Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | NGT |
| GeneSet | C2.symbols.gmt#Electron_Transport_Chain |
| Enrichment Score (ES) | 0.614574 |
| Normalized Enrichment Score (NES) | 1.8894085 |
| Nominal p-value | 0.018058691 |
| FDR q-value | 0.04393733 |
| FWER p-Value | 0.122 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NDUFA2 | NDUFA2 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 87 | 0.459 | 0.0218 | Yes |
| 2 | NDUFB2 | NDUFB2 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | 102 | 0.446 | 0.0477 | Yes |
| 3 | COX7A1 | COX7A1 StanfordSource, GeneCards | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 123 | 0.432 | 0.0723 | Yes |
| 4 | ATP5E | ATP5E StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 159 | 0.409 | 0.0946 | Yes |
| 5 | NDUFB6 | NDUFB6 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 165 | 0.406 | 0.1186 | Yes |
| 6 | ATP5O | ATP5O StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 217 | 0.392 | 0.1388 | Yes |
| 7 | NDUFB8 | NDUFB8 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 239 | 0.387 | 0.1607 | Yes |
| 8 | NDUFB1 | NDUFB1 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 244 | 0.385 | 0.1836 | Yes |
| 9 | QP-C | QP-C StanfordSource, GeneCards | low molecular mass ubiquinone-binding protein (9.5kD) | 270 | 0.377 | 0.2046 | Yes |
| 10 | NDUFS5 | NDUFS5 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 291 | 0.372 | 0.2257 | Yes |
| 11 | COX7C | COX7C StanfordSource, GeneCards | cytochrome c oxidase subunit VIIc | 363 | 0.353 | 0.2422 | Yes |
| 12 | COX7B | COX7B StanfordSource, GeneCards | cytochrome c oxidase subunit VIIb | 366 | 0.353 | 0.2633 | Yes |
| 13 | UQCR | UQCR StanfordSource, GeneCards | ubiquinol-cytochrome c reductase (6.4kD) subunit | 376 | 0.350 | 0.2838 | Yes |
| 14 | ATP5L | ATP5L StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g | 391 | 0.348 | 0.3037 | Yes |
| 15 | ATP5I | ATP5I StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e | 414 | 0.342 | 0.3229 | Yes |
| 16 | ATP5S | ATP5S StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) | 467 | 0.332 | 0.3394 | Yes |
| 17 | NDUFA7 | NDUFA7 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 484 | 0.330 | 0.3582 | Yes |
| 18 | COX7A2 | COX7A2 StanfordSource, GeneCards | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 557 | 0.317 | 0.3725 | Yes |
| 19 | NDUFA10 | NDUFA10 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 817 | 0.289 | 0.3726 | Yes |
| 20 | NDUFS6 | NDUFS6 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 919 | 0.280 | 0.3827 | Yes |
| 21 | NDUFS8 | NDUFS8 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 940 | 0.278 | 0.3980 | Yes |
| 22 | SLC25A5 | SLC25A5 StanfordSource, GeneCards | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 960 | 0.276 | 0.4134 | Yes |
| 23 | UQCRB | UQCRB StanfordSource, GeneCards | ubiquinol-cytochrome c reductase binding protein | 1022 | 0.270 | 0.4256 | Yes |
| 24 | COX6C | COX6C StanfordSource, GeneCards | cytochrome c oxidase subunit VIc | 1115 | 0.263 | 0.4352 | Yes |
| 25 | NDUFC1 | NDUFC1 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 1120 | 0.262 | 0.4507 | Yes |
| 26 | NDUFA6 | NDUFA6 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 1126 | 0.262 | 0.4662 | Yes |
| 27 | COX7A2L | COX7A2L StanfordSource, GeneCards | cytochrome c oxidase subunit VIIa polypeptide 2 like | 1186 | 0.257 | 0.4777 | Yes |
| 28 | ATP5J2 | ATP5J2 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f, isoform 2 | 1206 | 0.255 | 0.4918 | Yes |
| 29 | NDUFA3 | NDUFA3 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 1209 | 0.255 | 0.5070 | Yes |
| 30 | HSPC051 | HSPC051 StanfordSource, GeneCards | ubiquinol-cytochrome c reductase complex (7.2 kD) | 1233 | 0.254 | 0.5207 | Yes |
| 31 | ATP5H | ATP5H StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 1275 | 0.250 | 0.5330 | Yes |
| 32 | NDUFB5 | NDUFB5 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 1372 | 0.244 | 0.5413 | Yes |
| 33 | COX6A1 | COX6A1 StanfordSource, GeneCards | cytochrome c oxidase subunit VIa polypeptide 1 | 1520 | 0.233 | 0.5455 | Yes |
| 34 | NDUFAB1 | NDUFAB1 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 1572 | 0.229 | 0.5559 | Yes |
| 35 | SDHC | SDHC StanfordSource, GeneCards | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 1696 | 0.220 | 0.5609 | Yes |
| 36 | ATP5F1 | ATP5F1 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1 | 1770 | 0.216 | 0.5690 | Yes |
| 37 | NDUFA8 | NDUFA8 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 1780 | 0.216 | 0.5814 | Yes |
| 38 | COX4I1 | COX4I1 StanfordSource, GeneCards | cytochrome c oxidase subunit IV isoform 1 | 2139 | 0.196 | 0.5693 | Yes |
| 39 | NDUFA4 | NDUFA4 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 2181 | 0.194 | 0.5782 | Yes |
| 40 | SDHB | SDHB StanfordSource, GeneCards | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 2222 | 0.192 | 0.5871 | Yes |
| 41 | NDUFS7 | NDUFS7 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2255 | 0.191 | 0.5964 | Yes |
| 42 | COX11 | COX11 StanfordSource, GeneCards | COX11 homolog, cytochrome c oxidase assembly protein (yeast) | 2317 | 0.188 | 0.6036 | Yes |
| 43 | ATP5D | ATP5D StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 2524 | 0.178 | 0.6005 | Yes |
| 44 | ATPIF1 | ATPIF1 StanfordSource, GeneCards | ATPase inhibitory factor 1 | 2636 | 0.173 | 0.6035 | Yes |
| 45 | UQCRH | UQCRH StanfordSource, GeneCards | ubiquinol-cytochrome c reductase hinge protein | 2668 | 0.170 | 0.6117 | Yes |
| 46 | NDUFS4 | NDUFS4 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2775 | 0.166 | 0.6146 | Yes |
| 47 | COX5B | COX5B StanfordSource, GeneCards | cytochrome c oxidase subunit Vb | 3139 | 0.150 | 0.5994 | No |
| 48 | NDUFB7 | NDUFB7 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 3295 | 0.144 | 0.5977 | No |
| 49 | NDUFB3 | NDUFB3 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 3404 | 0.141 | 0.5990 | No |
| 50 | UQCRFS1 | UQCRFS1 StanfordSource, GeneCards | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 3411 | 0.141 | 0.6070 | No |
| 51 | SLC25A14 | SLC25A14 StanfordSource, GeneCards | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 3652 | 0.130 | 0.5989 | No |
| 52 | NDUFV2 | NDUFV2 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 3775 | 0.125 | 0.5983 | No |
| 53 | SLC25A6 | SLC25A6 StanfordSource, GeneCards | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 4168 | 0.112 | 0.5788 | No |
| 54 | ATP5G3 | ATP5G3 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 | 4232 | 0.110 | 0.5812 | No |
| 55 | SURF1 | SURF1 StanfordSource, GeneCards | surfeit 1 | 4276 | 0.108 | 0.5848 | No |
| 56 | NDUFV1 | NDUFV1 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 4325 | 0.107 | 0.5880 | No |
| 57 | AFG3L2 | AFG3L2 StanfordSource, GeneCards | AFG3 ATPase family gene 3-like 2 (yeast) | 4338 | 0.107 | 0.5937 | No |
| 58 | ATP5G1 | ATP5G1 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 | 4435 | 0.103 | 0.5935 | No |
| 59 | ATP5J | ATP5J StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 4519 | 0.101 | 0.5940 | No |
| 60 | CYCS | CYCS StanfordSource, GeneCards | cytochrome c, somatic | 4647 | 0.096 | 0.5913 | No |
| 61 | ATP5C1 | ATP5C1 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 5016 | 0.086 | 0.5719 | No |
| 62 | COX5A | COX5A StanfordSource, GeneCards | cytochrome c oxidase subunit Va | 5029 | 0.086 | 0.5762 | No |
| 63 | COX15 | COX15 StanfordSource, GeneCards | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 5785 | 0.063 | 0.5296 | No |
| 64 | NDUFS2 | NDUFS2 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 6190 | 0.050 | 0.5056 | No |
| 65 | NDUFS3 | NDUFS3 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 6363 | 0.045 | 0.4969 | No |
| 66 | NDUFA5 | NDUFA5 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 6374 | 0.045 | 0.4989 | No |
| 67 | NDUFA9 | NDUFA9 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6922 | 0.030 | 0.4642 | No |
| 68 | SDHD | SDHD StanfordSource, GeneCards | succinate dehydrogenase complex, subunit D, integral membrane protein | 7356 | 0.018 | 0.4363 | No |
| 69 | UQCRC2 | UQCRC2 StanfordSource, GeneCards | ubiquinol-cytochrome c reductase core protein II | 7403 | 0.016 | 0.4342 | No |
| 70 | TBDN100 | TBDN100 StanfordSource, GeneCards | transcriptional coactivator tubedown-100 | 7892 | 0.003 | 0.4018 | No |
| 71 | NDUFC2 | NDUFC2 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 8421 | -0.013 | 0.3673 | No |
| 72 | POPDC2 | POPDC2 StanfordSource, GeneCards | popeye domain containing 2 | 8557 | -0.016 | 0.3592 | No |
| 73 | NDUFS1 | NDUFS1 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8811 | -0.024 | 0.3438 | No |
| 74 | UCP1 | UCP1 StanfordSource, GeneCards | uncoupling protein 1 (mitochondrial, proton carrier) | 8824 | -0.024 | 0.3444 | No |
| 75 | ATP5G2 | ATP5G2 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 | 8920 | -0.027 | 0.3397 | No |
| 76 | ATP5B | ATP5B StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 9051 | -0.031 | 0.3329 | No |
| 77 | SLC25A4 | SLC25A4 StanfordSource, GeneCards | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 9606 | -0.048 | 0.2987 | No |
| 78 | UCP3 | UCP3 StanfordSource, GeneCards | uncoupling protein 3 (mitochondrial, proton carrier) | 9668 | -0.050 | 0.2977 | No |
| 79 | COX6A2 | COX6A2 StanfordSource, GeneCards | cytochrome c oxidase subunit VIa polypeptide 2 | 10177 | -0.067 | 0.2678 | No |
| 80 | NDUFB4 | NDUFB4 StanfordSource, GeneCards | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 10558 | -0.080 | 0.2472 | No |
| 81 | ZNF183 | ZNF183 StanfordSource, GeneCards | zinc finger protein 183 (RING finger, C3HC4 type) | 10835 | -0.090 | 0.2342 | No |
| 82 | UCP2 | UCP2 StanfordSource, GeneCards | uncoupling protein 2 (mitochondrial, proton carrier) | 12284 | -0.147 | 0.1463 | No |
| 83 | SDHA | SDHA StanfordSource, GeneCards | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 12501 | -0.156 | 0.1412 | No |
| 84 | UQCRC1 | UQCRC1 StanfordSource, GeneCards | ubiquinol-cytochrome c reductase core protein I | 12601 | -0.161 | 0.1443 | No |
| 85 | ATP5A1 | ATP5A1 StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle | 14538 | -0.325 | 0.0345 | No |
