DatasetLeukemia_collapsed.gct
PhenotypeALL
GeneSetC1.symbols.gmt#chr6p21
Enrichment Score (ES)0.35249677
Normalized Enrichment Score (NES)1.416689
Nominal p-value0.10606061
FDR q-value0.55131257
FWER p-Value0.883
Table: GSEA Results Summary

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERESCORE_ENRICHMENT
1PSMB9PSMB9
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)251.4950.0187Yes
2NFYANFYA
StanfordSource,  GeneCards
nuclear transcription factor Y, alpha261.4880.0399Yes
3KIAA0240KIAA0240
StanfordSource,  GeneCards
KIAA02401171.1620.0474Yes
4HLA-DMBHLA-DMB
StanfordSource,  GeneCards
major histocompatibility complex, class II, DM beta1591.0980.0588Yes
5HLA-DPB1HLA-DPB1
StanfordSource,  GeneCards
major histocompatibility complex, class II, DP beta 11701.0860.0733Yes
6KIAA0082KIAA0082
StanfordSource,  GeneCards
KIAA00822610.9930.0783Yes
7MICBMICB
StanfordSource,  GeneCards
MHC class I polypeptide-related sequence B2620.9930.0925Yes
8HLA-DPA1HLA-DPA1
StanfordSource,  GeneCards
major histocompatibility complex, class II, DP alpha 12670.9900.1061Yes
9BAT3BAT3
StanfordSource,  GeneCards
HLA-B associated transcript 33100.9550.1155Yes
10HLA-DQB1HLA-DQB1
StanfordSource,  GeneCards
major histocompatibility complex, class II, DQ beta 13790.9190.1217Yes
11ZNF318ZNF318
StanfordSource,  GeneCards
zinc finger protein 3183850.9160.1342Yes
12TAP1TAP1
StanfordSource,  GeneCards
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)3960.9110.1462Yes
13STK38STK38
StanfordSource,  GeneCards
serine/threonine kinase 385220.8430.1456Yes
14DOM3ZDOM3Z
StanfordSource,  GeneCards
dom-3 homolog Z (C. elegans)5280.8400.1570Yes
15BAT8BAT8
StanfordSource,  GeneCards
HLA-B associated transcript 85330.8390.1685Yes
16RGL2RGL2
StanfordSource,  GeneCards
ral guanine nucleotide dissociation stimulator-like 25710.8210.1765Yes
17LTBLTB
StanfordSource,  GeneCards
lymphotoxin beta (TNF superfamily, member 3)5910.8160.1862Yes
18ITPR3ITPR3
StanfordSource,  GeneCards
inositol 1,4,5-triphosphate receptor, type 36270.8020.1940Yes
19LSM2LSM2
StanfordSource,  GeneCards
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)6620.7920.2019Yes
20RDBPRDBP
StanfordSource,  GeneCards
RD RNA binding protein7000.7770.2092Yes
21C6orf130C6orf130
StanfordSource,  GeneCards
chromosome 6 open reading frame 1307670.7550.2133Yes
22TRIM26TRIM26
StanfordSource,  GeneCards
tripartite motif-containing 267710.7530.2237Yes
23DDR1DDR1
StanfordSource,  GeneCards
discoidin domain receptor family, member 18020.7440.2312Yes
24HLA-DMAHLA-DMA
StanfordSource,  GeneCards
major histocompatibility complex, class II, DM alpha8120.7390.2408Yes
25RING1RING1
StanfordSource,  GeneCards
ring finger protein 18200.7370.2506Yes
26CCND3CCND3
StanfordSource,  GeneCards
cyclin D38550.7230.2575Yes
27ZNF76ZNF76
StanfordSource,  GeneCards
zinc finger protein 76 (expressed in testis)8580.7230.2676Yes
28TAP2TAP2
StanfordSource,  GeneCards
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)8870.7110.2749Yes
29PBX2PBX2
StanfordSource,  GeneCards
pre-B-cell leukemia transcription factor 29560.6890.2778Yes
30ZNF297ZNF297
StanfordSource,  GeneCards
zinc finger protein 2979760.6840.2856Yes
31FLOT1FLOT1
StanfordSource,  GeneCards
flotillin 19780.6830.2952Yes
32HCP5HCP5
StanfordSource,  GeneCards
HLA complex P510220.6710.3004Yes
33DAXXDAXX
StanfordSource,  GeneCards
death-associated protein 611450.6430.2973Yes
34AGERAGER
StanfordSource,  GeneCards
advanced glycosylation end product-specific receptor11920.6340.3016Yes
35VPS52VPS52
StanfordSource,  GeneCards
vacuolar protein sorting 52 (yeast)12690.6180.3028Yes
36SKIV2LSKIV2L
StanfordSource,  GeneCards
superkiller viralicidic activity 2-like (S. cerevisiae)13550.5980.3027Yes
37MICAMICA
StanfordSource,  GeneCards
MHC class I polypeptide-related sequence A14700.5730.2993Yes
38HLA-DOAHLA-DOA
StanfordSource,  GeneCards
major histocompatibility complex, class II, DO alpha15810.5500.2960Yes
39ABCF1ABCF1
StanfordSource,  GeneCards
ATP-binding cassette, sub-family F (GCN20), member 115930.5470.3027Yes
40GLO1GLO1
StanfordSource,  GeneCards
glyoxalase I16340.5410.3064Yes
41BRD2BRD2
StanfordSource,  GeneCards
bromodomain containing 216910.5280.3082Yes
42SNRPCSNRPC
StanfordSource,  GeneCards
small nuclear ribonucleoprotein polypeptide C17110.5230.3137Yes
43CLIC5CLIC5
StanfordSource,  GeneCards
chloride intracellular channel 517570.5160.3165Yes
44ANKS1ANKS1
StanfordSource,  GeneCards
ankyrin repeat and sterile alpha motif domain containing 118930.4900.3099Yes
45HCG9HCG9
StanfordSource,  GeneCards
HLA complex group 919340.4850.3127Yes
46CLPSCLPS
StanfordSource,  GeneCards
colipase, pancreatic19760.4780.3154Yes
47BTBD9BTBD9
StanfordSource,  GeneCards
BTB (POZ) domain containing 919990.4740.3199Yes
48HLA-EHLA-E
StanfordSource,  GeneCards
major histocompatibility complex, class I, E20400.4670.3225Yes
49MRPS18BMRPS18B
StanfordSource,  GeneCards
mitochondrial ribosomal protein S18B20480.4660.3285Yes
50BAT1BAT1
StanfordSource,  GeneCards
HLA-B associated transcript 120650.4620.3334Yes
51BFBF
StanfordSource,  GeneCards
B-factor, properdin20940.4570.3371Yes
52DHX16DHX16
StanfordSource,  GeneCards
DEAH (Asp-Glu-Ala-His) box polypeptide 1621670.4450.3362Yes
53MSH5MSH5
StanfordSource,  GeneCards
mutS homolog 5 (E. coli)21790.4430.3414Yes
54RDSRDS
StanfordSource,  GeneCards
retinal degeneration, slow22130.4370.3442Yes
55MEAMEA
StanfordSource,  GeneCards
male-enhanced antigen22430.4330.3475Yes
56MDC1MDC1
StanfordSource,  GeneCards
mediator of DNA damage checkpoint 122550.4310.3525Yes
57HLA-DOBHLA-DOB
StanfordSource,  GeneCards
major histocompatibility complex, class II, DO beta26240.3730.3206No
58DDAH2DDAH2
StanfordSource,  GeneCards
dimethylarginine dimethylaminohydrolase 227420.3550.3139No
59PPP1R11PPP1R11
StanfordSource,  GeneCards
protein phosphatase 1, regulatory (inhibitor) subunit 1127500.3530.3182No
60GTF2H4GTF2H4
StanfordSource,  GeneCards
general transcription factor IIH, polypeptide 4, 52kDa27650.3500.3218No
61HKE2HKE2
StanfordSource,  GeneCards
HLA class II region expressed gene KE229330.3250.3095No
62BYSLBYSL
StanfordSource,  GeneCards
bystin-like29610.3210.3114No
63PSMB8PSMB8
StanfordSource,  GeneCards
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7)29680.3200.3153No
64SRPK1SRPK1
StanfordSource,  GeneCards
SFRS protein kinase 129820.3190.3186No
65NEU1NEU1
StanfordSource,  GeneCards
sialidase 1 (lysosomal sialidase)30010.3170.3212No
66TUBB2TUBB2
StanfordSource,  GeneCards
tubulin, beta, 232110.2870.3042No
67PTK7PTK7
StanfordSource,  GeneCards
PTK7 protein tyrosine kinase 732750.2780.3018No
68MAPK13MAPK13
StanfordSource,  GeneCards
mitogen-activated protein kinase 1333440.2670.2988No
69TBCCTBCC
StanfordSource,  GeneCards
tubulin-specific chaperone c33710.2620.2999No
70MAPK14MAPK14
StanfordSource,  GeneCards
mitogen-activated protein kinase 1434130.2560.2993No
71CUL7CUL7
StanfordSource,  GeneCards
cullin 737960.2040.2637No
72RNF8RNF8
StanfordSource,  GeneCards
ring finger protein (C3HC4 type) 839710.1830.2487No
73HSD17B8HSD17B8
StanfordSource,  GeneCards
hydroxysteroid (17-beta) dehydrogenase 840000.1800.2484No
74C6orf109C6orf109
StanfordSource,  GeneCards
chromosome 6 open reading frame 10942040.1560.2302No
75HLA-DRAHLA-DRA
StanfordSource,  GeneCards
major histocompatibility complex, class II, DR alpha42190.1540.2309No
76RNF5RNF5
StanfordSource,  GeneCards
ring finger protein 542890.1440.2260No
77HSPCBHSPCB
StanfordSource,  GeneCards
heat shock 90kDa protein 1, beta43170.1400.2253No
78SRFSRF
StanfordSource,  GeneCards
serum response factor (c-fos serum response element-binding transcription factor)43370.1370.2253No
79CAPN11CAPN11
StanfordSource,  GeneCards
calpain 1146330.0990.1969No
80POLR1CPOLR1C
StanfordSource,  GeneCards
polymerase (RNA) I polypeptide C, 30kDa47740.0830.1840No
81CDKN1ACDKN1A
StanfordSource,  GeneCards
cyclin-dependent kinase inhibitor 1A (p21, Cip1)48010.0800.1825No
82TNFTNF
StanfordSource,  GeneCards
tumor necrosis factor (TNF superfamily, member 2)48550.0740.1782No
83C6orf18C6orf18
StanfordSource,  GeneCards
chromosome 6 open reading frame 1849000.0680.1747No
84PHF1PHF1
StanfordSource,  GeneCards
PHD finger protein 152480.0260.1401No
85PEX6PEX6
StanfordSource,  GeneCards
peroxisomal biogenesis factor 653310.0160.1320No
86APOBEC2APOBEC2
StanfordSource,  GeneCards
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 25484-0.0030.1167No
87C6orf11C6orf11
StanfordSource,  GeneCards
chromosome 6 open reading frame 115582-0.0150.1071No
88CYP21A2CYP21A2
StanfordSource,  GeneCards
cytochrome P450, family 21, subfamily A, polypeptide 25640-0.0210.1017No
89MOCS1MOCS1
StanfordSource,  GeneCards
molybdenum cofactor synthesis 15896-0.0540.0767No
90TULP1TULP1
StanfordSource,  GeneCards
tubby like protein 15926-0.0580.0746No
91SLC39A7SLC39A7
StanfordSource,  GeneCards
solute carrier family 39 (zinc transporter), member 75987-0.0640.0694No
92HLA-AHLA-A
StanfordSource,  GeneCards
major histocompatibility complex, class I, A6033-0.0690.0659No
93CDC5LCDC5L
StanfordSource,  GeneCards
CDC5 cell division cycle 5-like (S. pombe)6197-0.0870.0507No
94CLIC1CLIC1
StanfordSource,  GeneCards
chloride intracellular channel 16225-0.0910.0492No
95PPT2PPT2
StanfordSource,  GeneCards
palmitoyl-protein thioesterase 26360-0.1050.0372No
96SUPT3HSUPT3H
StanfordSource,  GeneCards
suppressor of Ty 3 homolog (S. cerevisiae)6363-0.1050.0385No
97TAPBPTAPBP
StanfordSource,  GeneCards
TAP binding protein (tapasin)6427-0.1120.0337No
98PPARDPPARD
StanfordSource,  GeneCards
peroxisome proliferative activated receptor, delta6486-0.1190.0295No
99PPP2R5DPPP2R5D
StanfordSource,  GeneCards
protein phosphatase 2, regulatory subunit B (B56), delta isoform6494-0.1200.0306No
100RXRBRXRB
StanfordSource,  GeneCards
retinoid X receptor, beta6582-0.1310.0236No
101MAD2L1BPMAD2L1BP
StanfordSource,  GeneCards
MAD2L1 binding protein6659-0.1400.0179No
102MDFIMDFI
StanfordSource,  GeneCards
MyoD family inhibitor6786-0.1550.0074No
103ABCC10ABCC10
StanfordSource,  GeneCards
ATP-binding cassette, sub-family C (CFTR/MRP), member 107332-0.212-0.0446No
104PPP1R10PPP1R10
StanfordSource,  GeneCards
protein phosphatase 1, regulatory subunit 107342-0.213-0.0425No
105AGPAT1AGPAT1
StanfordSource,  GeneCards
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)7382-0.218-0.0433No
106KIFC1KIFC1
StanfordSource,  GeneCards
kinesin family member C17408-0.221-0.0427No
107BAT2BAT2
StanfordSource,  GeneCards
HLA-B associated transcript 27465-0.228-0.0451No
108NOTCH4NOTCH4
StanfordSource,  GeneCards
Notch homolog 4 (Drosophila)7493-0.230-0.0446No
109AIF1AIF1
StanfordSource,  GeneCards
allograft inflammatory factor 17550-0.238-0.0468No
110MLNMLN
StanfordSource,  GeneCards
motilin7565-0.240-0.0448No
111TRIM31TRIM31
StanfordSource,  GeneCards
tripartite motif-containing 317647-0.250-0.0495No
112LTALTA
StanfordSource,  GeneCards
lymphotoxin alpha (TNF superfamily, member 1)7671-0.253-0.0482No
113SLC29A1SLC29A1
StanfordSource,  GeneCards
solute carrier family 29 (nucleoside transporters), member 17695-0.256-0.0469No
114CDSNCDSN
StanfordSource,  GeneCards
corneodesmosin7698-0.257-0.0434No
115TNRC5TNRC5
StanfordSource,  GeneCards
trinucleotide repeat containing 57727-0.262-0.0425No
116GUCA1BGUCA1B
StanfordSource,  GeneCards
guanylate cyclase activator 1B (retina)7822-0.273-0.0481No
117TAF11TAF11
StanfordSource,  GeneCards
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa7882-0.282-0.0501No
118RUNX2RUNX2
StanfordSource,  GeneCards
runt-related transcription factor 27885-0.283-0.0462No
119FKBP5FKBP5
StanfordSource,  GeneCards
FK506 binding protein 57887-0.283-0.0423No
120BAK1BAK1
StanfordSource,  GeneCards
BCL2-antagonist/killer 17891-0.283-0.0386No
121COL11A2COL11A2
StanfordSource,  GeneCards
collagen, type XI, alpha 27895-0.284-0.0349No
122RPS10RPS10
StanfordSource,  GeneCards
ribosomal protein S107952-0.292-0.0363No
123VARS2VARS2
StanfordSource,  GeneCards
valyl-tRNA synthetase 28005-0.299-0.0373No
124KLHDC3KLHDC3
StanfordSource,  GeneCards
kelch domain containing 38026-0.303-0.0351No
125NFKBIENFKBIE
StanfordSource,  GeneCards
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon8094-0.312-0.0374No
126IER3IER3
StanfordSource,  GeneCards
immediate early response 38216-0.331-0.0449No
127HMGA1HMGA1
StanfordSource,  GeneCards
high mobility group AT-hook 18336-0.353-0.0519No
128TRIM10TRIM10
StanfordSource,  GeneCards
tripartite motif-containing 108408-0.367-0.0538No
129LY6G6DLY6G6D
StanfordSource,  GeneCards
lymphocyte antigen 6 complex, locus G6D8429-0.372-0.0505No
130DSCR1L1DSCR1L1
StanfordSource,  GeneCards
Down syndrome critical region gene 1-like 18715-0.431-0.0732No
131POU5F1POU5F1
StanfordSource,  GeneCards
POU domain, class 5, transcription factor 18765-0.440-0.0719No
132NUDT3NUDT3
StanfordSource,  GeneCards
nudix (nucleoside diphosphate linked moiety X)-type motif 38921-0.473-0.0808No
133TEAD3TEAD3
StanfordSource,  GeneCards
TEA domain family member 39081-0.502-0.0897No
134ENPP4ENPP4
StanfordSource,  GeneCards
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative function)9109-0.508-0.0852No
135STK19STK19
StanfordSource,  GeneCards
serine/threonine kinase 199156-0.521-0.0825No
136LY6G6CLY6G6C
StanfordSource,  GeneCards
lymphocyte antigen 6 complex, locus G6C9182-0.529-0.0775No
137C6orf108C6orf108
StanfordSource,  GeneCards
chromosome 6 open reading frame 1089198-0.532-0.0714No
138TNXBTNXB
StanfordSource,  GeneCards
tenascin XB9201-0.533-0.0640No
139GNMTGNMT
StanfordSource,  GeneCards
glycine N-methyltransferase9271-0.550-0.0632No
140APOMAPOM
StanfordSource,  GeneCards
apolipoprotein M9319-0.565-0.0599No
141GRM4GRM4
StanfordSource,  GeneCards
glutamate receptor, metabotropic 49335-0.569-0.0533No
142PRR3PRR3
StanfordSource,  GeneCards
proline-rich polypeptide 39338-0.570-0.0454No
143DAAM2DAAM2
StanfordSource,  GeneCards
dishevelled associated activator of morphogenesis 29366-0.580-0.0399No
144CREBL1CREBL1
StanfordSource,  GeneCards
cAMP responsive element binding protein-like 19409-0.593-0.0357No
145PIM1PIM1
StanfordSource,  GeneCards
pim-1 oncogene9413-0.595-0.0275No
146GNL1GNL1
StanfordSource,  GeneCards
guanine nucleotide binding protein-like 19496-0.623-0.0269No
147ATP6V1G2ATP6V1G2
StanfordSource,  GeneCards
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 29562-0.655-0.0241No
148GUCA1AGUCA1A
StanfordSource,  GeneCards
guanylate cyclase activator 1A (retina)9801-0.769-0.0372No
149VEGFVEGF
StanfordSource,  GeneCards
vascular endothelial growth factor9812-0.775-0.0272No
150PGCPGC
StanfordSource,  GeneCards
progastricsin (pepsinogen C)9868-0.817-0.0211No
151TRIM15TRIM15
StanfordSource,  GeneCards
tripartite motif-containing 159959-0.906-0.0173No
152C2C2
StanfordSource,  GeneCards
complement component 29977-0.936-0.0057No
153GLP1RGLP1R
StanfordSource,  GeneCards
glucagon-like peptide 1 receptor9984-0.9500.0072No
Table: GSEA details [plain text format]



Fig 1: GSEA_Results   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List



Fig 2: Leukemia_collapsed.gct   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: Null Distribution for chr6p21   
Histogram of random enrichment scores (real ES = 0.35249677 )