# gene_set_details

systematic_name: M14826
exact_source: GO:0031929
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031929
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. [PMID:12372295]


systematic_name: M23042
exact_source: GO:0031943
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031943
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. [GOC:mah]


systematic_name: M23043
exact_source: GO:0031944
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031944
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. [GOC:mah]


systematic_name: M23044
exact_source: GO:0031946
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031946
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. [GOC:mah]


systematic_name: M14909
exact_source: GO:0031952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues. [GOC:mah]


systematic_name: M10366
exact_source: GO:0031953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues. [GOC:mah]


systematic_name: M13383
exact_source: GO:0031954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues. [GOC:mah]


systematic_name: M23045
exact_source: GO:0031958
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031958
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by corticosteroid binding to its nuclear receptor inside the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, PMID:11027914, PMID:12606724]


systematic_name: M10764
exact_source: GO:0031960
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031960
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. [GOC:mah, PMID:11027914]


systematic_name: M23046
exact_source: GO:0031987
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031987
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. [GOC:mah]


systematic_name: M23047
exact_source: GO:0031999
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0031999
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation. [GOC:mah]


systematic_name: M23048
exact_source: GO:0032000
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032000
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation. [GOC:mah]


systematic_name: M13058
exact_source: GO:0032007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling. [GOC:mah]


systematic_name: M23049
exact_source: GO:0032011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the ARF subfamily relays a signal. [GOC:mah]


systematic_name: M12237
exact_source: GO:0032024
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032024
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. [GOC:mah]


systematic_name: M15970
exact_source: GO:0032025
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032025
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion (Co2+) stimulus. [GOC:mah]


systematic_name: M12099
exact_source: GO:0032026
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032026
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. [GOC:mah]


systematic_name: M14807
exact_source: GO:0032048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. [GOC:mah]


systematic_name: M34125
exact_source: GO:0032049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. [GOC:mah]


systematic_name: M42726
exact_source: GO:0032053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum). [GOC:cilia, GOC:dph, GOC:jl, GOC:krc, GOC:mah, PMID:9889124]


systematic_name: M23052
exact_source: GO:0032056
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032056
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. [GOC:mah]


systematic_name: M23053
exact_source: GO:0032060
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032060
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)]


systematic_name: M11879
exact_source: GO:0032069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. [GOC:mah]


systematic_name: M23054
exact_source: GO:0032070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. [GOC:mah]


systematic_name: M23055
exact_source: GO:0032071
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032071
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. [GOC:mah]


systematic_name: M23056
exact_source: GO:0032074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids. [GOC:mah]


systematic_name: M15465
exact_source: GO:0032075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. [GOC:mah]


systematic_name: M23057
exact_source: GO:0032077
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032077
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. [GOC:mah]


systematic_name: M12742
exact_source: GO:0032088
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032088
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. [GOC:dph, GOC:rl, GOC:tb]


systematic_name: M12295
exact_source: GO:0032091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. [GOC:mah]


systematic_name: M11257
exact_source: GO:0032094
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032094
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat. [GOC:add, ISBN:0721601464]


systematic_name: M13051
exact_source: GO:0032095
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032095
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a response to a food stimulus. [GOC:add]


systematic_name: M14548
exact_source: GO:0032101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a response to an external stimulus. [GOC:mah]


systematic_name: M16887
exact_source: GO:0032102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. [GOC:mah]


systematic_name: M12127
exact_source: GO:0032103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of a response to an external stimulus. [GOC:mah]


systematic_name: M48413
exact_source: GO:0032107
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032107
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a response to nutrient levels. [GOC:mah]


systematic_name: M48414
exact_source: GO:0032108
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032108
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels. [GOC:mah]


systematic_name: M23059
exact_source: GO:0032196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site. [ISBN:1555812090, PMID:14682279, PMID:25893143]


systematic_name: M11260
exact_source: GO:0032200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M23061
exact_source: GO:0032201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication. [GOC:BHF, GOC:BHF_telomere, GOC:rl, GOC:vw, PMID:16598261]


systematic_name: M12223
exact_source: GO:0032204
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032204
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. [GOC:mah]


systematic_name: M15180
exact_source: GO:0032205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. [GOC:mah]


systematic_name: M14393
exact_source: GO:0032206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. [GOC:mah]


systematic_name: M10472
exact_source: GO:0032211
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032211
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. [GOC:mah]


systematic_name: M29143
exact_source: GO:0032218
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032218
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins. [GOC:rn, PMID:16204239]


systematic_name: M23062
exact_source: GO:0032222
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032222
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. [GOC:mah]


systematic_name: M45113
exact_source: GO:0032224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. [GOC:mah]


systematic_name: M16908
exact_source: GO:0032225
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032225
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. [GOC:mah]


systematic_name: M15100
exact_source: GO:0032228
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032228
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). [GOC:mah]


systematic_name: M23064
exact_source: GO:0032229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). [GOC:mah]


systematic_name: M16438
exact_source: GO:0032230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). [GOC:mah]


systematic_name: M14318
exact_source: GO:0032231
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032231
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. [GOC:mah]


systematic_name: M12994
exact_source: GO:0032232
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032232
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. [GOC:mah]


systematic_name: M15855
exact_source: GO:0032233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. [GOC:mah]


systematic_name: M46765
exact_source: GO:0032238
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032238
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M11708
exact_source: GO:0032239
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032239
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M23066
exact_source: GO:0032241
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032241
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M23067
exact_source: GO:0032252
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032252
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. [GOC:mah]


systematic_name: M23068
exact_source: GO:0032261
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032261
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis. [GOC:jp]


systematic_name: M42727
exact_source: GO:0032263
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032263
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis. [GOC:mah]


systematic_name: M42728
exact_source: GO:0032264
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032264
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis. [GOC:mah]


systematic_name: M10309
exact_source: GO:0032271
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032271
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the process of creating protein polymers. [GOC:mah]


systematic_name: M10892
exact_source: GO:0032272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. [GOC:mah]


systematic_name: M16100
exact_source: GO:0032273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. [GOC:mah]


systematic_name: M23070
exact_source: GO:0032274
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032274
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. [GOC:mah, ISBN:0721662544]


systematic_name: M23071
exact_source: GO:0032275
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032275
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. [ISBN:0198506732]


systematic_name: M16612
exact_source: GO:0032276
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032276
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. [GOC:mah]


systematic_name: M23072
exact_source: GO:0032277
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032277
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. [GOC:mah]


systematic_name: M23073
exact_source: GO:0032278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. [GOC:mah]


systematic_name: M29144
exact_source: GO:0032286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the structure and material content of mature central nervous system myelin is kept in a functional state. [GOC:dgh]


systematic_name: M23074
exact_source: GO:0032287
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032287
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state. [GOC:dgh]


systematic_name: M14856
exact_source: GO:0032288
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032288
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. [GOC:dgh, GOC:dph, GOC:tb]


systematic_name: M40404
exact_source: GO:0032289
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032289
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. [GOC:dgh]


systematic_name: M12986
exact_source: GO:0032291
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032291
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. [GOC:dgh]


systematic_name: M48415
exact_source: GO:0032292
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032292
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. [GOC:dgh]


systematic_name: M10374
exact_source: GO:0032303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell. [GOC:mah]


systematic_name: M10560
exact_source: GO:0032306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell. [GOC:mah]


systematic_name: M45846
exact_source: GO:0032309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue. [GOC:mah]


systematic_name: M45847
exact_source: GO:0032310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue. [GOC:mah]


systematic_name: M23076
exact_source: GO:0032328
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032328
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M23077
exact_source: GO:0032329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M16573
exact_source: GO:0032331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. [GOC:mah]


systematic_name: M16272
exact_source: GO:0032332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. [GOC:mah]


systematic_name: M23078
exact_source: GO:0032344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. [GOC:mah]


systematic_name: M15585
exact_source: GO:0032350
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032350
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. [GOC:mah]


systematic_name: M23079
exact_source: GO:0032351
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032351
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. [GOC:mah]


systematic_name: M11648
exact_source: GO:0032352
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032352
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. [GOC:mah]


systematic_name: M42729
exact_source: GO:0032353
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032353
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. [GOC:ai]


systematic_name: M13287
exact_source: GO:0032354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. [GOC:mah]


systematic_name: M10509
exact_source: GO:0032355
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032355
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. [GOC:mah, ISBN:0911910123]


systematic_name: M23080
exact_source: GO:0032364
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032364
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell. [GOC:rph]


systematic_name: M13620
exact_source: GO:0032368
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032368
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M14419
exact_source: GO:0032369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M11731
exact_source: GO:0032370
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032370
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M14231
exact_source: GO:0032371
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032371
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M15259
exact_source: GO:0032372
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032372
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M11339
exact_source: GO:0032373
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032373
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M23082
exact_source: GO:0032377
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032377
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. [GOC:mah]


systematic_name: M48416
exact_source: GO:0032378
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032378
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. [GOC:mah]


systematic_name: M48417
exact_source: GO:0032379
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032379
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. [GOC:mah]


systematic_name: M16149
exact_source: GO:0032386
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032386
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. [GOC:mah]


systematic_name: M16766
exact_source: GO:0032387
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032387
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. [GOC:mah]


systematic_name: M11997
exact_source: GO:0032388
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032388
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. [GOC:mah]


systematic_name: M45115
exact_source: GO:0032417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). [GOC:mah]


systematic_name: M10362
exact_source: GO:0032434
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032434
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. [GOC:mah]


systematic_name: M23086
exact_source: GO:0032435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. [GOC:mah]


systematic_name: M40406
exact_source: GO:0032436
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032436
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. [GOC:mah]


systematic_name: M3309
exact_source: GO:0032446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein. [GOC:mah]


systematic_name: M14656
exact_source: GO:0032456
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032456
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. [PMID:16473635, PMID:23563491]


systematic_name: M13390
exact_source: GO:0032465
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032465
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells. [GOC:mah]


systematic_name: M23090
exact_source: GO:0032466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. [GOC:mah]


systematic_name: M13553
exact_source: GO:0032467
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032467
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells. [GOC:mah]


systematic_name: M14124
exact_source: GO:0032469
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032469
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings. [GOC:mah]


systematic_name: M23091
exact_source: GO:0032471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the concentration of calcium ions in the endoplasmic reticulum. [GOC:mah]


systematic_name: M11365
exact_source: GO:0032480
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032480
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. [GOC:add, GOC:mah]


systematic_name: M10589
exact_source: GO:0032481
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032481
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. [GOC:add, GOC:mah]


systematic_name: M23092
exact_source: GO:0032482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Rab subfamily relays a signal. [GOC:mah]


systematic_name: M34128
exact_source: GO:0032483
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032483
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of Rab protein signal transduction. [GOC:mah]


systematic_name: M23093
exact_source: GO:0032486
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032486
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Rap subfamily relays a signal. [GOC:mah]


systematic_name: M8454
exact_source: GO:0032488
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032488
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal. [GOC:mah, PMID:18558478]


systematic_name: M23095
exact_source: GO:0032489
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032489
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction. [GOC:mah]


systematic_name: M13529
exact_source: GO:0032490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal. [GOC:add, GOC:rl]


systematic_name: M23096
exact_source: GO:0032493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus. [GOC:add, PMID:12077222]


systematic_name: M23097
exact_source: GO:0032494
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032494
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. [GOC:add, ISBN:0721601464]


systematic_name: M11624
exact_source: GO:0032495
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032495
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. [GOC:add]


systematic_name: M46767
exact_source: GO:0032497
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032497
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. [GOC:add, PMID:15998797]


systematic_name: M11663
exact_source: GO:0032506
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032506
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells). [GOC:bf, GOC:isa_complete, GOC:mah]


systematic_name: M23098
exact_source: GO:0032507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. [GOC:isa_complete, GOC:mah]


systematic_name: M48418
exact_source: GO:0032509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment. [GOC:mah, PMID:12461556, PMID:16689637]


systematic_name: M23100
exact_source: GO:0032510
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032510
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome. [GOC:mah, PMID:12461556, PMID:16689637]


systematic_name: M23101
exact_source: GO:0032511
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032511
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole. [GOC:mah, PMID:12461556, PMID:16689637]


systematic_name: M23102
exact_source: GO:0032525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary. [GOC:bf, PMID:16326386, PMID:17360776]


systematic_name: M15050
exact_source: GO:0032526
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032526
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. [GOC:sl]


systematic_name: M15796
exact_source: GO:0032528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. [GOC:mah]


systematic_name: M14610
exact_source: GO:0032530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. [GOC:mah]


systematic_name: M11131
exact_source: GO:0032543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. [GOC:go_curators]


systematic_name: M14163
exact_source: GO:0032570
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032570
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. [GOC:sl]


systematic_name: M42734
exact_source: GO:0032571
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032571
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus. [GOC:sl]


systematic_name: M45117
exact_source: GO:0032596
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032596
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. [GOC:mah]


systematic_name: M23107
exact_source: GO:0032602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. [GOC:BHF, GOC:rl, ISBN:0198506732, PMID:12183377, Wikipedia:Chemokine]


systematic_name: M23108
exact_source: GO:0032604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah, ISBN:0198506732]


systematic_name: M23109
exact_source: GO:0032606
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032606
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834]


systematic_name: M23110
exact_source: GO:0032607
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032607
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah, PMID:15546383]


systematic_name: M23111
exact_source: GO:0032608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah, PMID:15546383]


systematic_name: M6428
exact_source: GO:0032609
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032609
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383]


systematic_name: M23112
exact_source: GO:0032610
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032610
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M11670
exact_source: GO:0032612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23114
exact_source: GO:0032613
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032613
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23115
exact_source: GO:0032615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23116
exact_source: GO:0032616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23117
exact_source: GO:0032620
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032620
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah, GOC:rv, Wikipedia:Interleukin_17]


systematic_name: M23118
exact_source: GO:0032621
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032621
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M6766
exact_source: GO:0032623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M34129
exact_source: GO:0032625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23120
exact_source: GO:0032627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23121
exact_source: GO:0032633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23122
exact_source: GO:0032634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23123
exact_source: GO:0032635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M18749
exact_source: GO:0032637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M14846
exact_source: GO:0032682
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032682
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production. [GOC:mah]


systematic_name: M23126
exact_source: GO:0032687
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032687
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production. [GOC:mah, PMID:15546383]


systematic_name: M23127
exact_source: GO:0032688
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032688
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production. [GOC:mah, PMID:15546383]


systematic_name: M12740
exact_source: GO:0032689
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032689
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383]


systematic_name: M34131
exact_source: GO:0032690
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032690
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production. [GOC:mah]


systematic_name: M48419
exact_source: GO:0032691
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032691
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. [GOC:mah]


systematic_name: M10557
exact_source: GO:0032692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. [GOC:mah]


systematic_name: M12756
exact_source: GO:0032693
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032693
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production. [GOC:mah]


systematic_name: M14223
exact_source: GO:0032695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production. [GOC:mah]


systematic_name: M23128
exact_source: GO:0032696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production. [GOC:mah]


systematic_name: M16185
exact_source: GO:0032700
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032700
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. [GOC:add, GOC:mah, PMID:16482511]


systematic_name: M40408
exact_source: GO:0032701
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032701
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production. [GOC:mah, PMID:23710316]


systematic_name: M16961
exact_source: GO:0032703
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032703
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production. [GOC:mah]


systematic_name: M42735
exact_source: GO:0032705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production. [GOC:mah]


systematic_name: M23129
exact_source: GO:0032713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production. [GOC:mah, PMID:29778524]


systematic_name: M23130
exact_source: GO:0032714
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032714
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production. [GOC:mah]


systematic_name: M11987
exact_source: GO:0032715
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032715
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production. [GOC:mah]


systematic_name: M14166
exact_source: GO:0032717
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032717
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production. [GOC:mah]


systematic_name: M13752
exact_source: GO:0032722
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032722
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of chemokine production. [GOC:mah]


systematic_name: M45118
exact_source: GO:0032725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production. [GOC:mah]


systematic_name: M15178
exact_source: GO:0032727
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032727
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interferon-alpha production. [GOC:mah, PMID:15546383]


systematic_name: M12719
exact_source: GO:0032728
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032728
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interferon-beta production. [GOC:mah, PMID:15546383]


systematic_name: M16043
exact_source: GO:0032729
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032729
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383]


systematic_name: M40409
exact_source: GO:0032730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production. [GOC:mah]


systematic_name: M46768
exact_source: GO:0032731
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032731
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production. [GOC:mah]


systematic_name: M13347
exact_source: GO:0032732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-1 production. [GOC:mah]


systematic_name: M16084
exact_source: GO:0032733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-10 production. [GOC:mah]


systematic_name: M12535
exact_source: GO:0032735
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032735
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-12 production. [GOC:mah]


systematic_name: M15396
exact_source: GO:0032736
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032736
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-13 production. [GOC:mah]


systematic_name: M14667
exact_source: GO:0032740
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032740
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines. [GOC:add, GOC:mah, PMID:16482511]


systematic_name: M42737
exact_source: GO:0032741
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032741
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-18 production. [GOC:mah]


systematic_name: M15337
exact_source: GO:0032743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-2 production. [GOC:mah]


systematic_name: M23133
exact_source: GO:0032747
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032747
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-23 production. [GOC:mah]


systematic_name: M14293
exact_source: GO:0032753
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032753
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-4 production. [GOC:mah]


systematic_name: M23134
exact_source: GO:0032754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-5 production. [GOC:mah]


systematic_name: M16211
exact_source: GO:0032755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. [GOC:mah]


systematic_name: M10636
exact_source: GO:0032757
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032757
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of interleukin-8 production. [GOC:mah]


systematic_name: M23138
exact_source: GO:0032782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. [GOC:ecd]


systematic_name: M16755
exact_source: GO:0032784
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032784
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. [GOC:mah, GOC:txnOH]


systematic_name: M15862
exact_source: GO:0032785
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032785
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. [GOC:mah, GOC:txnOH]


systematic_name: M16451
exact_source: GO:0032786
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032786
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase. [GOC:mah, GOC:txnOH]


systematic_name: M11574
exact_source: GO:0032787
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032787
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). [GOC:vk]


systematic_name: M23139
exact_source: GO:0032790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. [GOC:mah, GOC:vk]


systematic_name: M10875
exact_source: GO:0032793
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032793
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB. [GOC:dph, GOC:ecd, GOC:tb]


systematic_name: M16383
exact_source: GO:0032801
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032801
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:mah]


systematic_name: M23145
exact_source: GO:0032808
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032808
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. [GOC:ln]


systematic_name: M42738
exact_source: GO:0032811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine. [GOC:vk]


systematic_name: M12724
exact_source: GO:0032814
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032814
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of natural killer cell activation. [GOC:mah]


systematic_name: M23147
exact_source: GO:0032815
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032815
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. [GOC:mah]


systematic_name: M15133
exact_source: GO:0032816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of natural killer cell activation. [GOC:mah]


systematic_name: M45119
exact_source: GO:0032817
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032817
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of natural killer cell proliferation. [GOC:mah]


systematic_name: M23148
exact_source: GO:0032819
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032819
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation. [GOC:mah]


systematic_name: M23149
exact_source: GO:0032823
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032823
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of natural killer cell differentiation. [GOC:mah]


systematic_name: M23150
exact_source: GO:0032825
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032825
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation. [GOC:mah]


systematic_name: M40410
exact_source: GO:0032829
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032829
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells. [GOC:mah]


systematic_name: M13352
exact_source: GO:0032835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. [GOC:mah, GOC:mtg_kidney_jan10]


systematic_name: M23152
exact_source: GO:0032836
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032836
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. [GOC:sr]


systematic_name: M23153
exact_source: GO:0032847
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032847
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell. [GOC:mah]


systematic_name: M34134
exact_source: GO:0032849
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032849
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell. [GOC:mah]


systematic_name: M12725
exact_source: GO:0032868
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032868
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732]


systematic_name: M11784
exact_source: GO:0032869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. [GOC:mah, ISBN:0198506732]


systematic_name: M12601
exact_source: GO:0032870
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032870
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. [GOC:mah]


systematic_name: M14855
exact_source: GO:0032878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. [GOC:mah]


systematic_name: M14888
exact_source: GO:0032881
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032881
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. [GOC:mah]


systematic_name: M46769
exact_source: GO:0032885
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032885
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. [GOC:mah]


systematic_name: M10491
exact_source: GO:0032886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. [GOC:mah]


systematic_name: M10568
exact_source: GO:0032890
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032890
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M15391
exact_source: GO:0032891
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032891
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M16017
exact_source: GO:0032892
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032892
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M16672
exact_source: GO:0032897
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032897
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription. [GOC:mah]


systematic_name: M23155
exact_source: GO:0032905
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032905
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23156
exact_source: GO:0032906
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032906
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]


systematic_name: M23157
exact_source: GO:0032911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1. [GOC:mah]


systematic_name: M23158
exact_source: GO:0032914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1. [GOC:mah]


systematic_name: M11433
exact_source: GO:0032922
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032922
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours. [GOC:mah]


systematic_name: M14587
exact_source: GO:0032924
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032924
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:rl, GOC:signaling]


systematic_name: M16296
exact_source: GO:0032925
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032925
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway. [GOC:BHF, GOC:rl]


systematic_name: M23159
exact_source: GO:0032926
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032926
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway. [GOC:BHF, GOC:rl]


systematic_name: M23160
exact_source: GO:0032927
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032927
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway. [GOC:BHF, GOC:rl]


systematic_name: M11046
exact_source: GO:0032928
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032928
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell. [GOC:mah]


systematic_name: M29148
exact_source: GO:0032957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. [GOC:mah]


systematic_name: M23164
exact_source: GO:0032958
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032958
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. [GOC:mah]


systematic_name: M34136
exact_source: GO:0032959
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032959
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached. [GOC:mah]


systematic_name: M23167
exact_source: GO:0032963
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032963
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). [GOC:mah, ISBN:0198506732]


systematic_name: M23168
exact_source: GO:0032964
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032964
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). [GOC:mah, ISBN:0198506732]


systematic_name: M12696
exact_source: GO:0032968
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032968
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. [GOC:mah, GOC:txnOH]


systematic_name: M11956
exact_source: GO:0032970
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032970
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. [GOC:mah]


systematic_name: M48421
exact_source: GO:0032978
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032978
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side. [PMID:14739936, PMID:15473843]


systematic_name: M23172
exact_source: GO:0032984
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0032984
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The disaggregation of a protein-containing macromolecular complex into its constituent components. [GOC:mah]


systematic_name: M14006
exact_source: GO:0033004
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033004
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation. [GOC:mah]


systematic_name: M13599
exact_source: GO:0033005
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033005
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of mast cell activation. [GOC:mah]


systematic_name: M10912
exact_source: GO:0033006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response. [GOC:mah]


systematic_name: M13532
exact_source: GO:0033013
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033013
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. [GOC:mah]


systematic_name: M11455
exact_source: GO:0033014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. [GOC:mah]


systematic_name: M42741
exact_source: GO:0033015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. [GOC:mah]


systematic_name: M23176
exact_source: GO:0033028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093]


systematic_name: M40413
exact_source: GO:0033032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. [GOC:add, GOC:mtg_apoptosis]


systematic_name: M15111
exact_source: GO:0033033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. [GOC:add, GOC:mtg_apoptosis]


systematic_name: M23177
exact_source: GO:0033034
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033034
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. [GOC:add, GOC:mtg_apoptosis]


systematic_name: M5517
exact_source: GO:0033043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. [GOC:mah]


systematic_name: M15166
exact_source: GO:0033044
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033044
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. [GOC:mah]


systematic_name: M40414
exact_source: GO:0033047
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033047
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. [GOC:mah]


systematic_name: M23178
exact_source: GO:0033077
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033077
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. [GOC:add, ISBN:0781735149]


systematic_name: M23181
exact_source: GO:0033081
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033081
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. [GOC:add, GOC:mah]


systematic_name: M23182
exact_source: GO:0033085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. [GOC:add, GOC:mah]


systematic_name: M45120
exact_source: GO:0033087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. [GOC:add, GOC:mah]


systematic_name: M23184
exact_source: GO:0033089
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033089
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. [GOC:add, GOC:mah]


systematic_name: M34137
exact_source: GO:0033091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. [GOC:add, GOC:mah]


systematic_name: M11099
exact_source: GO:0033108
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033108
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex. [GOC:mah]


systematic_name: M11010
exact_source: GO:0033119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing. [GOC:mah]


systematic_name: M48422
exact_source: GO:0033131
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033131
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. [GOC:mah]


systematic_name: M12510
exact_source: GO:0033135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine. [GOC:mah]


systematic_name: M15438
exact_source: GO:0033137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine. [GOC:mah]


systematic_name: M16196
exact_source: GO:0033138
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033138
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine. [GOC:mah]


systematic_name: M11304
exact_source: GO:0033143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. [GOC:mah]


systematic_name: M12409
exact_source: GO:0033144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. [GOC:mah]


systematic_name: M11294
exact_source: GO:0033145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. [GOC:mah]


systematic_name: M12598
exact_source: GO:0033146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. [GOC:mah]


systematic_name: M11057
exact_source: GO:0033147
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033147
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway. [GOC:mah]


systematic_name: M16738
exact_source: GO:0033151
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033151
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). [GOC:add, ISBN:0781700221, ISBN:0781735149]


systematic_name: M29149
exact_source: GO:0033152
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033152
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. [GOC:add, ISBN:0781735149]


systematic_name: M13668
exact_source: GO:0033157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. [GOC:mah]


systematic_name: M14087
exact_source: GO:0033189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus. [GOC:sl]


systematic_name: M15279
exact_source: GO:0033194
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033194
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. [GOC:mah]


systematic_name: M14468
exact_source: GO:0033197
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033197
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus. [GOC:sl]


systematic_name: M13771
exact_source: GO:0033198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. [GOC:sl]


systematic_name: M23191
exact_source: GO:0033206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells. [GOC:mtg_cell_cycle]


systematic_name: M13837
exact_source: GO:0033209
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033209
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by tumor necrosis factor binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]


systematic_name: M23192
exact_source: GO:0033210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. [GOC:mah, GOC:signaling, GOC:yaf]


systematic_name: M23193
exact_source: GO:0033211
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033211
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by adiponectin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:20536390]


systematic_name: M23194
exact_source: GO:0033212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. [PMID:18622392, PMID:23192658, Wikipedia:Human_iron_metabolism]


systematic_name: M10843
exact_source: GO:0033233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein. [GOC:mah]


systematic_name: M23196
exact_source: GO:0033234
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033234
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein. [GOC:mah]


systematic_name: M15403
exact_source: GO:0033235
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033235
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein. [GOC:mah]


systematic_name: M11729
exact_source: GO:0033238
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033238
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. [GOC:mah]


systematic_name: M23197
exact_source: GO:0033239
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033239
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. [GOC:mah]


systematic_name: M10913
exact_source: GO:0033240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. [GOC:mah]


systematic_name: M11946
exact_source: GO:0033262
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033262
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. [GOC:mtg_cell_cycle]


systematic_name: M14836
exact_source: GO:0033273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. [GOC:sl]


systematic_name: M23199
exact_source: GO:0033278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. [GO_REF:0000021, GOC:dgf]


systematic_name: M14269
exact_source: GO:0033280
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033280
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. [GOC:sl]


systematic_name: M23200
exact_source: GO:0033292
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033292
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M23202
exact_source: GO:0033313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage. [GOC:mtg_cell_cycle]


systematic_name: M23203
exact_source: GO:0033314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A signal transduction process that contributes to a mitotic DNA replication checkpoint. [GOC:mtg_cell_cycle]


systematic_name: M12427
exact_source: GO:0033327
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033327
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. [GOC:ln, PMID:12050120]


systematic_name: M12103
exact_source: GO:0033344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. [GOC:sart]


systematic_name: M23204
exact_source: GO:0033353
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033353
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine. [GOC:mah, MetaCyc:PWY-5041]


systematic_name: M12532
exact_source: GO:0033363
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033363
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. [GOC:mah]


systematic_name: M14653
exact_source: GO:0033365
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033365
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within an organelle. [GOC:mah]


systematic_name: M48423
exact_source: GO:0033499
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033499
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose. [GOC:mah, MetaCyc:PWY-3821]


systematic_name: M14445
exact_source: GO:0033500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. [GOC:mah]


systematic_name: M23207
exact_source: GO:0033504
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033504
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the floor plate over time from its initial formation until its mature state. [GOC:dh]


systematic_name: M11873
exact_source: GO:0033539
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033539
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). [GOC:mah, MetaCyc:FAO-PWY, MetaCyc:PWY-5136]


systematic_name: M12385
exact_source: GO:0033540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). [GOC:mah, MetaCyc:PWY-5136]


systematic_name: M42745
exact_source: GO:0033554
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033554
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:mah]


systematic_name: M11861
exact_source: GO:0033555
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033555
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:mah]


systematic_name: M15568
exact_source: GO:0033559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. [GOC:mah]


systematic_name: M23209
exact_source: GO:0033564
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033564
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. [GOC:dph, GOC:kmv, GOC:tb]


systematic_name: M23210
exact_source: GO:0033572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mlg]


systematic_name: M12351
exact_source: GO:0033574
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033574
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. [GOC:sl]


systematic_name: M23212
exact_source: GO:0033591
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033591
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus. [GOC:sl]


systematic_name: M15838
exact_source: GO:0033598
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033598
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. [GOC:dph, GOC:mah]


systematic_name: M10463
exact_source: GO:0033599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation. [GOC:mah]


systematic_name: M23213
exact_source: GO:0033601
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033601
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation. [GOC:mah]


systematic_name: M42746
exact_source: GO:0033602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. [GOC:sl]


systematic_name: M23214
exact_source: GO:0033603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. [GOC:sl]


systematic_name: M14465
exact_source: GO:0033604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. [GOC:mah]


systematic_name: M13267
exact_source: GO:0033605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. [GOC:mah]


systematic_name: M42747
exact_source: GO:0033615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane. [GOC:mah]


systematic_name: M15212
exact_source: GO:0033619
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033619
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. [GOC:pde]


systematic_name: M23217
exact_source: GO:0033622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands. [GOC:add, PMID:12213832, PMID:14754902]


systematic_name: M23219
exact_source: GO:0033625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of integrin activation. [GOC:add]


systematic_name: M15495
exact_source: GO:0033627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. [GOC:add, PMID:12213832, PMID:14754902]


systematic_name: M13232
exact_source: GO:0033628
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033628
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin. [GOC:add]


systematic_name: M23220
exact_source: GO:0033629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin. [GOC:add]


systematic_name: M13399
exact_source: GO:0033630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin. [GOC:add]


systematic_name: M23221
exact_source: GO:0033631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits. [GOC:add, PMID:12213832, PMID:14754902]


systematic_name: M23222
exact_source: GO:0033632
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033632
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin. [GOC:add]


systematic_name: M23223
exact_source: GO:0033634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin. [GOC:add]


systematic_name: M10594
exact_source: GO:0033673
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033673
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:mah]


systematic_name: M42748
exact_source: GO:0033674
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033674
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:mah]


systematic_name: M42749
exact_source: GO:0033684
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033684
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. [GOC:mah]


systematic_name: M23225
exact_source: GO:0033687
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033687
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. [GOC:mah]


systematic_name: M23226
exact_source: GO:0033689
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033689
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. [GOC:mah]


systematic_name: M12213
exact_source: GO:0033762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. [GOC:sl]


systematic_name: M11301
exact_source: GO:0033865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. [GOC:mah, GOC:pde]


systematic_name: M14952
exact_source: GO:0033866
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033866
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. [GOC:mah, GOC:pde]


systematic_name: M23229
exact_source: GO:0033869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. [GOC:mah, GOC:pde]


systematic_name: M10353
exact_source: GO:0033962
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033962
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. [GOC:mah, PMID:17429074]


systematic_name: M14037
exact_source: GO:0033993
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0033993
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. [GOC:sl]


systematic_name: M23230
exact_source: GO:0034058
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034058
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The homotypic fusion of endocytic vesicles to form or add to an early endosome. [PMID:11964142, PMID:9422733]


systematic_name: M23231
exact_source: GO:0034063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule. [GOC:mah, PMID:17392519]


systematic_name: M14366
exact_source: GO:0034067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. [GOC:mah]


systematic_name: M46772
exact_source: GO:0034080
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034080
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres. [GOC:mah, GOC:vw, PMID:18158900, PMID:19217403, PMID:35422390]


systematic_name: M23232
exact_source: GO:0034085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase. [GOC:jh, GOC:mah, PMID:14623866]


systematic_name: M23233
exact_source: GO:0034086
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034086
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate. [GOC:mah, PMID:14623866]


systematic_name: M45849
exact_source: GO:0034087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle. [GOC:mah]


systematic_name: M23234
exact_source: GO:0034091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained. [GOC:mah, GOC:vw]


systematic_name: M23235
exact_source: GO:0034093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained. [GOC:mah, GOC:vw]


systematic_name: M15783
exact_source: GO:0034097
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034097
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. [GOC:sl]


systematic_name: M10976
exact_source: GO:0034101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process of regulating the production and elimination of erythrocytes within an organism. [GOC:add, PMID:10694114, PMID:14754397]


systematic_name: M12214
exact_source: GO:0034104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. [GOC:add]


systematic_name: M13871
exact_source: GO:0034105
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034105
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of tissue remodeling. [GOC:add]


systematic_name: M14754
exact_source: GO:0034110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion. [GOC:add]


systematic_name: M16688
exact_source: GO:0034111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion. [GOC:add]


systematic_name: M23236
exact_source: GO:0034112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion. [GOC:add]


systematic_name: M10825
exact_source: GO:0034114
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034114
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion. [GOC:add]


systematic_name: M23237
exact_source: GO:0034116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion. [GOC:add]


systematic_name: M11931
exact_source: GO:0034121
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034121
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M11168
exact_source: GO:0034122
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034122
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23239
exact_source: GO:0034134
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034134
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to toll-like receptor 2. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23240
exact_source: GO:0034135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23241
exact_source: GO:0034136
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034136
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23242
exact_source: GO:0034137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23243
exact_source: GO:0034138
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034138
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23244
exact_source: GO:0034139
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034139
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M42750
exact_source: GO:0034141
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034141
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M46773
exact_source: GO:0034142
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034142
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to toll-like receptor 4. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M11084
exact_source: GO:0034143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23246
exact_source: GO:0034144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23247
exact_source: GO:0034145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23248
exact_source: GO:0034154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 7. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M34138
exact_source: GO:0034155
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034155
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M48424
exact_source: GO:0034157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M42751
exact_source: GO:0034158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 8. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M10707
exact_source: GO:0034162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 9. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23249
exact_source: GO:0034163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M48425
exact_source: GO:0034164
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034164
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M40416
exact_source: GO:0034165
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034165
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway. [GOC:add, PMID:16551253, PMID:17328678]


systematic_name: M23250
exact_source: GO:0034196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids. [GOC:BHF, GOC:rl]


systematic_name: M23253
exact_source: GO:0034214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits. [GOC:ecd]


systematic_name: M42753
exact_source: GO:0034220
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034220
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. [GOC:mah]


systematic_name: M23254
exact_source: GO:0034227
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034227
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition a sulfur atom to a nucleotide in a tRNA molecule. [GOC:mcc, PMID:12549933, PMID:14722066]


systematic_name: M23255
exact_source: GO:0034238
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034238
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell. [GOC:sl]


systematic_name: M42754
exact_source: GO:0034242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. [GOC:mah]


systematic_name: M14685
exact_source: GO:0034248
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034248
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. [GOC:mah]


systematic_name: M11639
exact_source: GO:0034249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. [GOC:mah]


systematic_name: M10803
exact_source: GO:0034250
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034250
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. [GOC:mah]


systematic_name: M15318
exact_source: GO:0034260
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034260
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops or reduces the rate of GTP hydrolysis by a GTPase. [GO_REF:0000058, GOC:mah, GOC:rb, GOC:TermGenie, PMID:16143306, PMID:24335649]


systematic_name: M23256
exact_source: GO:0034285
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034285
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus. [GOC:sart]


systematic_name: M16559
exact_source: GO:0034308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. [GOC:mah]


systematic_name: M23257
exact_source: GO:0034309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. [GOC:mah]


systematic_name: M23258
exact_source: GO:0034310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. [GOC:mah]


systematic_name: M13615
exact_source: GO:0034311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. [GOC:curators]


systematic_name: M34140
exact_source: GO:0034312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms. [GOC:mah]


systematic_name: M15218
exact_source: GO:0034314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins. [GOC:mah, PMID:16959963, PMID:18640983]


systematic_name: M13607
exact_source: GO:0034315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. [GOC:mah]


systematic_name: M23260
exact_source: GO:0034316
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034316
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins. [GOC:mah, PMID:16959963]


systematic_name: M14884
exact_source: GO:0034329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. [GOC:mah]


systematic_name: M12450
exact_source: GO:0034330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M23261
exact_source: GO:0034331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M15116
exact_source: GO:0034332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. [GOC:aruk, GOC:bc, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M12531
exact_source: GO:0034333
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034333
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. [GOC:aruk, GOC:bc, GOC:mah]


systematic_name: M23262
exact_source: GO:0034334
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034334
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments. [GOC:aruk, GOC:bc, GOC:mah]


systematic_name: M11098
exact_source: GO:0034340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16681834]


systematic_name: M15265
exact_source: GO:0034341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon. [GOC:add, ISBN:0126896631, PMID:15546383]


systematic_name: M45122
exact_source: GO:0034342
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034342
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far. [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557]


systematic_name: M42755
exact_source: GO:0034343
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034343
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far. [GOC:add, ISBN:0126896631, PMID:15546383, PMID:16734557]


systematic_name: M23263
exact_source: GO:0034349
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034349
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. [CL:0000125, GOC:mtg_apoptosis, GOC:sart]


systematic_name: M23264
exact_source: GO:0034350
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034350
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. [GOC:mah, GOC:mtg_apoptosis]


systematic_name: M48426
exact_source: GO:0034351
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034351
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. [GOC:mah, GOC:mtg_apoptosis]


systematic_name: M23266
exact_source: GO:0034356
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034356
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside. [PMID:17482543]


systematic_name: M23267
exact_source: GO:0034367
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034367
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex. [GOC:BHF, GOC:mah, GOC:mtg_mpo, GOC:rl]


systematic_name: M23268
exact_source: GO:0034370
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034370
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


systematic_name: M15401
exact_source: GO:0034374
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034374
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


systematic_name: M14745
exact_source: GO:0034375
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034375
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL. [GOC:BHF, GOC:expert_pt, GOC:mah, GOC:rl]


systematic_name: M23272
exact_source: GO:0034379
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034379
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle. [GOC:BHF, GOC:mah]


systematic_name: M23273
exact_source: GO:0034380
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034380
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle. [GOC:BHF, GOC:mah]


systematic_name: M12592
exact_source: GO:0034381
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034381
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:mah, GOC:tb]


systematic_name: M11765
exact_source: GO:0034383
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034383
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:mah]


systematic_name: M23274
exact_source: GO:0034384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:mah]


systematic_name: M23275
exact_source: GO:0034389
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034389
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle. [GOC:dph, GOC:jl, GOC:mah, PMID:18093937, PMID:18250201]


systematic_name: M23276
exact_source: GO:0034390
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034390
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl]


systematic_name: M23277
exact_source: GO:0034392
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034392
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]


systematic_name: M23278
exact_source: GO:0034393
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034393
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. [GOC:BHF, GOC:mtg_apoptosis, GOC:rl]


systematic_name: M14783
exact_source: GO:0034394
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034394
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane. [GOC:mah]


systematic_name: M45850
exact_source: GO:0034397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a telomere is transported to, and/or maintained in, a specific location. [GOC:mah, GOC:vw]


systematic_name: M45851
exact_source: GO:0034398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a telomere is maintained in a specific location at the nuclear periphery. [GOC:mah]


systematic_name: M23281
exact_source: GO:0034404
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034404
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. [GOC:mah]


systematic_name: M10752
exact_source: GO:0034405
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034405
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. [GOC:sl]


systematic_name: M15880
exact_source: GO:0034440
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034440
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. [GOC:BHF, GOC:mah]


systematic_name: M13894
exact_source: GO:0034446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate. [GOC:mah, GOC:pf, PMID:17050732]


systematic_name: M23284
exact_source: GO:0034447
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034447
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF, GOC:rl]


systematic_name: M48427
exact_source: GO:0034486
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034486
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a solute is transported from one side of the vacuolar membrane to the other. [GOC:mah]


systematic_name: M23288
exact_source: GO:0034497
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034497
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS). [GOC:rb]


systematic_name: M13155
exact_source: GO:0034502
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034502
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. [GOC:mah]


systematic_name: M16062
exact_source: GO:0034504
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034504
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein transports or maintains the localization of another protein to the nucleus. [GOC:ecd]


systematic_name: M11506
exact_source: GO:0034505
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034505
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. [GOC:mah, MP:0002817, MSH:D014074]


systematic_name: M16315
exact_source: GO:0034508
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034508
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere. [GOC:mah, GOC:vw]


systematic_name: M14535
exact_source: GO:0034587
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034587
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process leading to the generation of a functional piRNA. piRNAs (Piwi-associated RNAs) are a class of 24- to 30-nucleotide RNAs derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism. [GOC:kmv, PMID:23329111, PMID:24696457, PMID:34724117]


systematic_name: M45123
exact_source: GO:0034599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. [GOC:mah]


systematic_name: M13924
exact_source: GO:0034605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. [GOC:mah]


systematic_name: M16143
exact_source: GO:0034612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus. [GOC:mah]


systematic_name: M16581
exact_source: GO:0034614
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034614
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. [GOC:mah]


systematic_name: M16613
exact_source: GO:0034616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls. [GOC:ecd]


systematic_name: M40418
exact_source: GO:0034627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:imk, PMID:17161604]


systematic_name: M45853
exact_source: GO:0034635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M23293
exact_source: GO:0034638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. [GOC:jp]


systematic_name: M48428
exact_source: GO:0034643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of the mitochondrion to a specific location, by a process involving microtubules. [GOC:mah, PMID:12972644, PMID:15979253, PMID:16306220]


systematic_name: M10612
exact_source: GO:0034644
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034644
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. [GOC:mah]


systematic_name: M29153
exact_source: GO:0034650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. [GOC:BHF, GOC:mah, GOC:rl]


systematic_name: M42758
exact_source: GO:0034651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties. [GOC:BHF, GOC:mah, GOC:rl]


systematic_name: M23295
exact_source: GO:0034656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. [GOC:mah]


systematic_name: M12603
exact_source: GO:0034694
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034694
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. [GOC:BHF, GOC:vk]


systematic_name: M10616
exact_source: GO:0034695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. [GOC:BHF, GOC:vk]


systematic_name: M15965
exact_source: GO:0034698
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034698
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. [GOC:BHF, GOC:vk]


systematic_name: M42759
exact_source: GO:0034699
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034699
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. [GOC:BHF, GOC:vk]


systematic_name: M23298
exact_source: GO:0034728
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034728
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. [GOC:mah]


systematic_name: M23299
exact_source: GO:0034755
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034755
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah, PMID:11390404]


systematic_name: M23300
exact_source: GO:0034756
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034756
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M46774
exact_source: GO:0034759
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034759
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M16782
exact_source: GO:0034762
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034762
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


systematic_name: M10216
exact_source: GO:0034763
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034763
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


systematic_name: M11713
exact_source: GO:0034764
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034764
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. [GOC:mah]


systematic_name: M42761
exact_source: GO:0034765
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034765
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


systematic_name: M42762
exact_source: GO:0034766
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034766
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


systematic_name: M42763
exact_source: GO:0034767
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034767
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. [GOC:mah]


systematic_name: M16545
exact_source: GO:0034776
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034776
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. [GOC:BHF, GOC:mah, GOC:vk]


systematic_name: M14955
exact_source: GO:0034975
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034975
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation). [GOC:mah, GOC:vw]


systematic_name: M10844
exact_source: GO:0034976
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034976
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. [GOC:cjm, GOC:mah]


systematic_name: M23306
exact_source: GO:0034982
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034982
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. [GOC:curators]


systematic_name: M23307
exact_source: GO:0034983
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0034983
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of an acetyl group from an acetylated lysine residue in a peptide or protein. [GOC:BHF, GOC:mah]


systematic_name: M10312
exact_source: GO:0035019
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035019
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. [GOC:bf, ISBN:0582227089]


systematic_name: M12923
exact_source: GO:0035020
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035020
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of Rac protein signal transduction. [GOC:bf]


systematic_name: M48429
exact_source: GO:0035021
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035021
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction. [GOC:bf]


systematic_name: M40420
exact_source: GO:0035022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction. [GOC:bf]


systematic_name: M13862
exact_source: GO:0035023
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035023
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of Rho protein signal transduction. [GOC:bf]


systematic_name: M12850
exact_source: GO:0035024
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035024
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction. [GOC:bf]


systematic_name: M11062
exact_source: GO:0035025
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035025
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction. [GOC:bf]


systematic_name: M13217
exact_source: GO:0035036
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035036
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization. [GOC:bf]


systematic_name: M12452
exact_source: GO:0035050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. [GOC:go_curators]


systematic_name: M14538
exact_source: GO:0035051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. [GOC:bf]


systematic_name: M15673
exact_source: GO:0035082
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035082
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194]


systematic_name: M23309
exact_source: GO:0035092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication. [GOC:bf, PMID:11735001]


systematic_name: M14038
exact_source: GO:0035094
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035094
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. [GOC:bf, GOC:ef, ISBN:0198506732, ISBN:0582227089]


systematic_name: M23311
exact_source: GO:0035095
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035095
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus. [GOC:bf, ISBN:0198506732]


systematic_name: M23312
exact_source: GO:0035107
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035107
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. [ISBN:0582227089]


systematic_name: M23313
exact_source: GO:0035112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. [GOC:bf]


systematic_name: M29156
exact_source: GO:0035113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. [ISBN:0582227089]


systematic_name: M12566
exact_source: GO:0035115
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035115
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. [ISBN:0198612001]


systematic_name: M13437
exact_source: GO:0035116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal. [ISBN:0198612001]


systematic_name: M11468
exact_source: GO:0035136
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035136
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. [GOC:go_curators]


systematic_name: M10782
exact_source: GO:0035137
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035137
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the hindlimb are generated and organized. [GOC:go_curators]


systematic_name: M14377
exact_source: GO:0035148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. [GOC:bf]


systematic_name: M23314
exact_source: GO:0035150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes. [PMID:10887083]


systematic_name: M48430
exact_source: GO:0035166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stages of blood cell formation that take place after completion of embryonic development. [GOC:bf]


systematic_name: M45858
exact_source: GO:0035196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts. [GOC:aruk, GOC:bc, GOC:dph, GOC:rl, GOC:tb, PMID:15066275, PMID:15066283, PMID:23985560, PMID:28379604]


systematic_name: M23315
exact_source: GO:0035234
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035234
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. [PMID:12814944]


systematic_name: M45859
exact_source: GO:0035235
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035235
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:signaling, ISBN:0198506732]


systematic_name: M18329
exact_source: GO:0035239
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035239
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. [GOC:bf, PMID:14624839]


systematic_name: M15296
exact_source: GO:0035249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. [GOC:dos]


systematic_name: M13366
exact_source: GO:0035264
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035264
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The increase in size or mass of an entire multicellular organism, as opposed to cell growth. [GOC:bf, GOC:curators, GOC:dph, GOC:tb]


systematic_name: M13518
exact_source: GO:0035265
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035265
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. [GOC:bf, ISBN:0471245208, ISBN:0721662544]


systematic_name: M12862
exact_source: GO:0035269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage. [GOC:bf, PMID:9878797]


systematic_name: M15186
exact_source: GO:0035270
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035270
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. [GOC:bf, Wikipedia:Development_of_the_endocrine_system]


systematic_name: M13401
exact_source: GO:0035272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. [GOC:bf, Wikipedia:Exocrine_gland]


systematic_name: M45126
exact_source: GO:0035278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs. [PMID:14744438, PMID:15196554]


systematic_name: M45127
exact_source: GO:0035279
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035279
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. [GOC:dph, GOC:mtg_lung, PMID:14744438, PMID:15196554, PMID:21118121, PMID:23209154]


systematic_name: M13563
exact_source: GO:0035282
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035282
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. [PMID:10611687, PMID:9706689]


systematic_name: M45128
exact_source: GO:0035290
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035290
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. [PMID:1360402]


systematic_name: M2973
exact_source: GO:0035295
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035295
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. [PMID:12526790]


systematic_name: M14444
exact_source: GO:0035303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf]


systematic_name: M23319
exact_source: GO:0035304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein. [GOC:bf]


systematic_name: M14155
exact_source: GO:0035305
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035305
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf]


systematic_name: M16159
exact_source: GO:0035306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf]


systematic_name: M23320
exact_source: GO:0035307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein. [GOC:bf]


systematic_name: M23321
exact_source: GO:0035308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein. [GOC:bf]


systematic_name: M15499
exact_source: GO:0035313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis. [GOC:bf, PMID:15269788]


systematic_name: M14565
exact_source: GO:0035315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a hair cell. [GOC:bf]


systematic_name: M11445
exact_source: GO:0035329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cascade that starts with the activation of hippo (STK4/MST1 and STK3/MST2 in mammals and hpo kinase in Drosophila). Hippo then phosphorylates LATS1/2, which in turn phosphoylates the transcriptional co-activator YAP1 (yki in Drosophila), leading to its cytosolic retention and/or degradation. [PMID:17318211, PMID:18328423, PMID:36347846]


systematic_name: M23323
exact_source: GO:0035331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling. [GOC:bf]


systematic_name: M23325
exact_source: GO:0035335
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035335
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine. [GOC:bf]


systematic_name: M23326
exact_source: GO:0035336
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035336
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [ISBN:0198506732]


systematic_name: M12232
exact_source: GO:0035337
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035337
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. [ISBN:0198506732]


systematic_name: M23327
exact_source: GO:0035338
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035338
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. [ISBN:0198506732]


systematic_name: M46776
exact_source: GO:0035352
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035352
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH. [GOC:bf]


systematic_name: M23328
exact_source: GO:0035356
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035356
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of triglyceride within a cell. [GOC:BHF]


systematic_name: M23329
exact_source: GO:0035357
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035357
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes. [GOC:BHF, PMID:18221086]


systematic_name: M13315
exact_source: GO:0035358
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035358
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]


systematic_name: M23330
exact_source: GO:0035360
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035360
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]


systematic_name: M15448
exact_source: GO:0035384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol. [GOC:bf, http://encyclopedia.thefreedictionary.com/Thioester]


systematic_name: M10948
exact_source: GO:0035385
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035385
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a SLIT protein binding to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:signaling]


systematic_name: M15091
exact_source: GO:0035418
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035418
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. [GOC:bf]


systematic_name: M23335
exact_source: GO:0035425
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035425
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type. [GOC:bf, ISBN:3527303782]


systematic_name: M34146
exact_source: GO:0035426
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035426
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information between the extracellular matrix and a cell. [GOC:bf]


systematic_name: M23338
exact_source: GO:0035437
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035437
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum. [GOC:bf, GOC:vw]


systematic_name: M23340
exact_source: GO:0035442
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035442
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond. [GOC:vw]


systematic_name: M48431
exact_source: GO:0035443
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035443
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds. [GOC:vw]


systematic_name: M11929
exact_source: GO:0035455
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035455
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. [GOC:sl, PMID:11356686]


systematic_name: M11809
exact_source: GO:0035456
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035456
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. [GOC:sl, PMID:9561374]


systematic_name: M23341
exact_source: GO:0035457
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035457
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon. [GOC:sl]


systematic_name: M16666
exact_source: GO:0035458
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035458
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. [GOC:sl]


systematic_name: M23342
exact_source: GO:0035459
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035459
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle. [GOC:bf, GOC:lb]


systematic_name: M23343
exact_source: GO:0035461
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035461
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. [GOC:bf]


systematic_name: M23344
exact_source: GO:0035469
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035469
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism. [GOC:dgh, PMID:12702646]


systematic_name: M29158
exact_source: GO:0035470
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035470
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. [GOC:rph]


systematic_name: M23345
exact_source: GO:0035482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum. [GOC:cy, ISBN:9781416032458, PMID:16139031]


systematic_name: M23347
exact_source: GO:0035493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. [GOC:rb, PMID:10872468]


systematic_name: M23348
exact_source: GO:0035502
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035502
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M23349
exact_source: GO:0035507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity. [GOC:bf, GOC:go_curators]


systematic_name: M23350
exact_source: GO:0035509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity. [GOC:bf, GOC:go_curators]


systematic_name: M23353
exact_source: GO:0035519
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035519
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation. [PMID:17028573]


systematic_name: M23355
exact_source: GO:0035523
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035523
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein. [GOC:bf]


systematic_name: M23356
exact_source: GO:0035524
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035524
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore. [GOC:vw]


systematic_name: M23357
exact_source: GO:0035542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. [GOC:rb]


systematic_name: M11819
exact_source: GO:0035561
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035561
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. [GOC:bf, PMID:20404130]


systematic_name: M23360
exact_source: GO:0035563
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035563
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. [GOC:bf, PMID:20404130]


systematic_name: M10871
exact_source: GO:0035567
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035567
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via effectors other than beta-catenin. [PMID:37804416]


systematic_name: M23361
exact_source: GO:0035581
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035581
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor. [GOC:BHF, GOC:signaling]


systematic_name: M42766
exact_source: GO:0035582
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035582
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins. [GOC:BHF, PMID:20855508]


systematic_name: M10205
exact_source: GO:0035588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:BHF, PMID:9755289]


systematic_name: M10348
exact_source: GO:0035589
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035589
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:BHF, PMID:9755289]


systematic_name: M14531
exact_source: GO:0035590
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035590
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, PMID:9755289]


systematic_name: M23362
exact_source: GO:0035608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation. [GOC:sp, PMID:21074048]


systematic_name: M23364
exact_source: GO:0035610
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035610
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation. [GOC:sp, PMID:21074048]


systematic_name: M23365
exact_source: GO:0035617
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035617
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The disaggregation of a stress granule into its constituent protein and RNA parts. [GOC:BHF, PMID:19825938]


systematic_name: M23367
exact_source: GO:0035627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid. [GOC:bf, GOC:sart]


systematic_name: M23368
exact_source: GO:0035630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. [GOC:bf, GOC:BHF]


systematic_name: M34149
exact_source: GO:0035633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation. [GOC:aruk, GOC:bc, GOC:bf, GOC:sl, PMID:20080302, PMID:30280653]


systematic_name: M23369
exact_source: GO:0035634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones. [GOC:yaf, Wikipedia:Stilbenoid]


systematic_name: M23370
exact_source: GO:0035635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. [GOC:bf, PMID:21187937]


systematic_name: M15041
exact_source: GO:0035640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific behavior of an organism in response to a novel environment or stimulus. [GOC:BHF, GOC:pr, PMID:11682103, PMID:9767169]


systematic_name: M16658
exact_source: GO:0035641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific movement from place to place of an organism in response to a novel environment. [GOC:sart, PMID:17151232]


systematic_name: M45129
exact_source: GO:0035652
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035652
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle. [GOC:lb, PMID:16162817]


systematic_name: M23371
exact_source: GO:0035655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-18 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:BHF, GOC:signaling]


systematic_name: M42767
exact_source: GO:0035666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response. [GOC:BHF, PMID:12855817]


systematic_name: M23372
exact_source: GO:0035694
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035694
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. [GOC:sp, PMID:21264221, PMID:21264228]


systematic_name: M23373
exact_source: GO:0035696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of a monocyte from the blood vessels into the surrounding tissue. [CL:0000576, GOC:BHF, PMID:10657654]


systematic_name: M23374
exact_source: GO:0035701
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035701
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. [CL:0000037, GOC:BHF, PMID:20234092]


systematic_name: M12491
exact_source: GO:0035710
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035710
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [CL:0000624, GOC:BHF]


systematic_name: M45130
exact_source: GO:0035720
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035720
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins. [GOC:BHF, GOC:cilia, PMID:17895364]


systematic_name: M23375
exact_source: GO:0035721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins. [GOC:BHF, GOC:cilia]


systematic_name: M46777
exact_source: GO:0035722
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035722
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-12 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:signaling]


systematic_name: M10768
exact_source: GO:0035725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:vw]


systematic_name: M23376
exact_source: GO:0035726
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035726
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage. [CL:0000049, GOC:BHF]


systematic_name: M13705
exact_source: GO:0035728
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035728
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus. [GOC:bf]


systematic_name: M23377
exact_source: GO:0035733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor. [CL:0000632, GOC:bf]


systematic_name: M23378
exact_source: GO:0035735
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035735
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2]


systematic_name: M23379
exact_source: GO:0035739
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035739
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The expansion of a CD4-positive, alpha-beta T cell population by cell division. [CL:0000624, GOC:BHF]


systematic_name: M23380
exact_source: GO:0035740
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035740
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The expansion of a CD8-positive, alpha-beta T cell population by cell division. [CL:0000625, GOC:BHF]


systematic_name: M23381
exact_source: GO:0035743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell. [CL:0000624, GOC:BHF]


systematic_name: M23384
exact_source: GO:0035747
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035747
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). [CL:0000623, GOC:BHF]


systematic_name: M23385
exact_source: GO:0035751
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035751
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. [GOC:rph]


systematic_name: M23386
exact_source: GO:0035754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). [CL:0000236, GOC:BHF]


systematic_name: M23387
exact_source: GO:0035767
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035767
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). [CL:0000115, GOC:BHF]


systematic_name: M23388
exact_source: GO:0035771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-4 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:signaling]


systematic_name: M23389
exact_source: GO:0035773
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035773
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. [GOC:bf, GOC:yaf, PMID:8492079]


systematic_name: M16330
exact_source: GO:0035774
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035774
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. [GOC:bf, GOC:yaf]


systematic_name: M23390
exact_source: GO:0035787
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035787
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]


systematic_name: M42769
exact_source: GO:0035788
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035788
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf]


systematic_name: M23391
exact_source: GO:0035790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated a ligand binding to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:yaf, PMID:10372961]


systematic_name: M23392
exact_source: GO:0035791
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035791
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:signaling, GOC:yaf, PMID:10372961]


systematic_name: M46778
exact_source: GO:0035794
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035794
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. [GOC:bf, PMID:12546810]


systematic_name: M13416
exact_source: GO:0035809
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035809
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the amount of urine excreted from the body over a unit of time. [GOC:mtg_25march11, GOC:yaf]


systematic_name: M13749
exact_source: GO:0035810
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035810
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the amount of urine excreted from the body over a unit of time. [GOC:mtg_25march11, GOC:yaf]


systematic_name: M48432
exact_source: GO:0035811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the amount of urine excreted from the body over a unit of time. [GOC:mtg_25march11, GOC:yaf]


systematic_name: M23394
exact_source: GO:0035812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The elimination of sodium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. [GOC:mtg_25march11, GOC:yaf, PMID:25287933]


systematic_name: M46779
exact_source: GO:0035813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the amount of sodium excreted in urine over a unit of time. [GOC:mtg_25march11, GOC:yaf]


systematic_name: M11347
exact_source: GO:0035821
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035821
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an organism effects a change in the structure or processes of another organism. [GOC:bf]


systematic_name: M23395
exact_source: GO:0035825
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035825
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules. [GOC:mah, PMID:11139492, PMID:17304215]


systematic_name: M23396
exact_source: GO:0035845
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035845
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. [ISBN:0824072820, PMID:14507858]


systematic_name: M15205
exact_source: GO:0035850
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035850
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236]


systematic_name: M13503
exact_source: GO:0035855
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035855
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. [CL:0000556, GOC:BHF, GOC:vk]


systematic_name: M23397
exact_source: GO:0035860
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035860
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor. [GOC:yaf, PMID:12953054, PMID:29245123]


systematic_name: M11214
exact_source: GO:0035864
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035864
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. [GOC:yaf]


systematic_name: M23398
exact_source: GO:0035865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus. [GOC:yaf]


systematic_name: M23399
exact_source: GO:0035871
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035871
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein. [GOC:sp, PMID:21596315]


systematic_name: M10860
exact_source: GO:0035872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. [GOC:sj, PMID:18280719, PMID:32838963, PMID:36973360]


systematic_name: M34151
exact_source: GO:0035873
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035873
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices. [GOC:mcc, ISBN:0198506732]


systematic_name: M23400
exact_source: GO:0035878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. [GOC:bf, ISBN:0323025781, UBERON:0001705, Wikipedia:Nail_(anatomy)]


systematic_name: M23401
exact_source: GO:0035881
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035881
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. [CL:0000561, GOC:bf]


systematic_name: M14305
exact_source: GO:0035883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. [CL:0000164, GOC:bf]


systematic_name: M11408
exact_source: GO:0035886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. [GOC:sl, PMID:16151017, PMID:18267954]


systematic_name: M10626
exact_source: GO:0035902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile. [GOC:bf, PMID:17683801, PMID:19893991]


systematic_name: M12034
exact_source: GO:0035904
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035904
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]


systematic_name: M23403
exact_source: GO:0035905
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035905
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta]


systematic_name: M23404
exact_source: GO:0035907
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035907
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]


systematic_name: M16151
exact_source: GO:0035909
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035909
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta]


systematic_name: M34152
exact_source: GO:0035912
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035912
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014]


systematic_name: M15486
exact_source: GO:0035914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. [CL:0000188, GOC:BHF, GOC:vk]


systematic_name: M16443
exact_source: GO:0035924
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035924
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus. [GOC:BHF, GOC:rl, PMID:18440775]


systematic_name: M23406
exact_source: GO:0035927
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035927
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix. [GOC:ans, PMID:20691904]


systematic_name: M29161
exact_source: GO:0035931
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035931
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. [GOC:sl]


systematic_name: M23410
exact_source: GO:0035933
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035933
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. [GOC:sl]


systematic_name: M45131
exact_source: GO:0035934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. [GOC:sl]


systematic_name: M48433
exact_source: GO:0035962
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035962
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus. [GOC:sjw, PMID:20100461]


systematic_name: M23415
exact_source: GO:0035964
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035964
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle. [GOC:br, PMID:10052452, PMID:17041781]


systematic_name: M23416
exact_source: GO:0035965
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035965
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids. [GOC:bf, GOC:rb, PMID:19244244]


systematic_name: M16675
exact_source: GO:0035966
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035966
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. [GOC:bf]


systematic_name: M11845
exact_source: GO:0035967
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035967
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure. [GOC:bf]


systematic_name: M23417
exact_source: GO:0035970
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035970
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine. [GOC:bf]


systematic_name: M23418
exact_source: GO:0035973
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035973
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective degradation of protein aggregates by macroautophagy. [GOC:autophagy, GOC:kmv, PMID:18508269, PMID:25062811]


systematic_name: M23420
exact_source: GO:0035988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage. [CL:0000138, GOC:yaf, PMID:21484705]


systematic_name: M23421
exact_source: GO:0035989
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035989
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. [GOC:yaf, PMID:21412429, UBERON:0000043]


systematic_name: M10522
exact_source: GO:0035994
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035994
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length. [GOC:BHF, GOC:vk, PMID:14583192]


systematic_name: M40421
exact_source: GO:0035995
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035995
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal. [PMID:14583192]


systematic_name: M14912
exact_source: GO:0035999
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0035999
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules. [GOC:yaf, PMID:1825999]


systematic_name: M23422
exact_source: GO:0036005
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036005
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. [GOC:yaf, PMID:14687666]


systematic_name: M45132
exact_source: GO:0036006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus. [GOC:yaf, PMID:14687666]


systematic_name: M23423
exact_source: GO:0036010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within an endosome. [GOC:yaf]


systematic_name: M23424
exact_source: GO:0036015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus. [GOC:yaf]


systematic_name: M23425
exact_source: GO:0036017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis. [GOC:yaf]


systematic_name: M42771
exact_source: GO:0036022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. [GOC:bf]


systematic_name: M23427
exact_source: GO:0036037
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036037
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [CL:0000625, GOC:yaf]


systematic_name: M48434
exact_source: GO:0036066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage. [GOC:sart, PMID:19948734]


systematic_name: M23428
exact_source: GO:0036072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. [GO_REF:0000034]


systematic_name: M11955
exact_source: GO:0036075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. [GO_REF:0000034]


systematic_name: M23429
exact_source: GO:0036089
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036089
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell. [GOC:ans, PMID:15811947, PMID:20687468, PMID:2192590]


systematic_name: M11710
exact_source: GO:0036092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. [GOC:al, GOC:vw]


systematic_name: M23431
exact_source: GO:0036093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. [CL:0000586, GOC:kmv]


systematic_name: M45133
exact_source: GO:0036100
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036100
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. [GOC:yaf]


systematic_name: M46780
exact_source: GO:0036102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents. [GOC:bf]


systematic_name: M13605
exact_source: GO:0036109
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036109
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. [PMID:15538555]


systematic_name: M42772
exact_source: GO:0036112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons. [GOC:pm]


systematic_name: M42773
exact_source: GO:0036115
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036115
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group. [PMID:10578051]


systematic_name: M13193
exact_source: GO:0036119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus. [GOC:yaf]


systematic_name: M45134
exact_source: GO:0036135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. [CL:0002573, PMID:20335460]


systematic_name: M15445
exact_source: GO:0036148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains. [GOC:mw, PMID:15485873, PMID:18458083]


systematic_name: M16512
exact_source: GO:0036149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains. [GOC:mw, PMID:18094042, PMID:18772128]


systematic_name: M10047
exact_source: GO:0036150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains. [GOC:mw, PMID:18287005, PMID:18458083]


systematic_name: M16020
exact_source: GO:0036151
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036151
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains. [GOC:mw, PMID:18195019, PMID:18458083]


systematic_name: M15963
exact_source: GO:0036152
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036152
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains. [GOC:mw, PMID:18287005, PMID:18458083]


systematic_name: M13644
exact_source: GO:0036158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. [GOC:BHF, GOC:vk, PMID:19944400]


systematic_name: M12111
exact_source: GO:0036159
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036159
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. [GOC:BHF, GOC:vk, PMID:19944400]


systematic_name: M23436
exact_source: GO:0036166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues. [GOC:bf, GOC:di, PMID:12443899, PMID:22406749, PMID:8456504, Wikipedia:Phenotypic_switching]


systematic_name: M42774
exact_source: GO:0036230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [CL:0000094, GOC:nhn]


systematic_name: M13034
exact_source: GO:0036257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm. [GOC:sart, PMID:11566881]


systematic_name: M13443
exact_source: GO:0036260
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036260
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts. [GOC:bf, GOC:krc, GOC:mah, PMID:18775984, PMID:27383794, PMID:29681497, PMID:30353673]


systematic_name: M45135
exact_source: GO:0036261
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036261
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation. [GOC:bf, GOC:BHF, GOC:krc, GOC:mah, GOC:rl, PMID:11983179, PMID:18775984]


systematic_name: M23437
exact_source: GO:0036265
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036265
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule. [GOC:BHF, GOC:rl]


systematic_name: M23438
exact_source: GO:0036289
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036289
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein. [GOC:pm]


systematic_name: M23439
exact_source: GO:0036295
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036295
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. [GOC:al]


systematic_name: M12574
exact_source: GO:0036296
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036296
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen. [GOC:al]


systematic_name: M13951
exact_source: GO:0036297
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036297
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication. [GOC:vw, PMID:16464006, PMID:22064477]


systematic_name: M23440
exact_source: GO:0036301
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036301
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF, GOC:vk]


systematic_name: M23441
exact_source: GO:0036302
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036302
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. [GOC:BHF, GOC:gr, PMID:14701881, UBERON:0002087, ZFA:0001315]


systematic_name: M14470
exact_source: GO:0036303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. [GOC:BHF, GOC:gr, PMID:18093989]


systematic_name: M45136
exact_source: GO:0036305
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036305
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. [CL:0000059]


systematic_name: M12960
exact_source: GO:0036314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. [GOC:bf]


systematic_name: M14197
exact_source: GO:0036315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus. [GOC:bf]


systematic_name: M34155
exact_source: GO:0036324
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036324
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:uh, PMID:12967471, Wikipedia:Kinase_insert_domain_receptor, Wikipedia:VEGF_receptors]


systematic_name: M45137
exact_source: GO:0036335
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036335
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells. [GOC:nhn, PMID:22042863, PMID:22608824]


systematic_name: M10441
exact_source: GO:0036336
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036336
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a dendritic cell within or between different tissues and organs of the body. [CL:0000451, GOC:nhn, PMID:19339990]


systematic_name: M34156
exact_source: GO:0036337
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036337
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily. [GOC:nhn, PMID:12040174, Wikipedia:Fas_receptor]


systematic_name: M15830
exact_source: GO:0036342
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036342
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. [GOC:bf, GOC:kmv, Wikipedia:Chordate]


systematic_name: M46782
exact_source: GO:0036343
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036343
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument. [GOC:nhn, GOC:pr, PMID:17159989, Wikipedia:Psychomotor_learning]


systematic_name: M12943
exact_source: GO:0036344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. [CL:0000233, GOC:BHF, GOC:vk]


systematic_name: M23444
exact_source: GO:0036376
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036376
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region. [GOC:vw, PMID:14674689]


systematic_name: M42775
exact_source: GO:0036438
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036438
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina. [GOC:nhn, PMID:22095752]


systematic_name: M23446
exact_source: GO:0036444
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036444
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix. [GOC:vw]


systematic_name: M23447
exact_source: GO:0036446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an undifferentiated cell acquires the features of a myofibroblast cell. [CL:0000186, GOC:nhn]


systematic_name: M23448
exact_source: GO:0036462
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036462
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface. [GOC:bf, GOC:PARL, PMID:21785459]


systematic_name: M11777
exact_source: GO:0036465
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036465
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. [GOC:bf, GOC:pad, GOC:PARL, PMID:15217342, PMID:22026965, PMID:23245563]


systematic_name: M46784
exact_source: GO:0036466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate. [GOC:aruk, GOC:bc, GOC:bf, GOC:dos, GOC:pad, GOC:PARL, PMID:15217342]


systematic_name: M23453
exact_source: GO:0036480
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036480
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. [GOC:bf, GOC:PARL, PMID:23858059]


systematic_name: M23454
exact_source: GO:0036481
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036481
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2). [GOC:bf, GOC:PARL]


systematic_name: M23455
exact_source: GO:0036490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242]


systematic_name: M34158
exact_source: GO:0036491
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036491
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress. [GOC:bf, GOC:PARL, PMID:14676213, PMID:16835242]


systematic_name: M34159
exact_source: GO:0036493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress. [GOC:bf, GOC:PARL]


systematic_name: M10426
exact_source: GO:0036498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB. [GOC:bf, GOC:PARL, PMID:22013210]


systematic_name: M42776
exact_source: GO:0036499
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036499
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity. [GOC:bf, GOC:PARL, PMID:22013210, PMID:27629041]


systematic_name: M23457
exact_source: GO:0036500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity. [GOC:bf, GOC:PARL, PMID:22013210]


systematic_name: M15534
exact_source: GO:0036503
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036503
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome. [GOC:bf, GOC:PARL, PMID:20940304, PMID:21969857]


systematic_name: M48435
exact_source: GO:0036514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues. [GOC:bf, GOC:PARL, PMID:21106844, PMID:23517308]


systematic_name: M48436
exact_source: GO:0036515
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0036515
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues. [CL:0000850, GOC:bf, GOC:PARL, PMID:21106844]


systematic_name: M23459
exact_source: GO:0038001
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038001
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other. [GOC:mtg_signaling_feb11, ISBN:3527303782]


systematic_name: M23460
exact_source: GO:0038003
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038003
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by an opioid binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:bf, PMID:20494127]


systematic_name: M23461
exact_source: GO:0038007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance. [GOC:signaling, PMID:10399919, PMID:15960985, PMID:19785719, PMID:20108323]


systematic_name: M23462
exact_source: GO:0038026
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038026
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, PMID:12827279, PMID:20223215]


systematic_name: M23463
exact_source: GO:0038027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by apolipoprotein A-I binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:signaling, PMID:16443932]


systematic_name: M13441
exact_source: GO:0038034
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038034
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor. [GOC:al, GOC:ppm, GOC:pr, PMID:15044679]


systematic_name: M46786
exact_source: GO:0038043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-5 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:signaling]


systematic_name: M48437
exact_source: GO:0038060
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038060
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP. [GOC:signaling, PMID:21549190, PMID:22019632]


systematic_name: M13738
exact_source: GO:0038061
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038061
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette characterized by the NIK-dependent processing and activation of NF-kappaB. Begins with activation of the NF-kappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-kappa B2 protein (p100) leading to p100 processing and release of an active NF-kappaB (p52). The non-canonical NF-kappaB signaling pathway is generally activated by ligands of the TNF receptor superfamily, including lymphotoxin beta (LTB), CD40, OX40, RANK, TWEAK and B cell-activating factor (BAFF). [GOC:bf, GOC:mg2, GOC:signaling, GOC:vs, PMID:11239468, PMID:15140882, PMID:34659217]


systematic_name: M23467
exact_source: GO:0038063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by collagen binding to its receptor on the surface of a target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:uh, PMID:15888913, PMID:16626936]


systematic_name: M23468
exact_source: GO:0038065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:uh, PMID:21568710]


systematic_name: M23469
exact_source: GO:0038066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A MAPK cascade containing at least the p38MAPK (MAPK14) MAP kinase, or Hog1 in yeast. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of p38MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The p38MAPK cascade is activated by stress signals, including hyperosmolarity, as well as by G protein-coupled receptors, growth factors, and cytokines, and results in cellular responses such as cell proliferation, cell differentiation, apoptosis and inflammation. [PMID:20811974, PMID:23125017, PMID:32794416]


systematic_name: M14883
exact_source: GO:0038083
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038083
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein. [PMID:10037737, PMID:10068444, PMID:10940390]


systematic_name: M10406
exact_source: GO:0038084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:signaling, PMID:17470632]


systematic_name: M23471
exact_source: GO:0038092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by nodal protein binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:vk, PMID:17287255]


systematic_name: M13258
exact_source: GO:0038093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. [GOC:phg, Wikipedia:Fc_receptor]


systematic_name: M42777
exact_source: GO:0038094
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038094
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. [GOC:phg, PMID:11244038]


systematic_name: M12670
exact_source: GO:0038095
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038095
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. [GOC:phg, PMID:12413516, PMID:15048725]


systematic_name: M42778
exact_source: GO:0038110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-2 binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling]


systematic_name: M12775
exact_source: GO:0038127
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038127
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:jc, PMID:16460914, Wikipedia:ErbB]


systematic_name: M11834
exact_source: GO:0038128
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038128
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB2 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. [GOC:jc, PMID:16460914, Reactome:R-HSA-1227986]


systematic_name: M45138
exact_source: GO:0038129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission. [GOC:jc, PMID:16460914, Reactome:R-HSA-1247497]


systematic_name: M45139
exact_source: GO:0038130
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038130
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:jc, PMID:16460914, Reactome:R-HSA-1236394]


systematic_name: M45140
exact_source: GO:0038134
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038134
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR. [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589]


systematic_name: M45141
exact_source: GO:0038135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. [GOC:signaling, PMID:16460914, Reactome:R-HSA-1963589]


systematic_name: M45142
exact_source: GO:0038138
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038138
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:signaling, PMID:16460914, Reactome:R-HSA-1250220]


systematic_name: M23474
exact_source: GO:0038145
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038145
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:signaling, GOC:uh, PMID:12138890, Wikipedia:Macrophage_colony-stimulating_factor]


systematic_name: M42779
exact_source: GO:0038146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the chemokine CXCL12 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling, Wikipedia:Stromal_cell-derived_factor-1]


systematic_name: M46787
exact_source: GO:0038154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of interleukin-11 to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling]


systematic_name: M46788
exact_source: GO:0038156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-3 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling]


systematic_name: M48438
exact_source: GO:0038158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R). [GOC:nhn, GOC:signaling]


systematic_name: M45864
exact_source: GO:0038159
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038159
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling]


systematic_name: M48439
exact_source: GO:0038160
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038160
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn]


systematic_name: M29163
exact_source: GO:0038163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by thrombopoietin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:nhn, GOC:signaling, PMID:19630807]


systematic_name: M23477
exact_source: GO:0038166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by angiotensin II binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nhn, GOC:signaling, PMID:10977869]


systematic_name: M23478
exact_source: GO:0038169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:jc, PMID:18006219, PMID:8769369]


systematic_name: M23479
exact_source: GO:0038171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids. [GOC:bf, GOC:jc, GOC:signaling, Wikipedia:Cannabinoid]


systematic_name: M46789
exact_source: GO:0038172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-33 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:jc, GOC:signaling]


systematic_name: M46790
exact_source: GO:0038173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-17A binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:jc, GOC:signaling]


systematic_name: M16665
exact_source: GO:0038179
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038179
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons. [GOC:bf, GOC:jc, GOC:signaling, PMID:17466268, Wikipedia:Neurotrophin]


systematic_name: M23480
exact_source: GO:0038180
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038180
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by nerve growth factor (NGF) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, PMID:11520933]


systematic_name: M40423
exact_source: GO:0038183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by bile acid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:signaling, PMID:12016314]


systematic_name: M23481
exact_source: GO:0038202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. [GOC:lb]


systematic_name: M23482
exact_source: GO:0038203
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0038203
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components. [GOC:lb]


systematic_name: M23484
exact_source: GO:0039529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. [GOC:bf, PMID:17328678, PMID:19620789, PMID:21435580, PMID:25579795]


systematic_name: M23485
exact_source: GO:0039530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. [GOC:bf, PMID:19620789, PMID:33087405]


systematic_name: M15708
exact_source: GO:0039531
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039531
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a cytoplasmic pattern recognition receptor signaling pathway. [GOC:bf, GOC:jl]


systematic_name: M23486
exact_source: GO:0039532
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039532
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the series of a cytoplasmic pattern recognition receptor signaling pathway. [GOC:bf, GOC:jl]


systematic_name: M23487
exact_source: GO:0039533
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039533
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. [GOC:bf, GOC:jl]


systematic_name: M40424
exact_source: GO:0039535
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039535
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the RIG-I signaling pathway. [GOC:bf, GOC:jl]


systematic_name: M23488
exact_source: GO:0039536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the RIG-I signaling pathway. [GOC:bf, GOC:jl]


systematic_name: M42780
exact_source: GO:0039663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell. [GOC:bf, GOC:jl, UniProtKB-KW:KW-1168]


systematic_name: M23489
exact_source: GO:0039692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0039692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II. [GOC:bf, GOC:jl, ISBN:0198506732, VZ:1937]


systematic_name: M15825
exact_source: GO:0040001
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040001
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs. [GOC:ai]


systematic_name: M1108
exact_source: GO:0040007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The increase in size or mass of an entire organism, a part of an organism or a cell. [GOC:bf, GOC:ma]


systematic_name: M1707
exact_source: GO:0040008
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040008
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. [GOC:ems, GOC:mah]


systematic_name: M45143
exact_source: GO:0040012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. [GOC:ems]


systematic_name: M40426
exact_source: GO:0040013
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040013
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. [GOC:go_curators]


systematic_name: M12396
exact_source: GO:0040014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. [GOC:dph, GOC:ems, GOC:tb]


systematic_name: M13946
exact_source: GO:0040015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. [GOC:dph, GOC:ems, GOC:tb]


systematic_name: M40427
exact_source: GO:0040017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. [GOC:go_curators]


systematic_name: M16157
exact_source: GO:0040018
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040018
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M16028
exact_source: GO:0040019
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040019
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of embryonic development. [GOC:go_curators]


systematic_name: M10801
exact_source: GO:0040020
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040020
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. [GOC:ems, GOC:ma]


systematic_name: M16267
exact_source: GO:0040029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal. [PMID:10521337, PMID:11498582, PMID:22243696, PMID:34414474]


systematic_name: M23494
exact_source: GO:0040031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA. [GOC:jl]


systematic_name: M14964
exact_source: GO:0040034
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040034
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. [PMID:9442909]


systematic_name: M13122
exact_source: GO:0040036
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040036
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. [GOC:go_curators]


systematic_name: M12067
exact_source: GO:0040037
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040037
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. [GOC:go_curators]


systematic_name: M45865
exact_source: GO:0040038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0040038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes. [GOC:ems, ISBN:0198506732]


systematic_name: M15562
exact_source: GO:0042026
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042026
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. [GOC:mb]


systematic_name: M16901
exact_source: GO:0042044
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042044
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M45867
exact_source: GO:0042059
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042059
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. [GOC:go_curators]


systematic_name: M12074
exact_source: GO:0042060
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042060
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events that restore integrity to a damaged tissue, following an injury. [GOC:bf, PMID:15269788]


systematic_name: M3208
exact_source: GO:0042063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. [GOC:dgh, GOC:jid]


systematic_name: M15930
exact_source: GO:0042069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. [GOC:go_curators]


systematic_name: M23499
exact_source: GO:0042073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2]


systematic_name: M13468
exact_source: GO:0042074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437]


systematic_name: M12589
exact_source: GO:0042088
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042088
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin. [GOC:add, ISBN:0781735149]


systematic_name: M23501
exact_source: GO:0042092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. [GOC:add, ISBN:0781735149, PMID:18000958, PMID:18007680, PMID:20065995, PMID:20200518]


systematic_name: M14546
exact_source: GO:0042104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the rate or extent of activated T cell proliferation. [GOC:jl]


systematic_name: M2810
exact_source: GO:0042110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M10657
exact_source: GO:0042113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M13410
exact_source: GO:0042116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149, PMID:14506301]


systematic_name: M23505
exact_source: GO:0042117
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042117
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149]


systematic_name: M23506
exact_source: GO:0042118
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042118
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484]


systematic_name: M23509
exact_source: GO:0042138
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042138
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination. [GOC:elh, GOC:jl, PMID:11529427]


systematic_name: M15236
exact_source: GO:0042147
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042147
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport. [GOC:jl, PMID:10873832, PMID:16936697]


systematic_name: M23510
exact_source: GO:0042148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. [GOC:elh, PMID:10357855]


systematic_name: M15497
exact_source: GO:0042149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose. [GOC:jl]


systematic_name: M10659
exact_source: GO:0042157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. [ISBN:0198506732]


systematic_name: M13286
exact_source: GO:0042158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. [ISBN:0198506732]


systematic_name: M23511
exact_source: GO:0042159
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042159
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. [ISBN:0198506732]


systematic_name: M13743
exact_source: GO:0042176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. [GOC:go_curators, GOC:jl]


systematic_name: M11768
exact_source: GO:0042177
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042177
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082]


systematic_name: M23512
exact_source: GO:0042178
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042178
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:jl, GOC:krc]


systematic_name: M11614
exact_source: GO:0042180
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042180
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. [GOC:jl, ISBN:0787650153]


systematic_name: M14421
exact_source: GO:0042181
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042181
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. [GOC:go_curators]


systematic_name: M23513
exact_source: GO:0042182
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042182
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. [GOC:go_curators]


systematic_name: M11001
exact_source: GO:0042219
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042219
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. [GOC:ai]


systematic_name: M10535
exact_source: GO:0042220
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042220
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. [GOC:ef, GOC:jl]


systematic_name: M23517
exact_source: GO:0042249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates. [GOC:ascb_2009, GOC:dph, GOC:jl, GOC:tb]


systematic_name: M10214
exact_source: GO:0042254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis]


systematic_name: M11348
exact_source: GO:0042255
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042255
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. [GOC:ma, PMID:30467428]


systematic_name: M23518
exact_source: GO:0042256
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042256
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional cytosolic ribosome. Distinct stages of this process take place first in the nucleolus, then in the nucleus and finally in the cytosol. [GOC:ma, PMID:30467428]


systematic_name: M34161
exact_source: GO:0042270
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042270
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of protecting a cell from natural killer cell mediated cytotoxicity. [GOC:add, ISBN:0781735149]


systematic_name: M16031
exact_source: GO:0042273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. [GOC:jl]


systematic_name: M12963
exact_source: GO:0042274
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042274
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis. [GOC:jl]


systematic_name: M14864
exact_source: GO:0042276
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042276
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. [GOC:elh, GOC:jl, PMID:11485998]


systematic_name: M23522
exact_source: GO:0042278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:jl, ISBN:0140512713]


systematic_name: M13884
exact_source: GO:0042303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. [GOC:jl, ISBN:0198506732]


systematic_name: M14401
exact_source: GO:0042304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. [GOC:go_curators, GOC:jl]


systematic_name: M45144
exact_source: GO:0042306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. [GOC:jl]


systematic_name: M45145
exact_source: GO:0042307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. [GOC:jl]


systematic_name: M42782
exact_source: GO:0042308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. [GOC:jl]


systematic_name: M40429
exact_source: GO:0042310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure. [GOC:pr, ISBN:0192800752]


systematic_name: M13507
exact_source: GO:0042311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure. [GOC:pr, ISBN:0192800981]


systematic_name: M10561
exact_source: GO:0042325
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042325
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. [GOC:jl]


systematic_name: M15361
exact_source: GO:0042326
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042326
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. [GOC:jl]


systematic_name: M4304
exact_source: GO:0042327
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042327
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. [GOC:jl]


systematic_name: M12201
exact_source: GO:0042330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a motile cell or organism in response to an external stimulus. [GOC:jl, ISBN:0192801023]


systematic_name: M29167
exact_source: GO:0042339
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042339
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. [GOC:go_curators]


systematic_name: M46791
exact_source: GO:0042357
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042357
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle. [GOC:jl, ISBN:0198506732]


systematic_name: M13023
exact_source: GO:0042359
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042359
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). [GOC:mah, ISBN:0471331309]


systematic_name: M45146
exact_source: GO:0042360
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042360
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. [GOC:jl, ISBN:0198506732]


systematic_name: M23525
exact_source: GO:0042362
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042362
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. [GOC:jl, ISBN:0198506732]


systematic_name: M42783
exact_source: GO:0042363
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042363
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. [GOC:jl, ISBN:0198506732]


systematic_name: M23527
exact_source: GO:0042364
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042364
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water. [GOC:jl]


systematic_name: M23528
exact_source: GO:0042368
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042368
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3). [GOC:mah, ISBN:0471331309]


systematic_name: M29168
exact_source: GO:0042373
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042373
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule. [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k]


systematic_name: M17324
exact_source: GO:0042391
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042391
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732]


systematic_name: M6149
exact_source: GO:0042398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. [GOC:ai]


systematic_name: M11344
exact_source: GO:0042403
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042403
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. [GOC:jl, ISBN:0198506732]


systematic_name: M11776
exact_source: GO:0042407
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042407
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The assembly of cristae, the inwards folds of the inner mitochondrial membrane. [GOC:jl, ISBN:0198506732]


systematic_name: M23529
exact_source: GO:0042415
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042415
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. [GOC:jl, ISBN:0198506732]


systematic_name: M23530
exact_source: GO:0042416
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042416
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. [GOC:jl, ISBN:0198506732]


systematic_name: M12513
exact_source: GO:0042417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. [GOC:jl, ISBN:0198506732]


systematic_name: M23532
exact_source: GO:0042421
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042421
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. [GOC:jl, ISBN:0198506732]


systematic_name: M29170
exact_source: GO:0042428
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042428
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. [GOC:jl, ISBN:0198506732]


systematic_name: M13964
exact_source: GO:0042430
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042430
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. [GOC:jl, GOC:mah]


systematic_name: M23534
exact_source: GO:0042435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. [GOC:jl]


systematic_name: M48440
exact_source: GO:0042436
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042436
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. [GOC:jl]


systematic_name: M29171
exact_source: GO:0042439
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042439
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it. [GOC:mah]


systematic_name: M13629
exact_source: GO:0042440
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042440
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin. [GOC:jl, ISBN:0198506732]


systematic_name: M3753
exact_source: GO:0042445
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042445
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. [GOC:jl]


systematic_name: M13291
exact_source: GO:0042446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. [GOC:jl]


systematic_name: M23537
exact_source: GO:0042447
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042447
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. [GOC:jl]


systematic_name: M16793
exact_source: GO:0042448
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042448
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. [GOC:jl, http://www.cogsci.princeton.edu/]


systematic_name: M13727
exact_source: GO:0042451
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042451
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:go_curators]


systematic_name: M16271
exact_source: GO:0042454
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042454
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. [GOC:jl]


systematic_name: M13417
exact_source: GO:0042461
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042461
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. [GOC:go_curators]


systematic_name: M15705
exact_source: GO:0042462
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042462
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. [GOC:jl, ISBN:0192800981]


systematic_name: M14023
exact_source: GO:0042471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. [GOC:jl, ISBN:0192801023]


systematic_name: M16847
exact_source: GO:0042472
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042472
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. [GOC:jl, ISBN:0192801023]


systematic_name: M23538
exact_source: GO:0042473
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042473
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. [GOC:jl, ISBN:0192801023]


systematic_name: M13066
exact_source: GO:0042474
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042474
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). [GOC:jl, ISBN:0192801023]


systematic_name: M15056
exact_source: GO:0042475
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042475
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. [GOC:cjm, GOC:mah, GOC:mtg_sensu, PMID:10333884, PMID:15355794]


systematic_name: M16906
exact_source: GO:0042476
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0042476
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. [GOC:jl, GOC:mah]


