Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | DMT |
| GeneSet | C2.symbols.gmt#ucalpainPathway |
| Enrichment Score (ES) | -0.60767543 |
| Normalized Enrichment Score (NES) | -1.648966 |
| Nominal p-value | 0.026639344 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.69 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SRC | SRC StanfordSource, GeneCards | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 5526 | 0.070 | -0.3319 | No |
| 2 | PXN | PXN StanfordSource, GeneCards | paxillin | 5875 | 0.060 | -0.3244 | No |
| 3 | TLN1 | TLN1 StanfordSource, GeneCards | talin 1 | 6940 | 0.029 | -0.3802 | No |
| 4 | RAC1 | RAC1 StanfordSource, GeneCards | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 7596 | 0.011 | -0.4181 | No |
| 5 | PTK2 | PTK2 StanfordSource, GeneCards | PTK2 protein tyrosine kinase 2 | 9236 | -0.037 | -0.5083 | No |
| 6 | ACTN1 | ACTN1 StanfordSource, GeneCards | actinin, alpha 1 | 9893 | -0.057 | -0.5229 | No |
| 7 | ITGB3 | ITGB3 StanfordSource, GeneCards | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 10063 | -0.063 | -0.5022 | No |
| 8 | SPTAN1 | SPTAN1 StanfordSource, GeneCards | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 11650 | -0.119 | -0.5473 | Yes |
| 9 | VIL2 | VIL2 StanfordSource, GeneCards | villin 2 (ezrin) | 11689 | -0.120 | -0.4888 | Yes |
| 10 | ACTA1 | ACTA1 StanfordSource, GeneCards | actin, alpha 1, skeletal muscle | 12042 | -0.134 | -0.4440 | Yes |
| 11 | ACTN3 | ACTN3 StanfordSource, GeneCards | actinin, alpha 3 | 12385 | -0.151 | -0.3902 | Yes |
| 12 | ITGB1 | ITGB1 StanfordSource, GeneCards | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 12853 | -0.175 | -0.3325 | Yes |
| 13 | CAPN1 | CAPN1 StanfordSource, GeneCards | calpain 1, (mu/I) large subunit | 13166 | -0.194 | -0.2547 | Yes |
| 14 | ACTN2 | ACTN2 StanfordSource, GeneCards | actinin, alpha 2 | 14458 | -0.312 | -0.1821 | Yes |
| 15 | CAPNS1 | CAPNS1 StanfordSource, GeneCards | calpain, small subunit 1 | 14955 | -0.437 | 0.0066 | Yes |
