# gene_set_details

systematic_name: M22665
exact_source: GO:0010737
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010737
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C. [PMID:35252178, PMID:36431013]


systematic_name: M13147
exact_source: GO:0010738
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010738
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22666
exact_source: GO:0010739
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010739
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12121
exact_source: GO:0010743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M11590
exact_source: GO:0010744
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010744
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:dph, GOC:tb]


systematic_name: M14235
exact_source: GO:0010745
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010745
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M34091
exact_source: GO:0010746
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010746
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22667
exact_source: GO:0010749
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010749
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO). [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22669
exact_source: GO:0010752
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010752
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22670
exact_source: GO:0010753
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010753
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of cGMP-mediated signaling. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22671
exact_source: GO:0010754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22672
exact_source: GO:0010755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22673
exact_source: GO:0010756
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010756
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22674
exact_source: GO:0010757
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010757
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12468
exact_source: GO:0010758
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010758
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M13699
exact_source: GO:0010759
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010759
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22675
exact_source: GO:0010760
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010760
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22676
exact_source: GO:0010761
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010761
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M11312
exact_source: GO:0010762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. [GOC:dph, GOC:tb]


systematic_name: M11477
exact_source: GO:0010763
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010763
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22677
exact_source: GO:0010764
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010764
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. [GOC:dph, GOC:tb]


systematic_name: M11460
exact_source: GO:0010765
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010765
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


systematic_name: M10528
exact_source: GO:0010766
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010766
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


systematic_name: M46740
exact_source: GO:0010770
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010770
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. [GOC:dph, GOC:tb]


systematic_name: M40377
exact_source: GO:0010793
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010793
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm. [GOC:dph, GOC:tb]


systematic_name: M14821
exact_source: GO:0010799
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010799
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. [GOC:dph, GOC:tb]


systematic_name: M13887
exact_source: GO:0010800
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010800
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. [GOC:dph, GOC:tb]


systematic_name: M13269
exact_source: GO:0010801
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010801
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine. [GOC:dph, GOC:tb]


systematic_name: M14642
exact_source: GO:0010803
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010803
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. [GOC:dph, GOC:tb]


systematic_name: M11436
exact_source: GO:0010804
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010804
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. [GOC:dph, GOC:tb]


systematic_name: M22680
exact_source: GO:0010807
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010807
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion. [GOC:dph, GOC:kmv, GOC:tb, PMID:15489511]


systematic_name: M14273
exact_source: GO:0010810
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010810
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. [GOC:dph, GOC:pf, GOC:tb]


systematic_name: M16144
exact_source: GO:0010811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. [GOC:dph, GOC:pf, GOC:tb]


systematic_name: M12057
exact_source: GO:0010812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules. [GOC:dph, GOC:pf, GOC:tb]


systematic_name: M22681
exact_source: GO:0010815
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010815
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin. [GOC:BHF, GOC:rl]


systematic_name: M11178
exact_source: GO:0010817
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010817
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22682
exact_source: GO:0010818
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010818
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. [GOC:dph, GOC:tb]


systematic_name: M10473
exact_source: GO:0010819
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010819
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. [GOC:dph, GOC:tb]


systematic_name: M12250
exact_source: GO:0010821
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010821
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. [GOC:dph, GOC:tb]


systematic_name: M40378
exact_source: GO:0010826
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010826
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. [GOC:dph, GOC:tb]


systematic_name: M22684
exact_source: GO:0010827
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010827
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


systematic_name: M22685
exact_source: GO:0010828
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010828
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22686
exact_source: GO:0010829
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010829
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M14489
exact_source: GO:0010830
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010830
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:dph, GOC:tb]


systematic_name: M10106
exact_source: GO:0010831
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010831
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:dph, GOC:tb]


systematic_name: M11295
exact_source: GO:0010832
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010832
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:dph, GOC:tb]


systematic_name: M11252
exact_source: GO:0010833
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010833
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. [GOC:dph, GOC:tb]


systematic_name: M22687
exact_source: GO:0010835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids. [GOC:dph, GOC:tb]


systematic_name: M13117
exact_source: GO:0010837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. [GOC:dph, GOC:tb]


systematic_name: M22688
exact_source: GO:0010838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. [GOC:dph, GOC:tb]


systematic_name: M16775
exact_source: GO:0010839
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010839
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. [GOC:dph, GOC:tb]


systematic_name: M14064
exact_source: GO:0010842
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010842
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266]


systematic_name: M15739
exact_source: GO:0010866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. [GOC:BHF, GOC:tb]


systematic_name: M13622
exact_source: GO:0010867
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010867
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. [GOC:BHF, GOC:tb]


systematic_name: M42666
exact_source: GO:0010868
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010868
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol. [GOC:BHF, GOC:tb]


systematic_name: M11164
exact_source: GO:0010874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M11122
exact_source: GO:0010875
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010875
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M15749
exact_source: GO:0010876
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010876
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a lipid is transported to, or maintained in, a specific location. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22693
exact_source: GO:0010878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M46741
exact_source: GO:0010880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M11807
exact_source: GO:0010881
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010881
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12792
exact_source: GO:0010882
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010882
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M10255
exact_source: GO:0010883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M15691
exact_source: GO:0010884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M46742
exact_source: GO:0010885
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010885
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22694
exact_source: GO:0010886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22695
exact_source: GO:0010887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M14609
exact_source: GO:0010888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12066
exact_source: GO:0010889
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010889
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22696
exact_source: GO:0010890
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010890
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22697
exact_source: GO:0010891
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010891
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M13082
exact_source: GO:0010896
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010896
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. [GOC:rn, GOC:tb]


systematic_name: M29098
exact_source: GO:0010897
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010897
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. [GOC:rn, GOC:tb]


systematic_name: M22698
exact_source: GO:0010898
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010898
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride. [GOC:rn, GOC:tb]


systematic_name: M22699
exact_source: GO:0010901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid. [GOC:tb]


systematic_name: M13722
exact_source: GO:0010906
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010906
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. [GOC:BHF, GOC:tb]


systematic_name: M16946
exact_source: GO:0010907
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010907
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. [GOC:BHF, GOC:tb]


systematic_name: M22700
exact_source: GO:0010911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5. [GOC:dph, GOC:tb]


systematic_name: M22701
exact_source: GO:0010915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22702
exact_source: GO:0010918
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010918
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:dph, GOC:tb]


systematic_name: M13682
exact_source: GO:0010919
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010919
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M10601
exact_source: GO:0010921
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010921
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing phosphate. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M16598
exact_source: GO:0010922
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010922
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M42667
exact_source: GO:0010923
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010923
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12564
exact_source: GO:0010927
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010927
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular component assembly that is part of the initial shaping of the component during its developmental progression. [GOC:dph, GOC:tb]


systematic_name: M22703
exact_source: GO:0010934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


systematic_name: M22704
exact_source: GO:0010936
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010936
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF, GOC:rl]


systematic_name: M22706
exact_source: GO:0010944
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010944
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site. [GOC:tb]


systematic_name: M12573
exact_source: GO:0010948
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010948
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [GOC:dph, GOC:tb]


systematic_name: M13564
exact_source: GO:0010952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]


systematic_name: M22707
exact_source: GO:0010957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22709
exact_source: GO:0010960
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010960
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. [GOC:dph, GOC:tb]


systematic_name: M48382
exact_source: GO:0010961
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010961
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell. [GOC:dph, GOC:tb]


systematic_name: M22711
exact_source: GO:0010966
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010966
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


systematic_name: M22712
exact_source: GO:0010968
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010968
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. [GOC:dph, GOC:tb]


systematic_name: M14533
exact_source: GO:0010975
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010975
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


systematic_name: M16634
exact_source: GO:0010976
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010976
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


systematic_name: M22713
exact_source: GO:0010977
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010977
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). [GOC:dph, GOC:tb]


systematic_name: M22714
exact_source: GO:0010982
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010982
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M45821
exact_source: GO:0010983
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010983
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M15875
exact_source: GO:0010984
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010984
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22715
exact_source: GO:0010985
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010985
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22716
exact_source: GO:0010986
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010986
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22717
exact_source: GO:0010988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22718
exact_source: GO:0010989
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010989
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22721
exact_source: GO:0010992
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010992
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates. [GOC:BHF, GOC:dph, GOC:tb, PMID:19410548]


systematic_name: M22722
exact_source: GO:0010994
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010994
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M13797
exact_source: GO:0010996
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010996
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus. [GOC:BHF, GOC:dph, GOC:sl, GOC:tb]


systematic_name: M22723
exact_source: GO:0010998
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010998
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha. [GOC:BHF, GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M16698
exact_source: GO:0014002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. [GOC:dgh, GOC:ef]


systematic_name: M15263
exact_source: GO:0014003
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014003
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. [GOC:dgh, GOC:ef]


systematic_name: M22724
exact_source: GO:0014004
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014004
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. [GOC:ef]


systematic_name: M22725
exact_source: GO:0014009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. [GOC:ef, ISBN:0878932585]


systematic_name: M22726
exact_source: GO:0014010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. [GOC:ef, ISBN:0878932585]


systematic_name: M22727
exact_source: GO:0014012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury. [GOC:ef]


systematic_name: M16014
exact_source: GO:0014013
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014013
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. [GOC:ef]


systematic_name: M10717
exact_source: GO:0014014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. [GOC:ef]


systematic_name: M16883
exact_source: GO:0014015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. [GOC:ef]


systematic_name: M34095
exact_source: GO:0014016
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014016
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. [GOC:ef, ISBN:0878932585]


systematic_name: M22728
exact_source: GO:0014029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. [GOC:dh, GOC:ef]


systematic_name: M42670
exact_source: GO:0014031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. [GOC:dh, GOC:ef]


systematic_name: M16602
exact_source: GO:0014033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. [GOC:dh, GOC:ef]


systematic_name: M15313
exact_source: GO:0014037
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014037
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. [GOC:ef]


systematic_name: M22729
exact_source: GO:0014041
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014041
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. [GOC:ef]


systematic_name: M40380
exact_source: GO:0014046
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014046
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. [GOC:ef]


systematic_name: M10238
exact_source: GO:0014047
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014047
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. [GOC:ef]


systematic_name: M14978
exact_source: GO:0014048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the controlled release of glutamate. [GOC:ef]


systematic_name: M22732
exact_source: GO:0014049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. [GOC:ef]


systematic_name: M22733
exact_source: GO:0014050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. [GOC:ef]


systematic_name: M22734
exact_source: GO:0014051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. [GOC:ef]


systematic_name: M42672
exact_source: GO:0014052
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014052
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. [GOC:ef]


systematic_name: M48383
exact_source: GO:0014059
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014059
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of dopamine. [GOC:ef]


systematic_name: M22736
exact_source: GO:0014062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of serotonin. [GOC:ef]


systematic_name: M13300
exact_source: GO:0014070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. [GOC:ef]


systematic_name: M46744
exact_source: GO:0014072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. [GOC:ef]


systematic_name: M16537
exact_source: GO:0014074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. [GOC:ef]


systematic_name: M10567
exact_source: GO:0014075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. [GOC:ef]


systematic_name: M1772
exact_source: GO:0014706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. [CL:0000737, GOC:dph, GOC:mtg_muscle]


systematic_name: M22738
exact_source: GO:0014719
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014719
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. [GOC:mtg_muscle, PMID:23303905]


systematic_name: M22739
exact_source: GO:0014722
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014722
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction. [GOC:mtg_muscle]


systematic_name: M42673
exact_source: GO:0014732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. [GOC:mtg_muscle]


systematic_name: M14115
exact_source: GO:0014733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. [GOC:mtg_muscle]


systematic_name: M15459
exact_source: GO:0014741
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014741
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. [GOC:mtg_muscle]


systematic_name: M13031
exact_source: GO:0014742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. [GOC:mtg_muscle]


systematic_name: M22740
exact_source: GO:0014744
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014744
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of muscle adaptation. [GOC:mtg_muscle]


systematic_name: M22741
exact_source: GO:0014745
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014745
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. [GOC:mtg_muscle]


systematic_name: M22742
exact_source: GO:0014805
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014805
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. [GOC:mtg_muscle]


systematic_name: M48384
exact_source: GO:0014809
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014809
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction. [GOC:mtg_muscle]


systematic_name: M16216
exact_source: GO:0014812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. [CL:0000187, GOC:mtg_muscle]


systematic_name: M22745
exact_source: GO:0014816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a satellite cell. [GOC:ef, GOC:mtg_muscle, PMID:16607119]


systematic_name: M15469
exact_source: GO:0014819
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014819
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle contraction. [GOC:ef, GOC:mtg_muscle]


systematic_name: M22746
exact_source: GO:0014820
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014820
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction. [GOC:mtg_muscle]


systematic_name: M12983
exact_source: GO:0014821
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014821
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. [GOC:mtg_muscle]


systematic_name: M16849
exact_source: GO:0014823
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014823
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus. [GOC:mtg_muscle]


systematic_name: M22748
exact_source: GO:0014827
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014827
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. [GOC:mtg_muscle, MA:0001539, MSH:D007422]


systematic_name: M13177
exact_source: GO:0014829
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014829
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion. [GOC:mtg_muscle, MA:0002718]


systematic_name: M22749
exact_source: GO:0014831
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014831
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). [GOC:mtg_muscle, MA:0001523, MSH:D041981]


systematic_name: M40381
exact_source: GO:0014832
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014832
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956]


systematic_name: M45086
exact_source: GO:0014834
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014834
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells. [GOC:dph, GOC:ef, GOC:mtg_muscle, GOC:tb, PMID:23303905]


systematic_name: M45087
exact_source: GO:0014841
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014841
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. [GOC:ef, GOC:mtg_muscle, PMID:16607119]


systematic_name: M46745
exact_source: GO:0014842
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014842
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation. [GOC:ef, GOC:mtg_muscle, PMID:16607119]


systematic_name: M22750
exact_source: GO:0014848
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014848
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551]


systematic_name: M14486
exact_source: GO:0014850
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014850
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. [GOC:mtg_muscle]


systematic_name: M12689
exact_source: GO:0014854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus. [GOC:mtg_muscle]


systematic_name: M14840
exact_source: GO:0014855
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014855
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. [CL:0000737, GOC:ef, GOC:mtg_muscle]


systematic_name: M22751
exact_source: GO:0014856
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014856
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. [CL:0000188, GOC:ef, GOC:mtg_muscle]


systematic_name: M40382
exact_source: GO:0014857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. [CL:0000188, GOC:ef, GOC:mtg_muscle]


systematic_name: M45088
exact_source: GO:0014859
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014859
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. [CL:0000188, GOC:ef, GOC:mtg_muscle]


systematic_name: M22752
exact_source: GO:0014866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. [GOC:ef, GOC:mtg_muscle]


systematic_name: M22753
exact_source: GO:0014870
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014870
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. [GOC:mtg_muscle]


systematic_name: M14388
exact_source: GO:0014874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. [GOC:ef, GOC:mtg_muscle]


systematic_name: M22754
exact_source: GO:0014883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation. [GOC:ef, GOC:mtg_muscle]


systematic_name: M16049
exact_source: GO:0014888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. [GOC:mtg_muscle]


systematic_name: M13975
exact_source: GO:0014889
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014889
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. [GOC:mtg_muscle]


systematic_name: M22755
exact_source: GO:0014891
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014891
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. [GOC:mtg_muscle]


systematic_name: M14748
exact_source: GO:0014896
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014896
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. [GOC:mtg_muscle]


systematic_name: M42674
exact_source: GO:0014901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage. [GOC:mtg_muscle]


systematic_name: M14770
exact_source: GO:0014902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:mtg_muscle]


systematic_name: M15444
exact_source: GO:0014904
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014904
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:mtg_muscle]


systematic_name: M29104
exact_source: GO:0014905
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014905
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:mtg_muscle]


systematic_name: M29105
exact_source: GO:0014908
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014908
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. [GOC:mtg_muscle]


systematic_name: M22757
exact_source: GO:0014909
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014909
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. [CL:0000192, GOC:mtg_muscle]


systematic_name: M14175
exact_source: GO:0014911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. [CL:0000192, GOC:mtg_muscle]


systematic_name: M12483
exact_source: GO:0014912
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014912
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. [CL:0000192, GOC:mtg_muscle]


systematic_name: M22758
exact_source: GO:0014916
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0014916
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure. [GOC:mtg_cardio]


systematic_name: M29106
exact_source: GO:0015012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues. [GOC:mah, ISBN:0198506732, ISBN:0198547684, RESID:AA0210]


systematic_name: M22759
exact_source: GO:0015014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan. [GOC:ai]


systematic_name: M22760
exact_source: GO:0015015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization. [ISBN:0815316194]


systematic_name: M48385
exact_source: GO:0015031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M11414
exact_source: GO:0015074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. [GOC:mah]


systematic_name: M13119
exact_source: GO:0015669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M34099
exact_source: GO:0015670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M13619
exact_source: GO:0015671
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015671
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M11541
exact_source: GO:0015693
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015693
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M14902
exact_source: GO:0015695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. [GOC:ai]


systematic_name: M12893
exact_source: GO:0015697
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015697
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups. [GOC:ai, ISBN:0198506732]


systematic_name: M11296
exact_source: GO:0015698
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015698
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. [GOC:krc]


systematic_name: M13560
exact_source: GO:0015701
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015701
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22762
exact_source: GO:0015705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M13556
exact_source: GO:0015711
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015711
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. [GOC:ai, GOC:krc]


systematic_name: M22763
exact_source: GO:0015712
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015712
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M14456
exact_source: GO:0015718
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015718
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M13647
exact_source: GO:0015721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511]


systematic_name: M22765
exact_source: GO:0015732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22767
exact_source: GO:0015740
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015740
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms. [GOC:krc, GOC:mah]


systematic_name: M42676
exact_source: GO:0015742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22770
exact_source: GO:0015747
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015747
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M12017
exact_source: GO:0015748
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015748
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds. [GOC:mcc]


systematic_name: M48386
exact_source: GO:0015749
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015749
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. [GO_REF:0000069, GOC:TermGenie, GOC:vw]


systematic_name: M42677
exact_source: GO:0015755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. [GOC:ai]


systematic_name: M45090
exact_source: GO:0015757
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015757
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. [GOC:ai]


systematic_name: M22771
exact_source: GO:0015780
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015780
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. [ISBN:0198506732]


systematic_name: M22772
exact_source: GO:0015793
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015793
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glycerol across a membrane. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. [GOC:ai]


systematic_name: M14313
exact_source: GO:0015800
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015800
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22773
exact_source: GO:0015801
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015801
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M13466
exact_source: GO:0015802
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015802
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22774
exact_source: GO:0015803
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015803
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings. [GOC:ai, GOC:bf]


systematic_name: M15992
exact_source: GO:0015804
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015804
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M45822
exact_source: GO:0015807
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015807
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai, GOC:jsg, GOC:mah]


systematic_name: M22775
exact_source: GO:0015808
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015808
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai, GOC:jsg, GOC:mah]


systematic_name: M22777
exact_source: GO:0015810
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015810
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42678
exact_source: GO:0015811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22778
exact_source: GO:0015812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators, ISBN:0198506732]


systematic_name: M46746
exact_source: GO:0015813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore. [PMID:21307582]


systematic_name: M22780
exact_source: GO:0015816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M45823
exact_source: GO:0015818
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015818
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M34102
exact_source: GO:0015820
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015820
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22781
exact_source: GO:0015822
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015822
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22782
exact_source: GO:0015824
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015824
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M34103
exact_source: GO:0015827
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015827
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M42679
exact_source: GO:0015833
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015833
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22784
exact_source: GO:0015837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai, ISBN:0198506732]


systematic_name: M11866
exact_source: GO:0015838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22785
exact_source: GO:0015840
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015840
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2. [GOC:ai, ISBN:0198506732]


systematic_name: M16521
exact_source: GO:0015844
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015844
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M22786
exact_source: GO:0015846
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015846
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc, ISBN:0198506732]


systematic_name: M46747
exact_source: GO:0015848
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015848
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc, ISBN:0198506732]


systematic_name: M11909
exact_source: GO:0015849
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015849
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [ISBN:0198506732]


systematic_name: M11947
exact_source: GO:0015850
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015850
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. [GOC:ai]


systematic_name: M22787
exact_source: GO:0015851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [ISBN:0198506732]


systematic_name: M45091
exact_source: GO:0015853
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015853
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:go_curators, ISBN:0198506732]


systematic_name: M15329
exact_source: GO:0015858
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015858
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M46748
exact_source: GO:0015860
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015860
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar. [GOC:ai, GOC:vw]


systematic_name: M48387
exact_source: GO:0015862
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015862
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of uridine, uracil riboside, across a lipid bilayer, by means of some agent such as a transporter or pore. [GOC:go_curators]


systematic_name: M13929
exact_source: GO:0015865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell. [GOC:ai]


systematic_name: M40385
exact_source: GO:0015866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22789
exact_source: GO:0015867
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015867
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22790
exact_source: GO:0015871
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015871
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. [GOC:ai]


systematic_name: M16439
exact_source: GO:0015872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. [GOC:ai]


systematic_name: M22791
exact_source: GO:0015874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. [GOC:ai, ISBN:0198506732]


systematic_name: M40386
exact_source: GO:0015879
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015879
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. [GOC:ai]


systematic_name: M22792
exact_source: GO:0015884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. [GOC:ai]


systematic_name: M22793
exact_source: GO:0015886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M42680
exact_source: GO:0015888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver. [GOC:ai]


systematic_name: M22794
exact_source: GO:0015889
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015889
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M15938
exact_source: GO:0015908
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015908
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [GOC:ai]


systematic_name: M15724
exact_source: GO:0015909
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015909
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a long-chain fatty acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [GOC:ai]


systematic_name: M22795
exact_source: GO:0015911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a long-chain fatty acid from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [GOC:ai]


systematic_name: M14795
exact_source: GO:0015914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester. [GOC:ai]


systematic_name: M40387
exact_source: GO:0015917
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015917
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group. [GOC:ai]


systematic_name: M15161
exact_source: GO:0015918
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015918
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:ai]


systematic_name: M13429
exact_source: GO:0015931
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015931
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M10813
exact_source: GO:0015936
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015936
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. [ISBN:0198547684]


systematic_name: M15325
exact_source: GO:0015937
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015937
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. [ISBN:0198547684]


systematic_name: M48388
exact_source: GO:0015939
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015939
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. [GOC:ai, ISBN:0721662544]


systematic_name: M29109
exact_source: GO:0015942
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015942
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid. [ISBN:0198506732]


systematic_name: M14441
exact_source: GO:0015949
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015949
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule. [GOC:mah, ISBN:0306444747, ISBN:0471394831]


systematic_name: M29110
exact_source: GO:0015959
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015959
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. [GOC:ai]


systematic_name: M34106
exact_source: GO:0015961
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015961
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached. [GOC:ai]


systematic_name: M16137
exact_source: GO:0015980
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015980
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. [GOC:mah]


systematic_name: M29111
exact_source: GO:0015986
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015986
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. [ISBN:0716731363]


systematic_name: M48389
exact_source: GO:0015988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0015988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport. [GOC:mah]


systematic_name: M46749
exact_source: GO:0016024
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016024
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. [PMID:24533860]


systematic_name: M42681
exact_source: GO:0016032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle. [GOC:bf, GOC:jl, GOC:mah]


systematic_name: M15533
exact_source: GO:0016042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators]


systematic_name: M45824
exact_source: GO:0016045
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016045
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a stimulus from a bacterium is received and converted into a molecular signal. [GOC:hb]


systematic_name: M12357
exact_source: GO:0016048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. [GOC:hb]


systematic_name: M16570
exact_source: GO:0016049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. [GOC:ai]


systematic_name: M10786
exact_source: GO:0016050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. [GOC:mah]


systematic_name: M3786
exact_source: GO:0016051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [ISBN:0198506732]


systematic_name: M14508
exact_source: GO:0016052
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016052
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [ISBN:0198506732]


systematic_name: M11689
exact_source: GO:0016053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]


systematic_name: M13128
exact_source: GO:0016054
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016054
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]


systematic_name: M48390
exact_source: GO:0016055
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016055
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a target cell and ending with a change in cell state. [PMID:11532397]


systematic_name: M29112
exact_source: GO:0016056
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016056
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by the excitation of rhodopsin by a photon, and ending with the regulation of a downstream cellular process. [GOC:bf, GOC:dph, GOC:hb, GOC:signaling, GOC:tb]


systematic_name: M5804
exact_source: GO:0016071
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016071
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. [ISBN:0198506732]


systematic_name: M3080
exact_source: GO:0016072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes. [ISBN:0198506732]


systematic_name: M29113
exact_source: GO:0016073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. [ISBN:0198506732]


systematic_name: M10884
exact_source: GO:0016074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. [GOC:krc]


systematic_name: M15564
exact_source: GO:0016075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes. [GOC:ai]


systematic_name: M45093
exact_source: GO:0016076
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016076
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein. [ISBN:0198506732]


systematic_name: M42682
exact_source: GO:0016078
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016078
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. [GOC:ai]


systematic_name: M22803
exact_source: GO:0016079
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016079
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft. [GOC:jid, GOC:lmg]


systematic_name: M22804
exact_source: GO:0016081
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016081
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process. [PMID:15217342]


systematic_name: M22805
exact_source: GO:0016082
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016082
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane. [GOC:mah, PMID:15217342, PMID:23060190]


systematic_name: M29114
exact_source: GO:0016093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans. [PMID:11108713]


systematic_name: M22806
exact_source: GO:0016098
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016098
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton. [ISBN:0198547684]


systematic_name: M48391
exact_source: GO:0016101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units. [ISBN:0198547684]


systematic_name: M22808
exact_source: GO:0016102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units. [GOC:mah, ISBN:0198547684]


systematic_name: M22809
exact_source: GO:0016114
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016114
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. [GOC:ai]


systematic_name: M29115
exact_source: GO:0016115
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016115
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. [GOC:ai]


systematic_name: M15826
exact_source: GO:0016125
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016125
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [ISBN:0198547684]


systematic_name: M15206
exact_source: GO:0016126
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016126
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:go_curators]


systematic_name: M16685
exact_source: GO:0016137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. [ISBN:0198547684]


systematic_name: M22810
exact_source: GO:0016139
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016139
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound. [GOC:go_curators]


systematic_name: M15788
exact_source: GO:0016180
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016180
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres. [PMID:15196465, PMID:31815536]


systematic_name: M45094
exact_source: GO:0016183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles. [GOC:curators, PMID:10099709, PMID:20448150]


systematic_name: M22812
exact_source: GO:0016188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle. [GOC:curators, PMID:10099709]


systematic_name: M42683
exact_source: GO:0016191
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016191
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane. [GOC:curators, PMID:10099709, PMID:24596248]


systematic_name: M11413
exact_source: GO:0016192
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016192
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. [GOC:ai, GOC:mah, ISBN:08789310662000]


systematic_name: M22814
exact_source: GO:0016197
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016197
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane. [ISBN:0198506732]


systematic_name: M22815
exact_source: GO:0016198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth. [PMID:10218152]


systematic_name: M22816
exact_source: GO:0016199
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016199
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline. [PMID:11376484]


systematic_name: M45095
exact_source: GO:0016202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of striated muscle development. [GOC:go_curators]


systematic_name: M10586
exact_source: GO:0016233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins. [GOC:mah, GOC:rn, PMID:11349150, PMID:11352055]


systematic_name: M34108
exact_source: GO:0016237
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016237
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of autophagy where cytosolic components are ingested by late endosomes, lysosomes or yeast-type lytic vacuoles by direct invagination of the compartment membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. [PMID:14679207, PMID:15798367, PMID:16973210, PMID:9566964]


systematic_name: M22818
exact_source: GO:0016239
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016239
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. [GOC:go_curators, PMID:9412464]


systematic_name: M42684
exact_source: GO:0016240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere. [GOC:autophagy, GOC:mah]


systematic_name: M14040
exact_source: GO:0016242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. [GOC:go_curators]


systematic_name: M10908
exact_source: GO:0016254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane. [ISBN:0879695595]


systematic_name: M22820
exact_source: GO:0016255
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016255
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain. [ISBN:0879695595]


systematic_name: M22821
exact_source: GO:0016264
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016264
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids. [GOC:jid, ISBN:0716731363]


systematic_name: M15987
exact_source: GO:0016266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure. [GOC:mah, GOC:pr, PMID:10580130]


systematic_name: M42685
exact_source: GO:0016310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. [ISBN:0198506732]


systematic_name: M14717
exact_source: GO:0016311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of removing one or more phosphoric (ester or anhydride) residues from a molecule. [ISBN:0198506732]


systematic_name: M22822
exact_source: GO:0016321
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016321
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. [GOC:ai]


systematic_name: M22823
exact_source: GO:0016322
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016322
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development. [GOC:hb]


systematic_name: M11646
exact_source: GO:0016331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of embryonic epithelia are generated and organized. [GOC:jl]


systematic_name: M7966
exact_source: GO:0016338
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016338
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. [GOC:hb]


systematic_name: M11914
exact_source: GO:0016339
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016339
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction. [GOC:hb]


systematic_name: M10094
exact_source: GO:0016358
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016358
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. [GOC:aruk, GOC:bc, GOC:jl, ISBN:0198506732, PMID:22683681]


systematic_name: M34109
exact_source: GO:0016445
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016445
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The somatic process that results in the generation of sequence diversity of immunoglobulins. [GOC:add, GOC:ma, ISBN:0781735149]


systematic_name: M22824
exact_source: GO:0016479
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016479
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I. [GOC:go_curators]


systematic_name: M22825
exact_source: GO:0016485
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016485
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. [GOC:curators, GOC:jl, GOC:jsg]


systematic_name: M16507
exact_source: GO:0016540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein. [GOC:ai, PMID:9335337]


systematic_name: M22826
exact_source: GO:0016553
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016553
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s). [PMID:11092837]


systematic_name: M11831
exact_source: GO:0016556
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016556
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically. [GOC:curators]


systematic_name: M16241
exact_source: GO:0016558
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016558
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix. [ISBN:0716731363, PMID:11687502, PMID:11988772]


systematic_name: M22828
exact_source: GO:0016559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments. [GOC:mah, PMID:11687502, PMID:14754507]


systematic_name: M45825
exact_source: GO:0016562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol. [PMID:11687502]


systematic_name: M16065
exact_source: GO:0016601
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016601
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Rac subfamily relays a signal. [GOC:bf]


systematic_name: M13502
exact_source: GO:0016925
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016925
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein. [GOC:jl, PMID:11265250]


systematic_name: M22832
exact_source: GO:0016926
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0016926
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein. [GOC:jl, PMID:11265250]


systematic_name: M11937
exact_source: GO:0017004
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017004
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions. [GOC:jl, GOC:mah]


systematic_name: M22837
exact_source: GO:0017014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent addition of a nitric oxide group to an amino acid within a protein. [GOC:ai, PMID:20972426]


systematic_name: M11299
exact_source: GO:0017038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event. [GOC:ai]


systematic_name: M42687
exact_source: GO:0017062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents. [GOC:jl, http://www.brainyencyclopedia.com/]


systematic_name: M12887
exact_source: GO:0017085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects. [GOC:curators]


systematic_name: M22838
exact_source: GO:0017121
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017121
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE). [GOC:cjm, PMID:20043909, PMID:20302864]


systematic_name: M12183
exact_source: GO:0017145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. [GOC:jid, ISBN:0582227089]


systematic_name: M11812
exact_source: GO:0017148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:isa_complete]


systematic_name: M13877
exact_source: GO:0017156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels. [GOC:go_curators]


systematic_name: M13808
exact_source: GO:0017158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis. [GOC:go_curators]


systematic_name: M22839
exact_source: GO:0017183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria. [GOC:pde, PMID:20559380]


systematic_name: M22841
exact_source: GO:0017196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0017196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine. [RESID:AA0049]


systematic_name: M16191
exact_source: GO:0018022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. [GOC:ai]


systematic_name: M22843
exact_source: GO:0018057
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018057
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens. [ISBN:0198547684, RESID:AA0121]


systematic_name: M22845
exact_source: GO:0018095
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018095
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid. [RESID:AA0202]


systematic_name: M22846
exact_source: GO:0018103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom. [GOC:pr, PMID:7947762, RESID:AA0217]


systematic_name: M22850
exact_source: GO:0018230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine. [RESID:AA0106]


systematic_name: M22851
exact_source: GO:0018242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine. [RESID:AA0154]


systematic_name: M22852
exact_source: GO:0018243
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018243
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine. [RESID:AA0155]


systematic_name: M45827
exact_source: GO:0018279
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018279
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification. [GOC:jsg, RESID:AA0151, RESID:AA0420, RESID:AA0421]


systematic_name: M22855
exact_source: GO:0018401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase. [RESID:AA0030]


systematic_name: M10178
exact_source: GO:0018904
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018904
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds. [GOC:pr, ISBN:0198506732]


systematic_name: M10130
exact_source: GO:0018958
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0018958
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. [ISBN:0198506732]


systematic_name: M46751
exact_source: GO:0019048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a virus effects a change in the structure or processes of its host organism. [GOC:bf, GOC:jl, ISBN:0781718325, UniProtKB-KW:KW-0945]


systematic_name: M13783
exact_source: GO:0019058
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019058
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome. [ISBN:1555811272]


systematic_name: M45097
exact_source: GO:0019065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell. [GOC:bf, GOC:jl, ISBN:0781702534]


systematic_name: M14097
exact_source: GO:0019068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed. [ISBN:0121585336]


systematic_name: M34112
exact_source: GO:0019076
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019076
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane. [GOC:jl]


systematic_name: M13578
exact_source: GO:0019079
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019079
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved directly in viral genome replication, including viral nucleotide metabolism. [ISBN:0781702534]


systematic_name: M22858
exact_source: GO:0019080
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019080
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation. [GOC:bf, GOC:jl, ISBN:0121585336]


systematic_name: M22859
exact_source: GO:0019081
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019081
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process by which viral mRNA is translated into viral protein, using the host cellular machinery. [GOC:bf, GOC:jl, ISBN:0781702534]


systematic_name: M42688
exact_source: GO:0019082
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019082
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein. [GOC:bf, GOC:jl, ISBN:0781702534]


systematic_name: M42689
exact_source: GO:0019083
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019083
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. [GOC:jl, ISBN:0781702534]


systematic_name: M12996
exact_source: GO:0019184
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019184
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione. [ISBN:0198506732]


systematic_name: M12303
exact_source: GO:0019216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. [GOC:go_curators]


systematic_name: M11936
exact_source: GO:0019217
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019217
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids. [GOC:go_curators]


systematic_name: M15200
exact_source: GO:0019218
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019218
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. [GOC:go_curators]


systematic_name: M898
exact_source: GO:0019221
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019221
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:19295629]


systematic_name: M8461
exact_source: GO:0019226
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019226
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. [GOC:curators, ISBN:0815316194]


systematic_name: M14342
exact_source: GO:0019229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels. [GOC:jl]


systematic_name: M22862
exact_source: GO:0019230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. [ISBN:072168677X]


systematic_name: M12273
exact_source: GO:0019233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. [GOC:curators]


systematic_name: M22863
exact_source: GO:0019236
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019236
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. [GOC:jl]


systematic_name: M22864
exact_source: GO:0019240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. [ISBN:0198506732]


systematic_name: M22865
exact_source: GO:0019262
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019262
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. [ISBN:0198506732]


systematic_name: M22866
exact_source: GO:0019317
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019317
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose). [GOC:jl]


systematic_name: M16303
exact_source: GO:0019321
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019321
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule. [ISBN:0198506732]


systematic_name: M22868
exact_source: GO:0019336
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019336
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. [ISBN:0198506732]


systematic_name: M42691
exact_source: GO:0019363
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019363
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base. [GOC:jl, GOC:pde, GOC:vw]


systematic_name: M15944
exact_source: GO:0019369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. [ISBN:0198506732]


systematic_name: M11524
exact_source: GO:0019370
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019370
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. [GOC:go_curators]


systematic_name: M14352
exact_source: GO:0019371
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019371
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2. [PMID:19854273]


systematic_name: M12487
exact_source: GO:0019372
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019372
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. [GOC:mah, PMID:17163881]


systematic_name: M16166
exact_source: GO:0019373
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019373
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids. [GOC:mah, PMID:17979511]


systematic_name: M29122
exact_source: GO:0019374
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019374
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine. [ISBN:0198506732]


systematic_name: M12373
exact_source: GO:0019377
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019377
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). [GOC:go_curators]


systematic_name: M22872
exact_source: GO:0019388
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019388
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. [ISBN:0198506732]


systematic_name: M12277
exact_source: GO:0019400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. [ISBN:0198506732]


systematic_name: M22873
exact_source: GO:0019401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. [ISBN:0198506732]


systematic_name: M22874
exact_source: GO:0019405
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019405
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group. [ISBN:0198506732]


systematic_name: M34114
exact_source: GO:0019432
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019432
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. [ISBN:0198506732]


systematic_name: M14112
exact_source: GO:0019433
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019433
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol. [ISBN:0198506732]


systematic_name: M22876
exact_source: GO:0019441
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019441
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine. [GOC:go_curators]


systematic_name: M48394
exact_source: GO:0019471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls. [GOC:ai]


systematic_name: M22877
exact_source: GO:0019509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. [GOC:jl, MetaCyc:PWY-4361]


systematic_name: M45829
exact_source: GO:0019530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. [GOC:jl, ISBN:0198600461]


systematic_name: M14246
exact_source: GO:0019532
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019532
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals. [ISBN:0198506732]


systematic_name: M46752
exact_source: GO:0019541
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019541
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40391
exact_source: GO:0019614
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019614
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. [GOC:go_curators]


systematic_name: M22880
exact_source: GO:0019626
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019626
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a short-chain fatty acid. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons. [ISBN:0198506732]


systematic_name: M11372
exact_source: GO:0019637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. [ISBN:0198506732]


systematic_name: M46753
exact_source: GO:0019640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate. [GOC:go_curators]


systematic_name: M29124
exact_source: GO:0019673
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019673
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate. [GOC:ai]


systematic_name: M11823
exact_source: GO:0019674
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019674
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. [GOC:jl, ISBN:0618254153]


systematic_name: M48395
exact_source: GO:0019677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:jl, ISBN:0618254153]


systematic_name: M45099
exact_source: GO:0019682
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019682
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis. [GOC:ai, ISBN:0198506732]


systematic_name: M45831
exact_source: GO:0019693
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019693
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. [GOC:ai]


systematic_name: M29127
exact_source: GO:0019695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. [GOC:jl, ISBN:0192801023]


systematic_name: M488
exact_source: GO:0019722
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019722
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. [GOC:signaling]


systematic_name: M12033
exact_source: GO:0019724
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019724
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. [GO_REF:0000022, GOC:add, ISBN:0781735149]


systematic_name: M5826
exact_source: GO:0019725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state at the level of the cell. [GOC:isa_complete, GOC:jl, ISBN:0395825172]


systematic_name: M10380
exact_source: GO:0019730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus. [GOC:go_curators, GOC:mtg_sensu]


systematic_name: M22882
exact_source: GO:0019731
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019731
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster. [GOC:go_curators, GOC:mtg_sensu]


systematic_name: M22883
exact_source: GO:0019732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster. [GOC:go_curators, GOC:mtg_sensu]


systematic_name: M48396
exact_source: GO:0019740
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019740
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism. [GOC:mah, GOC:mlg]


systematic_name: M3773
exact_source: GO:0019748
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019748
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. [GOC:go_curators]


systematic_name: M11003
exact_source: GO:0019751
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019751
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. [PMID:30240188]


systematic_name: M12933
exact_source: GO:0019755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M12523
exact_source: GO:0019852
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019852
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. [GOC:jl, ISBN:0198506732]


systematic_name: M22886
exact_source: GO:0019856
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019856
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. [GOC:go_curators]


systematic_name: M12794
exact_source: GO:0019882
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019882
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678]


systematic_name: M16324
exact_source: GO:0019883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex. [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678]


systematic_name: M42695
exact_source: GO:0019884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex. [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678]


systematic_name: M42696
exact_source: GO:0019886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein. [GOC:add, ISBN:0781735149, PMID:15771591]


systematic_name: M15541
exact_source: GO:0019915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development. [GOC:dph, GOC:mah, GOC:tb, PMID:11102830]


systematic_name: M48397
exact_source: GO:0019919
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019919
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine. [RESID:AA0068, RESID:AA0069]


systematic_name: M1237
exact_source: GO:0019933
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019933
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette that starts with production of cyclic AMP (cAMP), and ends with activation of downstream effectors that further transmit the signal within the cell. [GOC:signaling]


systematic_name: M22889
exact_source: GO:0019934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette that starts with production of cyclic GMP (cGMP), and ends with activation of downstream effectors that further transmit the signal within the cell. [GOC:signaling]


systematic_name: M45100
exact_source: GO:0019953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). [Wikipedia:Sexual_reproduction]


systematic_name: M13848
exact_source: GO:0019985
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0019985
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide. [GOC:elh, GOC:vw, PMID:10535901]


systematic_name: M10121
exact_source: GO:0020027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0020027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving hemoglobin, including its uptake and utilization. [GOC:go_curators, GOC:jl]


systematic_name: M10048
exact_source: GO:0021510
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021510
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M13455
exact_source: GO:0021511
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021511
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M13534
exact_source: GO:0021514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M11744
exact_source: GO:0021515
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021515
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M15849
exact_source: GO:0021516
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021516
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11179871]


systematic_name: M12078
exact_source: GO:0021517
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021517
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M12366
exact_source: GO:0021520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M11842
exact_source: GO:0021522
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021522
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M22890
exact_source: GO:0021523
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021523
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M14634
exact_source: GO:0021527
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021527
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M34117
exact_source: GO:0021529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M16543
exact_source: GO:0021532
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021532
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M13307
exact_source: GO:0021533
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021533
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22891
exact_source: GO:0021534
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021534
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M14895
exact_source: GO:0021535
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021535
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell that will reside in the hindbrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M14556
exact_source: GO:0021536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M15958
exact_source: GO:0021537
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021537
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M22892
exact_source: GO:0021540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M10141
exact_source: GO:0021542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M13343
exact_source: GO:0021543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M16379
exact_source: GO:0021544
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021544
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M11618
exact_source: GO:0021545
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021545
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22893
exact_source: GO:0021546
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021546
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M12684
exact_source: GO:0021548
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021548
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M42697
exact_source: GO:0021553
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021553
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M13111
exact_source: GO:0021554
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021554
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22894
exact_source: GO:0021559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22895
exact_source: GO:0021562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M45101
exact_source: GO:0021563
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021563
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M14739
exact_source: GO:0021575
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021575
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M42698
exact_source: GO:0021578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M11577
exact_source: GO:0021591
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021591
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M11378
exact_source: GO:0021602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22897
exact_source: GO:0021603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22898
exact_source: GO:0021604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22899
exact_source: GO:0021610
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021610
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M42699
exact_source: GO:0021612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22901
exact_source: GO:0021626
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021626
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089]


systematic_name: M42700
exact_source: GO:0021631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22904
exact_source: GO:0021648
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021648
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M29128
exact_source: GO:0021650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M14885
exact_source: GO:0021670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M13527
exact_source: GO:0021675
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021675
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M16365
exact_source: GO:0021680
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021680
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M12526
exact_source: GO:0021681
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021681
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22905
exact_source: GO:0021683
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021683
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M22906
exact_source: GO:0021684
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021684
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M15961
exact_source: GO:0021692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M11027
exact_source: GO:0021694
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021694
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M12585
exact_source: GO:0021695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M11224
exact_source: GO:0021696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M15386
exact_source: GO:0021697
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021697
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343]


systematic_name: M3318
exact_source: GO:0021700
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021700
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15431
exact_source: GO:0021756
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021756
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420]


systematic_name: M16247
exact_source: GO:0021761
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021761
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420]


systematic_name: M13060
exact_source: GO:0021762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343, ISBN:0878937420]


systematic_name: M42702
exact_source: GO:0021764
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021764
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420]


systematic_name: M12672
exact_source: GO:0021766
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021766
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the hippocampus over time from its initial formation until its mature state. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420, UBERON:0002421]


systematic_name: M45102
exact_source: GO:0021780
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021780
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M14935
exact_source: GO:0021781
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021781
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M11130
exact_source: GO:0021782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22908
exact_source: GO:0021785
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021785
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:14699587]


systematic_name: M14842
exact_source: GO:0021794
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021794
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the thalamus changes over time, from its initial formation to its mature state. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15506
exact_source: GO:0021795
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021795
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of cells from one site to another in the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22909
exact_source: GO:0021796
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021796
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22910
exact_source: GO:0021798
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021798
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15776
exact_source: GO:0021799
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021799
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M22911
exact_source: GO:0021800
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021800
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M22912
exact_source: GO:0021814
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021814
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M45833
exact_source: GO:0021815
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021815
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M11199
exact_source: GO:0021819
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021819
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M12613
exact_source: GO:0021826
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021826
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M42703
exact_source: GO:0021830
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021830
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of interneurons from the subpallium to the cortex during forebrain development. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M11623
exact_source: GO:0021846
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021846
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M48398
exact_source: GO:0021853
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021853
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M12165
exact_source: GO:0021854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M42704
exact_source: GO:0021855
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021855
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a cell into the hypothalamus region of the forebrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22915
exact_source: GO:0021859
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021859
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M42705
exact_source: GO:0021860
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021860
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of a pyramidal neuron from its initial formation to its mature state. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22916
exact_source: GO:0021861
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021861
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]


systematic_name: M22917
exact_source: GO:0021869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The mitotic division of a basal progenitor giving rise to two neurons. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]


systematic_name: M11910
exact_source: GO:0021871
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021871
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:16226447]


systematic_name: M11912
exact_source: GO:0021872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M42706
exact_source: GO:0021873
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021873
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15633
exact_source: GO:0021877
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021877
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]


systematic_name: M42707
exact_source: GO:0021879
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021879
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447]


systematic_name: M10074
exact_source: GO:0021884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M11998
exact_source: GO:0021885
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021885
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell from one site to another at least one of which is located in the forebrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M42708
exact_source: GO:0021886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M10208
exact_source: GO:0021889
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021889
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M16106
exact_source: GO:0021891
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021891
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M13737
exact_source: GO:0021892
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021892
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M22920
exact_source: GO:0021894
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021894
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695]


systematic_name: M12325
exact_source: GO:0021895
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021895
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M12735
exact_source: GO:0021903
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021903
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the neural tube is divided into specific regions along the rostrocaudal axis. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M13873
exact_source: GO:0021904
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021904
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the neural tube is regionalized in the dorsoventral axis. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869]


systematic_name: M11393
exact_source: GO:0021915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22923
exact_source: GO:0021932
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021932
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]


systematic_name: M42709
exact_source: GO:0021934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22924
exact_source: GO:0021936
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021936
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that modulates the frequency, rate or extent of granule cell precursor proliferation. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]


systematic_name: M22926
exact_source: GO:0021940
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021940
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that activates or increases the rate or extent of granule cell precursor proliferation. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725]


systematic_name: M13810
exact_source: GO:0021952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M13421
exact_source: GO:0021953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15685
exact_source: GO:0021954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M16736
exact_source: GO:0021955
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021955
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22928
exact_source: GO:0021957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:9878731]


systematic_name: M22929
exact_source: GO:0021960
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021960
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878937420]


systematic_name: M15512
exact_source: GO:0021978
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021978
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mgi_curators]


systematic_name: M22930
exact_source: GO:0021979
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021979
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The differentiation of cells that will contribute to the structure and function of the hypothalamus. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, GOC:mgi_curators]


systematic_name: M11324
exact_source: GO:0021983
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021983
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M15797
exact_source: GO:0021984
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021984
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M12873
exact_source: GO:0021987
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021987
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M14319
exact_source: GO:0021988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0021988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M11351
exact_source: GO:0022008
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022008
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of cells within the nervous system. [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M46754
exact_source: GO:0022027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M22933
exact_source: GO:0022028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M12797
exact_source: GO:0022030
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022030
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of glial cells through the telencephalon. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M10347
exact_source: GO:0022037
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022037
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M16907
exact_source: GO:0022038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid]


systematic_name: M46755
exact_source: GO:0022401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. [GOC:isa_complete]


systematic_name: M17773
exact_source: GO:0022402
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022402
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. [GOC:isa_complete, GOC:mtg_cell_cycle]


systematic_name: M45834
exact_source: GO:0022404
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022404
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. [GOC:isa_complete]


systematic_name: M11875
exact_source: GO:0022406
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022406
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. [GOC:isa_complete, PMID:27875684]


systematic_name: M6401
exact_source: GO:0022407
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022407
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. [GOC:isa_complete]


systematic_name: M11239
exact_source: GO:0022408
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022408
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. [GOC:isa_complete]


systematic_name: M14725
exact_source: GO:0022409
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022409
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of cell adhesion to another cell. [GOC:isa_complete]


systematic_name: M13832
exact_source: GO:0022412
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022412
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. [GOC:isa_complete]


systematic_name: M48399
exact_source: GO:0022414
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022414
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. [GOC:dph, GOC:isa_complete]


systematic_name: M22935
exact_source: GO:0022417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein. [GOC:isa_complete]


systematic_name: M13988
exact_source: GO:0022600
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022600
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [GOC:isa_complete, GOC:jid, GOC:mtg_cardio]


systematic_name: M12867
exact_source: GO:0022602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. [GOC:isa_complete]


systematic_name: M7769
exact_source: GO:0022603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. [GOC:mah]


systematic_name: M10484
exact_source: GO:0022604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. [GOC:isa_complete]


systematic_name: M22936
exact_source: GO:0022605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. [GOC:isa_complete, GOC:mtg_sensu]


systematic_name: M10421
exact_source: GO:0022612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a gland are generated and organized. [GOC:isa_complete]


systematic_name: M16027
exact_source: GO:0022613
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022613
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. [GOC:isa_complete, GOC:mah]


systematic_name: M22937
exact_source: GO:0022614
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022614
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere. [GOC:isa_complete]


systematic_name: M45835
exact_source: GO:0022615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere. [GOC:isa_complete]


systematic_name: M13628
exact_source: GO:0022616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand. [GOC:isa_complete, GOC:mah]


systematic_name: M13293
exact_source: GO:0022900
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0022900
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors. [GOC:mtg_electron_transport]


systematic_name: M16934
exact_source: GO:0023019
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023019
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. [GOC:mtg_signal]


systematic_name: M22939
exact_source: GO:0023035
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023035
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mtg_signal, GOC:signaling, PMID:11348017]


systematic_name: M22940
exact_source: GO:0023041
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023041
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular. [GOC:mtg_signal]


systematic_name: M46756
exact_source: GO:0023056
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023056
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. [GOC:mtg_signal]


systematic_name: M22942
exact_source: GO:0023057
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023057
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. [GOC:mtg_signal]


systematic_name: M13839
exact_source: GO:0023061
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0023061
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. [GOC:mtg_signal]


systematic_name: M13241
exact_source: GO:0030002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom. [GOC:ceb, GOC:mah]


systematic_name: M13288
exact_source: GO:0030007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell. [GOC:mah]


systematic_name: M12181
exact_source: GO:0030010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specification and formation of anisotropic intracellular organization or cell growth patterns. [GOC:mah]


systematic_name: M13745
exact_source: GO:0030011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The maintenance of established anisotropic intracellular organization or cell growth patterns. [GOC:mah]


systematic_name: M9082
exact_source: GO:0030029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. [GOC:mah]


systematic_name: M15229
exact_source: GO:0030030
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030030
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/]


systematic_name: M3727
exact_source: GO:0030031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/]


systematic_name: M16776
exact_source: GO:0030032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. [GOC:mah, ISBN:0815316194]


systematic_name: M22943
exact_source: GO:0030033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. [GOC:mah, ISBN:0815316194]


systematic_name: M22945
exact_source: GO:0030046
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030046
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity. [GOC:mah, ISBN:0815316194]


systematic_name: M17820
exact_source: GO:0030048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. [GOC:BHF, GOC:mah]


systematic_name: M42711
exact_source: GO:0030070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges. [ISBN:0198506732]


systematic_name: M10906
exact_source: GO:0030073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. [GOC:mah, ISBN:0198506732]


systematic_name: M22950
exact_source: GO:0030091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues. [GOC:mlg]


systematic_name: M5376
exact_source: GO:0030097
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030097
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. [GOC:dgh, ISBN:0198506732]


systematic_name: M18190
exact_source: GO:0030098
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030098
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. [CL:0000542, GOC:go_curators]


systematic_name: M10009
exact_source: GO:0030099
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030099
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. [GOC:add, ISBN:0781735149]


systematic_name: M14057
exact_source: GO:0030101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M11440
exact_source: GO:0030111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M15003
exact_source: GO:0030148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:mah, ISBN:0198506732]


systematic_name: M15922
exact_source: GO:0030150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. [ISBN:0716731363]


systematic_name: M8154
exact_source: GO:0030155
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030155
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. [GOC:mah]


systematic_name: M22951
exact_source: GO:0030157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. [GOC:mah, ISBN:0198506732]


systematic_name: M16059
exact_source: GO:0030162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. [GOC:mah]


systematic_name: M16362
exact_source: GO:0030163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. [GOC:mah]


systematic_name: M3215
exact_source: GO:0030166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN:0198506732]


systematic_name: M45104
exact_source: GO:0030167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN:0198506732]


systematic_name: M10857
exact_source: GO:0030168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. [http://www.graylab.ac.uk/omd/]


systematic_name: M22952
exact_source: GO:0030174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase. [GOC:mah]


systematic_name: M15507
exact_source: GO:0030177
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030177
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of Wnt signal transduction. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M16074
exact_source: GO:0030178
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030178
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M5982
exact_source: GO:0030183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. [GO_REF:0000022, GOC:mah]


systematic_name: M42712
exact_source: GO:0030185
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030185
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M10505
exact_source: GO:0030199
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030199
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. [GOC:mah, ISBN:0815316194]


systematic_name: M45105
exact_source: GO:0030200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. [GOC:mah, ISBN:0198506732]


systematic_name: M12969
exact_source: GO:0030201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups. [GOC:mah, ISBN:0198506732]


systematic_name: M29129
exact_source: GO:0030202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:mah, ISBN:0198506732]


systematic_name: M46757
exact_source: GO:0030204
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030204
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate. [GOC:mah, ISBN:0198506732]


systematic_name: M29130
exact_source: GO:0030205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues. [GOC:mah, ISBN:0198506732]


systematic_name: M13500
exact_source: GO:0030206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. [GOC:mah, ISBN:0198506732]


systematic_name: M42713
exact_source: GO:0030208
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030208
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. [GOC:mah, ISBN:0198506732]


systematic_name: M42714
exact_source: GO:0030210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues. [GOC:mah, ISBN:0198506732]


systematic_name: M12268
exact_source: GO:0030212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. [GOC:mah, ISBN:0198506732]


systematic_name: M22956
exact_source: GO:0030213
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030213
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. [GOC:mah, ISBN:0198506732]


systematic_name: M11100
exact_source: GO:0030214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. [GOC:mah, ISBN:0198506732]


systematic_name: M29131
exact_source: GO:0030216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. [GOC:dph, GOC:mah, GOC:sdb_2009, GOC:tb]


systematic_name: M18127
exact_source: GO:0030217
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030217
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. [GO_REF:0000022, GOC:jid, GOC:mah]


systematic_name: M14514
exact_source: GO:0030219
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030219
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. [GOC:mah]


systematic_name: M22957
exact_source: GO:0030222
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030222
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. [GOC:add, GOC:mah]


systematic_name: M22958
exact_source: GO:0030223
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030223
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a myeloid precursor cell acquires the specialized features of a neutrophil. [GOC:mah]


systematic_name: M40397
exact_source: GO:0030224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. [GOC:mah]


systematic_name: M14853
exact_source: GO:0030225
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030225
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. [GOC:add, ISBN:0781735149]


systematic_name: M29132
exact_source: GO:0030240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle. [GOC:ef, GOC:mah, GOC:mtg_muscle]


systematic_name: M22959
exact_source: GO:0030242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions. [GOC:autophagy, PMID:10547367, PMID:20083110]


systematic_name: M10113
exact_source: GO:0030258
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030258
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid. [GOC:mah]


systematic_name: M11637
exact_source: GO:0030261
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030261
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. [GOC:mah, ISBN:0815316194]


systematic_name: M13425
exact_source: GO:0030277
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030277
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents. [GOC:mah]


systematic_name: M16923
exact_source: GO:0030278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:go_curators]


systematic_name: M15467
exact_source: GO:0030279
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030279
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:go_curators]


systematic_name: M12864
exact_source: GO:0030282
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030282
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. [GOC:mah, PMID:22936354]


systematic_name: M12857
exact_source: GO:0030307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, extent or direction of cell growth. [GOC:go_curators]


systematic_name: M10876
exact_source: GO:0030308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. [GOC:go_curators]


systematic_name: M29134
exact_source: GO:0030309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n. [GOC:mah, PMID:9405606]


systematic_name: M16135
exact_source: GO:0030316
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030316
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. [CL:0000092, GOC:add, ISBN:0781735149, PMID:12161749]


systematic_name: M15931
exact_source: GO:0030318
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030318
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. [GOC:mah]


systematic_name: M16676
exact_source: GO:0030322
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030322
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:jl, ISBN:0198506732]


systematic_name: M13778
exact_source: GO:0030325
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030325
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. [GOC:dgh]


systematic_name: M8378
exact_source: GO:0030330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage. [GOC:go_curators]


systematic_name: M22966
exact_source: GO:0030388
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030388
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis. [ISBN:0198506732]


systematic_name: M10723
exact_source: GO:0030397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. [GOC:mah]


systematic_name: M22967
exact_source: GO:0030422
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030422
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase. [GOC:mah, PMID:11524674, PMID:19239886, PMID:20687832]


systematic_name: M14903
exact_source: GO:0030431
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030431
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. [ISBN:0192800981]


systematic_name: M22968
exact_source: GO:0030432
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030432
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. [ISBN:0198506732]


systematic_name: M40399
exact_source: GO:0030449
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030449
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of complement activation. [GOC:go_curators]


systematic_name: M42716
exact_source: GO:0030450
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030450
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the classical pathway of complement activation. [GOC:go_curators]


systematic_name: M34120
exact_source: GO:0030451
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030451
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation. [GOC:go_curators]


systematic_name: M45838
exact_source: GO:0030473
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030473
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. [GOC:mah, GOC:sgd_curators]


systematic_name: M13570
exact_source: GO:0030488
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030488
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. [GOC:mah]


systematic_name: M10864
exact_source: GO:0030490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule. [GOC:curators]


systematic_name: M16897
exact_source: GO:0030497
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030497
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The elongation of a fatty acid chain by the sequential addition of two-carbon units. [ISBN:0716720094]


systematic_name: M22972
exact_source: GO:0030501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of bone mineralization. [GOC:go_curators]


systematic_name: M22973
exact_source: GO:0030502
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030502
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. [GOC:go_curators]


systematic_name: M14928
exact_source: GO:0030510
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030510
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway. [GOC:mah]


systematic_name: M40400
exact_source: GO:0030512
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030512
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway. [GOC:mah]


systematic_name: M12261
exact_source: GO:0030513
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030513
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity. [GOC:go_curators]


systematic_name: M13373
exact_source: GO:0030514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway. [GOC:go_curators]


systematic_name: M10588
exact_source: GO:0030517
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030517
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth. [GOC:mah]


systematic_name: M16829
exact_source: GO:0030520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by estrogen binding to its nuclear receptor inside the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]


systematic_name: M15861
exact_source: GO:0030521
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030521
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by androgen binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah]


systematic_name: M14730
exact_source: GO:0030522
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030522
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a receptor located within a cell. [GOC:bf, GOC:mah]


systematic_name: M10795
exact_source: GO:0030539
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030539
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. [GOC:ems, ISBN:0140512888]


systematic_name: M16109
exact_source: GO:0030540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. [GOC:mah]


systematic_name: M22974
exact_source: GO:0030574
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030574
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. [GOC:mah, ISBN:0815316194]


systematic_name: M22975
exact_source: GO:0030575
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030575
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M22976
exact_source: GO:0030578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia). [GOC:mah, PMID:10806078]


systematic_name: M34121
exact_source: GO:0030593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. [GOC:jl, ISBN:0198506732]


systematic_name: M42717
exact_source: GO:0030638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps. [GOC:mah, ISBN:0198506732]


systematic_name: M45839
exact_source: GO:0030643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell. [GOC:mah]


systematic_name: M29135
exact_source: GO:0030647
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030647
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin. [GOC:mah, ISBN:0198506732]


systematic_name: M11781
exact_source: GO:0030656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. [GOC:mah]


systematic_name: M8785
exact_source: GO:0030705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. [GOC:mah]


systematic_name: M22979
exact_source: GO:0030730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system. [GOC:mah, ISBN:0198506732]


systematic_name: M22980
exact_source: GO:0030808
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030808
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. [GOC:mah]


systematic_name: M22982
exact_source: GO:0030810
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030810
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. [GOC:mah]


systematic_name: M48402
exact_source: GO:0030811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. [GOC:mah]


systematic_name: M48403
exact_source: GO:0030812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. [GOC:mah]


systematic_name: M48404
exact_source: GO:0030813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides. [GOC:mah]


systematic_name: M11349
exact_source: GO:0030835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization. [GOC:mah]


systematic_name: M16880
exact_source: GO:0030836
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030836
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of actin depolymerization. [GOC:mah]


systematic_name: M14995
exact_source: GO:0030837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization. [GOC:mah]


systematic_name: M15198
exact_source: GO:0030838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of actin polymerization. [GOC:mah]


systematic_name: M15794
exact_source: GO:0030850
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030850
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. [PMID:11839751]


systematic_name: M14361
exact_source: GO:0030851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. [GOC:ecd, http://life.nthu.edu.tw/~g864204/dict-search1.htm]


systematic_name: M22983
exact_source: GO:0030853
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030853
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. [GOC:mah]


systematic_name: M22984
exact_source: GO:0030854
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030854
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. [GOC:mah]


systematic_name: M3
exact_source: GO:0030855
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030855
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. [GOC:ecd, PMID:11839751]


systematic_name: M12058
exact_source: GO:0030856
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030856
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of epithelial cell differentiation. [GOC:mah]


systematic_name: M14860
exact_source: GO:0030857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. [GOC:mah]


systematic_name: M10054
exact_source: GO:0030858
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030858
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. [GOC:mah]


systematic_name: M13212
exact_source: GO:0030859
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030859
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis. [GOC:mah]


systematic_name: M16535
exact_source: GO:0030865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M34123
exact_source: GO:0030866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. [GOC:dph, GOC:jl, GOC:mah, GOC:pf]


systematic_name: M16540
exact_source: GO:0030878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. [GOC:dgh]


systematic_name: M13739
exact_source: GO:0030879
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030879
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. [PMID:9576833]


systematic_name: M11811
exact_source: GO:0030900
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030900
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain]


systematic_name: M13125
exact_source: GO:0030901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain]


systematic_name: M10170
exact_source: GO:0030902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain]


systematic_name: M15882
exact_source: GO:0030903
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030903
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. [GOC:dgh]


systematic_name: M22986
exact_source: GO:0030913
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030913
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier. [PMID:14715942]


systematic_name: M22987
exact_source: GO:0030916
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030916
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. [GOC:dgh]


systematic_name: M22988
exact_source: GO:0030917
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030917
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. [GOC:dgh]


systematic_name: M13223
exact_source: GO:0030947
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030947
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. [GOC:dgh]


systematic_name: M22989
exact_source: GO:0030948
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030948
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. [GOC:dgh]


systematic_name: M15928
exact_source: GO:0030949
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030949
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. [GOC:dgh]


systematic_name: M22991
exact_source: GO:0030952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. [GOC:mah]


systematic_name: M22992
exact_source: GO:0030953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles. [GOC:mah]


systematic_name: M22993
exact_source: GO:0030968
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0030968
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation. [GOC:mah, PMID:12042763]


systematic_name: M13820
exact_source: GO:0031000
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031000
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. [GOC:ef, GOC:mah]


systematic_name: M11915
exact_source: GO:0031016
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031016
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones. [GOC:cvs]


systematic_name: M22994
exact_source: GO:0031017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. [GOC:cvs]


systematic_name: M12875
exact_source: GO:0031018
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031018
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. [GOC:cvs]


systematic_name: M2497
exact_source: GO:0031023
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031023
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M13335
exact_source: GO:0031032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M22995
exact_source: GO:0031033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules. [GOC:mah]


systematic_name: M42718
exact_source: GO:0031047
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031047
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation. [PMID:15020054]


systematic_name: M48405
exact_source: GO:0031048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription. [PMID:19239886, PMID:21420348]


systematic_name: M22996
exact_source: GO:0031053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule. [GOC:sl, PMID:15211354, PMID:25799998]


systematic_name: M14987
exact_source: GO:0031054
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031054
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule. [GOC:sl, PMID:15211354]


systematic_name: M16446
exact_source: GO:0031076
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031076
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. [GOC:mah, GOC:mtg_sensu]


systematic_name: M23000
exact_source: GO:0031077
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031077
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. [GOC:mah, GOC:mtg_sensu]


systematic_name: M23001
exact_source: GO:0031086
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031086
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability. [GOC:krc, PMID:15225542, PMID:15225544]


systematic_name: M15977
exact_source: GO:0031098
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031098
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays a signal. [GOC:mah]


systematic_name: M11315
exact_source: GO:0031099
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031099
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). [GOC:mah, GOC:pr]


systematic_name: M14446
exact_source: GO:0031102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage. [GOC:dgh, GOC:dph, GOC:tb]


systematic_name: M3855
exact_source: GO:0031109
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031109
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. [GOC:mah]


systematic_name: M15466
exact_source: GO:0031110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. [GOC:mah]


systematic_name: M23003
exact_source: GO:0031111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. [GOC:mah]


systematic_name: M12519
exact_source: GO:0031112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. [GOC:mah]


systematic_name: M23005
exact_source: GO:0031115
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031115
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. [GOC:mah]


systematic_name: M10313
exact_source: GO:0031122
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031122
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. [GOC:mah]


systematic_name: M11326
exact_source: GO:0031128
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031128
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535]


systematic_name: M10781
exact_source: GO:0031145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome. [GOC:mah, PMID:15380083, PMID:15840442]


systematic_name: M14611
exact_source: GO:0031146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. [PMID:15380083]


systematic_name: M48406
exact_source: GO:0031163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster. [GOC:jl, GOC:mah, GOC:pde, GOC:vw]


systematic_name: M16419
exact_source: GO:0031167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule. [GOC:mah]


systematic_name: M23010
exact_source: GO:0031179
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031179
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide. [GOC:mah]


systematic_name: M23011
exact_source: GO:0031204
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031204
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a protein translocates through the ER membrane posttranslationally. [PMID:12518317, PMID:8707814]


systematic_name: M45841
exact_source: GO:0031214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. [PMID:15132736]


systematic_name: M23012
exact_source: GO:0031268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. [GOC:pg]


systematic_name: M42722
exact_source: GO:0031274
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031274
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. [GOC:pg]


systematic_name: M12125
exact_source: GO:0031284
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031284
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity. [GOC:mah]


systematic_name: M10833
exact_source: GO:0031290
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031290
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues. [GOC:ejs]


systematic_name: M13818
exact_source: GO:0031293
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031293
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. [PMID:12808018]


systematic_name: M11050
exact_source: GO:0031294
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031294
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation. [ISBN:0781735149]


systematic_name: M45107
exact_source: GO:0031329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. [GOC:mah]


systematic_name: M10886
exact_source: GO:0031330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. [GOC:mah]


systematic_name: M45108
exact_source: GO:0031331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. [GOC:mah]


systematic_name: M10120
exact_source: GO:0031333
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031333
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. [GOC:mah]


systematic_name: M14368
exact_source: GO:0031334
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031334
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of protein complex assembly. [GOC:mah]


systematic_name: M16351
exact_source: GO:0031341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. [GOC:mah]


systematic_name: M16248
exact_source: GO:0031342
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031342
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. [GOC:mah]


systematic_name: M12444
exact_source: GO:0031344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. [GOC:mah]


systematic_name: M14191
exact_source: GO:0031345
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031345
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. [GOC:mah]


systematic_name: M16921
exact_source: GO:0031346
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031346
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. [GOC:mah]


systematic_name: M13454
exact_source: GO:0031348
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031348
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. [GOC:mah]


systematic_name: M9888
exact_source: GO:0031349
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031349
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a defense response. [GOC:mah]


systematic_name: M40401
exact_source: GO:0031393
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031393
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. [GOC:mah]


systematic_name: M29140
exact_source: GO:0031394
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031394
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin. [GOC:mah]


systematic_name: M45109
exact_source: GO:0031396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein. [GOC:mah]


systematic_name: M46761
exact_source: GO:0031397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein. [GOC:mah]


systematic_name: M46762
exact_source: GO:0031398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein. [GOC:mah]


systematic_name: M17904
exact_source: GO:0031399
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031399
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb]


systematic_name: M16497
exact_source: GO:0031400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb]


systematic_name: M9604
exact_source: GO:0031401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. [GOC:mah, GOC:tb]


systematic_name: M15449
exact_source: GO:0031424
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031424
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. [GOC:dph, GOC:ebc, GOC:sdb_2009, GOC:tb]


systematic_name: M12745
exact_source: GO:0031440
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031440
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule. [GOC:mah]


systematic_name: M48407
exact_source: GO:0031445
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031445
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, extent or location of heterochromatin formation. [GOC:mah]


systematic_name: M48408
exact_source: GO:0031452
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031452
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. [PMID:16855380]


systematic_name: M10274
exact_source: GO:0031468
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031468
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The reformation of the nuclear membranes following their breakdown in the context of a normal process. [GOC:mah]


systematic_name: M23022
exact_source: GO:0031503
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031503
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. [GOC:mah]


systematic_name: M48409
exact_source: GO:0031507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation. [PMID:25192661, PMID:33827924]


systematic_name: M46763
exact_source: GO:0031508
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031508
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA. [GOC:mah, PMID:14612388, PMID:20206496, PMID:22729156]


systematic_name: M42724
exact_source: GO:0031509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The compaction of chromatin into heterochromatin at the subtelomeric region. [GOC:mah, PMID:10219245, PMID:26205977]


systematic_name: M16214
exact_source: GO:0031529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell. [GOC:mah, PMID:10036235]


systematic_name: M48410
exact_source: GO:0031536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity). [GOC:mah]


systematic_name: M23025
exact_source: GO:0031547
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031547
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands. [GOC:mah]


systematic_name: M46764
exact_source: GO:0031554
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031554
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. [GOC:mlg, GOC:txnOH]


systematic_name: M16357
exact_source: GO:0031570
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031570
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes. [GOC:mtg_cell_cycle]


systematic_name: M11926
exact_source: GO:0031573
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031573
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression. [GOC:vw]


systematic_name: M11484
exact_source: GO:0031579
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031579
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M12305
exact_source: GO:0031581
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031581
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina. [GOC:dgh, PMID:15983403]


systematic_name: M23028
exact_source: GO:0031585
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031585
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel. [GOC:dph, GOC:mah, GOC:signaling]


systematic_name: M45844
exact_source: GO:0031590
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031590
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules. [GOC:mah, RNAmods:037]


systematic_name: M40402
exact_source: GO:0031622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of fever generation. [GOC:add]


systematic_name: M13598
exact_source: GO:0031623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. [GOC:bf, GOC:mah, GOC:signaling, PMID:15006537, PMID:19643732]


systematic_name: M45845
exact_source: GO:0031632
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031632
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane. [GOC:mah]


systematic_name: M23030
exact_source: GO:0031639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide. [PMID:9548733]


systematic_name: M11417
exact_source: GO:0031641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. [GOC:mah]


systematic_name: M23032
exact_source: GO:0031642
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031642
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. [GOC:mah]


systematic_name: M16608
exact_source: GO:0031643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. [GOC:mah]


systematic_name: M13921
exact_source: GO:0031644
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031644
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M11186
exact_source: GO:0031645
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031645
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M13905
exact_source: GO:0031646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a neurophysiological process. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M13931
exact_source: GO:0031647
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031647
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M12462
exact_source: GO:0031648
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031648
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. [GOC:mah]


systematic_name: M23033
exact_source: GO:0031649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any homeostatic process in which an organism produces heat, thereby raising its internal temperature. [GOC:mah]


systematic_name: M23034
exact_source: GO:0031652
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031652
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of heat generation. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M14323
exact_source: GO:0031663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. [GOC:mah, GOC:signaling, PMID:15379975]


systematic_name: M13762
exact_source: GO:0031664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. [GOC:mah]


systematic_name: M23035
exact_source: GO:0031665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. [GOC:mah]


systematic_name: M23036
exact_source: GO:0031666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. [GOC:mah]


systematic_name: M48411
exact_source: GO:0031667
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031667
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. [GOC:mah]


systematic_name: M48412
exact_source: GO:0031669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. [GOC:mah]


systematic_name: M14078
exact_source: GO:0031670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. [GOC:mah]


systematic_name: M23037
exact_source: GO:0031848
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031848
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse. [GOC:mah]


systematic_name: M23039
exact_source: GO:0031915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers. [GOC:mah]


