Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | DMT |
| GeneSet | C2.symbols.gmt#ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway |
| Enrichment Score (ES) | -0.3685537 |
| Normalized Enrichment Score (NES) | -1.3902766 |
| Nominal p-value | 0.058139537 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.989 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ITGA9 | ITGA9 StanfordSource, GeneCards | integrin, alpha 9 | 1279 | 0.250 | -0.0381 | No |
| 2 | ETFA | ETFA StanfordSource, GeneCards | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 1645 | 0.224 | -0.0202 | No |
| 3 | ITPKA | ITPKA StanfordSource, GeneCards | inositol 1,4,5-trisphosphate 3-kinase A | 1674 | 0.222 | 0.0197 | No |
| 4 | PIK3CD | PIK3CD StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, delta polypeptide | 1993 | 0.204 | 0.0369 | No |
| 5 | RPS4X | RPS4X StanfordSource, GeneCards | ribosomal protein S4, X-linked | 2078 | 0.198 | 0.0686 | No |
| 6 | GCA | GCA StanfordSource, GeneCards | grancalcin, EF-hand calcium binding protein | 2710 | 0.168 | 0.0583 | No |
| 7 | VASP | VASP StanfordSource, GeneCards | vasodilator-stimulated phosphoprotein | 3000 | 0.157 | 0.0686 | No |
| 8 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 3210 | 0.148 | 0.0825 | No |
| 9 | ANGPTL2 | ANGPTL2 StanfordSource, GeneCards | angiopoietin-like 2 | 4156 | 0.113 | 0.0409 | No |
| 10 | PIK3C2G | PIK3C2G StanfordSource, GeneCards | phosphoinositide-3-kinase, class 2, gamma polypeptide | 4265 | 0.108 | 0.0541 | No |
| 11 | ACTR2 | ACTR2 StanfordSource, GeneCards | ARP2 actin-related protein 2 homolog (yeast) | 4372 | 0.105 | 0.0669 | No |
| 12 | PSME1 | PSME1 StanfordSource, GeneCards | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 4907 | 0.089 | 0.0481 | No |
| 13 | PIK3R1 | PIK3R1 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 8274 | -0.009 | -0.1743 | No |
| 14 | ACTR3 | ACTR3 StanfordSource, GeneCards | ARP3 actin-related protein 3 homolog (yeast) | 9565 | -0.047 | -0.2514 | No |
| 15 | ITPR1 | ITPR1 StanfordSource, GeneCards | inositol 1,4,5-triphosphate receptor, type 1 | 9870 | -0.056 | -0.2610 | No |
| 16 | PDE3B | PDE3B StanfordSource, GeneCards | phosphodiesterase 3B, cGMP-inhibited | 9983 | -0.060 | -0.2572 | No |
| 17 | PI3 | PI3 StanfordSource, GeneCards | protease inhibitor 3, skin-derived (SKALP) | 10681 | -0.084 | -0.2877 | No |
| 18 | ITPR2 | ITPR2 StanfordSource, GeneCards | inositol 1,4,5-triphosphate receptor, type 2 | 10780 | -0.088 | -0.2777 | No |
| 19 | PIK3CA | PIK3CA StanfordSource, GeneCards | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 11164 | -0.101 | -0.2842 | No |
| 20 | ITPR3 | ITPR3 StanfordSource, GeneCards | inositol 1,4,5-triphosphate receptor, type 3 | 11343 | -0.107 | -0.2758 | No |
| 21 | ITPKB | ITPKB StanfordSource, GeneCards | inositol 1,4,5-trisphosphate 3-kinase B | 11386 | -0.109 | -0.2581 | No |
| 22 | BF | BF StanfordSource, GeneCards | B-factor, properdin | 13046 | -0.187 | -0.3334 | Yes |
| 23 | SGCB | SGCB StanfordSource, GeneCards | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 13139 | -0.193 | -0.3032 | Yes |
| 24 | MAPK1 | MAPK1 StanfordSource, GeneCards | mitogen-activated protein kinase 1 | 13258 | -0.200 | -0.2734 | Yes |
| 25 | MAP2K1 | MAP2K1 StanfordSource, GeneCards | mitogen-activated protein kinase kinase 1 | 13396 | -0.210 | -0.2430 | Yes |
| 26 | MAPK3 | MAPK3 StanfordSource, GeneCards | mitogen-activated protein kinase 3 | 13499 | -0.216 | -0.2092 | Yes |
| 27 | NR1I3 | NR1I3 StanfordSource, GeneCards | nuclear receptor subfamily 1, group I, member 3 | 14053 | -0.261 | -0.1968 | Yes |
| 28 | PAK1 | PAK1 StanfordSource, GeneCards | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 14220 | -0.281 | -0.1549 | Yes |
| 29 | PDE3A | PDE3A StanfordSource, GeneCards | phosphodiesterase 3A, cGMP-inhibited | 14517 | -0.322 | -0.1140 | Yes |
| 30 | DAG1 | DAG1 StanfordSource, GeneCards | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 14785 | -0.374 | -0.0613 | Yes |
| 31 | DGKA | DGKA StanfordSource, GeneCards | diacylglycerol kinase, alpha 80kDa | 14929 | -0.421 | 0.0084 | Yes |
