Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Leukemia_collapsed.gct |
| Phenotype | AML |
| GeneSet | C1.symbols.gmt#chr1p36 |
| Enrichment Score (ES) | -0.2355216 |
| Normalized Enrichment Score (NES) | -1.0571829 |
| Nominal p-value | 0.36410257 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDC2L2 | CDC2L2 StanfordSource, GeneCards | cell division cycle 2-like 2 | 77 | 1.232 | 0.0186 | No |
| 2 | STMN1 | STMN1 StanfordSource, GeneCards | stathmin 1/oncoprotein 18 | 171 | 1.086 | 0.0324 | No |
| 3 | ID3 | ID3 StanfordSource, GeneCards | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 315 | 0.953 | 0.0384 | No |
| 4 | HNRPR | HNRPR StanfordSource, GeneCards | heterogeneous nuclear ribonucleoprotein R | 465 | 0.870 | 0.0420 | No |
| 5 | TNFRSF14 | TNFRSF14 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 626 | 0.802 | 0.0430 | No |
| 6 | DFFB | DFFB StanfordSource, GeneCards | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 666 | 0.791 | 0.0559 | No |
| 7 | CLCN6 | CLCN6 StanfordSource, GeneCards | chloride channel 6 | 671 | 0.789 | 0.0724 | No |
| 8 | CLSTN1 | CLSTN1 StanfordSource, GeneCards | calsyntenin 1 | 675 | 0.788 | 0.0889 | No |
| 9 | DHRS3 | DHRS3 StanfordSource, GeneCards | dehydrogenase/reductase (SDR family) member 3 | 717 | 0.773 | 0.1013 | No |
| 10 | HKR3 | HKR3 StanfordSource, GeneCards | GLI-Kruppel family member HKR3 | 745 | 0.763 | 0.1149 | No |
| 11 | FUCA1 | FUCA1 StanfordSource, GeneCards | fucosidase, alpha-L- 1, tissue | 784 | 0.750 | 0.1271 | No |
| 12 | EGFL3 | EGFL3 StanfordSource, GeneCards | EGF-like-domain, multiple 3 | 1171 | 0.638 | 0.1019 | No |
| 13 | DNAJC11 | DNAJC11 StanfordSource, GeneCards | DnaJ (Hsp40) homolog, subfamily C, member 11 | 1362 | 0.596 | 0.0955 | No |
| 14 | CTNNBIP1 | CTNNBIP1 StanfordSource, GeneCards | catenin, beta interacting protein 1 | 1512 | 0.566 | 0.0926 | No |
| 15 | PRDM2 | PRDM2 StanfordSource, GeneCards | PR domain containing 2, with ZNF domain | 1514 | 0.566 | 0.1045 | No |
| 16 | TARDBP | TARDBP StanfordSource, GeneCards | TAR DNA binding protein | 1555 | 0.557 | 0.1124 | No |
| 17 | SRRM1 | SRRM1 StanfordSource, GeneCards | serine/arginine repetitive matrix 1 | 1656 | 0.536 | 0.1138 | No |
| 18 | ALPL | ALPL StanfordSource, GeneCards | alkaline phosphatase, liver/bone/kidney | 1702 | 0.525 | 0.1205 | No |
| 19 | EIF4G3 | EIF4G3 StanfordSource, GeneCards | eukaryotic translation initiation factor 4 gamma, 3 | 1755 | 0.517 | 0.1263 | No |
| 20 | NUDC | NUDC StanfordSource, GeneCards | nuclear distribution gene C homolog (A. nidulans) | 1818 | 0.505 | 0.1308 | No |
| 21 | VPS13D | VPS13D StanfordSource, GeneCards | vacuolar protein sorting 13D (yeast) | 1880 | 0.493 | 0.1352 | No |
| 22 | EXOSC10 | EXOSC10 StanfordSource, GeneCards | exosome component 10 | 2056 | 0.464 | 0.1275 | No |
| 23 | CLIC4 | CLIC4 StanfordSource, GeneCards | chloride intracellular channel 4 | 2129 | 0.451 | 0.1299 | No |
| 24 | FRAP1 | FRAP1 StanfordSource, GeneCards | FK506 binding protein 12-rapamycin associated protein 1 | 2175 | 0.443 | 0.1349 | No |
| 25 | UBE4B | UBE4B StanfordSource, GeneCards | ubiquitination factor E4B (UFD2 homolog, yeast) | 2291 | 0.424 | 0.1323 | No |
| 26 | SDHB | SDHB StanfordSource, GeneCards | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2358 | 0.415 | 0.1346 | No |
| 27 | PEX14 | PEX14 StanfordSource, GeneCards | peroxisomal biogenesis factor 14 | 2579 | 0.381 | 0.1206 | No |
| 28 | CNR2 | CNR2 StanfordSource, GeneCards | cannabinoid receptor 2 (macrophage) | 2698 | 0.363 | 0.1164 | No |
| 29 | PLA2G5 | PLA2G5 StanfordSource, GeneCards | phospholipase A2, group V | 2736 | 0.356 | 0.1203 | No |
| 30 | HMGCL | HMGCL StanfordSource, GeneCards | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 2760 | 0.351 | 0.1255 | No |
| 31 | ZNF593 | ZNF593 StanfordSource, GeneCards | zinc finger protein 593 | 2889 | 0.331 | 0.1197 | No |
| 32 | PRKCZ | PRKCZ StanfordSource, GeneCards | protein kinase C, zeta | 3119 | 0.300 | 0.1030 | No |
| 33 | HES2 | HES2 StanfordSource, GeneCards | hairy and enhancer of split (Drosophila) homolog 2 | 3164 | 0.295 | 0.1049 | No |
| 34 | ELA3A | ELA3A StanfordSource, GeneCards | elastase 3A, pancreatic (protease E) | 3189 | 0.290 | 0.1087 | No |
| 35 | SCNN1D | SCNN1D StanfordSource, GeneCards | sodium channel, nonvoltage-gated 1, delta | 3224 | 0.285 | 0.1114 | No |
| 36 | WDTC1 | WDTC1 StanfordSource, GeneCards | WD and tetratricopeptide repeats 1 | 3257 | 0.281 | 0.1141 | No |
| 37 | KIF1B | KIF1B StanfordSource, GeneCards | kinesin family member 1B | 3400 | 0.257 | 0.1053 | No |
| 38 | RPS6KA1 | RPS6KA1 StanfordSource, GeneCards | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 3478 | 0.247 | 0.1029 | No |
| 39 | NR0B2 | NR0B2 StanfordSource, GeneCards | nuclear receptor subfamily 0, group B, member 2 | 3497 | 0.243 | 0.1062 | No |
| 40 | PARK7 | PARK7 StanfordSource, GeneCards | Parkinson disease (autosomal recessive, early onset) 7 | 3554 | 0.235 | 0.1056 | No |
| 41 | NPPB | NPPB StanfordSource, GeneCards | natriuretic peptide precursor B | 3602 | 0.229 | 0.1058 | No |
| 42 | AKR7A3 | AKR7A3 StanfordSource, GeneCards | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 3677 | 0.220 | 0.1030 | No |
| 43 | HTR1D | HTR1D StanfordSource, GeneCards | 5-hydroxytryptamine (serotonin) receptor 1D | 3849 | 0.200 | 0.0901 | No |
| 44 | FUSIP1 | FUSIP1 StanfordSource, GeneCards | FUS interacting protein (serine-arginine rich) 1 | 4064 | 0.172 | 0.0722 | No |
| 45 | GABRD | GABRD StanfordSource, GeneCards | gamma-aminobutyric acid (GABA) A receptor, delta | 4281 | 0.146 | 0.0536 | No |
| 46 | AKR7A2 | AKR7A2 StanfordSource, GeneCards | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 4285 | 0.145 | 0.0564 | No |
| 47 | TNFRSF8 | TNFRSF8 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 8 | 4470 | 0.121 | 0.0404 | No |
| 48 | SLC2A5 | SLC2A5 StanfordSource, GeneCards | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 4489 | 0.117 | 0.0411 | No |
| 49 | EPHA2 | EPHA2 StanfordSource, GeneCards | EphA2 | 4630 | 0.099 | 0.0291 | No |
| 50 | G1P2 | G1P2 StanfordSource, GeneCards | interferon, alpha-inducible protein (clone IFI-15K) | 4632 | 0.099 | 0.0312 | No |
| 51 | PAFAH2 | PAFAH2 StanfordSource, GeneCards | platelet-activating factor acetylhydrolase 2, 40kDa | 4820 | 0.078 | 0.0140 | No |
| 52 | ZBTB17 | ZBTB17 StanfordSource, GeneCards | zinc finger and BTB domain containing 17 | 4876 | 0.070 | 0.0100 | No |
| 53 | C1QB | C1QB StanfordSource, GeneCards | complement component 1, q subcomponent, beta polypeptide | 4943 | 0.062 | 0.0046 | No |
| 54 | MFN2 | MFN2 StanfordSource, GeneCards | mitofusin 2 | 5068 | 0.048 | -0.0068 | No |
| 55 | MSTP9 | MSTP9 StanfordSource, GeneCards | macrophage stimulating, pseudogene 9 | 5093 | 0.046 | -0.0083 | No |
| 56 | GALE | GALE StanfordSource, GeneCards | galactose-4-epimerase, UDP- | 5224 | 0.029 | -0.0207 | No |
| 57 | CA6 | CA6 StanfordSource, GeneCards | carbonic anhydrase VI | 5261 | 0.025 | -0.0238 | No |
| 58 | RERE | RERE StanfordSource, GeneCards | arginine-glutamic acid dipeptide (RE) repeats | 5325 | 0.017 | -0.0298 | No |
| 59 | HMGN2 | HMGN2 StanfordSource, GeneCards | high-mobility group nucleosomal binding domain 2 | 5522 | -0.006 | -0.0494 | No |
| 60 | DFFA | DFFA StanfordSource, GeneCards | DNA fragmentation factor, 45kDa, alpha polypeptide | 5685 | -0.027 | -0.0651 | No |
| 61 | ICMT | ICMT StanfordSource, GeneCards | isoprenylcysteine carboxyl methyltransferase | 5733 | -0.033 | -0.0691 | No |
| 62 | E2F2 | E2F2 StanfordSource, GeneCards | E2F transcription factor 2 | 5911 | -0.056 | -0.0858 | No |
| 63 | SRM | SRM StanfordSource, GeneCards | spermidine synthase | 5932 | -0.059 | -0.0865 | No |
| 64 | HTR6 | HTR6 StanfordSource, GeneCards | 5-hydroxytryptamine (serotonin) receptor 6 | 5936 | -0.059 | -0.0856 | No |
| 65 | SFN | SFN StanfordSource, GeneCards | stratifin | 6001 | -0.066 | -0.0906 | No |
| 66 | CTRC | CTRC StanfordSource, GeneCards | chymotrypsin C (caldecrin) | 6048 | -0.071 | -0.0937 | No |
| 67 | RER1 | RER1 StanfordSource, GeneCards | RER1 homolog (S. cerevisiae) | 6149 | -0.083 | -0.1020 | No |
| 68 | G1P3 | G1P3 StanfordSource, GeneCards | interferon, alpha-inducible protein (clone IFI-6-16) | 6198 | -0.087 | -0.1050 | No |
| 69 | FCN3 | FCN3 StanfordSource, GeneCards | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) | 6247 | -0.093 | -0.1078 | No |
| 70 | PLEKHM2 | PLEKHM2 StanfordSource, GeneCards | pleckstrin homology domain containing, family M (with RUN domain) member 2 | 6278 | -0.096 | -0.1088 | No |
| 71 | ARID1A | ARID1A StanfordSource, GeneCards | AT rich interactive domain 1A (SWI- like) | 6302 | -0.098 | -0.1090 | No |
| 72 | PLA2G2A | PLA2G2A StanfordSource, GeneCards | phospholipase A2, group IIA (platelets, synovial fluid) | 6368 | -0.106 | -0.1133 | No |
| 73 | CASP9 | CASP9 StanfordSource, GeneCards | caspase 9, apoptosis-related cysteine protease | 6490 | -0.120 | -0.1229 | No |
| 74 | CHD5 | CHD5 StanfordSource, GeneCards | chromodomain helicase DNA binding protein 5 | 6522 | -0.123 | -0.1234 | No |
| 75 | KIF17 | KIF17 StanfordSource, GeneCards | kinesin family member 17 | 6558 | -0.128 | -0.1242 | No |
| 76 | CAMTA1 | CAMTA1 StanfordSource, GeneCards | calmodulin binding transcription activator 1 | 6578 | -0.130 | -0.1233 | No |
| 77 | MASP2 | MASP2 StanfordSource, GeneCards | mannan-binding lectin serine protease 2 | 6612 | -0.135 | -0.1238 | No |
| 78 | EXTL1 | EXTL1 StanfordSource, GeneCards | exostoses (multiple)-like 1 | 6730 | -0.148 | -0.1324 | No |
| 79 | PADI2 | PADI2 StanfordSource, GeneCards | peptidyl arginine deiminase, type II | 6740 | -0.149 | -0.1301 | No |
| 80 | ARHGEF16 | ARHGEF16 StanfordSource, GeneCards | Rho guanine exchange factor (GEF) 16 | 6955 | -0.174 | -0.1479 | No |
| 81 | TNFRSF4 | TNFRSF4 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 4 | 7278 | -0.206 | -0.1759 | No |
| 82 | VAMP3 | VAMP3 StanfordSource, GeneCards | vesicle-associated membrane protein 3 (cellubrevin) | 7522 | -0.234 | -0.1954 | No |
| 83 | MTHFR | MTHFR StanfordSource, GeneCards | 5,10-methylenetetrahydrofolate reductase (NADPH) | 7633 | -0.248 | -0.2012 | No |
| 84 | RHD | RHD StanfordSource, GeneCards | Rhesus blood group, D antigen | 7655 | -0.250 | -0.1979 | No |
| 85 | RAP1GA1 | RAP1GA1 StanfordSource, GeneCards | RAP1, GTPase activating protein 1 | 7702 | -0.257 | -0.1971 | No |
| 86 | RPL22 | RPL22 StanfordSource, GeneCards | ribosomal protein L22 | 7743 | -0.263 | -0.1955 | No |
| 87 | AGRN | AGRN StanfordSource, GeneCards | agrin | 7838 | -0.277 | -0.1990 | No |
| 88 | TNFRSF9 | TNFRSF9 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 9 | 7927 | -0.289 | -0.2017 | No |
| 89 | RHCE | RHCE StanfordSource, GeneCards | Rhesus blood group, CcEe antigens | 8009 | -0.300 | -0.2034 | No |
| 90 | CAPZB | CAPZB StanfordSource, GeneCards | capping protein (actin filament) muscle Z-line, beta | 8016 | -0.301 | -0.1976 | No |
| 91 | RSC1A1 | RSC1A1 StanfordSource, GeneCards | regulatory solute carrier protein, family 1, member 1 | 8248 | -0.337 | -0.2137 | No |
| 92 | EPHB2 | EPHB2 StanfordSource, GeneCards | EphB2 | 8386 | -0.363 | -0.2197 | No |
| 93 | TCEB3 | TCEB3 StanfordSource, GeneCards | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 8389 | -0.363 | -0.2122 | No |
| 94 | HSPG2 | HSPG2 StanfordSource, GeneCards | heparan sulfate proteoglycan 2 (perlecan) | 8622 | -0.410 | -0.2268 | Yes |
| 95 | PAX7 | PAX7 StanfordSource, GeneCards | paired box gene 7 | 8638 | -0.413 | -0.2194 | Yes |
| 96 | NPPA | NPPA StanfordSource, GeneCards | natriuretic peptide precursor A | 8679 | -0.424 | -0.2144 | Yes |
| 97 | MFAP2 | MFAP2 StanfordSource, GeneCards | microfibrillar-associated protein 2 | 8683 | -0.424 | -0.2057 | Yes |
| 98 | H6PD | H6PD StanfordSource, GeneCards | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 8728 | -0.433 | -0.2009 | Yes |
| 99 | CLCNKA | CLCNKA StanfordSource, GeneCards | chloride channel Ka | 8755 | -0.437 | -0.1941 | Yes |
| 100 | PIK3CD | PIK3CD StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, delta polypeptide | 8788 | -0.444 | -0.1879 | Yes |
| 101 | LYPLA2 | LYPLA2 StanfordSource, GeneCards | lysophospholipase II | 8808 | -0.449 | -0.1802 | Yes |
| 102 | GPR3 | GPR3 StanfordSource, GeneCards | G protein-coupled receptor 3 | 8815 | -0.450 | -0.1712 | Yes |
| 103 | PGD | PGD StanfordSource, GeneCards | phosphogluconate dehydrogenase | 8858 | -0.459 | -0.1656 | Yes |
| 104 | TNFRSF1B | TNFRSF1B StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 1B | 8887 | -0.466 | -0.1585 | Yes |
| 105 | WASF2 | WASF2 StanfordSource, GeneCards | WAS protein family, member 2 | 8944 | -0.476 | -0.1540 | Yes |
| 106 | PEX10 | PEX10 StanfordSource, GeneCards | peroxisome biogenesis factor 10 | 9043 | -0.496 | -0.1533 | Yes |
| 107 | SKI | SKI StanfordSource, GeneCards | v-ski sarcoma viral oncogene homolog (avian) | 9120 | -0.511 | -0.1500 | Yes |
| 108 | CNKSR1 | CNKSR1 StanfordSource, GeneCards | connector enhancer of kinase suppressor of Ras 1 | 9176 | -0.528 | -0.1443 | Yes |
| 109 | SLC9A1 | SLC9A1 StanfordSource, GeneCards | solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) | 9277 | -0.552 | -0.1425 | Yes |
| 110 | ALDH4A1 | ALDH4A1 StanfordSource, GeneCards | aldehyde dehydrogenase 4 family, member A1 | 9284 | -0.554 | -0.1313 | Yes |
| 111 | KCNAB2 | KCNAB2 StanfordSource, GeneCards | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 9492 | -0.622 | -0.1389 | Yes |
| 112 | CDA | CDA StanfordSource, GeneCards | cytidine deaminase | 9535 | -0.641 | -0.1294 | Yes |
| 113 | CORT | CORT StanfordSource, GeneCards | cortistatin | 9616 | -0.671 | -0.1231 | Yes |
| 114 | LUZP1 | LUZP1 StanfordSource, GeneCards | leucine zipper protein 1 | 9724 | -0.717 | -0.1186 | Yes |
| 115 | FGR | FGR StanfordSource, GeneCards | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 9867 | -0.816 | -0.1154 | Yes |
| 116 | TNFRSF25 | TNFRSF25 StanfordSource, GeneCards | tumor necrosis factor receptor superfamily, member 25 | 9891 | -0.839 | -0.0998 | Yes |
| 117 | NBL1 | NBL1 StanfordSource, GeneCards | neuroblastoma, suppression of tumorigenicity 1 | 9927 | -0.874 | -0.0847 | Yes |
| 118 | ECE1 | ECE1 StanfordSource, GeneCards | endothelin converting enzyme 1 | 9935 | -0.881 | -0.0666 | Yes |
| 119 | ENO1 | ENO1 StanfordSource, GeneCards | enolase 1, (alpha) | 9944 | -0.888 | -0.0484 | Yes |
| 120 | DVL1 | DVL1 StanfordSource, GeneCards | dishevelled, dsh homolog 1 (Drosophila) | 9946 | -0.889 | -0.0295 | Yes |
| 121 | WNT4 | WNT4 StanfordSource, GeneCards | wingless-type MMTV integration site family, member 4 | 9954 | -0.903 | -0.0109 | Yes |
| 122 | DDOST | DDOST StanfordSource, GeneCards | dolichyl-diphosphooligosaccharide-protein glycosyltransferase | 9999 | -0.982 | 0.0056 | Yes |
