Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Gender_collapsed.gct |
| Phenotype | FEMALE |
| GeneSet | C2.symbols.gmt#rhoPathway |
| Enrichment Score (ES) | -0.4453963 |
| Normalized Enrichment Score (NES) | -1.2943203 |
| Nominal p-value | 0.17934783 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.914 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GSN | GSN StanfordSource, GeneCards | gelsolin (amyloidosis, Finnish type) | 1646 | 0.224 | -0.0529 | No |
| 2 | ARHGEF5 | ARHGEF5 StanfordSource, GeneCards | Rho guanine nucleotide exchange factor (GEF) 5 | 2194 | 0.194 | -0.0401 | No |
| 3 | ARHGEF11 | ARHGEF11 StanfordSource, GeneCards | Rho guanine nucleotide exchange factor (GEF) 11 | 2816 | 0.166 | -0.0393 | No |
| 4 | BAIAP2 | BAIAP2 StanfordSource, GeneCards | BAI1-associated protein 2 | 3265 | 0.147 | -0.0320 | No |
| 5 | ARPC4 | ARPC4 StanfordSource, GeneCards | actin related protein 2/3 complex, subunit 4, 20kDa | 3539 | 0.136 | -0.0156 | No |
| 6 | ROCK1 | ROCK1 StanfordSource, GeneCards | Rho-associated, coiled-coil containing protein kinase 1 | 6698 | 0.035 | -0.2170 | No |
| 7 | LIMK1 | LIMK1 StanfordSource, GeneCards | LIM domain kinase 1 | 6994 | 0.027 | -0.2299 | No |
| 8 | ARHGAP1 | ARHGAP1 StanfordSource, GeneCards | Rho GTPase activating protein 1 | 7042 | 0.025 | -0.2267 | No |
| 9 | OPHN1 | OPHN1 StanfordSource, GeneCards | oligophrenin 1 | 7363 | 0.015 | -0.2442 | No |
| 10 | MYLK | MYLK StanfordSource, GeneCards | myosin, light polypeptide kinase | 7607 | 0.008 | -0.2583 | No |
| 11 | VCL | VCL StanfordSource, GeneCards | vinculin | 7620 | 0.007 | -0.2572 | No |
| 12 | PIP5K1B | PIP5K1B StanfordSource, GeneCards | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 7997 | -0.004 | -0.2813 | No |
| 13 | MYL2 | MYL2 StanfordSource, GeneCards | myosin, light polypeptide 2, regulatory, cardiac, slow | 8062 | -0.006 | -0.2841 | No |
| 14 | ACTR2 | ACTR2 StanfordSource, GeneCards | ARP2 actin-related protein 2 homolog (yeast) | 8767 | -0.024 | -0.3249 | No |
| 15 | TLN1 | TLN1 StanfordSource, GeneCards | talin 1 | 8919 | -0.029 | -0.3277 | No |
| 16 | ARHGEF1 | ARHGEF1 StanfordSource, GeneCards | Rho guanine nucleotide exchange factor (GEF) 1 | 9869 | -0.057 | -0.3765 | No |
| 17 | ARHGAP6 | ARHGAP6 StanfordSource, GeneCards | Rho GTPase activating protein 6 | 10075 | -0.063 | -0.3742 | No |
| 18 | ARPC3 | ARPC3 StanfordSource, GeneCards | actin related protein 2/3 complex, subunit 3, 21kDa | 10311 | -0.070 | -0.3720 | No |
| 19 | ARHGAP5 | ARHGAP5 StanfordSource, GeneCards | Rho GTPase activating protein 5 | 10432 | -0.075 | -0.3611 | No |
| 20 | PPP1R12B | PPP1R12B StanfordSource, GeneCards | protein phosphatase 1, regulatory (inhibitor) subunit 12B | 10803 | -0.087 | -0.3638 | No |
| 21 | ARHGAP4 | ARHGAP4 StanfordSource, GeneCards | Rho GTPase activating protein 4 | 11534 | -0.112 | -0.3840 | No |
| 22 | ARPC1A | ARPC1A StanfordSource, GeneCards | actin related protein 2/3 complex, subunit 1A, 41kDa | 11578 | -0.114 | -0.3581 | No |
| 23 | DIAPH1 | DIAPH1 StanfordSource, GeneCards | diaphanous homolog 1 (Drosophila) | 12891 | -0.167 | -0.4031 | Yes |
| 24 | ARPC2 | ARPC2 StanfordSource, GeneCards | actin related protein 2/3 complex, subunit 2, 34kDa | 13151 | -0.179 | -0.3750 | Yes |
| 25 | SRC | SRC StanfordSource, GeneCards | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 13457 | -0.198 | -0.3452 | Yes |
| 26 | ARPC1B | ARPC1B StanfordSource, GeneCards | actin related protein 2/3 complex, subunit 1B, 41kDa | 13797 | -0.219 | -0.3122 | Yes |
| 27 | ACTR3 | ACTR3 StanfordSource, GeneCards | ARP3 actin-related protein 3 homolog (yeast) | 14874 | -0.366 | -0.2913 | Yes |
| 28 | CFL1 | CFL1 StanfordSource, GeneCards | cofilin 1 (non-muscle) | 14884 | -0.368 | -0.1987 | Yes |
| 29 | PIP5K1A | PIP5K1A StanfordSource, GeneCards | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 14938 | -0.391 | -0.1033 | Yes |
| 30 | PFN1 | PFN1 StanfordSource, GeneCards | profilin 1 | 14999 | -0.439 | 0.0037 | Yes |
