# gene_set_details

systematic_name: M13218
exact_source: GO:0006012
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006012
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. [ISBN:0198506732]


systematic_name: M22366
exact_source: GO:0006013
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006013
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. [ISBN:0198506732]


systematic_name: M13490
exact_source: GO:0006020
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006020
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. [ISBN:0198547684]


systematic_name: M13402
exact_source: GO:0006022
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006022
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. [GOC:ai, ISBN:0198506732]


systematic_name: M11847
exact_source: GO:0006023
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006023
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. [GOC:ai, ISBN:0198506732]


systematic_name: M16015
exact_source: GO:0006026
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006026
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. [GOC:ai, ISBN:0198506732]


systematic_name: M42620
exact_source: GO:0006027
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006027
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. [ISBN:0192800981]


systematic_name: M880
exact_source: GO:0006029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. [GOC:mah, ISBN:0198506732]


systematic_name: M34062
exact_source: GO:0006030
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006030
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. [GOC:jl, ISBN:0198506732]


systematic_name: M13955
exact_source: GO:0006040
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006040
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. [GOC:jl, ISBN:0192801023]


systematic_name: M18664
exact_source: GO:0006044
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006044
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein. [ISBN:0198506732]


systematic_name: M15333
exact_source: GO:0006047
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006047
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. [GOC:ai]


systematic_name: M22368
exact_source: GO:0006048
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006048
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate. [GOC:ai]


systematic_name: M29024
exact_source: GO:0006054
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006054
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid. [ISBN:0198506732]


systematic_name: M14675
exact_source: GO:0006063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose. [ISBN:0198506732]


systematic_name: M17063
exact_source: GO:0006066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. [ISBN:0198506732]


systematic_name: M29025
exact_source: GO:0006067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation. [GOC:ai, ISBN:0198506732]


systematic_name: M29027
exact_source: GO:0006072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol. [GOC:go_curators, ISBN:0198506732]


systematic_name: M14307
exact_source: GO:0006081
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006081
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. [GOC:go_curators, ISBN:0198506732]


systematic_name: M14117
exact_source: GO:0006082
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006082
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. [ISBN:0198506732]


systematic_name: M11586
exact_source: GO:0006084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis. [ISBN:0198547684]


systematic_name: M14802
exact_source: GO:0006085
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006085
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated. [GOC:go_curators]


systematic_name: M22370
exact_source: GO:0006086
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006086
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M1210
exact_source: GO:0006091
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006091
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. [GOC:jl]


systematic_name: M22373
exact_source: GO:0006099
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006099
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. [ISBN:0198506732]


systematic_name: M29029
exact_source: GO:0006101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle. [ISBN:0198506732]


systematic_name: M22374
exact_source: GO:0006102
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006102
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle. [ISBN:0198506732]


systematic_name: M15857
exact_source: GO:0006103
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006103
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism. [ISBN:0198506732]


systematic_name: M22375
exact_source: GO:0006104
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006104
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A. [GOC:ai]


systematic_name: M22376
exact_source: GO:0006105
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006105
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle. [ISBN:0198506732]


systematic_name: M11435
exact_source: GO:0006107
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006107
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle. [ISBN:0198506732]


systematic_name: M22377
exact_source: GO:0006108
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006108
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. [ISBN:0198506732]


systematic_name: M12731
exact_source: GO:0006109
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006109
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. [GOC:go_curators]


systematic_name: M16528
exact_source: GO:0006111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. [GOC:go_curators]


systematic_name: M18828
exact_source: GO:0006112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. [GOC:mah]


systematic_name: M42623
exact_source: GO:0006113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP). [GOC:curators, ISBN:0201090910, MetaCyc:Fermentation]


systematic_name: M40338
exact_source: GO:0006116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD+. [GOC:ai]


systematic_name: M12919
exact_source: GO:0006119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. [ISBN:0198506732, ISBN:0471331309]


systematic_name: M22379
exact_source: GO:0006120
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006120
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation. [ISBN:0716731363]


systematic_name: M45063
exact_source: GO:0006121
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006121
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. [ISBN:0716731363]


systematic_name: M12278
exact_source: GO:0006122
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006122
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. [ISBN:0716731363]


systematic_name: M40339
exact_source: GO:0006123
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006123
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV. [ISBN:0716731363]


systematic_name: M15679
exact_source: GO:0006140
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006140
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. [GOC:go_curators]


systematic_name: M14439
exact_source: GO:0006144
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006144
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. [GOC:go_curators]


systematic_name: M14480
exact_source: GO:0006152
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006152
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:go_curators]


systematic_name: M22380
exact_source: GO:0006166
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006166
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis. [GOC:jl]


systematic_name: M22381
exact_source: GO:0006167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate. [GOC:go_curators, ISBN:0198506732]


systematic_name: M11264
exact_source: GO:0006171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). [ISBN:0198506732]


systematic_name: M22382
exact_source: GO:0006172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate. [GOC:ai]


systematic_name: M42624
exact_source: GO:0006177
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006177
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate. [ISBN:0198506732]


systematic_name: M10878
exact_source: GO:0006182
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006182
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate. [ISBN:0198506732]


systematic_name: M22383
exact_source: GO:0006183
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006183
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate. [ISBN:0198506732]


systematic_name: M16175
exact_source: GO:0006188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate. [ISBN:0198506732]


systematic_name: M42626
exact_source: GO:0006196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate. [ISBN:0198506732]


systematic_name: M22385
exact_source: GO:0006198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). [ISBN:0198506732]


systematic_name: M42627
exact_source: GO:0006204
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006204
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate. [ISBN:0198506732]


systematic_name: M11748
exact_source: GO:0006206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. [GOC:go_curators]


systematic_name: M22386
exact_source: GO:0006207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors. [GOC:mah, ISBN:0716720094]


systematic_name: M42628
exact_source: GO:0006208
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006208
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases. [GOC:go_curators]


systematic_name: M15692
exact_source: GO:0006213
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006213
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). [GOC:jl, ISBN:0140512713]


systematic_name: M12372
exact_source: GO:0006220
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006220
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M46724
exact_source: GO:0006221
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006221
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40341
exact_source: GO:0006228
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006228
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate. [ISBN:0198506732]


systematic_name: M12633
exact_source: GO:0006244
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006244
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42629
exact_source: GO:0006249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate. [ISBN:0198506732]


systematic_name: M17815
exact_source: GO:0006259
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006259
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. [ISBN:0198506732]


systematic_name: M16148
exact_source: GO:0006260
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006260
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. [GOC:mah]


systematic_name: M18074
exact_source: GO:0006261
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006261
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. [GOC:mah, ISBN:0198506732]


systematic_name: M22391
exact_source: GO:0006265
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006265
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. [ISBN:071673706X, ISBN:0935702490]


systematic_name: M15868
exact_source: GO:0006266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase. [ISBN:0815316194]


systematic_name: M22392
exact_source: GO:0006268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. [ISBN:071673706X, ISBN:0815316194]


systematic_name: M22393
exact_source: GO:0006269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of a short nucleotide polymer using one strand of unwound DNA as a template. The product is usually a RNA molecule between 4-15 nucleotides long that provides a free 3'-OH that can be extended by DNA-directed DNA polymerases. In certain conditions, for example in response to DNA damage, some primases synthesize a DNA primer. [PMID:11395402, PMID:38203225, PMID:38492718]


systematic_name: M3528
exact_source: GO:0006270
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006270
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding. [PMID:28209641]


systematic_name: M11000
exact_source: GO:0006271
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006271
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. [GOC:mah, ISBN:071673706X, ISBN:0815316194]


systematic_name: M10089
exact_source: GO:0006278
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006278
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand. [GOC:mah, ISBN:0198506732]


systematic_name: M18229
exact_source: GO:0006281
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006281
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. [PMID:11563486]


systematic_name: M10862
exact_source: GO:0006283
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006283
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway. [PMID:10197977, PMID:11900249]


systematic_name: M2350
exact_source: GO:0006284
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006284
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. [ISBN:0815316194]


systematic_name: M22394
exact_source: GO:0006285
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006285
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired. [ISBN:0815316194]


systematic_name: M22395
exact_source: GO:0006287
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006287
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template. [ISBN:1550091131]


systematic_name: M12281
exact_source: GO:0006289
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006289
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts). [PMID:10197977]


systematic_name: M13298
exact_source: GO:0006297
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006297
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes. [ISBN:0815316194]


systematic_name: M14852
exact_source: GO:0006298
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006298
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. [ISBN:0198506732, PMID:11687886]


systematic_name: M11368
exact_source: GO:0006301
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006301
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication. [GOC:elh]


systematic_name: M3162
exact_source: GO:0006302
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006302
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. [GOC:elh]


systematic_name: M42630
exact_source: GO:0006303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. [GOC:rph, PMID:10827453, PMID:24837021]


systematic_name: M12430
exact_source: GO:0006304
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006304
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. [GOC:jl, GOC:ma]


systematic_name: M22398
exact_source: GO:0006307
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006307
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The repair of alkylation damage in DNA, e.g. the removal of a non-physiological alkyl group from a nucleobase. This is usually mediated by DNA alkyltransferases. [PMID:10946226, PMID:35543797]


systematic_name: M1174
exact_source: GO:0006308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. [GOC:go_curators, ISBN:0198506732]


systematic_name: M15701
exact_source: GO:0006309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520]


systematic_name: M18489
exact_source: GO:0006310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. [ISBN:0198506732]


systematic_name: M14528
exact_source: GO:0006312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles. [GOC:elh]


systematic_name: M45064
exact_source: GO:0006335
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006335
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of nucleosomes on newly synthesized DNA, coupled to strand elongation. [GOC:mah, PMID:28053344]


systematic_name: M15726
exact_source: GO:0006338
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006338
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. [GOC:jid, GOC:vw, PMID:12042764, PMID:12697820]


systematic_name: M12288
exact_source: GO:0006346
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006346
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Repression of transcription by methylation of DNA, leading to the formation of heterochromatin. [GOC:mah]


systematic_name: M13823
exact_source: GO:0006352
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006352
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. [GOC:jid, GOC:txnOH, PMID:18280161]


systematic_name: M10551
exact_source: GO:0006353
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006353
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template. [GOC:txnOH, PMID:15020047, PMID:18280161, PMID:30978344]


systematic_name: M19211
exact_source: GO:0006354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase. [GOC:mah, GOC:txnOH, PMID:15020047, PMID:18280161]


systematic_name: M22400
exact_source: GO:0006356
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006356
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I. [GOC:go_curators]


systematic_name: M22401
exact_source: GO:0006359
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006359
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III. [GOC:go_curators]


systematic_name: M22402
exact_source: GO:0006360
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006360
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter. [GOC:jl, GOC:txnOH]


systematic_name: M22403
exact_source: GO:0006361
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006361
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transcription initiation process that takes place at a RNA polymerase I gene promoter. Ribosomal RNAs (rRNA) genes are transcribed by RNA polymerase I. [GOC:txnOH]


systematic_name: M48367
exact_source: GO:0006362
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006362
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I. [GOC:mah, GOC:txnOH]


systematic_name: M5199
exact_source: GO:0006364
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006364
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. [GOC:curators]


systematic_name: M13899
exact_source: GO:0006367
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006367
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II. [GOC:mah, GOC:txnOH]


systematic_name: M14029
exact_source: GO:0006369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transcription termination process that completes the production of a primary RNA polymerase II transcript. [GOC:mah, GOC:txnOH, PMID:27371117]


systematic_name: M22406
exact_source: GO:0006382
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006382
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The conversion of an adenosine residue to inosine in an RNA molecule by deamination. [PMID:11092837]


systematic_name: M11167
exact_source: GO:0006383
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006383
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter. [GOC:jl, GOC:txnOH, PMID:12381659]


systematic_name: M22408
exact_source: GO:0006384
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006384
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III. [GOC:mah, GOC:txnOH]


systematic_name: M22409
exact_source: GO:0006390
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006390
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase. [GOC:jl, PMID:23632312]


systematic_name: M9529
exact_source: GO:0006396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. [GOC:mah]


systematic_name: M2472
exact_source: GO:0006397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. [GOC:mah]


systematic_name: M22410
exact_source: GO:0006398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine. [GOC:mah, GOC:tb, PMID:17998288]


systematic_name: M10958
exact_source: GO:0006399
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006399
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. [ISBN:0198506732]


systematic_name: M16875
exact_source: GO:0006400
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006400
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. [GOC:curators]


systematic_name: M12276
exact_source: GO:0006401
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006401
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [ISBN:0198506732]


systematic_name: M11989
exact_source: GO:0006412
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006412
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. [GOC:go_curators]


systematic_name: M11328
exact_source: GO:0006413
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006413
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. [ISBN:019879276X]


systematic_name: M14270
exact_source: GO:0006414
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006414
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. [GOC:ems]


systematic_name: M11662
exact_source: GO:0006415
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006415
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). [GOC:hjd, ISBN:019879276X]


systematic_name: M17196
exact_source: GO:0006417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:isa_complete]


systematic_name: M17238
exact_source: GO:0006446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of translational initiation. [GOC:go_curators]


systematic_name: M11322
exact_source: GO:0006448
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006448
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, extent or accuracy of translational elongation. [GOC:go_curators]


systematic_name: M22413
exact_source: GO:0006449
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006449
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of translational termination. [GOC:go_curators]


systematic_name: M15006
exact_source: GO:0006450
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006450
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the ability of the translational apparatus to interpret the genetic code. [GOC:dph, GOC:tb]


systematic_name: M22414
exact_source: GO:0006451
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006451
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons. [GOC:jsg, PMID:11179232]


systematic_name: M13856
exact_source: GO:0006457
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006457
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. [GOC:go_curators, GOC:rb]


systematic_name: M15208
exact_source: GO:0006458
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006458
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure. [GOC:mb]


systematic_name: M16386
exact_source: GO:0006465
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006465
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell. [GOC:mah, ISBN:0815316194]


systematic_name: M12694
exact_source: GO:0006473
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006473
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:ai]


systematic_name: M46728
exact_source: GO:0006476
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006476
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid. [GOC:ai]


systematic_name: M22416
exact_source: GO:0006479
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006479
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. [GOC:ai]


systematic_name: M22417
exact_source: GO:0006482
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006482
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. [GOC:mah]


systematic_name: M10780
exact_source: GO:0006487
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006487
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. [GOC:pr, RESID:AA0151, RESID:AA0156, RESID:AA0327]


systematic_name: M16610
exact_source: GO:0006490
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006490
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation. [GOC:dph, GOC:hjd, GOC:isa_complete, GOC:pr, GOC:rb]


systematic_name: M10200
exact_source: GO:0006491
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006491
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking. [ISBN:0879695595, PMID:12736198]


systematic_name: M16434
exact_source: GO:0006493
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006493
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan. [GOC:pr, ISBN:0879695595, RESID:AA0153, RESID:AA0154, RESID:AA0155, RESID:AA0157, RESID:AA0212]


systematic_name: M29034
exact_source: GO:0006505
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006505
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain. [ISBN:0198506732]


systematic_name: M17569
exact_source: GO:0006508
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006508
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah]


systematic_name: M14570
exact_source: GO:0006509
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006509
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). [GOC:jl, http://www.copewithcytokines.de/]


systematic_name: M22422
exact_source: GO:0006515
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006515
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. [GOC:jl]


systematic_name: M408
exact_source: GO:0006516
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006516
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. [GOC:go_curators, ISBN:0198506732]


systematic_name: M12056
exact_source: GO:0006518
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006518
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. [GOC:go_curators]


systematic_name: M9857
exact_source: GO:0006520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. [ISBN:0198506732]


systematic_name: M16483
exact_source: GO:0006521
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006521
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. [GOC:go_curators]


systematic_name: M29035
exact_source: GO:0006525
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006525
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. [GOC:go_curators]


systematic_name: M34066
exact_source: GO:0006526
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006526
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. [ISBN:0198506732]


systematic_name: M22424
exact_source: GO:0006527
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006527
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. [GOC:go_curators]


systematic_name: M34067
exact_source: GO:0006528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid. [GOC:go_curators]


systematic_name: M15665
exact_source: GO:0006531
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006531
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22425
exact_source: GO:0006534
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006534
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. [GOC:go_curators]


systematic_name: M10955
exact_source: GO:0006536
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006536
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. [GOC:go_curators]


systematic_name: M22427
exact_source: GO:0006538
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006538
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. [GOC:go_curators]


systematic_name: M40344
exact_source: GO:0006545
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006545
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. [GOC:go_curators]


systematic_name: M29036
exact_source: GO:0006547
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006547
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. [GOC:go_curators]


systematic_name: M34068
exact_source: GO:0006549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. [GOC:ai]


systematic_name: M22429
exact_source: GO:0006552
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006552
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of L-leucine, 2-amino-4-methylpentanoic acid. [GOC:ai]


systematic_name: M13851
exact_source: GO:0006555
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006555
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. [GOC:jl, ISBN:0198506732]


systematic_name: M29039
exact_source: GO:0006558
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006558
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid. [GOC:jsg, GOC:mah]


systematic_name: M29040
exact_source: GO:0006560
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006560
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. [GOC:jl, ISBN:0198506732]


systematic_name: M22433
exact_source: GO:0006563
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006563
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. [GOC:ai, GOC:jsg]


systematic_name: M22434
exact_source: GO:0006564
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006564
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. [GOC:ai, GOC:jsg]


systematic_name: M41800
exact_source: GO:0006565
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006565
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid. [GOC:ai, GOC:jsg]


systematic_name: M29041
exact_source: GO:0006566
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006566
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. [GOC:jl, ISBN:0198506732]


systematic_name: M45065
exact_source: GO:0006568
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006568
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. [ISBN:0198547684]


systematic_name: M22436
exact_source: GO:0006572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. [GOC:go_curators]


systematic_name: M1635
exact_source: GO:0006575
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006575
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. [GOC:ai]


systematic_name: M7597
exact_source: GO:0006576
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006576
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. [GOC:jl, ISBN:0395825172]


systematic_name: M14299
exact_source: GO:0006577
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006577
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid. [GOC:mah, ISBN:0198506732]


systematic_name: M22438
exact_source: GO:0006578
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006578
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid. [GOC:mah, ISBN:0198506732]


systematic_name: M29045
exact_source: GO:0006586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. [GOC:curators]


systematic_name: M40347
exact_source: GO:0006590
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006590
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. [GOC:jl, ISBN:0716720094]


systematic_name: M29046
exact_source: GO:0006591
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006591
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. [GOC:jl, ISBN:0192801023]


systematic_name: M12251
exact_source: GO:0006595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups. [ISBN:0198506732]


systematic_name: M22439
exact_source: GO:0006596
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006596
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. [ISBN:0198506732]


systematic_name: M29047
exact_source: GO:0006599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction. [GOC:jl, ISBN:0198506732]


systematic_name: M11119
exact_source: GO:0006605
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006605
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. [GOC:ma]


systematic_name: M14979
exact_source: GO:0006607
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006607
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope. [GOC:ai]


systematic_name: M12388
exact_source: GO:0006612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards a membrane, usually using signals contained within the protein. [GOC:curators]


systematic_name: M22441
exact_source: GO:0006613
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006613
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria. [ISBN:0716731363, PMID:10512867, PMID:16896215]


systematic_name: M42634
exact_source: GO:0006614
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006614
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane. [ISBN:0716731363]


systematic_name: M22442
exact_source: GO:0006616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen. [ISBN:0716731363]


systematic_name: M34071
exact_source: GO:0006617
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006617
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting. [ISBN:0815316194]


systematic_name: M22444
exact_source: GO:0006620
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006620
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane. [ISBN:0716731363]


systematic_name: M22445
exact_source: GO:0006621
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006621
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER. [ISBN:0716731363, PMID:12972550]


systematic_name: M16491
exact_source: GO:0006622
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006622
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards the lysosome using signals contained within the protein. [GOC:curators]


systematic_name: M22446
exact_source: GO:0006623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards the vacuole, usually using signals contained within the protein. [GOC:curators]


systematic_name: M42635
exact_source: GO:0006625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards the peroxisome, usually using signals contained within the protein. [GOC:ai]


systematic_name: M15596
exact_source: GO:0006626
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006626
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein. [GOC:mcc, ISBN:0716731363]


systematic_name: M22447
exact_source: GO:0006627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments. [GOC:mcc, PMID:12191769]


systematic_name: M14099
exact_source: GO:0006629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. [GOC:ma]


systematic_name: M17829
exact_source: GO:0006631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. [ISBN:0198547684]


systematic_name: M13591
exact_source: GO:0006633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. [GOC:mah, ISBN:0198506732]


systematic_name: M6999
exact_source: GO:0006635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). [GOC:mah, ISBN:0198506732, MetaCyc:FAO-PWY]


systematic_name: M16551
exact_source: GO:0006636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms. [GOC:mah, MetaCyc:PWY-762, MetaCyc:PWY-782]


systematic_name: M48369
exact_source: GO:0006637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group. [ISBN:0198506732]


systematic_name: M14292
exact_source: GO:0006638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity. [ISBN:0198547684]


systematic_name: M34072
exact_source: GO:0006640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. [ISBN:0198506732]


systematic_name: M22449
exact_source: GO:0006641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins. [ISBN:0198506732]


systematic_name: M15543
exact_source: GO:0006643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. [GOC:ai]


systematic_name: M10283
exact_source: GO:0006644
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006644
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732]


systematic_name: M14655
exact_source: GO:0006646
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006646
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. [ISBN:0198506732]


systematic_name: M13919
exact_source: GO:0006650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. [ISBN:0198506732]


systematic_name: M34073
exact_source: GO:0006651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. [GOC:curators]


systematic_name: M22451
exact_source: GO:0006655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. [ISBN:0198506732]


systematic_name: M10663
exact_source: GO:0006656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. [ISBN:0198506732]


systematic_name: M22452
exact_source: GO:0006657
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006657
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine. [ISBN:0471331309, MetaCyc:PWY3O-450]


systematic_name: M15367
exact_source: GO:0006658
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006658
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes. [ISBN:0198506732]


systematic_name: M46730
exact_source: GO:0006661
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006661
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. [ISBN:0198506732]


systematic_name: M22453
exact_source: GO:0006662
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006662
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol. [GOC:ai, ISBN:0198506732]


systematic_name: M12691
exact_source: GO:0006665
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006665
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). [GOC:mah, ISBN:0198506732]


systematic_name: M14627
exact_source: GO:0006672
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006672
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ceramides, any N-acylated sphingoid. [ISBN:0198547684]


systematic_name: M29049
exact_source: GO:0006677
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006677
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. [GOC:ai, ISBN:0198506732]


systematic_name: M29050
exact_source: GO:0006678
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006678
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative. [ISBN:0198506732]


systematic_name: M48370
exact_source: GO:0006680
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006680
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. [GOC:ai]


systematic_name: M48371
exact_source: GO:0006682
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006682
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. [GOC:ai]


systematic_name: M10957
exact_source: GO:0006684
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006684
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine. [ISBN:0198506732]


systematic_name: M22454
exact_source: GO:0006685
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006685
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. [ISBN:0198506732]


systematic_name: M22455
exact_source: GO:0006686
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006686
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine. [ISBN:0198506732]


systematic_name: M29051
exact_source: GO:0006687
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006687
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide. [ISBN:0198547684]


systematic_name: M13299
exact_source: GO:0006688
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006688
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide. [GOC:go_curators]


systematic_name: M22456
exact_source: GO:0006689
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006689
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues. [ISBN:0198547684]


systematic_name: M22457
exact_source: GO:0006690
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006690
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids. [GOC:ma]


systematic_name: M16416
exact_source: GO:0006691
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006691
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. [GOC:ma]


systematic_name: M15959
exact_source: GO:0006692
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006692
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure. [ISBN:0198506732]


systematic_name: M13381
exact_source: GO:0006694
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006694
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. [GOC:go_curators]


systematic_name: M12041
exact_source: GO:0006699
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006699
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. [GOC:go_curators]


systematic_name: M15204
exact_source: GO:0006700
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006700
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. [GOC:ai]


systematic_name: M22458
exact_source: GO:0006701
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006701
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. [GOC:jl, http://www.cogsci.princeton.edu/]


systematic_name: M12293
exact_source: GO:0006702
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006702
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. [ISBN:0198506732]


systematic_name: M15172
exact_source: GO:0006703
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006703
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. [ISBN:0198506732]


systematic_name: M13523
exact_source: GO:0006704
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006704
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. [ISBN:0198506732]


systematic_name: M42636
exact_source: GO:0006705
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006705
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. [ISBN:0198506732]


systematic_name: M16855
exact_source: GO:0006706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. [GOC:go_curators]


systematic_name: M22460
exact_source: GO:0006707
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006707
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. [GOC:ai]


systematic_name: M22461
exact_source: GO:0006710
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006710
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. [ISBN:0198506732]


systematic_name: M16492
exact_source: GO:0006720
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006720
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. [ISBN:0198547684]


systematic_name: M29052
exact_source: GO:0006721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. [ISBN:0198506732]


systematic_name: M13302
exact_source: GO:0006730
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006730
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. [GOC:hjd, GOC:mah, GOC:pde]


systematic_name: M13933
exact_source: GO:0006734
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006734
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid. [GOC:jl, ISBN:0618254153]


systematic_name: M10730
exact_source: GO:0006739
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006739
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. [GOC:mah]


systematic_name: M29055
exact_source: GO:0006743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme. [GOC:mah]


systematic_name: M14708
exact_source: GO:0006749
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006749
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. [ISBN:0198506732]


systematic_name: M22463
exact_source: GO:0006751
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006751
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins. [GOC:ai, ISBN:0198506732]


systematic_name: M12750
exact_source: GO:0006754
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006754
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29056
exact_source: GO:0006760
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006760
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units. [GOC:ai, GOC:mah]


systematic_name: M16119
exact_source: GO:0006766
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006766
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems. [GOC:ai]


systematic_name: M13439
exact_source: GO:0006767
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006767
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water. [GOC:jl]


systematic_name: M42638
exact_source: GO:0006771
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006771
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). [GOC:jl, http://www.indstate.edu/thcme/mwking/vitamins.html]


systematic_name: M13330
exact_source: GO:0006775
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006775
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. [GOC:jl, ISBN:0198506732]


systematic_name: M22466
exact_source: GO:0006776
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006776
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene. [GOC:jl, http://www.dentistry.leeds.ac.uk/biochem/thcme/vitamins.html#k]


systematic_name: M11983
exact_source: GO:0006778
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006778
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. [GOC:jl, ISBN:0198506732, Wikipedia:Porphyrin#Natural_formation]


systematic_name: M22467
exact_source: GO:0006782
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006782
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX. [GOC:go_curators]


systematic_name: M9906
exact_source: GO:0006790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. [GOC:ai]


systematic_name: M11249
exact_source: GO:0006801
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006801
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species. [GOC:jl]


systematic_name: M3609
exact_source: GO:0006805
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006805
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc]


systematic_name: M42639
exact_source: GO:0006811
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006811
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. [GOC:ai]


systematic_name: M11869
exact_source: GO:0006812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. [GOC:ai]


systematic_name: M10060
exact_source: GO:0006813
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006813
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M16391
exact_source: GO:0006814
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006814
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M40348
exact_source: GO:0006816
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006816
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M13372
exact_source: GO:0006817
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006817
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of phosphate ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M42640
exact_source: GO:0006820
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006820
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a monoatomic anion, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom. [GOC:ai]


systematic_name: M12615
exact_source: GO:0006821
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006821
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22471
exact_source: GO:0006824
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006824
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of cobalt (Co2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M11794
exact_source: GO:0006825
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006825
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M11591
exact_source: GO:0006826
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006826
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M46731
exact_source: GO:0006828
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006828
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22472
exact_source: GO:0006829
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006829
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M12180
exact_source: GO:0006833
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006833
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M13852
exact_source: GO:0006835
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006835
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M11274
exact_source: GO:0006836
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006836
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. [GOC:ai]


systematic_name: M22473
exact_source: GO:0006837
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006837
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. [GOC:ai]


systematic_name: M48372
exact_source: GO:0006842
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006842
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M46732
exact_source: GO:0006848
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006848
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22475
exact_source: GO:0006851
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006851
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion. [GOC:ai]


systematic_name: M11498
exact_source: GO:0006855
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006855
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:ai, GOC:bf, GOC:krc]


systematic_name: M48373
exact_source: GO:0006857
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006857
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages. [ISBN:0198506732]


systematic_name: M11774
exact_source: GO:0006862
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006862
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell. [ISBN:0198506732]


systematic_name: M13394
exact_source: GO:0006865
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006865
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M22479
exact_source: GO:0006868
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006868
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]


systematic_name: M11074
exact_source: GO:0006879
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006879
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell. [GOC:ai, GOC:mah]


systematic_name: M45811
exact_source: GO:0006882
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006882
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of zinc ions within a cell. [GOC:ai, GOC:mah]


systematic_name: M13498
exact_source: GO:0006883
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006883
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell. [GOC:ai, GOC:mah]


systematic_name: M15548
exact_source: GO:0006884
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006884
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M14452
exact_source: GO:0006885
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006885
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M10598
exact_source: GO:0006886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. [GOC:mah]


systematic_name: M1231
exact_source: GO:0006887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. [GOC:mah, ISBN:0716731363, PMID:22323285]


systematic_name: M12529
exact_source: GO:0006888
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006888
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi. [GOC:ascb_2009, GOC:dph, GOC:jp, GOC:tb, ISBN:0716731363]


systematic_name: M22482
exact_source: GO:0006890
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006890
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. [ISBN:0716731363, PMID:16510524]


systematic_name: M11795
exact_source: GO:0006891
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006891
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network). [ISBN:0716731363]


systematic_name: M19178
exact_source: GO:0006892
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006892
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. [GOC:ai, GOC:mah]


systematic_name: M12387
exact_source: GO:0006893
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006893
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. [ISBN:0716731363]


systematic_name: M13587
exact_source: GO:0006895
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006895
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes. [GOC:jl, ISBN:0716731363, PMID:10873832]


systematic_name: M16060
exact_source: GO:0006897
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006897
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. [GOC:mah, ISBN:0198506732, ISBN:0716731363, Wikipedia:Endocytosis]


systematic_name: M18488
exact_source: GO:0006898
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006898
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. [GOC:mah, ISBN:0716731363]


systematic_name: M45067
exact_source: GO:0006901
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006901
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination. [GOC:jid]


systematic_name: M11195
exact_source: GO:0006903
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006903
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. [GOC:mah, PMID:17335816]


systematic_name: M12489
exact_source: GO:0006904
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006904
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis. [GOC:aruk, GOC:bc, GOC:jid, PMID:22438915]


systematic_name: M10341
exact_source: GO:0006907
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006907
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane. [ISBN:0198506732]


systematic_name: M16307
exact_source: GO:0006909
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006909
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. [ISBN:0198506732]


systematic_name: M16726
exact_source: GO:0006910
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006910
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell. [GOC:curators, ISBN:0781735149]


systematic_name: M45812
exact_source: GO:0006911
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006911
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis. [GOC:curators, ISBN:0781735149]


systematic_name: M45068
exact_source: GO:0006915
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006915
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263]


systematic_name: M6665
exact_source: GO:0006919
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006919
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. [GOC:al, GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, PMID:18328827, Wikipedia:Caspase]


systematic_name: M18530
exact_source: GO:0006921
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006921
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M22486
exact_source: GO:0006924
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006924
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196, PMID:12414721, PMID:12752672]


systematic_name: M22487
exact_source: GO:0006925
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006925
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. [GOC:jl, GOC:mtg_apoptosis]


systematic_name: M15295
exact_source: GO:0006929
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006929
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate. [ISBN:0815316194, PMID:11944043, PMID:14657486]


systematic_name: M22488
exact_source: GO:0006930
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006930
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell. [ISBN:0815316194, PMID:11944043, PMID:14657486]


systematic_name: M12628
exact_source: GO:0006936
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006936
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. [GOC:ef, GOC:mtg_muscle, ISBN:0198506732]


systematic_name: M13593
exact_source: GO:0006939
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006939
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732]


systematic_name: M11136
exact_source: GO:0006940
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006940
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of smooth muscle contraction. [GOC:go_curators]


systematic_name: M19924
exact_source: GO:0006941
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006941
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. [GOC:jl, GOC:mtg_muscle, ISBN:0198506732]


systematic_name: M12174
exact_source: GO:0006942
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006942
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of striated muscle contraction. [GOC:go_curators]


systematic_name: M16681
exact_source: GO:0006949
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006949
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. [ISBN:0198506732]


systematic_name: M3458
exact_source: GO:0006952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. [GOC:go_curators]


systematic_name: M16862
exact_source: GO:0006953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. [ISBN:0198506732]


systematic_name: M10617
exact_source: GO:0006954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. [GO_REF:0000022, ISBN:0198506732]


systematic_name: M12406
exact_source: GO:0006956
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006956
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway. [GO_REF:0000022, GOC:add, ISBN:0781735149]


systematic_name: M13163
exact_source: GO:0006957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes. [GOC:add, ISBN:0781735149]


systematic_name: M45813
exact_source: GO:0006958
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006958
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. [GOC:add, ISBN:0781735149]


systematic_name: M16208
exact_source: GO:0006970
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006970
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. [GOC:jl]


systematic_name: M22489
exact_source: GO:0006971
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006971
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell. [GOC:jl, PMID:12598593]


systematic_name: M11354
exact_source: GO:0006972
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006972
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. [GOC:jl, PMID:12142009]


systematic_name: M13636
exact_source: GO:0006974
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006974
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. [GOC:go_curators]


systematic_name: M42642
exact_source: GO:0006977
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006977
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle. [GOC:go_curators]


systematic_name: M3223
exact_source: GO:0006979
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006979
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. [GOC:jl, PMID:12115731]


systematic_name: M22491
exact_source: GO:0006983
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006983
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB. [PMID:10390516]


systematic_name: M12546
exact_source: GO:0006984
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006984
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. [GOC:mah]


systematic_name: M22492
exact_source: GO:0006991
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006991
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [GOC:bf, ISBN:0198506732]


systematic_name: M13020
exact_source: GO:0006997
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006997
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. [GOC:dph, GOC:ems, GOC:jl, GOC:mah]


systematic_name: M15019
exact_source: GO:0006998
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006998
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. [GOC:dph, GOC:ems, GOC:jl, GOC:mah]


systematic_name: M11924
exact_source: GO:0006999
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0006999
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore. [GOC:dph, GOC:jid, GOC:jl, GOC:mah]


systematic_name: M22494
exact_source: GO:0007000
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007000
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. [GOC:dph, GOC:jid, GOC:jl, GOC:mah]


systematic_name: M3040
exact_source: GO:0007005
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007005
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. [GOC:dph, GOC:jl, GOC:mah, GOC:sgd_curators, PMID:9786946]


systematic_name: M5628
exact_source: GO:0007006
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007006
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M12841
exact_source: GO:0007007
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007007
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane. [GOC:ai, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M11086
exact_source: GO:0007009
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007009
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M6657
exact_source: GO:0007010
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007010
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M13068
exact_source: GO:0007015
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007015
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. [GOC:mah]


systematic_name: M4758
exact_source: GO:0007017
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007017
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. [GOC:mah]


systematic_name: M3616
exact_source: GO:0007018
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007018
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. [GOC:cjm, ISBN:0815316194]


systematic_name: M11488
exact_source: GO:0007020
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007020
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). [GOC:go_curators, ISBN:0815316194, PMID:12517712]


systematic_name: M22497
exact_source: GO:0007021
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007021
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer. [GOC:mah]


systematic_name: M29060
exact_source: GO:0007023
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007023
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors. [PMID:10542094]


systematic_name: M22499
exact_source: GO:0007028
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007028
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [GOC:curators, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M15310
exact_source: GO:0007029
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007029
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M16920
exact_source: GO:0007030
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007030
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M3524
exact_source: GO:0007031
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007031
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules. [GOC:mah]


systematic_name: M10494
exact_source: GO:0007032
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007032
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes. [GOC:dph, GOC:jl, GOC:mah]


systematic_name: M1054
exact_source: GO:0007033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. [GOC:mah]


systematic_name: M13305
exact_source: GO:0007035
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007035
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion. [GOC:jid]


systematic_name: M22500
exact_source: GO:0007039
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007039
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. [GOC:mah, GOC:vw]


systematic_name: M22501
exact_source: GO:0007042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion. [GOC:jid]


systematic_name: M15540
exact_source: GO:0007043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a junction between cells. [GOC:ai]


systematic_name: M9669
exact_source: GO:0007049
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007049
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. [GOC:go_curators, GOC:mtg_cell_cycle]


systematic_name: M18881
exact_source: GO:0007051
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007051
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. [GOC:go_curators, GOC:mah]


systematic_name: M2825
exact_source: GO:0007052
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007052
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. [GOC:go_curators, GOC:mah]


systematic_name: M42643
exact_source: GO:0007056
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007056
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. [GOC:mah]


systematic_name: M19628
exact_source: GO:0007059
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007059
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw]


systematic_name: M13145
exact_source: GO:0007062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other. [GOC:jh, GOC:mah, ISBN:0815316194]


systematic_name: M15695
exact_source: GO:0007063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of sister chromatid cohesion. [GOC:go_curators]


systematic_name: M16318
exact_source: GO:0007064
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007064
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission. [GOC:ai, GOC:rn, PMID:10827941, PMID:11389843, PMID:14623866]


systematic_name: M16780
exact_source: GO:0007076
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007076
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. [GOC:mah, ISBN:0815316194]


systematic_name: M22503
exact_source: GO:0007077
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007077
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis. [GOC:bf, PMID:32848252]


systematic_name: M22504
exact_source: GO:0007080
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007080
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division. [ISBN:0815316194]


systematic_name: M8627
exact_source: GO:0007093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage. [GOC:mtg_cell_cycle]


systematic_name: M13382
exact_source: GO:0007095
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007095
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. [GOC:mtg_cell_cycle, PMID:16299494]


systematic_name: M11467
exact_source: GO:0007096
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007096
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity. [GOC:rn]


systematic_name: M16642
exact_source: GO:0007129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete. [GOC:mtg_cell_cycle, PMID:22582262, PMID:23117617, PMID:31811152]


systematic_name: M22507
exact_source: GO:0007140
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007140
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. [GOC:dph, GOC:mah, GOC:vw]


systematic_name: M13719
exact_source: GO:0007141
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007141
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline. [GOC:dph, GOC:mah]


systematic_name: M22508
exact_source: GO:0007143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. [GOC:dph, GOC:ems, GOC:mah, GOC:vw]


systematic_name: M45069
exact_source: GO:0007155
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007155
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf]


systematic_name: M7823
exact_source: GO:0007156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell. [ISBN:0198506732]


systematic_name: M10391
exact_source: GO:0007157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell. [ISBN:0198506732]


systematic_name: M17747
exact_source: GO:0007162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. [GOC:go_curators]


systematic_name: M1049
exact_source: GO:0007163
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007163
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. [GOC:mah]


systematic_name: M34077
exact_source: GO:0007164
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007164
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates. [GOC:jid]


systematic_name: M284
exact_source: GO:0007167
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007167
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, ISBN:0815316194]


systematic_name: M22510
exact_source: GO:0007168
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007168
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:16815030]


systematic_name: M17660
exact_source: GO:0007169
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007169
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:ceb, GOC:signaling]


systematic_name: M16019
exact_source: GO:0007171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. [GOC:dph, GOC:tb]


systematic_name: M22511
exact_source: GO:0007172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. [GOC:bf, GOC:signaling, PMID:9646862]


systematic_name: M10399
exact_source: GO:0007173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. [GOC:ceb]


systematic_name: M22512
exact_source: GO:0007175
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007175
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity. [GOC:go_curators]


systematic_name: M11285
exact_source: GO:0007176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of EGF-activated receptor activity. [GOC:dph, GOC:go_curators]


systematic_name: M7385
exact_source: GO:0007178
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007178
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]


systematic_name: M15660
exact_source: GO:0007179
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007179
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:BHF, GOC:mah, GOC:signaling]


systematic_name: M22515
exact_source: GO:0007185
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007185
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]


systematic_name: M2280
exact_source: GO:0007186
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007186
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


systematic_name: M6402
exact_source: GO:0007187
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007187
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide. [GOC:mah, GOC:signaling, ISBN:0815316194]


systematic_name: M12190
exact_source: GO:0007188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP). [GOC:mah, GOC:signaling, ISBN:0815316194]


systematic_name: M1768
exact_source: GO:0007189
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007189
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194]


systematic_name: M14081
exact_source: GO:0007191
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007191
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:mah, GOC:signaling]


systematic_name: M14835
exact_source: GO:0007193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP). [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194]


systematic_name: M22517
exact_source: GO:0007195
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007195
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


systematic_name: M22518
exact_source: GO:0007196
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007196
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


systematic_name: M22519
exact_source: GO:0007197
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007197
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


systematic_name: M29061
exact_source: GO:0007198
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007198
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by serotonin binding to its receptor, and ending with the regulation of a downstream cellular process. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


systematic_name: M15400
exact_source: GO:0007200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). [GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194]


systematic_name: M419
exact_source: GO:0007202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand. [GOC:dph, GOC:mah, GOC:tb, PMID:8280098]


systematic_name: M12634
exact_source: GO:0007205
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007205
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG). [GOC:mah, GOC:signaling]


systematic_name: M45814
exact_source: GO:0007207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:dph, GOC:mah, GOC:signaling, GOC:tb]


systematic_name: M22520
exact_source: GO:0007210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. [GOC:mah]


systematic_name: M16457
exact_source: GO:0007212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands. [GOC:mah, PMID:21711983]


systematic_name: M22521
exact_source: GO:0007213
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007213
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription. [GOC:mah, ISBN:0815316194]


systematic_name: M11337
exact_source: GO:0007214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell. [GOC:mah]


systematic_name: M17444
exact_source: GO:0007215
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007215
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling, PMID:9131252]


systematic_name: M11464
exact_source: GO:0007216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:mah, GOC:signaling, PMID:9131252]


systematic_name: M22522
exact_source: GO:0007217
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007217
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by tachykinin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. Tachykinin is a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2). [GOC:mah, PMID:14723970]


systematic_name: M7277
exact_source: GO:0007218
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007218
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:mah, ISBN:0815316194]


systematic_name: M3744
exact_source: GO:0007219
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007219
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to the receptor Notch on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:go_curators, GOC:signaling]


systematic_name: M10979
exact_source: GO:0007220
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007220
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor. [PMID:12651094, PMID:14986688]


systematic_name: M22523
exact_source: GO:0007221
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007221
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain. [PMID:12651094]


systematic_name: M11621
exact_source: GO:0007223
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007223
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A type of non-canonical Wnt signaling in which Wnt binding to its receptor on the surface of a target cell leads to an increase in intracellular calcium and activation of protein kinase C (PKC). [PMID:11532397, PMID:37804416]


systematic_name: M14890
exact_source: GO:0007224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. [GOC:mah, PMID:15057936, PMID:15205520]


systematic_name: M15881
exact_source: GO:0007229
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007229
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to an integrin on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:mah, GOC:signaling]


systematic_name: M10984
exact_source: GO:0007249
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007249
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette characterized by the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB, also known as the canonical NF-kappaB signaling cascade. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. The canonical NF-kappaB pathway is mainly stimulated by proinflammatory cytokines such as IL-1beta, tumor necrosis factor (TNF)-alpha, antigen ligands, and toll-like receptors (TLRs). [GOC:bf, PMID:12773372, PMID:34659217]


systematic_name: M11081
exact_source: GO:0007250
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007250
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues. [GOC:jl, PMID:12773372]


systematic_name: M14423
exact_source: GO:0007252
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007252
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription. [GOC:bf, GOC:jl, PMID:21772278, PMID:7594468]


systematic_name: M22524
exact_source: GO:0007253
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007253
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. [GOC:jl]


systematic_name: M13069
exact_source: GO:0007254
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007254
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A MAPK cascade containing at least the JNK (MAPK8) MAP kinase. It starts with the activation of JUN3K (a MAPK3K), which activates JNKK a MAP2K), which in turn activates JNK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The JNK cascade is activated by stress signals, as well as by G protein-coupled receptors, growth factors, and cytokines, and results in cellular responses such as cell proliferation, cell differentiation, apoptosis and inflammation. [PMID:11790549, PMID:20811974, PMID:23125017]


systematic_name: M5562
exact_source: GO:0007260
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007260
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein. [GOC:jl, PMID:10918594]


systematic_name: M15820
exact_source: GO:0007263
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007263
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette that starts with production of nitric oxide, detection by receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and ends with the activation of downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms. [GOC:jl, PMID:21549190]


systematic_name: M13487
exact_source: GO:0007265
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007265
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Ras subfamily relays a signal. [GOC:bf]


systematic_name: M7069
exact_source: GO:0007266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  An intracellular signaling cassette in which a small monomeric GTPase of the Rho subfamily relays a signal. [GOC:bf]


systematic_name: M11874
exact_source: GO:0007267
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007267
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. [GOC:dos, GOC:mah]


systematic_name: M29062
exact_source: GO:0007269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. [GOC:dph]


systematic_name: M12840
exact_source: GO:0007270
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007270
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of synaptic transmission from a neuron to another neuron across a synapse. [GOC:add, GOC:dos, GOC:jl, MeSH:D009435]


systematic_name: M11082
exact_source: GO:0007271
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007271
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. [GOC:dos, Wikipedia:Cholinergic]


systematic_name: M12937
exact_source: GO:0007272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. [GOC:dgh, GOC:dph, GOC:tb]


systematic_name: M15769
exact_source: GO:0007274
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007274
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of synaptic transmission from a neuron to a muscle, across a synapse. [GOC:dos, GOC:jl, MeSH:D009435]


systematic_name: M45815
exact_source: GO:0007276
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007276
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. [GOC:ems, GOC:mtg_sensu]


systematic_name: M45072
exact_source: GO:0007288
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007288
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. [GOC:bf, GOC:cilia, ISBN:0198547684]


systematic_name: M13895
exact_source: GO:0007289
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007289
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. [GOC:bf, GOC:dph, GOC:jl, GOC:mah]


systematic_name: M14814
exact_source: GO:0007292
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007292
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. [GOC:dph, ISBN:0198506732]


systematic_name: M46734
exact_source: GO:0007308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732]


systematic_name: M48374
exact_source: GO:0007314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238]


systematic_name: M16221
exact_source: GO:0007339
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007339
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place. [GOC:dph, ISBN:0878932437]


systematic_name: M14797
exact_source: GO:0007340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida. [GOC:dph, PMID:11175768, PMID:21042299, PMID:3886029]


systematic_name: M22527
exact_source: GO:0007341
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007341
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm. [GOC:jl, http://arbl.cvmbs.colostate.edu/hbooks/pathphys/reprod/fert/fert.html]


systematic_name: M22529
exact_source: GO:0007343
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007343
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. [GOC:bf, PMID:9630751]


systematic_name: M19030
exact_source: GO:0007346
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007346
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or extent of progress through the mitotic cell cycle. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M14056
exact_source: GO:0007350
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007350
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M14898
exact_source: GO:0007351
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007351
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M42645
exact_source: GO:0007354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M22531
exact_source: GO:0007356
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007356
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M13572
exact_source: GO:0007369
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007369
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. [GOC:curators, ISBN:9780878933846]


systematic_name: M14196
exact_source: GO:0007379
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007379
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M42646
exact_source: GO:0007386
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007386
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation. [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238]


systematic_name: M5927
exact_source: GO:0007389
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007389
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. [GOC:go_curators, GOC:isa_complete, ISBN:0521436125]


systematic_name: M12267
exact_source: GO:0007398
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007398
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. [GOC:dph, GOC:tb]


systematic_name: M16110
exact_source: GO:0007405
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007405
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. [GOC:ai, GOC:mtg_sensu, GOC:sart]


systematic_name: M22533
exact_source: GO:0007406
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007406
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. [GOC:ai]


systematic_name: M10639
exact_source: GO:0007416
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007416
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). [GOC:mah]


systematic_name: M974
exact_source: GO:0007417
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007417
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. [GOC:bf, GOC:jid, ISBN:0582227089]


systematic_name: M42647
exact_source: GO:0007418
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007418
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. [GOC:bf, GOC:go_curators, PMID:12075342]


systematic_name: M15524
exact_source: GO:0007422
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007422
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. [GOC:go_curators, UBERON:0000010]


systematic_name: M15223
exact_source: GO:0007423
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007423
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. [GOC:go_curators]


systematic_name: M10696
exact_source: GO:0007431
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007431
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. [GOC:jid, UBERON:0001044]


systematic_name: M22534
exact_source: GO:0007440
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007440
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the foregut are generated and organized. [GOC:jid]


systematic_name: M13755
exact_source: GO:0007492
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007492
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. [GOC:dph, GOC:tb]


systematic_name: M16113
exact_source: GO:0007494
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007494
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. [GOC:jid, UBERON:0001045]


systematic_name: M15421
exact_source: GO:0007498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. [GOC:dph, GOC:tb]


systematic_name: M22535
exact_source: GO:0007501
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007501
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:go_curators]


systematic_name: M22536
exact_source: GO:0007506
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007506
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. [GOC:ai]


systematic_name: M8348
exact_source: GO:0007507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:jid, UBERON:0000948]


systematic_name: M15404
exact_source: GO:0007512
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007512
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure. [GOC:bf]


systematic_name: M774
exact_source: GO:0007517
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007517
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. [GOC:jid, ISBN:0198506732]


systematic_name: M16873
exact_source: GO:0007520
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007520
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. [CL:0000056, GOC:mtg_muscle]


systematic_name: M10077
exact_source: GO:0007528
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007528
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. [GOC:mtg_OBO2OWL_2013]


systematic_name: M11201
exact_source: GO:0007530
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007530
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that establishes and transmits the specification of sexual status of an individual organism. [ISBN:0198506732]


systematic_name: M22537
exact_source: GO:0007549
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007549
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes. [GOC:ems, PMID:11498577, PMID:30049999, PMID:35306885]


systematic_name: M13603
exact_source: GO:0007567
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007567
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs. [ISBN:0198506732]


systematic_name: M15950
exact_source: GO:0007584
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007584
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. [GOC:go_curators]


systematic_name: M10354
exact_source: GO:0007585
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007585
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. [ISBN:0198506732]


systematic_name: M10163
exact_source: GO:0007586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [GOC:isa_complete, ISBN:0198506732]


systematic_name: M10162
exact_source: GO:0007588
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007588
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. [ISBN:0192801023]


systematic_name: M14825
exact_source: GO:0007589
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007589
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The controlled release of a fluid by a cell or tissue in an animal. [GOC:ai, GOC:dph, GOC:mah, GOC:tb]


systematic_name: M16885
exact_source: GO:0007595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. [ISBN:0198506732]


systematic_name: M13351
exact_source: GO:0007597
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007597
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X. [GOC:add, GOC:mah, GOC:pde]


systematic_name: M14945
exact_source: GO:0007599
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007599
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. [ISBN:0198506732]


systematic_name: M14699
exact_source: GO:0007600
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007600
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai, GOC:dph]


systematic_name: M11253
exact_source: GO:0007602
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007602
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. [GOC:go_curators]


systematic_name: M12905
exact_source: GO:0007603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. [GOC:go_curators, ISBN:0198506732]


systematic_name: M11231
exact_source: GO:0007606
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007606
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. [GOC:ai]


systematic_name: M22538
exact_source: GO:0007608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. [GOC:ai]


systematic_name: M10444
exact_source: GO:0007610
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007610
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973]


systematic_name: M13048
exact_source: GO:0007612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. [ISBN:0582227089, ISBN:0721662544]


systematic_name: M10099
exact_source: GO:0007613
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007613
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). [GOC:curators, ISBN:0582227089]


systematic_name: M22539
exact_source: GO:0007614
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007614
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation. [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089]


systematic_name: M13777
exact_source: GO:0007616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation. [http://hebb.mit.edu/courses/9.03/lecture4.html, ISBN:0582227089]


systematic_name: M46736
exact_source: GO:0007617
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007617
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. [GOC:ai, GOC:dph]


systematic_name: M10045
exact_source: GO:0007623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any biological process in an organism that recurs with a regularity of approximately 24 hours. [GOC:bf, GOC:go_curators]


systematic_name: M14426
exact_source: GO:0007625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites. [GOC:jl, GOC:pr]


systematic_name: M7204
exact_source: GO:0007626
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0007626
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. [GOC:dph]


systematic_name: M40351
exact_source: GO:0008016
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008016
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M16373
exact_source: GO:0008033
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008033
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. [GOC:jl, PMID:12533506]


systematic_name: M10326
exact_source: GO:0008038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a neuronal cell in a multicellular organism interprets its surroundings. [GOC:go_curators]


systematic_name: M12159
exact_source: GO:0008045
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008045
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. [CL:0000100, GOC:pr, ISBN:0878932437]


systematic_name: M14442
exact_source: GO:0008053
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008053
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Merging of two or more mitochondria within a cell to form a single compartment. [PMID:11038192, PMID:12052774]


systematic_name: M22540
exact_source: GO:0008063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals initiated by an extracellular ligand binding to the receptor Toll on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. [GOC:go_curators, PMID:11135568, PMID:19126860]


systematic_name: M45073
exact_source: GO:0008078
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008078
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of mesodermal cells from one site to another. [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047]


systematic_name: M10408
exact_source: GO:0008088
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008088
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organelles or molecules along microtubules in neuron projections. [ISBN:0815316194]


systematic_name: M29064
exact_source: GO:0008089
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008089
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. [ISBN:0815316194]


systematic_name: M22542
exact_source: GO:0008090
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008090
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons. [ISBN:0815316194]


systematic_name: M2403
exact_source: GO:0008154
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008154
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. [GOC:mah]


systematic_name: M17293
exact_source: GO:0008156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication. [GOC:go_curators]


systematic_name: M16758
exact_source: GO:0008202
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008202
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. [ISBN:0198547684]


systematic_name: M17975
exact_source: GO:0008206
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008206
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. [GOC:go_curators]


systematic_name: M11034
exact_source: GO:0008207
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008207
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. [GOC:ai]


systematic_name: M13960
exact_source: GO:0008209
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008209
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. [ISBN:0198506732]


systematic_name: M16636
exact_source: GO:0008210
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008210
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. [ISBN:0198506732]


systematic_name: M10776
exact_source: GO:0008211
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008211
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. [ISBN:0198506732]


systematic_name: M29066
exact_source: GO:0008212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. [ISBN:0198506732]


systematic_name: M29067
exact_source: GO:0008215
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008215
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. [GOC:curators]


systematic_name: M22543
exact_source: GO:0008216
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008216
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane. [GOC:ai]


systematic_name: M10469
exact_source: GO:0008217
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008217
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. [GOC:dph, GOC:mtg_cardio, ISBN:0721643949]


systematic_name: M22544
exact_source: GO:0008228
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008228
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody. [GOC:add, GOC:mah, ISBN:0198506732, ISBN:068340007X, ISBN:0781735149]


systematic_name: M11256
exact_source: GO:0008272
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008272
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:krc]


systematic_name: M22545
exact_source: GO:0008277
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008277
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. [GOC:go_curators]


systematic_name: M6566
exact_source: GO:0008285
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008285
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators]


systematic_name: M18583
exact_source: GO:0008286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. [GOC:ceb]


systematic_name: M22548
exact_source: GO:0008298
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008298
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which mRNA is transported to, or maintained in, a specific location within the cell. [GOC:ai]


systematic_name: M15231
exact_source: GO:0008299
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008299
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. [ISBN:0198506732]


systematic_name: M22549
exact_source: GO:0008300
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008300
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. [ISBN:0198506732]


systematic_name: M10883
exact_source: GO:0008306
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008306
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Learning by associating a stimulus (the cause) with a particular outcome (the effect). [ISBN:0582227089]


systematic_name: M42648
exact_source: GO:0008315
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008315
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I. [PMID:15084480]


systematic_name: M14732
exact_source: GO:0008334
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008334
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving an mRNA encoding a histone. [GOC:krc, GOC:mah, PMID:17855393]


systematic_name: M14847
exact_source: GO:0008340
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008340
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The pathways that regulate the duration of the adult phase of the life-cycle of an animal. [PMID:25561524, PMID:273723695, PMID:3424805]


systematic_name: M14116
exact_source: GO:0008347
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008347
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. [GOC:jl, GOC:mtg_sensu]


systematic_name: M22551
exact_source: GO:0008354
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008354
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. [GOC:bf, GOC:jl]


systematic_name: M12036
exact_source: GO:0008356
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008356
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. [PMID:11672519]


systematic_name: M13559
exact_source: GO:0008380
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008380
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. [GOC:krc, GOC:mah]


systematic_name: M10577
exact_source: GO:0008535
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008535
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms. [GOC:jl, http://www.med.wright.edu/bmb/lp/lplab.htm]


systematic_name: M14806
exact_source: GO:0008543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. [GOC:ceb]


systematic_name: M14065
exact_source: GO:0008544
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008544
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. [GOC:go_curators, UBERON:0001003]


systematic_name: M45816
exact_source: GO:0008582
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008582
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions. [GOC:go_curators]


systematic_name: M48375
exact_source: GO:0008592
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008592
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the Tl signaling pathway. [GOC:go_curators]


systematic_name: M14001
exact_source: GO:0008593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the Notch signaling pathway. [GOC:go_curators]


systematic_name: M45074
exact_source: GO:0008594
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008594
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. [GOC:jid, GOC:mah]


systematic_name: M10211
exact_source: GO:0008608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex. [GOC:vw, PMID:10322137]


systematic_name: M14504
exact_source: GO:0008610
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008610
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. [GOC:go_curators]


systematic_name: M13726
exact_source: GO:0008625
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008625
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered. [GOC:mah, GOC:mtg_apoptosis]


systematic_name: M22554
exact_source: GO:0008627
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008627
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered. [GOC:mtg_apoptosis, PMID:11454444, PMID:16483738]


systematic_name: M48376
exact_source: GO:0008628
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008628
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered. [GOC:bf, GOC:mtg_apoptosis]


systematic_name: M13458
exact_source: GO:0008630
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008630
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. [GOC:go_curators, GOC:mtg_apoptosis]


systematic_name: M22556
exact_source: GO:0008631
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008631
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. [GOC:ai, GOC:mtg_apoptosis]


systematic_name: M22557
exact_source: GO:0008635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c. [GOC:dph, GOC:jl, GOC:mtg_apoptosis, GOC:tb, PMID:14744432, Wikipedia:Caspase]


systematic_name: M7482
exact_source: GO:0008637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The morphological and physiological alterations undergone by mitochondria during apoptosis. [GOC:mah, GOC:mtg_apoptosis]


systematic_name: M10256
exact_source: GO:0008643
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008643
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. [GOC:ai]


systematic_name: M11377
exact_source: GO:0008652
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008652
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. [ISBN:0198506732]


systematic_name: M11978
exact_source: GO:0008654
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008654
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732]


systematic_name: M13567
exact_source: GO:0008655
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0008655
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis. [GOC:jl]


systematic_name: M22558
exact_source: GO:0009052
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009052
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P. [ISBN:0198506732, MetaCyc:NONOXIPENT-PWY]


systematic_name: M1112
exact_source: GO:0009057
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009057
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. [GOC:mah]


systematic_name: M11785
exact_source: GO:0009060
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009060
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. [GOC:das, GOC:jl, ISBN:0140513590]


systematic_name: M10250
exact_source: GO:0009062
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009062
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. [GOC:go_curators]


systematic_name: M15063
exact_source: GO:0009063
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009063
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. [GOC:ai]


systematic_name: M11431
exact_source: GO:0009064
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009064
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. [GOC:ai]


systematic_name: M10807
exact_source: GO:0009065
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009065
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. [GOC:ai]


systematic_name: M15039
exact_source: GO:0009066
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009066
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. [GOC:ai]


systematic_name: M11470
exact_source: GO:0009067
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009067
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. [GOC:ai]


systematic_name: M13099
exact_source: GO:0009068
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009068
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. [GOC:ai]


systematic_name: M16092
exact_source: GO:0009069
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009069
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. [GOC:ai]


systematic_name: M11026
exact_source: GO:0009070
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009070
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. [GOC:ai]


systematic_name: M22559
exact_source: GO:0009071
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009071
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. [GOC:ai]


systematic_name: M12883
exact_source: GO:0009072
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009072
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). [GOC:go_curators]


systematic_name: M15416
exact_source: GO:0009074
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009074
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). [GOC:go_curators]


systematic_name: M45817
exact_source: GO:0009078
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009078
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine. [GOC:jl]


systematic_name: M48377
exact_source: GO:0009080
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009080
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine. [GOC:jl]


systematic_name: M29069
exact_source: GO:0009081
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009081
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. [GOC:ai]


systematic_name: M34078
exact_source: GO:0009082
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009082
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. [GOC:ai]


systematic_name: M42650
exact_source: GO:0009083
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009083
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine. [GOC:ai]


systematic_name: M10295
exact_source: GO:0009084
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009084
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. [GOC:ai]


systematic_name: M13431
exact_source: GO:0009086
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009086
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. [GOC:jl, ISBN:0198506732]


systematic_name: M45075
exact_source: GO:0009092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine. [GOC:go_curators, ISBN:0198506732]


systematic_name: M48378
exact_source: GO:0009093
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009093
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid. [GOC:go_curators]


systematic_name: M16741
exact_source: GO:0009100
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009100
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22563
exact_source: GO:0009101
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009101
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. [GOC:go_curators, ISBN:0198506732]


systematic_name: M13391
exact_source: GO:0009110
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009110
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22564
exact_source: GO:0009111
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009111
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. [GOC:ai]


systematic_name: M12754
exact_source: GO:0009112
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009112
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. [GOC:ma]


systematic_name: M13379
exact_source: GO:0009113
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009113
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. [ISBN:0198506732]


systematic_name: M22565
exact_source: GO:0009116
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009116
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine). [GOC:ma]


systematic_name: M29070
exact_source: GO:0009119
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009119
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. [GOC:jl]


systematic_name: M29071
exact_source: GO:0009120
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009120
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside). [GOC:jl, ISBN:0140512713]


systematic_name: M15105
exact_source: GO:0009123
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009123
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M14180
exact_source: GO:0009124
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009124
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22566
exact_source: GO:0009125
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009125
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22567
exact_source: GO:0009126
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009126
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M15156
exact_source: GO:0009127
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009127
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40353
exact_source: GO:0009128
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009128
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29072
exact_source: GO:0009129
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009129
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40354
exact_source: GO:0009130
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009130
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40355
exact_source: GO:0009131
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009131
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M10329
exact_source: GO:0009132
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009132
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22569
exact_source: GO:0009133
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009133
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22570
exact_source: GO:0009134
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009134
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40356
exact_source: GO:0009136
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009136
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40358
exact_source: GO:0009138
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009138
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42651
exact_source: GO:0009139
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009139
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M13168
exact_source: GO:0009141
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009141
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M13233
exact_source: GO:0009142
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009142
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M15102
exact_source: GO:0009143
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009143
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22573
exact_source: GO:0009146
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009146
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29074
exact_source: GO:0009147
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009147
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M11210
exact_source: GO:0009148
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009148
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29075
exact_source: GO:0009151
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009151
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M34079
exact_source: GO:0009153
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009153
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22574
exact_source: GO:0009155
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009155
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22575
exact_source: GO:0009156
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009156
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22576
exact_source: GO:0009157
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009157
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40359
exact_source: GO:0009158
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009158
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40360
exact_source: GO:0009159
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009159
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29076
exact_source: GO:0009161
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009161
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29077
exact_source: GO:0009162
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009162
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40362
exact_source: GO:0009170
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009170
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42652
exact_source: GO:0009172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29078
exact_source: GO:0009173
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009173
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M45076
exact_source: GO:0009174
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009174
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29079
exact_source: GO:0009176
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009176
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29080
exact_source: GO:0009186
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009186
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M11397
exact_source: GO:0009187
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009187
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. [GOC:go_curators, ISBN:0198506732]


systematic_name: M34080
exact_source: GO:0009188
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009188
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M14261
exact_source: GO:0009190
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009190
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42655
exact_source: GO:0009193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29082
exact_source: GO:0009200
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009200
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29083
exact_source: GO:0009208
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009208
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40364
exact_source: GO:0009209
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009209
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29084
exact_source: GO:0009211
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009211
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M11711
exact_source: GO:0009214
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009214
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29085
exact_source: GO:0009215
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009215
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29086
exact_source: GO:0009218
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009218
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M29087
exact_source: GO:0009219
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009219
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40365
exact_source: GO:0009220
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009220
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M22584
exact_source: GO:0009221
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009221
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M40366
exact_source: GO:0009222
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009222
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M17914
exact_source: GO:0009225
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009225
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. [ISBN:0198506732]


systematic_name: M16127
exact_source: GO:0009226
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009226
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. [ISBN:0198506732]


systematic_name: M12625
exact_source: GO:0009235
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009235
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. [GOC:go_curators]


systematic_name: M22585
exact_source: GO:0009240
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009240
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids. [GOC:jl, ISBN:0198506732]


systematic_name: M10674
exact_source: GO:0009247
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009247
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). [GOC:go_curators]


systematic_name: M40367
exact_source: GO:0009250
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009250
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. [GOC:go_curators]


systematic_name: M29088
exact_source: GO:0009256
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009256
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate. [GOC:ai]


systematic_name: M45077
exact_source: GO:0009262
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009262
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M14364
exact_source: GO:0009263
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009263
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M45078
exact_source: GO:0009264
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009264
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. [GOC:go_curators, ISBN:0198506732]


systematic_name: M7660
exact_source: GO:0009266
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009266
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. [GOC:hb]


systematic_name: M14501
exact_source: GO:0009267
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009267
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. [GOC:jl]


systematic_name: M14244
exact_source: GO:0009268
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009268
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. [GOC:jl, Wikipedia:PH]


systematic_name: M11730
exact_source: GO:0009303
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009303
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. [GOC:jl, ISBN:0198506732]


systematic_name: M7216
exact_source: GO:0009308
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009308
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. [GOC:jl, ISBN:0198506732]


systematic_name: M3353
exact_source: GO:0009309
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009309
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. [GOC:jl, ISBN:0198506732]


systematic_name: M7838
exact_source: GO:0009310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. [GOC:jl, ISBN:0198506732]


systematic_name: M10171
exact_source: GO:0009311
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009311
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. [ISBN:0198506732]


systematic_name: M14475
exact_source: GO:0009312
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009312
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. [ISBN:0198506732]


systematic_name: M11203
exact_source: GO:0009313
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009313
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages. [ISBN:0198506732]


systematic_name: M13646
exact_source: GO:0009314
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009314
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. [GOC:jl, Wikipedia:Electromagnetic_radiation]


systematic_name: M15731
exact_source: GO:0009395
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009395
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732]


systematic_name: M12451
exact_source: GO:0009396
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009396
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of folic acid and its derivatives. [GOC:ai]


systematic_name: M48379
exact_source: GO:0009397
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009397
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives. [GOC:ai]


systematic_name: M13243
exact_source: GO:0009404
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009404
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. [GOC:cab2]


systematic_name: M17735
exact_source: GO:0009408
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009408
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. [GOC:lr]


systematic_name: M10527
exact_source: GO:0009409
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009409
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. [GOC:lr]


systematic_name: M9008
exact_source: GO:0009410
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009410
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:jl, GOC:krc]


systematic_name: M13573
exact_source: GO:0009411
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009411
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. [GOC:hb]


systematic_name: M16777
exact_source: GO:0009414
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009414
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. [GOC:lr]


systematic_name: M16350
exact_source: GO:0009415
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009415
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. [GOC:jl]


systematic_name: M16292
exact_source: GO:0009416
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009416
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. [GOC:go_curators, ISBN:0582227089]


systematic_name: M29090
exact_source: GO:0009437
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009437
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane. [GOC:jl, ISBN:0198506732]


systematic_name: M29091
exact_source: GO:0009438
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009438
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. [GOC:ai]


systematic_name: M29092
exact_source: GO:0009445
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009445
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine. [GOC:ai]


systematic_name: M22592
exact_source: GO:0009446
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009446
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine. [GOC:go_curators, ISBN:0198506732]


systematic_name: M42657
exact_source: GO:0009448
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009448
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. [ISBN:0198506732]


systematic_name: M45079
exact_source: GO:0009449
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009449
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. [GOC:ai]


systematic_name: M12563
exact_source: GO:0009451
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009451
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically. [GOC:go_curators, ISBN:1555811337]


systematic_name: M45080
exact_source: GO:0009452
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009452
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The sequence of enzymatic reactions by which the RNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively. [GOC:vw, PMID:9266685]


systematic_name: M15335
exact_source: GO:0009566
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009566
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). [GOC:tb, ISBN:0198506732]


systematic_name: M14474
exact_source: GO:0009582
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009582
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. [GOC:hb]


systematic_name: M14135
exact_source: GO:0009583
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009583
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. [GOC:go_curators]


systematic_name: M42658
exact_source: GO:0009584
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009584
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. [GOC:go_curators, ISBN:0198506732]


systematic_name: M18259
exact_source: GO:0009595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal. [GOC:hb]


systematic_name: M22593
exact_source: GO:0009597
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009597
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The series of events in which a stimulus from a virus is received and converted into a molecular signal. [GOC:hb]


systematic_name: M34083
exact_source: GO:0009608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction. [GOC:hb, ISBN:0198506732]


systematic_name: M5634
exact_source: GO:0009611
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009611
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. [GOC:go_curators]


systematic_name: M16378
exact_source: GO:0009612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. [GOC:hb]


systematic_name: M16779
exact_source: GO:0009615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:hb]


systematic_name: M18818
exact_source: GO:0009617
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009617
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. [GOC:hb]


systematic_name: M15573
exact_source: GO:0009620
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009620
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. [GOC:hb]


systematic_name: M45082
exact_source: GO:0009624
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009624
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode. [GOC:hb]


systematic_name: M14159
exact_source: GO:0009628
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009628
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. [GOC:hb]


systematic_name: M11582
exact_source: GO:0009629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. [GOC:hb]


systematic_name: M15317
exact_source: GO:0009636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. [GOC:lr]


systematic_name: M40369
exact_source: GO:0009637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. [GOC:ai, GOC:mtg_far_red]


systematic_name: M22595
exact_source: GO:0009642
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009642
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. [GOC:go_curators]


systematic_name: M10689
exact_source: GO:0009648
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009648
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species. [GOC:jid, GOC:pj, ISBN:0582015952, ISBN:0697037754, ISBN:0709408862]


systematic_name: M11655
exact_source: GO:0009650
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009650
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV. [GOC:jl, GOC:ml]


systematic_name: M13071
exact_source: GO:0009651
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009651
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. [GOC:jl]


systematic_name: M40370
exact_source: GO:0009712
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009712
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. [GOC:sm, ISBN:0198547684]


systematic_name: M40371
exact_source: GO:0009713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. [GOC:go_curators]


systematic_name: M6658
exact_source: GO:0009719
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009719
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. [GOC:sm]


systematic_name: M13987
exact_source: GO:0009725
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009725
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. [GOC:jl]


systematic_name: M9582
exact_source: GO:0009743
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009743
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. [GOC:jl]


systematic_name: M22597
exact_source: GO:0009750
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009750
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus. [GOC:jl]


systematic_name: M15134
exact_source: GO:0009790
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009790
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu]


systematic_name: M16529
exact_source: GO:0009791
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009791
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. [GOC:go_curators]


systematic_name: M10259
exact_source: GO:0009792
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009792
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu]


systematic_name: M10396
exact_source: GO:0009798
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009798
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment, maintenance and elaboration of a pattern along a line or around a point. [GOC:dph, GOC:go_curators, GOC:isa_complete]


systematic_name: M12038
exact_source: GO:0009799
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009799
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created. [GOC:go_curators]


systematic_name: M15331
exact_source: GO:0009812
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009812
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins. [GOC:tair_curators, ISBN:0198547684]


systematic_name: M16310
exact_source: GO:0009820
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009820
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). [GOC:lr, ISBN:0122146743]


systematic_name: M13032
exact_source: GO:0009880
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009880
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that results in the patterns of cell differentiation that will arise in an embryo. [GOC:go_curators, ISBN:0521436125]


systematic_name: M22600
exact_source: GO:0009886
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009886
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. [GOC:go_curators]


systematic_name: M12326
exact_source: GO:0009887
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009887
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544]


systematic_name: M12729
exact_source: GO:0009894
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009894
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. [GOC:go_curators]


systematic_name: M16760
exact_source: GO:0009895
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009895
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. [GOC:go_curators]


systematic_name: M12781
exact_source: GO:0009896
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009896
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. [GOC:go_curators]


systematic_name: M12194
exact_source: GO:0009913
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009913
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb]


systematic_name: M11292
exact_source: GO:0009914
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009914
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:tb]


systematic_name: M14941
exact_source: GO:0009948
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009948
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M15618
exact_source: GO:0009950
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009950
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. [GOC:dph, GOC:go_curators, GOC:tb]


systematic_name: M12766
exact_source: GO:0009952
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009952
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]


systematic_name: M11780
exact_source: GO:0009953
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009953
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb]


systematic_name: M12263
exact_source: GO:0009954
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009954
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end). [GOC:dph, GOC:go_curators, GOC:isa_complete]


systematic_name: M46738
exact_source: GO:0009957
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009957
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. [GOC:mtg_sensu, GOC:sm]


systematic_name: M15483
exact_source: GO:0009988
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009988
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Cell recognition between cells. May involve the formation of specialized cell junctions. [ISBN:0824072820]


systematic_name: M34085
exact_source: GO:0009992
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009992
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A homeostatic process involved in the maintenance of a steady state level of water within a cell. [GOC:dph, GOC:tb]


systematic_name: M13948
exact_source: GO:0009994
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0009994
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. [GOC:go_curators, GOC:mtg_sensu]


systematic_name: M15366
exact_source: GO:0010001
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010001
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. [GOC:go_curators, GOC:mtg_sensu]


systematic_name: M13412
exact_source: GO:0010002
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010002
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. [GOC:go_curators]


systematic_name: M11882
exact_source: GO:0010035
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010035
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. [GOC:sm]


systematic_name: M11938
exact_source: GO:0010038
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010038
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. [GOC:sm]


systematic_name: M16655
exact_source: GO:0010039
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010039
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. [GOC:sm]


systematic_name: M40373
exact_source: GO:0010040
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010040
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus. [GOC:sm]


systematic_name: M16546
exact_source: GO:0010042
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010042
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus. [GOC:sm]


systematic_name: M10390
exact_source: GO:0010043
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010043
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. [GOC:sm]


systematic_name: M22610
exact_source: GO:0010092
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010092
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized. [GOC:tb]


systematic_name: M14164
exact_source: GO:0010155
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010155
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:sm]


systematic_name: M15358
exact_source: GO:0010165
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010165
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). [GOC:sm, Wikipedia:X-ray]


systematic_name: M10308
exact_source: GO:0010171
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010171
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the soma are generated and organized. [GOC:ems, ISBN:0140512888]


systematic_name: M22612
exact_source: GO:0010172
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010172
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which the anatomical structures of the embryonic soma are generated and organized. [GOC:ems]


systematic_name: M22613
exact_source: GO:0010182
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010182
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes. [PMID:9014361]


systematic_name: M42661
exact_source: GO:0010193
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010193
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus. [GOC:sm]


systematic_name: M10262
exact_source: GO:0010212
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010212
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. [PMID:12509526]


systematic_name: M16501
exact_source: GO:0010224
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010224
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. [GOC:tb]


systematic_name: M10139
exact_source: GO:0010225
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010225
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. [GOC:tb]


systematic_name: M14953
exact_source: GO:0010226
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010226
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. [GOC:tb]


systematic_name: M34087
exact_source: GO:0010232
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010232
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane. [GOC:sm]


systematic_name: M10147
exact_source: GO:0010248
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010248
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore. [GOC:mah, GOC:sm]


systematic_name: M13914
exact_source: GO:0010256
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010256
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. [GOC:mah, GOC:sm]


systematic_name: M22615
exact_source: GO:0010257
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010257
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex. [GOC:sm]


systematic_name: M22617
exact_source: GO:0010269
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010269
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion. [GOC:mg]


systematic_name: M46739
exact_source: GO:0010273
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010273
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion. [GOC:kmv, PMID:16367966]


systematic_name: M22618
exact_source: GO:0010286
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010286
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases heat tolerance of an organism in response to high temperatures. [GOC:tair_curators]


systematic_name: M16615
exact_source: GO:0010288
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010288
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus. [GOC:tair_curators, PMID:16461380]


systematic_name: M15219
exact_source: GO:0010310
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010310
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. [PMID:14765119]


systematic_name: M14914
exact_source: GO:0010332
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010332
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. [GOC:tair_curators]


systematic_name: M22620
exact_source: GO:0010387
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010387
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome. [PMID:17307927]


systematic_name: M34088
exact_source: GO:0010430
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010430
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation. [MetaCyc:PWY-2724, PMID:16404574]


systematic_name: M15520
exact_source: GO:0010447
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010447
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution. [GOC:go_curators, GOC:tb, Wikipedia:PH]


systematic_name: M16856
exact_source: GO:0010453
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010453
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. [GOC:dph, GOC:tb]


systematic_name: M22622
exact_source: GO:0010454
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010454
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. [GOC:dph, GOC:tb]


systematic_name: M10583
exact_source: GO:0010455
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010455
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. [GOC:dph, GOC:tb]


systematic_name: M22623
exact_source: GO:0010457
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010457
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle process in which the two centrioles within a centrosome remain tightly paired. [GOC:dph, GOC:tb]


systematic_name: M12894
exact_source: GO:0010458
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010458
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. [GOC:dph, GOC:tb]


systematic_name: M22624
exact_source: GO:0010459
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010459
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents or reduces the frequency or rate of heart contraction. [GOC:dph, GOC:tb]


systematic_name: M12377
exact_source: GO:0010460
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010460
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency or rate of heart contraction. [GOC:dph, GOC:tb]


systematic_name: M15086
exact_source: GO:0010463
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010463
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:dph, GOC:tb]


systematic_name: M12439
exact_source: GO:0010464
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010464
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. [GOC:dph, GOC:tb]


systematic_name: M16870
exact_source: GO:0010466
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010466
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. [GOC:dph, GOC:tb]


systematic_name: M22625
exact_source: GO:0010469
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010469
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. [GOC:dph, GOC:tb]


systematic_name: M14070
exact_source: GO:0010470
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010470
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. [GOC:dph, GOC:tb]


systematic_name: M15332
exact_source: GO:0010498
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010498
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. [GOC:tb]


systematic_name: M10281
exact_source: GO:0010506
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010506
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb]


systematic_name: M12149
exact_source: GO:0010507
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010507
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb]


systematic_name: M15852
exact_source: GO:0010508
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010508
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. [GOC:dph, GOC:tb]


systematic_name: M22627
exact_source: GO:0010511
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010511
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol. [GOC:dph, GOC:tb, GOC:vw]


systematic_name: M13050
exact_source: GO:0010517
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010517
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M42663
exact_source: GO:0010518
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010518
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22629
exact_source: GO:0010519
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010519
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M13541
exact_source: GO:0010522
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010522
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. [GOC:dph, GOC:tb]


systematic_name: M14062
exact_source: GO:0010524
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010524
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components. [GOC:dph, GOC:tb]


systematic_name: M22631
exact_source: GO:0010533
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010533
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. [GOC:dph, GOC:tb, PMID:17190829, PMID:9135582]


systematic_name: M14994
exact_source: GO:0010543
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010543
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M10805
exact_source: GO:0010544
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010544
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12940
exact_source: GO:0010562
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010562
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. [GOC:dph, GOC:tb]


systematic_name: M13280
exact_source: GO:0010563
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010563
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. [GOC:dph, GOC:tb]


systematic_name: M15760
exact_source: GO:0010564
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010564
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [GOC:dph, GOC:tb]


systematic_name: M13102
exact_source: GO:0010565
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010565
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. [GOC:dph, GOC:tb]


systematic_name: M22635
exact_source: GO:0010566
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010566
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. [GOC:dph, GOC:tb]


systematic_name: M11429
exact_source: GO:0010569
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010569
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. [GOC:dph, GOC:jp, GOC:tb]


systematic_name: M22636
exact_source: GO:0010571
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010571
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. [GOC:mtg_cell_cycle]


systematic_name: M42664
exact_source: GO:0010572
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010572
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M22638
exact_source: GO:0010573
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010573
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:rl]


systematic_name: M16809
exact_source: GO:0010575
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010575
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor. [GOC:BHF, GOC:rl]


systematic_name: M22639
exact_source: GO:0010586
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010586
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. [PMID:17993620]


systematic_name: M22640
exact_source: GO:0010587
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010587
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression. [PMID:17993620]


systematic_name: M11612
exact_source: GO:0010591
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010591
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. [GOC:dph, GOC:tb]


systematic_name: M13928
exact_source: GO:0010592
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010592
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. [GOC:dph, GOC:tb]


systematic_name: M22641
exact_source: GO:0010593
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010593
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. [GOC:dph, GOC:tb]


systematic_name: M12838
exact_source: GO:0010594
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010594
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12005
exact_source: GO:0010595
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010595
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22642
exact_source: GO:0010603
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010603
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. [GOC:dph, GOC:krc, GOC:tb]


systematic_name: M45084
exact_source: GO:0010606
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010606
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body. [GOC:dph, GOC:krc, GOC:tb]


systematic_name: M12155
exact_source: GO:0010608
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010608
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. [GOC:dph, GOC:tb]


systematic_name: M22644
exact_source: GO:0010612
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010612
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. [GOC:dph, GOC:tb]


systematic_name: M22645
exact_source: GO:0010615
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010615
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22646
exact_source: GO:0010616
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010616
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22647
exact_source: GO:0010623
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010623
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The activation of endogenous cellular processes that result in the death of a cell as part of its development. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M22648
exact_source: GO:0010626
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010626
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. [GOC:dph, GOC:sl, GOC:tb]


systematic_name: M40375
exact_source: GO:0010628
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010628
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018]


systematic_name: M40376
exact_source: GO:0010629
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010629
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). [GOC:txnOH-2018]


systematic_name: M11069
exact_source: GO:0010632
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010632
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of epithelial cell migration. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M12808
exact_source: GO:0010633
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010633
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M14851
exact_source: GO:0010634
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010634
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that activates or increases the frequency, rate or extent of epithelial cell migration. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22649
exact_source: GO:0010635
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010635
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. [GOC:dph, GOC:tb]


systematic_name: M48381
exact_source: GO:0010636
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010636
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. [GOC:dph, GOC:tb]


systematic_name: M22650
exact_source: GO:0010637
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010637
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. [GOC:dph, GOC:tb]


systematic_name: M11547
exact_source: GO:0010638
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010638
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. [GOC:dph, GOC:tb]


systematic_name: M16234
exact_source: GO:0010639
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010639
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. [GOC:dph, GOC:tb]


systematic_name: M15978
exact_source: GO:0010640
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010640
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. [GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M22651
exact_source: GO:0010641
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010641
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. [GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M22652
exact_source: GO:0010642
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010642
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. [GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M13301
exact_source: GO:0010644
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010644
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. [GOC:dph, GOC:kmv, GOC:tb]


systematic_name: M14633
exact_source: GO:0010649
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010649
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels. [GOC:dph, GOC:kmv, GOC:tb]


systematic_name: M12233
exact_source: GO:0010656
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010656
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M22653
exact_source: GO:0010657
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010657
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M22654
exact_source: GO:0010658
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010658
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M16552
exact_source: GO:0010661
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010661
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M22655
exact_source: GO:0010663
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010663
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. [GOC:dph, GOC:mtg_apoptosis, GOC:tb]


systematic_name: M16715
exact_source: GO:0010664
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010664
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb]


systematic_name: M22656
exact_source: GO:0010668
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010668
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GOC:dph, GOC:tb]


systematic_name: M15560
exact_source: GO:0010669
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010669
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  A tissue homeostatic process required for the maintenance of epithelial structure. [GOC:dph, GOC:tb]


systematic_name: M22661
exact_source: GO:0010700
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010700
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. [GOC:dph, GOC:tb]


systematic_name: M42665
exact_source: GO:0010706
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010706
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. [GOC:bf, GOC:dph, GOC:tb]


systematic_name: M29095
exact_source: GO:0010712
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010712
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. [GOC:dph, GOC:tb]


systematic_name: M29096
exact_source: GO:0010713
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010713
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. [GOC:dph, GOC:tb]


systematic_name: M29097
exact_source: GO:0010714
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010714
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. [GOC:dph, GOC:tb]


systematic_name: M15732
exact_source: GO:0010715
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010715
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M22662
exact_source: GO:0010716
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010716
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M16783
exact_source: GO:0010717
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010717
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M10621
exact_source: GO:0010718
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010718
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M11446
exact_source: GO:0010719
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010719
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M15451
exact_source: GO:0010720
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010720
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M10301
exact_source: GO:0010721
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010721
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. [GOC:BHF, GOC:dph, GOC:tb]


systematic_name: M34089
exact_source: GO:0010726
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010726
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. [GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M34090
exact_source: GO:0010727
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010727
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide. [GOC:dph, GOC:hjd, GOC:tb]


systematic_name: M22663
exact_source: GO:0010728
external_details_URL: http://amigo.geneontology.org/amigo/term/GO:0010728
source_species_code: HS
contributor: Gene Ontology
contrib_organization: Gene Ontology Consortium
description_brief:
  Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. [GOC:dph, GOC:hjd, GOC:tb]


