Dataset | Diabetes_collapsed.gct |
Phenotype | NGT |
GeneSet | C2.symbols.gmt#tollPathway |
Enrichment Score (ES) | 0.35742837 |
Normalized Enrichment Score (NES) | 1.2974914 |
Nominal p-value | 0.10706638 |
FDR q-value | 1.0 |
FWER p-Value | 0.998 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | SITPEC | SITPEC StanfordSource,  GeneCards | likely ortholog of mouse signaling intermediate in Toll pathway-evolutionarily conserved | 7 | 0.642 | 0.1572 | Yes |
2 | TLR7 | TLR7 StanfordSource,  GeneCards | toll-like receptor 7 | 871 | 0.284 | 0.1694 | Yes |
3 | TLR3 | TLR3 StanfordSource,  GeneCards | toll-like receptor 3 | 990 | 0.274 | 0.2287 | Yes |
4 | LY96 | LY96 StanfordSource,  GeneCards | lymphocyte antigen 96 | 1083 | 0.265 | 0.2877 | Yes |
5 | ELK1 | ELK1 StanfordSource,  GeneCards | ELK1, member of ETS oncogene family | 1168 | 0.259 | 0.3456 | Yes |
6 | IKBKB | IKBKB StanfordSource,  GeneCards | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 1787 | 0.216 | 0.3574 | Yes |
7 | TOLLIP | TOLLIP StanfordSource,  GeneCards | toll interacting protein | 3189 | 0.148 | 0.3006 | No |
8 | MAPK14 | MAPK14 StanfordSource,  GeneCards | mitogen-activated protein kinase 14 | 4214 | 0.110 | 0.2595 | No |
9 | NFKB1 | NFKB1 StanfordSource,  GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4741 | 0.094 | 0.2476 | No |
10 | MAP3K14 | MAP3K14 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase kinase 14 | 4842 | 0.091 | 0.2632 | No |
11 | MYD88 | MYD88 StanfordSource,  GeneCards | myeloid differentiation primary response gene (88) | 5475 | 0.071 | 0.2386 | No |
12 | MAP3K7IP2 | MAP3K7IP2 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase kinase 7 interacting protein 2 | 5671 | 0.066 | 0.2419 | No |
13 | CD14 | CD14 StanfordSource,  GeneCards | CD14 antigen | 6379 | 0.045 | 0.2058 | No |
14 | MAP2K3 | MAP2K3 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase 3 | 6407 | 0.044 | 0.2149 | No |
15 | MAP2K4 | MAP2K4 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase 4 | 6649 | 0.038 | 0.2081 | No |
16 | JUN | JUN StanfordSource,  GeneCards | v-jun sarcoma virus 17 oncogene homolog (avian) | 6697 | 0.036 | 0.2139 | No |
17 | TLR2 | TLR2 StanfordSource,  GeneCards | toll-like receptor 2 | 6884 | 0.031 | 0.2091 | No |
18 | MAPK8 | MAPK8 StanfordSource,  GeneCards | mitogen-activated protein kinase 8 | 7018 | 0.027 | 0.2070 | No |
19 | IKBKG | IKBKG StanfordSource,  GeneCards | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 7431 | 0.016 | 0.1834 | No |
20 | FOS | FOS StanfordSource,  GeneCards | v-fos FBJ murine osteosarcoma viral oncogene homolog | 7712 | 0.008 | 0.1667 | No |
21 | MAP3K7 | MAP3K7 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase kinase 7 | 7850 | 0.004 | 0.1585 | No |
22 | NFKBIA | NFKBIA StanfordSource,  GeneCards | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 8112 | -0.004 | 0.1420 | No |
23 | TLR6 | TLR6 StanfordSource,  GeneCards | toll-like receptor 6 | 8201 | -0.007 | 0.1378 | No |
24 | IRAK1 | IRAK1 StanfordSource,  GeneCards | interleukin-1 receptor-associated kinase 1 | 9640 | -0.049 | 0.0541 | No |
25 | CHUK | CHUK StanfordSource,  GeneCards | conserved helix-loop-helix ubiquitous kinase | 9958 | -0.059 | 0.0475 | No |
26 | MAP3K1 | MAP3K1 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase kinase 1 | 10474 | -0.077 | 0.0323 | No |
27 | TRAF6 | TRAF6 StanfordSource,  GeneCards | TNF receptor-associated factor 6 | 10587 | -0.081 | 0.0447 | No |
28 | PRKR | PRKR StanfordSource,  GeneCards | protein kinase, interferon-inducible double stranded RNA dependent | 10626 | -0.082 | 0.0624 | No |
29 | RELA | RELA StanfordSource,  GeneCards | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11053 | -0.097 | 0.0579 | No |
30 | TLR4 | TLR4 StanfordSource,  GeneCards | toll-like receptor 4 | 11999 | -0.133 | 0.0276 | No |
31 | MAP3K7IP1 | MAP3K7IP1 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase kinase 7 interacting protein 1 | 13086 | -0.189 | 0.0017 | No |
32 | MAP2K6 | MAP2K6 StanfordSource,  GeneCards | mitogen-activated protein kinase kinase 6 | 13919 | -0.249 | 0.0075 | No |
33 | PPARA | PPARA StanfordSource,  GeneCards | peroxisome proliferative activated receptor, alpha | 14193 | -0.277 | 0.0574 | No |