# gene_set_license

license_code: KEGG
license_name: Other KEGG data in MSigDB
license_note:
  MSigDB gene sets derived from KEGG pathways are protected by copyright, (c) 1995-2017 Kanehisa Laboratories, all rights reserved. They are provided for use in the MSigDB collection under license to the Broad Institute, Inc., with qualified permission to include in this release. End users are directed to http://www.pathway.jp/ and http://www.kegg.jp/kegg/docs/plea.html for information on the copyright holder's academic and commercial licensing policies. Inclusion of these gene sets herein is conditioned upon acknowledgment and retention of the aforementioned copyright, and compliance with such policies. The KEGG derived gene sets are in a subcollection of MSigDB C2 named KEGG_LEGACY, and can be recognized by the "KEGG_" prefix (without "MEDICUS") in their name.


license_code: BIOCARTA
license_name: BioCarta data in MSigDB
license_note:
  MSigDB gene sets derived from BioCarta pathways are protected by copyright, (c) 2000-2017 BioCarta, all rights reserved. They are provided under license to the Broad Institute, Inc. with qualified permission to include in this release, subject to Biocarta's "Disclaimer of Liability and of Warranties" (formerly found at www.biocarta.com). Inclusion of these gene sets is conditioned upon acknowledgment and retention of the aforementioned copyright, and agreement to such disclaimer. The BioCarta derived gene sets are in the MSigDB C2 and M2 collections, and can be recognized by the "BIOCARTA_" prefix in their name.


# publication

PMID: 10521349
DOI: 10521349
title:
  Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.


PMID: 10737792
DOI: 10737792
title:
  Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion.


PMID: 10756030
DOI: 10756030
title:
  Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31.


PMID: 10969808
DOI: 10969808
title:
  Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer.


PMID: 11279020
DOI: 11279020
title:
  Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics.


PMID: 11279127
DOI: 11279127
title:
  Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.


PMID: 11309484
DOI: 11309484
title:
  Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys.


PMID: 11313881
DOI: 11313881
title:
  Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2.


PMID: 11416145
DOI: 11416145
title:
  Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis.


PMID: 11487589
DOI: 11487589
title:
  A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling.


PMID: 11493461
DOI: 11493461
title:
  Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells.


PMID: 11522623
DOI: 11522623
title:
  Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis.


PMID: 11532376
DOI: 11532376
title:
  Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation.


PMID: 11711622
DOI: 11711622
title:
  Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: viral block to the accumulation of antiviral mRNAs.


PMID: 11719506
DOI: 11719506
title:
  Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation.


PMID: 11741835
DOI: 11741835
title:
  DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes.


PMID: 11755394
DOI: 11755394
title:
  Antitumor activity- and gene expression-based profiling of ecteinascidin Et 743 and phthalascidin Pt 650.


PMID: 11786909
DOI: 11786909
title:
  Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning.


PMID: 11830491
DOI: 11830491
title:
  Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2.


PMID: 11861292
DOI: 11861292
title:
  Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.


PMID: 11861364
DOI: 11861364
title:
  Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.


PMID: 11867723
DOI: 11867723
title:
  Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis.


PMID: 11867738
DOI: 11867738
title:
  Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays.


PMID: 11910354
DOI: 11910354
title:
  Interferon-alpha activates multiple STAT signals and down-regulates c-Met in primary human hepatocytes.


PMID: 11960025
DOI: 11960025
title:
  Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.


PMID: 11991981
DOI: 11991981
title:
  Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes.


PMID: 11992124
DOI: 11992124
title:
  A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.


PMID: 12021175
DOI: 12021175
title:
  Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists.


PMID: 12057921
DOI: 12057921
title:
  Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition.


PMID: 12058064
DOI: 12058064
title:
  Identification of genes periodically expressed in the human cell cycle and their expression in tumors.


PMID: 12101249
DOI: 12101249
title:
  The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.


PMID: 12130493
DOI: 12130493
title:
  Development of a murine hematopoietic progenitor complementary DNA microarray using a subtracted complementary DNA library.


PMID: 12197474
DOI: 12197474
title:
  cDNA microarray analysis of the gene expression profile of VEGF-activated human umbilical vein endothelial cells.


PMID: 12198119
DOI: 12198119
title:
  Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis.


PMID: 12198161
DOI: 12198161
title:
  Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor.


PMID: 12213819
DOI: 12213819
title:
  Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1.


PMID: 12234922
DOI: 12234922
title:
  Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1.


PMID: 12354774
DOI: 12354774
title:
  Differential gene regulation by specific gain-of-function JNK1 proteins expressed in Swiss 3T3 fibroblasts.


PMID: 12356685
DOI: 12356685
title:
  Global reprogramming of dendritic cells in response to a concerted action of inflammatory mediators.


PMID: 12379459
DOI: 12379459
title:
  Differential gene expression in gamma-irradiated BALB/3T3 fibroblasts under the influence of 3-aminobenzamide, an inhibitior of parp enzyme.


PMID: 12381414
DOI: 12381414
title:
  A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion.


PMID: 12393420
DOI: 12393420
title:
  Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival.


PMID: 12393520
DOI: 12393520
title:
  Gene expression profiling of human plasma cell differentiation and classification of multiple myeloma based on similarities to distinct stages of late-stage B-cell development.


PMID: 12411303
DOI: 12411303
title:
  CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays.


PMID: 12414654
DOI: 12414654
title:
  Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.


PMID: 12418965
DOI: 12418965
title:
  Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations.


PMID: 12446780
DOI: 12446780
title:
  Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.


PMID: 12447701
DOI: 12447701
title:
  A microarray-based, integrated approach to identify novel regulators of cancer drug response and apoptosis.


PMID: 12471561
DOI: 12471561
title:
  Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.


PMID: 12479369
DOI: 12479369
title:
  Mechanisms of resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma.


PMID: 12480690
DOI: 12480690
title:
  Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays.


PMID: 12531789
DOI: 12531789
title:
  Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts.


PMID: 12540486
DOI: 12540486
title:
  Inhibition of nitric oxide restores surfactant gene expression following nickel-induced acute lung injury.


PMID: 12554760
DOI: 12554760
title:
  Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus.


PMID: 12604609
DOI: 12604609
title:
  Mammalian elongin A is not essential for cell viability but is required for proper cell cycle progression with limited alteration of gene expression.


PMID: 12606941
DOI: 12606941
title:
  The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells.


PMID: 12618007
DOI: 12618007
title:
  Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes.


PMID: 12623842
DOI: 12623842
title:
  Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease.


PMID: 12637319
DOI: 12637319
title:
  Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.


PMID: 12648972
DOI: 12648972
title:
  Oligonucleotide microarray for prediction of early intrahepatic recurrence of hepatocellular carcinoma after curative resection.


PMID: 12663451
DOI: 12663451
title:
  Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites.


PMID: 12663452
DOI: 12663452
title:
  Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation.


PMID: 12670911
DOI: 12670911
title:
  Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.


PMID: 12673201
DOI: 12673201
title:
  Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin.


PMID: 12673210
DOI: 12673210
title:
  Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference.


PMID: 12682234
DOI: 12682234
title:
  Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation.


PMID: 12692265
DOI: 12692265
title:
  Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways.


PMID: 12702554
DOI: 12702554
title:
  Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene.


PMID: 12704389
DOI: 12704389
title:
  Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells.


PMID: 12719586
DOI: 12719586
title:
  Ribavirin treatment up-regulates antiviral gene expression via the interferon-stimulated response element in respiratory syncytial virus-infected epithelial cells.


PMID: 12732648
DOI: 12732648
title:
  Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB.


PMID: 12766259
DOI: 12766259
title:
  cDNA microarray analysis reveals a nuclear factor-kappaB-independent regulation of macrophage function by adenosine.


PMID: 12771951
DOI: 12771951
title:
  Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.


PMID: 12791645
DOI: 12791645
title:
  Gene profiling of a myeloma cell line reveals similarities and unique signatures among IL-6 response, N-ras-activating mutations, and coculture with bone marrow stromal cells.


PMID: 12808457
DOI: 12808457
title:
  PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.


PMID: 12816982
DOI: 12816982
title:
  Relationships among murine CD11c(high) dendritic cell subsets as revealed by baseline gene expression patterns.


PMID: 12824169
DOI: 12824169
title:
  Identification of Aeromonas hydrophila cytotoxic enterotoxin-induced genes in macrophages using microarrays.


PMID: 12824457
DOI: 12824457
title:
  Alterations of gene expression in failing myocardium following left ventricular assist device support.


PMID: 12832290
DOI: 12832290
title:
  Novel genes modulated by FSH in normal and immortalized FSH-responsive cells: new insights into the mechanism of FSH action.


PMID: 12839967
DOI: 12839967
title:
  Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.


PMID: 12855579
DOI: 12855579
title:
  Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and FcepsilonRI.


PMID: 12885785
DOI: 12885785
title:
  The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia.


PMID: 12885910
DOI: 12885910
title:
  Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis.


PMID: 12893766
DOI: 12893766
title:
  Comparative analysis of genes regulated by PML/RAR alpha and PLZF/RAR alpha in response to retinoic acid using oligonucleotide arrays.


PMID: 12907719
DOI: 12907719
title:
  Cell cycle arrest and apoptosis provoked by UV radiation-induced DNA damage are transcriptionally highly divergent responses.


PMID: 12915101
DOI: 12915101
title:
  Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II).


PMID: 12969979
DOI: 12969979
title:
  Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation.


PMID: 14508521
DOI: 14508521
title:
  Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.


PMID: 14512514
DOI: 14512514
title:
  Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes.


PMID: 14517214
DOI: 14517214
title:
  Restoration of C/EBPalpha expression in a BCR-ABL+ cell line induces terminal granulocytic differentiation.


PMID: 14517420
DOI: 14517420
title:
  Transcriptional profiling of human microvascular endothelial cells in the proliferative and quiescent state using cDNA arrays.


PMID: 14519204
DOI: 14519204
title:
  An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets.


PMID: 14525773
DOI: 14525773
title:
  Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow.


PMID: 14530283
DOI: 14530283
title:
  Expression profiling identifies genes that continue to respond to insulin in adipocytes made insulin-resistant by treatment with tumor necrosis factor-alpha.


PMID: 14576184
DOI: 14576184
title:
  Cell-specific pituitary gene expression profiles after treatment with leukemia inhibitory factor reveal novel modulators for proopiomelanocortin expression.


PMID: 14607935
DOI: 14607935
title:
  Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes.


PMID: 14639605
DOI: 14639605
title:
  Analysis of gene expression profiles in human HL-60 cell exposed to cantharidin using cDNA microarray.


PMID: 14676830
DOI: 14676830
title:
  Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis.


PMID: 14684422
DOI: 14684422
title:
  Gene expression profile of adult T-cell acute lymphocytic leukemia identifies distinct subsets of patients with different response to therapy and survival.


PMID: 14701746
DOI: 14701746
title:
  Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitro.


PMID: 14707115
DOI: 14707115
title:
  Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors.


PMID: 14734480
DOI: 14734480
title:
  Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays.


PMID: 14737109
DOI: 14737109
title:
  A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance.


PMID: 14737219
DOI: 14737219
title:
  Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.


PMID: 14769913
DOI: 14769913
title:
  Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses.


PMID: 14973077
DOI: 14973077
title:
  The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors.


PMID: 14973112
DOI: 14973112
title:
  Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells.


PMID: 14981515
DOI: 14981515
title:
  Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis.


PMID: 15024077
DOI: 15024077
title:
  Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.


PMID: 15026540
DOI: 15026540
title:
  Gonadotrophin-induced gene regulation in human granulosa cells obtained from IVF patients. Modulation of steroidogenic genes, cytoskeletal genes and genes coding for apoptotic signalling and protein kinases.


PMID: 15031206
DOI: 15031206
title:
  Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease.


PMID: 15033468
DOI: 15033468
title:
  DNA microarray analysis of the correlation between gene expression patterns and acquired resistance to 5-FU/cisplatin in gastric cancer.


PMID: 15033914
DOI: 15033914
title:
  Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) alpha or ERbeta in human osteosarcoma cells: distinct and common target genes for these receptors.


PMID: 15103417
DOI: 15103417
title:
  Global gene expression in human myocardium-oligonucleotide microarray analysis of regional diversity and transcriptional regulation in heart failure.


PMID: 15107491
DOI: 15107491
title:
  The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation.


PMID: 15120960
DOI: 15120960
title:
  Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins.


PMID: 15131130
DOI: 15131130
title:
  Role of nuclear factor-kappaB in the antiviral action of interferon and interferon-regulated gene expression.


PMID: 15133507
DOI: 15133507
title:
  Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells.


PMID: 15155749
DOI: 15155749
title:
  Genomic mechanisms of p210BCR-ABL signaling: induction of heat shock protein 70 through the GATA response element confers resistance to paclitaxel-induced apoptosis.


PMID: 15156201
DOI: 15156201
title:
  mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.


PMID: 15184677
DOI: 15184677
title:
  Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression.


PMID: 15187151
DOI: 15187151
title:
  The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing.


PMID: 15189810
DOI: 15189810
title:
  Microarray analyses identify JAK2 tyrosine kinase as a key mediator of ligand-independent gene expression.


PMID: 15205324
DOI: 15205324
title:
  A transcriptional profiling study of CCAAT/enhancer binding protein targets identifies hepatocyte nuclear factor 3 beta as a novel tumor suppressor in lung cancer.


PMID: 15252187
DOI: 15252187
title:
  Erythroid-induced commitment of K562 cells results in clusters of differentially expressed genes enriched for specific transcription regulatory elements.


PMID: 15273285
DOI: 15273285
title:
  Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles.


PMID: 15295046
DOI: 15295046
title:
  Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.


PMID: 15302890
DOI: 15302890
title:
  Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation.


PMID: 15302897
DOI: 15302897
title:
  Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays.


PMID: 15303102
DOI: 15303102
title:
  Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder.


PMID: 15307835
DOI: 15307835
title:
  Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes.


PMID: 15310760
DOI: 15310760
title:
  Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes.


PMID: 15318170
DOI: 15318170
title:
  Expression profiling of sodium butyrate (NaB)-treated cells: identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB.


PMID: 15331438
DOI: 15331438
title:
  Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood.


PMID: 15336447
DOI: 15336447
title:
  Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.


PMID: 15339848
DOI: 15339848
title:
  Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis.


PMID: 15386376
DOI: 15386376
title:
  Follicle stimulating hormone-induced growth promotion and gene expression profiles on ovarian surface epithelial cells.


PMID: 15388584
DOI: 15388584
title:
  Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis.


PMID: 15452378
DOI: 15452378
title:
  Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells.


PMID: 15459216
DOI: 15459216
title:
  Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status.


PMID: 15467722
DOI: 15467722
title:
  Amplification of IFN-alpha-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors.


PMID: 15471956
DOI: 15471956
title:
  Overexpression of a cell adhesion molecule, TSLC1, as a possible molecular marker for acute-type adult T-cell leukemia.


PMID: 15475267
DOI: 15475267
title:
  Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.


PMID: 15485929
DOI: 15485929
title:
  Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.


PMID: 15492243
DOI: 15492243
title:
  The nuclear factor kappaB subunits RelA/p65 and c-Rel potentiate but are not required for Ras-induced cellular transformation.


PMID: 15515172
DOI: 15515172
title:
  Comparison of gene expression changes induced in mouse and human cells treated with direct-acting mutagens.


PMID: 15516835
DOI: 15516835
title:
  Bioinformatic analysis of primary endothelial cell gene array data illustrated by the analysis of transcriptome changes in endothelial cells exposed to VEGF-A and PlGF.


PMID: 15516973
DOI: 15516973
title:
  Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.


PMID: 15531917
DOI: 15531917
title:
  Transcript profiling of Wilms tumors reveals connections to kidney morphogenesis and expression patterns associated with anaplasia.


PMID: 15548687
DOI: 15548687
title:
  DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets.


PMID: 15558012
DOI: 15558012
title:
  Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential.


PMID: 15558013
DOI: 15558013
title:
  Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity.


PMID: 15561778
DOI: 15561778
title:
  Bcl-2 overexpression leads to increases in suppressor of cytokine signaling-3 expression in B cells and de novo follicular lymphoma.


PMID: 15565109
DOI: 15565109
title:
  Application of comparative functional genomics to identify best-fit mouse models to study human cancer.


PMID: 15579653
DOI: 15579653
title:
  Expression of telomerase extends the lifespan and enhances osteogenic differentiation of adipose tissue-derived stromal cells.


PMID: 15580292
DOI: 15580292
title:
  A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8.


PMID: 15591113
DOI: 15591113
title:
  Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas.


PMID: 15592430
DOI: 15592430
title:
  FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development.


PMID: 15592509
DOI: 15592509
title:
  The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.


PMID: 15592526
DOI: 15592526
title:
  Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.


PMID: 15592527
DOI: 15592527
title:
  Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.


PMID: 15601821
DOI: 15601821
title:
  CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.


PMID: 15608674
DOI: 15608674
title:
  Inositol 1,4,5-trisphosphate (IP3) receptor type1 (IP3R1) modulates the acquisition of cisplatin resistance in bladder cancer cell lines.


PMID: 15608677
DOI: 15608677
title:
  Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage.


PMID: 15608684
DOI: 15608684
title:
  Transcriptional profiles of unirradiated or UV-irradiated human cells expressing either the cancer-prone XPB/CS allele or the noncancer-prone XPB/TTD allele.


PMID: 15608685
DOI: 15608685
title:
  dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53.


PMID: 15608688
DOI: 15608688
title:
  Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPAR(gamma) fusion oncogene.


PMID: 15619625
DOI: 15619625
title:
  Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene.


PMID: 15635089
DOI: 15635089
title:
  Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture.


PMID: 15637585
DOI: 15637585
title:
  Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells.


PMID: 15637593
DOI: 15637593
title:
  Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.


PMID: 15657362
DOI: 15657362
title:
  Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.


PMID: 15661559
DOI: 15661559
title:
  Molecular characterisation of two human cancer cell lines selected in vitro for their chemotherapeutic drug resistance to ET-743.


PMID: 15661827
DOI: 15661827
title:
  Thymocyte stimulation by anti-TCR-beta, but not by anti-TCR-alpha, leads to induction of developmental transcription program.


PMID: 15664994
DOI: 15664994
title:
  Signal transducers and activators of transcription 3 augments the transcriptional activity of CCAAT/enhancer-binding protein alpha in granulocyte colony-stimulating factor signaling pathway.


PMID: 15674340
DOI: 15674340
title:
  Latent membrane protein 1 of Epstein-Barr virus coordinately regulates proliferation with control of apoptosis.


PMID: 15674343
DOI: 15674343
title:
  Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype.


PMID: 15674348
DOI: 15674348
title:
  Epidermal growth factor-induced hepatocellular carcinoma: gene expression profiles in precursor lesions, early stage and solitary tumours.


PMID: 15688027
DOI: 15688027
title:
  Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications.


PMID: 15691874
DOI: 15691874
title:
  Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins.


PMID: 15695336
DOI: 15695336
title:
  Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination.


PMID: 15710396
DOI: 15710396
title:
  Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma.


PMID: 15711545
DOI: 15711545
title:
  Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function.


PMID: 15711547
DOI: 15711547
title:
  Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.


PMID: 15721472
DOI: 15721472
title:
  Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer.


PMID: 15722553
DOI: 15722553
title:
  Identification of direct genomic targets downstream of the nuclear factor-kappaB transcription factor mediating tumor necrosis factor signaling.


PMID: 15735639
DOI: 15735639
title:
  Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.


PMID: 15735679
DOI: 15735679
title:
  Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein.


PMID: 15735714
DOI: 15735714
title:
  An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma.


PMID: 15735726
DOI: 15735726
title:
  Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.


PMID: 15735737
DOI: 15735737
title:
  Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma.


PMID: 15738394
DOI: 15738394
title:
  Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors.


PMID: 15749026
DOI: 15749026
title:
  Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines.


PMID: 15750623
DOI: 15750623
title:
  Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice.


PMID: 15755900
DOI: 15755900
title:
  Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.


PMID: 15756019
DOI: 15756019
title:
  Effects of imatinib on monocyte-derived dendritic cells are mediated by inhibition of nuclear factor-kappaB and Akt signaling pathways.


PMID: 15769904
DOI: 15769904
title:
  Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.


PMID: 15789058
DOI: 15789058
title:
  Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.


PMID: 15806164
DOI: 15806164
title:
  Gene profiling reveals specific oncogenic mechanisms and signaling pathways in oncocytic and papillary thyroid carcinoma.


PMID: 15824737
DOI: 15824737
title:
  Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma.


PMID: 15827134
DOI: 15827134
title:
  The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.


PMID: 15831586
DOI: 15831586
title:
  Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.


PMID: 15831697
DOI: 15831697
title:
  Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.


PMID: 15843551
DOI: 15843551
title:
  Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes.


PMID: 15845533
DOI: 15845533
title:
  Gene expression profiling to identify oncogenic determinants of autocrine human growth hormone in human mammary carcinoma.


PMID: 15856012
DOI: 15856012
title:
  Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.


PMID: 15856024
DOI: 15856024
title:
  Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes.


PMID: 15864312
DOI: 15864312
title:
  Identification of MMP-1 as a putative breast cancer predictive marker by global gene expression analysis.


PMID: 15870273
DOI: 15870273
title:
  MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex.


PMID: 15879137
DOI: 15879137
title:
  Insights into pathogen immune evasion mechanisms: Anaplasma phagocytophilum fails to induce an apoptosis differentiation program in human neutrophils.


PMID: 15892871
DOI: 15892871
title:
  Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis.


PMID: 15895078
DOI: 15895078
title:
  Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin.


PMID: 15897246
DOI: 15897246
title:
  Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients.


PMID: 15897868
DOI: 15897868
title:
  Array-based comparative gene expression analysis of tumor cells with increased apoptosis resistance after hypoxic selection.


PMID: 15897875
DOI: 15897875
title:
  Paired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras gene.


PMID: 15897880
DOI: 15897880
title:
  All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo.


PMID: 15897883
DOI: 15897883
title:
  Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice.


PMID: 15928199
DOI: 15928199
title:
  New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.


PMID: 15930281
DOI: 15930281
title:
  EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors.


PMID: 15931389
DOI: 15931389
title:
  Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer.


PMID: 15940259
DOI: 15940259
title:
  A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma.


PMID: 15940270
DOI: 15940270
title:
  Discrimination between serous low malignant potential and invasive epithelial ovarian tumors using molecular profiling.


PMID: 15958647
DOI: 15958647
title:
  The transforming growth factor-beta family members bone morphogenetic protein-2 and macrophage inhibitory cytokine-1 as mediators of the antiangiogenic activity of N-(4-hydroxyphenyl)retinamide.


PMID: 15980968
DOI: 15980968
title:
  Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression.


PMID: 15995707
DOI: 15995707
title:
  Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells.


PMID: 16006652
DOI: 16006652
title:
  Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.


PMID: 16007088
DOI: 16007088
title:
  Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells.


PMID: 16007138
DOI: 16007138
title:
  Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization.


PMID: 16007141
DOI: 16007141
title:
  Identification of a proliferation gene cluster associated with HPV E6/E7 expression level and viral DNA load in invasive cervical carcinoma.


PMID: 16007187
DOI: 16007187
title:
  Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer.


PMID: 16007190
DOI: 16007190
title:
  HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.


PMID: 16007217
DOI: 16007217
title:
  Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation.


PMID: 16044152
DOI: 16044152
title:
  Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.


PMID: 16077073
DOI: 16077073
title:
  Disease-independent skin recruitment and activation of plasmacytoid predendritic cells following imiquimod treatment.


PMID: 16103878
DOI: 16103878
title:
  ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation.


PMID: 16105978
DOI: 16105978
title:
  Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia.


PMID: 16109776
DOI: 16109776
title:
  Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance.


PMID: 16116230
DOI: 16116230
title:
  Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation.


PMID: 16116477
DOI: 16116477
title:
  Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification.


PMID: 16116479
DOI: 16116479
title:
  Profiling estrogen-regulated gene expression changes in normal and malignant human ovarian surface epithelial cells.


PMID: 16127159
DOI: 16127159
title:
  Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice.


PMID: 16127434
DOI: 16127434
title:
  Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells.


PMID: 16135788
DOI: 16135788
title:
  The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene.


PMID: 16140920
DOI: 16140920
title:
  IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide.


PMID: 16140955
DOI: 16140955
title:
  Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.


PMID: 16148108
DOI: 16148108
title:
  IFN-gamma-primed macrophages exhibit increased CCR2-dependent migration and altered IFN-gamma responses mediated by Stat1.


PMID: 16158056
DOI: 16158056
title:
  Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer.


PMID: 16160012
DOI: 16160012
title:
  ZAP-70 expression in acute lymphoblastic leukemia: association with the E2A/PBX1 rearrangement and the pre-B stage of differentiation and prognostic implications.


PMID: 16186804
DOI: 16186804
title:
  Histone deacetylase inhibitor FK228 suppresses the Ras-MAP kinase signaling pathway by upregulating Rap1 and induces apoptosis in malignant melanoma.


PMID: 16199517
DOI: 16199517
title:
  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.


PMID: 16205638
DOI: 16205638
title:
  BCR-ABL1 induces aberrant splicing of IKAROS and lineage infidelity in pre-B lymphoblastic leukemia cells.


PMID: 16205646
DOI: 16205646
title:
  NOL7 is a nucleolar candidate tumor suppressor gene in cervical cancer that modulates the angiogenic phenotype.


PMID: 16207825
DOI: 16207825
title:
  Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout mice.


PMID: 16208318
DOI: 16208318
title:
  CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection.


PMID: 16247447
DOI: 16247447
title:
  Identification of novel genomic markers related to progression to glioblastoma through genomic profiling of 25 primary glioma cell lines.


PMID: 16247469
DOI: 16247469
title:
  Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3'-untranslated region interacting with a cellular protein in human chondrosarcoma cells.


PMID: 16247478
DOI: 16247478
title:
  Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells.


PMID: 16247483
DOI: 16247483
title:
  Identification of novel tumour-associated genes differentially expressed in the process of squamous cell cancer development.


PMID: 16261164
DOI: 16261164
title:
  Laser microdissection and microarray analysis of breast tumors reveal ER-alpha related genes and pathways.


PMID: 16278678
DOI: 16278678
title:
  Ha-ras(val12) induces HSP70b transcription via the HSE/HSF1 system, but HSP70b expression is suppressed in Ha-ras(val12)-transformed cells.


PMID: 16288221
DOI: 16288221
title:
  Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners.


PMID: 16301525
DOI: 16301525
title:
  Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.


PMID: 16314830
DOI: 16314830
title:
  Identification of genes differentially expressed in glioblastoma versus pilocytic astrocytoma using Suppression Subtractive Hybridization.


PMID: 16314831
DOI: 16314831
title:
  Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells.


PMID: 16314843
DOI: 16314843
title:
  Parallel induction of ATM-dependent pro- and antiapoptotic signals in response to ionizing radiation in murine lymphoid tissue.


PMID: 16314847
DOI: 16314847
title:
  Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations.


PMID: 16331246
DOI: 16331246
title:
  Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling.


PMID: 16331255
DOI: 16331255
title:
  Hodgkin's lymphoma cells express alternatively spliced forms of HDM2 with multiple effects on cell cycle control.


PMID: 16331256
DOI: 16331256
title:
  Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer.


PMID: 16357323
DOI: 16357323
title:
  T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells.


PMID: 16369491
DOI: 16369491
title:
  Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach.


PMID: 16380512
DOI: 16380512
title:
  Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock.


PMID: 16381821
DOI: 16381821
title:
  Gene expression in human thyrocytes and autonomous adenomas reveals suppression of negative feedbacks in tumorigenesis.


PMID: 16382050
DOI: 16382050
title:
  Functional validation of genes implicated in lymphomagenesis: an in vivo selection assay using a Myc-induced B-cell tumor.


PMID: 16394013
DOI: 16394013
title:
  Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells.


PMID: 16397028
DOI: 16397028
title:
  Prediction of lymph node metastasis in patients with endometrioid endometrial cancer using expression microarray.


PMID: 16407838
DOI: 16407838
title:
  Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.


PMID: 16423401
DOI: 16423401
title:
  Distinct gene expression in human Vdelta1 and Vdelta2 gammadelta T cells following non-TCR agonist stimulation.


PMID: 16424014
DOI: 16424014
title:
  Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors.


PMID: 16424048
DOI: 16424048
title:
  Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma.


PMID: 16424387
DOI: 16424387
title:
  Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells.


PMID: 16434967
DOI: 16434967
title:
  Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors.


PMID: 16434974
DOI: 16434974
title:
  The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes.


PMID: 16449969
DOI: 16449969
title:
  Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression.


PMID: 16449971
DOI: 16449971
title:
  Inhibition of tumor growth and metastasis in vitro and in vivo by targeting macrophage migration inhibitory factor in human neuroblastoma.


PMID: 16449976
DOI: 16449976
title:
  Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis.


PMID: 16467078
DOI: 16467078
title:
  Expression profiling of mucinous tumors of the ovary identifies genes of clinicopathologic importance.


PMID: 16467079
DOI: 16467079
title:
  Gene expression differences associated with human papillomavirus status in head and neck squamous cell carcinoma.


PMID: 16474848
DOI: 16474848
title:
  ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix.


PMID: 16478745
DOI: 16478745
title:
  Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis.


PMID: 16491115
DOI: 16491115
title:
  Identification of tumor markers and differentiation markers for molecular diagnosis of lung adenocarcinoma.


PMID: 16491124
DOI: 16491124
title:
  An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen.


PMID: 16492737
DOI: 16492737
title:
  Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.


PMID: 16501597
DOI: 16501597
title:
  Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-beta signaling.


PMID: 16501609
DOI: 16501609
title:
  Pleiotrophin, a candidate gene for poor tumor vasculature and in vivo neuroblastoma sensitivity to irinotecan.


PMID: 16507773
DOI: 16507773
title:
  c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.


PMID: 16507782
DOI: 16507782
title:
  Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes.


PMID: 16527888
DOI: 16527888
title:
  Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features.


PMID: 16531451
DOI: 16531451
title:
  Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis.


PMID: 16532037
DOI: 16532037
title:
  Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q.


PMID: 16540638
DOI: 16540638
title:
  Global gene expression profiling of circulating endothelial cells in patients with metastatic carcinomas.


PMID: 16540645
DOI: 16540645
title:
  Global gene expression profiling of pleural mesotheliomas: overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction.


PMID: 16551867
DOI: 16551867
title:
  Ingenuity network-assisted transcription profiling: Identification of a new pharmacologic mechanism for MK886.


PMID: 16565084
DOI: 16565084
title:
  Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways.


PMID: 16571413
DOI: 16571413
title:
  Immune activation at effector and gene expression levels after measles vaccination in healthy individuals: a pilot study.


PMID: 16585155
DOI: 16585155
title:
  Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles.


PMID: 16585179
DOI: 16585179
title:
  Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death.


PMID: 16585219
DOI: 16585219
title:
  Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors.


PMID: 16606835
DOI: 16606835
title:
  Cysteinyl leukotriene 2 receptor and protease-activated receptor 1 activate strongly correlated early genes in human endothelial cells.


PMID: 16611997
DOI: 16611997
title:
  Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression.


PMID: 16617321
DOI: 16617321
title:
  Deregulated expression of fat and muscle genes in B-cell chronic lymphocytic leukemia with high lipoprotein lipase expression.


PMID: 16619041
DOI: 16619041
title:
  Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells.


PMID: 16627760
DOI: 16627760
title:
  Genes contributing to minimal residual disease in childhood acute lymphoblastic leukemia: prognostic significance of CASP8AP2.


PMID: 16652140
DOI: 16652140
title:
  siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.


PMID: 16670265
DOI: 16670265
title:
  Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study.


PMID: 16702952
DOI: 16702952
title:
  A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.


PMID: 16707453
DOI: 16707453
title:
  Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysis.


PMID: 16710476
DOI: 16710476
title:
  Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype.


PMID: 16715129
DOI: 16715129
title:
  Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.


PMID: 16717116
DOI: 16717116
title:
  A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression.


PMID: 16732325
DOI: 16732325
title:
  Genomic profiling of bone and soft tissue tumors with supernumerary ring chromosomes using tiling resolution bacterial artificial chromosome microarrays.


PMID: 16741228
DOI: 16741228
title:
  Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia.


PMID: 16751804
DOI: 16751804
title:
  Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells.


PMID: 16769770
DOI: 16769770
title:
  Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling.


PMID: 16772382
DOI: 16772382
title:
  Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling.


PMID: 16774935
DOI: 16774935
title:
  Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells.


PMID: 16785517
DOI: 16785517
title:
  Galectin-1-matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix.


PMID: 16785988
DOI: 16785988
title:
  Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies.


PMID: 16785998
DOI: 16785998
title:
  Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays.


PMID: 16788156
DOI: 16788156
title:
  A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma.


PMID: 16799640
DOI: 16799640
title:
  Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues.


PMID: 16818636
DOI: 16818636
title:
  NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells.


PMID: 16832346
DOI: 16832346
title:
  The Ras-MAPK pathway downregulates Caveolin-1 in rodent fibroblast but not in human fibroblasts: implications in the resistance to oncogene-mediated transformation.


PMID: 16832351
DOI: 16832351
title:
  Differentially androgen-modulated genes in ovarian epithelial cells from BRCA mutation carriers and control patients predict ovarian cancer survival and disease progression.


PMID: 16843262
DOI: 16843262
title:
  Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.


PMID: 16849537
DOI: 16849537
title:
  Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas.


PMID: 16849555
DOI: 16849555
title:
  Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer.


PMID: 16849564
DOI: 16849564
title:
  Chemokine (C-C motif) ligand 2 mediates the prometastatic effect of dysadherin in human breast cancer cells.


PMID: 16849584
DOI: 16849584
title:
  Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome.


PMID: 16862181
DOI: 16862181
title:
  RB silencing compromises the DNA damage-induced G2/M checkpoint and causes deregulated expression of the ECT2 oncogene.


PMID: 16862182
DOI: 16862182
title:
  Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin-proteasome pathway as a therapeutic target in poor prognosis tumors.


PMID: 16862184
DOI: 16862184
title:
  Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression.


PMID: 16877703
DOI: 16877703
title:
  Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.


PMID: 16885346
DOI: 16885346
title:
  Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.


PMID: 16908595
DOI: 16908595
title:
  Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress.


PMID: 16909110
DOI: 16909110
title:
  Role of E2F3 expression in modulating cellular proliferation rate in human bladder and prostate cancer cells.


PMID: 16909116
DOI: 16909116
title:
  Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses.


PMID: 16912112
DOI: 16912112
title:
  Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids.


PMID: 16912175
DOI: 16912175
title:
  Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma.


PMID: 16914556
DOI: 16914556
title:
  Modulation of pro- and antiapoptotic molecules in double-positive (CD4+CD8+) thymocytes following dexamethasone treatment.


PMID: 16932341
DOI: 16932341
title:
  Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status.


PMID: 16951325
DOI: 16951325
title:
  Mechanisms regulating the proliferative potential of human CD8+ T lymphocytes overexpressing telomerase.


PMID: 16953217
DOI: 16953217
title:
  RIZ1 repression is associated with insulin-like growth factor-1 signaling activation in chronic myeloid leukemia cell lines.


PMID: 16954472
DOI: 16954472
title:
  Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification.


PMID: 16982809
DOI: 16982809
title:
  PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells.


PMID: 16983338
DOI: 16983338
title:
  Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.


PMID: 16983347
DOI: 16983347
title:
  Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.


PMID: 16990345
DOI: 16990345
title:
  Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells.


PMID: 16990782
DOI: 16990782
title:
  Identification of a molecular signature for leukemic promyelocytes and their normal counterparts: Focus on DNA repair genes.


PMID: 16998498
DOI: 16998498
title:
  Pathology and gene expression of hereditary breast tumors associated with BRCA1, BRCA2 and CHEK2 gene mutations.


PMID: 17001317
DOI: 17001317
title:
  Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers.


PMID: 17001320
DOI: 17001320
title:
  Identification of novel VHL targets that are associated with the development of renal cell carcinoma.


PMID: 17009164
DOI: 17009164
title:
  A gene expression profile for vascular invasion can predict the recurrence after resection of hepatocellular carcinoma: a microarray approach.


PMID: 17010674
DOI: 17010674
title:
  Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.


PMID: 17015706
DOI: 17015706
title:
  Establishment of lymphotoxin beta receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes.


PMID: 17016442
DOI: 17016442
title:
  Interferon regulatory factor-1 regulates reconstituted extracellular matrix (rECM)-mediated apoptosis in human mammary epithelial cells.


PMID: 17043644
DOI: 17043644
title:
  Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.


PMID: 17043662
DOI: 17043662
title:
  Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.


PMID: 17047040
DOI: 17047040
title:
  Distal colorectal cancers with microsatellite instability (MSI) display distinct gene expression profiles that are different from proximal MSI cancers.


PMID: 17072341
DOI: 17072341
title:
  Gene expression response to cisplatin treatment in drug-sensitive and drug-resistant ovarian cancer cells.


PMID: 17072343
DOI: 17072343
title:
  Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells.


PMID: 17082649
DOI: 17082649
title:
  Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression.


PMID: 17086209
DOI: 17086209
title:
  Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells.


PMID: 17088532
DOI: 17088532
title:
  Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.


PMID: 17099726
DOI: 17099726
title:
  Molecular profiling of docetaxel cytotoxicity in breast cancer cells: uncoupling of aberrant mitosis and apoptosis.


PMID: 17099727
DOI: 17099727
title:
  Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells.


PMID: 17101797
DOI: 17101797
title:
  The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma.


PMID: 17119049
DOI: 17119049
title:
  Genes involved in DNA repair and nitrosamine metabolism and those located on chromosome 14q32 are dysregulated in nasopharyngeal carcinoma.


PMID: 17130830
DOI: 17130830
title:
  Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.


PMID: 17142811
DOI: 17142811
title:
  Quantitative transcriptional control of ErbB receptor signaling undergoes graded to biphasic response for cell differentiation.


PMID: 17145885
DOI: 17145885
title:
  Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling.


PMID: 17146443
DOI: 17146443
title:
  The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells.


PMID: 17160024
DOI: 17160024
title:
  Chemotherapy resistance of mouse WAP-SVT/t breast cancer cells is mediated by osteopontin, inhibiting apoptosis downstream of caspase-3.


PMID: 17170726
DOI: 17170726
title:
  T-, B- and NK-lymphoid, but not myeloid cells arise from human CD34(+)CD38(-)CD7(+) common lymphoid progenitors expressing lymphoid-specific genes.


PMID: 17178841
DOI: 17178841
title:
  Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.


PMID: 17178890
DOI: 17178890
title:
  A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells.


PMID: 17195838
DOI: 17195838
title:
  A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.


PMID: 17200670
DOI: 17200670
title:
  Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer.


PMID: 17202382
DOI: 17202382
title:
  IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.


PMID: 17210681
DOI: 17210681
title:
  Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.


PMID: 17210682
DOI: 17210682
title:
  Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas.


PMID: 17210693
DOI: 17210693
title:
  Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment.


PMID: 17210724
DOI: 17210724
title:
  Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding of retinoblastoma.


PMID: 17211412
DOI: 17211412
title:
  A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.


PMID: 17213807
DOI: 17213807
title:
  Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.


PMID: 17213808
DOI: 17213808
title:
  HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells.


PMID: 17213809
DOI: 17213809
title:
  Identification and functional signature of genes regulated by structurally different ABL kinase inhibitors.


PMID: 17213814
DOI: 17213814
title:
  Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells.


PMID: 17220891
DOI: 17220891
title:
  The quantitative trait gene latexin influences the size of the hematopoietic stem cell population in mice.


PMID: 17220892
DOI: 17220892
title:
  Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.


PMID: 17222789
DOI: 17222789
title:
  A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.


PMID: 17234770
DOI: 17234770
title:
  Suppression of mammary carcinoma cell growth by retinoic acid: the cell cycle control gene Btg2 is a direct target for retinoic acid receptor signaling.


PMID: 17234778
DOI: 17234778
title:
  Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.


PMID: 17234781
DOI: 17234781
title:
  2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells.


PMID: 17234794
DOI: 17234794
title:
  Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer.


PMID: 17237394
DOI: 17237394
title:
  Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals.


PMID: 17237808
DOI: 17237808
title:
  Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells.


PMID: 17252012
DOI: 17252012
title:
  Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase.


PMID: 17252022
DOI: 17252022
title:
  Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals.


PMID: 17255260
DOI: 17255260
title:
  Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray.


PMID: 17260014
DOI: 17260014
title:
  Identification of a metastasis signature and the DLX4 homeobox protein as a regulator of metastasis by combined transcriptome approach.


PMID: 17260020
DOI: 17260020
title:
  Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.


PMID: 17283122
DOI: 17283122
title:
  TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition.


PMID: 17287849
DOI: 17287849
title:
  Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin.


PMID: 17287851
DOI: 17287851
title:
  HTLV-I infection of WE17/10 CD4+ cell line leads to progressive alteration of Ca2+ influx that eventually results in loss of CD7 expression and activation of an antiapoptotic pathway involving AKT and BAD which paves the way for malignant transformation.


PMID: 17289871
DOI: 17289871
title:
  Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues.


PMID: 17297437
DOI: 17297437
title:
  ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes.


PMID: 17297452
DOI: 17297452
title:
  Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.


PMID: 17297461
DOI: 17297461
title:
  Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.


PMID: 17297473
DOI: 17297473
title:
  Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis.


PMID: 17308078
DOI: 17308078
title:
  The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.


PMID: 17308109
DOI: 17308109
title:
  Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.


PMID: 17308118
DOI: 17308118
title:
  Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma.


PMID: 17308126
DOI: 17308126
title:
  Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion.


PMID: 17325667
DOI: 17325667
title:
  A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors.


PMID: 17330098
DOI: 17330098
title:
  Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.


PMID: 17332353
DOI: 17332353
title:
  Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection.


PMID: 17334365
DOI: 17334365
title:
  Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome.


PMID: 17334389
DOI: 17334389
title:
  Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis.


PMID: 17349694
DOI: 17349694
title:
  Transcriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccination.


PMID: 17353439
DOI: 17353439
title:
  Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease.


PMID: 17363560
DOI: 17363560
title:
  Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis.


PMID: 17363561
DOI: 17363561
title:
  Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late-stage differentiation of normal B cells.


PMID: 17363581
DOI: 17363581
title:
  Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia.


PMID: 17371845
DOI: 17371845
title:
  Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice.


PMID: 17389037
DOI: 17389037
title:
  Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis.


PMID: 17403900
DOI: 17403900
title:
  Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.


PMID: 17404570
DOI: 17404570
title:
  p53 and Delta Np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, DNA repair and apoptosis.


PMID: 17404577
DOI: 17404577
title:
  Id3 is a novel regulator of p27kip1 mRNA in early G1 phase and is required for cell-cycle progression.


PMID: 17406368
DOI: 17406368
title:
  Poorly differentiated and anaplastic thyroid carcinomas: chromosomal and oligo-array profile of five new cell lines.


PMID: 17409405
DOI: 17409405
title:
  Isogenic normal basal and luminal mammary epithelial isolated by a novel method show a differential response to ionizing radiation.


PMID: 17409432
DOI: 17409432
title:
  Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.


PMID: 17409441
DOI: 17409441
title:
  Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).


PMID: 17409444
DOI: 17409444
title:
  Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin.


PMID: 17409456
DOI: 17409456
title:
  A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis.


PMID: 17420266
DOI: 17420266
title:
  Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors.


PMID: 17430594
DOI: 17430594
title:
  Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process.


PMID: 17438126
DOI: 17438126
title:
  NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes.


PMID: 17438134
DOI: 17438134
title:
  Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6.


PMID: 17438526
DOI: 17438526
title:
  Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.


PMID: 17440055
DOI: 17440055
title:
  Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors.


PMID: 17440068
DOI: 17440068
title:
  TIP30 mutant derived from hepatocellular carcinoma specimens promotes growth of HepG2 cells through up-regulation of N-cadherin.


PMID: 17440070
DOI: 17440070
title:
  Cancer cell lines as genetic models of their parent histology: analyses based on array comparative genomic hybridization.


PMID: 17440082
DOI: 17440082
title:
  Synergistic effect of cyclin D1 and c-Myc leads to more aggressive and invasive mammary tumors in severe combined immunodeficient mice.


PMID: 17440099
DOI: 17440099
title:
  Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.


PMID: 17440110
DOI: 17440110
title:
  Aromatase localization in human breast cancer tissues: possible interactions between intratumoral stromal and parenchymal cells.


PMID: 17452977
DOI: 17452977
title:
  The LIM-only factor LMO4 regulates expression of the BMP7 gene through an HDAC2-dependent mechanism, and controls cell proliferation and apoptosis of mammary epithelial cells.


PMID: 17452985
DOI: 17452985
title:
  Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune function.


PMID: 17456585
DOI: 17456585
title:
  LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.


PMID: 17464315
DOI: 17464315
title:
  Gene expression analysis of soft tissue sarcomas: characterization and reclassification of malignant fibrous histiocytoma.


PMID: 17468756
DOI: 17468756
title:
  MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.


PMID: 17470548
DOI: 17470548
title:
  Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes.


PMID: 17483311
DOI: 17483311
title:
  CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.


PMID: 17483315
DOI: 17483315
title:
  Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.


PMID: 17483317
DOI: 17483317
title:
  A transgenic mouse model of plasma cell malignancy shows phenotypic, cytogenetic, and gene expression heterogeneity similar to human multiple myeloma.


PMID: 17483325
DOI: 17483325
title:
  Phosphoinositide-3-kinase signaling controls S-phase kinase-associated protein 2 transcription via E2F1 in pancreatic ductal adenocarcinoma cells.


PMID: 17483333
DOI: 17483333
title:
  Reduced PDEF expression increases invasion and expression of mesenchymal genes in prostate cancer cells.


PMID: 17483347
DOI: 17483347
title:
  Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.


PMID: 17483357
DOI: 17483357
title:
  Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.


PMID: 17486063
DOI: 17486063
title:
  The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.


PMID: 17486072
DOI: 17486072
title:
  Epstein-Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFbeta signaling pathways.


PMID: 17486082
DOI: 17486082
title:
  ERalpha-CITED1 co-regulated genes expressed during pubertal mammary gland development: implications for breast cancer prognosis.


PMID: 17486088
DOI: 17486088
title:
  Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment.


PMID: 17496896
DOI: 17496896
title:
  Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.


PMID: 17502666
DOI: 17502666
title:
  Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program.


PMID: 17510386
DOI: 17510386
title:
  Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers.


PMID: 17525748
DOI: 17525748
title:
  Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.


PMID: 17525749
DOI: 17525749
title:
  Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.


PMID: 17533364
DOI: 17533364
title:
  Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data.


PMID: 17533371
DOI: 17533371
title:
  Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.


PMID: 17540585
DOI: 17540585
title:
  Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.


PMID: 17548472
DOI: 17548472
title:
  The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner.


PMID: 17560996
DOI: 17560996
title:
  Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines.


PMID: 17562867
DOI: 17562867
title:
  Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.


PMID: 17597811
DOI: 17597811
title:
  Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias.


PMID: 17599052
DOI: 17599052
title:
  PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.


PMID: 17603561
DOI: 17603561
title:
  Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition.


PMID: 17621274
DOI: 17621274
title:
  A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release.


PMID: 17623797
DOI: 17623797
title:
  Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide.


PMID: 17636019
DOI: 17636019
title:
  Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5.


PMID: 17638893
DOI: 17638893
title:
  Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors.


PMID: 17651872
DOI: 17651872
title:
  Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections.


PMID: 17667943
DOI: 17667943
title:
  Expression and sequence analysis of candidates for the 1p36.31 tumor suppressor gene deleted in neuroblastomas.


PMID: 17694077
DOI: 17694077
title:
  Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.


PMID: 17700529
DOI: 17700529
title:
  A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells.


PMID: 17704799
DOI: 17704799
title:
  The ternary complex factor Net/Elk-3 participates in the transcriptional response to hypoxia and regulates HIF-1 alpha.


PMID: 17704800
DOI: 17704800
title:
  An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II.


PMID: 17709385
DOI: 17709385
title:
  Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes.


PMID: 17713554
DOI: 17713554
title:
  Combined single nucleotide polymorphism-based genomic mapping and global gene expression profiling identifies novel chromosomal imbalances, mechanisms and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with inv(14)(q11q32).


PMID: 17717066
DOI: 17717066
title:
  Transcriptional analysis of quiescent and proliferating CD34+ human hemopoietic cells from normal and chronic myeloid leukemia sources.


PMID: 17723218
DOI: 17723218
title:
  Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.


PMID: 17726467
DOI: 17726467
title:
  PLD1 is overexpressed in an ER-negative MCF-7 cell line variant and a subset of phospho-Akt-negative breast carcinomas.


PMID: 17728400
DOI: 17728400
title:
  Transcriptome-wide analysis of blood vessels laser captured from human skin and chronic wound-edge tissue.


PMID: 17761290
DOI: 17761290
title:
  Hematopoietic stem cell mobilization with G-CSF induces innate inflammation yet suppresses adaptive immune gene expression as revealed by microarray analysis.


PMID: 17761758
DOI: 17761758
title:
  Isolation and characterization of mesoangioblasts from facioscapulohumeral muscular dystrophy muscle biopsies.


PMID: 17767167
DOI: 17767167
title:
  Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.


PMID: 17873879
DOI: 17873879
title:
  Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses.


PMID: 17873908
DOI: 17873908
title:
  Molecular profiling related to poor prognosis in thyroid carcinoma. Combining gene expression data and biological information.


PMID: 17873912
DOI: 17873912
title:
  Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling.


PMID: 17878328
DOI: 17878328
title:
  Natural phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest a role for CD5 in malignant phenotype.


PMID: 17890238
DOI: 17890238
title:
  Neutrality, compensation, and negative selection during evolution of B-cell development transcriptomes.


PMID: 17898786
DOI: 17898786
title:
  Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia.


PMID: 17906636
DOI: 17906636
title:
  Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.


PMID: 17908789
DOI: 17908789
title:
  Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets.


PMID: 17922013
DOI: 17922013
title:
  Ancestral reconstruction of segmental duplications reveals punctuated cores of human genome evolution.


PMID: 17932948
DOI: 17932948
title:
  Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis.


PMID: 17934524
DOI: 17934524
title:
  An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia.


PMID: 17952124
DOI: 17952124
title:
  Array CGH and gene-expression profiling reveals distinct genomic instability patterns associated with DNA repair and cell-cycle checkpoint pathways in Ewing's sarcoma.


PMID: 17954559
DOI: 17954559
title:
  Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes.


PMID: 17967875
DOI: 17967875
title:
  Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.


PMID: 17968324
DOI: 17968324
title:
  Microarray analysis refines classification of non-medullary thyroid tumours of uncertain malignancy.


PMID: 17971902
DOI: 17971902
title:
  Characterization of ovarian cancer ascites on cell invasion, proliferation, spheroid formation, and gene expression in an in vitro model of epithelial ovarian cancer.


PMID: 17975138
DOI: 17975138
title:
  Identification and validation of a novel gene signature associated with the recurrence of human hepatocellular carcinoma.


PMID: 17998334
DOI: 17998334
title:
  Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation.


PMID: 17998939
DOI: 17998939
title:
  Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice.


PMID: 18003728
DOI: 18003728
title:
  Transcriptome analysis of NF-kappaB- and phosphatidylinositol 3-kinase-regulated genes in human cytomegalovirus-infected monocytes.


PMID: 18006812
DOI: 18006812
title:
  Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation.


PMID: 18024188
DOI: 18024188
title:
  Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.


PMID: 18025126
DOI: 18025126
title:
  Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.


PMID: 18025162
DOI: 18025162
title:
  Cutting edge: A transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway.


PMID: 18025183
DOI: 18025183
title:
  Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9.


PMID: 18025224
DOI: 18025224
title:
  Identification of signaling pathways in macrophage exposed to Porphyromonas gingivalis or to its purified cell wall components.


PMID: 18026104
DOI: 18026104
title:
  Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.


PMID: 18026132
DOI: 18026132
title:
  Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk.


PMID: 18029397
DOI: 18029397
title:
  Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide.


PMID: 18037878
DOI: 18037878
title:
  Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells.


PMID: 18037961
DOI: 18037961
title:
  Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.


PMID: 18070364
DOI: 18070364
title:
  Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer.


PMID: 18071306
DOI: 18071306
title:
  Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia.


PMID: 18081042
DOI: 18081042
title:
  The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells.


PMID: 18157142
DOI: 18157142
title:
  Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.


PMID: 18171944
DOI: 18171944
title:
  A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function.


PMID: 18172295
DOI: 18172295
title:
  Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.


PMID: 18176567
DOI: 18176567
title:
  Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.


PMID: 18195040
DOI: 18195040
title:
  The absence of Ser389 phosphorylation in p53 affects the basal gene expression level of many p53-dependent genes and alters the biphasic response to UV exposure in mouse embryonic fibroblasts.


PMID: 18199539
DOI: 18199539
title:
  Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling.


PMID: 18212050
DOI: 18212050
title:
  Inducible expression of chimeric EWS/ETS proteins confers Ewing's family tumor-like phenotypes to human mesenchymal progenitor cells.


PMID: 18223687
DOI: 18223687
title:
  Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins.


PMID: 18245461
DOI: 18245461
title:
  Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility.


PMID: 18245467
DOI: 18245467
title:
  Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors.


PMID: 18245484
DOI: 18245484
title:
  Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function.


PMID: 18245496
DOI: 18245496
title:
  Tumor immunobiological differences in prostate cancer between African-American and European-American men.


PMID: 18270326
DOI: 18270326
title:
  Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound.


PMID: 18275831
DOI: 18275831
title:
  Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity.


PMID: 18280186
DOI: 18280186
title:
  Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.


PMID: 18281482
DOI: 18281482
title:
  Efficient identification of a novel cancer/testis antigen for immunotherapy using three-step microarray analysis.


PMID: 18281483
DOI: 18281483
title:
  Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell lymphoma cells.


PMID: 18281487
DOI: 18281487
title:
  Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.


PMID: 18285459
DOI: 18285459
title:
  The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.


PMID: 18285465
DOI: 18285465
title:
  DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.


PMID: 18292557
DOI: 18292557
title:
  Airway epithelial versus immune cell Stat1 function for innate defense against respiratory viral infection.


PMID: 18292579
DOI: 18292579
title:
  Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.


PMID: 18310327
DOI: 18310327
title:
  HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype.


PMID: 18313334
DOI: 18313334
title:
  TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.


PMID: 18316590
DOI: 18316590
title:
  Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome.


PMID: 18316609
DOI: 18316609
title:
  EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma.


PMID: 18316615
DOI: 18316615
title:
  Expression of HER2 and estrogen receptor alpha depends upon nuclear localization of Y-box binding protein-1 in human breast cancers.


PMID: 18317448
DOI: 18317448
title:
  Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.


PMID: 18332864
DOI: 18332864
title:
  Identification of unique and common low abundance tumour-specific transcripts by suppression subtractive hybridization and oligonucleotide probe array analysis.


PMID: 18339843
DOI: 18339843
title:
  Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer.


PMID: 18339860
DOI: 18339860
title:
  Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis.


PMID: 18339861
DOI: 18339861
title:
  Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment.


PMID: 18345002
DOI: 18345002
title:
  TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes.


PMID: 18378698
DOI: 18378698
title:
  Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking.


PMID: 18381411
DOI: 18381411
title:
  Bisphenol A induces a profile of tumor aggressiveness in high-risk cells from breast cancer patients.


PMID: 18381418
DOI: 18381418
title:
  Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer.


PMID: 18381423
DOI: 18381423
title:
  EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.


PMID: 18381431
DOI: 18381431
title:
  Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.


PMID: 18381438
DOI: 18381438
title:
  The cyclin-dependent kinase inhibitor flavopiridol potentiates the effects of topoisomerase I poisons by suppressing Rad51 expression in a p53-dependent manner.


PMID: 18381450
DOI: 18381450
title:
  MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1.


PMID: 18381945
DOI: 18381945
title:
  Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma.


PMID: 18413723
DOI: 18413723
title:
  A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.


PMID: 18413731
DOI: 18413731
title:
  Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors.


PMID: 18413734
DOI: 18413734
title:
  Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.


PMID: 18413746
DOI: 18413746
title:
  Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.


PMID: 18413748
DOI: 18413748
title:
  Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA.


PMID: 18426912
DOI: 18426912
title:
  Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9.


PMID: 18427549
DOI: 18427549
title:
  Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer.


PMID: 18443585
DOI: 18443585
title:
  An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.


PMID: 18443592
DOI: 18443592
title:
  Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.


PMID: 18451145
DOI: 18451145
title:
  Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence.


PMID: 18451147
DOI: 18451147
title:
  Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma.


PMID: 18451154
DOI: 18451154
title:
  Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.


PMID: 18453574
DOI: 18453574
title:
  Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II.


PMID: 18454173
DOI: 18454173
title:
  JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells.


PMID: 18469815
DOI: 18469815
title:
  Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.


PMID: 18483247
DOI: 18483247
title:
  Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.


PMID: 18488029
DOI: 18488029
title:
  Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.


PMID: 18498781
DOI: 18498781
title:
  Identification of interleukin-1 and interleukin-6-responsive genes in human monocyte-derived macrophages using microarrays.


PMID: 18504433
DOI: 18504433
title:
  Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma.


PMID: 18506891
DOI: 18506891
title:
  Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer.


PMID: 18519671
DOI: 18519671
title:
  Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.


PMID: 18542059
DOI: 18542059
title:
  Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice.


PMID: 18542061
DOI: 18542061
title:
  Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo.


PMID: 18544741
DOI: 18544741
title:
  KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment.


PMID: 18559539
DOI: 18559539
title:
  Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor.


PMID: 18560354
DOI: 18560354
title:
  Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival.


PMID: 18566367
DOI: 18566367
title:
  Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities.


PMID: 18591936
DOI: 18591936
title:
  DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells.


PMID: 18593902
DOI: 18593902
title:
  15-Hydroxyprostaglandin dehydrogenase is a target of hepatocyte nuclear factor 3beta and a tumor suppressor in lung cancer.


PMID: 18599325
DOI: 18599325
title:
  Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages.


PMID: 18625718
DOI: 18625718
title:
  Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex.


PMID: 18632613
DOI: 18632613
title:
  Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells.


PMID: 18632634
DOI: 18632634
title:
  Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand.


PMID: 18641660
DOI: 18641660
title:
  Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.


PMID: 18660816
DOI: 18660816
title:
  Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.


PMID: 18676865
DOI: 18676865
title:
  Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer.


PMID: 18676871
DOI: 18676871
title:
  Carcinogen-altered genes in rat esophagus positively modulated to normal levels of expression by both black raspberries and phenylethyl isothiocyanate.


PMID: 18679425
DOI: 18679425
title:
  Prediction of future metastasis and molecular characterization of head and neck squamous-cell carcinoma based on transcriptome and genome analysis by microarrays.


PMID: 18701482
DOI: 18701482
title:
  Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations.


PMID: 18701491
DOI: 18701491
title:
  CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells.


PMID: 18701887
DOI: 18701887
title:
  T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.


PMID: 18710942
DOI: 18710942
title:
  Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation.


PMID: 18724390
DOI: 18724390
title:
  Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration.


PMID: 18757430
DOI: 18757430
title:
  LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.


PMID: 18757432
DOI: 18757432
title:
  Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer.


PMID: 18757440
DOI: 18757440
title:
  Identification of secreted proteins that mediate cell-cell interactions in an in vitro model of the lung cancer microenvironment.


PMID: 18762803
DOI: 18762803
title:
  Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.


PMID: 18762810
DOI: 18762810
title:
  In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.


PMID: 18794111
DOI: 18794111
title:
  Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.


PMID: 18794119
DOI: 18794119
title:
  CYR61 and alphaVbeta5 integrin cooperate to promote invasion and metastasis of tumors growing in preirradiated stroma.


PMID: 18794130
DOI: 18794130
title:
  P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response.


PMID: 18794137
DOI: 18794137
title:
  Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts.


PMID: 18794802
DOI: 18794802
title:
  Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer.


PMID: 18802101
DOI: 18802101
title:
  Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms.


PMID: 18806801
DOI: 18806801
title:
  Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development.


PMID: 18829530
DOI: 18829530
title:
  Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.


PMID: 18829555
DOI: 18829555
title:
  RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.


PMID: 18829567
DOI: 18829567
title:
  Presentation of telomerase reverse transcriptase, a self-tumor antigen, is down-regulated by histone deacetylase inhibition.


PMID: 18838534
DOI: 18838534
title:
  Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.


PMID: 18838536
DOI: 18838536
title:
  AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.


PMID: 18838539
DOI: 18838539
title:
  Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor.


PMID: 18852285
DOI: 18852285
title:
  Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2.


PMID: 18854153
DOI: 18854153
title:
  Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development.


PMID: 18922927
DOI: 18922927
title:
  Utilization of pathway signatures to reveal distinct types of B lymphoma in the Emicro-myc model and human diffuse large B-cell lymphoma.


PMID: 18955504
DOI: 18955504
title:
  Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.


PMID: 18974123
DOI: 18974123
title:
  Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer.


PMID: 18974140
DOI: 18974140
title:
  DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity.


PMID: 18981216
DOI: 18981216
title:
  Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen.


PMID: 18981221
DOI: 18981221
title:
  Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the biosynthesis of retinoic acid: generation and characterization of a knockout mouse.


PMID: 19010892
DOI: 19010892
title:
  NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas.


PMID: 19010895
DOI: 19010895
title:
  MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.


PMID: 19010928
DOI: 19010928
title:
  IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model.


PMID: 19023113
DOI: 19023113
title:
  Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.


PMID: 19029983
DOI: 19029983
title:
  Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis.


PMID: 19047146
DOI: 19047146
title:
  SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cells.


PMID: 19047182
DOI: 19047182
title:
  Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.


PMID: 19061838
DOI: 19061838
title:
  Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer.


PMID: 19074878
DOI: 19074878
title:
  The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?


PMID: 19074894
DOI: 19074894
title:
  Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells.


PMID: 19074895
DOI: 19074895
title:
  Common transcriptional signature of tumor-infiltrating mononuclear inflammatory cells and peripheral blood mononuclear cells in hepatocellular carcinoma patients.


PMID: 19074901
DOI: 19074901
title:
  A mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas.


PMID: 19075290
DOI: 19075290
title:
  Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection.


PMID: 19108712
DOI: 19108712
title:
  Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: synchronous and differential responses.


PMID: 19124732
DOI: 19124732
title:
  Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells.


PMID: 19139170
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DOI: 19144320
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DOI: 19155521
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DOI: 19158274
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DOI: 19158679
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DOI: 19185518
title:
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DOI: 19188439
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title:
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DOI: 19201883
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DOI: 19234201
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DOI: 19265172
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DOI: 19270711
title:
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PMID: 19273610
DOI: 19273610
title:
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DOI: 19289500
title:
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PMID: 19289501
DOI: 19289501
title:
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DOI: 19307312
title:
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DOI: 19332562
title:
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DOI: 19345118
title:
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DOI: 19412182
title:
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DOI: 19414603
title:
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DOI: 19414752
title:
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DOI: 19451226
title:
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DOI: 19451229
title:
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DOI: 19454677
title:
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DOI: 19464196
title:
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DOI: 19477428
title:
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DOI: 19490892
title:
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DOI: 19494283
title:
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DOI: 19503106
title:
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DOI: 19564408
title:
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DOI: 19568420
title:
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DOI: 19580510
title:
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PMID: 19581626
DOI: 19581626
title:
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DOI: 19592655
title:
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DOI: 19596788
title:
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PMID: 19608860
DOI: 19608860
title:
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DOI: 19633656
title:
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PMID: 19687298
DOI: 19687298
title:
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PMID: 19703992
DOI: 19703992
title:
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DOI: 19723656
title:
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DOI: 19752192
title:
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DOI: 19800266
title:
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DOI: 19805141
title:
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DOI: 19805515
title:
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DOI: 19805517
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DOI: 19832978
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DOI: 19858293
title:
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DOI: 19884340
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DOI: 22772404
title:
  The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.


PMID: 22786769
DOI: 22786769
title:
  IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells.


PMID: 22802645
DOI: 22802645
title:
  Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages.


PMID: 22855714
DOI: 22855714
title:
  Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity.


PMID: 22941246
DOI: 22941246
title:
  Lymphoid priming in human bone marrow begins before expression of CD10 with upregulation of L-selectin.


PMID: 22949304
DOI: 22949304
title:
  High-dimensional gene expression profiling studies in high and low responders to primary smallpox vaccination.


PMID: 22966001
DOI: 22966001
title:
  Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.


PMID: 22968462
DOI: 22968462
title:
  Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function.


PMID: 22974541
DOI: 22974541
title:
  Development and validation of a new in vitro assay designed to measure contact allergen-triggered oxidative stress in dendritic cells.


PMID: 22986450
DOI: 22986450
title:
  Francisella tularensis alters human neutrophil gene expression: insights into the molecular basis of delayed neutrophil apoptosis.


PMID: 22991471
DOI: 22991471
title:
  Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells.


PMID: 23018461
DOI: 23018461
title:
  Transient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8+ T effector-memory cells.


PMID: 23027924
DOI: 23027924
title:
  Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.


PMID: 23067362
DOI: 23067362
title:
  The blood transcriptional signature of chronic hepatitis C virus is consistent with an ongoing interferon-mediated antiviral response.


PMID: 23084923
DOI: 23084923
title:
  Differential responses of immune cells to type I interferon contribute to host resistance to viral infection.


PMID: 23103132
DOI: 23103132
title:
  The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy.


PMID: 23125413
DOI: 23125413
title:
  IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy.


PMID: 23142781
DOI: 23142781
title:
  Nucleic acid-sensing Toll-like receptors are essential for the control of endogenous retrovirus viremia and ERV-induced tumors.


PMID: 23151505
DOI: 23151505
title:
  Merck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity.


PMID: 23159438
DOI: 23159438
title:
  Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.


PMID: 23209417
DOI: 23209417
title:
  Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.


PMID: 23293084
DOI: 23293084
title:
  Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.


PMID: 23305731
DOI: 23305731
title:
  Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells.


PMID: 23325888
DOI: 23325888
title:
  Id2 influences differentiation of killer cell lectin-like receptor G1(hi) short-lived CD8+ effector T cells.


PMID: 23420886
DOI: 23420886
title:
  Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.


PMID: 23444399
DOI: 23444399
title:
  Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity.


PMID: 23527130
DOI: 23527130
title:
  Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.


PMID: 23535375
DOI: 23535375
title:
  Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties.


PMID: 23548837
DOI: 23548837
title:
  Egr2-dependent gene expression profiling and ChIP-Seq reveal novel biologic targets in T cell anergy.


PMID: 23583644
DOI: 23583644
title:
  Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.


PMID: 23592216
DOI: 23592216
title:
  Suppression of the LMP2A target gene, EGR-1, protects Hodgkin's lymphoma cells from entry to the EBV lytic cycle.


PMID: 23636981
DOI: 23636981
title:
  Interferon-beta therapy in multiple sclerosis: the short-term and long-term effects on the patients' individual gene expression in peripheral blood.


PMID: 23658707
DOI: 23658707
title:
  Genome-wide characterization of transcriptional patterns in high and low antibody responders to rubella vaccination.


PMID: 23759749
DOI: 23759749
title:
  Cytokine and gene transcription profiles of immune responses elicited by HIV lipopeptide vaccine in HIV-negative volunteers.


PMID: 23844129
DOI: 23844129
title:
  Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A.


PMID: 24336226
DOI: 24336226
title:
  Molecular signatures of antibody responses derived from a systems biology study of five human vaccines.


PMID: 24495909
DOI: 24495909
title:
  Differences in antibody responses between trivalent inactivated influenza vaccine and live attenuated influenza vaccine correlate with the kinetics and magnitude of interferon signaling in children.


PMID: 24808365
DOI: 24808365
title:
  Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction.


PMID: 24833394
DOI: 24833394
title:
  Positive feedback within a kinase signaling complex functions as a switch mechanism for NF-κB activation.


PMID: 24912498
DOI: 24912498
title:
  Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.


PMID: 25037231
DOI: 25037231
title:
  Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.


PMID: 25596819
DOI: 25596819
title:
  Aging-dependent alterations in gene expression and a mitochondrial signature of responsiveness to human influenza vaccination.


PMID: 25681390
DOI: 25681390
title:
  Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development.


PMID: 25706537
DOI: 25706537
title:
  A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination.


PMID: 26148331
DOI: 26148331
title:
  The expression of B & T cell activation markers in children's tonsils following live attenuated influenza vaccine.


PMID: 26405566
DOI: 26405566
title:
  BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.


PMID: 26637961
DOI: 26637961
title:
  A shortened interval between vaccinations with the trivalent inactivated influenza vaccine increases responsiveness in the aged.


PMID: 26726811
DOI: 26726811
title:
  Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events.


PMID: 26742691
DOI: 26742691
title:
  Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination.


PMID: 26755593
DOI: 26755593
title:
  Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood.


PMID: 26763932
DOI: 26763932
title:
  Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry.


PMID: 27030598
DOI: 27030598
title:
  Diversification of the antigen-specific T cell receptor repertoire after varicella zoster vaccination.


PMID: 27191501
DOI: 27191501
title:
  De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.


PMID: 27280975
DOI: 27280975
title:
  Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.


PMID: 27317456
DOI: 27317456
title:
  Transcriptional signatures of influenza A/H1N1-specific IgG memory-like B cell response in older individuals.


PMID: 27322481
DOI: 27322481
title:
  Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial.


PMID: 27529750
DOI: 27529750
title:
  Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination.


PMID: 27534615
DOI: 27534615
title:
  Gene signatures associated with adaptive humoral immunity following seasonal influenza A/H1N1 vaccination.


PMID: 27870591
DOI: 27870591
title:
  Human transcriptome response to immunization with live-attenuated Venezuelan equine encephalitis virus vaccine (TC-83): Analysis of whole blood.


PMID: 28099485
DOI: 28099485
title:
  Cell-Based Systems Biology Analysis of Human AS03-Adjuvanted H5N1 Avian Influenza Vaccine Responses: A Phase I Randomized Controlled Trial.


PMID: 28137280
DOI: 28137280
title:
  High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.


PMID: 28498607
DOI: 28498607
title:
  Human hepatocellular carcinomas with a periportal phenotype have the lowest potential for early recurrence after curative resection.


PMID: 28498840
DOI: 28498840
title:
  A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH.


PMID: 28549970
DOI: 28549970
title:
  Distinct patterns of cellular immune response elicited by influenza non-adjuvanted and AS03-adjuvanted monovalent H1N1(pdm09) vaccine.


PMID: 28842433
DOI: 28842433
title:
  Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses.


PMID: 28847964
DOI: 28847964
title:
  Global metabolic reprogramming of colorectal cancer
  					occurs at adenoma stage and is induced by MYC.


PMID: 28853442
DOI: 28853442
title:
  PO and ID BCG vaccination in humans induce distinct mucosal and systemic immune responses and CD4+ T cell transcriptomal molecular signatures.


PMID: 28854372
DOI: 28854372
title:
  Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.


PMID: 28855211
DOI: 28855211
title:
  The Blebbishield Emergency Program Overrides Chromosomal Instability and Phagocytosis Checkpoints in Cancer Stem Cells.


PMID: 29132989
DOI: 29132989
title:
  Differential gene expression elicited by children in response to the 2015-16 live attenuated versus inactivated influenza vaccine.


PMID: 29580160
DOI: 29580160
title:
  Significant transcriptome and cytokine changes in hepatitis B vaccine non-responders revealed by genome-wide comparative analysis.


PMID: 29802404
DOI: 29802404
title:
  Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing.


PMID: 29868000
DOI: 29868000
title:
  Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults.


PMID: 30166318
DOI: 30166318
title:
  Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney.


PMID: 30247603
DOI: 30247603
title:
  Impact of Zostavax Vaccination on T-Cell Accumulation and Cutaneous Gene Expression in the Skin of Older Humans After Varicella Zoster Virus Antigen-Specific Challenge.


PMID: 30553813
DOI: 30553813
title:
  CellMinerCDB for Integrative Cross-Database Genomics
  					and Pharmacogenomics Analyses of Cancer Cell Lines.


PMID: 30566602
DOI: 30566602
title:
  AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells.


PMID: 30837223
DOI: 30837223
title:
  Retrodifferentiation of Human Tumor Hepatocytes to
  					Stem Cells Leads to Metabolic Reprogramming and Chemoresistance.


PMID: 31004097
DOI: 31004097
title:
  Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts.


PMID: 31088844
DOI: 31088844
title:
  A Gene Signature Predicting Natural Killer Cell
  					Infiltration and Improved Survival in Melanoma Patients.


PMID: 31249312
DOI: 31249312
title:
  A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys.


PMID: 31269016
DOI: 31269016
title:
  Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis.


PMID: 32019869
DOI: 32019869
title:
  Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches.


PMID: 32109414
DOI: 32109414
title:
  Caloric Restriction Reprograms the Single-Cell
  					Transcriptional Landscape of Rattus Norvegicus Aging.


PMID: 32240714
DOI: 32240714
title:
  Epigenetic footprint enables molecular risk
  					stratification of hepatoblastoma with clinical implications.


PMID: 32663312
DOI: 32663312
title:
  HRT Atlas v1.0 database: redefining human and mouse
  					housekeeping genes and candidate reference transcripts by mining
  					massive RNA-seq datasets.


PMID: 33429950
DOI: 33429950
title:
  Whole Transcription Profile of Responders to Anti-TNF Drugs in Pediatric Inflammatory Bowel Disease.


PMID: 33458693
DOI: 33458693
title:
  Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.


PMID: 33691112
DOI: 33691112
title:
  Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution.


PMID: 33766982
DOI: 33766982
title:
  WWTR1
  					(TAZ)-
  					CAMTA1
  					gene fusion is sufficient to dysregulate YAP/TAZ signaling and
  					drive epithelioid hemangioendothelioma tumorigenesis.
  				


PMID: 34885022
DOI: 34885022
title:
  MiRNA Deregulation Distinguishes Anaplastic Thyroid
  					Carcinoma (ATC) and Supports Upregulation of Oncogene Expression.


PMID: 35477723
DOI: 35477723
title:
  ASCL1 activates neuronal stem cell-like lineage
  					programming through remodeling of the chromatin landscape in
  					prostate cancer.


PMID: 35974106
DOI: 35974106
title:
  A new gene set identifies senescent cells and predicts
  					senescence-associated pathways across tissues.


PMID: 36123353
DOI: 36123353
title:
  Integrated stem cell signature and cytomolecular risk
  					determination in pediatric acute myeloid leukemia.


PMID: 36493756
DOI: 36493756
title:
  A human fetal lung cell atlas uncovers proximal-distal
  					gradients of differentiation and key regulators of epithelial
  					fates.


PMID: 37272757
DOI: 37272757
title:
  The EstroGene Database Reveals Diverse Temporal,
  					Context-Dependent, and Bidirectional Estrogen Receptor Regulomes in
  					Breast Cancer.


PMID: 37636077
DOI: 37636077
title:
  Gene signature reveals decreased SOX10-dependent
  					transcripts in malignant cells from immune checkpoint
  					inhibitor-resistant cutaneous melanomas.


PMID: 38455971
DOI: 38455971
title:
  Tissue-resident memory T cell signatures from
  					single-cell analysis associated with better melanoma prognosis.


PMID: 38578993
DOI: 38578993
title:
  Cellular atlas of the human ovary using
  					morphologically guided spatial transcriptomics and single-cell
  					sequencing.


PMID: 9826724
DOI: 9826724
title:
  Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays.


PMID: 9861020
DOI: 9861020
title:
  Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays.


# external_term

term: R-HSA-179419
external_name:
  APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint


term: R-HSA-5693565
external_name:
  Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks


term: R-HSA-9704331
external_name:
  Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function


term: R-HSA-9704646
external_name:
  Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function


term: R-HSA-159763
external_name:
  Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus


term: GO:0000467
external_name:
  exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


term: GO:0002486
external_name:
  antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent


term: GO:0002822
external_name:
  regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains


term: GO:0002823
external_name:
  negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains


term: GO:0002824
external_name:
  positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains


term: GO:0006978
external_name:
  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator


term: GO:0016702
external_name:
  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen


term: GO:1902166
external_name:
  negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator


term: GO:1904315
external_name:
  transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential


term: GO:1905930
external_name:
  regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching


