# gene_set_details

systematic_name: M13601
exact_source: GO:0042481
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042481
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. [GOC:jl]


systematic_name: M23539
exact_source: GO:0042482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. [GOC:jl]


systematic_name: M16662
exact_source: GO:0042487
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042487
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. [GOC:jl, GOC:mtg_sensu, PMID:15355794]


systematic_name: M14332
exact_source: GO:0042490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. [CL:0000199, GOC:jl]


systematic_name: M23542
exact_source: GO:0042492
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042492
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex. [CL:0000798, GOC:jl]


systematic_name: M23543
exact_source: GO:0042501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:10918594]


systematic_name: M23544
exact_source: GO:0042531
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042531
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:11426647]


systematic_name: M23545
exact_source: GO:0042532
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042532
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:11426647]


systematic_name: M14283
exact_source: GO:0042537
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042537
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives. [GOC:jl]


systematic_name: M23549
exact_source: GO:0042538
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042538
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. [GOC:jl]


systematic_name: M23550
exact_source: GO:0042541
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042541
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. [GOC:jl]


systematic_name: M16710
exact_source: GO:0042542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. [GOC:jl]


systematic_name: M10809
exact_source: GO:0042551
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042551
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. [GOC:dph, GOC:jl]


systematic_name: M14662
exact_source: GO:0042554
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042554
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways. [GOC:jl, PMID:12359750]


systematic_name: M12704
exact_source: GO:0042558
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042558
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. [GOC:jl, ISBN:0198506732]


systematic_name: M12255
exact_source: GO:0042559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. [GOC:jl, ISBN:0198506732]


systematic_name: M11434
exact_source: GO:0042572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A. [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html, PMID:1924551]


systematic_name: M13918
exact_source: GO:0042573
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042573
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A. [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html]


systematic_name: M13880
exact_source: GO:0042574
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042574
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A. [ISBN:0198506732]


systematic_name: M13990
exact_source: GO:0042590
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042590
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. [GOC:add, ISBN:0781735149, PMID:15771591]


systematic_name: M17351
exact_source: GO:0042592
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042592
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of an internal steady state. [GOC:jl, ISBN:0395825172]


systematic_name: M16522
exact_source: GO:0042594
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042594
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment. [GOC:go_curators]


systematic_name: M11508
exact_source: GO:0042634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. [GOC:go_curators, PMID:12230507]


systematic_name: M42784
exact_source: GO:0042640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair. [PMID:12230507]


systematic_name: M23553
exact_source: GO:0042661
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042661
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of mesoderm cell fate specification. [GOC:go_curators]


systematic_name: M23554
exact_source: GO:0042670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. [GOC:go_curators]


systematic_name: M17152
exact_source: GO:0042692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. [CL:0000187, GOC:go_curators]


systematic_name: M14615
exact_source: GO:0042693
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042693
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the cellular identity of muscle cells is acquired and determined. [CL:0000187, GOC:go_curators]


systematic_name: M5523
exact_source: GO:0042698
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042698
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. [ISBN:0721662544]


systematic_name: M23555
exact_source: GO:0042713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. [GOC:jl, http://www.cogsci.princeton.edu/~wn/]


systematic_name: M23556
exact_source: GO:0042723
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042723
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it. [GOC:jl]


systematic_name: M29172
exact_source: GO:0042726
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042726
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position. [GOC:jl, GOC:mah]


systematic_name: M15446
exact_source: GO:0042730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin. [GOC:jl, PMID:15842654]


systematic_name: M10708
exact_source: GO:0042733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe. [GOC:bf, GOC:jl, UBERON:0002544]


systematic_name: M15579
exact_source: GO:0042742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. [GOC:jl]


systematic_name: M15190
exact_source: GO:0042743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. [GOC:jl, PMID:21734470]


systematic_name: M10838
exact_source: GO:0042744
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042744
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). [GOC:jl]


systematic_name: M23557
exact_source: GO:0042745
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042745
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. [GOC:jl, http://www.sleepquest.com]


systematic_name: M23559
exact_source: GO:0042748
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042748
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. [GOC:jl, http://www.sleepquest.com]


systematic_name: M12080
exact_source: GO:0042752
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042752
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. [GOC:dph, GOC:jl, GOC:tb]


systematic_name: M13729
exact_source: GO:0042753
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042753
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. [GOC:go_curators]


systematic_name: M14104
exact_source: GO:0042754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. [GOC:go_curators]


systematic_name: M12447
exact_source: GO:0042755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. [GOC:jl, GOC:pr, PMID:19361967]


systematic_name: M23560
exact_source: GO:0042756
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042756
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific behavior of an organism relating to the intake of liquids, especially water. [GOC:curators, GOC:pr]


systematic_name: M23561
exact_source: GO:0042758
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042758
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [PMID:20043225]


systematic_name: M23562
exact_source: GO:0042759
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042759
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a long-chain fatty acid. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [PMID:18390550]


systematic_name: M23563
exact_source: GO:0042760
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042760
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. [PMID:7744868]


systematic_name: M48442
exact_source: GO:0042761
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042761
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. [PMID:7744868]


systematic_name: M29173
exact_source: GO:0042762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. [GOC:go_curators]


systematic_name: M10278
exact_source: GO:0042771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. [GOC:go_curators, GOC:mtg_apoptosis]


systematic_name: M16861
exact_source: GO:0042772
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042772
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription. [GOC:go_curators]


systematic_name: M23564
exact_source: GO:0042773
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042773
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP. [ISBN:0716731363]


systematic_name: M23565
exact_source: GO:0042780
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042780
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA. [GOC:go_curators]


systematic_name: M23567
exact_source: GO:0042790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I. [GOC:jl, GOC:txnOH, ISBN:0321000382]


systematic_name: M29174
exact_source: GO:0042791
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042791
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter. [GOC:jl, GOC:txnOH, ISBN:0321000382, PMID:12381659]


systematic_name: M42786
exact_source: GO:0042795
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042795
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter. [GOC:jl, ISBN:0321000382]


systematic_name: M23568
exact_source: GO:0042796
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042796
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter. [GOC:jl, ISBN:0321000382]


systematic_name: M29175
exact_source: GO:0042816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html]


systematic_name: M42787
exact_source: GO:0042886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl, ISBN:0198506732]


systematic_name: M23570
exact_source: GO:0042908
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042908
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc]


systematic_name: M48443
exact_source: GO:0042918
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042918
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical. [PMID:31802112]


systematic_name: M48444
exact_source: GO:0042939
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042939
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M23571
exact_source: GO:0042940
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042940
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl, GOC:jsg, GOC:mah]


systematic_name: M23572
exact_source: GO:0042976
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042976
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. [GOC:jl, PMID:12479803]


systematic_name: M14901
exact_source: GO:0042982
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042982
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. [GOC:go_curators]


systematic_name: M23573
exact_source: GO:0042983
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042983
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. [GOC:go_curators]


systematic_name: M23574
exact_source: GO:0042985
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042985
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta. [GOC:go_curators]


systematic_name: M23575
exact_source: GO:0042987
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042987
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease. [GOC:go_curators]


systematic_name: M23576
exact_source: GO:0042989
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042989
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers. [GOC:go_curators]


systematic_name: M13757
exact_source: GO:0042994
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042994
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. [GOC:jl]


systematic_name: M23577
exact_source: GO:0042996
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042996
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. [GOC:jl]


systematic_name: M42788
exact_source: GO:0042998
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042998
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. [GOC:jl]


systematic_name: M13776
exact_source: GO:0043001
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043001
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. [ISBN:0716731363]


systematic_name: M16621
exact_source: GO:0043011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. [CL:0000782, GOC:jl]


systematic_name: M10932
exact_source: GO:0043029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M23579
exact_source: GO:0043031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. [GOC:jl]


systematic_name: M10357
exact_source: GO:0043038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. [GOC:jl]


systematic_name: M23580
exact_source: GO:0043043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. [GOC:dph, GOC:jl]


systematic_name: M45868
exact_source: GO:0043045
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043045
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation. [GOC:go_curators, PMID:12138111, PMID:22868271]


systematic_name: M46792
exact_source: GO:0043067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. [GOC:jl]


systematic_name: M46793
exact_source: GO:0043068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. [GOC:jl]


systematic_name: M46794
exact_source: GO:0043069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. [GOC:jl]


systematic_name: M23581
exact_source: GO:0043084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. [GOC:jl, Wikipedia:Penile_erection]


systematic_name: M12283
exact_source: GO:0043085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]


systematic_name: M16622
exact_source: GO:0043094
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043094
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells. [GOC:mlg]


systematic_name: M11752
exact_source: GO:0043101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis. [GOC:jl]


systematic_name: M23582
exact_source: GO:0043102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces an amino acid from derivatives of it, without de novo synthesis. [GOC:jl]


systematic_name: M13654
exact_source: GO:0043112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:jl]


systematic_name: M16895
exact_source: GO:0043113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. [GOC:bf, GOC:jl, GOC:pr, PMID:19747931, PMID:21453460]


systematic_name: M15704
exact_source: GO:0043123
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043123
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl]


systematic_name: M14214
exact_source: GO:0043124
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043124
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade. [GOC:jl]


systematic_name: M45869
exact_source: GO:0043129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid. [PMID:23708874, PMID:9751757]


systematic_name: M45147
exact_source: GO:0043132
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043132
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:jl]


systematic_name: M42789
exact_source: GO:0043144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea). [GOC:go_curators, GOC:krc, PMID:12773397]


systematic_name: M34168
exact_source: GO:0043149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity. [GOC:go_curators, GOC:mah, PMID:16651381]


systematic_name: M46795
exact_source: GO:0043154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process. [GOC:jl, GOC:mtg_apoptosis]


systematic_name: M48445
exact_source: GO:0043161
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043161
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. [GOC:go_curators]


systematic_name: M15937
exact_source: GO:0043162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. [GOC:jl, PMID:11511343]


systematic_name: M16063
exact_source: GO:0043171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. [GOC:jl]


systematic_name: M16619
exact_source: GO:0043173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis. [GOC:jl]


systematic_name: M13655
exact_source: GO:0043174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis. [GOC:jl]


systematic_name: M23588
exact_source: GO:0043201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus. [GOC:mlg]


systematic_name: M15536
exact_source: GO:0043217
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043217
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath. [GOC:dgh]


systematic_name: M14373
exact_source: GO:0043242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. [GOC:jl]


systematic_name: M11530
exact_source: GO:0043243
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043243
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. [GOC:jl]


systematic_name: M15714
exact_source: GO:0043244
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043244
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. [GOC:jl]


systematic_name: M23589
exact_source: GO:0043247
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043247
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that occur in response to the presence of critically short or damaged telomeres. [GOC:BHF, GOC:BHF_telomere, GOC:jbu, PMID:15279784]


systematic_name: M11207
exact_source: GO:0043248
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043248
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a mature, active proteasome complex. [GOC:go_curators, PMID:10872471]


systematic_name: M13459
exact_source: GO:0043249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. [GOC:devbiol, GOC:jl]


systematic_name: M10192
exact_source: GO:0043252
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043252
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators]


systematic_name: M14240
exact_source: GO:0043255
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043255
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. [GOC:jl]


systematic_name: M16600
exact_source: GO:0043266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M12534
exact_source: GO:0043267
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043267
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M11600
exact_source: GO:0043268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M15848
exact_source: GO:0043269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M12749
exact_source: GO:0043270
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043270
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M15775
exact_source: GO:0043271
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043271
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M23590
exact_source: GO:0043276
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043276
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix. [GOC:jl, http://www.copewithcytokines.de/]


systematic_name: M11346
exact_source: GO:0043277
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043277
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte. [GOC:rk, PMID:14685684]


systematic_name: M12438
exact_source: GO:0043279
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043279
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. [GOC:jl]


systematic_name: M46796
exact_source: GO:0043281
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043281
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis. [GOC:jl, GOC:mtg_apoptosis]


systematic_name: M11005
exact_source: GO:0043297
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043297
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. [GOC:go_curators, PMID:10854689, PMID:14729475, PMID:15196556]


systematic_name: M42791
exact_source: GO:0043299
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043299
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated exocytosis of secretory granules by a leukocyte. [GO_REF:0000022, GOC:add, ISBN:0781735149]


systematic_name: M15567
exact_source: GO:0043300
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043300
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of leukocyte degranulation. [GOC:add, ISBN:0781735149]


systematic_name: M14646
exact_source: GO:0043301
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043301
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the rate of leukocyte degranulation. [GOC:add, ISBN:0781735149]


systematic_name: M10766
exact_source: GO:0043302
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043302
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. [GOC:add, ISBN:0781735149]


systematic_name: M48446
exact_source: GO:0043304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of mast cell degranulation. [ISBN:0781735149]


systematic_name: M48447
exact_source: GO:0043306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of mast cell degranulation. [ISBN:0781735149]


systematic_name: M23593
exact_source: GO:0043307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:add, ISBN:0781735149]


systematic_name: M42792
exact_source: GO:0043312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil. [ISBN:0781735149]


systematic_name: M23594
exact_source: GO:0043313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of neutrophil degranulation. [ISBN:0781735149]


systematic_name: M23595
exact_source: GO:0043320
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043320
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. [ISBN:0781735149]


systematic_name: M34169
exact_source: GO:0043328
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043328
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway. [GOC:jl, PMID:11511343]


systematic_name: M15192
exact_source: GO:0043331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. [GOC:jl]


systematic_name: M45871
exact_source: GO:0043335
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043335
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state. [GOC:mlg]


systematic_name: M23596
exact_source: GO:0043353
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043353
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. [GOC:go_curators]


systematic_name: M48448
exact_source: GO:0043354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus. [GOC:go_curators]


systematic_name: M29177
exact_source: GO:0043367
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043367
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell. [CL:0000624, ISBN:0781735149]


systematic_name: M13180
exact_source: GO:0043368
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043368
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death. [ISBN:0781735149, PMID:12414722]


systematic_name: M14195
exact_source: GO:0043369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells. [ISBN:0781735149]


systematic_name: M23597
exact_source: GO:0043370
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043370
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. [GOC:add, GOC:pr, ISBN:0781735149]


systematic_name: M12266
exact_source: GO:0043371
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043371
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation. [GOC:add, GOC:pr, ISBN:0781735149]


systematic_name: M29178
exact_source: GO:0043372
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043372
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation. [GOC:add, GOC:pr, ISBN:0781735149]


systematic_name: M23599
exact_source: GO:0043374
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043374
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell. [ISBN:0781735149]


systematic_name: M23600
exact_source: GO:0043376
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043376
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation. [GOC:add, ISBN:0781735149]


systematic_name: M40433
exact_source: GO:0043378
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043378
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation. [GOC:add, ISBN:0781735149]


systematic_name: M23601
exact_source: GO:0043382
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043382
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of memory T cell differentiation. [ISBN:0781735149]


systematic_name: M14209
exact_source: GO:0043383
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043383
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of elimination of immature T cells which react strongly with self-antigens. [ISBN:0781735149, PMID:12414722]


systematic_name: M42793
exact_source: GO:0043385
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043385
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. [GOC:jl]


systematic_name: M19355
exact_source: GO:0043388
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043388
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb]


systematic_name: M8840
exact_source: GO:0043392
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043392
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). [GOC:dph, GOC:jl, GOC:tb]


systematic_name: M34170
exact_source: GO:0043400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland. [PMID:11027914]


systematic_name: M14771
exact_source: GO:0043401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by a steroid hormone binding to a receptor. [PMID:12606724]


systematic_name: M10415
exact_source: GO:0043403
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043403
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. [GOC:ef, GOC:mtg_muscle, PMID:12021255, PMID:16607119]


systematic_name: M14969
exact_source: GO:0043405
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043405
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of MAP kinase activity. [GOC:dph, GOC:go_curators]


systematic_name: M15225
exact_source: GO:0043406
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043406
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of MAP kinase activity. [GOC:dph, GOC:go_curators]


systematic_name: M10128
exact_source: GO:0043407
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043407
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity. [GOC:dph, GOC:go_curators]


systematic_name: M11738
exact_source: GO:0043409
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043409
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. [GOC:go_curators]


systematic_name: M11151
exact_source: GO:0043410
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043410
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade. [GOC:go_curators]


systematic_name: M46797
exact_source: GO:0043414
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043414
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. [GOC:go_curators]


systematic_name: M2649
exact_source: GO:0043433
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043433
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:jl]


systematic_name: M23605
exact_source: GO:0043434
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043434
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone]


systematic_name: M23606
exact_source: GO:0043435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response. [PMID:11027914, PMID:15134857, Wikipedia:Corticotropin-releasing_hormone]


systematic_name: M15678
exact_source: GO:0043455
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043455
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. [GOC:jl]


systematic_name: M45148
exact_source: GO:0043456
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043456
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis. [GOC:jl]


systematic_name: M15348
exact_source: GO:0043457
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043457
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds. [GOC:jl]


systematic_name: M15085
exact_source: GO:0043467
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043467
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. [GOC:jl]


systematic_name: M16356
exact_source: GO:0043470
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043470
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. [GOC:mlg]


systematic_name: M12025
exact_source: GO:0043473
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043473
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. [GOC:jl]


systematic_name: M16896
exact_source: GO:0043476
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043476
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. [GOC:jl]


systematic_name: M16816
exact_source: GO:0043484
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043484
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:jl]


systematic_name: M13074
exact_source: GO:0043491
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043491
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway. [PMID:20517722, PMID:22952397]


systematic_name: M13109
exact_source: GO:0043500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307]


systematic_name: M10779
exact_source: GO:0043501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307]


systematic_name: M16102
exact_source: GO:0043502
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043502
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of muscle adaptation. [GOC:go_curators, GOC:mtg_muscle]


systematic_name: M23610
exact_source: GO:0043504
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043504
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of restoring mitochondrial DNA after damage. [PMID:12565799, PMID:15189144, PMID:16050976]


systematic_name: M15527
exact_source: GO:0043507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of JUN kinase activity. [GOC:jl]


systematic_name: M11419
exact_source: GO:0043508
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043508
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity. [GOC:jl]


systematic_name: M11797
exact_source: GO:0043516
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043516
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:jl]


systematic_name: M10314
exact_source: GO:0043517
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043517
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:jl]


systematic_name: M16832
exact_source: GO:0043518
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043518
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:jl]


systematic_name: M9009
exact_source: GO:0043523
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043523
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. [GOC:go_curators, GOC:mtg_apoptosis]


systematic_name: M10229
exact_source: GO:0043524
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043524
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. [GOC:go_curators, GOC:mtg_apoptosis]


systematic_name: M16430
exact_source: GO:0043525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. [GOC:go_curators, GOC:mtg_apoptosis]


systematic_name: M12259
exact_source: GO:0043534
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043534
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. [PMID:11166264]


systematic_name: M16505
exact_source: GO:0043536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. [GOC:go_curators]


systematic_name: M10771
exact_source: GO:0043537
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043537
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. [GOC:go_curators]


systematic_name: M7145
exact_source: GO:0043542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. [GOC:go_curators]


systematic_name: M15586
exact_source: GO:0043543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid. [GOC:jl]


systematic_name: M45872
exact_source: GO:0043549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:bf]


systematic_name: M13017
exact_source: GO:0043550
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043550
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. [GOC:bf]


systematic_name: M10435
exact_source: GO:0043555
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043555
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:jl]


systematic_name: M14939
exact_source: GO:0043558
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043558
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. [GOC:jl]


systematic_name: M48449
exact_source: GO:0043562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen. [GOC:jl]


systematic_name: M15094
exact_source: GO:0043567
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043567
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling. [GOC:bf]


systematic_name: M16863
exact_source: GO:0043568
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043568
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling. [GOC:bf]


systematic_name: M23612
exact_source: GO:0043569
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043569
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling. [GOC:bf]


systematic_name: M14575
exact_source: GO:0043574
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043574
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. [GOC:jl]


systematic_name: M16358
exact_source: GO:0043576
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043576
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. [GOC:jl]


systematic_name: M12465
exact_source: GO:0043583
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043583
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. [GOC:jl, ISBN:0192801023]


systematic_name: M12568
exact_source: GO:0043584
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043584
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). [GOC:jl]


systematic_name: M11649
exact_source: GO:0043586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. [GOC:jl, UBERON:0001723]


systematic_name: M23614
exact_source: GO:0043587
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043587
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. [GOC:jl, UBERON:0001723]


systematic_name: M15889
exact_source: GO:0043588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. [GOC:jl, UBERON:0002097]


systematic_name: M23615
exact_source: GO:0043589
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043589
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. [GOC:jl, UBERON:0002097]


systematic_name: M12925
exact_source: GO:0043603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. [GOC:curators]


systematic_name: M13137
exact_source: GO:0043604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. [GOC:curators]


systematic_name: M45873
exact_source: GO:0043605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. [GOC:curators]


systematic_name: M23616
exact_source: GO:0043615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. [CL:0000127, GOC:go_curators]


systematic_name: M10787
exact_source: GO:0043616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. [CL:0000311]


systematic_name: M13475
exact_source: GO:0043627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. [GOC:jl, ISBN:0198506732]


systematic_name: M48450
exact_source: GO:0043632
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043632
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule. [GOC:jl]


systematic_name: M10931
exact_source: GO:0043647
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043647
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. [GOC:jl]


systematic_name: M11851
exact_source: GO:0043648
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043648
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). [ISBN:0198506732]


systematic_name: M15883
exact_source: GO:0043649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. [ISBN:0198506732]


systematic_name: M12548
exact_source: GO:0043650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. [ISBN:0198506732]


systematic_name: M15245
exact_source: GO:0043651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. [Wikipedia:Linoleic_Acid]


systematic_name: M23620
exact_source: GO:0043652
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043652
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte. [GOC:rk, PMID:15536015]


systematic_name: M23621
exact_source: GO:0043653
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043653
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form. [GOC:mtg_apoptosis, GOC:rk, PMID:12867994]


systematic_name: M23622
exact_source: GO:0043654
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043654
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis. [GOC:rk, PMID:15536015]


systematic_name: M15004
exact_source: GO:0043666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein. [GOC:jp, PMID:11724821]


systematic_name: M13855
exact_source: GO:0043687
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043687
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. [GOC:jsg]


systematic_name: M15088
exact_source: GO:0043691
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043691
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism. [GOC:ecd, PMID:7751809]


systematic_name: M23623
exact_source: GO:0043696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors. [GOC:dph, GOC:pg]


systematic_name: M12896
exact_source: GO:0043903
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043903
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association. [GOC:jl]


systematic_name: M11284
exact_source: GO:0043922
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043922
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription. [GOC:jl]


systematic_name: M10847
exact_source: GO:0043923
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043923
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA. [GOC:jl]


systematic_name: M16526
exact_source: GO:0043950
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043950
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling. [GOC:jl]


systematic_name: M23624
exact_source: GO:0043951
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043951
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling. [GOC:jl]


systematic_name: M11267
exact_source: GO:0043954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0043954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The organization process that preserves a cellular component in a stable functional or structural state. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M46801
exact_source: GO:0044027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. [PMID:11898023, Wikipedia:Cpg_island]


systematic_name: M48451
exact_source: GO:0044029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes. [PMID:36150101, Wikipedia:Cpg_island]


systematic_name: M46802
exact_source: GO:0044042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. [GOC:jl]


systematic_name: M14237
exact_source: GO:0044057
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044057
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. [GOC:jl]


systematic_name: M14082
exact_source: GO:0044058
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044058
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [GOC:jl]


systematic_name: M12886
exact_source: GO:0044060
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044060
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. [GOC:jl]


systematic_name: M12879
exact_source: GO:0044062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. [GOC:jl]


systematic_name: M10920
exact_source: GO:0044065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. [GOC:jl]


systematic_name: M16202
exact_source: GO:0044070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jl]


systematic_name: M11589
exact_source: GO:0044087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. [GOC:jl]


systematic_name: M11432
exact_source: GO:0044088
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044088
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. [GOC:jl, GOC:mah]


systematic_name: M12404
exact_source: GO:0044089
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044089
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. [GOC:jl]


systematic_name: M10804
exact_source: GO:0044090
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044090
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. [GOC:jl, GOC:mah]


systematic_name: M10667
exact_source: GO:0044091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. [GOC:jl]


systematic_name: M13509
exact_source: GO:0044092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GO:jl]


systematic_name: M12495
exact_source: GO:0044093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. [GO:jl]


systematic_name: M42797
exact_source: GO:0044208
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044208
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP). [GOC:ecd, PMID:10888601]


systematic_name: M42798
exact_source: GO:0044209
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044209
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis. [GOC:ecd, GOC:jl, PMID:8917457, PMID:9864350]


systematic_name: M11799
exact_source: GO:0044241
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044241
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism. [GOC:go_curators]


systematic_name: M5981
exact_source: GO:0044242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells. [GOC:jl]


systematic_name: M4776
exact_source: GO:0044248
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044248
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. [GOC:jl]


systematic_name: M12583
exact_source: GO:0044272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. [GOC:jl]


systematic_name: M12614
exact_source: GO:0044273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. [GOC:jl]


systematic_name: M40437
exact_source: GO:0044281
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044281
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:vw]


systematic_name: M14245
exact_source: GO:0044282
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044282
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:vw]


systematic_name: M12217
exact_source: GO:0044283
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044283
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. [GOC:curators, GOC:pde, GOC:vw]


systematic_name: M23636
exact_source: GO:0044314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein. [PMID:19345326]


systematic_name: M15436
exact_source: GO:0044320
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044320
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. [GOC:yaf]


systematic_name: M16799
exact_source: GO:0044321
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044321
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism]. [GOC:yaf]


systematic_name: M23637
exact_source: GO:0044331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains. [GOC:ha, GOC:hjd, GOC:jl, PMID:10923970]


systematic_name: M23640
exact_source: GO:0044341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions. [GOC:BHF, GOC:jl]


systematic_name: M23641
exact_source: GO:0044342
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044342
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. [GOC:jl, GOC:yaf]


systematic_name: M23642
exact_source: GO:0044346
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044346
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf]


systematic_name: M23643
exact_source: GO:0044351
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044351
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size. [PMID:14732047]


systematic_name: M10273
exact_source: GO:0044380
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044380
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. [GOC:jl]


systematic_name: M40438
exact_source: GO:0044381
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044381
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus. [GOC:BHF, PMID:19079291]


systematic_name: M23645
exact_source: GO:0044387
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044387
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase. [GOC:jl]


systematic_name: M34173
exact_source: GO:0044403
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044403
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. [GOC:cc, PMID:31257129]


systematic_name: M23646
exact_source: GO:0044406
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044406
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of a symbiont to its host via either adhesion molecules, general stickiness, or other mechanisms. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:bf, GOC:cc, GOC:dos, GOC:jl]


systematic_name: M29184
exact_source: GO:0044409
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044409
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:vw]


systematic_name: M15070
exact_source: GO:0044458
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044458
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a motile cilium. [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf]


systematic_name: M34174
exact_source: GO:0044528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs. [GOC:al, GOC:jl]


systematic_name: M48453
exact_source: GO:0044550
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044550
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. [GOC:jl]


systematic_name: M23653
exact_source: GO:0044557
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044557
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. [GOC:jl]


systematic_name: M23654
exact_source: GO:0044571
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044571
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster. [GOC:jl, GOC:mengo_curators, GOC:pde, GOC:tt, GOC:vw, PMID:15952888]


systematic_name: M45874
exact_source: GO:0044572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster. [GOC:jl, GOC:mengo_curators, GOC:pde, GOC:tt, GOC:vw, PMID:15952888]


systematic_name: M23655
exact_source: GO:0044650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly. [GOC:jl]


systematic_name: M23656
exact_source: GO:0044691
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044691
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The tooth development process in which the teeth enter the mouth and become visible. [Wikipedia:Tooth_eruption]


systematic_name: M14200
exact_source: GO:0044706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A multicellular organism process which involves another multicellular organism of the same or different species. [GOC:jl]


systematic_name: M46803
exact_source: GO:0044721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane. [PMID:21976670]


systematic_name: M46804
exact_source: GO:0044725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process. [GOC:sp, PMID:22868271]


systematic_name: M48454
exact_source: GO:0044727
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044727
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division. [GOC:sp, PMID:22868271]


systematic_name: M42803
exact_source: GO:0044752
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044752
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus. [PMID:21325635]


systematic_name: M11012
exact_source: GO:0044770
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044770
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process by which a cell commits to entering the next cell cycle phase. [GOC:mtg_cell_cycle]


systematic_name: M23659
exact_source: GO:0044771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase. [GOC:mtg_cell_cycle]


systematic_name: M42804
exact_source: GO:0044772
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044772
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase. [GOC:mtg_cell_cycle]


systematic_name: M13712
exact_source: GO:0044774
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044774
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction. [GOC:mtg_cell_cycle]


systematic_name: M13049
exact_source: GO:0044782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. [GOC:cilia, GOC:jl]


systematic_name: M46805
exact_source: GO:0044785
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044785
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis. [GOC:mtg_cell_cycle]


systematic_name: M11671
exact_source: GO:0044788
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044788
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected. [GOC:jl]


systematic_name: M42805
exact_source: GO:0044790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells. [GOC:jl, PMID:18305167]


systematic_name: M23662
exact_source: GO:0044793
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044793
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected. [GOC:jl]


systematic_name: M14060
exact_source: GO:0044794
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044794
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected. [GOC:jl]


systematic_name: M23664
exact_source: GO:0044804
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044804
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded. [GOC:autophagy, GOC:jl, PMID:24013549]


systematic_name: M23665
exact_source: GO:0044806
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044806
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'. [GOC:jl, GOC:se, PMID:23657261]


systematic_name: M11745
exact_source: GO:0044818
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044818
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle. [GOC:mtg_cell_cycle]


systematic_name: M34177
exact_source: GO:0044819
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044819
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle. [GOC:mtg_cell_cycle]


systematic_name: M23666
exact_source: GO:0044827
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044827
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism modulates the frequency, rate or extent of viral genome replication. [GOC:jl]


systematic_name: M23667
exact_source: GO:0044828
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044828
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication. [GOC:jl]


systematic_name: M23668
exact_source: GO:0044829
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044829
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication. [GOC:jl]


systematic_name: M45151
exact_source: GO:0044830
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044830
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication. [GOC:jl]


systematic_name: M23669
exact_source: GO:0044837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring. [GOC:mtg_cell_cycle]


systematic_name: M16851
exact_source: GO:0044849
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044849
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur. [GOC:jl, Wikipedia:Estrous_cycle]


systematic_name: M34178
exact_source: GO:0044851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. [GOC:jl]


systematic_name: M23671
exact_source: GO:0044854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft. [GOC:jl]


systematic_name: M23672
exact_source: GO:0044857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts. [GOC:jl]


systematic_name: M45152
exact_source: GO:0044860
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044860
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft. [GOC:jl]


systematic_name: M14212
exact_source: GO:0044872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0044872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a lipoprotein is transported to, or maintained in, a specific location. [GOC:jl]


systematic_name: M23673
exact_source: GO:0045002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats. [PMID:11606529]


systematic_name: M23674
exact_source: GO:0045003
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045003
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break. [PMID:10357855]


systematic_name: M10043
exact_source: GO:0045005
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045005
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair. [GOC:mah, GOC:vw]


systematic_name: M23675
exact_source: GO:0045006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil. [GOC:ai]


systematic_name: M23676
exact_source: GO:0045008
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045008
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar. [GOC:ai]


systematic_name: M15725
exact_source: GO:0045010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament. [ISBN:0815316194]


systematic_name: M13721
exact_source: GO:0045017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone. [GOC:ai]


systematic_name: M23678
exact_source: GO:0045023
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045023
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression. [GOC:mtg_cell_cycle, ISBN:0716731363]


systematic_name: M14815
exact_source: GO:0045026
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045026
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. [GOC:elh, GOC:mtg_muscle]


systematic_name: M23679
exact_source: GO:0045039
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045039
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane. [GOC:mcc, GOC:vw, PMID:18672008]


systematic_name: M48455
exact_source: GO:0045040
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045040
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes. [GOC:mcc, GOC:vw, PMID:18672008]


systematic_name: M23681
exact_source: GO:0045046
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045046
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import. [ISBN:0716731363, PMID:11687502]


systematic_name: M23682
exact_source: GO:0045048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane. [ISBN:0716731363]


systematic_name: M40440
exact_source: GO:0045050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix. [ISBN:0716731363]


systematic_name: M23683
exact_source: GO:0045053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known. [ISBN:0716731363]


systematic_name: M34179
exact_source: GO:0045054
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045054
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space. [GOC:mah, ISBN:0716731363]


systematic_name: M42806
exact_source: GO:0045055
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045055
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. [GOC:mah, ISBN:0716731363]


systematic_name: M16224
exact_source: GO:0045056
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045056
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. [ISBN:0716731363]


systematic_name: M16724
exact_source: GO:0045058
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045058
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. [ISBN:0781735149, PMID:12414722]


systematic_name: M23684
exact_source: GO:0045059
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045059
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death. [ISBN:0781735149, PMID:12414722]


systematic_name: M23685
exact_source: GO:0045063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. [CL:0000545, GOC:ebc]


systematic_name: M23686
exact_source: GO:0045064
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045064
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4. [CL:0000546, GOC:ebc]


systematic_name: M23687
exact_source: GO:0045066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types. [ISBN:0781735149]


systematic_name: M11124
exact_source: GO:0045070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of viral genome replication. [GOC:ai]


systematic_name: M15907
exact_source: GO:0045071
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045071
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication. [GOC:go_curators]


systematic_name: M3064
exact_source: GO:0045087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]


systematic_name: M34180
exact_source: GO:0045088
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045088
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. [GOC:ebc]


systematic_name: M10384
exact_source: GO:0045103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. [GOC:ai]


systematic_name: M10607
exact_source: GO:0045109
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045109
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. [GOC:ai]


systematic_name: M23691
exact_source: GO:0045110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. [ISBN:0716731363]


systematic_name: M23692
exact_source: GO:0045112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules. [GOC:go_curators, ISBN:0198506732]


systematic_name: M34182
exact_source: GO:0045113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins. [GOC:go_curators]


systematic_name: M16590
exact_source: GO:0045117
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045117
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane. [GOC:go_curators, ISBN:3527307206, Wikipedia:Azole]


systematic_name: M10086
exact_source: GO:0045132
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045132
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. [GOC:ai, GOC:mah]


systematic_name: M23693
exact_source: GO:0045136
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045136
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion. [GOC:ai]


systematic_name: M16813
exact_source: GO:0045137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. [GOC:ai]


systematic_name: M14947
exact_source: GO:0045143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. [GOC:ai, ISBN:0815316194]


systematic_name: M13511
exact_source: GO:0045161
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045161
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation. [PMID:11456440]


systematic_name: M23695
exact_source: GO:0045162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization. [PMID:11456440]


systematic_name: M15945
exact_source: GO:0045165
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045165
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate. [ISBN:0716731185]


systematic_name: M10070
exact_source: GO:0045176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained in, apical regions of the cell. [GOC:bf]


systematic_name: M23696
exact_source: GO:0045185
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045185
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. [GOC:bf]


systematic_name: M46806
exact_source: GO:0045188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. [GOC:go_curators]


systematic_name: M23697
exact_source: GO:0045198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specification and formation of the apicobasal polarity of an epithelial cell. [GOC:ascb_2009, GOC:bf, GOC:dph, GOC:tb]


systematic_name: M11569
exact_source: GO:0045214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. [GOC:bf]


systematic_name: M23698
exact_source: GO:0045216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M40442
exact_source: GO:0045229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M15250
exact_source: GO:0045292
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045292
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. [GOC:krc, ISBN:0879695897, PMID:18458335]


systematic_name: M23700
exact_source: GO:0045324
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045324
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport. [PMID:11872141]


systematic_name: M15594
exact_source: GO:0045333
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045333
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration). [GOC:das, ISBN:0140513590, ISBN:0198506732]


systematic_name: M29186
exact_source: GO:0045338
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045338
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation. [GOC:go_curators]


systematic_name: M23702
exact_source: GO:0045341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I. [GOC:go_curators]


systematic_name: M23703
exact_source: GO:0045342
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045342
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II. [GOC:go_curators]


systematic_name: M23704
exact_source: GO:0045345
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045345
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I. [GOC:go_curators]


systematic_name: M23705
exact_source: GO:0045347
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045347
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. [GOC:go_curators]


systematic_name: M23706
exact_source: GO:0045348
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045348
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II. [GOC:go_curators]


systematic_name: M14158
exact_source: GO:0045444
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045444
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. [CL:0000136, GOC:go_curators]


systematic_name: M13632
exact_source: GO:0045445
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045445
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. [CL:0000056, GOC:go_curators, GOC:mtg_muscle]


systematic_name: M15668
exact_source: GO:0045453
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045453
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. [GOC:mah, PMID:10968780]


systematic_name: M12813
exact_source: GO:0045454
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045454
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that maintains the redox environment of a cell or compartment within a cell. [GOC:ai, GOC:dph, GOC:tb]


systematic_name: M10221
exact_source: GO:0045471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. [GOC:go_curators]


systematic_name: M15946
exact_source: GO:0045472
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045472
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. [GOC:go_curators]


systematic_name: M23715
exact_source: GO:0045475
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045475
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The rhythm of the locomotor activity of an organism during its 24 hour activity cycle. [GOC:go_curators]


systematic_name: M12966
exact_source: GO:0045494
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045494
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light. [CL:0000210, GOC:bf, GOC:rl]


systematic_name: M12147
exact_source: GO:0045540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. [GOC:go_curators]


systematic_name: M34185
exact_source: GO:0045542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol. [GOC:go_curators]


systematic_name: M12306
exact_source: GO:0045576
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045576
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M13200
exact_source: GO:0045577
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045577
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of B cell differentiation. [GOC:go_curators]


systematic_name: M29191
exact_source: GO:0045578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. [GOC:go_curators]


systematic_name: M15028
exact_source: GO:0045579
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045579
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of B cell differentiation. [GOC:go_curators]


systematic_name: M48457
exact_source: GO:0045581
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045581
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. [GOC:go_curators]


systematic_name: M23718
exact_source: GO:0045586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation. [GOC:go_curators]


systematic_name: M34186
exact_source: GO:0045588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation. [GOC:go_curators]


systematic_name: M23719
exact_source: GO:0045590
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045590
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells. [ISBN:0781735149]


systematic_name: M23720
exact_source: GO:0045591
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045591
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells. [ISBN:0781735149]


systematic_name: M4547
exact_source: GO:0045595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. [GOC:go_curators]


systematic_name: M9266
exact_source: GO:0045596
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045596
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. [GOC:go_curators]


systematic_name: M12912
exact_source: GO:0045597
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045597
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of cell differentiation. [GOC:go_curators]


systematic_name: M10293
exact_source: GO:0045598
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045598
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of adipocyte differentiation. [GOC:go_curators]


systematic_name: M10687
exact_source: GO:0045599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. [GOC:go_curators]


systematic_name: M10890
exact_source: GO:0045600
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045600
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. [GOC:go_curators]


systematic_name: M11127
exact_source: GO:0045601
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045601
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of endothelial cell differentiation. [GOC:go_curators]


systematic_name: M23721
exact_source: GO:0045602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. [GOC:go_curators]


systematic_name: M10482
exact_source: GO:0045603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. [GOC:go_curators]


systematic_name: M23722
exact_source: GO:0045607
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045607
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. [GOC:go_curators]


systematic_name: M14926
exact_source: GO:0045616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of keratinocyte differentiation. [GOC:go_curators]


systematic_name: M23723
exact_source: GO:0045617
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045617
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. [GOC:go_curators]


systematic_name: M10630
exact_source: GO:0045618
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045618
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. [GOC:go_curators]


systematic_name: M13520
exact_source: GO:0045619
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045619
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of lymphocyte differentiation. [GOC:go_curators]


systematic_name: M16917
exact_source: GO:0045620
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045620
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. [GOC:go_curators]


systematic_name: M14088
exact_source: GO:0045621
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045621
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. [GOC:go_curators]


systematic_name: M11275
exact_source: GO:0045622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of T-helper cell differentiation. [GOC:go_curators]


systematic_name: M23724
exact_source: GO:0045623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation. [GOC:go_curators]


systematic_name: M13909
exact_source: GO:0045624
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045624
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation. [GOC:go_curators]


systematic_name: M23725
exact_source: GO:0045625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation. [GOC:go_curators]


systematic_name: M23726
exact_source: GO:0045627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation. [GOC:go_curators]


systematic_name: M11638
exact_source: GO:0045628
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045628
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation. [GOC:go_curators]


systematic_name: M46807
exact_source: GO:0045629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation. [GOC:go_curators]


systematic_name: M23727
exact_source: GO:0045630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation. [GOC:go_curators]


systematic_name: M23728
exact_source: GO:0045634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of melanocyte differentiation. [GOC:go_curators]


systematic_name: M42811
exact_source: GO:0045636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. [GOC:go_curators]


systematic_name: M8700
exact_source: GO:0045637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of myeloid cell differentiation. [GOC:go_curators]


systematic_name: M14891
exact_source: GO:0045638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. [GOC:go_curators]


systematic_name: M13875
exact_source: GO:0045639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. [GOC:go_curators]


systematic_name: M13902
exact_source: GO:0045646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of erythrocyte differentiation. [GOC:go_curators]


systematic_name: M23730
exact_source: GO:0045647
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045647
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. [GOC:go_curators]


systematic_name: M10440
exact_source: GO:0045648
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045648
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. [GOC:go_curators]


systematic_name: M15291
exact_source: GO:0045649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of macrophage differentiation. [GOC:go_curators]


systematic_name: M23731
exact_source: GO:0045650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. [GOC:go_curators]


systematic_name: M16762
exact_source: GO:0045651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of macrophage differentiation. [GOC:go_curators]


systematic_name: M12954
exact_source: GO:0045652
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045652
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. [GOC:go_curators]


systematic_name: M14703
exact_source: GO:0045653
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045653
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. [GOC:go_curators]


systematic_name: M23732
exact_source: GO:0045654
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045654
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. [GOC:go_curators]


systematic_name: M14623
exact_source: GO:0045655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of monocyte differentiation. [GOC:go_curators]


systematic_name: M23733
exact_source: GO:0045656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. [GOC:go_curators]


systematic_name: M23734
exact_source: GO:0045657
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045657
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of monocyte differentiation. [GOC:go_curators]


systematic_name: M12330
exact_source: GO:0045661
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045661
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:go_curators, GOC:mtg_muscle]


systematic_name: M13403
exact_source: GO:0045662
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045662
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:go_curators, GOC:mtg_muscle]


systematic_name: M14562
exact_source: GO:0045663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:go_curators, GOC:mtg_muscle]


systematic_name: M12739
exact_source: GO:0045664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of neuron differentiation. [GOC:go_curators]


systematic_name: M10363
exact_source: GO:0045665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. [GOC:go_curators]


systematic_name: M10925
exact_source: GO:0045666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of neuron differentiation. [GOC:go_curators]


systematic_name: M14392
exact_source: GO:0045667
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045667
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of osteoblast differentiation. [GOC:go_curators]


systematic_name: M15707
exact_source: GO:0045668
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045668
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. [GOC:go_curators]


systematic_name: M15118
exact_source: GO:0045669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. [GOC:go_curators]


systematic_name: M10369
exact_source: GO:0045670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators]


systematic_name: M16815
exact_source: GO:0045671
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045671
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators]


systematic_name: M13018
exact_source: GO:0045672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators]


systematic_name: M10669
exact_source: GO:0045682
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045682
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of epidermis development. [GOC:go_curators]


systematic_name: M13963
exact_source: GO:0045683
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045683
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. [GOC:go_curators]


systematic_name: M13685
exact_source: GO:0045684
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045684
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of epidermis development. [GOC:go_curators]


systematic_name: M15023
exact_source: GO:0045685
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045685
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of glia cell differentiation. [GOC:go_curators]


systematic_name: M11035
exact_source: GO:0045686
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045686
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. [GOC:go_curators]


systematic_name: M11043
exact_source: GO:0045687
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045687
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of glia cell differentiation. [GOC:go_curators]


systematic_name: M15179
exact_source: GO:0045717
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045717
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. [GOC:go_curators]


systematic_name: M15808
exact_source: GO:0045721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. [GOC:go_curators]


systematic_name: M16444
exact_source: GO:0045722
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045722
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of gluconeogenesis. [GOC:go_curators]


systematic_name: M11966
exact_source: GO:0045723
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045723
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids. [GOC:go_curators]


systematic_name: M23736
exact_source: GO:0045724
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045724
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the formation of a cilium. [GOC:cilia, GOC:go_curators]


systematic_name: M48458
exact_source: GO:0045725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. [GOC:go_curators]


systematic_name: M16899
exact_source: GO:0045727
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045727
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M13734
exact_source: GO:0045730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. [ISBN:0198506732]


systematic_name: M11089
exact_source: GO:0045732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. [GOC:go_curators]


systematic_name: M46808
exact_source: GO:0045736
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045736
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity. [GOC:go_curators, GOC:pr]


systematic_name: M10904
exact_source: GO:0045738
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045738
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair. [GOC:go_curators]


systematic_name: M13735
exact_source: GO:0045739
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045739
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of DNA repair. [GOC:go_curators]


systematic_name: M10227
exact_source: GO:0045740
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045740
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of DNA replication. [GOC:go_curators]


systematic_name: M23737
exact_source: GO:0045743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. [GOC:go_curators]


systematic_name: M23738
exact_source: GO:0045744
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045744
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators]


systematic_name: M23739
exact_source: GO:0045745
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045745
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. [GOC:go_curators]


systematic_name: M11627
exact_source: GO:0045746
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045746
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway. [GOC:go_curators]


systematic_name: M11070
exact_source: GO:0045747
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045747
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway. [GOC:go_curators]


systematic_name: M23740
exact_source: GO:0045759
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045759
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:go_curators]


systematic_name: M11161
exact_source: GO:0045760
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045760
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:go_curators]


systematic_name: M12312
exact_source: GO:0045761
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045761
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of adenylate cyclase activity. [GOC:go_curators]


systematic_name: M10923
exact_source: GO:0045762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity. [GOC:go_curators]


systematic_name: M13512
exact_source: GO:0045773
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045773
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of axon extension. [GOC:go_curators]


systematic_name: M14221
exact_source: GO:0045776
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045776
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which the force of blood traveling through the circulatory system is decreased. [GOC:go_curators, GOC:mtg_cardio]


systematic_name: M14432
exact_source: GO:0045777
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045777
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which the force of blood traveling through the circulatory system is increased. [GOC:go_curators, GOC:mtg_cardio]


systematic_name: M16952
exact_source: GO:0045778
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045778
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:go_curators]


systematic_name: M23741
exact_source: GO:0045780
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045780
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of bone resorption. [GOC:go_curators]


systematic_name: M11923
exact_source: GO:0045785
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045785
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of cell adhesion. [GOC:go_curators]


systematic_name: M12829
exact_source: GO:0045786
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045786
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M17705
exact_source: GO:0045787
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045787
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of progression through the cell cycle. [GOC:go_curators]


systematic_name: M11212
exact_source: GO:0045806
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045806
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. [GOC:go_curators]


systematic_name: M10433
exact_source: GO:0045807
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045807
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of endocytosis. [GOC:go_curators]


systematic_name: M12274
exact_source: GO:0045814
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045814
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation. [PMID:22243696]


systematic_name: M11125
exact_source: GO:0045824
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045824
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. [GOC:go_curators]


systematic_name: M23747
exact_source: GO:0045830
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045830
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of isotype switching. [GOC:go_curators]


systematic_name: M10685
exact_source: GO:0045833
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045833
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. [GOC:go_curators]


systematic_name: M15089
exact_source: GO:0045834
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045834
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. [GOC:go_curators]


systematic_name: M11402
exact_source: GO:0045835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. [GOC:go_curators]


systematic_name: M23749
exact_source: GO:0045837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:go_curators]


systematic_name: M23750
exact_source: GO:0045838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:go_curators]


systematic_name: M45877
exact_source: GO:0045851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion. [GOC:go_curators]


systematic_name: M46810
exact_source: GO:0045860
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045860
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of protein kinase activity. [GOC:go_curators]


systematic_name: M10339
exact_source: GO:0045861
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045861
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. [GOC:go_curators]


systematic_name: M14936
exact_source: GO:0045862
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045862
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. [GOC:go_curators]


systematic_name: M23752
exact_source: GO:0045869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate. [GOC:go_curators]


systematic_name: M23753
exact_source: GO:0045875
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045875
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion. [GOC:go_curators]


systematic_name: M23754
exact_source: GO:0045876
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045876
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion. [GOC:go_curators]


systematic_name: M13653
exact_source: GO:0045879
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045879
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling. [GOC:go_curators]


systematic_name: M15718
exact_source: GO:0045880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of smoothened signaling. [GOC:go_curators]


systematic_name: M12247
exact_source: GO:0045898
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045898
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly. [GOC:go_curators]


systematic_name: M29193
exact_source: GO:0045900
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045900
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. [GOC:go_curators]


systematic_name: M23756
exact_source: GO:0045906
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045906
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction. [GOC:go_curators]


systematic_name: M12386
exact_source: GO:0045907
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045907
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of vasoconstriction. [GOC:go_curators]


systematic_name: M10992
exact_source: GO:0045910
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045910
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination. [GOC:go_curators]


systematic_name: M15127
exact_source: GO:0045911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of DNA recombination. [GOC:go_curators]


systematic_name: M14102
exact_source: GO:0045912
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045912
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. [GOC:go_curators]


systematic_name: M11721
exact_source: GO:0045913
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045913
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. [GOC:go_curators]


systematic_name: M42813
exact_source: GO:0045915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. [GOC:go_curators]


systematic_name: M23757
exact_source: GO:0045916
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045916
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation. [GOC:go_curators]


systematic_name: M23758
exact_source: GO:0045917
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045917
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of complement activation. [GOC:go_curators]


systematic_name: M11437
exact_source: GO:0045920
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045920
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. [GOC:go_curators]


systematic_name: M13138
exact_source: GO:0045921
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045921
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of exocytosis. [GOC:go_curators]


systematic_name: M16838
exact_source: GO:0045922
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045922
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. [GOC:go_curators]


systematic_name: M15385
exact_source: GO:0045923
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045923
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. [GOC:go_curators]


systematic_name: M40445
exact_source: GO:0045924
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045924
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M6071
exact_source: GO:0045926
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045926
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. [GOC:go_curators]


systematic_name: M14190
exact_source: GO:0045927
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045927
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. [GOC:go_curators]


systematic_name: M13508
exact_source: GO:0045930
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045930
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M11049
exact_source: GO:0045931
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045931
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M10753
exact_source: GO:0045932
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045932
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. [GOC:go_curators]


systematic_name: M12252
exact_source: GO:0045933
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045933
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of muscle contraction. [GOC:go_curators]


systematic_name: M23761
exact_source: GO:0045934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. [GOC:go_curators]


systematic_name: M11052
exact_source: GO:0045939
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045939
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. [GOC:go_curators]


systematic_name: M16578
exact_source: GO:0045940
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045940
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. [GOC:go_curators]


systematic_name: M23764
exact_source: GO:0045943
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045943
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I. [GOC:go_curators, GOC:txnOH]


systematic_name: M23765
exact_source: GO:0045944
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045944
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. [GOC:go_curators, GOC:txnOH]


systematic_name: M23766
exact_source: GO:0045945
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045945
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III. [GOC:go_curators, GOC:txnOH]


systematic_name: M11930
exact_source: GO:0045947
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045947
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. [GOC:go_curators]


systematic_name: M12031
exact_source: GO:0045948
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045948
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of translational initiation. [GOC:go_curators]


systematic_name: M48459
exact_source: GO:0045954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity. [GOC:add, ISBN:0781735149]


systematic_name: M11236
exact_source: GO:0045955
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045955
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis. [GOC:go_curators]


systematic_name: M10430
exact_source: GO:0045956
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045956
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis. [GOC:go_curators]


systematic_name: M29197
exact_source: GO:0045980
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045980
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. [GOC:go_curators]


systematic_name: M29198
exact_source: GO:0045981
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045981
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. [GOC:go_curators]


systematic_name: M14169
exact_source: GO:0045986
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045986
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. [GOC:go_curators]


systematic_name: M12814
exact_source: GO:0045987
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045987
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. [GOC:go_curators]


systematic_name: M23767
exact_source: GO:0045988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. [GOC:go_curators]


systematic_name: M12323
exact_source: GO:0045989
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045989
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of striated muscle contraction. [GOC:go_curators]


systematic_name: M23768
exact_source: GO:0045990
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045990
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. [GOC:go_curators, GOC:mah, PMID:18359269, PMID:9618445]


systematic_name: M15221
exact_source: GO:0045995
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0045995
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of embryonic development. [GOC:go_curators]


systematic_name: M23769
exact_source: GO:0046007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation. [GOC:go_curators]


systematic_name: M23770
exact_source: GO:0046015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involving glucose that modulates the frequency, rate or extent or transcription. [GOC:go_curators]


systematic_name: M46811
exact_source: GO:0046016
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046016
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involving glucose that activates or increases the rate of transcription. [GOC:go_curators]


systematic_name: M23771
exact_source: GO:0046034
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046034
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. [GOC:go_curators]


systematic_name: M40447
exact_source: GO:0046050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate. [GOC:go_curators]


systematic_name: M42815
exact_source: GO:0046053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate). [GOC:go_curators]


systematic_name: M45155
exact_source: GO:0046054
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046054
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate). [GOC:go_curators]


systematic_name: M29202
exact_source: GO:0046058
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046058
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). [GOC:go_curators]


systematic_name: M29204
exact_source: GO:0046068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate. [GOC:go_curators]


systematic_name: M46812
exact_source: GO:0046069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate. [GOC:go_curators]


systematic_name: M40448
exact_source: GO:0046073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). [GOC:go_curators]


systematic_name: M42816
exact_source: GO:0046075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate. [GOC:go_curators]


systematic_name: M34190
exact_source: GO:0046078
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046078
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate). [GOC:go_curators]


systematic_name: M23773
exact_source: GO:0046085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes. [GOC:go_curators]


systematic_name: M42818
exact_source: GO:0046087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside. [GOC:go_curators]


systematic_name: M42819
exact_source: GO:0046098
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046098
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important. [GOC:go_curators]


systematic_name: M42820
exact_source: GO:0046102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs. [GOC:go_curators]


systematic_name: M16916
exact_source: GO:0046112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. [GOC:ai]


systematic_name: M23774
exact_source: GO:0046113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. [GOC:ai]


systematic_name: M42821
exact_source: GO:0046121
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046121
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). [GOC:ai]


systematic_name: M42822
exact_source: GO:0046122
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046122
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). [GOC:ai]


systematic_name: M42823
exact_source: GO:0046125
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046125
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). [GOC:ai]


systematic_name: M42824
exact_source: GO:0046128
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046128
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. [GOC:ai]


systematic_name: M42825
exact_source: GO:0046130
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046130
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. [GOC:ai]


systematic_name: M46813
exact_source: GO:0046134
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046134
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:ai]


systematic_name: M15390
exact_source: GO:0046135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:ai]


systematic_name: M23775
exact_source: GO:0046137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. [GOC:ai]


systematic_name: M29207
exact_source: GO:0046146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine. [PMID:21871890]


systematic_name: M15363
exact_source: GO:0046148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. [ISBN:0198506732]


systematic_name: M45156
exact_source: GO:0046149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. [ISBN:0198506732]


systematic_name: M48460
exact_source: GO:0046160
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046160
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3. [GOC:curators]


systematic_name: M16620
exact_source: GO:0046164
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046164
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. [GOC:ai]


systematic_name: M16484
exact_source: GO:0046165
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046165
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. [GOC:ai]


systematic_name: M16513
exact_source: GO:0046173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. [GOC:curators]


systematic_name: M11137
exact_source: GO:0046174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. [GOC:curators]


systematic_name: M23776
exact_source: GO:0046184
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046184
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. [GOC:ai]


systematic_name: M11096
exact_source: GO:0046185
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046185
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. [GOC:ai]


systematic_name: M10438
exact_source: GO:0046189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. [GOC:ai]


systematic_name: M29209
exact_source: GO:0046321
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046321
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of fatty acid oxidation. [GOC:ai]


systematic_name: M23777
exact_source: GO:0046322
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046322
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation. [GOC:ai]


systematic_name: M34192
exact_source: GO:0046324
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046324
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. [GOC:ai]


systematic_name: M16320
exact_source: GO:0046325
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046325
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. [GOC:ai]


systematic_name: M40449
exact_source: GO:0046326
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046326
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle. [GOC:ai, GOC:dph, GOC:tb]


systematic_name: M40450
exact_source: GO:0046328
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046328
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade. [GOC:bf]


systematic_name: M14488
exact_source: GO:0046329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade. [GOC:bf]


systematic_name: M23778
exact_source: GO:0046330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade. [GOC:bf]


systematic_name: M29210
exact_source: GO:0046337
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046337
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes. [GOC:curators, ISBN:0198506732]


systematic_name: M15058
exact_source: GO:0046339
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046339
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. [PMID:11481335]


systematic_name: M45878
exact_source: GO:0046340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. [PMID:11717312]


systematic_name: M13698
exact_source: GO:0046348
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046348
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group. [GOC:curators]


systematic_name: M11449
exact_source: GO:0046349
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046349
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group. [GOC:curators]


systematic_name: M12988
exact_source: GO:0046364
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046364
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. [ISBN:0198506732]


systematic_name: M11279
exact_source: GO:0046365
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046365
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. [ISBN:0198506732]


systematic_name: M23781
exact_source: GO:0046390
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046390
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. [GOC:ai]


systematic_name: M29212
exact_source: GO:0046391
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046391
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate. [GOC:ai]


systematic_name: M14906
exact_source: GO:0046415
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046415
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals. [ISBN:0198506732]


systematic_name: M29213
exact_source: GO:0046426
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046426
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT. [GOC:bf]


systematic_name: M13815
exact_source: GO:0046434
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046434
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound. [GOC:ai]


systematic_name: M23782
exact_source: GO:0046456
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046456
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids. [ISBN:0198506732]


systematic_name: M16690
exact_source: GO:0046457
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046457
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure. [GOC:ai]


systematic_name: M12558
exact_source: GO:0046459
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046459
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. [Wikipedia:Fatty_acid_metabolism]


systematic_name: M14077
exact_source: GO:0046460
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046460
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity. [GOC:ai]


systematic_name: M13264
exact_source: GO:0046461
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046461
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity. [GOC:ai]


systematic_name: M29214
exact_source: GO:0046462
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046462
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. [ISBN:0198506732]


systematic_name: M45880
exact_source: GO:0046465
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046465
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes. [ISBN:0198506732]


systematic_name: M11628
exact_source: GO:0046466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane. [GOC:ai]


systematic_name: M16158
exact_source: GO:0046467
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046467
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. [GOC:ai]


systematic_name: M29215
exact_source: GO:0046469
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046469
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli. [ISBN:0198547684]


systematic_name: M10345
exact_source: GO:0046470
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046470
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes. [ISBN:0198506732]


systematic_name: M11658
exact_source: GO:0046471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes. [ISBN:0198506732]


systematic_name: M29216
exact_source: GO:0046473
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046473
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids. [ISBN:0198506732]


systematic_name: M42827
exact_source: GO:0046474
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046474
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. [ISBN:0198506732]


systematic_name: M14101
exact_source: GO:0046475
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046475
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. [ISBN:0198506732]


systematic_name: M23783
exact_source: GO:0046476
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046476
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. [GOC:ai]


systematic_name: M23784
exact_source: GO:0046477
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046477
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. [GOC:ai]


systematic_name: M12061
exact_source: GO:0046486
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046486
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis. [GOC:ai, PMID:8906569]


systematic_name: M13235
exact_source: GO:0046487
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046487
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH. [ISBN:0198506732]


systematic_name: M10397
exact_source: GO:0046488
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046488
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. [ISBN:0198506732]


systematic_name: M48461
exact_source: GO:0046492
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046492
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes. [GOC:yaf, PMID:29414780]


systematic_name: M12669
exact_source: GO:0046500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29218
exact_source: GO:0046501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation. [ISBN:0198506732]


systematic_name: M15197
exact_source: GO:0046503
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046503
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone. [GOC:ai]


systematic_name: M12013
exact_source: GO:0046513
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046513
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid. [GOC:ai]


systematic_name: M10160
exact_source: GO:0046514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid. [GOC:ai]


systematic_name: M12454
exact_source: GO:0046519
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046519
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. [ISBN:0198506732]


systematic_name: M48462
exact_source: GO:0046520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds. [ISBN:0198506732]


systematic_name: M14509
exact_source: GO:0046530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. [GOC:ai, ISBN:0198506732]


systematic_name: M45157
exact_source: GO:0046533
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046533
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. [GOC:go_curators]


systematic_name: M23789
exact_source: GO:0046541
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046541
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. [GOC:curators, UBERON:0001836]


systematic_name: M23790
exact_source: GO:0046543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion. [GOC:ai]


systematic_name: M23791
exact_source: GO:0046545
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046545
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. [GOC:ai]


systematic_name: M23792
exact_source: GO:0046548
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046548
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. [ISBN:0198506732]


systematic_name: M46814
exact_source: GO:0046549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. [ISBN:0198506732]


systematic_name: M8141
exact_source: GO:0046578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of Ras protein signal transduction. [GOC:bf]


systematic_name: M48463
exact_source: GO:0046579
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046579
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction. [GOC:bf]


systematic_name: M48464
exact_source: GO:0046580
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046580
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction. [GOC:bf]


systematic_name: M14436
exact_source: GO:0046597
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046597
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell. [GOC:jl]


systematic_name: M11992
exact_source: GO:0046599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole. [GOC:ai]


systematic_name: M23794
exact_source: GO:0046600
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046600
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication. [GOC:ai]


systematic_name: M23795
exact_source: GO:0046601
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046601
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of centriole replication. [GOC:ai]


systematic_name: M23796
exact_source: GO:0046602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis. [GOC:ai]


systematic_name: M13491
exact_source: GO:0046605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation. [GOC:ai]


systematic_name: M42829
exact_source: GO:0046618
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046618
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a xenobiotic from a cell, into the extracellular region. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc]


systematic_name: M12853
exact_source: GO:0046620
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046620
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of growth of an organ of an organism. [GOC:bf, GOC:tb]


systematic_name: M12014
exact_source: GO:0046621
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046621
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. [GOC:bf, GOC:tb]


systematic_name: M16165
exact_source: GO:0046622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. [GOC:bf, GOC:tb]


systematic_name: M23799
exact_source: GO:0046629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:add]


systematic_name: M14300
exact_source: GO:0046631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:add]


systematic_name: M10942
exact_source: GO:0046632
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046632
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex. [CL:0000789, GOC:ai]


systematic_name: M16840
exact_source: GO:0046635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation. [GOC:ai]


systematic_name: M15072
exact_source: GO:0046636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation. [GOC:ai]


systematic_name: M13365
exact_source: GO:0046637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation. [GOC:ai]


systematic_name: M15528
exact_source: GO:0046638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation. [GOC:ai]


systematic_name: M15480
exact_source: GO:0046639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation. [GOC:ai]


systematic_name: M13471
exact_source: GO:0046641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation. [GOC:ai]


systematic_name: M23801
exact_source: GO:0046642
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046642
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation. [GOC:ai]


systematic_name: M23803
exact_source: GO:0046645
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046645
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation. [GOC:ai]


systematic_name: M2297
exact_source: GO:0046649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M13150
exact_source: GO:0046653
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046653
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. [ISBN:0198506732]


systematic_name: M23804
exact_source: GO:0046654
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046654
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. [ISBN:0198506732]


systematic_name: M16344
exact_source: GO:0046655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. [ISBN:0198506732]


systematic_name: M15489
exact_source: GO:0046677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. [GOC:ai, GOC:ef]


systematic_name: M45158
exact_source: GO:0046683
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046683
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors. [ISBN:0721662544]


systematic_name: M14803
exact_source: GO:0046685
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046685
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. [GOC:hjd, ISBN:0721662544]


systematic_name: M15781
exact_source: GO:0046686
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046686
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. [GOC:ai]


systematic_name: M11424
exact_source: GO:0046688
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046688
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. [GOC:ai]


systematic_name: M15754
exact_source: GO:0046689
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046689
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus. [GOC:ai]


systematic_name: M12009
exact_source: GO:0046697
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046697
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta. [ISBN:0721662544, PMID:11133685]


systematic_name: M14949
exact_source: GO:0046716
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046716
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. [GOC:mah, PMID:3091429, PMID:7781901]


systematic_name: M42831
exact_source: GO:0046753
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046753
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The exit of a viral particle from a host cell that does not involve cell lysis. [GOC:bf, GOC:jl, ISBN:0072370319]


systematic_name: M23806
exact_source: GO:0046755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space. [ISBN:0781718325, VZ:1947]


systematic_name: M16011
exact_source: GO:0046777
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046777
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). [ISBN:0198506732]


systematic_name: M14372
exact_source: GO:0046782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the transcription of the viral genome. [GOC:ai]


systematic_name: M16607
exact_source: GO:0046785
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046785
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of tubulin heterodimers to one or both ends of a microtubule. [GOC:ai, GOC:go_curators]


systematic_name: M23808
exact_source: GO:0046813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface. [ISBN:0879694971]


systematic_name: M12698
exact_source: GO:0046822
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046822
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. [GOC:bf]


systematic_name: M13384
exact_source: GO:0046823
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046823
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. [GOC:bf]


systematic_name: M13934
exact_source: GO:0046824
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046824
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. [GOC:bf]


systematic_name: M11196
exact_source: GO:0046825
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046825
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. [GOC:bf]


systematic_name: M23809
exact_source: GO:0046826
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046826
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. [GOC:bf]


systematic_name: M15643
exact_source: GO:0046827
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046827
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. [GOC:bf]


systematic_name: M34195
exact_source: GO:0046831
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046831
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. [GOC:bf]


systematic_name: M42833
exact_source: GO:0046833
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046833
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm. [GOC:bf]


systematic_name: M14497
exact_source: GO:0046834
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046834
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. [GOC:bf, ISBN:0198506732]


systematic_name: M11297
exact_source: GO:0046835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y. [ISBN:0198506732]


systematic_name: M23810
exact_source: GO:0046836
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046836
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M10903
exact_source: GO:0046839
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046839
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents. [ISBN:0198506732]


systematic_name: M16674
exact_source: GO:0046847
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046847
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. [GOC:dph, GOC:mah, GOC:tb, PMID:16337369, PMID:18464790]


systematic_name: M2217
exact_source: GO:0046849
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046849
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. [GOC:curators]


systematic_name: M13521
exact_source: GO:0046850
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046850
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. [GOC:ai]


systematic_name: M42834
exact_source: GO:0046851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. [GOC:ai]


systematic_name: M23812
exact_source: GO:0046854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. [ISBN:0198506732]


systematic_name: M45159
exact_source: GO:0046864
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046864
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. [GOC:ai]


systematic_name: M29219
exact_source: GO:0046874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid. [GOC:ai]


systematic_name: M23813
exact_source: GO:0046877
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046877
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. [GOC:ai]


systematic_name: M16778
exact_source: GO:0046883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. [GOC:ai]


systematic_name: M23814
exact_source: GO:0046884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. [ISBN:0198506732]


systematic_name: M13824
exact_source: GO:0046885
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046885
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. [GOC:ai]


systematic_name: M23815
exact_source: GO:0046886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. [GOC:ai]


systematic_name: M13625
exact_source: GO:0046887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. [GOC:ai]


systematic_name: M14459
exact_source: GO:0046888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. [GOC:ai]


systematic_name: M15494
exact_source: GO:0046889
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046889
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. [GOC:ai]


systematic_name: M12119
exact_source: GO:0046890
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046890
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. [GOC:ai]


systematic_name: M48465
exact_source: GO:0046898
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046898
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes. [GOC:ef, ISBN:0198506732]


systematic_name: M40453
exact_source: GO:0046902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. [GOC:bf]


systematic_name: M45883
exact_source: GO:0046928
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046928
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. [GOC:ai]


systematic_name: M12855
exact_source: GO:0046929
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046929
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. [GOC:ai]


systematic_name: M13274
exact_source: GO:0046931
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046931
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases. [GOC:jl, GOC:mah]


systematic_name: M23817
exact_source: GO:0046940
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046940
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside. [GOC:ai]


systematic_name: M23818
exact_source: GO:0046949
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046949
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. [ISBN:0198506732]


systematic_name: M23820
exact_source: GO:0046951
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046951
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. [ISBN:0198506732]


systematic_name: M48466
exact_source: GO:0046958
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046958
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment. [ISBN:0582227089]


systematic_name: M48467
exact_source: GO:0046967
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046967
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell. [GOC:ai]


systematic_name: M40455
exact_source: GO:0046984
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046984
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. [GOC:ai]


systematic_name: M45884
exact_source: GO:0046985
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0046985
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin. [GOC:ai]


systematic_name: M34196
exact_source: GO:0047496
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0047496
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. [GOC:ecd, GOC:rl]


systematic_name: M11444
exact_source: GO:0048002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein. [GOC:add, ISBN:0781735149, PMID:15771591]


systematic_name: M23823
exact_source: GO:0048003
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048003
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. [GOC:add, PMID:10375559, PMID:15928678, PMID:15928680]


systematic_name: M23824
exact_source: GO:0048006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family. [GOC:add, PMID:10375559, PMID:15928678, PMID:15928680]


systematic_name: M10050
exact_source: GO:0048008
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048008
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]


systematic_name: M12608
exact_source: GO:0048009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to an insulin-like growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]


systematic_name: M11150
exact_source: GO:0048010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb, GOC:signaling]


systematic_name: M15971
exact_source: GO:0048011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:ceb, GOC:jc, GOC:signaling, PMID:12065629, Wikipedia:Trk_receptor]


systematic_name: M23825
exact_source: GO:0048012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a hepatocyte growth factor receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]


systematic_name: M13554
exact_source: GO:0048013
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048013
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]


systematic_name: M4611
exact_source: GO:0048015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. [GOC:bf, GOC:ceb, ISBN:0198506732]


systematic_name: M14810
exact_source: GO:0048024
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048024
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism. [GOC:jid]


systematic_name: M10965
exact_source: GO:0048041
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048041
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. [GOC:jid, GOC:mah]


systematic_name: M15167
exact_source: GO:0048048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. [GOC:jid]


systematic_name: M23827
exact_source: GO:0048050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight. [GOC:jid, GOC:sensu]


systematic_name: M14311
exact_source: GO:0048066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. [ISBN:0582227089]


systematic_name: M23829
exact_source: GO:0048087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. [GOC:dph, GOC:jid, GOC:tb]


systematic_name: M23831
exact_source: GO:0048102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. [GOC:autophagy, GOC:mah, GOC:mtg_apoptosis, PMID:18846107, PMID:23347517]


systematic_name: M14798
exact_source: GO:0048103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. [GOC:jid, ISBN:0582227089]


systematic_name: M23832
exact_source: GO:0048143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, PMID:10526094, PMID:10695728, PMID:12529254, PMID:12580336, PMID:9585813]


systematic_name: M23833
exact_source: GO:0048144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. [GOC:jid]


systematic_name: M45160
exact_source: GO:0048145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. [GOC:jid]


systematic_name: M10907
exact_source: GO:0048146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. [GOC:jid]


systematic_name: M11687
exact_source: GO:0048147
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048147
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. [GOC:jid]


systematic_name: M14731
exact_source: GO:0048148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus. [GOC:jid]


systematic_name: M23834
exact_source: GO:0048149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus. [GOC:jid]


systematic_name: M45885
exact_source: GO:0048165
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048165
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. [GOC:jid, GOC:mtg_sensu, ISBN:0198542771]


systematic_name: M12474
exact_source: GO:0048167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. [GOC:dph, GOC:jid, GOC:tb, PMID:11891290]


systematic_name: M10720
exact_source: GO:0048168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. [GOC:jid, PMID:11891290]


systematic_name: M14794
exact_source: GO:0048169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. [GOC:jid, PMID:11891290]


systematic_name: M23835
exact_source: GO:0048170
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048170
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers. [GOC:jid, PMID:11891290]


systematic_name: M11095
exact_source: GO:0048172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity. [GOC:jid, PMID:11891290]


systematic_name: M18265
exact_source: GO:0048193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. [GOC:jid, ISBN:0716731363, PMID:10219233]


systematic_name: M23836
exact_source: GO:0048194
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048194
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The evagination of the Golgi membrane, resulting in formation of a vesicle. [GOC:jid, ISBN:0716731363, PMID:10219233]


systematic_name: M23837
exact_source: GO:0048199
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048199
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233]


systematic_name: M42836
exact_source: GO:0048207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi. [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233]


systematic_name: M11476
exact_source: GO:0048232
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048232
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. [GOC:dph, GOC:jid]


systematic_name: M11985
exact_source: GO:0048240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818]


systematic_name: M23840
exact_source: GO:0048241
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048241
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:jid]


systematic_name: M48468
exact_source: GO:0048242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system. [GOC:ef, GOC:jid]


systematic_name: M48469
exact_source: GO:0048243
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048243
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. [GOC:ef, GOC:jid]


systematic_name: M14280
exact_source: GO:0048247
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048247
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a lymphocyte in response to an external stimulus. [GOC:hjd, GOC:jid, PMID:12391252]


systematic_name: M23843
exact_source: GO:0048251
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048251
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. [GOC:jid, PMID:10841810, PMID:12615674]


systematic_name: M23844
exact_source: GO:0048254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which small nucleolar RNA is transported to, or maintained in, a specific location. [ISBN:0716731363]


systematic_name: M12909
exact_source: GO:0048259
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048259
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. [GOC:go_curators, GOC:tb]


systematic_name: M11511
exact_source: GO:0048260
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048260
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. [GOC:go_curators, GOC:tb]


systematic_name: M15867
exact_source: GO:0048261
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048261
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport. [GOC:go_curators]


systematic_name: M23845
exact_source: GO:0048262
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048262
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis. [GOC:jid]


systematic_name: M12693
exact_source: GO:0048265
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048265
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. [GOC:jid, PMID:10203867, PMID:12723742, PMID:12843304, Wikipedia:Pain]


systematic_name: M12655
exact_source: GO:0048266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. [GOC:jid]


systematic_name: M11401
exact_source: GO:0048268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage. [GOC:jid, PMID:11460887, PMID:11977118, PMID:9531549]


systematic_name: M15765
exact_source: GO:0048278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. [GOC:ai, GOC:jid]


systematic_name: M23846
exact_source: GO:0048280
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048280
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. [GOC:jid]


systematic_name: M16792
exact_source: GO:0048286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. [GOC:mtg_lung, PMID:9751757]


systematic_name: M23847
exact_source: GO:0048290
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048290
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus. [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655]


systematic_name: M23848
exact_source: GO:0048291
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048291
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. [ISBN:0781735149, PMID:12370374, PMID:2113175, PMID:9186655]


systematic_name: M23849
exact_source: GO:0048293
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048293
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes. [GOC:jid]


systematic_name: M23851
exact_source: GO:0048304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes. [GOC:jid]


systematic_name: M16115
exact_source: GO:0048311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that establishes the spatial arrangement of mitochondria between and within cells. [GOC:jid]


systematic_name: M23854
exact_source: GO:0048318
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048318
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. [GOC:dgh]


systematic_name: M13650
exact_source: GO:0048332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the mesoderm are generated and organized. [GOC:go_curators]


systematic_name: M14281
exact_source: GO:0048333
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048333
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. [GOC:dgh]


systematic_name: M15054
exact_source: GO:0048339
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048339
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. [GOC:dgh]


systematic_name: M23855
exact_source: GO:0048340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the paraxial mesoderm are generated and organized. [GOC:go_curators]


systematic_name: M23856
exact_source: GO:0048341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. [GOC:dgh]


systematic_name: M12169
exact_source: GO:0048368
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048368
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. [GOC:go_curators]


systematic_name: M48470
exact_source: GO:0048369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the lateral mesoderm are generated and organized. [GOC:go_curators]


systematic_name: M23857
exact_source: GO:0048382
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048382
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues. [GOC:jid]


systematic_name: M16403
exact_source: GO:0048384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands. [GOC:dgh]


systematic_name: M11133
exact_source: GO:0048385
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048385
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity. [GOC:dgh]


systematic_name: M34197
exact_source: GO:0048386
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048386
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity. [GOC:dgh]


systematic_name: M12503
exact_source: GO:0048387
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048387
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity. [GOC:dgh]


systematic_name: M42838
exact_source: GO:0048388
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048388
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion. [GOC:jid]


systematic_name: M12957
exact_source: GO:0048469
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048469
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state. [GOC:go_curators]


systematic_name: M11093
exact_source: GO:0048477
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048477
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. [GOC:kmv, GOC:mtg_sensu, GOC:pr]


systematic_name: M15038
exact_source: GO:0048483
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048483
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. [FMA:9905, GOC:jid, GOC:sr]


systematic_name: M14613
exact_source: GO:0048484
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048484
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. [FMA:66070, GOC:jid, GOC:sr]


systematic_name: M13364
exact_source: GO:0048485
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048485
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. [FMA:9906, GOC:jid, GOC:sr]


systematic_name: M16085
exact_source: GO:0048486
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048486
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. [FMA:9907, GOC:jid, GOC:sr]


systematic_name: M23859
exact_source: GO:0048496
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048496
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized. [GOC:tb]


systematic_name: M42839
exact_source: GO:0048499
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048499
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle. [GOC:dph, GOC:jl, GOC:mah, PMID:10620806]


systematic_name: M18740
exact_source: GO:0048511
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048511
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. [GOC:jid]


systematic_name: M13415
exact_source: GO:0048514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. [GOC:jid]


systematic_name: M6833
exact_source: GO:0048515
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048515
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:dph, GOC:jid]


systematic_name: M11391
exact_source: GO:0048520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. [GOC:jid, GOC:pr]


systematic_name: M13816
exact_source: GO:0048521
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048521
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. [GOC:jid, GOC:pr]


systematic_name: M16056
exact_source: GO:0048524
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048524
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant. [GOC:bf, GOC:jl]


systematic_name: M10974
exact_source: GO:0048525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant. [GOC:bf, GOC:jl]


systematic_name: M11732
exact_source: GO:0048532
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048532
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [GOC:go_curators]


systematic_name: M13225
exact_source: GO:0048534
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048534
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. [GOC:add, GOC:rl, ISBN:0781735149]


systematic_name: M11111
exact_source: GO:0048535
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048535
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. [GOC:add, ISBN:068340007X, ISBN:0781735149]


systematic_name: M16796
exact_source: GO:0048536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. [GOC:add, ISBN:0781735149]


systematic_name: M23860
exact_source: GO:0048537
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048537
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. [GOC:add, ISBN:0781735149]


systematic_name: M11220
exact_source: GO:0048538
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048538
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. [GOC:add, ISBN:0781735149]


systematic_name: M23861
exact_source: GO:0048539
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048539
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. [GOC:add, ISBN:0781735149]


systematic_name: M13901
exact_source: GO:0048545
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048545
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. [GOC:go_curators]


systematic_name: M13216
exact_source: GO:0048546
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048546
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. [GOC:dph, GOC:go_curators, PMID:12618131]


systematic_name: M23862
exact_source: GO:0048548
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048548
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. [GOC:go_curators]


systematic_name: M23863
exact_source: GO:0048549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. [GOC:go_curators]


systematic_name: M23864
exact_source: GO:0048550
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048550
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes. [GOC:go_curators]


systematic_name: M12122
exact_source: GO:0048557
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048557
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed. [GOC:go_curators]


systematic_name: M12776
exact_source: GO:0048562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:jid]


systematic_name: M12859
exact_source: GO:0048566
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048566
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus. [GOC:go_curators]


systematic_name: M16163
exact_source: GO:0048568
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048568
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:jid]


systematic_name: M23867
exact_source: GO:0048570
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048570
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. [GOC:jid]


systematic_name: M7398
exact_source: GO:0048585
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048585
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]


systematic_name: M14996
exact_source: GO:0048588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. [GOC:go_curators, GOC:isa_complete]


systematic_name: M18572
exact_source: GO:0048589
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048589
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. [GOC:go_curators]


systematic_name: M16960
exact_source: GO:0048592
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048592
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the eye are generated and organized. [GOC:jid, GOC:mtg_sensu]


systematic_name: M15968
exact_source: GO:0048593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. [GOC:jid, GOC:mtg_sensu]


systematic_name: M12711
exact_source: GO:0048596
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048596
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the eye are generated and organized during embryonic development. [GOC:jid, GOC:mtg_sensu]


systematic_name: M18144
exact_source: GO:0048598
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048598
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. [GOC:jid, GOC:mtg_sensu]


systematic_name: M48471
exact_source: GO:0048609
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048609
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. [GOC:dph, GOC:jid, GOC:tb]


systematic_name: M23868
exact_source: GO:0048625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:dph, GOC:mtg_muscle]


systematic_name: M23869
exact_source: GO:0048630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. [GOC:lm, PMID:15726494, PMID:15907921]


systematic_name: M23870
exact_source: GO:0048631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle growth. [GOC:lm, PMID:15726494, PMID:15907921]


systematic_name: M40456
exact_source: GO:0048633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of skeletal muscle growth. [GOC:lm, PMID:15726494, PMID:15907921]


systematic_name: M40457
exact_source: GO:0048635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. [GOC:go_curators]


systematic_name: M13900
exact_source: GO:0048639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of developmental growth. [GOC:go_curators]


systematic_name: M11940
exact_source: GO:0048640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. [GOC:go_curators]


systematic_name: M10364
exact_source: GO:0048641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. [GOC:go_curators]


systematic_name: M10499
exact_source: GO:0048643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of skeletal muscle tissue development. [GOC:go_curators]


systematic_name: M23872
exact_source: GO:0048645
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048645
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. [GOC:dph, GOC:jid]


systematic_name: M8071
exact_source: GO:0048646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [GOC:dph, GOC:jid, GOC:tb]


systematic_name: M23873
exact_source: GO:0048659
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048659
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. [CL:0000192, GOC:ebc, PMID:1840698]


systematic_name: M12472
exact_source: GO:0048661
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048661
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of smooth muscle cell proliferation. [CL:0000192, GOC:ebc]


systematic_name: M10483
exact_source: GO:0048662
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048662
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. [CL:0000192, GOC:ebc]


systematic_name: M15345
exact_source: GO:0048663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron. [GOC:dph]


systematic_name: M23874
exact_source: GO:0048664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed. [GOC:dph]


systematic_name: M13126
exact_source: GO:0048665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. [GOC:dph]


systematic_name: M6784
exact_source: GO:0048666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:dph]


systematic_name: M46815
exact_source: GO:0048667
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048667
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. [GOC:dph, GOC:tb]


systematic_name: M23875
exact_source: GO:0048668
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048668
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which outgrowths develop from the shafts of existing axons. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M23876
exact_source: GO:0048669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which outgrowths develop from the axons of intact undamaged neurons. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M10321
exact_source: GO:0048670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of collateral sprouting. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M23877
exact_source: GO:0048671
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048671
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M23878
exact_source: GO:0048672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of collateral sprouting. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M16466
exact_source: GO:0048675
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048675
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Long distance growth of a single axon process involved in cellular development. [GOC:BHF, GOC:dgh, GOC:dph, GOC:jid, GOC:lm, GOC:rl]


systematic_name: M11430
exact_source: GO:0048678
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048678
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. [GOC:dgh, GOC:dph, GOC:jid, GOC:lm]


systematic_name: M4258
exact_source: GO:0048699
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048699
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. [GOC:nln]


systematic_name: M16821
exact_source: GO:0048701
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048701
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase. [GOC:dsf, GOC:jid, PMID:16049113]


systematic_name: M23879
exact_source: GO:0048702
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048702
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain. [GOC:dsf, GOC:jid, PMID:16049113]


systematic_name: M12022
exact_source: GO:0048703
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048703
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones. [GOC:dsf, GOC:jid, PMID:16049113]


systematic_name: M10927
exact_source: GO:0048704
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048704
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase. [GOC:dph, GOC:dsf, GOC:jid, GOC:tb, PMID:16049113]


systematic_name: M16413
exact_source: GO:0048705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the skeleton are generated and organized. [GOC:dph, GOC:dsf, GOC:jid, GOC:tb]


systematic_name: M10808
exact_source: GO:0048706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. [GOC:dph, GOC:dsf, GOC:jid, GOC:tb, PMID:16049113]


systematic_name: M13469
exact_source: GO:0048708
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048708
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. [GOC:vp, PMID:15139015]


systematic_name: M15768
exact_source: GO:0048709
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048709
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. [GOC:vp, PMID:15139015]


systematic_name: M11897
exact_source: GO:0048710
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048710
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of astrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M16412
exact_source: GO:0048711
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048711
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M11852
exact_source: GO:0048712
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048712
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M13568
exact_source: GO:0048713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M12296
exact_source: GO:0048714
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048714
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M10523
exact_source: GO:0048715
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048715
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. [GOC:vp, PMID:15139015]


systematic_name: M16103
exact_source: GO:0048729
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048729
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a tissue are generated and organized. [GOC:dph, GOC:jid]


systematic_name: M10383
exact_source: GO:0048730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. [GOC:jid, UBERON:0001003]


systematic_name: M2173
exact_source: GO:0048732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. [GOC:jid]


systematic_name: M23880
exact_source: GO:0048733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. [GOC:jid]


systematic_name: M13260
exact_source: GO:0048736
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048736
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. [GOC:jid, GOC:rc]


systematic_name: M23882
exact_source: GO:0048742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm]


systematic_name: M23883
exact_source: GO:0048743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle]


systematic_name: M12415
exact_source: GO:0048745
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048745
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. [GOC:dph, GOC:jid, GOC:lm]


systematic_name: M42840
exact_source: GO:0048752
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048752
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the semicircular canals are generated and organized. [GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M13670
exact_source: GO:0048753
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048753
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. [GOC:rc]


systematic_name: M16051
exact_source: GO:0048754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. [GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M23885
exact_source: GO:0048755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). [GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M23886
exact_source: GO:0048757
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048757
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state. [GOC:dgh, GOC:jid, GOC:mh]


systematic_name: M12556
exact_source: GO:0048762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. [GOC:dph, GOC:jid]


systematic_name: M19176
exact_source: GO:0048771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. [GOC:ebc]


systematic_name: M23887
exact_source: GO:0048790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters. [GOC:curators, GOC:dph, GOC:pr]


systematic_name: M13690
exact_source: GO:0048791
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048791
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels. [GOC:curators]


systematic_name: M23888
exact_source: GO:0048793
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048793
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151]


systematic_name: M23889
exact_source: GO:0048799
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048799
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. [GOC:curators]


systematic_name: M15894
exact_source: GO:0048806
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048806
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. [GOC:jid]


systematic_name: M12944
exact_source: GO:0048813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a dendrite are generated and organized. [GOC:aruk, GOC:bc, GOC:jl, ISBN:0198506732, PMID:22683681]


systematic_name: M42841
exact_source: GO:0048818
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048818
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of hair follicle maturation. [GOC:devbiol]


systematic_name: M23891
exact_source: GO:0048820
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048820
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. [GOC:devbiol]


systematic_name: M16510
exact_source: GO:0048821
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048821
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. [GOC:devbiol]


systematic_name: M48472
exact_source: GO:0048822
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048822
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:devbiol]


systematic_name: M23892
exact_source: GO:0048840
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048840
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure. [GOC:sr]


systematic_name: M48473
exact_source: GO:0048841
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048841
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance. [GOC:devbiol]


systematic_name: M40458
exact_source: GO:0048842
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048842
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance. [GOC:devbiol]


systematic_name: M40459
exact_source: GO:0048843
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048843
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance. [GOC:devbiol]


systematic_name: M12492
exact_source: GO:0048844
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048844
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. [GOC:dsf, PMID:16740480]


systematic_name: M23893
exact_source: GO:0048845
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048845
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. [GOC:dsf, PMID:16740480]


systematic_name: M10585
exact_source: GO:0048853
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048853
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M16971
exact_source: GO:0048854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). [GOC:dgh, GOC:jid]


systematic_name: M12662
exact_source: GO:0048857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. [GO_REF:0000021]


systematic_name: M48474
exact_source: GO:0048858
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048858
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a cell projection are generated and organized. [GO_REF:0000021]


systematic_name: M42842
exact_source: GO:0048859
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048859
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [GO_REF:0000021]


systematic_name: M15304
exact_source: GO:0048863
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048863
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [CL:0000034, GOC:isa_complete]


systematic_name: M45161
exact_source: GO:0048864
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048864
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. [CL:0000034, GOC:isa_complete]


systematic_name: M23895
exact_source: GO:0048865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell. [CL:0000034, GOC:isa_complete]


systematic_name: M45162
exact_source: GO:0048866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. [CL:0000034, GOC:isa_complete]


systematic_name: M45163
exact_source: GO:0048870
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048870
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg]


systematic_name: M14669
exact_source: GO:0048871
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048871
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. [GOC:isa_complete]


systematic_name: M18350
exact_source: GO:0048872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. [GOC:isa_complete]


systematic_name: M14873
exact_source: GO:0048873
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048873
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. [GOC:isa_complete]


systematic_name: M45164
exact_source: GO:0048874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut. [PMID:25757720]


systematic_name: M17520
exact_source: GO:0048878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of an internal steady state of a chemical. [GOC:isa_complete]


systematic_name: M23896
exact_source: GO:0048880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. [GOC:dgh]


systematic_name: M12811
exact_source: GO:0048934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0048934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. [GOC:dgh]


systematic_name: M10919
exact_source: GO:0050000
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050000
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a chromosome is transported to, or maintained in, a specific location. [GOC:ai]


systematic_name: M23897
exact_source: GO:0050427
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050427
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems. [ISBN:0198506732]


systematic_name: M23899
exact_source: GO:0050432
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050432
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. [GOC:ai, GOC:ef]


systematic_name: M23900
exact_source: GO:0050435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP). [GOC:ai]


systematic_name: M12097
exact_source: GO:0050650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. [GOC:ai]


systematic_name: M45887
exact_source: GO:0050651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. [GOC:ai]


systematic_name: M15611
exact_source: GO:0050654
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0050654
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. [GOC:ai]


