Dataset | Diabetes_collapsed.gct |
Phenotype | NGT |
GeneSet | C2.symbols.gmt#VOXPHOS |
Enrichment Score (ES) | 0.6227182 |
Normalized Enrichment Score (NES) | 1.9482467 |
Nominal p-value | 0.006772009 |
FDR q-value | 0.029732656 |
FWER p-Value | 0.058 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | NDUFA2 | NDUFA2 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 87 | 0.459 | 0.0224 | Yes |
2 | NDUFB2 | NDUFB2 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 102 | 0.446 | 0.0488 | Yes |
3 | COX7A1 | COX7A1 StanfordSource,  GeneCards | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 123 | 0.432 | 0.0740 | Yes |
4 | ATP5E | ATP5E StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 159 | 0.409 | 0.0968 | Yes |
5 | NDUFB6 | NDUFB6 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 165 | 0.406 | 0.1214 | Yes |
6 | ATP5O | ATP5O StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 217 | 0.392 | 0.1421 | Yes |
7 | NDUFB8 | NDUFB8 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 239 | 0.387 | 0.1645 | Yes |
8 | NDUFB1 | NDUFB1 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 244 | 0.385 | 0.1878 | Yes |
9 | QP-C | QP-C StanfordSource,  GeneCards | low molecular mass ubiquinone-binding protein (9.5kD) | 270 | 0.377 | 0.2093 | Yes |
10 | NDUFS5 | NDUFS5 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 291 | 0.372 | 0.2309 | Yes |
11 | COX7C | COX7C StanfordSource,  GeneCards | cytochrome c oxidase subunit VIIc | 363 | 0.353 | 0.2479 | Yes |
12 | COX7B | COX7B StanfordSource,  GeneCards | cytochrome c oxidase subunit VIIb | 366 | 0.353 | 0.2694 | Yes |
13 | UQCR | UQCR StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase (6.4kD) subunit | 376 | 0.350 | 0.2903 | Yes |
14 | ATP5L | ATP5L StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g | 391 | 0.348 | 0.3108 | Yes |
15 | ATP5I | ATP5I StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e | 414 | 0.342 | 0.3303 | Yes |
16 | NDUFA7 | NDUFA7 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 484 | 0.330 | 0.3460 | Yes |
17 | COX7A2 | COX7A2 StanfordSource,  GeneCards | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 557 | 0.317 | 0.3607 | Yes |
18 | NDUFA10 | NDUFA10 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 817 | 0.289 | 0.3611 | Yes |
19 | NDUFS6 | NDUFS6 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 919 | 0.280 | 0.3716 | Yes |
20 | NDUFS8 | NDUFS8 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 940 | 0.278 | 0.3873 | Yes |
21 | UQCRB | UQCRB StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase binding protein | 1022 | 0.270 | 0.3985 | Yes |
22 | COX6C | COX6C StanfordSource,  GeneCards | cytochrome c oxidase subunit VIc | 1115 | 0.263 | 0.4085 | Yes |
23 | NDUFC1 | NDUFC1 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 1120 | 0.262 | 0.4244 | Yes |
24 | NDUFA6 | NDUFA6 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 1126 | 0.262 | 0.4401 | Yes |
25 | COX7A2L | COX7A2L StanfordSource,  GeneCards | cytochrome c oxidase subunit VIIa polypeptide 2 like | 1186 | 0.257 | 0.4520 | Yes |
26 | ATP5J2 | ATP5J2 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 | 1206 | 0.255 | 0.4664 | Yes |
27 | NDUFA3 | NDUFA3 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 1209 | 0.255 | 0.4819 | Yes |
28 | HSPC051 | HSPC051 StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase complex (7.2 kD) | 1233 | 0.254 | 0.4960 | Yes |
29 | ATP5H | ATP5H StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 1275 | 0.250 | 0.5086 | Yes |
30 | NDUFB5 | NDUFB5 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 1372 | 0.244 | 0.5172 | Yes |
31 | COX6A1 | COX6A1 StanfordSource,  GeneCards | cytochrome c oxidase subunit VIa polypeptide 1 | 1520 | 0.233 | 0.5217 | Yes |
32 | NGFRAP1 | NGFRAP1 StanfordSource,  GeneCards | nerve growth factor receptor (TNFRSF16) associated protein 1 | 1528 | 0.233 | 0.5355 | Yes |
33 | NDUFAB1 | NDUFAB1 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 1572 | 0.229 | 0.5467 | Yes |
34 | SDHC | SDHC StanfordSource,  GeneCards | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 1696 | 0.220 | 0.5521 | Yes |
35 | CYC1 | CYC1 StanfordSource,  GeneCards | cytochrome c-1 | 1751 | 0.217 | 0.5618 | Yes |
36 | ATP5F1 | ATP5F1 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1 | 1770 | 0.216 | 0.5739 | Yes |
37 | NDUFA8 | NDUFA8 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 1780 | 0.216 | 0.5866 | Yes |
38 | COX4I1 | COX4I1 StanfordSource,  GeneCards | cytochrome c oxidase subunit IV isoform 1 | 2139 | 0.196 | 0.5747 | Yes |
39 | NDUFA4 | NDUFA4 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 2181 | 0.194 | 0.5838 | Yes |
40 | SDHB | SDHB StanfordSource,  GeneCards | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2222 | 0.192 | 0.5930 | Yes |
41 | NDUFS7 | NDUFS7 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2255 | 0.191 | 0.6025 | Yes |
42 | COX11 | COX11 StanfordSource,  GeneCards | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | 2317 | 0.188 | 0.6100 | Yes |
43 | PET112L | PET112L StanfordSource,  GeneCards | PET112-like (yeast) | 2329 | 0.187 | 0.6207 | Yes |
44 | ATP5D | ATP5D StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 2524 | 0.178 | 0.6187 | Yes |
45 | UQCRH | UQCRH StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase hinge protein | 2668 | 0.170 | 0.6196 | Yes |
46 | NDUFS4 | NDUFS4 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2775 | 0.166 | 0.6227 | Yes |
47 | COX5B | COX5B StanfordSource,  GeneCards | cytochrome c oxidase subunit Vb | 3139 | 0.150 | 0.6077 | No |
48 | NDUFB7 | NDUFB7 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 3295 | 0.144 | 0.6062 | No |
49 | NDUFB3 | NDUFB3 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 3404 | 0.141 | 0.6077 | No |
50 | UQCRFS1 | UQCRFS1 StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 3411 | 0.141 | 0.6159 | No |
51 | GRIM19 | GRIM19 StanfordSource,  GeneCards | cell death-regulatory protein GRIM19 | 4191 | 0.111 | 0.5707 | No |
52 | ATP5G3 | ATP5G3 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 | 4232 | 0.110 | 0.5748 | No |
53 | SURF1 | SURF1 StanfordSource,  GeneCards | surfeit 1 | 4276 | 0.108 | 0.5786 | No |
54 | ATP5G1 | ATP5G1 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 | 4435 | 0.103 | 0.5744 | No |
55 | ATP5J | ATP5J StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 4519 | 0.101 | 0.5750 | No |
56 | COX10 | COX10 StanfordSource,  GeneCards | COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) | 4549 | 0.100 | 0.5792 | No |
57 | CYCS | CYCS StanfordSource,  GeneCards | cytochrome c, somatic | 4647 | 0.096 | 0.5787 | No |
58 | ATP5C1 | ATP5C1 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 5016 | 0.086 | 0.5594 | No |
59 | COX5A | COX5A StanfordSource,  GeneCards | cytochrome c oxidase subunit Va | 5029 | 0.086 | 0.5638 | No |
60 | CYB5 | CYB5 StanfordSource,  GeneCards | cytochrome b-5 | 5532 | 0.070 | 0.5346 | No |
61 | SURF2 | SURF2 StanfordSource,  GeneCards | surfeit 2 | 5768 | 0.063 | 0.5228 | No |
62 | COX15 | COX15 StanfordSource,  GeneCards | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 5785 | 0.063 | 0.5256 | No |
63 | CNOT7 | CNOT7 StanfordSource,  GeneCards | CCR4-NOT transcription complex, subunit 7 | 5896 | 0.059 | 0.5219 | No |
64 | NDUFS2 | NDUFS2 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 6190 | 0.050 | 0.5054 | No |
65 | NDUFS3 | NDUFS3 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 6363 | 0.045 | 0.4967 | No |
66 | NDUFA5 | NDUFA5 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 6374 | 0.045 | 0.4988 | No |
67 | NDUFA9 | NDUFA9 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6922 | 0.030 | 0.4641 | No |
68 | MBD3 | MBD3 StanfordSource,  GeneCards | methyl-CpG binding domain protein 3 | 6974 | 0.029 | 0.4624 | No |
69 | SDHD | SDHD StanfordSource,  GeneCards | succinate dehydrogenase complex, subunit D, integral membrane protein | 7356 | 0.018 | 0.4381 | No |
70 | UQCRC2 | UQCRC2 StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase core protein II | 7403 | 0.016 | 0.4360 | No |
71 | NDUFC2 | NDUFC2 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 8421 | -0.013 | 0.3689 | No |
72 | NDUFS1 | NDUFS1 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8811 | -0.024 | 0.3443 | No |
73 | ATP5G2 | ATP5G2 StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 | 8920 | -0.027 | 0.3388 | No |
74 | ATP5B | ATP5B StanfordSource,  GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 9051 | -0.031 | 0.3320 | No |
75 | COX6A2 | COX6A2 StanfordSource,  GeneCards | cytochrome c oxidase subunit VIa polypeptide 2 | 10177 | -0.067 | 0.2610 | No |
76 | NDUFB4 | NDUFB4 StanfordSource,  GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 10558 | -0.080 | 0.2406 | No |
77 | BCL2L1 | BCL2L1 StanfordSource,  GeneCards | BCL2-like 1 | 10708 | -0.085 | 0.2358 | No |
78 | ZNF183 | ZNF183 StanfordSource,  GeneCards | zinc finger protein 183 (RING finger, C3HC4 type) | 10835 | -0.090 | 0.2330 | No |
79 | CKAP1 | CKAP1 StanfordSource,  GeneCards | cytoskeleton associated protein 1 | 10902 | -0.092 | 0.2342 | No |
80 | BCS1L | BCS1L StanfordSource,  GeneCards | BCS1-like (yeast) | 11531 | -0.114 | 0.1993 | No |
81 | SDHA | SDHA StanfordSource,  GeneCards | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 12501 | -0.156 | 0.1442 | No |
82 | UQCRC1 | UQCRC1 StanfordSource,  GeneCards | ubiquinol-cytochrome c reductase core protein I | 12601 | -0.161 | 0.1475 | No |
83 | LOC56901 | LOC56901 StanfordSource,  GeneCards | NADH:ubiquinone oxidoreductase MLRQ subunit homolog | 14104 | -0.266 | 0.0635 | No |