordSource, GeneCards | v-jun sarcoma virus 17 oncogene homolog (avian) | 5283 | 0.019 | -0.3630 | No |
| 7 | SHC1 | SHC1 StanfordSource, GeneCards | SHC (Src homology 2 domain containing) transforming protein 1 | 6401 | -0.032 | -0.4636 | No |
| 8 | HRAS | HRAS StanfordSource, GeneCards | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 7563 | -0.090 | -0.5499 | No |
| 9 | MAPK8 | MAPK8 StanfordSource, GeneCards | mitogen-activated protein kinase 8 | 7956 | -0.112 | -0.5531 | Yes |
| 10 | SOS1 | SOS1 StanfordSource, GeneCards | son of sevenless homolog 1 (Drosophila) | 8043 | -0.116 | -0.5245 | Yes |
| 11 | CSNK2A1 | CSNK2A1 StanfordSource, GeneCards | casein kinase 2, alpha 1 polypeptide | 8167 | -0.125 | -0.4968 | Yes |
| 12 | FOS | FOS StanfordSource, GeneCards | v-fos FBJ murine osteosarcoma viral oncogene homolog | 8716 | -0.163 | -0.4992 | Yes |
| 13 | RAF1 | RAF1 StanfordSource, GeneCards | v-raf-1 murine leukemia viral oncogene homolog 1 | 8728 | -0.164 | -0.4481 | Yes |
| 14 | ELK1 | ELK1 StanfordSource, GeneCards | ELK1, member of ETS oncogene family | 9250 | -0.205 | -0.4344 | Yes |
| 15 | NGFR | NGFR StanfordSource, GeneCards | nerve growth factor receptor (TNFR superfamily, member 16) | 9255 | -0.205 | -0.3694 | Yes |
| 16 | NGFB | NGFB StanfordSource, GeneCards | nerve growth factor, beta polypeptide | 9835 | -0.297 | -0.3319 | Yes |
| 17 | DPM2 | DPM2 StanfordSource, GeneCards | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | 9984 | -0.346 | -0.2363 | Yes |
| 18 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 10023 | -0.366 | -0.1233 | Yes |
| 19 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 10067 | -0.410 | 0.0032 | Yes |
