Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Leukemia_collapsed.gct |
| Phenotype | AML |
| GeneSet | C1.symbols.gmt#chr17q25 |
| Enrichment Score (ES) | -0.30929485 |
| Normalized Enrichment Score (NES) | -1.2150882 |
| Nominal p-value | 0.18727915 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.979 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PRPSAP1 | PRPSAP1 StanfordSource, GeneCards | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 83 | 1.224 | 0.0368 | No |
| 2 | GALK1 | GALK1 StanfordSource, GeneCards | galactokinase 1 | 442 | 0.883 | 0.0336 | No |
| 3 | SFRS2 | SFRS2 StanfordSource, GeneCards | splicing factor, arginine/serine-rich 2 | 451 | 0.878 | 0.0651 | No |
| 4 | FOXK2 | FOXK2 StanfordSource, GeneCards | forkhead box K2 | 492 | 0.857 | 0.0927 | No |
| 5 | EVPL | EVPL StanfordSource, GeneCards | envoplakin | 525 | 0.841 | 0.1205 | No |
| 6 | KCTD2 | KCTD2 StanfordSource, GeneCards | potassium channel tetramerisation domain containing 2 | 707 | 0.775 | 0.1310 | No |
| 7 | GALR2 | GALR2 StanfordSource, GeneCards | galanin receptor 2 | 778 | 0.751 | 0.1517 | No |
| 8 | PSCD1 | PSCD1 StanfordSource, GeneCards | pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1) | 967 | 0.686 | 0.1582 | No |
| 9 | DDX48 | DDX48 StanfordSource, GeneCards | DEAD (Asp-Glu-Ala-Asp) box polypeptide 48 | 1202 | 0.632 | 0.1580 | No |
| 10 | ICT1 | ICT1 StanfordSource, GeneCards | immature colon carcinoma transcript 1 | 1412 | 0.587 | 0.1588 | No |
| 11 | ACOX1 | ACOX1 StanfordSource, GeneCards | acyl-Coenzyme A oxidase 1, palmitoyl | 1736 | 0.520 | 0.1456 | No |
| 12 | AZI1 | AZI1 StanfordSource, GeneCards | likely ortholog of mouse 5-azacytidine induced gene 1 | 2276 | 0.427 | 0.1074 | No |
| 13 | EVER1 | EVER1 StanfordSource, GeneCards | epidermodysplasia verruciformis 1 | 2380 | 0.412 | 0.1123 | No |
| 14 | ATP5H | ATP5H StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 2660 | 0.368 | 0.0980 | No |
| 15 | SEC14L1 | SEC14L1 StanfordSource, GeneCards | SEC14-like 1 (S. cerevisiae) | 2699 | 0.363 | 0.1075 | No |
| 16 | GGA3 | GGA3 StanfordSource, GeneCards | golgi associated, gamma adaptin ear containing, ARF binding protein 3 | 2923 | 0.327 | 0.0973 | No |
| 17 | BIRC5 | BIRC5 StanfordSource, GeneCards | baculoviral IAP repeat-containing 5 (survivin) | 2986 | 0.319 | 0.1028 | No |
| 18 | WDR45L | WDR45L StanfordSource, GeneCards | WDR45-like | 3159 | 0.296 | 0.0965 | No |
| 19 | TBCD | TBCD StanfordSource, GeneCards | tubulin-specific chaperone d | 3465 | 0.249 | 0.0752 | No |
| 20 | LGALS3BP | LGALS3BP StanfordSource, GeneCards | lectin, galactoside-binding, soluble, 3 binding protein | 3591 | 0.230 | 0.0711 | No |
| 21 | TK1 | TK1 StanfordSource, GeneCards | thymidine kinase 1, soluble | 3603 | 0.229 | 0.0785 | No |
| 22 | RAB40B | RAB40B StanfordSource, GeneCards | RAB40B, member RAS oncogene family | 3605 | 0.229 | 0.0868 | No |
| 23 | CDC42EP4 | CDC42EP4 StanfordSource, GeneCards | CDC42 effector protein (Rho GTPase binding) 4 | 3640 | 0.223 | 0.0916 | No |
| 24 | DNAH17 | DNAH17 StanfordSource, GeneCards | dynein, axonemal, heavy polypeptide 17 | 3851 | 0.199 | 0.0780 | No |
| 25 | TTYH2 | TTYH2 StanfordSource, GeneCards | tweety homolog 2 (Drosophila) | 4080 | 0.170 | 0.0614 | No |
| 26 | WBP2 | WBP2 StanfordSource, GeneCards | WW domain binding protein 2 | 4207 | 0.155 | 0.0546 | No |
| 27 | SRP68 | SRP68 StanfordSource, GeneCards | signal recognition particle 68kDa | 4222 | 0.154 | 0.0588 | No |
| 28 | CDK3 | CDK3 StanfordSource, GeneCards | cyclin-dependent kinase 3 | 4397 | 0.130 | 0.0462 | No |
| 29 | STRA13 | STRA13 StanfordSource, GeneCards | stimulated by retinoic acid 13 | 4549 | 0.110 | 0.0351 | No |
| 30 | ITGB4 | ITGB4 StanfordSource, GeneCards | integrin, beta 4 | 4787 | 0.082 | 0.0144 | No |
| 31 | CSNK1D | CSNK1D StanfordSource, GeneCards | casein kinase 1, delta | 4860 | 0.073 | 0.0099 | No |
| 32 | PTDSR | PTDSR StanfordSource, GeneCards | phosphatidylserine receptor | 4902 | 0.067 | 0.0083 | No |
| 33 | CBX4 | CBX4 StanfordSource, GeneCards | chromobox homolog 4 (Pc class homolog, Drosophila) | 4928 | 0.064 | 0.0081 | No |
| 34 | RFNG | RFNG StanfordSource, GeneCards | radical fringe homolog (Drosophila) | 5257 | 0.025 | -0.0237 | No |
| 35 | FOXJ1 | FOXJ1 StanfordSource, GeneCards | forkhead box J1 | 5263 | 0.025 | -0.0233 | No |
| 36 | LLGL2 | LLGL2 StanfordSource, GeneCards | lethal giant larvae homolog 2 (Drosophila) | 5665 | -0.025 | -0.0625 | No |
| 37 | NPTX1 | NPTX1 StanfordSource, GeneCards | neuronal pentraxin I | 5940 | -0.060 | -0.0877 | No |
| 38 | PCYT2 | PCYT2 StanfordSource, GeneCards | phosphate cytidylyltransferase 2, ethanolamine | 6053 | -0.072 | -0.0963 | No |
| 39 | PDE6G | PDE6G StanfordSource, GeneCards | phosphodiesterase 6G, cGMP-specific, rod, gamma | 6449 | -0.114 | -0.1316 | No |
| 40 | MRPL12 | MRPL12 StanfordSource, GeneCards | mitochondrial ribosomal protein L12 | 7129 | -0.192 | -0.1924 | No |
| 41 | PYCR1 | PYCR1 StanfordSource, GeneCards | pyrroline-5-carboxylate reductase 1 | 7907 | -0.286 | -0.2597 | No |
| 42 | SECTM1 | SECTM1 StanfordSource, GeneCards | secreted and transmembrane 1 | 8260 | -0.339 | -0.2824 | No |
| 43 | SOCS3 | SOCS3 StanfordSource, GeneCards | suppressor of cytokine signaling 3 | 8383 | -0.362 | -0.2812 | No |
| 44 | SLC9A3R1 | SLC9A3R1 StanfordSource, GeneCards | solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 | 8582 | -0.401 | -0.2863 | No |
| 45 | AATK | AATK StanfordSource, GeneCards | apoptosis-associated tyrosine kinase | 8813 | -0.449 | -0.2927 | Yes |
| 46 | CD7 | CD7 StanfordSource, GeneCards | CD7 antigen (p41) | 8848 | -0.457 | -0.2793 | Yes |
| 47 | SGSH | SGSH StanfordSource, GeneCards | N-sulfoglucosamine sulfohydrolase (sulfamidase) | 8914 | -0.471 | -0.2684 | Yes |
| 48 | ARHGDIA | ARHGDIA StanfordSource, GeneCards | Rho GDP dissociation inhibitor (GDI) alpha | 8945 | -0.476 | -0.2539 | Yes |
| 49 | SLC16A3 | SLC16A3 StanfordSource, GeneCards | solute carrier family 16 (monocarboxylic acid transporters), member 3 | 8981 | -0.483 | -0.2396 | Yes |
| 50 | AANAT | AANAT StanfordSource, GeneCards | arylalkylamine N-acetyltransferase | 9208 | -0.535 | -0.2424 | Yes |
| 51 | BAIAP2 | BAIAP2 StanfordSource, GeneCards | BAI1-associated protein 2 | 9378 | -0.585 | -0.2378 | Yes |
| 52 | GRIN2C | GRIN2C StanfordSource, GeneCards | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 9405 | -0.592 | -0.2186 | Yes |
| 53 | SSTR2 | SSTR2 StanfordSource, GeneCards | somatostatin receptor 2 | 9681 | -0.699 | -0.2203 | Yes |
| 54 | HGS | HGS StanfordSource, GeneCards | hepatocyte growth factor-regulated tyrosine kinase substrate | 9690 | -0.703 | -0.1952 | Yes |
| 55 | P4HB | P4HB StanfordSource, GeneCards | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) | 9756 | -0.736 | -0.1746 | Yes |
| 56 | FDXR | FDXR StanfordSource, GeneCards | ferredoxin reductase | 9811 | -0.775 | -0.1514 | Yes |
| 57 | TIMP2 | TIMP2 StanfordSource, GeneCards | tissue inhibitor of metalloproteinase 2 | 9863 | -0.815 | -0.1265 | Yes |
| 58 | RECQL5 | RECQL5 StanfordSource, GeneCards | RecQ protein-like 5 | 9917 | -0.858 | -0.1002 | Yes |
| 59 | SYNGR2 | SYNGR2 StanfordSource, GeneCards | synaptogyrin 2 | 9974 | -0.930 | -0.0715 | Yes |
| 60 | SLC16A5 | SLC16A5 StanfordSource, GeneCards | solute carrier family 16 (monocarboxylic acid transporters), member 5 | 10003 | -0.987 | -0.0379 | Yes |
| 61 | GAA | GAA StanfordSource, GeneCards | glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) | 10045 | -1.166 | 0.0010 | Yes |
