# gene_set_details

systematic_name: M24343
exact_source: GO:0070104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of an interleukin-6-mediated signaling pathway. [GOC:BHF, GOC:mah]


systematic_name: M24344
exact_source: GO:0070106
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070106
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-27 binding to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:add, GOC:BHF, GOC:mah, GOC:signaling]


systematic_name: M24345
exact_source: GO:0070120
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070120
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:mah]


systematic_name: M42900
exact_source: GO:0070125
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070125
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. [GOC:mah]


systematic_name: M24347
exact_source: GO:0070127
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070127
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion. [GOC:mah]


systematic_name: M45193
exact_source: GO:0070129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. [GOC:mah]


systematic_name: M24348
exact_source: GO:0070131
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070131
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. [GOC:mah]


systematic_name: M24349
exact_source: GO:0070141
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070141
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. [GOC:BHF, GOC:mah]


systematic_name: M29266
exact_source: GO:0070163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell. [GOC:mah]


systematic_name: M12360
exact_source: GO:0070166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel. [GOC:BHF, GOC:mah, GOC:sl, PMID:10206335, PMID:16931858, PMID:21196346]


systematic_name: M45907
exact_source: GO:0070167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. [GOC:mah]


systematic_name: M45908
exact_source: GO:0070168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. [GOC:mah]


systematic_name: M45909
exact_source: GO:0070169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. [GOC:mah]


systematic_name: M24352
exact_source: GO:0070170
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070170
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. [GOC:BHF, GOC:mah]


systematic_name: M24353
exact_source: GO:0070172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. [GOC:BHF, GOC:mah]


systematic_name: M24354
exact_source: GO:0070173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. [GOC:BHF, GOC:mah]


systematic_name: M42901
exact_source: GO:0070175
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070175
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel. [GOC:BHF, GOC:mah]


systematic_name: M24355
exact_source: GO:0070189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine. [CHEBI:28683, GOC:mah, GOC:rph]


systematic_name: M12195
exact_source: GO:0070193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis. [GOC:mah]


systematic_name: M46835
exact_source: GO:0070197
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070197
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation. [GOC:jp, GOC:pr, GOC:vw, PMID:18818742]


systematic_name: M12907
exact_source: GO:0070198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome. [GOC:BHF, GOC:mah]


systematic_name: M24357
exact_source: GO:0070200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein to a specific location in the telomeric region of a chromosome. [GOC:BHF, GOC:mah]


systematic_name: M42902
exact_source: GO:0070201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. [GOC:BHF, GOC:mah]


systematic_name: M11451
exact_source: GO:0070202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. [GOC:BHF, GOC:mah]


systematic_name: M12509
exact_source: GO:0070206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits. [GOC:hjd]


systematic_name: M24359
exact_source: GO:0070212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain. [GOC:BHF, GOC:mah, GOC:rl, PMID:25043379]


systematic_name: M24360
exact_source: GO:0070213
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070213
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. [GOC:BHF, GOC:rl]


systematic_name: M16177
exact_source: GO:0070227
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070227
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M11217
exact_source: GO:0070228
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070228
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M13947
exact_source: GO:0070229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M10232
exact_source: GO:0070230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M16401
exact_source: GO:0070231
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070231
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M12536
exact_source: GO:0070232
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070232
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the occurrence or rate of T cell death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M13278
exact_source: GO:0070233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M15584
exact_source: GO:0070234
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070234
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M24362
exact_source: GO:0070242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a thymocyte, an immature T cell located in the thymus. [CL:0000893, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M12760
exact_source: GO:0070243
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070243
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the occurrence or rate of thymocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M24363
exact_source: GO:0070244
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070244
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196]


systematic_name: M14073
exact_source: GO:0070252
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070252
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. [GOC:mah]


systematic_name: M24365
exact_source: GO:0070254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. [GOC:add, ISBN:068340007X, ISBN:0721662544]


systematic_name: M24366
exact_source: GO:0070255
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070255
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. [GOC:add]


systematic_name: M42903
exact_source: GO:0070257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. [GOC:add]


systematic_name: M24368
exact_source: GO:0070262
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070262
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine. [GOC:bf]


systematic_name: M46836
exact_source: GO:0070266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former. [GOC:BHF, GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, PMID:18846107, PMID:20823910, PMID:21737330, PMID:21760595, PMID:21876153]


systematic_name: M24369
exact_source: GO:0070268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). [GOC:krc, PMID:18846107]


systematic_name: M24370
exact_source: GO:0070269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. [GOC:mtg_apoptosis, PMID:18846107, PMID:21760595]


systematic_name: M24371
exact_source: GO:0070278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. [GOC:mah]


systematic_name: M12301
exact_source: GO:0070286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion. [GOC:cilia, GOC:mah, PMID:19052621]


systematic_name: M34228
exact_source: GO:0070291
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070291
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group. [CHEBI:52640, GOC:elh, PMID:14634025, PMID:15878693]


systematic_name: M29267
exact_source: GO:0070292
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070292
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group. [GOC:elh, GOC:mah, PMID:14634025, PMID:15878693]


systematic_name: M15554
exact_source: GO:0070293
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070293
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). [GOC:dph, GOC:mah, GOC:yaf]


systematic_name: M40490
exact_source: GO:0070294
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070294
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. [GOC:dph, GOC:mah]


systematic_name: M45194
exact_source: GO:0070295
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070295
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. [GOC:dph, GOC:mah]


systematic_name: M14090
exact_source: GO:0070296
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070296
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum. [GOC:BHF, GOC:vk]


systematic_name: M12852
exact_source: GO:0070301
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070301
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. [CHEBI:16240, GOC:mah]


systematic_name: M10591
exact_source: GO:0070302
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070302
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade. [GOC:mah]


systematic_name: M14839
exact_source: GO:0070303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. [GOC:mah]


systematic_name: M11724
exact_source: GO:0070304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade. [GOC:mah]


systematic_name: M24372
exact_source: GO:0070305
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070305
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. [GOC:sl]


systematic_name: M10247
exact_source: GO:0070306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. [GOC:mah, PMID:7693735]


systematic_name: M16678
exact_source: GO:0070307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. [GOC:mah, PMID:7693735]


systematic_name: M24373
exact_source: GO:0070309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. [GOC:mah, PMID:7693735]


systematic_name: M24374
exact_source: GO:0070314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence. [GOC:mah, GOC:mtg_cell_cycle, ISBN:0815316194]


systematic_name: M42904
exact_source: GO:0070315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation. [GOC:mah, ISBN:0815316194]


systematic_name: M42906
exact_source: GO:0070317
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070317
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase. [GOC:mah]


systematic_name: M42907
exact_source: GO:0070318
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070318
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase. [GOC:mah]


systematic_name: M24375
exact_source: GO:0070327
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070327
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:rph]


systematic_name: M24376
exact_source: GO:0070341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. [GOC:mah, GOC:sl]


systematic_name: M42908
exact_source: GO:0070344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of fat cell proliferation. [GOC:mah, GOC:sl]


systematic_name: M24378
exact_source: GO:0070358
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070358
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell. [GOC:mah, PMID:15773977]


systematic_name: M24379
exact_source: GO:0070365
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070365
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. [CL:0000182, PMID:7588884]


systematic_name: M16677
exact_source: GO:0070371
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070371
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A MAPK cascade containing at least the ERK1 or ERK2 MAP kinases. It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK1 or ERK2. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier. The ERK1/ERK2 cascade is activated by mitogens, growth factors, G protein-coupled receptors, and results in cellular responses such as cell proliferation, cell differentiation and development. [PMID:20811974, PMID:23125017, PMID:28903453]


systematic_name: M10186
exact_source: GO:0070373
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070373
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. [GOC:add, ISBN:0121245462, ISBN:0896039986]


systematic_name: M15144
exact_source: GO:0070374
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070374
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. [GOC:mah]


systematic_name: M45195
exact_source: GO:0070375
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070375
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiation and development. [PMID:16376520, PMID:16880823, PMID:20811974, PMID:23125017, PMID:28903453]


systematic_name: M24381
exact_source: GO:0070391
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070391
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor. [GOC:add, PMID:14665680, PMID:16020688]


systematic_name: M24382
exact_source: GO:0070417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. [GOC:jp]


systematic_name: M24383
exact_source: GO:0070424
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070424
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway. [GOC:add]


systematic_name: M40491
exact_source: GO:0070426
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070426
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway. [GOC:add]


systematic_name: M29268
exact_source: GO:0070427
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070427
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 1 (NOD1) protein receptor, and ending with regulation of a downstream cellular process. [GOC:add, PMID:17944960, PMID:18585455]


systematic_name: M24384
exact_source: GO:0070431
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070431
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process. [GOC:add, PMID:17944960, PMID:18585455]


systematic_name: M24385
exact_source: GO:0070432
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070432
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway. [GOC:add]


systematic_name: M24386
exact_source: GO:0070444
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070444
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. [GOC:mah, GOC:sl, PMID:15504915]


systematic_name: M24387
exact_source: GO:0070459
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070459
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. [GOC:mah, ISBN:0198506732]


systematic_name: M24388
exact_source: GO:0070471
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070471
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth. [GOC:sl]


systematic_name: M24389
exact_source: GO:0070474
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070474
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of uterine smooth muscle contraction. [GOC:go_curators]


systematic_name: M24390
exact_source: GO:0070475
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070475
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule. [GOC:mah]


systematic_name: M12903
exact_source: GO:0070482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. [GOC:BHF, GOC:mah]


systematic_name: M24391
exact_source: GO:0070486
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070486
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules. [GOC:sl, PMID:12972508]


systematic_name: M24392
exact_source: GO:0070487
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070487
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The adhesion of one monocyte to one or more other monocytes via adhesion molecules. [GOC:sl, PMID:12972508]


systematic_name: M24393
exact_source: GO:0070493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:mah, PMID:1672265]


systematic_name: M14173
exact_source: GO:0070498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-1 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:mah, GOC:signaling]


systematic_name: M34229
exact_source: GO:0070507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. [GOC:mah]


systematic_name: M15215
exact_source: GO:0070525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules. [GOC:imk, GOC:mah, PMID:19287007]


systematic_name: M16560
exact_source: GO:0070527
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070527
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:BHF, GOC:vk]


systematic_name: M13141
exact_source: GO:0070528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:BHF, GOC:mah]


systematic_name: M15079
exact_source: GO:0070534
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070534
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair. [GOC:mah, PMID:15556404]


systematic_name: M15375
exact_source: GO:0070536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. [GOC:mah, PMID:19202061, PMID:19214193]


systematic_name: M14177
exact_source: GO:0070542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. [GOC:lp]


systematic_name: M13436
exact_source: GO:0070555
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070555
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. [GOC:BHF, GOC:mah]


systematic_name: M24396
exact_source: GO:0070561
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070561
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands. [GOC:BHF, GOC:mah, PMID:12637589]


systematic_name: M24397
exact_source: GO:0070562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity. [GOC:BHF, GOC:mah]


systematic_name: M42909
exact_source: GO:0070564
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070564
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity. [GOC:BHF, GOC:mah]


systematic_name: M14165
exact_source: GO:0070570
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070570
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. [GOC:mah]


systematic_name: M24398
exact_source: GO:0070571
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070571
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. [GOC:mah]


systematic_name: M24399
exact_source: GO:0070572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage. [GOC:mah]


systematic_name: M34230
exact_source: GO:0070574
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070574
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M15269
exact_source: GO:0070585
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070585
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within the mitochondrion. [GOC:ecd]


systematic_name: M15680
exact_source: GO:0070588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M24401
exact_source: GO:0070593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which dendrites recognize and avoid contact with sister dendrites from the same cell. [GOC:sart, PMID:17482551]


systematic_name: M24402
exact_source: GO:0070601
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070601
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome. [GOC:mah]


systematic_name: M46837
exact_source: GO:0070602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome. [GOC:mah]


systematic_name: M13303
exact_source: GO:0070633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a substance from one side of an epithelium to the other. [GOC:mah, GOC:yaf, ISBN:0716731363]


systematic_name: M24403
exact_source: GO:0070640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol. [GOC:BHF, GOC:mah]


systematic_name: M11656
exact_source: GO:0070646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein. [GOC:mah]


systematic_name: M10218
exact_source: GO:0070663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of leukocyte proliferation. [GOC:add, GOC:mah]


systematic_name: M10715
exact_source: GO:0070664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. [GOC:add, GOC:mah]


systematic_name: M11973
exact_source: GO:0070665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. [GOC:add, GOC:mah]


systematic_name: M24404
exact_source: GO:0070669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus. [GOC:mah]


systematic_name: M10629
exact_source: GO:0070670
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070670
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus. [GOC:mah]


systematic_name: M24405
exact_source: GO:0070671
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070671
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus. [GOC:mah]


systematic_name: M24406
exact_source: GO:0070672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus. [GOC:mah]


systematic_name: M24407
exact_source: GO:0070673
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070673
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus. [GOC:mah]


systematic_name: M46838
exact_source: GO:0070729
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070729
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell. [GOC:mah, ISBN:0198506732]


systematic_name: M14320
exact_source: GO:0070741
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070741
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus. [GOC:mah]


systematic_name: M48493
exact_source: GO:0070777
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070777
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid  is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore. [GOC:mah, GOC:rph]


systematic_name: M24410
exact_source: GO:0070778
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070778
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-aspartate across a membrane by means of some agent such as a transporter or a pore. [PMID:21307582]


systematic_name: M24411
exact_source: GO:0070782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity. [GOC:mah, GOC:mtg_apoptosis, GOC:rk, PMID:11536005]


systematic_name: M15752
exact_source: GO:0070828
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070828
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. [GOC:mah]


systematic_name: M24413
exact_source: GO:0070831
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070831
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. [GOC:mah]


systematic_name: M42912
exact_source: GO:0070836
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070836
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. [GOC:BHF, GOC:mah, GOC:vk, PMID:12633858]


systematic_name: M29270
exact_source: GO:0070837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C. [GOC:sl]


systematic_name: M24414
exact_source: GO:0070841
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070841
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:BHF, GOC:mah]


systematic_name: M24415
exact_source: GO:0070842
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070842
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein. [GOC:BHF, GOC:rl, PMID:14675537]


systematic_name: M14540
exact_source: GO:0070848
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070848
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:BHF, GOC:mah]


systematic_name: M11712
exact_source: GO:0070849
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070849
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. [GOC:BHF, GOC:mah]


systematic_name: M24416
exact_source: GO:0070857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. [GOC:BHF, GOC:mah]


systematic_name: M15603
exact_source: GO:0070861
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070861
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. [GOC:mah]


systematic_name: M24417
exact_source: GO:0070862
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070862
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum. [GOC:mah]


systematic_name: M24418
exact_source: GO:0070863
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070863
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum. [GOC:mah]


systematic_name: M13753
exact_source: GO:0070873
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070873
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. [GOC:mah]


systematic_name: M24419
exact_source: GO:0070874
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070874
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. [GOC:mah]


systematic_name: M12515
exact_source: GO:0070875
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070875
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. [GOC:mah]


systematic_name: M24420
exact_source: GO:0070897
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070897
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotides. [GOC:txnOH]


systematic_name: M24423
exact_source: GO:0070914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). [GOC:mah, PMID:9619100]


systematic_name: M45198
exact_source: GO:0070918
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070918
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process leading to the generation of a functional regulatory non-coding RNA. [GOC:mah, PMID:15196465, PMID:19239886]


systematic_name: M24425
exact_source: GO:0070920
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070920
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing. [GOC:mah]


systematic_name: M24426
exact_source: GO:0070922
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070922
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA. [PMID:14512631, PMID:14744438, PMID:19239886, PMID:22233755, PMID:27184117]


systematic_name: M13708
exact_source: GO:0070925
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070925
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. [GOC:mah]


systematic_name: M24428
exact_source: GO:0070934
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070934
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD). [GOC:mah, PMID:19029303]


systematic_name: M11060
exact_source: GO:0070935
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070935
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA. [GOC:mah, PMID:19029303]


systematic_name: M15645
exact_source: GO:0070936
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070936
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. [GOC:cvs, PMID:15556404]


systematic_name: M24431
exact_source: GO:0070943
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070943
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. [GOC:add, ISBN:0781765196]


systematic_name: M24433
exact_source: GO:0070948
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070948
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil. [GOC:add, GOC:mah]


systematic_name: M12040
exact_source: GO:0070972
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070972
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum. [GOC:mah]


systematic_name: M24435
exact_source: GO:0070973
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070973
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site. [GOC:mah]


systematic_name: M16580
exact_source: GO:0070977
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070977
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. [GOC:dph, GOC:mah]


systematic_name: M12685
exact_source: GO:0070979
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070979
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains. [GOC:jsg, GOC:pr, GOC:sp, PMID:18485873, PMID:20655260, PMID:21113135]


systematic_name: M12935
exact_source: GO:0070986
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070986
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes). [GOC:dph, GOC:gvg, GOC:mah]


systematic_name: M12348
exact_source: GO:0070987
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070987
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. [GOC:elh]


systematic_name: M11148
exact_source: GO:0070989
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070989
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate. [GOC:BHF, GOC:mah, GOC:rl]


systematic_name: M40494
exact_source: GO:0070995
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0070995
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP. [GOC:BHF, GOC:mah]


systematic_name: M12433
exact_source: GO:0071025
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071025
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that identifies and degrades defective or aberrant RNAs. [GOC:dgf, GOC:krc, PMID:18644474]


systematic_name: M46839
exact_source: GO:0071027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that identifies and degrades defective or aberrant RNAs within the nucleus. [GOC:dgf, GOC:krc, PMID:18644474]


systematic_name: M45199
exact_source: GO:0071028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that identifies and degrades defective or aberrant mRNAs within the nucleus. [GOC:dgf, GOC:krc, PMID:11586364, PMID:12417728, PMID:14718167, PMID:18644474]


systematic_name: M48494
exact_source: GO:0071043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome. [GOC:dgf, GOC:krc, PMID:15935759, PMID:16973436]


systematic_name: M14800
exact_source: GO:0071044
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071044
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA). [GOC:dgf, GOC:krc, PMID:17179095, PMID:17855393]


systematic_name: M24439
exact_source: GO:0071051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA. [GOC:dgf, GOC:krc, PMID:18951092]


systematic_name: M14751
exact_source: GO:0071071
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071071
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. [GOC:mah]


systematic_name: M48495
exact_source: GO:0071072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. [GOC:mah]


systematic_name: M24441
exact_source: GO:0071073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids. [GOC:mah]


systematic_name: M34235
exact_source: GO:0071076
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071076
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule. [GOC:vw, PMID:19430462]


systematic_name: M12191
exact_source: GO:0071103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. [GOC:mah]


systematic_name: M46840
exact_source: GO:0071104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus. [GOC:mah, GOC:yaf]


systematic_name: M14737
exact_source: GO:0071107
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071107
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. [GOC:mah, GOC:yaf]


systematic_name: M14122
exact_source: GO:0071108
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071108
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein. [GOC:mah]


systematic_name: M42913
exact_source: GO:0071139
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071139
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged. [GOC:elh, GOC:mah, GOC:vw]


systematic_name: M42914
exact_source: GO:0071166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. [GOC:mah]


systematic_name: M12871
exact_source: GO:0071168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. [GOC:mah]


systematic_name: M24443
exact_source: GO:0071169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein to a part of a chromosome that is organized into chromatin. [GOC:mah]


systematic_name: M46841
exact_source: GO:0071211
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071211
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm. [GOC:mah]


systematic_name: M16709
exact_source: GO:0071214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. [GOC:mah]


systematic_name: M10812
exact_source: GO:0071216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. [GOC:mah]


systematic_name: M48496
exact_source: GO:0071219
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071219
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin. [GOC:mah]


systematic_name: M24445
exact_source: GO:0071224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule. [GOC:mah]


systematic_name: M24446
exact_source: GO:0071225
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071225
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan. [GOC:mah]


systematic_name: M11553
exact_source: GO:0071229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. [GOC:go_curators, GOC:mah, Wikipedia:Acid]


systematic_name: M24447
exact_source: GO:0071233
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071233
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus. [GOC:mah]


systematic_name: M14334
exact_source: GO:0071236
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071236
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. [GOC:mah]


systematic_name: M14161
exact_source: GO:0071241
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071241
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. [GOC:mah]


systematic_name: M40495
exact_source: GO:0071242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. [GO_REF:0000071, GOC:TermGenie, PMID:23509267]


systematic_name: M13181
exact_source: GO:0071243
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071243
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides. [GOC:mah]


systematic_name: M12134
exact_source: GO:0071257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. [GOC:mah]


systematic_name: M10980
exact_source: GO:0071276
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071276
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. [GOC:mah]


systematic_name: M14517
exact_source: GO:0071277
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071277
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. [GOC:mah]


systematic_name: M24449
exact_source: GO:0071280
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071280
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus. [GOC:mah]


systematic_name: M24450
exact_source: GO:0071281
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071281
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. [GOC:mah]


systematic_name: M46842
exact_source: GO:0071284
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071284
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. [GOC:mah]


systematic_name: M24452
exact_source: GO:0071286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus. [GOC:mah]


systematic_name: M24453
exact_source: GO:0071287
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071287
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. [GOC:mah]


systematic_name: M14069
exact_source: GO:0071294
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071294
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. [GOC:mah]


systematic_name: M15636
exact_source: GO:0071295
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071295
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. [GOC:mah]


systematic_name: M12477
exact_source: GO:0071300
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071300
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus. [GOC:mah]


systematic_name: M15639
exact_source: GO:0071305
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071305
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus. [GOC:mah]


systematic_name: M48497
exact_source: GO:0071310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. [GOC:mah]


systematic_name: M16868
exact_source: GO:0071312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. [GOC:mah]


systematic_name: M24454
exact_source: GO:0071313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them. [GOC:mah]


systematic_name: M42915
exact_source: GO:0071314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant. [GOC:mah]


systematic_name: M24456
exact_source: GO:0071316
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071316
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. [GOC:mah]


systematic_name: M12102
exact_source: GO:0071318
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071318
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. [GOC:mah]


systematic_name: M13154
exact_source: GO:0071320
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071320
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus. [GOC:mah]


systematic_name: M45911
exact_source: GO:0071321
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071321
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus. [GOC:mah]


systematic_name: M11029
exact_source: GO:0071322
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071322
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. [GOC:mah]


systematic_name: M48498
exact_source: GO:0071332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. [GOC:mah]


systematic_name: M24458
exact_source: GO:0071340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals. [GOC:bf, GOC:dsf, PMID:19285469]


systematic_name: M42916
exact_source: GO:0071346
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071346
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. [GOC:mah]


systematic_name: M42917
exact_source: GO:0071347
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071347
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus. [GOC:mah]


systematic_name: M14408
exact_source: GO:0071359
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071359
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus. [GOC:mah]


systematic_name: M14247
exact_source: GO:0071360
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071360
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus. [GOC:mah]


systematic_name: M13732
exact_source: GO:0071361
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071361
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. [GOC:mah]


systematic_name: M24459
exact_source: GO:0071362
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071362
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. [GOC:mah]


systematic_name: M16827
exact_source: GO:0071371
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071371
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus. [GOC:mah]


systematic_name: M24460
exact_source: GO:0071372
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071372
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus. [GOC:mah]


systematic_name: M45912
exact_source: GO:0071373
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071373
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus. [GOC:mah]


systematic_name: M24461
exact_source: GO:0071374
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071374
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus. [GOC:mah]


systematic_name: M24462
exact_source: GO:0071375
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071375
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. [GOC:mah]


systematic_name: M12974
exact_source: GO:0071377
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071377
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. [GOC:mah]


systematic_name: M46843
exact_source: GO:0071378
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071378
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth. [GOC:mah]


systematic_name: M10971
exact_source: GO:0071379
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071379
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus. [GOC:mah]


systematic_name: M13725
exact_source: GO:0071380
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071380
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus. [GOC:mah]


systematic_name: M14380
exact_source: GO:0071383
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071383
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. [GOC:mah]


systematic_name: M12623
exact_source: GO:0071384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. [GOC:mah]


systematic_name: M45913
exact_source: GO:0071385
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071385
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. [GOC:mah]


systematic_name: M24463
exact_source: GO:0071389
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071389
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. [GOC:mah]


systematic_name: M14988
exact_source: GO:0071391
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071391
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics. [GOC:mah]


systematic_name: M15287
exact_source: GO:0071392
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071392
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. [GOC:mah]


systematic_name: M42918
exact_source: GO:0071393
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071393
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. [GOC:mah]


systematic_name: M24464
exact_source: GO:0071394
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071394
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. [GOC:mah]


systematic_name: M10653
exact_source: GO:0071396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. [GOC:mah]


systematic_name: M13781
exact_source: GO:0071397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus. [GOC:mah]


systematic_name: M14343
exact_source: GO:0071398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus. [GOC:mah]


systematic_name: M10052
exact_source: GO:0071402
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071402
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. [GOC:mah]


systematic_name: M10841
exact_source: GO:0071407
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071407
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. [GOC:mah]


systematic_name: M24466
exact_source: GO:0071415
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071415
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus. [GOC:mah]


systematic_name: M24467
exact_source: GO:0071420
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071420
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. [GOC:mah]


systematic_name: M13085
exact_source: GO:0071425
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071425
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl]


systematic_name: M24470
exact_source: GO:0071447
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071447
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH. [GOC:mah]


systematic_name: M15152
exact_source: GO:0071450
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071450
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion. [GOC:mah]


systematic_name: M12594
exact_source: GO:0071453
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071453
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. [GOC:mah]


systematic_name: M24471
exact_source: GO:0071455
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071455
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension. [GOC:mah]


systematic_name: M12643
exact_source: GO:0071459
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071459
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome. [GOC:mah]


systematic_name: M40496
exact_source: GO:0071462
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071462
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. [GOC:mah]


systematic_name: M42919
exact_source: GO:0071466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:krc, GOC:mah]


systematic_name: M14462
exact_source: GO:0071467
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071467
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. [GOC:mah, Wikipedia:PH]


systematic_name: M24473
exact_source: GO:0071468
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071468
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. [GOC:go_curators, GOC:mah, Wikipedia:PH]


systematic_name: M15515
exact_source: GO:0071470
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071470
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. [GOC:mah]


systematic_name: M24474
exact_source: GO:0071472
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071472
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. [GOC:mah]


systematic_name: M24475
exact_source: GO:0071474
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071474
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. [GOC:mah]


systematic_name: M24476
exact_source: GO:0071476
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071476
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. [GOC:mah]


systematic_name: M14657
exact_source: GO:0071478
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071478
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. [GOC:mah]


systematic_name: M14071
exact_source: GO:0071479
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071479
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. [GOC:mah]


systematic_name: M11307
exact_source: GO:0071480
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071480
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. [GOC:mah]


systematic_name: M24477
exact_source: GO:0071481
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071481
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). [GOC:mah]


systematic_name: M10846
exact_source: GO:0071482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. [GOC:mah]


systematic_name: M40497
exact_source: GO:0071492
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071492
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. [GOC:mah]


systematic_name: M24478
exact_source: GO:0071493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. [GOC:mah]


systematic_name: M24479
exact_source: GO:0071494
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071494
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. [GOC:mah]


systematic_name: M10729
exact_source: GO:0071496
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071496
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. [GOC:mah]


systematic_name: M10935
exact_source: GO:0071498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface. [GOC:mah]


systematic_name: M24480
exact_source: GO:0071499
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071499
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. [GOC:mah]


systematic_name: M24481
exact_source: GO:0071500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. [GOC:mah]


systematic_name: M29272
exact_source: GO:0071501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:mah]


systematic_name: M42922
exact_source: GO:0071502
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071502
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. [GOC:mah]


systematic_name: M24483
exact_source: GO:0071503
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071503
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus. [GOC:mah, GOC:yaf]


systematic_name: M13829
exact_source: GO:0071514
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071514
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment of epigenetic modifications (imprints) during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation. [PMID:24492710, PMID:31896690, PMID:31965998]


systematic_name: M15378
exact_source: GO:0071526
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071526
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand. [GOC:BHF, GOC:mah, GOC:vk, PMID:15239959]


systematic_name: M48499
exact_source: GO:0071529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum. [GOC:sl, PMID:17043865]


systematic_name: M15307
exact_source: GO:0071542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. [GOC:rph]


systematic_name: M34240
exact_source: GO:0071543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached. [GOC:mah, PMID:12387729]


systematic_name: M15159
exact_source: GO:0071548
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071548
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. [GOC:mah, GOC:yaf]


systematic_name: M16203
exact_source: GO:0071549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus. [GOC:mah, GOC:yaf]


systematic_name: M12916
exact_source: GO:0071559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus. [GOC:mah]


systematic_name: M24489
exact_source: GO:0071578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol. [GOC:vw, PMID:18637840]


systematic_name: M10898
exact_source: GO:0071599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. [GOC:mah]


systematic_name: M42923
exact_source: GO:0071600
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071600
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. [GOC:mah]


systematic_name: M24491
exact_source: GO:0071604
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071604
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3. [GOC:add, GOC:rv, PMID:16891311, PMID:2022183]


systematic_name: M24492
exact_source: GO:0071605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, GOC:rv]


systematic_name: M24493
exact_source: GO:0071608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, GOC:rv]


systematic_name: M24494
exact_source: GO:0071609
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071609
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, GOC:rv]


systematic_name: M24495
exact_source: GO:0071611
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071611
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, GOC:rv]


systematic_name: M45201
exact_source: GO:0071612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, GOC:rv]


systematic_name: M13549
exact_source: GO:0071622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. [GOC:mah]


systematic_name: M42924
exact_source: GO:0071623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. [GOC:mah]


systematic_name: M24496
exact_source: GO:0071624
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071624
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. [GOC:mah]


systematic_name: M13775
exact_source: GO:0071625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The behavior in which an organism produces sounds by a mechanism involving its respiratory system. [GOC:mah]


systematic_name: M24497
exact_source: GO:0071635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta. [GOC:mah]


systematic_name: M14267
exact_source: GO:0071636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta. [GOC:mah]


systematic_name: M24498
exact_source: GO:0071638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1. [GOC:mah]


systematic_name: M24499
exact_source: GO:0071639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1. [GOC:mah]


systematic_name: M42925
exact_source: GO:0071650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. [GOC:mah]


systematic_name: M24500
exact_source: GO:0071651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5. [GOC:mah]


systematic_name: M24502
exact_source: GO:0071671
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071671
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. [GOC:mah]


systematic_name: M24504
exact_source: GO:0071674
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071674
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a mononuclear cell within or between different tissues and organs of the body. [GOC:mah]


systematic_name: M12011
exact_source: GO:0071675
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071675
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. [GOC:mah]


systematic_name: M24505
exact_source: GO:0071676
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071676
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. [GOC:mah]


systematic_name: M24506
exact_source: GO:0071677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. [GOC:mah]


systematic_name: M24507
exact_source: GO:0071679
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071679
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues. [GOC:BHF, GOC:mah]


systematic_name: M24508
exact_source: GO:0071680
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071680
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. [GOC:mah, GOC:yaf]


systematic_name: M42926
exact_source: GO:0071681
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071681
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus. [GOC:mah, GOC:yaf]


systematic_name: M24509
exact_source: GO:0071684
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071684
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case. [GOC:mah]


systematic_name: M42927
exact_source: GO:0071692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. [GOC:mah]


systematic_name: M29274
exact_source: GO:0071694
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071694
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere. [GOC:mah]


systematic_name: M12218
exact_source: GO:0071695
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071695
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. [GOC:mah]


systematic_name: M42928
exact_source: GO:0071696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. [GOC:mah]


systematic_name: M48500
exact_source: GO:0071705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M24512
exact_source: GO:0071706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add]


systematic_name: M16086
exact_source: GO:0071711
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071711
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. [GOC:mah]


systematic_name: M40498
exact_source: GO:0071715
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071715
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds. [GOC:mah]


systematic_name: M40499
exact_source: GO:0071716
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071716
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. [GOC:mah]


systematic_name: M29275
exact_source: GO:0071724
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071724
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus. [GOC:add, PMID:12077222, PMID:12524386, PMID:2757794]


systematic_name: M16967
exact_source: GO:0071731
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071731
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus. [GOC:mah, GOC:yaf]


systematic_name: M24514
exact_source: GO:0071763
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071763
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. [GOC:mah]


systematic_name: M14241
exact_source: GO:0071772
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071772
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus. [GOC:mah, GOC:yaf]


systematic_name: M13039
exact_source: GO:0071774
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071774
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus. [GOC:mah]


systematic_name: M24515
exact_source: GO:0071786
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071786
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section. [GOC:vw, PMID:16469703, PMID:20434336]


systematic_name: M45914
exact_source: GO:0071787
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071787
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section. [GOC:mah, GOC:vw, PMID:16469703, PMID:20434336]


systematic_name: M46844
exact_source: GO:0071798
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071798
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus. [GOC:sl]


systematic_name: M24517
exact_source: GO:0071800
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071800
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell. [GOC:mah, GOC:sl]


systematic_name: M34242
exact_source: GO:0071816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region. [GOC:mah, GOC:sp, PMID:20516149, PMID:20676083]


systematic_name: M15278
exact_source: GO:0071824
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071824
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex. [GOC:mah]


systematic_name: M13277
exact_source: GO:0071825
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071825
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex. [GOC:mah]


systematic_name: M13539
exact_source: GO:0071826
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071826
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. [GOC:mah]


systematic_name: M24519
exact_source: GO:0071830
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071830
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded. [GOC:BHF]


systematic_name: M24520
exact_source: GO:0071838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow. [GOC:mah, GOC:yaf, PMID:17063141]


systematic_name: M46845
exact_source: GO:0071863
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071863
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow. [GOC:mah, GOC:yaf, PMID:17063141]


systematic_name: M24522
exact_source: GO:0071864
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071864
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow. [GOC:mah, GOC:yaf, PMID:17063141]


systematic_name: M42931
exact_source: GO:0071865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow. [GOC:mah, GOC:mtg_apoptosis, GOC:yaf, PMID:17063141]


systematic_name: M24524
exact_source: GO:0071869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. [GOC:BHF, GOC:mah]


systematic_name: M15290
exact_source: GO:0071871
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071871
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. [GOC:BHF, GOC:mah]


systematic_name: M13395
exact_source: GO:0071872
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071872
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system. [GOC:BHF, GOC:mah]


systematic_name: M13056
exact_source: GO:0071875
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071875
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:BHF]


systematic_name: M24525
exact_source: GO:0071878
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071878
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands. [GOC:BHF, GOC:mah]


systematic_name: M40500
exact_source: GO:0071880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by a ligand binding to an adrenergic receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process. [GOC:BHF, GOC:mah, GOC:signaling]


systematic_name: M13996
exact_source: GO:0071887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis]


systematic_name: M24527
exact_source: GO:0071888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. [CL:0000235, GOC:BHF, GOC:mah, GOC:mtg_apoptosis]


systematic_name: M24528
exact_source: GO:0071895
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071895
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. [GOC:sl, PMID:20425127]


systematic_name: M34243
exact_source: GO:0071896
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071896
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is transported to, and/or maintained at the adherens junction. [GOC:aruk, GOC:bc, GOC:BHF, GOC:mah, PMID:26412237]


systematic_name: M15624
exact_source: GO:0071900
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071900
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity. [GOC:mah]


systematic_name: M16865
exact_source: GO:0071901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity. [GOC:BHF, GOC:mah]


systematic_name: M13485
exact_source: GO:0071902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity. [GOC:mah]


systematic_name: M24529
exact_source: GO:0071907
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071907
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed. [GOC:cvs]


systematic_name: M24530
exact_source: GO:0071910
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071910
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Determination of the asymmetric location of the liver with respect to the left and right halves of the organism. [GOC:cvs]


systematic_name: M42932
exact_source: GO:0071918
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071918
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M48501
exact_source: GO:0071941
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071941
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization. [GOC:mah, PMID:16675690, Wikipedia:Nitrogen_cycle]


systematic_name: M24533
exact_source: GO:0071947
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071947
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism. [GOC:mah]


systematic_name: M46847
exact_source: GO:0071962
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071962
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which centromeres of sister chromatids are joined during mitosis. [GOC:mah]


systematic_name: M24534
exact_source: GO:0071971
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071971
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458]


systematic_name: M13634
exact_source: GO:0071985
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0071985
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded. [GOC:mah, PMID:17603537]


systematic_name: M45915
exact_source: GO:0072001
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072001
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System]


systematic_name: M15872
exact_source: GO:0072006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M42933
exact_source: GO:0072007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


systematic_name: M12799
exact_source: GO:0072009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. [GOC:mtg_kidney_jan10]


systematic_name: M14527
exact_source: GO:0072010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M48502
exact_source: GO:0072011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. [GOC:mtg_kidney_jan10]


systematic_name: M24537
exact_source: GO:0072014
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072014
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. [GOC:mtg_kidney_jan10]


systematic_name: M13821
exact_source: GO:0072017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. [GOC:mtg_kidney_jan10]


systematic_name: M45203
exact_source: GO:0072025
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072025
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. [GOC:mtg_kidney_jan10]


systematic_name: M24539
exact_source: GO:0072028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M24540
exact_source: GO:0072033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. [GOC:mtg_kidney_jan10]


systematic_name: M24541
exact_source: GO:0072038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. [GOC:mtg_kidney_jan10]


systematic_name: M15735
exact_source: GO:0072044
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072044
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. [GOC:mtg_kidney_jan10]


systematic_name: M40501
exact_source: GO:0072047
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072047
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end). [GOC:mtg_kidney_jan10]


systematic_name: M24543
exact_source: GO:0072049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. [GOC:mtg_kidney_jan10]


systematic_name: M24544
exact_source: GO:0072050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. [GOC:mtg_kidney_jan10]


systematic_name: M10785
exact_source: GO:0072070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. [GOC:mtg_kidney_jan10]


systematic_name: M11503
exact_source: GO:0072073
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072073
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. [GOC:mtg_kidney_jan10]


systematic_name: M14682
exact_source: GO:0072074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M14282
exact_source: GO:0072075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M15772
exact_source: GO:0072079
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072079
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M11175
exact_source: GO:0072087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. [GOC:mtg_kidney_jan10]


systematic_name: M11822
exact_source: GO:0072089
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072089
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [GOC:mtg_kidney_jan10]


systematic_name: M14567
exact_source: GO:0072091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. [GOC:mtg_kidney_jan10]


systematic_name: M24545
exact_source: GO:0072102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:mtg_kidney_jan10]


systematic_name: M24546
exact_source: GO:0072103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. [GOC:mtg_kidney_jan10]


systematic_name: M24547
exact_source: GO:0072109
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072109
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. [GOC:mtg_kidney_jan10]


systematic_name: M24548
exact_source: GO:0072110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population. [GOC:mtg_kidney_jan10]


systematic_name: M24549
exact_source: GO:0072111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M24550
exact_source: GO:0072126
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072126
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation. [GOC:mtg_kidney_jan10]


systematic_name: M15995
exact_source: GO:0072132
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072132
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. [GOC:mtg_kidney_jan10]


systematic_name: M24551
exact_source: GO:0072143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


systematic_name: M29277
exact_source: GO:0072144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure. [GOC:mtg_kidney_jan10]


systematic_name: M16390
exact_source: GO:0072148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell. [GOC:mtg_kidney_jan10]


systematic_name: M24552
exact_source: GO:0072160
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072160
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


systematic_name: M24553
exact_source: GO:0072161
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072161
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


systematic_name: M24554
exact_source: GO:0072162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


systematic_name: M48503
exact_source: GO:0072170
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072170
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M13433
exact_source: GO:0072171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. [GOC:mtg_kidney_jan10]


systematic_name: M24555
exact_source: GO:0072172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. [GOC:mtg_kidney_jan10]


systematic_name: M24556
exact_source: GO:0072173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M24557
exact_source: GO:0072174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of a metanephric tubule. [GOC:mtg_kidney_jan10]


systematic_name: M29278
exact_source: GO:0072175
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072175
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of an epithelial tube. [GOC:mtg_kidney_jan10]


systematic_name: M12344
exact_source: GO:0072176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. [GOC:mtg_kidney_jan10]


systematic_name: M24558
exact_source: GO:0072177
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072177
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. [GOC:mtg_kidney_jan10]


systematic_name: M16627
exact_source: GO:0072178
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072178
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. [GOC:mtg_kidney_jan10]


systematic_name: M42934
exact_source: GO:0072179
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072179
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. [GOC:mtg_kidney_jan10]


systematic_name: M10305
exact_source: GO:0072189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. [GOC:mtg_kidney_jan10]


systematic_name: M24560
exact_source: GO:0072197
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072197
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. [GOC:mtg_kidney_jan10]


systematic_name: M24561
exact_source: GO:0072201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:mtg_kidney_jan10]


systematic_name: M11534
exact_source: GO:0072202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state. [GOC:mah, GOC:mtg_kidney_jan10]


systematic_name: M24562
exact_source: GO:0072203
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072203
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M24563
exact_source: GO:0072205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. [GOC:mtg_kidney_jan10]


systematic_name: M10744
exact_source: GO:0072207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. [GOC:mtg_kidney_jan10]


systematic_name: M13904
exact_source: GO:0072210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. [GOC:mtg_kidney_jan10]


systematic_name: M14618
exact_source: GO:0072215
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072215
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:mtg_kidney_jan10]


systematic_name: M24565
exact_source: GO:0072223
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072223
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. [GOC:mtg_kidney_jan10]


systematic_name: M24566
exact_source: GO:0072224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. [GOC:mah]


systematic_name: M24567
exact_source: GO:0072235
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072235
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. [GOC:mtg_kidney_jan10]


systematic_name: M45204
exact_source: GO:0072236
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072236
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M46848
exact_source: GO:0072237
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072237
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. [GOC:mtg_kidney_jan10]


systematic_name: M24569
exact_source: GO:0072239
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072239
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. [GOC:mtg_kidney_jan10]


systematic_name: M24571
exact_source: GO:0072257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state. [GOC:mtg_kidney_jan10]


systematic_name: M10135
exact_source: GO:0072273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M24572
exact_source: GO:0072282
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072282
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M12849
exact_source: GO:0072283
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072283
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. [GOC:mtg_kidney_jan10]


systematic_name: M24573
exact_source: GO:0072284
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072284
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. [GOC:mtg_kidney_jan10]


systematic_name: M24576
exact_source: GO:0072310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. [GOC:mtg_kidney_jan10]


systematic_name: M24578
exact_source: GO:0072319
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072319
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein depolymerization process that results in the disassembly of vesicle coat proteins. [GOC:mah]


systematic_name: M15447
exact_source: GO:0072329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. [GOC:mah]


systematic_name: M14020
exact_source: GO:0072330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. [GOC:mah]


systematic_name: M14109
exact_source: GO:0072331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein. [GOC:mah]


systematic_name: M15049
exact_source: GO:0072332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. [GOC:mah, GOC:mtg_apoptosis]


systematic_name: M10877
exact_source: GO:0072337
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072337
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M42935
exact_source: GO:0072344
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072344
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex. [GOC:jh2, GOC:mah, PMID:18557701, PMID:19170872, PMID:20117091, PMID:20185543]


systematic_name: M13590
exact_source: GO:0072348
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072348
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:mah]


systematic_name: M13081
exact_source: GO:0072350
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072350
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-). [GOC:mah]


systematic_name: M16442
exact_source: GO:0072359
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072359
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. [GOC:mah, UBERON:0001009]


systematic_name: M10315
exact_source: GO:0072376
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072376
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events. [GOC:add, GOC:mah, GOC:pde]


systematic_name: M45916
exact_source: GO:0072378
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072378
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events. [GOC:add, GOC:mah, GOC:pde]


systematic_name: M11482
exact_source: GO:0072384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. [GOC:mah]


systematic_name: M24583
exact_source: GO:0072386
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072386
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. [GOC:BHF, GOC:mah]


systematic_name: M24584
exact_source: GO:0072393
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072393
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center. [GOC:BHF, PMID:19825938]


systematic_name: M24586
exact_source: GO:0072396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling. [GOC:mtg_cell_cycle]


systematic_name: M42936
exact_source: GO:0072488
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072488
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. [GOC:mah]


systematic_name: M24588
exact_source: GO:0072497
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072497
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. [CL:0002452, GOC:BHF]


systematic_name: M14009
exact_source: GO:0072498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure. [GOC:BHF, GOC:vk]


systematic_name: M24590
exact_source: GO:0072520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. [GOC:BHF, GOC:mah, UBERON:0001343]


systematic_name: M15746
exact_source: GO:0072521
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072521
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. [GOC:mah]


systematic_name: M15874
exact_source: GO:0072523
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072523
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. [GOC:mah]


systematic_name: M24591
exact_source: GO:0072524
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072524
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. [GOC:mah]


systematic_name: M34245
exact_source: GO:0072525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. [GOC:mah]


systematic_name: M29280
exact_source: GO:0072526
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072526
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof. [GOC:mah]


systematic_name: M13768
exact_source: GO:0072527
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072527
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. [GOC:mah]


systematic_name: M16659
exact_source: GO:0072528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. [GOC:mah]


systematic_name: M12076
exact_source: GO:0072529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. [GOC:mah]


systematic_name: M24592
exact_source: GO:0072530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof. [GOC:mah]


systematic_name: M14712
exact_source: GO:0072531
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072531
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof. [GOC:mah]


systematic_name: M24593
exact_source: GO:0072537
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072537
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. [CL:0000057, GOC:BHF, GOC:mah]


systematic_name: M24594
exact_source: GO:0072538
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072538
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22. [GOC:BHF, GOC:ebc]


systematic_name: M42937
exact_source: GO:0072539
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072539
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. [CL:0000899, GOC:BHF, GOC:ebc]


systematic_name: M24595
exact_source: GO:0072540
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072540
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. [CL:0000899, GOC:BHF, GOC:ebc]


systematic_name: M42938
exact_source: GO:0072553
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072553
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. [GOC:BHF, GOC:mah]


systematic_name: M34246
exact_source: GO:0072566
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072566
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF, GOC:mah]


systematic_name: M24597
exact_source: GO:0072567
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072567
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF, GOC:mah]


systematic_name: M24599
exact_source: GO:0072577
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072577
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis]


systematic_name: M24600
exact_source: GO:0072578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane. [GOC:dsf, PMID:20843816]


systematic_name: M24601
exact_source: GO:0072583
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072583
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles. [GOC:BHF, GOC:mah, PMID:18498251, PMID:8970738, PMID:9234965]


systematic_name: M24602
exact_source: GO:0072584
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072584
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers. [GOC:BHF, GOC:mah, PMID:17318224, PMID:18498251, PMID:8970738, PMID:9234965]


systematic_name: M15990
exact_source: GO:0072593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. [GOC:mah]


systematic_name: M11490
exact_source: GO:0072594
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072594
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. [GOC:mah]


systematic_name: M13203
exact_source: GO:0072595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. [GOC:mah]


systematic_name: M24614
exact_source: GO:0072656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. [GOC:mah]


systematic_name: M24615
exact_source: GO:0072659
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072659
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. [GOC:mah]


systematic_name: M12847
exact_source: GO:0072665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained at, a location in a vacuole. [GOC:ecd]


systematic_name: M24616
exact_source: GO:0072672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of a neutrophil from the blood vessels into the surrounding tissue. [CL:0000775, GOC:BHF]


systematic_name: M24617
exact_source: GO:0072673
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072673
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized. [GOC:BHF, GOC:mah]


systematic_name: M24618
exact_source: GO:0072674
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072674
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. [CL:0000779, GOC:mah, PMID:12713016]


systematic_name: M24619
exact_source: GO:0072675
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072675
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast. [CL:0000092, CL:0000779, GOC:BHF, GOC:mah, PMID:12713016]


systematic_name: M15399
exact_source: GO:0072676
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072676
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a lymphocyte within or between different tissues and organs of the body. [CL:0000542, GOC:BHF, GOC:mah]


systematic_name: M24620
exact_source: GO:0072677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of an eosinophil within or between different tissues and organs of the body. [CL:0000771, GOC:BHF, GOC:mah]


systematic_name: M14198
exact_source: GO:0072678
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072678
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a T cell within or between different tissues and organs of the body. [CL:0000084, GOC:BHF, GOC:mah]


systematic_name: M24621
exact_source: GO:0072679
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072679
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. [CL:0000893, GOC:BHF, GOC:mah]


systematic_name: M24622
exact_source: GO:0072683
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072683
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The migration of a T cell from the blood vessels into the surrounding tissue. [CL:0000084, GOC:BHF, GOC:mah]


systematic_name: M24624
exact_source: GO:0072708
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072708
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus. [GOC:mah]


systematic_name: M24625
exact_source: GO:0072710
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072710
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus. [GOC:mah]


systematic_name: M42939
exact_source: GO:0072716
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0072716
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus. [GOC:mah]


systematic_name: M34247
exact_source: GO:0075294
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0075294
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. [GOC:pamgo_curators]


systematic_name: M34248
exact_source: GO:0075509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0075509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any endocytosis that is involved in the uptake of a virus into a host cell. [GOC:bf, GOC:jl, VZ:977]


systematic_name: M24630
exact_source: GO:0075522
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0075522
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation. [GOC:bf, GOC:jl, PMID:19632368, VZ:867]


systematic_name: M24631
exact_source: GO:0075525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0075525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF. [GOC:bf, GOC:ch, GOC:jl, PMID:18631147, PMID:18824510, VZ:858]


systematic_name: M42940
exact_source: GO:0075733
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0075733
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a virus, or part of a virus, within the host cell. [GOC:ai, GOC:bf, GOC:jl, PMID:11733033]


systematic_name: M13345
exact_source: GO:0080134
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080134
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:dhl]


systematic_name: M14850
exact_source: GO:0080135
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080135
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:dhl]


systematic_name: M29282
exact_source: GO:0080144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell. [PMID:19955263]


systematic_name: M24633
exact_source: GO:0080154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). [GOC:DHL, PMID:20478994]


systematic_name: M40506
exact_source: GO:0080164
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080164
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water. [GOC:DHL]


systematic_name: M14989
exact_source: GO:0080171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole. [PMID:20729380]


systematic_name: M48506
exact_source: GO:0080184
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0080184
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin. [GOC:tb]


systematic_name: M24634
exact_source: GO:0085020
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0085020
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair. [GOC:sp]


systematic_name: M24635
exact_source: GO:0086002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An action potential that occurs in a cardiac muscle cell and is involved in its contraction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M13694
exact_source: GO:0086003
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086003
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M14176
exact_source: GO:0086005
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086005
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An action potential that occurs in a ventricular cardiac muscle cell. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M15960
exact_source: GO:0086009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M10863
exact_source: GO:0086010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24636
exact_source: GO:0086011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M46849
exact_source: GO:0086012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M46850
exact_source: GO:0086018
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086018
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M13356
exact_source: GO:0086019
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086019
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M42942
exact_source: GO:0086027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24639
exact_source: GO:0086028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24641
exact_source: GO:0086036
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086036
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24642
exact_source: GO:0086042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24643
exact_source: GO:0086045
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086045
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24644
exact_source: GO:0086046
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086046
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24645
exact_source: GO:0086064
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086064
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M12906
exact_source: GO:0086065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M46851
exact_source: GO:0086066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24646
exact_source: GO:0086067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M46852
exact_source: GO:0086068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M10299
exact_source: GO:0086069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24647
exact_source: GO:0086070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M14420
exact_source: GO:0086091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cardiac conduction process that modulates the frequency or rate of heart contraction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M34249
exact_source: GO:0086100
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086100
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by endothelin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:bf, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:10977869]


systematic_name: M24648
exact_source: GO:0086103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0086103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, PMID:17376402]


systematic_name: M42943
exact_source: GO:0089718
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0089718
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. [GOC:krc, PMID:8195186]


systematic_name: M11065
exact_source: GO:0090009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. [GOC:dph, GOC:sdb_2009, GOC:tb]


systematic_name: M29283
exact_source: GO:0090022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding. [GOC:dph, GOC:tb]


systematic_name: M24650
exact_source: GO:0090030
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090030
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. [GOC:dph, GOC:tb]


systematic_name: M45207
exact_source: GO:0090032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. [GOC:dph, GOC:tb]


systematic_name: M14848
exact_source: GO:0090036
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090036
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:dph, GOC:tb]


systematic_name: M24651
exact_source: GO:0090037
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090037
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound. [GOC:dph, GOC:tb]


systematic_name: M24652
exact_source: GO:0090042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12982
exact_source: GO:0090049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


systematic_name: M24655
exact_source: GO:0090050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


systematic_name: M24656
exact_source: GO:0090051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis. [GOC:BHF, GOC:dph, GOC:rl, GOC:tb]


systematic_name: M34251
exact_source: GO:0090063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. [GOC:dph, GOC:tb]


systematic_name: M13340
exact_source: GO:0090068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [GOC:dph, GOC:tb]


systematic_name: M42945
exact_source: GO:0090069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. [GOC:dph, GOC:tb]


systematic_name: M13236
exact_source: GO:0090075
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090075
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain. [GOC:BHF, GOC:rl, PMID:19996365]


systematic_name: M24660
exact_source: GO:0090077
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090077
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M48507
exact_source: GO:0090080
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090080
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade. [GOC:dph, GOC:tb]


systematic_name: M13842
exact_source: GO:0090083
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090083
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M24662
exact_source: GO:0090084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M24663
exact_source: GO:0090085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M34253
exact_source: GO:0090087
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090087
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:tb]


systematic_name: M29284
exact_source: GO:0090090
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090090
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:dph, GOC:tb]


systematic_name: M24664
exact_source: GO:0090091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. [GOC:dph, GOC:tb]


systematic_name: M12865
exact_source: GO:0090092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


systematic_name: M16041
exact_source: GO:0090100
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090100
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


systematic_name: M16180
exact_source: GO:0090101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. [GOC:dph, GOC:tb]


systematic_name: M14694
exact_source: GO:0090102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. [GOC:dph, GOC:tb]


systematic_name: M24665
exact_source: GO:0090110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi. [GOC:ascb_2009, GOC:dph, GOC:lb, GOC:tb]


systematic_name: M24666
exact_source: GO:0090114
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090114
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24667
exact_source: GO:0090118
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090118
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A receptor-mediated endocytosis process involved in intracellular cholesterol transport. [GOC:ascb_2009, GOC:dph, GOC:pr, GOC:tb]


systematic_name: M42947
exact_source: GO:0090119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M16375
exact_source: GO:0090128
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090128
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M12810
exact_source: GO:0090129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M12932
exact_source: GO:0090130
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090130
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the population of cells that make up a tissue undergo directed movement. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24668
exact_source: GO:0090131
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090131
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the population of cells that make up a mesenchyme undergo directed movement. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M12249
exact_source: GO:0090136
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090136
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of an epithelial cell to another epithelial cell via adhesion molecules. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M13263
exact_source: GO:0090140
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090140
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M10378
exact_source: GO:0090141
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090141
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24669
exact_source: GO:0090148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M13481
exact_source: GO:0090150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein to a specific location in a membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24670
exact_source: GO:0090151
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090151
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein to a specific location in the mitochondrial membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24671
exact_source: GO:0090153
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090153
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M29287
exact_source: GO:0090156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M34254
exact_source: GO:0090158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M14362
exact_source: GO:0090161
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090161
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M10706
exact_source: GO:0090162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specification and formation of anisotropic intracellular organization of an epithelial cell. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24674
exact_source: GO:0090166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M15257
exact_source: GO:0090169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M12989
exact_source: GO:0090174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The joining of two lipid bilayers to form a single organelle membrane. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M42948
exact_source: GO:0090175
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090175
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24675
exact_source: GO:0090177
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090177
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M40508
exact_source: GO:0090179
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090179
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M15312
exact_source: GO:0090181
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090181
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12397
exact_source: GO:0090183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M10982
exact_source: GO:0090184
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090184
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M42949
exact_source: GO:0090185
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090185
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M24676
exact_source: GO:0090186
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090186
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. [GOC:dph, GOC:tb]


systematic_name: M48508
exact_source: GO:0090188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M40509
exact_source: GO:0090189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M42950
exact_source: GO:0090192
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090192
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M45208
exact_source: GO:0090193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M13355
exact_source: GO:0090199
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090199
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M11859
exact_source: GO:0090200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M13583
exact_source: GO:0090201
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090201
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M29289
exact_source: GO:0090205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M29290
exact_source: GO:0090206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M10533
exact_source: GO:0090207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M29291
exact_source: GO:0090208
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090208
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M29292
exact_source: GO:0090209
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090209
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M12780
exact_source: GO:0090224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M46854
exact_source: GO:0090230
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090230
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M48509
exact_source: GO:0090231
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090231
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M48510
exact_source: GO:0090232
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090232
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24683
exact_source: GO:0090235
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090235
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle. [GOC:ascb_2009, GOC:dph, GOC:tb]


systematic_name: M24684
exact_source: GO:0090237
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090237
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue. [GOC:dph, GOC:tb]


systematic_name: M15722
exact_source: GO:0090257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. [GOC:dph, GOC:tb]


systematic_name: M14526
exact_source: GO:0090263
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090263
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. [GOC:tb]


systematic_name: M24690
exact_source: GO:0090269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


systematic_name: M34256
exact_source: GO:0090272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:BHF]


systematic_name: M12968
exact_source: GO:0090279
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090279
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


systematic_name: M14471
exact_source: GO:0090280
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090280
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


systematic_name: M12702
exact_source: GO:0090281
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090281
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle. [GOC:BHF]


systematic_name: M10257
exact_source: GO:0090287
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090287
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:tb]


systematic_name: M12333
exact_source: GO:0090288
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090288
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus. [GOC:BHF]


systematic_name: M45209
exact_source: GO:0090289
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090289
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. [GOC:tb]


systematic_name: M14541
exact_source: GO:0090303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. [GOC:BHF]


systematic_name: M24697
exact_source: GO:0090306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis. [GOC:tb, GOC:vw]


systematic_name: M12435
exact_source: GO:0090307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied. [GOC:tb, GOC:vw]


systematic_name: M24698
exact_source: GO:0090308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation. [GOC:BHF]


systematic_name: M24699
exact_source: GO:0090309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation. [GOC:BHF]


systematic_name: M10897
exact_source: GO:0090311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:tb]


systematic_name: M14870
exact_source: GO:0090312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:ecd, PMID:20027304]


systematic_name: M11502
exact_source: GO:0090313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:tb]


systematic_name: M16470
exact_source: GO:0090314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:tb]


systematic_name: M24700
exact_source: GO:0090315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:tb]


systematic_name: M10915
exact_source: GO:0090316
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090316
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. [GOC:tb]


systematic_name: M12270
exact_source: GO:0090317
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090317
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. [GOC:tb]


systematic_name: M14788
exact_source: GO:0090322
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090322
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. [GOC:tb]


systematic_name: M42955
exact_source: GO:0090325
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090325
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. [GOC:dph, GOC:kmv, GOC:tb]


systematic_name: M10569
exact_source: GO:0090329
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090329
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized. [GOC:dph, GOC:tb]


systematic_name: M12339
exact_source: GO:0090330
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090330
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:dph, GOC:tb]


systematic_name: M46855
exact_source: GO:0090331
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090331
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:BHF]


systematic_name: M11381
exact_source: GO:0090335
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090335
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. [GOC:tb]


systematic_name: M24704
exact_source: GO:0090336
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090336
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. [GOC:BHF]


systematic_name: M24706
exact_source: GO:0090370
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090370
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle. [GOC:dph, GOC:tb, GOC:yaf]


systematic_name: M12757
exact_source: GO:0090382
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090382
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. [GOC:kmv, GOC:tb]


systematic_name: M13530
exact_source: GO:0090383
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090383
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion. [GOC:kmv, GOC:tb]


systematic_name: M24709
exact_source: GO:0090394
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090394
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. [GOC:BHF]


systematic_name: M11558
exact_source: GO:0090398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest. [GOC:BHF, PMID:28682291]


systematic_name: M14683
exact_source: GO:0090399
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090399
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging. [GOC:BHF]


systematic_name: M24710
exact_source: GO:0090400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays. [GOC:BHF]


systematic_name: M46856
exact_source: GO:0090402
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090402
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family. [GOC:BHF]


systematic_name: M11681
exact_source: GO:0090407
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090407
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. [GOC:chem_mtg]


systematic_name: M45917
exact_source: GO:0090425
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090425
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. [GOC:dph, GOC:tb]


systematic_name: M24711
exact_source: GO:0090435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. [GOC:tb]


systematic_name: M40510
exact_source: GO:0090461
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090461
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell. [GOC:tb]


systematic_name: M45210
exact_source: GO:0090497
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090497
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. [GOC:dph, GOC:tb]


systematic_name: M42957
exact_source: GO:0090500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:dph, GOC:tb]


systematic_name: M40511
exact_source: GO:0090521
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090521
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. [GOC:pm, PMID:21402783]


systematic_name: M45211
exact_source: GO:0090522
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090522
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. [GOC:rn, PMID:10559876, PMID:17052174, PMID:17488620, PMID:22420621, PMID:27243008]


systematic_name: M10692
exact_source: GO:0090557
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090557
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition. [GOC:krc, PMID:22155109]


systematic_name: M15860
exact_source: GO:0090559
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090559
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane. [GOC:kmv, PMID:22677064]


systematic_name: M24714
exact_source: GO:0090594
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090594
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. [GOC:add]


systematic_name: M15276
exact_source: GO:0090596
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090596
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:kmv, ISBN:978-0199210893]


systematic_name: M24715
exact_source: GO:0090611
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090611
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination. [PMID:22547407]


systematic_name: M10929
exact_source: GO:0090630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP. [GOC:dph, GOC:mah, GOC:tb]


systematic_name: M24716
exact_source: GO:0090646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion. [GOC:vw]


systematic_name: M24718
exact_source: GO:0090649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose. [GOC:sl, PMID:21525936]


systematic_name: M24719
exact_source: GO:0090657
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090657
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication. [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:22579284]


systematic_name: M16566
exact_source: GO:0090659
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090659
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg. [GOC:tb]


systematic_name: M34258
exact_source: GO:0090660
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090660
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional. [GOC:mgi_curators, PMID:22100360, PMID:24229449]


systematic_name: M24720
exact_source: GO:0090666
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090666
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body. [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444]


systematic_name: M24721
exact_source: GO:0090672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which telomerase RNA is transported to, or maintained in, a specific location. [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:25467444]


systematic_name: M24722
exact_source: GO:0090673
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090673
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The binding of an endothelial cell to the extracellular matrix via adhesion molecules. [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:19460962]


systematic_name: M24723
exact_source: GO:0090677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another. [GOC:curators]


systematic_name: M24724
exact_source: GO:0090679
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090679
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. [GOC:curators]


systematic_name: M24725
exact_source: GO:0090713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. [GOC:add, PMID:26086132, PMID:26831526]


systematic_name: M24726
exact_source: GO:0090715
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090715
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any immunological memory process that can contribute to the formation of immunological memory. [GOC:add, PMID:26086132, PMID:26831526]


systematic_name: M48511
exact_source: GO:0090716
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0090716
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response. [GOC:add, PMID:26831526]


systematic_name: M14600
exact_source: GO:0097006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism. [GOC:BHF]


systematic_name: M14714
exact_source: GO:0097009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the balance between food intake (energy input) and energy expenditure. [GOC:yaf, PMID:15919751]


systematic_name: M24728
exact_source: GO:0097012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus. [GOC:pr]


systematic_name: M42959
exact_source: GO:0097017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). [GOC:yaf, PMID:18431508]


systematic_name: M46857
exact_source: GO:0097018
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097018
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. [GOC:yaf, PMID:18431508]


systematic_name: M34260
exact_source: GO:0097021
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097021
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen. [GOC:BHF, GOC:pr, PMID:18379575]


systematic_name: M10358
exact_source: GO:0097028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. [CL:0000451, GOC:pr]


systematic_name: M42960
exact_source: GO:0097029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. [GOC:BHF, http://www.rndsystems.com/mini_review_detail_objectname_MR02_DendriticCellMat.aspx, PMID:15845453]


systematic_name: M11676
exact_source: GO:0097035
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097035
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane. [GOC:mah, PMID:18441123, PMID:20823909]


systematic_name: M24729
exact_source: GO:0097039
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097039
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein. [GOC:jsg, GOC:sp, PMID:21455173, PMID:21455180, PMID:21455181]


systematic_name: M24730
exact_source: GO:0097048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845]


systematic_name: M24731
exact_source: GO:0097049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086]


systematic_name: M24732
exact_source: GO:0097050
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097050
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305]


systematic_name: M29295
exact_source: GO:0097052
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097052
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine). [GOC:yaf]


systematic_name: M24733
exact_source: GO:0097062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission. [GOC:BHF, PMID:20410104]


systematic_name: M24735
exact_source: GO:0097065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure. [GOC:yaf, PMID:14695376, PMID:15857913]


systematic_name: M15044
exact_source: GO:0097066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. [GOC:sjw, PMID:9916872]


systematic_name: M13357
exact_source: GO:0097067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. [GOC:sjw, PMID:9916872]


systematic_name: M42961
exact_source: GO:0097068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus. [GOC:sjw, PMID:9916872]


systematic_name: M24736
exact_source: GO:0097070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs. [GOC:hw]


systematic_name: M24737
exact_source: GO:0097084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. [GOC:BHF]


systematic_name: M24738
exact_source: GO:0097090
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097090
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction. [GOC:BHF, GOC:pr, GOC:sjp, PMID:19730411]


systematic_name: M24739
exact_source: GO:0097091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that results in grouping synaptic vesicles in presynaptic structures. [GOC:ans, GOC:pr, PMID:19900895, PMID:7568108]


systematic_name: M15587
exact_source: GO:0097094
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097094
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which any suture between cranial and/or facial bones is generated and organized. [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system]


systematic_name: M24740
exact_source: GO:0097104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). [GOC:BHF, GOC:sjp, PMID:21424692]


systematic_name: M45918
exact_source: GO:0097107
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097107
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. [GOC:BHF, GOC:sjp, PMID:21525273]


systematic_name: M24743
exact_source: GO:0097113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane. [GOC:BHF, GOC:pr, GOC:sjp, PMID:12796785]


systematic_name: M42962
exact_source: GO:0097116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses. [GOC:BHF, GOC:sjp, PMID:15620359, PMID:24552784, PMID:25772192]


systematic_name: M24744
exact_source: GO:0097119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. [GOC:BHF, GOC:sjp, PMID:10433269]


systematic_name: M24745
exact_source: GO:0097120
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097120
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. [GOC:BHF, GOC:sjp, PMID:21525273]


systematic_name: M14286
exact_source: GO:0097150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in by an organism or tissue maintains a population of neuronal stem cells. [CL:0000047, GOC:dos, GOC:yaf, PMID:11399758]


systematic_name: M24747
exact_source: GO:0097152
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097152
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833]


systematic_name: M11870
exact_source: GO:0097154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. [GOC:kmv, PMID:11517269]


systematic_name: M24748
exact_source: GO:0097168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. [CL:0000134, GOC:yaf, PMID:20626275]


systematic_name: M34261
exact_source: GO:0097176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. [GOC:rs, PMID:15822179]


systematic_name: M24749
exact_source: GO:0097178
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097178
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. [GOC:yaf, http:en.wikipedia.org/wiki/Membrane_ruffling, PMID:12556481]


systematic_name: M14160
exact_source: GO:0097186
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097186
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346]


systematic_name: M24750
exact_source: GO:0097187
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097187
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346]


systematic_name: M12660
exact_source: GO:0097190
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097190
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. [GOC:mtg_apoptosis]


systematic_name: M11317
exact_source: GO:0097191
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097191
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. [GOC:mtg_apoptosis, GOC:yaf, PMID:17340152]


systematic_name: M13922
exact_source: GO:0097193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP). [GOC:mtg_apoptosis, GOC:yaf, PMID:11919192, PMID:17340152, PMID:18852119]


systematic_name: M15953
exact_source: GO:0097194
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097194
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:mtg_apoptosis, PMID:21760595]


systematic_name: M11815
exact_source: GO:0097202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. [GOC:mtg_apoptosis, PMID:21726810]


systematic_name: M16139
exact_source: GO:0097205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A renal system process in which fluid circulating through the body is filtered through a barrier system. [GOC:pr, GOC:sart]


systematic_name: M24752
exact_source: GO:0097210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus. [GOC:yaf, PMID:15976007]


systematic_name: M40513
exact_source: GO:0097212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. [GOC:yaf, PMID:20544854]


systematic_name: M12658
exact_source: GO:0097237
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097237
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. [GOC:pr]


systematic_name: M42963
exact_source: GO:0097241
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097241
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. [CL:0000037, GOC:yaf, PMID:17368745]


systematic_name: M24753
exact_source: GO:0097242
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097242
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors. [GOC:aruk, GOC:bc, GOC:BHF, PMID:18289866, PMID:19098903, PMID:26005850]


systematic_name: M34262
exact_source: GO:0097250
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097250
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex. [GOC:mcc, PMID:21909073, PMID:22342701]


systematic_name: M48512
exact_source: GO:0097252
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097252
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. [CL:0000128, GOC:mtg_apoptosis, GOC:yaf, PMID:16723520]


systematic_name: M42964
exact_source: GO:0097254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion]


systematic_name: M24754
exact_source: GO:0097264
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097264
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds. [GOC:yaf, PMID:18676612, PMID:19144634]


systematic_name: M24755
exact_source: GO:0097267
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097267
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation. [GOC:mw, PMID:10681399]


systematic_name: M45212
exact_source: GO:0097272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process involved in the maintenance of an internal steady state of ammonium. [GOC:yaf, PMID:12695560]


systematic_name: M29297
exact_source: GO:0097278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Cell killing caused by the membrane attack complex formed following complement activation. [GOC:add, GOC:rv]


systematic_name: M24756
exact_source: GO:0097283
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097283
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. [CL:0000312, GOC:jc, GOC:mtg_apoptosis, PMID:10201527]


systematic_name: M13149
exact_source: GO:0097284
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097284
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in a hepatocyte, the main structural component of the liver. [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020]


systematic_name: M24757
exact_source: GO:0097300
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097300
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors. [GOC:mtg_apoptosis, PMID:21760595]


systematic_name: M16155
exact_source: GO:0097305
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097305
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. [GOC:pr, PMID:24014527]


systematic_name: M14879
exact_source: GO:0097306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. [GOC:pr]


systematic_name: M24758
exact_source: GO:0097320
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097320
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A membrane tubulation process occurring in a plasma membrane. [GOC:BHF, GOC:pr, PMID:15252009, PMID:20730103]


systematic_name: M42966
exact_source: GO:0097325
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097325
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. [CL:0000148, GOC:uh, PMID:22637532]


systematic_name: M24761
exact_source: GO:0097341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that prevents the proteolytic processing of an inactive enzyme to an active form. [GOC:mtg_apoptosis, PMID:20383739]


systematic_name: M24762
exact_source: GO:0097345
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097345
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway. [GOC:BHF, GOC:mtg_apoptosis, GOC:pg, PMID:21041309]


systematic_name: M42967
exact_source: GO:0097350
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097350
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms. [GOC:BHF, PMID:21957127]


systematic_name: M24764
exact_source: GO:0097352
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097352
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling. [GOC:autophagy, GOC:lf, PMID:28077293]


systematic_name: M24765
exact_source: GO:0097354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added. [GOC:di, PMID:18029206, PMID:21351751, PMID:22123822, PMID:22642693, PMID:22660767]


systematic_name: M29298
exact_source: GO:0097360
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097360
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population. [CL:0011101, GOC:BHF, PMID:15150278]


systematic_name: M46859
exact_source: GO:0097368
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097368
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions. [GOC:sl, PMID:19509333, Wikipedia:Blood-testis_barrier]


systematic_name: M46860
exact_source: GO:0097384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells. [GOC:pr]


systematic_name: M24769
exact_source: GO:0097396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus. [GOC:pr]


systematic_name: M45213
exact_source: GO:0097400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by interleukin-17 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ic, PMID:21602493]


systematic_name: M45919
exact_source: GO:0097401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading. [GOC:dsf, PMID:21172605, PMID:22875945]


systematic_name: M45920
exact_source: GO:0097402
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097402
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. [CL:0000031, GOC:jc, PMID:15543145]


systematic_name: M24770
exact_source: GO:0097411
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097411
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia. [GOC:bf, GOC:jc, http://www.sabiosciences.com/pathway.php?sn=HIF1Alpha_Pathway]


systematic_name: M24771
exact_source: GO:0097428
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097428
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein. [GOC:al, GOC:mah, PMID:11939799, PMID:18322036, PMID:21977977]


systematic_name: M24772
exact_source: GO:0097435
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097435
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. [GOC:pr]


systematic_name: M40515
exact_source: GO:0097466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component. [GOC:al, GOC:bf, PMID:16079177]


systematic_name: M24773
exact_source: GO:0097468
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097468
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. [GOC:mtg_apoptosis]


systematic_name: M24774
exact_source: GO:0097475
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097475
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. [CL:0000100, GOC:yaf, PMID:20711475]


systematic_name: M10129
exact_source: GO:0097479
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097479
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location. [GOC:pr]


systematic_name: M48513
exact_source: GO:0097485
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097485
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues. [GOC:BHF, GOC:rl, PMID:22790009]


systematic_name: M46861
exact_source: GO:0097490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite. [GOC:BHF, GOC:rl, PMID:22790009]


systematic_name: M24776
exact_source: GO:0097499
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097499
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. [GOC:cilia, GOC:kmv, PMID:23128241]


systematic_name: M34263
exact_source: GO:0097500
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097500
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium. [GOC:cilia, GOC:kmv, PMID:23128241]


systematic_name: M24779
exact_source: GO:0097527
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097527
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered. [GOC:mtg_apoptosis, PMID:20823910]


systematic_name: M10503
exact_source: GO:0097529
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097529
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a myeloid leukocyte within or between different tissues and organs of the body. [GOC:cvs, PMID:22342843, PMID:24157461]


systematic_name: M13368
exact_source: GO:0097530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a granulocyte within or between different tissues and organs of the body. [GOC:cvs, PMID:24163421, PMID:24193336]


systematic_name: M24780
exact_source: GO:0097531
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097531
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The movement of a mast cell within or between different tissues and organs of the body. [GOC:cvs, PMID:24152847]


systematic_name: M45214
exact_source: GO:0097553
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097553
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore. [GOC:vw]


systematic_name: M45215
exact_source: GO:0097576
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097576
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. [GOC:pr, GOC:vw, Wikipedia:Vacuole]


systematic_name: M24782
exact_source: GO:0097577
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097577
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of binding or confining iron ions such that they are separated from other components of a biological system. [GOC:mr, PMID:3099306]


systematic_name: M14411
exact_source: GO:0097581
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097581
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments. [GOC:als, PMID:16054028]


systematic_name: M24783
exact_source: GO:0097623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region. [GOC:vw, PMID:11932440]


systematic_name: M34264
exact_source: GO:0097638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol. [GOC:krc, PMID:8195186]


systematic_name: M24784
exact_source: GO:0097646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:bhm, PMID:10871296, PMID:12037140, PMID:18687416]


systematic_name: M29301
exact_source: GO:0097680
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097680
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining). [GOC:rph, PMID:18584027]


systematic_name: M48514
exact_source: GO:0097681
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097681
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment. [GOC:rph, PMID:18584027, PMID:21655080, Wikipedia:Microhomology-mediated_end_joining]


systematic_name: M24785
exact_source: GO:0097696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins. [GOC:rjd, PMID:21534947, PMID:24587195]


systematic_name: M46862
exact_source: GO:0097707
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097707
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes. [GOC:mtg_apoptosis, PMID:25236395, PMID:26794443]


systematic_name: M24786
exact_source: GO:0097709
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097709
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared. [GOC:bc, GOC:BHF, GOC:BHF_miRNA, PMID:25590961]


systematic_name: M24788
exact_source: GO:0097720
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097720
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression. [GOC:di, PMID:25655284, PMID:25878052, PMID:26851544]


systematic_name: M24789
exact_source: GO:0097742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects. [GOC:cilia, PMID:25047614, PMID:25291643]


systematic_name: M48515
exact_source: GO:0097749
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0097749
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules). [GOC:pr]


systematic_name: M24793
exact_source: GO:0098528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. [GOC:dos]


systematic_name: M46863
exact_source: GO:0098535
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098535
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. [GOC:cilia, GOC:dos, PMID:24075808, PMID:5111878, PMID:5661997]


systematic_name: M12514
exact_source: GO:0098542
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098542
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. [GOC:dos]


systematic_name: M11462
exact_source: GO:0098543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a stimulus from another organism is received and converted into a molecular signal. [GOC:dos]


systematic_name: M24795
exact_source: GO:0098581
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098581
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated. [GOC:dos]


systematic_name: M10352
exact_source: GO:0098586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:dos]


systematic_name: M42969
exact_source: GO:0098597
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098597
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Learning that occurs through observing the behavior of others. [GOC:dos, Wikipedia:Observational_learning&oldid=603524137]


systematic_name: M24797
exact_source: GO:0098598
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098598
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned. [GOC:BHF, GOC:dos, GOC:rl, PMID:16418265, PMID:17035521]


systematic_name: M24798
exact_source: GO:0098655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. [GOC:dos, GOC:vw]


systematic_name: M15727
exact_source: GO:0098657
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098657
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. [GOC:dos]


systematic_name: M46864
exact_source: GO:0098664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. [GOC:mah]


systematic_name: M24801
exact_source: GO:0098696
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098696
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane. [GOC:dos]


systematic_name: M24802
exact_source: GO:0098698
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098698
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane. [GOC:dos]


systematic_name: M24803
exact_source: GO:0098700
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098700
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps. [GOC:bf, GOC:pad, GOC:PARL, PMID:10099709, PMID:15217342]


systematic_name: M45218
exact_source: GO:0098703
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098703
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M34266
exact_source: GO:0098704
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098704
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M34267
exact_source: GO:0098708
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098708
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M34268
exact_source: GO:0098711
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098711
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol. [GOC:mah, PMID:8321236]


systematic_name: M40518
exact_source: GO:0098712
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098712
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M24804
exact_source: GO:0098719
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098719
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M13800
exact_source: GO:0098727
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098727
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process by which the numbers of cells of a particular type or in a tissue are maintained. [GOC:dos]


systematic_name: M11076
exact_source: GO:0098732
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098732
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule. [GOC:dos]


systematic_name: M24807
exact_source: GO:0098735
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098735
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the force of heart muscle contraction. [GOC:BHF, GOC:dos, GOC:mtg_cardiac_conduct_nov11, GOC:rl, PMID:17242280]


systematic_name: M24808
exact_source: GO:0098739
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098739
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. [GOC:dos]


systematic_name: M16429
exact_source: GO:0098742
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098742
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane. [GOC:dos]


systematic_name: M13025
exact_source: GO:0098743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation. [GOC:dos]


systematic_name: M11179
exact_source: GO:0098751
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098751
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. [GOC:dos]


systematic_name: M13476
exact_source: GO:0098754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. [GOC:dos]


systematic_name: M24809
exact_source: GO:0098760
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098760
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus. [GOC:BHF, GOC:mah]


systematic_name: M45921
exact_source: GO:0098771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. [GOC:dos]


systematic_name: M34270
exact_source: GO:0098773
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098773
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. [GOC:dos]


systematic_name: M40519
exact_source: GO:0098779
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098779
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization. [GOC:PARL, PMID:18200046, PMID:23985961]


systematic_name: M24810
exact_source: GO:0098780
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098780
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria. [GOC:dos]


systematic_name: M11496
exact_source: GO:0098792
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098792
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective degradation of intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) by macroautophagy. [GOC:autophagy, GOC:pad, GOC:PARL, PMID:19802565, PMID:20159618, PMID:25497060]


systematic_name: M15521
exact_source: GO:0098801
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098801
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. [GOC:dos]


systematic_name: M24812
exact_source: GO:0098810
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098810
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol. [GOC:dos]


systematic_name: M16660
exact_source: GO:0098813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. [GOC:dos]


systematic_name: M24813
exact_source: GO:0098814
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098814
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential. [PMID:20200227]


systematic_name: M13703
exact_source: GO:0098815
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098815
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential. [GOC:dos]


systematic_name: M45922
exact_source: GO:0098828
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098828
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential. [GOC:dos]


systematic_name: M24814
exact_source: GO:0098838
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098838
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane. [PMID:24745983]


systematic_name: M24815
exact_source: GO:0098856
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098856
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which lipids are taken up from the contents of the intestine. [GOC:dos, GOC:sl, PMID:18768481]


systematic_name: M34271
exact_source: GO:0098869
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098869
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. [GOC:dos, GOC:vw]


systematic_name: M24816
exact_source: GO:0098876
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098876
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. [GOC:dos]


systematic_name: M40520
exact_source: GO:0098877
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098877
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. [GOC:dos]


systematic_name: M42971
exact_source: GO:0098880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process which maintains the organization and the arrangement of proteins in the presynaptic specialization. [GOC:dos]


systematic_name: M24819
exact_source: GO:0098883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190]


systematic_name: M24820
exact_source: GO:0098884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle. [GOC:dos]


systematic_name: M42972
exact_source: GO:0098887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles. [GOC:dos]


systematic_name: M13868
exact_source: GO:0098900
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098900
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8]


systematic_name: M13362
exact_source: GO:0098901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:dos, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24822
exact_source: GO:0098902
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098902
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential. [GOC:dos, GOC:dph, GOC:tb, ISBN:978-0-07-139011-8]


systematic_name: M24823
exact_source: GO:0098903
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098903
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential. [GOC:dos, GOC:dph, GOC:tb, ISBN:978-0-07-139011-8]


systematic_name: M24824
exact_source: GO:0098908
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098908
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:dph, GOC:isa_complete, GOC:tb]


systematic_name: M24825
exact_source: GO:0098909
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098909
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M12329
exact_source: GO:0098911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]


systematic_name: M24827
exact_source: GO:0098914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. [GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb]


systematic_name: M24828
exact_source: GO:0098915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential. [GOC:BHF, GOC:dph, GOC:mtg_cardiac_conduct_nov11, GOC:tb]


systematic_name: M45923
exact_source: GO:0098920
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098920
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. [GOC:dos]


systematic_name: M14502
exact_source: GO:0098927
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098927
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome. [GOC:dos, PMID:10930469]


systematic_name: M24834
exact_source: GO:0098937
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098937
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. [ISBN:0815316194]


systematic_name: M24835
exact_source: GO:0098943
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098943
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation. [GOC:dos]


systematic_name: M24836
exact_source: GO:0098953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix. [PMID:18832033]


systematic_name: M34274
exact_source: GO:0098957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. [GOC:dos]


systematic_name: M46865
exact_source: GO:0098961
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098961
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. [GOC:dos]


systematic_name: M24837
exact_source: GO:0098962
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098962
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. [GOC:dos]


systematic_name: M42974
exact_source: GO:0098971
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0098971
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. [GOC:dos]


systematic_name: M45924
exact_source: GO:0099011
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099011
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels. [GOC:kmv, PMID:17553987, PMID:24653208]


systematic_name: M24843
exact_source: GO:0099022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion. [PMID:27243008]


systematic_name: M29303
exact_source: GO:0099041
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099041
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion. [PMID:27243008]


systematic_name: M24844
exact_source: GO:0099068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a postsynapse. [GOC:bf, GOC:dos, GOCL:PARL]


systematic_name: M24845
exact_source: GO:0099072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. [GOC:dos]


systematic_name: M24846
exact_source: GO:0099084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane. [GOC:BHF, GOC:sjp, PMID:21525273, PMID:26834556]


systematic_name: M45925
exact_source: GO:0099105
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099105
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel. [GOC:dos]


systematic_name: M29304
exact_source: GO:0099111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. [GOC:cjm, ISBN:0815316194]


systematic_name: M24847
exact_source: GO:0099116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA. [GOC:dos, GOC:pf, PMID:27484477]


systematic_name: M24849
exact_source: GO:0099149
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099149
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse. [GOC:ai]


systematic_name: M24850
exact_source: GO:0099150
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0099150
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization. [GOC:dos]


