Description

This is an assembly hub for Zaire ebolavirus.

There are two strains:

• Mayinga strain, NC002549, 1976.
• An inferred most recent common ancestor for the 2014 outbreak

There are alignments to other sequences in both species Ebola and genus ebolavirus, with various subsets.

Methods

Genome and gene annotations were computed from the data at genbank accession NC_002549 version NC_002549.1, GI:10313991.

Since the browser can't handle overlapping exons, the GP1,2 gene was split into two, GP12a and GP12b, which each having a single exon spanning the full length unedited gene, and each having one of the two CDSs.

Following the genbank accession, we use the 1-base-deletion version of ssGP rather than the 2-base-insertion version.

The alignments are from the Gire-2014 supplement. The various subsets were chosen as follows:

genus ebolavirus: all 124 sequences

species Ebola: the subset that are in species Ebola (101 sequences)

2014 Ebola: the subset from the 2014 outbreak (81 sequences)

48 clusters, 25 clusters, and 6 2014 clusters are the sets of sequences in genus ebolavirus, species Ebola, and 2014 Ebola, respectively, except that only one sequence has been included from each of the 3 clusters of 2014 sequences defined in Gire-2014 Figure S8.

References

Gire, S. K., Goba, A., Andersen, K. G., Sealfon, R., & Park, D. J. (2014). Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science (New York, NY).

Credits

Questions should be directed to Irwin Jungreis