ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A01 compound treatment 852873.0 265000.0 0.38 846067.0 238000.0 0.33 0.5017 0.998 2069431 Maybridge1_000177 OCCN1CCN(CC1)c2ncc(Cl)cc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A02 compound treatment 824636.0 237000.0 0.34 833245.0 225000.0 0.31 0.4607 0.9994 1539016 Maybridge1_000178 CCOC(=O)C1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A03 compound treatment 842191.0 255000.0 0.36 862087.0 254000.0 0.35 0.5068 0.9999 2069432 Maybridge1_000179 c1csc(c1)c2cc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A04 compound treatment 838666.0 251000.0 0.36 867953.0 260000.0 0.36 0.509 1.0 1705599 Maybridge1_000180 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A05 compound treatment 844453.0 257000.0 0.37 872084.0 264000.0 0.37 0.5189 1.0 2069433 Maybridge1_000181 [O-][N+](=O)c1cccnc1N2CCCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A06 compound treatment 880370.0 293000.0 0.42 879135.0 271000.0 0.38 0.562 0.9989 1502090 Maybridge1_000182 CCc1cccc(C)c1NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A07 compound treatment 896363.0 309000.0 0.44 892345.0 284000.0 0.4 0.5911 0.9987 2069434 Maybridge1_000183 CC(C)(C)OC(=O)NCCNC(=O)Nc1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A08 compound treatment 888323.0 301000.0 0.43 850814.0 243000.0 0.34 0.542 0.9933 2069435 Maybridge1_000184 CC1CCCC(C)N1C(=S)Nc2ccc(C)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A09 compound treatment 906596.0 319000.0 0.45 899151.0 291000.0 0.41 0.6081 0.9985 2069436 Maybridge1_000185 CC(=O)Nc1cc(ccc1n2cc(C)c(n2)C(F)(F)F)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A10 compound treatment 905602.0 318000.0 0.45 916362.0 308000.0 0.43 0.624 0.9997 1564219 Maybridge1_000186 Cc1ccc(cc1)c2csc3ncnc(N4CCc5ccccc5C4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A11 compound treatment 881929.0 294000.0 0.42 874153.0 266000.0 0.37 0.5586 0.9982 2069437 Maybridge1_000187 [O-][N+](=O)c1ccc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A12 compound treatment 953225.0 366000.0 0.52 921295.0 313000.0 0.44 0.6768 0.9963 1073786 Maybridge1_000188 CCOC(=O)c1c(N)sc2CN(C)CCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A13 compound treatment 902209.0 315000.0 0.45 922005.0 314000.0 0.44 0.6262 0.9999 2069438 Maybridge1_000189 CC(C)(C)c1ccc(cc1)C(=O)NCCNc2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A14 compound treatment 891126.0 304000.0 0.43 904991.0 297000.0 0.41 0.5983 0.9998 2069439 Maybridge1_000190 CC(C)(C)OC(=O)NCCCNC(=S)Nc1ccc2OCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A15 compound treatment 937728.0 350000.0 0.5 904329.0 296000.0 0.41 0.6445 0.9957 1122662 Maybridge1_000191 Clc1ccc(cc1)S(=O)(=O)N2CCCN(Cc3ccc(Cl)cc3Cl)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A16 compound treatment 957004.0 369000.0 0.53 893106.0 285000.0 0.4 0.6528 0.9906 2069440 Maybridge1_000192 CCCCCc1ccc(NC(=O)NNc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A17 compound treatment 930535.0 343000.0 0.49 904592.0 297000.0 0.41 0.6375 0.9967 2069441 Maybridge1_000193 CC(=O)c1ccc(OCC(O)CN2CCCN(CC2)C(=O)c3cccs3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A18 compound treatment 900761.0 313000.0 0.45 864690.0 257000.0 0.36 0.5682 0.9942 1083184 Maybridge1_000194 COc1ccccc1NC(=S)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A19 compound treatment 934869.0 347000.0 0.49 931012.0 323000.0 0.45 0.6679 0.999 1522108 Maybridge1_000195 COc1ccccc1C2CCN(CC2)C(=S)Nc3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A20 compound treatment 916901.0 329000.0 0.47 887041.0 279000.0 0.39 0.6065 0.9958 1083188 Maybridge1_000196 CCOC(=O)c1cc(C)nc2ccc(Br)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A21 compound treatment 906690.0 319000.0 0.45 897388.0 290000.0 0.4 0.6064 0.9983 1170678 Maybridge1_000197 COc1ccc(OCC(O)CNC2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A22 compound treatment 855086.0 268000.0 0.38 854482.0 247000.0 0.34 0.5122 0.9987 1914814 Maybridge1_000198 COc1ccc(/N=C/c2ccccc2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A23 mock treatment 799727.0 212000.0 0.3 876207.0 268000.0 0.37 0.478 0.9943 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 A24 mock treatment 187378.0 -400000.0 -0.57 161268.0 -447000.0 -0.62 -0.8429 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B01 compound treatment 763795.0 176000.0 0.25 807410.0 200000.0 0.28 0.374 0.9986 1118509 Maybridge1_000199 Clc1c(sc2ccccc12)C(=O)N(CCC#N)Cc3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B02 compound treatment 743231.0 156000.0 0.22 837996.0 230000.0 0.32 0.3835 0.9836 2069442 Maybridge1_000200 Clc1c(sc2ccccc12)C(=O)NNC(=S)Nc3cc(Cl)ccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B03 compound treatment 789636.0 202000.0 0.29 879729.0 272000.0 0.38 0.4713 0.9906 2069443 Maybridge1_000201 O=C(N/N=C/c1cccs1)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B04 compound treatment 796147.0 209000.0 0.3 872778.0 265000.0 0.37 0.471 0.9941 2069444 Maybridge1_000202 COc1ccc(cc1)C(=O)NNC(=S)Nc2ccc(Cl)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B05 compound treatment 808580.0 221000.0 0.31 915840.0 308000.0 0.43 0.526 0.9882 2069445 Maybridge1_000203 COc1cc(cc(OC)c1OC)C2SCc3cc(C)c(C)cc3CS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B06 compound treatment 854315.0 267000.0 0.38 904584.0 297000.0 0.41 0.5609 0.9991 2069446 Maybridge1_000204 CC(=O)CS(=O)(=O)c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B07 compound treatment 837190.0 250000.0 0.35 936355.0 328000.0 0.46 0.575 0.992 2069447 Maybridge1_000205 Cc1cccc(Cl)c1/N=C/2\SC(=C)C3(CCCCC3)N2C(=O)c4sc5ccccc5c4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B08 compound treatment 861165.0 274000.0 0.39 887989.0 280000.0 0.39 0.5514 1.0 2069448 Maybridge1_000206 CC(C)CC(C)(SCC(=O)O)SCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B09 compound treatment 898983.0 311000.0 0.44 933722.0 326000.0 0.45 0.6345 0.9999 1559306 Maybridge1_000207 COc1ccc(NC(=S)Nc2c(C)cccc2C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B10 compound treatment 879551.0 292000.0 0.42 916015.0 308000.0 0.43 0.5975 0.9999 2069449 Maybridge1_000208 Cc1cccc2CCCN(C(=S)Nc3cccc(Cl)c3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B11 compound treatment 889353.0 302000.0 0.43 922517.0 315000.0 0.44 0.6138 0.9999 1049127 Maybridge1_000209 CC(=O)Nc1ccc(C)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B12 compound treatment 876772.0 289000.0 0.41 939829.0 332000.0 0.46 0.6182 0.9983 2069450 Maybridge1_000210 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3cccc(c3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B13 compound treatment 907518.0 320000.0 0.46 943667.0 336000.0 0.47 0.6529 0.9999 2069451 Maybridge1_000211 COc1ccc(NC(=O)/C=N/O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B14 compound treatment 878823.0 291000.0 0.41 938969.0 331000.0 0.46 0.6194 0.9985 1083091 Maybridge1_000212 CC(=O)c1cc2cc(Br)ccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B15 compound treatment 911768.0 324000.0 0.46 926837.0 319000.0 0.44 0.6406 0.9998 2069452 Maybridge1_000213 [O-][N+](=O)c1ccc(SCC(=O)Nc2ccc(F)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B16 compound treatment 908610.0 321000.0 0.46 905942.0 298000.0 0.42 0.6168 0.9989 2069453 Maybridge1_000214 CN(C)c1ccc(/C=N/CCC\N=C\c2ccc(cc2)N(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B17 compound treatment 952858.0 365000.0 0.52 944627.0 337000.0 0.47 0.6994 0.9987 1921422 Maybridge1_000215 COc1ccc(/C=N/Cc2ccccc2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B18 compound treatment 865487.0 278000.0 0.4 865603.0 258000.0 0.36 0.5336 0.9989 1017542 Maybridge1_000216 Cc1cc(O)c2ccccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B19 compound treatment 909209.0 322000.0 0.46 947315.0 339000.0 0.47 0.6582 0.9999 2069454 Maybridge1_000217 COc1cc(/N=C/c2ccc3OCOc3c2)c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B20 compound treatment 836566.0 249000.0 0.35 873599.0 266000.0 0.37 0.5125 0.9997 2069455 Maybridge1_000218 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B21 compound treatment 885123.0 298000.0 0.42 905671.0 298000.0 0.42 0.5929 1.0 1721646 Maybridge1_000219 Fc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B22 compound treatment 829837.0 242000.0 0.34 872258.0 264000.0 0.37 0.5044 0.9994 2069456 Maybridge1_000220 COCCCNC(=S)Nc1cccc(Cl)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B23 mock treatment 829075.0 242000.0 0.34 924212.0 316000.0 0.44 0.5548 0.9923 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 B24 mock treatment 144389.0 -443000.0 -0.63 117158.0 -491000.0 -0.68 -0.9296 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C01 compound treatment 737700.0 150000.0 0.21 763259.0 155000.0 0.22 0.3042 1.0 2069457 Maybridge1_000221 OCCN1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C02 compound treatment 723592.0 136000.0 0.19 785128.0 177000.0 0.25 0.3116 0.9926 2069458 Maybridge1_000222 C1CC1Nc2ncnc3scc(c4ccccc4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C03 compound treatment 727562.0 140000.0 0.2 795903.0 188000.0 0.26 0.3262 0.9908 2069459 Maybridge1_000223 FC(F)(F)c1ccnc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C04 compound treatment 775083.0 188000.0 0.27 830630.0 223000.0 0.31 0.4083 0.9971 2069460 Maybridge1_000224 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=S)NC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C05 compound treatment 793744.0 206000.0 0.29 857822.0 250000.0 0.35 0.4538 0.9963 2069461 Maybridge1_000225 CC(C)(C)OC(=O)NCCNc1ccc(cc1N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C06 compound treatment 793210.0 206000.0 0.29 796153.0 188000.0 0.26 0.3925 0.9986 2069462 Maybridge1_000226 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)Nc2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C07 compound treatment 829922.0 242000.0 0.34 859754.0 252000.0 0.35 0.4921 1.0 2069463 Maybridge1_000227 Cc1nc(ccc1C(=O)Nc2ccccc2F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C08 compound treatment 857555.0 270000.0 0.38 862095.0 254000.0 0.35 0.5222 0.9992 1241428 Maybridge1_000228 Clc1ccc(cc1Cl)C(=O)N2CCN(CC2)c3cccc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C09 compound treatment 860045.0 272000.0 0.39 882743.0 275000.0 0.38 0.5451 1.0 2069464 Maybridge1_000229 FC(F)(F)c1cnc(N2CCCN(CC2)C(=O)Nc3ccc(Cl)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C10 compound treatment 881246.0 294000.0 0.42 872439.0 265000.0 0.37 0.5562 0.9981 2069465 Maybridge1_000230 Cc1ccc(cc1)c2csc3ncnc(NCc4ccco4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C11 compound treatment 858295.0 271000.0 0.39 863513.0 256000.0 0.36 0.5244 0.9993 2069466 Maybridge1_000231 [O-][N+](=O)c1ccc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(F)cc3Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C12 compound treatment 819825.0 232000.0 0.33 827064.0 219000.0 0.31 0.4497 0.9993 2069467 Maybridge1_000232 Fc1ccccc1c2nnn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C13 compound treatment 871621.0 284000.0 0.4 854481.0 247000.0 0.34 0.5288 0.9968 2069468 Maybridge1_000233 Cc1cc(c(C)cc1Cl)S(=O)(=O)NCCNc2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C14 compound treatment 869118.0 282000.0 0.4 851198.0 243000.0 0.34 0.5231 0.9966 2069469 Maybridge1_000234 COc1ccc(NC(=S)NNC(=O)c2ccccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C15 compound treatment 893047.0 305000.0 0.43 935811.0 328000.0 0.46 0.6306 0.9997 2069470 Maybridge1_000235 c1csc(c1)c2ccn(n2)c3nc(ns3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C16 compound treatment 839001.0 251000.0 0.36 871030.0 263000.0 0.37 0.5124 0.9999 2069471 Maybridge1_000236 CCCCCc1ccc(NC(=O)NNc2ccc(F)c(Cl)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C17 compound treatment 882663.0 295000.0 0.42 897487.0 290000.0 0.4 0.5824 0.9998 2069472 Maybridge1_000237 CCCCNC(=O)NCCNc1ccc(cn1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C18 compound treatment 817603.0 230000.0 0.33 809848.0 202000.0 0.28 0.4305 0.9972 2069473 Maybridge1_000238 Cc1cccc(C)c1NC(=S)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C19 compound treatment 853914.0 266000.0 0.38 856300.0 248000.0 0.35 0.5128 0.999 1659799 Maybridge1_000239 CC(C)(C)OC(=O)N1CCCN(CC1)C(=S)Nc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C20 compound treatment 803346.0 216000.0 0.31 820801.0 213000.0 0.3 0.427 0.9999 2069474 Maybridge1_000240 NS(=O)(=O)c1ccc(/N=C/c2ccc3OCOc3c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C21 compound treatment 823173.0 236000.0 0.34 841964.0 234000.0 0.33 0.4678 0.9999 1545894 Maybridge1_000241 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)CC4(CCCC4)C3=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C22 compound treatment 794085.0 207000.0 0.29 817231.0 209000.0 0.29 0.4141 1.0 1922172 Maybridge1_000242 CCOc1ccc(/N=C/c2ccccc2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C23 mock treatment 808878.0 221000.0 0.31 844179.0 236000.0 0.33 0.4556 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 C24 mock treatment 154395.0 -433000.0 -0.62 151356.0 -457000.0 -0.64 -0.8858 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D01 compound treatment 799667.0 212000.0 0.3 862527.0 255000.0 0.36 0.4644 0.9967 2069475 Maybridge1_000243 Clc1cccc(NC(=S)NNC(=O)c2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D02 compound treatment 791662.0 204000.0 0.29 901309.0 293000.0 0.41 0.4946 0.9858 2069476 Maybridge1_000244 COc1cc(/C=N/c2ccc(C)c(Cl)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D03 compound treatment 860412.0 273000.0 0.39 968893.0 361000.0 0.5 0.6304 0.9917 1915764 Maybridge1_000245 O=C(N/N=C/c1cccc2ccccc12)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D04 compound treatment 850620.0 263000.0 0.37 944285.0 336000.0 0.47 0.5963 0.9937 2069477 Maybridge1_000246 CCOC(=O)CSC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D05 compound treatment 895955.0 308000.0 0.44 966401.0 359000.0 0.5 0.6637 0.9979 2069478 Maybridge1_000247 Cc1cc2CSC(SCc2cc1C)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D06 compound treatment 865929.0 278000.0 0.4 910599.0 303000.0 0.42 0.5785 0.9995 2069479 Maybridge1_000248 COc1cc(/C=N/CCCC\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D07 compound treatment 917286.0 330000.0 0.47 997621.0 390000.0 0.54 0.7159 0.9973 2069480 Maybridge1_000249 Clc1c(sc2ccccc12)C(=O)N3/C(=N/c4ccccc4Cl)/SC(=C)C53CCCCC5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D08 compound treatment 921961.0 334000.0 0.48 946574.0 339000.0 0.47 0.6703 1.0 1353182 Maybridge1_000250 Cc1ccc2N(CCCc2c1)C(=S)Nc3c(C)cccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D09 compound treatment 950831.0 363000.0 0.52 1006934.0 399000.0 0.56 0.7588 0.9993 1404608 Maybridge1_000251 COc1ccc(NC(=S)Nc2ccccc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D10 compound treatment 944396.0 357000.0 0.51 961243.0 353000.0 0.49 0.7073 0.9999 1705422 Maybridge1_000252 Clc1cccc(NC(=S)N2CCCc3ccccc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D11 compound treatment 973728.0 386000.0 0.55 980481.0 373000.0 0.52 0.7558 0.9996 2069481 Maybridge1_000253 CC(=O)Nc1ccc(C)c(/N=C/c2ccc(Cl)c(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D12 compound treatment 921715.0 334000.0 0.48 911355.0 303000.0 0.42 0.6353 0.9983 1653449 Maybridge1_000254 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3ccccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D13 compound treatment 972365.0 385000.0 0.55 988137.0 380000.0 0.53 0.762 0.9999 2069482 Maybridge1_000255 OC(=O)CSC(SCC(=O)O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D14 compound treatment 938988.0 351000.0 0.5 935241.0 327000.0 0.46 0.6762 0.999 1541673 Maybridge1_000256 CS(=O)(=O)N(Cc1ccccc1)Cc2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D15 compound treatment 1074092.0 487000.0 0.69 1107095.0 499000.0 0.7 0.9816 1.0 2069483 Maybridge1_000257 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D16 compound treatment 942010.0 354000.0 0.5 985758.0 378000.0 0.53 0.7291 0.9998 1040327 Maybridge1_000258 CC(=O)Nc1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D17 compound treatment 976961.0 389000.0 0.55 994457.0 387000.0 0.54 0.7728 0.9999 2069484 Maybridge1_000259 Cc1ccc(cc1Cl)n2c(C)nc3cc(Cl)ccc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D18 compound treatment 917450.0 330000.0 0.47 938149.0 330000.0 0.46 0.6574 1.0 1578175 Maybridge1_000260 Cc1cc(O)c2cc(F)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D19 compound treatment 925045.0 337000.0 0.48 997251.0 389000.0 0.54 0.7234 0.9981 2069485 Maybridge1_000261 CC(=O)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D20 compound treatment 908499.0 321000.0 0.46 940771.0 333000.0 0.46 0.651 1.0 2069486 Maybridge1_000262 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D21 compound treatment 897054.0 309000.0 0.44 997962.0 390000.0 0.54 0.6959 0.9945 2069487 Maybridge1_000263 COc1ccc(/N=C/c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D22 compound treatment 876501.0 289000.0 0.41 936364.0 328000.0 0.46 0.6145 0.9985 2069488 Maybridge1_000264 COCCCn1c(=O)c2ccccc2[nH]c1=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D23 mock treatment 916683.0 329000.0 0.47 972013.0 364000.0 0.51 0.6901 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 D24 mock treatment 154384.0 -433000.0 -0.62 148087.0 -460000.0 -0.64 -0.889 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E01 compound treatment 810480.0 223000.0 0.32 882325.0 274000.0 0.38 0.4948 0.9956 1245819 Maybridge1_000265 OCCN1CCN(Cc2ccc(F)cc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E02 compound treatment 824578.0 237000.0 0.34 913061.0 305000.0 0.43 0.5393 0.9933 1738877 Maybridge1_000266 CN(C)CCNc1ncnc2scc(c3ccccc3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E03 compound treatment 907653.0 320000.0 0.46 981468.0 374000.0 0.52 0.6903 0.9977 2069489 Maybridge1_000267 CC(=O)Nc1cc(ccc1Sc2ccccc2N)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E04 compound treatment 862626.0 275000.0 0.39 962078.0 354000.0 0.49 0.6259 0.9933 1611827 Maybridge1_000268 CC(C)(C)OC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E05 compound treatment 872226.0 285000.0 0.4 983968.0 376000.0 0.52 0.6572 0.9918 2069490 Maybridge1_000269 FC(F)(F)c1ccnc(n1)N2CCCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E06 compound treatment 863258.0 276000.0 0.39 978951.0 371000.0 0.52 0.6432 0.9906 2069491 Maybridge1_000270 FC(F)(F)c1ccc(NC(=O)N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E07 compound treatment 938448.0 351000.0 0.5 1006187.0 398000.0 0.56 0.7457 0.9986 2069492 Maybridge1_000271 CC(N1CCCCC1)C(=O)Nc2c(C)cccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E08 compound treatment 966342.0 379000.0 0.54 1014219.0 406000.0 0.57 0.7816 0.9997 1434180 Maybridge1_000272 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCN(CC3)c4ncnc5scc(c6ccccc6)c45 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E09 compound treatment 983678.0 396000.0 0.56 1016600.0 409000.0 0.57 0.8014 1.0 2069493 Maybridge1_000273 OC(CNCCNc1nccc(n1)C(F)(F)F)Cn2ccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E10 compound treatment 931120.0 344000.0 0.49 988764.0 381000.0 0.53 0.7211 0.9991 2069494 Maybridge1_000274 Cc1onc(c1C(=O)N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)c6c(Cl)cccc6Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E11 compound treatment 983467.0 396000.0 0.56 1006072.0 398000.0 0.56 0.7908 1.0 1286913 Maybridge1_000275 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E12 compound treatment 967940.0 380000.0 0.54 1008868.0 401000.0 0.56 0.778 0.9999 1722412 Maybridge1_000276 OC(COc1ccc(Cl)c(Cl)c1)CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E13 compound treatment 997798.0 410000.0 0.58 996911.0 389000.0 0.54 0.7962 0.9993 2069495 Maybridge1_000277 FC(F)(F)c1ccnc(NC2CCN(Cc3ccccc3)CC2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E14 compound treatment 957926.0 370000.0 0.53 973111.0 365000.0 0.51 0.7326 0.9999 2069496 Maybridge1_000278 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])c3cnc4ccccc4n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E15 compound treatment 977465.0 390000.0 0.55 1011596.0 404000.0 0.56 0.7902 1.0 2069497 Maybridge1_000279 OC(COc1ccc(cc1)[N+](=O)[O-])CN2CCCN(CC2)c3nc4ccc(Cl)cc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E16 compound treatment 966245.0 379000.0 0.54 986635.0 379000.0 0.53 0.7543 1.0 2069498 Maybridge1_000280 CC(Oc1ccc(Cl)cc1Cl)C(=O)NC2=NCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E17 compound treatment 972994.0 385000.0 0.55 990306.0 382000.0 0.53 0.7647 0.9999 2069499 Maybridge1_000281 FC(F)(F)c1ccnc(NCC=C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E18 compound treatment 945294.0 358000.0 0.51 952248.0 344000.0 0.48 0.6993 0.9996 2069500 Maybridge1_000282 CC(C)c1ccc(/C=C/2\CCC/C(=C\c3ccc(cc3)C(C)C)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E19 compound treatment 955139.0 368000.0 0.52 981757.0 374000.0 0.52 0.7384 1.0 2069501 Maybridge1_000283 FC(F)(F)c1cnc(NCCCNC(=S)Nc2cccnc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E20 compound treatment 920783.0 333000.0 0.47 963709.0 356000.0 0.5 0.686 0.9997 2069502 Maybridge1_000284 Cc1cc(C)nc(NS(=O)(=O)c2ccc(/N=C/c3ccccc3O)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E21 compound treatment 942681.0 355000.0 0.51 1022305.0 414000.0 0.58 0.7658 0.9977 1322088 Maybridge1_000285 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCN(CC3)c4nc5ccc(Cl)cc5s4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E22 compound treatment 916031.0 328000.0 0.47 969252.0 361000.0 0.5 0.6867 0.9993 2069503 Maybridge1_000286 Cc1ccc(/N=C/c2ccccc2O)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E23 mock treatment 965116.0 378000.0 0.54 990153.0 382000.0 0.53 0.7567 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 E24 mock treatment 163814.0 -424000.0 -0.6 166067.0 -442000.0 -0.62 -0.8618 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F01 compound treatment 820131.0 233000.0 0.33 890166.0 282000.0 0.39 0.5123 0.9962 2069504 Maybridge1_000287 Cc1cccc(C)c1NC(=S)NNC(=O)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F02 compound treatment 837612.0 250000.0 0.36 914080.0 306000.0 0.43 0.5534 0.9959 2069505 Maybridge1_000288 Fc1ccc(/N=C/c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F03 compound treatment 902419.0 315000.0 0.45 985717.0 378000.0 0.53 0.6892 0.9967 2069506 Maybridge1_000289 Clc1ccccc1/C=N/NC(=O)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F04 compound treatment 897871.0 310000.0 0.44 990246.0 382000.0 0.53 0.6891 0.9956 2069507 Maybridge1_000290 COC(=O)c1cccc(/N=C/c2cc(Cl)cc(Cl)c2O)c1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F05 compound treatment 929675.0 342000.0 0.49 1002364.0 394000.0 0.55 0.7331 0.9981 2069508 Maybridge1_000291 Cc1cc2CSC(C)(SCc2cc1C)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F06 compound treatment 867018.0 279000.0 0.4 940093.0 332000.0 0.46 0.6087 0.9971 1461154 Maybridge1_000292 CC(N(Cc1ccccc1)C(=S)Nc2ccc(Cl)c(Cl)c2)c3ccccc3O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F07 compound treatment 955659.0 368000.0 0.52 1014582.0 407000.0 0.57 0.7712 0.9992 2069509 Maybridge1_000293 Cc1cccc(Cl)c1/N=C/2\NC3(CCCCC3)C(=C)S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F08 compound treatment 946851.0 359000.0 0.51 987248.0 379000.0 0.53 0.7354 0.9998 1680637 Maybridge1_000294 Cc1cccc(C)c1NC(=S)N2CCCc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F09 compound treatment 917834.0 330000.0 0.47 997353.0 389000.0 0.54 0.7162 0.9974 1024118 Maybridge1_000295 CC(=O)Nc1cc(ccc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F10 compound treatment 943723.0 356000.0 0.51 980840.0 373000.0 0.52 0.726 0.9999 1253012 Maybridge1_000296 Cc1ccc(NC(=S)N2CCCc3cccc(C)c23)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F11 compound treatment 988157.0 401000.0 0.57 1006198.0 398000.0 0.56 0.7957 0.9999 1011159 Maybridge1_000297 CC(=O)Nc1ccc(C)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F12 compound treatment 950831.0 363000.0 0.52 986250.0 378000.0 0.53 0.7385 0.9999 1486966 Maybridge1_000298 Cc1ccc(NC(=S)Nc2ccccc2C(=O)Nc3ccc(F)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F13 compound treatment 969556.0 382000.0 0.54 985334.0 377000.0 0.53 0.7564 0.9999 2069510 Maybridge1_000299 COc1cc(cc(OC)c1OC)C(SCC(=O)O)SCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F14 compound treatment 953074.0 366000.0 0.52 944424.0 337000.0 0.47 0.6995 0.9987 2069511 Maybridge1_000300 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F15 compound treatment 1003731.0 416000.0 0.59 1014838.0 407000.0 0.57 0.8198 0.9998 2069512 Maybridge1_000301 Oc1ccc(Br)cc1/C=N/c2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F16 compound treatment 976723.0 389000.0 0.55 998663.0 391000.0 0.55 0.7767 1.0 1177391 Maybridge1_000302 Oc1ccc(CCc2nnc(S)n2c3ccc(F)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F17 compound treatment 967581.0 380000.0 0.54 1004941.0 397000.0 0.55 0.7737 0.9999 2069513 Maybridge1_000303 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F18 compound treatment 939298.0 352000.0 0.5 921970.0 314000.0 0.44 0.6635 0.9978 1393574 Maybridge1_000304 Cc1cc(O)c2c(Cl)ccc(C)c2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F19 compound treatment 978575.0 391000.0 0.56 967340.0 359000.0 0.5 0.7477 0.9987 1113094 Maybridge1_000305 COC(=O)c1ccccc1NC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F20 compound treatment 956029.0 368000.0 0.52 978465.0 371000.0 0.52 0.736 1.0 2069514 Maybridge1_000306 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F21 compound treatment 978396.0 391000.0 0.56 964354.0 356000.0 0.5 0.7446 0.9985 2069515 Maybridge1_000307 C(/N=C/c1ccc2OCOc2c1)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F22 compound treatment 890455.0 303000.0 0.43 944756.0 337000.0 0.47 0.6368 0.9991 2069516 Maybridge1_000308 COCCCNC(=S)Nc1ccc(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F23 mock treatment 955953.0 368000.0 0.52 994365.0 386000.0 0.54 0.7516 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 F24 mock treatment 138563.0 -449000.0 -0.64 139978.0 -468000.0 -0.65 -0.9129 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G01 compound treatment 785262.0 198000.0 0.28 875889.0 268000.0 0.37 0.4631 0.9901 2069517 Maybridge1_000309 On1nnc2ccc(cc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G02 compound treatment 817555.0 230000.0 0.33 883559.0 276000.0 0.38 0.5032 0.9968 2069518 Maybridge1_000310 CCOC(=O)c1cc(C(=S)N)c(C)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G03 compound treatment 877784.0 290000.0 0.41 939883.0 332000.0 0.46 0.6193 0.9984 1521295 Maybridge1_000311 CCOC(=O)C1CCN(CC1)c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G04 compound treatment 854505.0 267000.0 0.38 950373.0 343000.0 0.48 0.6062 0.9935 2069519 Maybridge1_000312 CC(C)(C)OC(=O)NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G05 compound treatment 856968.0 269000.0 0.38 971954.0 364000.0 0.51 0.63 0.9903 2069520 Maybridge1_000313 Fc1cccc(Cl)c1CN2CCN(CC2)c3nccc(n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G06 compound treatment 860466.0 273000.0 0.39 947714.0 340000.0 0.47 0.6096 0.9951 2069521 Maybridge1_000314 COc1ccccc1NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G07 compound treatment 895457.0 308000.0 0.44 1030520.0 423000.0 0.59 0.7264 0.9893 1674114 Maybridge1_000315 CCc1ccccc1n2c(S)nc3ccccc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G08 compound treatment 924646.0 337000.0 0.48 885790.0 278000.0 0.39 0.613 0.9944 2069522 Maybridge1_000316 CCCCCc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G09 compound treatment 966071.0 379000.0 0.54 1010060.0 402000.0 0.56 0.7773 0.9998 2069523 Maybridge1_000317 OC1CCCCC1NCCNc2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G10 compound treatment 876112.0 289000.0 0.41 988562.0 381000.0 0.53 0.6656 0.9919 2069524 Maybridge1_000318 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G11 compound treatment 930042.0 342000.0 0.49 969573.0 362000.0 0.5 0.7011 0.9998 2069525 Maybridge1_000319 CC(C)(C)c1ccc(NC(=O)N2CCCN(CC2)c3ccc(cn3)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G12 compound treatment 940533.0 353000.0 0.5 943936.0 336000.0 0.47 0.6864 0.9994 2069526 Maybridge1_000320 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)NCCCN2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G13 compound treatment 978743.0 391000.0 0.56 988107.0 380000.0 0.53 0.7683 0.9997 1664341 Maybridge1_000321 S=C(NCC1CC1)Nc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G14 compound treatment 930320.0 343000.0 0.49 986090.0 378000.0 0.53 0.7177 0.9992 1019841 Maybridge1_000322 Cc1ccccc1C(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G15 compound treatment 965627.0 378000.0 0.54 1050556.0 443000.0 0.62 0.8167 0.9976 2069527 Maybridge1_000323 FC(F)(F)c1ccnc(n1)n2ccc(n2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G16 compound treatment 928665.0 341000.0 0.49 964942.0 357000.0 0.5 0.6951 0.9999 1780339 Maybridge1_000324 [O-][N+](=O)c1ccc(o1)C(=O)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G17 compound treatment 954431.0 367000.0 0.52 1025106.0 417000.0 0.58 0.7804 0.9985 2069528 Maybridge1_000325 FC(F)(F)c1ccnc(NCCN2C(=O)CC3(CCCC3)C2=O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G18 compound treatment 938157.0 351000.0 0.5 990824.0 383000.0 0.53 0.7302 0.9994 2069529 Maybridge1_000326 CC/1CC(C)(C)C\C1=N/Nc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G19 compound treatment 967184.0 380000.0 0.54 1006691.0 399000.0 0.56 0.7751 0.9999 2069530 Maybridge1_000327 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2ccc(nc2C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G20 compound treatment 898314.0 311000.0 0.44 963249.0 355000.0 0.5 0.663 0.9984 2069531 Maybridge1_000328 C/C(=N\N=C(/C)\c1ccc(C)cc1)/c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G21 compound treatment 943898.0 356000.0 0.51 988208.0 380000.0 0.53 0.7334 0.9997 2069532 Maybridge1_000329 CC(C)(C)OC(=O)NCCNc1ccc(cc1N2C(=O)CC3(CCCC3)C2=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G22 compound treatment 887180.0 300000.0 0.43 944525.0 337000.0 0.47 0.6333 0.9988 2069533 Maybridge1_000330 CC(=O)Nc1ccc(Br)cc1C(=O)C(=O)Nc2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G23 mock treatment 930060.0 342000.0 0.49 996684.0 389000.0 0.54 0.7279 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 G24 mock treatment 166171.0 -421000.0 -0.6 168225.0 -440000.0 -0.61 -0.8573 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H01 compound treatment 841223.0 254000.0 0.36 859516.0 252000.0 0.35 0.5032 0.9999 1944160 Maybridge1_000331 O=C(NNC(=S)Nc1ccccc1)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H02 compound treatment 821366.0 234000.0 0.33 903190.0 295000.0 0.41 0.5264 0.9944 2069534 Maybridge1_000332 Fc1ccc(cc1)N2C(SCC2=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H03 compound treatment 858866.0 271000.0 0.39 967933.0 360000.0 0.5 0.6279 0.9915 2069535 Maybridge1_000333 CC(=O)N1N=C(OC1c2ccccc2Cl)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H04 compound treatment 840440.0 253000.0 0.36 917399.0 310000.0 0.43 0.5595 0.9959 2069536 Maybridge1_000334 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)SCC(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H05 compound treatment 864201.0 277000.0 0.39 942296.0 334000.0 0.47 0.608 0.9964 2069537 Maybridge1_000335 Cc1cc2CSC(C)(SCc2cc1C)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H06 compound treatment 900476.0 313000.0 0.44 926900.0 319000.0 0.44 0.6293 1.0 2069538 Maybridge1_000336 NNS(=O)(=O)c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H07 compound treatment 908080.0 321000.0 0.46 978752.0 371000.0 0.52 0.6881 0.998 1917064 Maybridge1_000337 S=c1nc2[nH]c3ccccc3c2n[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H08 compound treatment 946572.0 359000.0 0.51 959095.0 351000.0 0.49 0.7074 0.9998 2069539 Maybridge1_000338 FC(F)(F)c1cccc(NC(=S)N2CCc3ccccc3C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H09 compound treatment 948515.0 361000.0 0.51 991965.0 384000.0 0.54 0.7418 0.9998 1048074 Maybridge1_000339 CN(C)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H10 compound treatment 936982.0 349000.0 0.5 955187.0 347000.0 0.48 0.6939 0.9999 1205163 Maybridge1_000340 Cc1ccc(NC(=S)N2CCCc3ccccc23)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H11 compound treatment 924744.0 337000.0 0.48 953903.0 346000.0 0.48 0.6803 1.0 2069540 Maybridge1_000341 COc1nc(Nc2cccc(c2)C(F)(F)F)nc(OC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H12 compound treatment 891521.0 304000.0 0.43 942893.0 335000.0 0.47 0.6361 0.9992 1127694 Maybridge1_000342 Fc1ccc(NC(=O)c2ccccc2NC(=S)Nc3ccc(Cl)c(Cl)c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H13 compound treatment 913371.0 326000.0 0.46 938458.0 331000.0 0.46 0.6536 1.0 2069541 Maybridge1_000343 OC(=O)CSC(SCC(=O)O)c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H14 compound treatment 952522.0 365000.0 0.52 939517.0 332000.0 0.46 0.6941 0.9984 2069542 Maybridge1_000344 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(C)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H15 compound treatment 961195.0 374000.0 0.53 994836.0 387000.0 0.54 0.7573 1.0 1367412 Maybridge1_000345 CCOC(=O)c1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(F)cc3)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H16 compound treatment 913242.0 326000.0 0.46 979050.0 371000.0 0.52 0.6936 0.9985 1578868 Maybridge1_000346 Cc1c(Cl)cccc1n2c(S)nnc2CCc3ccc(O)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H17 compound treatment 961463.0 374000.0 0.53 1025901.0 418000.0 0.58 0.7882 0.9989 1141423 Maybridge1_000347 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H18 compound treatment 904652.0 317000.0 0.45 958790.0 351000.0 0.49 0.6649 0.9992 1562593 Maybridge1_000348 Cc1cc(O)c2cc(Cl)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H19 compound treatment 932368.0 345000.0 0.49 987167.0 379000.0 0.53 0.7208 0.9993 1160657 Maybridge1_000349 COC(=O)c1ccccc1NC(=O)c2cc(OC)c(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H20 compound treatment 951563.0 364000.0 0.52 986160.0 378000.0 0.53 0.7391 1.0 2069543 Maybridge1_000350 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cc(Cl)cc(Cl)c2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H21 compound treatment 941763.0 354000.0 0.5 965396.0 358000.0 0.5 0.7088 1.0 1285265 Maybridge1_000351 CCOC(=O)C1CCN(CC1)c2nc(OC)nc(OC)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H22 compound treatment 873409.0 286000.0 0.41 848379.0 241000.0 0.34 0.5246 0.9954 2069544 Maybridge1_000352 CN(C)c1ccc(/C=N/c2ccc(cc2)N3N=C(C)CC3=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H23 mock treatment 928085.0 341000.0 0.48 964201.0 356000.0 0.5 0.6938 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 H24 mock treatment 151901.0 -436000.0 -0.62 134917.0 -473000.0 -0.66 -0.9045 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I01 compound treatment 818276.0 231000.0 0.33 895556.0 288000.0 0.4 0.5157 0.995 1454622 Maybridge1_000353 OCCN1CCN(CC1)c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I02 compound treatment 857501.0 270000.0 0.38 946358.0 338000.0 0.47 0.6053 0.9947 2069545 Maybridge1_000354 NC1CCN(CC1)c2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I03 compound treatment 856398.0 269000.0 0.38 976594.0 369000.0 0.51 0.634 0.9893 1575257 Maybridge1_000355 Clc1ccc2nc(sc2c1)N3CCCNCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I04 compound treatment 849961.0 262000.0 0.37 997302.0 389000.0 0.54 0.6479 0.9832 1654743 Maybridge1_000356 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I05 compound treatment 895664.0 308000.0 0.44 1001159.0 393000.0 0.55 0.6977 0.9938 1266004 Maybridge1_000357 CCOC(=O)c1c(N)scc1C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I06 compound treatment 873884.0 286000.0 0.41 995185.0 387000.0 0.54 0.6699 0.9903 2069546 Maybridge1_000358 FC(F)(F)c1ccc(NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I07 compound treatment 898623.0 311000.0 0.44 989494.0 382000.0 0.53 0.6892 0.9958 2069547 Maybridge1_000359 Cc1nc(ccc1C#N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I08 compound treatment 933713.0 346000.0 0.49 966245.0 358000.0 0.5 0.7015 1.0 2069548 Maybridge1_000360 Cc1nc(nc(N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1Cl)c4cccnc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I09 compound treatment 957470.0 370000.0 0.53 1020222.0 412000.0 0.58 0.7786 0.999 2069549 Maybridge1_000361 CC(C)(C)OC(=O)N/N=C\c1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I10 compound treatment 931514.0 344000.0 0.49 945154.0 337000.0 0.47 0.6785 0.9998 2069550 Maybridge1_000362 Cc1c(sc2ncnc(O)c12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I11 compound treatment 925320.0 338000.0 0.48 995092.0 387000.0 0.54 0.7215 0.9983 1256094 Maybridge1_000363 OC(CNC1CCN(Cc2ccccc2)CC1)COc3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I12 compound treatment 941175.0 354000.0 0.5 985646.0 378000.0 0.53 0.7281 0.9997 2069551 Maybridge1_000364 FC(F)(F)c1ccnc(n1)N2CCN(CCCNC(=O)c3cccs3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I13 compound treatment 954223.0 367000.0 0.52 962748.0 355000.0 0.49 0.7187 0.9997 1454379 Maybridge1_000365 S=C(NCc1ccco1)Nc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I14 compound treatment 930347.0 343000.0 0.49 993045.0 385000.0 0.54 0.7246 0.9988 1651773 Maybridge1_000366 COC(=O)c1ccc(CSc2ccccc2NC(=S)Nc3cccc(SC)c3)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I15 compound treatment 976416.0 389000.0 0.55 991151.0 383000.0 0.53 0.769 0.9999 2069552 Maybridge1_000367 [O-][N+](=O)c1cc(ccc1n2ccc(n2)c3cccs3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I16 compound treatment 917223.0 330000.0 0.47 970538.0 363000.0 0.51 0.6892 0.9993 2069553 Maybridge1_000368 CCOC(=O)c1ccc(NC(=O)c2ccc(o2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I17 compound treatment 984520.0 397000.0 0.56 1046900.0 439000.0 0.61 0.8321 0.9992 2069554 Maybridge1_000369 FC(F)(F)c1cccnc1NCCN2C(=O)CC3(CCCC3)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I18 compound treatment 930499.0 343000.0 0.49 969028.0 361000.0 0.5 0.701 0.9999 1352465 Maybridge1_000370 CC(C)c1ccc(NC2(CCCCC2)C(=O)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I19 compound treatment 930456.0 343000.0 0.49 1006208.0 398000.0 0.56 0.7376 0.9979 2069555 Maybridge1_000371 COc1ccc(OCC(O)CNCCNc2ncccc2C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I20 compound treatment 943428.0 356000.0 0.51 948330.0 340000.0 0.47 0.6936 0.9995 2069556 Maybridge1_000372 C/C(=N\N=C(/C)\c1ccc(C)cc1C)/c2ccc(C)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I21 compound treatment 980014.0 392000.0 0.56 1036171.0 428000.0 0.6 0.817 0.9994 1262020 Maybridge1_000373 OC(CN1CCC(CC1)NC2CCCCC2O)Cn3ccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I22 compound treatment 926322.0 339000.0 0.48 977415.0 370000.0 0.52 0.7051 0.9994 2069557 Maybridge1_000374 COc1ccc(cc1)/C(=N/N=C/c2cc(OC)c(OC)c(OC)c2)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I23 mock treatment 959668.0 372000.0 0.53 1013040.0 405000.0 0.57 0.7738 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 I24 mock treatment 137421.0 -450000.0 -0.64 170635.0 -437000.0 -0.61 -0.8838 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J01 compound treatment 846392.0 259000.0 0.37 865014.0 257000.0 0.36 0.5139 0.9999 2069558 Maybridge1_000375 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)c2sc3ccccc3c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J02 compound treatment 849617.0 262000.0 0.37 908688.0 301000.0 0.42 0.5602 0.9983 2069559 Maybridge1_000376 COc1cc(NS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J03 compound treatment 885861.0 298000.0 0.42 960192.0 352000.0 0.49 0.6474 0.9973 2069560 Maybridge1_000377 COc1ccc(/C=N/NC(=O)c2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J04 compound treatment 870339.0 283000.0 0.4 950775.0 343000.0 0.48 0.6225 0.9963 2069561 Maybridge1_000378 COc1ccc(cc1)c2nnc(S)n2c3cccc(OC)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J05 compound treatment 869602.0 282000.0 0.4 968874.0 361000.0 0.5 0.6396 0.9937 2069562 Maybridge1_000379 COc1cc(ccc1O)C2(C)SCc3cc(C)c(C)cc3CS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J06 compound treatment 885212.0 298000.0 0.42 908807.0 301000.0 0.42 0.5961 1.0 2069563 Maybridge1_000380 CC(SCC(=O)O)(SCC(=O)O)c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J07 compound treatment 934534.0 347000.0 0.49 948366.0 340000.0 0.47 0.6847 0.9998 1140994 Maybridge1_000381 Cc1onc(c1C(=O)N2CCc3ccccc3C2)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J08 compound treatment 927720.0 340000.0 0.48 949149.0 341000.0 0.48 0.6786 1.0 2069564 Maybridge1_000382 Cc1cccc2CCCN(C(=S)Nc3cccc(c3)C(F)(F)F)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J09 compound treatment 943409.0 356000.0 0.51 961971.0 354000.0 0.49 0.707 0.9999 1048961 Maybridge1_000383 COc1cc(cc(OC)c1OC)C2Nc3cccc4cccc(N2)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J10 compound treatment 944064.0 357000.0 0.51 950176.0 342000.0 0.48 0.6961 0.9995 2069565 Maybridge1_000384 Oc1ccc(CCC(=O)N/N=C/c2ccc(Cl)c(Cl)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J11 compound treatment 961243.0 374000.0 0.53 992168.0 384000.0 0.54 0.7548 1.0 2069566 Maybridge1_000385 Cc1ccc(Nc2nc3ccccc3s2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J12 compound treatment 925070.0 338000.0 0.48 899653.0 292000.0 0.41 0.6271 0.9966 2069567 Maybridge1_000386 Oc1ccc(CCC(=O)NNC(=S)Nc2cccc(c2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J13 compound treatment 981787.0 394000.0 0.56 943685.0 336000.0 0.47 0.7276 0.996 1383075 Maybridge1_000387 CC1CC(=O)Nc2ccccc2N1C(=O)c3c(C)onc3c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J14 compound treatment 930805.0 343000.0 0.49 976970.0 369000.0 0.51 0.7092 0.9996 2069568 Maybridge1_000388 CC(C)N(Cc1ccc(cc1)N(C)C)C(=S)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J15 compound treatment 926962.0 339000.0 0.48 993691.0 386000.0 0.54 0.7218 0.9985 1030886 Maybridge1_000389 CC(=O)Nc1cc(Cl)ccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J16 compound treatment 933802.0 346000.0 0.49 939727.0 332000.0 0.46 0.6754 0.9995 1516286 Maybridge1_000390 Cc1ccc(c(C)c1)n2c(S)nnc2CCc3ccc(O)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J17 compound treatment 982687.0 395000.0 0.56 988037.0 380000.0 0.53 0.7722 0.9996 2069569 Maybridge1_000391 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccccc2C(=O)Nc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J18 compound treatment 932108.0 345000.0 0.49 960803.0 353000.0 0.49 0.6945 1.0 2069570 Maybridge1_000392 Cc1ccc(NS(=O)(=O)C)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J19 compound treatment 947854.0 360000.0 0.51 962767.0 355000.0 0.49 0.7123 0.9999 1040131 Maybridge1_000393 CC1CC(=O)Nc2cc(C)c(C)cc2N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J20 compound treatment 909534.0 322000.0 0.46 951562.0 344000.0 0.48 0.6627 0.9997 2069571 Maybridge1_000394 Cc1ccc(NS(=O)(=O)C)cc1/N=C/c2cc(Br)ccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J21 compound treatment 945961.0 358000.0 0.51 935838.0 328000.0 0.46 0.6838 0.9985 1635307 Maybridge1_000395 Clc1c(sc2ccccc12)C(=O)N3CCCc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J22 compound treatment 890774.0 303000.0 0.43 880917.0 273000.0 0.38 0.5742 0.9981 2069572 Maybridge1_000396 CC(C)CCCC(C)C1CCC2C3CC=C4C[C@H](CC[C@]4(C)C3CC[C@]12C)OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J23 mock treatment 963219.0 376000.0 0.53 974624.0 367000.0 0.51 0.7394 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 J24 mock treatment 151681.0 -436000.0 -0.62 139758.0 -468000.0 -0.65 -0.9 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K01 compound treatment 841671.0 254000.0 0.36 889739.0 282000.0 0.39 0.5335 0.9991 2069573 Maybridge1_000397 OCCN1CCN(CC1)c2ncccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K02 compound treatment 826385.0 239000.0 0.34 917799.0 310000.0 0.43 0.5458 0.9929 1587186 Maybridge1_000398 OC(CNCc1ccc2OCOc2c1)COc3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K03 compound treatment 874303.0 287000.0 0.41 968591.0 361000.0 0.5 0.6441 0.9946 1185686 Maybridge1_000399 OCCN1CCN(Cc2ccccc2F)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K04 compound treatment 841488.0 254000.0 0.36 945896.0 338000.0 0.47 0.5887 0.9913 1632887 Maybridge1_000400 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K05 compound treatment 855283.0 268000.0 0.38 970148.0 362000.0 0.51 0.6265 0.9903 2069574 Maybridge1_000401 OC1CCN(CC1)c2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K06 compound treatment 864233.0 277000.0 0.39 885301.0 277000.0 0.39 0.5518 1.0 2069575 Maybridge1_000402 CCc1cccc(C)c1NC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K07 compound treatment 912422.0 325000.0 0.46 931111.0 323000.0 0.45 0.6454 0.9999 2069576 Maybridge1_000403 Cc1nc(ccc1C(=O)NN)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K08 compound treatment 901560.0 314000.0 0.45 951168.0 343000.0 0.48 0.6543 0.9994 1289970 Maybridge1_000404 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K09 compound treatment 903805.0 316000.0 0.45 993045.0 385000.0 0.54 0.6979 0.9961 2069577 Maybridge1_000405 CCOC(=O)c1cc(c2nc(cs2)C(=O)NN)c(C)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K10 compound treatment 927488.0 340000.0 0.48 980999.0 373000.0 0.52 0.7098 0.9993 2069578 Maybridge1_000406 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCNc2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K11 compound treatment 871526.0 284000.0 0.4 936010.0 328000.0 0.46 0.6092 0.9981 2069579 Maybridge1_000407 FC(F)(F)c1ccnc(NCCNC(=O)c2cccs2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K12 compound treatment 904456.0 317000.0 0.45 919275.0 311000.0 0.43 0.6258 0.9998 1651621 Maybridge1_000408 CCCc1cnc(nc1)N2CCCN(CC2)C(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K13 compound treatment 946563.0 359000.0 0.51 984159.0 376000.0 0.52 0.7321 0.9999 2069580 Maybridge1_000409 FC(F)(F)c1ccnc(NCCNC(=S)Nc2cccnc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K14 compound treatment 931675.0 344000.0 0.49 967242.0 359000.0 0.5 0.7004 0.9999 2069581 Maybridge1_000410 CC(=O)c1cc(Cl)cc(Cl)c1OC(=O)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K15 compound treatment 942267.0 355000.0 0.5 991151.0 383000.0 0.53 0.7347 0.9996 1570851 Maybridge1_000411 CCCc1cnc(nc1)N2CCCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K16 compound treatment 909705.0 322000.0 0.46 983668.0 376000.0 0.52 0.6945 0.9977 2069582 Maybridge1_000412 FC(F)(F)c1cccc(NC(=S)NCc2ccco2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K17 compound treatment 894379.0 307000.0 0.44 1019520.0 412000.0 0.57 0.7145 0.9908 2069583 Maybridge1_000413 Cc1nc(ccc1NC(=O)NCCNc2nccc(n2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K18 compound treatment 917878.0 330000.0 0.47 954629.0 347000.0 0.48 0.6741 0.9999 2069584 Maybridge1_000414 NC(=O)C1(CCCCC1)NC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K19 compound treatment 937555.0 350000.0 0.5 1012254.0 404000.0 0.56 0.7507 0.9981 1388914 Maybridge1_000415 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K20 compound treatment 896479.0 309000.0 0.44 963142.0 355000.0 0.5 0.661 0.9982 1913698 Maybridge1_000416 COc1ccc(cc1)/C(=N/N=C(\C)/c2ccc(OC)cc2)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K21 compound treatment 939681.0 352000.0 0.5 1009659.0 402000.0 0.56 0.7503 0.9984 1018970 Maybridge1_000417 OC(CNCc1ccccc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K22 compound treatment 876518.0 289000.0 0.41 933766.0 326000.0 0.45 0.612 0.9987 2069585 Maybridge1_000418 COc1cc(/C=N/Nc2ccccc2)ccc1OC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K23 mock treatment 924097.0 337000.0 0.48 986623.0 379000.0 0.53 0.7119 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 K24 mock treatment 166276.0 -421000.0 -0.6 173432.0 -434000.0 -0.61 -0.8521 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L01 compound treatment 830300.0 243000.0 0.35 826520.0 219000.0 0.3 0.4597 0.9981 1429726 Maybridge1_000419 CC(=O)N1N=C(OC1(C)C)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L02 compound treatment 824424.0 237000.0 0.34 870551.0 263000.0 0.37 0.4972 0.9991 2069586 Maybridge1_000420 Cc1cc(C)c(NS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L03 compound treatment 868008.0 280000.0 0.4 897237.0 289000.0 0.4 0.5674 1.0 2069587 Maybridge1_000421 COc1cc(/C=N/CC\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L04 compound treatment 865890.0 278000.0 0.4 900619.0 293000.0 0.41 0.5686 0.9999 2069588 Maybridge1_000422 COc1ccc(cc1)c2nnc(S)n2c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L05 compound treatment 903349.0 316000.0 0.45 935966.0 328000.0 0.46 0.6411 1.0 2069589 Maybridge1_000423 CC1CCCCC21SCc3cc(C)c(C)cc3CS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L06 compound treatment 867065.0 280000.0 0.4 883681.0 276000.0 0.38 0.5531 0.9999 2069590 Maybridge1_000424 CCCC(C)(SCC(=O)O)SCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L07 compound treatment 939764.0 352000.0 0.5 928745.0 321000.0 0.45 0.6706 0.9984 1367544 Maybridge1_000425 COc1ccc(NC(=O)C)c(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L08 compound treatment 915293.0 328000.0 0.47 911131.0 303000.0 0.42 0.6286 0.9988 2069591 Maybridge1_000426 FC(F)(F)c1cccc(NC(=S)N2CCCc3ccccc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L09 compound treatment 920458.0 333000.0 0.47 949057.0 341000.0 0.48 0.6712 1.0 1178859 Maybridge1_000427 C1Oc2ccc(cc2O1)C3Nc4cccc5cccc(N3)c45 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L10 compound treatment 905287.0 318000.0 0.45 944924.0 337000.0 0.47 0.6519 0.9998 2069592 Maybridge1_000428 COc1cc(/C=N/NC(=O)CCc2ccc(O)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L11 compound treatment 944591.0 357000.0 0.51 955914.0 348000.0 0.49 0.7023 0.9997 1177022 Maybridge1_000429 COc1cccc(Nc2nc3ccccc3s2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L12 compound treatment 922887.0 335000.0 0.48 936973.0 329000.0 0.46 0.6618 0.9998 2069593 Maybridge1_000430 Cc1ccccc1NC(=S)NNC(=O)CCc2ccc(O)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L13 compound treatment 928638.0 341000.0 0.49 888625.0 281000.0 0.39 0.6199 0.9944 1242977 Maybridge1_000431 CC1CC(=O)Nc2ccccc2N1C(=O)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L14 compound treatment 917467.0 330000.0 0.47 915823.0 308000.0 0.43 0.6354 0.999 2069594 Maybridge1_000432 Clc1ccc(CNC(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L15 compound treatment 956190.0 369000.0 0.52 1005213.0 397000.0 0.55 0.7625 0.9996 2069595 Maybridge1_000433 C(/N=C/c1ccc2OCOc2c1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L16 compound treatment 870316.0 283000.0 0.4 928540.0 321000.0 0.45 0.6006 0.9986 1485674 Maybridge1_000434 Oc1ccc(CCc2nnc(S)n2c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L17 compound treatment 950720.0 363000.0 0.52 908995.0 301000.0 0.42 0.6621 0.9947 2069596 Maybridge1_000435 Cc1ccc(SCC(=O)c2cccc(c2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L18 compound treatment 936637.0 349000.0 0.5 969758.0 362000.0 0.5 0.7079 1.0 2069597 Maybridge1_000436 Cc1ccc(/N=C/c2cc(Cl)cc(Cl)c2O)cc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L19 compound treatment 952840.0 365000.0 0.52 966052.0 358000.0 0.5 0.7206 0.9998 2069598 Maybridge1_000437 Cc1ccc2nc(C)oc(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L20 compound treatment 900173.0 313000.0 0.44 913554.0 306000.0 0.43 0.6158 0.9998 2069599 Maybridge1_000438 CN(C)c1ccc(/C=N/c2cc(NS(=O)(=O)C)ccc2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L21 compound treatment 979220.0 392000.0 0.56 993117.0 385000.0 0.54 0.7738 0.9998 1294233 Maybridge1_000439 Cc1ccc2N(CCCc2c1)C(=O)c3sc4ccccc4c3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L22 compound treatment 908003.0 320000.0 0.46 878167.0 270000.0 0.38 0.5888 0.9956 2069600 Maybridge1_000440 COc1cc(/C=N/c2ccc(cc2)N3N=C(C)CC3=O)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L23 mock treatment 957545.0 370000.0 0.53 972943.0 365000.0 0.51 0.7321 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 L24 mock treatment 166224.0 -421000.0 -0.6 167376.0 -440000.0 -0.61 -0.8581 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M01 compound treatment 816145.0 229000.0 0.33 890576.0 283000.0 0.39 0.5087 0.9954 1610519 Maybridge1_000441 Cc1nc(nc(N2CCN(CCO)CC2)c1Cl)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M02 compound treatment 822171.0 235000.0 0.33 921338.0 313000.0 0.44 0.5451 0.9911 2069601 Maybridge1_000442 COc1ccccc1NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M03 compound treatment 868961.0 281000.0 0.4 976171.0 368000.0 0.51 0.6462 0.9924 1254354 Maybridge1_000443 C1CNCCN(C1)c2nc(ns2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M04 compound treatment 871195.0 284000.0 0.4 956967.0 349000.0 0.49 0.6295 0.9956 1391909 Maybridge1_000444 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M05 compound treatment 895448.0 308000.0 0.44 996324.0 388000.0 0.54 0.6927 0.9944 2069602 Maybridge1_000445 [O-][N+](=O)c1ccc(nc1)N2CCCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M06 compound treatment 863521.0 276000.0 0.39 938549.0 331000.0 0.46 0.6036 0.9968 1581293 Maybridge1_000446 C1CN(CCN1)c2ncnc3scc(c4ccccc4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M07 compound treatment 908661.0 321000.0 0.46 983908.0 376000.0 0.52 0.6937 0.9976 1364451 Maybridge1_000447 Clc1ccc(CN2CCCN(CC2)C(=O)Nc3cccc(Cl)c3Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M08 compound treatment 906665.0 319000.0 0.45 940221.0 332000.0 0.46 0.6486 0.9999 1658768 Maybridge1_000448 Cc1nc(nc(N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)c1Cl)c6ccccn6 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M09 compound treatment 913078.0 326000.0 0.46 977931.0 370000.0 0.52 0.6923 0.9985 2069603 Maybridge1_000449 OC(CNCCNc1ncccc1C(F)(F)F)COc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M10 compound treatment 897604.0 310000.0 0.44 936537.0 329000.0 0.46 0.6359 0.9998 2069604 Maybridge1_000450 CC(=O)c1ccc(OCc2c(F)cccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M11 compound treatment 938923.0 351000.0 0.5 1002729.0 395000.0 0.55 0.7427 0.9988 2069605 Maybridge1_000451 FC(F)(F)c1ccnc(NCCNC(=O)c2ccco2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M12 compound treatment 1063434.0 476000.0 0.68 1290287.0 682000.0 0.95 1.1515 0.986 1301777 Maybridge1_000452 Nc1oc(cc1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M13 compound treatment 962364.0 375000.0 0.53 1000692.0 393000.0 0.55 0.7643 0.9999 1198042 Maybridge1_000453 S=C(NC1CCN(Cc2ccccc2)CC1)Nc3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M14 compound treatment 919119.0 332000.0 0.47 974869.0 367000.0 0.51 0.6953 0.9992 2069606 Maybridge1_000454 CCCCCc1ccc(cc1)C(=O)O/N=C/c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M15 compound treatment 936682.0 349000.0 0.5 1006901.0 399000.0 0.56 0.7446 0.9984 1500883 Maybridge1_000455 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M16 compound treatment 902926.0 315000.0 0.45 964373.0 357000.0 0.5 0.6687 0.9987 1229893 Maybridge1_000456 COc1cccc(NC(=S)NCc2ccco2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M17 compound treatment 951722.0 364000.0 0.52 996777.0 389000.0 0.54 0.7497 0.9997 2069607 Maybridge1_000457 FC(F)(F)c1cnc(NCCCN2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M18 compound treatment 914540.0 327000.0 0.46 973052.0 365000.0 0.51 0.6889 0.999 1497535 Maybridge1_000458 OC1(CC(=O)c2ccc3ccccc3c2)C(=O)Nc4ccc(Br)cc41 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M19 compound treatment 952191.0 365000.0 0.52 1005623.0 398000.0 0.55 0.7589 0.9994 2069608 Maybridge1_000459 Cc1nc(ccc1NC(=O)N2CCCN(Cc3c(F)cccc3Cl)CC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M20 compound treatment 906750.0 319000.0 0.45 965174.0 357000.0 0.5 0.6733 0.9989 1920853 Maybridge1_000460 C/C(=N\N=C(/C)\c1ccc(F)cc1)/c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M21 compound treatment 897104.0 310000.0 0.44 975026.0 367000.0 0.51 0.6734 0.9972 1742985 Maybridge1_000461 COc1ccccc1C2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M22 compound treatment 893063.0 305000.0 0.43 963988.0 356000.0 0.5 0.6584 0.9978 2069609 Maybridge1_000462 COC(=O)c1sc2ccccc2c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M23 mock treatment 934389.0 347000.0 0.49 959524.0 352000.0 0.49 0.6956 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 M24 mock treatment 681756.0 94200.0 0.13 750160.0 142000.0 0.2 0.235 0.9817 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N01 compound treatment 863675.0 276000.0 0.39 833123.0 225000.0 0.31 0.4998 0.9939 1061248 Maybridge1_000463 CC(=NNC(=O)c1cccnc1)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N02 compound treatment 853054.0 265000.0 0.38 880185.0 272000.0 0.38 0.5355 1.0 2069610 Maybridge1_000464 Fc1ccc(NC(=O)CSC(=O)c2sc3ccccc3c2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N03 compound treatment 894072.0 307000.0 0.44 933558.0 326000.0 0.45 0.6294 0.9998 1918851 Maybridge1_000465 C(C/N=C/c1ccc2OCOc2c1)/N=C/c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N04 compound treatment 869720.0 282000.0 0.4 912104.0 304000.0 0.42 0.5838 0.9996 2069611 Maybridge1_000466 COc1ccc(cc1)c2nnc(S)n2c3ccc(Cl)cc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N05 compound treatment 925736.0 338000.0 0.48 911768.0 304000.0 0.42 0.6398 0.998 1155620 Maybridge1_000467 Cc1ccc2nc(oc(=O)c2c1)c3sc4ccccc4c3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N06 compound treatment 854663.0 267000.0 0.38 850680.0 243000.0 0.34 0.508 0.9984 1731343 Maybridge1_000468 COc1ccc(CC2N(CCc3cc(OC)c(OC)cc23)C(=S)Nc4ccc(Cl)cc4C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N07 compound treatment 954818.0 367000.0 0.52 919783.0 312000.0 0.44 0.6769 0.9959 1680835 Maybridge1_000469 COc1cccc(NC(=S)Nc2ccc(OC)c(OC)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N08 compound treatment 911811.0 324000.0 0.46 920503.0 313000.0 0.44 0.6344 0.9996 1443259 Maybridge1_000470 Cc1cccc2CCCN(C(=S)Nc3ccccc3Cl)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N09 compound treatment 969127.0 382000.0 0.54 981697.0 374000.0 0.52 0.7524 0.9998 1532986 Maybridge1_000471 CCOC(=O)C1CCN(CC1)C(=S)Nc2cccc(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N10 compound treatment 908439.0 321000.0 0.46 925682.0 318000.0 0.44 0.6361 0.9999 2069612 Maybridge1_000472 Oc1ccc(CCC(=O)N/N=C/C=C/c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N11 compound treatment 964498.0 377000.0 0.54 957497.0 350000.0 0.49 0.7238 0.9989 1025368 Maybridge1_000473 CC1CC(=O)Nc2ccccc2N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N12 compound treatment 908670.0 321000.0 0.46 910314.0 302000.0 0.42 0.6212 0.9992 2069613 Maybridge1_000474 Fc1ccc(cc1)N(Cc2ccc3OCOc3c2)C(=S)Nc4ccc(Cl)c(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N13 compound treatment 969709.0 382000.0 0.54 938595.0 331000.0 0.46 0.7104 0.9967 1356457 Maybridge1_000475 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N14 compound treatment 991923.0 404000.0 0.58 976436.0 369000.0 0.51 0.7701 0.9984 2069614 Maybridge1_000476 Oc1c(Cl)cc(Cl)cc1/C=N/Cc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N15 compound treatment 1034872.0 447000.0 0.64 1035349.0 427000.0 0.6 0.8714 0.9995 2069615 Maybridge1_000477 Clc1cc(Cl)cc(/C=N/Cc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N16 compound treatment 932593.0 345000.0 0.49 925017.0 317000.0 0.44 0.6597 0.9987 2069616 Maybridge1_000478 Oc1ccc(CCc2nnc(S)n2c3cccc(c3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N17 compound treatment 972346.0 385000.0 0.55 940688.0 333000.0 0.46 0.7152 0.9966 1635176 Maybridge1_000479 COc1ccc(CN(Cc2ccccc2)C(=S)Nc3c(C)cccc3C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N18 compound treatment 949448.0 362000.0 0.51 932891.0 325000.0 0.45 0.6844 0.998 2069617 Maybridge1_000480 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N19 compound treatment 976535.0 389000.0 0.55 965588.0 358000.0 0.5 0.7439 0.9987 1041825 Maybridge1_000481 COC(=O)c1cccc([N+](=O)[O-])c1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N20 compound treatment 941459.0 354000.0 0.5 949634.0 342000.0 0.48 0.6929 0.9996 1733240 Maybridge1_000482 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N21 compound treatment 972454.0 385000.0 0.55 977653.0 370000.0 0.52 0.7517 0.9996 1669077 Maybridge1_000483 Cc1onc(c1C(=O)N2CCCc3cc(C)ccc23)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N22 compound treatment 934888.0 347000.0 0.49 944664.0 337000.0 0.47 0.6814 0.9997 2069618 Maybridge1_000484 CC1=NN(C(=O)C1)c2ccc(/N=C/c3ccc(Cl)c(Cl)c3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N23 mock treatment 961521.0 374000.0 0.53 964922.0 357000.0 0.5 0.7282 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 N24 mock treatment 708951.0 121000.0 0.17 741262.0 133000.0 0.19 0.2536 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O01 compound treatment 843236.0 256000.0 0.36 862635.0 255000.0 0.36 0.5083 0.9999 1915043 Maybridge1_000485 CCOC(=O)c1c(N)scc1c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O02 compound treatment 809848.0 222000.0 0.32 843405.0 236000.0 0.33 0.4558 0.9998 1150030 Maybridge1_000486 COc1ccccc1NC(=O)N2CCCN(CC2)C(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O03 compound treatment 864495.0 277000.0 0.39 900509.0 293000.0 0.41 0.5671 0.9998 2069619 Maybridge1_000487 c1csc(c1)c2csc(n2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O04 compound treatment 855594.0 268000.0 0.38 889812.0 282000.0 0.39 0.5476 0.9999 1324207 Maybridge1_000488 COc1ccccc1NC(=O)N2CCN(CC2)C(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O05 compound treatment 894213.0 307000.0 0.44 918585.0 311000.0 0.43 0.6148 1.0 1231382 Maybridge1_000489 OC1CCN(CC1)C(=S)NCCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O06 compound treatment 873015.0 285000.0 0.41 910349.0 302000.0 0.42 0.5853 0.9998 1249375 Maybridge1_000490 Fc1cccc(Cl)c1CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O07 compound treatment 888617.0 301000.0 0.43 960940.0 353000.0 0.49 0.6509 0.9976 2069620 Maybridge1_000491 OC(=O)CSCC(=O)NCCNc1nccc(n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O08 compound treatment 886032.0 298000.0 0.42 918847.0 311000.0 0.43 0.6068 0.9999 2069621 Maybridge1_000492 Brc1ccc(NC(=O)CN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O09 compound treatment 879600.0 292000.0 0.42 978385.0 371000.0 0.52 0.6591 0.9941 2069622 Maybridge1_000493 OCCN1CCN(CC1)c2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O10 compound treatment 868398.0 281000.0 0.4 899378.0 292000.0 0.41 0.5699 1.0 1549615 Maybridge1_000494 COc1ccc(CCNc2ncnc3scc(c4ccc(C)cc4)c23)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O11 compound treatment 911122.0 324000.0 0.46 958039.0 350000.0 0.49 0.6707 0.9996 2069623 Maybridge1_000495 FC(F)(F)c1ccnc(NCCNC(=O)c2ccccc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O12 compound treatment 850073.0 263000.0 0.37 882566.0 275000.0 0.38 0.5349 0.9999 2069624 Maybridge1_000496 FC(F)(F)c1cnc(NCCNC(=O)C2=Cc3cc(Cl)ccc3OC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O13 compound treatment 921654.0 334000.0 0.48 916318.0 308000.0 0.43 0.6401 0.9988 1702834 Maybridge1_000497 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCCN(Cc3ccc(Cl)cc3Cl)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O14 compound treatment 859302.0 272000.0 0.39 927051.0 319000.0 0.45 0.588 0.9975 2069625 Maybridge1_000498 CCCCCCCc1ccc(NC(=O)Nc2ccc(F)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O15 compound treatment 931918.0 344000.0 0.49 986846.0 379000.0 0.53 0.72 0.9993 1280161 Maybridge1_000499 CCCc1cnc(nc1)N2CCCN(CC2)C(=S)Nc3ccc(C)cc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O16 compound treatment 890214.0 303000.0 0.43 914055.0 306000.0 0.43 0.6063 1.0 2069626 Maybridge1_000500 Cc1ccccc1NC(=S)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O17 compound treatment 918219.0 331000.0 0.47 980730.0 373000.0 0.52 0.7002 0.9987 2069627 Maybridge1_000501 OC(=O)c1ccccc1C(=O)NCCNc2ccc(cn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O18 compound treatment 889272.0 302000.0 0.43 885132.0 277000.0 0.39 0.5768 0.9987 1569206 Maybridge1_000502 CCc1cc2c(cc1C(=O)CC3(O)C(=O)Nc4ccc(Br)cc43)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O19 compound treatment 909106.0 322000.0 0.46 964864.0 357000.0 0.5 0.6754 0.9991 2069628 Maybridge1_000503 CCOC(=O)c1c(N)sc(C)c1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O20 compound treatment 894843.0 307000.0 0.44 952473.0 345000.0 0.48 0.6488 0.9989 2069629 Maybridge1_000504 Oc1ccccc1/C=N/c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O21 compound treatment 945340.0 358000.0 0.51 977622.0 370000.0 0.52 0.7244 1.0 1609990 Maybridge1_000505 Clc1ccc(CN2CCCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O22 compound treatment 910419.0 323000.0 0.46 922384.0 315000.0 0.44 0.6348 0.9997 2069630 Maybridge1_000506 NNC(=O)c1sc2ccccc2c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O23 mock treatment 952914.0 365000.0 0.52 952538.0 345000.0 0.48 0.7073 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 O24 mock treatment 294876.0 -293000.0 -0.42 281402.0 -326000.0 -0.46 -0.6163 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P01 compound treatment 849826.0 262000.0 0.37 811270.0 203000.0 0.28 0.4643 0.9909 2069631 Maybridge1_000507 O=C(N/N=C/c1ccco1)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P02 compound treatment 886391.0 299000.0 0.42 810868.0 203000.0 0.28 0.5007 0.9805 2069632 Maybridge1_000508 Clc1c(sc2ccccc12)C(=O)SCC(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P03 compound treatment 863104.0 276000.0 0.39 812889.0 205000.0 0.29 0.4793 0.988 1982147 Maybridge1_000509 Cc1cc2CSC(SCc2cc1C)c3cc(Cl)cc(Cl)c3O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P04 compound treatment 867672.0 280000.0 0.4 828320.0 220000.0 0.31 0.4991 0.9918 2069633 Maybridge1_000510 COc1ccc(cc1)c2nnc(S)n2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P05 compound treatment 922023.0 334000.0 0.48 853870.0 246000.0 0.34 0.5789 0.9872 2069634 Maybridge1_000511 Cc1cc(C)c(/N=C/2\SC(=C)C3(CCCCC3)N2C(=O)c4c(Cl)sc5ccccc45)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P06 compound treatment 906716.0 319000.0 0.45 862125.0 254000.0 0.35 0.5717 0.9925 2069635 Maybridge1_000512 CCCCCCC(C)(SCC(=O)O)SCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P07 compound treatment 922701.0 335000.0 0.48 866357.0 258000.0 0.36 0.5919 0.9905 1444113 Maybridge1_000513 COc1ccccc1NC(=S)Nc2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P08 compound treatment 880819.0 293000.0 0.42 855807.0 248000.0 0.35 0.5394 0.9957 2069636 Maybridge1_000514 Cc1ccc2N(CCCc2c1)C(=S)Nc3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P09 compound treatment 921785.0 334000.0 0.48 871795.0 264000.0 0.37 0.5964 0.992 1715015 Maybridge1_000515 CCOC(=O)C1CCN(CC1)C(=S)Nc2cccc(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P10 compound treatment 888494.0 301000.0 0.43 852407.0 245000.0 0.34 0.5438 0.9937 2069637 Maybridge1_000516 CN(C)c1ccc(/C=N/NC(=O)CCc2ccc(O)cc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P11 compound treatment 978177.0 391000.0 0.56 906495.0 299000.0 0.42 0.6873 0.9899 2069638 Maybridge1_000517 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3[nH]cnc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P12 compound treatment 931720.0 344000.0 0.49 866606.0 259000.0 0.36 0.6012 0.9888 2069639 Maybridge1_000518 CS(=O)(=O)N1CCCc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P13 compound treatment 938193.0 351000.0 0.5 877266.0 269000.0 0.38 0.6183 0.9903 2069640 Maybridge1_000519 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P14 compound treatment 967950.0 380000.0 0.54 883430.0 276000.0 0.38 0.6543 0.986 1083099 Maybridge1_000520 CC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P15 compound treatment 954289.0 367000.0 0.52 880715.0 273000.0 0.38 0.6378 0.988 2069641 Maybridge1_000521 Brc1cccc(/C=N/Cc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P16 compound treatment 955375.0 368000.0 0.52 882091.0 274000.0 0.38 0.6403 0.9882 2069642 Maybridge1_000522 Cc1onc(c1NC(=O)NNC(=O)c2c(C)onc2c3ccccc3)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P17 compound treatment 967862.0 380000.0 0.54 905508.0 298000.0 0.42 0.6759 0.9915 1164239 Maybridge1_000523 COc1cc(CN(Cc2ccccc2)C(=S)Nc3c(C)cccc3C)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P18 compound treatment 956966.0 369000.0 0.53 896746.0 289000.0 0.4 0.6563 0.9914 1478744 Maybridge1_000524 Cc1ccc(NS(=O)(=O)C)cc1NC(=S)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P19 compound treatment 954753.0 367000.0 0.52 902782.0 295000.0 0.41 0.6601 0.993 2069643 Maybridge1_000525 Fc1ccc(/N=C/c2ccc3OCOc3c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P20 compound treatment 972238.0 385000.0 0.55 900997.0 293000.0 0.41 0.6759 0.9897 2069644 Maybridge1_000526 COCCCNC(=S)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P21 compound treatment 957234.0 370000.0 0.53 875373.0 268000.0 0.37 0.6355 0.9859 2069645 Maybridge1_000527 Cc1ccc(cc1Cl)N2C(SCC2=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P22 compound treatment 940177.0 353000.0 0.5 881977.0 274000.0 0.38 0.6249 0.991 2069646 Maybridge1_000528 COCCCNC(=S)Nc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P23 mock treatment 927541.0 340000.0 0.48 868165.0 260000.0 0.36 0.5986 0.99 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.542 P24 mock treatment 519376.0 -68200.0 -0.1 586330.0 -21500.0 -0.03 -0.0898 -0.8847 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A01 compound treatment 768647.0 187000.0 0.27 857623.0 234000.0 0.33 0.4189 0.9949 1349488 Maybridge1_000529 CCOC(=O)C1=C(C)N(C(=O)C1CC(=O)Nc2ccc(F)cc2)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A02 compound treatment 781083.0 200000.0 0.28 846111.0 222000.0 0.31 0.4201 0.999 2069647 Maybridge1_000530 FC(F)(F)c1cccc(NC(=S)N2CCCCC2CCN3CCOCC3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A03 compound treatment 846289.0 265000.0 0.38 861534.0 238000.0 0.33 0.5009 0.998 1364330 Maybridge1_000531 OC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A04 compound treatment 858874.0 277000.0 0.39 862827.0 239000.0 0.33 0.5148 0.9965 2069648 Maybridge1_000532 [O-][N+](=O)c1ccc2NC(NC(=O)c2c1)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A05 compound treatment 883365.0 302000.0 0.43 880121.0 256000.0 0.36 0.5565 0.9959 2069649 Maybridge1_000533 Clc1ccc(/C=N/N=C(\C(=O)c2ccccc2)/c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A06 compound treatment 913795.0 332000.0 0.47 892221.0 269000.0 0.37 0.599 0.9934 1933703 Maybridge1_000534 COc1ccc(CCNC(=O)c2ccc(cc2)[N+](=O)[O-])cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A07 compound treatment 912777.0 331000.0 0.47 905287.0 282000.0 0.39 0.6109 0.9959 1547043 Maybridge1_000535 Clc1c(sc2ccccc12)C(=O)Nc3ccc4[nH]nnc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A08 compound treatment 924859.0 343000.0 0.49 876374.0 253000.0 0.35 0.5945 0.9872 2069650 Maybridge1_000536 FC(F)(F)c1ccc(N2CCCCC2)c(NC=C(C#N)C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A09 compound treatment 920731.0 339000.0 0.48 876406.0 253000.0 0.35 0.5904 0.9881 1471479 Maybridge1_000537 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A10 compound treatment 944738.0 363000.0 0.52 924362.0 301000.0 0.42 0.6618 0.9946 1441228 Maybridge1_000538 COc1cc(CNc2cccc(F)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A11 compound treatment 962873.0 381000.0 0.54 914435.0 291000.0 0.41 0.6703 0.9897 1248791 Maybridge1_000539 Fc1ccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A12 compound treatment 956388.0 375000.0 0.53 913354.0 290000.0 0.4 0.6627 0.9906 1664786 Maybridge1_000540 CCOC(=O)c1c[nH]c2c(F)cccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A13 compound treatment 953385.0 372000.0 0.53 950579.0 327000.0 0.46 0.6964 0.9973 2069651 Maybridge1_000541 COc1cccc(C2SCc3cc(C)c(C)cc3CS2)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A14 compound treatment 994385.0 413000.0 0.59 914081.0 290000.0 0.4 0.7016 0.9835 2069652 Maybridge1_000542 COc1c(/N=C/c2cc(Br)ccc2O)c(C)c(/N=C/c3cc(Br)ccc3O)cc1C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A15 compound treatment 979487.0 398000.0 0.57 930724.0 307000.0 0.43 0.703 0.9905 2069653 Maybridge1_000543 COc1ccccc1/N=C\2/NC(C)(C)C(=C)S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A16 compound treatment 989453.0 408000.0 0.58 940835.0 317000.0 0.44 0.723 0.991 1304585 Maybridge1_000544 Clc1ccc(Cl)c(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A17 compound treatment 991476.0 410000.0 0.58 949010.0 325000.0 0.45 0.7331 0.9923 2069654 Maybridge1_000545 FC(F)(F)c1cc(NC(=O)c2cc3ccccc3oc2=O)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A18 compound treatment 954525.0 373000.0 0.53 935648.0 312000.0 0.44 0.6828 0.9951 2069655 Maybridge1_000546 [O-][N+](=O)c1ccc(C=C2C(=O)NC(=S)NC2=O)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A19 compound treatment 981179.0 400000.0 0.57 938786.0 315000.0 0.44 0.7127 0.9919 1673765 Maybridge1_000547 CC(=O)Nc1ccc(C)c(NC(=S)Nc2ccc(Cl)cc2C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A20 compound treatment 972533.0 391000.0 0.56 912525.0 289000.0 0.4 0.6781 0.9875 1676755 Maybridge1_000548 Cc1ncc(CSCC(=O)Nc2ccccc2F)c(CO)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A21 compound treatment 916631.0 335000.0 0.48 909526.0 286000.0 0.4 0.6189 0.9961 1714954 Maybridge1_000549 CC(C)c1ccc(cc1)N(CCc2ccccn2)C(=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A22 compound treatment 877171.0 296000.0 0.42 887768.0 264000.0 0.37 0.5578 0.9978 2069656 Maybridge1_000550 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A23 mock treatment 827618.0 246000.0 0.35 867072.0 243000.0 0.34 0.4875 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 A24 mock treatment 132654.0 -449000.0 -0.64 147888.0 -476000.0 -0.66 -0.9205 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B01 compound treatment 739084.0 158000.0 0.22 840645.0 217000.0 0.3 0.3725 0.9891 1706179 Maybridge1_000551 Clc1ccc(cc1Cl)C2N(Cc3ccccc3)CCC4CCCCN24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B02 compound treatment 736048.0 155000.0 0.22 871573.0 248000.0 0.35 0.3999 0.9761 2069657 Maybridge1_000552 [O-][N+](=O)c1cc(Cl)c(cc1N2CCCCC2)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B03 compound treatment 789301.0 208000.0 0.3 914452.0 291000.0 0.41 0.4957 0.9879 2069658 Maybridge1_000553 CCC(C(=O)NNC(=O)c1ccccc1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B04 compound treatment 812820.0 231000.0 0.33 922085.0 298000.0 0.42 0.5269 0.9932 1375753 Maybridge1_000554 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)Nc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B05 compound treatment 859954.0 279000.0 0.4 901762.0 278000.0 0.39 0.5543 0.9999 2069659 Maybridge1_000555 [O-][N+](=O)c1ccccc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B06 compound treatment 873686.0 292000.0 0.42 924973.0 301000.0 0.42 0.591 1.0 2069660 Maybridge1_000556 CC1(C)CCC(C)(C)N=C(N1)SCC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B07 compound treatment 891308.0 310000.0 0.44 963143.0 339000.0 0.47 0.6463 0.9994 2069661 Maybridge1_000557 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=S)Nc2cccc(Cl)c2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B08 compound treatment 852310.0 271000.0 0.39 925000.0 301000.0 0.42 0.5695 0.9991 2069662 Maybridge1_000558 Clc1ccc(cc1)S(=O)(=O)Nc2cccc(C#N)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B09 compound treatment 919696.0 338000.0 0.48 957983.0 334000.0 0.47 0.6698 0.9999 2069663 Maybridge1_000559 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(S)n2c3cccc(Cl)c3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B10 compound treatment 906614.0 325000.0 0.46 954110.0 330000.0 0.46 0.6528 1.0 2069664 Maybridge1_000560 Cc1cccc(C)c1NC(=O)CSC(=O)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B11 compound treatment 924689.0 343000.0 0.49 954101.0 330000.0 0.46 0.671 0.9996 2069665 Maybridge1_000561 OCc1ccc(N2CCOCC2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B12 compound treatment 885967.0 305000.0 0.43 929917.0 306000.0 0.43 0.6082 1.0 2069666 Maybridge1_000562 [O-][N+](=O)c1cccc(c1)c2noc(n2)c3c(F)cccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B13 compound treatment 936791.0 355000.0 0.51 976288.0 353000.0 0.49 0.705 0.9999 2069667 Maybridge1_000563 Cc1ccc(cc1)S(=O)(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B14 compound treatment 898891.0 317000.0 0.45 956114.0 332000.0 0.46 0.647 0.9999 2069668 Maybridge1_000564 Cc1cc(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B15 compound treatment 968950.0 387000.0 0.55 987552.0 364000.0 0.51 0.7485 0.9992 2069669 Maybridge1_000565 COC(=O)c1cc(ccc1n2cccc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B16 compound treatment 930499.0 349000.0 0.5 956757.0 333000.0 0.46 0.6794 0.9995 1590064 Maybridge1_000566 CC(C)(C#C)N1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B17 compound treatment 941028.0 360000.0 0.51 987874.0 364000.0 0.51 0.7207 1.0 2069670 Maybridge1_000567 Sc1nc2cc(Cl)c(Cl)cc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B18 compound treatment 847789.0 266000.0 0.38 929523.0 306000.0 0.43 0.5694 0.9982 2069671 Maybridge1_000568 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccc(Cl)cc2Sc3cc(Cl)ccc3OC(=O)c4ccc(cc4)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B19 compound treatment 934769.0 353000.0 0.5 958839.0 335000.0 0.47 0.6858 0.9993 2069672 Maybridge1_000569 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B20 compound treatment 871919.0 290000.0 0.41 899368.0 276000.0 0.38 0.5639 0.9994 2069673 Maybridge1_000570 NC(=O)c1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B21 compound treatment 873662.0 292000.0 0.42 968882.0 345000.0 0.48 0.6343 0.9973 2069674 Maybridge1_000571 Cc1ccc2cc(F)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B22 compound treatment 832627.0 251000.0 0.36 905552.0 282000.0 0.39 0.5305 0.9989 2069675 Maybridge1_000572 [O-][N+](=O)c1ccc(OC(=O)c2cccnc2Oc3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B23 mock treatment 785064.0 204000.0 0.29 918733.0 295000.0 0.41 0.4957 0.9852 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 B24 mock treatment 151870.0 -430000.0 -0.61 154416.0 -469000.0 -0.65 -0.8948 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C01 compound treatment 763337.0 182000.0 0.26 816815.0 193000.0 0.27 0.3733 0.9998 1663724 Maybridge1_000573 CCOC(=O)C1=C(CC(=O)Nc2ccc(OC)cc2)C(=O)N(C1C)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C02 compound treatment 767036.0 186000.0 0.26 818074.0 194000.0 0.27 0.3783 0.9999 1566478 Maybridge1_000574 CSc1cccc(NC(=S)N2CCCCC2CCN3CCOCC3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C03 compound treatment 807972.0 227000.0 0.32 904347.0 281000.0 0.39 0.5046 0.9953 1208608 Maybridge1_000575 Cc1cc(Cl)ccc1Nc2nnc(s2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C04 compound treatment 799098.0 218000.0 0.31 866613.0 243000.0 0.34 0.4584 0.999 2069676 Maybridge1_000576 Cc1ccccc1C(=O)N(c2nc3ccccc3s2)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C05 compound treatment 860727.0 279000.0 0.4 892833.0 269000.0 0.38 0.5462 0.9996 2069677 Maybridge1_000577 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3c(Cl)ccc(C)c3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C06 compound treatment 821862.0 240000.0 0.34 874715.0 251000.0 0.35 0.4893 0.9999 1323864 Maybridge1_000578 COc1ccc(CCNC(=O)c2c(Cl)cccc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C07 compound treatment 813402.0 232000.0 0.33 882187.0 258000.0 0.36 0.4882 0.999 1488891 Maybridge1_000579 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2c(C)onc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C08 compound treatment 871321.0 290000.0 0.41 887605.0 264000.0 0.37 0.5517 0.9984 1292706 Maybridge1_000580 COc1cc2CCNC(c3ccc(N)cc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C09 compound treatment 920634.0 339000.0 0.48 927104.0 303000.0 0.42 0.6403 0.9979 2069678 Maybridge1_000581 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(cc2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C10 compound treatment 877122.0 296000.0 0.42 912941.0 289000.0 0.4 0.5826 0.9998 2069679 Maybridge1_000582 COc1ccc(CCNc2ccc(cc2N)C(F)(F)F)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C11 compound treatment 906290.0 325000.0 0.46 921856.0 298000.0 0.42 0.6207 0.9986 2069680 Maybridge1_000583 Cc1ccc(cc1[N+](=O)[O-])C2=N/C(=C\c3cccs3)/C(=O)O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C12 compound treatment 873275.0 292000.0 0.41 884522.0 261000.0 0.36 0.5507 0.9978 2069681 Maybridge1_000584 Fc1ccc(cc1)c2cn3Cc4ccccc4Cc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C13 compound treatment 922745.0 341000.0 0.49 945839.0 322000.0 0.45 0.6609 0.9993 1396404 Maybridge1_000585 CC(=O)Nc1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C14 compound treatment 882485.0 301000.0 0.43 943264.0 320000.0 0.45 0.6179 0.9998 2069682 Maybridge1_000586 CCC(C(=O)Nc1ccc(cc1)C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C15 compound treatment 931416.0 350000.0 0.5 968921.0 345000.0 0.48 0.6924 0.9999 2069683 Maybridge1_000587 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)c(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C16 compound treatment 895981.0 315000.0 0.45 888045.0 264000.0 0.37 0.577 0.9954 2069684 Maybridge1_000588 FC(F)(F)c1cccc(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C17 compound treatment 914349.0 333000.0 0.47 926775.0 303000.0 0.42 0.6336 0.9984 2069685 Maybridge1_000589 CCOC(=O)C1CCN(CC1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C18 compound treatment 870371.0 289000.0 0.41 885880.0 262000.0 0.37 0.5491 0.9983 2069686 Maybridge1_000590 Cc1c(NNc2cc3c(c([N+](=O)[O-])c2C)C(C)(C)CC3(C)C)cc4c(c1[N+](=O)[O-])C(C)(C)CC4(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C19 compound treatment 913900.0 332000.0 0.47 936246.0 313000.0 0.44 0.6425 0.9992 1235622 Maybridge1_000591 CC(=O)Nc1ccc(C)c(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C20 compound treatment 871069.0 290000.0 0.41 905967.0 282000.0 0.39 0.5696 0.9997 2069687 Maybridge1_000592 [O-][N+](=O)c1ccc(/C=N/c2cc(ccc2N3CCOCC3)C(F)(F)F)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C21 compound treatment 903872.0 322000.0 0.46 918926.0 295000.0 0.41 0.6154 0.9986 2069688 Maybridge1_000593 Cc1ccc([N+](=O)[O-])c(c1)C(=O)N(CCc2ccccn2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C22 compound treatment 861718.0 280000.0 0.4 884563.0 261000.0 0.36 0.5391 0.999 1931746 Maybridge1_000594 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C23 mock treatment 847826.0 266000.0 0.38 897130.0 273000.0 0.38 0.5375 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 C24 mock treatment 165354.0 -416000.0 -0.59 149680.0 -474000.0 -0.66 -0.8859 -0.9985 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D01 compound treatment 850620.0 269000.0 0.38 871809.0 248000.0 0.35 0.5154 0.9987 1042344 Maybridge1_000595 [O-][N+](=O)c1ccccc1N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D02 compound treatment 789068.0 208000.0 0.3 922147.0 298000.0 0.42 0.5031 0.9858 2069689 Maybridge1_000596 [O-][N+](=O)c1cc(Cl)c(cc1N2CCOCC2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D03 compound treatment 887367.0 306000.0 0.44 962383.0 339000.0 0.47 0.6416 0.9992 1508813 Maybridge1_000597 CN1C(NC(=O)c2cc(Cl)ccc12)C3CCC=CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D04 compound treatment 862434.0 281000.0 0.4 964017.0 340000.0 0.47 0.6182 0.9963 2069690 Maybridge1_000598 CC(C)(C)NNC(=S)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D05 compound treatment 918218.0 337000.0 0.48 1014177.0 390000.0 0.54 0.7237 0.9979 2069691 Maybridge1_000599 N#Cc1cnn(c1n2cccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D06 compound treatment 908627.0 327000.0 0.47 1001990.0 378000.0 0.53 0.7021 0.998 1154273 Maybridge1_000600 Cc1ccc(NC(=O)c2c(F)cccc2Cl)c(c1)C(=O)Nc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D07 compound treatment 959781.0 378000.0 0.54 1028917.0 405000.0 0.57 0.7801 0.9997 2069692 Maybridge1_000601 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=S)Nc2cc(ccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D08 compound treatment 899544.0 318000.0 0.45 987965.0 364000.0 0.51 0.6791 0.9983 2069693 Maybridge1_000602 [O-][N+](=O)c1cc(ccc1N2CCCCC2)c3n[nH]c(=O)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D09 compound treatment 928014.0 347000.0 0.49 1058469.0 435000.0 0.61 0.7773 0.9947 2069694 Maybridge1_000603 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(S)n2c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D10 compound treatment 992730.0 411000.0 0.58 1035871.0 412000.0 0.57 0.82 1.0 2069695 Maybridge1_000604 COC(=O)C(C)SCC(=O)Nc1c(C)cccc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D11 compound treatment 964952.0 384000.0 0.55 1052136.0 428000.0 0.6 0.8082 0.999 2069696 Maybridge1_000605 Sc1nc2ccccc2c(=O)n1NC(=O)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D12 compound treatment 940304.0 359000.0 0.51 999211.0 376000.0 0.52 0.7312 0.9999 2069697 Maybridge1_000606 [O-][N+](=O)c1ccc(cc1)c2nc(no2)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D13 compound treatment 995709.0 414000.0 0.59 1017298.0 394000.0 0.55 0.8047 0.9994 2069698 Maybridge1_000607 Clc1ccc(cc1)c2noc(CCC(=O)NNS(=O)(=O)c3ccc(Cl)cc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D14 compound treatment 953922.0 372000.0 0.53 981558.0 358000.0 0.5 0.7275 0.9996 2069699 Maybridge1_000608 CC1CCC(C)(C)CN(C1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D15 compound treatment 1023519.0 442000.0 0.63 1055402.0 432000.0 0.6 0.8703 0.9998 2069700 Maybridge1_000609 N#Cc1cccc(c1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D16 compound treatment 988117.0 407000.0 0.58 1018885.0 395000.0 0.55 0.7987 0.9997 2069701 Maybridge1_000610 [O-][N+](=O)c1ccc(c(C#N)c1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D17 compound treatment 1029510.0 448000.0 0.64 1027931.0 404000.0 0.56 0.8492 0.9981 1031325 Maybridge1_000611 COc1ccccc1CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D18 compound treatment 952990.0 372000.0 0.53 991781.0 368000.0 0.51 0.7366 0.9999 1622063 Maybridge1_000612 Clc1ccc(OC(=O)c2cccs2)c(Sc3cc(Cl)ccc3OC(=O)c4cccs4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D19 compound treatment 972494.0 391000.0 0.56 1058827.0 435000.0 0.61 0.8223 0.999 2069702 Maybridge1_000613 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D20 compound treatment 953865.0 372000.0 0.53 989798.0 366000.0 0.51 0.7355 0.9998 1152323 Maybridge1_000614 Cc1cc(ccc1Cl)c2csc(N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D21 compound treatment 958315.0 377000.0 0.54 1012359.0 389000.0 0.54 0.7623 1.0 1111385 Maybridge1_000615 CCOC(=O)CNC(=O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D22 compound treatment 917389.0 336000.0 0.48 1007489.0 384000.0 0.54 0.7163 0.9984 1353468 Maybridge1_000616 COc1ccc(OC(=O)c2cccnc2Oc3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D23 mock treatment 959363.0 378000.0 0.54 992587.0 369000.0 0.51 0.7438 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 D24 mock treatment 118269.0 -463000.0 -0.66 141539.0 -482000.0 -0.67 -0.9413 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E01 compound treatment 862742.0 281000.0 0.4 914816.0 291000.0 0.41 0.57 1.0 1374907 Maybridge1_000617 CCOC(=O)C1=C(C)N(C(=O)C1CC(=O)Nc2ccc(cc2)C(=O)OCC)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E02 compound treatment 1826197.0 1240000.0 1.77 1856993.0 1230000.0 1.72 2.4679 0.9999 2069703 Maybridge1_000618 Oc1c(Cl)cc(Cl)cc1/C=C/2\SC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E03 compound treatment 931721.0 350000.0 0.5 997891.0 374000.0 0.52 0.7212 0.9997 2069704 Maybridge1_000619 Fc1ccc(Nc2nnc(s2)c3ccccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E04 compound treatment 896121.0 315000.0 0.45 995133.0 371000.0 0.52 0.6827 0.9973 1921741 Maybridge1_000620 [O-][N+](=O)c1cc(ccc1N2CCCCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E05 compound treatment 922536.0 341000.0 0.49 1032813.0 409000.0 0.57 0.7464 0.9967 1147994 Maybridge1_000621 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3cc(F)ccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E06 compound treatment 929479.0 348000.0 0.49 1015734.0 392000.0 0.55 0.7366 0.9988 2069705 Maybridge1_000622 [O-][N+](=O)c1cc(ccc1N2CCCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E07 compound treatment 972631.0 391000.0 0.56 1027092.0 403000.0 0.56 0.7912 1.0 1265948 Maybridge1_000623 Clc1cccc(NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E08 compound treatment 976082.0 395000.0 0.56 1057343.0 434000.0 0.6 0.8245 0.9993 1407219 Maybridge1_000624 COc1cc2CCN(C(c3cccc(C)c3)c2cc1OC)C(=O)c4sc5ccccc5c4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E09 compound treatment 997838.0 416000.0 0.59 1066583.0 443000.0 0.62 0.8555 0.9998 1372571 Maybridge1_000625 Cc1cccc(NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E10 compound treatment 976624.0 395000.0 0.56 1004324.0 381000.0 0.53 0.7727 0.9996 2069706 Maybridge1_000626 [O-][N+](=O)c1cc(ccc1NCCc2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E11 compound treatment 1610913.0 1030000.0 1.46 1319735.0 696000.0 0.97 1.7216 0.9801 2069707 Maybridge1_000627 CN(C)c1ccc(/C=C/2\N=C(OC2=O)c3ccc(C)c(c3)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E12 compound treatment 1002833.0 421000.0 0.6 1021526.0 398000.0 0.55 0.8161 0.9993 1239898 Maybridge1_000628 COc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCCCC3)c4ccc(Br)cc42 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E13 compound treatment 984110.0 403000.0 0.57 1021721.0 398000.0 0.56 0.7974 0.9999 2069708 Maybridge1_000629 Cc1onc(c1C(=O)Nc2ccc(C)c(c2)[N+](=O)[O-])c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E14 compound treatment 1004983.0 424000.0 0.6 1016568.0 393000.0 0.55 0.8133 0.9989 2069709 Maybridge1_000630 CCC(C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E15 compound treatment 1036583.0 455000.0 0.65 1088368.0 465000.0 0.65 0.9159 1.0 2069710 Maybridge1_000631 Cc1onc(c1C(=O)N(c2nc3ccccc3s2)c4cccc(Cl)c4)c5c(Cl)cccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E16 compound treatment 1003229.0 422000.0 0.6 1037073.0 413000.0 0.58 0.8318 0.9998 1278441 Maybridge1_000632 Cc1ccc(C)c(NC(=S)N(CCc2ccccc2)CCc3ccccn3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E17 compound treatment 1066334.0 485000.0 0.69 1103704.0 480000.0 0.67 0.961 0.9999 2069711 Maybridge1_000633 COc1cc(/C=C\2/SC(=S)NC2=O)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E18 compound treatment 998054.0 417000.0 0.59 1055010.0 431000.0 0.6 0.8443 1.0 2069712 Maybridge1_000634 [O-][N+](=O)c1ccc(s1)C2NC(=O)c3ccccc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E19 compound treatment 986865.0 405000.0 0.58 1035839.0 412000.0 0.57 0.8141 1.0 1046617 Maybridge1_000635 CC(=O)Nc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E20 compound treatment 1003552.0 422000.0 0.6 1024746.0 401000.0 0.56 0.82 0.9994 1935254 Maybridge1_000636 Cc1ccc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E21 compound treatment 1002989.0 422000.0 0.6 1006208.0 383000.0 0.53 0.8011 0.9983 2069713 Maybridge1_000637 CN(CCC#N)c1ccc(/C=N/CCC\N=C/c2ccc(cc2)N(C)CCC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E22 compound treatment 945848.0 364000.0 0.52 1041165.0 417000.0 0.58 0.7781 0.9983 1699144 Maybridge1_000638 CN(C)c1ccc(CC(C#N)c2ccc(N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E23 mock treatment 957592.0 376000.0 0.53 1043935.0 420000.0 0.59 0.7927 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 E24 mock treatment 168152.0 -413000.0 -0.59 149198.0 -475000.0 -0.66 -0.8836 -0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F01 compound treatment 855041.0 274000.0 0.39 896962.0 273000.0 0.38 0.5446 0.9999 1013657 Maybridge1_000639 [O-][N+](=O)c1ccccc1N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F02 compound treatment 895116.0 314000.0 0.45 917564.0 294000.0 0.41 0.6052 0.9991 1060533 Maybridge1_000640 COc1ccc(CCNC(=O)c2ccccc2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F03 compound treatment 849519.0 268000.0 0.38 989343.0 366000.0 0.51 0.6302 0.9897 1243303 Maybridge1_000641 Nc1ccccc1C(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F04 compound treatment 911870.0 330000.0 0.47 943621.0 320000.0 0.45 0.6478 0.9997 2069714 Maybridge1_000642 NC(=O)C(C1CCCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F05 compound treatment 951675.0 370000.0 0.53 975116.0 351000.0 0.49 0.7188 0.9994 2069715 Maybridge1_000643 N#CCc1nn(c(c1C#N)n2cccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F06 compound treatment 922271.0 341000.0 0.48 1016108.0 392000.0 0.55 0.7297 0.9982 2069716 Maybridge1_000644 FC(F)(F)c1cc(Br)ccc1NC(=O)C(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F07 compound treatment 961320.0 380000.0 0.54 1053594.0 430000.0 0.6 0.8059 0.9986 2069717 Maybridge1_000645 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2c(S)nnc2CCc3nc(no3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F08 compound treatment 929595.0 348000.0 0.5 1003364.0 380000.0 0.53 0.7245 0.9994 2069718 Maybridge1_000646 CN(C)c1ccc(cc1[N+](=O)[O-])c2n[nH]c(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F09 compound treatment 974514.0 393000.0 0.56 1067596.0 444000.0 0.62 0.833 0.9987 1003095 Maybridge1_000647 Oc1nc(O)c2ccccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F10 compound treatment 948403.0 367000.0 0.52 1033843.0 410000.0 0.57 0.7735 0.9989 2069719 Maybridge1_000648 [O-][N+](=O)c1cccc(c1)c2ncon2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F11 compound treatment 1003792.0 422000.0 0.6 1117486.0 494000.0 0.69 0.9117 0.9977 2069720 Maybridge1_000649 N#C/C(=C\c1ccc[nH]1)/c2nn(c(c2C#N)n3cccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F12 compound treatment 972836.0 391000.0 0.56 963113.0 339000.0 0.47 0.7283 0.9968 1572812 Maybridge1_000650 Cc1cc(Cl)cc2c(O)c(cnc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F13 compound treatment 1003063.0 422000.0 0.6 1018971.0 395000.0 0.55 0.8138 0.9991 2069721 Maybridge1_000651 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F14 compound treatment 977941.0 396000.0 0.56 998602.0 375000.0 0.52 0.7684 0.9993 2069722 Maybridge1_000652 CC1(CC2CC(C)(C)C1)CN2c3ccc(cc3[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F15 compound treatment 1001917.0 420000.0 0.6 1016493.0 393000.0 0.55 0.8102 0.999 2069723 Maybridge1_000653 Cn1c(S)nnc1c2ccc(o2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F16 compound treatment 960804.0 379000.0 0.54 1062499.0 439000.0 0.61 0.8142 0.998 2069724 Maybridge1_000654 N/C(=N\OC(=O)c1ccc(cc1)[N+](=O)[O-])/c2cccc(c2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F17 compound treatment 1020490.0 439000.0 0.62 1101941.0 478000.0 0.67 0.9131 0.9995 2069725 Maybridge1_000655 Cc1nc2c(Br)cc(Br)cc2c(=O)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F18 compound treatment 973877.0 392000.0 0.56 1039451.0 416000.0 0.58 0.8046 0.9998 2069726 Maybridge1_000656 [O-][N+](=O)c1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F19 compound treatment 958619.0 377000.0 0.54 1063352.0 440000.0 0.61 0.8129 0.9978 2069727 Maybridge1_000657 Cc1cc(C)c(NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F20 compound treatment 988957.0 408000.0 0.58 1021591.0 398000.0 0.55 0.8022 0.9998 2069728 Maybridge1_000658 COc1cc(/C=C(\C#N)/c2nn(c(c2C#N)n3cccc3)c4ccccc4)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F21 compound treatment 1032007.0 451000.0 0.64 1067491.0 444000.0 0.62 0.8907 0.9999 2069729 Maybridge1_000659 CCOC(=O)CNC(=O)c1c(OC)cccc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F22 compound treatment 931092.0 350000.0 0.5 1009575.0 386000.0 0.54 0.7321 0.9992 1547053 Maybridge1_000660 CCOC(=O)c1ccc(OC(=O)c2cccnc2Oc3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F23 mock treatment 959783.0 378000.0 0.54 1044070.0 420000.0 0.59 0.795 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 F24 mock treatment 150665.0 -431000.0 -0.61 170153.0 -454000.0 -0.63 -0.8805 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G01 compound treatment 867953.0 287000.0 0.41 898022.0 274000.0 0.38 0.5586 0.9995 2069730 Maybridge1_000661 Fc1ccc(NC(=S)NNC(=O)c2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G02 compound treatment 857883.0 276000.0 0.39 910830.0 287000.0 0.4 0.5611 1.0 2069731 Maybridge1_000662 Fc1cccc(/N=C/c2ccc(Cl)c(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G03 compound treatment 900308.0 319000.0 0.45 1006325.0 383000.0 0.53 0.698 0.9967 2069732 Maybridge1_000663 CCOC(=O)CCc1cc(/N=C/c2cc(Br)ccc2O)c(O)c(/N=C/c3cc(Br)ccc3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G04 compound treatment 903451.0 322000.0 0.46 967387.0 344000.0 0.48 0.6627 0.9997 2069733 Maybridge1_000664 [O-][N+](=O)c1cc(ccc1N2CCOCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G05 compound treatment 915938.0 334000.0 0.48 1001688.0 378000.0 0.53 0.7091 0.9987 2069734 Maybridge1_000665 Cc1cc(OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)n(n1)c4ccc(NC(=O)c5c(C)onc5c6c(Cl)cccc6Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G06 compound treatment 889468.0 308000.0 0.44 970079.0 346000.0 0.48 0.6513 0.9988 2069735 Maybridge1_000666 COc1cc2CCN=C(c3ccc(cc3)[N+](=O)[O-])c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G07 compound treatment 943436.0 362000.0 0.51 1013273.0 390000.0 0.54 0.7482 0.9996 1681606 Maybridge1_000667 Cc1nc2cc(Cl)ccc2c(=O)n1c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G08 compound treatment 930383.0 349000.0 0.5 978476.0 355000.0 0.49 0.7008 1.0 1649904 Maybridge1_000668 Fc1ccc(NC(=O)c2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G09 compound treatment 912172.0 331000.0 0.47 1027035.0 403000.0 0.56 0.7303 0.996 1446338 Maybridge1_000669 Cc1ccc(NC(=S)Nc2cccc(Cl)c2)cc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G10 compound treatment 915814.0 334000.0 0.48 967660.0 344000.0 0.48 0.6754 1.0 2069736 Maybridge1_000670 CC(Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G11 compound treatment 931864.0 350000.0 0.5 1007847.0 384000.0 0.54 0.7312 0.9993 2069737 Maybridge1_000671 CC1(C)N/C(=N/c2ccccc2Cl)/SC1=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G12 compound treatment 925339.0 344000.0 0.49 1003990.0 380000.0 0.53 0.7208 0.9992 1649200 Maybridge1_000672 Cc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCCCC3)c4ccc(Br)cc42 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G13 compound treatment 962067.0 381000.0 0.54 1003416.0 380000.0 0.53 0.7572 0.9999 1671135 Maybridge1_000673 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G14 compound treatment 965425.0 384000.0 0.55 970245.0 347000.0 0.48 0.7279 0.9981 2069738 Maybridge1_000674 COc1cc(CN(C(=O)c2cccc(c2)[N+](=O)[O-])c3cccc(F)c3)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G15 compound treatment 1004554.0 423000.0 0.6 1082654.0 459000.0 0.64 0.8781 0.9995 2069739 Maybridge1_000675 Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G16 compound treatment 971602.0 390000.0 0.55 1036650.0 413000.0 0.58 0.7996 0.9998 2069740 Maybridge1_000676 Fc1cccc(Cl)c1/C=C/2\SC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G17 compound treatment 1000880.0 419000.0 0.6 1073698.0 450000.0 0.63 0.8656 0.9997 1057803 Maybridge1_000677 Nc1nc2ccc(Cl)cc2c(c1C#N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G18 compound treatment 873157.0 292000.0 0.41 994028.0 370000.0 0.52 0.6585 0.9941 2069741 Maybridge1_000678 Cc1ccc(cc1[N+](=O)[O-])N2C(=O)CC(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G19 compound treatment 964662.0 383000.0 0.54 1049255.0 426000.0 0.59 0.805 0.9991 2069742 Maybridge1_000679 COc1cccc(/N=C/2\SC(=C)C(C)(C)N2C(=O)C(C3CCCC3)c4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G20 compound treatment 992954.0 412000.0 0.59 1010029.0 386000.0 0.54 0.7948 0.9991 2069743 Maybridge1_000680 [O-][N+](=O)c1ccc(s1)C2Nc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G21 compound treatment 860711.0 279000.0 0.4 1026468.0 403000.0 0.56 0.678 0.9856 2069744 Maybridge1_000681 COc1cc(CN2CCCN(Cc3cc(OC)c(OC)c(OC)c3)C2c4cc(Br)ccc4O)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G22 compound treatment 894809.0 313000.0 0.45 985777.0 362000.0 0.5 0.6722 0.9981 1014047 Maybridge1_000682 [O-][N+](=O)c1ccc(cc1)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G23 mock treatment 945839.0 364000.0 0.52 1015296.0 392000.0 0.55 0.7526 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 G24 mock treatment 146348.0 -435000.0 -0.62 152446.0 -471000.0 -0.66 -0.9023 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H01 compound treatment 873520.0 292000.0 0.42 881824.0 258000.0 0.36 0.5483 0.9975 2069745 Maybridge1_000683 Cc1onc(c1C(=O)SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H02 compound treatment 857357.0 276000.0 0.39 891875.0 268000.0 0.37 0.5419 0.9997 2069746 Maybridge1_000684 COc1cc2CCN(Cc2cc1OC)c3c(cc(cc3[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H03 compound treatment 886357.0 305000.0 0.43 975195.0 351000.0 0.49 0.6532 0.9981 1364884 Maybridge1_000685 COc1ccc(CCNC(=O)c2ccccc2N)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H04 compound treatment 884571.0 303000.0 0.43 953639.0 330000.0 0.46 0.6302 0.9995 2069747 Maybridge1_000686 [O-][N+](=O)c1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H05 compound treatment 903340.0 322000.0 0.46 957138.0 333000.0 0.47 0.6525 1.0 2069748 Maybridge1_000687 OC(C(=O)NNC(=S)Nc1cc(Cl)ccc1Cl)(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H06 compound treatment 851843.0 270000.0 0.38 948645.0 325000.0 0.45 0.5924 0.9967 2069749 Maybridge1_000688 [O-][N+](=O)c1cc(ccc1Oc2ccc(Cl)cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H07 compound treatment 903627.0 322000.0 0.46 989495.0 366000.0 0.51 0.6847 0.9986 2069750 Maybridge1_000689 Fc1ccccc1n2c(S)nnc2CCc3nc(no3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H08 compound treatment 888054.0 307000.0 0.44 991608.0 368000.0 0.51 0.6711 0.9967 2069751 Maybridge1_000690 N/C(=N\O)/c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H09 compound treatment 922410.0 341000.0 0.48 989374.0 366000.0 0.51 0.7035 0.9997 2069752 Maybridge1_000691 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)CSc2cc(OC)c(cc2OC)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H10 compound treatment 944941.0 363000.0 0.52 982017.0 358000.0 0.5 0.7189 0.9999 2069753 Maybridge1_000692 N/C(=N\OC(=O)c1c(Cl)cccc1Cl)/c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H11 compound treatment 955129.0 374000.0 0.53 994764.0 371000.0 0.52 0.7417 0.9999 2069754 Maybridge1_000693 [O-][N+](=O)c1cc(c(cc1N2CCCCC2)N3CCCCC3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H12 compound treatment 937373.0 356000.0 0.51 944313.0 321000.0 0.45 0.6741 0.9981 2069755 Maybridge1_000694 CN(NC(=O)C)c1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H13 compound treatment 943879.0 362000.0 0.52 1019305.0 396000.0 0.55 0.7546 0.9994 2069756 Maybridge1_000695 Clc1ccc(cc1)c2noc(CCC(=O)NNS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H14 compound treatment 983078.0 402000.0 0.57 967136.0 343000.0 0.48 0.7426 0.9962 2069757 Maybridge1_000696 [O-][N+](=O)c1cc(Cl)ccc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H15 compound treatment 1005265.0 424000.0 0.6 1030487.0 407000.0 0.57 0.8273 0.9995 1295661 Maybridge1_000697 Cc1cccnc1N2C(=O)C3C4CC(C=C4)C3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H16 compound treatment 952305.0 371000.0 0.53 1000422.0 377000.0 0.53 0.7444 1.0 2069758 Maybridge1_000698 CC(C)(C)c1ccc(OS(=O)(=O)c2ccc(Oc3c(Cl)cccc3[N+](=O)[O-])cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H17 compound treatment 1024137.0 443000.0 0.63 1037808.0 414000.0 0.58 0.8535 0.9991 2069759 Maybridge1_000699 Cc1nc2c(Br)cc(Br)cc2c(=O)n1c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H18 compound treatment 952332.0 371000.0 0.53 944960.0 321000.0 0.45 0.6898 0.9967 2069760 Maybridge1_000700 Nc1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H19 compound treatment 958287.0 377000.0 0.54 1004502.0 381000.0 0.53 0.7545 1.0 2069761 Maybridge1_000701 [O-][N+](=O)c1ccc(cc1)/C(=C/c2c(F)cccc2Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H20 compound treatment 843679.0 262000.0 0.37 983798.0 360000.0 0.5 0.6188 0.9893 2069762 Maybridge1_000702 Clc1ccc(/C=C(\C#N)/c2nn(c(c2C#N)n3cccc3)c4ccccc4)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H21 compound treatment 985646.0 404000.0 0.57 1005569.0 382000.0 0.53 0.783 0.9993 2069763 Maybridge1_000703 O=C1CCC(=O)N(N1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H22 compound treatment 942313.0 361000.0 0.51 970216.0 347000.0 0.48 0.7046 0.9996 2069764 Maybridge1_000704 O=C(NNC(=O)c1cccnc1Oc2ccccc2)c3cccnc3Oc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H23 mock treatment 955830.0 374000.0 0.53 1013772.0 390000.0 0.54 0.7612 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 H24 mock treatment 150550.0 -431000.0 -0.61 139423.0 -484000.0 -0.68 -0.9109 -0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I01 compound treatment 877505.0 296000.0 0.42 932251.0 309000.0 0.43 0.602 0.9999 2069765 Maybridge1_000705 COc1cccc(NC(=S)NNC(=O)c2ccccc2Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I02 compound treatment 855435.0 274000.0 0.39 950972.0 327000.0 0.46 0.5983 0.9969 1339133 Maybridge1_000706 Cc1ccc(cc1)S(=O)(=O)N2CN3CCN(C3)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I03 compound treatment 902571.0 321000.0 0.46 1024605.0 401000.0 0.56 0.7183 0.9949 2069766 Maybridge1_000707 CCOC(=O)CCc1cc(/N=C/c2cc(Cl)cc(Cl)c2O)c(O)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I04 compound treatment 936610.0 355000.0 0.51 1051772.0 428000.0 0.6 0.7793 0.9965 2069767 Maybridge1_000708 Oc1c(Cl)cc(Cl)cc1/C=N/c2cc(ccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I05 compound treatment 900267.0 319000.0 0.45 995143.0 371000.0 0.52 0.6869 0.9978 2069768 Maybridge1_000709 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I06 compound treatment 921865.0 340000.0 0.48 981290.0 358000.0 0.5 0.695 0.9999 1491155 Maybridge1_000710 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I07 compound treatment 985074.0 404000.0 0.57 1068375.0 445000.0 0.62 0.8444 0.9993 2069769 Maybridge1_000711 COc1cc(/C=N/N=C/c2cc(Br)ccc2O)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I08 compound treatment 926083.0 345000.0 0.49 990194.0 366000.0 0.51 0.708 0.9998 2069770 Maybridge1_000712 C/C=C(\C)/c1nc2c(Br)cc(Br)cc2c(=O)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I09 compound treatment 948816.0 367000.0 0.52 1038802.0 415000.0 0.58 0.7788 0.9987 1127116 Maybridge1_000713 Cc1ccc(NC(=S)Nc2ccccc2Cl)cc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I10 compound treatment 930266.0 349000.0 0.5 1050226.0 427000.0 0.59 0.7714 0.9959 2069771 Maybridge1_000714 Nc1cc(ccc1NCCc2ccccn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I11 compound treatment 941798.0 360000.0 0.51 1026325.0 403000.0 0.56 0.7594 0.999 2069772 Maybridge1_000715 Cc1cc(C)c(/N=C\2/NC(C)(C)C(=C)S2)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I12 compound treatment 939352.0 358000.0 0.51 1021580.0 398000.0 0.55 0.7523 0.9991 2069773 Maybridge1_000716 Oc1ccc(Br)cc1/C=N/c2cc(ccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I13 compound treatment 955886.0 374000.0 0.53 1013070.0 389000.0 0.54 0.7605 1.0 2069774 Maybridge1_000717 COc1ccc(NC(=S)NC(=O)c2ccccc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I14 compound treatment 977436.0 396000.0 0.56 1008638.0 385000.0 0.54 0.7778 0.9997 1116212 Maybridge1_000718 C(Cc1ccncc1)c2c[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I15 compound treatment 1001907.0 420000.0 0.6 1125879.0 502000.0 0.7 0.918 0.9969 2069775 Maybridge1_000719 CCOC(=O)c1ccc(NC(=O)CSc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I16 compound treatment 971534.0 390000.0 0.55 1056799.0 433000.0 0.6 0.8194 0.9991 2069776 Maybridge1_000720 Fc1cccc(Cl)c1C=C2C(=O)NC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I17 compound treatment 973249.0 392000.0 0.56 1076511.0 453000.0 0.63 0.8405 0.998 1949968 Maybridge1_000721 Fc1cccc(F)c1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I18 compound treatment 939425.0 358000.0 0.51 1036038.0 412000.0 0.58 0.7666 0.9982 2069777 Maybridge1_000722 CN1C(NC(=O)c2ccccc12)c3ccc(s3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I19 compound treatment 965087.0 384000.0 0.55 1041851.0 418000.0 0.58 0.7982 0.9994 2069778 Maybridge1_000723 Cc1ccc(NC(=O)c2ccccc2[N+](=O)[O-])c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I20 compound treatment 1008680.0 427000.0 0.61 1003156.0 379000.0 0.53 0.8038 0.9976 2069779 Maybridge1_000724 [O-][N+](=O)c1csc(c1)C2Nc3ccccc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I21 compound treatment 960278.0 379000.0 0.54 1082427.0 459000.0 0.64 0.8333 0.9963 2069780 Maybridge1_000725 COc1cc(cc(OC)c1OC)C2OC(=NN2C(=O)C)c3cc(C)ccc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I22 compound treatment 937438.0 356000.0 0.51 1045370.0 422000.0 0.59 0.7738 0.9972 2069781 Maybridge1_000726 Fc1cccc(F)c1C(=O)Nc2nnc(s2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I23 mock treatment 926686.0 345000.0 0.49 1057262.0 434000.0 0.6 0.7747 0.9947 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 I24 mock treatment 190259.0 -391000.0 -0.56 136761.0 -487000.0 -0.68 -0.8736 -0.9951 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J01 compound treatment 898072.0 317000.0 0.45 874010.0 250000.0 0.35 0.5652 0.9921 2069782 Maybridge1_000727 FC(F)(F)c1cc(NC(=O)CSC(=O)c2c(Cl)cccc2Cl)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J02 compound treatment 844541.0 263000.0 0.37 914835.0 291000.0 0.41 0.5517 0.9992 1367065 Maybridge1_000728 Cc1ccc2nc(NC(=O)C(C)(C)C)nc(O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J03 compound treatment 900694.0 319000.0 0.45 980014.0 356000.0 0.5 0.6724 0.999 2069783 Maybridge1_000729 Nc1nn(cc1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J04 compound treatment 896097.0 315000.0 0.45 935702.0 312000.0 0.44 0.6241 0.9999 2069784 Maybridge1_000730 CC(C)(C)NNC(=O)c1ccccc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J05 compound treatment 927772.0 346000.0 0.49 992046.0 368000.0 0.51 0.7115 0.9998 2069785 Maybridge1_000731 OC(C(=O)NNC(=S)Nc1ccc(F)cc1)(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J06 compound treatment 892239.0 311000.0 0.44 950261.0 327000.0 0.46 0.6346 0.9999 2069786 Maybridge1_000732 ClC(Cl)C(=O)Nc1cccc(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J07 compound treatment 941119.0 360000.0 0.51 987460.0 364000.0 0.51 0.7204 1.0 2069787 Maybridge1_000733 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=O)c2cccc(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J08 compound treatment 889394.0 308000.0 0.44 981538.0 358000.0 0.5 0.6626 0.9979 1550932 Maybridge1_000734 Clc1ccc(SCC(=O)Nc2cccc(C#N)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J09 compound treatment 955489.0 374000.0 0.53 1013891.0 390000.0 0.54 0.7609 0.9999 2069788 Maybridge1_000735 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNS(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J10 compound treatment 905653.0 324000.0 0.46 975144.0 351000.0 0.49 0.6726 0.9995 2069789 Maybridge1_000736 N/C(=N\OC(=O)c1sc2ccccc2c1Cl)/c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J11 compound treatment 953338.0 372000.0 0.53 1023009.0 399000.0 0.56 0.7678 0.9997 2069790 Maybridge1_000737 CSC1=NC(C)(C)CCC(C)(C)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J12 compound treatment 943556.0 362000.0 0.51 971270.0 348000.0 0.48 0.7069 0.9995 2069791 Maybridge1_000738 CN(NC(=O)C)c1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J13 compound treatment 924983.0 344000.0 0.49 974121.0 350000.0 0.49 0.691 1.0 2069792 Maybridge1_000739 Cc1ccc(cc1)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J14 compound treatment 898365.0 317000.0 0.45 969378.0 346000.0 0.48 0.6596 0.9994 1073582 Maybridge1_000740 [O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J15 compound treatment 969339.0 388000.0 0.55 1049129.0 425000.0 0.59 0.8096 0.9993 1272417 Maybridge1_000741 Cc1cccc(n1)N2C(=O)C3C4CC(C=C4)C3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J16 compound treatment 928495.0 347000.0 0.49 1018133.0 394000.0 0.55 0.738 0.9985 1535750 Maybridge1_000742 Nc1cccc(Cl)c1Oc2ccc(cc2)S(=O)(=O)Nc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J17 compound treatment 990265.0 409000.0 0.58 1038054.0 414000.0 0.58 0.8197 1.0 2069793 Maybridge1_000743 C/C(=N\N=C1NCCN1)/c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J18 compound treatment 947706.0 366000.0 0.52 995739.0 372000.0 0.52 0.7352 1.0 1727927 Maybridge1_000744 OC(=O)c1cccnc1Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J19 compound treatment 976378.0 395000.0 0.56 1014912.0 391000.0 0.55 0.7829 0.9999 2069794 Maybridge1_000745 Cc1ccc(cc1)/C(=C/c2cccs2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J20 compound treatment 898640.0 317000.0 0.45 953498.0 330000.0 0.46 0.6442 1.0 2069795 Maybridge1_000746 [O-][N+](=O)c1cc(ccc1Sc2nnc(c3cccs3)n2c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J21 compound treatment 994600.0 413000.0 0.59 986855.0 363000.0 0.51 0.7736 0.9973 2069796 Maybridge1_000747 CCN(CC)C(=S)Oc1c(Br)cc(Br)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J22 compound treatment 918987.0 338000.0 0.48 966216.0 343000.0 0.48 0.6772 1.0 2069797 Maybridge1_000748 CSC1=NCN(CN1)C(C)(C)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J23 mock treatment 976012.0 395000.0 0.56 1041661.0 418000.0 0.58 0.8089 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 J24 mock treatment 167942.0 -414000.0 -0.59 175685.0 -448000.0 -0.62 -0.8576 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K01 compound treatment 897471.0 316000.0 0.45 935240.0 312000.0 0.43 0.625 0.9999 1285576 Maybridge1_000749 O=c1oc2ccccc2cc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K02 compound treatment 861212.0 280000.0 0.4 951815.0 328000.0 0.46 0.6049 0.9976 2069798 Maybridge1_000750 FC(F)(F)c1cc(NC(=O)C(C2CCCC2)c3ccccc3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K03 compound treatment 871525.0 290000.0 0.41 966449.0 343000.0 0.48 0.6297 0.9973 1505255 Maybridge1_000751 CCN(Cc1cc(OC)c(OC)c(OC)c1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K04 compound treatment 877489.0 296000.0 0.42 962048.0 338000.0 0.47 0.6314 0.9984 2069799 Maybridge1_000752 Nc1cc(ccc1N2CCCCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K05 compound treatment 820926.0 239000.0 0.34 1017329.0 394000.0 0.55 0.629 0.9736 1366214 Maybridge1_000753 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K06 compound treatment 880337.0 299000.0 0.43 997590.0 374000.0 0.52 0.6693 0.9949 1452426 Maybridge1_000754 COc1ccc(CCNC(=O)c2c(C)onc2c3ccccc3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K07 compound treatment 916640.0 335000.0 0.48 994641.0 371000.0 0.52 0.7029 0.9992 2069800 Maybridge1_000755 CCOC(=O)c1ccc(/N=C/c2cc(Cl)cc(Cl)c2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K08 compound treatment 866778.0 285000.0 0.41 960517.0 337000.0 0.47 0.6191 0.9973 1462342 Maybridge1_000756 Cc1onc(c1C(=O)Nc2ccc3OCOCc3c2)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K09 compound treatment 940056.0 359000.0 0.51 1024116.0 400000.0 0.56 0.7555 0.999 1525441 Maybridge1_000757 COc1ccc(NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K10 compound treatment 920669.0 339000.0 0.48 1006292.0 383000.0 0.53 0.7184 0.9987 1633514 Maybridge1_000758 CCOC(=O)c1cnc2c(Cl)cc(Br)cc2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K11 compound treatment 908969.0 328000.0 0.47 1026284.0 403000.0 0.56 0.7264 0.9957 2069801 Maybridge1_000759 Cc1cc2CSC(SCc2cc1C)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K12 compound treatment 888192.0 307000.0 0.44 984672.0 361000.0 0.5 0.6644 0.9974 2069802 Maybridge1_000760 CCC(C(=O)NNC(=O)c1ccc(cc1)N(C)C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K13 compound treatment 920056.0 339000.0 0.48 992239.0 369000.0 0.51 0.7039 0.9995 2069803 Maybridge1_000761 Clc1cccc(Nc2nc3ccccc3s2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K14 compound treatment 891102.0 310000.0 0.44 1018274.0 395000.0 0.55 0.7005 0.9939 1035571 Maybridge1_000762 OC(=O)CCc1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K15 compound treatment 941771.0 360000.0 0.51 1038547.0 415000.0 0.58 0.7714 0.9982 1004900 Maybridge1_000763 CC(=O)Nc1ccccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K16 compound treatment 929560.0 348000.0 0.5 1003856.0 380000.0 0.53 0.725 0.9994 2069804 Maybridge1_000764 Cc1nc2ccc(Br)cc2c(=O)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K17 compound treatment 956151.0 375000.0 0.53 1073423.0 450000.0 0.63 0.8203 0.9967 2069805 Maybridge1_000765 Fc1cccc(F)c1C(=O)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K18 compound treatment 881101.0 300000.0 0.43 984741.0 361000.0 0.5 0.6574 0.9966 2069806 Maybridge1_000766 [O-][N+](=O)c1cc(ccc1SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K19 compound treatment 939262.0 358000.0 0.51 997931.0 374000.0 0.52 0.7289 0.9999 2069807 Maybridge1_000767 FC(F)(F)c1cc(Nc2nc3ccccc3s2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K20 compound treatment 853982.0 273000.0 0.39 925469.0 302000.0 0.42 0.5717 0.9992 2069808 Maybridge1_000768 [O-][N+](=O)c1ccc(s1)C2Nc3cc(ccc3O2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K21 compound treatment 979487.0 398000.0 0.57 1036640.0 413000.0 0.58 0.8075 1.0 2069809 Maybridge1_000769 Cc1ccc(cc1)S(=O)(=O)NNC(=S)NCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K22 compound treatment 891645.0 310000.0 0.44 980712.0 357000.0 0.5 0.664 0.9982 2069810 Maybridge1_000770 Cc1ccc(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K23 mock treatment 941147.0 360000.0 0.51 1031931.0 408000.0 0.57 0.7643 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 K24 mock treatment 158177.0 -423000.0 -0.6 158973.0 -465000.0 -0.65 -0.8839 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L01 compound treatment 858150.0 277000.0 0.39 864371.0 241000.0 0.34 0.5156 0.9969 1379387 Maybridge1_000771 Cc1nc2ccc(Br)cc2c(=O)n1c3ccccc3N4CCCCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L02 compound treatment 870159.0 289000.0 0.41 896547.0 273000.0 0.38 0.5594 0.9993 2069811 Maybridge1_000772 FC(F)(F)c1ccc(Cl)c(c1)C(=O)NNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L03 compound treatment 896846.0 315000.0 0.45 949859.0 326000.0 0.45 0.6388 1.0 2069812 Maybridge1_000773 CCOC(=O)CCc1nc(no1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L04 compound treatment 883972.0 303000.0 0.43 928434.0 305000.0 0.43 0.6047 1.0 2069813 Maybridge1_000774 Fc1cccc(Cl)c1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L05 compound treatment 904329.0 323000.0 0.46 944590.0 321000.0 0.45 0.6411 0.9999 2069814 Maybridge1_000775 Clc1cccc(c1)n2ncc(C#N)c2n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L06 compound treatment 896439.0 315000.0 0.45 923902.0 300000.0 0.42 0.6128 0.9994 2069815 Maybridge1_000776 Clc1cccc(Cl)c1C(=O)Nc2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L07 compound treatment 916144.0 335000.0 0.48 933108.0 309000.0 0.43 0.6417 0.9988 2069816 Maybridge1_000777 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NNC(=O)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L08 compound treatment 870976.0 290000.0 0.41 921794.0 298000.0 0.42 0.5851 1.0 1037133 Maybridge1_000778 [O-][N+](=O)c1cc(ccc1Oc2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L09 compound treatment 892073.0 311000.0 0.44 953441.0 330000.0 0.46 0.6375 0.9998 2069817 Maybridge1_000779 Oc1ccc(CCC(=O)NNC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L10 compound treatment 879969.0 299000.0 0.42 935693.0 312000.0 0.44 0.6079 0.9999 2069818 Maybridge1_000780 N/C(=N\OC(=O)c1ccc(cc1)[N+](=O)[O-])/c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L11 compound treatment 902537.0 321000.0 0.46 964768.0 341000.0 0.48 0.6592 0.9998 2069819 Maybridge1_000781 CCOC(=O)C1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L12 compound treatment 894686.0 313000.0 0.45 948841.0 325000.0 0.45 0.6356 1.0 2069820 Maybridge1_000782 Cc1cc(OC(=O)c2cccs2)c(Cl)c(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L13 compound treatment 917624.0 336000.0 0.48 967261.0 344000.0 0.48 0.6769 1.0 2069821 Maybridge1_000783 Cc1ccc(cc1)S(=O)(=O)c2ccccc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L14 compound treatment 929595.0 348000.0 0.5 960392.0 337000.0 0.47 0.6821 0.9997 2069822 Maybridge1_000784 OC(=O)c1ccccc1C(=O)c2ccc(Sc3ccc(Cl)cc3)c(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L15 compound treatment 950158.0 369000.0 0.52 988684.0 365000.0 0.51 0.7307 0.9999 1632645 Maybridge1_000785 Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L16 compound treatment 948552.0 367000.0 0.52 982147.0 358000.0 0.5 0.7226 0.9998 2090 Maybridge1_000786 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L17 compound treatment 966216.0 385000.0 0.55 982537.0 359000.0 0.5 0.7408 0.999 2069823 Maybridge1_000787 C/C(=N\N=C1NCCN1)/c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L18 compound treatment 906615.0 325000.0 0.46 953112.0 329000.0 0.46 0.6518 1.0 2069824 Maybridge1_000788 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Cl)cc2Sc3cc(Cl)ccc3OS(=O)(=O)c4ccc(C)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L19 compound treatment 938357.0 357000.0 0.51 1023031.0 399000.0 0.56 0.7527 0.9989 2069825 Maybridge1_000789 COc1cc(CCC(=O)NNC(=S)Nc2ccc(F)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L20 compound treatment 922447.0 341000.0 0.48 926864.0 303000.0 0.42 0.6419 0.9977 1250861 Maybridge1_000790 Fc1ccc(NC(=O)c2cccnc2Oc3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L21 compound treatment 971583.0 390000.0 0.55 1032482.0 409000.0 0.57 0.7954 0.9999 2069826 Maybridge1_000791 CCN(CC)C(=S)Oc1c(C)cc(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L22 compound treatment 864619.0 283000.0 0.4 991222.0 368000.0 0.51 0.6472 0.9929 1032648 Maybridge1_000792 CC(=O)COc1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L23 mock treatment 885569.0 304000.0 0.43 1019865.0 396000.0 0.55 0.6965 0.9927 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 L24 mock treatment 168738.0 -413000.0 -0.59 152090.0 -472000.0 -0.66 -0.8801 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M01 compound treatment 828236.0 247000.0 0.35 916623.0 293000.0 0.41 0.537 0.9971 1921024 Maybridge1_000793 FC(F)(F)c1cccc(NC(=O)c2ccc(Cl)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M02 compound treatment 825729.0 244000.0 0.35 946980.0 323000.0 0.45 0.5645 0.9917 2069827 Maybridge1_000794 [O-][N+](=O)c1ccc(cc1)C(=O)N(c2nc3ccccc3s2)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M03 compound treatment 883859.0 302000.0 0.43 978793.0 355000.0 0.5 0.6543 0.9975 2069828 Maybridge1_000795 CN(C)c1ccc(/C=N/N=C(\C(=O)c2ccccc2)/c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M04 compound treatment 868218.0 287000.0 0.41 999273.0 376000.0 0.52 0.6588 0.9923 2069829 Maybridge1_000796 Oc1c(Cl)cc(Cl)cc1/C=N/c2cc(ccc2N3CCOCC3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M05 compound treatment 891538.0 310000.0 0.44 1025486.0 402000.0 0.56 0.7081 0.993 1365502 Maybridge1_000797 Cc1onc(c1C(=O)Oc2cc(C)nc3ccc(F)cc23)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M06 compound treatment 857785.0 276000.0 0.39 970783.0 347000.0 0.48 0.6202 0.9946 2069830 Maybridge1_000798 FC(F)(F)c1ccc(N2CCCCC2)c(NC(=O)c3sc4ccccc4c3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M07 compound treatment 913881.0 332000.0 0.47 1029005.0 405000.0 0.57 0.734 0.996 1668985 Maybridge1_000799 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4ccc(Cl)c(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M08 compound treatment 860389.0 279000.0 0.4 919249.0 296000.0 0.41 0.572 0.9998 2069831 Maybridge1_000800 [O-][N+](=O)c1cc(ccc1NCc2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M09 compound treatment 889969.0 309000.0 0.44 1007669.0 384000.0 0.54 0.6889 0.9951 1516323 Maybridge1_000801 COc1ccccc1NC(=S)Nc2ccc(C)c(NS(=O)(=O)C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M10 compound treatment 923425.0 342000.0 0.49 987744.0 364000.0 0.51 0.7029 0.9998 2069832 Maybridge1_000802 FC(F)(F)c1cc(NC=C2C(=O)NC(=O)NC2=O)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M11 compound treatment 905364.0 324000.0 0.46 1049473.0 426000.0 0.59 0.7456 0.9921 2069833 Maybridge1_000803 Cc1cc2CSC(SCc2cc1C)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M12 compound treatment 870857.0 289000.0 0.41 979050.0 355000.0 0.5 0.6415 0.9957 2069834 Maybridge1_000804 Cc1c(Cl)cccc1NC(=S)Nc2cc3c(c([N+](=O)[O-])c2C)C(C)(C)CC3(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M13 compound treatment 898917.0 317000.0 0.45 1068044.0 444000.0 0.62 0.7574 0.9879 2069835 Maybridge1_000805 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M14 compound treatment 914522.0 333000.0 0.47 993464.0 370000.0 0.52 0.6996 0.9991 2069836 Maybridge1_000806 CCOC(=O)c1ccc(cc1)S(=O)(=O)NNC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M15 compound treatment 1056510.0 475000.0 0.68 1079495.0 456000.0 0.64 0.9272 0.9995 2069837 Maybridge1_000807 Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M16 compound treatment 887563.0 306000.0 0.44 986028.0 362000.0 0.51 0.6651 0.9972 1716824 Maybridge1_000808 COc1ccc(OC)c(CCC(=O)O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M17 compound treatment 938166.0 357000.0 0.51 1019382.0 396000.0 0.55 0.7489 0.9991 2069838 Maybridge1_000809 Cc1cc(/N=C/2\SC(=C)C(C)(C)N2C(=O)c3c(F)cccc3F)cc(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M18 compound treatment 1094496.0 513000.0 0.73 1065746.0 442000.0 0.62 0.9518 0.9965 2069839 Maybridge1_000810 COc1cc(/C=C(\C#N)/c2ccc(cc2)[N+](=O)[O-])cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M19 compound treatment 988260.0 407000.0 0.58 1072971.0 449000.0 0.63 0.8521 0.9992 2069840 Maybridge1_000811 Cc1ccc(NC(=O)c2ccccc2/N=C/c3cc(Cl)cc(Cl)c3O)c(/N=C/c4cc(Cl)cc(Cl)c4O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M20 compound treatment 869861.0 288000.0 0.41 997209.0 374000.0 0.52 0.6584 0.993 2069841 Maybridge1_000812 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M21 compound treatment 935086.0 354000.0 0.5 1019039.0 395000.0 0.55 0.7455 0.9989 2069842 Maybridge1_000813 COCCCNC(=S)NNS(=O)(=O)c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M22 compound treatment 899906.0 318000.0 0.45 994981.0 371000.0 0.52 0.6864 0.9978 2069843 Maybridge1_000814 [O-][N+](=O)c1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M23 mock treatment 934624.0 353000.0 0.5 1030928.0 407000.0 0.57 0.7567 0.9981 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 M24 mock treatment 762541.0 181000.0 0.26 778432.0 155000.0 0.22 0.3347 0.9961 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N01 compound treatment 886968.0 306000.0 0.43 893742.0 270000.0 0.38 0.5735 0.9975 2069844 Maybridge1_000815 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N02 compound treatment 805263.0 224000.0 0.32 898097.0 274000.0 0.38 0.4957 0.9958 1531991 Maybridge1_000816 COc1cc2CCN=C(c3ccccc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N03 compound treatment 886805.0 305000.0 0.43 963805.0 340000.0 0.47 0.6425 0.999 1510864 Maybridge1_000817 CC(NC(=O)c1ccccc1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N04 compound treatment 866077.0 285000.0 0.4 950653.0 327000.0 0.46 0.6086 0.9982 1610286 Maybridge1_000818 Cc1ccc2nc(oc(=O)c2c1)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N05 compound treatment 952388.0 371000.0 0.53 978078.0 354000.0 0.49 0.7225 0.9995 2069845 Maybridge1_000819 Cc1cccc(c1)C(=O)NNC(=O)CCc2nc(no2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N06 compound treatment 907040.0 326000.0 0.46 928245.0 305000.0 0.42 0.6277 0.9991 1684490 Maybridge1_000820 Fc1cccc(F)c1C(=O)Nc2cccc(C#N)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N07 compound treatment 925682.0 344000.0 0.49 982497.0 359000.0 0.5 0.7 0.9999 2069846 Maybridge1_000821 [O-][N+](=O)c1cc(ccc1NNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N08 compound treatment 896612.0 315000.0 0.45 959219.0 336000.0 0.47 0.6478 0.9998 1471855 Maybridge1_000822 CN(C)c1ccc(cc1N)c2n[nH]c(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N09 compound treatment 944091.0 363000.0 0.52 979397.0 356000.0 0.5 0.7154 0.9998 2069847 Maybridge1_000823 CNC(=S)NNC(=O)c1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N10 compound treatment 889100.0 308000.0 0.44 958866.0 335000.0 0.47 0.6399 0.9995 1933421 Maybridge1_000824 N/C(=N\OC(=O)c1cccs1)/c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N11 compound treatment 908294.0 327000.0 0.46 1001169.0 377000.0 0.53 0.7009 0.9981 1430952 Maybridge1_000825 Clc1ccc(cc1)c2noc(CCC(=O)Nc3cccc(Cl)c3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N12 compound treatment 913606.0 332000.0 0.47 945923.0 322000.0 0.45 0.6518 0.9997 2069848 Maybridge1_000826 Cc1cc(OC(=O)C(C2CCCC2)c3ccccc3)c(Cl)c(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N13 compound treatment 922288.0 341000.0 0.48 983238.0 360000.0 0.5 0.6973 0.9999 2069849 Maybridge1_000827 FC(F)(F)c1ccccc1S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N14 compound treatment 929827.0 348000.0 0.5 949709.0 326000.0 0.45 0.6718 0.9991 2069850 Maybridge1_000828 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])C(=O)c3ccccc3C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N15 compound treatment 905347.0 324000.0 0.46 982847.0 359000.0 0.5 0.6799 0.9991 2069851 Maybridge1_000829 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccc(Br)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N16 compound treatment 908944.0 327000.0 0.47 967825.0 344000.0 0.48 0.6687 0.9999 2069852 Maybridge1_000830 C/C(=N\O)/c1ccc(Cl)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N17 compound treatment 957270.0 376000.0 0.53 1010590.0 387000.0 0.54 0.7595 1.0 2069853 Maybridge1_000831 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N18 compound treatment 918174.0 337000.0 0.48 973944.0 350000.0 0.49 0.684 1.0 2069854 Maybridge1_000832 Cc1cc(ccc1Cl)C2=CSC3=NCCN23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N19 compound treatment 920433.0 339000.0 0.48 1034794.0 411000.0 0.57 0.7463 0.9963 1241971 Maybridge1_000833 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N20 compound treatment 938970.0 358000.0 0.51 1008101.0 384000.0 0.54 0.7386 0.9996 2069855 Maybridge1_000834 FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)c3cccnc3Oc4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N21 compound treatment 966584.0 385000.0 0.55 1027430.0 404000.0 0.56 0.7854 0.9999 1314785 Maybridge1_000835 O=C(Nc1ccccc1N2CCOCC2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N22 compound treatment 902647.0 321000.0 0.46 992954.0 369000.0 0.51 0.6871 0.9982 2069856 Maybridge1_000836 COc1cc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N23 mock treatment 922465.0 341000.0 0.48 997602.0 374000.0 0.52 0.7117 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 N24 mock treatment 738084.0 157000.0 0.22 666771.0 43100.0 0.06 0.2 0.8668 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O01 compound treatment 789248.0 208000.0 0.3 903044.0 279000.0 0.39 0.4844 0.9907 1345387 Maybridge1_000837 OC(=O)c1cc2cc(Br)ccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O02 compound treatment 784829.0 203000.0 0.29 915510.0 292000.0 0.41 0.4923 0.986 2069857 Maybridge1_000838 COc1cc(cc(OC)c1OC)C2NC(=O)c3cc(ccc3N2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O03 compound treatment 811904.0 230000.0 0.33 933964.0 310000.0 0.43 0.5377 0.9906 2069858 Maybridge1_000839 O=C(/C(=N\N=C\c1cccs1)/c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O04 compound treatment 811809.0 230000.0 0.33 951245.0 328000.0 0.46 0.5547 0.9867 1315297 Maybridge1_000840 COc1ccc(CCNC(=O)c2ccccc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O05 compound treatment 1002781.0 421000.0 0.6 1016001.0 392000.0 0.55 0.8106 0.999 2069859 Maybridge1_000841 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3OCOCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O06 compound treatment 821325.0 240000.0 0.34 911457.0 288000.0 0.4 0.525 0.9967 2069860 Maybridge1_000842 FC(F)(F)c1ccc(N2CCCC2)c(NC=C(C#N)C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O07 compound treatment 861610.0 280000.0 0.4 967523.0 344000.0 0.48 0.6208 0.9958 1573890 Maybridge1_000843 CCOC(=O)c1ccc(cc1)N2CC3CCCCN3C2c4cccc(OC)c4O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O08 compound treatment 861772.0 280000.0 0.4 949066.0 325000.0 0.45 0.6028 0.9979 1949137 Maybridge1_000844 CCOC(=O)C(=CNc1ccccc1F)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O09 compound treatment 884547.0 303000.0 0.43 1001472.0 378000.0 0.53 0.6773 0.995 1130032 Maybridge1_000845 Cc1c(Cl)cccc1NC(=S)Nc2ccc(Cl)cc2C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O10 compound treatment 862048.0 281000.0 0.4 953696.0 330000.0 0.46 0.6076 0.9975 2069861 Maybridge1_000846 FC(F)(F)c1cc(NC=C(C#N)C#N)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O11 compound treatment 859570.0 278000.0 0.4 983287.0 360000.0 0.5 0.6343 0.9931 2069862 Maybridge1_000847 CN(C)c1ccc(cc1)C2SCc3cc(C)c(C)cc3CS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O12 compound treatment 858508.0 277000.0 0.39 891283.0 268000.0 0.37 0.5425 0.9996 2069863 Maybridge1_000848 Clc1ccc(cc1)C2CN3C(=N2)C=Cc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O13 compound treatment 881285.0 300000.0 0.43 972337.0 349000.0 0.49 0.6453 0.9979 2069864 Maybridge1_000849 CC1(C)N/C(=N\c2cccc(c2)C(F)(F)F)/SC1=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O14 compound treatment 896263.0 315000.0 0.45 968746.0 345000.0 0.48 0.6568 0.9993 1186960 Maybridge1_000850 Cc1ccc(cc1)S(=O)(=O)NN2C(Nc3ccccc3C2=O)c4cc(Cl)cc(Cl)c4O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O15 compound treatment 906843.0 325000.0 0.46 982857.0 359000.0 0.5 0.6814 0.9992 1932406 Maybridge1_000851 FC(F)(F)c1ccccc1NC(=O)c2cc3ccccc3oc2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O16 compound treatment 840901.0 259000.0 0.37 988086.0 364000.0 0.51 0.6203 0.9876 2069865 Maybridge1_000852 [O-][N+](=O)c1ccc(C=C2C(=O)NC(=O)NC2=O)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O17 compound treatment 923514.0 342000.0 0.49 985979.0 362000.0 0.51 0.7012 0.9998 1041620 Maybridge1_000853 OC(=O)C(C1CCCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O18 compound treatment 904524.0 323000.0 0.46 1023249.0 400000.0 0.56 0.7189 0.9954 2069866 Maybridge1_000854 CN(C)c1ccc(/C=C(\C#N)/c2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O19 compound treatment 902225.0 321000.0 0.46 980911.0 357000.0 0.5 0.6748 0.999 2069867 Maybridge1_000855 FC(F)(F)c1cc(NCCC2CCCCN2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O20 compound treatment 864596.0 283000.0 0.4 993271.0 370000.0 0.52 0.6492 0.9925 2069868 Maybridge1_000856 Cc1ccc(cc1)S(=O)(=O)N/N=C/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O21 compound treatment 896013.0 315000.0 0.45 1024246.0 401000.0 0.56 0.7113 0.9939 2069869 Maybridge1_000857 FC(F)(F)c1cc(NC(=S)N2CCCCC2CCN3CCOCC3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O22 compound treatment 868070.0 287000.0 0.41 962844.0 339000.0 0.47 0.6227 0.9973 2069870 Maybridge1_000858 CC(=O)Nc1ccc(Br)cc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O23 mock treatment 883042.0 302000.0 0.43 987692.0 364000.0 0.51 0.6622 0.9965 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 O24 mock treatment 466926.0 -115000.0 -0.16 235511.0 -388000.0 -0.54 -0.498 -0.8808 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P01 compound treatment 785288.0 204000.0 0.29 858134.0 234000.0 0.33 0.4362 0.9982 2069871 Maybridge1_000859 CCOC(=O)C(=CNNS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P02 compound treatment 849026.0 268000.0 0.38 890699.0 267000.0 0.37 0.5324 0.9999 1214041 Maybridge1_000860 Cc1onc(c1C(=O)Nc2cccc3cccnc23)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P03 compound treatment 831380.0 250000.0 0.36 884360.0 261000.0 0.36 0.5084 0.9999 809283 Maybridge1_000861 NC(=O)c1cnn(c1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P04 compound treatment 853243.0 272000.0 0.39 885805.0 262000.0 0.37 0.5318 0.9996 2069872 Maybridge1_000862 ClC(Cl)(Cl)C(=O)Nc1cccc2cccnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P05 compound treatment 873987.0 293000.0 0.42 908175.0 284000.0 0.4 0.5747 0.9997 2069873 Maybridge1_000863 OC(c1nnc(S)n1c2ccc(F)cc2)(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P06 compound treatment 890937.0 309000.0 0.44 896313.0 273000.0 0.38 0.5801 0.9973 2069874 Maybridge1_000864 Cc1onc(c1C(=O)Nc2cccc(C#N)c2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P07 compound treatment 911579.0 330000.0 0.47 897554.0 274000.0 0.38 0.602 0.9948 2069875 Maybridge1_000865 CC(=O)c1c(O)nc2ccc(Cl)cc2c1c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P08 compound treatment 903002.0 322000.0 0.46 876692.0 253000.0 0.35 0.5728 0.9918 2069876 Maybridge1_000866 Cc1cccc(C)c1NC(=O)CSc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P09 compound treatment 916189.0 335000.0 0.48 882913.0 259000.0 0.36 0.5922 0.9908 2069877 Maybridge1_000867 COc1cc([N+](=O)[O-])c(OC)cc1SCc2nnc(o2)c3ccccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P10 compound treatment 885845.0 304000.0 0.43 892436.0 269000.0 0.37 0.5711 0.9974 2069878 Maybridge1_000868 [O-][N+](=O)c1ccc(N2CCCCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P11 compound treatment 909980.0 329000.0 0.47 892213.0 269000.0 0.37 0.5952 0.994 2069879 Maybridge1_000869 CCOC(=O)C1CCN(CC1)c2ccc(cc2N)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P12 compound treatment 916372.0 335000.0 0.48 902994.0 279000.0 0.39 0.6122 0.995 2069880 Maybridge1_000870 CN(NC(=O)c1ccncc1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P13 compound treatment 912836.0 331000.0 0.47 906520.0 283000.0 0.39 0.6121 0.9961 2069881 Maybridge1_000871 FC(F)(F)c1ccccc1S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P14 compound treatment 891975.0 311000.0 0.44 917495.0 294000.0 0.41 0.602 0.9993 2069882 Maybridge1_000872 Clc1ccc(SC(C(=O)c2ccc(Cl)cc2)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P15 compound treatment 904093.0 323000.0 0.46 909020.0 285000.0 0.4 0.6058 0.9975 2069883 Maybridge1_000873 Fc1ccccc1NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P16 compound treatment 923681.0 342000.0 0.49 880674.0 257000.0 0.36 0.5976 0.9887 2069884 Maybridge1_000874 COc1ccc(NC(=S)NCCSc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P17 compound treatment 917555.0 336000.0 0.48 940908.0 317000.0 0.44 0.6508 0.9993 2069885 Maybridge1_000875 C/C(=N\NC1=NCCN1Cc2ccccc2)/c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P18 compound treatment 925710.0 344000.0 0.49 943171.0 319000.0 0.45 0.6612 0.9989 2069886 Maybridge1_000876 N/C(=N\O)/c1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P19 compound treatment 930768.0 349000.0 0.5 931317.0 308000.0 0.43 0.6546 0.9973 2069887 Maybridge1_000877 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)CCc2cc(OC)c(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P20 compound treatment 923522.0 342000.0 0.49 926757.0 303000.0 0.42 0.6428 0.9975 2069888 Maybridge1_000878 Cc1ccc(SC(=O)c2cccnc2Oc3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P21 compound treatment 863436.0 282000.0 0.4 914124.0 290000.0 0.41 0.57 1.0 1389928 Maybridge1_000879 S=C1NCN(CCN2CCCC2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P22 compound treatment 887425.0 306000.0 0.44 933802.0 310000.0 0.43 0.6135 1.0 2069889 Maybridge1_000880 C/C(=N\O)/COc1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P23 mock treatment 840477.0 259000.0 0.37 902993.0 279000.0 0.39 0.5359 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.543 P24 mock treatment 220979.0 -360000.0 -0.51 586982.0 -36700.0 -0.05 -0.3987 -0.7739 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A01 compound treatment 885562.0 325000.0 0.46 807458.0 253000.0 0.35 0.5762 0.9913 2069890 Maybridge1_000881 Clc1cc(Cl)cc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A02 compound treatment 846652.0 286000.0 0.41 810262.0 256000.0 0.36 0.5399 0.998 2069891 Maybridge1_000882 Fc1cc2[nH]c(S)nc2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A03 compound treatment 867883.0 307000.0 0.44 793419.0 239000.0 0.33 0.5446 0.9913 1488119 Maybridge1_000883 Clc1ccc(cc1)C(=O)CNc2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A04 compound treatment 886123.0 325000.0 0.46 822457.0 268000.0 0.37 0.5916 0.9945 1497445 Maybridge1_000884 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A05 compound treatment 894337.0 333000.0 0.47 832125.0 278000.0 0.39 0.6094 0.995 1022907 Maybridge1_000885 CC(=O)c1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A06 compound treatment 905790.0 345000.0 0.49 868736.0 315000.0 0.44 0.657 0.9985 2069892 Maybridge1_000886 [O-][N+](=O)c1ccc(Oc2ccccc2F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A07 compound treatment 915571.0 355000.0 0.5 861618.0 308000.0 0.43 0.6598 0.9968 1472485 Maybridge1_000887 Cc1onc(c1C(=O)Nc2ccc(Br)cn2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A08 compound treatment 894271.0 333000.0 0.47 882219.0 328000.0 0.46 0.6587 0.9998 2069893 Maybridge1_000888 [O-][N+](=O)c1cc(Cl)ccc1Oc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A09 compound treatment 917755.0 357000.0 0.51 883058.0 329000.0 0.46 0.6831 0.9987 1619653 Maybridge1_000889 CC(=O)Nc1ccc(CC(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A10 compound treatment 914280.0 353000.0 0.5 884960.0 331000.0 0.46 0.6815 0.9991 1480482 Maybridge1_000890 CC(=O)Nc1c(F)cc(F)cc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A11 compound treatment 915328.0 354000.0 0.5 878679.0 325000.0 0.45 0.6764 0.9986 1657436 Maybridge1_000891 Clc1ccc(Cl)c(NC(=S)NCCc2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A12 compound treatment 902108.0 341000.0 0.49 855148.0 301000.0 0.42 0.6399 0.9974 2069894 Maybridge1_000892 [O-][N+](=O)c1cccnc1Sc2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A13 compound treatment 920073.0 359000.0 0.51 882026.0 328000.0 0.46 0.6845 0.9985 1208589 Maybridge1_000893 Cc1onc(c1C(=O)NCCc2ccncc2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A14 compound treatment 941477.0 380000.0 0.54 902074.0 348000.0 0.49 0.7258 0.9985 2069895 Maybridge1_000894 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)Nc3ccc(F)cc3F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A15 compound treatment 929578.0 369000.0 0.52 903390.0 349000.0 0.49 0.7151 0.9993 2069896 Maybridge1_000895 Clc1ccc2OC(=O)N(C(OC(=O)Nc3ccccc3)c2c1)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A16 compound treatment 945811.0 385000.0 0.55 892832.0 339000.0 0.47 0.721 0.9973 2069897 Maybridge1_000896 Cc1ccccc1C(=O)NCC(=O)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A17 compound treatment 943750.0 383000.0 0.54 876072.0 322000.0 0.45 0.7024 0.9954 2069898 Maybridge1_000897 Clc1ccc(SCc2ccc(cc2)c3nc4ccccc4s3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A18 compound treatment 922860.0 362000.0 0.51 859845.0 306000.0 0.43 0.6654 0.9956 1045890 Maybridge1_000898 COc1ccccc1Oc2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A19 compound treatment 902377.0 341000.0 0.49 846756.0 293000.0 0.41 0.6319 0.9963 2069899 Maybridge1_000899 CSC1=NCCN1C(=O)c2c(C)onc2c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A20 compound treatment 931693.0 371000.0 0.53 827477.0 273000.0 0.38 0.6423 0.9874 2069900 Maybridge1_000900 CC(C)(C)C(=O)Nc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A21 compound treatment 928308.0 367000.0 0.52 804592.0 251000.0 0.35 0.6164 0.9809 1250979 Maybridge1_000901 O=C(Nc1nccs1)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A22 compound treatment 891473.0 330000.0 0.47 781627.0 228000.0 0.32 0.5567 0.9817 1244212 Maybridge1_000902 Cn1sc(=O)c2cc(ccc12)S(=O)(=O)NC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A23 mock treatment 868187.0 307000.0 0.44 779487.0 225000.0 0.31 0.5312 0.987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 A24 mock treatment 161383.0 -400000.0 -0.57 146537.0 -408000.0 -0.57 -0.8038 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B01 compound treatment 849549.0 289000.0 0.41 765564.0 211000.0 0.29 0.4987 0.9869 1364313 Maybridge1_000903 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B02 compound treatment 850328.0 289000.0 0.41 775887.0 222000.0 0.31 0.5097 0.9901 2069901 Maybridge1_000904 Cc1cc(NC(=O)c2cccs2)c(cc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B03 compound treatment 891620.0 331000.0 0.47 822766.0 269000.0 0.37 0.5974 0.9937 2069902 Maybridge1_000905 CSC1=NCCN1CC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B04 compound treatment 866497.0 305000.0 0.43 816021.0 262000.0 0.37 0.5655 0.9963 1571188 Maybridge1_000906 Clc1ccc(Oc2ccccc2NC(=O)c3cccs3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B05 compound treatment 906673.0 346000.0 0.49 874818.0 321000.0 0.45 0.6639 0.9989 2069903 Maybridge1_000907 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CCCC3CCN(CC3)S(=O)(=O)c4cc(OC)ccc4OC)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B06 compound treatment 878112.0 317000.0 0.45 855268.0 301000.0 0.42 0.6159 0.9994 1632115 Maybridge1_000908 Clc1ccc(Oc2ccccc2NC(=O)NC(=O)c3c(Cl)cccc3Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B07 compound treatment 936773.0 376000.0 0.53 890511.0 336000.0 0.47 0.7096 0.9979 2069904 Maybridge1_000909 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2cccc(F)c2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B08 compound treatment 908883.0 348000.0 0.49 874232.0 320000.0 0.45 0.6655 0.9987 2069905 Maybridge1_000910 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2cc(Br)ccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B09 compound treatment 934679.0 374000.0 0.53 919434.0 365000.0 0.51 0.736 0.9998 2069906 Maybridge1_000911 CSC1=NCCN1CC(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B10 compound treatment 968377.0 407000.0 0.58 971426.0 417000.0 0.58 0.8212 1.0 2069907 Maybridge1_000912 COc1ccc(/C=C/2\SC(=S)NC2=O)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B11 compound treatment 907875.0 347000.0 0.49 934588.0 381000.0 0.53 0.724 0.9993 1295895 Maybridge1_000913 NNC(=O)CNC(=O)c1c(F)cccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B12 compound treatment 884198.0 323000.0 0.46 920906.0 367000.0 0.51 0.6867 0.9986 2069908 Maybridge1_000914 CN(C)/C=N/c1nnc(s1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B13 compound treatment 930248.0 369000.0 0.53 959239.0 405000.0 0.57 0.7708 0.9993 2069909 Maybridge1_000915 Brc1cc(cc(Br)c1n2cccc2)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B14 compound treatment 920353.0 359000.0 0.51 918384.0 364000.0 0.51 0.7206 1.0 1625161 Maybridge1_000916 Cc1ncc(COn2c(nc3ccccc3c2=O)c4ccccc4)c(CO)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B15 compound treatment 957982.0 397000.0 0.56 886667.0 333000.0 0.46 0.7272 0.9952 2069910 Maybridge1_000917 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3cccnc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B16 compound treatment 902596.0 342000.0 0.49 912405.0 358000.0 0.5 0.6968 0.9999 2069911 Maybridge1_000918 CC(C)(C)c1csc(Cc2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B17 compound treatment 968212.0 407000.0 0.58 920774.0 367000.0 0.51 0.7711 0.9981 2069912 Maybridge1_000919 COc1ccc(cc1OC)S(=O)(=O)NNc2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B18 compound treatment 915199.0 354000.0 0.5 867797.0 314000.0 0.44 0.6655 0.9975 1708614 Maybridge1_000920 Clc1cccc(Cl)c1C(=O)NC(=O)N2CCc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B19 compound treatment 930401.0 369000.0 0.53 902993.0 349000.0 0.49 0.7155 0.9993 2069913 Maybridge1_000921 Cc1ccc(NC(=S)Nc2ccc(C)c(C)c2)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B20 compound treatment 889486.0 328000.0 0.47 836566.0 282000.0 0.39 0.6089 0.9964 2069914 Maybridge1_000922 Clc1cccc(NC(=S)NN=C2CCCCCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B21 compound treatment 914834.0 354000.0 0.5 868812.0 315000.0 0.44 0.6662 0.9977 1545633 Maybridge1_000923 CC(=O)Nc1cc2cc(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)ccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B22 compound treatment 847121.0 286000.0 0.41 808052.0 254000.0 0.35 0.5381 0.9976 2069915 Maybridge1_000924 C/C(=N\NC(=S)N)/c1cc2cc(Cl)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B23 mock treatment 852302.0 291000.0 0.41 834448.0 280000.0 0.39 0.5694 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 B24 mock treatment 143362.0 -418000.0 -0.59 142566.0 -412000.0 -0.57 -0.8258 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C01 compound treatment 780540.0 220000.0 0.31 747604.0 194000.0 0.27 0.4116 0.9974 2069916 Maybridge1_000925 Cc1ccc(cc1)n2nnc(n2)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C02 compound treatment 788662.0 228000.0 0.32 738558.0 184000.0 0.26 0.4108 0.9935 1116479 Maybridge1_000926 On1c(nc2ccccc2c1=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C03 compound treatment 840776.0 280000.0 0.4 811584.0 258000.0 0.36 0.5353 0.9987 2069917 Maybridge1_000927 COc1ccc(cc1)c2c(C#N)c([nH]c(=O)c2C#N)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C04 compound treatment 1087496.0 526000.0 0.75 954450.0 400000.0 0.56 0.9242 0.9896 2069918 Maybridge1_000928 CC(C)(C)c1ccc(cc1)C(=O)N/N=C/c2cc(Cl)cc(Cl)c2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C05 compound treatment 845008.0 284000.0 0.4 780376.0 226000.0 0.32 0.5087 0.9926 1781213 Maybridge1_000929 CC(=O)Nc1cc2cc(ccc2oc1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C06 compound treatment 806998.0 246000.0 0.35 795779.0 242000.0 0.34 0.4857 0.9998 2069919 Maybridge1_000930 N#Cc1ccccc1N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C07 compound treatment 831165.0 270000.0 0.38 851602.0 298000.0 0.41 0.5651 0.9993 1019504 Maybridge1_000931 CCC(=O)c1ccc(cc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C08 compound treatment 837277.0 276000.0 0.39 845295.0 291000.0 0.41 0.565 0.9999 2069920 Maybridge1_000932 [O-][N+](=O)c1cc(ccc1Oc2c(Cl)cccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C09 compound treatment 856111.0 295000.0 0.42 864403.0 310000.0 0.43 0.6028 0.9999 2069921 Maybridge1_000933 [O-][N+](=O)c1ccc2oc(=O)c(NC(=O)c3c(F)cccc3F)cc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C10 compound treatment 870412.0 309000.0 0.44 880562.0 326000.0 0.46 0.6331 0.9999 2069922 Maybridge1_000934 CC(C)(C)NC(=S)N/N=C/c1ccccc1SC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C11 compound treatment 880289.0 319000.0 0.45 890034.0 336000.0 0.47 0.6524 0.9999 1708697 Maybridge1_000935 Cc1ccc(cc1)S(=O)(=O)NCCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C12 compound treatment 833965.0 273000.0 0.39 841172.0 287000.0 0.4 0.5576 0.9999 2069923 Maybridge1_000936 Cc1ccc(Sc2ncccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C13 compound treatment 835726.0 275000.0 0.39 871227.0 317000.0 0.44 0.589 0.9981 2069924 Maybridge1_000937 CCOC(=O)CNC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C14 compound treatment 853122.0 292000.0 0.42 854043.0 300000.0 0.42 0.5895 1.0 1019893 Maybridge1_000938 NCC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C15 compound treatment 898180.0 337000.0 0.48 922014.0 368000.0 0.51 0.7019 0.9994 2069925 Maybridge1_000939 Cc1nn(c(C)c1N=Nc2cc(Cl)cc(Cl)c2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C16 compound treatment 896522.0 335000.0 0.48 875421.0 321000.0 0.45 0.6543 0.9995 2069926 Maybridge1_000940 C/C(=N\NC(=S)NC(C)(C)C)/c1cc(F)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C17 compound treatment 874937.0 314000.0 0.45 880586.0 327000.0 0.46 0.6377 1.0 1556471 Maybridge1_000941 Clc1cccc(N2CCCCC2)c1C(C#N)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C18 compound treatment 806091.0 245000.0 0.35 812629.0 259000.0 0.36 0.5014 0.9999 2069927 Maybridge1_000942 NC(=S)NNC(=O)c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C19 compound treatment 844490.0 283000.0 0.4 831179.0 277000.0 0.39 0.5583 0.9998 2069928 Maybridge1_000943 CSC1=NCCN1C(=O)c2c(C)onc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C20 compound treatment 859976.0 299000.0 0.43 782666.0 229000.0 0.32 0.526 0.9899 2069929 Maybridge1_000944 CC(C)(C)C(=O)Nc1ccc(F)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C21 compound treatment 858431.0 297000.0 0.42 834787.0 281000.0 0.39 0.5759 0.9993 2069930 Maybridge1_000945 Cc1onc(c1C(=O)Nc2ccc(cc2Cl)[N+](=O)[O-])c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C22 compound treatment 807322.0 246000.0 0.35 776287.0 222000.0 0.31 0.4668 0.9981 2069931 Maybridge1_000946 Fc1cccc(Cl)c1CSC2=NCN(CN2)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C23 mock treatment 833303.0 272000.0 0.39 786061.0 232000.0 0.32 0.5026 0.996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 C24 mock treatment 155778.0 -405000.0 -0.58 141811.0 -412000.0 -0.57 -0.8141 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D01 compound treatment 879623.0 319000.0 0.45 812724.0 259000.0 0.36 0.5754 0.9936 2069932 Maybridge1_000947 COc1cc2CCN(C(C)c2cc1OC)C(=O)Nc3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D02 compound treatment 845029.0 284000.0 0.4 804189.0 250000.0 0.35 0.5322 0.9973 2069933 Maybridge1_000948 COC(OC)C(C)NC(=O)NC(=O)c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D03 compound treatment 869015.0 308000.0 0.44 837734.0 284000.0 0.4 0.5894 0.9987 2069934 Maybridge1_000949 COC(=O)/C=C/1\Nc2ccccc2C(=O)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D04 compound treatment 865821.0 305000.0 0.43 851197.0 297000.0 0.41 0.5995 0.9997 1544141 Maybridge1_000950 Fc1cccc(F)c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D05 compound treatment 878895.0 318000.0 0.45 899444.0 345000.0 0.48 0.6602 0.9995 2069935 Maybridge1_000951 Clc1ccccc1C(=O)NC(=O)Nc2cccc(C#C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D06 compound treatment 856156.0 295000.0 0.42 877816.0 324000.0 0.45 0.616 0.9993 1494826 Maybridge1_000952 Fc1cccc(F)c1C(=O)NC(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D07 compound treatment 915607.0 355000.0 0.5 963872.0 410000.0 0.57 0.7607 0.998 2069936 Maybridge1_000953 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D08 compound treatment 911165.0 350000.0 0.5 931208.0 377000.0 0.53 0.724 0.9996 2069937 Maybridge1_000954 CC(=O)c1cc(Cl)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D09 compound treatment 935829.0 375000.0 0.53 982328.0 428000.0 0.6 0.7992 0.9984 1666692 Maybridge1_000955 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccs3)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D10 compound treatment 914011.0 353000.0 0.5 961904.0 408000.0 0.57 0.7571 0.9981 2069938 Maybridge1_000956 [O-][N+](=O)c1ccc2oc3ncccc3c(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D11 compound treatment 924176.0 363000.0 0.52 982588.0 429000.0 0.6 0.7878 0.9974 2069939 Maybridge1_000957 CCC(C)(OC(=O)NC(=O)c1c(F)cccc1Cl)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D12 compound treatment 889698.0 329000.0 0.47 925558.0 371000.0 0.52 0.6968 0.9987 1099054 Maybridge1_000958 OC(=O)C1CSC(N1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D13 compound treatment 909475.0 348000.0 0.5 934145.0 380000.0 0.53 0.7252 0.9994 2069940 Maybridge1_000959 Clc1cc(Br)cc(Cl)c1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D14 compound treatment 895524.0 334000.0 0.48 947222.0 393000.0 0.55 0.7241 0.9975 1230634 Maybridge1_000960 Clc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D15 compound treatment 977880.0 417000.0 0.59 977326.0 423000.0 0.59 0.8366 1.0 2069941 Maybridge1_000961 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccccn3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D16 compound treatment 942516.0 381000.0 0.54 942874.0 389000.0 0.54 0.767 1.0 1172112 Maybridge1_000962 Cc1onc(c1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D17 compound treatment 991343.0 430000.0 0.61 968581.0 415000.0 0.58 0.8415 0.9996 2069942 Maybridge1_000963 COc1ccc(cc1OC)S(=O)(=O)N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D18 compound treatment 886246.0 325000.0 0.46 894412.0 340000.0 0.47 0.6627 0.9999 2069943 Maybridge1_000964 NNC(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D19 compound treatment 915805.0 355000.0 0.5 915762.0 362000.0 0.5 0.7134 1.0 1615615 Maybridge1_000965 Clc1ccc(NC(=S)NCCn2ccnc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D20 compound treatment 925443.0 364000.0 0.52 900408.0 346000.0 0.48 0.708 0.9994 2069944 Maybridge1_000966 Cc1ccc(CSc2nc(C(=O)C(F)(F)F)c3ccccn23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D21 compound treatment 934118.0 373000.0 0.53 899553.0 345000.0 0.48 0.7159 0.9988 2069945 Maybridge1_000967 CN(C)/C=N/C(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D22 compound treatment 888404.0 327000.0 0.47 850612.0 297000.0 0.41 0.6216 0.9983 2069946 Maybridge1_000968 N/C(=N\O)/CC(=O)Nc1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D23 mock treatment 939280.0 378000.0 0.54 861910.0 308000.0 0.43 0.6839 0.9938 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 D24 mock treatment 91750.0 -469000.0 -0.67 128149.0 -426000.0 -0.59 -0.8919 -0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E01 compound treatment 872368.0 311000.0 0.44 820473.0 266000.0 0.37 0.5758 0.9962 2069947 Maybridge1_000969 CC(C)(C)SCC(=O)Nc1cc(ccc1Oc2ccc(C#N)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E02 compound treatment 861673.0 301000.0 0.43 846215.0 292000.0 0.41 0.5904 0.9997 2069948 Maybridge1_000970 Fc1ccc(/N=C/c2c(F)cccc2Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E03 compound treatment 914332.0 353000.0 0.5 907133.0 353000.0 0.49 0.7034 0.9999 2069949 Maybridge1_000971 FC(F)(F)c1cc(NCC(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E04 compound treatment 918130.0 357000.0 0.51 888470.0 334000.0 0.47 0.6889 0.9991 2069950 Maybridge1_000972 [O-][N+](=O)c1ccc(Oc2ccc(cc2)c3ccccc3)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E05 compound treatment 949196.0 388000.0 0.55 861487.0 307000.0 0.43 0.6935 0.9922 1104647 Maybridge1_000973 Nc1c(C#N)cnn1CCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E06 compound treatment 913899.0 353000.0 0.5 939883.0 386000.0 0.54 0.7353 0.9994 1104603 Maybridge1_000974 NC(=O)c1ccccc1N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E07 compound treatment 924575.0 364000.0 0.52 952351.0 398000.0 0.56 0.7583 0.9994 1106751 Maybridge1_000975 Nc1cc2cc(ccc2oc1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E08 compound treatment 957326.0 396000.0 0.56 984059.0 430000.0 0.6 0.8225 0.9995 2069951 Maybridge1_000976 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E09 compound treatment 973868.0 413000.0 0.59 1044038.0 490000.0 0.68 0.8983 0.9971 1516140 Maybridge1_000977 CNc1ccccc1C(=O)NCCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E10 compound treatment 905059.0 344000.0 0.49 981089.0 427000.0 0.6 0.7671 0.9952 1122977 Maybridge1_000978 Cn1[nH]c(=O)c2cnc3c(F)cc(F)cc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E11 compound treatment 908370.0 347000.0 0.49 979229.0 425000.0 0.59 0.7686 0.9959 1967118 Maybridge1_000979 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCc2ccncc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E12 compound treatment 932539.0 372000.0 0.53 948433.0 394000.0 0.55 0.7625 0.9998 2069952 Maybridge1_000980 [O-][N+](=O)c1cccnc1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E13 compound treatment 935983.0 375000.0 0.53 1009934.0 456000.0 0.64 0.8266 0.9962 1352645 Maybridge1_000981 N#CC(N1CCOCC1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E14 compound treatment 926428.0 365000.0 0.52 961751.0 408000.0 0.57 0.7695 0.999 2069953 Maybridge1_000982 CC1CCN(CC1)S(=O)(=O)c2cc(Cl)c(Oc3ccc(cc3Cl)[N+](=O)[O-])c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E15 compound treatment 983798.0 423000.0 0.6 1041851.0 488000.0 0.68 0.9062 0.9981 1411187 Maybridge1_000983 CC(C)(C)NC(=O)NC(=O)c1c(F)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E16 compound treatment 950373.0 389000.0 0.55 979378.0 425000.0 0.59 0.8109 0.9994 1134663 Maybridge1_000984 Cc1onc(c1C(=O)NCC(=O)c2ccc(Br)cc2)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E17 compound treatment 998767.0 438000.0 0.62 987268.0 433000.0 0.6 0.8674 0.9999 2069954 Maybridge1_000985 COC(=O)c1nn(nc1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E18 compound treatment 922005.0 361000.0 0.51 902512.0 348000.0 0.49 0.7066 0.9996 2069955 Maybridge1_000986 Fc1ccc(NC(=O)CS(=O)(=O)Cc2ccc(Cl)c(Cl)c2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E19 compound treatment 910563.0 350000.0 0.5 928718.0 375000.0 0.52 0.7209 0.9997 2069956 Maybridge1_000987 CSC1=NCCN1C(=O)c2c(C)onc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E20 compound treatment 928104.0 367000.0 0.52 912292.0 358000.0 0.5 0.7224 0.9998 2069957 Maybridge1_000988 C/C(=N\O)/c1cc2ccccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E21 compound treatment 956302.0 395000.0 0.56 928567.0 374000.0 0.52 0.7668 0.9993 2069958 Maybridge1_000989 CC(=O)Nc1cc(Sc2ccc(Cl)cc2)c(F)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E22 compound treatment 916283.0 355000.0 0.51 883915.0 330000.0 0.46 0.6825 0.9989 2069959 Maybridge1_000990 N#Cc1cccc(CSC2=NCN(CN2)C3CC3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E23 mock treatment 959438.0 398000.0 0.57 890256.0 336000.0 0.47 0.7322 0.9956 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 E24 mock treatment 158984.0 -402000.0 -0.57 144431.0 -410000.0 -0.57 -0.8083 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F01 compound treatment 865378.0 304000.0 0.43 848579.0 295000.0 0.41 0.5965 0.9997 1593780 Maybridge1_000991 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F02 compound treatment 880417.0 319000.0 0.45 817404.0 263000.0 0.37 0.5809 0.9944 2069960 Maybridge1_000992 Cc1cc(NC(=O)c2ccc(F)cc2)c(cc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F03 compound treatment 923372.0 362000.0 0.52 892304.0 338000.0 0.47 0.6979 0.999 2069961 Maybridge1_000993 COc1ccccc1Oc2ccc(cc2NC(=O)c3ccc(Cl)cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F04 compound treatment 896987.0 336000.0 0.48 876677.0 323000.0 0.45 0.656 0.9996 2069962 Maybridge1_000994 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F05 compound treatment 934317.0 373000.0 0.53 963181.0 409000.0 0.57 0.7788 0.9993 2069963 Maybridge1_000995 Fc1cccc(F)c1C(=O)NC(=O)Nc2cccc(C#C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F06 compound treatment 923443.0 362000.0 0.52 952322.0 398000.0 0.56 0.7572 0.9993 1339372 Maybridge1_000996 Fc1cccc(Cl)c1C(=O)NC(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F07 compound treatment 985807.0 425000.0 0.6 1009913.0 456000.0 0.64 0.8767 0.9997 2069964 Maybridge1_000997 CN(NC(=O)NC(=O)c1c(Cl)cccc1Cl)c2ccc(Cl)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F08 compound treatment 965947.0 405000.0 0.58 1002323.0 448000.0 0.63 0.8492 0.9992 2069965 Maybridge1_000998 CC(=O)c1cc(F)cc(Cl)c1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F09 compound treatment 954997.0 394000.0 0.56 1038313.0 484000.0 0.68 0.8737 0.9957 2069966 Maybridge1_000999 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccc(c3)C(F)(F)F)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F10 compound treatment 992076.0 431000.0 0.61 1088439.0 534000.0 0.75 0.9604 0.9953 2069967 Maybridge1_001000 CCOc1ccc(Br)cc1/C=C/2\SC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F11 compound treatment 950318.0 389000.0 0.55 1021418.0 467000.0 0.65 0.8523 0.9967 2069968 Maybridge1_001001 CCCc1ccc(NC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F12 compound treatment 918113.0 357000.0 0.51 995903.0 442000.0 0.62 0.7948 0.9954 2069969 Maybridge1_001002 COc1cccc2sc(/N=C/N(C)C)nc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F13 compound treatment 914478.0 353000.0 0.5 977167.0 423000.0 0.59 0.7727 0.9968 2069970 Maybridge1_001003 Brc1ccc(NC(=O)CSc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F14 compound treatment 913882.0 353000.0 0.5 983878.0 430000.0 0.6 0.7787 0.9961 1281600 Maybridge1_001004 COC(=O)c1ccc(Cl)cc1NC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F15 compound treatment 935158.0 374000.0 0.53 1027931.0 474000.0 0.66 0.8435 0.9942 2069971 Maybridge1_001005 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccncc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F16 compound treatment 927576.0 367000.0 0.52 991801.0 438000.0 0.61 0.8003 0.9969 2069972 Maybridge1_001006 Brc1ccc(COc2ccc(cc2)S(=O)(=O)c3ccc(OCc4ccc(Br)cc4)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F17 compound treatment 976713.0 416000.0 0.59 975689.0 422000.0 0.59 0.8338 1.0 2069973 Maybridge1_001007 CN(C)/C=N/C(=S)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F18 compound treatment 885480.0 324000.0 0.46 917947.0 364000.0 0.51 0.6851 0.9989 2069974 Maybridge1_001008 NNC(=S)Nc1cc(ccc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F19 compound treatment 930276.0 369000.0 0.53 955971.0 402000.0 0.56 0.7676 0.9995 2069975 Maybridge1_001009 Clc1ccc(Cl)c(NC(=S)NCCCn2ccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F20 compound treatment 948739.0 388000.0 0.55 910031.0 356000.0 0.5 0.7409 0.9986 2069976 Maybridge1_001010 FC(F)(F)c1ccc(Cl)c(NC(=S)NN=C2CCCCCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F21 compound treatment 978703.0 418000.0 0.59 946990.0 393000.0 0.55 0.8075 0.9992 2069977 Maybridge1_001011 CSc1cccc(NC(=S)/N=C/N(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F22 compound treatment 855571.0 295000.0 0.42 852128.0 298000.0 0.42 0.5901 1.0 2069978 Maybridge1_001012 Clc1ccc(OCOc2ccc(Cl)cc2Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F23 mock treatment 945211.0 384000.0 0.55 889878.0 336000.0 0.47 0.7175 0.9971 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 F24 mock treatment 124105.0 -437000.0 -0.62 135336.0 -419000.0 -0.58 -0.8523 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G01 compound treatment 853386.0 292000.0 0.42 833317.0 279000.0 0.39 0.5694 0.9995 2069979 Maybridge1_001013 O=c1s[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G02 compound treatment 849124.0 288000.0 0.41 832756.0 279000.0 0.39 0.5645 0.9997 1483646 Maybridge1_001014 Fc1cccc2nc(oc(=O)c12)C(C3CCCC3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G03 compound treatment 884629.0 324000.0 0.46 889821.0 336000.0 0.47 0.6565 1.0 1722347 Maybridge1_001015 COc1cc(cc(OC)c1OC)c2c(C#N)c(OC)[nH]c(=O)c2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G04 compound treatment 885504.0 324000.0 0.46 894719.0 341000.0 0.48 0.6622 0.9999 1136768 Maybridge1_001016 Nc1ccc(Oc2ccc(Cl)cc2Cl)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G05 compound treatment 887302.0 326000.0 0.46 914851.0 361000.0 0.5 0.6839 0.9992 2069980 Maybridge1_001017 CC(C)NC(=O)N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G06 compound treatment 847402.0 286000.0 0.41 944636.0 391000.0 0.54 0.6731 0.9897 2069981 Maybridge1_001018 Cc1ccc(cc1)C(=O)CSC(=S)SC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G07 compound treatment 884668.0 324000.0 0.46 975667.0 422000.0 0.59 0.7412 0.9927 2069982 Maybridge1_001019 FC(F)(F)c1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G08 compound treatment 900637.0 340000.0 0.48 995687.0 442000.0 0.62 0.777 0.9928 2069983 Maybridge1_001020 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)c(Cl)c1Oc3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G09 compound treatment 936582.0 376000.0 0.53 1001700.0 448000.0 0.62 0.8191 0.997 1698854 Maybridge1_001021 Fc1cccc(F)c1C(=O)NC(=O)NCCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G10 compound treatment 884709.0 324000.0 0.46 990326.0 436000.0 0.61 0.7557 0.9905 2069984 Maybridge1_001022 FC(F)(F)c1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G11 compound treatment 895523.0 334000.0 0.48 933307.0 379000.0 0.53 0.7103 0.9986 1033716 Maybridge1_001023 CC(=O)Nc1ccc(F)cc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G12 compound treatment 856453.0 295000.0 0.42 937000.0 383000.0 0.53 0.6747 0.9929 2069985 Maybridge1_001024 [O-][N+](=O)c1cccnc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G13 compound treatment 919067.0 358000.0 0.51 994723.0 441000.0 0.61 0.7946 0.9956 2069986 Maybridge1_001025 CCOC(=O)CCC(C#N)(N1CCOCC1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G14 compound treatment 868946.0 308000.0 0.44 958514.0 404000.0 0.56 0.7085 0.9922 2069987 Maybridge1_001026 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCCCC3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G15 compound treatment 957679.0 397000.0 0.56 1022619.0 469000.0 0.65 0.8609 0.9973 1716717 Maybridge1_001027 Fc1cccc(Cl)c1C(=O)NC(=O)Nc2ccccc2N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G16 compound treatment 907637.0 347000.0 0.49 982717.0 429000.0 0.6 0.7713 0.9954 2069988 Maybridge1_001028 COc1ccccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G17 compound treatment 977919.0 417000.0 0.59 968581.0 415000.0 0.58 0.828 0.9999 2069989 Maybridge1_001029 Cc1nn(nc1C(=O)N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G18 compound treatment 885163.0 324000.0 0.46 914539.0 360000.0 0.5 0.6814 0.9991 2069990 Maybridge1_001030 N/C(=N\O)/c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G19 compound treatment 934001.0 373000.0 0.53 979318.0 425000.0 0.59 0.7944 0.9984 2069991 Maybridge1_001031 CSC1=NCCCN1C(=O)c2c(C)onc2c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G20 compound treatment 876757.0 316000.0 0.45 877561.0 323000.0 0.45 0.6365 1.0 1190516 Maybridge1_001032 COc1ccc(c2c(C)n[nH]c2C)c(c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G21 compound treatment 899629.0 339000.0 0.48 843223.0 289000.0 0.4 0.6256 0.9961 1072508 Maybridge1_001033 Brc1ccc(cc1)C(=O)CSCC(=O)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G22 compound treatment 864472.0 303000.0 0.43 861433.0 307000.0 0.43 0.6082 1.0 2069992 Maybridge1_001034 CCC1(CC)N/C(=N/c2cc(Cl)cc(Cl)c2)/SC1=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G23 mock treatment 929300.0 368000.0 0.52 879952.0 326000.0 0.45 0.6917 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 G24 mock treatment 160493.0 -401000.0 -0.57 130559.0 -424000.0 -0.59 -0.8204 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H01 compound treatment 856050.0 295000.0 0.42 831358.0 277000.0 0.39 0.5701 0.9992 1541940 Maybridge1_001035 COc1ccc(OC)c(c1)S(=O)(=O)N2CCc3cc(OC)c(OC)cc3C2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H02 compound treatment 852671.0 292000.0 0.41 762572.0 208000.0 0.29 0.4989 0.9849 2069993 Maybridge1_001036 Cc1onc(c1C(=O)Nc2cc(C)c(C)cc2[N+](=O)[O-])c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H03 compound treatment 909243.0 348000.0 0.5 867789.0 314000.0 0.44 0.6595 0.9981 2069994 Maybridge1_001037 COc1ccccc1Oc2ccc(cc2NC(=O)NC(=O)c3ccccc3F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H04 compound treatment 891266.0 330000.0 0.47 857167.0 303000.0 0.42 0.631 0.9986 1249841 Maybridge1_001038 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H05 compound treatment 930267.0 369000.0 0.53 933721.0 380000.0 0.53 0.7457 1.0 1681763 Maybridge1_001039 Clc1ccccc1C(=O)NC(=O)N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H06 compound treatment 881486.0 320000.0 0.46 923391.0 369000.0 0.52 0.6865 0.9981 2069995 Maybridge1_001040 COc1cc(OC)cc(/N=C\2/NC(C)(C)C(=C)S2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H07 compound treatment 933108.0 372000.0 0.53 981688.0 428000.0 0.6 0.7959 0.9982 1713948 Maybridge1_001041 Cc1cc(ccc1Cl)C(=O)CN2C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H08 compound treatment 927282.0 366000.0 0.52 977919.0 424000.0 0.59 0.7863 0.998 2069996 Maybridge1_001042 CC(=O)c1cc(Br)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H09 compound treatment 908431.0 347000.0 0.49 963738.0 410000.0 0.57 0.7533 0.9974 2069997 Maybridge1_001043 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc(n[nH]2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H10 compound treatment 931740.0 371000.0 0.53 965028.0 411000.0 0.57 0.778 0.9991 2069998 Maybridge1_001044 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H11 compound treatment 941183.0 380000.0 0.54 1002458.0 448000.0 0.63 0.8245 0.9974 1107935 Maybridge1_001045 CC(=O)Nc1ccc(cc1)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H12 compound treatment 884223.0 323000.0 0.46 897713.0 344000.0 0.48 0.6639 0.9998 1300335 Maybridge1_001046 Cc1cc(Oc2cc(C)c(Cl)c(C)c2)c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H13 compound treatment 927478.0 366000.0 0.52 959028.0 405000.0 0.56 0.7678 0.9992 2069999 Maybridge1_001047 Clc1ccc(SCC(=O)Nc2ccc(Br)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H14 compound treatment 878152.0 317000.0 0.45 956000.0 402000.0 0.56 0.7153 0.9942 1404813 Maybridge1_001048 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H15 compound treatment 956179.0 395000.0 0.56 964537.0 410000.0 0.57 0.8021 1.0 2070000 Maybridge1_001049 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccncc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H16 compound treatment 929657.0 369000.0 0.52 926047.0 372000.0 0.52 0.7375 1.0 1719758 Maybridge1_001050 Clc1cccc(Cl)c1CSc2ncc3ccccn23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H17 compound treatment 980740.0 420000.0 0.6 929657.0 376000.0 0.52 0.7924 0.9979 2070001 Maybridge1_001051 [O-][N+](=O)c1cc(ccc1N2CCN(CC2)C(=O)NC(=O)c3ccccc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H18 compound treatment 919687.0 359000.0 0.51 908978.0 355000.0 0.49 0.7107 0.9999 2070002 Maybridge1_001052 FC(F)(F)C(=O)c1nc(SCc2ccc(Cl)cc2)n3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H19 compound treatment 944914.0 384000.0 0.55 924673.0 371000.0 0.52 0.7515 0.9996 2070003 Maybridge1_001053 FC(F)(F)c1cccc(NC(=S)Nc2ccccn2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H20 compound treatment 909671.0 349000.0 0.5 889812.0 336000.0 0.47 0.6817 0.9996 2070004 Maybridge1_001054 Cc1ccc(NC(=S)NN=C2CCCCCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H21 compound treatment 945163.0 384000.0 0.55 906248.0 352000.0 0.49 0.7336 0.9986 1593023 Maybridge1_001055 CC(=O)Nc1cc(=O)oc2ccc(NC(=O)c3ccc(F)cc3)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H22 compound treatment 903559.0 343000.0 0.49 872746.0 319000.0 0.44 0.6587 0.999 2070005 Maybridge1_001056 Cc1cc(OCOc2ccc(Cl)c(C)c2)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H23 mock treatment 941598.0 381000.0 0.54 869181.0 315000.0 0.44 0.6934 0.9947 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 H24 mock treatment 128851.0 -432000.0 -0.61 141109.0 -413000.0 -0.58 -0.8419 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I01 compound treatment 863428.0 302000.0 0.43 844838.0 291000.0 0.41 0.5908 0.9996 1094153 Maybridge1_001057 NNC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I02 compound treatment 847395.0 286000.0 0.41 865650.0 312000.0 0.43 0.5952 0.9995 2070006 Maybridge1_001058 Cc1onc(c1c2nc3cccc(F)c3c(=O)o2)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I03 compound treatment 905060.0 344000.0 0.49 926367.0 372000.0 0.52 0.7131 0.9996 2070007 Maybridge1_001059 Cc1cc(=O)cc(C)n1NC(=O)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I04 compound treatment 892634.0 332000.0 0.47 926900.0 373000.0 0.52 0.7011 0.9988 1492347 Maybridge1_001060 Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I05 compound treatment 866428.0 305000.0 0.43 971524.0 417000.0 0.58 0.7188 0.9896 2070008 Maybridge1_001061 Clc1ccc(cc1)C(C#N)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I06 compound treatment 875445.0 314000.0 0.45 922842.0 369000.0 0.51 0.6798 0.9976 2070009 Maybridge1_001062 CC(C)(C)SC(=S)SCC(=O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I07 compound treatment 926171.0 365000.0 0.52 1015127.0 461000.0 0.64 0.8219 0.9944 2070010 Maybridge1_001063 Clc1cccc(Cl)c1C(=O)NC(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I08 compound treatment 908430.0 347000.0 0.49 972943.0 419000.0 0.58 0.7624 0.9965 2070011 Maybridge1_001064 CC(C=C)N1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I09 compound treatment 954225.0 393000.0 0.56 967077.0 413000.0 0.58 0.8027 0.9999 2070012 Maybridge1_001065 [O-][N+](=O)c1ccc(cc1)C(=O)NCCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I10 compound treatment 936510.0 375000.0 0.53 996674.0 443000.0 0.62 0.8141 0.9974 1648615 Maybridge1_001066 CC1CN(Cc2cc(C)c(O)c(C)c2)CC(C)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I11 compound treatment 924470.0 363000.0 0.52 1025802.0 472000.0 0.66 0.8307 0.9929 2070013 Maybridge1_001067 Clc1ccc(SCc2ccc(cc2)c3nc4ccccc4[nH]3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I12 compound treatment 932044.0 371000.0 0.53 969302.0 415000.0 0.58 0.7826 0.9989 1024512 Maybridge1_001068 COc1cc2CCN=C(C)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I13 compound treatment 897654.0 337000.0 0.48 1007184.0 453000.0 0.63 0.7853 0.9906 1715965 Maybridge1_001069 Cc1onc(c1C(=O)NCCS(=O)(=O)c2ccc(C)cc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I14 compound treatment 910178.0 349000.0 0.5 931657.0 378000.0 0.53 0.7235 0.9996 2070014 Maybridge1_001070 NCC(=O)c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I15 compound treatment 952125.0 391000.0 0.56 963277.0 409000.0 0.57 0.7968 0.9999 1230300 Maybridge1_001071 Nc1c(Cl)cc(cc1Cl)C(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I16 compound treatment 902268.0 341000.0 0.49 960757.0 407000.0 0.57 0.7442 0.997 2070015 Maybridge1_001072 Clc1ccc(COC(=O)c2cccs2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I17 compound treatment 966845.0 406000.0 0.58 979735.0 426000.0 0.59 0.8279 0.9999 2070016 Maybridge1_001073 Cc1nn(nc1C(=O)NNC(=S)Nc2ccc(C)c(C)c2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I18 compound treatment 905832.0 345000.0 0.49 933513.0 379000.0 0.53 0.7209 0.9993 2070017 Maybridge1_001074 Fc1ccc(NC(=O)CS(=O)(=O)Cc2c(F)cccc2Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I19 compound treatment 923822.0 363000.0 0.52 960564.0 406000.0 0.57 0.7657 0.9989 2070018 Maybridge1_001075 CSC1=NCCCN1C(=O)c2c(C)onc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I20 compound treatment 896355.0 335000.0 0.48 921882.0 368000.0 0.51 0.6999 0.9993 1565983 Maybridge1_001076 COc1ccc(c2c(C)nn(C)c2C)c(c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I21 compound treatment 937675.0 377000.0 0.54 934642.0 381000.0 0.53 0.7541 1.0 1063570 Maybridge1_001077 [O-][N+](=O)c1ccc(Oc2ccc(Cl)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I22 compound treatment 896546.0 336000.0 0.48 880650.0 327000.0 0.46 0.6594 0.9997 2070019 Maybridge1_001078 Nc1ccccc1C(=O)NCCCn2ccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I23 mock treatment 974820.0 414000.0 0.59 899930.0 346000.0 0.48 0.7572 0.9951 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 I24 mock treatment 158732.0 -402000.0 -0.57 148297.0 -406000.0 -0.57 -0.8047 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J01 compound treatment 872526.0 311000.0 0.44 822023.0 268000.0 0.37 0.5775 0.9964 2070020 Maybridge1_001079 CC1CN(CC(C)O1)C2=NCCN2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J02 compound treatment 873544.0 313000.0 0.44 848206.0 294000.0 0.41 0.6043 0.9992 2070021 Maybridge1_001080 Fc1ccc(OC(=O)NC(=O)c2c(Cl)cccc2Cl)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J03 compound treatment 912811.0 352000.0 0.5 865464.0 311000.0 0.43 0.6608 0.9975 2070022 Maybridge1_001081 COc1ccccc1Oc2ccc(cc2NC(=O)NC(=O)c3c(F)cccc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J04 compound treatment 849774.0 289000.0 0.41 840461.0 286000.0 0.4 0.5728 0.9999 1481239 Maybridge1_001082 COc1ccc(cc1OC)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J05 compound treatment 881470.0 320000.0 0.46 918226.0 364000.0 0.51 0.6813 0.9985 2070023 Maybridge1_001083 Cc1cc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])c3c(Cl)ccc(C)c3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J06 compound treatment 883481.0 322000.0 0.46 921488.0 367000.0 0.51 0.6866 0.9985 1920653 Maybridge1_001084 Clc1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J07 compound treatment 972512.0 411000.0 0.59 944914.0 391000.0 0.55 0.7992 0.9994 1043741 Maybridge1_001085 CSc1ccc(Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J08 compound treatment 925416.0 364000.0 0.52 977366.0 423000.0 0.59 0.7839 0.9979 2070024 Maybridge1_001086 CC(=O)c1cc(Cl)cc(Cl)c1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J09 compound treatment 941891.0 381000.0 0.54 999408.0 445000.0 0.62 0.8222 0.9977 2070025 Maybridge1_001087 Clc1c(sc2ccccc12)C(=O)N/N=C/c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J10 compound treatment 872565.0 312000.0 0.44 949494.0 395000.0 0.55 0.7032 0.9941 1296994 Maybridge1_001088 Cc1cc(Oc2ccnc3cc(Cl)ccc23)cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J11 compound treatment 925363.0 364000.0 0.52 983037.0 429000.0 0.6 0.7894 0.9974 2070026 Maybridge1_001089 Cc1cc(ccc1Cl)C(=O)CC(Sc2ccccc2N)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J12 compound treatment 867961.0 307000.0 0.44 925887.0 372000.0 0.52 0.6753 0.9963 1724700 Maybridge1_001090 Cc1cc(Oc2ccc(Cl)c(C)c2)c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J13 compound treatment 933495.0 372000.0 0.53 948488.0 394000.0 0.55 0.7635 0.9998 2070027 Maybridge1_001091 Cc1ccc(SCC(=O)Nc2ccc(Br)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J14 compound treatment 928022.0 367000.0 0.52 942203.0 388000.0 0.54 0.7518 0.9998 2070028 Maybridge1_001092 COC(=O)c1sc2cc(Cl)ccc2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J15 compound treatment 944997.0 384000.0 0.55 962345.0 408000.0 0.57 0.7887 0.9998 2070029 Maybridge1_001093 CC(=N)NS(=O)(=O)c1cc(Cl)c(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J16 compound treatment 917110.0 356000.0 0.51 879503.0 325000.0 0.45 0.679 0.9985 1006327 Maybridge1_001094 CCOC(=O)c1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J17 compound treatment 919742.0 359000.0 0.51 914428.0 360000.0 0.5 0.7161 1.0 2070030 Maybridge1_001095 Cc1ccc(SCC(=O)N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J18 compound treatment 888095.0 327000.0 0.47 888552.0 334000.0 0.47 0.6587 1.0 2070031 Maybridge1_001096 CC(=NNC(=S)Nc1ccc(C)cc1C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J19 compound treatment 918691.0 358000.0 0.51 902969.0 349000.0 0.49 0.7037 0.9998 2070032 Maybridge1_001097 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/C=N/OCc2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J20 compound treatment 889468.0 328000.0 0.47 882292.0 328000.0 0.46 0.6539 0.9999 2070033 Maybridge1_001098 Cc1cc(C)c(NC(=S)NN=C2CCCCCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J21 compound treatment 903864.0 343000.0 0.49 900106.0 346000.0 0.48 0.686 1.0 1504079 Maybridge1_001099 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc3oc(=O)c(NC(=O)C)cc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J22 compound treatment 887465.0 326000.0 0.46 829031.0 275000.0 0.38 0.5994 0.9955 2070034 Maybridge1_001100 CS/C(=N/N=C/c1c(Cl)cccc1Cl)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J23 mock treatment 952830.0 392000.0 0.56 848415.0 294000.0 0.41 0.6843 0.9887 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 J24 mock treatment 131303.0 -430000.0 -0.61 154018.0 -400000.0 -0.56 -0.8267 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K01 compound treatment 845318.0 284000.0 0.4 825523.0 271000.0 0.38 0.5536 0.9995 2070035 Maybridge1_001101 Cc1cc(cc([N+](=O)[O-])c1Sc2ccc(Cl)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K02 compound treatment 817161.0 256000.0 0.36 847850.0 294000.0 0.41 0.5473 0.9983 2070036 Maybridge1_001102 Fc1cccc2nc(oc(=O)c12)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K03 compound treatment 877593.0 317000.0 0.45 883083.0 329000.0 0.46 0.6428 1.0 2070037 Maybridge1_001103 CC(=O)c1cc2cc(ccc2o1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K04 compound treatment 867518.0 306000.0 0.44 855784.0 302000.0 0.42 0.6057 0.9998 1359192 Maybridge1_001104 Cc1cc(Oc2ccc(N)cn2)cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K05 compound treatment 882171.0 321000.0 0.46 941642.0 388000.0 0.54 0.7051 0.9965 1364082 Maybridge1_001105 COc1cc(cc(OC)c1OC)C(C#N)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K06 compound treatment 869399.0 308000.0 0.44 899854.0 346000.0 0.48 0.6511 0.9989 2070038 Maybridge1_001106 CC(C)(C)SC(=S)SCC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K07 compound treatment 871943.0 311000.0 0.44 975361.0 421000.0 0.59 0.7281 0.9902 1127157 Maybridge1_001107 Nc1ccc(Cl)cc1C(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K08 compound treatment 851437.0 290000.0 0.41 882905.0 329000.0 0.46 0.6163 0.9986 2070039 Maybridge1_001108 CN(C)c1cc(N2CCCC2)c(F)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K09 compound treatment 893320.0 332000.0 0.47 960068.0 406000.0 0.57 0.7345 0.996 1208334 Maybridge1_001109 Clc1ccc(cc1Cl)C(=O)NCCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K10 compound treatment 868687.0 308000.0 0.44 930732.0 377000.0 0.53 0.6808 0.9959 1428930 Maybridge1_001110 CC1CC(C)CN(Cc2cc(C)c(O)c(C)c2)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K11 compound treatment 900198.0 339000.0 0.48 959773.0 406000.0 0.57 0.7412 0.9968 2070040 Maybridge1_001111 COc1ccc(C(C(=O)C)C(=O)C)c(c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K12 compound treatment 868242.0 307000.0 0.44 941322.0 387000.0 0.54 0.6908 0.9945 2070041 Maybridge1_001112 Nc1cccc(NC=C(C#N)C#N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K13 compound treatment 891991.0 331000.0 0.47 949812.0 396000.0 0.55 0.7231 0.9969 1667067 Maybridge1_001113 Cc1onc(c1C(=O)NCC(=O)NN)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K14 compound treatment 865115.0 304000.0 0.43 935929.0 382000.0 0.53 0.6824 0.9947 1019894 Maybridge1_001114 NCC(=O)c1ccc(Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K15 compound treatment 943510.0 382000.0 0.54 972855.0 419000.0 0.58 0.7976 0.9994 2070042 Maybridge1_001115 Cc1nn(nc1C(=O)Nc2nnc(s2)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K16 compound treatment 892510.0 331000.0 0.47 911338.0 357000.0 0.5 0.6857 0.9996 2070043 Maybridge1_001116 Fc1ccc(NC(=O)CSCc2ccc(Cl)c(Cl)c2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K17 compound treatment 896687.0 336000.0 0.48 931488.0 377000.0 0.53 0.7097 0.9988 2070044 Maybridge1_001117 Cc1nn(nc1C(=O)NNC(=S)Nc2ccc(Cl)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K18 compound treatment 870575.0 310000.0 0.44 897871.0 344000.0 0.48 0.6503 0.9991 2070045 Maybridge1_001118 N/C(=N\OC(=O)c1cccs1)/c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K19 compound treatment 907364.0 346000.0 0.49 915823.0 362000.0 0.5 0.705 0.9999 1104645 Maybridge1_001119 Nc1ccccc1C(=O)NCCc2c[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K20 compound treatment 882034.0 321000.0 0.46 865937.0 312000.0 0.43 0.6303 0.9997 1573183 Maybridge1_001120 Cc1onc(c1C(=O)Oc2ccc(F)cc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K21 compound treatment 912750.0 352000.0 0.5 919724.0 366000.0 0.51 0.7143 1.0 2070046 Maybridge1_001121 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K22 compound treatment 877146.0 316000.0 0.45 858241.0 304000.0 0.42 0.6178 0.9996 1010836 Maybridge1_001122 CCOC(=O)c1cnc(S)nc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K23 mock treatment 926669.0 366000.0 0.52 892642.0 339000.0 0.47 0.7016 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 K24 mock treatment 159696.0 -401000.0 -0.57 156040.0 -398000.0 -0.56 -0.7961 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L01 compound treatment 854451.0 293000.0 0.42 785115.0 231000.0 0.32 0.5229 0.9918 1703714 Maybridge1_001123 Cc1cccc(c1)c2nc3cccc(F)c3c(=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L02 compound treatment 840344.0 279000.0 0.4 779437.0 225000.0 0.31 0.5031 0.9933 2070047 Maybridge1_001124 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)Nc2ccc(F)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L03 compound treatment 886032.0 325000.0 0.46 843413.0 289000.0 0.4 0.6121 0.9977 2070048 Maybridge1_001125 [O-][N+](=O)c1cccnc1Sc2ncc3ccccn23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L04 compound treatment 859149.0 298000.0 0.42 824494.0 270000.0 0.38 0.5665 0.9983 1355972 Maybridge1_001126 Clc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L05 compound treatment 894007.0 333000.0 0.47 865603.0 312000.0 0.43 0.6421 0.9991 2070049 Maybridge1_001127 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3cc(F)ccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L06 compound treatment 854216.0 293000.0 0.42 839549.0 285000.0 0.4 0.5763 0.9997 1558904 Maybridge1_001128 Nc1ccccc1C(=O)NCCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L07 compound treatment 905678.0 345000.0 0.49 892419.0 338000.0 0.47 0.6802 0.9998 1540934 Maybridge1_001129 COc1ccc2N(CCCc2c1)C(=O)NC(=O)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L08 compound treatment 892733.0 332000.0 0.47 892964.0 339000.0 0.47 0.6678 1.0 2070050 Maybridge1_001130 CC(=O)c1cc(F)ccc1OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L09 compound treatment 893807.0 333000.0 0.47 917842.0 364000.0 0.51 0.6934 0.9994 2070051 Maybridge1_001131 CCOC(=O)CNC(=O)c1c(F)cccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L10 compound treatment 912509.0 351000.0 0.5 887694.0 334000.0 0.47 0.6824 0.9994 2070052 Maybridge1_001132 COc1ccc(cc1CSc2nc3cc(ccc3[nH]2)C(F)(F)F)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L11 compound treatment 910469.0 349000.0 0.5 935485.0 381000.0 0.53 0.7275 0.9994 2070053 Maybridge1_001133 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC(C2)c4c(F)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L12 compound treatment 855495.0 294000.0 0.42 862080.0 308000.0 0.43 0.5999 0.9999 1583726 Maybridge1_001134 Cc1cc(Oc2ccc(Cl)cc2)c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L13 compound treatment 914488.0 353000.0 0.5 918585.0 365000.0 0.51 0.7149 1.0 2070054 Maybridge1_001135 Brc1ccc(NC(=O)CSc2ncccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L14 compound treatment 866326.0 305000.0 0.43 852061.0 298000.0 0.42 0.6009 0.9998 2070055 Maybridge1_001136 COc1ccc(Cc2nc(cs2)C(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L15 compound treatment 928843.0 368000.0 0.52 898883.0 345000.0 0.48 0.7099 0.9991 2070056 Maybridge1_001137 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L16 compound treatment 902301.0 341000.0 0.49 858502.0 304000.0 0.42 0.6434 0.9978 2070057 Maybridge1_001138 Clc1cc(COc2ccc(cc2)S(=O)(=O)c3ccc(OCc4cc(Cl)cc5COCOc45)cc3)c6OCOCc6c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L17 compound treatment 948004.0 387000.0 0.55 838906.0 285000.0 0.4 0.67 0.9872 2070058 Maybridge1_001139 CC(=O)N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L18 compound treatment 897254.0 336000.0 0.48 847291.0 293000.0 0.41 0.6273 0.997 2070059 Maybridge1_001140 Fc1ccc(NC(=O)CC#N)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L19 compound treatment 914731.0 354000.0 0.5 853756.0 300000.0 0.42 0.6512 0.9958 2070060 Maybridge1_001141 Nc1nc2c(F)cc(F)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L20 compound treatment 908524.0 347000.0 0.49 847253.0 293000.0 0.41 0.6386 0.9956 2070061 Maybridge1_001142 C/C(=N\NC(=S)N)/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L21 compound treatment 915875.0 355000.0 0.5 858218.0 304000.0 0.42 0.6568 0.9963 2070062 Maybridge1_001143 Cc1ccc2nc(N)sc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L22 compound treatment 898616.0 338000.0 0.48 848266.0 294000.0 0.41 0.6296 0.9969 1919994 Maybridge1_001144 CN(C)c1ccc(/C=N/NC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L23 mock treatment 929621.0 369000.0 0.52 852858.0 299000.0 0.42 0.6653 0.9935 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 L24 mock treatment 165092.0 -396000.0 -0.56 127709.0 -426000.0 -0.59 -0.8186 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M01 compound treatment 841269.0 280000.0 0.4 800696.0 247000.0 0.34 0.525 0.9973 1469999 Maybridge1_001145 NC(=O)c1cccnc1Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M02 compound treatment 853673.0 293000.0 0.42 805417.0 251000.0 0.35 0.5421 0.9964 1365534 Maybridge1_001146 CC(C)(C)C(=O)Nc1cccc(F)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M03 compound treatment 844519.0 283000.0 0.4 880104.0 326000.0 0.45 0.6066 0.9982 1075845 Maybridge1_001147 OC(=O)c1ccccc1C(=O)Nc2cc(ccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M04 compound treatment 846615.0 286000.0 0.41 779331.0 225000.0 0.31 0.5093 0.9919 1223037 Maybridge1_001148 CC(C)(C)c1ccc(Oc2ccc(N)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M05 compound treatment 876271.0 315000.0 0.45 879351.0 325000.0 0.45 0.6378 1.0 1020373 Maybridge1_001149 Nc1ccc(Br)cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M06 compound treatment 865425.0 304000.0 0.43 837618.0 284000.0 0.4 0.5857 0.999 2070063 Maybridge1_001150 CC(C)(C)SC(=S)SCC(=O)c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M07 compound treatment 895523.0 334000.0 0.48 913752.0 360000.0 0.5 0.6911 0.9996 1571162 Maybridge1_001151 CNc1ccccc1C(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M08 compound treatment 838841.0 278000.0 0.4 837961.0 284000.0 0.4 0.5593 1.0 2070064 Maybridge1_001152 CC1CCCN(C1)c2cc(N(C)C)c(cc2F)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M09 compound treatment 912785.0 352000.0 0.5 932216.0 378000.0 0.53 0.7266 0.9997 1632631 Maybridge1_001153 O=C(NCCc1ccncc1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M10 compound treatment 868251.0 307000.0 0.44 909038.0 355000.0 0.5 0.659 0.9981 1432647 Maybridge1_001154 COc1cc2CCN(Cc3cc(C)c(O)c(C)c3)C(C)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M11 compound treatment 886536.0 326000.0 0.46 927541.0 373000.0 0.52 0.6956 0.9983 2070065 Maybridge1_001155 Clc1ccc(SCC(=O)NCc2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M12 compound treatment 862210.0 301000.0 0.43 909767.0 356000.0 0.5 0.6536 0.9973 2070066 Maybridge1_001156 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCCCC3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M13 compound treatment 906511.0 345000.0 0.49 913328.0 359000.0 0.5 0.7017 1.0 2070067 Maybridge1_001157 COc1cc(cc(OC)c1OC)C2=NNC(=O)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M14 compound treatment 910504.0 349000.0 0.5 885831.0 332000.0 0.46 0.6786 0.9994 2070068 Maybridge1_001158 Fc1ccc(OC(=O)c2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M15 compound treatment 933569.0 373000.0 0.53 879848.0 326000.0 0.45 0.6959 0.9971 1504770 Maybridge1_001159 Cc1nn(nc1C(=O)Nc2ccc3[nH]ncc3c2)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M16 compound treatment 882026.0 321000.0 0.46 858943.0 305000.0 0.43 0.6234 0.9994 2070069 Maybridge1_001160 Fc1ccc(NC(=O)CSCc2c(Cl)cccc2Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M17 compound treatment 926180.0 365000.0 0.52 883478.0 329000.0 0.46 0.692 0.9981 1236643 Maybridge1_001161 Fc1cccc(F)c1C(=O)NC(=O)N2CCSC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M18 compound treatment 880618.0 320000.0 0.45 852242.0 298000.0 0.42 0.6154 0.999 1108196 Maybridge1_001162 [O-][N+](=O)c1ccc(cc1)c2noc(n2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M19 compound treatment 940068.0 379000.0 0.54 880538.0 326000.0 0.46 0.7031 0.9965 1093772 Maybridge1_001163 O=C(Nc1nncs1)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M20 compound treatment 880739.0 320000.0 0.45 845459.0 291000.0 0.41 0.6088 0.9984 1737692 Maybridge1_001164 CC(=O)Nc1cccc(F)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M21 compound treatment 914912.0 354000.0 0.5 836501.0 282000.0 0.39 0.6344 0.9927 2070070 Maybridge1_001165 Cc1cc(Oc2ccc(cn2)[N+](=O)[O-])cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M22 compound treatment 864225.0 303000.0 0.43 850305.0 296000.0 0.41 0.597 0.9998 2070071 Maybridge1_001166 CC(C)(C)c1cc([N+](=O)[O-])c(OC(=O)c2ccc(Cl)cc2Cl)c(c1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M23 mock treatment 935966.0 375000.0 0.53 857907.0 304000.0 0.42 0.6767 0.9935 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 M24 mock treatment 332878.0 -228000.0 -0.32 641530.0 87500.0 0.12 -0.1432 -0.4131 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N01 compound treatment 872723.0 312000.0 0.44 769382.0 215000.0 0.3 0.5258 0.982 1602236 Maybridge1_001167 S=C(NCc1ccccn1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N02 compound treatment 867719.0 307000.0 0.44 778300.0 224000.0 0.31 0.5295 0.9867 1628081 Maybridge1_001168 Cc1onc(c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N03 compound treatment 844816.0 284000.0 0.4 810677.0 257000.0 0.36 0.5384 0.9982 2070072 Maybridge1_001169 [O-][N+](=O)c1ccc(Sc2ncc3ccccn23)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N04 compound treatment 864472.0 303000.0 0.43 813136.0 259000.0 0.36 0.5606 0.9961 1468368 Maybridge1_001170 Clc1ccc(Oc2ccccc2NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N05 compound treatment 917101.0 356000.0 0.51 836893.0 283000.0 0.39 0.637 0.9924 2070073 Maybridge1_001171 Cc1cc(Oc2ncccc2[N+](=O)[O-])c3cc(Cl)ccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N06 compound treatment 869399.0 308000.0 0.44 784337.0 230000.0 0.32 0.5372 0.9883 1602444 Maybridge1_001172 Cc1c(Cl)cccc1Nc2nc(cs2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N07 compound treatment 926197.0 365000.0 0.52 879151.0 325000.0 0.45 0.6878 0.9977 2070074 Maybridge1_001173 Clc1ccc(cc1)C2=NNC(=O)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N08 compound treatment 906980.0 346000.0 0.49 862102.0 308000.0 0.43 0.6516 0.9977 2070075 Maybridge1_001174 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2cc(F)ccc2OC(=O)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N09 compound treatment 905644.0 345000.0 0.49 891768.0 338000.0 0.47 0.6796 0.9998 2070076 Maybridge1_001175 C/C(=N\Nc1ccccc1)/C=N/O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N10 compound treatment 866209.0 305000.0 0.43 869696.0 316000.0 0.44 0.6181 1.0 1595657 Maybridge1_001176 Cc1ccc(cc1C)n2c(csc2=Nc3ccccn3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N11 compound treatment 913760.0 353000.0 0.5 874858.0 321000.0 0.45 0.671 0.9984 2070077 Maybridge1_001177 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC(C2)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N12 compound treatment 859746.0 299000.0 0.42 850740.0 297000.0 0.41 0.5929 0.9999 1257335 Maybridge1_001178 Fc1ccc(Oc2ccnc3cc(Cl)ccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N13 compound treatment 903569.0 343000.0 0.49 871793.0 318000.0 0.44 0.6578 0.9989 2070078 Maybridge1_001179 Fc1cc(Br)c(c(Br)c1Cl)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N14 compound treatment 901568.0 341000.0 0.48 833296.0 279000.0 0.39 0.6178 0.9942 2070079 Maybridge1_001180 Cc1ccc(Cc2nc(cs2)C(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N15 compound treatment 926064.0 365000.0 0.52 854050.0 300000.0 0.42 0.6629 0.9943 2070080 Maybridge1_001181 CS(=O)(=O)NNc1c(Cl)cc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N16 compound treatment 900870.0 340000.0 0.48 817977.0 264000.0 0.37 0.602 0.991 1633692 Maybridge1_001182 Cc1onc(c1C(=O)Nc2nnc(s2)C3CC3)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N17 compound treatment 956577.0 396000.0 0.56 853523.0 299000.0 0.42 0.6931 0.9893 1014750 Maybridge1_001183 COc1ccc(NC(=O)CC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N18 compound treatment 901122.0 340000.0 0.48 814775.0 261000.0 0.36 0.5991 0.9901 2070081 Maybridge1_001184 Fc1ccc(OCOc2ccc(F)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N19 compound treatment 956985.0 396000.0 0.56 846898.0 293000.0 0.41 0.6869 0.9876 2070082 Maybridge1_001185 Oc1ccnc(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N20 compound treatment 920116.0 359000.0 0.51 807343.0 253000.0 0.35 0.6109 0.9838 2070083 Maybridge1_001186 CS/C(=N/N=C(\C)/c1ccc(Cl)c(Cl)c1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N21 compound treatment 943114.0 382000.0 0.54 831029.0 277000.0 0.39 0.6573 0.986 2070084 Maybridge1_001187 Nc1nc2ccc(Cl)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N22 compound treatment 918532.0 357000.0 0.51 810290.0 256000.0 0.36 0.6122 0.9851 2070085 Maybridge1_001188 NC(=S)N/N=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N23 mock treatment 965289.0 404000.0 0.57 827483.0 273000.0 0.38 0.6761 0.9801 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 N24 mock treatment 352366.0 -209000.0 -0.3 634057.0 80000.0 0.11 -0.131 -0.4131 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O01 compound treatment 823462.0 262000.0 0.37 779569.0 225000.0 0.31 0.4863 0.9964 1177922 Maybridge1_001189 O=c1c2ccccc2oc3ncccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O02 compound treatment 816574.0 256000.0 0.36 734697.0 181000.0 0.25 0.4351 0.984 1120165 Maybridge1_001190 Fc1cccc(NC(=O)C(C2CCCC2)c3ccccc3)c1C(=O)NCc4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O03 compound treatment 851032.0 290000.0 0.41 773505.0 219000.0 0.31 0.508 0.9892 2070086 Maybridge1_001191 COC(=O)c1c(OC)ccc([N+](=O)[O-])c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O04 compound treatment 819839.0 259000.0 0.37 789403.0 235000.0 0.33 0.4923 0.9984 2070087 Maybridge1_001192 Cc1cc(Oc2ccc(cn2)[N+](=O)[O-])ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O05 compound treatment 858051.0 297000.0 0.42 819457.0 265000.0 0.37 0.5604 0.9978 1033922 Maybridge1_001193 Nc1ncc(Br)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O06 compound treatment 844261.0 283000.0 0.4 810494.0 256000.0 0.36 0.5377 0.9982 1034245 Maybridge1_001194 [O-][N+](=O)c1ccc(Oc2c(Cl)cccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O07 compound treatment 879760.0 319000.0 0.45 866069.0 312000.0 0.44 0.6282 0.9998 1249559 Maybridge1_001195 OC(=O)c1ccccc1NCC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O08 compound treatment 854171.0 293000.0 0.42 840052.0 286000.0 0.4 0.5768 0.9998 1221542 Maybridge1_001196 Clc1ccc(NC(=O)NC(=O)c2ccccc2N3CCCCC3)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O09 compound treatment 874446.0 313000.0 0.45 887873.0 334000.0 0.47 0.6443 0.9998 1284064 Maybridge1_001197 CC(C)NC(=S)NCCc1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O10 compound treatment 854868.0 294000.0 0.42 835293.0 281000.0 0.39 0.5728 0.9995 2070088 Maybridge1_001198 [O-][N+](=O)c1cccnc1Sc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O11 compound treatment 868484.0 307000.0 0.44 859930.0 306000.0 0.43 0.6108 0.9999 2070089 Maybridge1_001199 SC1=NCN(CCc2ccncc2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O12 compound treatment 821198.0 260000.0 0.37 813190.0 259000.0 0.36 0.5171 0.9999 2070090 Maybridge1_001200 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)N3CCOCC3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O13 compound treatment 852098.0 291000.0 0.41 848586.0 295000.0 0.41 0.5831 1.0 2070091 Maybridge1_001201 CC(=O)C(=NNc1ccc(F)cc1F)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O14 compound treatment 864131.0 303000.0 0.43 805074.0 251000.0 0.35 0.5523 0.9947 2070092 Maybridge1_001202 Fc1ccc(OC(=O)c2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O15 compound treatment 857387.0 296000.0 0.42 850650.0 297000.0 0.41 0.5905 1.0 2070093 Maybridge1_001203 Cc1nn(nc1C(=O)NN)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O16 compound treatment 858263.0 297000.0 0.42 804578.0 251000.0 0.35 0.5459 0.9955 2070094 Maybridge1_001204 Fc1ccc(NC(=O)CSCc2c(F)cccc2Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O17 compound treatment 922922.0 362000.0 0.51 822766.0 269000.0 0.37 0.6289 0.9879 1542709 Maybridge1_001205 Cc1ccc(SCc2ccc(cc2)C(=O)Nc3ccc(C)cc3O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O18 compound treatment 852776.0 292000.0 0.41 789255.0 235000.0 0.33 0.5253 0.9932 2070095 Maybridge1_001206 CC1CN(CC(C)O1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O19 compound treatment 897846.0 337000.0 0.48 830557.0 276000.0 0.39 0.6114 0.9942 1582082 Maybridge1_001207 CCc1nnc(NC(=O)c2ccncc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O20 compound treatment 893577.0 333000.0 0.47 815209.0 261000.0 0.36 0.5919 0.9917 1207012 Maybridge1_001208 S=C1NCN(CN1)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O21 compound treatment 903307.0 342000.0 0.49 842824.0 289000.0 0.4 0.6289 0.9956 2070096 Maybridge1_001209 Fc1cc2nn[nH]c2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O22 compound treatment 877449.0 316000.0 0.45 779186.0 225000.0 0.31 0.5402 0.9845 2070097 Maybridge1_001210 CCOC(=O)c1cnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)nc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O23 mock treatment 915719.0 355000.0 0.5 828378.0 274000.0 0.38 0.6272 0.9907 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 O24 mock treatment 435881.0 -125000.0 -0.18 561930.0 7850.0 0.01 -0.1181 -0.6623 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P01 compound treatment 855700.0 295000.0 0.42 755123.0 201000.0 0.28 0.4946 0.9809 1307492 Maybridge1_001211 Clc1ccc(cc1)S(=O)(=O)NC2CCS(=O)(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P02 compound treatment 877537.0 317000.0 0.45 758373.0 204000.0 0.28 0.5197 0.9757 1494020 Maybridge1_001212 Cc1onc(c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P03 compound treatment 873094.0 312000.0 0.44 761182.0 207000.0 0.29 0.518 0.9784 2070098 Maybridge1_001213 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3c(Cl)ccc(C)c3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P04 compound treatment 890248.0 329000.0 0.47 751836.0 198000.0 0.28 0.5261 0.9682 2070099 Maybridge1_001214 Clc1ccc(Oc2ccccc2NC(=O)C(Cl)(Cl)Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P05 compound treatment 868382.0 307000.0 0.44 771170.0 217000.0 0.3 0.5232 0.9839 2070100 Maybridge1_001215 Cc1cc(Oc2ncccc2[N+](=O)[O-])c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P06 compound treatment 867649.0 307000.0 0.44 751877.0 198000.0 0.28 0.5034 0.9756 1419346 Maybridge1_001216 Cc1ccc(Nc2nc(cs2)C(C)(C)C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P07 compound treatment 913009.0 352000.0 0.5 803788.0 250000.0 0.35 0.6002 0.9843 1133002 Maybridge1_001217 COc1cc(cc(OC)c1OC)C(=O)c2ccccc2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P08 compound treatment 885455.0 324000.0 0.46 805141.0 251000.0 0.35 0.5738 0.9907 2070101 Maybridge1_001218 CCOc1c(Br)cc(Br)cc1/C=C\2/SC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P09 compound treatment 896654.0 336000.0 0.48 820298.0 266000.0 0.37 0.6 0.9923 1920882 Maybridge1_001219 Clc1cccc(Cl)c1/C=N/NC(=O)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P10 compound treatment 891752.0 331000.0 0.47 824684.0 271000.0 0.38 0.5994 0.9941 2070102 Maybridge1_001220 OC1(CSc2nc3cc(ccc3n21)C(F)(F)F)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P11 compound treatment 891184.0 330000.0 0.47 826152.0 272000.0 0.38 0.6003 0.9944 2070103 Maybridge1_001221 CCCc1cc(Br)c(c(Br)c1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P12 compound treatment 902124.0 341000.0 0.49 793484.0 239000.0 0.33 0.5791 0.9834 1410530 Maybridge1_001222 Clc1ccc(Oc2ccnc3cc(Cl)ccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P13 compound treatment 903728.0 343000.0 0.49 798596.0 245000.0 0.34 0.5857 0.9848 2070104 Maybridge1_001223 [O-][N+](=O)c1ccc(Oc2c(Cl)cc(cc2Cl)S(=O)(=O)NC(=N)c3ccc(Cl)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P14 compound treatment 905933.0 345000.0 0.49 804926.0 251000.0 0.35 0.5942 0.9863 2070105 Maybridge1_001224 CC(C)(C)c1csc(Cc2ccc(cc2)[N+](=O)[O-])n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P15 compound treatment 914254.0 353000.0 0.5 802605.0 249000.0 0.35 0.6003 0.9836 2070106 Maybridge1_001225 Clc1cc(Cl)c(NNS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P16 compound treatment 1203897.0 643000.0 0.91 1072255.0 518000.0 0.72 1.1575 0.9932 2070107 Maybridge1_001226 COC(=O)/C=C/1\SC(=NC1=O)Cc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P17 compound treatment 928549.0 368000.0 0.52 796948.0 243000.0 0.34 0.6091 0.978 1036063 Maybridge1_001227 Clc1ccc(NC(=S)Nc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P18 compound treatment 937810.0 377000.0 0.54 809808.0 256000.0 0.36 0.6311 0.9804 2070108 Maybridge1_001228 Fc1cccc(NC(=S)NN=C2CCCCCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P19 compound treatment 956066.0 395000.0 0.56 795366.0 241000.0 0.34 0.6352 0.97 2070109 Maybridge1_001229 CC(=O)Nc1cc2cc(NC(=O)c3ccc(cc3)[N+](=O)[O-])ccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P20 compound treatment 914695.0 354000.0 0.5 803440.0 249000.0 0.35 0.6016 0.9838 2070110 Maybridge1_001230 C/C(=N\Nc1nc(cs1)C(C)(C)C)/c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P21 compound treatment 936537.0 376000.0 0.53 800921.0 247000.0 0.34 0.621 0.9775 1723356 Maybridge1_001231 Clc1ccc2sc(NC(=O)NC(=O)c3c(Cl)cccc3Cl)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P22 compound treatment 938941.0 378000.0 0.54 800583.0 247000.0 0.34 0.6231 0.9767 2070111 Maybridge1_001232 CC(C)(C)c1csc(N/N=C/c2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P23 mock treatment 924955.0 364000.0 0.52 798814.0 245000.0 0.34 0.6073 0.9796 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.544 P24 mock treatment 297957.0 -263000.0 -0.37 598802.0 44700.0 0.06 -0.2204 -0.5812 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A01 compound treatment 847767.0 269000.0 0.38 847908.0 239000.0 0.33 0.5063 0.9977 2070112 Maybridge1_001233 CS/C(=N\N=C(/C)\c1ccc(Br)cc1)/N=C/N(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A02 compound treatment 831466.0 252000.0 0.36 859685.0 251000.0 0.35 0.5015 0.9999 2070113 Maybridge1_001234 CC(C)c1ccc(cc1)S(=O)(=O)NC(=N)CSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A03 compound treatment 868304.0 289000.0 0.41 844188.0 236000.0 0.33 0.5233 0.9938 2070114 Maybridge1_001235 Cc1onc(c1C(=O)Oc2ccc(cc2)c3ccc(OC(=O)c4c(C)onc4c5c(Cl)cccc5Cl)cc3)c6c(Cl)cccc6Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A04 compound treatment 854519.0 275000.0 0.39 874075.0 266000.0 0.37 0.5389 0.9996 2070115 Maybridge1_001236 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1OC(=O)c2c(F)cccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A05 compound treatment 918288.0 339000.0 0.48 850305.0 242000.0 0.34 0.5796 0.9847 2070116 Maybridge1_001237 Fc1ccc(NC(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A06 compound treatment 903332.0 324000.0 0.46 909868.0 301000.0 0.42 0.6233 0.9989 2070117 Maybridge1_001238 OCCCc1nc2cc(ccc2[nH]1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A07 compound treatment 895922.0 317000.0 0.45 909783.0 301000.0 0.42 0.6157 0.9994 1705513 Maybridge1_001239 COC(=O)c1sc2ccccc2c1OC(=O)c3cccnc3Oc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A08 compound treatment 919705.0 341000.0 0.48 919924.0 311000.0 0.43 0.6497 0.9985 2070118 Maybridge1_001240 CCOC(=O)c1cc(CC)sc1NC(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A09 compound treatment 906248.0 327000.0 0.47 905271.0 297000.0 0.41 0.6217 0.9983 2070119 Maybridge1_001241 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A10 compound treatment 882115.0 303000.0 0.43 911690.0 303000.0 0.42 0.6037 1.0 1020861 Maybridge1_001242 [O-][N+](=O)c1ccc(cc1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A11 compound treatment 896005.0 317000.0 0.45 892774.0 284000.0 0.4 0.5991 0.998 1214080 Maybridge1_001243 Clc1ccc(cc1Cl)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A12 compound treatment 912853.0 334000.0 0.47 916379.0 308000.0 0.43 0.6393 0.9988 2070120 Maybridge1_001244 Cc1cc(OC(=O)c2c(C)onc2c3ccccc3)n(n1)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A13 compound treatment 921469.0 342000.0 0.49 933197.0 325000.0 0.45 0.6645 0.9993 2070121 Maybridge1_001245 [O-][N+](=O)c1cc(ccc1OC(=O)c2c(F)cccc2F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A14 compound treatment 916815.0 338000.0 0.48 915649.0 307000.0 0.43 0.6425 0.9984 2070122 Maybridge1_001246 Nc1cc(ccc1N2CCCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A15 compound treatment 923849.0 345000.0 0.49 933053.0 325000.0 0.45 0.6668 0.9992 2070123 Maybridge1_001247 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(Cl)c(Cl)c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A16 compound treatment 941670.0 363000.0 0.52 940067.0 332000.0 0.46 0.6916 0.9985 2070124 Maybridge1_001248 Cc1cc(OC(=O)c2cccc(F)c2)n(n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A17 compound treatment 941798.0 363000.0 0.52 914626.0 306000.0 0.43 0.6667 0.9956 2070125 Maybridge1_001249 Fc1ccc(cc1)c2cnc3c(Cl)cc(cc3n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A18 compound treatment 930472.0 351000.0 0.5 891440.0 283000.0 0.39 0.6324 0.9932 2070126 Maybridge1_001250 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A19 compound treatment 886773.0 308000.0 0.44 892528.0 284000.0 0.4 0.5895 0.9988 2070127 Maybridge1_001251 CC(C)(COC(=O)c1ccc(o1)[N+](=O)[O-])Nc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A20 compound treatment 898849.0 320000.0 0.45 871903.0 263000.0 0.37 0.5813 0.9944 2070128 Maybridge1_001252 Oc1cc(ccc1[N+](=O)[O-])N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A21 compound treatment 945497.0 366000.0 0.52 872360.0 264000.0 0.37 0.6287 0.9855 2070129 Maybridge1_001253 O=C/1NC(=S)S\C1=C/c2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A22 compound treatment 887490.0 308000.0 0.44 881527.0 273000.0 0.38 0.5794 0.9975 2070130 Maybridge1_001254 CCC(CC)(NC(=O)NC(=O)c1ccc(F)c(Cl)c1)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A23 mock treatment 881398.0 302000.0 0.43 849908.0 241000.0 0.34 0.5421 0.9927 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 A24 mock treatment 138260.0 -441000.0 -0.63 142367.0 -466000.0 -0.65 -0.903 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B01 compound treatment 842596.0 264000.0 0.37 838906.0 230000.0 0.32 0.4922 0.9971 1223843 Maybridge1_001255 COC(=O)c1sccc1OC(=O)c2c(F)cccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B02 compound treatment 847305.0 268000.0 0.38 903934.0 295000.0 0.41 0.5611 0.9993 1150918 Maybridge1_001256 CCCc1cc(=O)oc2n(nc(C)c12)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B03 compound treatment 861956.0 283000.0 0.4 928031.0 320000.0 0.45 0.5996 0.9987 2070131 Maybridge1_001257 [O-][N+](=O)c1cc(ccc1NCCCn2ccnc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B04 compound treatment 844314.0 265000.0 0.38 894437.0 286000.0 0.4 0.5487 0.9996 2070132 Maybridge1_001258 Oc1cc(ccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B05 compound treatment 906724.0 328000.0 0.47 940203.0 332000.0 0.46 0.6566 1.0 2070133 Maybridge1_001259 CN(C)/C=N/c1nnc(Sc2nc3cc(Cl)ccc3s2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B06 compound treatment 849245.0 270000.0 0.38 953884.0 345000.0 0.48 0.6123 0.9937 2070134 Maybridge1_001260 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B07 compound treatment 916405.0 337000.0 0.48 988896.0 380000.0 0.53 0.7144 0.9987 1257406 Maybridge1_001261 Clc1ccc2sc3nc4ccccc4c(=O)n3c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B08 compound treatment 893346.0 314000.0 0.45 967581.0 359000.0 0.5 0.6702 0.9984 2070135 Maybridge1_001262 O=C1NCCCCC1N2CNC(=S)NC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B09 compound treatment 895532.0 316000.0 0.45 977098.0 369000.0 0.51 0.6817 0.9978 2070136 Maybridge1_001263 CN1N=C(C)/C(=C\c2c(C)nn(C)c2O)/C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B10 compound treatment 911199.0 332000.0 0.47 990937.0 382000.0 0.53 0.7111 0.9982 2070137 Maybridge1_001264 Clc1ccc(cc1Cl)C(=O)NNC(=O)c2cnn(n2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B11 compound treatment 893353.0 314000.0 0.45 992097.0 384000.0 0.54 0.6943 0.996 2070138 Maybridge1_001265 Cc1nn(C)c2oc(=O)c(Cl)c(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B12 compound treatment 863382.0 284000.0 0.4 957611.0 349000.0 0.49 0.6302 0.9957 2070139 Maybridge1_001266 Cc1ccc(cc1)S(=O)(=O)Oc2cc(ccc2[N+](=O)[O-])S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B13 compound treatment 922190.0 343000.0 0.49 960899.0 352000.0 0.49 0.6926 1.0 2070140 Maybridge1_001267 Clc1ccc(cc1)c2nnnn2c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B14 compound treatment 888266.0 309000.0 0.44 903146.0 295000.0 0.41 0.6015 0.9994 1063878 Maybridge1_001268 Cc1ccc(C)c(c1)C(O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B15 compound treatment 971729.0 393000.0 0.56 981958.0 373000.0 0.52 0.7632 0.9994 2070141 Maybridge1_001269 Cc1cc(SCC#N)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B16 compound treatment 907551.0 328000.0 0.47 942773.0 334000.0 0.47 0.66 1.0 2070142 Maybridge1_001270 CC(C)(C)c1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)ccc1Oc3ccc(cc3[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B17 compound treatment 925106.0 346000.0 0.49 1005089.0 397000.0 0.55 0.7391 0.9983 1085663 Maybridge1_001271 Cc1cc(ccc1S(=O)(=O)N)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B18 compound treatment 899754.0 321000.0 0.46 937683.0 329000.0 0.46 0.6471 1.0 2070143 Maybridge1_001272 Cc1cc(c(C)cc1Cl)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B19 compound treatment 892403.0 313000.0 0.45 981259.0 373000.0 0.52 0.6827 0.997 2070144 Maybridge1_001273 CCCCCSc1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B20 compound treatment 874501.0 295000.0 0.42 923982.0 316000.0 0.44 0.6082 0.9997 1382605 Maybridge1_001274 COC(=O)c1ccccc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B21 compound treatment 894685.0 316000.0 0.45 974005.0 366000.0 0.51 0.6778 0.998 1166413 Maybridge1_001275 CCCSc1ncccc1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B22 compound treatment 873931.0 295000.0 0.42 933037.0 325000.0 0.45 0.6166 0.9993 1543350 Maybridge1_001276 COc1cccc(c1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B23 mock treatment 908336.0 329000.0 0.47 921222.0 313000.0 0.44 0.6395 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 B24 mock treatment 129249.0 -450000.0 -0.64 80833.0 -528000.0 -0.74 -0.9727 -0.9976 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C01 compound treatment 794469.0 215000.0 0.31 815973.0 207000.0 0.29 0.4212 0.9996 2070145 Maybridge1_001277 CSC1=NC=C(C#N)C2=NC(C)(NN21)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C02 compound treatment 788642.0 210000.0 0.3 851565.0 243000.0 0.34 0.4505 0.9979 2070146 Maybridge1_001278 Brc1csc(/C=C/2\N=C(OC2=O)c3ccccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C03 compound treatment 842707.0 264000.0 0.37 911337.0 303000.0 0.42 0.5638 0.9982 2070147 Maybridge1_001279 CS/C(=N/N=C/c1ccc2OCOc2c1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C04 compound treatment 832378.0 253000.0 0.36 905330.0 297000.0 0.41 0.5475 0.9976 2070148 Maybridge1_001280 COC(OC)/C(=N/NC(=S)N)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C05 compound treatment 863384.0 284000.0 0.4 903762.0 295000.0 0.41 0.5771 1.0 2070149 Maybridge1_001281 CCCc1nc2cc(Cl)c(Cl)cc2nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C06 compound treatment 800104.0 221000.0 0.31 925549.0 317000.0 0.44 0.5349 0.986 2070150 Maybridge1_001282 OCCCc1nc2cc(Cl)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C07 compound treatment 863907.0 285000.0 0.41 934136.0 326000.0 0.45 0.6076 0.9984 2070151 Maybridge1_001283 N/C(=N\O)/CC(=O)Nc1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C08 compound treatment 854330.0 275000.0 0.39 936482.0 328000.0 0.46 0.6003 0.997 2070152 Maybridge1_001284 CCOC(=O)c1cc(CC)sc1NC(=O)C(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C09 compound treatment 874271.0 295000.0 0.42 955518.0 347000.0 0.48 0.6391 0.9975 2070153 Maybridge1_001285 Cc1cc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C10 compound treatment 853945.0 275000.0 0.39 938230.0 330000.0 0.46 0.6016 0.9967 2070154 Maybridge1_001286 [O-][N+](=O)c1cnc(s1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C11 compound treatment 867969.0 289000.0 0.41 953932.0 345000.0 0.48 0.6312 0.9969 1249008 Maybridge1_001287 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C12 compound treatment 846622.0 268000.0 0.38 953714.0 345000.0 0.48 0.6095 0.9932 2070155 Maybridge1_001288 CCc1nnc(N/C=N/O)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C13 compound treatment 857174.0 278000.0 0.4 937164.0 329000.0 0.46 0.6038 0.9973 2070156 Maybridge1_001289 CN(C)/C=N/S(=O)(=O)c1cc(Cl)c(Oc2ccc(cc2)[N+](=O)[O-])c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C14 compound treatment 864549.0 285000.0 0.41 945765.0 337000.0 0.47 0.6197 0.9973 2070157 Maybridge1_001290 Cc1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C15 compound treatment 873330.0 294000.0 0.42 958362.0 350000.0 0.49 0.6409 0.9971 2070158 Maybridge1_001291 [O-][N+](=O)c1cc(cc(Br)c1OC(=O)c2ccccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C16 compound treatment 849498.0 270000.0 0.38 946748.0 338000.0 0.47 0.6055 0.9948 2070159 Maybridge1_001292 Cc1cc(OS(=O)(=O)c2ccc(F)c(Cl)c2)n(n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C17 compound treatment 886455.0 307000.0 0.44 967242.0 359000.0 0.5 0.6629 0.9977 2070160 Maybridge1_001293 FC(F)(F)c1cc(Br)c2ncc(nc2c1)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C18 compound treatment 854943.0 276000.0 0.39 905067.0 297000.0 0.41 0.5699 0.9996 2070161 Maybridge1_001294 Fc1cccc(Cl)c1C(=O)NC(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C19 compound treatment 847209.0 268000.0 0.38 957555.0 349000.0 0.49 0.6139 0.9927 2070162 Maybridge1_001295 COCCCNC(=S)NNC(=O)c1cc(OC)c(OC)c(OC)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C20 compound treatment 821890.0 243000.0 0.35 894851.0 286000.0 0.4 0.5266 0.9974 2070163 Maybridge1_001296 Oc1cc(ccc1[N+](=O)[O-])N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C21 compound treatment 858645.0 280000.0 0.4 936210.0 328000.0 0.46 0.6043 0.9976 2070164 Maybridge1_001297 Brc1csc(/C=C\2/SC(=S)NC2=O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C22 compound treatment 799992.0 221000.0 0.31 879976.0 271000.0 0.38 0.4899 0.9957 2070165 Maybridge1_001298 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)C(=O)c3c(F)cccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C23 mock treatment 857737.0 279000.0 0.4 929120.0 321000.0 0.45 0.5964 0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 C24 mock treatment 156574.0 -423000.0 -0.6 161865.0 -447000.0 -0.62 -0.8653 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D01 compound treatment 874145.0 295000.0 0.42 853628.0 245000.0 0.34 0.5385 0.9948 1295753 Maybridge1_001299 Cc1cc(c(C)cc1Cl)S(=O)(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D02 compound treatment 873789.0 295000.0 0.42 913493.0 305000.0 0.43 0.5971 1.0 2070166 Maybridge1_001300 CCCC1=NN(C(=O)C1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D03 compound treatment 888691.0 310000.0 0.44 952341.0 344000.0 0.48 0.6504 0.9991 2070167 Maybridge1_001301 [O-][N+](=O)c1cc(ccc1NCC2CC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D04 compound treatment 874533.0 295000.0 0.42 972141.0 364000.0 0.51 0.6557 0.9956 2070168 Maybridge1_001302 CSc1ncccc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D05 compound treatment 863700.0 285000.0 0.4 982047.0 374000.0 0.52 0.6546 0.9922 2070169 Maybridge1_001303 CN(C)/C=N/c1nnc(Sc2nc3c(Cl)cc(Cl)cc3s2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D06 compound treatment 891752.0 313000.0 0.44 993045.0 385000.0 0.54 0.6937 0.9957 2070170 Maybridge1_001304 Clc1cc(Cl)cc(c1)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D07 compound treatment 943344.0 364000.0 0.52 1032384.0 424000.0 0.59 0.7843 0.9978 2070171 Maybridge1_001305 Clc1cc(Cl)cc(OS(=O)(=O)c2cccc(c2)S(=O)(=O)Oc3cc(Cl)cc(Cl)c3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D08 compound treatment 924788.0 346000.0 0.49 967765.0 359000.0 0.5 0.702 1.0 2070172 Maybridge1_001306 CCCc1cc(O)nc(SCC(=O)Nc2ccc(F)c(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D09 compound treatment 957725.0 379000.0 0.54 1019801.0 411000.0 0.57 0.7864 0.9995 1009028 Maybridge1_001307 Clc1ccc(NC(=O)c2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D10 compound treatment 906071.0 327000.0 0.46 1002918.0 394000.0 0.55 0.7178 0.9965 2070173 Maybridge1_001308 Cc1cc(OC(=O)c2nn(nc2C)c3ccccc3)n(n1)c4cccc(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D11 compound treatment 901737.0 323000.0 0.46 1033067.0 425000.0 0.59 0.7432 0.992 1258378 Maybridge1_001309 CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D12 compound treatment 904863.0 326000.0 0.46 951292.0 343000.0 0.48 0.6657 0.9999 2070174 Maybridge1_001310 FC(F)(F)c1cccc(Sc2ncccc2C(=O)Nc3ccc(Cl)cc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D13 compound treatment 943400.0 364000.0 0.52 1017524.0 409000.0 0.57 0.7697 0.9988 2070175 Maybridge1_001311 Cc1cc(SCc2c(Cl)cccc2Cl)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D14 compound treatment 934924.0 356000.0 0.51 979348.0 371000.0 0.52 0.7236 0.9999 2070176 Maybridge1_001312 CN(C(=O)CSc1ccc(Cl)cc1)c2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D15 compound treatment 941055.0 362000.0 0.51 1058027.0 450000.0 0.63 0.8073 0.9952 2070177 Maybridge1_001313 CC(=O)NCCSc1cc(C)c(Cl)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D16 compound treatment 947018.0 368000.0 0.52 1007016.0 399000.0 0.56 0.763 0.9995 2070178 Maybridge1_001314 Cc1ccc([N+](=O)[O-])c(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D17 compound treatment 981160.0 402000.0 0.57 1026194.0 418000.0 0.58 0.8163 1.0 2070179 Maybridge1_001315 COc1cc(cc(Br)c1O)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D18 compound treatment 898782.0 320000.0 0.45 963920.0 355000.0 0.5 0.672 0.9991 2070180 Maybridge1_001316 OC(=O)c1ccc(c(c1)[N+](=O)[O-])S(=O)(=O)c2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D19 compound treatment 953677.0 375000.0 0.53 996870.0 388000.0 0.54 0.7597 1.0 1469626 Maybridge1_001317 OC(=O)c1cccnc1SCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D20 compound treatment 913432.0 334000.0 0.48 978575.0 370000.0 0.52 0.7012 0.9992 2070181 Maybridge1_001318 CSC(=NS(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D21 compound treatment 947789.0 369000.0 0.52 1011501.0 403000.0 0.56 0.7682 0.9994 1678057 Maybridge1_001319 CCSc1ncccc1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D22 compound treatment 889100.0 310000.0 0.44 977098.0 369000.0 0.51 0.6753 0.9971 2070182 Maybridge1_001320 Nc1ccccc1C(=O)NNC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D23 mock treatment 939234.0 360000.0 0.51 982748.0 374000.0 0.52 0.7313 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 D24 mock treatment 130045.0 -449000.0 -0.64 162358.0 -446000.0 -0.62 -0.8915 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E01 compound treatment 860535.0 281000.0 0.4 873964.0 265000.0 0.37 0.5448 0.9992 2070183 Maybridge1_001321 C/C(=N\Nc1nc(cs1)C(C)(C)C)/c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E02 compound treatment 877202.0 298000.0 0.42 911536.0 303000.0 0.42 0.5986 1.0 2070184 Maybridge1_001322 Nc1ccccc1C(=O)NCCCN2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E03 compound treatment 919582.0 340000.0 0.48 1022425.0 414000.0 0.58 0.7506 0.9962 2070185 Maybridge1_001323 CS/C(=N/N=C/c1cccs1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E04 compound treatment 955054.0 376000.0 0.53 998798.0 390000.0 0.54 0.763 1.0 1582393 Maybridge1_001324 COC(=O)c1cc(OC)c(OC)c(OC)c1NS(=O)(=O)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E05 compound treatment 921741.0 343000.0 0.49 1019531.0 411000.0 0.57 0.7499 0.9967 2070186 Maybridge1_001325 CCCc1nc2cc(C)c(C)cc2nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E06 compound treatment 932701.0 354000.0 0.5 998612.0 390000.0 0.54 0.7403 0.9992 1004703 Maybridge1_001326 OC(=O)c1ccccc1I 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E07 compound treatment 956520.0 377000.0 0.54 1034850.0 426000.0 0.59 0.8 0.9987 2070187 Maybridge1_001327 Cc1ccc(NC(=O)C/C(=N/O)/N)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E08 compound treatment 986804.0 408000.0 0.58 1026631.0 418000.0 0.58 0.8224 1.0 2070188 Maybridge1_001328 CCOC(=O)c1cc(CC)sc1NC(=O)C(Cl)(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E09 compound treatment 993711.0 415000.0 0.59 1038445.0 430000.0 0.6 0.841 1.0 1222255 Maybridge1_001329 Fc1ccc(NC(=O)Cc2ncon2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E10 compound treatment 961224.0 382000.0 0.54 997879.0 389000.0 0.54 0.7683 1.0 1363938 Maybridge1_001330 CCOC(=O)c1c(O)c2ccccc2n(C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E11 compound treatment 984281.0 405000.0 0.58 1030499.0 422000.0 0.59 0.8236 0.9999 2070189 Maybridge1_001331 NS(=O)(=O)c1ccc(Oc2c(Cl)cccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E12 compound treatment 929147.0 350000.0 0.5 1011362.0 403000.0 0.56 0.7493 0.9982 2070190 Maybridge1_001332 CN(C)/C=N/c1nnc(s1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E13 compound treatment 960517.0 381000.0 0.54 1023031.0 415000.0 0.58 0.7924 0.9995 2070191 Maybridge1_001333 FC(F)(F)c1ccc2nc(cnc2c1)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E14 compound treatment 952474.0 373000.0 0.53 1016686.0 408000.0 0.57 0.778 0.9994 2070192 Maybridge1_001334 Cc1cc(NC(=O)NC(=O)c2c(F)cccc2Cl)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E15 compound treatment 955820.0 377000.0 0.54 1049312.0 441000.0 0.61 0.8136 0.9976 2070193 Maybridge1_001335 CC(=O)OCc1csc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E16 compound treatment 951685.0 373000.0 0.53 1015040.0 407000.0 0.57 0.7756 0.9994 2070194 Maybridge1_001336 CN(C)/C=N/c1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E17 compound treatment 905874.0 327000.0 0.46 1010219.0 402000.0 0.56 0.7248 0.9957 2070195 Maybridge1_001337 CC(O)CNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E18 compound treatment 922385.0 343000.0 0.49 999709.0 391000.0 0.55 0.731 0.9985 1525564 Maybridge1_001338 Clc1cc(Cl)cc(c1)S(=O)(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E19 compound treatment 926687.0 348000.0 0.49 1038735.0 430000.0 0.6 0.7739 0.9954 1055254 Maybridge1_001339 OCCNc1ccc(cn1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E20 compound treatment 918096.0 339000.0 0.48 989666.0 381000.0 0.53 0.7168 0.9988 2070196 Maybridge1_001340 CC1CN(CC(C)O1)c2ccc([N+](=O)[O-])c(O)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E21 compound treatment 960518.0 381000.0 0.54 1044906.0 436000.0 0.61 0.814 0.9983 2070197 Maybridge1_001341 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/C(=N\O)/C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E22 compound treatment 922296.0 343000.0 0.49 991997.0 384000.0 0.53 0.7233 0.999 2070198 Maybridge1_001342 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)C(=O)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E23 mock treatment 957004.0 378000.0 0.54 1038266.0 430000.0 0.6 0.8039 0.9985 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 E24 mock treatment 185125.0 -394000.0 -0.56 169839.0 -439000.0 -0.61 -0.8287 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F01 compound treatment 896606.0 318000.0 0.45 869595.0 261000.0 0.36 0.5768 0.9943 2070199 Maybridge1_001343 N/C(=N\O)/CS(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F02 compound treatment 899653.0 321000.0 0.46 942368.0 334000.0 0.47 0.6516 0.9999 1573123 Maybridge1_001344 Clc1ccc(cc1)C(=O)N2CCN(CC2)C(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F03 compound treatment 942865.0 364000.0 0.52 1022283.0 414000.0 0.58 0.7739 0.9985 1428169 Maybridge1_001345 Cc1cc(O)c2cc(F)cc(F)c2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F04 compound treatment 934037.0 355000.0 0.5 1001679.0 393000.0 0.55 0.7447 0.9991 1002355 Maybridge1_001346 CC(=O)Nc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F05 compound treatment 952670.0 374000.0 0.53 1017715.0 409000.0 0.57 0.7793 0.9994 1357459 Maybridge1_001347 Cc1cc(Sc2nnc(N)s2)c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F06 compound treatment 924725.0 346000.0 0.49 932674.0 324000.0 0.45 0.6673 0.9991 2070200 Maybridge1_001348 [O-][N+](=O)c1cccnc1Oc2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F07 compound treatment 999108.0 420000.0 0.6 1027669.0 419000.0 0.58 0.8358 0.9999 1567712 Maybridge1_001349 Cc1cc(C)c2nc(C)cc(O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F08 compound treatment 972522.0 393000.0 0.56 1032747.0 424000.0 0.59 0.814 0.9996 1275354 Maybridge1_001350 O=C(Nc1ccccc1C(=O)NC2CCCCNC2=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F09 compound treatment 1046276.0 467000.0 0.66 1053272.0 445000.0 0.62 0.9084 0.9994 2070201 Maybridge1_001351 Clc1ccc(/C=C/2\C(=O)ON=C2c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F10 compound treatment 947241.0 368000.0 0.52 1003585.0 395000.0 0.55 0.7599 0.9997 1686372 Maybridge1_001352 O=C(CC#N)NC1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F11 compound treatment 1013337.0 434000.0 0.62 1014742.0 406000.0 0.57 0.8373 0.9991 1741154 Maybridge1_001353 CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(F)cc2F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F12 compound treatment 959190.0 380000.0 0.54 990174.0 382000.0 0.53 0.7586 1.0 2070202 Maybridge1_001354 [O-][N+](=O)c1ccc(cc1OC(=O)c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F13 compound treatment 951243.0 372000.0 0.53 1005140.0 397000.0 0.55 0.7654 0.9998 2070203 Maybridge1_001355 Cc1cc(SCc2cccc(F)c2)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F14 compound treatment 952990.0 374000.0 0.53 983267.0 375000.0 0.52 0.7456 1.0 2070204 Maybridge1_001356 Clc1ccc(cc1)C(=O)Nc2ncccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F15 compound treatment 966855.0 388000.0 0.55 1044364.0 436000.0 0.61 0.8198 0.9988 2070205 Maybridge1_001357 Clc1cn[nH]c(=O)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F16 compound treatment 907653.0 329000.0 0.47 977355.0 369000.0 0.51 0.6942 0.9988 2070206 Maybridge1_001358 OC(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F17 compound treatment 985637.0 407000.0 0.58 1033533.0 425000.0 0.59 0.828 0.9999 2070207 Maybridge1_001359 CCOC(=O)CC(=O)CSc1cc(C)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F18 compound treatment 915102.0 336000.0 0.48 982797.0 374000.0 0.52 0.707 0.999 1863471 Maybridge1_001360 OC(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F19 compound treatment 951375.0 372000.0 0.53 1060550.0 452000.0 0.63 0.8202 0.9962 2070208 Maybridge1_001361 CN(C)/C=C\1/C(=O)NN=C1CSc2cc(C)c(Cl)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F20 compound treatment 980692.0 402000.0 0.57 995915.0 387000.0 0.54 0.7859 0.9996 2070209 Maybridge1_001362 FC(F)(F)c1cc(c2cccs2)n(n1)c3ccc(cc3)S(=O)(=O)NC(=S)Nc4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F21 compound treatment 983117.0 404000.0 0.57 1033487.0 425000.0 0.59 0.8254 0.9999 1783937 Maybridge1_001363 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F22 compound treatment 896995.0 318000.0 0.45 962989.0 355000.0 0.49 0.6693 0.999 2070210 Maybridge1_001364 COc1ccc(Br)c(c1)C(=O)NNC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F23 mock treatment 964961.0 386000.0 0.55 1029566.0 421000.0 0.59 0.8033 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 F24 mock treatment 138668.0 -440000.0 -0.63 172657.0 -436000.0 -0.61 -0.8727 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G01 compound treatment 853378.0 274000.0 0.39 911699.0 303000.0 0.42 0.5749 0.9992 2070211 Maybridge1_001365 CS/C(=N/N=C/c1ccc(Cl)cc1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G02 compound treatment 868500.0 289000.0 0.41 911044.0 303000.0 0.42 0.5894 0.9999 2070212 Maybridge1_001366 NS(=O)(=O)c1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G03 compound treatment 888633.0 310000.0 0.44 1010483.0 402000.0 0.56 0.7077 0.9928 2070213 Maybridge1_001367 [O-][N+](=O)c1ccc(Oc2ccc(cc2)c3ccc(Oc4ccc(cn4)[N+](=O)[O-])cc3)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G04 compound treatment 902302.0 323000.0 0.46 917695.0 309000.0 0.43 0.63 0.9995 1737783 Maybridge1_001368 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c2cc3ccccc3oc2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G05 compound treatment 935920.0 357000.0 0.51 1001772.0 393000.0 0.55 0.7467 0.9992 2070214 Maybridge1_001369 [O-][N+](=O)c1cc(ccc1Oc2ccc(F)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G06 compound treatment 906699.0 328000.0 0.47 933811.0 325000.0 0.45 0.6503 0.9999 2070215 Maybridge1_001370 CN(C)/C=N/c1cc(C)on1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G07 compound treatment 899972.0 321000.0 0.46 1005412.0 397000.0 0.55 0.7141 0.9954 2070216 Maybridge1_001371 CSc1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G08 compound treatment 947975.0 369000.0 0.52 1003291.0 395000.0 0.55 0.7603 0.9997 1380289 Maybridge1_001372 Cc1nn(nc1C(=O)Nc2nnc(s2)C3CC3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G09 compound treatment 934371.0 355000.0 0.51 953385.0 345000.0 0.48 0.6974 0.9997 2070217 Maybridge1_001373 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(Cl)cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G10 compound treatment 901822.0 323000.0 0.46 963872.0 355000.0 0.5 0.675 0.9993 2070218 Maybridge1_001374 CSC(=S)Nc1ccc(F)cc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G11 compound treatment 933252.0 354000.0 0.5 991740.0 383000.0 0.53 0.7341 0.9996 2070219 Maybridge1_001375 FC(F)(F)c1ccc2nc3C(=O)c4ccccc4-c3nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G12 compound treatment 908337.0 329000.0 0.47 976347.0 368000.0 0.51 0.6939 0.999 2070220 Maybridge1_001376 CN(C)/C=N/c1nnc(C)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G13 compound treatment 930535.0 351000.0 0.5 1004941.0 396000.0 0.55 0.7444 0.9987 1052629 Maybridge1_001377 COc1cc(C(=O)O)c([N+](=O)[O-])c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G14 compound treatment 925514.0 346000.0 0.49 986602.0 378000.0 0.53 0.7213 0.9994 2070221 Maybridge1_001378 Cc1onc(NC(=O)NC(=O)c2c(F)cccc2Cl)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G15 compound treatment 937237.0 358000.0 0.51 1019014.0 411000.0 0.57 0.765 0.9983 2070222 Maybridge1_001379 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(cc2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G16 compound treatment 889075.0 310000.0 0.44 985424.0 377000.0 0.53 0.6835 0.9962 2070223 Maybridge1_001380 CN(C)/C=N/c1nnc(Sc2ccc(cn2)[N+](=O)[O-])s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G17 compound treatment 937156.0 358000.0 0.51 1007510.0 399000.0 0.56 0.7536 0.999 1500459 Maybridge1_001381 COc1cc2c(=O)n(CC=C)c(=S)[nH]c2c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G18 compound treatment 892362.0 313000.0 0.45 997529.0 389000.0 0.54 0.6987 0.9952 1441622 Maybridge1_001382 Cc1cc(c(C)cc1Cl)S(=O)(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G19 compound treatment 926108.0 347000.0 0.49 1031744.0 423000.0 0.59 0.7664 0.996 2070224 Maybridge1_001383 [O-][N+](=O)c1ccc(o1)C(=O)OCCNc2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G20 compound treatment 869595.0 291000.0 0.41 916077.0 308000.0 0.43 0.5955 0.9998 2070225 Maybridge1_001384 Oc1cc(ccc1[N+](=O)[O-])N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G21 compound treatment 899955.0 321000.0 0.46 994467.0 386000.0 0.54 0.7033 0.9966 2070226 Maybridge1_001385 CC(C)c1ccc(cc1)S(=O)(=O)Oc2cccc3ccc(C)nc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G22 compound treatment 876885.0 298000.0 0.42 990651.0 382000.0 0.53 0.6764 0.9935 2070227 Maybridge1_001386 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G23 mock treatment 937537.0 358000.0 0.51 987379.0 379000.0 0.53 0.7341 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 G24 mock treatment 159717.0 -419000.0 -0.6 139590.0 -469000.0 -0.65 -0.8841 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H01 compound treatment 853273.0 274000.0 0.39 872738.0 264000.0 0.37 0.5363 0.9996 2070228 Maybridge1_001387 Cc1cc(C)n(n1)c2ccc(Sc3ccc(Cl)cc3)nn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H02 compound treatment 898791.0 320000.0 0.45 945839.0 337000.0 0.47 0.6542 0.9999 2070229 Maybridge1_001388 CC/1=NN(C(=O)\C1=C/c2cc(Br)cs2)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H03 compound treatment 917686.0 339000.0 0.48 981458.0 373000.0 0.52 0.7083 0.9993 2070230 Maybridge1_001389 Cc1nn(c2ccccc2)c3oc(=O)cc(C)c13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H04 compound treatment 881874.0 303000.0 0.43 917154.0 309000.0 0.43 0.6089 1.0 2070231 Maybridge1_001390 [O-][N+](=O)c1ccc(Oc2ccc(cc2)C3SCCS3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H05 compound treatment 938549.0 359000.0 0.51 979766.0 371000.0 0.52 0.7276 1.0 2070232 Maybridge1_001391 Cc1n[nH]c2oc(=O)cc(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H06 compound treatment 871692.0 293000.0 0.42 862380.0 254000.0 0.35 0.5446 0.9968 2070233 Maybridge1_001392 [O-][N+](=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H07 compound treatment 938531.0 359000.0 0.51 1008227.0 400000.0 0.56 0.7557 0.9991 1033256 Maybridge1_001393 CC1=NN(C(=O)CC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H08 compound treatment 920143.0 341000.0 0.49 1004857.0 396000.0 0.55 0.7339 0.9979 1408705 Maybridge1_001394 O=C(Nc1ccccc1C(=O)NC2CCCCNC2=O)c3cc4ccccc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H09 compound treatment 970538.0 391000.0 0.56 1032803.0 424000.0 0.59 0.8121 0.9995 2070234 Maybridge1_001395 CC/1=NN(C(=O)\C1=C/c2ccc(Cl)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H10 compound treatment 898030.0 319000.0 0.45 953941.0 345000.0 0.48 0.6614 0.9995 2070235 Maybridge1_001396 Cc1nn(nc1c2nnc(o2)c3ccc(Cl)cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H11 compound treatment 943114.0 364000.0 0.52 1002760.0 394000.0 0.55 0.7549 0.9995 2070236 Maybridge1_001397 CCOC(=O)Cc1csc(N/C=N/O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H12 compound treatment 928727.0 350000.0 0.5 985505.0 377000.0 0.53 0.7234 0.9996 2070237 Maybridge1_001398 [O-][N+](=O)c1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H13 compound treatment 957697.0 379000.0 0.54 960947.0 352000.0 0.49 0.7283 0.999 2070238 Maybridge1_001399 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Cc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H14 compound treatment 932440.0 353000.0 0.5 993444.0 385000.0 0.54 0.735 0.9995 1441513 Maybridge1_001400 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H15 compound treatment 956939.0 378000.0 0.54 990743.0 382000.0 0.53 0.7569 1.0 2070239 Maybridge1_001401 Cc1cc(SCC#N)c(C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H16 compound treatment 942203.0 363000.0 0.52 987915.0 379000.0 0.53 0.7393 0.9999 2070240 Maybridge1_001402 Clc1ccc(cc1)C(=O)Nc2cnccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H17 compound treatment 948310.0 369000.0 0.53 1003875.0 395000.0 0.55 0.7612 0.9997 2070241 Maybridge1_001403 Cc1cc(SCC2=NNC(=O)C2)c(C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H18 compound treatment 900685.0 322000.0 0.46 915329.0 307000.0 0.43 0.626 0.9995 2070242 Maybridge1_001404 Cc1nn(c2cccc(Cl)c2)c3oc(=O)cc(c13)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H19 compound treatment 952698.0 374000.0 0.53 974377.0 366000.0 0.51 0.7365 0.9998 1030549 Maybridge1_001405 O=C1N(CC#N)S(=O)(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H20 compound treatment 887687.0 309000.0 0.44 967378.0 359000.0 0.5 0.6643 0.9978 2070243 Maybridge1_001406 NS(=O)(=O)c1cc(Cl)sc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H21 compound treatment 948208.0 369000.0 0.52 992760.0 384000.0 0.54 0.7502 0.9999 2070244 Maybridge1_001407 CCCC(=O)c1cc2cc(ccc2oc1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H22 compound treatment 912810.0 334000.0 0.47 937628.0 329000.0 0.46 0.6602 0.9999 2070245 Maybridge1_001408 COc1cccc(c1)C(=O)NNC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H23 mock treatment 936010.0 357000.0 0.51 991702.0 383000.0 0.53 0.7368 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 H24 mock treatment 129752.0 -449000.0 -0.64 137558.0 -471000.0 -0.66 -0.9163 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I01 compound treatment 883431.0 304000.0 0.43 900468.0 292000.0 0.41 0.594 0.9995 2070246 Maybridge1_001409 CS/C(=N/N=C/c1c(F)cccc1Cl)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I02 compound treatment 864426.0 285000.0 0.41 941183.0 333000.0 0.46 0.615 0.9978 2070247 Maybridge1_001410 CC(=O)C(C)(C)OC(=O)N1CCOCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I03 compound treatment 905382.0 326000.0 0.46 998271.0 390000.0 0.54 0.7125 0.9969 1019766 Maybridge1_001411 CC(=O)Nc1ccc(C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I04 compound treatment 867010.0 288000.0 0.41 1005443.0 397000.0 0.55 0.681 0.989 1658637 Maybridge1_001412 CC1CN(CC(C)O1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I05 compound treatment 905170.0 326000.0 0.46 1033487.0 425000.0 0.59 0.747 0.9926 2070248 Maybridge1_001413 Cc1cccc(Cl)c1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I06 compound treatment 934643.0 356000.0 0.51 971749.0 363000.0 0.51 0.7158 1.0 1442310 Maybridge1_001414 Clc1ccc(cc1Cl)C(=O)CSC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I07 compound treatment 945904.0 367000.0 0.52 1047729.0 439000.0 0.61 0.802 0.9968 2070249 Maybridge1_001415 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I08 compound treatment 931281.0 352000.0 0.5 1030136.0 422000.0 0.59 0.77 0.9968 2070250 Maybridge1_001416 Cc1nnc(NC(=O)c2nn(nc2C)c3ccccc3)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I09 compound treatment 957659.0 379000.0 0.54 1046174.0 438000.0 0.61 0.8123 0.998 2070251 Maybridge1_001417 Cc1cccc(C)c1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I10 compound treatment 927247.0 348000.0 0.5 1016493.0 408000.0 0.57 0.7525 0.9976 1165063 Maybridge1_001418 Nc1nc(=O)c2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I11 compound treatment 933332.0 354000.0 0.5 1018080.0 410000.0 0.57 0.7602 0.998 2070252 Maybridge1_001419 N/C(=N\OC(=O)c1cccs1)/CC(=O)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I12 compound treatment 910160.0 331000.0 0.47 1004763.0 396000.0 0.55 0.7237 0.9968 2070253 Maybridge1_001420 Cc1nnc(N/C=N/O)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I13 compound treatment 924450.0 345000.0 0.49 1022262.0 414000.0 0.58 0.7554 0.9968 2070254 Maybridge1_001421 NC(=O)NCc1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I14 compound treatment 913692.0 335000.0 0.48 1034395.0 426000.0 0.59 0.7565 0.994 2070255 Maybridge1_001422 Cc1onc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I15 compound treatment 935276.0 356000.0 0.51 1019187.0 411000.0 0.57 0.7632 0.9981 2070256 Maybridge1_001423 CC(C)(C)c1ccc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I16 compound treatment 901561.0 322000.0 0.46 979894.0 371000.0 0.52 0.6906 0.9982 2070257 Maybridge1_001424 CN(C)/C=N/c1nnc(Sc2ncccc2[N+](=O)[O-])s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I17 compound treatment 898741.0 320000.0 0.45 998209.0 390000.0 0.54 0.7058 0.996 2070258 Maybridge1_001425 OCCNc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I18 compound treatment 880812.0 302000.0 0.43 916180.0 308000.0 0.43 0.6069 1.0 1236124 Maybridge1_001426 S=C1NCN(CC2CC2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I19 compound treatment 939096.0 360000.0 0.51 1008373.0 400000.0 0.56 0.7564 0.9991 1158168 Maybridge1_001427 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I20 compound treatment 905797.0 327000.0 0.46 1002708.0 394000.0 0.55 0.7173 0.9965 1229472 Maybridge1_001428 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I21 compound treatment 955007.0 376000.0 0.53 1032371.0 424000.0 0.59 0.7961 0.9987 1694034 Maybridge1_001429 CN1C(NC(=O)c2ccccc12)c3cc(Br)cs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I22 compound treatment 886406.0 307000.0 0.44 968426.0 360000.0 0.5 0.664 0.9976 2070259 Maybridge1_001430 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(F)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I23 mock treatment 963613.0 385000.0 0.55 1023356.0 415000.0 0.58 0.7958 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 I24 mock treatment 153368.0 -426000.0 -0.61 151933.0 -457000.0 -0.64 -0.8783 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J01 compound treatment 875374.0 296000.0 0.42 878767.0 270000.0 0.38 0.5645 0.9985 2070260 Maybridge1_001431 Nc1ccc(Cl)cc1C(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J02 compound treatment 908516.0 329000.0 0.47 915102.0 307000.0 0.43 0.6337 0.999 2070261 Maybridge1_001432 Oc1cc(Sc2ccccc2)ccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J03 compound treatment 894420.0 315000.0 0.45 954167.0 346000.0 0.48 0.658 0.9993 2070262 Maybridge1_001433 Cc1nn(C)c2oc(=O)cc(c12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J04 compound treatment 875873.0 297000.0 0.42 935140.0 327000.0 0.46 0.6206 0.9993 1021654 Maybridge1_001434 CC(=O)Nc1ccc(cc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J05 compound treatment 896197.0 317000.0 0.45 984632.0 376000.0 0.52 0.6898 0.9972 2070263 Maybridge1_001435 CC1CCN(CC1)c2ccc([N+](=O)[O-])c(Oc3nc4c(Cl)cc(Cl)cc4s3)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J06 compound treatment 882493.0 303000.0 0.43 961904.0 353000.0 0.49 0.6536 0.9978 2070264 Maybridge1_001436 [O-][N+](=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J07 compound treatment 952764.0 374000.0 0.53 973190.0 365000.0 0.51 0.7354 0.9998 2070265 Maybridge1_001437 Clc1ccc(I)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J08 compound treatment 965607.0 387000.0 0.55 1008225.0 400000.0 0.56 0.7829 1.0 1424245 Maybridge1_001438 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NC3CCCCNC3=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J09 compound treatment 984229.0 405000.0 0.58 1007636.0 399000.0 0.56 0.801 0.9999 2070266 Maybridge1_001439 Cc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J10 compound treatment 903678.0 325000.0 0.46 913579.0 305000.0 0.43 0.6273 0.9992 2070267 Maybridge1_001440 Cc1nn(nc1c2nnc(o2)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J11 compound treatment 921372.0 342000.0 0.49 987167.0 379000.0 0.53 0.7177 0.9992 2070268 Maybridge1_001441 Cc1ccc2cc(ccc2n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J12 compound treatment 928700.0 350000.0 0.5 959915.0 351000.0 0.49 0.6981 1.0 2070269 Maybridge1_001442 Clc1ccc(NC(=O)CC#N)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J13 compound treatment 946414.0 367000.0 0.52 1034541.0 426000.0 0.59 0.7896 0.9979 1013980 Maybridge1_001443 OS(=O)(=O)c1cccc2cccc(Cl)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J14 compound treatment 917886.0 339000.0 0.48 967727.0 359000.0 0.5 0.695 0.9998 2070270 Maybridge1_001444 O=C(CC#N)Nc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J15 compound treatment 942893.0 364000.0 0.52 980302.0 372000.0 0.52 0.7325 1.0 2070271 Maybridge1_001445 CSc1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J16 compound treatment 883083.0 304000.0 0.43 982357.0 374000.0 0.52 0.6744 0.9957 1160934 Maybridge1_001446 Clc1ccc(NC(=O)c2cnccn2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J17 compound treatment 926998.0 348000.0 0.49 1000557.0 392000.0 0.55 0.7365 0.9988 2070272 Maybridge1_001447 O=C1CC(=NN1)CSc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J18 compound treatment 913000.0 334000.0 0.47 956132.0 348000.0 0.48 0.6786 0.9999 2070273 Maybridge1_001448 Cc1nn(c2ccccc2)c3oc(=O)cc(c13)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J19 compound treatment 923990.0 345000.0 0.49 990286.0 382000.0 0.53 0.7234 0.9992 1234815 Maybridge1_001449 CCSc1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J20 compound treatment 898799.0 320000.0 0.45 986643.0 378000.0 0.53 0.6944 0.9973 1422595 Maybridge1_001450 Fc1cccc(Cl)c1CN2c3ccccc3C(=O)CS2(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J21 compound treatment 919714.0 341000.0 0.48 1010698.0 402000.0 0.56 0.7392 0.9973 1531298 Maybridge1_001451 CCCC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J22 compound treatment 889509.0 310000.0 0.44 934724.0 326000.0 0.46 0.6339 0.9999 1487398 Maybridge1_001452 Fc1ccc(cc1F)C(=O)c2cc3ccccc3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J23 mock treatment 954261.0 375000.0 0.53 983317.0 375000.0 0.52 0.7469 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 J24 mock treatment 146453.0 -433000.0 -0.62 130171.0 -478000.0 -0.67 -0.9068 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K01 compound treatment 855928.0 277000.0 0.39 881647.0 273000.0 0.38 0.5478 0.9999 2070274 Maybridge1_001453 CS/C(=N/N=C/c1ccc(cc1)N(C)C)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K02 compound treatment 854565.0 275000.0 0.39 928986.0 321000.0 0.45 0.5931 0.9978 2070275 Maybridge1_001454 Clc1ccc2[nH]c(nc(=O)c2c1)c3cc(Br)cs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K03 compound treatment 887710.0 309000.0 0.44 1001647.0 393000.0 0.55 0.6981 0.9939 1143063 Maybridge1_001455 COc1ccc(Oc2cc(C)nc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K04 compound treatment 857296.0 278000.0 0.4 978385.0 370000.0 0.52 0.6446 0.9914 2070276 Maybridge1_001456 O=C(CC#N)N1CCSCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K05 compound treatment 851762.0 273000.0 0.39 984952.0 376000.0 0.53 0.6455 0.9889 1037135 Maybridge1_001457 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K06 compound treatment 852693.0 274000.0 0.39 964008.0 356000.0 0.5 0.6258 0.9928 2070277 Maybridge1_001458 Cc1onc(NC(=O)c2ccc(o2)[N+](=O)[O-])c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K07 compound treatment 927897.0 349000.0 0.5 984219.0 376000.0 0.52 0.7213 0.9996 2070278 Maybridge1_001459 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(OC)c(OC)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K08 compound treatment 897504.0 318000.0 0.45 996427.0 388000.0 0.54 0.7028 0.9961 1403130 Maybridge1_001460 CCc1nnc(NC(=O)c2nn(nc2C)c3ccccc3)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K09 compound treatment 897422.0 318000.0 0.45 1041637.0 433000.0 0.6 0.7473 0.9899 2070279 Maybridge1_001461 CSc1ccc(Oc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K10 compound treatment 849280.0 270000.0 0.38 964026.0 356000.0 0.5 0.6223 0.992 2070280 Maybridge1_001462 CC(=O)c1cc2cc(Br)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K11 compound treatment 788282.0 209000.0 0.3 863158.0 255000.0 0.36 0.4615 0.9961 2070281 Maybridge1_001463 COc1ccc(OC)c2nc3-c4ccccc4C(=O)c3nc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K12 compound treatment 861602.0 283000.0 0.4 977080.0 369000.0 0.51 0.6476 0.9926 1537115 Maybridge1_001464 Fc1ccc(NC(=O)Cc2nn[nH]n2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K13 compound treatment 877202.0 298000.0 0.42 986048.0 378000.0 0.53 0.6721 0.9942 2070282 Maybridge1_001465 CC(=O)C1=CN=C(SC1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K14 compound treatment 851955.0 273000.0 0.39 988775.0 380000.0 0.53 0.6494 0.9882 2070283 Maybridge1_001466 COC(=O)CS(=O)(=O)c1cc(C)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K15 compound treatment 905950.0 327000.0 0.46 996314.0 388000.0 0.54 0.7112 0.9971 1046920 Maybridge1_001467 COC(=O)c1cc(OC)c(OC)c(OC)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K16 compound treatment 871275.0 292000.0 0.42 969184.0 361000.0 0.5 0.6495 0.9955 2070284 Maybridge1_001468 CCc1ccc(cc1)c2ccc(OC(=O)c3c(Br)cc(cc3[N+](=O)[O-])C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K17 compound treatment 885041.0 306000.0 0.44 995205.0 387000.0 0.54 0.689 0.9943 2070285 Maybridge1_001469 CC(C)(CO)Nc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K18 compound treatment 894180.0 315000.0 0.45 965454.0 357000.0 0.5 0.6689 0.9986 1162688 Maybridge1_001470 Fc1ccc(cc1Cl)S(=O)(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K19 compound treatment 887506.0 308000.0 0.44 1013102.0 405000.0 0.56 0.7092 0.9922 2070286 Maybridge1_001471 OC(=O)CSc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K20 compound treatment 872084.0 293000.0 0.42 978108.0 370000.0 0.52 0.6592 0.9944 2070287 Maybridge1_001472 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)Nc2ccccc2C(=O)NCC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K21 compound treatment 928112.0 349000.0 0.5 1044736.0 436000.0 0.61 0.7812 0.9949 1227697 Maybridge1_001473 Brc1csc(c1)C2NC(=O)c3ccccc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K22 compound treatment 855344.0 276000.0 0.39 975726.0 367000.0 0.51 0.64 0.9914 2070288 Maybridge1_001474 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K23 mock treatment 915120.0 336000.0 0.48 995338.0 387000.0 0.54 0.7194 0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 K24 mock treatment 152855.0 -426000.0 -0.61 149816.0 -459000.0 -0.64 -0.8809 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L01 compound treatment 838040.0 259000.0 0.37 848797.0 240000.0 0.34 0.4974 0.9989 2070289 Maybridge1_001475 Nc1ccccc1C(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L02 compound treatment 862464.0 283000.0 0.4 866574.0 258000.0 0.36 0.5395 0.9984 2070290 Maybridge1_001476 Cc1cc(Sc2ccc([N+](=O)[O-])c(O)c2)c(C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L03 compound treatment 934127.0 355000.0 0.5 956786.0 348000.0 0.49 0.7005 0.9998 1174018 Maybridge1_001477 Cc1nc2ccc(Cl)cc2c(O)c1I 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L04 compound treatment 856840.0 278000.0 0.39 925993.0 318000.0 0.44 0.5924 0.9984 2070291 Maybridge1_001478 N#Cc1cccnc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L05 compound treatment 884652.0 306000.0 0.43 959400.0 351000.0 0.49 0.6533 0.9982 2070292 Maybridge1_001479 Cc1cc(C)n(n1)c2ccc(Sc3ccccn3)nn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L06 compound treatment 888642.0 310000.0 0.44 934561.0 326000.0 0.45 0.6329 0.9999 2070293 Maybridge1_001480 COc1cc(cc(Br)c1OS(=O)(=O)c2ccc(C)cc2)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L07 compound treatment 913700.0 335000.0 0.48 961636.0 353000.0 0.49 0.6848 0.9999 2070294 Maybridge1_001481 CN(C)/C=C/1\C(=NN(C1=O)c2ccccc2)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L08 compound treatment 889591.0 311000.0 0.44 883050.0 275000.0 0.38 0.583 0.9975 2070295 Maybridge1_001482 COc1cc(Sc2ccc(Cl)cc2)ccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L09 compound treatment 896829.0 318000.0 0.45 965096.0 357000.0 0.5 0.6712 0.9989 2070296 Maybridge1_001483 Fc1cccc(NC(=O)c2cccc(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L10 compound treatment 868703.0 290000.0 0.41 948440.0 340000.0 0.47 0.6265 0.9975 1412717 Maybridge1_001484 Fc1ccccc1NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L11 compound treatment 898506.0 319000.0 0.45 954978.0 346000.0 0.48 0.6629 0.9995 2070297 Maybridge1_001485 Cc1cc(Sc2ncccc2[N+](=O)[O-])c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L12 compound treatment 851122.0 272000.0 0.39 954969.0 346000.0 0.48 0.6153 0.9939 2070298 Maybridge1_001486 [O-][N+](=O)c1ccc(Oc2cc(ccc2[N+](=O)[O-])S(=O)(=O)c3ccccc3)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L13 compound treatment 882598.0 304000.0 0.43 950373.0 342000.0 0.48 0.6424 0.9988 2070299 Maybridge1_001487 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L14 compound treatment 872795.0 294000.0 0.42 966351.0 358000.0 0.5 0.6483 0.9961 1076266 Maybridge1_001488 Clc1ccc(NC(=O)c2cccnc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L15 compound treatment 895573.0 316000.0 0.45 952585.0 344000.0 0.48 0.6576 0.9995 2070300 Maybridge1_001489 Cc1cc(c(C)cc1Cl)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L16 compound treatment 880385.0 301000.0 0.43 941910.0 333000.0 0.47 0.6318 0.9992 2070301 Maybridge1_001490 Cc1ccc(Sc2ccc(cc2[N+](=O)[O-])C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L17 compound treatment 931002.0 352000.0 0.5 978456.0 370000.0 0.52 0.7187 0.9999 2070302 Maybridge1_001491 Clc1ccc(SCC2=NNC(=O)C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L18 compound treatment 882090.0 303000.0 0.43 940991.0 333000.0 0.46 0.6326 0.9993 1046560 Maybridge1_001492 COc1ccc(NC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L19 compound treatment 923195.0 344000.0 0.49 955111.0 347000.0 0.48 0.6879 1.0 2070303 Maybridge1_001493 CC(=O)CN1C(=O)c2ccccc2S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L20 compound treatment 880997.0 302000.0 0.43 972953.0 364000.0 0.51 0.663 0.9965 1450792 Maybridge1_001494 COC(=O)c1ccc(Cl)cc1N(Cc2ccccc2)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L21 compound treatment 923381.0 344000.0 0.49 962088.0 354000.0 0.49 0.6949 1.0 1377255 Maybridge1_001495 CCCC(=O)c1cc2cc(Br)ccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L22 compound treatment 902807.0 324000.0 0.46 972817.0 364000.0 0.51 0.6848 0.9988 1230653 Maybridge1_001496 Clc1ccc2C(=O)CS(=O)(=O)N(Cc3ccccc3)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L23 mock treatment 944525.0 365000.0 0.52 963526.0 355000.0 0.5 0.7176 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 L24 mock treatment 144577.0 -435000.0 -0.62 160985.0 -447000.0 -0.62 -0.8783 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M01 compound treatment 862965.0 284000.0 0.4 896855.0 288000.0 0.4 0.5699 1.0 2070304 Maybridge1_001497 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc(cc3)N(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M02 compound treatment 856247.0 277000.0 0.39 958248.0 350000.0 0.49 0.6236 0.9944 2070305 Maybridge1_001498 CC(=O)C(C)(C)OC(=O)NCCc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M03 compound treatment 891167.0 312000.0 0.44 1000166.0 392000.0 0.55 0.7001 0.9947 2070306 Maybridge1_001499 [O-][N+](=O)c1cccc(Cl)c1Oc2ccc(cc2)c3ccc(Oc4c(Cl)cccc4[N+](=O)[O-])cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M04 compound treatment 829609.0 251000.0 0.36 926278.0 318000.0 0.44 0.5653 0.9941 2070307 Maybridge1_001500 COC(=O)c1cc(OC)c(OC)c(OC)c1NS(=O)(=O)c2cc(OC)ccc2OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M05 compound treatment 847640.0 269000.0 0.38 995318.0 387000.0 0.54 0.6515 0.9857 2070308 Maybridge1_001501 COc1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M06 compound treatment 837110.0 258000.0 0.37 1002833.0 394000.0 0.55 0.6484 0.9806 2070309 Maybridge1_001502 COc1ccccc1NC(=O)/C=N/O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M07 compound treatment 901838.0 323000.0 0.46 975767.0 367000.0 0.51 0.6868 0.9985 2070310 Maybridge1_001503 [O-][N+](=O)c1cc(ccc1Oc2ccc(F)cc2F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M08 compound treatment 872250.0 293000.0 0.42 967174.0 359000.0 0.5 0.6485 0.9959 2070311 Maybridge1_001504 CSC1=NCCN1C(=O)c2nn(nc2C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M09 compound treatment 883341.0 304000.0 0.43 943796.0 335000.0 0.47 0.6366 0.9992 2070312 Maybridge1_001505 [O-][N+](=O)c1cc(ccc1Oc2ccc(cc2)c3ccccc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M10 compound treatment 866482.0 287000.0 0.41 961396.0 353000.0 0.49 0.637 0.9957 2070313 Maybridge1_001506 CN(C)/C=C(\C#N)/C(=O)Nc1ccc(C)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M11 compound treatment 888447.0 309000.0 0.44 1011214.0 403000.0 0.56 0.7083 0.9927 1452789 Maybridge1_001507 Cc1ccc2nc3C(=O)c4ccccc4-c3nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M12 compound treatment 856377.0 277000.0 0.39 946210.0 338000.0 0.47 0.6119 0.9961 1172166 Maybridge1_001508 Clc1cc(Cl)cc(NC(=O)Cc2nn[nH]n2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M13 compound treatment 895050.0 316000.0 0.45 1021009.0 413000.0 0.58 0.7246 0.9925 2070314 Maybridge1_001509 Nc1ccccc1C(=O)NNc2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M14 compound treatment 884004.0 305000.0 0.43 1006880.0 398000.0 0.56 0.6995 0.9925 2070315 Maybridge1_001510 COC(=O)CS(=O)(=O)c1cc(C)c(Cl)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M15 compound treatment 922578.0 343000.0 0.49 1026445.0 418000.0 0.58 0.7576 0.9961 2070316 Maybridge1_001511 Cc1onc(c1C(=O)Nc2ccccc2C(=O)NNc3c(Cl)cc(Cl)cc3Cl)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M16 compound treatment 877170.0 298000.0 0.42 949578.0 341000.0 0.48 0.6361 0.9983 1284149 Maybridge1_001512 O=C(NCC1CC1)c2cccnc2Oc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M17 compound treatment 908790.0 330000.0 0.47 1010378.0 402000.0 0.56 0.7279 0.9961 1482069 Maybridge1_001513 COc1cc(C(=O)O)c(NC(=O)C)c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M18 compound treatment 872794.0 294000.0 0.42 1008416.0 400000.0 0.56 0.6898 0.9898 1148165 Maybridge1_001514 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M19 compound treatment 909132.0 330000.0 0.47 979407.0 371000.0 0.52 0.6977 0.9988 2070317 Maybridge1_001515 COc1ccc(cc1)/C(=C/c2cc(Br)cs2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M20 compound treatment 839075.0 260000.0 0.37 979080.0 371000.0 0.52 0.6269 0.9865 2070318 Maybridge1_001516 CN(C)/C=N/S(=O)(=O)c1cc(C)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M21 compound treatment 888650.0 310000.0 0.44 979984.0 372000.0 0.52 0.6777 0.9967 2070319 Maybridge1_001517 CCCCCC(=O)c1cc(C)c(C)cc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M22 compound treatment 885058.0 306000.0 0.44 985867.0 377000.0 0.53 0.6799 0.9955 2070320 Maybridge1_001518 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M23 mock treatment 929818.0 351000.0 0.5 988198.0 380000.0 0.53 0.7272 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 M24 mock treatment 719951.0 141000.0 0.2 637149.0 28700.0 0.04 0.1699 0.8318 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N01 compound treatment 892362.0 313000.0 0.45 893312.0 285000.0 0.4 0.5959 0.9984 2070321 Maybridge1_001519 Fc1cccc(Cl)c1CN(NC(=O)NC(=O)c2c(F)cccc2Cl)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N02 compound treatment 882235.0 303000.0 0.43 911734.0 303000.0 0.42 0.6039 1.0 2070322 Maybridge1_001520 Oc1cc(ccc1[N+](=O)[O-])S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N03 compound treatment 897905.0 319000.0 0.45 970001.0 362000.0 0.5 0.6771 0.9986 2070323 Maybridge1_001521 Nc1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N04 compound treatment 893675.0 315000.0 0.45 956662.0 348000.0 0.49 0.6597 0.9992 2070324 Maybridge1_001522 Clc1ccc(cc1Cl)C(=O)CN2CCSC2=N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N05 compound treatment 902799.0 324000.0 0.46 977484.0 369000.0 0.51 0.6894 0.9985 2070325 Maybridge1_001523 N/C(=N\O)/CS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N06 compound treatment 850253.0 271000.0 0.39 897172.0 289000.0 0.4 0.5574 0.9998 2070326 Maybridge1_001524 CCc1nn2cc(nc2s1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N07 compound treatment 925958.0 347000.0 0.49 996972.0 388000.0 0.54 0.7319 0.9989 2070327 Maybridge1_001525 CC/1=NN(C(=O)\C1=C\c2c(C)nn(c2O)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N08 compound treatment 870159.0 291000.0 0.41 923575.0 315000.0 0.44 0.6034 0.9996 2070328 Maybridge1_001526 [O-][N+](=O)c1ccc(Sc2ccccc2)cc1OCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N09 compound treatment 904228.0 325000.0 0.46 970110.0 362000.0 0.5 0.6836 0.9991 1037692 Maybridge1_001527 O=C1CC(=NN1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N10 compound treatment 911639.0 333000.0 0.47 941900.0 333000.0 0.47 0.6632 1.0 2070329 Maybridge1_001528 CCCc1nn(C)c(O)c1C(=O)c2cc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N11 compound treatment 950177.0 371000.0 0.53 963566.0 355000.0 0.5 0.7233 0.9995 2070330 Maybridge1_001529 Cc1cc(Sc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N12 compound treatment 904592.0 326000.0 0.46 908336.0 300000.0 0.42 0.623 0.9987 2070331 Maybridge1_001530 CCOC(=O)C(NC(=O)c1nn(nc1C)c2ccccc2)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N13 compound treatment 908054.0 329000.0 0.47 955451.0 347000.0 0.48 0.673 0.9999 2070332 Maybridge1_001531 Clc1ccc(NC(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N14 compound treatment 891266.0 312000.0 0.44 987713.0 379000.0 0.53 0.6879 0.9962 1633510 Maybridge1_001532 Clc1ccc(NC(=O)c2cccnc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N15 compound treatment 905169.0 326000.0 0.46 991017.0 383000.0 0.53 0.7052 0.9976 2070333 Maybridge1_001533 N/C(=N\OS(=O)(=O)c1ccc(Cl)cc1)/c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N16 compound treatment 898883.0 320000.0 0.45 973503.0 365000.0 0.51 0.6816 0.9984 2070334 Maybridge1_001534 Cc1cc(Sc2ccc(cc2[N+](=O)[O-])C(=O)O)c(C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N17 compound treatment 930168.0 351000.0 0.5 974634.0 366000.0 0.51 0.7141 0.9999 2070335 Maybridge1_001535 CN(C)/C=C\1/C(=O)NN=C1CSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N18 compound treatment 899243.0 320000.0 0.46 968941.0 360000.0 0.5 0.6774 0.9988 2070336 Maybridge1_001536 Clc1ccc(cc1)c2nnnn2c3cnccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N19 compound treatment 935267.0 356000.0 0.51 976614.0 368000.0 0.51 0.7212 1.0 2070337 Maybridge1_001537 CN(C)/C=C\1/C(=O)NN=C1CSc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N20 compound treatment 907039.0 328000.0 0.47 953131.0 345000.0 0.48 0.6697 0.9999 2070338 Maybridge1_001538 COc1ccc(Br)c(c1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N21 compound treatment 933387.0 354000.0 0.5 997869.0 389000.0 0.54 0.7403 0.9993 2070339 Maybridge1_001539 CCCC(=O)c1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N22 compound treatment 922349.0 343000.0 0.49 968503.0 360000.0 0.5 0.7002 0.9999 2070340 Maybridge1_001540 [O-][N+](=O)c1ccccc1C(=O)NNC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N23 mock treatment 979775.0 401000.0 0.57 964827.0 356000.0 0.5 0.7543 0.9977 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 N24 mock treatment 709305.0 130000.0 0.19 726239.0 118000.0 0.16 0.2471 0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O01 compound treatment 854799.0 276000.0 0.39 888486.0 280000.0 0.39 0.5534 1.0 2070341 Maybridge1_001541 CS/C(=N/N=C/c1c(F)cccc1Cl)/N=C/N(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O02 compound treatment 848392.0 269000.0 0.38 880080.0 272000.0 0.38 0.5387 1.0 2070342 Maybridge1_001542 COc1ccc(CCNC(=O)OC(C)(C)C(=O)C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O03 compound treatment 831287.0 252000.0 0.36 901190.0 293000.0 0.41 0.5423 0.9979 2070343 Maybridge1_001543 Cc1ccc(N(CC=C)C2=NC(C)(C)C(=C)S2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O04 compound treatment 869916.0 291000.0 0.41 943280.0 335000.0 0.47 0.6226 0.9982 2070344 Maybridge1_001544 CC(C)(C)SCCNc1nc(Oc2ccc(Cl)cc2)nc(Oc3ccc(Cl)cc3)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O05 compound treatment 865999.0 287000.0 0.41 965308.0 357000.0 0.5 0.6404 0.9951 2070345 Maybridge1_001545 COC(=O)c1sc2ccccc2c1OS(=O)(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O06 compound treatment 836117.0 257000.0 0.37 904753.0 296000.0 0.41 0.5506 0.9981 2070346 Maybridge1_001546 OCCCCCNc1ccc(cn1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O07 compound treatment 918917.0 340000.0 0.48 988967.0 380000.0 0.53 0.717 0.9989 2070347 Maybridge1_001547 CSc1ncc(C#N)c2nc(nn12)c3ccc(cc3)N(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O08 compound treatment 866162.0 287000.0 0.41 907457.0 299000.0 0.42 0.5835 0.9999 2070348 Maybridge1_001548 CSC1=NCCCN1C(=O)c2nn(nc2C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O09 compound treatment 877449.0 298000.0 0.42 984059.0 376000.0 0.52 0.6704 0.9945 1555636 Maybridge1_001549 Clc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4ncccc4c(=O)c3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O10 compound treatment 824029.0 245000.0 0.35 885513.0 277000.0 0.39 0.5195 0.9987 2070349 Maybridge1_001550 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n(n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O11 compound treatment 864603.0 286000.0 0.41 955167.0 347000.0 0.48 0.629 0.9962 2070350 Maybridge1_001551 CCOC(=O)/C(=C/Nc1ccc2oc3ncccc3c(=O)c2c1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O12 compound treatment 827795.0 249000.0 0.35 911664.0 303000.0 0.42 0.5491 0.9961 2070351 Maybridge1_001552 COC(=O)CSc1cc(C)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O13 compound treatment 866201.0 287000.0 0.41 955470.0 347000.0 0.48 0.6309 0.9964 2070352 Maybridge1_001553 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Oc2ccc(F)cc2F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O14 compound treatment 852392.0 273000.0 0.39 907244.0 299000.0 0.42 0.5695 0.9994 2070353 Maybridge1_001554 [O-][N+](=O)c1cc(ccc1SCC(=O)Nc2ccc(F)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O15 compound treatment 895947.0 317000.0 0.45 977375.0 369000.0 0.51 0.6824 0.9978 1047215 Maybridge1_001555 COc1cc(C(=O)O)c(N)c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O16 compound treatment 873560.0 294000.0 0.42 959076.0 351000.0 0.49 0.6419 0.997 1739779 Maybridge1_001556 Fc1ccccc1C(=O)NC(=O)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O17 compound treatment 913760.0 335000.0 0.48 976130.0 368000.0 0.51 0.6991 0.9993 2070354 Maybridge1_001557 [O-][N+](=O)c1ccc(o1)c2nc3ccccc3c(=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O18 compound treatment 847305.0 268000.0 0.38 915555.0 307000.0 0.43 0.5725 0.9983 1274234 Maybridge1_001558 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O19 compound treatment 886170.0 307000.0 0.44 971964.0 363000.0 0.51 0.6673 0.9972 2070355 Maybridge1_001559 Fc1ccc(NC(=O)/C(=C/c2cc(Br)cs2)/C#N)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O20 compound treatment 850500.0 271000.0 0.39 963382.0 355000.0 0.49 0.6229 0.9924 1128554 Maybridge1_001560 Cc1nn(nc1C(=O)NC(=O)N2CCCC2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O21 compound treatment 925979.0 347000.0 0.49 987430.0 379000.0 0.53 0.7225 0.9994 2070356 Maybridge1_001561 Fc1ccc(cc1Cl)S(=O)(=O)NC(=N)CSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O22 compound treatment 882429.0 303000.0 0.43 933325.0 325000.0 0.45 0.6254 0.9997 2070357 Maybridge1_001562 COC(=O)c1sccc1OC(=O)c2cccnc2Oc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O23 mock treatment 911398.0 332000.0 0.47 948580.0 340000.0 0.47 0.6696 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 O24 mock treatment 221167.0 -358000.0 -0.51 588905.0 -19600.0 -0.03 -0.3792 -0.744 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P01 compound treatment 883042.0 304000.0 0.43 829972.0 221000.0 0.31 0.5241 0.9864 2070358 Maybridge1_001563 Fc1cccc(Cl)c1CN(NC(=O)C(Cl)(Cl)Cl)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P02 compound treatment 887002.0 308000.0 0.44 896230.0 288000.0 0.4 0.5934 0.9991 1489801 Maybridge1_001564 CSc1ncccc1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P03 compound treatment 890027.0 311000.0 0.44 871549.0 263000.0 0.37 0.5721 0.9957 2070359 Maybridge1_001565 Nc1nnc(Sc2nc3c(Cl)cc(Cl)cc3s2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P04 compound treatment 898849.0 320000.0 0.45 879992.0 272000.0 0.38 0.5893 0.9959 2070360 Maybridge1_001566 Cc1cc(c(C)cc1Cl)S(=O)(=O)Oc2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P05 compound treatment 914452.0 335000.0 0.48 896155.0 288000.0 0.4 0.6209 0.9963 1602461 Maybridge1_001567 Cc1ccc2nc3sc4ccc(Cl)cc4n3c(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P06 compound treatment 935766.0 357000.0 0.51 892230.0 284000.0 0.4 0.6385 0.9925 2070361 Maybridge1_001568 CC(C)(C)c1cn2nc(sc2n1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P07 compound treatment 912681.0 334000.0 0.47 896113.0 288000.0 0.4 0.6191 0.9965 2070362 Maybridge1_001569 CN(C)/C=C/1\C(=NN(C)C1=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P08 compound treatment 917354.0 338000.0 0.48 906477.0 298000.0 0.42 0.634 0.9973 2070363 Maybridge1_001570 Cc1nn(nc1C(=O)NNC(=O)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P09 compound treatment 906069.0 327000.0 0.46 855041.0 247000.0 0.34 0.572 0.989 2070364 Maybridge1_001571 Cc1n[nH]c2oc(=O)c([N+](=O)[O-])c(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P10 compound treatment 909029.0 330000.0 0.47 895849.0 287000.0 0.4 0.6152 0.9969 2070365 Maybridge1_001572 Clc1cccc(NC(=O)CC#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P11 compound treatment 937228.0 358000.0 0.51 875500.0 267000.0 0.37 0.6235 0.9882 2070366 Maybridge1_001573 Cc1cc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P12 compound treatment 923073.0 344000.0 0.49 4068251.0 3460000.0 4.83 3.758 0.7748 2070367 Maybridge1_001574 CCOC(=O)C(NC(=O)c1cc2ccccc2s1)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P13 compound treatment 936102.0 357000.0 0.51 932755.0 324000.0 0.45 0.6788 0.9983 1008534 Maybridge1_001575 O=C(CC#N)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P14 compound treatment 902640.0 324000.0 0.46 892601.0 284000.0 0.4 0.6056 0.9972 1518071 Maybridge1_001576 CCCC1=NN(C(=O)C1)c2ccc(cc2)S(=O)(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P15 compound treatment 900905.0 322000.0 0.46 888306.0 280000.0 0.39 0.5996 0.9969 2070368 Maybridge1_001577 Cc1ccc(cc1)S(=O)(=O)O/N=C(\N)/c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P16 compound treatment 926447.0 347000.0 0.49 907552.0 299000.0 0.42 0.6442 0.9965 2070369 Maybridge1_001578 Cc1ccc(cc1)S(=O)(=O)c2ccc(cc2[N+](=O)[O-])C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P17 compound treatment 950307.0 371000.0 0.53 914089.0 306000.0 0.43 0.6747 0.9944 1484466 Maybridge1_001579 CCCSc1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P18 compound treatment 932026.0 353000.0 0.5 918952.0 310000.0 0.43 0.6611 0.9973 2070370 Maybridge1_001580 Cc1cc(=O)oc2n(nc(c12)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P19 compound treatment 938485.0 359000.0 0.51 926615.0 318000.0 0.44 0.6751 0.9975 2070371 Maybridge1_001581 CN(C)/C=C\1/C(=O)NN=C1CSc2cc(C)c(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P20 compound treatment 932918.0 354000.0 0.5 917991.0 310000.0 0.43 0.661 0.9971 2070372 Maybridge1_001582 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P21 compound treatment 923204.0 344000.0 0.49 903061.0 295000.0 0.41 0.6365 0.9962 1740892 Maybridge1_001583 CCCc1cc(=O)oc2n(nc(C)c12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P22 compound treatment 932701.0 354000.0 0.5 905415.0 297000.0 0.41 0.6484 0.9954 2070373 Maybridge1_001584 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P23 mock treatment 894014.0 315000.0 0.45 866582.0 258000.0 0.36 0.5712 0.9941 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.545 P24 mock treatment 241054.0 -338000.0 -0.48 295410.0 -313000.0 -0.44 -0.6487 -0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A01 compound treatment 898707.0 283000.0 0.4 830686.0 227000.0 0.32 0.5088 0.9931 2070374 Maybridge1_001585 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A02 compound treatment 834008.0 218000.0 0.31 818990.0 216000.0 0.3 0.4322 0.9999 2070375 Maybridge1_001586 Cc1ccc(OS(=O)(=O)c2ccc(Cl)cc2)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A03 compound treatment 881737.0 266000.0 0.38 842950.0 240000.0 0.33 0.5038 0.9981 2070376 Maybridge1_001587 Nc1ccccc1c2nnc(o2)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A04 compound treatment 880137.0 264000.0 0.38 852384.0 249000.0 0.35 0.5115 0.9992 2070377 Maybridge1_001588 CC(=O)Nc1ccc(cc1Br)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A05 compound treatment 890683.0 275000.0 0.39 879032.0 276000.0 0.38 0.5484 1.0 2070378 Maybridge1_001589 FC(F)(F)C1=NNC(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A06 compound treatment 877713.0 262000.0 0.37 897746.0 295000.0 0.41 0.5538 0.9988 2070379 Maybridge1_001590 CC(C)(C)c1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A07 compound treatment 916144.0 300000.0 0.43 903492.0 300000.0 0.42 0.5982 1.0 1036891 Maybridge1_001591 CC(C)(C)C1=NN(C(=O)C1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A08 compound treatment 911793.0 296000.0 0.42 919811.0 317000.0 0.44 0.6099 0.9997 2070380 Maybridge1_001592 COc1ccc(Br)cc1S(=O)(=O)Oc2c(Cl)cc(cc2Br)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A09 compound treatment 908251.0 292000.0 0.42 937073.0 334000.0 0.47 0.6233 0.9984 2070381 Maybridge1_001593 Clc1ccc(cc1)S(=O)(=O)Oc2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A10 compound treatment 933171.0 317000.0 0.45 912508.0 309000.0 0.43 0.6242 0.9997 2070382 Maybridge1_001594 NC(=O)c1sc2ccccc2c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A11 compound treatment 923019.0 307000.0 0.44 908883.0 306000.0 0.43 0.6104 0.9999 2070383 Maybridge1_001595 C/C(=N\OC(=O)c1ccc(Cl)cc1)/c2ccn(c2)S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A12 compound treatment 956625.0 341000.0 0.48 912439.0 309000.0 0.43 0.6477 0.9983 1169386 Maybridge1_001596 COc1ccc(Br)c(OC)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A13 compound treatment 935738.0 320000.0 0.45 916283.0 313000.0 0.44 0.6305 0.9998 2070384 Maybridge1_001597 [O-][N+](=O)c1ccc(Sc2cc(Cl)ccc2Cl)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A14 compound treatment 943685.0 328000.0 0.47 915068.0 312000.0 0.43 0.6373 0.9994 2070385 Maybridge1_001598 COc1c(Cl)cc([N+](=O)[O-])c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A15 compound treatment 974997.0 359000.0 0.51 936201.0 333000.0 0.46 0.6896 0.9989 2070386 Maybridge1_001599 C/C(=N\OC(=O)c1cc2ccccc2s1)/c3cc[nH]c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A16 compound treatment 933359.0 318000.0 0.45 941771.0 339000.0 0.47 0.6532 0.9998 2070387 Maybridge1_001600 [O-][N+](=O)c1ccc2ncccc2c1n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A17 compound treatment 960346.0 345000.0 0.49 937392.0 334000.0 0.47 0.676 0.9997 1262589 Maybridge1_001601 Cc1cc(Oc2ccc(N)cn2)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A18 compound treatment 929827.0 314000.0 0.45 891513.0 288000.0 0.4 0.6001 0.9986 2070388 Maybridge1_001602 Clc1ccc(cc1)C(=O)CSC(=S)NNc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A19 compound treatment 955054.0 339000.0 0.48 909604.0 306000.0 0.43 0.6433 0.9982 2070389 Maybridge1_001603 C/C(=N\N=C(/N)\SCc1ccc(Cl)cc1Cl)/c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A20 compound treatment 923690.0 308000.0 0.44 906674.0 303000.0 0.42 0.6089 0.9999 2070390 Maybridge1_001604 CCOC(=O)N1CCCN=C1SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A21 compound treatment 928255.0 312000.0 0.44 883107.0 280000.0 0.39 0.5902 0.9979 2070391 Maybridge1_001605 Cc1ccc(OCc2ccc(Cl)c(Cl)c2)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A22 compound treatment 931011.0 315000.0 0.45 842603.0 239000.0 0.33 0.5531 0.9895 2070392 Maybridge1_001606 CN(C)/C=N/c1n[nH]c(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A23 mock treatment 905875.0 290000.0 0.41 826167.0 223000.0 0.31 0.5116 0.9903 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 A24 mock treatment 162525.0 -453000.0 -0.64 149156.0 -454000.0 -0.63 -0.9036 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B01 compound treatment 829131.0 213000.0 0.3 828768.0 226000.0 0.31 0.437 0.9998 2070393 Maybridge1_001607 CN(C)Cc1ccc(CSCCNC(=O)Nc2ccc(Cl)cc2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B02 compound treatment 826795.0 211000.0 0.3 846125.0 243000.0 0.34 0.4517 0.9982 2070394 Maybridge1_001608 O=C(NNc1ccccc1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B03 compound treatment 879055.0 263000.0 0.37 915615.0 312000.0 0.44 0.5728 0.9971 1389651 Maybridge1_001609 O=S(=O)(NCc1cccnc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B04 compound treatment 869422.0 254000.0 0.36 912310.0 309000.0 0.43 0.5599 0.9961 1135267 Maybridge1_001610 COc1ccc(OC)c(CNC(=O)Cc2cccs2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B05 compound treatment 903204.0 287000.0 0.41 904602.0 301000.0 0.42 0.5862 0.9999 2070395 Maybridge1_001611 COc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B06 compound treatment 895830.0 280000.0 0.4 867961.0 265000.0 0.37 0.5427 0.9993 1245092 Maybridge1_001612 COC(=O)CNC(=O)c1cccnc1Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B07 compound treatment 943215.0 327000.0 0.47 951170.0 348000.0 0.49 0.6724 0.9998 1583698 Maybridge1_001613 COc1ccccc1N2CC(C)(C)C(=O)NC2=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B08 compound treatment 925744.0 310000.0 0.44 921047.0 318000.0 0.44 0.6251 1.0 2070396 Maybridge1_001614 CCOC(=O)CNC(=O)c1cccnc1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B09 compound treatment 949925.0 334000.0 0.48 937138.0 334000.0 0.47 0.6653 1.0 2070397 Maybridge1_001615 CCOC(=O)N1CCCN=C1NNc2cc(Cl)ccc2OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B10 compound treatment 913173.0 297000.0 0.42 951956.0 349000.0 0.49 0.643 0.9976 2070398 Maybridge1_001616 CCOC(=O)CNC(=O)c1cc(ccc1Oc2ccc(OC)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B11 compound treatment 923540.0 308000.0 0.44 941753.0 339000.0 0.47 0.6433 0.9993 2070399 Maybridge1_001617 Cc1cc(cc(C)c1OC(=O)Nc2ccc(OC(F)(F)F)cc2)c3nn(C)c(=O)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B12 compound treatment 936184.0 320000.0 0.46 938503.0 335000.0 0.47 0.6528 0.9999 2070400 Maybridge1_001618 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=N)c(C#N)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B13 compound treatment 964739.0 349000.0 0.5 954686.0 351000.0 0.49 0.6975 1.0 2070401 Maybridge1_001619 COc1ccc(Oc2ccc(NC(=O)Nc3ccc(SC(F)(F)F)cc3)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B14 compound treatment 929372.0 314000.0 0.45 906750.0 304000.0 0.42 0.6147 0.9997 2070402 Maybridge1_001620 Clc1cccc(c1)C(=O)OCCSc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B15 compound treatment 950532.0 335000.0 0.48 995617.0 392000.0 0.55 0.7236 0.9976 2070403 Maybridge1_001621 Cc1ccc(SCC(=O)Nc2ccc(F)c(F)c2F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B16 compound treatment 930186.0 314000.0 0.45 975962.0 373000.0 0.52 0.6837 0.9972 2070404 Maybridge1_001622 Cc1n[nH]c(=O)c2noc(/C=C/c3ccsc3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B17 compound treatment 959905.0 344000.0 0.49 947082.0 344000.0 0.48 0.6851 0.9999 2070405 Maybridge1_001623 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B18 compound treatment 917085.0 301000.0 0.43 951028.0 348000.0 0.49 0.646 0.9981 2070406 Maybridge1_001624 COc1cc(OC)c([N+](=O)[O-])c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B19 compound treatment 913095.0 297000.0 0.42 987480.0 384000.0 0.54 0.6779 0.9931 2070407 Maybridge1_001625 COC(=O)c1ccc(Cl)cc1N(CCCC#N)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B20 compound treatment 877250.0 261000.0 0.37 940203.0 337000.0 0.47 0.5952 0.9933 1008366 Maybridge1_001626 [O-][N+](=O)c1ccc(NN=C2CCCCC2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B21 compound treatment 949840.0 334000.0 0.48 946582.0 343000.0 0.48 0.6745 1.0 2070408 Maybridge1_001627 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2NS(=O)(=O)c3ccc(C)cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B22 compound treatment 888805.0 273000.0 0.39 898859.0 296000.0 0.41 0.5661 0.9995 2070409 Maybridge1_001628 Cn1nc(O)cc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B23 mock treatment 928692.0 313000.0 0.44 894652.0 291000.0 0.41 0.6021 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 B24 mock treatment 171599.0 -444000.0 -0.63 136709.0 -466000.0 -0.65 -0.9067 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C01 compound treatment 814899.0 199000.0 0.28 773685.0 170000.0 0.24 0.3683 0.9962 2070410 Maybridge1_001629 [O-][N+](=O)c1ccccc1c2nnc(o2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C02 compound treatment 792012.0 176000.0 0.25 807187.0 204000.0 0.28 0.3784 0.998 1438164 Maybridge1_001630 COc1ccc(COc2ccc(CC#N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C03 compound treatment 876112.0 260000.0 0.37 864658.0 261000.0 0.36 0.5196 1.0 1286595 Maybridge1_001631 OC(=O)CCC(=O)Nc1ccccc1c2nnc(o2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C04 compound treatment 854927.0 239000.0 0.34 853688.0 250000.0 0.35 0.4875 0.9999 2070411 Maybridge1_001632 Clc1cncc(OS(=O)(=O)c2cc(Cl)cc(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C05 compound treatment 878271.0 262000.0 0.37 882978.0 280000.0 0.39 0.5398 0.9998 2070412 Maybridge1_001633 Fc1ccc(cc1F)c2cn(c3ccccc3)c(=Nc4ccccc4)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C06 compound treatment 859700.0 244000.0 0.35 805343.0 202000.0 0.28 0.4446 0.9947 2070413 Maybridge1_001634 CC(C)(C)c1ccc(Oc2ccc(cn2)[N+](=O)[O-])c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C07 compound treatment 905891.0 290000.0 0.41 929612.0 326000.0 0.46 0.6136 0.9988 1503866 Maybridge1_001635 Cc1onc(c1C(=O)Oc2ccc(CC#N)cc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C08 compound treatment 894378.0 279000.0 0.4 886048.0 283000.0 0.39 0.5591 1.0 2070414 Maybridge1_001636 CC(C)(C)c1cc(Cl)c(OS(=O)(=O)c2cc(Cl)cc(Cl)c2)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C09 compound treatment 897205.0 281000.0 0.4 915268.0 312000.0 0.44 0.5907 0.9991 2070415 Maybridge1_001637 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C10 compound treatment 882471.0 267000.0 0.38 909005.0 306000.0 0.43 0.5697 0.9983 2070416 Maybridge1_001638 [O-][N+](=O)c1cccnc1NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C11 compound treatment 933305.0 317000.0 0.45 950766.0 348000.0 0.48 0.662 0.9994 2070417 Maybridge1_001639 C/C(=N\OC(=O)c1ccc(cc1)C(F)(F)F)/c2ccn(c2)S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C12 compound treatment 866917.0 251000.0 0.36 921073.0 318000.0 0.44 0.566 0.9942 1478654 Maybridge1_001640 COc1ccc(Br)c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C13 compound treatment 897254.0 281000.0 0.4 962337.0 359000.0 0.5 0.6372 0.9938 2070418 Maybridge1_001641 CC(=O)c1cccn1S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C14 compound treatment 903822.0 288000.0 0.41 937838.0 335000.0 0.47 0.6196 0.9979 2070419 Maybridge1_001642 Nc1nnc(SCC#N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C15 compound treatment 937255.0 321000.0 0.46 970791.0 368000.0 0.51 0.6858 0.9984 1565189 Maybridge1_001643 CC(C)Oc1ccccc1Oc2ccc(N)cn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C16 compound treatment 876764.0 261000.0 0.37 942764.0 340000.0 0.47 0.5973 0.9927 2070420 Maybridge1_001644 CCOC(=O)CC(=O)CSc1nnc(NC(=O)c2c(F)cccc2F)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C17 compound treatment 896863.0 281000.0 0.4 938030.0 335000.0 0.47 0.6128 0.997 1225421 Maybridge1_001645 CC(C)c1cc(Oc2ccc(N)cn2)cc(c1)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C18 compound treatment 877465.0 262000.0 0.37 901148.0 298000.0 0.42 0.5569 0.9985 2070421 Maybridge1_001646 [O-][N+](=O)c1cccc(c1)c2csc(=S)n2N(C(=O)c3ccc(cc3)C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C19 compound treatment 877627.0 262000.0 0.37 962394.0 359000.0 0.5 0.6175 0.9893 2070422 Maybridge1_001647 CCO/N=C(\C)/c1ccc(C)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C20 compound treatment 866365.0 251000.0 0.36 924017.0 321000.0 0.45 0.5683 0.9936 2070423 Maybridge1_001648 Cn1cc(C(=O)Nc2ccc(F)c(F)c2F)c(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C21 compound treatment 886139.0 270000.0 0.38 931127.0 328000.0 0.46 0.5952 0.9963 1781058 Maybridge1_001649 Cc1cccc(NC(=O)c2ccc(Cl)cc2[N+](=O)[O-])n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C22 compound treatment 851505.0 236000.0 0.34 897446.0 294000.0 0.41 0.5272 0.9949 2070424 Maybridge1_001650 [O-][N+](=O)c1cccnc1Oc2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C23 mock treatment 907142.0 291000.0 0.41 877721.0 275000.0 0.38 0.5637 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 C24 mock treatment 156291.0 -460000.0 -0.65 160629.0 -443000.0 -0.62 -0.8985 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D01 compound treatment 866745.0 251000.0 0.36 859143.0 256000.0 0.36 0.5047 1.0 2070425 Maybridge1_001651 Nc1cccnc1Oc2ccccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D02 compound treatment 861626.0 246000.0 0.35 893576.0 290000.0 0.4 0.5336 0.9973 1679983 Maybridge1_001652 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(C)cc2NS(=O)(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D03 compound treatment 915434.0 300000.0 0.43 949653.0 346000.0 0.48 0.643 0.998 1304103 Maybridge1_001653 Clc1ccc(CNS(=O)(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D04 compound treatment 873971.0 258000.0 0.37 932126.0 329000.0 0.46 0.584 0.9939 2070426 Maybridge1_001654 CN(C)/C=N/c1cc(C)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D05 compound treatment 903957.0 288000.0 0.41 965501.0 362000.0 0.51 0.6471 0.9946 2070427 Maybridge1_001655 [O-][N+](=O)c1ccc(Sc2ccccc2)c(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D06 compound treatment 877728.0 262000.0 0.37 904169.0 301000.0 0.42 0.5602 0.9982 1575755 Maybridge1_001656 COc1ccc(SCC(=O)O)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D07 compound treatment 936619.0 321000.0 0.46 1014594.0 411000.0 0.57 0.7283 0.9935 1662175 Maybridge1_001657 COc1ccc(cc1)n2c(=S)[nH]c(=O)c3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D08 compound treatment 914757.0 299000.0 0.43 950635.0 347000.0 0.48 0.6433 0.9979 1709190 Maybridge1_001658 Cc1ccc(cc1)S(=O)(=O)N(CC=C)c2ccccc2C(=O)NCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D09 compound treatment 936473.0 321000.0 0.46 938148.0 335000.0 0.47 0.6528 0.9999 2070428 Maybridge1_001659 COc1ccccc1N2CC(C)(C)C(=O)N=C2Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D10 compound treatment 936428.0 321000.0 0.46 1007783.0 405000.0 0.56 0.7214 0.9944 2070429 Maybridge1_001660 COc1ccc(Oc2ccc(cc2C(=O)NCC(=O)O)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D11 compound treatment 942874.0 327000.0 0.47 1001502.0 398000.0 0.56 0.7217 0.9961 2070430 Maybridge1_001661 Nc1nnc(Sc2cc3C(=O)NC(=O)c3cc2[N+](=O)[O-])s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D12 compound treatment 888838.0 273000.0 0.39 900912.0 298000.0 0.42 0.5682 0.9994 2070431 Maybridge1_001662 CC(C)(C)OC(=O)C(C)(C)Sc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D13 compound treatment 944738.0 329000.0 0.47 1022034.0 419000.0 0.58 0.7438 0.9939 2070432 Maybridge1_001663 Cc1ccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D14 compound treatment 927007.0 311000.0 0.44 991751.0 389000.0 0.54 0.6961 0.9949 1038633 Maybridge1_001664 Cc1ccc(cc1)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D15 compound treatment 996078.0 380000.0 0.54 1071875.0 469000.0 0.65 0.8446 0.9956 2070433 Maybridge1_001665 Fc1ccc(NC(=O)CSc2ccccc2)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D16 compound treatment 951525.0 336000.0 0.48 1040156.0 437000.0 0.61 0.7685 0.9927 1513571 Maybridge1_001666 Cc1nn(C)c(=O)c(N)c1c2cc([nH]n2)c3ccsc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D17 compound treatment 972610.0 357000.0 0.51 992933.0 390000.0 0.54 0.7431 0.9994 2070434 Maybridge1_001667 S=c1nc2sccn2c3ncccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D18 compound treatment 931630.0 316000.0 0.45 980103.0 377000.0 0.53 0.6893 0.9969 1025893 Maybridge1_001668 [O-][N+](=O)c1cccc(c1)C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D19 compound treatment 956937.0 341000.0 0.49 1006386.0 403000.0 0.56 0.7406 0.9973 2070435 Maybridge1_001669 [O-][N+](=O)c1ccc(cc1)N2N=C(CCC2=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D20 compound treatment 935911.0 320000.0 0.46 988715.0 386000.0 0.54 0.7021 0.9966 1500830 Maybridge1_001670 CC(C)(Oc1ccc(cc1)C(=O)N)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D21 compound treatment 943696.0 328000.0 0.47 1007112.0 404000.0 0.56 0.728 0.9956 2070436 Maybridge1_001671 OC1=C(CCN(c2ccccc12)S(=O)(=O)c3ccc(Cl)cc3)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D22 compound treatment 915918.0 300000.0 0.43 909012.0 306000.0 0.43 0.6034 1.0 2070437 Maybridge1_001672 Nc1ccc(Oc2cc(ccc2Cl)C(F)(F)F)cc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D23 mock treatment 1001148.0 385000.0 0.55 958448.0 355000.0 0.5 0.7378 0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 D24 mock treatment 158355.0 -457000.0 -0.65 134708.0 -468000.0 -0.65 -0.922 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E01 compound treatment 847091.0 231000.0 0.33 872817.0 270000.0 0.38 0.4985 0.9978 2070438 Maybridge1_001673 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E02 compound treatment 880980.0 265000.0 0.38 864387.0 261000.0 0.36 0.5242 0.9999 2070439 Maybridge1_001674 [O-][N+](=O)c1ccc(Oc2ccc(CC#N)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E03 compound treatment 927416.0 312000.0 0.44 995370.0 392000.0 0.55 0.7001 0.9945 2070440 Maybridge1_001675 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NC(=O)NC(=O)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E04 compound treatment 921486.0 306000.0 0.43 971740.0 369000.0 0.51 0.6708 0.9965 1006390 Maybridge1_001676 S=C(Nc1ccccc1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E05 compound treatment 934689.0 319000.0 0.45 1021699.0 419000.0 0.58 0.7334 0.9922 2070441 Maybridge1_001677 Fc1ccc(cc1F)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E06 compound treatment 929586.0 314000.0 0.45 918427.0 315000.0 0.44 0.6264 1.0 2070442 Maybridge1_001678 COc1ccc([N+](=O)[O-])c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E07 compound treatment 954327.0 339000.0 0.48 1036984.0 434000.0 0.61 0.7682 0.9936 2070443 Maybridge1_001679 Cc1onc(c1C(=O)Nc2ccc(F)c(Cl)c2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E08 compound treatment 954121.0 338000.0 0.48 1017908.0 415000.0 0.58 0.7492 0.9958 1110266 Maybridge1_001680 CNc1ccccc1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E09 compound treatment 965569.0 350000.0 0.5 992239.0 389000.0 0.54 0.7354 0.9991 2070444 Maybridge1_001681 Clc1cc(Cl)cc(c1)S(=O)(=O)Oc2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E10 compound treatment 940221.0 324000.0 0.46 991770.0 389000.0 0.54 0.7094 0.9968 2070445 Maybridge1_001682 [O-][N+](=O)c1cccnc1NCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E11 compound treatment 969466.0 354000.0 0.5 1071375.0 468000.0 0.65 0.8173 0.9917 2070446 Maybridge1_001683 C/C(=N\O)/c1ccn(c1)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E12 compound treatment 918087.0 302000.0 0.43 1037042.0 434000.0 0.61 0.7318 0.986 1178220 Maybridge1_001684 COc1ccc(Cl)c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E13 compound treatment 951468.0 336000.0 0.48 1075072.0 472000.0 0.66 0.8029 0.9876 2070447 Maybridge1_001685 Nc1ccc(Sc2cc(Cl)ccc2Cl)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E14 compound treatment 933630.0 318000.0 0.45 1011437.0 408000.0 0.57 0.7222 0.9935 1323451 Maybridge1_001686 COc1c(Cl)cc(Br)c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E15 compound treatment 982777.0 367000.0 0.52 1069357.0 466000.0 0.65 0.8287 0.9941 2070448 Maybridge1_001687 C/C(=N\O)/c1ccc(C)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E16 compound treatment 943086.0 327000.0 0.47 1031854.0 429000.0 0.6 0.7518 0.9923 2070449 Maybridge1_001688 COC(=O)c1c(OC)ccc(N/C=N/O)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E17 compound treatment 941697.0 326000.0 0.46 1096884.0 494000.0 0.69 0.8146 0.9814 2070450 Maybridge1_001689 COc1ccc(Oc2ccc(N)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E18 compound treatment 940807.0 325000.0 0.46 984540.0 381000.0 0.53 0.7029 0.9976 2070451 Maybridge1_001690 CCOC(CN(c1ccc(F)cc1)S(=O)(=O)c2cc(Cl)cc(Cl)c2)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E19 compound treatment 967505.0 352000.0 0.5 1066523.0 463000.0 0.65 0.8106 0.992 2070452 Maybridge1_001691 OCCNc1ccc(NCCO)nn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E20 compound treatment 931641.0 316000.0 0.45 1030554.0 427000.0 0.6 0.739 0.9903 1098980 Maybridge1_001692 COC(=O)c1ccncc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E21 compound treatment 970616.0 355000.0 0.5 1061669.0 458000.0 0.64 0.8089 0.9931 1078393 Maybridge1_001693 Nc1ncc(Br)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E22 compound treatment 977525.0 362000.0 0.51 1005695.0 402000.0 0.56 0.7607 0.999 2070453 Maybridge1_001694 [O-][N+](=O)c1cccnc1Oc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E23 mock treatment 1020179.0 404000.0 0.58 996376.0 393000.0 0.55 0.7944 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 E24 mock treatment 173003.0 -443000.0 -0.63 154667.0 -449000.0 -0.63 -0.8876 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F01 compound treatment 883842.0 268000.0 0.38 849954.0 247000.0 0.34 0.5129 0.9987 2070454 Maybridge1_001695 OC(=O)CSc1ccc(cn1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F02 compound treatment 906997.0 291000.0 0.41 896371.0 293000.0 0.41 0.5819 1.0 2070455 Maybridge1_001696 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2cc(cc(c2)C(C)(C)C)C(=O)NNC(=O)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F03 compound treatment 908405.0 293000.0 0.42 964508.0 361000.0 0.5 0.6505 0.9955 2070456 Maybridge1_001697 CS(=O)(=O)NCc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F04 compound treatment 906071.0 290000.0 0.41 951103.0 348000.0 0.49 0.635 0.9968 1918990 Maybridge1_001698 c1csc(c1)c2cnc3ccccc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F05 compound treatment 975332.0 360000.0 0.51 980304.0 377000.0 0.53 0.7334 0.9999 2070457 Maybridge1_001699 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)c(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F06 compound treatment 937446.0 322000.0 0.46 985989.0 383000.0 0.53 0.7009 0.997 1570677 Maybridge1_001700 OC(=O)c1cccnc1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F07 compound treatment 954242.0 338000.0 0.48 1030663.0 427000.0 0.6 0.7619 0.9944 1524701 Maybridge1_001701 Brc1ccc(cc1)n2c(=S)[nH]c(=O)c3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F08 compound treatment 966304.0 350000.0 0.5 1004481.0 401000.0 0.56 0.7482 0.9983 1346644 Maybridge1_001702 Cc1ccc(Sc2ncccc2C(=O)NCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F09 compound treatment 1035249.0 419000.0 0.6 1055621.0 452000.0 0.63 0.868 0.9996 2070458 Maybridge1_001703 COc1ccccc1N2CC(C)(C)C(=O)N(C(=O)c3c(F)cccc3Cl)C2=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F10 compound treatment 964238.0 348000.0 0.5 999015.0 396000.0 0.55 0.7407 0.9985 2070459 Maybridge1_001704 Cc1c(Cl)cccc1SCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F11 compound treatment 959829.0 344000.0 0.49 1071934.0 469000.0 0.65 0.8082 0.9898 1538792 Maybridge1_001705 Nc1cc2C(=O)NC(=O)c2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F12 compound treatment 933028.0 317000.0 0.45 955479.0 352000.0 0.49 0.6664 0.9991 2070460 Maybridge1_001706 CC(C)(C)OC(=O)C(C)(C)Sc1ccc(cn1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F13 compound treatment 940433.0 325000.0 0.46 1069346.0 466000.0 0.65 0.7861 0.9859 2070461 Maybridge1_001707 COc1ccc(Oc2ccc(cc2C(=O)O)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F14 compound treatment 978088.0 362000.0 0.52 1042728.0 440000.0 0.61 0.7978 0.9963 1013662 Maybridge1_001708 Cc1ccc(cc1)S(=O)(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F15 compound treatment 975933.0 360000.0 0.51 1033954.0 431000.0 0.6 0.7869 0.9968 2070462 Maybridge1_001709 Fc1ccc(NC(=O)CSc2ssc(=S)c2c3ccccc3)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F16 compound treatment 954753.0 339000.0 0.48 1010124.0 407000.0 0.57 0.7421 0.9967 2070463 Maybridge1_001710 CC(C)(C(=O)Oc1ccc(Cl)cc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F17 compound treatment 987773.0 372000.0 0.53 1055610.0 452000.0 0.63 0.8202 0.9962 2070464 Maybridge1_001711 O/N=C/C(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F18 compound treatment 925772.0 310000.0 0.44 1030092.0 427000.0 0.6 0.7327 0.9891 2070465 Maybridge1_001712 COC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F19 compound treatment 986875.0 371000.0 0.53 1074056.0 471000.0 0.66 0.8375 0.9941 2070466 Maybridge1_001713 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1SCC(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F20 compound treatment 981879.0 366000.0 0.52 1045664.0 442000.0 0.62 0.8045 0.9964 2070467 Maybridge1_001714 COc1ccc(N)c(Sc2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F21 compound treatment 979756.0 364000.0 0.52 1044036.0 441000.0 0.61 0.8007 0.9963 1048764 Maybridge1_001715 CCOC(=O)c1cnn(c1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F22 compound treatment 975914.0 360000.0 0.51 989991.0 387000.0 0.54 0.7436 0.9997 1408448 Maybridge1_001716 Cc1nc(cs1)c2cc(C#N)c(=O)[nH]c2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F23 mock treatment 1038780.0 423000.0 0.6 997189.0 394000.0 0.55 0.8139 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 F24 mock treatment 147134.0 -469000.0 -0.67 160011.0 -443000.0 -0.62 -0.9084 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G01 compound treatment 831502.0 216000.0 0.31 856778.0 254000.0 0.35 0.467 0.9975 2070468 Maybridge1_001717 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)NC(=O)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G02 compound treatment 831444.0 216000.0 0.31 871195.0 268000.0 0.37 0.4811 0.9952 1111505 Maybridge1_001718 CC(=O)Nc1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G03 compound treatment 908286.0 292000.0 0.42 956350.0 353000.0 0.49 0.6424 0.9965 2070469 Maybridge1_001719 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G04 compound treatment 857830.0 242000.0 0.34 939125.0 336000.0 0.47 0.5747 0.9885 2070470 Maybridge1_001720 [O-][N+](=O)c1cccnc1Oc2cncc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G05 compound treatment 909021.0 293000.0 0.42 998768.0 396000.0 0.55 0.685 0.9905 1029371 Maybridge1_001721 OC(=O)CCC(N1C(=O)c2ccccc2C1=O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G06 compound treatment 880731.0 265000.0 0.38 863235.0 260000.0 0.36 0.5228 0.9998 2070471 Maybridge1_001722 CC(C)(C)c1ccc(Oc2ncccc2[N+](=O)[O-])c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G07 compound treatment 936882.0 321000.0 0.46 996396.0 393000.0 0.55 0.7106 0.9959 2070472 Maybridge1_001723 Cc1onc(c1C(=O)Nc2cccc(Cl)c2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G08 compound treatment 901333.0 286000.0 0.41 930993.0 328000.0 0.46 0.6104 0.9982 2070473 Maybridge1_001724 CCOC(=O)CC(=O)CSc1nnc(N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G09 compound treatment 934942.0 319000.0 0.45 971700.0 369000.0 0.51 0.6843 0.9981 1396369 Maybridge1_001725 CN(c1c2CCCCc2nn1C)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G10 compound treatment 921495.0 306000.0 0.43 990103.0 387000.0 0.54 0.689 0.9943 2070474 Maybridge1_001726 [O-][N+](=O)c1cccnc1NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G11 compound treatment 883163.0 267000.0 0.38 966729.0 364000.0 0.51 0.6274 0.9899 1274708 Maybridge1_001727 COc1cccc(OC)c1C(=O)NC(=O)Oc2c(F)cccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G12 compound treatment 870229.0 254000.0 0.36 962825.0 360000.0 0.5 0.6105 0.9871 2070475 Maybridge1_001728 Cc1ccc(cc1)n2ncc(C#N)c2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G13 compound treatment 928603.0 313000.0 0.44 1016957.0 414000.0 0.58 0.7226 0.9917 1070439 Maybridge1_001729 [O-][N+](=O)c1ccc(Oc2cccc(c2)C(F)(F)F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G14 compound treatment 963190.0 347000.0 0.49 1044974.0 442000.0 0.62 0.785 0.994 2070476 Maybridge1_001730 Nc1c(C#N)cnn1c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G15 compound treatment 975469.0 360000.0 0.51 1061925.0 459000.0 0.64 0.8141 0.9938 1575604 Maybridge1_001731 Cc1cc(Cl)ccc1Oc2ccc(N)cn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G16 compound treatment 945672.0 330000.0 0.47 1013061.0 410000.0 0.57 0.7359 0.9952 2070477 Maybridge1_001732 Oc1c(cnn(c2ccccc2)c1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G17 compound treatment 1102872.0 487000.0 0.69 1252283.0 649000.0 0.91 1.1299 0.9913 1065659 Maybridge1_001733 Nc1ccc(Oc2ccc(F)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G18 compound treatment 901553.0 286000.0 0.41 949569.0 346000.0 0.48 0.6289 0.9963 2070478 Maybridge1_001734 CCOC(CN(c1ccc(F)cc1)S(=O)(=O)c2ccc(F)cc2F)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G19 compound treatment 959019.0 343000.0 0.49 1012645.0 409000.0 0.57 0.7489 0.9969 2070479 Maybridge1_001735 Cc1ccc(Oc2ccc(cn2)[N+](=O)[O-])c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G20 compound treatment 852422.0 237000.0 0.34 1007426.0 404000.0 0.56 0.6366 0.9696 1049801 Maybridge1_001736 NC(=O)c1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G21 compound treatment 922137.0 306000.0 0.44 1017350.0 414000.0 0.58 0.7165 0.9903 1725682 Maybridge1_001737 CC(=O)Nc1ncccc1OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G22 compound treatment 946228.0 330000.0 0.47 966032.0 363000.0 0.51 0.6901 0.9993 2070480 Maybridge1_001738 Nc1cccnc1Oc2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G23 mock treatment 957271.0 341000.0 0.49 973581.0 370000.0 0.52 0.7086 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 G24 mock treatment 146914.0 -469000.0 -0.67 167167.0 -436000.0 -0.61 -0.9015 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H01 compound treatment 850658.0 235000.0 0.33 826802.0 224000.0 0.31 0.4567 0.9994 2070481 Maybridge1_001739 COC(=O)CS(=O)(=O)c1ccc(cn1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H02 compound treatment 869626.0 254000.0 0.36 881824.0 279000.0 0.39 0.53 0.9993 2070482 Maybridge1_001740 CC(C)(C)c1cc(cc(c1)C(=O)NNC(=O)c2ccc(Cl)cc2Cl)C(=O)NNC(=O)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H03 compound treatment 872029.0 256000.0 0.36 950476.0 347000.0 0.48 0.6001 0.9902 1025749 Maybridge1_001741 CS(=O)(=O)NCc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H04 compound treatment 899043.0 283000.0 0.4 924036.0 321000.0 0.45 0.6012 0.9986 2070483 Maybridge1_001742 COC(=O)CNC(=O)c1cc(ccc1Oc2ccc(OC)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H05 compound treatment 918139.0 302000.0 0.43 952897.0 350000.0 0.49 0.6489 0.998 2070484 Maybridge1_001743 [O-][N+](=O)c1ccc(SCc2ccccc2)c(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H06 compound treatment 911475.0 296000.0 0.42 939024.0 336000.0 0.47 0.6285 0.9985 2070485 Maybridge1_001744 OC(=O)c1cccnc1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H07 compound treatment 926554.0 311000.0 0.44 1022199.0 419000.0 0.58 0.7257 0.9905 1297323 Maybridge1_001745 CSc1nc(=O)c2cccnc2n1c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H08 compound treatment 932206.0 316000.0 0.45 981518.0 378000.0 0.53 0.6913 0.9969 1641310 Maybridge1_001746 NC(=O)c1cccnc1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H09 compound treatment 935457.0 320000.0 0.45 983910.0 381000.0 0.53 0.6969 0.997 1733777 Maybridge1_001747 COC(=O)c1ccccc1C(=O)c2cc(C)c(O)c(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H10 compound treatment 934633.0 319000.0 0.45 960530.0 357000.0 0.5 0.673 0.9989 2070486 Maybridge1_001748 OC(=O)CSc1cccc2cccc(Cl)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H11 compound treatment 970237.0 354000.0 0.5 984943.0 382000.0 0.53 0.7329 0.9996 2070487 Maybridge1_001749 CCCCNC(=O)Nc1nnc(s1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H12 compound treatment 886113.0 270000.0 0.38 953809.0 351000.0 0.49 0.6176 0.9929 2070488 Maybridge1_001750 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H13 compound treatment 943519.0 328000.0 0.47 1013464.0 410000.0 0.57 0.7341 0.9948 2070489 Maybridge1_001751 Cc1nc2ccccn2c(=O)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H14 compound treatment 948813.0 333000.0 0.47 989656.0 386000.0 0.54 0.716 0.9979 1038637 Maybridge1_001752 Cc1ccc(cc1)S(=O)(=O)N2CCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H15 compound treatment 976526.0 361000.0 0.51 1048993.0 446000.0 0.62 0.8024 0.9954 2070490 Maybridge1_001753 [O-][N+](=O)c1cc(ccc1Oc2ccc(SC(F)(F)F)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H16 compound treatment 931145.0 315000.0 0.45 977237.0 374000.0 0.52 0.686 0.9972 1597019 Maybridge1_001754 Cc1onc2c(=O)n(nc(c3ccccc3)c12)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H17 compound treatment 946590.0 331000.0 0.47 1034905.0 432000.0 0.6 0.7584 0.9925 2070491 Maybridge1_001755 Cn1ccnc1SCC(=O)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H18 compound treatment 920143.0 304000.0 0.43 991730.0 389000.0 0.54 0.6892 0.9938 1060482 Maybridge1_001756 N#Cc1ccc(cc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H19 compound treatment 977138.0 361000.0 0.51 1004974.0 402000.0 0.56 0.7596 0.9991 2070492 Maybridge1_001757 COC(=O)c1ccc(Cl)cc1N(CCCC#N)S(=O)(=O)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H20 compound treatment 900585.0 285000.0 0.4 966226.0 363000.0 0.51 0.6444 0.9939 2070493 Maybridge1_001758 COc1cc(OC)c([N+](=O)[O-])c(OC)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H21 compound treatment 970733.0 355000.0 0.5 982507.0 379000.0 0.53 0.731 0.9997 2070494 Maybridge1_001759 CCOC(=O)c1cnn(c1C)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H22 compound treatment 949346.0 334000.0 0.47 973730.0 371000.0 0.52 0.7008 0.9991 1644615 Maybridge1_001760 COc1nc(C)c(cc1C#N)c2csc(C)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H23 mock treatment 1001669.0 386000.0 0.55 964412.0 361000.0 0.5 0.7442 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 H24 mock treatment 144452.0 -471000.0 -0.67 160116.0 -443000.0 -0.62 -0.911 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I01 compound treatment 866007.0 250000.0 0.36 855042.0 252000.0 0.35 0.5 1.0 2070495 Maybridge1_001761 COc1ccc(cc1OC)S(=O)(=O)Nc2ccccc2c3nnc(o3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I02 compound treatment 858508.0 243000.0 0.35 875731.0 273000.0 0.38 0.5128 0.9988 2070496 Maybridge1_001762 CC(C)(C)c1cc(OC(=O)c2ccc(Cl)cc2)c(cc1OC(=O)c3ccc(Cl)cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I03 compound treatment 918708.0 303000.0 0.43 982598.0 379000.0 0.53 0.6787 0.9948 1257183 Maybridge1_001763 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(C)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I04 compound treatment 914098.0 298000.0 0.42 966264.0 363000.0 0.51 0.658 0.9961 2070497 Maybridge1_001764 [O-][N+](=O)c1ccc(Oc2cncc(Cl)c2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I05 compound treatment 922463.0 307000.0 0.44 980661.0 377000.0 0.53 0.6806 0.9956 1460964 Maybridge1_001765 Cc1ccc(COc2ccc(CC#N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I06 compound treatment 889477.0 274000.0 0.39 971075.0 368000.0 0.51 0.638 0.9907 2070498 Maybridge1_001766 CN(C)/C=N/c1c(C#N)cnn1c2ccc(F)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I07 compound treatment 923920.0 308000.0 0.44 1023010.0 420000.0 0.59 0.7238 0.9898 2070499 Maybridge1_001767 Clc1ccc(cc1)C(=O)NC(=O)Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I08 compound treatment 910950.0 295000.0 0.42 1019145.0 416000.0 0.58 0.707 0.9874 2070500 Maybridge1_001768 CCCn1c(SC)nnc1SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I09 compound treatment 980712.0 365000.0 0.52 1025965.0 423000.0 0.59 0.7839 0.998 1949637 Maybridge1_001769 Clc1ccc(cc1)S(=O)(=O)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I10 compound treatment 895408.0 280000.0 0.4 983679.0 380000.0 0.53 0.6564 0.9899 2070501 Maybridge1_001770 Nc1cc(Cl)c(cc1Cl)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I11 compound treatment 933568.0 318000.0 0.45 1038366.0 435000.0 0.61 0.7487 0.9894 2070502 Maybridge1_001771 [O-][N+](=O)c1cc(ccc1Oc2ccc(Cl)cc2C3CCCCC3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I12 compound treatment 908184.0 292000.0 0.42 995739.0 393000.0 0.55 0.6811 0.9908 1210951 Maybridge1_001772 COc1c(Cl)cc(Cl)c(OC)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I13 compound treatment 944027.0 328000.0 0.47 1013591.0 410000.0 0.57 0.7348 0.9949 2070503 Maybridge1_001773 [O-][N+](=O)c1ccc(Oc2ccc(F)cc2F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I14 compound treatment 956625.0 341000.0 0.48 1056142.0 453000.0 0.63 0.7894 0.9914 2070504 Maybridge1_001774 N#CCSc1nnc(s1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I15 compound treatment 978564.0 363000.0 0.52 1073936.0 471000.0 0.66 0.829 0.9929 2070505 Maybridge1_001775 [O-][N+](=O)c1ccc(Oc2cccnc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I16 compound treatment 898833.0 283000.0 0.4 999553.0 396000.0 0.55 0.6755 0.9878 2070506 Maybridge1_001776 COC(=O)C1=NN(C(=O)C1)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I17 compound treatment 978078.0 362000.0 0.52 1078627.0 475000.0 0.66 0.8332 0.9922 1562566 Maybridge1_001777 Cc1cccc(Oc2ccc(N)cn2)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I18 compound treatment 933964.0 318000.0 0.45 993854.0 391000.0 0.54 0.7052 0.9957 2070507 Maybridge1_001778 CCOC(CN(C(=O)c1ccc(F)cc1)c2ccc(F)cc2)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I19 compound treatment 949737.0 334000.0 0.47 1031313.0 428000.0 0.6 0.758 0.9936 2070508 Maybridge1_001779 Cc1ccc(Oc2ncccc2[N+](=O)[O-])c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I20 compound treatment 931145.0 315000.0 0.45 1038446.0 435000.0 0.61 0.7463 0.9889 1002904 Maybridge1_001780 OC(=O)c1nccnc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I21 compound treatment 971808.0 356000.0 0.51 1043540.0 440000.0 0.61 0.7922 0.9954 2070509 Maybridge1_001781 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(C)nc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I22 compound treatment 958687.0 343000.0 0.49 1052652.0 449000.0 0.63 0.788 0.9923 2070510 Maybridge1_001782 Nc1ccc(Oc2ccccc2F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I23 mock treatment 995287.0 379000.0 0.54 1013495.0 410000.0 0.57 0.7862 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 I24 mock treatment 163877.0 -452000.0 -0.64 168099.0 -435000.0 -0.61 -0.8835 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J01 compound treatment 868828.0 253000.0 0.36 819936.0 217000.0 0.3 0.4682 0.9962 2070511 Maybridge1_001783 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC(=O)NNC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J02 compound treatment 878056.0 262000.0 0.37 893700.0 291000.0 0.41 0.5502 0.9991 2070512 Maybridge1_001784 CC(C)(C)c1cc(cc(c1)C(=O)NNC(=O)c2ccc(cc2)C(F)(F)F)C(=O)NNC(=O)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J03 compound treatment 943022.0 327000.0 0.47 951403.0 348000.0 0.49 0.6724 0.9998 2070513 Maybridge1_001785 COc1ccc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(Cl)c3)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J04 compound treatment 869814.0 254000.0 0.36 896912.0 294000.0 0.41 0.5451 0.998 1139373 Maybridge1_001786 OC(=O)c1cccnc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J05 compound treatment 932071.0 316000.0 0.45 958229.0 355000.0 0.5 0.6682 0.9988 2070514 Maybridge1_001787 CC/1=NN(C(=O)\C1=C\c2ccc(OCc3ccccc3)cc2)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J06 compound treatment 917877.0 302000.0 0.43 897621.0 294000.0 0.41 0.5941 0.9997 1243528 Maybridge1_001788 COC(=O)CNC(=O)c1cccnc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J07 compound treatment 986099.0 370000.0 0.53 978891.0 376000.0 0.52 0.7429 1.0 1168374 Maybridge1_001789 Brc1ccc(cc1)n2c(SCC#C)nc(=O)c3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J08 compound treatment 933612.0 318000.0 0.45 962222.0 359000.0 0.5 0.6736 0.9987 1458502 Maybridge1_001790 Cc1ccc(Oc2ncccc2C(=O)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J09 compound treatment 960575.0 345000.0 0.49 990743.0 388000.0 0.54 0.7289 0.9988 2070515 Maybridge1_001791 Cc1cc(cc(C)c1OC(=O)c2ccc(cc2)C(F)(F)F)c3nn(C)c(=O)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J10 compound treatment 876040.0 260000.0 0.37 908937.0 306000.0 0.43 0.5632 0.9975 2070516 Maybridge1_001792 [O-][N+](=O)c1cc(Br)c(Oc2cncc(Cl)c2)cc1Oc3cncc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J11 compound treatment 957326.0 342000.0 0.49 930161.0 327000.0 0.46 0.6659 0.9995 2070517 Maybridge1_001793 COC(=O)COc1ccc(SC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J12 compound treatment 931864.0 316000.0 0.45 956408.0 353000.0 0.49 0.6661 0.999 2070518 Maybridge1_001794 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J13 compound treatment 1017620.0 402000.0 0.57 1006985.0 404000.0 0.56 0.8023 1.0 2070519 Maybridge1_001795 CCOC(=O)c1cnc2nc(SC)nn2c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J14 compound treatment 954130.0 338000.0 0.48 1002260.0 399000.0 0.56 0.7338 0.9974 1386298 Maybridge1_001796 O=C(OCCS(=O)(=O)c1ccccn1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J15 compound treatment 1012669.0 397000.0 0.56 998684.0 395000.0 0.55 0.7891 0.9999 2070520 Maybridge1_001797 Fc1ccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J16 compound treatment 940826.0 325000.0 0.46 955101.0 352000.0 0.49 0.6739 0.9995 2070521 Maybridge1_001798 Cc1nn(C)c(=O)c2noc(/C=C/c3ccc(cc3)C(F)(F)F)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J17 compound treatment 996736.0 381000.0 0.54 1028590.0 425000.0 0.59 0.8026 0.999 2070522 Maybridge1_001799 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J18 compound treatment 937328.0 322000.0 0.46 977556.0 374000.0 0.52 0.6925 0.9978 2070523 Maybridge1_001800 CN(C)/C=N\c1cc(C)nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J19 compound treatment 967883.0 352000.0 0.5 1000785.0 398000.0 0.55 0.7461 0.9987 1098259 Maybridge1_001801 Nc1ncccc1OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J20 compound treatment 961406.0 346000.0 0.49 961416.0 358000.0 0.5 0.7008 1.0 1711015 Maybridge1_001802 Fc1ccc(NC(=O)c2c(F)cccc2NC(=O)c3cccs3)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J21 compound treatment 1002333.0 387000.0 0.55 1025802.0 423000.0 0.59 0.8054 0.9994 2070524 Maybridge1_001803 Nc1nc(Oc2ccc(Cl)cc2)ncc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J22 compound treatment 933188.0 317000.0 0.45 923328.0 320000.0 0.45 0.6349 1.0 1159034 Maybridge1_001804 Cc1nc(cs1)c2cc(C#N)c(Sc3ccccc3)nc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J23 mock treatment 1017554.0 402000.0 0.57 976288.0 373000.0 0.52 0.7719 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 J24 mock treatment 161886.0 -454000.0 -0.65 143373.0 -460000.0 -0.64 -0.9099 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K01 compound treatment 848058.0 232000.0 0.33 856589.0 253000.0 0.35 0.4834 0.9994 2070525 Maybridge1_001805 [O-][N+](=O)c1ccccc1C(=O)NNC(=O)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K02 compound treatment 855398.0 240000.0 0.34 889944.0 287000.0 0.4 0.5237 0.9968 2070526 Maybridge1_001806 CC(C)(C)c1cc(OC(=O)c2ccc(cc2)C(F)(F)F)c(cc1OC(=O)c3ccc(cc3)C(F)(F)F)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K03 compound treatment 903603.0 288000.0 0.41 904719.0 302000.0 0.42 0.5868 0.9999 2070527 Maybridge1_001807 CS/C(=N\S(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F)/N4CCCCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K04 compound treatment 877467.0 262000.0 0.37 967892.0 365000.0 0.51 0.6228 0.9882 2070528 Maybridge1_001808 COc1ccc(Oc2c(O)occ2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K05 compound treatment 912387.0 297000.0 0.42 881599.0 278000.0 0.39 0.5728 0.9991 1589783 Maybridge1_001809 Clc1ccc(COc2ccc(CC#N)cc2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K06 compound treatment 918132.0 302000.0 0.43 896221.0 293000.0 0.41 0.593 0.9997 2070529 Maybridge1_001810 CC1=NN(C(=O)C1CCO)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K07 compound treatment 902487.0 287000.0 0.41 955953.0 353000.0 0.49 0.6362 0.9956 1044477 Maybridge1_001811 OC(=O)c1cc2cc(ccc2oc1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K08 compound treatment 893882.0 278000.0 0.4 941486.0 338000.0 0.47 0.6132 0.9961 2070530 Maybridge1_001812 COC(=O)c1cc2ccccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K09 compound treatment 919363.0 304000.0 0.43 988757.0 386000.0 0.54 0.6855 0.9941 2070531 Maybridge1_001813 COc1cc(CC=C)ccc1Oc2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K10 compound treatment 907031.0 291000.0 0.41 919389.0 316000.0 0.44 0.6047 0.9995 2070532 Maybridge1_001814 CN(C)/C=N/c1cc(Cl)c(cc1Cl)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K11 compound treatment 905713.0 290000.0 0.41 972581.0 369000.0 0.52 0.6558 0.9939 2070533 Maybridge1_001815 Cc1cccc(NC(=O)C(F)(F)F)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K12 compound treatment 887294.0 271000.0 0.39 951806.0 349000.0 0.49 0.6168 0.9935 2070534 Maybridge1_001816 COc1c(Cl)cc([N+](=O)[O-])c(OC)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K13 compound treatment 971465.0 356000.0 0.51 999069.0 396000.0 0.55 0.748 0.999 2070535 Maybridge1_001817 [O-][N+](=O)c1ccc(Oc2ccc(Br)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K14 compound treatment 899914.0 284000.0 0.4 974426.0 371000.0 0.52 0.6518 0.9925 2070536 Maybridge1_001818 FC(F)(F)c1cccc(c1)C(=O)CN2C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K15 compound treatment 918315.0 303000.0 0.43 1026402.0 423000.0 0.59 0.7216 0.9879 2070537 Maybridge1_001819 Nc1ccc(Oc2ccc(F)cc2F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K16 compound treatment 897688.0 282000.0 0.4 944886.0 342000.0 0.48 0.6204 0.9963 1003999 Maybridge1_001820 [O-][N+](=O)c1cccc2cnccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K17 compound treatment 948338.0 333000.0 0.47 955545.0 352000.0 0.49 0.6819 0.9998 1711963 Maybridge1_001821 Nc1ccc(Oc2ccc(Cl)cc2C3CCCCC3)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K18 compound treatment 898675.0 283000.0 0.4 979378.0 376000.0 0.52 0.6554 0.9914 2070538 Maybridge1_001822 CCOC(CN(C(=O)c1ccc(C)cc1)c2ccc(F)cc2)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K19 compound treatment 947900.0 332000.0 0.47 1010230.0 407000.0 0.57 0.7354 0.9958 2070539 Maybridge1_001823 Cc1ccc(OCc2c(Cl)cccc2Cl)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K20 compound treatment 907329.0 292000.0 0.41 993393.0 390000.0 0.54 0.678 0.991 1513140 Maybridge1_001824 COC(=O)c1ccncc1C(=O)Nc2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K21 compound treatment 944683.0 329000.0 0.47 1000455.0 397000.0 0.55 0.7225 0.9964 2070540 Maybridge1_001825 Cc1nn(nc1C(=O)Oc2ccc(C)nc2[N+](=O)[O-])c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K22 compound treatment 937155.0 321000.0 0.46 982447.0 379000.0 0.53 0.6971 0.9973 2070541 Maybridge1_001826 Clc1ccc(cc1)S(=O)(=O)Oc2ccc(/C=C/3\NC(=O)NC3=O)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K23 mock treatment 980950.0 365000.0 0.52 957250.0 354000.0 0.49 0.7163 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 K24 mock treatment 157580.0 -458000.0 -0.65 158858.0 -444000.0 -0.62 -0.899 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L01 compound treatment 861826.0 246000.0 0.35 818733.0 216000.0 0.3 0.4599 0.9971 1323730 Maybridge1_001827 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L02 compound treatment 887817.0 272000.0 0.39 871086.0 268000.0 0.37 0.5377 0.9998 2070542 Maybridge1_001828 CCOC(=O)c1cnn(c1C)c2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L03 compound treatment 917566.0 302000.0 0.43 960249.0 357000.0 0.5 0.6556 0.9973 2070543 Maybridge1_001829 CC/1=NN(C(=O)\C1=C\c2ccc(O)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L04 compound treatment 881648.0 266000.0 0.38 881953.0 279000.0 0.39 0.5422 0.9999 1356933 Maybridge1_001830 Cc1ccc(Sc2ncccc2C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L05 compound treatment 931065.0 315000.0 0.45 922164.0 319000.0 0.44 0.6316 1.0 2070544 Maybridge1_001831 CC/1=NN(C(=O)\C1=C\c2ccc(OCc3ccccc3)cc2)c4cccc(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L06 compound treatment 871604.0 256000.0 0.36 878504.0 275000.0 0.38 0.5287 0.9996 1009523 Maybridge1_001832 Cc1cc(O)n2cnnc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L07 compound treatment 955640.0 340000.0 0.48 947212.0 344000.0 0.48 0.681 1.0 1684089 Maybridge1_001833 COc1ccccc1NC(=S)NCC(C)(C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L08 compound treatment 899009.0 283000.0 0.4 904550.0 301000.0 0.42 0.582 0.9998 1563767 Maybridge1_001834 NC(=O)c1cccnc1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L09 compound treatment 938905.0 323000.0 0.46 933450.0 330000.0 0.46 0.6506 1.0 2070545 Maybridge1_001835 CC(C)(C)c1nnc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L10 compound treatment 888396.0 273000.0 0.39 847320.0 244000.0 0.34 0.5149 0.9979 2070546 Maybridge1_001836 COC(=O)c1c(SC)nc([nH]c1=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L11 compound treatment 962614.0 347000.0 0.49 941495.0 338000.0 0.47 0.6824 0.9998 2070547 Maybridge1_001837 Cc1ccc(Sc2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L12 compound treatment 941909.0 326000.0 0.46 928531.0 325000.0 0.45 0.6488 0.9999 2070548 Maybridge1_001838 Cc1ccc(SCc2cc(=O)[nH]c(=O)[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L13 compound treatment 953206.0 337000.0 0.48 954601.0 351000.0 0.49 0.6858 0.9999 2070549 Maybridge1_001839 CSc1nc2ncc(C(=O)O)c(N)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L14 compound treatment 898222.0 282000.0 0.4 967029.0 364000.0 0.51 0.6428 0.9933 1630711 Maybridge1_001840 Nc1[nH]nc2[nH]c(nc(=O)c12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L15 compound treatment 990033.0 374000.0 0.53 944073.0 341000.0 0.48 0.7125 0.9984 2070550 Maybridge1_001841 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L16 compound treatment 948917.0 333000.0 0.47 975676.0 372000.0 0.52 0.7023 0.9989 2070551 Maybridge1_001842 Cc1nn(C)c(=O)c2noc(/C=C/c3ccc(Cl)c(Cl)c3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L17 compound treatment 968631.0 353000.0 0.5 987996.0 385000.0 0.54 0.7343 0.9994 1168720 Maybridge1_001843 Cc1cc(Oc2ccc(NS(=O)(=O)c3cccc4cccnc34)cn2)cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L18 compound treatment 923796.0 308000.0 0.44 962038.0 359000.0 0.5 0.6636 0.9978 2070552 Maybridge1_001844 Cc1cc(N/C=N/O)c2ccccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L19 compound treatment 958724.0 343000.0 0.49 967513.0 364000.0 0.51 0.7041 0.9998 1497053 Maybridge1_001845 CC(C)(C)c1ccc(COc2cccnc2N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L20 compound treatment 939617.0 324000.0 0.46 963603.0 360000.0 0.5 0.681 0.999 2070553 Maybridge1_001846 Cc1cc(O)n(n1)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L21 compound treatment 1001605.0 386000.0 0.55 983207.0 380000.0 0.53 0.7627 0.9999 2070554 Maybridge1_001847 Cn1c(S)nnc1SCc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L22 compound treatment 943318.0 328000.0 0.47 942359.0 339000.0 0.47 0.6638 1.0 1428836 Maybridge1_001848 Cc1nc(cs1)c2ccc3NC(=O)CCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L23 mock treatment 1006806.0 391000.0 0.56 928871.0 326000.0 0.45 0.7143 0.995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 L24 mock treatment 159770.0 -456000.0 -0.65 156459.0 -447000.0 -0.62 -0.8992 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M01 compound treatment 827901.0 212000.0 0.3 845554.0 242000.0 0.34 0.4523 0.9984 2070555 Maybridge1_001849 Clc1ccc(cc1)C(=O)CC(=S)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M02 compound treatment 859080.0 243000.0 0.35 899704.0 297000.0 0.41 0.537 0.9961 2070556 Maybridge1_001850 CC(C)(C)c1cc(OC(=O)c2ccc(Cl)cc2Cl)c(cc1OC(=O)c3ccc(Cl)cc3Cl)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M03 compound treatment 895931.0 280000.0 0.4 951948.0 349000.0 0.49 0.6256 0.9951 2070557 Maybridge1_001851 Cc1ccc(=O)n(Cc2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M04 compound treatment 874169.0 258000.0 0.37 906435.0 303000.0 0.42 0.5588 0.9975 2070558 Maybridge1_001852 Nc1c(C#N)cnn1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M05 compound treatment 866816.0 251000.0 0.36 916799.0 314000.0 0.44 0.5617 0.9949 1397157 Maybridge1_001853 Fc1cccc(Cl)c1COc2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M06 compound treatment 861157.0 245000.0 0.35 900635.0 297000.0 0.41 0.54 0.9963 1212300 Maybridge1_001854 COc1ccc(Oc2c(Cl)cnn(c3ccc(Cl)cc3)c2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M07 compound treatment 934896.0 319000.0 0.45 944137.0 341000.0 0.48 0.6571 0.9997 1271392 Maybridge1_001855 O=C(Nc1ccccc1)Oc2ccc(CC#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M08 compound treatment 890273.0 274000.0 0.39 922146.0 319000.0 0.44 0.5905 0.9979 2070559 Maybridge1_001856 [O-][N+](=O)c1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M09 compound treatment 919538.0 304000.0 0.43 960499.0 357000.0 0.5 0.6578 0.9975 2070560 Maybridge1_001857 CC(C)Oc1ccccc1Oc2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M10 compound treatment 899755.0 284000.0 0.4 907585.0 304000.0 0.42 0.5857 0.9997 1239145 Maybridge1_001858 Nc1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M11 compound treatment 935531.0 320000.0 0.45 998251.0 395000.0 0.55 0.7111 0.9954 2070561 Maybridge1_001859 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M12 compound treatment 884741.0 269000.0 0.38 988420.0 385000.0 0.54 0.6503 0.9861 1175941 Maybridge1_001860 COc1c(Cl)cc(Cl)c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M13 compound treatment 947798.0 332000.0 0.47 992576.0 389000.0 0.54 0.7178 0.9976 2070562 Maybridge1_001861 Cc1cccc(Oc2ccc(cn2)[N+](=O)[O-])c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M14 compound treatment 877753.0 262000.0 0.37 996922.0 394000.0 0.55 0.6517 0.9821 2070563 Maybridge1_001862 CSc1ncccc1C(=O)c2c(C)nn(c2O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M15 compound treatment 962019.0 346000.0 0.49 1019682.0 416000.0 0.58 0.7589 0.9966 2070564 Maybridge1_001863 Nc1ccc(Oc2cccnc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M16 compound treatment 924884.0 309000.0 0.44 1018123.0 415000.0 0.58 0.72 0.9908 1616749 Maybridge1_001864 CCOC(=O)c1c[nH]c2c(F)ccc(F)c2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M17 compound treatment 931118.0 315000.0 0.45 1016677.0 413000.0 0.58 0.7248 0.9923 2070565 Maybridge1_001865 CCOC(=O)/C(=C/Nc1ccc(Oc2cccnc2)nc1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M18 compound treatment 893758.0 278000.0 0.4 974290.0 371000.0 0.52 0.6455 0.9911 2070566 Maybridge1_001866 CCOC(CN(C(=O)c1ccc(cc1)[N+](=O)[O-])c2ccc(F)cc2)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M19 compound treatment 957535.0 342000.0 0.49 1033233.0 430000.0 0.6 0.7677 0.9946 2070567 Maybridge1_001867 Cc1ccc(OCc2c(F)cccc2Cl)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M20 compound treatment 907193.0 291000.0 0.41 954657.0 351000.0 0.49 0.6396 0.9965 2070568 Maybridge1_001868 CN(C)/C=N/c1ncc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M21 compound treatment 945822.0 330000.0 0.47 976999.0 374000.0 0.52 0.7005 0.9986 2070569 Maybridge1_001869 Cc1ccc(OS(=O)(=O)c2ccc(F)cc2)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M22 compound treatment 900712.0 285000.0 0.41 964556.0 361000.0 0.5 0.6429 0.9941 2070570 Maybridge1_001870 Clc1ccc(cc1)C(=O)Oc2ccc(/C=C/3\NC(=O)NC3=O)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M23 mock treatment 987300.0 371000.0 0.53 993199.0 390000.0 0.54 0.7582 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 M24 mock treatment 744986.0 129000.0 0.18 736104.0 133000.0 0.19 0.261 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N01 compound treatment 871990.0 256000.0 0.36 831158.0 228000.0 0.32 0.4824 0.9977 1425744 Maybridge1_001871 Cc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N02 compound treatment 883260.0 267000.0 0.38 874066.0 271000.0 0.38 0.5361 1.0 2070571 Maybridge1_001872 Fc1ccc(cc1F)C(=O)CSC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N03 compound treatment 928522.0 313000.0 0.44 953171.0 350000.0 0.49 0.6596 0.9989 2070572 Maybridge1_001873 CC/1=NN(C(=O)\C1=C\c2ccc(O)cc2)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N04 compound treatment 898139.0 282000.0 0.4 907210.0 304000.0 0.42 0.5837 0.9996 1917780 Maybridge1_001874 CCOC(=O)CNC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N05 compound treatment 926464.0 311000.0 0.44 963459.0 360000.0 0.5 0.6677 0.9979 1067559 Maybridge1_001875 CCOc1ccc(N=c2ssc(SC)c2c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N06 compound treatment 911225.0 295000.0 0.42 866233.0 263000.0 0.37 0.5565 0.9977 2070573 Maybridge1_001876 CCOC(=O)CNC(=O)c1ccccc1NCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N07 compound treatment 959886.0 344000.0 0.49 929595.0 326000.0 0.46 0.6679 0.9994 2070574 Maybridge1_001877 Fc1ccc(NC(=O)CSc2ccc(Cl)cc2)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N08 compound treatment 944028.0 328000.0 0.47 897146.0 294000.0 0.41 0.6199 0.9979 1313213 Maybridge1_001878 Cc1ccc(Sc2ncccc2C(=O)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N09 compound treatment 942028.0 326000.0 0.46 930759.0 328000.0 0.46 0.6511 1.0 1213969 Maybridge1_001879 COC(=O)COc1c(C)cc(cc1C)c2nn(C)c(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N10 compound treatment 928237.0 312000.0 0.44 930661.0 327000.0 0.46 0.6371 0.9999 2070575 Maybridge1_001880 CSc1nc([nH]c(=O)c1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N11 compound treatment 962738.0 347000.0 0.49 952511.0 349000.0 0.49 0.6933 1.0 2070576 Maybridge1_001881 FC(F)(F)Sc1ccc(NC(=O)Nc2ccc(Sc3ccc(Cl)cc3)nc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N12 compound treatment 904863.0 289000.0 0.41 953460.0 350000.0 0.49 0.6361 0.9963 2070577 Maybridge1_001882 Clc1ccc(SCc2cc(=O)[nH]c(=O)[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N13 compound treatment 1114701.0 499000.0 0.71 1134957.0 532000.0 0.74 1.0261 0.9998 2070578 Maybridge1_001883 CSc1nc2nccc(N)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N14 compound treatment 939160.0 323000.0 0.46 947166.0 344000.0 0.48 0.6644 0.9998 2070579 Maybridge1_001884 OCCSc1ccc(Cl)cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N15 compound treatment 1004690.0 389000.0 0.55 941863.0 339000.0 0.47 0.725 0.9969 2070580 Maybridge1_001885 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2NS(=O)(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N16 compound treatment 1005025.0 389000.0 0.55 1033178.0 430000.0 0.6 0.8154 0.9992 1510809 Maybridge1_001886 CCOC(=O)C1=C(N)CC(=C(N)C1)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N17 compound treatment 963661.0 348000.0 0.49 995196.0 392000.0 0.55 0.7364 0.9988 2070581 Maybridge1_001887 COc1cccc(c1)C(=O)N/N=C(\C)/c2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N18 compound treatment 948180.0 332000.0 0.47 978109.0 375000.0 0.52 0.704 0.9987 2070582 Maybridge1_001888 CC(=O)c1cc(C#N)c(=O)[nH]c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N19 compound treatment 963680.0 348000.0 0.49 1003948.0 401000.0 0.56 0.745 0.9981 1163521 Maybridge1_001889 Cc1cccc(COc2cccnc2N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N20 compound treatment 919863.0 304000.0 0.43 954941.0 352000.0 0.49 0.6526 0.998 2070583 Maybridge1_001890 Cc1cc(O)n(n1)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N21 compound treatment 978276.0 362000.0 0.52 977802.0 375000.0 0.52 0.7339 1.0 2070584 Maybridge1_001891 Cn1c(S)nnc1SCc2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N22 compound treatment 915701.0 300000.0 0.43 959257.0 356000.0 0.5 0.6527 0.9971 2070585 Maybridge1_001892 COc1cccc(CC(=O)N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N23 mock treatment 1008931.0 393000.0 0.56 965414.0 362000.0 0.51 0.7525 0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 N24 mock treatment 731846.0 116000.0 0.17 716633.0 113000.0 0.16 0.2285 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O01 compound treatment 837545.0 222000.0 0.32 831759.0 229000.0 0.32 0.4484 1.0 2070586 Maybridge1_001893 COc1ccc(Br)c(c1)c2nnc(o2)c3ccccc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O02 compound treatment 801958.0 186000.0 0.26 866341.0 263000.0 0.37 0.4467 0.9871 2070587 Maybridge1_001894 CC(C)(C)c1cc(OS(=O)(=O)c2ccc(Cl)cc2)c(cc1OS(=O)(=O)c3ccc(Cl)cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O03 compound treatment 866808.0 251000.0 0.36 931702.0 329000.0 0.46 0.5764 0.9924 2070588 Maybridge1_001895 Cc1ccc(=O)n(Cc2ccc(Cl)c(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O04 compound treatment 890527.0 275000.0 0.39 906435.0 303000.0 0.42 0.5753 0.9992 2070589 Maybridge1_001896 Nc1nn(cc1C#N)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O05 compound treatment 912474.0 297000.0 0.42 920644.0 317000.0 0.44 0.6114 0.9997 1152248 Maybridge1_001897 Clc1ccc(COc2ccc(CC#N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O06 compound treatment 864418.0 249000.0 0.35 873939.0 271000.0 0.38 0.517 0.9995 2070590 Maybridge1_001898 CC(C)(C)c1cc(Cl)c(OS(=O)(=O)c2ccc(Cl)cc2)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O07 compound treatment 930849.0 315000.0 0.45 928781.0 326000.0 0.45 0.6379 1.0 2070591 Maybridge1_001899 FC(F)(F)c1ccc(/C=C(\C#N)/c2ccc(OCc3ccc(Cl)cc3)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O08 compound treatment 896655.0 281000.0 0.4 878872.0 276000.0 0.38 0.5543 0.9998 2070592 Maybridge1_001900 [O-][N+](=O)c1cc(Cl)c(cc1Sc2ccc(Cl)cc2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O09 compound treatment 924354.0 309000.0 0.44 943307.0 340000.0 0.47 0.6457 0.9992 2070593 Maybridge1_001901 C/C(=N/O)/c1ccn(c1)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O10 compound treatment 888962.0 273000.0 0.39 893509.0 290000.0 0.4 0.561 0.9998 2070594 Maybridge1_001902 COc1ccc(Cl)c(OC)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O11 compound treatment 921136.0 305000.0 0.43 927006.0 324000.0 0.45 0.6264 0.9998 2070595 Maybridge1_001903 Cc1ccc(Sc2ccc(cn2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O12 compound treatment 871447.0 256000.0 0.36 900274.0 297000.0 0.41 0.55 0.9979 2070596 Maybridge1_001904 COc1c(Br)cc([N+](=O)[O-])c(OC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O13 compound treatment 917940.0 302000.0 0.43 932575.0 329000.0 0.46 0.6286 0.9994 2070597 Maybridge1_001905 [O-][N+](=O)c1ccc(Oc2cccc(Cl)c2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O14 compound treatment 883729.0 268000.0 0.38 944590.0 341000.0 0.48 0.6061 0.9939 2070598 Maybridge1_001906 CN(C)/C=C(/Sc1nnc(s1)n2cccc2)\C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O15 compound treatment 931873.0 316000.0 0.45 961436.0 358000.0 0.5 0.6711 0.9986 2070599 Maybridge1_001907 Nc1ccc(Oc2ccc(Br)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O16 compound treatment 906019.0 290000.0 0.41 933451.0 330000.0 0.46 0.6175 0.9985 2070600 Maybridge1_001908 Clc1ccc(cc1Cl)c2csc(=S)n2Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O17 compound treatment 931542.0 316000.0 0.45 985445.0 382000.0 0.53 0.6945 0.9964 2070601 Maybridge1_001909 COC(=O)c1ccc(Cl)cc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O18 compound treatment 895150.0 279000.0 0.4 933687.0 330000.0 0.46 0.6068 0.9973 2070602 Maybridge1_001910 Fc1ccc(NC(=O)CC#N)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O19 compound treatment 948330.0 333000.0 0.47 966777.0 364000.0 0.51 0.6929 0.9994 2070603 Maybridge1_001911 Cc1ccc(COc2ccc(C)nc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O20 compound treatment 923142.0 307000.0 0.44 943602.0 340000.0 0.47 0.6447 0.9991 2070604 Maybridge1_001912 FC(F)(F)c1cnc(NCc2cccnc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O21 compound treatment 936911.0 321000.0 0.46 943648.0 340000.0 0.47 0.6586 0.9998 2070605 Maybridge1_001913 Cc1ccc(OS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(n1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O22 compound treatment 903390.0 288000.0 0.41 902134.0 299000.0 0.42 0.584 1.0 2070606 Maybridge1_001914 [O-][N+](=O)c1cccnc1Oc2ccccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O23 mock treatment 959686.0 344000.0 0.49 922076.0 319000.0 0.44 0.6603 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 O24 mock treatment 447407.0 -168000.0 -0.24 510313.0 -92900.0 -0.13 -0.2609 -0.9584 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P01 compound treatment 858347.0 243000.0 0.34 812731.0 210000.0 0.29 0.4505 0.9966 1019665 Maybridge1_001915 O=S(=O)(NCc1ccccc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P02 compound treatment 852745.0 237000.0 0.34 854337.0 251000.0 0.35 0.4859 0.9998 1595756 Maybridge1_001916 CC(C)(C)c1ccc(Oc2ccc(NC(=O)Cc3cccs3)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P03 compound treatment 865999.0 250000.0 0.36 830793.0 228000.0 0.32 0.476 0.9984 2070607 Maybridge1_001917 COc1ccc(/C=C/2\C(=NN(C2=O)c3cccc(Cl)c3)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P04 compound treatment 882865.0 267000.0 0.38 850919.0 248000.0 0.35 0.5128 0.9989 2070608 Maybridge1_001918 CCOC(=O)CNC(=O)c1cccnc1SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P05 compound treatment 923593.0 308000.0 0.44 877107.0 274000.0 0.38 0.5796 0.9977 1552765 Maybridge1_001919 COc1ccccc1NC(=S)N2CC(C)(C)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P06 compound treatment 925576.0 310000.0 0.44 873323.0 270000.0 0.38 0.5779 0.997 2070609 Maybridge1_001920 CCOC(=O)CNC(=O)c1ccccc1N(CC=C)C(=O)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P07 compound treatment 945497.0 330000.0 0.47 894229.0 291000.0 0.41 0.6185 0.9974 2070610 Maybridge1_001921 CCOC(=O)N1CCCN=C1NNc2cc(F)ccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P08 compound treatment 913726.0 298000.0 0.42 842809.0 240000.0 0.33 0.5359 0.9931 2070611 Maybridge1_001922 FC(F)(F)C1=NN2C(=NC(=O)CC2=N)S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P09 compound treatment 934860.0 319000.0 0.45 878551.0 275000.0 0.38 0.5924 0.9966 1305583 Maybridge1_001923 Cc1cc(cc(C)c1OC(=O)Nc2ccccc2)c3nn(C)c(=O)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P10 compound treatment 904839.0 289000.0 0.41 859892.0 257000.0 0.36 0.5438 0.9976 2070612 Maybridge1_001924 CCOC(=O)c1nn(c2ccc(cc2)C(C)(C)C)c(=N)c(C#N)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P11 compound treatment 929156.0 313000.0 0.45 856284.0 253000.0 0.35 0.5647 0.9933 2070613 Maybridge1_001925 Cc1ccc(Sc2ccc(NC(=O)Nc3ccc(SC(F)(F)F)cc3)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P12 compound treatment 923222.0 307000.0 0.44 850261.0 247000.0 0.34 0.5528 0.9931 2070614 Maybridge1_001926 CN(C)/C=N/c1ncccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P13 compound treatment 939069.0 323000.0 0.46 858172.0 255000.0 0.36 0.5765 0.9919 2070615 Maybridge1_001927 Nc1nnc(SCC(=O)Nc2ccc(F)c(F)c2F)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P14 compound treatment 912465.0 297000.0 0.42 871329.0 268000.0 0.37 0.5627 0.9982 2070616 Maybridge1_001928 Clc1ccc(nc1)S(=O)(=O)CCOC(=O)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P15 compound treatment 956711.0 341000.0 0.48 870535.0 267000.0 0.37 0.6064 0.9916 2070617 Maybridge1_001929 COC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P16 compound treatment 931765.0 316000.0 0.45 900585.0 297000.0 0.41 0.611 0.9992 2070618 Maybridge1_001930 Nc1nc(cs1)c2ccc(Br)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P17 compound treatment 1005078.0 389000.0 0.55 912180.0 309000.0 0.43 0.6961 0.9923 2070619 Maybridge1_001931 OC(=O)CC/C(=N\Nc1ccc(cc1)[N+](=O)[O-])/c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P18 compound treatment 958581.0 343000.0 0.49 895664.0 292000.0 0.41 0.6331 0.9961 2070620 Maybridge1_001932 NC(=N)NCCS(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P19 compound treatment 985707.0 370000.0 0.53 888936.0 286000.0 0.4 0.6537 0.9906 2070621 Maybridge1_001933 CN(C)/C=N/c1ncccc1OCc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P20 compound treatment 937774.0 322000.0 0.46 875238.0 272000.0 0.38 0.592 0.9956 1950715 Maybridge1_001934 Cc1cc(O)n(n1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P21 compound treatment 945998.0 330000.0 0.47 898389.0 295000.0 0.41 0.6231 0.9979 2070622 Maybridge1_001935 Cn1c(S)nnc1SCc2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P22 compound treatment 954752.0 339000.0 0.48 890608.0 287000.0 0.4 0.6243 0.9958 2070623 Maybridge1_001936 COc1ccc(C(=O)O)c(Cl)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P23 mock treatment 928022.0 312000.0 0.44 851685.0 248000.0 0.35 0.559 0.9925 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.546 P24 mock treatment 233091.0 -383000.0 -0.54 392536.0 -211000.0 -0.29 -0.5926 -0.9581 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A01 compound treatment 913380.0 323000.0 0.46 804343.0 244000.0 0.34 0.5652 0.989 1585994 Maybridge1_001937 COc1cccc(CC(=O)NN)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A02 compound treatment 876780.0 286000.0 0.41 784898.0 224000.0 0.31 0.5092 0.9915 2070624 Maybridge1_001938 CCCCCc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A03 compound treatment 881567.0 291000.0 0.41 798602.0 238000.0 0.33 0.5276 0.994 1506162 Maybridge1_001939 CCOC(=O)C1=C(O)C(=O)N(C1)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A04 compound treatment 883147.0 293000.0 0.42 797876.0 237000.0 0.33 0.5284 0.9935 2070625 Maybridge1_001940 CCCCCCN(CCCCCC)c1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A05 compound treatment 930768.0 340000.0 0.48 816138.0 256000.0 0.36 0.5943 0.9887 1271035 Maybridge1_001941 NC(=O)C1=C(O)C(=O)N(C1)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A06 compound treatment 959859.0 369000.0 0.53 848728.0 288000.0 0.4 0.6557 0.9913 2070626 Maybridge1_001942 C/C(=N/O)/c1cc(cc2c1CCC2(C)C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A07 compound treatment 969701.0 379000.0 0.54 858501.0 298000.0 0.42 0.6753 0.9917 1014249 Maybridge1_001943 CCOC(=O)c1[nH]c(C)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A08 compound treatment 978495.0 388000.0 0.55 863963.0 303000.0 0.42 0.6895 0.9914 2070627 Maybridge1_001944 COc1cc(CC/C(=N/O)/C)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A09 compound treatment 974967.0 385000.0 0.55 866715.0 306000.0 0.43 0.6887 0.9925 2070628 Maybridge1_001945 COC(=O)c1cc2ccccc2cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A10 compound treatment 966158.0 376000.0 0.53 874534.0 314000.0 0.44 0.6875 0.9951 1168073 Maybridge1_001946 CCCc1c2CCCCc2cc3c(=O)cc(oc13)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A11 compound treatment 957175.0 367000.0 0.52 894287.0 334000.0 0.47 0.698 0.9984 2070629 Maybridge1_001947 CC(=O)c1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A12 compound treatment 1001128.0 411000.0 0.58 889304.0 329000.0 0.46 0.7372 0.9928 1280207 Maybridge1_001948 CCOC(=O)c1cc(=O)c2ccc(OCC=C)cc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A13 compound treatment 993515.0 403000.0 0.57 890608.0 330000.0 0.46 0.7309 0.9941 2070630 Maybridge1_001949 O=C1CCCc2[nH]c(=O)c(C#N)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A14 compound treatment 961664.0 371000.0 0.53 900601.0 340000.0 0.47 0.7087 0.9986 2070631 Maybridge1_001950 CCCCCCc1cc2c(C)cc(=O)oc2cc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A15 compound treatment 965675.0 375000.0 0.53 885431.0 325000.0 0.45 0.6978 0.9967 1026728 Maybridge1_001951 c1coc(c1)c2nc3ccccc3nc2c4ccco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A16 compound treatment 971592.0 381000.0 0.54 899268.0 339000.0 0.47 0.7174 0.9976 2070632 Maybridge1_001952 CCCc1cc([N+](=O)[O-])c(O)c2c(=O)cc(oc12)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A17 compound treatment 976249.0 386000.0 0.55 907517.0 347000.0 0.48 0.7302 0.998 1449566 Maybridge1_001953 COC(=O)CSc1cc(C)nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A18 compound treatment 953800.0 363000.0 0.52 903078.0 343000.0 0.48 0.7032 0.9992 1555484 Maybridge1_001954 Brc1ccc(OCc2ccccc2)c(OCc3ccccc3)c1CCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A19 compound treatment 1004618.0 414000.0 0.59 908439.0 348000.0 0.49 0.7596 0.9954 2070633 Maybridge1_001955 CCn1cc(nc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A20 compound treatment 962268.0 372000.0 0.53 870026.0 309000.0 0.43 0.6791 0.9949 2070634 Maybridge1_001956 CC(=O)Nc1ccc(CC=C)c(O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A21 compound treatment 942865.0 352000.0 0.5 848750.0 288000.0 0.4 0.6387 0.994 2070635 Maybridge1_001957 Cn1c2CCCC(=O)c2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A22 compound treatment 914046.0 324000.0 0.46 823608.0 263000.0 0.37 0.5849 0.9937 1190426 Maybridge1_001958 CCCc1ccc(SC(=O)N(C)C)cc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A23 mock treatment 908157.0 318000.0 0.45 802778.0 242000.0 0.34 0.5584 0.9897 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 A24 mock treatment 151356.0 -439000.0 -0.62 138983.0 -422000.0 -0.59 -0.8572 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B01 compound treatment 867703.0 277000.0 0.39 783510.0 223000.0 0.31 0.4987 0.9931 2070636 Maybridge1_001959 CCCCCCc1ccc(cc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B02 compound treatment 859486.0 269000.0 0.38 775120.0 215000.0 0.3 0.4822 0.9926 1913687 Maybridge1_001960 COC(=O)CCC(=O)Nc1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B03 compound treatment 909577.0 319000.0 0.45 834773.0 274000.0 0.38 0.5914 0.9964 2070637 Maybridge1_001961 [O-][N+](=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B04 compound treatment 912577.0 322000.0 0.46 833814.0 273000.0 0.38 0.5935 0.9958 1478461 Maybridge1_001962 O=C1Cc2ccccc2C(N1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B05 compound treatment 901148.0 311000.0 0.44 889886.0 329000.0 0.46 0.6373 0.9998 2070638 Maybridge1_001963 CC(C)(C)c1ccc(O)c(c1)/C(=N/O)/c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B06 compound treatment 929094.0 339000.0 0.48 880867.0 320000.0 0.45 0.6565 0.9993 2070639 Maybridge1_001964 NC(=O)c1ccccc1OCCOc2ccccc2C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B07 compound treatment 993577.0 403000.0 0.57 908883.0 348000.0 0.49 0.749 0.9966 2070640 Maybridge1_001965 Cc1ccc(C)n1c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B08 compound treatment 952454.0 362000.0 0.51 899335.0 339000.0 0.47 0.6982 0.9991 1214488 Maybridge1_001966 O=C1CCC(=O)N1CCc2cnc[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B09 compound treatment 1002230.0 412000.0 0.59 934624.0 374000.0 0.52 0.783 0.9983 2070641 Maybridge1_001967 CCOC(=O)CC(=O)c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B10 compound treatment 974298.0 384000.0 0.55 917687.0 357000.0 0.5 0.7383 0.999 2070642 Maybridge1_001968 OC(=O)CSc1nnc(S)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B11 compound treatment 988218.0 398000.0 0.57 938878.0 378000.0 0.53 0.7731 0.9994 1056525 Maybridge1_001969 COC(=O)c1cccc([N+](=O)[O-])c1c2c(cccc2[N+](=O)[O-])C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B12 compound treatment 964037.0 374000.0 0.53 922781.0 362000.0 0.51 0.733 0.9997 2070643 Maybridge1_001970 N#CC(C1CCC=CC1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B13 compound treatment 995164.0 405000.0 0.58 962604.0 402000.0 0.56 0.8035 0.9999 1287839 Maybridge1_001971 CN1C2CCC1CC(=NO)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B14 compound treatment 970635.0 380000.0 0.54 944184.0 384000.0 0.54 0.7607 1.0 2070644 Maybridge1_001972 CC(=O)c1cc2OCCOc2cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B15 compound treatment 929855.0 339000.0 0.48 938193.0 378000.0 0.53 0.7138 0.9991 2070645 Maybridge1_001973 COc1ccc(NC(=O)C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B16 compound treatment 978079.0 388000.0 0.55 926020.0 365000.0 0.51 0.7503 0.9992 1275916 Maybridge1_001974 OC(=O)CCC(=O)c1ccc2OCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B17 compound treatment 1000360.0 410000.0 0.58 967387.0 407000.0 0.57 0.8135 0.9999 1040375 Maybridge1_001975 Ic1ccc-2c(c1)C(=O)c3ccccc32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B18 compound treatment 936801.0 346000.0 0.49 928138.0 368000.0 0.51 0.7109 0.9998 2070646 Maybridge1_001976 CC1Cc2cc(ccc2O1)/C(=N/O)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B19 compound treatment 978584.0 388000.0 0.55 922913.0 362000.0 0.51 0.7477 0.999 1708515 Maybridge1_001977 CC(=CC1C(C(=O)OCN2C(=O)C3=C(CCCC3)C2=O)C1(C)C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B20 compound treatment 949915.0 360000.0 0.51 903442.0 343000.0 0.48 0.6997 0.9994 2070647 Maybridge1_001978 C/C(=N\O)/C1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B21 compound treatment 986182.0 396000.0 0.56 897529.0 337000.0 0.47 0.7303 0.996 2070648 Maybridge1_001979 CCN(C(=O)C(Cc1ccccc1)C(=O)N(CC)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B22 compound treatment 944941.0 355000.0 0.5 864255.0 304000.0 0.42 0.656 0.9962 1342250 Maybridge1_001980 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B23 mock treatment 923593.0 333000.0 0.47 855511.0 295000.0 0.41 0.6259 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 B24 mock treatment 134006.0 -456000.0 -0.65 146903.0 -414000.0 -0.58 -0.8669 -0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C01 compound treatment 778909.0 189000.0 0.27 713920.0 153000.0 0.21 0.3408 0.9937 2070649 Maybridge1_001981 COC(=O)c1ccc(OC)c(OC)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C02 compound treatment 774554.0 184000.0 0.26 729590.0 169000.0 0.24 0.3519 0.9986 1697962 Maybridge1_001982 CCCCc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C03 compound treatment 838877.0 248000.0 0.35 834622.0 274000.0 0.38 0.5202 0.9992 1018390 Maybridge1_001983 CCOC(=O)c1[nH]c(Cc2[nH]c(C(=O)OCC)c(C)c2CC)c(CC)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C04 compound treatment 722683.0 132000.0 0.19 779412.0 219000.0 0.31 0.3489 0.973 1079253 Maybridge1_001984 CCCCCCCCc1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C05 compound treatment 825918.0 236000.0 0.33 796607.0 236000.0 0.33 0.4696 1.0 1087705 Maybridge1_001985 CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C06 compound treatment 801346.0 211000.0 0.3 794025.0 233000.0 0.33 0.4424 0.9992 2070650 Maybridge1_001986 C/C(=N\OC(=O)c1cccs1)/c2cc(cc3c2CCC3(C)C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C07 compound treatment 860612.0 270000.0 0.38 829373.0 269000.0 0.37 0.5368 0.9999 2070651 Maybridge1_001987 CCN(CC)C(=O)c1[nH]c(C)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C08 compound treatment 844143.0 254000.0 0.36 824791.0 264000.0 0.37 0.5158 0.9999 1330494 Maybridge1_001988 CCn1c(cc(=O)c2cc(OC)ccc12)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C09 compound treatment 872470.0 282000.0 0.4 855329.0 295000.0 0.41 0.5744 0.9999 1210480 Maybridge1_001989 Cc1ccc(Oc2ncccc2N)c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C10 compound treatment 763451.0 173000.0 0.25 797008.0 236000.0 0.33 0.4072 0.9896 1601940 Maybridge1_001990 CCCc1c(OCC=C)ccc2c(=O)cc(oc12)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C11 compound treatment 862156.0 272000.0 0.39 854618.0 294000.0 0.41 0.5633 0.9996 2070652 Maybridge1_001991 Cc1nc(cs1)c2cc(C#N)c(SCCNS(=O)(=O)c3cccc(c3)C(F)(F)F)nc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C12 compound treatment 855132.0 265000.0 0.38 845014.0 284000.0 0.4 0.5468 0.9997 1621208 Maybridge1_001992 COC(=O)c1cc(=O)c2cccc(OC)c2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C13 compound treatment 899536.0 309000.0 0.44 826703.0 266000.0 0.37 0.5733 0.9965 2070653 Maybridge1_001993 CC1(C)OC(=O)C(=Cc2ccc(OCc3ccc(F)cc3)cc2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C14 compound treatment 878992.0 289000.0 0.41 869181.0 309000.0 0.43 0.5946 0.9997 2070654 Maybridge1_001994 COc1ccc(C(=O)C)c(OCc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C15 compound treatment 916623.0 326000.0 0.46 896355.0 336000.0 0.47 0.6592 1.0 1071664 Maybridge1_001995 CC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C16 compound treatment 856809.0 266000.0 0.38 850342.0 290000.0 0.4 0.5537 0.9995 2070655 Maybridge1_001996 Cc1ccc(cc1)S(=O)(=O)N2CCC(=N2)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C17 compound treatment 889591.0 299000.0 0.43 851512.0 291000.0 0.41 0.5878 0.9997 2070656 Maybridge1_001997 Clc1c(Cl)c(Cl)c(C#N)c(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C18 compound treatment 863220.0 273000.0 0.39 802758.0 242000.0 0.34 0.5132 0.9976 2070657 Maybridge1_001998 CC(=O)C1COc2ccc(C)cc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C19 compound treatment 854778.0 264000.0 0.38 860282.0 300000.0 0.42 0.5615 0.9986 683 Maybridge1_001999 Cc1ncc([N+](=O)[O-])n1CCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C20 compound treatment 1412872.0 822000.0 1.17 829039.0 268000.0 0.37 1.0918 0.889 2070658 Maybridge1_002000 CC(=O)Nc1cc(OCC=C)c(cc1C(=O)C)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C21 compound treatment 886724.0 296000.0 0.42 844697.0 284000.0 0.4 0.5782 0.9995 2070659 Maybridge1_002001 Sc1nc(c2cccs2)c(C#N)c(=O)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C22 compound treatment 810528.0 220000.0 0.31 789242.0 229000.0 0.32 0.4469 1.0 2070660 Maybridge1_002002 CCOC(=O)c1cc(=O)c2cc(I)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C23 mock treatment 848534.0 258000.0 0.37 791707.0 231000.0 0.32 0.4875 0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 C24 mock treatment 149711.0 -441000.0 -0.63 137746.0 -423000.0 -0.59 -0.8601 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D01 compound treatment 875635.0 285000.0 0.41 784535.0 224000.0 0.31 0.5077 0.9917 1012007 Maybridge1_002003 COc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D02 compound treatment 851993.0 262000.0 0.37 803346.0 243000.0 0.34 0.5025 0.9989 1022157 Maybridge1_002004 NS(=O)(=O)c1ccc(NC(=O)CCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D03 compound treatment 906699.0 316000.0 0.45 845481.0 285000.0 0.4 0.5991 0.9981 1036639 Maybridge1_002005 O=c1c(c1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D04 compound treatment 858538.0 268000.0 0.38 841803.0 281000.0 0.39 0.547 0.9999 1303231 Maybridge1_002006 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D05 compound treatment 953479.0 363000.0 0.52 895067.0 335000.0 0.47 0.695 0.9987 1663982 Maybridge1_002007 CCOC(=O)Cc1c([nH]c(C)c1C(=O)OCc2ccccc2)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D06 compound treatment 896604.0 306000.0 0.44 876279.0 316000.0 0.44 0.6193 1.0 1010260 Maybridge1_002008 COc1ccccc1OCCOc2ccccc2OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D07 compound treatment 966197.0 376000.0 0.53 911502.0 351000.0 0.49 0.724 0.999 1062747 Maybridge1_002009 c1ccc(cc1)c2nc(c(o2)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D08 compound treatment 923884.0 333000.0 0.47 866100.0 306000.0 0.43 0.6367 0.9986 1183034 Maybridge1_002010 OC1CCC(=O)N1CCc2cnc[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D09 compound treatment 977296.0 387000.0 0.55 920969.0 360000.0 0.5 0.7445 0.999 1038951 Maybridge1_002011 CCOC(=O)CC(=O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D10 compound treatment 950700.0 360000.0 0.51 919459.0 359000.0 0.5 0.7163 0.9999 1126784 Maybridge1_002012 OC(=O)CC(Sc1nnc(S)s1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D11 compound treatment 980044.0 390000.0 0.55 942581.0 382000.0 0.53 0.7686 0.9998 1696384 Maybridge1_002013 CCN(CC)CCN(C)CC1c2ccccc2Oc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D12 compound treatment 907535.0 317000.0 0.45 941734.0 381000.0 0.53 0.6948 0.9966 2070661 Maybridge1_002014 O=C1/C(=C\C2CCC=CC2)/Cc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D13 compound treatment 967504.0 377000.0 0.54 938477.0 378000.0 0.53 0.7519 1.0 2070662 Maybridge1_002015 CC(C)C(C#N)C(C#N)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D14 compound treatment 941339.0 351000.0 0.5 911724.0 351000.0 0.49 0.6992 1.0 1561456 Maybridge1_002016 Nc1ccc2OCCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D15 compound treatment 968377.0 378000.0 0.54 930894.0 370000.0 0.52 0.7453 0.9998 1084645 Maybridge1_002017 [O-][N+](=O)c1ccc(OCc2ccccc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D16 compound treatment 951637.0 361000.0 0.51 940120.0 380000.0 0.53 0.7376 0.9999 1720787 Maybridge1_002018 Brc1cc2OCCOc2cc1C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D17 compound treatment 985528.0 395000.0 0.56 966371.0 406000.0 0.57 0.7976 1.0 1060198 Maybridge1_002019 COC(=O)c1cccc2C(=O)c3ccccc3-c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D18 compound treatment 968086.0 378000.0 0.54 912896.0 352000.0 0.49 0.7273 0.999 2070663 Maybridge1_002020 CCCCCc1ccc(cc1)C(C)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D19 compound treatment 1101941.0 512000.0 0.73 1042830.0 482000.0 0.67 0.99 0.9992 1542963 Maybridge1_002021 COc1ccc2c(c1)nnc3nnc(SCC(=O)N4CCOCC4)n32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D20 compound treatment 985012.0 395000.0 0.56 903610.0 343000.0 0.48 0.7351 0.9969 1647393 Maybridge1_002022 CCC1(CC2CC3C1)CC(C2)(C3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D21 compound treatment 984892.0 394000.0 0.56 931155.0 371000.0 0.52 0.7622 0.9992 1026941 Maybridge1_002023 Clc1ccc2[nH]c3ccc(Cl)cc3c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D22 compound treatment 964171.0 374000.0 0.53 877824.0 317000.0 0.44 0.6888 0.9958 1780030 Maybridge1_002024 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D23 mock treatment 991414.0 401000.0 0.57 895947.0 335000.0 0.47 0.734 0.9952 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 D24 mock treatment 147134.0 -443000.0 -0.63 141885.0 -419000.0 -0.58 -0.8586 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E01 compound treatment 886562.0 296000.0 0.42 811488.0 251000.0 0.35 0.5453 0.9958 1371050 Maybridge1_002025 COc1ccc(C(=O)N)c(Cl)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E02 compound treatment 867976.0 278000.0 0.39 817632.0 257000.0 0.36 0.5327 0.9988 1675178 Maybridge1_002026 CCCc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E03 compound treatment 926909.0 337000.0 0.48 890709.0 330000.0 0.46 0.664 0.9998 1018385 Maybridge1_002027 CCOC(=O)c1[nH]c(C)c(CC)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E04 compound treatment 904713.0 314000.0 0.45 866023.0 305000.0 0.43 0.6173 0.9997 1079173 Maybridge1_002028 CCCCCCc1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E05 compound treatment 955328.0 365000.0 0.52 919714.0 359000.0 0.5 0.7212 0.9998 1330795 Maybridge1_002029 CCCCN1CC(=C(O)C1=O)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E06 compound treatment 885975.0 296000.0 0.42 879288.0 319000.0 0.44 0.6116 0.9996 2070664 Maybridge1_002030 C/C(=N\OC(=O)C(F)(F)F)/c1cc(cc2c1CCC2(C)C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E07 compound treatment 948087.0 358000.0 0.51 927586.0 367000.0 0.51 0.7217 1.0 1032259 Maybridge1_002031 CC(=O)NC(CO)C(=O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E08 compound treatment 946007.0 356000.0 0.51 939626.0 379000.0 0.53 0.7314 0.9998 1074369 Maybridge1_002032 Cc1c(OCc2ccccc2)cccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E09 compound treatment 964517.0 374000.0 0.53 941119.0 381000.0 0.53 0.7515 1.0 2070665 Maybridge1_002033 Cc1ccc(Oc2ncccc2C(F)(F)F)c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E10 compound treatment 953809.0 363000.0 0.52 906299.0 346000.0 0.48 0.7064 0.9994 2070666 Maybridge1_002034 COc1ccc(C(=O)C)c(NC(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E11 compound treatment 980940.0 391000.0 0.56 943169.0 383000.0 0.53 0.7701 0.9998 2070667 Maybridge1_002035 Cc1nc(c(o1)c2ccccc2)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E12 compound treatment 937766.0 347000.0 0.49 961253.0 401000.0 0.56 0.7445 0.9981 1026166 Maybridge1_002036 [O-][N+](=O)c1cc(OCc2ccccc2)c(OCc3ccccc3)c(OCc4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E13 compound treatment 966604.0 376000.0 0.53 945080.0 385000.0 0.54 0.7575 1.0 2070668 Maybridge1_002037 Cc1cc(Oc2ncccc2[N+](=O)[O-])cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E14 compound treatment 969009.0 379000.0 0.54 952736.0 392000.0 0.55 0.7675 1.0 1174165 Maybridge1_002038 CCCc1c(SC(=O)N(C)C)ccc2c(C)cc(=O)oc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E15 compound treatment 1019122.0 429000.0 0.61 1019597.0 459000.0 0.64 0.8838 0.9997 2070669 Maybridge1_002039 CSc1cc(C)nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E16 compound treatment 1002470.0 412000.0 0.59 975499.0 415000.0 0.58 0.8236 1.0 2070670 Maybridge1_002040 CCCc1c(O)c(ccc1SC(=O)N(C)C)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E17 compound treatment 1030224.0 440000.0 0.63 980153.0 420000.0 0.59 0.8561 0.9994 2070671 Maybridge1_002041 Oc1ccc(cc1)n2nnnc2SCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E18 compound treatment 1004335.0 414000.0 0.59 967659.0 407000.0 0.57 0.8177 0.9998 1434029 Maybridge1_002042 CCCc1c(O)ccc2c(=O)cc(oc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E19 compound treatment 980402.0 390000.0 0.55 953846.0 393000.0 0.55 0.78 1.0 1404645 Maybridge1_002043 CC(C)(C)c1ccc(Oc2cnn(c3ccccc3)c(=O)c2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E20 compound treatment 953639.0 363000.0 0.52 957535.0 397000.0 0.55 0.7568 0.9994 2070672 Maybridge1_002044 CCOC(=O)c1ccc2oc3ccc(O)cc3c(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E21 compound treatment 968387.0 378000.0 0.54 941716.0 381000.0 0.53 0.756 1.0 1027240 Maybridge1_002045 CCCCCCCCCCc1ccc(cc1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E22 compound treatment 981209.0 391000.0 0.56 921057.0 361000.0 0.5 0.7485 0.9988 1016459 Maybridge1_002046 CCC(=O)NNc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E23 mock treatment 931353.0 341000.0 0.48 892411.0 332000.0 0.46 0.6701 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 E24 mock treatment 130182.0 -460000.0 -0.65 156501.0 -404000.0 -0.56 -0.8612 -0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F01 compound treatment 907407.0 317000.0 0.45 803399.0 243000.0 0.34 0.5583 0.9901 1627859 Maybridge1_002047 CCOc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F02 compound treatment 842649.0 252000.0 0.36 814136.0 254000.0 0.35 0.5037 1.0 1177385 Maybridge1_002048 COC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F03 compound treatment 943778.0 353000.0 0.5 879663.0 319000.0 0.45 0.6701 0.9982 1053852 Maybridge1_002049 N#CC(=c1ccc(=C(C#N)C#N)cc1)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F04 compound treatment 912397.0 322000.0 0.46 845480.0 285000.0 0.4 0.6048 0.9975 1235461 Maybridge1_002050 OC(CN1CCCCCC1)Cn2c3ccc(Br)cc3c4cc(Br)ccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F05 compound treatment 945811.0 355000.0 0.51 904465.0 344000.0 0.48 0.6966 0.9997 1532455 Maybridge1_002051 COC(=O)CCc1c([nH]c(C)c1C(=O)OC(C)(C)C)C(=O)OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F06 compound treatment 924751.0 334000.0 0.48 885692.0 325000.0 0.45 0.6569 0.9997 2070673 Maybridge1_002052 CC(=O)Nc1cccc(OCCOc2cccc(NC(=O)C)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F07 compound treatment 1005789.0 415000.0 0.59 942644.0 382000.0 0.53 0.7945 0.9987 1007924 Maybridge1_002053 c1c(noc1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F08 compound treatment 1031346.0 441000.0 0.63 960612.0 400000.0 0.56 0.8379 0.9983 1452323 Maybridge1_002054 Cn1c(=O)c2c(O)cc(=O)oc2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F09 compound treatment 975499.0 385000.0 0.55 935522.0 375000.0 0.52 0.757 0.9997 2070674 Maybridge1_002055 CCCCCc1ccc-2c(Cc3cc(ccc32)C(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F10 compound treatment 930984.0 341000.0 0.48 922544.0 362000.0 0.5 0.6995 0.9998 1114824 Maybridge1_002056 OC(=O)c1ccc(Br)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F11 compound treatment 995585.0 405000.0 0.58 926003.0 365000.0 0.51 0.7679 0.9981 1029662 Maybridge1_002057 CC1(O)c2ccccc2-c3ccccc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F12 compound treatment 970850.0 380000.0 0.54 927006.0 366000.0 0.51 0.744 0.9996 2070675 Maybridge1_002058 CC(N1CCOCC1)C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F13 compound treatment 995287.0 405000.0 0.58 968989.0 408000.0 0.57 0.81 1.0 1039044 Maybridge1_002059 C(CC=C(c1ccccc1)c2ccccc2)C=C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F14 compound treatment 1007953.0 418000.0 0.59 950878.0 390000.0 0.54 0.8048 0.9991 2070676 Maybridge1_002060 CC1(C)CC(C)(c2cccc3ccccc23)c4cccc5cccc1c45 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F15 compound treatment 1016698.0 426000.0 0.61 964220.0 404000.0 0.56 0.8268 0.9993 1260687 Maybridge1_002061 Cc1cccc(c1)C(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F16 compound treatment 972698.0 382000.0 0.54 928040.0 367000.0 0.51 0.7469 0.9996 1004784 Maybridge1_002062 Oc1c(Cl)c(Cl)c(Cl)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F17 compound treatment 979457.0 389000.0 0.55 924291.0 364000.0 0.51 0.75 0.9991 2070677 Maybridge1_002063 Oc1cc(cc2C(=O)c3cc(ccc3-c21)[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F18 compound treatment 1006502.0 416000.0 0.59 933693.0 373000.0 0.52 0.7864 0.998 2070678 Maybridge1_002064 OCC(O)C(O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F19 compound treatment 1079604.0 489000.0 0.7 1014113.0 454000.0 0.63 0.9392 0.9989 1685691 Maybridge1_002065 COc1ccc2c(c1)nnc3nnc(SCC(=O)NN)n32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F20 compound treatment 988208.0 398000.0 0.57 936910.0 376000.0 0.52 0.7712 0.9993 1084281 Maybridge1_002066 CC(N)C1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F21 compound treatment 1016237.0 426000.0 0.61 939005.0 378000.0 0.53 0.8014 0.9977 1062012 Maybridge1_002067 Brc1ccc2[nH]c3c(Br)cc(Br)cc3c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F22 compound treatment 978068.0 388000.0 0.55 901830.0 341000.0 0.48 0.7264 0.9973 2070679 Maybridge1_002068 CCCCCCCCCCCC(=O)N1CC(=O)NC(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F23 mock treatment 1006450.0 416000.0 0.59 912690.0 352000.0 0.49 0.7657 0.9957 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 F24 mock treatment 150005.0 -440000.0 -0.63 145217.0 -415000.0 -0.58 -0.8524 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G01 compound treatment 856004.0 266000.0 0.38 797540.0 237000.0 0.33 0.5008 0.9978 2070680 Maybridge1_002069 COc1ccc(/C=C/C#N)c(Cl)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G02 compound treatment 822780.0 232000.0 0.33 800118.0 240000.0 0.33 0.4699 1.0 1089966 Maybridge1_002070 CCc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G03 compound treatment 911466.0 321000.0 0.46 874454.0 314000.0 0.44 0.6324 0.9998 2070681 Maybridge1_002071 CC(=O)C1=C(C)NC(=O)C1CC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G04 compound treatment 883972.0 294000.0 0.42 841554.0 281000.0 0.39 0.5723 0.9995 2070682 Maybridge1_002072 Cc1ccc(Br)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G05 compound treatment 899311.0 309000.0 0.44 877283.0 317000.0 0.44 0.623 1.0 1398285 Maybridge1_002073 COC(=O)Cc1c(OC(=O)C)[nH]c(C)c1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G06 compound treatment 849109.0 259000.0 0.37 883584.0 323000.0 0.45 0.5787 0.9949 2070683 Maybridge1_002074 CC1(C)C2CCC1(C)/C(=N/O)/C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G07 compound treatment 907885.0 317000.0 0.45 891019.0 330000.0 0.46 0.6452 0.9999 1472613 Maybridge1_002075 Cc1ccc(OC(C)(C)C(=O)O)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G08 compound treatment 893841.0 303000.0 0.43 885496.0 325000.0 0.45 0.6256 0.9997 1092704 Maybridge1_002076 COc1cc(Br)c(CCC#N)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G09 compound treatment 906256.0 316000.0 0.45 923991.0 363000.0 0.51 0.676 0.9982 1252404 Maybridge1_002077 COc1ccccc1C2OC(=O)CC2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G10 compound treatment 909663.0 319000.0 0.45 904126.0 344000.0 0.48 0.6599 0.9996 2732 Maybridge1_002078 Cc1cc(=O)oc2cc(O)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G11 compound treatment 928245.0 338000.0 0.48 929031.0 368000.0 0.51 0.7031 0.9994 2070684 Maybridge1_002079 O=C(C1COC(=O)C1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G12 compound treatment 939745.0 349000.0 0.5 886341.0 326000.0 0.45 0.6726 0.999 2070685 Maybridge1_002080 COc1ccc2C(=O)C(CCc2c1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G13 compound treatment 959896.0 370000.0 0.53 947696.0 387000.0 0.54 0.7534 0.9999 1639767 Maybridge1_002081 O=C1Cc2ccccc2C(=O)c3ccsc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G14 compound treatment 937656.0 347000.0 0.49 910144.0 350000.0 0.49 0.694 1.0 1686304 Maybridge1_002082 CCOC(=O)c1cc(=O)c2ccc(O)cc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G15 compound treatment 953686.0 363000.0 0.52 965801.0 405000.0 0.57 0.765 0.999 1339494 Maybridge1_002083 CC(=O)Nc1cccc(C)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G16 compound treatment 966100.0 376000.0 0.53 935747.0 375000.0 0.52 0.7478 0.9999 1515846 Maybridge1_002084 CCCc1c(O)ccc2C(=O)CC(C)(CCC(=O)OC)Oc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G17 compound treatment 972337.0 382000.0 0.54 947519.0 387000.0 0.54 0.7657 1.0 1660066 Maybridge1_002085 CCOC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G18 compound treatment 958181.0 368000.0 0.52 938403.0 378000.0 0.53 0.7425 1.0 2070686 Maybridge1_002086 CCCc1c(O)c(ccc1OCc2ccccc2)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G19 compound treatment 951393.0 361000.0 0.51 958905.0 398000.0 0.56 0.7559 0.9992 1397141 Maybridge1_002087 O=C(ON1C(=O)C2C3OC(C=C3)C2C1=O)c4cccnc4Oc5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G20 compound treatment 902394.0 312000.0 0.44 882349.0 322000.0 0.45 0.6311 1.0 2070687 Maybridge1_002088 CS/C(=N/c1ccccc1)/Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G21 compound treatment 958809.0 368000.0 0.52 922984.0 362000.0 0.51 0.7279 0.9998 1080745 Maybridge1_002089 CC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G22 compound treatment 910976.0 321000.0 0.46 895839.0 335000.0 0.47 0.653 0.9999 2070688 Maybridge1_002090 CCCc1ccc(OC)cc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G23 mock treatment 954998.0 365000.0 0.52 898791.0 338000.0 0.47 0.7002 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 G24 mock treatment 133430.0 -457000.0 -0.65 151189.0 -409000.0 -0.57 -0.8632 -0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H01 compound treatment 888740.0 298000.0 0.42 770328.0 210000.0 0.29 0.5069 0.9835 1274795 Maybridge1_002091 CCCOc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H02 compound treatment 833267.0 243000.0 0.35 765054.0 205000.0 0.29 0.4459 0.9955 1254947 Maybridge1_002092 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H03 compound treatment 916936.0 327000.0 0.46 825389.0 265000.0 0.37 0.5895 0.9936 1026066 Maybridge1_002093 CCOC(=O)C1c2ccccc2Oc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H04 compound treatment 8127855.0 7540000.0 10.72 7169050.0 6610000.0 9.22 14.0967 0.9972 1033421 Maybridge1_002094 Nc1cccc2-c3ccccc3C(=O)c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H05 compound treatment 931532.0 341000.0 0.49 873702.0 313000.0 0.44 0.6519 0.9986 2070689 Maybridge1_002095 O=C1N(CCCCCN2C(=O)c3ccccc3S2(=O)=O)S(=O)(=O)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H06 compound treatment 920020.0 330000.0 0.47 819922.0 259000.0 0.36 0.5873 0.9918 2070690 Maybridge1_002096 COc1cccc(OCCOc2cccc(OC)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H07 compound treatment 982959.0 393000.0 0.56 942241.0 382000.0 0.53 0.7712 0.9997 1022179 Maybridge1_002097 CN(C)Cc1cc(O)c(CN(C)C)cc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H08 compound treatment 936001.0 346000.0 0.49 876271.0 316000.0 0.44 0.6589 0.9985 2070691 Maybridge1_002098 O[C@H]1C2C3C4C2C5CC4C([C@@H]3O)C15 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H09 compound treatment 965511.0 375000.0 0.53 861219.0 301000.0 0.42 0.6737 0.9929 1011924 Maybridge1_002099 CC(=O)c1ccc-2c(Cc3ccccc32)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H10 compound treatment 922419.0 332000.0 0.47 888805.0 328000.0 0.46 0.6576 0.9999 1047733 Maybridge1_002100 N#CCCC(CCC#N)(C#N)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H11 compound treatment 964161.0 374000.0 0.53 915007.0 354000.0 0.49 0.7254 0.9993 1520838 Maybridge1_002101 CCC(C#N)(c1ccccc1)c2ccc(N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H12 compound treatment 926180.0 336000.0 0.48 865107.0 305000.0 0.42 0.638 0.9983 1472477 Maybridge1_002102 OC(=O)C1(CC2CC3CC(O)(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H13 compound treatment 949177.0 359000.0 0.51 925159.0 365000.0 0.51 0.7204 1.0 3177555 Maybridge1_002103 Cc1ccc(cc1)S(=O)(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)OCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H14 compound treatment 903282.0 313000.0 0.44 894138.0 334000.0 0.47 0.6436 0.9998 2070693 Maybridge1_002104 [O-][N+](=O)c1ccc2[nH]c3ccc(cc3c2c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H15 compound treatment 986089.0 396000.0 0.56 925966.0 365000.0 0.51 0.7583 0.9988 1073082 Maybridge1_002105 c1csc(c1)c2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H16 compound treatment 953404.0 363000.0 0.52 904016.0 343000.0 0.48 0.7038 0.9993 2070694 Maybridge1_002106 NC(=O)C1CC1(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H17 compound treatment 1001211.0 411000.0 0.58 927879.0 367000.0 0.51 0.7754 0.9979 1041298 Maybridge1_002107 OC(=O)c1cccc2Cc3ccccc3-c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H18 compound treatment 864162.0 274000.0 0.39 849729.0 289000.0 0.4 0.5605 0.9998 2070695 Maybridge1_002108 CCCCCc1ccc(/C=N/O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H19 compound treatment 1007670.0 417000.0 0.59 911002.0 350000.0 0.49 0.7652 0.9954 2070696 Maybridge1_002109 OC(=O)C(F)(F)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H20 compound treatment 960910.0 371000.0 0.53 876255.0 316000.0 0.44 0.6839 0.996 1132443 Maybridge1_002110 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(O)cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H21 compound treatment 976476.0 386000.0 0.55 903205.0 343000.0 0.48 0.7262 0.9976 1421410 Maybridge1_002111 OCC(O)Cn1c2ccccc2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H22 compound treatment 964334.0 374000.0 0.53 819136.0 259000.0 0.36 0.631 0.9821 1405657 Maybridge1_002112 O=C1CN(CC(=O)N1)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H23 mock treatment 982427.0 392000.0 0.56 865743.0 305000.0 0.43 0.6952 0.9911 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 H24 mock treatment 154971.0 -435000.0 -0.62 130244.0 -430000.0 -0.6 -0.8622 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I01 compound treatment 871337.0 281000.0 0.4 799701.0 239000.0 0.33 0.5184 0.996 2070697 Maybridge1_002113 CCOC(=O)c1ccc(OC)c(OC)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I02 compound treatment 857669.0 267000.0 0.38 815284.0 255000.0 0.36 0.52 0.9994 1083770 Maybridge1_002114 N#Cc1nccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I03 compound treatment 921346.0 331000.0 0.47 861373.0 301000.0 0.42 0.6295 0.9984 1679978 Maybridge1_002115 CCOC(=O)C1=C(N)C(=O)N(C1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I04 compound treatment 909407.0 319000.0 0.45 855966.0 295000.0 0.41 0.6121 0.9988 1071677 Maybridge1_002116 CN(C)c1cccc2cccc(N(C)C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I05 compound treatment 937046.0 347000.0 0.49 899160.0 339000.0 0.47 0.6825 0.9998 1007323 Maybridge1_002117 CCOC(=O)c1[nH]c(C)c(C(=O)C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I06 compound treatment 815084.0 225000.0 0.32 891572.0 331000.0 0.46 0.5524 0.9838 2070698 Maybridge1_002118 Cc1oc(nc1CC(=O)O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I07 compound treatment 915918.0 326000.0 0.46 917197.0 357000.0 0.5 0.6791 0.9994 1275946 Maybridge1_002119 OC(C(=O)c1cccs1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I08 compound treatment 894420.0 304000.0 0.43 907884.0 347000.0 0.48 0.6483 0.9984 1204024 Maybridge1_002120 N#CCCc1cccc(OCc2ccccc2)c1OCc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I09 compound treatment 942092.0 352000.0 0.5 938521.0 378000.0 0.53 0.7264 0.9997 2070699 Maybridge1_002121 Clc1ccc(C(=O)NCCSC(=O)c2ccc(Cl)cc2Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I10 compound treatment 934643.0 344000.0 0.49 920556.0 360000.0 0.5 0.7012 0.9999 2070700 Maybridge1_002122 Nc1nnc(s1)c2ccc(o2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I11 compound treatment 947333.0 357000.0 0.51 965077.0 405000.0 0.56 0.7579 0.9986 2070701 Maybridge1_002123 [O-][N+](=O)c1cccnc1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I12 compound treatment 803500.0 213000.0 0.3 871306.0 311000.0 0.43 0.5208 0.9847 1928073 Maybridge1_002124 COC(=O)c1cccc(OC)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I13 compound treatment 939910.0 350000.0 0.5 928700.0 368000.0 0.51 0.7145 0.9999 2070702 Maybridge1_002125 CCCCCc1ccc(cc1)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I14 compound treatment 949514.0 359000.0 0.51 914193.0 354000.0 0.49 0.7099 0.9998 1727984 Maybridge1_002126 COC(=O)c1ccc(cc1)C2=NC(C)(C)CO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I15 compound treatment 857433.0 267000.0 0.38 962730.0 402000.0 0.56 0.6652 0.982 2070703 Maybridge1_002127 [O-][N+](=O)c1ccc(Sc2ccccn2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I16 compound treatment 1005820.0 415000.0 0.59 999325.0 439000.0 0.61 0.8505 0.9998 1698123 Maybridge1_002128 COc1ccc2nc(N)sc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I17 compound treatment 1013176.0 423000.0 0.6 964288.0 404000.0 0.56 0.8233 0.9995 2070704 Maybridge1_002129 Nc1cccnc1Sc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I18 compound treatment 963228.0 373000.0 0.53 942517.0 382000.0 0.53 0.7516 1.0 1022546 Maybridge1_002130 CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I19 compound treatment 949513.0 359000.0 0.51 938722.0 378000.0 0.53 0.7341 0.9999 2070705 Maybridge1_002131 COC(=O)c1cccnc1Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I20 compound treatment 948778.0 358000.0 0.51 935485.0 375000.0 0.52 0.7301 0.9999 2070706 Maybridge1_002132 CS/C(=N/C(C)C)/NC(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I21 compound treatment 973239.0 383000.0 0.54 956067.0 396000.0 0.55 0.775 1.0 1111975 Maybridge1_002133 Cc1cc(C)n(C)c(=O)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I22 compound treatment 952172.0 362000.0 0.51 880265.0 320000.0 0.45 0.6791 0.9975 1018233 Maybridge1_002134 CCN(CC)S(=O)(=O)c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I23 mock treatment 969477.0 379000.0 0.54 918777.0 358000.0 0.5 0.7345 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 I24 mock treatment 139946.0 -450000.0 -0.64 156784.0 -404000.0 -0.56 -0.8512 -0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J01 compound treatment 886870.0 296000.0 0.42 773431.0 213000.0 0.3 0.5081 0.9853 2070707 Maybridge1_002135 CCCCOc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J02 compound treatment 878951.0 289000.0 0.41 795287.0 235000.0 0.33 0.5217 0.9937 1169013 Maybridge1_002136 Cc1c(NS(=O)(=O)c2ccc(NC(=O)CCC(=O)O)cc2)c(=O)n(c3ccccc3)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J03 compound treatment 910744.0 320000.0 0.46 843730.0 283000.0 0.39 0.6014 0.9975 1075281 Maybridge1_002137 Cc1ccc2ncccc2c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J04 compound treatment 862333.0 272000.0 0.39 817015.0 256000.0 0.36 0.5264 0.9992 2070708 Maybridge1_002138 OC(=O)c1cccc2cccc(Br)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J05 compound treatment 884239.0 294000.0 0.42 863660.0 303000.0 0.42 0.5944 1.0 2070709 Maybridge1_002139 CC(C)(C)c1cc2CCc3cc(cc(c1)c23)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J06 compound treatment 911457.0 321000.0 0.46 812991.0 252000.0 0.35 0.5718 0.9918 1056658 Maybridge1_002140 Clc1ccc(OCCOc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J07 compound treatment 941175.0 351000.0 0.5 874011.0 313000.0 0.44 0.6619 0.9978 2070710 Maybridge1_002141 [O-][N+](=O)c1sccc1CS(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J08 compound treatment 937064.0 347000.0 0.49 863035.0 302000.0 0.42 0.6469 0.997 2070711 Maybridge1_002142 COC(F)(C(=O)N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J09 compound treatment 965897.0 376000.0 0.53 893849.0 333000.0 0.46 0.7063 0.9976 1289810 Maybridge1_002143 Brc1ccc(CC(=O)c2ccc-3c(Cc4ccccc43)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J10 compound treatment 912172.0 322000.0 0.46 824733.0 264000.0 0.37 0.5841 0.9942 1007301 Maybridge1_002144 NC(=O)C(CCC#N)(CCC#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J11 compound treatment 932368.0 342000.0 0.49 910400.0 350000.0 0.49 0.6889 1.0 2070712 Maybridge1_002145 CC(=O)/C(=N/NC(=O)CC#N)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J12 compound treatment 965578.0 375000.0 0.53 875302.0 315000.0 0.44 0.6877 0.9953 2070713 Maybridge1_002146 CO[C@H]1CC2(N3CC=C2C=C1)c4cc(OC)c(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)cc4CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J13 compound treatment 949196.0 359000.0 0.51 885391.0 325000.0 0.45 0.6812 0.9982 2070714 Maybridge1_002147 Cc1csc(c1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J14 compound treatment 996376.0 406000.0 0.58 891159.0 331000.0 0.46 0.7343 0.9938 2070715 Maybridge1_002148 Cn1c2ccccc2c3cc(ccc13)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J15 compound treatment 1010790.0 420000.0 0.6 959963.0 399000.0 0.56 0.8166 0.9994 2070716 Maybridge1_002149 Cn1c(nc2ccccc12)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J16 compound treatment 901973.0 312000.0 0.44 903552.0 343000.0 0.48 0.6516 0.9993 1368311 Maybridge1_002150 Clc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J17 compound treatment 976980.0 387000.0 0.55 919617.0 359000.0 0.5 0.7429 0.9989 1055459 Maybridge1_002151 OC(=O)C1Cc2c(CN1)[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J18 compound treatment 962911.0 373000.0 0.53 889411.0 329000.0 0.46 0.6989 0.9974 2070717 Maybridge1_002152 [O-][N+](=O)c1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J19 compound treatment 968979.0 379000.0 0.54 922155.0 362000.0 0.5 0.7373 0.9995 1059900 Maybridge1_002153 OC(=O)c1cc(Br)c(cc1Br)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J20 compound treatment 953518.0 363000.0 0.52 895772.0 335000.0 0.47 0.6957 0.9988 2070718 Maybridge1_002154 Cc1c(NC(=O)/C=N/O)c(=O)n(c2ccccc2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J21 compound treatment 993352.0 403000.0 0.57 905789.0 345000.0 0.48 0.7457 0.9963 1159242 Maybridge1_002155 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3ncccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J22 compound treatment 939015.0 349000.0 0.5 870049.0 309000.0 0.43 0.6558 0.9976 1117231 Maybridge1_002156 BrC1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J23 mock treatment 964267.0 374000.0 0.53 816173.0 256000.0 0.36 0.628 0.9811 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 J24 mock treatment 173998.0 -416000.0 -0.59 161635.0 -399000.0 -0.56 -0.8121 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K01 compound treatment 826910.0 237000.0 0.34 782133.0 222000.0 0.31 0.4564 0.9991 1050460 Maybridge1_002157 OC1(CCNCC1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K02 compound treatment 975440.0 385000.0 0.55 934924.0 374000.0 0.52 0.7564 0.9997 1051267 Maybridge1_002158 Oc1nc2cccnc2nc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K03 compound treatment 864565.0 274000.0 0.39 848460.0 288000.0 0.4 0.5596 0.9999 1003036 Maybridge1_002159 CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K04 compound treatment 859578.0 269000.0 0.38 832670.0 272000.0 0.38 0.539 1.0 1037780 Maybridge1_002160 CCc1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K05 compound treatment 903534.0 313000.0 0.45 852279.0 292000.0 0.41 0.6026 0.999 1010424 Maybridge1_002161 C(CNc1ccccc1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K06 compound treatment 880714.0 290000.0 0.41 864008.0 303000.0 0.42 0.5912 0.9999 2070719 Maybridge1_002162 COc1ccc2nccc(C(=O)C3CC4CCN3C(C4)C=C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K07 compound treatment 838127.0 248000.0 0.35 888144.0 328000.0 0.46 0.5722 0.9917 2070720 Maybridge1_002163 COc1ccc(C)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K08 compound treatment 877323.0 287000.0 0.41 871777.0 311000.0 0.43 0.5955 0.9995 2070721 Maybridge1_002164 COc1c(O)c(C(=O)C)c(OC)c2ccoc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K09 compound treatment 904974.0 315000.0 0.45 901509.0 341000.0 0.48 0.6526 0.9995 2070722 Maybridge1_002165 Fc1ccc(cc1)C(=O)NCCSC(=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K10 compound treatment 849984.0 260000.0 0.37 894603.0 334000.0 0.47 0.5905 0.9934 1231125 Maybridge1_002166 CCOC(=O)c1cc(=O)c2c(O)c(CC=C)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K11 compound treatment 938257.0 348000.0 0.49 932656.0 372000.0 0.52 0.7168 0.9997 2070723 Maybridge1_002167 COc1ccc(Oc2ncccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K12 compound treatment 867580.0 277000.0 0.39 802886.0 242000.0 0.34 0.5177 0.9971 1174068 Maybridge1_002168 COc1c(OC)c(sc1C(=O)O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K13 compound treatment 808370.0 218000.0 0.31 776098.0 216000.0 0.3 0.4318 0.9999 2070724 Maybridge1_002169 COc1cc(ccc1N2CCCC2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K14 compound treatment 920889.0 330000.0 0.47 903383.0 343000.0 0.48 0.6704 1.0 2070725 Maybridge1_002170 CCOCCOc1ccc2oc(cc(=O)c2c1)C(=O)CC(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K15 compound treatment 912370.0 322000.0 0.46 919671.0 359000.0 0.5 0.6779 0.999 1283944 Maybridge1_002171 Cc1cccc(Oc2ncccc2N)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K16 compound treatment 915980.0 326000.0 0.46 896837.0 336000.0 0.47 0.659 1.0 1216999 Maybridge1_002172 CC1(C)CC(=O)C=C(C1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K17 compound treatment 941284.0 351000.0 0.5 922807.0 362000.0 0.51 0.7101 1.0 2070726 Maybridge1_002173 CN(C)/C=N/c1cc(on1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K18 compound treatment 928031.0 338000.0 0.48 902293.0 342000.0 0.48 0.6765 1.0 1502251 Maybridge1_002174 CCn1c(cc(=O)c2cc(OCC=C)ccc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K19 compound treatment 917485.0 327000.0 0.47 904651.0 344000.0 0.48 0.6683 0.9999 2070727 Maybridge1_002175 CC(C)n1cc(nc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K20 compound treatment 933576.0 343000.0 0.49 894395.0 334000.0 0.47 0.6743 0.9997 1514172 Maybridge1_002176 CCC(=O)c1ccc(SC(=O)N(C)C)cc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K21 compound treatment 956757.0 366000.0 0.52 913985.0 353000.0 0.49 0.717 0.9996 1721896 Maybridge1_002177 Oc1ccc(cc1)C(C#N)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K22 compound treatment 929523.0 339000.0 0.48 864433.0 304000.0 0.42 0.6407 0.9979 1075100 Maybridge1_002178 Cc1cc2OCCOc2cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K23 mock treatment 975066.0 385000.0 0.55 897521.0 337000.0 0.47 0.7191 0.9971 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 K24 mock treatment 126127.0 -464000.0 -0.66 187189.0 -373000.0 -0.52 -0.8351 -0.9931 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L01 compound treatment 830722.0 240000.0 0.34 758885.0 198000.0 0.28 0.4373 0.9945 2070728 Maybridge1_002179 CCCCCCOc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L02 compound treatment 844187.0 254000.0 0.36 785313.0 225000.0 0.31 0.4769 0.9975 2070729 Maybridge1_002180 CC(=O)c1ccc2OCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L03 compound treatment 909817.0 319000.0 0.45 808945.0 248000.0 0.35 0.5662 0.9911 2070730 Maybridge1_002181 CCCCCCCCCCc1ccc(cc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L04 compound treatment 872676.0 282000.0 0.4 810609.0 250000.0 0.35 0.5305 0.9975 1027383 Maybridge1_002182 Cn1c(=O)cc(O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L05 compound treatment 906300.0 316000.0 0.45 852144.0 292000.0 0.41 0.6052 0.9988 2070731 Maybridge1_002183 FC(F)(F)c1cnc(/N=C/N2CCOCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L06 compound treatment 823615.0 233000.0 0.33 814912.0 254000.0 0.35 0.4854 0.9994 2070732 Maybridge1_002184 COc1ccc(OCCOc2ccc(OC)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L07 compound treatment 910031.0 320000.0 0.45 835083.0 275000.0 0.38 0.5922 0.9964 1135835 Maybridge1_002185 Sc1nc2cc3OCCOc3cc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L08 compound treatment 892642.0 302000.0 0.43 829459.0 269000.0 0.38 0.5691 0.9977 1660986 Maybridge1_002186 NC1=C(C(=O)NC1=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L09 compound treatment 909004.0 319000.0 0.45 852001.0 291000.0 0.41 0.6078 0.9985 1056325 Maybridge1_002187 O=C(c1ccccc1)c2ccc-3c(Cc4ccccc43)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L10 compound treatment 896338.0 306000.0 0.44 833073.0 273000.0 0.38 0.5764 0.9977 1004888 Maybridge1_002188 N#CCCn1c2ccccc2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L11 compound treatment 939189.0 349000.0 0.5 893898.0 333000.0 0.46 0.6795 0.9995 1101325 Maybridge1_002189 OC1CN(C1)C(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L12 compound treatment 922516.0 332000.0 0.47 878097.0 318000.0 0.44 0.6471 0.9995 2070733 Maybridge1_002190 COC(=O)Cc1nc(sc1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L13 compound treatment 900786.0 310000.0 0.44 877115.0 317000.0 0.44 0.6243 1.0 2070734 Maybridge1_002191 Cc1c(Br)sc(Br)c1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L14 compound treatment 942561.0 352000.0 0.5 881977.0 321000.0 0.45 0.6711 0.9985 1019205 Maybridge1_002192 OC(=O)c1cccc2-c3ccccc3C(=O)c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L15 compound treatment 950598.0 360000.0 0.51 882890.0 322000.0 0.45 0.6801 0.9979 2070735 Maybridge1_002193 c1nnc2nnc3ccccc3n12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L16 compound treatment 854618.0 264000.0 0.38 878159.0 318000.0 0.44 0.5789 0.9966 1329133 Maybridge1_002194 Brc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L17 compound treatment 941009.0 351000.0 0.5 888069.0 328000.0 0.46 0.6756 0.999 2070736 Maybridge1_002195 COc1cc(CC/C(=N\O)/C)ccc1OCc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L18 compound treatment 926820.0 336000.0 0.48 868766.0 308000.0 0.43 0.6423 0.9986 1051539 Maybridge1_002196 CC(C)(C(=O)O)C(C)(C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L19 compound treatment 960478.0 370000.0 0.53 875056.0 315000.0 0.44 0.6823 0.9959 1185814 Maybridge1_002197 Cn1c(=O)c(c(O)c2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L20 compound treatment 938184.0 348000.0 0.49 883778.0 323000.0 0.45 0.6685 0.9989 2070737 Maybridge1_002198 O=C1COc2ccccc2C(=O)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L21 compound treatment 966032.0 376000.0 0.53 896496.0 336000.0 0.47 0.709 0.9979 1340494 Maybridge1_002199 COc1ccc(OCC(O)CN)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L22 compound treatment 971250.0 381000.0 0.54 839368.0 279000.0 0.39 0.6579 0.9868 1100237 Maybridge1_002200 OC(=O)CC1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L23 mock treatment 963084.0 373000.0 0.53 864712.0 304000.0 0.42 0.6747 0.9939 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 L24 mock treatment 159120.0 -431000.0 -0.61 142534.0 -418000.0 -0.58 -0.8459 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M01 compound treatment 835639.0 245000.0 0.35 788649.0 228000.0 0.32 0.4716 0.9989 1623886 Maybridge1_002201 CC1(C)C(Oc2ccc(O)cc21)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M02 compound treatment 831245.0 241000.0 0.34 814645.0 254000.0 0.35 0.4928 0.9999 2070738 Maybridge1_002202 CC(=O)c1ccc(OCc2ccc(F)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M03 compound treatment 895972.0 306000.0 0.43 847365.0 287000.0 0.4 0.5901 0.9991 2070739 Maybridge1_002203 CC(=O)CNC(=O)Cc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M04 compound treatment 843008.0 253000.0 0.36 834909.0 274000.0 0.38 0.5246 0.9995 1013471 Maybridge1_002204 CC(C)(C)C1=CC(=O)C=C(C1=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M05 compound treatment 876414.0 286000.0 0.41 871305.0 311000.0 0.43 0.5941 0.9995 1061166 Maybridge1_002205 Cc1ccc(cc1)S(=O)(=O)NCC(=O)OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M06 compound treatment 862156.0 272000.0 0.39 841267.0 281000.0 0.39 0.5501 1.0 2070740 Maybridge1_002206 O/N=C/1\C(=O)Nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M07 compound treatment 913959.0 324000.0 0.46 864967.0 304000.0 0.42 0.6256 0.9992 2070741 Maybridge1_002207 COc1c2CCCc2c(C)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M08 compound treatment 868265.0 278000.0 0.4 828008.0 267000.0 0.37 0.5432 0.9996 1068351 Maybridge1_002208 CC(=O)c1c(C)cc2cc(C)cc(O)c2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M09 compound treatment 828940.0 239000.0 0.34 877258.0 317000.0 0.44 0.5522 0.9915 2070742 Maybridge1_002209 CC(C)(C)c1ccc(cc1)C(=O)NCCSC(=O)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M10 compound treatment 875651.0 285000.0 0.41 867750.0 307000.0 0.43 0.5898 0.9996 1413315 Maybridge1_002210 CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M11 compound treatment 877736.0 287000.0 0.41 906751.0 346000.0 0.48 0.6304 0.9966 2070743 Maybridge1_002211 CC(C)(C)c1ccc(Oc2ncccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M12 compound treatment 868539.0 278000.0 0.4 842588.0 282000.0 0.39 0.5578 1.0 2070744 Maybridge1_002212 COc1ccc(OC)c2c(=O)cc([nH]c12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M13 compound treatment 937347.0 347000.0 0.49 909680.0 349000.0 0.49 0.6932 1.0 2070745 Maybridge1_002213 CCCCCOc1ccc(cc1)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M14 compound treatment 884847.0 294000.0 0.42 854247.0 294000.0 0.41 0.5857 0.9999 1087097 Maybridge1_002214 OC(=O)C1CC(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M15 compound treatment 909046.0 319000.0 0.45 898833.0 338000.0 0.47 0.654 0.9998 1572932 Maybridge1_002215 Cc1cc(c2ccccc2n1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M16 compound treatment 896347.0 306000.0 0.44 881061.0 321000.0 0.45 0.6237 0.9999 1623580 Maybridge1_002216 CCCc1c(O)ccc2c(=O)cc(sc12)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M17 compound treatment 950261.0 360000.0 0.51 902733.0 342000.0 0.48 0.6993 0.9994 1068971 Maybridge1_002217 [O-][N+](=O)c1ccc(cc1)C(=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M18 compound treatment 905170.0 315000.0 0.45 893303.0 333000.0 0.46 0.6447 0.9998 2070746 Maybridge1_002218 Clc1ccc(cc1)C(=S)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M19 compound treatment 952952.0 363000.0 0.52 896679.0 336000.0 0.47 0.6961 0.9989 2070747 Maybridge1_002219 CC(=O)CCn1cc(nc1C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M20 compound treatment 915415.0 325000.0 0.46 877529.0 317000.0 0.44 0.6394 0.9998 3063067 Maybridge1_002220 CS/C(=N/C(C)C)/NC(C)C.Cc1ccc(cc1)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M21 compound treatment 928237.0 338000.0 0.48 912044.0 351000.0 0.49 0.6864 0.9999 2070748 Maybridge1_002221 CCOC(=O)C(C(NC(=N)S)c1ccsc1)C(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M22 compound treatment 882437.0 292000.0 0.42 846429.0 286000.0 0.4 0.5756 0.9998 1013118 Maybridge1_002222 Clc1cccc2C(=O)c3c(Cl)cccc3C(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M23 mock treatment 965048.0 375000.0 0.53 890248.0 330000.0 0.46 0.7019 0.9973 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 M24 mock treatment 734887.0 144000.0 0.21 717559.0 157000.0 0.22 0.3001 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N01 compound treatment 724738.0 134000.0 0.19 745584.0 185000.0 0.26 0.3176 0.989 2070749 Maybridge1_002223 CCCCCCCCOc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N02 compound treatment 847106.0 257000.0 0.37 802845.0 242000.0 0.34 0.4971 0.9993 1558428 Maybridge1_002224 OCCn1c(=O)c2cc3c(=O)n(CCO)c(=O)c3cc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N03 compound treatment 882776.0 292000.0 0.42 829730.0 269000.0 0.38 0.5595 0.9987 1577930 Maybridge1_002225 CCNc1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N04 compound treatment 845791.0 255000.0 0.36 809468.0 249000.0 0.35 0.5023 0.9997 1031309 Maybridge1_002226 [O-][N+](=O)c1ccc2oc(=O)ccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N05 compound treatment 912802.0 322000.0 0.46 852542.0 292000.0 0.41 0.6122 0.9983 2070750 Maybridge1_002227 CN1CCN(CC1)/C=N/c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N06 compound treatment 832907.0 243000.0 0.34 808824.0 248000.0 0.35 0.4887 1.0 2070751 Maybridge1_002228 Clc1ccc(Cl)c(OCCOc2cc(Cl)ccc2Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N07 compound treatment 924477.0 334000.0 0.48 866124.0 306000.0 0.43 0.6373 0.9985 1223178 Maybridge1_002229 O=C(c1ccccc1)c2ccc3OCCCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N08 compound treatment 905899.0 316000.0 0.45 835337.0 275000.0 0.38 0.5883 0.9969 1045283 Maybridge1_002230 CCCCC(=O)c1ccc(Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N09 compound treatment 938084.0 348000.0 0.49 869555.0 309000.0 0.43 0.6544 0.9977 2070752 Maybridge1_002231 Cc1ccc(cc1)S(=O)(=O)N/N=C/C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N10 compound treatment 887107.0 297000.0 0.42 844084.0 284000.0 0.4 0.578 0.9995 1022399 Maybridge1_002232 N#CCCC1(CCC#N)c2ccccc2-c3ccccc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N11 compound treatment 917982.0 328000.0 0.47 870120.0 310000.0 0.43 0.6347 0.9993 2070753 Maybridge1_002233 COC(=O)c1cccc2cccc(c3cccc4cccc(C(=O)OC)c34)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N12 compound treatment 1615011.0 1020000.0 1.46 1453622.0 893000.0 1.25 1.9111 0.997 2070754 Maybridge1_002234 O=C1CCc2cccc3cccc1c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N13 compound treatment 922922.0 333000.0 0.47 872431.0 312000.0 0.43 0.642 0.9991 2070755 Maybridge1_002235 c1cc(c(s1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N14 compound treatment 862781.0 272000.0 0.39 831001.0 270000.0 0.38 0.5406 0.9999 2070756 Maybridge1_002236 Brc1cc2OCCOc2cc1C(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N15 compound treatment 959000.0 369000.0 0.52 894163.0 334000.0 0.47 0.6997 0.9982 1011927 Maybridge1_002237 Ic1ccc-2c(Cc3ccccc32)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N16 compound treatment 898623.0 308000.0 0.44 862441.0 302000.0 0.42 0.6077 0.9998 1657689 Maybridge1_002238 COc1ccccc1C(=O)c2cc3OCCOc3cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N17 compound treatment 952585.0 362000.0 0.52 895116.0 335000.0 0.47 0.6942 0.9988 2070757 Maybridge1_002239 CCOC(=O)COc1ccccc1C(O)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N18 compound treatment 913640.0 323000.0 0.46 860090.0 300000.0 0.42 0.6205 0.9989 1488255 Maybridge1_002240 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N19 compound treatment 970733.0 380000.0 0.54 883964.0 323000.0 0.45 0.7014 0.9959 1611622 Maybridge1_002241 O=C1N(C(=O)c2cccc3cccc1c23)c4nc5ccccc5[nH]4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N20 compound treatment 942049.0 352000.0 0.5 871494.0 311000.0 0.43 0.6603 0.9975 1323508 Maybridge1_002242 CCC1Oc2ccccc2C(=O)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N21 compound treatment 980302.0 390000.0 0.55 887661.0 327000.0 0.46 0.7147 0.9953 1675924 Maybridge1_002243 Cc1c(NC(=O)CCC(=O)O)c(=O)n(c2ccccc2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N22 compound treatment 957763.0 367000.0 0.52 864333.0 304000.0 0.42 0.669 0.9946 2070758 Maybridge1_002244 CC1CN=C(Nc2ccccc2)S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N23 mock treatment 977959.0 388000.0 0.55 870042.0 309000.0 0.43 0.6949 0.9927 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 N24 mock treatment 563790.0 -26600.0 -0.04 367841.0 -193000.0 -0.27 -0.2168 -0.7988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O01 compound treatment 865309.0 275000.0 0.39 793529.0 233000.0 0.32 0.5062 0.9958 2070759 Maybridge1_002245 COC(=O)CC1C(=O)NC(=C1C(=O)OC)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O02 compound treatment 800768.0 210000.0 0.3 763481.0 203000.0 0.28 0.4117 0.9996 2070760 Maybridge1_002246 CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O03 compound treatment 857996.0 268000.0 0.38 808343.0 248000.0 0.35 0.5135 0.9988 1505833 Maybridge1_002247 COC(=O)C1=C(C)NC(=O)C1CC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O04 compound treatment 797685.0 207000.0 0.29 795444.0 235000.0 0.33 0.4401 0.9986 2070761 Maybridge1_002248 COc1ccc(CO)c(Cl)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O05 compound treatment 863436.0 273000.0 0.39 836812.0 276000.0 0.39 0.547 1.0 2070762 Maybridge1_002249 CC1=C(C(=O)NC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O06 compound treatment 821115.0 231000.0 0.33 798351.0 238000.0 0.33 0.4665 1.0 2070763 Maybridge1_002250 ON=C(c1cccs1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O07 compound treatment 871329.0 281000.0 0.4 845548.0 285000.0 0.4 0.5636 1.0 2070764 Maybridge1_002251 Cc1ccc(Oc2ncccc2[N+](=O)[O-])c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O08 compound treatment 826795.0 236000.0 0.34 811775.0 251000.0 0.35 0.4855 0.9998 2070765 Maybridge1_002252 CCCc1c(cc(cc1[N+](=O)[O-])C(=O)O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O09 compound treatment 882317.0 292000.0 0.42 855647.0 295000.0 0.41 0.5846 1.0 2070766 Maybridge1_002253 CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O10 compound treatment 851506.0 261000.0 0.37 831853.0 271000.0 0.38 0.5301 1.0 1601320 Maybridge1_002254 CCCc1cc(=O)c2ccc(O)cc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O11 compound treatment 886097.0 296000.0 0.42 841216.0 281000.0 0.39 0.5741 0.9994 2070767 Maybridge1_002255 Oc1ncc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O12 compound treatment 855102.0 265000.0 0.38 810154.0 250000.0 0.35 0.5123 0.9992 2070768 Maybridge1_002256 CC/C(=N\NS(=O)(=O)c1ccc(C)cc1)/c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O13 compound treatment 878511.0 288000.0 0.41 872794.0 312000.0 0.44 0.5977 0.9995 2070769 Maybridge1_002257 N#CCCOc1ccc2ccccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O14 compound treatment 859455.0 269000.0 0.38 826548.0 266000.0 0.37 0.5329 0.9999 1495792 Maybridge1_002258 Clc1ccc(cc1)N2CCC(=O)N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O15 compound treatment 899310.0 309000.0 0.44 877266.0 317000.0 0.44 0.623 1.0 1400259 Maybridge1_002259 COc1cc(OC)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O16 compound treatment 856240.0 266000.0 0.38 819039.0 258000.0 0.36 0.5222 0.9997 2070770 Maybridge1_002260 CC(=O)c1c(OCC=C)cc(OCc2ccccc2)c(C(=O)C)c1OCc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O17 compound treatment 915441.0 325000.0 0.46 872314.0 312000.0 0.43 0.6343 0.9995 2070771 Maybridge1_002261 CN(C)/C=N/c1noc(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O18 compound treatment 866240.0 276000.0 0.39 853597.0 293000.0 0.41 0.5664 0.9998 1420016 Maybridge1_002262 S=C(N1CCOCC1)c2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O19 compound treatment 890239.0 300000.0 0.43 872068.0 312000.0 0.43 0.6087 1.0 1175684 Maybridge1_002263 OC(=O)CCC1CCCCCCCCCCC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O20 compound treatment 884021.0 294000.0 0.42 845784.0 285000.0 0.4 0.5766 0.9997 2070772 Maybridge1_002264 CCN(C(=N)SC)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O21 compound treatment 811829.0 221000.0 0.31 821640.0 261000.0 0.36 0.4802 0.9974 2070773 Maybridge1_002265 CCCCCCCCc1ccc(cc1)C(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O22 compound treatment 883189.0 293000.0 0.42 799104.0 239000.0 0.33 0.5297 0.9938 1036785 Maybridge1_002266 OC(=O)c1ccc(Cl)cc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O23 mock treatment 932053.0 342000.0 0.49 862272.0 302000.0 0.42 0.6411 0.9974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 O24 mock treatment 460566.0 -130000.0 -0.18 573130.0 12600.0 0.02 -0.1181 -0.637 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P01 compound treatment 916849.0 326000.0 0.46 781026.0 220000.0 0.31 0.5457 0.98 2070774 Maybridge1_002267 CSc1ncc(Cl)c(n1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P02 compound treatment 887033.0 297000.0 0.42 772367.0 212000.0 0.3 0.5072 0.9848 2070775 Maybridge1_002268 CC(=O)C1C(CC(=CC1=O)/C=C/c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P03 compound treatment 556438.0 -34000.0 -0.05 563458.0 2910.0 0.0 -0.0313 -0.6454 2070776 Maybridge1_002269 CN(C)c1ccc(/C=C/c2ccc3ccccc3[n+]2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P04 compound treatment 883713.0 293000.0 0.42 775836.0 215000.0 0.3 0.5073 0.987 1237161 Maybridge1_002270 OC(COc1ccccc1)CN2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P05 compound treatment 913545.0 323000.0 0.46 799389.0 239000.0 0.33 0.5605 0.9875 2070777 Maybridge1_002271 FC(F)(F)c1cnc(/N=C/N2CCCCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P06 compound treatment 876836.0 286000.0 0.41 796967.0 236000.0 0.33 0.5212 0.9945 1026005 Maybridge1_002272 C(COc1cccc2ccccc12)Oc3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P07 compound treatment 884490.0 294000.0 0.42 808269.0 248000.0 0.35 0.54 0.9955 1023158 Maybridge1_002273 Cc1cc(O)n2ncnc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P08 compound treatment 880024.0 290000.0 0.41 791876.0 231000.0 0.32 0.5194 0.9927 1022119 Maybridge1_002274 OC(=O)c1cc(Br)c(Br)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P09 compound treatment 886821.0 296000.0 0.42 797007.0 236000.0 0.33 0.5313 0.9926 1250550 Maybridge1_002275 OC(=O)C1Cc2ccccc2-c3ccccc3C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P10 compound treatment 912836.0 322000.0 0.46 817119.0 257000.0 0.36 0.5773 0.9925 1028547 Maybridge1_002276 Cc1ccc(C)n1CCn2c(C)ccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P11 compound treatment 872683.0 282000.0 0.4 780029.0 219000.0 0.31 0.5003 0.991 1009725 Maybridge1_002277 OC(=O)c1cccc2cccc(c3cccc4cccc(C(=O)O)c34)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P12 compound treatment 887156.0 297000.0 0.42 810194.0 250000.0 0.35 0.5446 0.9954 1305565 Maybridge1_002278 OC(COc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)CN5CCCCC5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P13 compound treatment 895930.0 306000.0 0.43 820131.0 260000.0 0.36 0.5632 0.9959 1030892 Maybridge1_002279 Cc1cc(=O)oc2cc(N)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P14 compound treatment 887793.0 297000.0 0.42 813862.0 253000.0 0.35 0.5489 0.996 1414498 Maybridge1_002280 Brc1cc2OCCCOc2cc1C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P15 compound treatment 909209.0 319000.0 0.45 817507.0 257000.0 0.36 0.574 0.9932 1067594 Maybridge1_002281 CC(=O)c1ccc-2c(Cc3cc(ccc32)C(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P16 compound treatment 941220.0 351000.0 0.5 807714.0 247000.0 0.34 0.5965 0.9837 1371529 Maybridge1_002282 Cc1ccc(cc1)C(=O)c2cc3OCCOc3cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P17 compound treatment 919687.0 329000.0 0.47 829639.0 269000.0 0.38 0.5965 0.994 2070778 Maybridge1_002283 CC(=O)Nc1cccc([N+](=O)[O-])c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P18 compound treatment 914098.0 324000.0 0.46 840176.0 280000.0 0.39 0.6013 0.9966 1172246 Maybridge1_002284 OC(=O)CCC1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P19 compound treatment 3986271.0 3400000.0 4.83 3344400.0 2780000.0 3.88 6.1602 0.9941 1366365 Maybridge1_002285 CN(C)c1ccc2C(=O)N(C(=O)c3cccc1c32)c4nc5ccccc5[nH]4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P20 compound treatment 944565.0 354000.0 0.5 839745.0 279000.0 0.39 0.6315 0.9919 1503386 Maybridge1_002286 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CC(=O)NC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P21 compound treatment 933107.0 343000.0 0.49 827782.0 267000.0 0.37 0.6082 0.9912 1467705 Maybridge1_002287 Cc1ccc(NC(=O)CCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P22 compound treatment 934398.0 344000.0 0.49 840879.0 280000.0 0.39 0.6224 0.9938 2070779 Maybridge1_002288 CC1CN=C(Nc2ccc(C)cc2)S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P23 mock treatment 924372.0 334000.0 0.47 824482.0 264000.0 0.37 0.5961 0.9921 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.547 P24 mock treatment 165145.0 -425000.0 -0.6 622436.0 61900.0 0.09 -0.3666 -0.6001 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A01 compound treatment 769211.0 204000.0 0.29 843943.0 229000.0 0.32 0.4313 0.9988 2070780 Maybridge1_002993 CC(C)(C)SCCNC(=O)c1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A02 compound treatment 775718.0 211000.0 0.3 839870.0 225000.0 0.31 0.4338 0.9997 2070781 Maybridge1_002994 CS/C(=N/C#N)/NCCSCc1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A03 compound treatment 795773.0 231000.0 0.33 846214.0 231000.0 0.32 0.4602 1.0 1677090 Maybridge1_002995 Clc1ccc(Oc2ccccc2S(=O)(=O)Nc3cc(Cl)cc(Cl)c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A04 compound treatment 787883.0 223000.0 0.32 827065.0 212000.0 0.3 0.4334 0.9994 2070782 Maybridge1_002996 Cc1nc(C)c(s1)c2ccn(n2)C(=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A05 compound treatment 818935.0 254000.0 0.36 869916.0 255000.0 0.36 0.5069 1.0 2070783 Maybridge1_002997 [O-][N+](=O)c1ccc(Sc2nnc(S)s2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A06 compound treatment 844298.0 279000.0 0.4 905644.0 291000.0 0.41 0.5676 0.9999 2070784 Maybridge1_002998 CC(=O)c1nnn(c1C)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A07 compound treatment 872558.0 307000.0 0.44 922931.0 308000.0 0.43 0.6131 1.0 2070785 Maybridge1_002999 Cc1onc(c1C(=O)c2ccccc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A08 compound treatment 873260.0 308000.0 0.44 926633.0 312000.0 0.44 0.6174 1.0 2070786 Maybridge1_003000 CS/C(=N\C#N)/N1CCN(CC1)c2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A09 compound treatment 892767.0 328000.0 0.47 925221.0 310000.0 0.43 0.6357 0.9993 1267859 Maybridge1_003001 Cc1onc(c1C(O)c2ccc(F)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A10 compound treatment 886839.0 322000.0 0.46 895133.0 280000.0 0.39 0.6 0.997 1463907 Maybridge1_003002 O=C(NC1CCCCNC1=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A11 compound treatment 889116.0 324000.0 0.46 931621.0 317000.0 0.44 0.6383 0.9998 2070787 Maybridge1_003003 CC1(C)OC(=O)C(=Cc2cc(Br)cs2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A12 compound treatment 872738.0 308000.0 0.44 904619.0 290000.0 0.4 0.5952 0.9992 2070788 Maybridge1_003004 CS/C(=N\C#N)/N1CCC(CC1)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A13 compound treatment 914617.0 349000.0 0.5 928076.0 313000.0 0.44 0.6605 0.9979 2070789 Maybridge1_003005 CC1(C)C(=C(Br)C(=O)C1(Br)Br)Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A14 compound treatment 930878.0 366000.0 0.52 923876.0 309000.0 0.43 0.6727 0.9957 1086555 Maybridge1_003006 COc1ccc(OC)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A15 compound treatment 942010.0 377000.0 0.54 944776.0 330000.0 0.46 0.7045 0.9971 2070790 Maybridge1_003007 Cc1nn(cc1c2ccccc2)C(=O)Nc3c(C)onc3c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A16 compound treatment 910203.0 345000.0 0.49 947976.0 333000.0 0.46 0.6756 0.9996 2070791 Maybridge1_003008 CS/C(=N/C#N)/NCC#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A17 compound treatment 954130.0 389000.0 0.55 906520.0 292000.0 0.41 0.6789 0.9886 1691204 Maybridge1_003009 CNn1cnc2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A18 compound treatment 917799.0 353000.0 0.5 908055.0 293000.0 0.41 0.6439 0.9949 2070792 Maybridge1_003010 FC(F)(F)c1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A19 compound treatment 919197.0 354000.0 0.5 939160.0 324000.0 0.45 0.676 0.9986 1195410 Maybridge1_003011 Clc1cccc(Cl)c1COc2cccc(c2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A20 compound treatment 916440.0 351000.0 0.5 910666.0 296000.0 0.41 0.6451 0.9955 1225869 Maybridge1_003012 CC(C)(CO)NC(=O)c1cccc(C(=O)NC(C)(C)CO)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A21 compound treatment 901215.0 336000.0 0.48 898950.0 284000.0 0.4 0.6183 0.9957 2070793 Maybridge1_003013 O/N=C/N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A22 compound treatment 872730.0 308000.0 0.44 892180.0 277000.0 0.39 0.5829 0.9981 1355108 Maybridge1_003014 CCNS(=O)(=O)c1cc(Cl)sc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A23 mock treatment 855405.0 290000.0 0.41 848653.0 234000.0 0.33 0.5226 0.9932 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 A24 mock treatment 172730.0 -392000.0 -0.56 158177.0 -457000.0 -0.64 -0.8448 -0.9978 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B01 compound treatment 711427.0 146000.0 0.21 797619.0 183000.0 0.26 0.3275 0.9949 2070794 Maybridge1_003015 Cc1ccc(cc1)C2CC(=O)CC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B02 compound treatment 720337.0 155000.0 0.22 834614.0 220000.0 0.31 0.3729 0.987 2070795 Maybridge1_003016 CC(C)c1ccc(/C=N/NC(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B03 compound treatment 755530.0 190000.0 0.27 866054.0 251000.0 0.35 0.4393 0.9919 2070796 Maybridge1_003017 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)S(=O)(=O)NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B04 compound treatment 745791.0 181000.0 0.26 862341.0 248000.0 0.35 0.4259 0.9894 2070797 Maybridge1_003018 COc1cc([N+](=O)[O-])c2NC(CC(c3ccccc3)c2c1)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B05 compound treatment 790793.0 226000.0 0.32 897229.0 282000.0 0.39 0.5055 0.9948 1469336 Maybridge1_003019 Cn1nccc1c2ccc(Oc3cccc(Cl)c3C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B06 compound treatment 777560.0 212000.0 0.3 879695.0 265000.0 0.37 0.4749 0.995 1005561 Maybridge1_003020 Cc1cccc(NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B07 compound treatment 944581.0 379000.0 0.54 1101477.0 487000.0 0.68 0.8616 0.9935 2070798 Maybridge1_003021 CC1=C(C#N)S(=O)(=O)C(C#N)C(C1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B08 compound treatment 810120.0 245000.0 0.35 974388.0 360000.0 0.5 0.601 0.9841 1083105 Maybridge1_003022 O=C(CC#N)NCc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B09 compound treatment 855147.0 290000.0 0.41 968202.0 353000.0 0.49 0.6402 0.9961 2070799 Maybridge1_003023 CC(=O)c1ccc(o1)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B10 compound treatment 816305.0 251000.0 0.36 965868.0 351000.0 0.49 0.5989 0.988 1083112 Maybridge1_003024 Cc1ccc(cc1C)C(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B11 compound treatment 809923.0 245000.0 0.35 968231.0 354000.0 0.49 0.5948 0.9855 1717233 Maybridge1_003025 COc1cccc(OC)c1C(=O)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B12 compound treatment 797714.0 233000.0 0.33 933359.0 319000.0 0.44 0.5481 0.9894 2070800 Maybridge1_003026 Cc1ccc(cc1)c2nc3cc(C)c(C)cc3nc2c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B13 compound treatment 848811.0 284000.0 0.4 997487.0 383000.0 0.53 0.6627 0.9905 1210739 Maybridge1_003027 CC1(C)OC(=O)C(=C2CCCN2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B14 compound treatment 845702.0 281000.0 0.4 978841.0 364000.0 0.51 0.6412 0.9929 1571466 Maybridge1_003028 Clc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B15 compound treatment 908148.0 343000.0 0.49 926277.0 312000.0 0.43 0.6522 0.9983 2070801 Maybridge1_003029 [O-][N+](=O)c1cc(/C=N/N2CCOCC2)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B16 compound treatment 807910.0 243000.0 0.35 968105.0 353000.0 0.49 0.5926 0.9848 2070802 Maybridge1_003030 CC(C)(NC(=O)Nc1ccccc1)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B17 compound treatment 847216.0 282000.0 0.4 1025083.0 410000.0 0.57 0.6883 0.9849 1384934 Maybridge1_003031 Cc1cc(SCCS(=O)(=O)CCSc2cc(C)c(Cl)cc2C)c(C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B18 compound treatment 808424.0 243000.0 0.35 938257.0 324000.0 0.45 0.5637 0.9914 1244752 Maybridge1_003032 CC(C)c1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B19 compound treatment 834368.0 269000.0 0.38 980372.0 366000.0 0.51 0.6313 0.99 2070803 Maybridge1_003033 CC(C)NC(=O)N1CCc2sccc2C1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B20 compound treatment 825572.0 260000.0 0.37 934968.0 320000.0 0.45 0.5777 0.9957 1206974 Maybridge1_003034 COc1ccc(cc1)n2c(csc2=N)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B21 compound treatment 822016.0 257000.0 0.37 974249.0 360000.0 0.5 0.6129 0.9879 1696004 Maybridge1_003035 OC(=O)C1CN(Cc2ccco2)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B22 compound treatment 808885.0 244000.0 0.35 942561.0 328000.0 0.46 0.5684 0.9907 1406609 Maybridge1_003036 CC1CC(CC(C)(C)C1)NC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B23 mock treatment 837633.0 273000.0 0.39 935413.0 321000.0 0.45 0.5903 0.9974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 B24 mock treatment 140282.0 -425000.0 -0.6 170352.0 -444000.0 -0.62 -0.8655 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C01 compound treatment 691923.0 127000.0 0.18 780098.0 165000.0 0.23 0.2906 0.9926 1943772 Maybridge1_003037 Clc1ccc(CSc2nsc(SCc3ccc(Cl)cc3)n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C02 compound treatment 691615.0 126000.0 0.18 781399.0 167000.0 0.23 0.2916 0.992 2070804 Maybridge1_003038 Cc1cc(OS(=O)(=O)CS(=O)(=O)Oc2ccc(Cl)c(C)c2)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C03 compound treatment 722428.0 157000.0 0.22 859379.0 245000.0 0.34 0.3994 0.979 1679950 Maybridge1_003039 Clc1ccc(Oc2ccccc2S(=O)(=O)N3CCCCC3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C04 compound treatment 717378.0 152000.0 0.22 826130.0 211000.0 0.29 0.3616 0.9885 2070805 Maybridge1_003040 CN(C)/C=C(\C#N)/S(=O)(=O)\C(=C\N(C)C)\C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C05 compound treatment 726975.0 162000.0 0.23 846519.0 232000.0 0.32 0.3913 0.9861 2070806 Maybridge1_003041 Cc1onc(c1C(=O)OCC(F)(F)F)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C06 compound treatment 687415.0 122000.0 0.17 817147.0 202000.0 0.28 0.3226 0.9729 2070807 Maybridge1_003042 CC(=O)OCC(=O)c1cc(Cl)sc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C07 compound treatment 752199.0 187000.0 0.27 872265.0 258000.0 0.36 0.4421 0.9891 2070808 Maybridge1_003043 Cc1onc(c1C(=O)c2ccccc2)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C08 compound treatment 732768.0 168000.0 0.24 873086.0 258000.0 0.36 0.4234 0.9799 2070809 Maybridge1_003044 CC(=O)C(=NNc1c(C)nn(C)c1C)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C09 compound treatment 758903.0 194000.0 0.28 904440.0 290000.0 0.4 0.4806 0.9826 2070810 Maybridge1_003045 CC(=O)c1ccccc1OC(=O)c2ccc(o2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C10 compound treatment 783389.0 218000.0 0.31 856247.0 242000.0 0.34 0.4577 0.9992 2070811 Maybridge1_003046 CC1=C(OS(=O)(=O)c2cc(C)c(Cl)cc2Cl)C(=O)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C11 compound treatment 823734.0 259000.0 0.37 867916.0 253000.0 0.35 0.5097 0.9998 2070812 Maybridge1_003047 Cc1nn(C(=O)c2c(Cl)cccc2Cl)c(C)c1Cc3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C12 compound treatment 774666.0 210000.0 0.3 880330.0 266000.0 0.37 0.4726 0.9942 1659368 Maybridge1_003048 Nc1nnc(SCc2c(Cl)cccc2Cl)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C13 compound treatment 816395.0 251000.0 0.36 926633.0 312000.0 0.44 0.5603 0.9952 2070813 Maybridge1_003049 Cc1cc(NN=Nc2cc(C)on2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C14 compound treatment 811870.0 247000.0 0.35 907927.0 293000.0 0.41 0.5373 0.9971 2070814 Maybridge1_003050 CC(=O)c1nnn(c1C)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C15 compound treatment 860705.0 296000.0 0.42 931541.0 317000.0 0.44 0.6097 0.9997 2070815 Maybridge1_003051 Clc1ccc(cc1)c2noc(n2)c3c[nH]nc3c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C16 compound treatment 799965.0 235000.0 0.33 887367.0 273000.0 0.38 0.505 0.9979 2070816 Maybridge1_003052 Fc1c(COC(=O)Nc2ccccc2)cccc1COC(=O)Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C17 compound treatment 842479.0 277000.0 0.39 906027.0 291000.0 0.41 0.5662 0.9999 1381264 Maybridge1_003053 CN(C(=O)Nc1ccccc1)n2cnc3ccccc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C18 compound treatment 766761.0 202000.0 0.29 846860.0 232000.0 0.32 0.4317 0.9982 2070817 Maybridge1_003054 CS(=O)(=O)CS(=O)(=O)Oc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C19 compound treatment 803426.0 238000.0 0.34 881141.0 266000.0 0.37 0.5024 0.9989 2070818 Maybridge1_003055 Clc1cc(c(Cl)s1)S(=O)(=O)NC(=N)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C20 compound treatment 811666.0 247000.0 0.35 866535.0 252000.0 0.35 0.4962 1.0 2070819 Maybridge1_003056 Cn1cccc1C(=O)N/N=C/c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C21 compound treatment 816492.0 251000.0 0.36 858836.0 244000.0 0.34 0.4935 0.9997 2070820 Maybridge1_003057 CN(C)/C=C/c1nn(C)c(C)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C22 compound treatment 778005.0 213000.0 0.3 832248.0 218000.0 0.3 0.4286 1.0 2070821 Maybridge1_003058 CN(C)CCCN(S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C23 mock treatment 811973.0 247000.0 0.35 885148.0 270000.0 0.38 0.5149 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 C24 mock treatment 136405.0 -429000.0 -0.61 172992.0 -442000.0 -0.62 -0.8668 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D01 compound treatment 763892.0 199000.0 0.28 860023.0 245000.0 0.34 0.4418 0.9955 2070822 Maybridge1_003059 Clc1ccc(cc1Cl)C2CC(=O)CC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D02 compound treatment 739333.0 174000.0 0.25 883609.0 269000.0 0.38 0.4403 0.9797 2070823 Maybridge1_003060 O=C(CC#N)NN=C1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D03 compound treatment 761104.0 196000.0 0.28 938786.0 324000.0 0.45 0.5166 0.973 2070824 Maybridge1_003061 FC(F)(F)COc1cccc(Cl)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D04 compound treatment 801898.0 237000.0 0.34 949046.0 334000.0 0.47 0.5678 0.9872 1183271 Maybridge1_003062 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D05 compound treatment 824820.0 260000.0 0.37 905823.0 291000.0 0.41 0.5482 0.9989 1686627 Maybridge1_003063 Nc1nccc(n1)c2ccc(Oc3cccc(Cl)c3C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D06 compound treatment 854458.0 289000.0 0.41 954243.0 340000.0 0.47 0.6258 0.9975 1214473 Maybridge1_003064 Cc1ccc(NC(=S)C(C#N)C(=O)Nc2ccccc2C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D07 compound treatment 838018.0 273000.0 0.39 1001470.0 387000.0 0.54 0.6558 0.9869 1394780 Maybridge1_003065 COc1ccc(cc1)C2CC(=C(C#N)S(=O)(=O)C2C#N)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D08 compound treatment 864836.0 300000.0 0.43 972885.0 358000.0 0.5 0.6546 0.9969 1580315 Maybridge1_003066 Cc1ccc(NC(=S)C(C#N)C(=O)N2CCCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D09 compound treatment 934832.0 370000.0 0.53 1021537.0 407000.0 0.57 0.773 0.9993 2070825 Maybridge1_003067 Nc1nn(cc1C#N)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D10 compound treatment 861157.0 296000.0 0.42 926437.0 312000.0 0.43 0.6051 0.9999 1472381 Maybridge1_003068 Cc1ccc(cc1C)c2nn(c3ccccc3)c(=O)c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D11 compound treatment 878088.0 313000.0 0.45 991160.0 376000.0 0.53 0.6859 0.9966 1571233 Maybridge1_003069 COC(OC)C(C)(O)c1c(OC)cccc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D12 compound treatment 861349.0 296000.0 0.42 934787.0 320000.0 0.45 0.6135 0.9996 2070826 Maybridge1_003070 CCc1nn2cc(nc2s1)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D13 compound treatment 862618.0 297000.0 0.42 915666.0 301000.0 0.42 0.5959 1.0 2070827 Maybridge1_003071 Cc1nn(C)c(O)c1N=Nc2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D14 compound treatment 876774.0 312000.0 0.44 961770.0 347000.0 0.48 0.6556 0.999 1486629 Maybridge1_003072 COc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D15 compound treatment 938713.0 374000.0 0.53 1009037.0 394000.0 0.55 0.7645 0.9999 2070828 Maybridge1_003073 [O-][N+](=O)c1cc(/C=N/Nc2ccccn2)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D16 compound treatment 943270.0 378000.0 0.54 965425.0 351000.0 0.49 0.7261 0.9989 1162448 Maybridge1_003074 O=C1Nc2ccccc2N=C(c3ccccc3)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D17 compound treatment 996900.0 432000.0 0.61 988785.0 374000.0 0.52 0.8031 0.9967 1573828 Maybridge1_003075 O=S1(=O)CCN(Cc2cccs2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D18 compound treatment 879818.0 315000.0 0.45 941854.0 327000.0 0.46 0.639 1.0 1247208 Maybridge1_003076 CC(=O)Nc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D19 compound treatment 892675.0 328000.0 0.47 977494.0 363000.0 0.51 0.6871 0.9991 2070829 Maybridge1_003077 FC(F)(F)c1cccc(/N=C/c2ccc(Cl)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D20 compound treatment 920564.0 355000.0 0.51 975538.0 361000.0 0.5 0.7132 1.0 1698556 Maybridge1_003078 Clc1cccc(c1Cl)n2c(csc2=N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D21 compound treatment 903492.0 338000.0 0.48 966401.0 352000.0 0.49 0.6871 1.0 2070830 Maybridge1_003079 FC(F)(F)c1cc(NC2=C(C(=O)c3ccccc23)c4ccccc4)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D22 compound treatment 884255.0 319000.0 0.45 949085.0 334000.0 0.47 0.6506 0.9999 2070831 Maybridge1_003080 Cc1ccc(CS/C(=N/N)/N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D23 mock treatment 926393.0 361000.0 0.51 971348.0 357000.0 0.5 0.715 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 D24 mock treatment 135682.0 -429000.0 -0.61 159759.0 -455000.0 -0.63 -0.8805 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E01 compound treatment 765856.0 201000.0 0.29 894728.0 280000.0 0.39 0.478 0.9881 2070832 Maybridge1_003081 CC(C)(C)c1csc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E02 compound treatment 764333.0 199000.0 0.28 933938.0 319000.0 0.45 0.5151 0.9762 2070833 Maybridge1_003082 Clc1ccc(cc1)C2CC(=O)CC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E03 compound treatment 820752.0 256000.0 0.36 970440.0 356000.0 0.5 0.6078 0.9883 2070834 Maybridge1_003083 CC(C)(C)c1csc(=S)n1CCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E04 compound treatment 846941.0 282000.0 0.4 993556.0 379000.0 0.53 0.657 0.9907 1080296 Maybridge1_003084 CC1SCC(=NO)CS1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E05 compound treatment 843501.0 278000.0 0.4 1035771.0 421000.0 0.59 0.6952 0.9816 2070835 Maybridge1_003085 Cc1cc(C)n(n1)C2=NCCN2C(=O)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E06 compound treatment 858158.0 293000.0 0.42 1031005.0 416000.0 0.58 0.7052 0.9868 2070836 Maybridge1_003086 CSC(=N)n1nc(SC)nc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E07 compound treatment 886033.0 321000.0 0.46 1006502.0 392000.0 0.55 0.7091 0.996 1349717 Maybridge1_003087 Cc1onc(c1C(O)c2ccccc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E08 compound treatment 888381.0 323000.0 0.46 1014838.0 400000.0 0.56 0.7196 0.9954 1322001 Maybridge1_003088 Cc1nn(C)c(C)c1NC(=O)c2ccccc2NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E09 compound treatment 922631.0 357000.0 0.51 1026707.0 412000.0 0.57 0.7658 0.9981 1387444 Maybridge1_003089 Fc1ccc(cc1)C(=O)CCCC(=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E10 compound treatment 881623.0 316000.0 0.45 936019.0 321000.0 0.45 0.6351 1.0 2070837 Maybridge1_003090 CCOC(=O)c1cnn(c1c2ccccc2)c3c(Cl)cc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E11 compound treatment 908218.0 343000.0 0.49 1004972.0 390000.0 0.54 0.7299 0.9985 2070838 Maybridge1_003091 Cc1nn(c(C)c1Cc2c(Cl)cccc2Cl)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E12 compound treatment 930455.0 365000.0 0.52 1100936.0 486000.0 0.68 0.8469 0.9913 2070839 Maybridge1_003092 CN(C)c1c(/C=C/2\C(=O)Nc3ccccc23)cc(\C=C/4\C(=O)Nc5ccccc45)c(N(C)C)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E13 compound treatment 853387.0 288000.0 0.41 972796.0 358000.0 0.5 0.643 0.9952 1073411 Maybridge1_003093 NC1=C(C(=O)c2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E14 compound treatment 920932.0 356000.0 0.51 1008742.0 394000.0 0.55 0.7464 0.9991 2070840 Maybridge1_003094 CC(=O)c1nnn(c1C)c2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E15 compound treatment 949935.0 385000.0 0.55 1039339.0 425000.0 0.59 0.8057 0.9992 1552363 Maybridge1_003095 O=S(=O)(CS(=O)(=O)N1CCOCC1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E16 compound treatment 938924.0 374000.0 0.53 1003354.0 389000.0 0.54 0.7591 1.0 1720964 Maybridge1_003096 O=S(=O)(NCC#C)c1ccc(C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E17 compound treatment 960384.0 395000.0 0.56 1030476.0 416000.0 0.58 0.8075 0.9999 2070841 Maybridge1_003097 Clc1cc(c(Cl)s1)S(=O)(=O)NCCCNS(=O)(=O)c2cc(Cl)sc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E18 compound treatment 931137.0 366000.0 0.52 997003.0 382000.0 0.53 0.745 0.9999 2070842 Maybridge1_003098 Fc1ccc(c2ccc(CNC(=O)c3ccc(Cl)cc3)o2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E19 compound treatment 939062.0 374000.0 0.53 949961.0 335000.0 0.47 0.7066 0.9979 2070843 Maybridge1_003099 Cc1nn(C)c(C)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E20 compound treatment 943972.0 379000.0 0.54 1025061.0 410000.0 0.57 0.7856 0.9995 2070844 Maybridge1_003100 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E21 compound treatment 909928.0 345000.0 0.49 1009100.0 394000.0 0.55 0.7356 0.9984 2070845 Maybridge1_003101 Cc1c([N+](=O)[O-])c(C/C=N/O)nn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E22 compound treatment 886699.0 322000.0 0.46 990885.0 376000.0 0.52 0.6943 0.9977 2070846 Maybridge1_003102 COc1ccc(OCC(F)(F)F)c(c1)C(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E23 mock treatment 916431.0 351000.0 0.5 1029202.0 414000.0 0.58 0.762 0.9974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 E24 mock treatment 151901.0 -413000.0 -0.59 156333.0 -458000.0 -0.64 -0.8676 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F01 compound treatment 768923.0 204000.0 0.29 856930.0 242000.0 0.34 0.4438 0.9971 2070847 Maybridge1_003103 O=C1CC(CC(=O)C1)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F02 compound treatment 786453.0 221000.0 0.31 877490.0 263000.0 0.37 0.4817 0.9971 2070848 Maybridge1_003104 CC(C)C/1CCC(C)C\C1=N/NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F03 compound treatment 824529.0 259000.0 0.37 985354.0 371000.0 0.52 0.6264 0.9863 2070849 Maybridge1_003105 CC1(C)OC(=O)C(CC#C)(CC#C)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F04 compound treatment 807114.0 242000.0 0.34 968455.0 354000.0 0.49 0.5922 0.9845 1413077 Maybridge1_003106 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F05 compound treatment 862973.0 298000.0 0.42 934932.0 320000.0 0.45 0.6153 0.9996 2070850 Maybridge1_003107 CC(NC=C(C#N)C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F06 compound treatment 846132.0 281000.0 0.4 1008078.0 393000.0 0.55 0.6705 0.9879 1183062 Maybridge1_003108 Cc1ccc(NC(=S)C(C#N)C(=O)N2CCOCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F07 compound treatment 882018.0 317000.0 0.45 980581.0 366000.0 0.51 0.6795 0.9981 1504515 Maybridge1_003109 Clc1ccc(Oc2cccc(Cl)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F08 compound treatment 872849.0 308000.0 0.44 992392.0 378000.0 0.53 0.6819 0.9958 1083106 Maybridge1_003110 CC1CC(CC(C)(C)C1)NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F09 compound treatment 930366.0 365000.0 0.52 1044590.0 430000.0 0.6 0.7912 0.9974 1521482 Maybridge1_003111 Nc1nn(cc1c2nnn[nH]2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F10 compound treatment 913916.0 349000.0 0.5 930159.0 315000.0 0.44 0.6618 0.9982 1058518 Maybridge1_003112 OC(=O)c1ccccc1C(=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F11 compound treatment 929496.0 364000.0 0.52 983858.0 369000.0 0.51 0.7304 1.0 2070851 Maybridge1_003113 CC(=O)OC(C(OC(=O)C)C(=O)Nc1ccc(Cl)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F12 compound treatment 967853.0 403000.0 0.57 1006733.0 392000.0 0.55 0.7916 0.9997 2070852 Maybridge1_003114 Cn1c2CCCCc2c3CCCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F13 compound treatment 929272.0 364000.0 0.52 873615.0 259000.0 0.36 0.6215 0.9845 2070853 Maybridge1_003115 Cc1nn(C)c(O)c1N=Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F14 compound treatment 919810.0 355000.0 0.5 962000.0 347000.0 0.48 0.6991 0.9998 2070854 Maybridge1_003116 [O-][N+](=O)c1ccc(cc1)C(=O)CSC2=NCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F15 compound treatment 1060701.0 496000.0 0.7 1122240.0 508000.0 0.71 0.9988 1.0 2070855 Maybridge1_003117 [O-][N+](=O)c1cc(C#N)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F16 compound treatment 926304.0 361000.0 0.51 968911.0 354000.0 0.49 0.7125 0.9998 1264193 Maybridge1_003118 CC1CN=C(c2ccccc2)c3ccccc3C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F17 compound treatment 961550.0 396000.0 0.56 1017286.0 403000.0 0.56 0.7956 1.0 2070856 Maybridge1_003119 O=C1NCCCCC1N2CCS(=O)(=O)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F18 compound treatment 955593.0 390000.0 0.56 1010970.0 396000.0 0.55 0.7834 1.0 1181207 Maybridge1_003120 O=c1n(c(nc2ccccc12)c3ccccc3)C4(CCCCC4)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F19 compound treatment 977652.0 413000.0 0.59 982847.0 368000.0 0.51 0.7779 0.9978 2070857 Maybridge1_003121 FC(F)(F)c1ccc(cc1)C(=O)NC(=O)Nc2ccc(cc2)c3cnco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F20 compound treatment 934805.0 370000.0 0.53 971897.0 357000.0 0.5 0.724 0.9996 2070858 Maybridge1_003122 Clc1ccc(cc1)c2csc(=N)n2c3cc(Cl)c(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F21 compound treatment 1003531.0 438000.0 0.62 1012507.0 398000.0 0.55 0.8331 0.9983 1562587 Maybridge1_003123 CC(=O)N1C=CC(C=C1)c2c[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F22 compound treatment 896171.0 331000.0 0.47 985717.0 371000.0 0.52 0.6987 0.9989 2070859 Maybridge1_003124 COc1ccc(CS/C(=N/N)/N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F23 mock treatment 936292.0 371000.0 0.53 982857.0 368000.0 0.51 0.7363 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 F24 mock treatment 146883.0 -418000.0 -0.59 148213.0 -467000.0 -0.65 -0.8807 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G01 compound treatment 733492.0 168000.0 0.24 841122.0 226000.0 0.32 0.3926 0.9907 2070860 Maybridge1_003125 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1NCCc2ccc(Cl)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G02 compound treatment 754367.0 189000.0 0.27 889247.0 275000.0 0.38 0.461 0.9851 1222526 Maybridge1_003126 CN(C1CC2CC1C=C2)C(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G03 compound treatment 788417.0 223000.0 0.32 974064.0 359000.0 0.5 0.5789 0.9758 2070861 Maybridge1_003127 Clc1ccc(Oc2ccccc2N/N=C(\C#N)/C(=O)N3CCCC3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G04 compound treatment 796521.0 231000.0 0.33 959276.0 345000.0 0.48 0.5725 0.9829 2070862 Maybridge1_003128 CC(=O)N1CCC(CC1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G05 compound treatment 812991.0 248000.0 0.35 983818.0 369000.0 0.51 0.6132 0.9829 2070863 Maybridge1_003129 [O-][N+](=O)c1ccc(Sc2nc[nH]n2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G06 compound treatment 800715.0 236000.0 0.34 908474.0 294000.0 0.41 0.5266 0.995 1701114 Maybridge1_003130 COC(CNc1cccc(F)c1C#N)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G07 compound treatment 842882.0 278000.0 0.39 986683.0 372000.0 0.52 0.6461 0.9909 2070864 Maybridge1_003131 COC(=O)c1sccc1NC(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G08 compound treatment 833080.0 268000.0 0.38 950711.0 336000.0 0.47 0.6008 0.9947 2070865 Maybridge1_003132 CCOC(=O)c1cnn(c1C)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G09 compound treatment 862102.0 297000.0 0.42 982187.0 367000.0 0.51 0.661 0.9954 2070866 Maybridge1_003133 O=C(Oc1ccccc1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G10 compound treatment 864557.0 299000.0 0.43 940991.0 326000.0 0.46 0.6229 0.9994 1177640 Maybridge1_003134 CCOC(=O)c1cnc(Nc2nc(cs2)C(C)(C)C)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G11 compound treatment 845578.0 280000.0 0.4 944396.0 330000.0 0.46 0.6071 0.9975 2070867 Maybridge1_003135 Fc1c(CSC2=NCCN2)cccc1CSC3=NCCN3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G12 compound treatment 859187.0 294000.0 0.42 992506.0 378000.0 0.53 0.6683 0.9934 2070868 Maybridge1_003136 CC(=O)CC(=O)c1c(C)nn(c1O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G13 compound treatment 912948.0 348000.0 0.49 1001917.0 387000.0 0.54 0.7316 0.999 2070869 Maybridge1_003137 CN(C)/C=C(\C#N)/C(=O)Nc1cc(C)on1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G14 compound treatment 882558.0 317000.0 0.45 917345.0 303000.0 0.42 0.6176 0.9994 1652979 Maybridge1_003138 NC(=O)c1cccc(C(=O)N)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G15 compound treatment 925230.0 360000.0 0.51 980940.0 366000.0 0.51 0.7233 1.0 2070870 Maybridge1_003139 Clc1cccc(Cl)c1CC(Cc2c(Cl)cccc2Cl)(C#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G16 compound treatment 909243.0 344000.0 0.49 970996.0 356000.0 0.5 0.6974 1.0 2070871 Maybridge1_003140 Cc1c(C)c(C)c(C(=O)C2CCN(CC2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G17 compound treatment 925549.0 360000.0 0.51 968739.0 354000.0 0.49 0.7115 0.9998 2070872 Maybridge1_003141 CC(O)c1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G18 compound treatment 866940.0 302000.0 0.43 994817.0 380000.0 0.53 0.6783 0.9945 2070873 Maybridge1_003142 Cc1cccc(C(=O)O)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G19 compound treatment 918375.0 353000.0 0.5 993372.0 379000.0 0.53 0.7286 0.9997 1353717 Maybridge1_003143 OCCCc1cc(n[nH]1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G20 compound treatment 907363.0 342000.0 0.49 994058.0 379000.0 0.53 0.7182 0.9991 1487603 Maybridge1_003144 Clc1ccc(NS(=O)(=O)CC(=O)CS(=O)(=O)Nc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G21 compound treatment 859731.0 295000.0 0.42 990123.0 375000.0 0.52 0.6665 0.9939 2070874 Maybridge1_003145 Cc1cn(nc1c2ccccc2)C(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G22 compound treatment 855596.0 290000.0 0.41 973169.0 358000.0 0.5 0.6456 0.9955 2070875 Maybridge1_003146 CCOC(=O)C(/C=N/c1ccc(Cl)cc1Cl)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G23 mock treatment 876159.0 311000.0 0.44 1012125.0 397000.0 0.55 0.7047 0.9937 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 G24 mock treatment 152383.0 -413000.0 -0.59 156312.0 -458000.0 -0.64 -0.8671 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H01 compound treatment 765291.0 200000.0 0.28 848385.0 234000.0 0.33 0.4317 0.9977 2070876 Maybridge1_003147 CC12CCC(=O)NC2=CC(=O)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H02 compound treatment 758206.0 193000.0 0.27 859594.0 245000.0 0.34 0.4356 0.9941 1018434 Maybridge1_003148 O=C(CC#N)N1CCOCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H03 compound treatment 825976.0 261000.0 0.37 932764.0 318000.0 0.44 0.5759 0.996 2070877 Maybridge1_003149 COc1cccc(CNC(=S)SCC(=O)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H04 compound treatment 815602.0 250000.0 0.36 920310.0 306000.0 0.43 0.5532 0.996 2070878 Maybridge1_003150 CC1CCCN(C1)S(=O)(=O)c2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H05 compound treatment 840440.0 275000.0 0.39 973365.0 359000.0 0.5 0.6305 0.9927 1494113 Maybridge1_003151 Nc1oncc1c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H06 compound treatment 853688.0 289000.0 0.41 966400.0 352000.0 0.49 0.637 0.9961 1370912 Maybridge1_003152 Clc1ccccc1NC(=S)C(C#N)C(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H07 compound treatment 903805.0 339000.0 0.48 984873.0 370000.0 0.52 0.7056 0.9994 1262194 Maybridge1_003153 CNn1cnc2ccsc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H08 compound treatment 899428.0 334000.0 0.48 996993.0 382000.0 0.53 0.7131 0.9984 1083104 Maybridge1_003154 O=C(CC#N)NCCc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H09 compound treatment 899854.0 335000.0 0.48 990021.0 375000.0 0.52 0.7067 0.9989 1311727 Maybridge1_003155 Clc1cccc(N2CCC(CC2)C#N)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H10 compound treatment 869039.0 304000.0 0.43 935640.0 321000.0 0.45 0.6221 0.9998 1742190 Maybridge1_003156 Fc1ccc(cc1)c2nn(c3ccccc3)c(=O)c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H11 compound treatment 909269.0 344000.0 0.49 949710.0 335000.0 0.47 0.6764 0.9997 1029322 Maybridge1_003157 CC(=O)c1ccc(Oc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H12 compound treatment 881696.0 317000.0 0.45 927078.0 312000.0 0.44 0.6264 0.9999 1055233 Maybridge1_003158 O=c1onc(c2ccccc2)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H13 compound treatment 933847.0 369000.0 0.52 909175.0 294000.0 0.41 0.6611 0.9927 1074389 Maybridge1_003159 CC(=O)c1ccc(Sc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H14 compound treatment 919696.0 355000.0 0.5 931002.0 316000.0 0.44 0.6684 0.9978 1929006 Maybridge1_003160 Brc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H15 compound treatment 945784.0 381000.0 0.54 964026.0 349000.0 0.49 0.7272 0.9986 1534999 Maybridge1_003161 C=CCN1CCS(=O)(=O)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H16 compound treatment 928897.0 364000.0 0.52 998911.0 384000.0 0.54 0.7447 0.9998 2070879 Maybridge1_003162 O=C(NCCCCCCNC(=O)NC1(CCCCC1)C#C)NC2(CCCCC2)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H17 compound treatment 957887.0 393000.0 0.56 973926.0 359000.0 0.5 0.7492 0.9985 2070880 Maybridge1_003163 CC(C)c1ccc(NC(=S)N/N=C(\C)/c2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H18 compound treatment 890830.0 326000.0 0.46 942342.0 328000.0 0.46 0.6506 1.0 1202690 Maybridge1_003164 Cc1c(C)c(C)c(C(=O)CCC(=O)O)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H19 compound treatment 959257.0 394000.0 0.56 953225.0 338000.0 0.47 0.7301 0.9964 2070881 Maybridge1_003165 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H20 compound treatment 834362.0 269000.0 0.38 966904.0 352000.0 0.49 0.618 0.9924 1171356 Maybridge1_003166 CC(C)c1ccc(NC(=O)c2ccccc2N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H21 compound treatment 929971.0 365000.0 0.52 926181.0 311000.0 0.43 0.674 0.9961 1330601 Maybridge1_003167 CCOC(=O)c1c(N)c(sc1Nc2ccccc2OC)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H22 compound treatment 879737.0 315000.0 0.45 933875.0 319000.0 0.45 0.6311 1.0 2070882 Maybridge1_003168 COc1cc(I)c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H23 mock treatment 908346.0 343000.0 0.49 984833.0 370000.0 0.52 0.7101 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 H24 mock treatment 147469.0 -418000.0 -0.59 164453.0 -450000.0 -0.63 -0.8641 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I01 compound treatment 758301.0 193000.0 0.27 865068.0 250000.0 0.35 0.4411 0.993 2070883 Maybridge1_003169 CC(C)(C)c1csc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I02 compound treatment 760924.0 196000.0 0.28 911949.0 297000.0 0.41 0.49 0.9813 2070884 Maybridge1_003170 CCCCNC(=O)N(C)C1CC2CC1C=C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I03 compound treatment 793138.0 228000.0 0.32 967824.0 353000.0 0.49 0.5775 0.9794 2070885 Maybridge1_003171 Clc1ccc(Oc2ccccc2NN=C(C#N)C#N)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I04 compound treatment 811933.0 247000.0 0.35 965125.0 350000.0 0.49 0.5937 0.9868 2070886 Maybridge1_003172 Cc1c(O)c(C#N)sc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I05 compound treatment 817112.0 252000.0 0.36 1002052.0 387000.0 0.54 0.6354 0.9801 2070887 Maybridge1_003173 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc[nH]n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I06 compound treatment 813259.0 248000.0 0.35 984110.0 369000.0 0.52 0.6138 0.983 1437874 Maybridge1_003174 Clc1ccc(cc1)C(=O)C2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I07 compound treatment 863683.0 299000.0 0.42 966342.0 352000.0 0.49 0.647 0.9974 2070888 Maybridge1_003175 Cc1onc(c1C(=O)c2ccc(F)cc2)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I08 compound treatment 871187.0 306000.0 0.44 887245.0 273000.0 0.38 0.5765 0.9977 1265175 Maybridge1_003176 CCOC(=O)c1cnc(N)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I09 compound treatment 870191.0 305000.0 0.43 956909.0 342000.0 0.48 0.6442 0.9989 1708110 Maybridge1_003177 Cc1onc(c1C(=O)Oc2ccccc2)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I10 compound treatment 892617.0 327000.0 0.47 934264.0 320000.0 0.45 0.6444 0.9998 2070889 Maybridge1_003178 CCCc1c(cnn1c2c(Cl)cc(Cl)cc2Cl)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I11 compound treatment 892485.0 327000.0 0.47 970646.0 356000.0 0.5 0.6802 0.9995 2070890 Maybridge1_003179 Clc1cccc(NCCCN2CCCCC2)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I12 compound treatment 835769.0 271000.0 0.38 995944.0 381000.0 0.53 0.6481 0.9874 1604920 Maybridge1_003180 NC(=O)C1CCN(CC1)C(=S)NC2CC3CC2C=C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I13 compound treatment 891925.0 327000.0 0.46 972258.0 358000.0 0.5 0.6812 0.9994 1611997 Maybridge1_003181 Cc1cc(NC(=O)c2ccccc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I14 compound treatment 893915.0 329000.0 0.47 989485.0 375000.0 0.52 0.7002 0.9985 2070891 Maybridge1_003182 Cc1noc(C)c1S(=O)(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I15 compound treatment 957918.0 393000.0 0.56 1024389.0 410000.0 0.57 0.799 0.9999 1451795 Maybridge1_003183 Cc1cccn(Cc2c(F)cccc2Cl)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I16 compound treatment 880112.0 315000.0 0.45 916701.0 302000.0 0.42 0.6145 0.9995 2070892 Maybridge1_003184 O=C(Nc1ccccc1)OC2CCSC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I17 compound treatment 961923.0 397000.0 0.56 1004857.0 390000.0 0.54 0.7837 0.9998 1173925 Maybridge1_003185 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I18 compound treatment 892849.0 328000.0 0.47 980572.0 366000.0 0.51 0.6903 0.999 1703198 Maybridge1_003186 NC(=O)c1cccc2cccc(C(=O)O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I19 compound treatment 932432.0 367000.0 0.52 961530.0 347000.0 0.48 0.7114 0.9993 2070893 Maybridge1_003187 N/C(=N\O)/CSc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I20 compound treatment 910838.0 346000.0 0.49 982067.0 367000.0 0.51 0.7099 0.9998 2070894 Maybridge1_003188 CN(C)/C=C/C(=N)SCc1cc(F)cc2COCOc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I21 compound treatment 933287.0 368000.0 0.52 1053709.0 439000.0 0.61 0.8031 0.997 2070895 Maybridge1_003189 Cc1c[nH]nc1c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I22 compound treatment 879697.0 315000.0 0.45 1004648.0 390000.0 0.54 0.7009 0.9953 2070896 Maybridge1_003190 Clc1ccc(C2CC(=O)CC(=O)C2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I23 mock treatment 909191.0 344000.0 0.49 1019595.0 405000.0 0.56 0.7453 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 I24 mock treatment 148884.0 -416000.0 -0.59 207557.0 -407000.0 -0.57 -0.8201 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J01 compound treatment 760421.0 195000.0 0.28 829815.0 215000.0 0.3 0.4085 0.9993 2070897 Maybridge1_003191 NC(=N)Nc1nc(cs1)c2cc(Cl)sc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J02 compound treatment 783466.0 218000.0 0.31 923982.0 309000.0 0.43 0.5245 0.987 1642787 Maybridge1_003192 COC(=O)c1sc(NCC=C)c(C(=O)OC)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J03 compound treatment 804209.0 239000.0 0.34 957393.0 343000.0 0.48 0.5783 0.9861 2070898 Maybridge1_003193 COc1cc2COC(=O)/C(=C\N(C)C)/c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J04 compound treatment 819122.0 254000.0 0.36 867213.0 252000.0 0.35 0.5044 0.9999 2070899 Maybridge1_003194 CC1CCCN(C1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J05 compound treatment 825191.0 260000.0 0.37 979229.0 364000.0 0.51 0.621 0.9878 2070900 Maybridge1_003195 C(SCc1nnn[nH]1)c2nnn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J06 compound treatment 850943.0 286000.0 0.41 949513.0 335000.0 0.47 0.6176 0.9976 1282320 Maybridge1_003196 COc1ccccc1NC(=S)C(C#N)C(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J07 compound treatment 897771.0 333000.0 0.47 979121.0 364000.0 0.51 0.6939 0.9994 2070901 Maybridge1_003197 Oc1nccn(c2cccc(c2)C(F)(F)F)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J08 compound treatment 846068.0 281000.0 0.4 959858.0 345000.0 0.48 0.6229 0.9957 2070902 Maybridge1_003198 Cc1ccc(CC(=O)c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J09 compound treatment 922270.0 357000.0 0.51 978436.0 364000.0 0.51 0.7178 1.0 2070903 Maybridge1_003199 CC(=O)c1ccc(o1)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J10 compound treatment 884417.0 319000.0 0.45 956445.0 342000.0 0.48 0.6581 0.9997 1006292 Maybridge1_003200 Oc1nnc(c2ccccc2)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J11 compound treatment 915380.0 350000.0 0.5 936147.0 321000.0 0.45 0.6692 0.9986 2070904 Maybridge1_003201 CC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J12 compound treatment 874930.0 310000.0 0.44 905899.0 291000.0 0.41 0.5987 0.9992 1401466 Maybridge1_003202 O=C(Nc1ccccc1C(=O)Nc2ccncc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J13 compound treatment 909775.0 345000.0 0.49 928754.0 314000.0 0.44 0.6563 0.9984 2070905 Maybridge1_003203 Cc1nn(c(O)c1N=Nc2ccc(C)cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J14 compound treatment 923611.0 358000.0 0.51 879793.0 265000.0 0.37 0.6219 0.9875 1730722 Maybridge1_003204 CCOC(=O)c1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J15 compound treatment 932530.0 367000.0 0.52 989961.0 375000.0 0.52 0.7395 1.0 1091121 Maybridge1_003205 O=S1(=O)CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J16 compound treatment 922033.0 357000.0 0.51 987551.0 373000.0 0.52 0.7266 0.9999 1049219 Maybridge1_003206 Nc1sc2CCCc2c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J17 compound treatment 952294.0 387000.0 0.55 984892.0 370000.0 0.52 0.7544 0.9995 2070906 Maybridge1_003207 N#Cc1ccc(cc1)c2cnco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J18 compound treatment 870999.0 306000.0 0.43 961933.0 347000.0 0.48 0.65 0.9986 1087389 Maybridge1_003208 Cn1ncc2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J19 compound treatment 904516.0 339000.0 0.48 968534.0 354000.0 0.49 0.6902 0.9999 1393767 Maybridge1_003209 CCOC(=O)c1cnc2ccc(Cl)cc2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J20 compound treatment 919224.0 354000.0 0.5 980930.0 366000.0 0.51 0.7172 1.0 2070907 Maybridge1_003210 Clc1ccc(CSc2nsc(Nc3ccc(Cl)cc3)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J21 compound treatment 867688.0 303000.0 0.43 1010219.0 395000.0 0.55 0.6943 0.9925 1395752 Maybridge1_003211 CCOC(=O)c1c(N)c(sc1Nc2ccccc2OC)C(=O)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J22 compound treatment 923081.0 358000.0 0.51 973984.0 359000.0 0.5 0.7142 1.0 2070908 Maybridge1_003212 O=C/1/C(=C/c2ccc3OCOc3c2)/CCC\C1=C/c4ccc5OCOc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J23 mock treatment 929568.0 364000.0 0.52 933811.0 319000.0 0.45 0.6811 0.9971 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 J24 mock treatment 140690.0 -424000.0 -0.6 165166.0 -450000.0 -0.63 -0.8702 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K01 compound treatment 746246.0 181000.0 0.26 854467.0 240000.0 0.33 0.4186 0.9917 2070909 Maybridge1_003213 NCCSCc1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K02 compound treatment 747384.0 182000.0 0.26 887115.0 272000.0 0.38 0.4519 0.9826 2070910 Maybridge1_003214 CC(=O)c1nnn(c1C)c2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K03 compound treatment 801246.0 236000.0 0.34 988937.0 374000.0 0.52 0.6065 0.9773 1650150 Maybridge1_003215 OC(=O)c1nnn(c1c2ccccc2)c3ccccc3Oc4ccc(Cl)cc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K04 compound treatment 771330.0 206000.0 0.29 881777.0 267000.0 0.37 0.4707 0.993 2070911 Maybridge1_003216 COC(CN/C(=N\C#N)/SC)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K05 compound treatment 757819.0 193000.0 0.27 983197.0 368000.0 0.51 0.5571 0.9566 1005731 Maybridge1_003217 CCCCCCCCCCCC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K06 compound treatment 827979.0 263000.0 0.37 933739.0 319000.0 0.44 0.5789 0.9962 2070912 Maybridge1_003218 Cc1nn(C)c(C)c1NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K07 compound treatment 844800.0 280000.0 0.4 971661.0 357000.0 0.5 0.6332 0.9938 2070913 Maybridge1_003219 Cc1nn(C)c(O)c1C(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K08 compound treatment 822423.0 257000.0 0.37 864611.0 250000.0 0.35 0.5052 0.9997 2070914 Maybridge1_003220 Cc1cc(C)n(n1)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K09 compound treatment 898807.0 334000.0 0.47 977434.0 363000.0 0.51 0.6932 0.9995 1459994 Maybridge1_003221 Clc1ccc(Oc2ccccc2C#N)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K10 compound treatment 831201.0 266000.0 0.38 945006.0 330000.0 0.46 0.5933 0.9952 2070915 Maybridge1_003222 CCOC(=O)c1cnn(c1COC)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K11 compound treatment 882445.0 317000.0 0.45 964171.0 349000.0 0.49 0.6637 0.9993 2070916 Maybridge1_003223 CSc1cc(cc(SC)c1SC)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K12 compound treatment 828171.0 263000.0 0.37 934769.0 320000.0 0.45 0.5801 0.9961 2070917 Maybridge1_003224 CCCCNC(=O)NS(=O)(=O)c1cc(Cl)sc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K13 compound treatment 886447.0 321000.0 0.46 990977.0 376000.0 0.52 0.6942 0.9976 1108929 Maybridge1_003225 CC(=O)Cc1ncn(n1)c2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K14 compound treatment 838651.0 274000.0 0.39 1009818.0 395000.0 0.55 0.6647 0.9855 2070918 Maybridge1_003226 Fc1c(CC#N)cccc1CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K15 compound treatment 905645.0 341000.0 0.48 1010304.0 396000.0 0.55 0.7325 0.9979 1936403 Maybridge1_003227 CN(C)/C=N/S(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K16 compound treatment 880329.0 315000.0 0.45 873395.0 259000.0 0.36 0.572 0.9942 2070919 Maybridge1_003228 FC(F)(F)c1ccc(CNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K17 compound treatment 886276.0 321000.0 0.46 990885.0 376000.0 0.52 0.6939 0.9976 2070920 Maybridge1_003229 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K18 compound treatment 884936.0 320000.0 0.45 943538.0 329000.0 0.46 0.6459 1.0 2070921 Maybridge1_003230 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1NCCC2CC2(Cl)Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K19 compound treatment 2382842.0 1820000.0 2.58 3319451.0 2700000.0 3.77 4.4952 0.983 2070922 Maybridge1_003231 CN(C)/C=C(\C#N)/c1nc(cs1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K20 compound treatment 878839.0 314000.0 0.45 959276.0 345000.0 0.48 0.6552 0.9993 2070923 Maybridge1_003232 NC(=O)N/1CCCCC\C1=N/O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K21 compound treatment 930043.0 365000.0 0.52 984119.0 369000.0 0.52 0.7312 1.0 1068856 Maybridge1_003233 CC(=O)c1cnn(c1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K22 compound treatment 855662.0 291000.0 0.41 967825.0 353000.0 0.49 0.6404 0.9962 1510203 Maybridge1_003234 CN(C)c1ccc(cc1)C2CC(=O)CC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K23 mock treatment 902993.0 338000.0 0.48 997674.0 383000.0 0.53 0.7174 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 K24 mock treatment 137914.0 -427000.0 -0.61 164495.0 -450000.0 -0.63 -0.8736 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L01 compound treatment 754957.0 190000.0 0.27 835191.0 220000.0 0.31 0.4083 0.9979 2070924 Maybridge1_003235 CCOC(=O)CC1NCCNC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L02 compound treatment 766743.0 202000.0 0.29 881454.0 267000.0 0.37 0.4658 0.9917 2070925 Maybridge1_003236 COc1cccc(/C=N/NC(=O)CC#N)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L03 compound treatment 800316.0 235000.0 0.33 937219.0 322000.0 0.45 0.5545 0.9894 2070926 Maybridge1_003237 FC(F)(F)c1ccc(cc1)C2CC(=CC(=O)C2)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L04 compound treatment 794660.0 230000.0 0.33 899201.0 284000.0 0.4 0.5114 0.9953 2070927 Maybridge1_003238 CC1CCN(CC1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L05 compound treatment 835480.0 270000.0 0.38 948440.0 334000.0 0.47 0.601 0.9955 1517662 Maybridge1_003239 Clc1ccc(cc1)C2CC(=O)C=C(C2)NCc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L06 compound treatment 790075.0 225000.0 0.32 909348.0 295000.0 0.41 0.5167 0.9923 1557130 Maybridge1_003240 COc1ccccc1NC(=S)C(C#N)C(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L07 compound treatment 928156.0 363000.0 0.52 1012900.0 398000.0 0.56 0.7577 0.9993 2070928 Maybridge1_003241 CC1=C(C#N)S(=O)(=O)C(C#N)C(C1)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L08 compound treatment 761044.0 196000.0 0.28 936964.0 322000.0 0.45 0.5148 0.9736 2070929 Maybridge1_003242 Clc1ccc(/N=C\2/C(=O)Nc3ccc(Br)cc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L09 compound treatment 874858.0 310000.0 0.44 928638.0 314000.0 0.44 0.621 1.0 2070930 Maybridge1_003243 CC(=O)c1ccc(o1)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L10 compound treatment 835047.0 270000.0 0.38 945701.0 331000.0 0.46 0.5978 0.9958 1205536 Maybridge1_003244 Fc1ccc(cc1)c2n[nH]c(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L11 compound treatment 869448.0 304000.0 0.43 941872.0 327000.0 0.46 0.6286 0.9997 2070931 Maybridge1_003245 COc1ccc(Oc2ccc(cc2)C(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L12 compound treatment 884336.0 319000.0 0.45 943639.0 329000.0 0.46 0.6454 1.0 1517312 Maybridge1_003246 O=C(Nc1nccs1)c2ccccc2NC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L13 compound treatment 796364.0 231000.0 0.33 864743.0 250000.0 0.35 0.4791 0.9996 1386165 Maybridge1_003247 CSc1cc(n[nH]1)c2ccc(Oc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L14 compound treatment 874366.0 309000.0 0.44 900309.0 286000.0 0.4 0.5926 0.9988 2070932 Maybridge1_003248 COc1cc(/C=N/NC(=S)N\N=C\c2ccc(O)c(OC)c2)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L15 compound treatment 899763.0 335000.0 0.48 980641.0 366000.0 0.51 0.6974 0.9994 2070933 Maybridge1_003249 OC(=O)c1csc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L16 compound treatment 828911.0 264000.0 0.38 965356.0 351000.0 0.49 0.611 0.9914 1453213 Maybridge1_003250 Nc1sc2CCCCCc2c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L17 compound treatment 942011.0 377000.0 0.54 966100.0 351000.0 0.49 0.7255 0.999 2070934 Maybridge1_003251 [O-][N+](=O)c1ccccc1c2cnco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L18 compound treatment 881286.0 316000.0 0.45 877728.0 263000.0 0.37 0.5773 0.9949 1026020 Maybridge1_003252 O=c1n(ncc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L19 compound treatment 910761.0 346000.0 0.49 951197.0 336000.0 0.47 0.6794 0.9997 2070935 Maybridge1_003253 COC(=O)c1cccc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L20 compound treatment 884320.0 319000.0 0.45 935068.0 320000.0 0.45 0.6369 1.0 1569306 Maybridge1_003254 Cc1ccc(NC(=O)c2ccccc2N)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L21 compound treatment 894395.0 329000.0 0.47 974232.0 360000.0 0.5 0.6856 0.9994 2070936 Maybridge1_003255 COc1ccc(/C=N/NC(=O)CC#N)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L22 compound treatment 860489.0 295000.0 0.42 894569.0 280000.0 0.39 0.573 0.9993 2070937 Maybridge1_003256 Clc1ccc(/C=C/2\CCC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L23 mock treatment 887873.0 323000.0 0.46 962970.0 348000.0 0.49 0.668 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 L24 mock treatment 139800.0 -425000.0 -0.6 157014.0 -458000.0 -0.64 -0.8791 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M01 compound treatment 735991.0 171000.0 0.24 844660.0 230000.0 0.32 0.3986 0.9906 2070938 Maybridge1_003257 NC(CSCc1c(F)cccc1Cl)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M02 compound treatment 715667.0 151000.0 0.21 895897.0 281000.0 0.39 0.4287 0.9595 2070939 Maybridge1_003258 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(Cl)sc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M03 compound treatment 778985.0 214000.0 0.3 923160.0 308000.0 0.43 0.5192 0.9856 1504154 Maybridge1_003259 Fc1cc(CSc2nc3ccccc3[nH]2)c4OCOCc4c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M04 compound treatment 789023.0 224000.0 0.32 932197.0 317000.0 0.44 0.5382 0.9869 2070940 Maybridge1_003260 CC(=O)c1nnn(c1C)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M05 compound treatment 807114.0 242000.0 0.34 934217.0 319000.0 0.45 0.5584 0.9918 2070941 Maybridge1_003261 COC(=O)c1sccc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M06 compound treatment 808026.0 243000.0 0.35 954384.0 340000.0 0.47 0.5792 0.988 2070942 Maybridge1_003262 CS/C(=N\C#N)/N1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M07 compound treatment 826477.0 261000.0 0.37 970919.0 356000.0 0.5 0.6141 0.9898 2070943 Maybridge1_003263 Cc1onc(c1C(=O)c2ccc(F)cc2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M08 compound treatment 825996.0 261000.0 0.37 929532.0 315000.0 0.44 0.5728 0.9965 2070944 Maybridge1_003264 CC(=O)c1cnc(N)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M09 compound treatment 850949.0 286000.0 0.41 900191.0 285000.0 0.4 0.5689 0.9999 2070945 Maybridge1_003265 CN(C)c1cccc(N(C)C)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M10 compound treatment 803326.0 238000.0 0.34 953554.0 339000.0 0.47 0.5737 0.9867 2070946 Maybridge1_003266 NC(=O)C1CCN(CC1)c2ncccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M11 compound treatment 874762.0 310000.0 0.44 983858.0 369000.0 0.51 0.6754 0.997 2070947 Maybridge1_003267 CS(=O)(=O)c1cc(cc(c1S(=O)(=O)C)S(=O)(=O)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M12 compound treatment 839155.0 274000.0 0.39 941202.0 326000.0 0.46 0.5975 0.997 1469154 Maybridge1_003268 Clc1ccc(NC(=O)NC(=O)C2CCN(CC2)c3cccc(Cl)c3C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M13 compound treatment 892015.0 327000.0 0.46 976851.0 362000.0 0.51 0.6858 0.9991 2070948 Maybridge1_003269 Nc1oc(c(C#N)c1c2ccc(Cl)cc2Cl)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M14 compound treatment 852716.0 288000.0 0.41 968134.0 353000.0 0.49 0.6377 0.9957 2070949 Maybridge1_003270 CNC(=O)c1cnn(c1COC)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M15 compound treatment 902715.0 338000.0 0.48 988269.0 374000.0 0.52 0.7078 0.9992 1054566 Maybridge1_003271 NC(=O)c1ccc(cc1C(=O)N)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M16 compound treatment 868453.0 303000.0 0.43 949636.0 335000.0 0.47 0.6353 0.9992 2070950 Maybridge1_003272 Fc1ccc(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M17 compound treatment 898674.0 334000.0 0.47 982248.0 368000.0 0.51 0.6978 0.9992 2070951 Maybridge1_003273 CC(OS(=O)(=O)c1ccc(Cl)cc1)c2nc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M18 compound treatment 856293.0 291000.0 0.41 965203.0 350000.0 0.49 0.6384 0.9966 2070952 Maybridge1_003274 Cc1nc(NC(=N)N)sc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M19 compound treatment 903856.0 339000.0 0.48 963363.0 349000.0 0.49 0.6844 1.0 2070953 Maybridge1_003275 N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M20 compound treatment 828221.0 263000.0 0.37 922869.0 308000.0 0.43 0.5684 0.9976 2070954 Maybridge1_003276 CC(=O)C1=C(C)Nc2ccccc2S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M21 compound treatment 885586.0 320000.0 0.46 953330.0 339000.0 0.47 0.6562 0.9998 2070955 Maybridge1_003277 CC(=O)c1cnn(c1C)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M22 compound treatment 845540.0 280000.0 0.4 935784.0 321000.0 0.45 0.5986 0.9983 1326338 Maybridge1_003278 O=C1CC(CC(=O)C1)c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M23 mock treatment 880057.0 315000.0 0.45 976416.0 362000.0 0.5 0.6734 0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 M24 mock treatment 703758.0 139000.0 0.2 744871.0 130000.0 0.18 0.2677 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N01 compound treatment 782190.0 217000.0 0.31 860221.0 245000.0 0.34 0.4604 0.9987 2070956 Maybridge1_003279 N#CC1CN(Cc2ccccc2)CN(Cc3ccccc3)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N02 compound treatment 763276.0 198000.0 0.28 881519.0 267000.0 0.37 0.4624 0.9906 1083103 Maybridge1_003280 Cc1ccc(NC(=O)CC#N)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N03 compound treatment 767634.0 203000.0 0.29 913994.0 299000.0 0.42 0.4988 0.9836 1644674 Maybridge1_003281 COc1cc(CO)c(cc1OC)c2c[nH][nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N04 compound treatment 803072.0 238000.0 0.34 946015.0 331000.0 0.46 0.566 0.9883 1437622 Maybridge1_003282 COc1ccc(CCNS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N05 compound treatment 854943.0 290000.0 0.41 911096.0 296000.0 0.41 0.5837 1.0 1322518 Maybridge1_003283 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N06 compound treatment 804142.0 239000.0 0.34 967601.0 353000.0 0.49 0.5883 0.9837 1211475 Maybridge1_003284 COc1cccc(NC(=S)C(C#N)C(=O)N2CCCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N07 compound treatment 913855.0 349000.0 0.5 1023812.0 409000.0 0.57 0.7541 0.9976 1530793 Maybridge1_003285 CCOC(=O)c1cc(C#N)c2ccccn2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N08 compound treatment 762300.0 197000.0 0.28 884571.0 270000.0 0.38 0.4644 0.9895 1533510 Maybridge1_003286 Clc1ccc(cc1)c2nn(c3ccccc3)c(=O)c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N09 compound treatment 796212.0 231000.0 0.33 996531.0 382000.0 0.53 0.6089 0.9731 2070957 Maybridge1_003287 OCC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N10 compound treatment 862072.0 297000.0 0.42 943224.0 328000.0 0.46 0.6226 0.9992 1021562 Maybridge1_003288 COc1ccc(cc1)C(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N11 compound treatment 917721.0 353000.0 0.5 983918.0 369000.0 0.51 0.7186 0.9999 1660239 Maybridge1_003289 COc1ccc(Oc2ccc(cc2)c3ccn[nH]3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N12 compound treatment 877960.0 313000.0 0.44 921646.0 307000.0 0.43 0.6172 0.9998 2070958 Maybridge1_003290 FC(F)(F)c1cccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N13 compound treatment 875183.0 310000.0 0.44 916405.0 302000.0 0.42 0.6093 0.9997 2070959 Maybridge1_003291 Cc1nccnc1c2ccn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N14 compound treatment 822457.0 257000.0 0.37 892800.0 278000.0 0.39 0.533 0.9996 1917407 Maybridge1_003292 COc1cc(/C=N/NC(=S)N)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N15 compound treatment 885033.0 320000.0 0.45 1011003.0 396000.0 0.55 0.7125 0.9953 1091122 Maybridge1_003293 O=S1(=O)CCN(Cc2ccco2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N16 compound treatment 892553.0 327000.0 0.47 950186.0 335000.0 0.47 0.6601 1.0 1636044 Maybridge1_003294 Cc1ccc(Nc2ncnc3ccccc23)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N17 compound treatment 905279.0 340000.0 0.48 969164.0 354000.0 0.49 0.6916 0.9999 2070960 Maybridge1_003295 Clc1ccc(/N=C/c2ccc(C#N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N18 compound treatment 898256.0 333000.0 0.47 971194.0 356000.0 0.5 0.6865 0.9997 1191412 Maybridge1_003296 O=c1n(Cc2ccccc2)ncc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N19 compound treatment 892890.0 328000.0 0.47 992525.0 378000.0 0.53 0.7022 0.9981 2070961 Maybridge1_003297 CCOC(=O)c1c[nH]c2ccc(cc2c1=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N20 compound treatment 882300.0 317000.0 0.45 945498.0 331000.0 0.46 0.6451 0.9999 1226007 Maybridge1_003298 Nc1ccccc1C(=O)NC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N21 compound treatment 1041806.0 477000.0 0.68 1080316.0 466000.0 0.65 0.9385 0.9998 2070962 Maybridge1_003299 COc1cc(/C=N/NC(=O)CC#N)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N22 compound treatment 876940.0 312000.0 0.44 917111.0 302000.0 0.42 0.6118 0.9997 2070963 Maybridge1_003300 Clc1ccccc1/C=C/2\CCC/C(=C\c3ccccc3Cl)/C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N23 mock treatment 931181.0 366000.0 0.52 967853.0 353000.0 0.49 0.7163 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 N24 mock treatment 693393.0 128000.0 0.18 740280.0 126000.0 0.18 0.2528 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O01 compound treatment 733475.0 168000.0 0.24 836406.0 222000.0 0.31 0.3879 0.992 1263209 Maybridge1_003301 CC(C)(C)c1nc(N)sc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O02 compound treatment 723256.0 158000.0 0.22 832907.0 218000.0 0.3 0.3742 0.9889 2070964 Maybridge1_003302 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O03 compound treatment 760888.0 196000.0 0.28 913994.0 299000.0 0.42 0.492 0.9806 2070965 Maybridge1_003303 Brc1cc(Br)cc(CSc2ccccn2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O04 compound treatment 731048.0 166000.0 0.24 908875.0 294000.0 0.41 0.4569 0.9655 1171047 Maybridge1_003304 Fc1ccc(cc1)C(=O)C2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O05 compound treatment 819609.0 254000.0 0.36 932368.0 318000.0 0.44 0.5691 0.995 1441367 Maybridge1_003305 CC(C)(C)C(=O)c1sc2sc(C(=O)C(C)(C)C)c(N)c2c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O06 compound treatment 739944.0 175000.0 0.25 860820.0 246000.0 0.34 0.4185 0.9875 2070966 Maybridge1_003306 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1N2CCNCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O07 compound treatment 794620.0 229000.0 0.33 946497.0 332000.0 0.46 0.558 0.9854 1985191 Maybridge1_003307 COC(=O)c1sccc1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O08 compound treatment 769376.0 204000.0 0.29 935756.0 321000.0 0.45 0.522 0.978 2070967 Maybridge1_003308 CS/C(=N\C#N)/NC1CCCCNC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O09 compound treatment 789481.0 224000.0 0.32 950429.0 336000.0 0.47 0.5567 0.9825 2070968 Maybridge1_003309 NC(=O)c1ccc(cc1)C(=N)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O10 compound treatment 810841.0 246000.0 0.35 860704.0 246000.0 0.34 0.4897 1.0 2070969 Maybridge1_003310 CN(C)/C=N/C(=O)C1CCN(CC1)c2cccc(F)c2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O11 compound treatment 779639.0 215000.0 0.31 944008.0 329000.0 0.46 0.5404 0.9802 2070970 Maybridge1_003311 CN(C)/C=C/1\C(=O)ON=C1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O12 compound treatment 794711.0 230000.0 0.33 916631.0 302000.0 0.42 0.5286 0.9921 2070971 Maybridge1_003312 CSC1=NS(=O)(=O)c2c(C)nn(C)c2S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O13 compound treatment 807411.0 242000.0 0.34 946656.0 332000.0 0.46 0.571 0.9894 2070972 Maybridge1_003313 Cc1n[nH]cc1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O14 compound treatment 821234.0 256000.0 0.36 908610.0 294000.0 0.41 0.5474 0.9983 2070973 Maybridge1_003314 Cc1c(nnn1c2ccc(Cl)cc2Cl)c3ccnc(N)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O15 compound treatment 886536.0 321000.0 0.46 940286.0 326000.0 0.45 0.6443 1.0 1419671 Maybridge1_003315 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O16 compound treatment 759130.0 194000.0 0.28 878183.0 263000.0 0.37 0.4549 0.99 2070974 Maybridge1_003316 Fc1ccc(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O17 compound treatment 898640.0 334000.0 0.47 962681.0 348000.0 0.49 0.6785 0.9999 2070975 Maybridge1_003317 [O-][N+](=O)c1cccnc1NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O18 compound treatment 840601.0 275000.0 0.39 923999.0 309000.0 0.43 0.582 0.9988 2070976 Maybridge1_003318 OC(=O)c1cc(Br)cc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O19 compound treatment 869822.0 305000.0 0.43 922306.0 308000.0 0.43 0.6097 1.0 2070977 Maybridge1_003319 CN(C)/C=N/C(=N\OCc1c(F)cccc1Cl)/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O20 compound treatment 834390.0 269000.0 0.38 918280.0 304000.0 0.42 0.5701 0.9987 2070978 Maybridge1_003320 Fc1cccc(Cl)c1/C=C/c2cnc3ccccc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O21 compound treatment 867649.0 303000.0 0.43 967534.0 353000.0 0.49 0.6521 0.9978 2070979 Maybridge1_003321 CS/C(=N/C#N)/NCCSC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O22 compound treatment 821632.0 256000.0 0.36 878791.0 264000.0 0.37 0.5183 1.0 2070980 Maybridge1_003322 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCc2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O23 mock treatment 866007.0 301000.0 0.43 948347.0 334000.0 0.47 0.6316 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 O24 mock treatment 468487.0 -96600.0 -0.14 553907.0 -60800.0 -0.08 -0.1572 -0.9731 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P01 compound treatment 770771.0 206000.0 0.29 834124.0 219000.0 0.31 0.4231 0.9997 2070981 Maybridge1_003323 CSC(=NS(=O)(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P02 compound treatment 784249.0 219000.0 0.31 852828.0 238000.0 0.33 0.4551 0.9995 1083128 Maybridge1_003324 Cc1ccccc1NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P03 compound treatment 781032.0 216000.0 0.31 862658.0 248000.0 0.35 0.4616 0.9982 2070982 Maybridge1_003325 CN(C)/C=N/C(=O)c1sc(C#N)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P04 compound treatment 781494.0 216000.0 0.31 875136.0 260000.0 0.36 0.4744 0.9966 1735768 Maybridge1_003326 COc1ccccc1Nc2snc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P05 compound treatment 795143.0 230000.0 0.33 894180.0 279000.0 0.39 0.5069 0.9962 2070983 Maybridge1_003327 CC(=O)C1C(=O)CC(CC1=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P06 compound treatment 795582.0 230000.0 0.33 873884.0 259000.0 0.36 0.4873 0.9988 1585004 Maybridge1_003328 COc1cccc(NC(=S)C(C#N)C(=O)N2CCC(C)CC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P07 compound treatment 809088.0 244000.0 0.35 869438.0 255000.0 0.36 0.4965 0.9999 2070984 Maybridge1_003329 Fc1ccccc1S(=O)(=O)CCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P08 compound treatment 810364.0 245000.0 0.35 854973.0 240000.0 0.34 0.4835 0.9998 1007678 Maybridge1_003330 Cc1ccc(cc1)C(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P09 compound treatment 815347.0 250000.0 0.36 850912.0 236000.0 0.33 0.4845 0.9993 2070985 Maybridge1_003331 CC(=O)c1ccc(o1)c2ccc(F)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P10 compound treatment 809584.0 244000.0 0.35 862396.0 248000.0 0.35 0.4901 1.0 1101361 Maybridge1_003332 N1C(Nc2ccccc12)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P11 compound treatment 811175.0 246000.0 0.35 851760.0 237000.0 0.33 0.4812 0.9996 1282449 Maybridge1_003333 Nc1c(cnn1c2cc(Cl)cc(Cl)c2)c3nn[nH]n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P12 compound treatment 863312.0 298000.0 0.42 888756.0 274000.0 0.38 0.5701 0.9987 1612743 Maybridge1_003334 Cc1ccc(NC(=O)c2ccccc2NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P13 compound treatment 820682.0 256000.0 0.36 866007.0 251000.0 0.35 0.5048 0.9998 2070986 Maybridge1_003335 Cc1nc(COc2ccc(C#N)cc2)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P14 compound treatment 865472.0 300000.0 0.43 859891.0 245000.0 0.34 0.5438 0.9939 1029735 Maybridge1_003336 OC(=O)CC1SC(=N)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P15 compound treatment 854400.0 289000.0 0.41 904923.0 290000.0 0.4 0.5771 1.0 2070987 Maybridge1_003337 Clc1ccc(SCCS(=O)(=O)CCSc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P16 compound treatment 884985.0 320000.0 0.45 900031.0 285000.0 0.4 0.603 0.9978 2070988 Maybridge1_003338 O=C1OCCC/N=C(/c2ccccc2)\c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P17 compound treatment 886969.0 322000.0 0.46 919696.0 305000.0 0.43 0.6244 0.9993 2070989 Maybridge1_003339 Clc1ccc(/C=N/c2cc(Cl)cc(Cl)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P18 compound treatment 882526.0 317000.0 0.45 910486.0 296000.0 0.41 0.6108 0.999 2070990 Maybridge1_003340 Cc1ccc(cc1)C(=O)CSC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P19 compound treatment 897763.0 333000.0 0.47 910812.0 296000.0 0.41 0.6265 0.9977 1133957 Maybridge1_003341 OC(=O)C1CN(Cc2cccs2)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P20 compound treatment 860705.0 296000.0 0.42 927149.0 312000.0 0.44 0.6053 0.9998 1913964 Maybridge1_003342 Cc1ccc(cc1C)n2nnc3ccccc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P21 compound treatment 870324.0 305000.0 0.43 896521.0 282000.0 0.39 0.5848 0.9988 2070991 Maybridge1_003343 COc1ccc(/C=N/NC(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P22 compound treatment 1162784.0 598000.0 0.85 1079857.0 465000.0 0.65 1.0597 0.9911 2070992 Maybridge1_003344 O=C/1/C(=C/c2ccco2)/CCC\C1=C/c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P23 mock treatment 827946.0 263000.0 0.37 871039.0 256000.0 0.36 0.517 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.550 P24 mock treatment 264146.0 -301000.0 -0.43 324202.0 -291000.0 -0.41 -0.5892 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A01 compound treatment 832269.0 250000.0 0.36 838544.0 258000.0 0.36 0.5066 1.0 2070993 Maybridge1_003345 O=C/1/C(=C/c2cccs2)/CCC\C1=C/c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A02 compound treatment 785499.0 204000.0 0.29 817749.0 237000.0 0.33 0.439 0.9978 2070994 Maybridge1_003346 CSC1=NCCN1C(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A03 compound treatment 790450.0 209000.0 0.3 844719.0 264000.0 0.37 0.4706 0.9942 2070995 Maybridge1_003347 Clc1ccccc1/C=C/2\CC/C(=C\c3ccccc3Cl)/C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A04 compound treatment 781469.0 200000.0 0.28 824290.0 244000.0 0.34 0.4414 0.9959 2070996 Maybridge1_003348 Clc1ccc(cc1)c2csc(Nc3ccccc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A05 compound treatment 794908.0 213000.0 0.3 873244.0 293000.0 0.41 0.5032 0.9892 2070997 Maybridge1_003349 CN1C/C(=C\C=C\c2ccccc2)/C(=O)\C(=C\C=C\c3ccccc3)\C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A06 compound treatment 854466.0 273000.0 0.39 891687.0 311000.0 0.43 0.5813 0.9984 2070998 Maybridge1_003350 Cc1cc(C)c(CS/C(=N/N)/N)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A07 compound treatment 864496.0 283000.0 0.4 920704.0 340000.0 0.47 0.62 0.9966 2070999 Maybridge1_003351 Cc1ccc(CSC2=NCCN2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A08 compound treatment 874374.0 293000.0 0.42 910168.0 330000.0 0.46 0.6195 0.9987 2071000 Maybridge1_003352 Cc1c(C)c(C)c(CSC2=NCCCN2C3CCCCC3)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A09 compound treatment 869790.0 288000.0 0.41 930499.0 350000.0 0.49 0.635 0.9962 2071001 Maybridge1_003353 C(SC1=NCCCN1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A10 compound treatment 884304.0 302000.0 0.43 924311.0 344000.0 0.48 0.6435 0.9985 1664303 Maybridge1_003354 CC(=O)Nc1ccc(cc1)C(=C(C#N)C#N)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A11 compound treatment 894180.0 312000.0 0.44 917267.0 337000.0 0.47 0.6465 0.9996 2071002 Maybridge1_003355 Cc1c(C)c(C)c(CSC2=NCCN2Cc3ccccc3)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A12 compound treatment 890543.0 309000.0 0.44 922737.0 342000.0 0.48 0.6482 0.9991 2071003 Maybridge1_003356 Clc1ccc(cc1)C2=NC(N=C(S2)c3ccc(Cl)cc3)c4ccc(Cl)c(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A13 compound treatment 894926.0 313000.0 0.45 922985.0 343000.0 0.48 0.6528 0.9994 2071004 Maybridge1_003357 CNC(=S)N/N=C(\C)/c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A14 compound treatment 905432.0 324000.0 0.46 949448.0 369000.0 0.51 0.6895 0.9984 2071005 Maybridge1_003358 Cc1ccc(CSC2=NCN(CN2)C(C)(C)CC(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A15 compound treatment 917467.0 336000.0 0.48 948358.0 368000.0 0.51 0.7005 0.9993 2071006 Maybridge1_003359 Clc1ccc2OC(Nc2c1)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A16 compound treatment 901072.0 319000.0 0.45 935611.0 355000.0 0.5 0.6715 0.999 2071007 Maybridge1_003360 CCOC(=O)c1sc2ccccc2c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A17 compound treatment 923372.0 342000.0 0.49 943270.0 363000.0 0.51 0.7015 0.9998 1345383 Maybridge1_003361 N1C(c2ccccc2)n3c(nc4ccccc34)-c5ccccc15 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A18 compound treatment 901240.0 319000.0 0.45 941587.0 361000.0 0.5 0.6775 0.9987 2071008 Maybridge1_003362 FC(F)(F)c1nn2cc(nc2s1)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A19 compound treatment 918069.0 336000.0 0.48 935585.0 355000.0 0.5 0.6885 0.9998 1222161 Maybridge1_003363 N1C(Oc2ccccc12)c3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A20 compound treatment 901316.0 320000.0 0.45 924052.0 344000.0 0.48 0.6603 0.9996 2071009 Maybridge1_003364 Clc1cc(Cl)c(Cl)c(I)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A21 compound treatment 885244.0 303000.0 0.43 921513.0 341000.0 0.48 0.6417 0.9988 2071010 Maybridge1_003365 CCN1CNC(=NC1)SCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A22 compound treatment 861280.0 279000.0 0.4 882235.0 302000.0 0.42 0.5788 0.9996 1879466 Maybridge1_003366 [O-][N+](=O)c1ccc(cc1)C(=O)NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A23 mock treatment 865898.0 284000.0 0.4 845554.0 265000.0 0.37 0.5473 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 A24 mock treatment 147752.0 -434000.0 -0.62 151807.0 -428000.0 -0.6 -0.859 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B01 compound treatment 762728.0 181000.0 0.26 830236.0 250000.0 0.35 0.4284 0.9888 2071011 Maybridge1_003367 Clc1ccccc1CSC2=Nc3ccccc3C(=O)NN2c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B02 compound treatment 756264.0 174000.0 0.25 808810.0 229000.0 0.32 0.4008 0.9923 1510166 Maybridge1_003368 Clc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B03 compound treatment 789114.0 207000.0 0.29 924512.0 344000.0 0.48 0.5479 0.9726 2071012 Maybridge1_003369 [O-][N+](=O)c1ccc(SC2=NCCN2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B04 compound treatment 785192.0 203000.0 0.29 912612.0 332000.0 0.46 0.5323 0.9742 1291880 Maybridge1_003370 CCOC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B05 compound treatment 797995.0 216000.0 0.31 932063.0 352000.0 0.49 0.5643 0.9747 1085749 Maybridge1_003371 CCOC(=O)CSc1ccc(cc1Cl)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B06 compound treatment 804920.0 223000.0 0.32 903264.0 323000.0 0.45 0.5429 0.9853 1454539 Maybridge1_003372 Cc1onc(c1C(=O)Nc2ccc(F)c(F)c2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B07 compound treatment 847931.0 266000.0 0.38 953141.0 373000.0 0.52 0.6353 0.9878 2071013 Maybridge1_003373 CC(C)c1ccc(/N=C/c2cc(Br)ccc2O)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B08 compound treatment 832247.0 250000.0 0.36 878255.0 298000.0 0.42 0.5457 0.997 2071014 Maybridge1_003374 NS(=O)(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B09 compound treatment 853341.0 272000.0 0.39 985847.0 406000.0 0.57 0.673 0.9827 1658093 Maybridge1_003375 COc1ccc(CCNC2(CCCCC2)C#N)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B10 compound treatment 873609.0 292000.0 0.41 920503.0 340000.0 0.47 0.629 0.9978 2071015 Maybridge1_003376 ClC(Cl)(Cl)C(=O)N1CCc2ccccc2C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B11 compound treatment 857722.0 276000.0 0.39 918122.0 338000.0 0.47 0.6106 0.9959 1004134 Maybridge1_003377 CCOC(=O)NCc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B12 compound treatment 840864.0 259000.0 0.37 887475.0 307000.0 0.43 0.5635 0.9972 2071016 Maybridge1_003378 Cc1ccc(nc1)N2C(=O)C3C4CC(C=C4)C3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B13 compound treatment 897630.0 316000.0 0.45 910271.0 330000.0 0.46 0.643 0.9999 1410553 Maybridge1_003379 CC(C)N(CCC#N)C(=O)c1c(C)onc1c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B14 compound treatment 885228.0 303000.0 0.43 911087.0 331000.0 0.46 0.6314 0.9994 1690979 Maybridge1_003380 Cc1cccc(NC(=S)NCc2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B15 compound treatment 878159.0 296000.0 0.42 948813.0 369000.0 0.51 0.6615 0.9951 2071017 Maybridge1_003381 O=C/1C2CCN(CC2)\C1=C/c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B16 compound treatment 904380.0 323000.0 0.46 882760.0 302000.0 0.42 0.6227 0.9991 1200805 Maybridge1_003382 COc1ccccc1NC(=S)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B17 compound treatment 933748.0 352000.0 0.5 943326.0 363000.0 0.51 0.7119 1.0 2071018 Maybridge1_003383 C=C1S/C(=N/c2ccc(cc2)S(=O)(=O)N3CCCCC3)/NC41CCCCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B18 compound treatment 871588.0 290000.0 0.41 896238.0 316000.0 0.44 0.603 0.9994 2071019 Maybridge1_003384 Cc1ccccc1NC(=S)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B19 compound treatment 1951055.0 1370000.0 1.95 2010529.0 1430000.0 1.99 2.7874 0.9999 2071020 Maybridge1_003385 C[C@@]1(CCC2C(CCC3C[C@H](O)CC[C@@]32C)C1/C=C\4/Nc5ccccc5C4=O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B20 compound treatment 859555.0 278000.0 0.39 846118.0 266000.0 0.37 0.5415 0.9995 2071021 Maybridge1_003386 COc1cccc(NC(=S)N2CC(C)OC(C)C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B21 compound treatment 901122.0 319000.0 0.45 877369.0 297000.0 0.41 0.6141 0.999 1162137 Maybridge1_003387 Clc1ccc(cc1Cl)C(NCc2ccccc2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B22 compound treatment 858607.0 277000.0 0.39 841678.0 261000.0 0.36 0.5361 0.9993 2071022 Maybridge1_003388 Cc1ccc(NC(=S)NCc2ccncc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B23 mock treatment 878215.0 296000.0 0.42 813698.0 233000.0 0.33 0.5283 0.9919 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 B24 mock treatment 165847.0 -416000.0 -0.59 149659.0 -431000.0 -0.6 -0.843 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C01 compound treatment 694805.0 113000.0 0.16 751105.0 171000.0 0.24 0.2821 0.9816 2071023 Maybridge1_003389 O=C/1/C(=C/c2ccccc2)/CC\C1=C/c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C02 compound treatment 687474.0 106000.0 0.15 769456.0 189000.0 0.26 0.2928 0.9644 2071024 Maybridge1_003390 Clc1ccc(cc1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C03 compound treatment 1103805.0 522000.0 0.74 1101275.0 521000.0 0.73 1.0387 0.9999 2071025 Maybridge1_003391 CN(C)c1ccc(/C=C/2\CCC/C(=C\c3ccc(cc3)N(C)C)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C04 compound treatment 699567.0 118000.0 0.17 817507.0 237000.0 0.33 0.3524 0.9502 2071026 Maybridge1_003392 NC(=S)Cc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C05 compound treatment 734189.0 152000.0 0.22 821038.0 241000.0 0.34 0.3907 0.9775 1433637 Maybridge1_003393 CNc1ccc(Cl)cc1C(=O)NCCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C06 compound treatment 737481.0 156000.0 0.22 803607.0 223000.0 0.31 0.3768 0.986 1101362 Maybridge1_003394 CC(O)CN1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C07 compound treatment 767102.0 185000.0 0.26 845318.0 265000.0 0.37 0.4477 0.9862 1018871 Maybridge1_003395 C(SC1=NCCN1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C08 compound treatment 774629.0 193000.0 0.27 858454.0 278000.0 0.39 0.4682 0.9856 2071027 Maybridge1_003396 Clc1cccc(Cl)c1CSC2=NCCCN2C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C09 compound treatment 802625.0 221000.0 0.31 891143.0 311000.0 0.43 0.5286 0.9875 2071028 Maybridge1_003397 CC1CNC(=N1)SCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C10 compound treatment 787357.0 206000.0 0.29 850972.0 271000.0 0.38 0.4737 0.992 2071029 Maybridge1_003398 COc1ccc(cc1OC)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C11 compound treatment 817998.0 236000.0 0.34 872439.0 292000.0 0.41 0.5256 0.9954 2071030 Maybridge1_003399 Cc1c(C)c(C)c(CSc2nc3ccccc3[nH]2)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C12 compound treatment 802939.0 221000.0 0.31 821520.0 241000.0 0.34 0.4603 0.9994 1734920 Maybridge1_003400 Brc1ccc(cc1)c2csc(=N)n2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C13 compound treatment 799038.0 217000.0 0.31 823854.0 244000.0 0.34 0.4587 0.9989 2071031 Maybridge1_003401 CNC(=S)N/N=C(\C)/c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C14 compound treatment 862534.0 281000.0 0.4 896771.0 316000.0 0.44 0.5944 0.9987 2071032 Maybridge1_003402 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2c(nc3ccccc3c2=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C15 compound treatment 868703.0 287000.0 0.41 919836.0 340000.0 0.47 0.6234 0.9972 2071033 Maybridge1_003403 COc1ccc(cc1)C2Nc3cc(Cl)ccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C16 compound treatment 801932.0 220000.0 0.31 889289.0 309000.0 0.43 0.5261 0.9877 2071034 Maybridge1_003404 Clc1ccc(cc1)C(=N)NCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C17 compound treatment 810133.0 228000.0 0.32 898114.0 318000.0 0.44 0.543 0.9883 2071035 Maybridge1_003405 CN(C)c1ccc(C2Nc3ccccc3O2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C18 compound treatment 789480.0 208000.0 0.3 883163.0 303000.0 0.42 0.5075 0.9847 2071036 Maybridge1_003406 CCOC(=O)c1c(NC(=O)COc2ccccc2)sc3CCCCc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C19 compound treatment 823580.0 242000.0 0.34 892792.0 313000.0 0.44 0.5513 0.9931 1150673 Maybridge1_003407 COc1cc(cc(OC)c1OC)C2Nc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C20 compound treatment 795033.0 213000.0 0.3 838855.0 259000.0 0.36 0.4694 0.9963 1057038 Maybridge1_003408 CNc1ccccc1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C21 compound treatment 823538.0 242000.0 0.34 884775.0 304000.0 0.42 0.5434 0.9945 2071037 Maybridge1_003409 CCN1CNC(=NC1)SCc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C22 compound treatment 796284.0 214000.0 0.31 855329.0 275000.0 0.38 0.4869 0.9935 2071038 Maybridge1_003410 [O-][N+](=O)c1ccc(N2CCOCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C23 mock treatment 816580.0 235000.0 0.33 872179.0 292000.0 0.41 0.524 0.9951 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 C24 mock treatment 152677.0 -429000.0 -0.61 174952.0 -405000.0 -0.57 -0.8313 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D01 compound treatment 769327.0 188000.0 0.27 822009.0 242000.0 0.34 0.427 0.9933 1049869 Maybridge1_003411 OC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D02 compound treatment 752152.0 170000.0 0.24 824114.0 244000.0 0.34 0.4118 0.9862 2071039 Maybridge1_003412 OC1=NC(Nc2ccccc12)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D03 compound treatment 824466.0 243000.0 0.35 920274.0 340000.0 0.47 0.5793 0.9878 2071040 Maybridge1_003413 [O-][N+](=O)c1ccc(Sc2ccccc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D04 compound treatment 795235.0 213000.0 0.3 944488.0 364000.0 0.51 0.5738 0.9697 1922174 Maybridge1_003414 Oc1ccccc1/C=N/c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D05 compound treatment 836595.0 255000.0 0.36 906716.0 326000.0 0.46 0.5781 0.9936 2071041 Maybridge1_003415 Cc1ccc(C(=O)NNC(=O)c2ccncc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D06 compound treatment 826825.0 245000.0 0.35 936919.0 357000.0 0.5 0.5981 0.9848 1180385 Maybridge1_003416 Cc1c(C)c(C)c(CSCC(=O)NN)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D07 compound treatment 845036.0 263000.0 0.37 898432.0 318000.0 0.44 0.5785 0.9964 1484448 Maybridge1_003417 Clc1ccc2oc(cc2c1)c3csc(NCC=C)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D08 compound treatment 869086.0 287000.0 0.41 966119.0 386000.0 0.54 0.6694 0.9908 2071042 Maybridge1_003418 [O-][N+](=O)c1cc(ccc1Sc2ccccn2)C(=O)N3CCC=CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D09 compound treatment 898072.0 316000.0 0.45 967253.0 387000.0 0.54 0.6997 0.9959 1675509 Maybridge1_003419 CC(C)c1ccc(NC2(CCCCC2)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D10 compound treatment 869078.0 287000.0 0.41 928058.0 348000.0 0.49 0.6319 0.9964 2071043 Maybridge1_003420 ClC(Cl)(Cl)C(=O)N1CCN2C(=O)c3ccccc3C12c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D11 compound treatment 905406.0 324000.0 0.46 969816.0 390000.0 0.54 0.7096 0.9966 2071044 Maybridge1_003421 Nc1ccc(Cl)cc1/C(=N/O)/c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D12 compound treatment 924070.0 342000.0 0.49 959535.0 379000.0 0.53 0.7182 0.9991 2071045 Maybridge1_003422 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccc(n4)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D13 compound treatment 942406.0 361000.0 0.51 952558.0 372000.0 0.52 0.7298 1.0 1204368 Maybridge1_003423 COC(=O)c1ccccc1NC(=O)c2c(C)onc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D14 compound treatment 876399.0 295000.0 0.42 967630.0 387000.0 0.54 0.6782 0.9921 2071046 Maybridge1_003424 Cc1ccc(NC(=S)NCc2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D15 compound treatment 931514.0 350000.0 0.5 1037218.0 457000.0 0.64 0.8023 0.9925 2071047 Maybridge1_003425 COc1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D16 compound treatment 916850.0 335000.0 0.48 1031061.0 451000.0 0.63 0.7815 0.9906 2071048 Maybridge1_003426 Clc1ccccc1NC(=S)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D17 compound treatment 934589.0 353000.0 0.5 1042212.0 462000.0 0.64 0.8103 0.9923 2071049 Maybridge1_003427 COc1cccc(/N=C\2/NC(C)(C)C(=C)S2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D18 compound treatment 866170.0 284000.0 0.4 1002375.0 422000.0 0.59 0.7022 0.9832 2071050 Maybridge1_003428 COc1ccc(NC(=S)N2CCOCC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D19 compound treatment 4049632.0 3470000.0 4.93 4702899.0 4120000.0 5.75 7.5529 0.9971 2071051 Maybridge1_003429 C[C@@]1(CCC2C(CCC3CC=CC[C@@]32C)C1/C=C\4/Nc5ccccc5C4=O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D20 compound treatment 920116.0 338000.0 0.48 955129.0 375000.0 0.52 0.7099 0.9991 2071052 Maybridge1_003430 COc1ccccc1NC(=S)N2CC(C)OC(C)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D21 compound treatment 974770.0 393000.0 0.56 935820.0 356000.0 0.5 0.7458 0.9982 1698522 Maybridge1_003431 COc1ccc(CCNC(C#N)c2ccc(Cl)c(Cl)c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D22 compound treatment 913682.0 332000.0 0.47 949345.0 369000.0 0.51 0.6977 0.9991 2071053 Maybridge1_003432 Cc1cccc(C)c1NC(=S)NCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D23 mock treatment 943022.0 361000.0 0.51 964662.0 384000.0 0.54 0.7423 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 D24 mock treatment 164202.0 -418000.0 -0.59 154646.0 -426000.0 -0.59 -0.8397 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E01 compound treatment 773382.0 192000.0 0.27 862079.0 282000.0 0.39 0.4706 0.984 2071054 Maybridge1_003433 COc1cc(C#N)c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E02 compound treatment 783295.0 201000.0 0.29 917685.0 337000.0 0.47 0.5354 0.9717 2071055 Maybridge1_003434 S=C1NCN(Cc2ccccc2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E03 compound treatment 836921.0 255000.0 0.36 976584.0 396000.0 0.55 0.6474 0.9792 2071056 Maybridge1_003435 CN1C/C(=C\c2ccc(Cl)cc2)/C(=O)\C(=C\c3ccc(Cl)cc3)\C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E04 compound treatment 810113.0 228000.0 0.32 981578.0 401000.0 0.56 0.6253 0.9665 2071057 Maybridge1_003436 COc1ccc(CC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E05 compound treatment 864379.0 283000.0 0.4 1022240.0 442000.0 0.62 0.72 0.9785 1643078 Maybridge1_003437 CNc1ccccc1C(=O)NCCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E06 compound treatment 804906.0 223000.0 0.32 1000962.0 421000.0 0.59 0.6392 0.9583 1305363 Maybridge1_003438 Nc1nc(cs1)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E07 compound treatment 863073.0 281000.0 0.4 1025302.0 445000.0 0.62 0.7217 0.9774 2071058 Maybridge1_003439 Clc1ccc(CSC2=NCCN2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E08 compound treatment 834211.0 252000.0 0.36 984119.0 404000.0 0.56 0.6521 0.9763 2071059 Maybridge1_003440 N#Cc1ccc(CSC2=NCCCN2C3CCCCC3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E09 compound treatment 896055.0 314000.0 0.45 1007447.0 427000.0 0.6 0.7373 0.99 2071060 Maybridge1_003441 Cc1ccc(CSc2nc3ccccc3[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E10 compound treatment 891110.0 309000.0 0.44 1000018.0 420000.0 0.59 0.725 0.9901 2071061 Maybridge1_003442 COc1cc(cc(OC)c1OC)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E11 compound treatment 879295.0 297000.0 0.42 1012911.0 433000.0 0.6 0.7258 0.9849 2071062 Maybridge1_003443 CN(C)c1ccc(cc1)C2NN=C(N2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E12 compound treatment 878472.0 297000.0 0.42 1001067.0 421000.0 0.59 0.7133 0.9869 1055541 Maybridge1_003444 FC(F)(F)c1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E13 compound treatment 891785.0 310000.0 0.44 999563.0 419000.0 0.58 0.7252 0.9903 1922670 Maybridge1_003445 Nc1ccccc1C(=O)N/N=C/c2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E14 compound treatment 871338.0 290000.0 0.41 986110.0 406000.0 0.57 0.6914 0.9878 1085424 Maybridge1_003446 OC(=O)c1ccccc1NC(=O)COc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E15 compound treatment 926830.0 345000.0 0.49 1057600.0 477000.0 0.67 0.8177 0.9887 2071063 Maybridge1_003447 COc1ccc(OC)c(c1)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E16 compound treatment 918437.0 337000.0 0.48 1010452.0 430000.0 0.6 0.7627 0.9937 2071064 Maybridge1_003448 Nc1nnc(s1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E17 compound treatment 918395.0 337000.0 0.48 1052308.0 472000.0 0.66 0.804 0.9877 1267546 Maybridge1_003449 CN(C)c1ccc(C2Nc3cc(Cl)ccc3O2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E18 compound treatment 956446.0 375000.0 0.53 1023898.0 444000.0 0.62 0.8142 0.9972 2071065 Maybridge1_003450 NC(=S)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E19 compound treatment 1017972.0 436000.0 0.62 1081963.0 502000.0 0.7 0.9334 0.9982 1585575 Maybridge1_003451 CN(CCC#N)c1ccc(cc1)C2Nc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E20 compound treatment 913406.0 332000.0 0.47 1023782.0 444000.0 0.62 0.7708 0.991 1334251 Maybridge1_003452 Clc1ccccc1C(=O)NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E21 compound treatment 973346.0 392000.0 0.56 1005487.0 425000.0 0.59 0.8131 0.9995 2071066 Maybridge1_003453 COCCCN1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E22 compound treatment 926606.0 345000.0 0.49 1006901.0 427000.0 0.6 0.7675 0.9954 1726130 Maybridge1_003454 Nc1ccc(N2CCOCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E23 mock treatment 918733.0 337000.0 0.48 1006229.0 426000.0 0.59 0.7589 0.9943 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 E24 mock treatment 156962.0 -425000.0 -0.6 165826.0 -414000.0 -0.58 -0.8359 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F01 compound treatment 796448.0 215000.0 0.31 841678.0 261000.0 0.36 0.4736 0.9961 2071067 Maybridge1_003455 Cc1nnc(NC(=S)N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F02 compound treatment 781487.0 200000.0 0.28 906869.0 327000.0 0.46 0.5229 0.9741 1079948 Maybridge1_003456 Clc1ccccc1C2NC(=O)c3ccccc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F03 compound treatment 828868.0 247000.0 0.35 913953.0 334000.0 0.47 0.5775 0.9904 2071068 Maybridge1_003457 OC(=O)c1cc(ccc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F04 compound treatment 841384.0 260000.0 0.37 1009112.0 429000.0 0.6 0.6839 0.9731 1910594 Maybridge1_003458 Oc1c(Br)cc(Br)cc1/C=N/c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F05 compound treatment 866574.0 285000.0 0.4 901535.0 321000.0 0.45 0.6032 0.9987 2071069 Maybridge1_003459 FC(F)(F)c1cccc(c1)C(=O)NNC(=O)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F06 compound treatment 852136.0 270000.0 0.38 936847.0 357000.0 0.5 0.6235 0.9919 2071070 Maybridge1_003460 NNC(=O)CSc1ccccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F07 compound treatment 898975.0 317000.0 0.45 954525.0 374000.0 0.52 0.688 0.9974 2071071 Maybridge1_003461 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccc(Cl)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F08 compound treatment 853032.0 271000.0 0.39 929255.0 349000.0 0.49 0.6169 0.9934 2071072 Maybridge1_003462 [O-][N+](=O)c1ccc(NC(=O)c2ccc(Sc3ccc(Cl)cc3)c(c2)[N+](=O)[O-])nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F09 compound treatment 907696.0 326000.0 0.46 994764.0 414000.0 0.58 0.7365 0.994 1049326 Maybridge1_003463 Fc1ccc(cc1)C(=O)CCN2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F10 compound treatment 900922.0 319000.0 0.45 989707.0 409000.0 0.57 0.7247 0.9935 2071073 Maybridge1_003464 C/C(=N\O)/c1ccc(Cl)c(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F11 compound treatment 900125.0 318000.0 0.45 930240.0 350000.0 0.49 0.6652 0.9993 2071074 Maybridge1_003465 [O-][N+](=O)c1ccc(N/N=C/2\CCCCC2CCC#N)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F12 compound treatment 884749.0 303000.0 0.43 941111.0 361000.0 0.5 0.6605 0.997 1613737 Maybridge1_003466 COc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F13 compound treatment 936001.0 354000.0 0.5 973415.0 393000.0 0.55 0.7439 0.9991 1056544 Maybridge1_003467 CCOC(=O)c1c(N)sc2CCCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F14 compound treatment 920494.0 339000.0 0.48 996160.0 416000.0 0.58 0.7507 0.9957 1138910 Maybridge1_003468 COc1ccc(NC(=S)NCc2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F15 compound treatment 926971.0 345000.0 0.49 989465.0 409000.0 0.57 0.7506 0.9972 2071075 Maybridge1_003469 O=C/1C2CCN(CC2)\C1=C\c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F16 compound treatment 912534.0 331000.0 0.47 997232.0 417000.0 0.58 0.7438 0.9945 2071076 Maybridge1_003470 FC(F)(F)c1cccc(NC(=S)NCc2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F17 compound treatment 941194.0 359000.0 0.51 1015083.0 435000.0 0.61 0.7902 0.9964 2071077 Maybridge1_003471 Cc1ccc(/N=C\2/NC(C)(C)C(=C)S2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F18 compound treatment 923398.0 342000.0 0.49 941615.0 361000.0 0.5 0.6998 0.9998 2071078 Maybridge1_003472 CCOC(=O)c1ccc(NC(=S)N2CCOCC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F19 compound treatment 959221.0 377000.0 0.54 1023313.0 443000.0 0.62 0.8164 0.9975 2071079 Maybridge1_003473 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4cccc(c4)[N+](=O)[O-])cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F20 compound treatment 977266.0 395000.0 0.56 1012870.0 433000.0 0.6 0.8243 0.9994 2071080 Maybridge1_003474 Cc1onc(c1C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F21 compound treatment 998643.0 417000.0 0.59 1043416.0 463000.0 0.65 0.8759 0.9991 1271674 Maybridge1_003475 Brc1ccc(cc1)S(=O)(=O)N(CCC#N)CC2CCCO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F22 compound treatment 910830.0 329000.0 0.47 954280.0 374000.0 0.52 0.6997 0.9985 2071081 Maybridge1_003476 COc1cccc(NC(=S)N(CCC#N)C2CCCCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F23 mock treatment 960871.0 379000.0 0.54 992046.0 412000.0 0.57 0.7873 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 F24 mock treatment 170677.0 -411000.0 -0.58 143226.0 -437000.0 -0.61 -0.8444 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G01 compound treatment 756572.0 175000.0 0.25 858905.0 279000.0 0.39 0.4505 0.9767 2071082 Maybridge1_003477 COc1ccc(/C=C/2\CC/C(=C\c3ccc(OC)cc3)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G02 compound treatment 736137.0 154000.0 0.22 889501.0 309000.0 0.43 0.4601 0.9509 2071083 Maybridge1_003478 Cc1nc(cs1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G03 compound treatment 804980.0 223000.0 0.32 936174.0 356000.0 0.5 0.5754 0.9767 2071084 Maybridge1_003479 CN1C/C(=C\c2ccccc2)/C(=O)\C(=C\c3ccccc3)\C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G04 compound treatment 793726.0 212000.0 0.3 901745.0 321000.0 0.45 0.5301 0.9813 2071085 Maybridge1_003480 Clc1ccc(Cc2nc(cs2)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G05 compound treatment 820592.0 239000.0 0.34 956208.0 376000.0 0.52 0.6109 0.9779 1494940 Maybridge1_003481 CNc1ccccc1C(=O)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G06 compound treatment 808106.0 226000.0 0.32 956132.0 376000.0 0.52 0.5982 0.9726 2071086 Maybridge1_003482 S=C1NCCCN1C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G07 compound treatment 823180.0 241000.0 0.34 976328.0 396000.0 0.55 0.6333 0.9738 2071087 Maybridge1_003483 Clc1ccccc1CSC2=NCCN2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G08 compound treatment 845030.0 263000.0 0.37 937128.0 357000.0 0.5 0.6166 0.9901 1632209 Maybridge1_003484 CCC(CO)N1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G09 compound treatment 865434.0 284000.0 0.4 961559.0 381000.0 0.53 0.6612 0.9907 2071088 Maybridge1_003485 Clc1ccccc1CSc2nc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G10 compound treatment 842728.0 261000.0 0.37 949010.0 369000.0 0.51 0.626 0.9872 2071089 Maybridge1_003486 Cc1cc(C)c(CSc2ccccn2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G11 compound treatment 865775.0 284000.0 0.4 914461.0 334000.0 0.47 0.6151 0.9974 2071090 Maybridge1_003487 Clc1ccc(cc1)C2=NNC(N2)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G12 compound treatment 873623.0 292000.0 0.41 952662.0 372000.0 0.52 0.6607 0.9938 2071091 Maybridge1_003488 CSC1=NCN(Cc2ccccc2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G13 compound treatment 906888.0 325000.0 0.46 980491.0 400000.0 0.56 0.7216 0.9956 2071092 Maybridge1_003489 CNC(=S)NN=C1CCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G14 compound treatment 843009.0 261000.0 0.37 920985.0 341000.0 0.48 0.5987 0.9926 2071093 Maybridge1_003490 CCCCCCCCCCCCN1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G15 compound treatment 914418.0 333000.0 0.47 1012380.0 432000.0 0.6 0.7606 0.9928 1017701 Maybridge1_003491 CSc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G16 compound treatment 867033.0 285000.0 0.41 982917.0 403000.0 0.56 0.6839 0.9872 1329134 Maybridge1_003492 Cc1nn(Cc2ccccc2Cl)c(=N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G17 compound treatment 927122.0 345000.0 0.49 1048309.0 468000.0 0.65 0.8088 0.9902 1250043 Maybridge1_003493 Clc1ccc(cc1)C2Nc3ccccc3-c4nc5ccccc5n24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G18 compound treatment 906716.0 325000.0 0.46 910211.0 330000.0 0.46 0.6521 1.0 1231206 Maybridge1_003494 COC(=O)c1ccccc1NC(=S)N(N)CCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G19 compound treatment 937292.0 355000.0 0.51 1029938.0 450000.0 0.63 0.8009 0.9943 2071094 Maybridge1_003495 N1C(Oc2ccccc12)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G20 compound treatment 897896.0 316000.0 0.45 978732.0 398000.0 0.56 0.7108 0.9945 1245464 Maybridge1_003496 Clc1cccc(c1)C(=O)NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G21 compound treatment 909260.0 327000.0 0.47 929863.0 350000.0 0.49 0.674 0.9997 2071095 Maybridge1_003497 CSC1=NCCN1S(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G22 compound treatment 875921.0 294000.0 0.42 970226.0 390000.0 0.54 0.6803 0.9916 1370776 Maybridge1_003498 Clc1ccccc1C(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G23 mock treatment 925054.0 343000.0 0.49 979835.0 400000.0 0.56 0.7392 0.9978 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 G24 mock treatment 175968.0 -406000.0 -0.58 170740.0 -410000.0 -0.57 -0.812 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H01 compound treatment 787080.0 205000.0 0.29 816594.0 236000.0 0.33 0.4395 0.9982 2071096 Maybridge1_003499 Nc1ccccc1C(=O)N/N=C/c2cc(Br)ccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H02 compound treatment 754987.0 173000.0 0.25 860596.0 280000.0 0.39 0.4506 0.9752 2071097 Maybridge1_003500 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H03 compound treatment 796107.0 214000.0 0.3 895664.0 315000.0 0.44 0.5265 0.9839 2071098 Maybridge1_003501 CC(=O)Nc1ccc(F)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H04 compound treatment 808851.0 227000.0 0.32 907730.0 327000.0 0.46 0.5512 0.9856 2071099 Maybridge1_003502 COc1cc(/C=N/c2ccc(F)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H05 compound treatment 840001.0 258000.0 0.37 896338.0 316000.0 0.44 0.5713 0.9959 2071100 Maybridge1_003503 COC(=O)c1cc(ccc1Sc2ccccc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H06 compound treatment 859807.0 278000.0 0.4 881021.0 301000.0 0.42 0.5761 0.9996 2071101 Maybridge1_003504 [O-][N+](=O)c1ccccc1SCC(=O)NNC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H07 compound treatment 870309.0 289000.0 0.41 911328.0 331000.0 0.46 0.6166 0.9983 2071102 Maybridge1_003505 FC(F)(F)c1cc(cc(c1)S(=O)(=O)c2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H08 compound treatment 871054.0 289000.0 0.41 938549.0 358000.0 0.5 0.6442 0.9953 1464611 Maybridge1_003506 Oc1ccccc1c2nc3ccccc3c(=O)[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H09 compound treatment 917886.0 336000.0 0.48 971651.0 391000.0 0.55 0.7239 0.9978 1412023 Maybridge1_003507 O=C(CCN1CCOCC1)c2ccc3OCCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H10 compound treatment 891727.0 310000.0 0.44 934534.0 354000.0 0.49 0.661 0.9984 2071103 Maybridge1_003508 CC1(C)N/C(=N/c2cc(Cl)c(Cl)cc2Cl)/SC1=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H11 compound treatment 898106.0 316000.0 0.45 938567.0 358000.0 0.5 0.6714 0.9986 2071104 Maybridge1_003509 CC1(C)C2CCC1(C)/C(=N/Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])/C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H12 compound treatment 865130.0 283000.0 0.4 922235.0 342000.0 0.48 0.6221 0.9965 2071105 Maybridge1_003510 Clc1ccccc1NC(=S)N(CCC#N)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H13 compound treatment 1238962.0 657000.0 0.93 1322809.0 743000.0 1.04 1.3931 0.9987 1284432 Maybridge1_003511 COc1ccc(CC(=C(C#N)C#N)C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H14 compound treatment 878471.0 297000.0 0.42 954225.0 374000.0 0.52 0.6671 0.9945 1510455 Maybridge1_003512 COc1ccccc1NC(=S)NCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H15 compound treatment 960384.0 379000.0 0.54 1002419.0 422000.0 0.59 0.797 0.999 2071106 Maybridge1_003513 Clc1ccc(cc1Cl)C2NN=C3C2N4CCC3CC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H16 compound treatment 864241.0 282000.0 0.4 958895.0 379000.0 0.53 0.6574 0.9909 1737399 Maybridge1_003514 CCOC(=O)c1ccc(NC(=S)NCc2cccnc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H17 compound treatment 955073.0 373000.0 0.53 1006724.0 426000.0 0.59 0.7959 0.9984 2071107 Maybridge1_003515 Cc1cccc(C)c1/N=C\2/NC(C)(C)C(=C)S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H18 compound treatment 886024.0 304000.0 0.43 968775.0 388000.0 0.54 0.689 0.9938 2071108 Maybridge1_003516 S=C(Nc1cccc2ccccc12)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H19 compound treatment 917215.0 335000.0 0.48 985325.0 405000.0 0.56 0.7367 0.9965 1646121 Maybridge1_003517 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C(C)(C)C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H20 compound treatment 912336.0 331000.0 0.47 936420.0 356000.0 0.5 0.6836 0.9996 1236412 Maybridge1_003518 Cc1onc(c1C(=O)Nc2ccc3OCOc3c2)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H21 compound treatment 976279.0 394000.0 0.56 906443.0 326000.0 0.45 0.7183 0.9946 2071109 Maybridge1_003519 COc1cc(cc(OC)c1OC)C(=O)N/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H22 compound treatment 921680.0 340000.0 0.48 960001.0 380000.0 0.53 0.7163 0.999 2071110 Maybridge1_003520 Clc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H23 mock treatment 955707.0 374000.0 0.53 964442.0 384000.0 0.54 0.7548 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 H24 mock treatment 160692.0 -421000.0 -0.6 169943.0 -410000.0 -0.57 -0.8281 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I01 compound treatment 758308.0 177000.0 0.25 852753.0 272000.0 0.38 0.4462 0.9797 2071111 Maybridge1_003521 COc1ccc(/C=C/2\CC/C(=C\c3ccc(OC)c(OC)c3)/C2=O)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I02 compound treatment 771214.0 189000.0 0.27 880956.0 301000.0 0.42 0.487 0.9771 2071112 Maybridge1_003522 Clc1ccc(cc1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I03 compound treatment 808011.0 226000.0 0.32 955735.0 375000.0 0.52 0.5977 0.9726 1013283 Maybridge1_003523 CCOC(=O)CSc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I04 compound treatment 798252.0 216000.0 0.31 973317.0 393000.0 0.55 0.6053 0.9628 2071113 Maybridge1_003524 Cc1ccc(CC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I05 compound treatment 853862.0 272000.0 0.39 883301.0 303000.0 0.42 0.5724 0.999 1461883 Maybridge1_003525 CNc1ccc(Cl)cc1C(=O)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I06 compound treatment 758516.0 177000.0 0.25 947696.0 367000.0 0.51 0.54 0.9462 2071114 Maybridge1_003526 CC(=O)Nc1ccc(cc1)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I07 compound treatment 878672.0 297000.0 0.42 984440.0 404000.0 0.56 0.6971 0.9899 1030955 Maybridge1_003527 COC(=O)c1ccccc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I08 compound treatment 836096.0 254000.0 0.36 982407.0 402000.0 0.56 0.6523 0.9775 2071115 Maybridge1_003528 Cc1cc(C)c(CSC2=NCCN2)c(C)c1CSC3=NCCN3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I09 compound treatment 867720.0 286000.0 0.41 875707.0 295000.0 0.41 0.5789 1.0 2071116 Maybridge1_003529 Nc1ccccc1C(=O)NNC(=O)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I10 compound treatment 872392.0 291000.0 0.41 978218.0 398000.0 0.56 0.6847 0.9894 2071117 Maybridge1_003530 Cc1cc(C)c(CSc2nccn2C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I11 compound treatment 889666.0 308000.0 0.44 985024.0 405000.0 0.56 0.7087 0.9921 2071118 Maybridge1_003531 Clc1ccc(cc1)C2=NNC(N2)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I12 compound treatment 887719.0 306000.0 0.44 969544.0 389000.0 0.54 0.6915 0.994 1397307 Maybridge1_003532 CC(C)c1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I13 compound treatment 868507.0 287000.0 0.41 988572.0 408000.0 0.57 0.691 0.9866 2071119 Maybridge1_003533 CNC(=S)NN=C1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I14 compound treatment 869281.0 287000.0 0.41 1006272.0 426000.0 0.59 0.7092 0.9834 2071120 Maybridge1_003534 CN(N)C(=S)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I15 compound treatment 946952.0 365000.0 0.52 1002355.0 422000.0 0.59 0.7834 0.998 1565188 Maybridge1_003535 CN(C)c1ccc(cc1)C2Nc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I16 compound treatment 866932.0 285000.0 0.41 1011510.0 431000.0 0.6 0.712 0.9816 1604536 Maybridge1_003536 CNc1ccccc1C(=O)NC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I17 compound treatment 929040.0 347000.0 0.49 1038500.0 458000.0 0.64 0.8011 0.9919 1340303 Maybridge1_003537 COc1ccc(CNc2ccccc2c3nc4ccccc4[nH]3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I18 compound treatment 896513.0 315000.0 0.45 1010959.0 431000.0 0.6 0.7412 0.9895 2071121 Maybridge1_003538 Clc1ccc(NC(=O)CC2NCCN(Cc3ccccc3)C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I19 compound treatment 917373.0 336000.0 0.48 1014166.0 434000.0 0.61 0.7653 0.9931 2071122 Maybridge1_003539 CN1CNC(=NC1)SCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I20 compound treatment 903137.0 321000.0 0.46 1018123.0 438000.0 0.61 0.7549 0.9898 1470325 Maybridge1_003540 Clc1ccc(cc1)C(=C)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I21 compound treatment 926935.0 345000.0 0.49 1027166.0 447000.0 0.62 0.7878 0.993 2071123 Maybridge1_003541 CSC1=NCCN1S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I22 compound treatment 931424.0 350000.0 0.5 947463.0 367000.0 0.51 0.7137 0.9999 2071124 Maybridge1_003542 OC(=O)CCc1nc(no1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I23 mock treatment 940340.0 359000.0 0.51 1003220.0 423000.0 0.59 0.7776 0.9974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 I24 mock treatment 201879.0 -380000.0 -0.54 157978.0 -422000.0 -0.59 -0.7985 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J01 compound treatment 780975.0 199000.0 0.28 830201.0 250000.0 0.35 0.4468 0.9947 2071125 Maybridge1_003543 NC(=O)N/N=C/1\CCOc2ccc3ccccc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J02 compound treatment 780138.0 198000.0 0.28 838644.0 258000.0 0.36 0.4542 0.9927 2071126 Maybridge1_003544 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J03 compound treatment 820216.0 238000.0 0.34 948972.0 369000.0 0.51 0.6033 0.9796 1049119 Maybridge1_003545 CC(C)c1ccc(NC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J04 compound treatment 800250.0 218000.0 0.31 943049.0 363000.0 0.51 0.5774 0.9726 2071127 Maybridge1_003546 Nc1ccccc1Sc2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J05 compound treatment 843767.0 262000.0 0.37 871007.0 291000.0 0.41 0.5501 0.9991 2071128 Maybridge1_003547 COC(=O)c1cc(ccc1Sc2ccc(Cl)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J06 compound treatment 837111.0 255000.0 0.36 941249.0 361000.0 0.5 0.6127 0.9871 2071129 Maybridge1_003548 [O-][N+](=O)c1ccccc1SCc2nnc(S)n2c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J07 compound treatment 894163.0 312000.0 0.44 957725.0 377000.0 0.53 0.6863 0.9964 1303668 Maybridge1_003549 CCOC(=O)c1sc2ccc(NC(=O)c3ccccc3Cl)cc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J08 compound treatment 888839.0 307000.0 0.44 901982.0 322000.0 0.45 0.626 0.9999 2071130 Maybridge1_003550 CCOC(=O)c1ccc(/N=C\2/NC(CC)(CC)C(=C)S2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J09 compound treatment 884603.0 303000.0 0.43 997498.0 417000.0 0.58 0.7159 0.989 1057159 Maybridge1_003551 Cc1ccc(C(=O)CCN2CCOCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J10 compound treatment 890445.0 309000.0 0.44 917014.0 337000.0 0.47 0.6424 0.9994 1378916 Maybridge1_003552 COc1cc(Cl)cc(OC)c1NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J11 compound treatment 914860.0 333000.0 0.47 912345.0 332000.0 0.46 0.6624 0.9999 1652494 Maybridge1_003553 Cc1onc(c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J12 compound treatment 883091.0 301000.0 0.43 931954.0 352000.0 0.49 0.6498 0.9977 1192076 Maybridge1_003554 CC(C)c1ccc(NC(=S)Nc2c(C)cccc2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J13 compound treatment 924486.0 343000.0 0.49 964124.0 384000.0 0.54 0.7231 0.9989 2071131 Maybridge1_003555 COc1ccc(cc1)C(CCC#N)(CCC#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J14 compound treatment 896837.0 315000.0 0.45 976821.0 397000.0 0.55 0.7079 0.9945 1213155 Maybridge1_003556 COc1cccc(NC(=S)NCc2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J15 compound treatment 902141.0 320000.0 0.46 975400.0 395000.0 0.55 0.7118 0.9955 2071132 Maybridge1_003557 C1Oc2ccc(cc2O1)C3NN=C4C3N5CCC4CC5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J16 compound treatment 899955.0 318000.0 0.45 959963.0 380000.0 0.53 0.6944 0.9969 2071133 Maybridge1_003558 Clc1ccc(NC(=S)NCc2cccnc2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J17 compound treatment 934416.0 353000.0 0.5 995677.0 415000.0 0.58 0.7642 0.9974 1081790 Maybridge1_003559 FC(F)(F)c1cccc(NC(=O)COc2cc(Cl)c(Cl)cc2Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J18 compound treatment 906546.0 325000.0 0.46 931389.0 351000.0 0.49 0.6728 0.9996 1736870 Maybridge1_003560 Cc1onc(c1C(=O)N2CCOCC2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J19 compound treatment 962519.0 381000.0 0.54 906930.0 327000.0 0.46 0.705 0.9963 1568250 Maybridge1_003561 Clc1ccc(Cl)c(c1)S(=O)(=O)NC2(CCCCC2)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J20 compound treatment 936392.0 355000.0 0.5 930168.0 350000.0 0.49 0.7016 0.9999 1226028 Maybridge1_003562 Cc1onc(c1C(=O)Nc2ccc(C)c(F)c2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J21 compound treatment 960098.0 378000.0 0.54 946191.0 366000.0 0.51 0.7413 0.9997 2071134 Maybridge1_003563 ClC(Cl)C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J22 compound treatment 900064.0 318000.0 0.45 934805.0 355000.0 0.49 0.6697 0.999 2071135 Maybridge1_003564 Cc1ccc(Cl)cc1NC(=S)N(CCC#N)/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J23 mock treatment 915319.0 334000.0 0.47 971104.0 391000.0 0.55 0.7208 0.9976 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 J24 mock treatment 152886.0 -429000.0 -0.61 140837.0 -439000.0 -0.61 -0.8647 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K01 compound treatment 1491523.0 910000.0 1.29 1534960.0 955000.0 1.33 1.8563 0.9999 1913140 Maybridge1_003565 O=C/1/C(=C/c2ccc3OCOc3c2)/CC\C1=C/c4ccc5OCOc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K02 compound treatment 735755.0 154000.0 0.22 877650.0 297000.0 0.41 0.4481 0.9554 2071136 Maybridge1_003566 Nc1nc(cs1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K03 compound treatment 794541.0 213000.0 0.3 904033.0 324000.0 0.45 0.5332 0.981 1344801 Maybridge1_003567 CNc1ccccc1C(=O)NC2CC(C)CC(C)(C)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K04 compound treatment 773934.0 192000.0 0.27 895556.0 315000.0 0.44 0.5041 0.9738 2071137 Maybridge1_003568 Clc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K05 compound treatment 880859.0 299000.0 0.43 996726.0 416000.0 0.58 0.7114 0.9883 2071138 Maybridge1_003569 CN1C/C(=C\c2ccco2)/C(=O)\C(=C\c3ccco3)\C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K06 compound treatment 809366.0 228000.0 0.32 898791.0 319000.0 0.44 0.5429 0.9879 1712799 Maybridge1_003570 OCCCN1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K07 compound treatment 840659.0 259000.0 0.37 964267.0 384000.0 0.54 0.639 0.9833 2071139 Maybridge1_003571 Clc1ccc(CSC2=NCCCN2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K08 compound treatment 837016.0 255000.0 0.36 879752.0 299000.0 0.42 0.552 0.9975 2071140 Maybridge1_003572 Cc1cc(C)c(CSC(=N)N)c(C)c1CSC(=N)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K09 compound treatment 867098.0 285000.0 0.41 981658.0 401000.0 0.56 0.6827 0.9875 1035818 Maybridge1_003573 Clc1ccc(CSc2nc3ccccc3[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K10 compound treatment 836559.0 255000.0 0.36 912439.0 332000.0 0.46 0.5838 0.9926 2071141 Maybridge1_003574 CC(C)(C)N1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K11 compound treatment 850230.0 268000.0 0.38 935938.0 356000.0 0.5 0.6207 0.9916 2071142 Maybridge1_003575 CNC(=S)N/N=C(\C)/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K12 compound treatment 834599.0 253000.0 0.36 907535.0 327000.0 0.46 0.5769 0.993 1074367 Maybridge1_003576 CCOC(=O)c1c(NC(=O)C)sc2CCCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K13 compound treatment 897437.0 316000.0 0.45 944553.0 364000.0 0.51 0.6766 0.9981 2071143 Maybridge1_003577 CNC(=S)NN=C1CCCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K14 compound treatment 876128.0 294000.0 0.42 920432.0 340000.0 0.47 0.6314 0.998 2071144 Maybridge1_003578 COC(=O)c1ccccc1NC(=S)N(C)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K15 compound treatment 874588.0 293000.0 0.42 924160.0 344000.0 0.48 0.6336 0.9975 1181884 Maybridge1_003579 CN(C)c1ccc(cc1)C2Nc3cc(Cl)ccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K16 compound treatment 845303.0 263000.0 0.37 999771.0 419000.0 0.59 0.6787 0.9768 1597144 Maybridge1_003580 CNc1ccc(Cl)cc1C(=O)NC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K17 compound treatment 861710.0 280000.0 0.4 907713.0 327000.0 0.46 0.6044 0.9977 1090814 Maybridge1_003581 Nc1ccc(Cl)cc1c2nc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K18 compound treatment 875953.0 294000.0 0.42 981857.0 402000.0 0.56 0.6918 0.9897 2071145 Maybridge1_003582 NNC(=O)CC1NCCN(Cc2ccccc2)C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K19 compound treatment 902166.0 320000.0 0.46 1012528.0 432000.0 0.6 0.7484 0.9905 2071146 Maybridge1_003583 CN1CNC(=NC1)SCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K20 compound treatment 897629.0 316000.0 0.45 962230.0 382000.0 0.53 0.6943 0.9964 1226276 Maybridge1_003584 c1nc(c2ccccc2)n3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K21 compound treatment 941296.0 359000.0 0.51 1020059.0 440000.0 0.61 0.7952 0.9959 2071147 Maybridge1_003585 COCCCN1CNC(=NC1)SCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K22 compound treatment 884856.0 303000.0 0.43 929398.0 349000.0 0.49 0.649 0.9981 1650617 Maybridge1_003586 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K23 mock treatment 940982.0 359000.0 0.51 973169.0 393000.0 0.55 0.7486 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 K24 mock treatment 144305.0 -437000.0 -0.62 154552.0 -426000.0 -0.59 -0.8598 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L01 compound treatment 758606.0 177000.0 0.25 804900.0 225000.0 0.31 0.3993 0.9941 2071148 Maybridge1_003587 COc1ccc(CCNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L02 compound treatment 771398.0 190000.0 0.27 851219.0 271000.0 0.38 0.4579 0.9863 2071149 Maybridge1_003588 Fc1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L03 compound treatment 804356.0 223000.0 0.32 900822.0 321000.0 0.45 0.5399 0.9857 2071150 Maybridge1_003589 [O-][N+](=O)c1cc(F)ccc1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L04 compound treatment 787562.0 206000.0 0.29 870763.0 290000.0 0.41 0.4934 0.9872 2071151 Maybridge1_003590 Nc1ccccc1Sc2ccc(Cl)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L05 compound treatment 818525.0 237000.0 0.34 937911.0 358000.0 0.5 0.5907 0.9817 2071152 Maybridge1_003591 CC(=O)c1cc2cc(Cl)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L06 compound treatment 790211.0 208000.0 0.3 914410.0 334000.0 0.47 0.5391 0.9761 2071153 Maybridge1_003592 [O-][N+](=O)c1ccccc1SCC(=O)NNC(=S)NC2CC3CC2C=C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L07 compound treatment 851482.0 270000.0 0.38 955451.0 375000.0 0.52 0.6412 0.9883 2071154 Maybridge1_003593 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L08 compound treatment 817832.0 236000.0 0.34 804651.0 224000.0 0.31 0.4586 0.9994 1150396 Maybridge1_003594 O=C1N2CCNC2(c3ccccc13)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L09 compound treatment 864859.0 283000.0 0.4 904541.0 324000.0 0.45 0.6044 0.9983 1562697 Maybridge1_003595 CCc1cc2c(cc1C(=O)CCN3CCCC3)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L10 compound treatment 837589.0 256000.0 0.36 907201.0 327000.0 0.46 0.5796 0.9937 1382047 Maybridge1_003596 CSc1cccc(NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L11 compound treatment 877952.0 296000.0 0.42 932611.0 352000.0 0.49 0.6453 0.997 1599520 Maybridge1_003597 CC(NC1(C#N)C2CC3CC(C2)CC1C3)c4ccc(C)cc4C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L12 compound treatment 873837.0 292000.0 0.42 930393.0 350000.0 0.49 0.6389 0.9968 2071155 Maybridge1_003598 CC(C)c1ccc(NC(=S)Nc2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L13 compound treatment 846600.0 265000.0 0.38 906044.0 326000.0 0.45 0.5875 0.9956 1678992 Maybridge1_003599 Cc1onc(c1C(=O)N2CCCN3C2c4ccccc4C3=O)c5ccccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L14 compound treatment 896113.0 314000.0 0.45 919240.0 339000.0 0.47 0.6503 0.9996 1253884 Maybridge1_003600 CCOC(=O)c1ccc(NC(=S)NCc2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L15 compound treatment 913268.0 331000.0 0.47 958648.0 378000.0 0.53 0.7065 0.9984 1387935 Maybridge1_003601 O=C1N2CCCN(C2c3ccccc13)S(=O)(=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L16 compound treatment 892544.0 311000.0 0.44 921847.0 342000.0 0.48 0.6493 0.9993 2071156 Maybridge1_003602 FC(F)(F)c1cccc(NC(=S)N2CCOCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L17 compound treatment 892288.0 310000.0 0.44 959238.0 379000.0 0.53 0.6859 0.996 2071157 Maybridge1_003603 [O-][N+](=O)c1cccc(/C=C/c2ccccn2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L18 compound treatment 890979.0 309000.0 0.44 973072.0 393000.0 0.55 0.6983 0.9941 1370915 Maybridge1_003604 Cc1onc(c1C(=O)N2CCCCC2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L19 compound treatment 929551.0 348000.0 0.49 948879.0 369000.0 0.51 0.7132 0.9998 1629964 Maybridge1_003605 Cc1ccc(cc1)S(=O)(=O)Nc2cccc(CCc3ccccn3)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L20 compound treatment 928879.0 347000.0 0.49 892898.0 313000.0 0.44 0.6573 0.9981 2071158 Maybridge1_003606 CSc1cccc(NC(=O)c2c(C)onc2c3ccccc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L21 compound treatment 960698.0 379000.0 0.54 969982.0 390000.0 0.54 0.7653 1.0 1731713 Maybridge1_003607 Clc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L22 compound treatment 928327.0 347000.0 0.49 924416.0 344000.0 0.48 0.6878 0.9999 2071159 Maybridge1_003608 Cc1ccc(NC(=S)NCc2cccnc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L23 mock treatment 920397.0 339000.0 0.48 926651.0 346000.0 0.48 0.6821 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 L24 mock treatment 145405.0 -436000.0 -0.62 155023.0 -425000.0 -0.59 -0.8582 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M01 compound treatment 751672.0 170000.0 0.24 822948.0 243000.0 0.34 0.4101 0.9863 2071160 Maybridge1_003609 Clc1ccc(/C=C/2\CC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M02 compound treatment 724391.0 143000.0 0.2 843958.0 264000.0 0.37 0.4034 0.9606 1024036 Maybridge1_003610 Clc1ccc(cc1)C2=CSC3=NCCN23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M03 compound treatment 796153.0 214000.0 0.3 953744.0 373000.0 0.52 0.5839 0.9674 2071161 Maybridge1_003611 CC(C)c1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M04 compound treatment 764412.0 183000.0 0.26 820599.0 240000.0 0.34 0.4206 0.992 2071162 Maybridge1_003612 Clc1ccc(cc1)c2csc(Cc3ccccc3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M05 compound treatment 804564.0 223000.0 0.32 927835.0 348000.0 0.48 0.5668 0.9787 1013280 Maybridge1_003613 OC(=O)CSc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M06 compound treatment 784288.0 202000.0 0.29 888355.0 308000.0 0.43 0.5074 0.981 2071163 Maybridge1_003614 Clc1ccccc1CSC2=NCCCN2C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M07 compound treatment 830458.0 249000.0 0.35 962201.0 382000.0 0.53 0.6267 0.9802 2071164 Maybridge1_003615 Clc1ccccc1CSC2=NCCCN2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M08 compound treatment 785128.0 203000.0 0.29 871289.0 291000.0 0.41 0.4915 0.9862 1218071 Maybridge1_003616 NNC(=O)c1nc2ccccc2c(=O)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M09 compound treatment 834844.0 253000.0 0.36 908798.0 329000.0 0.46 0.5784 0.9929 1328191 Maybridge1_003617 Clc1ccc(cc1)c2csc(=N)n2c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M10 compound treatment 839227.0 257000.0 0.37 891382.0 311000.0 0.43 0.5657 0.9964 2071165 Maybridge1_003618 Clc1ccc(cc1)C2=NC(N=C(S2)c3ccc(Cl)cc3)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M11 compound treatment 870920.0 289000.0 0.41 925923.0 346000.0 0.48 0.6316 0.9969 2071166 Maybridge1_003619 CNC(=S)N/N=C(\C)/c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M12 compound treatment 838928.0 257000.0 0.37 937583.0 357000.0 0.5 0.6109 0.9884 1493034 Maybridge1_003620 COC(=O)c1ccccc1NC(=S)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M13 compound treatment 889247.0 307000.0 0.44 894495.0 314000.0 0.44 0.619 1.0 2071167 Maybridge1_003621 CC1CN(CC(C)O1)C(=N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M14 compound treatment 848273.0 266000.0 0.38 970881.0 391000.0 0.54 0.6532 0.9843 1677509 Maybridge1_003622 Cc1c(Cl)cccc1NC(=S)N(N)CCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M15 compound treatment 909903.0 328000.0 0.47 983338.0 403000.0 0.56 0.7274 0.9957 1272679 Maybridge1_003623 OC(=O)CCCc1nc(no1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M16 compound treatment 855253.0 273000.0 0.39 949197.0 369000.0 0.51 0.6388 0.9905 2071168 Maybridge1_003624 FC(F)(F)c1nn2cc(nc2s1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M17 compound treatment 888994.0 307000.0 0.44 984721.0 404000.0 0.56 0.7078 0.992 2071169 Maybridge1_003625 Clc1ccccc1C2Nc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M18 compound treatment 870214.0 288000.0 0.41 944535.0 364000.0 0.51 0.6492 0.9944 1730982 Maybridge1_003626 Nc1ccc(Cl)cc1C(=O)NCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M19 compound treatment 911845.0 330000.0 0.47 948981.0 369000.0 0.51 0.6955 0.999 2071170 Maybridge1_003627 CCN1CNC(=NC1)SCc2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M20 compound treatment 874675.0 293000.0 0.42 940754.0 360000.0 0.5 0.65 0.9956 2071171 Maybridge1_003628 [O-][N+](=O)c1ccccc1c2ncc3ccccn23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M21 compound treatment 909654.0 328000.0 0.47 965675.0 385000.0 0.54 0.7098 0.9975 2071172 Maybridge1_003629 CCN1CNC(=NC1)SCc2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M22 compound treatment 873947.0 292000.0 0.42 947277.0 367000.0 0.51 0.6557 0.9946 2071173 Maybridge1_003630 CNc1ccc(Cl)cc1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M23 mock treatment 924771.0 343000.0 0.49 951984.0 372000.0 0.52 0.7115 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 M24 mock treatment 347305.0 -234000.0 -0.33 740518.0 160000.0 0.22 -0.0778 -0.1937 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N01 compound treatment 772256.0 190000.0 0.27 833188.0 253000.0 0.35 0.4409 0.9915 2071174 Maybridge1_003631 Cc1cccc2CCCN(C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N02 compound treatment 768892.0 187000.0 0.27 851063.0 271000.0 0.38 0.4552 0.9853 2071175 Maybridge1_003632 COc1cc(NS(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N03 compound treatment 797191.0 215000.0 0.31 921416.0 341000.0 0.48 0.553 0.9773 2071176 Maybridge1_003633 Nc1ccccc1C(=O)NCCCNC(=O)c2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N04 compound treatment 799415.0 218000.0 0.31 882485.0 302000.0 0.42 0.5169 0.9885 2071177 Maybridge1_003634 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2Sc3ccc(Cl)cc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N05 compound treatment 819561.0 238000.0 0.34 888020.0 308000.0 0.43 0.5426 0.993 1180989 Maybridge1_003635 Clc1ccc2oc(cc2c1)C(=O)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N06 compound treatment 801134.0 219000.0 0.31 868789.0 289000.0 0.4 0.5051 0.9921 2071178 Maybridge1_003636 NS(=O)(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N07 compound treatment 833756.0 252000.0 0.36 859143.0 279000.0 0.39 0.5284 0.9992 2071179 Maybridge1_003637 N#CCCN/N=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N08 compound treatment 847388.0 266000.0 0.38 848729.0 268000.0 0.37 0.5318 1.0 2071180 Maybridge1_003638 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCN3C(=O)c4ccccc4C23c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N09 compound treatment 865418.0 284000.0 0.4 908276.0 328000.0 0.46 0.6087 0.998 1699549 Maybridge1_003639 O=C(CCN1CCCC1)c2ccc3ccccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N10 compound treatment 860053.0 278000.0 0.4 967378.0 387000.0 0.54 0.6616 0.9883 1490310 Maybridge1_003640 CCOC(=O)c1ccc(NC(=S)N2CCN3C(=O)c4ccccc4C23c5ccccc5)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N11 compound treatment 882994.0 301000.0 0.43 965040.0 385000.0 0.54 0.6823 0.9938 1596245 Maybridge1_003641 Cc1onc(c1C(=O)N(CCC#N)Cc2ccccc2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N12 compound treatment 852587.0 271000.0 0.39 934752.0 354000.0 0.49 0.6219 0.9924 2071181 Maybridge1_003642 Clc1ccccc1NC(=S)NCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N13 compound treatment 872447.0 291000.0 0.41 969300.0 389000.0 0.54 0.6759 0.991 1193847 Maybridge1_003643 Cc1onc(c1C(=O)NC(C)(C)CCO)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N14 compound treatment 841444.0 260000.0 0.37 903881.0 324000.0 0.45 0.5802 0.995 1545358 Maybridge1_003644 Cc1cccc(NC(=S)NCc2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N15 compound treatment 938093.0 356000.0 0.51 916779.0 337000.0 0.47 0.6901 0.9993 2071182 Maybridge1_003645 FC(F)(F)c1cccc(/N=C/2\NC3(CCCCC3)C(=C)S2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N16 compound treatment 884176.0 302000.0 0.43 949532.0 369000.0 0.52 0.6682 0.996 2071183 Maybridge1_003646 COc1cccc(NC(=S)N2CCOCC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N17 compound treatment 919057.0 337000.0 0.48 958031.0 378000.0 0.53 0.7117 0.9989 2071184 Maybridge1_003647 CC(C)c1ccc(/C=N/c2ccc(cc2)C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N18 compound treatment 892205.0 310000.0 0.44 960556.0 380000.0 0.53 0.6872 0.9958 2071185 Maybridge1_003648 CC1CN(CC(C)O1)C(=S)Nc2ccccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N19 compound treatment 915779.0 334000.0 0.47 976416.0 396000.0 0.55 0.7265 0.9972 1215090 Maybridge1_003649 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2cccc(CCc3ccccn3)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N20 compound treatment 894189.0 312000.0 0.44 879632.0 299000.0 0.42 0.6093 0.9995 2071186 Maybridge1_003650 CCCCNC(=S)N(CCC#N)C1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N21 compound treatment 943759.0 362000.0 0.51 990804.0 411000.0 0.57 0.7688 0.9986 1734074 Maybridge1_003651 Cc1onc(c1C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N22 compound treatment 886341.0 305000.0 0.43 956208.0 376000.0 0.52 0.677 0.9955 2071187 Maybridge1_003652 Cc1c(Cl)cccc1NC(=S)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N23 mock treatment 932422.0 351000.0 0.5 954157.0 374000.0 0.52 0.7213 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 N24 mock treatment 689757.0 108000.0 0.15 310917.0 -269000.0 -0.38 -0.1571 -0.3871 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O01 compound treatment 763930.0 182000.0 0.26 814604.0 234000.0 0.33 0.4142 0.9934 2071188 Maybridge1_003653 O=C/1/C(=C/c2cccc3ccccc23)/CC\C1=C/c4cccc5ccccc45 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O02 compound treatment 717096.0 135000.0 0.19 825770.0 245000.0 0.34 0.3781 0.9628 2071189 Maybridge1_003654 Clc1ccc(cc1)C2=CSC3=NCCCN23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O03 compound treatment 755135.0 173000.0 0.25 907740.0 327000.0 0.46 0.4972 0.9581 1508216 Maybridge1_003655 CNc1ccccc1C(=O)NCCc2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O04 compound treatment 740961.0 159000.0 0.23 863791.0 284000.0 0.4 0.4396 0.965 2071190 Maybridge1_003656 COc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O05 compound treatment 776224.0 194000.0 0.28 872502.0 292000.0 0.41 0.4837 0.9821 2071191 Maybridge1_003657 CN1C/C(=C\c2ccccc2Cl)/C(=O)\C(=C\c3ccccc3Cl)\C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O06 compound treatment 768624.0 187000.0 0.27 860780.0 281000.0 0.39 0.4645 0.9822 2071192 Maybridge1_003658 Clc1ccc(CSC2=NCCCN2C3CCCCC3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O07 compound treatment 800078.0 218000.0 0.31 928325.0 348000.0 0.49 0.5627 0.9767 2071193 Maybridge1_003659 Cc1ccc(CSC2=NCCCN2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O08 compound treatment 789745.0 208000.0 0.3 869266.0 289000.0 0.4 0.4941 0.9884 1482022 Maybridge1_003660 CCOC(=O)c1nc2sc3CCCCc3c2c(=O)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O09 compound treatment 817652.0 236000.0 0.34 883446.0 303000.0 0.42 0.5361 0.9934 1226826 Maybridge1_003661 Nc1ccccc1c2nc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O10 compound treatment 788913.0 207000.0 0.29 889935.0 310000.0 0.43 0.5136 0.9826 2071194 Maybridge1_003662 Clc1ccc(cc1)C2N=C(SC(=N2)c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O11 compound treatment 814143.0 232000.0 0.33 884271.0 304000.0 0.42 0.5334 0.9924 2071195 Maybridge1_003663 CNC(=S)N/N=C(\C)/c1ccc(OC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O12 compound treatment 806123.0 224000.0 0.32 886000.0 306000.0 0.43 0.5271 0.9898 2071196 Maybridge1_003664 CSC1=NCN(CN1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O13 compound treatment 856535.0 275000.0 0.39 908320.0 328000.0 0.46 0.5998 0.9969 2071197 Maybridge1_003665 C1Oc2ccc(cc2O1)C3Nc4ccccc4O3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O14 compound treatment 812991.0 231000.0 0.33 895739.0 315000.0 0.44 0.5436 0.9897 2071198 Maybridge1_003666 CN(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O15 compound treatment 850958.0 269000.0 0.38 931038.0 351000.0 0.49 0.6166 0.9926 2071199 Maybridge1_003667 COc1ccc(Br)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O16 compound treatment 815325.0 234000.0 0.33 912362.0 332000.0 0.46 0.5623 0.9867 2071200 Maybridge1_003668 Fc1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O17 compound treatment 870582.0 289000.0 0.41 952642.0 372000.0 0.52 0.6576 0.9932 2071201 Maybridge1_003669 Clc1ccc2OC(Nc2c1)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O18 compound treatment 854269.0 272000.0 0.39 915441.0 335000.0 0.47 0.6045 0.9957 1605476 Maybridge1_003670 Nc1ccccc1C(=O)NCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O19 compound treatment 881688.0 300000.0 0.43 960708.0 380000.0 0.53 0.6767 0.9941 2071202 Maybridge1_003671 CCN1CNC(=NC1)SCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O20 compound treatment 864929.0 283000.0 0.4 897246.0 317000.0 0.44 0.5973 0.9989 2071203 Maybridge1_003672 FC(F)(F)c1nnc(NC(=O)c2ccccc2NC(=O)c3ccccc3)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O21 compound treatment 885675.0 304000.0 0.43 932179.0 352000.0 0.49 0.6526 0.998 2071204 Maybridge1_003673 CCN1CNC(=NC1)SCc2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O22 compound treatment 839856.0 258000.0 0.37 896837.0 317000.0 0.44 0.5717 0.9958 2071205 Maybridge1_003674 O=C1NN(C(=S)Nc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O23 mock treatment 900695.0 319000.0 0.45 928611.0 348000.0 0.49 0.6642 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 O24 mock treatment 522433.0 -59400.0 -0.08 246942.0 -333000.0 -0.46 -0.3884 -0.8221 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P01 compound treatment 790735.0 209000.0 0.3 806318.0 226000.0 0.32 0.433 0.9996 1006990 Maybridge1_003675 CC(=O)Nc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P02 compound treatment 775475.0 194000.0 0.28 840542.0 260000.0 0.36 0.4514 0.9907 1253391 Maybridge1_003676 CCOC(=O)c1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P03 compound treatment 780805.0 199000.0 0.28 845281.0 265000.0 0.37 0.4615 0.9913 2071206 Maybridge1_003677 [O-][N+](=O)c1ccc(c(Cl)c1)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P04 compound treatment 786138.0 204000.0 0.29 861910.0 282000.0 0.39 0.4832 0.989 1561288 Maybridge1_003678 Clc1ccccc1C(=O)N(CCC#N)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P05 compound treatment 800376.0 219000.0 0.31 861972.0 282000.0 0.39 0.4976 0.9933 2071207 Maybridge1_003679 Oc1ccccc1/C=N/c2ccc(F)cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P06 compound treatment 794711.0 213000.0 0.3 849041.0 269000.0 0.37 0.4791 0.9944 2071208 Maybridge1_003680 NS(=O)(=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P07 compound treatment 816042.0 234000.0 0.33 829887.0 250000.0 0.35 0.4817 0.9998 1034875 Maybridge1_003681 N#CC1(CCCCC1)NC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P08 compound treatment 815099.0 233000.0 0.33 813135.0 233000.0 0.32 0.4642 0.9999 1017270 Maybridge1_003682 ClC(Cl)(Cl)C(=O)N1CCOCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P09 compound treatment 826625.0 245000.0 0.35 830436.0 250000.0 0.35 0.4929 1.0 1915614 Maybridge1_003683 C/C(=N\Nc1ccccc1)/c2ccc(cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P10 compound treatment 836667.0 255000.0 0.36 826930.0 247000.0 0.34 0.4995 0.9997 2071209 Maybridge1_003684 Fc1ccc(cc1F)N2C(=O)C3C4CC(C=C4)C3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P11 compound treatment 809617.0 228000.0 0.32 849977.0 270000.0 0.38 0.4951 0.9972 2071210 Maybridge1_003685 Cc1onc(c1C(=O)N(CCC#N)C2CCCCC2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P12 compound treatment 829580.0 248000.0 0.35 879391.0 299000.0 0.42 0.5441 0.9965 2071211 Maybridge1_003686 FC(F)(F)c1cccc(NC(=S)NCc2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P13 compound treatment 864867.0 283000.0 0.4 867470.0 287000.0 0.4 0.5679 1.0 2071212 Maybridge1_003687 COc1cc(/C=C\2/N3CCC(CC3)C2=O)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P14 compound treatment 845719.0 264000.0 0.38 861595.0 281000.0 0.39 0.5428 0.9998 1349974 Maybridge1_003688 COc1cccc(NC(=S)NCc2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P15 compound treatment 886927.0 305000.0 0.43 884993.0 305000.0 0.42 0.6073 0.9999 2071213 Maybridge1_003689 Clc1ccccc1/N=C/2\NC3(CCCCC3)C(=C)S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P16 compound treatment 863106.0 281000.0 0.4 892593.0 312000.0 0.44 0.5909 0.9991 2071214 Maybridge1_003690 COc1ccccc1NC(=S)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P17 compound treatment 886244.0 304000.0 0.43 904059.0 324000.0 0.45 0.6254 0.9998 2071215 Maybridge1_003691 OC(=O)c1ccc(/N=C/c2ccc3OCOc3c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P18 compound treatment 876549.0 295000.0 0.42 873654.0 293000.0 0.41 0.5857 0.9999 2071216 Maybridge1_003692 CC1CN(CC(C)O1)C(=S)Nc2cccc(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P19 compound treatment 880714.0 299000.0 0.43 876525.0 296000.0 0.41 0.5927 0.9999 1272372 Maybridge1_003693 COc1cc(cc(OC)c1OC)C(NCc2ccccc2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P20 compound treatment 883656.0 302000.0 0.43 891852.0 312000.0 0.43 0.6108 1.0 2071217 Maybridge1_003694 Cc1ccc(Cl)cc1NC(=S)NCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P21 compound treatment 879680.0 298000.0 0.42 891143.0 311000.0 0.43 0.6061 0.9999 1862715 Maybridge1_003695 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P22 compound treatment 886235.0 304000.0 0.43 892626.0 312000.0 0.44 0.6142 1.0 2071218 Maybridge1_003696 Cc1cccc(C)c1NC(=S)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P23 mock treatment 851032.0 269000.0 0.38 853612.0 273000.0 0.38 0.5403 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.551 P24 mock treatment 528970.0 -52800.0 -0.08 380194.0 -200000.0 -0.28 -0.2505 -0.8666 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A01 compound treatment 868094.0 289000.0 0.41 810154.0 210000.0 0.29 0.4974 0.9862 2071219 Maybridge1_003697 Cc1ccc(NC(=S)NCc2cccnc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A02 compound treatment 867782.0 288000.0 0.41 808187.0 208000.0 0.29 0.4952 0.9856 2071220 Maybridge1_003698 CCOC(=O)c1cnc(N)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A03 compound treatment 857959.0 279000.0 0.4 826060.0 226000.0 0.31 0.5029 0.9935 2071221 Maybridge1_003699 CSC(=C(C#N)c1ccc(Cl)cc1Cl)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A04 compound treatment 869955.0 291000.0 0.41 855344.0 255000.0 0.36 0.5439 0.9972 1658773 Maybridge1_003700 Cn1ccc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A05 compound treatment 875794.0 296000.0 0.42 880425.0 280000.0 0.39 0.5745 0.9993 2071222 Maybridge1_003701 Clc1ccc(NC(=O)Sc2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A06 compound treatment 905423.0 326000.0 0.46 900291.0 300000.0 0.42 0.6239 0.9987 2071223 Maybridge1_003702 CSc1cc(n[nH]1)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A07 compound treatment 920178.0 341000.0 0.48 872857.0 273000.0 0.38 0.6117 0.9928 568 Maybridge1_003703 COc1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A08 compound treatment 948180.0 369000.0 0.52 923550.0 323000.0 0.45 0.6898 0.9972 2071224 Maybridge1_003704 Cc1csc(C(=O)N)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A09 compound treatment 1060549.0 481000.0 0.68 955678.0 355000.0 0.5 0.8345 0.9875 2071225 Maybridge1_003705 NC1=C(C#N)C(C(C#N)C#N)c2cc(Br)cc(Br)c2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A10 compound treatment 929774.0 350000.0 0.5 894884.0 295000.0 0.41 0.643 0.9954 2071226 Maybridge1_003706 COC(=O)c1sc(Br)c(Br)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A11 compound treatment 1250078.0 671000.0 0.95 1039943.0 440000.0 0.61 1.1082 0.9772 2071227 Maybridge1_003707 COC(=O)C(C#N)C1C(=C(N)Oc2c(OC)cc(Br)cc12)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A12 compound treatment 947082.0 368000.0 0.52 923840.0 324000.0 0.45 0.689 0.9973 1192357 Maybridge1_003708 Cc1csc2ncnc(NCCc3ccc(Cl)cc3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A13 compound treatment 955092.0 376000.0 0.53 930706.0 330000.0 0.46 0.7038 0.9973 2071228 Maybridge1_003709 Clc1ccc(cc1)C(=O)NC2=CC3C(COC3=O)OC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A14 compound treatment 1009026.0 430000.0 0.61 993874.0 394000.0 0.55 0.8203 0.9986 2071229 Maybridge1_003710 Nc1cc(sc1C#N)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A15 compound treatment 1010907.0 432000.0 0.61 1011065.0 411000.0 0.57 0.8392 0.9994 1702696 Maybridge1_003711 COC(=O)c1sccc1NC(=O)CC(=O)Nc2ccsc2C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A16 compound treatment 951488.0 372000.0 0.53 938276.0 338000.0 0.47 0.7077 0.9983 1361943 Maybridge1_003712 COC(=O)Cn1nnc(n1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A17 compound treatment 958573.0 379000.0 0.54 951892.0 352000.0 0.49 0.7282 0.9989 1219663 Maybridge1_003713 CCOC(=O)c1c(C)csc1NC(=O)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A18 compound treatment 967048.0 388000.0 0.55 986493.0 386000.0 0.54 0.7709 0.9999 1116540 Maybridge1_003714 COC(=O)c1ccsc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A19 compound treatment 943888.0 365000.0 0.52 898891.0 299000.0 0.42 0.6612 0.9941 2071230 Maybridge1_003715 CCOC(=O)c1cnn(C)c1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A20 compound treatment 935303.0 356000.0 0.51 942893.0 343000.0 0.48 0.6959 0.9996 2071231 Maybridge1_003716 Clc1ccc(c2nn[nH]n2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A21 compound treatment 893262.0 314000.0 0.45 898297.0 298000.0 0.42 0.6097 0.9994 1669188 Maybridge1_003717 CC(C)(C)c1cc(N)c(s1)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A22 compound treatment 876907.0 298000.0 0.42 876088.0 276000.0 0.38 0.5713 0.9989 2071232 Maybridge1_003718 Cn1nccc1N2C(=O)CCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A23 mock treatment 824219.0 245000.0 0.35 847491.0 247000.0 0.34 0.4901 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 A24 mock treatment 152069.0 -427000.0 -0.61 153305.0 -447000.0 -0.62 -0.8704 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B01 compound treatment 851940.0 273000.0 0.39 813766.0 214000.0 0.3 0.4848 0.9915 2071233 Maybridge1_003719 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B02 compound treatment 857341.0 278000.0 0.4 831151.0 231000.0 0.32 0.5073 0.9948 2071234 Maybridge1_003720 Cn1ncc(C(=O)O/N=C/c2c(F)cccc2Cl)c1n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B03 compound treatment 907133.0 328000.0 0.47 902133.0 302000.0 0.42 0.6274 0.9987 2071235 Maybridge1_003721 FC(F)(F)c1ccc2Oc3ccsc3C(=O)Nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B04 compound treatment 886146.0 307000.0 0.44 869931.0 270000.0 0.38 0.5745 0.9973 1384033 Maybridge1_003722 CC(C)(C)c1ccc(CSc2nc(N)cc(O)n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B05 compound treatment 943456.0 364000.0 0.52 891851.0 292000.0 0.41 0.6538 0.9929 2071236 Maybridge1_003723 COC(=O)CSc1ncnc2sc3CCCCc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B06 compound treatment 895772.0 316000.0 0.45 851437.0 251000.0 0.35 0.566 0.9923 2071237 Maybridge1_003724 COCCOc1ccccc1NC(=S)NNC(=O)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B07 compound treatment 967875.0 389000.0 0.55 951385.0 351000.0 0.49 0.7371 0.9982 1091059 Maybridge1_003725 CCOC(=O)c1ccc(NC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B08 compound treatment 949634.0 370000.0 0.53 846577.0 246000.0 0.34 0.6154 0.9786 2071238 Maybridge1_003726 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4ccccc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B09 compound treatment 990611.0 411000.0 0.58 957630.0 357000.0 0.5 0.7661 0.9968 2071239 Maybridge1_003727 COc1cc(C(=O)NNS(=O)(=O)c2cc(C)c(Cl)c(C)c2)c(cc1OC)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B10 compound treatment 952726.0 373000.0 0.53 932405.0 332000.0 0.46 0.7031 0.9977 2071240 Maybridge1_003728 FC(F)(F)Oc1ccc(cc1)c2nnc(S)n2c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B11 compound treatment 958334.0 379000.0 0.54 951039.0 351000.0 0.49 0.7271 0.9988 2071241 Maybridge1_003729 C(c1nn[nH]n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B12 compound treatment 929040.0 350000.0 0.5 934209.0 334000.0 0.47 0.6811 0.9995 1919317 Maybridge1_003730 FC(F)(F)C1=Nc2ccccc2NC(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B13 compound treatment 980810.0 402000.0 0.57 985233.0 385000.0 0.54 0.7834 0.9995 1394339 Maybridge1_003731 Cc1cc(Br)ccc1S(=O)(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B14 compound treatment 943078.0 364000.0 0.52 960834.0 361000.0 0.5 0.7214 0.9999 2071242 Maybridge1_003732 Cc1onc(c1C(=O)NC(=S)N2CCOCC2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B15 compound treatment 946711.0 367000.0 0.52 958391.0 358000.0 0.5 0.7227 0.9997 1654305 Maybridge1_003733 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B16 compound treatment 938293.0 359000.0 0.51 906001.0 306000.0 0.43 0.6626 0.996 1322744 Maybridge1_003734 Cc1cccc(NC(=S)NC2CC3CC2C=C3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B17 compound treatment 971417.0 392000.0 0.56 986643.0 386000.0 0.54 0.7754 0.9999 2071243 Maybridge1_003735 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B18 compound treatment 893610.0 314000.0 0.45 894552.0 294000.0 0.41 0.6063 0.9991 1614026 Maybridge1_003736 COc1ccc(cc1OC)c2c(C)nc3ccc(Cl)cc3c2c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B19 compound treatment 934978.0 356000.0 0.51 973326.0 373000.0 0.52 0.7256 0.9999 1276489 Maybridge1_003737 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)CCC(=O)O)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B20 compound treatment 910572.0 331000.0 0.47 901595.0 301000.0 0.42 0.6303 0.9984 2071244 Maybridge1_003738 FC(F)(F)c1ccc(nc1)N2CCN(CC(=O)Nc3ccc4OCOc4c3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B21 compound treatment 931109.0 352000.0 0.5 919398.0 319000.0 0.45 0.6685 0.9983 1271205 Maybridge1_003739 COc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B22 compound treatment 879223.0 300000.0 0.43 902242.0 302000.0 0.42 0.5994 1.0 1738916 Maybridge1_003740 COC(=O)c1sccc1NC(=O)CC(C)(C)CC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B23 mock treatment 868830.0 290000.0 0.41 912275.0 312000.0 0.44 0.5989 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 B24 mock treatment 129228.0 -450000.0 -0.64 153284.0 -447000.0 -0.62 -0.8933 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C01 compound treatment 771485.0 192000.0 0.27 735783.0 136000.0 0.19 0.3269 0.9838 2071245 Maybridge1_003741 Cc1ccccc1NC(=S)NCc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C02 compound treatment 795097.0 216000.0 0.31 790787.0 191000.0 0.27 0.4049 0.9974 2071246 Maybridge1_003742 COC(=O)c1scc(C)c1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C03 compound treatment 828868.0 250000.0 0.35 813169.0 213000.0 0.3 0.461 0.9961 2071247 Maybridge1_003743 Cc1onc(c1C(=O)Oc2cc(nn2C)C(F)(F)F)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C04 compound treatment 876493.0 297000.0 0.42 844350.0 244000.0 0.34 0.5396 0.9943 2071248 Maybridge1_003744 C(c1nn[nH]n1)c2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C05 compound treatment 836102.0 257000.0 0.37 825178.0 225000.0 0.31 0.4801 0.9971 2071249 Maybridge1_003745 CCOC(=O)c1cnn(c1N)c2c([N+](=O)[O-])c(C)nn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C06 compound treatment 788585.0 209000.0 0.3 802025.0 202000.0 0.28 0.4095 0.9996 2071250 Maybridge1_003746 Cn1ncc2c(=O)[nH]cnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C07 compound treatment 873473.0 294000.0 0.42 792441.0 192000.0 0.27 0.4854 0.9769 1505403 Maybridge1_003747 O=C1CCc2ccccc2N1Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C08 compound treatment 841692.0 262000.0 0.37 836508.0 236000.0 0.33 0.4969 0.9981 1586389 Maybridge1_003748 CCCc1nc(N)ncc1C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C09 compound treatment 897872.0 319000.0 0.45 844623.0 244000.0 0.34 0.5614 0.9902 1045287 Maybridge1_003749 COC(=O)C1CCC(CC1)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C10 compound treatment 858501.0 279000.0 0.4 799210.0 199000.0 0.28 0.477 0.9847 2071251 Maybridge1_003750 NNC(=O)c1cnn(c1C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C11 compound treatment 1130081.0 551000.0 0.78 1013699.0 413000.0 0.58 0.9616 0.9887 2071252 Maybridge1_003751 COC(=O)C(C#N)C1C(=C(N)Oc2c(Br)cc(Br)cc12)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C12 compound treatment 854141.0 275000.0 0.39 807896.0 208000.0 0.29 0.4812 0.9891 2071253 Maybridge1_003752 COC(=O)c1sccc1Oc2ccc(cc2NS(=O)(=O)c3ccc(F)cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C13 compound treatment 885293.0 306000.0 0.44 766512.0 166000.0 0.23 0.4717 0.9566 2071254 Maybridge1_003753 Cc1ccc(OCC2SCCN2C(=O)c3ccc(F)cc3)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C14 compound treatment 859524.0 280000.0 0.4 781778.0 182000.0 0.25 0.4608 0.976 2071255 Maybridge1_003754 CCOc1ccsc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C15 compound treatment 897973.0 319000.0 0.45 785467.0 185000.0 0.26 0.5031 0.9645 2071256 Maybridge1_003755 CCOC(=O)c1c(C)csc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C16 compound treatment 850792.0 271000.0 0.39 800616.0 200000.0 0.28 0.4706 0.9874 2071257 Maybridge1_003756 Cc1csc2c(S)ncnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C17 compound treatment 888437.0 309000.0 0.44 877338.0 277000.0 0.39 0.5842 0.9979 2071258 Maybridge1_003757 Nc1c(C#N)cnc2c(Br)cnn12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C18 compound treatment 827291.0 248000.0 0.35 807073.0 207000.0 0.29 0.4534 0.995 1400072 Maybridge1_003758 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccc(F)cc2F)S(=O)(=O)c3ccc(NC(=O)C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C19 compound treatment 867376.0 288000.0 0.41 808986.0 209000.0 0.29 0.4956 0.986 1647208 Maybridge1_003759 CCOC(=O)c1c(C)csc1NC(=O)Nc2c(C)onc2c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C20 compound treatment 849684.0 270000.0 0.38 811618.0 211000.0 0.29 0.4804 0.9914 2071259 Maybridge1_003760 Clc1ccc(cc1Cl)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C21 compound treatment 833116.0 254000.0 0.36 805202.0 205000.0 0.29 0.4574 0.9933 2071260 Maybridge1_003761 CC(=O)c1sc(cc1N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C22 compound treatment 822346.0 243000.0 0.35 730794.0 131000.0 0.18 0.3732 0.9552 2071261 Maybridge1_003762 CCOC(=O)c1ccsc1NC(=O)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C23 mock treatment 839650.0 260000.0 0.37 805323.0 205000.0 0.29 0.4641 0.9919 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 C24 mock treatment 153452.0 -426000.0 -0.61 155464.0 -445000.0 -0.62 -0.8668 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D01 compound treatment 867992.0 289000.0 0.41 832871.0 233000.0 0.32 0.5197 0.9932 1343139 Maybridge1_003763 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(F)c(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D02 compound treatment 881688.0 302000.0 0.43 807086.0 207000.0 0.29 0.5081 0.9812 1490566 Maybridge1_003764 Cc1onc(c1C(=O)Nc2ccccc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D03 compound treatment 955092.0 376000.0 0.53 928379.0 328000.0 0.46 0.7015 0.997 1387616 Maybridge1_003765 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cccc(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D04 compound treatment 952820.0 374000.0 0.53 926215.0 326000.0 0.45 0.6971 0.997 2071262 Maybridge1_003766 Oc1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D05 compound treatment 966748.0 387000.0 0.55 880088.0 280000.0 0.39 0.6656 0.9857 1544193 Maybridge1_003767 COc1cc2ncnc(Sc3ccc(C)cc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D06 compound treatment 916598.0 337000.0 0.48 892378.0 292000.0 0.41 0.6273 0.9967 2071263 Maybridge1_003768 COC(=O)c1ccccc1NC(=S)NNC(=O)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D07 compound treatment 982297.0 403000.0 0.57 977118.0 377000.0 0.53 0.7769 0.9991 2071264 Maybridge1_003769 Cn1nccc1NC(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D08 compound treatment 949477.0 370000.0 0.53 943723.0 343000.0 0.48 0.711 0.9989 2071265 Maybridge1_003770 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4cc(Cl)cc(Cl)c4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D09 compound treatment 989808.0 411000.0 0.58 1002177.0 402000.0 0.56 0.8092 0.9998 2071266 Maybridge1_003771 Cc1ccc(C)n1c2sc3CCCCc3c2C(=O)NNC(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D10 compound treatment 936846.0 358000.0 0.51 958172.0 358000.0 0.5 0.7126 1.0 2071267 Maybridge1_003772 FC(F)(F)c1ccc(OCC#N)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D11 compound treatment 1013869.0 435000.0 0.62 931138.0 331000.0 0.46 0.7633 0.9897 1194918 Maybridge1_003773 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D12 compound treatment 932748.0 353000.0 0.5 905500.0 305000.0 0.43 0.6565 0.9966 2071268 Maybridge1_003774 CCOC(=O)c1c(N)scc1c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D13 compound treatment 977731.0 398000.0 0.57 969049.0 369000.0 0.51 0.7644 0.9988 1589664 Maybridge1_003775 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)on3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D14 compound treatment 937892.0 359000.0 0.51 913864.0 314000.0 0.44 0.6699 0.9971 1122688 Maybridge1_003776 CC1CCCC(C)N1C(=S)NC(=O)c2c(C)onc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D15 compound treatment 1000371.0 421000.0 0.6 1030323.0 430000.0 0.6 0.8476 1.0 2071269 Maybridge1_003777 Clc1ccc(CSc2ncnc3sc4CCCCc4c23)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D16 compound treatment 975568.0 396000.0 0.56 1000247.0 400000.0 0.56 0.793 1.0 2071270 Maybridge1_003778 S=C(NC1CC2CC1C=C2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D17 compound treatment 1002489.0 423000.0 0.6 1000485.0 400000.0 0.56 0.8203 0.9993 1545146 Maybridge1_003779 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccc4ccccc4c3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D18 compound treatment 949607.0 370000.0 0.53 964498.0 364000.0 0.51 0.7316 0.9998 1144861 Maybridge1_003780 CCN(CC)c1ccc(NC(=S)Nc2ccc(OC)cc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D19 compound treatment 988127.0 409000.0 0.58 987884.0 388000.0 0.54 0.7934 0.9993 1466175 Maybridge1_003781 COc1cc(NC(=O)c2ccccc2)c(cc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D20 compound treatment 955631.0 376000.0 0.54 969067.0 369000.0 0.51 0.7422 0.9998 1146514 Maybridge1_003782 Cc1cc(N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)c4ccccc4n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D21 compound treatment 987228.0 408000.0 0.58 972170.0 372000.0 0.52 0.777 0.9984 2071271 Maybridge1_003783 COc1cc2ncnc(Nc3ccc(OC(F)(F)F)cc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D22 compound treatment 917345.0 338000.0 0.48 950710.0 350000.0 0.49 0.6856 1.0 2071272 Maybridge1_003784 C1Oc2ccc(/N=C/3\SCC4CCCCN43)cc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D23 mock treatment 927746.0 348000.0 0.5 963152.0 363000.0 0.51 0.7083 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 D24 mock treatment 153525.0 -426000.0 -0.61 76495.0 -524000.0 -0.73 -0.9446 -0.9957 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E01 compound treatment 903999.0 325000.0 0.46 852339.0 252000.0 0.35 0.5751 0.991 1546515 Maybridge1_003785 Cc1ccc(NC(=S)N(CCC#N)CCc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E02 compound treatment 1412456.0 833000.0 1.18 1381203.0 781000.0 1.09 1.608 0.9991 1704263 Maybridge1_003786 CCOC(=O)CC(=O)Nc1c(C)csc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E03 compound treatment 972974.0 394000.0 0.56 987864.0 388000.0 0.54 0.7782 0.9998 1427173 Maybridge1_003787 COc1ccc(Cc2n[nH]c(=O)o2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E04 compound treatment 968843.0 390000.0 0.55 978534.0 378000.0 0.53 0.7648 0.9997 2071273 Maybridge1_003788 OC(=O)c1cnn(c1C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E05 compound treatment 1011681.0 432000.0 0.61 982977.0 383000.0 0.53 0.8123 0.9975 2071274 Maybridge1_003789 Cc1nn(C)c(c1[N+](=O)[O-])n2ncc(C#N)c2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E06 compound treatment 941304.0 362000.0 0.51 924867.0 325000.0 0.45 0.6842 0.998 2071275 Maybridge1_003790 COC(=O)CSc1ncnc2c(C)csc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E07 compound treatment 966826.0 388000.0 0.55 1001636.0 401000.0 0.56 0.7856 1.0 2071276 Maybridge1_003791 CCOC(=O)C1=C(C)N=C2SCCC(=O)N2C1c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E08 compound treatment 973257.0 394000.0 0.56 975135.0 375000.0 0.52 0.7659 0.9994 1257517 Maybridge1_003792 Clc1ccc(NC(=O)C2CCc3ccccc3O2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E09 compound treatment 1004168.0 425000.0 0.6 990783.0 391000.0 0.54 0.8124 0.9987 1196450 Maybridge1_003793 COc1ccc2-c3nc(N)sc3CCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E10 compound treatment 919565.0 340000.0 0.48 958828.0 359000.0 0.5 0.6958 0.9999 2071277 Maybridge1_003794 COC(=O)c1sccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E11 compound treatment 1168750.0 589000.0 0.84 1169445.0 569000.0 0.79 1.1541 0.9996 2071278 Maybridge1_003795 COc1ccc(/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E12 compound treatment 1001876.0 423000.0 0.6 985817.0 386000.0 0.54 0.8052 0.9985 2071279 Maybridge1_003796 COC(=O)c1scc(C)c1N2C(=O)C=CC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E13 compound treatment 1010166.0 431000.0 0.61 1010917.0 411000.0 0.57 0.8383 0.9994 2071280 Maybridge1_003797 OC(=O)c1ccccc1SCC(=O)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E14 compound treatment 933567.0 354000.0 0.5 968144.0 368000.0 0.51 0.7191 1.0 2071281 Maybridge1_003798 CCOc1ccsc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E15 compound treatment 1000020.0 421000.0 0.6 1034661.0 434000.0 0.61 0.8515 1.0 2071282 Maybridge1_003799 CC(=O)CSc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E16 compound treatment 944093.0 365000.0 0.52 982407.0 382000.0 0.53 0.7437 0.9999 2071283 Maybridge1_003800 CCOC(=O)c1cc2c(nn(C)c2s1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E17 compound treatment 1048480.0 469000.0 0.67 1125117.0 525000.0 0.73 0.9894 0.9989 1108872 Maybridge1_003801 N#CCc1nc2ccccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E18 compound treatment 946006.0 367000.0 0.52 1018015.0 418000.0 0.58 0.7808 0.9985 2071284 Maybridge1_003802 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccccc2C(F)(F)F)S(=O)(=O)c3ccc(NC(=O)C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E19 compound treatment 983167.0 404000.0 0.57 1015928.0 416000.0 0.58 0.8161 1.0 2071285 Maybridge1_003803 CCOC(=O)c1c(C)csc1NC(=O)Nc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E20 compound treatment 995564.0 416000.0 0.59 1041581.0 441000.0 0.62 0.8539 0.9998 2071286 Maybridge1_003804 Clc1cccc(Cl)c1c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E21 compound treatment 977820.0 399000.0 0.57 977613.0 377000.0 0.53 0.7729 0.9993 1360504 Maybridge1_003805 CC(C)(C)c1cc(NC(=O)CC#N)c(s1)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E22 compound treatment 962509.0 383000.0 0.54 959543.0 359000.0 0.5 0.7397 0.9991 1513979 Maybridge1_003806 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E23 mock treatment 932820.0 354000.0 0.5 943843.0 344000.0 0.48 0.6944 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 E24 mock treatment 154227.0 -425000.0 -0.6 153117.0 -447000.0 -0.62 -0.8684 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F01 compound treatment 924610.0 345000.0 0.49 846036.0 246000.0 0.34 0.5897 0.9846 1584709 Maybridge1_003807 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F02 compound treatment 922552.0 343000.0 0.49 893849.0 294000.0 0.41 0.6347 0.9962 2071287 Maybridge1_003808 CCOC(=O)C(=CNNC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F03 compound treatment 985404.0 406000.0 0.58 911870.0 312000.0 0.43 0.7157 0.9902 1486847 Maybridge1_003809 O=c1[nH]cnc2sc3CCCCc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F04 compound treatment 985706.0 406000.0 0.58 973564.0 373000.0 0.52 0.7769 0.9986 1945423 Maybridge1_003810 Nc1cc(O)nc(SCc2ccc(Cl)cc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F05 compound treatment 995658.0 416000.0 0.59 973818.0 374000.0 0.52 0.7871 0.998 2071288 Maybridge1_003811 COc1ncnc2sc3CCCCc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F06 compound treatment 987440.0 408000.0 0.58 916292.0 316000.0 0.44 0.7221 0.9908 2071289 Maybridge1_003812 Cc1csc(N)c1c2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F07 compound treatment 999543.0 420000.0 0.6 997374.0 397000.0 0.55 0.8143 0.9993 2071290 Maybridge1_003813 Cn1nccc1NC(=O)Nc2cccc(Br)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F08 compound treatment 986130.0 407000.0 0.58 950373.0 350000.0 0.49 0.7544 0.9964 2071291 Maybridge1_003814 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)Nc4ccc(F)cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F09 compound treatment 992158.0 413000.0 0.59 1021809.0 422000.0 0.59 0.8309 1.0 1728277 Maybridge1_003815 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F10 compound treatment 990570.0 411000.0 0.58 960240.0 360000.0 0.5 0.7686 0.9971 2071292 Maybridge1_003816 Nc1ccccc1Sc2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F11 compound treatment 980521.0 401000.0 0.57 975765.0 376000.0 0.52 0.7738 0.9991 1590495 Maybridge1_003817 Cc1cc(c(C)cc1Cl)S(=O)(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F12 compound treatment 953573.0 374000.0 0.53 938284.0 338000.0 0.47 0.7098 0.9982 2071293 Maybridge1_003818 O=c1[nH]cnc2scc(c3ccccc3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F13 compound treatment 918847.0 340000.0 0.48 1011967.0 412000.0 0.57 0.7475 0.9963 1333321 Maybridge1_003819 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3cccc(Cl)c3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F14 compound treatment 966237.0 387000.0 0.55 1023020.0 423000.0 0.59 0.8061 0.9994 1199492 Maybridge1_003820 CC1CCN(CC1)C(=S)NC2CC3CCC2C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F15 compound treatment 974132.0 395000.0 0.56 1041762.0 442000.0 0.62 0.8325 0.9989 1180444 Maybridge1_003821 COc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)on3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F16 compound treatment 916596.0 337000.0 0.48 961829.0 362000.0 0.5 0.6958 0.9997 1218416 Maybridge1_003822 CCOc1ccc(NC(=S)NC2CC3CC2C=C3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F17 compound treatment 1016890.0 438000.0 0.62 1009418.0 409000.0 0.57 0.8436 0.9991 1356531 Maybridge1_003823 COc1cc(NC(=O)c2ccc(Cl)cc2)c(cc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F18 compound treatment 1121862.0 543000.0 0.77 1144181.0 544000.0 0.76 1.082 1.0 1299812 Maybridge1_003824 NC(=O)c1c(N)sc2CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F19 compound treatment 1001865.0 423000.0 0.6 1010430.0 410000.0 0.57 0.8295 0.9997 1679441 Maybridge1_003825 COc1cc(NC(=O)c2cccs2)c(cc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F20 compound treatment 988835.0 410000.0 0.58 1001522.0 401000.0 0.56 0.8076 0.9998 1704487 Maybridge1_003826 Cc1cc(N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3)c4ccccc4n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F21 compound treatment 1017307.0 438000.0 0.62 1055286.0 455000.0 0.63 0.8892 1.0 2071294 Maybridge1_003827 CC(=O)c1sc(cc1NC(=O)c2ccc(Cl)cc2)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F22 compound treatment 964074.0 385000.0 0.55 980203.0 380000.0 0.53 0.7617 0.9999 2071295 Maybridge1_003828 Cc1scc(NS(=O)(=O)c2ccc(C)cc2)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F23 mock treatment 963661.0 384000.0 0.55 995646.0 395000.0 0.55 0.7765 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 F24 mock treatment 142692.0 -437000.0 -0.62 152467.0 -448000.0 -0.62 -0.8806 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G01 compound treatment 841120.0 262000.0 0.37 826894.0 227000.0 0.32 0.4868 0.9967 2071296 Maybridge1_003829 FC(F)(F)c1cccc(NC(=S)N(CCC#N)CCc2ccccn2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G02 compound treatment 865440.0 286000.0 0.41 866193.0 266000.0 0.37 0.55 0.9989 2071297 Maybridge1_003830 COC(=O)c1sccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G03 compound treatment 954885.0 376000.0 0.53 928299.0 328000.0 0.46 0.7012 0.997 2071298 Maybridge1_003831 CSc1cc(n[nH]1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G04 compound treatment 924363.0 345000.0 0.49 937311.0 337000.0 0.47 0.6794 0.9998 2071299 Maybridge1_003832 CCCc1c(cnn1c2ccccc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G05 compound treatment 943944.0 365000.0 0.52 926233.0 326000.0 0.45 0.6882 0.9979 1059689 Maybridge1_003833 CCOC(=O)c1cnn(C)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G06 compound treatment 914877.0 336000.0 0.48 977910.0 378000.0 0.53 0.7099 0.9988 2071300 Maybridge1_003834 Cc1csc2c(SCC(=O)NN)ncnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G07 compound treatment 985636.0 406000.0 0.58 973877.0 374000.0 0.52 0.7771 0.9987 1006328 Maybridge1_003835 OC(=O)C1CCC(CC1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G08 compound treatment 944211.0 365000.0 0.52 951853.0 352000.0 0.49 0.7137 0.9996 2071301 Maybridge1_003836 N/C(=N/OC(=O)C1CCc2ccccc2O1)/c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G09 compound treatment 943189.0 364000.0 0.52 998975.0 399000.0 0.56 0.7592 0.9994 1162404 Maybridge1_003837 Nc1nc-2c(CCc3ccccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G10 compound treatment 907798.0 329000.0 0.47 947036.0 347000.0 0.48 0.6724 0.9998 2071302 Maybridge1_003838 NNC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G11 compound treatment 937619.0 358000.0 0.51 938915.0 339000.0 0.47 0.6943 0.9993 2071303 Maybridge1_003839 Clc1ccc(cc1)C(=O)ON=C2C3CC4CC(C3)CC2C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G12 compound treatment 925107.0 346000.0 0.49 981229.0 381000.0 0.53 0.7235 0.9993 2071304 Maybridge1_003840 COC(=O)c1scc(N)c1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G13 compound treatment 955120.0 376000.0 0.53 982527.0 382000.0 0.53 0.7549 1.0 2071305 Maybridge1_003841 CCOC(=O)c1csc(N/N=C/2\CCCc3cc(OC)ccc23)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G14 compound treatment 915936.0 337000.0 0.48 1012647.0 412000.0 0.58 0.7452 0.9958 1415299 Maybridge1_003842 CCOc1ccsc1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G15 compound treatment 987248.0 408000.0 0.58 1037340.0 437000.0 0.61 0.8413 0.9997 1245805 Maybridge1_003843 COC(=O)c1ccccc1NC(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G16 compound treatment 947528.0 368000.0 0.52 984882.0 385000.0 0.54 0.7496 0.9999 1626184 Maybridge1_003844 COC(=O)C1=C(N)CCS1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G17 compound treatment 951103.0 372000.0 0.53 1043699.0 443000.0 0.62 0.8112 0.997 2071306 Maybridge1_003845 O=c1nc[nH]c2ccsc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G18 compound treatment 928575.0 349000.0 0.5 988664.0 388000.0 0.54 0.7343 0.9991 2071307 Maybridge1_003846 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(NC(=O)C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G19 compound treatment 947557.0 368000.0 0.52 1026971.0 427000.0 0.6 0.7912 0.998 1512183 Maybridge1_003847 CCOC(=O)CC(=O)Nc1scc(C)c1C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G20 compound treatment 900979.0 322000.0 0.46 962479.0 362000.0 0.51 0.6807 0.9988 2071308 Maybridge1_003848 CC(C)(C)c1ccc(cc1)c2nnnn2Cc3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G21 compound treatment 931127.0 352000.0 0.5 930302.0 330000.0 0.46 0.6793 0.9991 1630143 Maybridge1_003849 CCOC(=O)c1cnn(C)c1NC(=O)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G22 compound treatment 894404.0 315000.0 0.45 885634.0 285000.0 0.4 0.5983 0.9983 2071309 Maybridge1_003850 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G23 mock treatment 913544.0 334000.0 0.48 964546.0 364000.0 0.51 0.6954 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 G24 mock treatment 145269.0 -434000.0 -0.62 170216.0 -430000.0 -0.6 -0.8605 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H01 compound treatment 899502.0 320000.0 0.46 818470.0 218000.0 0.3 0.5372 0.9808 1247158 Maybridge1_003851 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H02 compound treatment 859471.0 280000.0 0.4 844977.0 245000.0 0.34 0.5231 0.997 2071310 Maybridge1_003852 Cc1ccc(cc1)c2nnc(o2)c3cnn(c3C(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H03 compound treatment 921874.0 343000.0 0.49 929872.0 330000.0 0.46 0.6696 0.9996 1273506 Maybridge1_003853 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H04 compound treatment 963747.0 384000.0 0.55 941936.0 342000.0 0.48 0.7236 0.9977 1004482 Maybridge1_003854 CC(=O)CC(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H05 compound treatment 1012751.0 433000.0 0.62 933585.0 333000.0 0.46 0.7646 0.9903 2071311 Maybridge1_003855 COc1cc2ncnc(Sc3ccc(Cl)cc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H06 compound treatment 921548.0 342000.0 0.49 923718.0 323000.0 0.45 0.6632 0.9993 2071312 Maybridge1_003856 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)S(=O)(=O)c4ccc(C)cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H07 compound treatment 1039788.0 460000.0 0.65 972512.0 372000.0 0.52 0.8302 0.9934 2071313 Maybridge1_003857 Cn1nccc1NC(=S)Nc2ccc(Br)cc2OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H08 compound treatment 908560.0 329000.0 0.47 943713.0 343000.0 0.48 0.6698 0.9999 2071314 Maybridge1_003858 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=S)Nc4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H09 compound treatment 973895.0 395000.0 0.56 971436.0 371000.0 0.52 0.7629 0.9992 1333925 Maybridge1_003859 COc1cccc(OC)c1C(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H10 compound treatment 971729.0 392000.0 0.56 928916.0 329000.0 0.46 0.7188 0.9952 2071315 Maybridge1_003860 N/C(=N/O)/Cn1ccc(n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H11 compound treatment 970772.0 391000.0 0.56 960631.0 360000.0 0.5 0.7491 0.9987 2071316 Maybridge1_003861 Cn1nccc1NC(=O)CCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H12 compound treatment 904050.0 325000.0 0.46 947445.0 347000.0 0.48 0.669 0.9997 2071317 Maybridge1_003862 CC1(C)COCCN1C(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H13 compound treatment 953291.0 374000.0 0.53 970430.0 370000.0 0.52 0.7412 0.9999 1484331 Maybridge1_003863 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(C#N)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H14 compound treatment 935965.0 357000.0 0.51 968378.0 368000.0 0.51 0.7217 1.0 1510294 Maybridge1_003864 CCC(CO)NC(=S)NC1CC2CCC1C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H15 compound treatment 951123.0 372000.0 0.53 970988.0 371000.0 0.52 0.7395 0.9999 1985554 Maybridge1_003865 CCSc1ncnc2sc3CCCCc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H16 compound treatment 986452.0 407000.0 0.58 938448.0 338000.0 0.47 0.743 0.9948 1390457 Maybridge1_003866 CCOc1ccccc1NC(=S)NC2CC3CCC2C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H17 compound treatment 995390.0 416000.0 0.59 1005716.0 405000.0 0.57 0.8183 0.9997 2071318 Maybridge1_003867 COc1cc(NC(=O)c2ccc(OC(F)(F)F)cc2)c(cc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H18 compound treatment 910168.0 331000.0 0.47 939107.0 339000.0 0.47 0.6669 1.0 1566872 Maybridge1_003868 COc1cccc(NC(=S)Nc2ccccc2n3cccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H19 compound treatment 969380.0 390000.0 0.55 994316.0 394000.0 0.55 0.7809 1.0 2071319 Maybridge1_003869 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CN2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H20 compound treatment 936065.0 357000.0 0.51 891307.0 291000.0 0.41 0.6458 0.9939 1337960 Maybridge1_003870 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H21 compound treatment 940186.0 361000.0 0.51 956454.0 356000.0 0.5 0.7142 0.9999 1393179 Maybridge1_003871 CC(=O)Nc1cc(sc1C(=O)N)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H22 compound treatment 928361.0 349000.0 0.5 943715.0 343000.0 0.48 0.6898 0.9998 1363593 Maybridge1_003872 Cc1cc(Cl)ccc1Nc2nnns2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H23 mock treatment 945376.0 366000.0 0.52 968154.0 368000.0 0.51 0.731 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 H24 mock treatment 157632.0 -422000.0 -0.6 171892.0 -428000.0 -0.6 -0.8464 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I01 compound treatment 852926.0 274000.0 0.39 843825.0 244000.0 0.34 0.5154 0.9977 2071320 Maybridge1_003873 CN(C)CCCNc1c([N+](=O)[O-])c(C)nn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I02 compound treatment 933116.0 354000.0 0.5 887776.0 288000.0 0.4 0.6394 0.9937 2071321 Maybridge1_003874 COC(=O)c1scc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I03 compound treatment 952050.0 373000.0 0.53 959867.0 360000.0 0.5 0.7295 0.9996 2071322 Maybridge1_003875 CCOc1cc(nc(S)n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I04 compound treatment 946424.0 367000.0 0.52 952446.0 352000.0 0.49 0.7165 0.9995 2071323 Maybridge1_003876 CCCc1c(cnn1c2ccc(Cl)cc2)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I05 compound treatment 983669.0 404000.0 0.58 981179.0 381000.0 0.53 0.7823 0.9992 2071324 Maybridge1_003877 O=C1/C(=C/c2cccs2)/Cc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I06 compound treatment 963604.0 384000.0 0.55 960345.0 360000.0 0.5 0.7416 0.9991 2071325 Maybridge1_003878 Cc1csc2ncnc(Sc3ccccc3N)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I07 compound treatment 1000049.0 421000.0 0.6 1018360.0 418000.0 0.58 0.8355 0.9999 2071326 Maybridge1_003879 CCOC(=O)CCSC1=NC(C(=C(C)N1)C(=O)OCC)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I08 compound treatment 1008458.0 429000.0 0.61 1035151.0 435000.0 0.61 0.8605 1.0 2071327 Maybridge1_003880 COC(=O)c1cscc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I09 compound treatment 968212.0 389000.0 0.55 891629.0 291000.0 0.41 0.6785 0.9885 1035457 Maybridge1_003881 CC(C)CC1NC(=O)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I10 compound treatment 937020.0 358000.0 0.51 968563.0 368000.0 0.51 0.723 1.0 2071328 Maybridge1_003882 COC(=O)c1sccc1Oc2ccc(Cl)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I11 compound treatment 915111.0 336000.0 0.48 938368.0 338000.0 0.47 0.6712 1.0 2071329 Maybridge1_003883 Fc1ccc(cc1)C(=O)ON=C2C3CC4CC(C3)CC2C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I12 compound treatment 910417.0 331000.0 0.47 990753.0 391000.0 0.54 0.7181 0.9974 1732993 Maybridge1_003884 COC(=O)c1c(C)scc1NC(=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I13 compound treatment 963537.0 384000.0 0.55 975617.0 375000.0 0.52 0.7566 0.9998 2071330 Maybridge1_003885 COC(=O)CN(C(=O)c1ccccc1[N+](=O)[O-])C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I14 compound treatment 934878.0 356000.0 0.51 972052.0 372000.0 0.52 0.7243 0.9999 2071331 Maybridge1_003886 COC(=O)c1sccc1n2c(C)ccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I15 compound treatment 996828.0 418000.0 0.59 992076.0 392000.0 0.55 0.8063 0.9991 2071332 Maybridge1_003887 CC(=O)CSC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I16 compound treatment 916962.0 338000.0 0.48 953074.0 353000.0 0.49 0.6875 0.9999 2071333 Maybridge1_003888 COC(=O)C(Cc1ccc(F)cc1)(Cc2ccc(F)cc2)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I17 compound treatment 1035405.0 456000.0 0.65 1070128.0 470000.0 0.66 0.9221 1.0 2071334 Maybridge1_003889 O/C=C(\C#N)/c1nc2ccccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I18 compound treatment 918341.0 339000.0 0.48 972856.0 373000.0 0.52 0.7084 0.9993 1618849 Maybridge1_003890 OCCNc1ncnc2sccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I19 compound treatment 945672.0 366000.0 0.52 961521.0 361000.0 0.5 0.7247 0.9999 2071335 Maybridge1_003891 COC(=O)c1sc(cc1N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I20 compound treatment 914704.0 335000.0 0.48 1007415.0 407000.0 0.57 0.7388 0.9962 2071336 Maybridge1_003892 CC(=O)c1sc(cc1N)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I21 compound treatment 951421.0 372000.0 0.53 976525.0 376000.0 0.52 0.7453 1.0 2071337 Maybridge1_003893 COC(=O)c1sc(cc1N)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I22 compound treatment 933531.0 354000.0 0.5 942120.0 342000.0 0.48 0.6934 0.9996 2071338 Maybridge1_003894 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I23 mock treatment 944766.0 365000.0 0.52 992249.0 392000.0 0.55 0.7541 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 I24 mock treatment 155579.0 -424000.0 -0.6 168843.0 -431000.0 -0.6 -0.8515 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J01 compound treatment 861797.0 283000.0 0.4 823179.0 223000.0 0.31 0.504 0.992 2071339 Maybridge1_003895 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J02 compound treatment 943243.0 364000.0 0.52 836089.0 236000.0 0.33 0.5986 0.9761 1724940 Maybridge1_003896 CC(C)(C)c1cc2ncnc(N3CCN(CC3)c4ncnc5cc(sc45)C(C)(C)C)c2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J03 compound treatment 968571.0 389000.0 0.55 904186.0 304000.0 0.42 0.6912 0.9913 2071340 Maybridge1_003897 CCOC(=O)c1c(sc2CCCCc12)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J04 compound treatment 929156.0 350000.0 0.5 933901.0 334000.0 0.47 0.6809 0.9994 2071341 Maybridge1_003898 NC(=N)NC(=N)NCc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J05 compound treatment 1005873.0 427000.0 0.61 875961.0 276000.0 0.38 0.7009 0.9758 2071342 Maybridge1_003899 CCNC(=S)Nc1c(C)cc(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J06 compound treatment 936719.0 357000.0 0.51 947157.0 347000.0 0.48 0.7016 0.9997 2071343 Maybridge1_003900 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)S(=O)(=O)c4ccc(Cl)cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J07 compound treatment 1030621.0 451000.0 0.64 953244.0 353000.0 0.49 0.802 0.9914 2071344 Maybridge1_003901 Cn1nccc1NC(=O)Nc2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J08 compound treatment 893286.0 314000.0 0.45 934145.0 334000.0 0.47 0.6451 0.9998 2071345 Maybridge1_003902 Clc1ccc(Sc2ncnc3ccsc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J09 compound treatment 1008933.0 430000.0 0.61 985083.0 385000.0 0.54 0.8116 0.9979 1286388 Maybridge1_003903 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J10 compound treatment 957707.0 378000.0 0.54 924955.0 325000.0 0.45 0.7008 0.9963 2071346 Maybridge1_003904 FC(F)(F)c1ccn(n1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J11 compound treatment 987927.0 409000.0 0.58 930958.0 331000.0 0.46 0.7371 0.9935 1327348 Maybridge1_003905 Cn1nccc1NS(=O)(=O)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J12 compound treatment 932521.0 353000.0 0.5 941029.0 341000.0 0.48 0.6913 0.9996 2071347 Maybridge1_003906 CN(C)/N=C(/C(=O)C(F)(F)F)\c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J13 compound treatment 1004339.0 425000.0 0.6 997487.0 397000.0 0.55 0.8192 0.9991 1205526 Maybridge1_003907 Cn1nccc1NS(=O)(=O)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J14 compound treatment 968163.0 389000.0 0.55 941753.0 342000.0 0.48 0.7278 0.9972 2071348 Maybridge1_003908 [O-][N+](=O)c1cccc(c1)C(=O)NC(=S)Nc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J15 compound treatment 998830.0 420000.0 0.6 930285.0 330000.0 0.46 0.7474 0.9918 2071349 Maybridge1_003909 CC(=O)c1sc(cc1N)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J16 compound treatment 938193.0 359000.0 0.51 952267.0 352000.0 0.49 0.7081 0.9998 2071350 Maybridge1_003910 OCCNNC(=S)NC1CC2CC1C=C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J17 compound treatment 973081.0 394000.0 0.56 986502.0 386000.0 0.54 0.7769 0.9998 1513059 Maybridge1_003911 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J18 compound treatment 924097.0 345000.0 0.49 917059.0 317000.0 0.44 0.6592 0.9987 2071351 Maybridge1_003912 CNc1nc(cs1)c2ccc(Cl)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J19 compound treatment 974861.0 396000.0 0.56 943086.0 343000.0 0.48 0.7359 0.9967 1212957 Maybridge1_003913 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J20 compound treatment 938658.0 359000.0 0.51 891439.0 291000.0 0.41 0.6486 0.9935 1715187 Maybridge1_003914 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)N3CCN(C)CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J21 compound treatment 959762.0 380000.0 0.54 980950.0 381000.0 0.53 0.7581 1.0 2071352 Maybridge1_003915 Cn1ncc2c(N/N=C/c3ccc(Cl)cc3)ncnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J22 compound treatment 918149.0 339000.0 0.48 942948.0 343000.0 0.48 0.6787 1.0 1397071 Maybridge1_003916 OC(=O)COCC(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J23 mock treatment 919932.0 341000.0 0.48 976505.0 376000.0 0.52 0.7136 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 J24 mock treatment 129563.0 -450000.0 -0.64 163007.0 -437000.0 -0.61 -0.8834 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K01 compound treatment 860458.0 281000.0 0.4 808635.0 208000.0 0.29 0.4883 0.9877 2071353 Maybridge1_003917 CSC(=NC(=O)c1c(Cl)cccc1Cl)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K02 compound treatment 885140.0 306000.0 0.43 870544.0 270000.0 0.38 0.5741 0.9975 2071354 Maybridge1_003918 Cc1csc(C(=O)O)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K03 compound treatment 946655.0 367000.0 0.52 941716.0 341000.0 0.48 0.7062 0.9989 2071355 Maybridge1_003919 COc1ccc(NCCC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K04 compound treatment 892320.0 313000.0 0.45 920959.0 321000.0 0.45 0.6311 1.0 2071356 Maybridge1_003920 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K05 compound treatment 935648.0 356000.0 0.51 903771.0 304000.0 0.42 0.6577 0.996 2071357 Maybridge1_003921 COc1nc-2c(Cc3ccccc32)c(c4cccs4)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K06 compound treatment 928183.0 349000.0 0.5 892296.0 292000.0 0.41 0.6389 0.9952 2071358 Maybridge1_003922 Nc1cc(nc(N)n1)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K07 compound treatment 940029.0 361000.0 0.51 953479.0 353000.0 0.49 0.7111 0.9998 1317778 Maybridge1_003923 CCOC(=O)C1=C(C)NC(=S)N(C1c2cccs2)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K08 compound treatment 932629.0 353000.0 0.5 936484.0 336000.0 0.47 0.6869 0.9994 2071327 Maybridge1_003924 COC(=O)c1cscc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K09 compound treatment 1205039.0 626000.0 0.89 1226265.0 626000.0 0.87 1.2466 1.0 2071359 Maybridge1_003925 N#C/C(=C\c1cccs1)/c2nc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K10 compound treatment 915389.0 336000.0 0.48 912163.0 312000.0 0.44 0.6456 0.9989 2071360 Maybridge1_003926 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K11 compound treatment 889969.0 311000.0 0.44 908269.0 308000.0 0.43 0.6162 0.9999 2071361 Maybridge1_003927 FC(F)(F)c1cccc(c1)C(=O)ON=C2C3CC4CC(C3)CC2C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K12 compound treatment 901898.0 323000.0 0.46 912362.0 312000.0 0.44 0.6322 0.9997 2071362 Maybridge1_003928 CCOC(=O)c1cnn(c1C(F)(F)F)c2ccc(N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K13 compound treatment 942203.0 363000.0 0.52 911543.0 311000.0 0.43 0.672 0.9963 2071363 Maybridge1_003929 CCOC(=O)CN(C(=O)c1ccccc1[N+](=O)[O-])C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K14 compound treatment 890510.0 311000.0 0.44 922129.0 322000.0 0.45 0.6304 1.0 2071364 Maybridge1_003930 COC(=O)c1scc(Br)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K15 compound treatment 969058.0 390000.0 0.55 989910.0 390000.0 0.54 0.7762 1.0 1075012 Maybridge1_003931 Cc1csc(N)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K16 compound treatment 889214.0 310000.0 0.44 949672.0 349000.0 0.49 0.6563 0.9987 1734344 Maybridge1_003932 OC(=O)c1ccccc1C(=O)Nc2sc3CCCCc3c2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K17 compound treatment 973836.0 395000.0 0.56 1045619.0 445000.0 0.62 0.836 0.9987 2071365 Maybridge1_003933 NC1=C(C(C(=C2Sc3ccccc3N21)C#N)c4ccc(C#N)cc4)c5nc6ccccc6s5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K18 compound treatment 900299.0 321000.0 0.46 989180.0 389000.0 0.54 0.7064 0.9963 1160325 Maybridge1_003934 Cc1ccc(C)n1c2sccc2C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K19 compound treatment 939756.0 360000.0 0.51 972954.0 373000.0 0.52 0.7301 1.0 1634867 Maybridge1_003935 COC(=O)c1sc(cc1N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K20 compound treatment 893931.0 315000.0 0.45 949449.0 349000.0 0.49 0.6608 0.9991 2071366 Maybridge1_003936 COC(=O)c1sc(cc1N)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K21 compound treatment 943944.0 365000.0 0.52 964315.0 364000.0 0.51 0.7257 0.9999 1701180 Maybridge1_003937 COc1ccc(cc1)c2cc(N)c(s2)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K22 compound treatment 905220.0 326000.0 0.46 955697.0 355000.0 0.5 0.6783 0.9994 2071367 Maybridge1_003938 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)NS(=O)(=O)c3ccc(C)cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K23 mock treatment 926713.0 347000.0 0.49 967746.0 368000.0 0.51 0.7118 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 K24 mock treatment 164967.0 -414000.0 -0.59 156553.0 -444000.0 -0.62 -0.8542 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L01 compound treatment 899939.0 321000.0 0.46 810603.0 210000.0 0.29 0.5299 0.9773 1674796 Maybridge1_003939 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L02 compound treatment 910546.0 331000.0 0.47 856315.0 256000.0 0.36 0.5857 0.9907 2071368 Maybridge1_003940 COc1ccc(/C=N/NC(=O)c2cnn(c2C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L03 compound treatment 982147.0 403000.0 0.57 939480.0 339000.0 0.47 0.7397 0.9955 1370879 Maybridge1_003941 COC(=O)c1cc(OC)c(OC)cc1n2c(C)ccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L04 compound treatment 937311.0 358000.0 0.51 871125.0 271000.0 0.38 0.6272 0.9892 2071369 Maybridge1_003942 Cc1ccc(/C=N/c2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L05 compound treatment 991546.0 412000.0 0.59 953471.0 353000.0 0.49 0.7629 0.9963 2071370 Maybridge1_003943 Cc1cc(C)c(NC(=S)NCc2ccco2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L06 compound treatment 978127.0 399000.0 0.57 871635.0 271000.0 0.38 0.6687 0.9807 2071371 Maybridge1_003944 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4cccs4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L07 compound treatment 936565.0 357000.0 0.51 929953.0 330000.0 0.46 0.6844 0.9988 2071372 Maybridge1_003945 Cn1nccc1NC(=O)Nc2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L08 compound treatment 942948.0 364000.0 0.52 853582.0 253000.0 0.35 0.6155 0.9828 2071373 Maybridge1_003946 Fc1cc(Br)c(F)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L09 compound treatment 960211.0 381000.0 0.54 937546.0 337000.0 0.47 0.7157 0.9975 1398582 Maybridge1_003947 Cn1nccc1NS(=O)(=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L10 compound treatment 883066.0 304000.0 0.43 875540.0 275000.0 0.38 0.577 0.9983 1537015 Maybridge1_003948 C1CN(CCN1)c2nc(ns2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L11 compound treatment 893997.0 315000.0 0.45 890830.0 291000.0 0.41 0.6031 0.9988 1723996 Maybridge1_003949 CC(C)Nc1ncnc2sc3CCCCc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L12 compound treatment 924150.0 345000.0 0.49 891052.0 291000.0 0.41 0.6336 0.9956 2071374 Maybridge1_003950 Cc1ccc(cc1)C(=O)C(O)(O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L13 compound treatment 949326.0 370000.0 0.53 916431.0 316000.0 0.44 0.6839 0.9961 1530996 Maybridge1_003951 COc1ccc(cc1)S(=O)(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L14 compound treatment 915016.0 336000.0 0.48 919731.0 320000.0 0.45 0.6527 0.9994 2071375 Maybridge1_003952 [O-][N+](=O)c1cccc(c1)C(=O)NC(=S)Nc2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L15 compound treatment 979369.0 400000.0 0.57 939581.0 339000.0 0.47 0.737 0.9958 1661227 Maybridge1_003953 CC(C)(C)c1ccc(cc1)c2cc(N)c(s2)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L16 compound treatment 914912.0 336000.0 0.48 926740.0 327000.0 0.46 0.6595 0.9997 1680767 Maybridge1_003954 CC(C)c1ccc(NC(=S)NC2CC3CC2C4C=CCC34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L17 compound treatment 932746.0 353000.0 0.5 966081.0 366000.0 0.51 0.7162 1.0 1594290 Maybridge1_003955 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L18 compound treatment 897806.0 319000.0 0.45 837589.0 237000.0 0.33 0.5544 0.9881 2071376 Maybridge1_003956 CC(C)c1ccc(NC(=O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L19 compound treatment 953385.0 374000.0 0.53 967407.0 367000.0 0.51 0.7383 0.9998 1728790 Maybridge1_003957 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L20 compound treatment 876326.0 297000.0 0.42 900108.0 300000.0 0.42 0.5944 1.0 2071377 Maybridge1_003958 Cc1onc(c1C(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L21 compound treatment 1013784.0 434000.0 0.62 962767.0 363000.0 0.51 0.7944 0.995 2071378 Maybridge1_003959 Cc1ccc(cc1)C(=O)NNc2ncnc3cc(sc23)c4ccc(cc4)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L22 compound treatment 934371.0 355000.0 0.5 916953.0 317000.0 0.44 0.6694 0.9978 1122099 Maybridge1_003960 OCCN1CCN(CN2C(=O)C3(OCCO3)c4ccccc24)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L23 mock treatment 953507.0 374000.0 0.53 927969.0 328000.0 0.46 0.6995 0.9971 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 L24 mock treatment 138239.0 -441000.0 -0.63 168036.0 -432000.0 -0.6 -0.8697 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M01 compound treatment 869117.0 290000.0 0.41 822857.0 223000.0 0.31 0.511 0.9903 2071379 Maybridge1_003961 CS/C(=N/C(=O)c1c(Cl)cccc1Cl)/NCCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M02 compound treatment 871393.0 292000.0 0.42 836936.0 237000.0 0.33 0.5272 0.9935 2071380 Maybridge1_003962 Cc1csc(C(=O)NN)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M03 compound treatment 943353.0 364000.0 0.52 932107.0 332000.0 0.46 0.6934 0.9984 1636017 Maybridge1_003963 COC(=O)CCNc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M04 compound treatment 931891.0 353000.0 0.5 906214.0 306000.0 0.43 0.6563 0.9968 2071381 Maybridge1_003964 CCCc1c(cnn1c2ccc(Cl)cc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M05 compound treatment 945248.0 366000.0 0.52 926508.0 326000.0 0.46 0.6898 0.9978 2071382 Maybridge1_003965 CC(C)(C)c1cc(/C=C/2\Cc3ccccc3C2=O)cc(c1O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M06 compound treatment 914037.0 335000.0 0.48 885455.0 285000.0 0.4 0.6179 0.996 2071383 Maybridge1_003966 CCOC(=O)c1c[nH]c(=O)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M07 compound treatment 990103.0 411000.0 0.58 961723.0 361000.0 0.5 0.7696 0.9973 2071384 Maybridge1_003967 NC1=C(C#N)C(C(C#N)C#N)c2cc(Cl)ccc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M08 compound treatment 855632.0 276000.0 0.39 911269.0 311000.0 0.43 0.5846 0.9988 2071385 Maybridge1_003968 CC(=O)c1sc(cc1N)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M09 compound treatment 901005.0 322000.0 0.46 929461.0 329000.0 0.46 0.6482 1.0 2071386 Maybridge1_003969 COC(=O)C(C#N)C1C(=C(N)Oc2ccccc12)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M10 compound treatment 891505.0 312000.0 0.44 878559.0 278000.0 0.39 0.5884 0.9978 2071387 Maybridge1_003970 OC(=O)c1cnn(c1C(F)(F)F)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M11 compound treatment 927719.0 348000.0 0.5 930787.0 331000.0 0.46 0.6764 0.9994 2071388 Maybridge1_003971 Cc1onc(c1C(=O)ON=C2C3CC4CC(C3)CC2C4)c5ccccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M12 compound treatment 860919.0 282000.0 0.4 915424.0 315000.0 0.44 0.594 0.9989 2071389 Maybridge1_003972 CCCc1c(cnn1c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M13 compound treatment 935838.0 357000.0 0.51 940194.0 340000.0 0.47 0.6938 0.9994 1130128 Maybridge1_003973 Clc1ccc(c(Cl)c1)c2cc3C(=O)c4ccccc4-c3nn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M14 compound treatment 928220.0 349000.0 0.5 941248.0 341000.0 0.48 0.6872 0.9998 2071390 Maybridge1_003974 CC(C)(C)c1cc(N)c(C#N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M15 compound treatment 933531.0 354000.0 0.5 928004.0 328000.0 0.46 0.6795 0.9988 1355900 Maybridge1_003975 COC(=O)c1sccc1NC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M16 compound treatment 865867.0 287000.0 0.41 903661.0 303000.0 0.42 0.5874 0.9998 3177423 Maybridge1_003976 Cc1ccc(cc1)S(=O)(=O)O.N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M17 compound treatment 901737.0 322000.0 0.46 924557.0 324000.0 0.45 0.6441 1.0 2071392 Maybridge1_003977 COC(=O)c1sc(cc1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M18 compound treatment 878199.0 299000.0 0.43 929479.0 329000.0 0.46 0.6253 0.9993 2071393 Maybridge1_003978 C/C(=N\O)/C(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M19 compound treatment 935132.0 356000.0 0.51 967649.0 367000.0 0.51 0.7202 1.0 2071394 Maybridge1_003979 CCOC(=O)c1c[nH]nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M20 compound treatment 904958.0 326000.0 0.46 902563.0 302000.0 0.42 0.6256 0.9989 1358367 Maybridge1_003980 NS(=O)(=O)c1cccc(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M21 compound treatment 932521.0 353000.0 0.5 953187.0 353000.0 0.49 0.7033 0.9999 2071395 Maybridge1_003981 CNNC(=O)Cc1ccc(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M22 compound treatment 883826.0 305000.0 0.43 932433.0 332000.0 0.46 0.6339 0.9994 2071396 Maybridge1_003982 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M23 mock treatment 922279.0 343000.0 0.49 922111.0 322000.0 0.45 0.6623 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 M24 mock treatment 686233.0 107000.0 0.15 747905.0 148000.0 0.21 0.2532 0.9889 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N01 compound treatment 915771.0 336000.0 0.48 843464.0 243000.0 0.34 0.5782 0.9858 2071397 Maybridge1_003983 Cn1nccc1NC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N02 compound treatment 899687.0 320000.0 0.46 889560.0 289000.0 0.4 0.6075 0.9982 2071398 Maybridge1_003984 [O-][N+](=O)c1ccc(cc1)n2ncc(C(=O)N/N=C/c3ccc(C#N)cc3)c2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N03 compound treatment 962050.0 383000.0 0.54 925585.0 325000.0 0.45 0.7058 0.9959 1532326 Maybridge1_003985 Cc1ccc(C)n1c2sc3CCCCc3c2C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N04 compound treatment 940652.0 361000.0 0.51 854944.0 255000.0 0.36 0.6146 0.9838 2071399 Maybridge1_003986 CNC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N05 compound treatment 971104.0 392000.0 0.56 930248.0 330000.0 0.46 0.7195 0.9955 2071400 Maybridge1_003987 NC(=S)NCc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N06 compound treatment 883770.0 304000.0 0.43 887718.0 287000.0 0.4 0.5897 0.9993 2071401 Maybridge1_003988 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4ccco4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N07 compound treatment 976962.0 398000.0 0.57 952755.0 353000.0 0.49 0.7475 0.9976 1669792 Maybridge1_003989 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N08 compound treatment 942019.0 363000.0 0.52 864518.0 264000.0 0.37 0.6254 0.9864 1239102 Maybridge1_003990 OC(=O)C(Cc1ccccc1)NC(=O)c2ccc(cc2)C(=O)NC(Cc3ccccc3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N09 compound treatment 986040.0 407000.0 0.58 957565.0 357000.0 0.5 0.7614 0.9972 1681140 Maybridge1_003991 Cc1c(Cl)cccc1S(=O)(=O)Nc2ccnn2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N10 compound treatment 940304.0 361000.0 0.51 936828.0 337000.0 0.47 0.695 0.999 1531989 Maybridge1_003992 OC(=O)CSCC(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N11 compound treatment 981727.0 402000.0 0.57 958115.0 358000.0 0.5 0.7576 0.9977 1552824 Maybridge1_003993 COC(=O)c1ccccc1NC(=O)c2c(F)cccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N12 compound treatment 912483.0 333000.0 0.47 929981.0 330000.0 0.46 0.6603 0.9999 1634253 Maybridge1_003994 CCOC(=O)c1ccc(NC(=S)NCCc2ccc(OC)c(OC)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N13 compound treatment 931075.0 352000.0 0.5 941248.0 341000.0 0.48 0.6901 0.9997 1325092 Maybridge1_003995 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N14 compound treatment 880538.0 301000.0 0.43 881705.0 281000.0 0.39 0.5805 0.9991 1305504 Maybridge1_003996 COc1ccc(CCNC(=S)NC2CC3CC2C=C3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N15 compound treatment 1002937.0 424000.0 0.6 934073.0 334000.0 0.47 0.7552 0.9919 1295871 Maybridge1_003997 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Nc3cc(C)cc(C)c3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N16 compound treatment 918585.0 339000.0 0.48 913389.0 313000.0 0.44 0.65 0.9988 2071402 Maybridge1_003998 Clc1ccc(cc1)c2nc(cs2)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N17 compound treatment 943640.0 364000.0 0.52 960966.0 361000.0 0.5 0.7221 0.9999 1660249 Maybridge1_003999 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(F)cc3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N18 compound treatment 883842.0 305000.0 0.43 846422.0 246000.0 0.34 0.549 0.9934 2071403 Maybridge1_004000 FC(F)(F)Oc1ccc(NC(=O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N19 compound treatment 957023.0 378000.0 0.54 933640.0 333000.0 0.47 0.7086 0.9974 331 Maybridge1_004001 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N20 compound treatment 894403.0 315000.0 0.45 918734.0 319000.0 0.44 0.631 1.0 1381468 Maybridge1_004002 CC(C)(CC(=O)O)CC(=O)Nc1ccc2OCCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N21 compound treatment 968066.0 389000.0 0.55 968591.0 368000.0 0.51 0.7542 0.9993 1577705 Maybridge1_004003 CC(C)(C)c1cc2ncnc(N3CCOCC3)c2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N22 compound treatment 915354.0 336000.0 0.48 921979.0 322000.0 0.45 0.6552 0.9995 2071404 Maybridge1_004004 COc1ccc(cc1)c2ccnc(SCC(=O)Nc3ccccc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N23 mock treatment 935720.0 356000.0 0.51 955990.0 356000.0 0.5 0.7093 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 N24 mock treatment 669104.0 89800.0 0.13 591520.0 -8700.0 -0.01 0.0817 0.637 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O01 compound treatment 891307.0 312000.0 0.44 816325.0 216000.0 0.3 0.5269 0.9822 2071405 Maybridge1_004005 CSC(=C(C#N)c1ccccc1)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O02 compound treatment 842633.0 263000.0 0.37 841744.0 242000.0 0.34 0.503 0.9986 2071406 Maybridge1_004006 OC(=O)c1sccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O03 compound treatment 914316.0 335000.0 0.48 886618.0 286000.0 0.4 0.6193 0.9962 2071407 Maybridge1_004007 C/C(=N\O)/C=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O04 compound treatment 903636.0 324000.0 0.46 856072.0 256000.0 0.36 0.5785 0.992 2071408 Maybridge1_004008 OC(=O)c1cnn(c1C(F)(F)F)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O05 compound treatment 929863.0 351000.0 0.5 883454.0 283000.0 0.4 0.6318 0.9934 2071409 Maybridge1_004009 [O-][N+](=O)c1ccc(OC(=O)OC2(CC3CC4CC(C3)C2)C4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O06 compound treatment 883737.0 304000.0 0.43 822956.0 223000.0 0.31 0.5258 0.9867 2071410 Maybridge1_004010 CC(C)(C)c1cc(N)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O07 compound treatment 949326.0 370000.0 0.53 891925.0 292000.0 0.41 0.6598 0.9919 2071411 Maybridge1_004011 NC1=C(C#N)C(C(C#N)C#N)c2cc(Br)ccc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O08 compound treatment 889157.0 310000.0 0.44 906478.0 306000.0 0.43 0.6136 0.9999 2071412 Maybridge1_004012 COC(=O)c1scc(Br)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O09 compound treatment 942359.0 363000.0 0.52 844963.0 245000.0 0.34 0.6064 0.9798 2071413 Maybridge1_004013 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccccc12)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O10 compound treatment 863506.0 284000.0 0.4 828597.0 228000.0 0.32 0.511 0.993 1117875 Maybridge1_004014 COC(=O)c1sc(cc1N)c2ccc(CC(C)C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O11 compound treatment 914816.0 336000.0 0.48 871706.0 271000.0 0.38 0.6051 0.9934 2071414 Maybridge1_004015 CC/1=C2CCCC2CC\C1=N/NC(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O12 compound treatment 882961.0 304000.0 0.43 890174.0 290000.0 0.4 0.5913 0.9995 2071415 Maybridge1_004016 CC(=O)c1sccc1NC(=O)c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O13 compound treatment 940111.0 361000.0 0.51 898406.0 298000.0 0.42 0.6569 0.9946 2071416 Maybridge1_004017 COC(=O)c1sccc1NC(=S)Nc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O14 compound treatment 885114.0 306000.0 0.43 891513.0 291000.0 0.41 0.5948 0.9994 2071417 Maybridge1_004018 Clc1ccc(Cc2nn[nH]n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O15 compound treatment 954421.0 375000.0 0.53 927790.0 328000.0 0.46 0.7003 0.997 1415121 Maybridge1_004019 COC(=O)c1sccc1NC(=O)c2c(F)cccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O16 compound treatment 895423.0 316000.0 0.45 887384.0 287000.0 0.4 0.6011 0.9983 2071418 Maybridge1_004020 COC(=O)c1sccc1NC(=S)Nc2ccsc2C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O17 compound treatment 912043.0 333000.0 0.47 882824.0 283000.0 0.39 0.6133 0.9959 2071419 Maybridge1_004021 NNC(=O)c1sccc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O18 compound treatment 864488.0 285000.0 0.41 870960.0 271000.0 0.38 0.5538 0.9994 2071420 Maybridge1_004022 [O-][N+](=O)c1ccc(cc1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O19 compound treatment 1032239.0 453000.0 0.64 1038121.0 438000.0 0.61 0.8873 0.9996 2071421 Maybridge1_004023 FC(F)(F)c1cc(NC(=O)N/C=C/c2ccco2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O20 compound treatment 881391.0 302000.0 0.43 870983.0 271000.0 0.38 0.5708 0.9979 2071422 Maybridge1_004024 Cc1c(sc2cc(sc12)C(C)(C)C)C(=O)O/N=C/c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O21 compound treatment 894064.0 315000.0 0.45 891702.0 291000.0 0.41 0.604 0.9988 2071423 Maybridge1_004025 Nc1cc(nc(N)n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O22 compound treatment 866046.0 287000.0 0.41 894859.0 295000.0 0.41 0.5789 1.0 1637926 Maybridge1_004026 COC(=O)c1cc(OC)c(OC)cc1NS(=O)(=O)c2ccc(OC)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O23 mock treatment 886821.0 308000.0 0.44 903610.0 303000.0 0.42 0.6084 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 O24 mock treatment 514776.0 -64500.0 -0.09 521229.0 -79000.0 -0.11 -0.1428 -0.9959 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P01 compound treatment 890239.0 311000.0 0.44 805061.0 205000.0 0.29 0.5147 0.9777 2071424 Maybridge1_004027 CCOC(=O)CN(C)S(=O)(=O)c1ccsc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P02 compound treatment 876796.0 298000.0 0.42 830158.0 230000.0 0.32 0.5259 0.9907 2071425 Maybridge1_004028 Cc1nc(Cc2ccc(cc2)[N+](=O)[O-])no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P03 compound treatment 890354.0 311000.0 0.44 830993.0 231000.0 0.32 0.5404 0.9878 1678568 Maybridge1_004029 COC(=O)CSc1ncnc2cc(OC)c(OC)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P04 compound treatment 900064.0 321000.0 0.46 856801.0 257000.0 0.36 0.5756 0.9928 2071426 Maybridge1_004030 Nc1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P05 compound treatment 921320.0 342000.0 0.49 832591.0 232000.0 0.32 0.5731 0.9805 2071427 Maybridge1_004031 Nc1ncnc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P06 compound treatment 930959.0 352000.0 0.5 863042.0 263000.0 0.37 0.6128 0.9883 2071428 Maybridge1_004032 COC(=O)c1csc2c(cc(nc12)N3CCN(CC3)C(=O)c4cc(Cl)cc(Cl)c4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P07 compound treatment 897464.0 318000.0 0.45 852280.0 252000.0 0.35 0.5685 0.9922 1607107 Maybridge1_004033 CCCc1c(cnn1c2ccccc2)C(=O)Nc3ccnn3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P08 compound treatment 886253.0 307000.0 0.44 853508.0 253000.0 0.35 0.5585 0.9945 2071429 Maybridge1_004034 Fc1cc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)c(F)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P09 compound treatment 902571.0 323000.0 0.46 851993.0 252000.0 0.35 0.5734 0.9912 2071430 Maybridge1_004035 Cn1nccc1NC(=O)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P10 compound treatment 908585.0 329000.0 0.47 842147.0 242000.0 0.34 0.5697 0.9871 2071431 Maybridge1_004036 COC(=O)c1ccccc1CSc2nccc(n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P11 compound treatment 911853.0 333000.0 0.47 849206.0 249000.0 0.35 0.58 0.9885 1214297 Maybridge1_004037 COC(=O)c1ccccc1NC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P12 compound treatment 931065.0 352000.0 0.5 859800.0 260000.0 0.36 0.6097 0.9874 1335445 Maybridge1_004038 COc1ccc(CCNC(=S)Nc2ccc(C)cc2C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P13 compound treatment 933757.0 354000.0 0.5 865658.0 265000.0 0.37 0.6182 0.9885 1232563 Maybridge1_004039 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2ccccc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P14 compound treatment 887449.0 308000.0 0.44 867548.0 267000.0 0.37 0.5735 0.9968 1130038 Maybridge1_004040 S=C(NC1CC2CC1C=C2)NC3CCCCCCCCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P15 compound treatment 926553.0 347000.0 0.49 853839.0 254000.0 0.35 0.5993 0.9866 2071432 Maybridge1_004041 Cn1ncc(Br)c1NC(=O)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P16 compound treatment 926305.0 347000.0 0.49 870810.0 271000.0 0.38 0.6158 0.9912 2071433 Maybridge1_004042 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P17 compound treatment 914764.0 335000.0 0.48 864310.0 264000.0 0.37 0.5978 0.9918 1213717 Maybridge1_004043 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3cccs3)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P18 compound treatment 881495.0 302000.0 0.43 859448.0 259000.0 0.36 0.5595 0.9963 2071434 Maybridge1_004044 [O-][N+](=O)c1ccc(nc1)N2CCN(CC(=O)Nc3ccc4OCOc4c3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P19 compound treatment 909337.0 330000.0 0.47 887335.0 287000.0 0.4 0.615 0.9969 1179493 Maybridge1_004045 COc1cc2ncnc(Nc3ccc(F)c(F)c3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P20 compound treatment 904297.0 325000.0 0.46 883876.0 284000.0 0.4 0.6065 0.997 2071435 Maybridge1_004046 COC(=O)c1sccc1NC(=O)CSCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P21 compound treatment 895897.0 317000.0 0.45 882300.0 282000.0 0.39 0.5965 0.9977 2071436 Maybridge1_004047 Cn1ncc(C(=O)O/N=C/c2ccc(Cl)cc2Cl)c1n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P22 compound treatment 865248.0 286000.0 0.41 876549.0 276000.0 0.39 0.5601 0.9996 1264484 Maybridge1_004048 CCOC(=O)C1C(CC(=CC1=O)c2cccs2)c3ccc(OC)c(OC)c3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P23 mock treatment 877569.0 298000.0 0.42 861997.0 262000.0 0.37 0.5581 0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.552 P24 mock treatment 307701.0 -272000.0 -0.39 595243.0 -4980.0 -0.01 -0.278 -0.7197 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A01 mock treatment 855639.0 -7180.0 -0.01 797040.0 -28400.0 -0.04 -0.0352 -0.8613 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A02 mock treatment 853492.0 -9320.0 -0.01 793928.0 -31500.0 -0.04 -0.0404 -0.8813 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A03 compound treatment 858584.0 -4230.0 -0.01 836262.0 10900.0 0.02 0.0065 0.396 2071437 Maybridge1_004049 ClC(Cl)(Cl)C(=O)Nc1c(Br)c(nn1c2ccccc2)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A04 compound treatment 875270.0 12500.0 0.02 834860.0 9450.0 0.01 0.0218 0.9894 1036161 Maybridge1_004050 Clc1ccc(C=C2c3ccccc3-c4ccccc24)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A05 compound treatment 883747.0 20900.0 0.03 848580.0 23200.0 0.03 0.0439 0.9992 2071438 Maybridge1_004051 Cc1ccc(cc1)S(=O)(=O)CCSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A06 compound treatment 912207.0 49400.0 0.07 883423.0 58000.0 0.08 0.1069 0.9975 2071439 Maybridge1_004052 CCCc1cc(O)nc(SCc2ccccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A07 compound treatment 937692.0 74900.0 0.11 884466.0 59100.0 0.08 0.1335 0.9919 1618329 Maybridge1_004053 Cc1cc2[nH]c(cc(=O)n2n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A08 compound treatment 925567.0 62800.0 0.09 916544.0 91100.0 0.13 0.153 0.985 2071440 Maybridge1_004054 Cn1nc(nc1O)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A09 compound treatment 914426.0 51600.0 0.07 915727.0 90300.0 0.13 0.141 0.9669 2071441 Maybridge1_004055 Cc1cc(NC(=O)Nc2ccccc2)n(n1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A10 compound treatment 930948.0 68100.0 0.1 901317.0 75900.0 0.11 0.1434 0.999 2071442 Maybridge1_004056 COC(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A11 compound treatment 893915.0 31100.0 0.04 913053.0 87600.0 0.12 0.1177 0.9055 2071443 Maybridge1_004057 CNC(=O)Nc1cc(C)nn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A12 compound treatment 889575.0 26800.0 0.04 928772.0 103000.0 0.14 0.1288 0.8642 2071444 Maybridge1_004058 CS/C(=N\C#N)/Nc1cccc(SC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A13 compound treatment 917049.0 54200.0 0.08 921759.0 96400.0 0.13 0.1496 0.9653 2071445 Maybridge1_004059 OCc1ccccc1C(=O)N/N=C/c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A14 compound treatment 870206.0 7390.0 0.01 936529.0 111000.0 0.15 0.117 0.7533 1006104 Maybridge1_004060 Cc1cc(=O)oc2cc(O)cc(O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A15 compound treatment 925035.0 62200.0 0.09 948032.0 123000.0 0.17 0.1835 0.953 2071446 Maybridge1_004061 Fc1ccc(NC(=S)N(CCC#N)Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A16 compound treatment 914834.0 52000.0 0.07 947324.0 122000.0 0.17 0.1725 0.9305 1043641 Maybridge1_004062 CCCCCCCOc1ccc(cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A17 compound treatment 928754.0 65900.0 0.09 970723.0 145000.0 0.2 0.2096 0.9387 1282423 Maybridge1_004063 CSc1cccc(NC2OC(=O)c3ccccc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A18 compound treatment 921249.0 58400.0 0.08 925336.0 99900.0 0.14 0.1573 0.9695 1931114 Maybridge1_004064 [O-][N+](=O)c1ccc(cc1)c2ccc(I)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A19 compound treatment 945709.0 82900.0 0.12 916196.0 90800.0 0.13 0.1729 0.9994 1159824 Maybridge1_004065 CCOC(=O)c1ccc(N2CCOCC2)c(NS(=O)(=O)c3ccc(F)cc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A20 compound treatment 923770.0 61000.0 0.09 895906.0 70500.0 0.1 0.1308 0.998 1557241 Maybridge1_004066 CCn1c(O)cc(C)c(C#N)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A21 compound treatment 936084.0 73300.0 0.1 852980.0 27600.0 0.04 0.1009 0.9082 1374202 Maybridge1_004067 CCOC(=O)c1ccc(N2CCOCC2)c(N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A22 compound treatment 861480.0 -1330.0 0.0 843133.0 17700.0 0.02 0.0161 0.6509 1100255 Maybridge1_004068 Clc1ccc(C2NC(=O)Cc3ccccc23)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A23 compound treatment 853583.0 -9230.0 -0.01 847097.0 21700.0 0.03 0.0121 0.3672 1526172 Maybridge1_004069 O=C1OC(Nc2ccccc2SCc3ccc(C#N)cc3)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 A24 compound treatment 174868.0 -688000.0 -0.98 146505.0 -679000.0 -0.95 -1.3613 -0.9999 2071447 Maybridge1_004070 Sc1nnc(SCCSc2nnc(S)s2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B01 mock treatment 860421.0 -2390.0 0.0 767804.0 -57600.0 -0.08 -0.0592 -0.7364 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B02 mock treatment 858828.0 -3990.0 -0.01 805511.0 -19900.0 -0.03 -0.0236 -0.8343 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B03 compound treatment 897930.0 35100.0 0.05 859425.0 34000.0 0.05 0.0689 0.9997 1069883 Maybridge1_004071 CS(=O)(=O)OC1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B04 compound treatment 903628.0 40800.0 0.06 834570.0 9160.0 0.01 0.0501 0.8426 1103910 Maybridge1_004072 COc1ccc(O)c(c1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B05 compound treatment 942295.0 79500.0 0.11 926953.0 102000.0 0.14 0.1801 0.9938 2071448 Maybridge1_004073 COc1cccc2c(OC(=O)C)coc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B06 compound treatment 918331.0 55500.0 0.08 885481.0 60100.0 0.08 0.1151 0.9996 2071449 Maybridge1_004074 CCO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B07 compound treatment 983058.0 120000.0 0.17 955716.0 130000.0 0.18 0.2494 0.9995 2071450 Maybridge1_004075 [O-][N+](=O)c1ccc(cc1)C(=O)O/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B08 compound treatment 951769.0 89000.0 0.13 938722.0 113000.0 0.16 0.2012 0.9939 1611061 Maybridge1_004076 CC(C)C(=O)Nc1ncnc2[nH]cnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B09 compound treatment 970148.0 107000.0 0.15 949354.0 124000.0 0.17 0.2302 0.9981 1145454 Maybridge1_004077 Cc1ccc(cc1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B10 compound treatment 944194.0 81400.0 0.12 932927.0 108000.0 0.15 0.1879 0.9918 2071451 Maybridge1_004078 C(=C/c1ccncc1)\c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B11 compound treatment 931532.0 68700.0 0.1 968805.0 143000.0 0.2 0.2105 0.9457 2071452 Maybridge1_004079 O=C1CC23CC(=O)CC3(C1)CCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B12 compound treatment 947575.0 84800.0 0.12 906018.0 80600.0 0.11 0.1647 0.9994 1651448 Maybridge1_004080 COc1ccc(cc1)c2cc(C(=O)O)c3ccc(C)cc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B13 compound treatment 919512.0 56700.0 0.08 864805.0 39400.0 0.05 0.0959 0.9825 2071453 Maybridge1_004081 Nc1c(Oc2ccccc2)cc(O)c3C(=O)c4ccccc4C(=O)c13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B14 compound treatment 967252.0 104000.0 0.15 978742.0 153000.0 0.21 0.2562 0.9841 1287428 Maybridge1_004082 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3ccc(s3)c4ccccn4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B15 compound treatment 900837.0 38000.0 0.05 1003177.0 178000.0 0.25 0.2136 0.8415 2071454 Maybridge1_004083 CN1CC(=O)N=C1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B16 compound treatment 938951.0 76100.0 0.11 961262.0 136000.0 0.19 0.2105 0.9648 1639300 Maybridge1_004084 O=C(NCc1ccc2OCOc2c1)NC3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B17 compound treatment 975766.0 113000.0 0.16 962278.0 137000.0 0.19 0.2486 0.9963 1269668 Maybridge1_004085 COc1ccccc1N2CCN(CC2)C(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B18 compound treatment 871415.0 8600.0 0.01 903187.0 77800.0 0.11 0.0854 0.7819 2071455 Maybridge1_004086 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)Nc3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B19 compound treatment 942361.0 79500.0 0.11 948768.0 123000.0 0.17 0.2016 0.9793 2071456 Maybridge1_004087 Cn1c2CCC/C(=N\OC(=O)C3CCCCC3)/c2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B20 compound treatment 919407.0 56600.0 0.08 864603.0 39200.0 0.05 0.0956 0.9822 2071457 Maybridge1_004088 Cc1cc(nn1C(C)(C)C)C(=O)NNC(=O)C2CCN(CC2)c3nccc(n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B21 compound treatment 955821.0 93000.0 0.13 897821.0 72400.0 0.1 0.1649 0.9911 1010925 Maybridge1_004089 Sc1nc2ccccc2nc1S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B22 compound treatment 901636.0 38800.0 0.06 890370.0 65000.0 0.09 0.1031 0.9718 1460321 Maybridge1_004090 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B23 compound treatment 920494.0 57700.0 0.08 886635.0 61200.0 0.09 0.1184 0.9998 1196658 Maybridge1_004091 ON=C1CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 B24 compound treatment 166957.0 -696000.0 -0.99 130297.0 -695000.0 -0.97 -1.3853 -0.9999 1230437 Maybridge1_004092 OC(CSc1ccccc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C01 mock treatment 769230.0 -93600.0 -0.13 727716.0 -97700.0 -0.14 -0.1904 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C02 mock treatment 786612.0 -76200.0 -0.11 792897.0 -32500.0 -0.05 -0.1087 -0.9252 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C03 compound treatment 821736.0 -41100.0 -0.06 848288.0 22900.0 0.03 -0.0187 -0.2816 1637319 Maybridge1_004093 CC(C)(C)C(=O)Nc1cc(nn1c2ccccc2)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C04 compound treatment 818442.0 -44400.0 -0.06 850140.0 24700.0 0.03 -0.0202 -0.2813 2071458 Maybridge1_004094 O/N=C(/c1ccccc1)\c2ccccc2\N=C\c3cc(Cl)cc(Cl)c3O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C05 compound treatment 854209.0 -8610.0 -0.01 875318.0 49900.0 0.07 0.0406 0.574 2071459 Maybridge1_004095 Cc1ccc(cc1)S(=O)(=O)CCSc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C06 compound treatment 834743.0 -28100.0 -0.04 820014.0 -5390.0 -0.01 -0.0335 -0.8258 2071460 Maybridge1_004096 Nc1ncnc(SCc2c(F)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C07 compound treatment 885139.0 22300.0 0.03 890190.0 64800.0 0.09 0.0863 0.9015 2071461 Maybridge1_004097 Nc1cc(n[nH]1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C08 compound treatment 871455.0 8640.0 0.01 879937.0 54500.0 0.08 0.0625 0.8108 2071462 Maybridge1_004098 CNC(=O)NNC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C09 compound treatment 890765.0 28000.0 0.04 917886.0 92500.0 0.13 0.1193 0.884 2071463 Maybridge1_004099 Cc1cc(NC(=O)C(C)(C)C)n(C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C10 compound treatment 820389.0 -42400.0 -0.06 840330.0 14900.0 0.02 -0.0279 -0.4379 1569859 Maybridge1_004100 CC(C)c1ccc(Nc2cc(O)nn2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C11 compound treatment 824163.0 -38700.0 -0.05 919644.0 94200.0 0.13 0.0541 0.3795 2071464 Maybridge1_004101 Cc1cc(NC(=O)c2ccccc2)n(C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C12 compound treatment 845392.0 -17400.0 -0.02 867984.0 42600.0 0.06 0.0245 0.3803 2071465 Maybridge1_004102 CN(C)/C=N/S(=O)(=O)c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C13 compound treatment 893386.0 30600.0 0.04 864643.0 39200.0 0.05 0.0694 0.9935 2071466 Maybridge1_004103 COc1ccc(cc1)C(=O)NNC(=O)C2C(C3CC2C=C3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C14 compound treatment 874335.0 11500.0 0.02 907465.0 82100.0 0.11 0.0925 0.8002 1005598 Maybridge1_004104 CC[n+]1c(C)ccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C15 compound treatment 904499.0 41700.0 0.06 858752.0 33300.0 0.05 0.0748 0.9928 2071467 Maybridge1_004105 C/C(=N/NC(=O)N)/c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C16 compound treatment 877944.0 15100.0 0.02 888552.0 63100.0 0.09 0.0775 0.8547 1011181 Maybridge1_004106 c1ccc2c(c1)ccc3ncccc32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C17 compound treatment 867026.0 4210.0 0.01 922040.0 96600.0 0.13 0.0995 0.7378 1703659 Maybridge1_004107 COc1cc2CCN=C(c3ccccc3NC(=O)c4ccc(F)cc4)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C18 compound treatment 822942.0 -39900.0 -0.06 879047.0 53600.0 0.07 0.0128 0.1364 1009943 Maybridge1_004108 O=C(Nc1cccc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C19 compound treatment 882615.0 19800.0 0.03 908174.0 82800.0 0.12 0.1015 0.8545 1418039 Maybridge1_004109 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C20 compound treatment 830465.0 -32300.0 -0.05 764322.0 -61100.0 -0.09 -0.0928 -0.9582 1153807 Maybridge1_004110 OC(CN1CCCC1)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C21 compound treatment 863112.0 297.0 0.0 866707.0 41300.0 0.06 0.041 0.7123 2071468 Maybridge1_004111 CCOC(=O)c1ccc(N2CCOCC2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C22 compound treatment 835018.0 -27800.0 -0.04 838302.0 12900.0 0.02 -0.0152 -0.3508 1373411 Maybridge1_004112 Clc1ccccc1C2NC(=O)Cc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C23 compound treatment 829416.0 -33400.0 -0.05 802492.0 -22900.0 -0.03 -0.0562 -0.9814 1111528 Maybridge1_004113 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 C24 compound treatment 146820.0 -716000.0 -1.02 164652.0 -661000.0 -0.92 -1.3716 -0.9988 2071469 Maybridge1_004114 C(CSc1nnc[nH]1)Sc2nnc[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D01 mock treatment 868602.0 5790.0 0.01 790502.0 -34900.0 -0.05 -0.0286 -0.5793 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D02 mock treatment 864782.0 1970.0 0.0 857936.0 32500.0 0.05 0.0341 0.7493 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D03 compound treatment 874549.0 11700.0 0.02 896654.0 71200.0 0.1 0.0821 0.8144 1090692 Maybridge1_004115 CC1(CC2(C)CC3(C)C1)CC(Br)(C2)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D04 compound treatment 908165.0 45400.0 0.06 901308.0 75900.0 0.11 0.1205 0.9718 2071470 Maybridge1_004116 Ic1cc(C#N)cc(I)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D05 compound treatment 994979.0 132000.0 0.19 995852.0 170000.0 0.24 0.301 0.9932 2071471 Maybridge1_004117 Cc1ccc(cc1)S(=O)(=O)OCC(C)(C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D06 compound treatment 944858.0 82000.0 0.12 917790.0 92400.0 0.13 0.1736 0.9988 2071472 Maybridge1_004118 CC(=O)OC[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D07 compound treatment 983608.0 121000.0 0.17 952061.0 127000.0 0.18 0.2464 0.9999 2071473 Maybridge1_004119 Brc1ccccc1C(=O)O/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D08 compound treatment 960001.0 97200.0 0.14 945608.0 120000.0 0.17 0.2163 0.9954 2071474 Maybridge1_004120 CC(=O)O[C@@H]1CO[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D09 compound treatment 988806.0 126000.0 0.18 1016301.0 191000.0 0.27 0.315 0.9814 2071475 Maybridge1_004121 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D10 compound treatment 981009.0 118000.0 0.17 1010929.0 186000.0 0.26 0.3018 0.9782 1269639 Maybridge1_004122 CCC(=O)Nc1cccc2c(NC(=O)CC)cccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D11 compound treatment 932755.0 69900.0 0.1 936283.0 111000.0 0.15 0.1797 0.9772 1920748 Maybridge1_004123 CC(C)(C)c1cc(nc(N)n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D12 compound treatment 927879.0 65100.0 0.09 930743.0 105000.0 0.15 0.1693 0.9752 2071476 Maybridge1_004124 COc1ccc(Br)cc1/C=N/N=C\2/C(=O)Nc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D13 compound treatment 1002666.0 140000.0 0.2 971856.0 146000.0 0.2 0.2851 0.9999 2071477 Maybridge1_004125 CC(=O)C1C(=O)c2cccc([N+](=O)[O-])c2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D14 compound treatment 971837.0 109000.0 0.16 1009682.0 184000.0 0.26 0.2914 0.9707 2071478 Maybridge1_004126 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSc4nccc(n4)c5cccs5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D15 compound treatment 988676.0 126000.0 0.18 1000412.0 175000.0 0.24 0.2992 0.9884 2071479 Maybridge1_004127 CCOC(=O)/C(=N/Nc1ccc(C)cc1C)/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D16 compound treatment 966613.0 104000.0 0.15 1013442.0 188000.0 0.26 0.2898 0.963 1309532 Maybridge1_004128 Cc1ccc(NC(=O)Nc2ccc3COC(=O)c3c2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D17 compound treatment 957774.0 95000.0 0.14 1042807.0 217000.0 0.3 0.3099 0.9336 2071480 Maybridge1_004129 O=c1[nH]ccn1Cc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D18 compound treatment 937692.0 74900.0 0.11 993997.0 169000.0 0.24 0.2416 0.9358 2071481 Maybridge1_004130 OC(=O)CSCC(=O)Nc1ccc(Br)c(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D19 compound treatment 993752.0 131000.0 0.19 1015094.0 190000.0 0.26 0.3187 0.9852 2071482 Maybridge1_004131 Cn1c2CCC/C(=N\OC(=O)c3ccc(Cl)cc3Cl)/c2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D20 compound treatment 962220.0 99400.0 0.14 949020.0 124000.0 0.17 0.2219 0.9951 2071483 Maybridge1_004132 COC(=O)c1cc(NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc1N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D21 compound treatment 992006.0 129000.0 0.18 986061.0 161000.0 0.22 0.2883 0.9951 1205234 Maybridge1_004133 CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D22 compound treatment 933451.0 70600.0 0.1 878096.0 52700.0 0.07 0.123 0.9882 1525016 Maybridge1_004134 OC(CSc1ccc(F)cc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D23 compound treatment 972189.0 109000.0 0.16 929874.0 104000.0 0.15 0.213 0.9995 2071484 Maybridge1_004135 CCOC(=O)/C(=N/Nc1ccccc1)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 D24 compound treatment 156564.0 -706000.0 -1.0 145259.0 -680000.0 -0.95 -1.3809 -0.9996 2071485 Maybridge1_004136 CC(=O)c1ccc(OCC(O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E01 mock treatment 864843.0 2030.0 0.0 838760.0 13400.0 0.02 0.0152 0.807 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E02 mock treatment 881479.0 18700.0 0.03 879832.0 54400.0 0.08 0.0724 0.9009 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E03 compound treatment 961877.0 99100.0 0.14 963998.0 139000.0 0.19 0.2363 0.9879 1157986 Maybridge1_004137 CCN(CCS(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E04 compound treatment 934671.0 71900.0 0.1 934217.0 109000.0 0.15 0.1796 0.9815 2071486 Maybridge1_004138 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E05 compound treatment 908507.0 45700.0 0.06 979914.0 155000.0 0.22 0.1983 0.8811 1925341 Maybridge1_004139 Nc1cc(nn1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E06 compound treatment 927621.0 64800.0 0.09 982967.0 158000.0 0.22 0.2206 0.9256 2071487 Maybridge1_004140 Nc1ncnc(SCc2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E07 compound treatment 980463.0 118000.0 0.17 993475.0 168000.0 0.23 0.2841 0.9863 2071488 Maybridge1_004141 Cc1cc2[nH]c(C)cc(=O)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E08 compound treatment 1000020.0 137000.0 0.2 1007741.0 182000.0 0.25 0.3178 0.9914 2071489 Maybridge1_004142 CNC(=O)NNC(=O)c1cccnc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E09 compound treatment 972708.0 110000.0 0.16 1019617.0 194000.0 0.27 0.302 0.9658 1549660 Maybridge1_004143 CC1CCCCN1Cc2c(C)n(C)n(c3ccccc3)c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E10 compound treatment 941193.0 78400.0 0.11 957508.0 132000.0 0.18 0.2091 0.971 1568475 Maybridge1_004144 Cn1nc(O)cc1Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E11 compound treatment 979179.0 116000.0 0.17 1017823.0 192000.0 0.27 0.3068 0.973 2071490 Maybridge1_004145 CCc1ccc(NC(=S)Nc2cc(C)cc(C)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E12 compound treatment 953978.0 91200.0 0.13 1011935.0 187000.0 0.26 0.2756 0.9483 1731945 Maybridge1_004146 COc1cc(CCC(C)N)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E13 compound treatment 956710.0 93900.0 0.13 1019531.0 194000.0 0.27 0.2859 0.9469 2071491 Maybridge1_004147 OC(=O)C1C(C2CC1C=C2)C(=O)NNC(=O)CCc3ccc(O)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E14 compound treatment 939645.0 76800.0 0.11 1030279.0 205000.0 0.29 0.2793 0.913 43143 Maybridge1_004148 O[C@@H](C(=O)O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E15 compound treatment 989536.0 127000.0 0.18 1075132.0 250000.0 0.35 0.3737 0.953 2071492 Maybridge1_004149 COc1cc2CCC(=O)c2c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E16 compound treatment 970949.0 108000.0 0.15 1054307.0 229000.0 0.32 0.3345 0.9439 1022845 Maybridge1_004150 CC(=O)Nc1ncc(s1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E17 compound treatment 942350.0 79500.0 0.11 1037039.0 212000.0 0.3 0.2887 0.9133 2071493 Maybridge1_004151 CC(=O)c1ccc(Sc2ccccc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E18 compound treatment 947826.0 85000.0 0.12 1045688.0 220000.0 0.31 0.3027 0.9169 1503681 Maybridge1_004152 OC(CN1CCCC1)Cn2c3ccccc3c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E19 compound treatment 982927.0 120000.0 0.17 1015179.0 190000.0 0.26 0.3079 0.9775 1399804 Maybridge1_004153 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3c(C)onc3c4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E20 compound treatment 944433.0 81600.0 0.12 1006848.0 181000.0 0.25 0.261 0.9375 2071494 Maybridge1_004154 OC1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E21 compound treatment 940807.0 78000.0 0.11 1040761.0 215000.0 0.3 0.2908 0.9083 2071495 Maybridge1_004155 [O-][N+](=O)c1ccc(NC2OC(=O)c3ccccc23)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E22 compound treatment 951112.0 88300.0 0.13 963056.0 138000.0 0.19 0.2245 0.9788 1498806 Maybridge1_004156 Brc1ccc(cc1)C2NC(=O)Cc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E23 compound treatment 893237.0 30400.0 0.04 942175.0 117000.0 0.16 0.1457 0.8649 2071496 Maybridge1_004157 Nc1ccccc1SCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 E24 compound treatment 221985.0 -641000.0 -0.91 163887.0 -662000.0 -0.92 -1.2968 -1.0 1082377 Maybridge1_004158 CC1(O)C2CC3CC(C2)CC1C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F01 mock treatment 915467.0 52700.0 0.07 834441.0 9030.0 0.01 0.0619 0.8146 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F02 mock treatment 888176.0 25400.0 0.04 877425.0 52000.0 0.07 0.0768 0.948 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F03 compound treatment 970596.0 108000.0 0.15 952446.0 127000.0 0.18 0.2337 0.9974 1462680 Maybridge1_004159 CC(=O)Oc1cc(CO)cc(OC(=O)C)c1OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F04 compound treatment 902757.0 39900.0 0.06 937028.0 112000.0 0.16 0.1502 0.9066 1021543 Maybridge1_004160 Oc1cc(nc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F05 compound treatment 1025519.0 163000.0 0.23 951684.0 126000.0 0.18 0.2881 0.9909 2071497 Maybridge1_004161 O=C1c2cccc(Oc3ccccc3)c2C(=O)c4c(Oc5ccccc5)cccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F06 compound treatment 940058.0 77200.0 0.11 951487.0 126000.0 0.18 0.202 0.9743 2071498 Maybridge1_004162 CC(=O)OC[C@@H](OC(=O)C)C(O[C@@H]1O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F07 compound treatment 1043280.0 180000.0 0.26 1000641.0 175000.0 0.24 0.3543 0.9997 2071499 Maybridge1_004163 Clc1ccc(cc1)C(=O)O/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F08 compound treatment 1004796.0 142000.0 0.2 1004639.0 179000.0 0.25 0.3195 0.9944 2071500 Maybridge1_004164 CC(=O)O[C@H]1CO[C@@H](C#N)[C@H](OC(=O)C)[C@H]1OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F09 compound treatment 928281.0 65500.0 0.09 1007764.0 182000.0 0.25 0.2457 0.9071 1240231 Maybridge1_004165 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F10 compound treatment 935874.0 73100.0 0.1 963978.0 139000.0 0.19 0.2101 0.9576 2071501 Maybridge1_004166 Cc1ccc(cc1)/C(=C/2\C=C(\Br)/C(=N/O)/C=C2/Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F11 compound treatment 1011586.0 149000.0 0.21 991884.0 166000.0 0.23 0.3138 0.9989 1722183 Maybridge1_004167 C(N1CCOCC1)n2cnc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F12 compound treatment 907380.0 44600.0 0.06 985184.0 160000.0 0.22 0.2024 0.8736 2071502 Maybridge1_004168 Oc1c(Br)cc(Br)cc1/C=N/N=C\2/C(=O)Nc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F13 compound treatment 1009037.0 146000.0 0.21 1035305.0 210000.0 0.29 0.354 0.986 1075384 Maybridge1_004169 O=C1C(C#N)C(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F14 compound treatment 1001980.0 139000.0 0.2 1045868.0 220000.0 0.31 0.3574 0.9773 2071503 Maybridge1_004170 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4cccc(Cl)c4)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F15 compound treatment 1063762.0 201000.0 0.29 1030301.0 205000.0 0.29 0.4041 1.0 2071504 Maybridge1_004171 CCOC(=O)/C(=N/Nc1ccc(OC)cc1)/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F16 compound treatment 1000319.0 138000.0 0.2 1020642.0 195000.0 0.27 0.3308 0.9868 1030966 Maybridge1_004172 O=C(NCc1ccco1)Nc2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F17 compound treatment 993505.0 131000.0 0.19 1043991.0 219000.0 0.3 0.347 0.9718 2071505 Maybridge1_004173 CC1[C@@H]([C@H]1C(=O)NN)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F18 compound treatment 958781.0 96000.0 0.14 973581.0 148000.0 0.21 0.2426 0.9797 1204063 Maybridge1_004174 Cc1onc(c1C(=O)Nc2ccc3OCCOc3c2)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F19 compound treatment 993495.0 131000.0 0.19 1070424.0 245000.0 0.34 0.373 0.959 2071506 Maybridge1_004175 Cn1c2CCC/C(=N\OC(=O)c3cccc(c3)C(F)(F)F)/c2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F20 compound treatment 1002543.0 140000.0 0.2 987695.0 162000.0 0.23 0.3006 0.9979 2071507 Maybridge1_004176 Cc1c(sc2ccc(Cl)cc12)C(=O)CN3CCN(CC3)c4ccc(cn4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F21 compound treatment 1054054.0 191000.0 0.27 1018273.0 193000.0 0.27 0.3825 1.0 1019643 Maybridge1_004177 Clc1ccc2ocnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F22 compound treatment 948338.0 85500.0 0.12 909124.0 83700.0 0.12 0.1686 0.9998 2071508 Maybridge1_004178 Cc1cc(Cl)cc(Br)c1OCC(O)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F23 compound treatment 972600.0 110000.0 0.16 939188.0 114000.0 0.16 0.2226 1.0 1046573 Maybridge1_004179 CCOC(=O)C(=CNc1ccccc1Cl)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 F24 compound treatment 157926.0 -705000.0 -1.0 151555.0 -674000.0 -0.94 -1.3734 -0.9995 2071509 Maybridge1_004180 CC(=O)c1ccc(OCC(O)CN2CCC(CC2)C(=O)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G01 mock treatment 846912.0 -15900.0 -0.02 816194.0 -9210.0 -0.01 -0.0251 -0.9641 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G02 mock treatment 859096.0 -3720.0 -0.01 853395.0 28000.0 0.04 0.0239 0.6058 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G03 compound treatment 948656.0 85800.0 0.12 916666.0 91300.0 0.13 0.1763 0.9998 2071510 Maybridge1_004181 N/C(=C(\NCc1cccc(Cl)c1)/C#N)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G04 compound treatment 918446.0 55600.0 0.08 956104.0 131000.0 0.18 0.1848 0.9302 2071511 Maybridge1_004182 COc1cc(cc(OC)c1OC)C(=O)NNC(=O)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G05 compound treatment 954686.0 91900.0 0.13 955840.0 130000.0 0.18 0.221 0.9868 1083345 Maybridge1_004183 Cc1ccc(cc1)S(=O)(=O)C=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G06 compound treatment 909877.0 47100.0 0.07 928406.0 103000.0 0.14 0.1489 0.9396 2071512 Maybridge1_004184 Nc1ncnc(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G07 compound treatment 953206.0 90400.0 0.13 978267.0 153000.0 0.21 0.2416 0.9707 1456405 Maybridge1_004185 CCN(CCS(=O)(=O)c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G08 compound treatment 928254.0 65400.0 0.09 973817.0 148000.0 0.21 0.2122 0.9349 2071513 Maybridge1_004186 Cn1nc(O)cc1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G09 compound treatment 952332.0 89500.0 0.13 980720.0 155000.0 0.22 0.2432 0.9679 1143794 Maybridge1_004187 CC1CCCN(Cc2c(C)n(C)n(c3ccccc3)c2=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G10 compound treatment 924602.0 61800.0 0.09 977989.0 153000.0 0.21 0.2126 0.9234 2071514 Maybridge1_004188 CSc1nc(N)n(n1)c2c(Cl)cc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G11 compound treatment 935195.0 72400.0 0.1 971641.0 146000.0 0.2 0.217 0.9499 1296321 Maybridge1_004189 Cc1ccc(NC(=S)Nc2cc(C)cc(C)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G12 compound treatment 903121.0 40300.0 0.06 983568.0 158000.0 0.22 0.1965 0.8622 2071515 Maybridge1_004190 Cc1nn(c(O)c1C(=O)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G13 compound treatment 911363.0 48500.0 0.07 971485.0 146000.0 0.2 0.1929 0.8966 1087761 Maybridge1_004191 NNC(=O)c1ccccc1CO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G14 compound treatment 909090.0 46300.0 0.07 988999.0 164000.0 0.23 0.2079 0.8754 1005858 Maybridge1_004192 CC1=NN(C(=O)C1[N+](=O)[O-])c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G15 compound treatment 969380.0 107000.0 0.15 1027866.0 202000.0 0.28 0.3068 0.9574 2071516 Maybridge1_004193 Clc1ccc(cc1)C2=NN(C(C2)c3cccs3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G16 compound treatment 960574.0 97800.0 0.14 1023313.0 198000.0 0.28 0.2935 0.9496 1103751 Maybridge1_004194 OCC(NC(=O)c1ccccc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G17 compound treatment 1002521.0 140000.0 0.2 1139888.0 314000.0 0.44 0.4506 0.9359 1436971 Maybridge1_004195 Cc1ccc(cc1)S(=O)(=O)Nc2sc3CCCCc3c2C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G18 compound treatment 972424.0 110000.0 0.16 996017.0 171000.0 0.24 0.2785 0.979 1642807 Maybridge1_004196 COc1cc2CC(=O)NC(c3ccc(Cl)cc3)c2cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G19 compound treatment 2655289.0 1790000.0 2.55 2221856.0 1400000.0 1.95 3.1796 0.9912 2071517 Maybridge1_004197 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3c(O)ccc4ccccc34)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G20 compound treatment 885739.0 22900.0 0.03 974170.0 149000.0 0.21 0.1698 0.8083 1049679 Maybridge1_004198 CNc1ccc(cc1)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G21 compound treatment 862873.0 58.2 0.0 999635.0 174000.0 0.24 0.1719 0.7073 2071518 Maybridge1_004199 CCOC(=O)c1ccc(SCC(=O)Nc2c(C)cc(C)cc2C)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G22 compound treatment 920160.0 57300.0 0.08 934869.0 109000.0 0.15 0.1656 0.9569 1448022 Maybridge1_004200 Clc1ccc(cc1)C2NC(=O)Cc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G23 compound treatment 911346.0 48500.0 0.07 902630.0 77200.0 0.11 0.125 0.9769 2071519 Maybridge1_004201 [O-][N+](=O)c1cc(Cl)ccc1Sc2ccccc2NC3OC(=O)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 G24 compound treatment 157381.0 -705000.0 -1.0 170300.0 -655000.0 -0.91 -1.3554 -0.9989 2071520 Maybridge1_004202 CC(C)c1cccc(C(C)C)c1N=C=Nc2c(cccc2C(C)C)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H01 mock treatment 906886.0 44100.0 0.06 809095.0 -16300.0 -0.02 0.0282 0.4234 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H02 mock treatment 797851.0 -65000.0 -0.09 843134.0 17700.0 0.02 -0.0478 -0.5003 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H03 compound treatment 909508.0 46700.0 0.07 924929.0 99500.0 0.14 0.1451 0.943 1446039 Maybridge1_004203 CCN(CC)c1cccc(NC(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H04 compound treatment 877012.0 14200.0 0.02 905186.0 79800.0 0.11 0.093 0.822 2071521 Maybridge1_004204 O=C(CCN1C(=O)c2ccccc2C1=O)CCC(=O)CCN3C(=O)c4ccccc4C3=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H05 compound treatment 982957.0 120000.0 0.17 943934.0 119000.0 0.17 0.2377 0.9999 2071522 Maybridge1_004205 Cc1cc(C)c(N=C=Nc2c(C)cc(C)cc2C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H06 compound treatment 839074.0 -23700.0 -0.03 892164.0 66800.0 0.09 0.042 0.4237 2071523 Maybridge1_004206 NC(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H07 compound treatment 968338.0 106000.0 0.15 951723.0 126000.0 0.18 0.2307 0.9968 2071524 Maybridge1_004207 O=C(O/N=C/c1ccc2OCOc2c1)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H08 compound treatment 964731.0 102000.0 0.14 925159.0 99800.0 0.14 0.2009 0.9998 2071525 Maybridge1_004208 OC(C(O)C(=O)OCc1ccccc1)C(=O)OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H09 compound treatment 1013144.0 150000.0 0.21 989494.0 164000.0 0.23 0.313 0.9994 1356101 Maybridge1_004209 Clc1cccc(c1Cl)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H10 compound treatment 949653.0 86800.0 0.12 951506.0 126000.0 0.18 0.2117 0.985 2071526 Maybridge1_004210 O/N=C/C(=O)Nc1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H11 compound treatment 990265.0 127000.0 0.18 1000174.0 175000.0 0.24 0.3005 0.9894 1312285 Maybridge1_004211 C(N1CCCCC1)n2cnc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H12 compound treatment 923143.0 60300.0 0.09 944785.0 119000.0 0.17 0.1784 0.9525 1112784 Maybridge1_004212 ON=C1C=CC(=C(C#N)c2ccccc2)C=C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H13 compound treatment 1006061.0 143000.0 0.2 951901.0 126000.0 0.18 0.2688 0.9974 1055766 Maybridge1_004213 c1cc(oc1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H14 compound treatment 941137.0 78300.0 0.11 946989.0 122000.0 0.17 0.1987 0.9792 1533369 Maybridge1_004214 Clc1cccc(Oc2cccc(c2)S(=O)(=O)NCc3ccc4OCOc4c3)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H15 compound treatment 975322.0 113000.0 0.16 1021052.0 196000.0 0.27 0.3061 0.9676 2071527 Maybridge1_004215 CCOC(=O)/C(=N/Nc1ccc(Br)cc1)/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H16 compound treatment 983968.0 121000.0 0.17 978127.0 153000.0 0.21 0.2724 0.9945 1284097 Maybridge1_004216 O=C(NCc1ccco1)NC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H17 compound treatment 1002125.0 139000.0 0.2 1035873.0 210000.0 0.29 0.3476 0.9817 2071528 Maybridge1_004217 CC(C)(C)OC(=O)N1CCC(=O)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H18 compound treatment 950672.0 87900.0 0.12 982617.0 157000.0 0.22 0.2434 0.9644 2071529 Maybridge1_004218 FC(F)(F)c1oc(cc1C(=O)Nc2ccc3OCCOc3c2)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H19 compound treatment 997714.0 135000.0 0.19 987097.0 162000.0 0.23 0.2951 0.9968 2071530 Maybridge1_004219 Cn1c2CCC/C(=N\OC(=O)c3ccc(cc3)C(C)(C)C)/c2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H20 compound treatment 971915.0 109000.0 0.16 924760.0 99400.0 0.14 0.2077 0.9984 1178132 Maybridge1_004220 Fc1ccc(F)c(NC(=O)N2CCN(CC2)c3ccnc4cc(Cl)ccc34)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H21 compound treatment 979736.0 117000.0 0.17 981879.0 156000.0 0.22 0.2719 0.991 2071531 Maybridge1_004221 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Oc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H22 compound treatment 939096.0 76300.0 0.11 927106.0 102000.0 0.14 0.177 0.9912 2071532 Maybridge1_004222 Oc1ccc(cc1)n2nnnc2SCc3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H23 compound treatment 962845.0 100000.0 0.14 951657.0 126000.0 0.18 0.2251 0.9944 1580966 Maybridge1_004223 COc1ccccc1N2CCN(Cc3ccc(F)cc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 H24 compound treatment 164244.0 -699000.0 -0.99 132361.0 -693000.0 -0.97 -1.3859 -0.9999 2071533 Maybridge1_004224 CC(=O)c1ccc(OCC(O)CN2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I01 mock treatment 849751.0 -13100.0 -0.02 836523.0 11100.0 0.02 -0.0022 -0.0898 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I02 mock treatment 902917.0 40100.0 0.06 862480.0 37100.0 0.05 0.0769 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I03 compound treatment 931307.0 68500.0 0.1 926775.0 101000.0 0.14 0.1688 0.9835 2071534 Maybridge1_004225 NC(=O)c1nnc2cc(nn2c1c3ccccc3Cl)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I04 compound treatment 958982.0 96200.0 0.14 919731.0 94300.0 0.13 0.1897 0.9998 2071535 Maybridge1_004226 Cc1onc(c1C(=O)NNC(=O)c2c(C)onc2c3ccccc3Cl)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I05 compound treatment 990346.0 128000.0 0.18 957526.0 132000.0 0.18 0.2585 1.0 2071536 Maybridge1_004227 Cc1cc(NC(=O)C(Cl)(Cl)Cl)n(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I06 compound treatment 923038.0 60200.0 0.09 906137.0 80700.0 0.11 0.1402 0.9909 1731523 Maybridge1_004228 CC(C)(C)c1ccc(OC(C)(C)C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I07 compound treatment 926953.0 64100.0 0.09 926775.0 101000.0 0.14 0.1645 0.9775 2071537 Maybridge1_004229 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I08 compound treatment 916753.0 53900.0 0.08 970724.0 145000.0 0.2 0.1976 0.9116 1664186 Maybridge1_004230 Clc1ccc(cc1)c2n[nH]c(=S)[nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I09 compound treatment 971426.0 109000.0 0.15 997817.0 172000.0 0.24 0.2792 0.9771 1328726 Maybridge1_004231 Cc1nn(C)c(NC(=O)c2ccccc2Cl)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I10 compound treatment 935312.0 72500.0 0.1 979715.0 154000.0 0.22 0.2251 0.9432 2071538 Maybridge1_004232 CSc1nc(N)n(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I11 compound treatment 952059.0 89200.0 0.13 984019.0 159000.0 0.22 0.2462 0.9652 2071539 Maybridge1_004233 Cc1cc(C)cc(NC(=S)Nc2cccc(Cl)c2C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I12 compound treatment 945330.0 82500.0 0.12 982867.0 157000.0 0.22 0.2383 0.9569 1056014 Maybridge1_004234 OCc1ccccc1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I13 compound treatment 1001690.0 139000.0 0.2 1001669.0 176000.0 0.25 0.3135 0.9941 2071540 Maybridge1_004235 Clc1ccc(NC(=O)C(=O)NCc2ccncc2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I14 compound treatment 963863.0 101000.0 0.14 1007007.0 182000.0 0.25 0.2807 0.9639 2071541 Maybridge1_004236 CC1(C)COC2(CCC(=O)CC2)OC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I15 compound treatment 954261.0 91400.0 0.13 1056534.0 231000.0 0.32 0.3199 0.9203 1261522 Maybridge1_004237 Cc1cccnc1NC2OC(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I16 compound treatment 922728.0 59900.0 0.09 981011.0 156000.0 0.22 0.2137 0.9166 1531996 Maybridge1_004238 COC(=O)C(Cc1cccc(C)n1)(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I17 compound treatment 976034.0 113000.0 0.16 1054159.0 229000.0 0.32 0.3394 0.9499 2071542 Maybridge1_004239 CC(=O)c1ccc(Sc2ccccn2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I18 compound treatment 954969.0 92200.0 0.13 997590.0 172000.0 0.24 0.2625 0.9594 1118153 Maybridge1_004240 Cc1c(sc(N)c1C(=O)N)C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I19 compound treatment 986412.0 124000.0 0.18 993444.0 168000.0 0.23 0.29 0.9899 2071543 Maybridge1_004241 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Br)ccc3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I20 compound treatment 959648.0 96800.0 0.14 985697.0 160000.0 0.22 0.2555 0.9729 1231395 Maybridge1_004242 O=C(Cc1ccccc1)Nc2ccc3ccccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I21 compound treatment 995349.0 133000.0 0.19 991711.0 166000.0 0.23 0.2973 0.9947 2071544 Maybridge1_004243 COc1cc([N+](=O)[O-])c(OC)cc1SCC(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I22 compound treatment 931370.0 68600.0 0.1 962289.0 137000.0 0.19 0.2039 0.9513 1627134 Maybridge1_004244 Nc1nc(cs1)c2ccc-3c(Cc4ccccc43)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I23 compound treatment 933892.0 71100.0 0.1 949522.0 124000.0 0.17 0.1939 0.9672 1549155 Maybridge1_004245 Cc1c(C)c(C)c(CSc2ccccc2NC3OC(=O)c4ccccc34)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 I24 compound treatment 142461.0 -720000.0 -1.02 157014.0 -668000.0 -0.93 -1.3835 -0.9989 2071545 Maybridge1_004246 COC(=O)C(COS(=O)(=O)c1ccc(C)cc1)NC(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J01 mock treatment 906470.0 43700.0 0.06 817410.0 -8000.0 -0.01 0.036 0.5709 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J02 mock treatment 904797.0 42000.0 0.06 868421.0 43000.0 0.06 0.0846 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J03 compound treatment 947520.0 84700.0 0.12 906120.0 80700.0 0.11 0.1648 0.9994 2071546 Maybridge1_004247 C(C1=N[C@@H]([C@@H](O1)c2ccccc2)c3ccccc3)C4=N[C@@H]([C@@H](O4)c5ccccc5)c6ccccc6 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J04 compound treatment 545696.0 -317000.0 -0.45 587318.0 -238000.0 -0.33 -0.5537 -0.9887 2071547 Maybridge1_004248 OC[C@H]1O[C@H](O)[C@H](NNc2ccccc2)[C@@H](O)[C@@H]1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J05 compound treatment 965009.0 102000.0 0.15 935287.0 110000.0 0.15 0.2111 0.9996 1069755 Maybridge1_004249 COc1cc(OC)c(OC)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J06 compound treatment 974811.0 112000.0 0.16 878167.0 52800.0 0.07 0.1647 0.9385 2071548 Maybridge1_004250 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J07 compound treatment 979189.0 116000.0 0.17 931793.0 106000.0 0.15 0.2219 0.9985 2071549 Maybridge1_004251 Clc1ccc(C(=O)O/N=C/c2ccc3OCOc3c2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J08 compound treatment 982258.0 119000.0 0.17 895515.0 70100.0 0.1 0.1892 0.9656 2071550 Maybridge1_004252 CCSC(SCC)[C@H](O)[C@@H](O)[C@@H](O)CO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J09 compound treatment 1018166.0 155000.0 0.22 981887.0 156000.0 0.22 0.3105 1.0 1215373 Maybridge1_004253 Cc1ccc(cc1)C(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J10 compound treatment 937730.0 74900.0 0.11 961944.0 137000.0 0.19 0.21 0.9623 2071551 Maybridge1_004254 Cc1ccc(CSc2ssc(=S)c2c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J11 compound treatment 981528.0 119000.0 0.17 969546.0 144000.0 0.2 0.2615 0.9962 2071552 Maybridge1_004255 COC(=O)C1(C)CCC(C(=O)O)C1(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J12 compound treatment 961329.0 98500.0 0.14 929265.0 104000.0 0.14 0.2015 0.9999 2071553 Maybridge1_004256 Oc1ccc(Br)cc1/C=N/N2C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J13 compound treatment 1026205.0 163000.0 0.23 965588.0 140000.0 0.2 0.3025 0.9963 1396701 Maybridge1_004257 COc1ccc(CCNC(=O)c2ccc(Cl)cc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J14 compound treatment 826541.0 -36300.0 -0.05 971563.0 146000.0 0.2 0.1077 0.512 1397018 Maybridge1_004258 Fc1ccc(cc1Cl)S(=O)(=O)NCc2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J15 compound treatment 992322.0 130000.0 0.18 997695.0 172000.0 0.24 0.3001 0.9914 2071554 Maybridge1_004259 CCOC(=O)/C(=N/Nc1cccc(c1)[N+](=O)[O-])/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J16 compound treatment 1217607.0 355000.0 0.5 1006428.0 181000.0 0.25 0.5353 0.9488 2071555 Maybridge1_004260 CCOC(=O)C(C#N)C1C(=C(N)Oc2c(OC)cc(Br)cc12)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J17 compound treatment 993936.0 131000.0 0.19 998715.0 173000.0 0.24 0.3028 0.9918 2071556 Maybridge1_004261 Cn1c2CCC/C(=N\OC(=O)c3cccc4ccccc34)/c2c5ccccc15 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J18 compound treatment 976486.0 114000.0 0.16 965463.0 140000.0 0.2 0.2524 0.9956 1598126 Maybridge1_004262 COC(=O)c1ccc(n1C)S(=O)(=O)NCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J19 compound treatment 1006451.0 144000.0 0.2 999099.0 174000.0 0.24 0.3157 0.9964 1546260 Maybridge1_004263 CC1(C)C(NC(=O)c2c(Cl)cccc2Cl)[C@]3(C)CCC1C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J20 compound treatment 967097.0 104000.0 0.15 963864.0 138000.0 0.19 0.2414 0.9915 1367531 Maybridge1_004264 Clc1ccc2nc(sc2c1)N3CCN(CC3)S(=O)(=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J21 compound treatment 994130.0 131000.0 0.19 964623.0 139000.0 0.19 0.2693 0.9998 1298924 Maybridge1_004265 CC1(C)C2CCC1(C)C(C2)N3CCN(Cc4ccccc4)CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J22 compound treatment 941064.0 78200.0 0.11 901762.0 76400.0 0.11 0.154 0.9998 2071557 Maybridge1_004266 Oc1ccc(cc1)n2nnnc2SCc3cc(F)cc(F)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J23 compound treatment 907960.0 45100.0 0.06 932207.0 107000.0 0.15 0.1507 0.9292 2071558 Maybridge1_004267 Fc1ccc(cc1)C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 J24 compound treatment 159089.0 -704000.0 -1.0 140638.0 -685000.0 -0.96 -1.383 -0.9997 2071559 Maybridge1_004268 Oc1ccc(cc1)n2nnnc2SCC(=O)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K01 mock treatment 846785.0 -16000.0 -0.02 823144.0 -2260.0 0.0 -0.0184 -0.7974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K02 mock treatment 875661.0 12800.0 0.02 863189.0 37800.0 0.05 0.0502 0.8997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K03 compound treatment 923028.0 60200.0 0.09 905432.0 80000.0 0.11 0.1395 0.9914 2071560 Maybridge1_004269 CCOC(=O)/C(=N/Nc1cc(n[nH]1)c2ccccc2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K04 compound treatment 920458.0 57600.0 0.08 896206.0 70800.0 0.1 0.1278 0.9957 2071561 Maybridge1_004270 Cc1nc(COc2ccc(cc2)/C(=N/O)/N)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K05 compound treatment 959371.0 96600.0 0.14 913943.0 88500.0 0.12 0.1844 0.9986 1493954 Maybridge1_004271 Cc1cc(=O)n2nc(cc2[nH]1)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K06 compound treatment 917765.0 55000.0 0.08 867845.0 42400.0 0.06 0.0971 0.9906 1671220 Maybridge1_004272 CC(C)(Oc1ccc2ccccc2c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K07 compound treatment 942535.0 79700.0 0.11 910503.0 85100.0 0.12 0.1641 0.9997 1588381 Maybridge1_004273 Clc1ccc(cc1)S(=O)(=O)CCN2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K08 compound treatment 937948.0 75100.0 0.11 900610.0 75200.0 0.1 0.1497 1.0 2071562 Maybridge1_004274 CSc1nc(O)nc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K09 compound treatment 965482.0 103000.0 0.15 976842.0 151000.0 0.21 0.2526 0.9837 2071563 Maybridge1_004275 CCOc1cc(/C=N/C(=C(\N)/C#N)/C#N)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K10 compound treatment 922340.0 59500.0 0.08 933251.0 108000.0 0.15 0.1662 0.963 1542810 Maybridge1_004276 CCc1nc(O)cc2cc(OC)c(OC)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K11 compound treatment 955604.0 92800.0 0.13 947994.0 123000.0 0.17 0.2142 0.9918 2071564 Maybridge1_004277 OCc1ccccc1C(=O)N/N=C/c2ccc(O)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K12 compound treatment 899762.0 36900.0 0.05 920511.0 95100.0 0.13 0.1309 0.9178 2071565 Maybridge1_004278 Brc1ccc(cc1)C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K13 compound treatment 890518.0 27700.0 0.04 906596.0 81200.0 0.11 0.1079 0.9002 2071566 Maybridge1_004279 [O-][N+](=O)c1ccc(cc1)C(=O)c2ccc3CCCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K14 compound treatment 935015.0 72200.0 0.1 960622.0 135000.0 0.19 0.206 0.9591 2071567 Maybridge1_004280 OC1(Cc2ccccc2C3=NCCN31)c4ccc(F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K15 compound treatment 934588.0 71800.0 0.1 1003845.0 178000.0 0.25 0.2481 0.9225 2071568 Maybridge1_004281 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2SCCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K16 compound treatment 913890.0 51100.0 0.07 965397.0 140000.0 0.2 0.1894 0.9093 2071569 Maybridge1_004282 C1CN(CCN1)c2ncccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K17 compound treatment 938202.0 75400.0 0.11 971115.0 146000.0 0.2 0.2195 0.9553 2071570 Maybridge1_004283 CC(=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K18 compound treatment 943511.0 80700.0 0.11 951731.0 126000.0 0.18 0.2057 0.9784 2071571 Maybridge1_004284 Oc1ccccc1/C=N/CC\N=C\c2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K19 compound treatment 972356.0 110000.0 0.16 1003042.0 178000.0 0.25 0.2853 0.975 2071572 Maybridge1_004285 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Cl)ccc3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K20 compound treatment 913234.0 50400.0 0.07 936330.0 111000.0 0.15 0.1601 0.9389 2071573 Maybridge1_004286 Cc1ccc(cc1C)C(=O)c2c(C)ccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K21 compound treatment 973759.0 111000.0 0.16 989130.0 164000.0 0.23 0.273 0.9837 2071574 Maybridge1_004287 CCOC(=O)CSc1cc(OC)c(cc1OC)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K22 compound treatment 923716.0 60900.0 0.09 948014.0 123000.0 0.17 0.1822 0.9503 2071575 Maybridge1_004288 CCCCSc1nnc(S)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K23 compound treatment 950391.0 87600.0 0.12 920494.0 95100.0 0.13 0.1818 0.9995 2071576 Maybridge1_004289 CC(=O)c1ccc(Sc2ccccc2N)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 K24 compound treatment 165218.0 -698000.0 -0.99 149649.0 -676000.0 -0.94 -1.3679 -0.9997 2071577 Maybridge1_004290 CCC(C)C(NC(=O)OCC1c2ccccc2-c3ccccc13)C(=O)NC(C(C)C)C(=O)NC(CCCCNC(=O)OC(C)(C)C)C(=O)NC(CCC(=O)OC(C)(C)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L01 mock treatment 868165.0 5350.0 0.01 827412.0 2000.0 0.0 0.0074 0.9076 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L02 mock treatment 852444.0 -10400.0 -0.01 848521.0 23100.0 0.03 0.0124 0.3488 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L03 compound treatment 852648.0 -10200.0 -0.01 881431.0 56000.0 0.08 0.045 0.5666 2071578 Maybridge1_004291 Cc1ccc(cc1)S(=O)(=O)OCC(NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L04 compound treatment 910692.0 47900.0 0.07 884004.0 58600.0 0.08 0.1059 0.9959 1026962 Maybridge1_004292 COc1cc(cc(OC)c1OC)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L05 compound treatment 966497.0 104000.0 0.15 915460.0 90100.0 0.13 0.1931 0.9968 2071579 Maybridge1_004293 O=C(O/N=C/c1ccc2OCOc2c1)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L06 compound treatment 827263.0 -35600.0 -0.05 883325.0 57900.0 0.08 0.0214 0.2242 2071580 Maybridge1_004294 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@@H]2O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L07 compound treatment 964180.0 101000.0 0.14 945450.0 120000.0 0.17 0.2203 0.9972 2071581 Maybridge1_004295 O=C(O/N=C/c1ccc2OCOc2c1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L08 compound treatment 940175.0 77400.0 0.11 929255.0 104000.0 0.14 0.1802 0.9908 2071582 Maybridge1_004296 CCSC(SCC)[C@H](O)[C@@H](O)[C@H](O)CO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L09 compound treatment 938731.0 75900.0 0.11 958305.0 133000.0 0.19 0.2074 0.9669 1408083 Maybridge1_004297 Clc1ccc(C(=O)N2CCC(CC2)NC(=O)C3CCCCC3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L10 compound treatment 917973.0 55200.0 0.08 838965.0 13600.0 0.02 0.0688 0.8531 2071583 Maybridge1_004298 Cc1ccc(cc1)/C(=C/2\C=C(\Cl)/C(=N/O)/C=C2/Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L11 compound treatment 970635.0 108000.0 0.15 944470.0 119000.0 0.17 0.2258 0.9992 2071584 Maybridge1_004299 COC(=O)C1CCC(C)(C(=O)O)C1(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L12 compound treatment 918149.0 55300.0 0.08 912430.0 87000.0 0.12 0.1415 0.978 1570985 Maybridge1_004300 CC(=O)Nc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L13 compound treatment 979807.0 117000.0 0.17 963853.0 138000.0 0.19 0.2542 0.9972 1533685 Maybridge1_004301 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L14 compound treatment 901512.0 38700.0 0.06 924805.0 99400.0 0.14 0.1369 0.9181 2071585 Maybridge1_004302 Cn1c(Sc2nc3ccc(Cl)cc3s2)nnc1c4ccc(Cl)cc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L15 compound treatment 994068.0 131000.0 0.19 991821.0 166000.0 0.23 0.2961 0.9942 1713236 Maybridge1_004303 CC(=O)NCc1ccc(cc1)S(=O)(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L16 compound treatment 939115.0 76300.0 0.11 950635.0 125000.0 0.17 0.2002 0.9738 1467188 Maybridge1_004304 CCOC(=O)c1cc(NC(=O)Nc2ccc(C)c(Cl)c2)ccc1N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L17 compound treatment 974505.0 112000.0 0.16 983067.0 158000.0 0.22 0.2678 0.9873 2071586 Maybridge1_004305 FC(F)(F)c1cccc(c1)C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L18 compound treatment 965212.0 102000.0 0.15 940917.0 116000.0 0.16 0.2169 0.9987 1376744 Maybridge1_004306 Cc1cc(C)c(C#N)c(OCC(=O)Nc2ccc(Oc3ccccc3)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L19 compound treatment 977108.0 114000.0 0.16 954159.0 129000.0 0.18 0.2419 0.9988 1402584 Maybridge1_004307 CC1(C)C(NC(=O)c2ccc(Cl)cc2Cl)[C@]3(C)CCC1C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L20 compound treatment 953988.0 91200.0 0.13 941688.0 116000.0 0.16 0.2064 0.9938 1196364 Maybridge1_004308 OC(=O)C1CCC1C(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L21 compound treatment 1023822.0 161000.0 0.23 943917.0 119000.0 0.17 0.2788 0.9872 2071587 Maybridge1_004309 COc1ccc(CC2CCC(=O)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L22 compound treatment 969963.0 107000.0 0.15 914358.0 89000.0 0.12 0.1955 0.9948 2071588 Maybridge1_004310 COC(=O)Cc1nc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)sc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L23 compound treatment 986824.0 124000.0 0.18 920539.0 95100.0 0.13 0.2185 0.9902 1044240 Maybridge1_004311 Brc1ccc2[nH]c3ccccc3c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 L24 compound treatment 159686.0 -703000.0 -1.0 131994.0 -693000.0 -0.97 -1.3909 -0.9999 1291967 Maybridge1_004312 OC(COc1ccc(F)cc1)CN2CCN(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M01 mock treatment 857838.0 -4980.0 -0.01 810603.0 -14800.0 -0.02 -0.0196 -0.8982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M02 mock treatment 828200.0 -34600.0 -0.05 871211.0 45800.0 0.06 0.0104 0.1285 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M03 compound treatment 946674.0 83900.0 0.12 938586.0 113000.0 0.16 0.1959 0.9904 1140868 Maybridge1_004313 Nc1cc(nn1c2ccccc2)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M04 compound treatment 868203.0 5390.0 0.01 859249.0 33800.0 0.05 0.0388 0.8113 1497141 Maybridge1_004314 Cc1c(Cl)c(O)nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M05 compound treatment 843914.0 -18900.0 -0.03 926696.0 101000.0 0.14 0.0809 0.5625 2071589 Maybridge1_004315 FC(F)(F)c1cc(=O)n([nH]1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M06 compound treatment 893974.0 31200.0 0.04 869807.0 44400.0 0.06 0.0751 0.9865 2071590 Maybridge1_004316 CC1(C)N=C(N)N=C(N)N1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M07 compound treatment 955631.0 92800.0 0.13 934507.0 109000.0 0.15 0.2009 0.9975 1701903 Maybridge1_004317 Clc1ccc(cc1)S(=O)(=O)CCN2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M08 compound treatment 899678.0 36900.0 0.05 893973.0 68600.0 0.1 0.1047 0.96 1496378 Maybridge1_004318 Clc1ccc(cc1)c2nc(=O)[nH]c(=S)[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M09 compound treatment 931253.0 68400.0 0.1 922384.0 97000.0 0.14 0.1645 0.987 1369556 Maybridge1_004319 Cc1nn(C)c(NC(=O)c2ccc(Cl)cc2Cl)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M10 compound treatment 867026.0 4210.0 0.01 870442.0 45000.0 0.06 0.0486 0.771 1006055 Maybridge1_004320 CCCCCCCCCCCCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M11 compound treatment 974260.0 111000.0 0.16 951188.0 126000.0 0.18 0.2361 0.9987 2071591 Maybridge1_004321 OCc1ccccc1C(=O)N/N=C/c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M12 compound treatment 930813.0 68000.0 0.1 922710.0 97300.0 0.14 0.1643 0.9862 1049047 Maybridge1_004322 [O-][N+](=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M13 compound treatment 946303.0 83500.0 0.12 964152.0 139000.0 0.19 0.2208 0.9725 2071592 Maybridge1_004323 Cc1onc(c1C(=O)N2CCC(CCCC3CCN(CC3)C(=O)c4c(C)onc4c5c(Cl)cccc5Cl)CC2)c6c(Cl)cccc6Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M14 compound treatment 914826.0 52000.0 0.07 967175.0 142000.0 0.2 0.1921 0.91 2071593 Maybridge1_004324 CCC[C@H]1[C@@H](Cc2cncn2C)COC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M15 compound treatment 946108.0 83300.0 0.12 969641.0 144000.0 0.2 0.226 0.9681 2071594 Maybridge1_004325 Clc1c(sc2ccccc12)C(=O)Nc3ccccc3SCCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M16 compound treatment 911173.0 48400.0 0.07 950008.0 125000.0 0.17 0.1715 0.9177 2071595 Maybridge1_004326 N[C@@H](C(=O)O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M17 compound treatment 968320.0 106000.0 0.15 979617.0 154000.0 0.22 0.2582 0.9845 1313557 Maybridge1_004327 CCOC(=O)c1ccc(N2CCCCC2)c(NS(=O)(=O)c3cc(Cl)c(Cl)cc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M18 compound treatment 947984.0 85200.0 0.12 932692.0 107000.0 0.15 0.1914 0.9945 1011577 Maybridge1_004328 Cc1ccc2cc(C)c(C)cc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M19 compound treatment 989453.0 127000.0 0.18 1026500.0 201000.0 0.28 0.3257 0.9771 2071596 Maybridge1_004329 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Br)cc(Br)c3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M20 compound treatment 924478.0 61700.0 0.09 926153.0 101000.0 0.14 0.1614 0.9742 1686247 Maybridge1_004330 CC(=O)Oc1cc(OC(=O)C)cc(c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M21 compound treatment 887972.0 25200.0 0.04 957668.0 132000.0 0.18 0.1557 0.8288 2071597 Maybridge1_004331 [O-][N+](=O)c1cc(Cl)c(Sc2ccccc2)cc1Sc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M22 compound treatment 925505.0 62700.0 0.09 904456.0 79000.0 0.11 0.141 0.9944 2071598 Maybridge1_004332 Sc1nc(c([nH]1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M23 compound treatment 957507.0 94700.0 0.13 919811.0 94400.0 0.13 0.1883 0.9999 2071599 Maybridge1_004333 Nc1ccccc1SCc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 M24 compound treatment 730921.0 -132000.0 -0.19 590356.0 -235000.0 -0.33 -0.3644 -0.9649 2071600 Maybridge1_004334 CCCCCCSc1nnc(S)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N01 mock treatment 873023.0 10200.0 0.01 832161.0 6750.0 0.01 0.0169 0.9781 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N02 mock treatment 900358.0 37500.0 0.05 865999.0 40600.0 0.06 0.0778 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N03 compound treatment 952135.0 89300.0 0.13 915207.0 89800.0 0.13 0.1784 1.0 2071601 Maybridge1_004335 COC(=O)C(NC(=O)OCc1ccccc1)C(C)OS(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N04 compound treatment 934805.0 72000.0 0.1 892667.0 67300.0 0.09 0.1387 0.999 931 Maybridge1_004336 NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N05 compound treatment 929120.0 66300.0 0.09 899142.0 73700.0 0.1 0.1394 0.9991 2071602 Maybridge1_004337 COc1ccccc1CC(=O)O/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N06 compound treatment 925602.0 62800.0 0.09 852700.0 27300.0 0.04 0.0901 0.9278 2071603 Maybridge1_004338 CC(=O)OC[C@H]1O[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1O[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N07 compound treatment 982707.0 120000.0 0.17 931586.0 106000.0 0.15 0.2253 0.9975 1654475 Maybridge1_004339 Cc1ccc(cc1)C(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N08 compound treatment 935439.0 72600.0 0.1 889321.0 63900.0 0.09 0.1361 0.9973 2071604 Maybridge1_004340 COCC1(C)OC(=O)C(=C1C)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N09 compound treatment 980521.0 118000.0 0.17 912370.0 87000.0 0.12 0.2041 0.9875 1437551 Maybridge1_004341 O=C(NC1CCN(CC1)C(=O)c2ccco2)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N10 compound treatment 873481.0 10700.0 0.02 833202.0 7790.0 0.01 0.0184 0.9867 2071605 Maybridge1_004342 Cc1ccc(cc1)/C(=C/2\C=C/C(=N\O)/C(=C2/Cl)/Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N11 compound treatment 972571.0 110000.0 0.16 919486.0 94100.0 0.13 0.2031 0.9963 2071606 Maybridge1_004343 CC(C)(C)c1cc(n[nH]1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N12 compound treatment 931020.0 68200.0 0.1 950139.0 125000.0 0.17 0.1916 0.9619 1478375 Maybridge1_004344 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3c(C)onc3c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N13 compound treatment 921636.0 58800.0 0.08 971907.0 146000.0 0.2 0.2036 0.9223 1075430 Maybridge1_004345 OCC(NC(=O)C(Cl)Cl)C(O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N14 compound treatment 896121.0 33300.0 0.05 920581.0 95200.0 0.13 0.1274 0.9036 2071607 Maybridge1_004346 Cn1c(Sc2nc3ccc(Cl)cc3s2)nnc1c4ccc5ncccc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N15 compound treatment 1018348.0 156000.0 0.22 939215.0 114000.0 0.16 0.2686 0.9868 1510250 Maybridge1_004347 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N16 compound treatment 945071.0 82300.0 0.12 930706.0 105000.0 0.15 0.1866 0.9936 2071608 Maybridge1_004348 COCc1cc(O)nc(SC2CC(=O)N(C2=O)c3ccc(cc3)N4CCOCC4)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N17 compound treatment 1008743.0 146000.0 0.21 984120.0 159000.0 0.22 0.3033 0.9995 2071609 Maybridge1_004349 Cn1c2CCC/C(=N\OC(=O)c3ccc(Cl)cc3)/c2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N18 compound treatment 966488.0 104000.0 0.15 930472.0 105000.0 0.15 0.2079 1.0 1382314 Maybridge1_004350 Cc1nnsc1C(=O)NCc2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N19 compound treatment 972728.0 110000.0 0.16 950916.0 126000.0 0.18 0.2343 0.9984 1354484 Maybridge1_004351 CC1(C)C(NS(=O)(=O)c2ccc(Cl)cc2)[C@]3(C)CCC1C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N20 compound treatment 950251.0 87400.0 0.12 912337.0 86900.0 0.12 0.1737 0.9999 1437585 Maybridge1_004352 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N21 compound treatment 952266.0 89500.0 0.13 975992.0 151000.0 0.21 0.2385 0.9711 2071610 Maybridge1_004353 Brc1cnc(nc1)N2CCN(CC2)C(c3ccccc3)(c4ccccc4)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N22 compound treatment 964652.0 102000.0 0.14 934997.0 110000.0 0.15 0.2105 0.9996 2071611 Maybridge1_004354 COC(=O)Cc1nc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)sc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N23 compound treatment 980999.0 118000.0 0.17 943261.0 118000.0 0.16 0.2351 0.9999 1983514 Maybridge1_004355 O/N=C/C(=O)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 N24 compound treatment 598780.0 -264000.0 -0.38 613207.0 -212000.0 -0.3 -0.4748 -0.9931 2071612 Maybridge1_004356 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3nc(no3)c4ccc(cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O01 mock treatment 868984.0 6170.0 0.01 786061.0 -39300.0 -0.05 -0.0326 -0.5866 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O02 mock treatment 809394.0 -53400.0 -0.08 803834.0 -21600.0 -0.03 -0.075 -0.9178 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O03 compound treatment 907807.0 45000.0 0.06 888102.0 62700.0 0.09 0.1071 0.9882 1044275 Maybridge1_004357 CS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O04 compound treatment 867859.0 5040.0 0.01 835835.0 10400.0 0.01 0.0154 0.9469 2071613 Maybridge1_004358 CCCc1cc(O)nc(SCc2ccc(Cl)cc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O05 compound treatment 882751.0 19900.0 0.03 876263.0 50900.0 0.07 0.0702 0.919 1596267 Maybridge1_004359 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O06 compound treatment 861702.0 -1110.0 0.0 833828.0 8420.0 0.01 0.0072 0.6063 1044282 Maybridge1_004360 Clc1ccc(NC(=N)NC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O07 compound treatment 926677.0 63900.0 0.09 893857.0 68400.0 0.1 0.1317 0.9997 2071614 Maybridge1_004361 Nc1cc(n[nH]1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O08 compound treatment 912354.0 49500.0 0.07 856763.0 31400.0 0.04 0.0807 0.9737 2071615 Maybridge1_004362 CSc1nc(O)nc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O09 compound treatment 931462.0 68600.0 0.1 897621.0 72200.0 0.1 0.1402 0.9999 2071616 Maybridge1_004363 Cc1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)n(C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O10 compound treatment 824733.0 -38100.0 -0.05 842361.0 17000.0 0.02 -0.0216 -0.3651 2071617 Maybridge1_004364 COC(=O)c1c(N)cccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O11 compound treatment 895076.0 32300.0 0.05 883438.0 58000.0 0.08 0.0897 0.9638 2071618 Maybridge1_004365 OCc1ccccc1C(=O)N/N=C/C=C/c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O12 compound treatment 876326.0 13500.0 0.02 869367.0 44000.0 0.06 0.0569 0.8862 2071619 Maybridge1_004366 Oc1ccccc1/C=N/CC2CCC(C\N=C\c3ccccc3O)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O13 compound treatment 955933.0 93100.0 0.13 902530.0 77100.0 0.11 0.1697 0.9947 2071620 Maybridge1_004367 CC(C)N(CCC#N)C(=S)Nc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O14 compound treatment 872321.0 9510.0 0.01 868250.0 42800.0 0.06 0.0518 0.8457 1340247 Maybridge1_004368 Cc1nc2ccccc2c(C(=O)O)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O15 compound treatment 922393.0 59600.0 0.08 912862.0 87500.0 0.12 0.1462 0.9841 2071621 Maybridge1_004369 COc1cccc(/C=N/c2ccccc2SCCC#N)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O16 compound treatment 900517.0 37700.0 0.05 901669.0 76300.0 0.11 0.1131 0.9497 1015426 Maybridge1_004370 Cc1ccc(NC(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O17 compound treatment 957565.0 94800.0 0.13 969885.0 144000.0 0.2 0.2378 0.9809 1558027 Maybridge1_004371 CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)c3ccc(Cl)c(Cl)c3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O18 compound treatment 900257.0 37400.0 0.05 869148.0 43700.0 0.06 0.0808 0.9977 2071622 Maybridge1_004372 Cc1ccc(C#Cc2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O19 compound treatment 985626.0 123000.0 0.17 969935.0 145000.0 0.2 0.266 0.9974 2071623 Maybridge1_004373 CCOC(=O)c1ccc(N2CCOCC2)c(/N=C/c3cc(Cl)cc(Cl)c3O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O20 compound treatment 900728.0 37900.0 0.05 892808.0 67400.0 0.09 0.1046 0.9652 2071624 Maybridge1_004374 CC(OCc1ccccc1)C(NC(=O)OC(C)(C)C)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O21 compound treatment 959049.0 96200.0 0.14 890511.0 65100.0 0.09 0.161 0.9801 2071625 Maybridge1_004375 Nc1ccccc1Sc2cc(Sc3ccccc3N)c(cc2Cl)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O22 compound treatment 904779.0 42000.0 0.06 888209.0 62800.0 0.09 0.1041 0.9825 2071626 Maybridge1_004376 CCCSc1nnc(S)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O23 compound treatment 923514.0 60700.0 0.09 885366.0 60000.0 0.08 0.1202 0.9999 1022261 Maybridge1_004377 Nc1ccccc1Sc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 O24 compound treatment 512817.0 -350000.0 -0.5 517719.0 -308000.0 -0.43 -0.6554 -0.9973 1577497 Maybridge1_004378 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P01 mock treatment 913924.0 51100.0 0.07 786413.0 -39000.0 -0.05 0.0129 0.1425 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P02 mock treatment 873047.0 10200.0 0.01 824037.0 -1370.0 0.0 0.0089 0.609 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P03 compound treatment 899134.0 36300.0 0.05 847692.0 22300.0 0.03 0.0585 0.9705 2071627 Maybridge1_004379 COc1cccc2C(=O)COc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P04 compound treatment 890247.0 27400.0 0.04 829930.0 4520.0 0.01 0.032 0.8109 1045862 Maybridge1_004380 c1c(nc2ccccn12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P05 compound treatment 918804.0 56000.0 0.08 859418.0 34000.0 0.05 0.0898 0.9694 2071628 Maybridge1_004381 O=C(O/N=C/c1ccc2OCOc2c1)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P06 compound treatment 912380.0 49600.0 0.07 873054.0 47600.0 0.07 0.0968 0.9996 2071629 Maybridge1_004382 CC1(C)O[C@H]2CO[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P07 compound treatment 934308.0 71500.0 0.1 865713.0 40300.0 0.06 0.1116 0.961 1133999 Maybridge1_004383 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P08 compound treatment 908842.0 46000.0 0.07 856429.0 31000.0 0.04 0.0769 0.9798 2071630 Maybridge1_004384 C1=CC=CC(C=C1)C2C=CC=CC=C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P09 compound treatment 923619.0 60800.0 0.09 834570.0 9160.0 0.01 0.0702 0.8029 1014809 Maybridge1_004385 O=C1NC(=O)C2(CCCCC2)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P10 compound treatment 925753.0 62900.0 0.09 833331.0 7920.0 0.01 0.0711 0.7884 1454866 Maybridge1_004386 COc1cc(cc(OC)c1OC)c2cc(C(=O)O)c3ccc(C)cc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P11 compound treatment 784503.0 -78300.0 -0.11 729678.0 -95700.0 -0.13 -0.1732 -0.9959 2071631 Maybridge1_004387 Nc1ccc2nonc2c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P12 compound treatment 916788.0 54000.0 0.08 897104.0 71700.0 0.1 0.125 0.9915 2071632 Maybridge1_004388 OC(=O)c1cccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P13 compound treatment 935738.0 72900.0 0.1 882253.0 56800.0 0.08 0.1294 0.9912 2431 Maybridge1_004389 CCN(CC)CCNC(=O)c1ccc(N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P14 compound treatment 920494.0 57700.0 0.08 867010.0 41600.0 0.06 0.099 0.9856 2071633 Maybridge1_004390 Cn1cnc([N+](=O)[O-])c1Sc2nnc(c3ccc(cc3)C(C)(C)C)n2c4ccc5OCOc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P15 compound treatment 931963.0 69100.0 0.1 888757.0 63300.0 0.09 0.132 0.9986 1511723 Maybridge1_004391 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(Cl)c(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P16 compound treatment 936564.0 73700.0 0.1 907995.0 82600.0 0.12 0.1556 0.9989 2071634 Maybridge1_004392 OC(=O)c1ccccc1SCCS(=O)(=O)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P17 compound treatment 962096.0 99300.0 0.14 911285.0 85900.0 0.12 0.1845 0.9967 2071635 Maybridge1_004393 CC(C)(C)c1ccc(cc1)C(=O)O/N=C/2\CCCc3[nH]c4ccccc4c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P18 compound treatment 918305.0 55500.0 0.08 888568.0 63200.0 0.09 0.1181 0.9985 2071636 Maybridge1_004394 Oc1ccc(cc1)n2nnnc2SCC(=O)Nc3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P19 compound treatment 939500.0 76700.0 0.11 901149.0 75700.0 0.11 0.1518 0.9999 1632411 Maybridge1_004395 Cc1ccc(cc1)S(=O)(=O)NC2C(C)(C)C3CC[C@]2(C)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P20 compound treatment 952614.0 89800.0 0.13 864572.0 39200.0 0.05 0.1289 0.9282 2071637 Maybridge1_004396 Cc1ccc(OCC(O)CN2CCN(CC2)c3nc(ns3)c4ccccc4)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P21 compound treatment 934163.0 71300.0 0.1 875572.0 50200.0 0.07 0.1212 0.9835 1113187 Maybridge1_004397 Clc1ccc2noc(c3ccccc3)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P22 compound treatment 934191.0 71400.0 0.1 866963.0 41600.0 0.06 0.1128 0.9647 2071638 Maybridge1_004398 OC(CSc1ccccc1)CN2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P23 compound treatment 910899.0 48100.0 0.07 853659.0 28300.0 0.04 0.0762 0.9657 1555086 Maybridge1_004399 CC(C)(C)OC(=O)N1CCC(CC1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.553 P24 compound treatment 256843.0 -606000.0 -0.86 625886.0 -200000.0 -0.28 -0.8061 -0.8902 2071639 Maybridge1_004400 COc1ccc(cc1)c2ccnc(SCC(=O)c3ccc(Cl)s3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A01 compound treatment 865611.0 272000.0 0.39 823791.0 251000.0 0.35 0.5214 0.9988 1341040 Maybridge1_004401 CC(C)(C)n1nc(cc1N)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A02 compound treatment 838049.0 244000.0 0.35 824776.0 252000.0 0.35 0.4947 1.0 2071640 Maybridge1_004402 COC(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A03 compound treatment 855209.0 262000.0 0.37 825424.0 253000.0 0.35 0.5126 0.9996 2071641 Maybridge1_004403 Fc1cccc(Cl)c1CN/C(=C(\N=C\c2ccccc2)/C#N)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A04 compound treatment 857798.0 264000.0 0.38 833195.0 261000.0 0.36 0.5229 0.9999 2071642 Maybridge1_004404 CC(=O)c1nnc2cc(C)nn2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A05 compound treatment 872920.0 279000.0 0.4 860581.0 288000.0 0.4 0.5651 1.0 2071643 Maybridge1_004405 CN1c2ccccc2C(=O)CS1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A06 compound treatment 920485.0 327000.0 0.46 886545.0 314000.0 0.44 0.6385 0.9996 2071644 Maybridge1_004406 Cc1c(csc1S(=O)(=O)N/N=C/c2c(Cl)cccc2Cl)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A07 compound treatment 897864.0 304000.0 0.43 885976.0 314000.0 0.44 0.6152 1.0 2071645 Maybridge1_004407 CCO/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A08 compound treatment 895965.0 302000.0 0.43 917520.0 345000.0 0.48 0.6444 0.9984 2071646 Maybridge1_004408 CCOC(=O)c1cnc2cc(C)nn2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A09 compound treatment 906809.0 313000.0 0.45 913165.0 341000.0 0.48 0.651 0.9995 1582142 Maybridge1_004409 CC(C)(C)c1ccc(cc1)c2cc(NS(=O)(=O)c3ccccc3)[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A10 compound treatment 921240.0 328000.0 0.47 908208.0 336000.0 0.47 0.6606 1.0 2071647 Maybridge1_004410 CSCCC(CC(=O)O)NC(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A11 compound treatment 922165.0 329000.0 0.47 910374.0 338000.0 0.47 0.6637 1.0 1125786 Maybridge1_004411 Cc1cc(=O)n2ncc(C#N)c2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A12 compound treatment 898540.0 305000.0 0.43 884928.0 313000.0 0.44 0.6148 1.0 2071648 Maybridge1_004412 COC(=O)c1sc(SC)c(c1C)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A13 compound treatment 911922.0 318000.0 0.45 912913.0 340000.0 0.47 0.6559 0.9997 1490917 Maybridge1_004413 O=S(=O)(CCN1CCN(CCS(=O)(=O)c2ccccc2)CC1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A14 compound treatment 899209.0 306000.0 0.43 902674.0 330000.0 0.46 0.633 0.9996 1944746 Maybridge1_004414 CC(=O)c1cnc2cc(nn2c1C)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A15 compound treatment 934470.0 341000.0 0.48 936755.0 364000.0 0.51 0.7021 0.9997 1738962 Maybridge1_004415 COCc1cc(O)nc2n(C)nc(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A16 compound treatment 927122.0 334000.0 0.47 932954.0 361000.0 0.5 0.691 0.9996 2071649 Maybridge1_004416 CCO/C=C(\C#N)/S(=O)(=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A17 compound treatment 919198.0 326000.0 0.46 933947.0 362000.0 0.5 0.684 0.9991 2071650 Maybridge1_004417 COC(=O)c1ccccc1S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A18 compound treatment 936864.0 343000.0 0.49 911500.0 339000.0 0.47 0.6796 0.9999 1242984 Maybridge1_004418 COc1ncccc1C(=O)Nc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A19 compound treatment 941578.0 348000.0 0.49 894735.0 322000.0 0.45 0.6678 0.9988 2071651 Maybridge1_004419 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cccnc2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A20 compound treatment 861549.0 268000.0 0.38 898322.0 326000.0 0.45 0.5909 0.9962 2071652 Maybridge1_004420 Cn1cc(Br)c(n1)c2cccc(N)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A21 compound treatment 876160.0 283000.0 0.4 879183.0 307000.0 0.43 0.5867 0.9995 2071653 Maybridge1_004421 O=S(CC#N)c1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A22 compound treatment 854618.0 261000.0 0.37 832462.0 260000.0 0.36 0.5189 0.9999 1235734 Maybridge1_004422 Cc1ncc(c(N)n1)S(=O)(=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A23 mock treatment 842905.0 249000.0 0.35 828128.0 256000.0 0.36 0.5029 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 A24 mock treatment 130674.0 -463000.0 -0.66 139307.0 -433000.0 -0.6 -0.8926 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B01 compound treatment 848497.0 255000.0 0.36 809542.0 237000.0 0.33 0.4902 0.9989 2071654 Maybridge1_004423 FC(F)(F)c1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B02 compound treatment 873797.0 280000.0 0.4 809584.0 237000.0 0.33 0.5157 0.9957 1515343 Maybridge1_004424 NC(=O)c1ccc(s1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B03 compound treatment 947259.0 354000.0 0.5 844578.0 272000.0 0.38 0.624 0.9904 2071655 Maybridge1_004425 Cc1cc(n2nc(cc2n1)c3ccc(cc3)C(C)(C)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B04 compound treatment 913761.0 320000.0 0.46 883560.0 311000.0 0.43 0.6288 0.9997 2071656 Maybridge1_004426 CCSc1sc(C(=O)OC)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B05 compound treatment 934751.0 341000.0 0.49 925469.0 353000.0 0.49 0.6912 1.0 2071657 Maybridge1_004427 N/C(=N\OC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/CSc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B06 compound treatment 909663.0 316000.0 0.45 897012.0 325000.0 0.45 0.638 1.0 1465696 Maybridge1_004428 CCOC(=O)c1sc(SC)c2C(=O)CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B07 compound treatment 950130.0 357000.0 0.51 951825.0 379000.0 0.53 0.7327 0.9998 2071658 Maybridge1_004429 COC(=O)c1sc(SC)c(C#N)c1c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B08 compound treatment 943816.0 350000.0 0.5 865533.0 293000.0 0.41 0.6412 0.9952 2071659 Maybridge1_004430 CC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CC(C)(C)Cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B09 compound treatment 936719.0 343000.0 0.49 969029.0 397000.0 0.55 0.7362 0.998 2071660 Maybridge1_004431 CC(C)S(=O)(=O)c1cnc(nc1N)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B10 compound treatment 970557.0 377000.0 0.54 979855.0 407000.0 0.57 0.7809 0.9996 2071661 Maybridge1_004432 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)/C(=C/N(C)C)/CCc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B11 compound treatment 926242.0 333000.0 0.47 945330.0 373000.0 0.52 0.7023 0.9989 1242567 Maybridge1_004433 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B12 compound treatment 898926.0 305000.0 0.43 926313.0 354000.0 0.49 0.6561 0.998 2071662 Maybridge1_004434 CNC(=O)c1sc(SC)c2C=CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B13 compound treatment 959181.0 366000.0 0.52 976999.0 405000.0 0.56 0.7666 0.9992 1481192 Maybridge1_004435 CC(C)(C)S(=O)(=O)c1cnc(N)nc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B14 compound treatment 942231.0 349000.0 0.5 971563.0 399000.0 0.56 0.7442 0.9983 2071663 Maybridge1_004436 Cc1csc2sc(COC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B15 compound treatment 882083.0 289000.0 0.41 999439.0 427000.0 0.6 0.7112 0.9835 2071664 Maybridge1_004437 CSc1sc(C(=O)O)c(c1C#N)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B16 compound treatment 908764.0 315000.0 0.45 934697.0 362000.0 0.51 0.6742 0.9982 2071665 Maybridge1_004438 Cn1cncc1S(=O)(=O)/C(=N/Nc2ccc(OC(F)(F)F)cc2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B17 compound treatment 943188.0 350000.0 0.5 993251.0 421000.0 0.59 0.7666 0.9966 2071666 Maybridge1_004439 Cn1ncc(C(=O)N=S(=O)(C)c2ccccc2)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B18 compound treatment 629321.0 35700.0 0.05 677171.0 105000.0 0.15 0.1392 0.9002 1666267 Maybridge1_004440 CCOC(=O)c1sc(c2C(=O)CC(C)(C)Cc12)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B19 compound treatment 928514.0 335000.0 0.48 975568.0 403000.0 0.56 0.7344 0.9966 1154613 Maybridge1_004441 CCCS(=O)(=O)c1cscc1NC(=O)c2c(C)onc2c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B20 compound treatment 903061.0 309000.0 0.44 934753.0 362000.0 0.51 0.6685 0.9976 2071667 Maybridge1_004442 COC(=O)c1sccc1N/C=C(\C#N)/C(=O)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B21 compound treatment 932901.0 339000.0 0.48 857753.0 285000.0 0.4 0.6226 0.9954 2071668 Maybridge1_004443 O=S(=O)(CC#N)Cc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B22 compound treatment 914557.0 321000.0 0.46 890444.0 318000.0 0.44 0.6364 0.9999 2071669 Maybridge1_004444 CC(=O)OCc1ccc(/C=C(/C#N)\S(=O)(=O)c2ccccn2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B23 mock treatment 897123.0 304000.0 0.43 826994.0 255000.0 0.36 0.5563 0.9953 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 B24 mock treatment 136845.0 -457000.0 -0.65 150235.0 -422000.0 -0.59 -0.8756 -0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C01 compound treatment 800815.0 207000.0 0.29 750597.0 178000.0 0.25 0.3841 0.9964 1573411 Maybridge1_004445 Clc1ccc(cc1)S(=O)(=O)CCNC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C02 compound treatment 807538.0 214000.0 0.3 794600.0 222000.0 0.31 0.4343 1.0 2071670 Maybridge1_004446 CSc1sc(C(=O)O)c(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C03 compound treatment 859646.0 266000.0 0.38 819421.0 247000.0 0.34 0.5111 0.9989 2071671 Maybridge1_004447 Brc1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C04 compound treatment 815209.0 222000.0 0.32 833109.0 261000.0 0.36 0.4799 0.9975 1522059 Maybridge1_004448 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C05 compound treatment 809522.0 216000.0 0.31 831587.0 259000.0 0.36 0.4727 0.9967 2071672 Maybridge1_004449 Fc1cccc(Cl)c1CN/C(=C(\NCc2ccccc2Cl)/C#N)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C06 compound treatment 798504.0 205000.0 0.29 842141.0 270000.0 0.38 0.4721 0.992 2071673 Maybridge1_004450 Fc1ccc(SCC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C07 compound treatment 866497.0 273000.0 0.39 848572.0 276000.0 0.39 0.5468 1.0 2071674 Maybridge1_004451 Clc1ccc(cc1)S(=O)(=O)/C(=C/N2CCOCC2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C08 compound treatment 842552.0 249000.0 0.35 891498.0 319000.0 0.45 0.565 0.9936 2071675 Maybridge1_004452 COC(=O)CSCCS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C09 compound treatment 834505.0 241000.0 0.34 891365.0 319000.0 0.44 0.5568 0.9917 2071676 Maybridge1_004453 CN1c2ccccc2C(=O)/C(=N\Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)/S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C10 compound treatment 848483.0 255000.0 0.36 876615.0 304000.0 0.42 0.5563 0.9969 1609422 Maybridge1_004454 COc1cscc1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C11 compound treatment 857045.0 263000.0 0.37 883228.0 311000.0 0.43 0.5714 0.9974 2071677 Maybridge1_004455 Nc1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C12 compound treatment 861303.0 268000.0 0.38 888111.0 316000.0 0.44 0.5805 0.9974 2071678 Maybridge1_004456 COC(=O)c1scc(c1N)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C13 compound treatment 865735.0 272000.0 0.39 907005.0 335000.0 0.47 0.6036 0.9957 1673936 Maybridge1_004457 COCc1cc(=O)n2nc(cc2[nH]1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C14 compound treatment 892114.0 299000.0 0.42 860399.0 288000.0 0.4 0.5842 0.9996 2071679 Maybridge1_004458 CC(=O)c1cnc2cc(C)nn2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C15 compound treatment 892799.0 299000.0 0.43 925815.0 353000.0 0.49 0.6494 0.9973 1413264 Maybridge1_004459 CSc1nc(N)n2nc(cc2n1)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C16 compound treatment 854875.0 261000.0 0.37 900005.0 328000.0 0.46 0.5858 0.9947 2071680 Maybridge1_004460 COC(=O)[C@H](CCSC)NC(=O)c1cccnc1SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C17 compound treatment 838980.0 245000.0 0.35 900232.0 328000.0 0.46 0.57 0.9911 2071681 Maybridge1_004461 CCOC(=O)/C(=N/Nc1cc(Cl)cc(Cl)c1)/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C18 compound treatment 830237.0 237000.0 0.34 894619.0 322000.0 0.45 0.5557 0.9899 2071682 Maybridge1_004462 CCCS(=O)(=O)/C(=C/Nc1ncccn1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C19 compound treatment 881737.0 288000.0 0.41 906409.0 334000.0 0.47 0.6191 0.998 2071683 Maybridge1_004463 N#CCSc1nc2ccccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C20 compound treatment 833188.0 240000.0 0.34 880466.0 308000.0 0.43 0.5447 0.9934 2071684 Maybridge1_004464 CCCS(=O)(=O)c1csc(C(=O)OC)c1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C21 compound treatment 846592.0 253000.0 0.36 912767.0 340000.0 0.47 0.5901 0.9907 2071685 Maybridge1_004465 Cn1nc(cc1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C22 compound treatment 810031.0 216000.0 0.31 826194.0 254000.0 0.35 0.4679 0.9976 2071686 Maybridge1_004466 CS(=O)(=O)c1scc(c1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C23 mock treatment 850035.0 256000.0 0.36 845126.0 273000.0 0.38 0.5268 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 C24 mock treatment 136824.0 -457000.0 -0.65 162609.0 -410000.0 -0.57 -0.8635 -0.998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D01 compound treatment 837705.0 244000.0 0.35 807898.0 235000.0 0.33 0.4777 0.9996 2071687 Maybridge1_004467 Clc1ccc(N/C=C(\C#N)/S(=O)(=O)c2ccccn2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D02 compound treatment 854738.0 261000.0 0.37 803500.0 231000.0 0.32 0.4905 0.9975 2071688 Maybridge1_004468 CC(C)S(=O)(=O)/C(=C/Nc1ccc(Cl)cc1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D03 compound treatment 875954.0 282000.0 0.4 880104.0 308000.0 0.43 0.5874 0.9994 1336734 Maybridge1_004469 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3ccc(OC)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D04 compound treatment 835669.0 242000.0 0.34 805431.0 233000.0 0.32 0.4732 0.9996 2071689 Maybridge1_004470 CCCSc1sc(C(=O)OC)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D05 compound treatment 897172.0 304000.0 0.43 871494.0 299000.0 0.42 0.6002 0.9999 1347108 Maybridge1_004471 COC(=O)C1=C(CSC1)Nc2ccccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D06 compound treatment 856832.0 263000.0 0.37 874097.0 302000.0 0.42 0.5622 0.9983 2071690 Maybridge1_004472 CCOC(=O)CSc1sc(C(=O)OCC)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D07 compound treatment 909269.0 316000.0 0.45 927970.0 356000.0 0.5 0.6681 0.9988 2071691 Maybridge1_004473 CC1(C)OC(=O)C(=CNc2ccccn2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D08 compound treatment 894610.0 301000.0 0.43 904018.0 332000.0 0.46 0.6297 0.9993 2071692 Maybridge1_004474 CCO/C=C(\C#N)/S(=O)(=O)Cc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D09 compound treatment 927835.0 334000.0 0.48 929058.0 357000.0 0.5 0.6878 0.9997 2071693 Maybridge1_004475 COC(=O)c1sc(SC)c(c1N)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D10 compound treatment 897346.0 304000.0 0.43 897337.0 325000.0 0.45 0.6259 0.9997 2071694 Maybridge1_004476 CSc1sc(C#N)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D11 compound treatment 928282.0 335000.0 0.48 929425.0 357000.0 0.5 0.6886 0.9997 1239901 Maybridge1_004477 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D12 compound treatment 869055.0 275000.0 0.39 907568.0 335000.0 0.47 0.6075 0.9961 2071695 Maybridge1_004478 CCOC(=O)c1sc2sc(C#N)c(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D13 compound treatment 914341.0 321000.0 0.46 881961.0 310000.0 0.43 0.6278 0.9996 2071696 Maybridge1_004479 Fc1ccc(NC(=O)CSc2cccs2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D14 compound treatment 882526.0 289000.0 0.41 972454.0 400000.0 0.56 0.6851 0.9887 2071697 Maybridge1_004480 CCOC(=O)c1sc(SC)c(C(=O)C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D15 compound treatment 955035.0 361000.0 0.51 1025639.0 453000.0 0.63 0.8104 0.9947 2071698 Maybridge1_004481 Cc1cscc1S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D16 compound treatment 931002.0 337000.0 0.48 982258.0 410000.0 0.57 0.7435 0.9962 2071699 Maybridge1_004482 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D17 compound treatment 948990.0 355000.0 0.51 968532.0 396000.0 0.55 0.748 0.999 2071700 Maybridge1_004483 COC(=O)C(CCSC)NC(=O)c1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D18 compound treatment 879136.0 286000.0 0.41 937801.0 365000.0 0.51 0.6475 0.9937 1555939 Maybridge1_004484 NNC(=O)CC1Sc2ccccc2NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D19 compound treatment 921788.0 328000.0 0.47 891424.0 319000.0 0.44 0.6446 0.9997 1460263 Maybridge1_004485 CC(C)Sc1c(cnc2n(C)nc(C)c12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D20 compound treatment 874097.0 281000.0 0.4 848818.0 276000.0 0.39 0.5547 0.9999 2071701 Maybridge1_004486 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D21 compound treatment 937529.0 344000.0 0.49 953123.0 381000.0 0.53 0.7213 0.9992 2071702 Maybridge1_004487 NNC(=O)CSCCS(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D22 compound treatment 846600.0 253000.0 0.36 836392.0 264000.0 0.37 0.5148 0.9999 1417176 Maybridge1_004488 CCCSc1sc(C(=O)OCC)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D23 mock treatment 933107.0 340000.0 0.48 892858.0 320000.0 0.45 0.6574 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 D24 mock treatment 128296.0 -465000.0 -0.66 139831.0 -433000.0 -0.6 -0.8945 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E01 compound treatment 830493.0 237000.0 0.34 840154.0 268000.0 0.37 0.5023 0.9987 2071703 Maybridge1_004489 Clc1cccc(/C=C(\C#N)/C(=O)C2CC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E02 compound treatment 801233.0 208000.0 0.3 872124.0 300000.0 0.42 0.5044 0.9855 1003712 Maybridge1_004490 N#CCSc1ccc2ccccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E03 compound treatment 902344.0 309000.0 0.44 941725.0 369000.0 0.52 0.6747 0.9968 2071704 Maybridge1_004491 Clc1ccc(N/N=C(\C#N)/C(=O)C2CC2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E04 compound treatment 875452.0 282000.0 0.4 940972.0 369000.0 0.51 0.6469 0.9924 2071705 Maybridge1_004492 CN1c2ccccc2C(=O)/C(=C\Nc3ccc(F)cc3)/S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E05 compound treatment 876057.0 282000.0 0.4 962038.0 390000.0 0.54 0.6683 0.9889 2071706 Maybridge1_004493 O=C(NC(=S)Nc1cc(n[nH]1)c2cccs2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E06 compound treatment 882840.0 289000.0 0.41 937756.0 365000.0 0.51 0.6512 0.9944 2071707 Maybridge1_004494 Fc1ccc(cc1)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E07 compound treatment 921205.0 328000.0 0.47 978465.0 406000.0 0.57 0.7299 0.9953 2071708 Maybridge1_004495 CN(C)/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E08 compound treatment 895241.0 302000.0 0.43 953978.0 382000.0 0.53 0.6796 0.9943 2071709 Maybridge1_004496 OC(=O)CSCCS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E09 compound treatment 913708.0 320000.0 0.46 983097.0 411000.0 0.57 0.7269 0.9935 2071710 Maybridge1_004497 NC(=S)Nc1ccccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E10 compound treatment 913691.0 320000.0 0.46 940058.0 368000.0 0.51 0.6845 0.9982 1632861 Maybridge1_004498 Clc1ccc(OCc2cccc(C#N)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E11 compound treatment 960889.0 367000.0 0.52 955753.0 383000.0 0.53 0.7474 0.9999 2071711 Maybridge1_004499 Clc1ccc(cc1)S(=O)(=O)/C(=N/Nc2ccccc2Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E12 compound treatment 924690.0 331000.0 0.47 969505.0 397000.0 0.55 0.7246 0.9967 1931850 Maybridge1_004500 OC(=O)CSCCS(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E13 compound treatment 909595.0 316000.0 0.45 1000692.0 428000.0 0.6 0.7401 0.9902 1613806 Maybridge1_004501 COCc1cc(=O)n2nc(C)cc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E14 compound treatment 911889.0 318000.0 0.45 971524.0 399000.0 0.56 0.7137 0.9947 2071712 Maybridge1_004502 Cc1cccc(c1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E15 compound treatment 943419.0 350000.0 0.5 990947.0 419000.0 0.58 0.7645 0.9968 2071713 Maybridge1_004503 CSc1c(C#N)c(nn1C)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E16 compound treatment 927764.0 334000.0 0.48 971524.0 399000.0 0.56 0.7296 0.9969 2071714 Maybridge1_004504 CC(C)(C)S(=O)(=O)/C(=C/N1CCOCC1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E17 compound treatment 921082.0 328000.0 0.47 1033277.0 461000.0 0.64 0.7838 0.9875 2071715 Maybridge1_004505 CSc1nc(nc(c1C#N)c2ccccc2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E18 compound treatment 926482.0 333000.0 0.47 977692.0 405000.0 0.57 0.7344 0.9961 2071716 Maybridge1_004506 FC(F)(F)c1cc(CN/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E19 compound treatment 934164.0 341000.0 0.48 912949.0 341000.0 0.47 0.6783 1.0 2071717 Maybridge1_004507 Cc1n[nH]c(N)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E20 compound treatment 906554.0 313000.0 0.45 1023052.0 451000.0 0.63 0.7591 0.9857 2071718 Maybridge1_004508 COC(=O)c1scc(C#N)c1n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E21 compound treatment 932585.0 339000.0 0.48 928951.0 357000.0 0.5 0.6925 0.9999 2071719 Maybridge1_004509 Clc1ccc(cc1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E22 compound treatment 911931.0 318000.0 0.45 940873.0 368000.0 0.51 0.6835 0.998 2071720 Maybridge1_004510 CS(=O)(=O)c1csc(C(=O)O)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E23 mock treatment 932242.0 339000.0 0.48 869524.0 297000.0 0.41 0.6335 0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 E24 mock treatment 128924.0 -465000.0 -0.66 164809.0 -408000.0 -0.57 -0.8692 -0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F01 compound treatment 885463.0 292000.0 0.42 854496.0 282000.0 0.39 0.5717 0.9996 2071721 Maybridge1_004511 Clc1ccc(Sc2ccccc2/C=C(\C#N)/S(=O)(=O)c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F02 compound treatment 937792.0 344000.0 0.49 884028.0 312000.0 0.43 0.6534 0.9982 2071722 Maybridge1_004512 CC(=O)c1cc(ccc1Sc2ccc(Cl)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F03 compound treatment 978504.0 385000.0 0.55 877339.0 305000.0 0.43 0.6878 0.9922 1672437 Maybridge1_004513 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F04 compound treatment 951253.0 358000.0 0.51 877362.0 305000.0 0.43 0.6604 0.996 1590459 Maybridge1_004514 NC(=S)c1ccc(cc1)C2OCCO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F05 compound treatment 967533.0 374000.0 0.53 919433.0 347000.0 0.48 0.7183 0.9989 2071723 Maybridge1_004515 CCSc1sc(C(=O)OC)c(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F06 compound treatment 944793.0 351000.0 0.5 911156.0 339000.0 0.47 0.6872 0.9996 1200963 Maybridge1_004516 CCOC(=O)c1sc(SC(C)C)c2c1-c3ccccc3N(C)S2(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F07 compound treatment 1016708.0 423000.0 0.6 990621.0 418000.0 0.58 0.8379 0.9999 2071724 Maybridge1_004517 Cc1cc(C)nc(NC=C2C(=O)OC(C)(C)OC2=O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F08 compound treatment 967552.0 374000.0 0.53 986814.0 414000.0 0.58 0.7847 0.9991 2071725 Maybridge1_004518 COC(=O)c1scc(c1N)S(=O)(=O)Cc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F09 compound treatment 946238.0 353000.0 0.5 962096.0 390000.0 0.54 0.7389 0.9992 2071726 Maybridge1_004519 COC(=O)c1sc(SC)c(C#N)c1c2ccc(OC)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F10 compound treatment 949756.0 356000.0 0.51 976189.0 404000.0 0.56 0.7564 0.9986 2071727 Maybridge1_004520 CSc1sc(C#N)c2CCCC(O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F11 compound treatment 1001231.0 408000.0 0.58 1020673.0 448000.0 0.63 0.852 0.9993 2071728 Maybridge1_004521 COC(=O)c1sc(SC)c(c1SC)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F12 compound treatment 949094.0 356000.0 0.51 1002242.0 430000.0 0.6 0.7814 0.9964 1293398 Maybridge1_004522 CCOC(=O)c1sc(c2C(O)CCCc12)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F13 compound treatment 983077.0 389000.0 0.55 1024866.0 452000.0 0.63 0.8379 0.9979 1592097 Maybridge1_004523 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F14 compound treatment 976082.0 383000.0 0.54 994776.0 422000.0 0.59 0.8012 0.9992 1445978 Maybridge1_004524 CCOC(=O)c1sc2sc(C(=O)c3ccc(Cl)cc3)c(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F15 compound treatment 1034131.0 441000.0 0.63 1050819.0 478000.0 0.67 0.9148 0.9995 1390085 Maybridge1_004525 OC(=O)c1sc(SC2CCCCC2)c(C#N)c1c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F16 compound treatment 997477.0 404000.0 0.57 987036.0 415000.0 0.58 0.815 1.0 2071729 Maybridge1_004526 CSc1sc(C#N)c(C)c1C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F17 compound treatment 1024226.0 431000.0 0.61 1046686.0 474000.0 0.66 0.9008 0.9993 2071730 Maybridge1_004527 CC(C)S(=O)(=O)c1csc(C(=O)N)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F18 compound treatment 941211.0 348000.0 0.49 962825.0 390000.0 0.54 0.7346 0.9988 2071731 Maybridge1_004528 CSc1sc(Br)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F19 compound treatment 990235.0 397000.0 0.56 871179.0 299000.0 0.42 0.6935 0.9889 2071732 Maybridge1_004529 FC(F)(F)c1cc(n2ncc(C#N)c2n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F20 compound treatment 925958.0 332000.0 0.47 1004554.0 432000.0 0.6 0.7604 0.9928 2071733 Maybridge1_004530 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F21 compound treatment 981957.0 388000.0 0.55 1054077.0 482000.0 0.67 0.8655 0.9953 1083260 Maybridge1_004531 Cc1ccc(cc1)S(=O)(=O)N=S(=O)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F22 compound treatment 972826.0 379000.0 0.54 952557.0 380000.0 0.53 0.7562 1.0 1056221 Maybridge1_004532 CC(=C(C#N)C#N)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F23 mock treatment 1005748.0 412000.0 0.59 976131.0 404000.0 0.56 0.8126 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 F24 mock treatment 139527.0 -454000.0 -0.65 130643.0 -442000.0 -0.62 -0.8923 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G01 compound treatment 1933940.0 1340000.0 1.91 1473275.0 901000.0 1.26 2.2362 0.9795 2071734 Maybridge1_004533 CN(C)c1ccc(/C=C(\C#N)/C(=O)C2CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G02 compound treatment 853326.0 260000.0 0.37 836124.0 264000.0 0.37 0.5213 1.0 2071735 Maybridge1_004534 O=S(=O)(CC#N)c1ccc2ccccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G03 compound treatment 905432.0 312000.0 0.44 920328.0 348000.0 0.49 0.6567 0.999 2071736 Maybridge1_004535 CC(C)(C)c1ccc(cc1)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G04 compound treatment 855806.0 262000.0 0.37 916483.0 344000.0 0.48 0.603 0.9922 2071737 Maybridge1_004536 Cc1c(csc1C(=O)O)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G05 compound treatment 871864.0 278000.0 0.4 914289.0 342000.0 0.48 0.617 0.9957 2071738 Maybridge1_004537 Brc1ccc(N=Nc2c(NC(=S)NC(=O)c3ccccc3)[nH]nc2C4CC4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G06 compound treatment 893385.0 300000.0 0.43 898264.0 326000.0 0.45 0.6228 0.9995 2071739 Maybridge1_004538 Clc1ccc(cc1Cl)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G07 compound treatment 959638.0 366000.0 0.52 915779.0 343000.0 0.48 0.7067 0.9991 2071740 Maybridge1_004539 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G08 compound treatment 918261.0 325000.0 0.46 936740.0 364000.0 0.51 0.6858 0.9989 2071741 Maybridge1_004540 CC1(C)CC(=O)C(=CNc2ccc(F)cc2F)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G09 compound treatment 957195.0 364000.0 0.52 944202.0 372000.0 0.52 0.7323 1.0 2071742 Maybridge1_004541 Clc1ccc(SCc2cccc(C#N)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G10 compound treatment 879463.0 286000.0 0.41 921980.0 350000.0 0.49 0.6322 0.9959 2071743 Maybridge1_004542 CCSc1sc(C(=O)OC)c(c1C#N)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G11 compound treatment 947129.0 354000.0 0.5 958800.0 386000.0 0.54 0.7366 0.9994 2071744 Maybridge1_004543 Fc1ccc(N/N=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G12 compound treatment 921574.0 328000.0 0.47 990346.0 418000.0 0.58 0.742 0.9939 2071745 Maybridge1_004544 Cc1ccc(cc1)S(=O)(=O)/C(=N/O)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G13 compound treatment 930741.0 337000.0 0.48 966382.0 394000.0 0.55 0.7276 0.9977 2071746 Maybridge1_004545 Cc1cc(C)n2ncc(/C(=N/OC(=O)c3ccccc3Cl)/N)c2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G14 compound treatment 907491.0 314000.0 0.45 954497.0 382000.0 0.53 0.6925 0.9961 2071747 Maybridge1_004546 Clc1ccc(cc1)S(=O)(=O)CCSCCOC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G15 compound treatment 980333.0 387000.0 0.55 1040843.0 468000.0 0.65 0.8509 0.9963 2071748 Maybridge1_004547 Clc1ccc(cc1)S(=O)(=O)C(=C2SCCS2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G16 compound treatment 948096.0 355000.0 0.5 994479.0 422000.0 0.59 0.7727 0.997 2071749 Maybridge1_004548 CSc1ncccc1C(=O)NC(CC(C)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G17 compound treatment 954903.0 361000.0 0.51 1051425.0 479000.0 0.67 0.8357 0.9916 2071750 Maybridge1_004549 CCOC(=O)Cn1nc(C)c(Br)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G18 compound treatment 917215.0 324000.0 0.46 956558.0 384000.0 0.54 0.7043 0.9971 2071751 Maybridge1_004550 COC(=O)c1scc(c1N)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G19 compound treatment 962796.0 369000.0 0.53 927862.0 355000.0 0.5 0.7218 0.9996 2071752 Maybridge1_004551 CC1CN(CC(C)O1)/C=C(\C#N)/S(=O)(=O)Cc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G20 compound treatment 919731.0 326000.0 0.46 990297.0 418000.0 0.58 0.7401 0.9936 2071753 Maybridge1_004552 Nc1ccccc1SCCS(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G21 compound treatment 860635.0 267000.0 0.38 904982.0 333000.0 0.46 0.5965 0.9951 2071754 Maybridge1_004553 CSc1nc(nc(c1C#N)c2ccccc2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G22 compound treatment 895299.0 302000.0 0.43 951019.0 379000.0 0.53 0.6768 0.9947 2071755 Maybridge1_004554 COC(=O)c1scc(c1I)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G23 mock treatment 967513.0 374000.0 0.53 927345.0 355000.0 0.5 0.726 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 G24 mock treatment 129794.0 -464000.0 -0.66 152488.0 -420000.0 -0.59 -0.8805 -0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H01 compound treatment 884977.0 291000.0 0.41 817818.0 245000.0 0.34 0.535 0.9955 2071756 Maybridge1_004555 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2ccc(Cl)cn2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H02 compound treatment 831752.0 238000.0 0.34 846377.0 274000.0 0.38 0.5097 0.9982 2071757 Maybridge1_004556 CC(=O)c1cc([N+](=O)[O-])c(Sc2ccc(Cl)cc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H03 compound treatment 892609.0 299000.0 0.43 861104.0 289000.0 0.4 0.5854 0.9996 1147627 Maybridge1_004557 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H04 compound treatment 837553.0 244000.0 0.35 849079.0 277000.0 0.39 0.5182 0.9986 1550952 Maybridge1_004558 CCOC(=O)c1sc(SC(C)C)c2C(=O)CC(C)(C)Cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H05 compound treatment 940239.0 347000.0 0.49 886570.0 314000.0 0.44 0.6584 0.9983 2071758 Maybridge1_004559 COC(=O)c1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H06 compound treatment 924638.0 331000.0 0.47 918384.0 346000.0 0.48 0.6741 0.9999 2071759 Maybridge1_004560 CSc1sc(C(=O)C)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H07 compound treatment 958962.0 365000.0 0.52 977761.0 405000.0 0.57 0.7672 0.9991 2071760 Maybridge1_004561 CSc1sc(C(=O)O)c(c1C#N)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H08 compound treatment 946767.0 353000.0 0.5 919486.0 347000.0 0.48 0.6974 0.9998 2071761 Maybridge1_004562 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c(c1N)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H09 compound treatment 988188.0 395000.0 0.56 992596.0 420000.0 0.59 0.8112 0.9998 2071762 Maybridge1_004563 CSc1sc(C(=O)O)c(N)c1S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H10 compound treatment 928522.0 335000.0 0.48 945293.0 373000.0 0.52 0.7045 0.999 1553259 Maybridge1_004564 CSc1sc(C(=O)NN)c2CCCC(O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H11 compound treatment 975136.0 382000.0 0.54 969972.0 398000.0 0.55 0.7757 0.9999 2071763 Maybridge1_004565 COC(=O)c1sc(SC)c(c1I)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H12 compound treatment 935956.0 342000.0 0.49 957137.0 385000.0 0.54 0.7237 0.9988 2071764 Maybridge1_004566 CC(=O)c1sc2sc(C#N)c(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H13 compound treatment 931954.0 338000.0 0.48 1002823.0 430000.0 0.6 0.7647 0.994 1735674 Maybridge1_004567 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H14 compound treatment 968999.0 375000.0 0.53 988026.0 416000.0 0.58 0.7874 0.9992 2071765 Maybridge1_004568 CCOC(=O)c1sc2sc(C(=O)C)c(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H15 compound treatment 1019145.0 426000.0 0.61 972326.0 400000.0 0.56 0.8223 0.9992 2071766 Maybridge1_004569 CS(=O)(=NC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H16 compound treatment 982137.0 389000.0 0.55 956711.0 384000.0 0.54 0.7697 0.9999 2071767 Maybridge1_004570 CSc1sc(C(=O)O)c(C)c1C=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H17 compound treatment 967853.0 374000.0 0.53 993199.0 421000.0 0.59 0.7913 0.9988 2071768 Maybridge1_004571 CNC(=S)NNC(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H18 compound treatment 961329.0 368000.0 0.52 974829.0 402000.0 0.56 0.7666 0.9994 2071769 Maybridge1_004572 COc1ccc(cc1)C2CC(=O)c3c(SCc4ccccc4)sc(C#N)c3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H19 compound treatment 993526.0 400000.0 0.57 935068.0 363000.0 0.51 0.7598 0.9983 2071770 Maybridge1_004573 Cc1ccc(cc1)S(=O)(=O)/N=S\2/CCCSC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H20 compound treatment 947863.0 354000.0 0.5 842324.0 270000.0 0.38 0.6224 0.9897 2071771 Maybridge1_004574 COC(=O)c1sccc1N/N=C(\C#N)/S(=O)(=O)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H21 compound treatment 977009.0 383000.0 0.55 975373.0 403000.0 0.56 0.783 0.9999 2071772 Maybridge1_004575 O=C(CSCCS(=O)(=O)c1ccccc1)N/N=C/c2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H22 compound treatment 938778.0 345000.0 0.49 946508.0 374000.0 0.52 0.716 0.9995 2071773 Maybridge1_004576 O=S(=O)(CC#N)Cc1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H23 mock treatment 989697.0 396000.0 0.56 963105.0 391000.0 0.54 0.7836 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 H24 mock treatment 133430.0 -460000.0 -0.65 153316.0 -419000.0 -0.58 -0.876 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I01 compound treatment 857205.0 264000.0 0.37 846333.0 274000.0 0.38 0.5352 1.0 1154606 Maybridge1_004577 Cc1nc2ccc(Br)cc2c(C(=O)O)c1I 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I02 compound treatment 882914.0 289000.0 0.41 893154.0 321000.0 0.45 0.6072 0.9991 2071774 Maybridge1_004578 N/C(=N\OC(=O)c1ccc(Cl)cc1)/CS(=O)(=O)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I03 compound treatment 909484.0 316000.0 0.45 950625.0 378000.0 0.53 0.6906 0.9968 2071775 Maybridge1_004579 Nc1[nH]nc(c1Br)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I04 compound treatment 859669.0 266000.0 0.38 923681.0 351000.0 0.49 0.614 0.9919 2071776 Maybridge1_004580 CN1c2ccccc2C(=O)/C(=C\Nc3ccccn3)/S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I05 compound treatment 887588.0 294000.0 0.42 971250.0 399000.0 0.56 0.689 0.9901 2071777 Maybridge1_004581 Clc1ccc(N=Nc2c(NC(=S)NC(=O)c3ccccc3)[nH]nc2C4CC4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I06 compound treatment 1474892.0 881000.0 1.25 1509571.0 937000.0 1.31 1.8104 0.9998 1023040 Maybridge1_004582 COc1ccc(cc1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I07 compound treatment 908541.0 315000.0 0.45 954742.0 382000.0 0.53 0.6938 0.9962 1033270 Maybridge1_004583 O=S(=O)(CC#N)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I08 compound treatment 866062.0 272000.0 0.39 946063.0 374000.0 0.52 0.6425 0.9894 2071778 Maybridge1_004584 Fc1ccc(NC(=O)CSCCS(=O)(=O)c2ccc(Cl)cc2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I09 compound treatment 954810.0 361000.0 0.51 988238.0 416000.0 0.58 0.7733 0.9982 2071779 Maybridge1_004585 CCOC(=O)c1[nH]c(C)c(C(=O)C)c1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I10 compound treatment 933585.0 340000.0 0.48 982397.0 410000.0 0.57 0.7462 0.9965 2071780 Maybridge1_004586 N/C(=N\O)/c1cccc(COc2ccc(Cl)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I11 compound treatment 915128.0 322000.0 0.46 988613.0 416000.0 0.58 0.7338 0.993 1706372 Maybridge1_004587 Fc1ccccc1C(=O)Nc2ccc(cc2)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I12 compound treatment 922826.0 329000.0 0.47 936710.0 364000.0 0.51 0.6903 0.9992 2071781 Maybridge1_004588 Nc1c(csc1C(=O)O)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I13 compound treatment 982047.0 388000.0 0.55 1003990.0 432000.0 0.6 0.8162 0.9991 2071782 Maybridge1_004589 CC(C)(C)N/C=C(\C#N)/S(=O)(=O)c1ccc(Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I14 compound treatment 928979.0 335000.0 0.48 1002073.0 430000.0 0.6 0.761 0.9936 2071783 Maybridge1_004590 CCSc1ncccc1C(=O)N[C@@H](CCSC)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I15 compound treatment 948711.0 355000.0 0.51 981119.0 409000.0 0.57 0.7602 0.9982 2071784 Maybridge1_004591 COC(=O)c1sc(SC)c(C#N)c1c2cccc(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I16 compound treatment 948879.0 355000.0 0.51 996232.0 424000.0 0.59 0.7752 0.9969 2071785 Maybridge1_004592 CSCCC(NC(=O)c1cccnc1SC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I17 compound treatment 945691.0 352000.0 0.5 1023639.0 451000.0 0.63 0.7991 0.9936 2071786 Maybridge1_004593 Cc1nn(CC(=O)NN)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I18 compound treatment 913881.0 320000.0 0.46 976891.0 404000.0 0.56 0.721 0.9944 2071787 Maybridge1_004594 COC(=O)c1scc(c1N)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I19 compound treatment 964855.0 371000.0 0.53 953311.0 381000.0 0.53 0.749 1.0 2071788 Maybridge1_004595 Clc1ccc(CS(=O)(=O)/C(=C/NCc2cccs2)/C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I20 compound treatment 931666.0 338000.0 0.48 1009490.0 437000.0 0.61 0.771 0.9931 2071789 Maybridge1_004596 COC(=O)c1sc(SC)c(C(=O)C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I21 compound treatment 957915.0 364000.0 0.52 998365.0 426000.0 0.59 0.7864 0.9977 2071790 Maybridge1_004597 Cc1nn(CC#N)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I22 compound treatment 920660.0 327000.0 0.47 953959.0 382000.0 0.53 0.7052 0.9978 2071791 Maybridge1_004598 CSc1nn2c(C)cc(C)nc2c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I23 mock treatment 991740.0 398000.0 0.57 983457.0 411000.0 0.57 0.8057 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 I24 mock treatment 129710.0 -464000.0 -0.66 156815.0 -416000.0 -0.58 -0.8763 -0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J01 compound treatment 875548.0 282000.0 0.4 844741.0 272000.0 0.38 0.5521 0.9996 2071792 Maybridge1_004599 CC(C)S(=O)(=O)C/C(=N/OC(=O)c1cc(Cl)cc(Cl)c1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J02 compound treatment 913364.0 320000.0 0.45 841055.0 269000.0 0.37 0.5865 0.9954 1594963 Maybridge1_004600 NC(=S)CS(=O)(=O)Cc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J03 compound treatment 938521.0 345000.0 0.49 926055.0 354000.0 0.49 0.6956 1.0 2071793 Maybridge1_004601 COC(=O)c1scc(c1Cl)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J04 compound treatment 919013.0 325000.0 0.46 871006.0 299000.0 0.42 0.6217 0.9986 1638468 Maybridge1_004602 CCOC(=O)c1sc(SCc2ccccc2)c3C(=O)CC(C)(C)Cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J05 compound treatment 943778.0 350000.0 0.5 862226.0 290000.0 0.4 0.6379 0.9946 2071794 Maybridge1_004603 Clc1ccc(cc1)C(=O)O/N=C(\C#N)/S(=O)(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J06 compound treatment 942313.0 349000.0 0.5 912294.0 340000.0 0.47 0.6859 0.9997 1255582 Maybridge1_004604 COC(=O)c1sccc1NS(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J07 compound treatment 941642.0 348000.0 0.49 936166.0 364000.0 0.51 0.7087 0.9999 1569903 Maybridge1_004605 CC(C)S(=O)(=O)c1cnc(nc1N)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J08 compound treatment 918262.0 325000.0 0.46 924478.0 352000.0 0.49 0.6737 0.9995 1326008 Maybridge1_004606 CCOC(=O)c1sc(SC)c2C(O)CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J09 compound treatment 987733.0 394000.0 0.56 935983.0 364000.0 0.51 0.7549 0.9987 2071795 Maybridge1_004607 COC(=O)c1scc(c1N/N=C(\C#N)/C(=O)c2ccc(Cl)cc2)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J10 compound treatment 915319.0 322000.0 0.46 935747.0 363000.0 0.51 0.6818 0.9987 2071796 Maybridge1_004608 CC(=O)c1cc([N+](=O)[O-])c(SCCO)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J11 compound treatment 950953.0 357000.0 0.51 934570.0 362000.0 0.51 0.7165 1.0 2071797 Maybridge1_004609 COC(=O)c1sc(SC)c(c1N/N=C(\C#N)/S(=O)(=O)C(C)C)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J12 compound treatment 936374.0 343000.0 0.49 903982.0 332000.0 0.46 0.6717 0.9997 2071798 Maybridge1_004610 COC(=O)c1sc(SC)c2/C(=N\O)/CC(C)(C)Cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J13 compound treatment 941303.0 348000.0 0.49 985243.0 413000.0 0.58 0.7568 0.9971 2071799 Maybridge1_004611 COC(=O)C(CCSC)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J14 compound treatment 927371.0 334000.0 0.47 949636.0 377000.0 0.53 0.7077 0.9987 2071800 Maybridge1_004612 CCOC(=O)CSc1sc(C(=O)OCC)c(C)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J15 compound treatment 951440.0 358000.0 0.51 1003396.0 431000.0 0.6 0.7849 0.9966 2071801 Maybridge1_004613 CN(C)/C=C(\C#N)/S(=O)(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J16 compound treatment 924645.0 331000.0 0.47 945302.0 373000.0 0.52 0.7006 0.9988 2071802 Maybridge1_004614 COC(=O)c1cc(c(s1)S(=O)C)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J17 compound treatment 982637.0 389000.0 0.55 990428.0 418000.0 0.58 0.8035 0.9997 2071803 Maybridge1_004615 Cn1c(S)nnc1c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J18 compound treatment 924424.0 331000.0 0.47 956787.0 384000.0 0.54 0.7117 0.9979 2071804 Maybridge1_004616 COC(=O)c1sc2scc(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J19 compound treatment 973444.0 380000.0 0.54 859686.0 287000.0 0.4 0.6653 0.9892 1717909 Maybridge1_004617 NC(=S)CS(=O)(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J20 compound treatment 931424.0 338000.0 0.48 938513.0 366000.0 0.51 0.7008 0.9995 1134337 Maybridge1_004618 CCOC(=O)c1sc(SCc2ccccc2)c3C(=O)CCCc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J21 compound treatment 972679.0 379000.0 0.54 969184.0 397000.0 0.55 0.7725 0.9999 2071805 Maybridge1_004619 Cc1cc(C)nc(N/C=C(\C#N)/S(=O)(=O)Cc2ccco2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J22 compound treatment 945859.0 352000.0 0.5 939848.0 367000.0 0.51 0.7166 0.9999 2071806 Maybridge1_004620 Cc1c(/C=N/O)c(=O)n(c2ccccc2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J23 mock treatment 912732.0 319000.0 0.45 978038.0 406000.0 0.57 0.7209 0.994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 J24 mock treatment 125194.0 -468000.0 -0.67 161090.0 -411000.0 -0.57 -0.8767 -0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K01 compound treatment 862095.0 269000.0 0.38 846681.0 274000.0 0.38 0.5405 1.0 1662640 Maybridge1_004621 O=C(Nc1cc(n[nH]1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K02 compound treatment 913276.0 320000.0 0.45 858500.0 286000.0 0.4 0.6036 0.9979 2071807 Maybridge1_004622 CCO/C=C(\C#N)/S(=O)(=O)c1ccc2ccccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K03 compound treatment 938268.0 345000.0 0.49 932612.0 360000.0 0.5 0.7018 0.9999 2071808 Maybridge1_004623 Clc1ccc(SCC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K04 compound treatment 827192.0 234000.0 0.33 918034.0 346000.0 0.48 0.5758 0.9835 2071809 Maybridge1_004624 O/N=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K05 compound treatment 916344.0 323000.0 0.46 920441.0 348000.0 0.49 0.6678 0.9996 2071810 Maybridge1_004625 COC(=O)c1cscc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K06 compound treatment 876947.0 283000.0 0.4 920099.0 348000.0 0.48 0.6278 0.9958 2071811 Maybridge1_004626 O/N=C(/C#N)\S(=O)(=O)c1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K07 compound treatment 925452.0 332000.0 0.47 913217.0 341000.0 0.48 0.6698 1.0 2071812 Maybridge1_004627 CCO/C=C(\C#N)/S(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K08 compound treatment 910203.0 317000.0 0.45 853439.0 281000.0 0.39 0.5955 0.9976 2071813 Maybridge1_004628 Nc1cc(n[nH]1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K09 compound treatment 971182.0 378000.0 0.54 928415.0 356000.0 0.5 0.7308 0.9992 1194284 Maybridge1_004629 Nc1c(cnc2cc(nn12)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K10 compound treatment 915319.0 322000.0 0.46 931533.0 359000.0 0.5 0.6777 0.999 1948797 Maybridge1_004630 CCOC(=O)c1cnc2cc(nn2c1C)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K11 compound treatment 881986.0 288000.0 0.41 963279.0 391000.0 0.55 0.6755 0.9902 2071814 Maybridge1_004631 N/C=C(\C#N)/S(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K12 compound treatment 861857.0 268000.0 0.38 901268.0 329000.0 0.46 0.5941 0.9958 2071815 Maybridge1_004632 Nc1cscc1S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K13 compound treatment 902091.0 309000.0 0.44 963508.0 391000.0 0.55 0.6959 0.9942 1989025 Maybridge1_004633 CCOC(=O)c1cn[nH]c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K14 compound treatment 901366.0 308000.0 0.44 941460.0 369000.0 0.51 0.6734 0.9967 2071816 Maybridge1_004634 CCSc1ncccc1C(=O)NC(CCSC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K15 compound treatment 915901.0 322000.0 0.46 987270.0 415000.0 0.58 0.7332 0.9933 2071817 Maybridge1_004635 CCO/C=C(\C#N)/S(=O)(=O)c1ccc(C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K16 compound treatment 889543.0 296000.0 0.42 971896.0 399000.0 0.56 0.6916 0.9904 2071818 Maybridge1_004636 CC(C)(C)S(=O)(=O)/C(=C/N1CCCCC1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K17 compound treatment 925222.0 332000.0 0.47 958316.0 386000.0 0.54 0.7141 0.9978 2071819 Maybridge1_004637 Clc1ccc(CS(=O)(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K18 compound treatment 883325.0 290000.0 0.41 939061.0 367000.0 0.51 0.6529 0.9943 1360241 Maybridge1_004638 COC(=O)C1=C(CSC1)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K19 compound treatment 936765.0 343000.0 0.49 932026.0 360000.0 0.5 0.6997 0.9999 2071820 Maybridge1_004639 CN(C)/C=C/1\C(=O)c2ccccc2N(C)S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K20 compound treatment 882429.0 289000.0 0.41 921003.0 349000.0 0.49 0.6342 0.9965 2071821 Maybridge1_004640 CSc1scc(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K21 compound treatment 958429.0 365000.0 0.52 1004648.0 432000.0 0.6 0.7931 0.9972 2071822 Maybridge1_004641 COC(=O)c1sc(SC)c(c1N)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K22 compound treatment 904338.0 311000.0 0.44 949345.0 377000.0 0.53 0.6842 0.9963 1168939 Maybridge1_004642 CC(C)S(=O)(=O)c1csc(C(=O)O)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K23 mock treatment 965772.0 372000.0 0.53 959219.0 387000.0 0.54 0.7557 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 K24 mock treatment 133461.0 -460000.0 -0.65 150015.0 -422000.0 -0.59 -0.8793 -0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L01 compound treatment 868063.0 274000.0 0.39 817051.0 245000.0 0.34 0.5173 0.9978 2071823 Maybridge1_004643 Clc1ccc(CSc2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L02 compound treatment 846674.0 253000.0 0.36 834138.0 262000.0 0.37 0.5126 1.0 2071824 Maybridge1_004644 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)c(c1)c3cc[nH]n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L03 compound treatment 929281.0 336000.0 0.48 869579.0 297000.0 0.41 0.6306 0.9975 2071825 Maybridge1_004645 O=S(=O)(CCSc1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L04 compound treatment 809625.0 216000.0 0.31 887866.0 315000.0 0.44 0.5283 0.9846 1170462 Maybridge1_004646 CCOC(=O)c1sc(SC)c2c1-c3ccccc3N(C)S2(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L05 compound treatment 1037831.0 444000.0 0.63 965134.0 393000.0 0.55 0.834 0.9975 2071826 Maybridge1_004647 CS(=O)c1noc(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L06 compound treatment 922941.0 329000.0 0.47 867306.0 295000.0 0.41 0.622 0.9979 2071827 Maybridge1_004648 CSc1sc(C#N)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L07 compound treatment 934905.0 341000.0 0.49 925949.0 354000.0 0.49 0.6919 1.0 2071828 Maybridge1_004649 COC(=O)c1scc(c1N/N=C(\C#N)/C(=O)c2ccccc2)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L08 compound treatment 901703.0 308000.0 0.44 849407.0 277000.0 0.39 0.583 0.998 1669213 Maybridge1_004650 CCOC(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CCCc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L09 compound treatment 940726.0 347000.0 0.49 896138.0 324000.0 0.45 0.6683 0.999 2071829 Maybridge1_004651 COC(=O)c1sc(SC)c2C(=O)CC(C)(C)Cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L10 compound treatment 907867.0 314000.0 0.45 910091.0 338000.0 0.47 0.649 0.9997 2071830 Maybridge1_004652 O=C1NCCSC1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L11 compound treatment 959343.0 366000.0 0.52 946163.0 374000.0 0.52 0.7364 1.0 1611340 Maybridge1_004653 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L12 compound treatment 900803.0 307000.0 0.44 882873.0 310000.0 0.43 0.6151 1.0 2071831 Maybridge1_004654 CSc1sc(C(=O)NNC(=O)C)c2CCC=Cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L13 compound treatment 931612.0 338000.0 0.48 939299.0 367000.0 0.51 0.7017 0.9995 2071832 Maybridge1_004655 CS(=O)(=O)c1sc(Cl)c(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L14 compound treatment 865417.0 272000.0 0.39 938549.0 366000.0 0.51 0.6344 0.9906 2071833 Maybridge1_004656 Cc1csc2sc(C(=O)N3CCOCC3)c(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L15 compound treatment 979189.0 386000.0 0.55 942083.0 370000.0 0.52 0.7523 0.9995 2071834 Maybridge1_004657 CCOC(=O)c1sc(SC(C)CC)c(C#N)c1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L16 compound treatment 966264.0 373000.0 0.53 963382.0 391000.0 0.55 0.7603 0.9999 2071835 Maybridge1_004658 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L17 compound treatment 927800.0 334000.0 0.48 997858.0 425000.0 0.59 0.7556 0.994 1322824 Maybridge1_004659 COC(=O)c1sc(N2CCOCC2)c(C#N)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L18 compound treatment 922772.0 329000.0 0.47 942304.0 370000.0 0.52 0.6958 0.9988 2071836 Maybridge1_004660 CSc1sc(C#N)c(C)c1c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L19 compound treatment 916066.0 322000.0 0.46 882776.0 310000.0 0.43 0.6303 0.9996 2071837 Maybridge1_004661 [O-][N+](=O)c1cc(ccc1Sc2ccc(Cl)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L20 compound treatment 946674.0 353000.0 0.5 909612.0 337000.0 0.47 0.6876 0.9995 2071838 Maybridge1_004662 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L21 compound treatment 971213.0 378000.0 0.54 945830.0 373000.0 0.52 0.748 0.9999 2071839 Maybridge1_004663 Cn1ncc(C(=O)N)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L22 compound treatment 924088.0 331000.0 0.47 921654.0 349000.0 0.49 0.6768 0.9998 2071840 Maybridge1_004664 Cc1c(/C=N/OC(=O)c2ccc(Cl)cc2)c(=O)n(c3ccccc3)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L23 mock treatment 1027625.0 434000.0 0.62 927737.0 355000.0 0.5 0.7869 0.9941 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 L24 mock treatment 132361.0 -461000.0 -0.66 150078.0 -422000.0 -0.59 -0.8803 -0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M01 compound treatment 876853.0 283000.0 0.4 825602.0 253000.0 0.35 0.5345 0.9978 1122245 Maybridge1_004665 Clc1ccc(cc1)C(=O)Nc2cc(n[nH]2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M02 compound treatment 835032.0 241000.0 0.34 817541.0 245000.0 0.34 0.4845 1.0 2071841 Maybridge1_004666 CSc1[nH]nc(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M03 compound treatment 887539.0 294000.0 0.42 872936.0 301000.0 0.42 0.592 1.0 2071842 Maybridge1_004667 Fc1cccc(Cl)c1CN/C(=C(\NCc2cccs2)/C#N)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M04 compound treatment 907014.0 313000.0 0.45 866179.0 294000.0 0.41 0.6049 0.9991 2071843 Maybridge1_004668 O/N=C(\C#N)/S(=O)(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M05 compound treatment 925283.0 332000.0 0.47 911087.0 339000.0 0.47 0.6675 1.0 2071844 Maybridge1_004669 CCOC(=O)c1nnc2cc(C)nn2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M06 compound treatment 863598.0 270000.0 0.38 848862.0 276000.0 0.39 0.5441 1.0 1023037 Maybridge1_004670 Clc1cccc(c1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M07 compound treatment 911087.0 318000.0 0.45 904143.0 332000.0 0.46 0.6464 0.9999 2071845 Maybridge1_004671 Cc1cc2nc3CSCc3c(O)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M08 compound treatment 846904.0 253000.0 0.36 882785.0 310000.0 0.43 0.5608 0.9958 2071846 Maybridge1_004672 Cc1cc2ncc(C(=O)O)c(C)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M09 compound treatment 907065.0 313000.0 0.45 860000.0 288000.0 0.4 0.5988 0.9986 1917986 Maybridge1_004673 CCOC(=O)c1[nH]c(C)c(/C(=N/O)/C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M10 compound treatment 909545.0 316000.0 0.45 891488.0 319000.0 0.44 0.6324 1.0 2071847 Maybridge1_004674 CCOC(=O)c1cnc2cc(nn2c1C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M11 compound treatment 981408.0 388000.0 0.55 947789.0 375000.0 0.52 0.7602 0.9997 2071848 Maybridge1_004675 Cc1ccc(cc1)S(=O)(=O)CCN(CCS(=O)(=O)c2ccc(C)cc2)c3ncccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M12 compound treatment 915953.0 322000.0 0.46 938795.0 366000.0 0.51 0.6855 0.9985 2071849 Maybridge1_004676 CSc1nc(C)nc(C2CC2)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M13 compound treatment 922005.0 328000.0 0.47 950625.0 378000.0 0.53 0.7032 0.9982 1147922 Maybridge1_004677 CN(C)C(=O)Oc1cc(C)c2c(C)nn(C)c2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M14 compound treatment 880579.0 287000.0 0.41 928424.0 356000.0 0.5 0.6397 0.9953 2071850 Maybridge1_004678 CC(C)(C)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M15 compound treatment 947222.0 354000.0 0.5 990286.0 418000.0 0.58 0.7677 0.9973 2071851 Maybridge1_004679 COC(=O)c1ccccc1SCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M16 compound treatment 874003.0 280000.0 0.4 933639.0 361000.0 0.5 0.6382 0.9933 2071852 Maybridge1_004680 CCO/C=C(\C#N)/S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M17 compound treatment 944137.0 351000.0 0.5 961310.0 389000.0 0.54 0.736 0.9991 2071853 Maybridge1_004681 Cc1nn(c(C)c1[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M18 compound treatment 904322.0 311000.0 0.44 935921.0 363000.0 0.51 0.671 0.9977 2071854 Maybridge1_004682 COC(=O)c1scc(c1n2cccc2)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M19 compound treatment 921004.0 327000.0 0.47 894246.0 322000.0 0.45 0.6466 0.9998 2071855 Maybridge1_004683 Cc1cc2nnc(C(=O)O)c(C)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M20 compound treatment 905620.0 312000.0 0.44 944775.0 372000.0 0.52 0.681 0.9969 1303068 Maybridge1_004684 Cc1c(cnc2cc(nn12)C(C)(C)C)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M21 compound treatment 957621.0 364000.0 0.52 971407.0 399000.0 0.56 0.7595 0.9993 2071856 Maybridge1_004685 CC(=O)CS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M22 compound treatment 863251.0 270000.0 0.38 949981.0 378000.0 0.53 0.6435 0.9879 1428823 Maybridge1_004686 CCOC(=O)c1c[nH]c2cc(C)nn2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M23 mock treatment 967387.0 374000.0 0.53 907859.0 335000.0 0.47 0.7067 0.998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 M24 mock treatment 625805.0 32200.0 0.05 342538.0 -230000.0 -0.32 -0.1943 -0.5999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N01 compound treatment 909380.0 316000.0 0.45 852302.0 280000.0 0.39 0.5936 0.9976 2071857 Maybridge1_004687 Clc1cccc(Cl)c1/C=C(\C#N)/S(=O)(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N02 compound treatment 911819.0 318000.0 0.45 858966.0 287000.0 0.4 0.6026 0.9981 2071858 Maybridge1_004688 CSc1ccc(cc1c2cc[nH]n2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N03 compound treatment 940047.0 346000.0 0.49 929147.0 357000.0 0.5 0.7002 1.0 2071859 Maybridge1_004689 OC(=O)c1cccc(CSc2cccs2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N04 compound treatment 913319.0 320000.0 0.45 854149.0 282000.0 0.39 0.5994 0.9974 2071860 Maybridge1_004690 CCCCSc1sc(C(=O)OCC)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N05 compound treatment 922755.0 329000.0 0.47 927140.0 355000.0 0.49 0.6808 0.9996 2071861 Maybridge1_004691 O=C(O/N=C(\C#N)/S(=O)(=O)c1cccs1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N06 compound treatment 920371.0 327000.0 0.46 897037.0 325000.0 0.45 0.6487 0.9999 2071862 Maybridge1_004692 CC1(C)CC(=O)c2c(SCc3ccc(Cl)cc3)sc(C#N)c2C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N07 compound treatment 919932.0 326000.0 0.46 874010.0 302000.0 0.42 0.6256 0.9988 1258455 Maybridge1_004693 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N08 compound treatment 885991.0 292000.0 0.42 879471.0 307000.0 0.43 0.5968 0.9999 2071863 Maybridge1_004694 O=S(=O)(Cc1ccco1)C(=C2SCCS2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N09 compound treatment 943049.0 349000.0 0.5 919818.0 347000.0 0.48 0.694 0.9999 2071864 Maybridge1_004695 COc1ccc(cc1)c2c(C#N)c(SC)sc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N10 compound treatment 952379.0 359000.0 0.51 927443.0 355000.0 0.5 0.7109 0.9999 2071865 Maybridge1_004696 CSc1sc(C(=O)C)c(N)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N11 compound treatment 919092.0 326000.0 0.46 971260.0 399000.0 0.56 0.7207 0.9958 1517019 Maybridge1_004697 CC(C)(C)S(=O)(=O)c1cnc(nc1N)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N12 compound treatment 997869.0 404000.0 0.57 993423.0 421000.0 0.59 0.8217 0.9999 2071866 Maybridge1_004698 Nc1c(C#N)sc2sc(C#N)c(c3ccc(Cl)cc3)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N13 compound treatment 907738.0 314000.0 0.45 926331.0 354000.0 0.49 0.6649 0.9988 2071867 Maybridge1_004699 CSc1sc(C(=O)O)c(Cl)c1S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N14 compound treatment 945210.0 352000.0 0.5 850404.0 278000.0 0.39 0.6277 0.9921 1183735 Maybridge1_004700 CSc1sc(C(=O)OCc2ccccc2)c3CC(C)(C)CC(=O)c13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N15 compound treatment 1004733.0 411000.0 0.58 942626.0 370000.0 0.52 0.7785 0.9981 2071868 Maybridge1_004701 CCC(C)Sc1sc(C(=O)O)c(c1C#N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N16 compound treatment 908217.0 315000.0 0.45 911742.0 339000.0 0.47 0.651 0.9996 2071869 Maybridge1_004702 N/C(=C(/N=C/c1ccccc1Sc2ccc(Cl)cc2)\C#N)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N17 compound treatment 947520.0 354000.0 0.5 941422.0 369000.0 0.51 0.7198 0.9999 2071870 Maybridge1_004703 CNC(=S)NNC(=O)Cn1nc(C)c(Br)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N18 compound treatment 944369.0 351000.0 0.5 939947.0 368000.0 0.51 0.7152 0.9999 2071871 Maybridge1_004704 COC(=O)c1sccc1N/N=C(\C#N)/C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N19 compound treatment 978167.0 385000.0 0.55 935548.0 363000.0 0.51 0.7448 0.9993 2071872 Maybridge1_004705 CSc1n[nH]c(N)c1S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N20 compound treatment 960756.0 367000.0 0.52 938768.0 366000.0 0.51 0.7305 0.9999 2071873 Maybridge1_004706 CC(=O)OCc1ccc(/C=C(\C#N)/S(=O)(=O)c2cccs2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N21 compound treatment 981897.0 388000.0 0.55 984691.0 412000.0 0.57 0.7971 0.9998 2071874 Maybridge1_004707 Cc1nc(no1)c2cccc(CSc3nnc(n3C)C(F)(F)F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N22 compound treatment 963795.0 370000.0 0.53 964046.0 392000.0 0.55 0.7585 0.9998 2071875 Maybridge1_004708 CS(=O)c1sc(C#N)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N23 mock treatment 988845.0 395000.0 0.56 971369.0 399000.0 0.56 0.7909 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 N24 mock treatment 599494.0 5910.0 0.01 736850.0 164000.0 0.23 0.1681 0.7325 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O01 compound treatment 882639.0 289000.0 0.41 811884.0 239000.0 0.33 0.5268 0.9947 1610946 Maybridge1_004709 Clc1ccc(cc1)C(=O)Nc2[nH]nc(c2Br)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O02 compound treatment 812178.0 219000.0 0.31 790366.0 218000.0 0.3 0.4347 0.9999 2071876 Maybridge1_004710 O=S(=O)(CC#N)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O03 compound treatment 904668.0 311000.0 0.44 882777.0 310000.0 0.43 0.6189 0.9999 2071877 Maybridge1_004711 Cc1cc(O)n2nc(c(Br)c2n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O04 compound treatment 883795.0 290000.0 0.41 838354.0 266000.0 0.37 0.5541 0.9986 2071878 Maybridge1_004712 Cc1c(csc1C(=O)NN)S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O05 compound treatment 921487.0 328000.0 0.47 867618.0 295000.0 0.41 0.6209 0.9981 2071879 Maybridge1_004713 COc1cscc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O06 compound treatment 873741.0 280000.0 0.4 843789.0 271000.0 0.38 0.5493 0.9997 2071880 Maybridge1_004714 Cc1ccc(cc1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O07 compound treatment 921548.0 328000.0 0.47 909680.0 337000.0 0.47 0.6624 1.0 2071881 Maybridge1_004715 CN1c2ccccc2C(=O)/C(=N\Nc3ccccc3F)/S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O08 compound treatment 917163.0 324000.0 0.46 885285.0 313000.0 0.44 0.6339 0.9996 2071882 Maybridge1_004716 N/C(=N\O)/c1cccc(CS(=O)(=O)c2ccccn2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O09 compound treatment 944000.0 350000.0 0.5 844476.0 272000.0 0.38 0.6207 0.991 2071883 Maybridge1_004717 Fc1ccc(N/C(=C\C#N)/c2ccccc2Cl)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O10 compound treatment 887302.0 294000.0 0.42 877283.0 305000.0 0.43 0.596 1.0 1586034 Maybridge1_004718 CCOC(=O)c1cnc2cc(nn2c1C)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O11 compound treatment 917165.0 324000.0 0.46 892618.0 320000.0 0.45 0.6412 0.9999 1435418 Maybridge1_004719 Cc1ccc(cc1)S(=O)(=O)CCN2CCN(CCS(=O)(=O)c3ccc(C)cc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O12 compound treatment 860604.0 267000.0 0.38 883624.0 311000.0 0.43 0.5754 0.9978 2071884 Maybridge1_004720 OCCSCCS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O13 compound treatment 926011.0 332000.0 0.47 896671.0 324000.0 0.45 0.6541 0.9998 2071885 Maybridge1_004721 CSc1nc(N)n2nc(C)cc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O14 compound treatment 910375.0 317000.0 0.45 896846.0 324000.0 0.45 0.6385 1.0 1329939 Maybridge1_004722 COc1ncccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O15 compound treatment 919468.0 326000.0 0.46 922305.0 350000.0 0.49 0.6728 0.9997 2071886 Maybridge1_004723 CCOC(=O)/C(=N\Nc1ccc(F)cc1F)/C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O16 compound treatment 880988.0 287000.0 0.41 870527.0 298000.0 0.42 0.583 1.0 1061097 Maybridge1_004724 Cc1cc(C)c2ccc(N)nc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O17 compound treatment 927311.0 334000.0 0.47 943676.0 371000.0 0.52 0.7017 0.9991 2071887 Maybridge1_004725 COc1sc(/C=N/O)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O18 compound treatment 890880.0 297000.0 0.42 891917.0 319000.0 0.45 0.614 0.9997 2071888 Maybridge1_004726 COC(=O)c1scc(c1Cl)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O19 compound treatment 926589.0 333000.0 0.47 874660.0 302000.0 0.42 0.6329 0.9983 2071889 Maybridge1_004727 O=S(=O)(CC#N)c1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O20 compound treatment 907065.0 313000.0 0.45 877912.0 305000.0 0.43 0.6165 0.9997 1521014 Maybridge1_004728 Clc1ccc(cc1)c2cc3ncc(cn3n2)S(=O)(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O21 compound treatment 934950.0 341000.0 0.49 927674.0 355000.0 0.5 0.6936 0.9999 2071890 Maybridge1_004729 COC(=O)c1sc(SC)c(C#N)c1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O22 compound treatment 872336.0 279000.0 0.4 886667.0 314000.0 0.44 0.5902 0.9987 1278022 Maybridge1_004730 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O23 mock treatment 953375.0 360000.0 0.51 918637.0 346000.0 0.48 0.7032 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 O24 mock treatment 506017.0 -87600.0 -0.12 538640.0 -33800.0 -0.05 -0.1214 -0.9116 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P01 compound treatment 862242.0 269000.0 0.38 794169.0 222000.0 0.31 0.4888 0.9945 2071891 Maybridge1_004731 N/C(=N\O)/CS(=O)(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P02 compound treatment 890429.0 297000.0 0.42 832685.0 260000.0 0.36 0.5552 0.9972 2071892 Maybridge1_004732 Brc1ccc(s1)c2cc[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P03 compound treatment 898540.0 305000.0 0.43 838937.0 267000.0 0.37 0.5695 0.9971 2071893 Maybridge1_004733 Cc1cc(nc2c([N+](=O)[O-])c(nn12)C(C)(C)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P04 compound treatment 889517.0 296000.0 0.42 857791.0 285000.0 0.4 0.579 0.9996 1542166 Maybridge1_004734 CCOC(=O)c1sc(SC(C)C)c2C(=O)CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P05 compound treatment 930033.0 336000.0 0.48 868742.0 296000.0 0.41 0.6306 0.9973 2071894 Maybridge1_004735 CC1(C)OC(=O)C(=CNc2ccc(F)c(Cl)c2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P06 compound treatment 934905.0 341000.0 0.49 869391.0 297000.0 0.41 0.6361 0.9969 2071895 Maybridge1_004736 CSc1sc(C(=O)/C=C/N(C)C)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P07 compound treatment 967853.0 374000.0 0.53 880032.0 308000.0 0.43 0.6797 0.9943 2071896 Maybridge1_004737 CSC(=C(C#N)S(=O)(=O)C(C)C)SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P08 compound treatment 953038.0 359000.0 0.51 840938.0 269000.0 0.37 0.6263 0.9883 2071897 Maybridge1_004738 CCOC(=O)c1sc(SC)c(C#N)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P09 compound treatment 945404.0 352000.0 0.5 872802.0 300000.0 0.42 0.65 0.9961 1253540 Maybridge1_004739 CCCS(=O)(=O)c1cnc(C)nc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P10 compound treatment 922932.0 329000.0 0.47 859340.0 287000.0 0.4 0.6141 0.9969 2071898 Maybridge1_004740 Cc1c(sc2sc(C(=O)O)c(C)c12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P11 compound treatment 904914.0 311000.0 0.44 853484.0 281000.0 0.39 0.5902 0.9982 1012008 Maybridge1_004741 CN(C)CCC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P12 compound treatment 925602.0 332000.0 0.47 890904.0 318000.0 0.44 0.648 0.9995 2071899 Maybridge1_004742 Cc1csc2sc(CO)c(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P13 compound treatment 928630.0 335000.0 0.48 876899.0 304000.0 0.42 0.6372 0.9984 2071900 Maybridge1_004743 CSc1sc(C(=O)O)c(C)c1C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P14 compound treatment 922305.0 329000.0 0.47 870285.0 298000.0 0.42 0.6243 0.9983 1410702 Maybridge1_004744 CSc1sc(C(=O)OCC=C)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P15 compound treatment 947966.0 354000.0 0.5 873931.0 302000.0 0.42 0.6537 0.996 2071901 Maybridge1_004745 CSc1sc(Br)c(Cl)c1S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P16 compound treatment 952493.0 359000.0 0.51 889952.0 318000.0 0.44 0.6741 0.9975 1123577 Maybridge1_004746 CCOC(=O)CC1Sc2ccccc2NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P17 compound treatment 946025.0 352000.0 0.5 906435.0 334000.0 0.47 0.6838 0.9993 1646261 Maybridge1_004747 COC(=O)c1sc(N2CCCCC2)c(C#N)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P18 compound treatment 937666.0 344000.0 0.49 900568.0 328000.0 0.46 0.6696 0.9994 2071902 Maybridge1_004748 COC(=O)c1sccc1N/N=C(\C#N)/C(=O)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P19 compound treatment 943538.0 350000.0 0.5 865364.0 293000.0 0.41 0.6408 0.9952 1280343 Maybridge1_004749 Cc1ccc(cc1)S(=O)(=O)N=S2(=O)CCCS(=O)(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P20 compound treatment 951553.0 358000.0 0.51 855465.0 283000.0 0.39 0.6391 0.9921 2071903 Maybridge1_004750 CC(=O)OCc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P21 compound treatment 910779.0 317000.0 0.45 878744.0 306000.0 0.43 0.6211 0.9996 2071904 Maybridge1_004751 CC(C)(C)OC(=O)NC(CC(=O)N)C(=O)Oc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P22 compound treatment 849766.0 256000.0 0.36 819338.0 247000.0 0.34 0.5011 0.9996 2071905 Maybridge1_004752 CC1(C)CC(=O)c2c(sc(C#N)c2C1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P23 mock treatment 918445.0 325000.0 0.46 838303.0 266000.0 0.37 0.5889 0.9941 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.554 P24 mock treatment 533925.0 -59700.0 -0.08 274519.0 -298000.0 -0.42 -0.3538 -0.8343 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A01 compound treatment 862511.0 258000.0 0.37 824902.0 229000.0 0.32 0.4848 0.9976 1151876 Maybridge1_004753 CCOC(=O)c1sc(SCC)c2C(=O)CC(C)(C)Cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A02 compound treatment 854293.0 250000.0 0.35 815428.0 219000.0 0.31 0.4672 0.9972 3177140 Maybridge1_004754 Cc1cc(C)c(c(C)c1)S(=O)(=O)O.Clc1ccc(cc1)S(=N)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A03 compound treatment 865372.0 261000.0 0.37 830557.0 234000.0 0.33 0.4932 0.998 2071907 Maybridge1_004755 CCSc1sc(C#N)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A04 compound treatment 870827.0 266000.0 0.38 839139.0 243000.0 0.34 0.5072 0.9985 3177141 Maybridge1_004756 CS(=N)c1ccsc1.Cc1cc(C)c(c(C)c1)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A05 compound treatment 905654.0 301000.0 0.43 847261.0 251000.0 0.35 0.5502 0.995 1678777 Maybridge1_004757 NS(=O)(=O)c1ccc(Sc2ccc(Cl)cc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A06 compound treatment 921619.0 317000.0 0.45 864913.0 269000.0 0.37 0.5837 0.9958 1150718 Maybridge1_004758 NNC(=O)C1SCCN1S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A07 compound treatment 935613.0 331000.0 0.47 871659.0 275000.0 0.38 0.6044 0.9949 2071909 Maybridge1_004759 COc1ccc(cc1)c2ccnc(S)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A08 compound treatment 927578.0 323000.0 0.46 881865.0 286000.0 0.4 0.6064 0.9975 2071910 Maybridge1_004760 OC(=O)c1ccc(CSc2ccc(cn2)C(F)(F)F)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A09 compound treatment 931811.0 327000.0 0.47 827483.0 231000.0 0.32 0.557 0.984 2071911 Maybridge1_004761 O=C(NCc1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A10 compound treatment 891828.0 287000.0 0.41 863675.0 267000.0 0.37 0.5525 0.999 2071912 Maybridge1_004762 CSc1ccc(OC(=O)Nc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A11 compound treatment 912801.0 308000.0 0.44 881786.0 286000.0 0.4 0.5915 0.9989 2071913 Maybridge1_004763 CSc1nnc(c2cccs2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A12 compound treatment 933387.0 329000.0 0.47 895681.0 299000.0 0.42 0.6259 0.9984 1448822 Maybridge1_004764 NNC(=O)CNS(=O)(=O)c1cccc2nsnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A13 compound treatment 913371.0 309000.0 0.44 886675.0 290000.0 0.41 0.5969 0.9992 2071914 Maybridge1_004765 CNc1ccc(CSc2ccc(cn2)C(F)(F)F)cc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A14 compound treatment 939261.0 335000.0 0.48 902445.0 306000.0 0.43 0.6384 0.9986 1026900 Maybridge1_004766 N=C(Nc1ccccc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A15 compound treatment 955139.0 350000.0 0.5 924380.0 328000.0 0.46 0.676 0.9991 2071915 Maybridge1_004767 CCOC(=O)c1ncn(Cc2ccc(Cl)cc2)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A16 compound treatment 945257.0 341000.0 0.48 897112.0 301000.0 0.42 0.6392 0.9975 2071916 Maybridge1_004768 Clc1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A17 compound treatment 961120.0 356000.0 0.51 911087.0 315000.0 0.44 0.6689 0.9974 2071917 Maybridge1_004769 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)c3cnccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A18 compound treatment 936755.0 332000.0 0.47 898205.0 302000.0 0.42 0.6317 0.9984 1087586 Maybridge1_004770 Cc1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A19 compound treatment 951272.0 347000.0 0.49 911251.0 315000.0 0.44 0.6592 0.9984 2071918 Maybridge1_004771 FC(F)(F)c1ccc(nc1)S(=O)(=O)/C(=C/Nc2ccc3OCCOc3c2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A20 compound treatment 924991.0 320000.0 0.46 880000.0 284000.0 0.4 0.602 0.9976 1774528 Maybridge1_004772 OC(=O)Cc1n[nH]c(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A21 compound treatment 905644.0 301000.0 0.43 857433.0 261000.0 0.36 0.5602 0.9968 2071919 Maybridge1_004773 COC(=O)c1cccc(CSc2nnc(n2C)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A22 compound treatment 863089.0 258000.0 0.37 848446.0 252000.0 0.35 0.5086 0.9998 1507929 Maybridge1_004774 COC(=O)c1sccc1NS(=O)(=O)c2cccc3nsnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A23 mock treatment 854043.0 249000.0 0.35 820347.0 224000.0 0.31 0.4718 0.998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 A24 mock treatment 149512.0 -455000.0 -0.65 140355.0 -456000.0 -0.64 -0.9073 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B01 compound treatment 845748.0 241000.0 0.34 798794.0 203000.0 0.28 0.4422 0.9954 1573898 Maybridge1_004775 CC1=Cn2n(C1)c(=O)c3ccccc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B02 compound treatment 881470.0 277000.0 0.39 849931.0 254000.0 0.35 0.5285 0.9986 2071920 Maybridge1_004776 CC1=CS(=O)(=O)c2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B03 compound treatment 932864.0 328000.0 0.47 877657.0 281000.0 0.39 0.6076 0.9963 2071921 Maybridge1_004777 NNC(=O)CSc1cc(nc2ccccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B04 compound treatment 932405.0 328000.0 0.47 869235.0 273000.0 0.38 0.5988 0.995 2071922 Maybridge1_004778 [O-][N+](=O)c1ccc(cc1)N2CCC(CC2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B05 compound treatment 965463.0 361000.0 0.51 919652.0 323000.0 0.45 0.6818 0.9979 1644315 Maybridge1_004779 Clc1ccccc1n2cc(C#N)c(=O)[nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B06 compound treatment 867774.0 263000.0 0.37 913492.0 317000.0 0.44 0.5775 0.9965 2071923 Maybridge1_004780 CCOC(=O)NC(=O)/C(=C/Nc1sc(C)c(C)c1C(=O)OCC)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B07 compound treatment 1071422.0 467000.0 0.66 950186.0 354000.0 0.49 0.8184 0.9894 1717562 Maybridge1_004781 CC(C)n1cc(C(=S)N)c(=O)n(Cc2ccccc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B08 compound treatment 958952.0 354000.0 0.5 857806.0 262000.0 0.36 0.6142 0.9874 2071924 Maybridge1_004782 CC(=O)Nc1cc(n[nH]1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B09 compound treatment 998333.0 394000.0 0.56 959781.0 364000.0 0.51 0.7544 0.9988 2071925 Maybridge1_004783 O=C1N(CCCCN2CCN(CC2)C(c3ccccc3)c4ccccc4)C(=O)c5ccccc15 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B10 compound treatment 972267.0 368000.0 0.52 937338.0 341000.0 0.48 0.706 0.9989 2071926 Maybridge1_004784 CN1CCN(CC1)/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B11 compound treatment 984491.0 380000.0 0.54 916336.0 320000.0 0.45 0.6976 0.9955 2071927 Maybridge1_004785 FC(F)(F)c1ccc(nc1)n2ccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B12 compound treatment 901181.0 296000.0 0.42 868172.0 272000.0 0.38 0.5663 0.9986 1042218 Maybridge1_004786 OC(=O)c1cc2cccc([N+](=O)[O-])c2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B13 compound treatment 988766.0 384000.0 0.55 905695.0 309000.0 0.43 0.6914 0.9932 2071928 Maybridge1_004787 O/N=C/c1ccc(C#Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B14 compound treatment 927247.0 323000.0 0.46 913319.0 317000.0 0.44 0.6371 0.9998 2071929 Maybridge1_004788 O/N=C/1\CCCc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B15 compound treatment 962854.0 358000.0 0.51 905322.0 309000.0 0.43 0.665 0.9966 1076140 Maybridge1_004789 CSc1ncc(C#N)c(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B16 compound treatment 961981.0 357000.0 0.51 930069.0 334000.0 0.47 0.6885 0.9991 2071930 Maybridge1_004790 CN(C)c1ncnc(N(C)C)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B17 compound treatment 951890.0 347000.0 0.49 915979.0 320000.0 0.45 0.6645 0.9987 2071931 Maybridge1_004791 COC(=O)C(C#N)c1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B18 compound treatment 930419.0 326000.0 0.46 879679.0 283000.0 0.4 0.6071 0.9969 2071932 Maybridge1_004792 CCCCC#Cc1ccc(o1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B19 compound treatment 980491.0 376000.0 0.53 947753.0 352000.0 0.49 0.7246 0.9991 1585976 Maybridge1_004793 NC(=O)CCOC1CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B20 compound treatment 901223.0 297000.0 0.42 885878.0 290000.0 0.4 0.5839 0.9998 2071933 Maybridge1_004794 CCOC(=O)CCN(Cc1ccco1)S(=O)(=O)c2ccc(s2)c3ccnc(SC)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B21 compound treatment 943390.0 339000.0 0.48 907952.0 312000.0 0.43 0.648 0.9987 2071934 Maybridge1_004795 CSc1nn(cc1C(=S)N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B22 compound treatment 917809.0 313000.0 0.45 879793.0 284000.0 0.4 0.5945 0.9983 1302174 Maybridge1_004796 Cc1ccccc1n2c(N)cc(=O)[nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B23 mock treatment 941901.0 337000.0 0.48 873315.0 277000.0 0.39 0.6124 0.9943 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 B24 mock treatment 158848.0 -446000.0 -0.63 150089.0 -446000.0 -0.62 -0.8883 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C01 compound treatment 733536.0 129000.0 0.18 719618.0 123000.0 0.17 0.2513 0.9995 2071935 Maybridge1_004797 CC1(C)CC(=O)c2c(sc(Br)c2C1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C02 compound treatment 805041.0 200000.0 0.28 812642.0 216000.0 0.3 0.4149 0.9996 2071936 Maybridge1_004798 FC(F)(F)c1cnc(Sc2cccs2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C03 compound treatment 849370.0 245000.0 0.35 864388.0 268000.0 0.37 0.5105 0.9993 1490688 Maybridge1_004799 CSc1sc(C(=S)N)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C04 compound treatment 816463.0 212000.0 0.3 851865.0 256000.0 0.36 0.4651 0.9965 3177144 Maybridge1_004800 CS(=N)c1ncc(Cl)cc1C(F)(F)F.Cc1cc(C)c(c(C)c1)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C05 compound treatment 866761.0 262000.0 0.37 885910.0 290000.0 0.4 0.5492 0.9992 2071938 Maybridge1_004801 NNS(=O)(=O)c1ccc(s1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C06 compound treatment 846889.0 242000.0 0.34 871369.0 275000.0 0.38 0.5149 0.9985 2071939 Maybridge1_004802 CC(=O)c1ccc2OCCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C07 compound treatment 887090.0 282000.0 0.4 887718.0 292000.0 0.41 0.5715 1.0 2071940 Maybridge1_004803 NC(=S)CSc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C08 compound treatment 769750.0 165000.0 0.23 885187.0 289000.0 0.4 0.451 0.9669 2071941 Maybridge1_004804 C1Cc2cc(ccc2O1)c3cc[nH]n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C09 compound treatment 848952.0 244000.0 0.35 914860.0 319000.0 0.44 0.5599 0.9926 2071942 Maybridge1_004805 O=S(=O)(NCc1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C10 compound treatment 803828.0 199000.0 0.28 857944.0 262000.0 0.37 0.4584 0.9921 2071943 Maybridge1_004806 COC(=O)c1cccc(Cn2nc(C)c(Br)c2C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C11 compound treatment 819339.0 215000.0 0.31 914376.0 318000.0 0.44 0.5296 0.9833 1920568 Maybridge1_004807 Clc1ccc(NC(=O)c2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C12 compound treatment 796488.0 192000.0 0.27 870097.0 274000.0 0.38 0.463 0.9864 1087839 Maybridge1_004808 COc1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C13 compound treatment 822290.0 218000.0 0.31 886839.0 291000.0 0.41 0.5054 0.9911 1068635 Maybridge1_004809 O=S(=O)(c1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C14 compound treatment 843612.0 239000.0 0.34 907790.0 312000.0 0.43 0.5475 0.9926 2071944 Maybridge1_004810 Sc1nnc(CSCCOc2ccc(Cl)cc2Cl)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C15 compound treatment 852641.0 248000.0 0.35 935113.0 339000.0 0.47 0.5836 0.9896 2071945 Maybridge1_004811 [O-][N+](=O)c1cc(cs1)S(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C16 compound treatment 811625.0 207000.0 0.29 893634.0 297000.0 0.41 0.5014 0.9859 2071946 Maybridge1_004812 C/C(=N\O)/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C17 compound treatment 806103.0 201000.0 0.29 901686.0 305000.0 0.43 0.5038 0.9813 2071947 Maybridge1_004813 CS(=O)(=O)c1sc(Cl)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C18 compound treatment 3122580.0 2520000.0 3.58 3269879.0 2670000.0 3.73 5.1687 0.9998 2071948 Maybridge1_004814 [O-][N+](=O)c1ccc(N2CCCCC2)c3nonc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C19 compound treatment 899109.0 294000.0 0.42 898983.0 303000.0 0.42 0.5947 1.0 2071949 Maybridge1_004815 CC1(C)CCc2cc(/C=C(\C#N)/S(=O)(=O)C)ccc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C20 compound treatment 823573.0 219000.0 0.31 868884.0 273000.0 0.38 0.489 0.9951 1517114 Maybridge1_004816 CCOC(=O)Cc1n[nH]c(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C21 compound treatment 823257.0 219000.0 0.31 871478.0 275000.0 0.38 0.4913 0.9945 2071950 Maybridge1_004817 CSc1sc(c2cc[nH]n2)c(c1C#N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C22 compound treatment 805753.0 201000.0 0.29 839256.0 243000.0 0.34 0.4419 0.9964 1032639 Maybridge1_004818 COc1cc(Cl)c(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C23 mock treatment 857425.0 253000.0 0.36 843863.0 248000.0 0.35 0.4984 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 C24 mock treatment 159529.0 -445000.0 -0.63 133377.0 -463000.0 -0.65 -0.9041 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D01 compound treatment 879607.0 275000.0 0.39 812868.0 217000.0 0.3 0.4901 0.9919 2071951 Maybridge1_004819 Oc1cc(nc2cc(Cl)cc(Cl)c12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D02 compound treatment 893816.0 289000.0 0.41 885083.0 289000.0 0.4 0.5756 0.9999 2071952 Maybridge1_004820 COc1ccc(cc1)C(=O)/C(=C/NC2CCN(Cc3ccccc3)CC2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D03 compound treatment 944285.0 340000.0 0.48 930114.0 334000.0 0.47 0.6708 0.9998 1578495 Maybridge1_004821 NC(=O)C1CCN(CCS(=O)(=O)c2ccc(Cl)cc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D04 compound treatment 931702.0 327000.0 0.47 895400.0 299000.0 0.42 0.6239 0.9985 2071953 Maybridge1_004822 COC(=O)c1cc(ccc1N2CCC(CC2)n3cccc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D05 compound treatment 999925.0 395000.0 0.56 973287.0 377000.0 0.53 0.7693 0.9994 2071954 Maybridge1_004823 [O-][N+](=O)c1c(Sc2ccc(cn2)C(F)(F)F)ncnc1Sc3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D06 compound treatment 866738.0 262000.0 0.37 890224.0 294000.0 0.41 0.5535 0.9989 1005737 Maybridge1_004824 [O-][N+](=O)c1cccc(C=C(C#N)C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D07 compound treatment 1024398.0 420000.0 0.6 958029.0 362000.0 0.5 0.7789 0.9965 2071955 Maybridge1_004825 NCCSc1cc(nc2ccccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D08 compound treatment 912130.0 307000.0 0.44 949681.0 353000.0 0.49 0.6577 0.9982 1144898 Maybridge1_004826 Cc1nn(C)c2ncc3c(=O)[nH]n(C)c3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D09 compound treatment 986643.0 382000.0 0.54 961990.0 366000.0 0.51 0.7448 0.9995 2071956 Maybridge1_004827 CNc1ncnc(Oc2cccc(c2)C(F)(F)F)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D10 compound treatment 929791.0 325000.0 0.46 951582.0 355000.0 0.5 0.6774 0.9994 2071957 Maybridge1_004828 Cn1c(S)nnc1CSCC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D11 compound treatment 913303.0 309000.0 0.44 1022825.0 427000.0 0.6 0.7311 0.9888 2071958 Maybridge1_004829 O=C(Nc1cccc(C#C)c1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D12 compound treatment 961607.0 357000.0 0.51 858431.0 262000.0 0.37 0.6175 0.9871 1634031 Maybridge1_004830 CCCn1c(=O)c(C#N)cn(c2ccc(Cl)cc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D13 compound treatment 982687.0 378000.0 0.54 955753.0 360000.0 0.5 0.7347 0.9994 2071959 Maybridge1_004831 CC(C)(O)C#Cc1ccc(/C=N/O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D14 compound treatment 925407.0 321000.0 0.46 927398.0 331000.0 0.46 0.6491 1.0 1465353 Maybridge1_004832 COc1ccc(cc1OC2CCCC2)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D15 compound treatment 989606.0 385000.0 0.55 947939.0 352000.0 0.49 0.7339 0.9985 1914741 Maybridge1_004833 OC(=O)CSc1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D16 compound treatment 987935.0 383000.0 0.54 937510.0 341000.0 0.48 0.722 0.9977 2071960 Maybridge1_004834 CCCCC#Cc1cncc(c1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D17 compound treatment 976171.0 371000.0 0.53 963824.0 368000.0 0.51 0.7361 0.9999 1341007 Maybridge1_004835 Clc1ccc(cc1Cl)C(=O)CSC2=NCCc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D18 compound treatment 889879.0 285000.0 0.41 897579.0 301000.0 0.42 0.584 0.9998 2071961 Maybridge1_004836 Oc1cc(nc2c(cccc12)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D19 compound treatment 982747.0 378000.0 0.54 996643.0 400000.0 0.56 0.7751 0.9998 2071962 Maybridge1_004837 CN(C)CC#Cc1cccc(/C=N/O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D20 compound treatment 927434.0 323000.0 0.46 945267.0 349000.0 0.49 0.6688 0.9996 2071963 Maybridge1_004838 CCOC(=O)c1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D21 compound treatment 960736.0 356000.0 0.51 987300.0 391000.0 0.55 0.7437 0.9993 2071964 Maybridge1_004839 NC(=O)C1CCN(CC1)c2ncc(Cl)cc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D22 compound treatment 891217.0 287000.0 0.41 945265.0 349000.0 0.49 0.6324 0.9961 2071965 Maybridge1_004840 Cn1c(SCC(=O)Nc2ccc(cc2)C(F)(F)F)nnc1c3ccc4nonc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D23 mock treatment 964480.0 360000.0 0.51 954188.0 358000.0 0.5 0.7148 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 D24 mock treatment 131345.0 -473000.0 -0.67 153253.0 -443000.0 -0.62 -0.9128 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E01 compound treatment 850507.0 246000.0 0.35 839088.0 243000.0 0.34 0.4867 0.9999 1679279 Maybridge1_004841 CCOC(=O)c1sc(SCC=C)c2C(=O)CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E02 compound treatment 886781.0 282000.0 0.4 919661.0 323000.0 0.45 0.6026 0.9983 2071966 Maybridge1_004842 CCOC(=O)c1ccc(Oc2sccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E03 compound treatment 964017.0 359000.0 0.51 1009596.0 413000.0 0.58 0.769 0.9982 2071967 Maybridge1_004843 Clc1ccc(cc1)S(=O)(=O)CCN(Cc2cccs2)/C=C(\C#N)/S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E04 compound treatment 931909.0 327000.0 0.47 917529.0 321000.0 0.45 0.6459 0.9998 2071968 Maybridge1_004844 FC(F)(F)c1cccc(NC(=O)Nc2cnn3c(cc(nc23)C(F)(F)F)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E05 compound treatment 913561.0 309000.0 0.44 924672.0 328000.0 0.46 0.6345 0.9998 2071969 Maybridge1_004845 Clc1ccc(/C=N/NS(=O)(=O)c2ccc(s2)c3ccccn3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E06 compound treatment 942240.0 338000.0 0.48 975775.0 380000.0 0.53 0.7138 0.9988 1313983 Maybridge1_004846 CC(=O)N1CCSC1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E07 compound treatment 1006030.0 401000.0 0.57 1009956.0 414000.0 0.58 0.8116 1.0 1397201 Maybridge1_004847 CCOC(=O)c1c(C)nsc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E08 compound treatment 901156.0 296000.0 0.42 952182.0 356000.0 0.5 0.6492 0.9967 2071970 Maybridge1_004848 FC(F)(F)c1ccc(SCc2ccc(o2)C(=O)Oc3ccccc3)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E09 compound treatment 987208.0 383000.0 0.54 1014347.0 418000.0 0.58 0.797 0.9994 2071971 Maybridge1_004849 Cn1c(S)nnc1CSc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E10 compound treatment 955914.0 351000.0 0.5 985595.0 389000.0 0.54 0.7372 0.9991 1445026 Maybridge1_004850 Cc1nn(Cc2cccc(c2)C(=O)O)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E11 compound treatment 979955.0 375000.0 0.53 1017352.0 421000.0 0.59 0.7927 0.9989 2071972 Maybridge1_004851 O=S(=O)(c1ccsc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E12 compound treatment 921039.0 316000.0 0.45 948925.0 353000.0 0.49 0.666 0.999 2071973 Maybridge1_004852 Clc1ccc(SCC#N)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E13 compound treatment 958258.0 354000.0 0.5 961953.0 366000.0 0.51 0.7162 1.0 2071974 Maybridge1_004853 COC(=O)C1=C(CSC1)OS(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E14 compound treatment 923364.0 319000.0 0.45 934516.0 338000.0 0.47 0.6541 0.9998 1552646 Maybridge1_004854 CS(=O)c1ccc(Oc2cccc(F)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E15 compound treatment 977642.0 373000.0 0.53 1033288.0 437000.0 0.61 0.8061 0.9976 1323369 Maybridge1_004855 Cc1c(ncn1Cc2ccc(Cl)cc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E16 compound treatment 903948.0 299000.0 0.43 960392.0 364000.0 0.51 0.6601 0.9961 2071975 Maybridge1_004856 CC(=O)NCCc1ccc(OC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E17 compound treatment 973787.0 369000.0 0.52 996500.0 400000.0 0.56 0.7659 0.9995 2071976 Maybridge1_004857 CS(=O)c1sc(Cl)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E18 compound treatment 1.7439034E7 1.68E7 23.94 1.7294962E7 1.67E7 23.29 33.3964 0.9999 2071977 Maybridge1_004858 [O-][N+](=O)c1ccc(N2CCCC2)c3nonc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E19 compound treatment 1009775.0 405000.0 0.58 997261.0 401000.0 0.56 0.8029 0.9999 2071978 Maybridge1_004859 O=C1CSC(C1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E20 compound treatment 977989.0 373000.0 0.53 1013623.0 417000.0 0.58 0.787 0.9989 2071979 Maybridge1_004860 CSc1nn2c(cc(nc2c1C(=O)N)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E21 compound treatment 1008341.0 404000.0 0.57 1002688.0 406000.0 0.57 0.8068 1.0 2071980 Maybridge1_004861 [O-][N+](=O)c1ccsc1Sc2ccc(cn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E22 compound treatment 953752.0 349000.0 0.5 977019.0 381000.0 0.53 0.7266 0.9994 2071981 Maybridge1_004862 N/C(=N\O)/COc1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E23 mock treatment 930150.0 325000.0 0.46 960689.0 364000.0 0.51 0.6867 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 E24 mock treatment 162242.0 -442000.0 -0.63 156553.0 -440000.0 -0.61 -0.8785 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F01 compound treatment 880048.0 275000.0 0.39 808011.0 212000.0 0.3 0.4858 0.9903 2071982 Maybridge1_004863 Oc1cc(nc2cc(Cl)ccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F02 compound treatment 920994.0 316000.0 0.45 899871.0 304000.0 0.42 0.6175 0.9995 1426067 Maybridge1_004864 O=C(N1CCC(CC1)n2cccc2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F03 compound treatment 982507.0 378000.0 0.54 989748.0 394000.0 0.55 0.768 0.9999 1407522 Maybridge1_004865 NC(=O)C1CCN(CCC#N)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F04 compound treatment 946284.0 342000.0 0.49 924044.0 328000.0 0.46 0.6668 0.9995 2071983 Maybridge1_004866 [O-][N+](=O)c1cc(ccc1N2CCC(CC2)n3cccc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F05 compound treatment 954102.0 349000.0 0.5 1001202.0 405000.0 0.56 0.7508 0.998 2071984 Maybridge1_004867 CSc1nn(c(N)c1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F06 compound treatment 964652.0 360000.0 0.51 971270.0 375000.0 0.52 0.7318 0.9999 1579683 Maybridge1_004868 CCCn1c(=O)c(C#N)nn(c2ccccc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F07 compound treatment 1011510.0 407000.0 0.58 1017802.0 422000.0 0.59 0.8249 1.0 1545160 Maybridge1_004869 CCOC(=O)NC(=O)c1cn(C(C)C)c(=O)n(Cc2ccccc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F08 compound treatment 948487.0 344000.0 0.49 937320.0 341000.0 0.48 0.6821 0.9999 2071985 Maybridge1_004870 NS(=O)(=O)c1cc([N+](=O)[O-])c(s1)N2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F09 compound treatment 1001439.0 397000.0 0.56 996622.0 400000.0 0.56 0.7938 1.0 1229841 Maybridge1_004871 Cc1[nH]c2ccccc2c1SCc3nnc(S)n3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F10 compound treatment 956596.0 352000.0 0.5 953328.0 357000.0 0.5 0.7061 1.0 1160768 Maybridge1_004872 OC(=O)c1c(nnc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F11 compound treatment 966546.0 362000.0 0.51 996891.0 401000.0 0.56 0.759 0.9992 2071986 Maybridge1_004873 CC(=O)c1ccc(C#Cc2ccccc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F12 compound treatment 983708.0 379000.0 0.54 991608.0 395000.0 0.55 0.7711 0.9999 2071987 Maybridge1_004874 Cc1ccc2snc(C(=O)N)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F13 compound treatment 1037931.0 433000.0 0.62 958514.0 362000.0 0.51 0.793 0.9952 2071988 Maybridge1_004875 NC(CC(=O)O)c1ccccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F14 compound treatment 979209.0 375000.0 0.53 973895.0 378000.0 0.53 0.7491 1.0 2071989 Maybridge1_004876 OC(=O)c1cc2cc(OC(F)(F)F)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F15 compound treatment 1081854.0 477000.0 0.68 1091589.0 495000.0 0.69 0.9684 1.0 1013621 Maybridge1_004877 CSc1ncc(C(=O)N)c(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F16 compound treatment 999285.0 395000.0 0.56 981109.0 385000.0 0.54 0.7764 0.9998 2071990 Maybridge1_004878 CSc1nccc(n1)c2ccc(s2)S(=O)(=O)N(CCC#N)Cc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F17 compound treatment 1025639.0 421000.0 0.6 1017597.0 421000.0 0.59 0.8389 1.0 1635590 Maybridge1_004879 O=C(Nc1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F18 compound treatment 971534.0 367000.0 0.52 964084.0 368000.0 0.51 0.7317 1.0 2071991 Maybridge1_004880 Cc1cccc2c(O)cc(nc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F19 compound treatment 1022912.0 418000.0 0.59 972777.0 377000.0 0.53 0.7919 0.9981 2071992 Maybridge1_004881 NNC(=O)CN1C(=O)CSc2ccc(cc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F20 compound treatment 986602.0 382000.0 0.54 992219.0 396000.0 0.55 0.7746 1.0 2071993 Maybridge1_004882 CCOC1O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O1)n3cnc4c(N)ncnc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F21 compound treatment 1030707.0 426000.0 0.61 996305.0 400000.0 0.56 0.823 0.9992 2071994 Maybridge1_004883 N#Cc1cncc(C#Cc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F22 compound treatment 975006.0 370000.0 0.53 920969.0 325000.0 0.45 0.6927 0.9972 2071995 Maybridge1_004884 COC(=O)c1c(C)oc(=O)c(Br)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F23 mock treatment 1002750.0 398000.0 0.57 1000123.0 404000.0 0.56 0.7986 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 F24 mock treatment 154500.0 -450000.0 -0.64 158020.0 -438000.0 -0.61 -0.8848 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G01 compound treatment 863413.0 259000.0 0.37 769052.0 173000.0 0.24 0.4306 0.979 2071996 Maybridge1_004885 NS(=O)(=O)c1ccc(Br)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G02 compound treatment 847068.0 242000.0 0.34 867587.0 271000.0 0.38 0.5114 0.9989 2071997 Maybridge1_004886 [O-][N+](=O)c1ccsc1NCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G03 compound treatment 935050.0 330000.0 0.47 970158.0 374000.0 0.52 0.701 0.9986 2071998 Maybridge1_004887 CSc1sc(c2CC(C)(C)CC(=O)c12)c3ccnc(S)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G04 compound treatment 910134.0 305000.0 0.43 933278.0 337000.0 0.47 0.6396 0.9992 2071999 Maybridge1_004888 Sc1nccc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G05 compound treatment 926108.0 321000.0 0.46 975312.0 379000.0 0.53 0.6971 0.9974 2072000 Maybridge1_004889 Cn1nc(cc1N)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G06 compound treatment 818845.0 214000.0 0.3 860697.0 264000.0 0.37 0.4762 0.9955 2072001 Maybridge1_004890 FC(F)(F)c1cnc(N2CCSCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G07 compound treatment 960182.0 355000.0 0.51 948804.0 353000.0 0.49 0.7052 0.9999 2072002 Maybridge1_004891 CN1c2sc(C)c(C)c2C(=O)CS1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G08 compound treatment 886333.0 282000.0 0.4 952529.0 356000.0 0.5 0.6346 0.9943 1408174 Maybridge1_004892 COC(=O)C1SCCN1C(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G09 compound treatment 914054.0 309000.0 0.44 955678.0 359000.0 0.5 0.6656 0.9979 2072003 Maybridge1_004893 CCOC(=O)c1sc(SC)c2/C(=N\OC)/CCCc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G10 compound treatment 881213.0 277000.0 0.39 917067.0 321000.0 0.45 0.5945 0.9979 2072004 Maybridge1_004894 C/C(=N\OCC(=O)O)/c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G11 compound treatment 916345.0 312000.0 0.44 991323.0 395000.0 0.55 0.703 0.9942 2072005 Maybridge1_004895 Cc1nn(Cc2nnc(S)o2)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G12 compound treatment 892626.0 288000.0 0.41 919783.0 324000.0 0.45 0.6086 0.9988 2072006 Maybridge1_004896 Clc1ccc(c(Cl)c1)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G13 compound treatment 839096.0 234000.0 0.33 948795.0 353000.0 0.49 0.5834 0.9821 2072007 Maybridge1_004897 FC(F)(F)Oc1ccc(cc1)C(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G14 compound treatment 941817.0 337000.0 0.48 918078.0 322000.0 0.45 0.6564 0.9995 2072008 Maybridge1_004898 CC1(C)Oc2ccc(C#N)cc2C=C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G15 compound treatment 951515.0 347000.0 0.49 987894.0 392000.0 0.55 0.735 0.9987 2072009 Maybridge1_004899 CSc1sc(Cl)c2CC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G16 compound treatment 972837.0 368000.0 0.52 970402.0 374000.0 0.52 0.7392 1.0 2072010 Maybridge1_004900 C/C(=N\OCc1cccc(c1)C(=O)O)/c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G17 compound treatment 989262.0 385000.0 0.55 997518.0 401000.0 0.56 0.7825 0.9999 2072011 Maybridge1_004901 CSc1scc2CCc3cnc(S)nc3-c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G18 compound treatment 711191.0 106000.0 0.15 749531.0 153000.0 0.21 0.2583 0.9857 1931686 Maybridge1_004902 Cc1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G19 compound treatment 966411.0 362000.0 0.51 1000340.0 404000.0 0.56 0.7623 0.999 2072012 Maybridge1_004903 CN1c2ccccc2C(=O)/C(=C/N=S(=O)(C)C)/S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G20 compound treatment 947259.0 343000.0 0.49 947779.0 352000.0 0.49 0.6912 1.0 1025517 Maybridge1_004904 NNC(=O)C1COc2ccccc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G21 compound treatment 914314.0 310000.0 0.44 974898.0 379000.0 0.53 0.6848 0.9959 1593337 Maybridge1_004905 Cc1cc(C)n(n1)c2ncc(C#N)c(N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G22 compound treatment 897846.0 293000.0 0.42 946712.0 351000.0 0.49 0.6405 0.9969 2072013 Maybridge1_004906 Cc1ccc2nc(cc(O)c2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G23 mock treatment 956795.0 352000.0 0.5 956104.0 360000.0 0.5 0.709 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 G24 mock treatment 150895.0 -454000.0 -0.65 151325.0 -445000.0 -0.62 -0.8951 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H01 compound treatment 877067.0 272000.0 0.39 816270.0 220000.0 0.31 0.4909 0.9934 2072014 Maybridge1_004907 CC(C)Oc1cc(nc2ccc(CSCCO)cc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H02 compound treatment 864681.0 260000.0 0.37 861410.0 265000.0 0.37 0.523 1.0 1164963 Maybridge1_004908 Fc1ccc(cc1)S(=O)(=O)Cc2noc(n2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H03 compound treatment 944471.0 340000.0 0.48 918795.0 323000.0 0.45 0.6598 0.9994 2072015 Maybridge1_004909 NC(=O)C1CCN(CC1)c2ccc(cn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H04 compound treatment 923055.0 318000.0 0.45 916657.0 320000.0 0.45 0.6362 1.0 2072016 Maybridge1_004910 [O-][N+](=O)c1ccc(N2CCC(CC2)n3cccc3)c(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H05 compound treatment 958981.0 354000.0 0.5 975056.0 379000.0 0.53 0.7299 0.9997 2072017 Maybridge1_004911 CSc1nn(cc1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H06 compound treatment 939553.0 335000.0 0.48 963816.0 368000.0 0.51 0.6993 0.9993 2072018 Maybridge1_004912 CCCn1c(=O)c(nn(c2cccc(c2)C(F)(F)F)c1=O)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H07 compound treatment 956900.0 352000.0 0.5 954176.0 358000.0 0.5 0.7072 1.0 2072019 Maybridge1_004913 COc1ccc(cc1)S(=O)(=O)NCCSc2cc(nc3ccccc23)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H08 compound treatment 924220.0 320000.0 0.45 890699.0 294000.0 0.41 0.6117 0.9987 2072020 Maybridge1_004914 CC(=O)c1ccc(C#Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H09 compound treatment 978019.0 373000.0 0.53 944008.0 348000.0 0.49 0.7184 0.999 2072021 Maybridge1_004915 Clc1ccc(SCC2N3CCC(CC3)C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H10 compound treatment 920442.0 316000.0 0.45 926793.0 331000.0 0.46 0.6435 0.9999 2072022 Maybridge1_004916 CC(C)(C)c1cc2nc(cc(N3CCN(CC3)c4cc(nc5cc(nn45)C(C)(C)C)C(F)(F)F)n2n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H11 compound treatment 977663.0 373000.0 0.53 970245.0 374000.0 0.52 0.7439 1.0 1619884 Maybridge1_004917 Cn1ccnc1SCc2nccn2Cc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H12 compound treatment 914280.0 310000.0 0.44 946859.0 351000.0 0.49 0.6571 0.9986 2072023 Maybridge1_004918 OC(=O)CSc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H13 compound treatment 968620.0 364000.0 0.52 947361.0 351000.0 0.49 0.7123 0.9996 2072024 Maybridge1_004919 CC(C)(O)C#Cc1ccc(/C=N/Nc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H14 compound treatment 920153.0 315000.0 0.45 930230.0 334000.0 0.47 0.6466 0.9998 1019296 Maybridge1_004920 NC(=O)CCSCCC(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H15 compound treatment 958819.0 354000.0 0.5 950307.0 354000.0 0.49 0.7053 1.0 2072025 Maybridge1_004921 Cc1c(Br)sc2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H16 compound treatment 974319.0 370000.0 0.53 930069.0 334000.0 0.47 0.7009 0.9982 2072026 Maybridge1_004922 CCCCCCC#Cc1cncc(c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H17 compound treatment 971770.0 367000.0 0.52 970655.0 374000.0 0.52 0.7384 1.0 1555072 Maybridge1_004923 Clc1cc(Cl)cc(NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H18 compound treatment 925665.0 321000.0 0.46 921126.0 325000.0 0.45 0.6432 1.0 2072027 Maybridge1_004924 Oc1cc(nc2ccc(cc12)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H19 compound treatment 978802.0 374000.0 0.53 970050.0 374000.0 0.52 0.7449 0.9999 1254018 Maybridge1_004925 OC(=O)c1cncc(C#Cc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H20 compound treatment 968932.0 364000.0 0.52 952455.0 356000.0 0.5 0.7176 0.9998 2072028 Maybridge1_004926 NNC(=O)c1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H21 compound treatment 977020.0 372000.0 0.53 943170.0 347000.0 0.48 0.7166 0.999 1012399 Maybridge1_004927 [O-][N+](=O)c1ccc(Oc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H22 compound treatment 942259.0 338000.0 0.48 912432.0 316000.0 0.44 0.6513 0.9991 2072029 Maybridge1_004928 FC(F)(F)c1cc(no1)c2ccc(s2)S(=O)(=O)N3CCC(CC3)C(c4ccccc4)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H23 mock treatment 1022153.0 417000.0 0.59 970206.0 374000.0 0.52 0.7886 0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 H24 mock treatment 152519.0 -452000.0 -0.64 150382.0 -446000.0 -0.62 -0.8944 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I01 compound treatment 852588.0 248000.0 0.35 829188.0 233000.0 0.32 0.479 0.9992 2072030 Maybridge1_004929 Cc1cc(O)c2nncn2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I02 compound treatment 917644.0 313000.0 0.45 886138.0 290000.0 0.4 0.6006 0.9989 2072031 Maybridge1_004930 Clc1ccc(cc1)S(=O)(=O)CCC2CCCCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I03 compound treatment 923604.0 319000.0 0.45 938376.0 342000.0 0.48 0.6581 0.9997 2072032 Maybridge1_004931 CSc1scc2CC(C)(C)C/C(=N/O)/c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I04 compound treatment 927826.0 323000.0 0.46 929291.0 333000.0 0.46 0.6534 1.0 2072033 Maybridge1_004932 NS(=O)(=O)c1ccc(Sc2cccs2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I05 compound treatment 913026.0 308000.0 0.44 980093.0 384000.0 0.54 0.6886 0.9951 2072034 Maybridge1_004933 CC1(C)CC(=O)C=C(Sc2ccc(C#N)cc2[N+](=O)[O-])S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I06 compound treatment 869383.0 265000.0 0.38 935495.0 339000.0 0.47 0.6008 0.9936 2072035 Maybridge1_004934 CC(=O)CSc1sc(C(=O)C)c(c1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I07 compound treatment 945006.0 340000.0 0.48 967368.0 371000.0 0.52 0.7082 0.9994 2072036 Maybridge1_004935 CSc1nccc(n1)c2ccc(Br)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I08 compound treatment 888502.0 284000.0 0.4 970402.0 374000.0 0.52 0.6544 0.9919 2072037 Maybridge1_004936 CCOC(=O)c1cnc(SCC(=O)c2ccc(Cl)cc2Cl)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I09 compound treatment 910417.0 306000.0 0.43 959162.0 363000.0 0.51 0.6654 0.9971 1569480 Maybridge1_004937 COC(=O)C1=C(CSC1)Nc2ccc(O)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I10 compound treatment 909517.0 305000.0 0.43 937820.0 342000.0 0.48 0.6434 0.9989 1043570 Maybridge1_004938 Nc1cccc2nsnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I11 compound treatment 955725.0 351000.0 0.5 973228.0 377000.0 0.53 0.7248 0.9997 2072038 Maybridge1_004939 CN1c2ccccc2C(=C(C(=O)Nc3ccc(OC(F)(F)F)cc3)S1(=O)=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I12 compound treatment 918227.0 314000.0 0.45 952615.0 356000.0 0.5 0.6668 0.9985 2072039 Maybridge1_004940 CSc1ccc(OS(=O)(=O)c2cc(cs2)S(=O)(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I13 compound treatment 965530.0 361000.0 0.51 951498.0 355000.0 0.5 0.7132 0.9998 2072040 Maybridge1_004941 COC(=O)c1cscc1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I14 compound treatment 939692.0 335000.0 0.48 994160.0 398000.0 0.56 0.7293 0.9971 1068477 Maybridge1_004942 Clc1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I15 compound treatment 992321.0 388000.0 0.55 985607.0 389000.0 0.54 0.7738 1.0 2072041 Maybridge1_004943 CSc1sc(c(C)c1c2cc[nH]n2)c3nc(C)cs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I16 compound treatment 952266.0 348000.0 0.49 936010.0 340000.0 0.47 0.6846 0.9998 2072042 Maybridge1_004944 C/C(=N\OCc1cccc(c1)C(=O)O)/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I17 compound treatment 945728.0 341000.0 0.48 988694.0 392000.0 0.55 0.73 0.9982 2072043 Maybridge1_004945 CSc1nc(N)nc(n1)c2cnccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I18 compound treatment 833339.0 229000.0 0.33 828718.0 233000.0 0.32 0.4592 1.0 2072044 Maybridge1_004946 OCCSc1ccc([N+](=O)[O-])c2nonc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I19 compound treatment 893187.0 288000.0 0.41 931262.0 335000.0 0.47 0.6205 0.9979 2072045 Maybridge1_004947 C1CSC(S1)C2CSC(C2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I20 compound treatment 966904.0 362000.0 0.52 946692.0 350000.0 0.49 0.7099 0.9997 1153413 Maybridge1_004948 CCOC(=O)Cc1nn(CC(=S)N)c(=O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I21 compound treatment 953422.0 349000.0 0.5 1015531.0 419000.0 0.58 0.7642 0.9966 2072046 Maybridge1_004949 CSc1nnc(n1C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I22 compound treatment 967223.0 363000.0 0.52 978365.0 382000.0 0.53 0.7414 0.9999 2072047 Maybridge1_004950 Clc1ccc(OC(=O)c2csc(COc3ccc4nonc4c3)n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I23 mock treatment 978703.0 374000.0 0.53 967300.0 371000.0 0.52 0.7421 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 I24 mock treatment 154573.0 -450000.0 -0.64 155275.0 -441000.0 -0.61 -0.8875 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J01 compound treatment 892378.0 288000.0 0.41 837676.0 241000.0 0.34 0.5274 0.9953 1736035 Maybridge1_004951 Cc1nn(Cc2ccc(o2)C(=O)O)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J02 compound treatment 901596.0 297000.0 0.42 903560.0 307000.0 0.43 0.6017 1.0 2072048 Maybridge1_004952 Fc1ccc(cc1)S(=O)(=O)Cc2noc(n2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J03 compound treatment 963219.0 359000.0 0.51 975510.0 379000.0 0.53 0.7346 0.9998 1428447 Maybridge1_004953 CCOC(=O)NC(=O)c1cn(Cc2cccs2)c(=O)[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J04 compound treatment 896471.0 292000.0 0.41 912363.0 316000.0 0.44 0.6052 0.9995 2072049 Maybridge1_004954 O=C1NC(=O)N2CSCC21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J05 compound treatment 944157.0 339000.0 0.48 926846.0 331000.0 0.46 0.6674 0.9997 2072050 Maybridge1_004955 CC(C)n1cc(C#N)c(=O)[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J06 compound treatment 904270.0 300000.0 0.43 924877.0 329000.0 0.46 0.6254 0.9993 1270484 Maybridge1_004956 CCOC(=O)c1c(Oc2ccccc2)c3cc(Cl)ccc3nc1SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J07 compound treatment 960631.0 356000.0 0.51 928692.0 332000.0 0.46 0.6858 0.999 2072051 Maybridge1_004957 CC(=O)c1ccc(C#CC(C)(C)O)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J08 compound treatment 923310.0 319000.0 0.45 993568.0 397000.0 0.55 0.7123 0.995 2072052 Maybridge1_004958 C/C(=N\Nc1c(Cl)cc(Cl)cc1Cl)/c2ccc(C#CCC3CCCCC3)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J09 compound treatment 991251.0 387000.0 0.55 1016934.0 421000.0 0.59 0.8036 0.9995 2072053 Maybridge1_004959 CCOC(=O)Cn1cc(C#N)c(=O)[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J10 compound treatment 931479.0 327000.0 0.46 938860.0 343000.0 0.48 0.6665 0.9999 2072054 Maybridge1_004960 CCCN(C(=O)CC#N)C(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J11 compound treatment 960574.0 356000.0 0.51 990825.0 395000.0 0.55 0.747 0.9991 1072028 Maybridge1_004961 OCc1nccn1Cc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J12 compound treatment 959619.0 355000.0 0.5 936501.0 340000.0 0.47 0.6925 0.9995 1166253 Maybridge1_004962 COC(=O)c1cccc(NC(=O)NCc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J13 compound treatment 983117.0 378000.0 0.54 995926.0 400000.0 0.56 0.7747 0.9998 1052980 Maybridge1_004963 OC(=O)CSc1ncccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J14 compound treatment 830408.0 226000.0 0.32 888601.0 292000.0 0.41 0.5153 0.993 2072055 Maybridge1_004964 CCOC(=O)c1cnc2ccc(OC(F)(F)F)cc2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J15 compound treatment 982927.0 378000.0 0.54 991079.0 395000.0 0.55 0.7698 0.9999 2072056 Maybridge1_004965 O/N=C/c1ccc(Br)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J16 compound treatment 937155.0 332000.0 0.47 949878.0 354000.0 0.49 0.6831 0.9998 2072057 Maybridge1_004966 Oc1cc(nc2c(Cl)cccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J17 compound treatment 942047.0 337000.0 0.48 965269.0 369000.0 0.51 0.7032 0.9994 2072058 Maybridge1_004967 COc1cc(nc2ccc(C)c([N+](=O)[O-])c12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J18 compound treatment 961387.0 357000.0 0.51 938504.0 342000.0 0.48 0.6963 0.9995 2072059 Maybridge1_004968 Oc1cc(nc2cc(ccc12)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J19 compound treatment 989849.0 385000.0 0.55 988229.0 392000.0 0.55 0.7739 1.0 2072060 Maybridge1_004969 CCOC(=O)C(Cc1cc([N+](=O)[O-])c(Oc2ccc(OC)cc2)c(c1)[N+](=O)[O-])NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J20 compound treatment 975904.0 371000.0 0.53 956890.0 361000.0 0.5 0.729 0.9997 2072061 Maybridge1_004970 N#CCCOCC1CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J21 compound treatment 998632.0 394000.0 0.56 916249.0 320000.0 0.45 0.7118 0.9937 2072062 Maybridge1_004971 O/N=C/c1sccc1Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J22 compound treatment 886414.0 282000.0 0.4 936183.0 340000.0 0.47 0.6186 0.9965 1524000 Maybridge1_004972 N#Cc1nccnc1N2CCN(CC2)C(c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J23 mock treatment 954705.0 350000.0 0.5 928513.0 332000.0 0.46 0.6797 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 J24 mock treatment 165124.0 -440000.0 -0.63 152603.0 -444000.0 -0.62 -0.8795 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K01 compound treatment 848765.0 244000.0 0.35 818407.0 222000.0 0.31 0.4646 0.9984 2072063 Maybridge1_004973 CSc1sc(Br)c2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K02 compound treatment 884159.0 279000.0 0.4 889051.0 293000.0 0.41 0.5698 0.9999 1446780 Maybridge1_004974 CC1(C)CCc2cc(ccc2O1)c3cc[nH]n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K03 compound treatment 871266.0 267000.0 0.38 936255.0 340000.0 0.47 0.6034 0.9938 2072064 Maybridge1_004975 CCOC(=O)c1sc(SC)c(c1N)S(=O)(=O)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K04 compound treatment 892791.0 288000.0 0.41 923028.0 327000.0 0.46 0.612 0.9986 2072065 Maybridge1_004976 CSc1sc(c(c1C#N)c2ccccc2)c3ccnc(SCCS(=O)(=O)C)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K05 compound treatment 923319.0 319000.0 0.45 953206.0 357000.0 0.5 0.6725 0.9989 1506894 Maybridge1_004977 Clc1ccc(cc1)S(=O)(=O)CCN2C(=O)CSC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K06 compound treatment 919179.0 314000.0 0.45 904152.0 308000.0 0.43 0.6199 0.9998 2072066 Maybridge1_004978 OC(=O)c1cccnc1SCCS(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K07 compound treatment 956066.0 351000.0 0.5 970909.0 375000.0 0.52 0.7229 0.9997 2072067 Maybridge1_004979 Cc1ccc(cc1)S(=O)(=O)Cc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K08 compound treatment 934254.0 330000.0 0.47 936101.0 340000.0 0.47 0.6666 1.0 2072068 Maybridge1_004980 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K09 compound treatment 889935.0 285000.0 0.41 936693.0 340000.0 0.47 0.6226 0.9969 2072069 Maybridge1_004981 Cn1c(S)nnc1CSc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K10 compound treatment 882550.0 278000.0 0.4 936655.0 340000.0 0.47 0.6152 0.9958 2072070 Maybridge1_004982 Clc1ccc(Sc2nccnc2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K11 compound treatment 932143.0 327000.0 0.47 968369.0 372000.0 0.52 0.6963 0.9985 1412588 Maybridge1_004983 NNC(=O)COc1ccccc1CSc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K12 compound treatment 896380.0 292000.0 0.41 945229.0 349000.0 0.49 0.6375 0.9968 2072071 Maybridge1_004984 C/C(=N\O)/c1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K13 compound treatment 914237.0 310000.0 0.44 970811.0 375000.0 0.52 0.6807 0.9964 2072072 Maybridge1_004985 FC(F)(F)Oc1ccc(cc1)C(=O)/C(=C/Nc2ccccn2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K14 compound treatment 910520.0 306000.0 0.43 934246.0 338000.0 0.47 0.6409 0.9992 1339863 Maybridge1_004986 NC(=S)C1COc2ccccc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K15 compound treatment 966594.0 362000.0 0.51 942230.0 346000.0 0.48 0.7052 0.9995 2072073 Maybridge1_004987 COc1ccc(OC(=O)c2cscc2Sc3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K16 compound treatment 867229.0 263000.0 0.37 912449.0 316000.0 0.44 0.5759 0.9966 1083340 Maybridge1_004988 CSc1nc2ccc(cc2s1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K17 compound treatment 886821.0 282000.0 0.4 930284.0 334000.0 0.47 0.6132 0.9972 1213967 Maybridge1_004989 CCOC(=O)c1cnc2n(C)nc(C)c2c1Oc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K18 compound treatment 792864.0 188000.0 0.27 807538.0 211000.0 0.29 0.3976 0.9988 2072074 Maybridge1_004990 [O-][N+](=O)c1ccc(Sc2ccc(F)cc2)c3nonc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K19 compound treatment 939839.0 335000.0 0.48 942564.0 346000.0 0.48 0.6786 1.0 2072075 Maybridge1_004991 CCOC(=O)c1sc(SCCS(=O)(=O)c2ccccc2)c3C(=O)CC(C)(C)Cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K20 compound treatment 874288.0 270000.0 0.38 940561.0 344000.0 0.48 0.6107 0.9938 2072076 Maybridge1_004992 CNC(=S)NNC(=O)C(CCSC)NC(=O)c1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K21 compound treatment 972375.0 368000.0 0.52 979070.0 383000.0 0.53 0.7473 0.9999 1407614 Maybridge1_004993 COC(=O)c1cccc(CN2C(=O)CSC2=O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K22 compound treatment 917564.0 313000.0 0.44 926277.0 330000.0 0.46 0.6401 0.9999 2072077 Maybridge1_004994 COc1cc(nc2ccc(Br)cc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K23 mock treatment 972983.0 368000.0 0.52 971770.0 376000.0 0.52 0.7407 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 K24 mock treatment 153976.0 -451000.0 -0.64 162284.0 -434000.0 -0.61 -0.8812 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L01 compound treatment 859863.0 255000.0 0.36 818172.0 222000.0 0.31 0.4755 0.9969 2072078 Maybridge1_004995 ONC(=O)c1ncc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L02 compound treatment 887710.0 283000.0 0.4 864805.0 269000.0 0.37 0.5495 0.9994 2072079 Maybridge1_004996 COC(=O)c1ccc(Br)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L03 compound treatment 946562.0 342000.0 0.49 929720.0 334000.0 0.47 0.6727 0.9998 1442715 Maybridge1_004997 CCOC(=O)NC(=O)c1cn(Cc2ccccn2)c(=O)[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L04 compound treatment 943419.0 339000.0 0.48 911130.0 315000.0 0.44 0.6512 0.9989 2072080 Maybridge1_004998 FC(F)(F)c1cccc(c1)n2nc(C#N)c(=O)[nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L05 compound treatment 943309.0 339000.0 0.48 948311.0 352000.0 0.49 0.6877 1.0 1505343 Maybridge1_004999 CC(C)n1cc(C#N)c(=O)n(Cc2ccccc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L06 compound treatment 875691.0 271000.0 0.39 876358.0 280000.0 0.39 0.5488 1.0 2072081 Maybridge1_005000 O=C(Nc1ccccc1)ON=C2CC3CCCC(C2)N3Cc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L07 compound treatment 966158.0 361000.0 0.51 949681.0 353000.0 0.49 0.7121 0.9998 1599249 Maybridge1_005001 CCOC(=O)Cn1c(=O)c(C#N)cn(C(C)C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L08 compound treatment 885058.0 280000.0 0.4 955612.0 359000.0 0.5 0.6364 0.9936 1037742 Maybridge1_005002 NC(=O)CC(NC(=O)OCc1ccccc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L09 compound treatment 952239.0 348000.0 0.49 952896.0 357000.0 0.5 0.7012 1.0 2072082 Maybridge1_005003 CC(C)(C)c1cc2nc(cc(N/N=C/c3ccc(cc3)C(F)(F)F)n2n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L10 compound treatment 907039.0 302000.0 0.43 925230.0 329000.0 0.46 0.6285 0.9995 1727567 Maybridge1_005004 COc1ccc(cc1OC2CCCC2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L11 compound treatment 938184.0 333000.0 0.47 975075.0 379000.0 0.53 0.709 0.9985 2072083 Maybridge1_005005 N#Cc1ccc(C#Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L12 compound treatment 900627.0 296000.0 0.42 945385.0 349000.0 0.49 0.6419 0.9974 1611812 Maybridge1_005006 OC(=O)c1cnc2cc(Cl)cc(Cl)c2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L13 compound treatment 1419161.0 814000.0 1.16 1312437.0 716000.0 1.0 1.5253 0.9973 2072084 Maybridge1_005007 Nc1nc(S)ncc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L14 compound treatment 911552.0 307000.0 0.44 936029.0 340000.0 0.47 0.6437 0.9991 2072085 Maybridge1_005008 OC(=O)c1cnc2ccc(OC(F)(F)F)cc2c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L15 compound treatment 983317.0 379000.0 0.54 989413.0 393000.0 0.55 0.7685 1.0 1110028 Maybridge1_005009 NC(CC(=O)O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L16 compound treatment 854762.0 250000.0 0.36 938978.0 343000.0 0.48 0.5895 0.9894 2072086 Maybridge1_005010 CCOc1cc(ccc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L17 compound treatment 938631.0 334000.0 0.47 962874.0 367000.0 0.51 0.6974 0.9993 2072087 Maybridge1_005011 CC(=O)N1CCc2cc(Br)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L18 compound treatment 948124.0 343000.0 0.49 924125.0 328000.0 0.46 0.6687 0.9995 2072088 Maybridge1_005012 CCCCC#Cc1ccc(o1)C(=O)NNC(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L19 compound treatment 967562.0 363000.0 0.52 963767.0 368000.0 0.51 0.7274 1.0 2072089 Maybridge1_005013 OCCSC1CS(=O)(=O)c2cc(ccc12)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L20 compound treatment 945654.0 341000.0 0.48 916449.0 320000.0 0.45 0.6587 0.9992 2072090 Maybridge1_005014 CC(=O)c1cc2c3ccccc3ccc2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L21 compound treatment 978970.0 374000.0 0.53 929058.0 333000.0 0.46 0.7046 0.9977 2072091 Maybridge1_005015 FC(F)(F)Oc1ccc(NC(=O)Nc2cc(n[nH]2)c3ccco3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L22 compound treatment 950438.0 346000.0 0.49 926446.0 330000.0 0.46 0.6733 0.9995 1173437 Maybridge1_005016 NNC(=O)C1CCN(Cc2cccnc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L23 mock treatment 979023.0 374000.0 0.53 954827.0 359000.0 0.5 0.7301 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 L24 mock treatment 153840.0 -451000.0 -0.64 147972.0 -448000.0 -0.63 -0.8954 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M01 compound treatment 862720.0 258000.0 0.37 822220.0 226000.0 0.32 0.4824 0.9971 2072092 Maybridge1_005017 Cc1nn(Cc2nn[nH]n2)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M02 compound treatment 889288.0 285000.0 0.4 859640.0 263000.0 0.37 0.546 0.9988 2072093 Maybridge1_005018 CC(C)S(=O)(=O)C/C(=N/OCc1c(Cl)cccc1Cl)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M03 compound treatment 940514.0 336000.0 0.48 925781.0 330000.0 0.46 0.6627 0.9998 2072094 Maybridge1_005019 CC1(C)CC(=CC(=S)S1)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M04 compound treatment 907713.0 303000.0 0.43 943880.0 348000.0 0.48 0.6476 0.9983 3177265 Maybridge1_005020 CS(=N)c1ncccc1C(F)(F)F.Cc1cc(C)c(c(C)c1)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M05 compound treatment 957869.0 353000.0 0.5 934264.0 338000.0 0.47 0.6885 0.9995 1393462 Maybridge1_005021 Cc1ccc(cc1)S(=O)(=O)CCN2C(=O)CSC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M06 compound treatment 840081.0 235000.0 0.33 924416.0 328000.0 0.46 0.5604 0.9882 2072096 Maybridge1_005022 COC(=O)c1ccc(CSc2ccc(cn2)C(F)(F)F)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M07 compound treatment 920651.0 316000.0 0.45 971564.0 375000.0 0.52 0.6879 0.9971 1275401 Maybridge1_005023 ONC(=O)CC1Sc2ccccc2NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M08 compound treatment 897188.0 292000.0 0.42 912663.0 316000.0 0.44 0.6062 0.9996 2072097 Maybridge1_005024 [O-][N+](=O)c1cc(ccc1C#N)N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M09 compound treatment 839818.0 235000.0 0.33 893708.0 297000.0 0.41 0.5298 0.9943 2072098 Maybridge1_005025 Fc1c(Cl)cccc1n2sccc2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M10 compound treatment 889755.0 285000.0 0.41 895491.0 299000.0 0.42 0.5818 0.9999 2072099 Maybridge1_005026 Clc1cc(Cl)cc(OS(=O)(=O)c2cccc3nsnc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M11 compound treatment 946823.0 342000.0 0.49 987894.0 392000.0 0.55 0.7303 0.9983 1279337 Maybridge1_005027 CCOC(=O)COc1ccccc1CS(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M12 compound treatment 984711.0 380000.0 0.54 978683.0 382000.0 0.53 0.7593 1.0 1310444 Maybridge1_005028 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2cccc3nsnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M13 compound treatment 952679.0 348000.0 0.49 941827.0 346000.0 0.48 0.6908 0.9999 2072100 Maybridge1_005029 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M14 compound treatment 935458.0 331000.0 0.47 937146.0 341000.0 0.48 0.6688 1.0 2072101 Maybridge1_005030 OC(=O)CSCCOc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M15 compound treatment 914297.0 310000.0 0.44 934977.0 339000.0 0.47 0.6454 0.9994 1360550 Maybridge1_005031 COC(=O)c1ccc2C(=O)CS(=O)(=O)N(C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M16 compound treatment 884660.0 280000.0 0.4 905092.0 309000.0 0.43 0.5861 0.9992 2072102 Maybridge1_005032 NC(=S)c1ccc2nonc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M17 compound treatment 940927.0 336000.0 0.48 924601.0 328000.0 0.46 0.662 0.9998 1983576 Maybridge1_005033 CN(c1ccccc1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M18 compound treatment 889067.0 284000.0 0.4 917808.0 322000.0 0.45 0.6031 0.9987 2072103 Maybridge1_005034 Clc1ccc(cc1)S(=O)(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M19 compound treatment 954875.0 350000.0 0.5 962978.0 367000.0 0.51 0.7138 0.9999 2072104 Maybridge1_005035 CSc1sc(C(=O)N)c2CCc3conc3-c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M20 compound treatment 835777.0 231000.0 0.33 899589.0 303000.0 0.42 0.5316 0.9922 2072105 Maybridge1_005036 FC(F)(F)c1cccc(c1)S(=O)(=O)NCC2COc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M21 compound treatment 960220.0 356000.0 0.51 951281.0 355000.0 0.5 0.7077 0.9999 2072106 Maybridge1_005037 COC(=O)CSCCC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M22 compound treatment 986644.0 382000.0 0.54 1031445.0 435000.0 0.61 0.8133 0.9985 2072107 Maybridge1_005038 COC(=O)c1scc2c(O)cc(nc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M23 mock treatment 963468.0 359000.0 0.51 932107.0 336000.0 0.47 0.692 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 M24 mock treatment 720182.0 115000.0 0.16 591803.0 -4410.0 -0.01 0.1118 0.6802 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N01 compound treatment 883706.0 279000.0 0.4 832713.0 237000.0 0.33 0.5138 0.9958 1088056 Maybridge1_005039 Oc1cc(nc2ccccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N02 compound treatment 886252.0 282000.0 0.4 839827.0 244000.0 0.34 0.5234 0.9967 2072108 Maybridge1_005040 COC(=O)c1ccc(C#Cc2ccccc2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N03 compound treatment 972405.0 368000.0 0.52 894860.0 299000.0 0.42 0.6643 0.9936 2072109 Maybridge1_005041 O=c1[nH]c(=O)n(cc1C#N)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N04 compound treatment 950992.0 346000.0 0.49 935032.0 339000.0 0.47 0.6824 0.9998 2072110 Maybridge1_005042 CCOC(=O)c1c(O)c2cccc(c2nc1SC)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N05 compound treatment 932612.0 328000.0 0.47 947891.0 352000.0 0.49 0.6766 0.9997 2072111 Maybridge1_005043 CSc1nn(cc1/C(=N/O)/N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N06 compound treatment 906487.0 302000.0 0.43 907040.0 311000.0 0.43 0.61 1.0 2072112 Maybridge1_005044 NC(Cc1csc2ccc(Cl)cc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N07 compound treatment 980433.0 376000.0 0.53 982037.0 386000.0 0.54 0.7583 1.0 2072113 Maybridge1_005045 COC(=O)c1sccc1Oc2nccnc2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N08 compound treatment 933045.0 328000.0 0.47 918000.0 322000.0 0.45 0.6475 0.9998 2072114 Maybridge1_005046 CC(=O)c1ccc(C#CCO)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N09 compound treatment 975716.0 371000.0 0.53 998725.0 403000.0 0.56 0.7701 0.9995 2072115 Maybridge1_005047 OCc1nccn1Cc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N10 compound treatment 987985.0 383000.0 0.55 1047957.0 452000.0 0.63 0.8309 0.9974 1913810 Maybridge1_005048 [O-][N+](=O)c1ccc(/C=N/Nc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N11 compound treatment 948245.0 344000.0 0.49 983841.0 388000.0 0.54 0.7277 0.9987 1043306 Maybridge1_005049 Cc1c(Cl)cc(cc1Cl)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N12 compound treatment 924867.0 320000.0 0.46 927906.0 332000.0 0.46 0.6491 1.0 1455622 Maybridge1_005050 Oc1ccnc2cc(Cl)cc(Cl)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N13 compound treatment 923876.0 319000.0 0.45 924929.0 329000.0 0.46 0.6451 1.0 1334136 Maybridge1_005051 Cn1c(=O)c(C#N)cn(c2ccccc2)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N14 compound treatment 893427.0 289000.0 0.41 876414.0 280000.0 0.39 0.5667 0.9997 2072116 Maybridge1_005052 N/C(=N\O)/CCN(Cc1ccco1)S(=O)(=O)c2cccc3nsnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N15 compound treatment 965434.0 361000.0 0.51 966836.0 371000.0 0.52 0.7283 1.0 2072117 Maybridge1_005053 COC(=O)C(C#N)c1ccccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N16 compound treatment 912068.0 307000.0 0.44 911854.0 316000.0 0.44 0.6204 1.0 2072118 Maybridge1_005054 Oc1cc(nc2c(F)cccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N17 compound treatment 941524.0 337000.0 0.48 946637.0 350000.0 0.49 0.6843 0.9999 1382524 Maybridge1_005055 CCOC(=O)c1cncc(C#Cc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N18 compound treatment 959591.0 355000.0 0.5 940900.0 345000.0 0.48 0.6968 0.9997 2072119 Maybridge1_005056 CCCCC#Cc1ccc(o1)C(=O)NNC(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N19 compound treatment 977989.0 373000.0 0.53 953611.0 357000.0 0.5 0.7278 0.9995 1473501 Maybridge1_005057 CC(=O)NC(Cc1ccc(OC(=O)C)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N20 compound treatment 928032.0 323000.0 0.46 942655.0 346000.0 0.48 0.6668 0.9997 2072120 Maybridge1_005058 CN(C)S(=O)(=O)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N21 compound treatment 977741.0 373000.0 0.53 958724.0 363000.0 0.51 0.7326 0.9997 2072121 Maybridge1_005059 N/C(=N\O)/CS(=O)(=O)c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N22 compound treatment 936402.0 332000.0 0.47 952933.0 357000.0 0.5 0.6854 0.9996 2072122 Maybridge1_005060 COc1ccc(CNC(=O)Nc2ccccc2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N23 mock treatment 970909.0 366000.0 0.52 963978.0 368000.0 0.51 0.7309 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 N24 mock treatment 557128.0 -47600.0 -0.07 732485.0 136000.0 0.19 0.0866 0.4291 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O01 compound treatment 870819.0 266000.0 0.38 809522.0 213000.0 0.3 0.478 0.9929 1299316 Maybridge1_005061 NS(=O)(=O)c1ccc(Sc2ccccc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O02 compound treatment 829152.0 224000.0 0.32 793568.0 197000.0 0.28 0.4203 0.9973 2072123 Maybridge1_005062 [O-][N+](=O)c1ccsc1Oc2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O03 compound treatment 899377.0 295000.0 0.42 886357.0 290000.0 0.4 0.5825 0.9998 2072124 Maybridge1_005063 CSC1=CC(=O)CC(C)(C)S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O04 compound treatment 885528.0 281000.0 0.4 855753.0 260000.0 0.36 0.5384 0.9988 1317959 Maybridge1_005064 O=C1NC2(CCCCC2)NC3=C1CCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O05 compound treatment 923266.0 319000.0 0.45 903239.0 307000.0 0.43 0.6231 0.9996 2072125 Maybridge1_005065 CN(C)/C=C/C(=O)c1sc2sc(Br)c(C)c2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O06 compound treatment 903669.0 299000.0 0.43 865876.0 270000.0 0.38 0.5666 0.9981 2072126 Maybridge1_005066 CCOC(=O)c1c[nH]c(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O07 compound treatment 883325.0 279000.0 0.4 860512.0 264000.0 0.37 0.5408 0.9993 2072127 Maybridge1_005067 CC(C)(C)c1cc(ccc1/C=N/O)c2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O08 compound treatment 898624.0 294000.0 0.42 886675.0 290000.0 0.41 0.582 0.9999 2072128 Maybridge1_005068 N#Cc1nccnc1Sc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O09 compound treatment 922798.0 318000.0 0.45 899762.0 304000.0 0.42 0.6192 0.9995 2072129 Maybridge1_005069 CSc1nccc(n1)c2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O10 compound treatment 877369.0 273000.0 0.39 887279.0 291000.0 0.41 0.5612 0.9997 2072130 Maybridge1_005070 CCOC(=O)CNS(=O)(=O)c1cccc2nsnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O11 compound treatment 918052.0 313000.0 0.45 893237.0 297000.0 0.41 0.608 0.9993 2072131 Maybridge1_005071 CN1c2sc(C)c(C)c2C(=C(C(=O)Nc3ccc(OC(F)(F)F)cc3)S1(=O)=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O12 compound treatment 871056.0 266000.0 0.38 848318.0 252000.0 0.35 0.5165 0.9993 1180269 Maybridge1_005072 CSc1ccc(Oc2cccc(F)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O13 compound treatment 929228.0 325000.0 0.46 921583.0 325000.0 0.45 0.6472 1.0 1344419 Maybridge1_005073 CCCS(=O)(=O)c1cc2ccccc2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O14 compound treatment 870073.0 265000.0 0.38 876207.0 280000.0 0.39 0.543 0.9999 2072132 Maybridge1_005074 COc1ccc(cc1OC)/C(=N/O)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O15 compound treatment 951423.0 347000.0 0.49 906486.0 310000.0 0.43 0.6547 0.9979 2072133 Maybridge1_005075 CSc1nc(nc(C2CC2)c1C#N)c3cnccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O16 compound treatment 913026.0 308000.0 0.44 874945.0 279000.0 0.39 0.5849 0.9982 1476668 Maybridge1_005076 CCOC(=O)CC1Sc2ccccc2NC1=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O17 compound treatment 941532.0 337000.0 0.48 905542.0 309000.0 0.43 0.6438 0.9986 2072134 Maybridge1_005077 CS(=O)(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O18 compound treatment 836023.0 231000.0 0.33 834412.0 238000.0 0.33 0.4675 1.0 2072135 Maybridge1_005078 [O-][N+](=O)c1ccc(SCCOC(=O)Nc2ccccc2)c3nonc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O19 compound treatment 924337.0 320000.0 0.45 923204.0 327000.0 0.46 0.6439 1.0 2072136 Maybridge1_005079 CC(=O)c1sc(SCCS(=O)(=O)c2ccccc2)c3C(=O)CC(C)(C)Cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O20 compound treatment 900837.0 296000.0 0.42 908824.0 313000.0 0.44 0.6061 0.9998 1004503 Maybridge1_005080 CCOC(=O)N(c1ccccc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O21 compound treatment 926545.0 322000.0 0.46 929729.0 334000.0 0.47 0.6526 1.0 1983526 Maybridge1_005081 CC(=O)N1CCc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O22 compound treatment 880867.0 276000.0 0.39 873426.0 277000.0 0.39 0.5511 1.0 2072137 Maybridge1_005082 COc1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O23 mock treatment 948133.0 343000.0 0.49 875199.0 279000.0 0.39 0.6205 0.9937 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 O24 mock treatment 490406.0 -114000.0 -0.16 538261.0 -57900.0 -0.08 -0.1721 -0.948 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P01 compound treatment 852700.0 248000.0 0.35 790418.0 194000.0 0.27 0.4409 0.9915 2072138 Maybridge1_005083 COC(=O)CSc1cc(nc2ccccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P02 compound treatment 875049.0 270000.0 0.38 822689.0 226000.0 0.32 0.4952 0.9952 1423734 Maybridge1_005084 NNC(=O)Cc1nc(no1)c2cnccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P03 compound treatment 881889.0 277000.0 0.39 848609.0 252000.0 0.35 0.5277 0.9984 1704264 Maybridge1_005085 Fc1ccc(c(F)c1)n2cc(C#N)c(=O)[nH]c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P04 compound treatment 909611.0 305000.0 0.43 839183.0 243000.0 0.34 0.5462 0.9926 1652651 Maybridge1_005086 N#CC1CN(C1)C(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P05 compound treatment 921470.0 317000.0 0.45 866102.0 270000.0 0.38 0.5847 0.996 1427912 Maybridge1_005087 COc1ccc(cc1OC)C2=NC(C)(C)CO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P06 compound treatment 917355.0 313000.0 0.44 858958.0 263000.0 0.37 0.5735 0.9954 2072139 Maybridge1_005088 COC(=O)c1ccc(cc1Cl)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P07 compound treatment 929639.0 325000.0 0.46 881961.0 286000.0 0.4 0.6086 0.9973 1433980 Maybridge1_005089 CC(C)n1cc(c2nc(C)cs2)c(=O)n(CC(=O)NN)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P08 compound treatment 918506.0 314000.0 0.45 863019.0 267000.0 0.37 0.5787 0.9959 2072140 Maybridge1_005090 Cc1ccc2nc(cc(N3CCNCC3)c2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P09 compound treatment 933225.0 329000.0 0.47 854097.0 258000.0 0.36 0.5847 0.9917 2072141 Maybridge1_005091 Cc1[nH]c2ccccc2c1SCc3nnc(SCC(=O)Nc4cccc(c4)C(F)(F)F)n3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P10 compound treatment 915215.0 311000.0 0.44 856284.0 260000.0 0.36 0.5687 0.9952 2072142 Maybridge1_005092 C/C(=N\O)/c1cccc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P11 compound treatment 916727.0 312000.0 0.44 856923.0 261000.0 0.36 0.5709 0.9951 2072143 Maybridge1_005093 CCOC(=O)c1ccc(OCC#C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P12 compound treatment 900282.0 296000.0 0.42 838316.0 242000.0 0.34 0.536 0.9941 2072144 Maybridge1_005094 CCOC(=O)c1cc2cc(OC(F)(F)F)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P13 compound treatment 941569.0 337000.0 0.48 826887.0 231000.0 0.32 0.5662 0.9812 2072145 Maybridge1_005095 O=S1(=O)CC(Sc2cccs2)c3ccccc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P14 compound treatment 895018.0 290000.0 0.41 852896.0 257000.0 0.36 0.5451 0.9975 1077343 Maybridge1_005096 OC1(CN2CCC1CC2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P15 compound treatment 926704.0 322000.0 0.46 872314.0 276000.0 0.39 0.5961 0.9963 2072146 Maybridge1_005097 CN(CCO)c1cc(nc2ccccc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P16 compound treatment 922270.0 318000.0 0.45 898640.0 302000.0 0.42 0.6176 0.9994 2072147 Maybridge1_005098 Oc1cc(nc2ccc(OC(F)(F)F)cc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P17 compound treatment 943538.0 339000.0 0.48 899687.0 303000.0 0.42 0.64 0.9979 1415776 Maybridge1_005099 CCOC(=O)c1cncc(C#CCO)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P18 compound treatment 926564.0 322000.0 0.46 890444.0 294000.0 0.41 0.6138 0.9985 2072148 Maybridge1_005100 CCCCC#Cc1ccc(o1)C(=O)NNC(=O)Nc2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P19 compound treatment 957024.0 352000.0 0.5 849946.0 254000.0 0.35 0.6045 0.9855 1007764 Maybridge1_005101 [O-][N+](=O)c1ccc2COC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P20 compound treatment 925576.0 321000.0 0.46 891136.0 295000.0 0.41 0.6135 0.9987 2072149 Maybridge1_005102 Fc1ccccc1CN(C(=O)CC#N)C(=O)NC2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P21 compound treatment 912906.0 308000.0 0.44 880899.0 285000.0 0.4 0.5907 0.9988 1716936 Maybridge1_005103 O=C(C1COc2ccccc2O1)N3CCNCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P22 compound treatment 911450.0 307000.0 0.44 872716.0 277000.0 0.39 0.5812 0.9981 1136589 Maybridge1_005104 CCCOc1cc(ccc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P23 mock treatment 885658.0 281000.0 0.4 862820.0 267000.0 0.37 0.5455 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.555 P24 mock treatment 552316.0 -52400.0 -0.07 569288.0 -26900.0 -0.04 -0.0792 -0.9497 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A01 compound treatment 846007.0 258000.0 0.37 784516.0 208000.0 0.29 0.4645 0.9933 1229519 Maybridge1_005105 COc1ccc(cc1OC(C)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A02 compound treatment 837103.0 249000.0 0.35 800093.0 224000.0 0.31 0.4709 0.998 2072150 Maybridge1_005106 O=C(NCc1ccccc1)c2ccc3nonc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A03 compound treatment 853537.0 265000.0 0.38 803414.0 227000.0 0.32 0.4907 0.9962 2072151 Maybridge1_005107 CC(=O)Nc1ccc(Br)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A04 compound treatment 859700.0 272000.0 0.39 814260.0 238000.0 0.33 0.5076 0.9971 1323461 Maybridge1_005108 COc1ccc(Cl)cc1NC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A05 compound treatment 899419.0 311000.0 0.44 845148.0 269000.0 0.37 0.578 0.9966 2072152 Maybridge1_005109 CCCCNC(=O)NCCSCc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A06 compound treatment 909406.0 321000.0 0.46 879575.0 303000.0 0.42 0.622 0.9993 1296767 Maybridge1_005110 Clc1ccc(NC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A07 compound treatment 893344.0 305000.0 0.43 861457.0 285000.0 0.4 0.588 0.999 2072153 Maybridge1_005111 Clc1cc(Cl)cc(NC(=O)NCCSCc2ccco2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A08 compound treatment 894055.0 306000.0 0.43 885983.0 310000.0 0.43 0.6129 1.0 2072154 Maybridge1_005112 Cn1c(SCc2ccc(OC(F)(F)F)cc2)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A09 compound treatment 902015.0 314000.0 0.45 885879.0 309000.0 0.43 0.6208 0.9999 2072155 Maybridge1_005113 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A10 compound treatment 940735.0 353000.0 0.5 883422.0 307000.0 0.43 0.6573 0.9969 1151309 Maybridge1_005114 O=C(NC1Cc2ccccc2C1)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A11 compound treatment 925549.0 337000.0 0.48 907721.0 331000.0 0.46 0.666 0.9998 2072156 Maybridge1_005115 O=C(NCCSCc1ccco1)C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A12 compound treatment 917215.0 329000.0 0.47 895498.0 319000.0 0.45 0.6455 0.9997 1589902 Maybridge1_005116 Brc1ccc(s1)S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A13 compound treatment 926393.0 338000.0 0.48 898190.0 322000.0 0.45 0.6574 0.9994 1661456 Maybridge1_005117 Clc1ccc(NC(=O)c2ccc3snnc3c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A14 compound treatment 931775.0 344000.0 0.49 912094.0 336000.0 0.47 0.6765 0.9998 2072157 Maybridge1_005118 CC(C)(C)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A15 compound treatment 937193.0 349000.0 0.5 918427.0 342000.0 0.48 0.6882 0.9998 2072158 Maybridge1_005119 COc1ccc(cc1OC)c2cc([nH]n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A16 compound treatment 960154.0 372000.0 0.53 894834.0 318000.0 0.44 0.6881 0.9962 1539036 Maybridge1_005120 O=C(CSc1nc2ccccc2o1)NC3Cc4ccccc4C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A17 compound treatment 949345.0 361000.0 0.51 909055.0 333000.0 0.46 0.6912 0.9987 2072159 Maybridge1_005121 Cc1cc2nc(cc(n2n1)C(F)(F)F)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A18 compound treatment 942672.0 354000.0 0.5 885390.0 309000.0 0.43 0.6612 0.997 1365169 Maybridge1_005122 CC(C)(C)OC(=O)NCc1nnc(S)n1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A19 compound treatment 919706.0 332000.0 0.47 895880.0 319000.0 0.45 0.6484 0.9996 2072160 Maybridge1_005123 Fc1cccc(Cl)c1CSCC(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A20 compound treatment 922093.0 334000.0 0.47 886244.0 310000.0 0.43 0.6413 0.9989 2072161 Maybridge1_005124 Fc1cccc2c(cc(nc12)C(F)(F)F)N3CCN(CCOC(=O)C(F)(F)F)CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A21 compound treatment 903408.0 315000.0 0.45 876470.0 300000.0 0.42 0.6129 0.9994 2072162 Maybridge1_005125 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A22 compound treatment 854414.0 266000.0 0.38 847068.0 271000.0 0.38 0.5346 1.0 2072163 Maybridge1_005126 CCOC(=O)c1ccc2nc(cc(N3CCCCC3)c2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A23 mock treatment 838112.0 250000.0 0.36 825897.0 249000.0 0.35 0.4974 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 A24 mock treatment 141005.0 -447000.0 -0.64 145122.0 -431000.0 -0.6 -0.875 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B01 compound treatment 834102.0 246000.0 0.35 786503.0 210000.0 0.29 0.4545 0.9961 2072164 Maybridge1_005127 CSc1nc2ccc(NC(=O)c3ccccc3C(F)(F)F)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B02 compound treatment 840008.0 252000.0 0.36 793203.0 217000.0 0.3 0.467 0.9965 2072165 Maybridge1_005128 CCOC(=O)NNC(=S)Nc1ccccc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B03 compound treatment 918235.0 330000.0 0.47 875730.0 299000.0 0.42 0.6271 0.9983 2072166 Maybridge1_005129 Cc1ccc(cc1Cl)c2ccc(C)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B04 compound treatment 901494.0 313000.0 0.45 878951.0 303000.0 0.42 0.6134 0.9996 2072167 Maybridge1_005130 FC(F)(F)c1cccc(NNC(=S)Nc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B05 compound treatment 935711.0 348000.0 0.49 929926.0 354000.0 0.49 0.6981 1.0 1020737 Maybridge1_005131 COc1cc(Br)c(OC)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B06 compound treatment 902462.0 314000.0 0.45 871991.0 296000.0 0.41 0.6075 0.9992 2072168 Maybridge1_005132 CCOC(=O)N/N=C/c1cc(OC)c(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B07 compound treatment 936237.0 348000.0 0.49 924220.0 348000.0 0.49 0.693 0.9999 2072169 Maybridge1_005133 CCSc1nc2ccccc2nc1SCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B08 compound treatment 885520.0 297000.0 0.42 833080.0 257000.0 0.36 0.5521 0.9966 2072170 Maybridge1_005134 COc1ccccc1NC(=S)NNC(=O)NNC(=S)Nc2ccccc2OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B09 compound treatment 890543.0 302000.0 0.43 932134.0 356000.0 0.5 0.6548 0.9975 2072171 Maybridge1_005135 [O-][N+](=O)c1cccc(c1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B10 compound treatment 903627.0 315000.0 0.45 936120.0 360000.0 0.5 0.6719 0.9984 2072172 Maybridge1_005136 Clc1ccc(/C=N/NC(=S)NC2CC3CC2C=C3)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B11 compound treatment 925382.0 337000.0 0.48 913561.0 337000.0 0.47 0.6716 1.0 2072173 Maybridge1_005137 Cc1ccc(cc1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B12 compound treatment 852001.0 264000.0 0.38 855298.0 279000.0 0.39 0.5403 0.9998 2072174 Maybridge1_005138 CNC(=S)N/N=C/c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B13 compound treatment 912103.0 324000.0 0.46 957678.0 381000.0 0.53 0.7017 0.9974 2072175 Maybridge1_005139 CCc1cc2c(cc1c3csc(Nc4ccccc4Cl)n3)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B14 compound treatment 487682.0 -101000.0 -0.14 488750.0 -87700.0 -0.12 -0.1875 -0.997 2072176 Maybridge1_005140 CNC(=S)N/N=C/c1ccc(OC)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B15 compound treatment 992647.0 404000.0 0.58 996984.0 421000.0 0.59 0.8215 1.0 2072177 Maybridge1_005141 CC(C)c1ccc(/C=N/NC(=O)N\N=C\c2ccc(cc2)C(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B16 compound treatment 886593.0 298000.0 0.42 895806.0 319000.0 0.45 0.615 0.9997 2072178 Maybridge1_005142 COc1cc(cc(OC)c1OC)c2n[nH]c(=S)n2c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B17 compound treatment 983077.0 395000.0 0.56 971515.0 395000.0 0.55 0.7867 1.0 1912581 Maybridge1_005143 COc1ccc(/C=N/NC(=S)N)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B18 compound treatment 884887.0 297000.0 0.42 908200.0 332000.0 0.46 0.6256 0.9989 1046961 Maybridge1_005144 O=C(NNC(=S)NC1CCCCC1)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B19 compound treatment 942884.0 355000.0 0.5 971974.0 396000.0 0.55 0.7468 0.999 1922073 Maybridge1_005145 CCOC(=O)N/N=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B20 compound treatment 894098.0 306000.0 0.44 919494.0 343000.0 0.48 0.646 0.9989 2072179 Maybridge1_005146 Cc1c(C)c(C)c(CSC2=NCN(Cc3cccnc3)CN2)c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B21 compound treatment 916050.0 328000.0 0.47 902445.0 326000.0 0.45 0.6512 0.9999 2072180 Maybridge1_005147 CCOC(=O)N/N=C/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B22 compound treatment 858393.0 270000.0 0.38 873007.0 297000.0 0.41 0.5642 0.9993 2072181 Maybridge1_005148 [O-][N+](=O)c1ccc2C=CS(=O)(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B23 mock treatment 874287.0 286000.0 0.41 846874.0 270000.0 0.38 0.5544 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 B24 mock treatment 20692.0 -568000.0 -0.81 140418.0 -436000.0 -0.61 -1.0006 -0.9903 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C01 compound treatment 763494.0 175000.0 0.25 730518.0 154000.0 0.21 0.3283 0.9973 2072182 Maybridge1_005149 CCCCOc1cc(ccc1OC)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C02 compound treatment 774101.0 186000.0 0.26 757665.0 181000.0 0.25 0.3657 0.9997 2072183 Maybridge1_005150 OC1(CC(=NN1)c2ccc3ccccc3c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C03 compound treatment 829373.0 241000.0 0.34 826350.0 250000.0 0.35 0.489 1.0 2072184 Maybridge1_005151 COC(=O)c1ccc2snnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C04 compound treatment 824628.0 236000.0 0.34 840162.0 264000.0 0.37 0.4979 0.999 1125721 Maybridge1_005152 O=C(NC1Cc2ccccc2C1)Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C05 compound treatment 783936.0 196000.0 0.28 792578.0 216000.0 0.3 0.41 0.9992 2072185 Maybridge1_005153 CC(C)(C)c1ccc(NC(=O)NCCSCc2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C06 compound treatment 822717.0 235000.0 0.33 817756.0 241000.0 0.34 0.4738 1.0 1693944 Maybridge1_005154 Clc1cc(Cl)cc(NC(=O)NC2Cc3ccccc3C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C07 compound treatment 847767.0 260000.0 0.37 815539.0 239000.0 0.33 0.4968 0.9987 2072186 Maybridge1_005155 COc1cc(NC(=O)NCCSCc2ccco2)cc(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C08 compound treatment 837371.0 249000.0 0.35 864882.0 288000.0 0.4 0.5351 0.998 2072187 Maybridge1_005156 Cn1c(SCc2c(Cl)cccc2Cl)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C09 compound treatment 850193.0 262000.0 0.37 877299.0 301000.0 0.42 0.5602 0.9982 2072188 Maybridge1_005157 Clc1ccc(cc1)C(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C10 compound treatment 853990.0 266000.0 0.38 866567.0 290000.0 0.4 0.5534 0.9994 2072189 Maybridge1_005158 CC(C)n1c(nc2cc(ccc12)C(=O)O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C11 compound treatment 857775.0 270000.0 0.38 881495.0 305000.0 0.43 0.572 0.9986 2072190 Maybridge1_005159 COc1ccc(cc1)c2cc(nc(N)n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C12 compound treatment 816739.0 229000.0 0.33 852286.0 276000.0 0.38 0.5019 0.9965 1327971 Maybridge1_005160 CC(C)n1nnc2cc(ccc12)C(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C13 compound treatment 877721.0 290000.0 0.41 897163.0 321000.0 0.45 0.6075 0.9991 2072191 Maybridge1_005161 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C14 compound treatment 774001.0 186000.0 0.26 809169.0 233000.0 0.32 0.4164 0.9948 1942145 Maybridge1_005162 COc1ccc(cc1)c2cc(n3nc(cc3n2)c4ccccc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C15 compound treatment 896737.0 309000.0 0.44 898180.0 322000.0 0.45 0.6276 0.9999 2072192 Maybridge1_005163 Cc1onc(c1C(=O)NCCSCc2ccco2)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C16 compound treatment 841070.0 253000.0 0.36 881116.0 305000.0 0.42 0.5548 0.9965 1549521 Maybridge1_005164 Cc1ccc2[nH]c(SCC(=O)NC3Cc4ccccc4C3)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C17 compound treatment 776173.0 188000.0 0.27 820912.0 245000.0 0.34 0.4302 0.9927 2072193 Maybridge1_005165 FC(F)(F)c1cc(nc2cc(nn12)c3ccccc3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C18 compound treatment 813560.0 225000.0 0.32 855996.0 280000.0 0.39 0.5023 0.9953 2072194 Maybridge1_005166 CC(C)(C)OC(=O)NCc1nnc(S)n1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C19 compound treatment 846156.0 258000.0 0.37 877019.0 301000.0 0.42 0.5559 0.9978 2072195 Maybridge1_005167 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)NCCSCc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C20 compound treatment 837132.0 249000.0 0.35 863791.0 287000.0 0.4 0.5337 0.9981 1065781 Maybridge1_005168 O=C(NC1CCCC1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C21 compound treatment 835958.0 248000.0 0.35 893253.0 317000.0 0.44 0.5616 0.9937 2072196 Maybridge1_005169 CC(C)(C)c1cc2c(CCC2(C)C)c(c1)c3cc(n4nc(cc4n3)c5ccccc5)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C22 compound treatment 807748.0 220000.0 0.31 847901.0 271000.0 0.38 0.4885 0.9954 2072197 Maybridge1_005170 CCOC(=O)c1ccc2nc(cc(N3CCN(Cc4ccccc4)CC3)c2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C23 mock treatment 824585.0 236000.0 0.34 852867.0 276000.0 0.39 0.5103 0.9977 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 C24 mock treatment 144818.0 -443000.0 -0.63 158523.0 -418000.0 -0.58 -0.858 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D01 compound treatment 866761.0 279000.0 0.4 804263.0 228000.0 0.32 0.5048 0.994 2072198 Maybridge1_005171 CSc1nc2ccc(NS(=O)(=O)c3ccc(cc3)[N+](=O)[O-])cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D02 compound treatment 840682.0 252000.0 0.36 796061.0 220000.0 0.31 0.4705 0.9969 2072199 Maybridge1_005172 CCOC(=O)N/N=C/c1ccccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D03 compound treatment 942543.0 354000.0 0.5 906495.0 330000.0 0.46 0.6818 0.999 2072200 Maybridge1_005173 Cc1cc2CN(Cc2cc1C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D04 compound treatment 914522.0 326000.0 0.46 911415.0 335000.0 0.47 0.6585 1.0 2072201 Maybridge1_005174 Clc1ccccc1NC(=S)NNc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D05 compound treatment 904229.0 316000.0 0.45 883284.0 307000.0 0.43 0.6204 0.9997 1245333 Maybridge1_005175 COc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D06 compound treatment 883576.0 295000.0 0.42 888602.0 312000.0 0.44 0.6049 0.9998 2072202 Maybridge1_005176 COc1cc(/C=N/NC(=O)N\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D07 compound treatment 970665.0 382000.0 0.54 928416.0 352000.0 0.49 0.7317 0.9987 2072203 Maybridge1_005177 S(c1ccccc1)c2nc3ccccc3nc2Sc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D08 compound treatment 950326.0 362000.0 0.51 943105.0 367000.0 0.51 0.7258 1.0 2072204 Maybridge1_005178 Clc1cccc(Cl)c1/C=N/NC(=S)NC2CC3CC2C=C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D09 compound treatment 968144.0 380000.0 0.54 940789.0 364000.0 0.51 0.7414 0.9995 2072205 Maybridge1_005179 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D10 compound treatment 977533.0 389000.0 0.55 950120.0 374000.0 0.52 0.7601 0.9995 2072206 Maybridge1_005180 C/C(=N\NC(=O)N/N=C(\C)/c1ccc(cc1)[N+](=O)[O-])/c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D11 compound treatment 983888.0 396000.0 0.56 913043.0 337000.0 0.47 0.7299 0.9959 2072207 Maybridge1_005181 Brc1ccc(cc1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D12 compound treatment 875111.0 287000.0 0.41 894718.0 318000.0 0.44 0.6024 0.9991 2072208 Maybridge1_005182 CNC(=S)N/N=C/c1ccc(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D13 compound treatment 927560.0 339000.0 0.48 932845.0 356000.0 0.5 0.6928 0.9999 2072209 Maybridge1_005183 CCOc1ccc(/C=N/NC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D14 compound treatment 822956.0 235000.0 0.33 805396.0 229000.0 0.32 0.4619 0.9998 2072210 Maybridge1_005184 CNC(=S)N/N=C/c1cc(OC)c(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D15 compound treatment 1002928.0 415000.0 0.59 1019456.0 443000.0 0.62 0.854 0.9997 2072211 Maybridge1_005185 Clc1cccc(Cl)c1/C=N/NC(=O)N\N=C\c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D16 compound treatment 963661.0 375000.0 0.53 1014177.0 438000.0 0.61 0.8093 0.9978 2072212 Maybridge1_005186 COc1ccc(NC(=S)NNC(=O)c2ccncc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D17 compound treatment 1004366.0 416000.0 0.59 1001959.0 426000.0 0.59 0.8382 1.0 2072213 Maybridge1_005187 NC(=S)N/N=C/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D18 compound treatment 915286.0 327000.0 0.47 959840.0 383000.0 0.53 0.7071 0.9976 2072214 Maybridge1_005188 COc1cc(cc(OC)c1OC)C(=O)N/N=C\2/C(=O)Nc3ccc(Br)cc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D19 compound treatment 983970.0 396000.0 0.56 1066982.0 491000.0 0.68 0.8818 0.9953 2072215 Maybridge1_005189 Oc1ccc2ccccc2c1/C=N/NC(=O)N\N=C\c3c(O)ccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D20 compound treatment 978347.0 390000.0 0.55 951328.0 375000.0 0.52 0.7621 0.9996 2072216 Maybridge1_005190 Brc1ccc(CSC2=NCN(Cc3cccnc3)CN2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D21 compound treatment 947521.0 359000.0 0.51 962355.0 386000.0 0.54 0.7419 0.9997 2072217 Maybridge1_005191 CCOC(=O)N/N=C/c1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D22 compound treatment 926811.0 339000.0 0.48 968602.0 392000.0 0.55 0.7273 0.998 2072218 Maybridge1_005192 Nc1ccc2C=CS(=O)(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D23 mock treatment 968231.0 380000.0 0.54 956075.0 380000.0 0.53 0.7566 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 D24 mock treatment 159592.0 -429000.0 -0.61 147574.0 -429000.0 -0.6 -0.8539 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E01 compound treatment 873647.0 285000.0 0.41 805443.0 229000.0 0.32 0.5129 0.993 2072219 Maybridge1_005193 CCCCOc1cc(ccc1OC)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E02 compound treatment 853484.0 265000.0 0.38 840923.0 265000.0 0.37 0.5276 0.9999 2072220 Maybridge1_005194 COC(=O)c1ccc(NC(C)C)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E03 compound treatment 923603.0 335000.0 0.48 926376.0 350000.0 0.49 0.6824 0.9999 1042155 Maybridge1_005195 Clc1cccc(NC(=O)Nc2cccc(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E04 compound treatment 936492.0 348000.0 0.5 947528.0 371000.0 0.52 0.7162 0.9998 2072221 Maybridge1_005196 Cn1c(SCC(=O)N2CCOCC2)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E05 compound treatment 920039.0 332000.0 0.47 906375.0 330000.0 0.46 0.6591 0.9999 2072222 Maybridge1_005197 CCCCc1ccc(NC(=O)NCCSCc2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E06 compound treatment 926446.0 338000.0 0.48 905372.0 329000.0 0.46 0.6646 0.9997 1306801 Maybridge1_005198 COc1cc(NC(=O)NC2Cc3ccccc3C2)cc(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E07 compound treatment 980621.0 392000.0 0.56 950775.0 374000.0 0.52 0.7638 0.9994 2072223 Maybridge1_005199 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(C)(C)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E08 compound treatment 917947.0 330000.0 0.47 987874.0 411000.0 0.57 0.7374 0.995 1576756 Maybridge1_005200 Clc1ccc(cc1)C(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E09 compound treatment 993945.0 406000.0 0.58 1015435.0 439000.0 0.61 0.841 0.9996 2072224 Maybridge1_005201 CCOc1ccccc1NC(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E10 compound treatment 932990.0 345000.0 0.49 1015640.0 439000.0 0.61 0.7799 0.9939 1497192 Maybridge1_005202 CCOc1ccccc1NC(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E11 compound treatment 968435.0 380000.0 0.54 993863.0 417000.0 0.58 0.794 0.9993 2072225 Maybridge1_005203 CC(C)(C)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc4CCCc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E12 compound treatment 930051.0 342000.0 0.49 930096.0 354000.0 0.49 0.6926 1.0 2072226 Maybridge1_005204 FC(F)(F)c1ccc(Cl)c(c1)S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E13 compound treatment 943556.0 355000.0 0.51 957402.0 381000.0 0.53 0.7331 0.9997 1738674 Maybridge1_005205 COC(=O)c1ccc(Cn2nnc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E14 compound treatment 931388.0 343000.0 0.49 974623.0 398000.0 0.56 0.7378 0.9979 1433447 Maybridge1_005206 COc1cccc(SCC(=O)NC2Cc3ccccc3C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E15 compound treatment 1028009.0 440000.0 0.63 1027713.0 451000.0 0.63 0.8873 1.0 2072227 Maybridge1_005207 O=S(=O)(NCCSCc1ccco1)c2cccc3nonc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E16 compound treatment 960230.0 372000.0 0.53 1014368.0 438000.0 0.61 0.806 0.9974 1496993 Maybridge1_005208 O=C(CSc1nnc(SCC(=O)NC2Cc3ccccc3C2)s1)NC4Cc5ccccc5C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E17 compound treatment 988754.0 401000.0 0.57 1022976.0 447000.0 0.62 0.8432 0.999 2072228 Maybridge1_005209 Cc1cc2nc(cc(n2n1)C(F)(F)F)c3ccc4ccccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E18 compound treatment 956104.0 368000.0 0.52 1000122.0 424000.0 0.59 0.7878 0.9982 2072229 Maybridge1_005210 CCCCn1c(S)nnc1CNC(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E19 compound treatment 966498.0 378000.0 0.54 1010432.0 434000.0 0.61 0.8084 0.9983 2072230 Maybridge1_005211 O=S(=O)(NCCSCc1ccco1)c2cc(cs2)S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E20 compound treatment 966429.0 378000.0 0.54 1000123.0 424000.0 0.59 0.7982 0.9989 2072231 Maybridge1_005212 CCOC(=O)C1CCN(CC1)c2cc(nc3c(F)cccc23)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E21 compound treatment 934461.0 346000.0 0.49 984611.0 408000.0 0.57 0.7508 0.9974 2072232 Maybridge1_005213 [O-][N+](=O)c1cccc(c1)c2cc(n3nc(cc3n2)c4ccco4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E22 compound treatment 902630.0 314000.0 0.45 954149.0 378000.0 0.53 0.6887 0.9967 2072233 Maybridge1_005214 OC1(CC(=NN1)c2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E23 mock treatment 899502.0 311000.0 0.44 937165.0 361000.0 0.5 0.6688 0.998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 E24 mock treatment 162085.0 -426000.0 -0.61 159958.0 -416000.0 -0.58 -0.8392 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F01 compound treatment 905041.0 317000.0 0.45 817244.0 241000.0 0.34 0.5561 0.9895 1592040 Maybridge1_005215 CSc1nc2ccc(NS(=O)(=O)c3ccc(NC(=O)C)cc3)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F02 compound treatment 916336.0 328000.0 0.47 878311.0 302000.0 0.42 0.6277 0.9987 2072234 Maybridge1_005216 CCOC(=O)N/N=C/c1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F03 compound treatment 922694.0 334000.0 0.48 920310.0 344000.0 0.48 0.6755 1.0 1040140 Maybridge1_005217 Cc1ccc(CC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F04 compound treatment 961492.0 373000.0 0.53 957013.0 381000.0 0.53 0.7507 1.0 2072235 Maybridge1_005218 [O-][N+](=O)c1cccc(c1)C(=O)CSC2=NCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F05 compound treatment 989555.0 401000.0 0.57 966593.0 390000.0 0.54 0.7884 0.9997 1080225 Maybridge1_005219 COc1ccc(CCNC(=O)c2ccc(Cl)c(Cl)c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F06 compound treatment 964479.0 376000.0 0.54 959429.0 383000.0 0.53 0.7561 1.0 2072236 Maybridge1_005220 CCOC(=O)N/N=C/c1ccc(OC)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F07 compound treatment 1032913.0 445000.0 0.63 974190.0 398000.0 0.55 0.8395 0.9979 1116092 Maybridge1_005221 Oc1c([N+](=O)[O-])c(=O)oc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F08 compound treatment 994744.0 407000.0 0.58 971270.0 395000.0 0.55 0.7982 0.9997 2072237 Maybridge1_005222 Oc1ccc(Cl)cc1/C=N/NC(=O)N\N=C\c2cc(Cl)ccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F09 compound treatment 1052170.0 464000.0 0.66 992241.0 416000.0 0.58 0.8766 0.9979 2072238 Maybridge1_005223 c1nc(sc1c2ccc(cc2)c3ccccc3)c4ccncc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F10 compound treatment 988200.0 400000.0 0.57 911801.0 335000.0 0.47 0.733 0.9953 2072239 Maybridge1_005224 C/C(=N\NC(=O)N/N=C(\C)/c1ccc2ccccc2c1)/c3ccc4ccccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F11 compound treatment 1031699.0 444000.0 0.63 987804.0 411000.0 0.57 0.8517 0.9989 2072240 Maybridge1_005225 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F12 compound treatment 1007731.0 420000.0 0.6 950223.0 374000.0 0.52 0.7905 0.9977 2072241 Maybridge1_005226 CNC(=S)N/N=C/c1cc(Br)cc(Br)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F13 compound treatment 983598.0 395000.0 0.56 997972.0 422000.0 0.59 0.8133 0.9998 2072242 Maybridge1_005227 COc1cccc(/C=N/NC(=S)NCCc2ccccc2)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F14 compound treatment 990082.0 402000.0 0.57 985797.0 409000.0 0.57 0.8079 1.0 1333393 Maybridge1_005228 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F15 compound treatment 972405.0 384000.0 0.55 1042436.0 466000.0 0.65 0.8459 0.9963 2072243 Maybridge1_005229 CC(=O)Nc1ccc(/C=N/NC(=O)N\N=C\c2ccc(NC(=O)C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F16 compound treatment 1009427.0 421000.0 0.6 950756.0 374000.0 0.52 0.7928 0.9977 2072244 Maybridge1_005230 Cc1cccc(C)c1NC(=S)NNC(=O)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F17 compound treatment 1020696.0 432000.0 0.62 1065512.0 489000.0 0.68 0.9173 0.9987 2072245 Maybridge1_005231 O=C(N/N=C/c1ccncc1)N/N=C/c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F18 compound treatment 960306.0 372000.0 0.53 971250.0 395000.0 0.55 0.7636 0.9998 2072246 Maybridge1_005232 Cn1c(S)nnc1c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F19 compound treatment 1008468.0 420000.0 0.6 1023323.0 447000.0 0.62 0.8634 0.9998 2072247 Maybridge1_005233 CCOC(=O)NNC(=S)Nc1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F20 compound treatment 1012349.0 424000.0 0.6 981957.0 406000.0 0.57 0.8265 0.9995 2072248 Maybridge1_005234 CCOC(=O)N/N=C(\C)/c1ccc(OC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F21 compound treatment 1029027.0 441000.0 0.63 1042222.0 466000.0 0.65 0.9027 0.9998 2072249 Maybridge1_005235 CCOC(=O)N/N=C/c1ccccc1OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F22 compound treatment 954374.0 366000.0 0.52 943142.0 367000.0 0.51 0.7299 1.0 1087914 Maybridge1_005236 CC(=O)c1ccc(cc1Cl)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F23 mock treatment 1006629.0 418000.0 0.6 979914.0 404000.0 0.56 0.8187 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 F24 mock treatment 137589.0 -451000.0 -0.64 150539.0 -426000.0 -0.59 -0.8731 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G01 compound treatment 833303.0 245000.0 0.35 792910.0 217000.0 0.3 0.46 0.9974 1043563 Maybridge1_005237 Nc1ccccc1NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G02 compound treatment 855685.0 267000.0 0.38 839417.0 263000.0 0.37 0.5284 0.9998 2072250 Maybridge1_005238 Cc1cc(NC(=O)c2ccc3nonc3c2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G03 compound treatment 886782.0 299000.0 0.42 918638.0 342000.0 0.48 0.6378 0.9983 1536217 Maybridge1_005239 COC(=O)c1sccc1NC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G04 compound treatment 884045.0 296000.0 0.42 923840.0 347000.0 0.48 0.6401 0.9975 2072251 Maybridge1_005240 CC(C)NC(=O)CSc1nnc(c2ccc3ncccc3c2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G05 compound treatment 935323.0 347000.0 0.49 938859.0 362000.0 0.51 0.7065 0.9999 2072252 Maybridge1_005241 COc1ccc(Cl)cc1NC(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G06 compound treatment 897087.0 309000.0 0.44 932505.0 356000.0 0.5 0.6618 0.9981 1639001 Maybridge1_005242 COc1cccc(NC(=O)NC2Cc3ccccc3C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G07 compound treatment 947464.0 359000.0 0.51 927585.0 351000.0 0.49 0.7076 0.9998 2072253 Maybridge1_005243 Fc1ccc(NC(=O)NCCSCc2ccco2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G08 compound treatment 937091.0 349000.0 0.5 940093.0 364000.0 0.51 0.7095 0.9999 1301968 Maybridge1_005244 CC(C)n1nnc2cc(ccc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G09 compound treatment 920467.0 332000.0 0.47 936510.0 360000.0 0.5 0.6893 0.9995 2072254 Maybridge1_005245 Brc1cncc(c1)C(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G10 compound treatment 916544.0 328000.0 0.47 928174.0 352000.0 0.49 0.6771 0.9997 1511751 Maybridge1_005246 O=C(NC1Cc2ccccc2C1)Nc3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G11 compound treatment 952886.0 365000.0 0.52 960881.0 384000.0 0.54 0.7459 0.9999 2072255 Maybridge1_005247 FC(F)(F)c1cc(nc2cc(nn12)c3ccco3)c4ccco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G12 compound treatment 908507.0 320000.0 0.46 961176.0 385000.0 0.54 0.7016 0.9967 1330371 Maybridge1_005248 COc1ccc(Cl)cc1S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G13 compound treatment 932297.0 344000.0 0.49 982547.0 406000.0 0.57 0.7465 0.9973 2072256 Maybridge1_005249 CS(=O)(=NC(=O)c1ccc2nnsc2c1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G14 compound treatment 910804.0 323000.0 0.46 947463.0 371000.0 0.52 0.6903 0.9982 1139185 Maybridge1_005250 COc1ccc(cc1)c2ccnc(SCC(=O)NC3Cc4ccccc4C3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G15 compound treatment 988806.0 401000.0 0.57 973601.0 397000.0 0.55 0.7946 0.9999 2072257 Maybridge1_005251 O=C(NCc1ccc(s1)S(=O)(=O)NCCSCc2ccco2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G16 compound treatment 931208.0 343000.0 0.49 941074.0 365000.0 0.51 0.7046 0.9998 1248175 Maybridge1_005252 Fc1ccc(SCC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G17 compound treatment 962239.0 374000.0 0.53 1022501.0 446000.0 0.62 0.8161 0.997 2072258 Maybridge1_005253 Brc1cncc(c1)C(=O)NNC(=O)c2ccc3ncccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G18 compound treatment 874707.0 287000.0 0.41 907355.0 331000.0 0.46 0.6145 0.9981 2072259 Maybridge1_005254 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4ccc5ccccc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G19 compound treatment 945720.0 358000.0 0.51 1007983.0 432000.0 0.6 0.7851 0.9965 2072260 Maybridge1_005255 Clc1ccc(cc1)S(=O)(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G20 compound treatment 920924.0 333000.0 0.47 993597.0 417000.0 0.58 0.746 0.9947 2072261 Maybridge1_005256 Cn1c(SCC(=O)O)nnc1c2ccc3ncccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G21 compound treatment 911140.0 323000.0 0.46 903323.0 327000.0 0.46 0.6471 1.0 2072262 Maybridge1_005257 [O-][N+](=O)c1cccc(c1)c2cc(n3nc(cc3n2)C4CC4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G22 compound treatment 884069.0 296000.0 0.42 935775.0 359000.0 0.5 0.6519 0.9962 1703981 Maybridge1_005258 OC(=O)c1ccc(Cn2cnc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G23 mock treatment 902521.0 314000.0 0.45 951984.0 376000.0 0.52 0.6865 0.9969 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 G24 mock treatment 151838.0 -436000.0 -0.62 139527.0 -437000.0 -0.61 -0.8696 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H01 compound treatment 871872.0 284000.0 0.4 787043.0 211000.0 0.29 0.493 0.9879 1553141 Maybridge1_005259 CSc1nc2ccc(NC(=O)c3c(C)onc3c4ccccc4)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H02 compound treatment 884709.0 297000.0 0.42 820424.0 244000.0 0.34 0.5388 0.9944 2072263 Maybridge1_005260 CCOC(=O)N/N=C/c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H03 compound treatment 923778.0 336000.0 0.48 922102.0 346000.0 0.48 0.6784 1.0 2072264 Maybridge1_005261 COc1cc2Cc3c(OC)c(OC)c(OC)cc3Cc2c(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H04 compound treatment 883108.0 295000.0 0.42 838957.0 263000.0 0.37 0.5555 0.9977 1912813 Maybridge1_005262 Oc1ccccc1/C=N/c2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H05 compound treatment 972698.0 385000.0 0.55 914504.0 338000.0 0.47 0.7201 0.9973 2072265 Maybridge1_005263 COC(=O)c1ccc(s1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H06 compound treatment 915632.0 327000.0 0.47 866280.0 290000.0 0.4 0.6151 0.9975 2072266 Maybridge1_005264 Clc1ccccc1/C=N/NC(=S)NC2CC3CCC2C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H07 compound treatment 959905.0 372000.0 0.53 923081.0 347000.0 0.48 0.7157 0.999 2072267 Maybridge1_005265 Nc1c([N+](=O)[O-])c(=O)oc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H08 compound treatment 956389.0 368000.0 0.52 940120.0 364000.0 0.51 0.7289 0.9999 2072268 Maybridge1_005266 CCOC(=O)N/N=C/c1cc(Cl)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H09 compound treatment 980511.0 392000.0 0.56 958752.0 382000.0 0.53 0.7716 0.9997 1671736 Maybridge1_005267 CCOC(=O)c1ccc(NC(=S)NN)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H10 compound treatment 972179.0 384000.0 0.55 901770.0 325000.0 0.45 0.707 0.9958 2072269 Maybridge1_005268 O=C(N/N=C/c1cccnc1)N/N=C/c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H11 compound treatment 999025.0 411000.0 0.58 935158.0 359000.0 0.5 0.7669 0.997 2072270 Maybridge1_005269 Cc1ccc(cc1)c2csc(Nc3ccccc3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H12 compound treatment 963672.0 375000.0 0.53 959915.0 384000.0 0.53 0.7558 1.0 2072271 Maybridge1_005270 CNC(=S)N/N=C/c1c(O)ccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H13 compound treatment 939809.0 352000.0 0.5 894636.0 318000.0 0.44 0.6674 0.9982 2072272 Maybridge1_005271 COc1ccc(OC)c(/C=N/NC(=S)NCCc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H14 compound treatment 904747.0 317000.0 0.45 915338.0 339000.0 0.47 0.6526 0.9997 2072273 Maybridge1_005272 COc1ccc(cc1)n2c(SCc3ccc(Br)cc3)nnc2c4ccco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H15 compound treatment 989707.0 402000.0 0.57 968222.0 392000.0 0.55 0.7902 0.9998 2072274 Maybridge1_005273 [O-][N+](=O)c1cccc(/C=N/NC(=O)N\N=C\c2cccc(c2)[N+](=O)[O-])c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H16 compound treatment 910229.0 322000.0 0.46 946778.0 370000.0 0.52 0.6891 0.9982 2072275 Maybridge1_005274 FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H17 compound treatment 973257.0 385000.0 0.55 1000588.0 424000.0 0.59 0.8055 0.9993 2072276 Maybridge1_005275 O=C(N/N=C/c1cccs1)N/N=C/c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H18 compound treatment 929210.0 341000.0 0.48 940771.0 364000.0 0.51 0.7022 0.9997 2072277 Maybridge1_005276 CCCCCCCNC(=S)NNC(=O)c1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H19 compound treatment 986664.0 398000.0 0.57 1003354.0 427000.0 0.6 0.8217 0.9997 2072278 Maybridge1_005277 CCOC(=O)N/N=C/c1ccc(OC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H20 compound treatment 902892.0 315000.0 0.45 873670.0 297000.0 0.41 0.6096 0.9993 2072279 Maybridge1_005278 CCOC(=O)NN=C1CCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H21 compound treatment 1024040.0 436000.0 0.62 1010272.0 434000.0 0.61 0.8661 0.9999 2072280 Maybridge1_005279 CCOC(=O)N/N=C/c1cc(Br)cc(Br)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H22 compound treatment 938011.0 350000.0 0.5 902740.0 326000.0 0.46 0.6736 0.999 2072281 Maybridge1_005280 COC(=O)Cc1csc2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H23 mock treatment 962193.0 374000.0 0.53 942113.0 366000.0 0.51 0.7367 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 H24 mock treatment 160136.0 -428000.0 -0.61 187661.0 -389000.0 -0.54 -0.8138 -0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I01 compound treatment 859930.0 272000.0 0.39 810671.0 234000.0 0.33 0.5043 0.9965 2072282 Maybridge1_005281 Cc1ccc(cc1)S(=O)(=O)OCC2COc3ccccc3O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I02 compound treatment 881575.0 293000.0 0.42 864503.0 288000.0 0.4 0.5791 0.9998 1273865 Maybridge1_005282 O=C(NC1Cc2ccccc2C1)Nc3ccc(OCc4ccccc4)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I03 compound treatment 928727.0 341000.0 0.48 912405.0 336000.0 0.47 0.6738 0.9999 2072283 Maybridge1_005283 COC(=O)c1ccc(CNC(=O)Nc2cccc(SC)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I04 compound treatment 868165.0 280000.0 0.4 920845.0 344000.0 0.48 0.6212 0.9956 1930349 Maybridge1_005284 Cc1cc(C)n2nc(cc2n1)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I05 compound treatment 941762.0 354000.0 0.5 919759.0 343000.0 0.48 0.6941 0.9997 2072284 Maybridge1_005285 Cc1ccc2nc(sc2c1)c3ccc(NS(=O)(=O)c4cccc5nonc45)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I06 compound treatment 912836.0 325000.0 0.46 919538.0 343000.0 0.48 0.6648 0.9998 1585869 Maybridge1_005286 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I07 compound treatment 944701.0 357000.0 0.51 916588.0 340000.0 0.47 0.694 0.9995 2072285 Maybridge1_005287 COc1cccc(NC(=O)NCCSCc2ccco2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I08 compound treatment 915624.0 327000.0 0.47 931352.0 355000.0 0.5 0.6793 0.9995 1175274 Maybridge1_005288 Brc1cncc(c1)C(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I09 compound treatment 855382.0 267000.0 0.38 921741.0 345000.0 0.48 0.6092 0.9931 1343669 Maybridge1_005289 NNC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I10 compound treatment 910435.0 322000.0 0.46 905449.0 329000.0 0.46 0.6485 1.0 1273246 Maybridge1_005290 O=C(NC1Cc2ccccc2C1)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I11 compound treatment 904440.0 316000.0 0.45 912862.0 336000.0 0.47 0.6498 0.9998 2072286 Maybridge1_005291 Nc1nc(cc(n1)C(F)(F)F)c2ccc3CCCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I12 compound treatment 872297.0 284000.0 0.4 930778.0 354000.0 0.49 0.6352 0.995 1126364 Maybridge1_005292 Clc1ccc(s1)S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I13 compound treatment 914869.0 327000.0 0.46 904779.0 328000.0 0.46 0.6523 1.0 2072287 Maybridge1_005293 FC(F)(F)c1cc(n[nH]1)c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I14 compound treatment 911130.0 323000.0 0.46 955821.0 379000.0 0.53 0.6989 0.9975 1287710 Maybridge1_005294 O=C(CSCc1ccccc1)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I15 compound treatment 969028.0 381000.0 0.54 980312.0 404000.0 0.56 0.7813 0.9998 2072288 Maybridge1_005295 COc1ccc(Cl)cc1S(=O)(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I16 compound treatment 933603.0 345000.0 0.49 977179.0 401000.0 0.56 0.7426 0.9979 1566045 Maybridge1_005296 Clc1ccc(SCC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I17 compound treatment 971505.0 383000.0 0.55 1023302.0 447000.0 0.62 0.8262 0.9978 2072289 Maybridge1_005297 FC(F)(F)c1cc(nc2cc(nn12)c3ccccc3)c4ccc5OCOc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I18 compound treatment 931891.0 344000.0 0.49 960068.0 384000.0 0.54 0.724 0.999 2072290 Maybridge1_005298 FC(F)(F)c1cc(N2CCN(Cc3ccccc3)CC2)c4ccccc4n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I19 compound treatment 977464.0 389000.0 0.55 991029.0 415000.0 0.58 0.8003 0.9998 2072291 Maybridge1_005299 COc1ccc(cc1)c2cc(n3nc(C)cc3n2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I20 compound treatment 969156.0 381000.0 0.54 988795.0 412000.0 0.58 0.7898 0.9996 2072292 Maybridge1_005300 Oc1ccc(cc1)n2nnnc2SCc3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I21 compound treatment 915554.0 327000.0 0.47 931164.0 355000.0 0.49 0.679 0.9995 2072293 Maybridge1_005301 CC(C)(C)c1cc2nc(cc(n2n1)C(F)(F)F)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I22 compound treatment 901451.0 313000.0 0.45 933937.0 358000.0 0.5 0.6676 0.9984 1165427 Maybridge1_005302 NNC(=O)CSc1ccnc2cc(Cl)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I23 mock treatment 939748.0 352000.0 0.5 957849.0 381000.0 0.53 0.7297 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 I24 mock treatment 151430.0 -437000.0 -0.62 150728.0 -426000.0 -0.59 -0.859 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J01 compound treatment 878000.0 290000.0 0.41 819060.0 243000.0 0.34 0.5307 0.9952 2072294 Maybridge1_005303 Brc1ccc(s1)S(=O)(=O)Nc2ccc3CS(=O)(=O)Cc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J02 compound treatment 858019.0 270000.0 0.38 800171.0 224000.0 0.31 0.492 0.9947 2072295 Maybridge1_005304 CCOC(=O)N/N=C/c1ccc(OC)c(O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J03 compound treatment 932990.0 345000.0 0.49 912983.0 337000.0 0.47 0.6786 0.9998 2072296 Maybridge1_005305 CCOc1ccc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J04 compound treatment 848333.0 260000.0 0.37 850934.0 275000.0 0.38 0.5323 0.9999 1019747 Maybridge1_005306 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J05 compound treatment 886367.0 298000.0 0.42 878536.0 302000.0 0.42 0.5978 1.0 1467929 Maybridge1_005307 CC(C)(C)c1ccc(s1)C(=O)NC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J06 compound treatment 938631.0 350000.0 0.5 848140.0 272000.0 0.38 0.6204 0.9909 2072297 Maybridge1_005308 COc1ccc(/C=N/NC(=S)NC2CC3CCC2C3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J07 compound treatment 958543.0 370000.0 0.53 912215.0 336000.0 0.47 0.7036 0.9983 1530152 Maybridge1_005309 c1sc(nc1c2ccccc2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J08 compound treatment 928629.0 340000.0 0.48 932512.0 356000.0 0.5 0.6935 0.9999 2072298 Maybridge1_005310 COc1ccc(cc1)c2nc(cs2)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J09 compound treatment 1010864.0 423000.0 0.6 908943.0 333000.0 0.46 0.753 0.9918 1561476 Maybridge1_005311 COc1ccccc1Nc2nnns2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J10 compound treatment 913303.0 325000.0 0.46 888928.0 313000.0 0.44 0.6351 0.9996 2072299 Maybridge1_005312 C/C(=N\NC(=O)N/N=C(\C)/c1ccc(C)cc1)/c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J11 compound treatment 976782.0 389000.0 0.55 885423.0 309000.0 0.43 0.6955 0.9924 2072300 Maybridge1_005313 Fc1ccc(cc1)c2csc(Nc3ccccc3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J12 compound treatment 951937.0 364000.0 0.52 888437.0 312000.0 0.44 0.6735 0.9963 2072301 Maybridge1_005314 CNC(=S)N/N=C/c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J13 compound treatment 951496.0 363000.0 0.52 913339.0 337000.0 0.47 0.6976 0.9989 2072302 Maybridge1_005315 COc1cc(/C=N/NC(=S)NCCc2ccccc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J14 compound treatment 1000101.0 412000.0 0.59 933937.0 358000.0 0.5 0.7668 0.9968 2072303 Maybridge1_005316 COc1cc(cc(OC)c1OC)C(=O)NNC(=S)Nc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J15 compound treatment 958866.0 371000.0 0.53 1005004.0 429000.0 0.6 0.7954 0.998 2072304 Maybridge1_005317 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=O)N\N=C\c2cc(Cl)cc(Cl)c2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J16 compound treatment 953799.0 366000.0 0.52 886253.0 310000.0 0.43 0.6732 0.9958 1083192 Maybridge1_005318 Clc1cccc(NC(=S)NNC(=O)c2ccncc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J17 compound treatment 998281.0 410000.0 0.58 994817.0 418000.0 0.58 0.825 1.0 2072305 Maybridge1_005319 O=C(N/N=C/c1cccc2ccccc12)N/N=C/c3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J18 compound treatment 913034.0 325000.0 0.46 856004.0 280000.0 0.39 0.6024 0.9964 2072306 Maybridge1_005320 CCOC(=O)N/N=C(\C)/c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J19 compound treatment 911149.0 323000.0 0.46 986855.0 410000.0 0.57 0.7295 0.994 2072307 Maybridge1_005321 CCOC(=O)NNC(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J20 compound treatment 921671.0 333000.0 0.47 928478.0 352000.0 0.49 0.6825 0.9998 2072308 Maybridge1_005322 Brc1ccc2NC(=O)/C(=N\NC(=O)c3ccco3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J21 compound treatment 937610.0 349000.0 0.5 952097.0 376000.0 0.52 0.7219 0.9996 2072309 Maybridge1_005323 CCOC(=O)N/N=C/c1cc(Br)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J22 compound treatment 930069.0 342000.0 0.49 917267.0 341000.0 0.48 0.6799 0.9999 1371563 Maybridge1_005324 Cc1c(CC(=S)N2CCOCC2)sc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J23 mock treatment 958277.0 370000.0 0.53 946488.0 370000.0 0.52 0.7371 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 J24 mock treatment 154699.0 -433000.0 -0.62 158764.0 -418000.0 -0.58 -0.8478 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K01 compound treatment 819150.0 231000.0 0.33 789132.0 213000.0 0.3 0.442 0.9987 2072310 Maybridge1_005325 CC(C)Sc1c(Cl)cccc1NC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K02 compound treatment 829837.0 242000.0 0.34 840996.0 265000.0 0.37 0.5039 0.9994 2072311 Maybridge1_005326 CCCCNC(=O)NC1Cc2ccccc2C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K03 compound treatment 887344.0 299000.0 0.43 862695.0 286000.0 0.4 0.5831 0.9995 2072312 Maybridge1_005327 O=C(NCCSCc1ccco1)Nc2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K04 compound treatment 871400.0 283000.0 0.4 867098.0 291000.0 0.41 0.5715 1.0 1232037 Maybridge1_005328 Cc1c(Cl)cccc1NC(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K05 compound treatment 875603.0 287000.0 0.41 919118.0 343000.0 0.48 0.627 0.997 2072313 Maybridge1_005329 Cc1c(Cl)cccc1NC(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K06 compound treatment 849796.0 262000.0 0.37 843989.0 268000.0 0.37 0.5269 1.0 2072314 Maybridge1_005330 FC(F)(F)Oc1ccc(NC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K07 compound treatment 901560.0 313000.0 0.45 919179.0 343000.0 0.48 0.6531 0.9994 2072315 Maybridge1_005331 O=C(NCCSCc1ccco1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K08 compound treatment 892329.0 304000.0 0.43 868640.0 292000.0 0.41 0.594 0.9996 1478124 Maybridge1_005332 Cc1occ(c1C(=O)NC2Cc3ccccc3C2)c4cc(F)ccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K09 compound treatment 877242.0 289000.0 0.41 930777.0 354000.0 0.49 0.6401 0.9958 1022545 Maybridge1_005333 OC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K10 compound treatment 858309.0 270000.0 0.38 878359.0 302000.0 0.42 0.5694 0.9989 1514678 Maybridge1_005334 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K11 compound treatment 864387.0 276000.0 0.39 902833.0 326000.0 0.46 0.5996 0.9973 2072316 Maybridge1_005335 CC(C)(C)c1cc2c(CCC2(C)C)c(c1)c3cc(nc(N)n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K12 compound treatment 873892.0 286000.0 0.41 883713.0 307000.0 0.43 0.5903 0.9996 1395391 Maybridge1_005336 Clc1cccc(c1)S(=O)(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K13 compound treatment 890282.0 302000.0 0.43 875810.0 299000.0 0.42 0.599 0.9999 2072317 Maybridge1_005337 CC(C)(C)c1cc2c(CCC2(C)C)c(c1)c3cc([nH]n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K14 compound treatment 898515.0 310000.0 0.44 891884.0 315000.0 0.44 0.6232 1.0 1326753 Maybridge1_005338 CCn1nnnc1SCC(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K15 compound treatment 917014.0 329000.0 0.47 941707.0 365000.0 0.51 0.6909 0.9991 2072318 Maybridge1_005339 FC(F)(F)c1ccc(Cl)c(c1)S(=O)(=O)NCCSCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K16 compound treatment 921240.0 333000.0 0.47 927790.0 351000.0 0.49 0.6814 0.9999 1589432 Maybridge1_005340 O=C(CSc1cccs1)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K17 compound treatment 929255.0 341000.0 0.49 948786.0 372000.0 0.52 0.7102 0.9994 2072319 Maybridge1_005341 O=C(NCCSCc1ccco1)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K18 compound treatment 926757.0 339000.0 0.48 953903.0 377000.0 0.53 0.7127 0.999 2072320 Maybridge1_005342 Sc1nnc(c2ccc3ncccc3c2)n1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K19 compound treatment 916953.0 329000.0 0.47 937064.0 361000.0 0.5 0.6863 0.9993 2072321 Maybridge1_005343 CC(C)(C)OC(=O)NCC(=O)NNC(=S)NCc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K20 compound treatment 899234.0 311000.0 0.44 923391.0 347000.0 0.48 0.655 0.999 2072322 Maybridge1_005344 CSc1nccc(n1)c2ccc(s2)S(=O)(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K21 compound treatment 955782.0 368000.0 0.52 961866.0 385000.0 0.54 0.7498 0.9999 2072323 Maybridge1_005345 Cc1ccc2[nH]c(SCC(=O)NCCSCc3ccco3)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K22 compound treatment 888920.0 301000.0 0.43 878463.0 302000.0 0.42 0.6003 1.0 2072324 Maybridge1_005346 COc1ccc(cc1)c2ccnc(SCc3cccc(c3)[N+](=O)[O-])n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K23 mock treatment 938677.0 350000.0 0.5 942534.0 366000.0 0.51 0.7135 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 K24 mock treatment 153934.0 -434000.0 -0.62 144001.0 -432000.0 -0.6 -0.8631 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L01 compound treatment 816718.0 229000.0 0.32 792734.0 216000.0 0.3 0.4431 0.9993 2072325 Maybridge1_005347 COC(=O)/C=C(/c1ccccc1)\n2cnc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L02 compound treatment 861356.0 273000.0 0.39 828448.0 252000.0 0.35 0.5232 0.9988 1920895 Maybridge1_005348 CCOC(=O)N/N=C/c1c[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L03 compound treatment 906717.0 319000.0 0.45 877992.0 302000.0 0.42 0.6177 0.9993 1004905 Maybridge1_005349 COc1cccc(NC(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L04 compound treatment 856992.0 269000.0 0.38 863722.0 287000.0 0.4 0.5536 0.9997 1061299 Maybridge1_005350 Clc1ccc(cc1)C(=O)Nc2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L05 compound treatment 894022.0 306000.0 0.43 921822.0 345000.0 0.48 0.6482 0.9987 2072326 Maybridge1_005351 FC(F)(F)c1cc(NC(=O)NC(=O)c2ccc(s2)c3ccc(Cl)cc3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L06 compound treatment 869986.0 282000.0 0.4 803875.0 227000.0 0.32 0.5077 0.9933 2072327 Maybridge1_005352 COc1cc(/C=N/NC(=S)NC2CC3CCC2C3)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L07 compound treatment 862797.0 275000.0 0.39 900208.0 324000.0 0.45 0.5955 0.9974 2072328 Maybridge1_005353 Brc1ccc(cc1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L08 compound treatment 867610.0 279000.0 0.4 889412.0 313000.0 0.44 0.5897 0.9989 2072329 Maybridge1_005354 COc1ccc(cc1)c2nc(cs2)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L09 compound treatment 959811.0 372000.0 0.53 921152.0 345000.0 0.48 0.7137 0.9989 2072330 Maybridge1_005355 c1sc(nc1c2ccc(cc2)c3ccccc3)c4cccnc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L10 compound treatment 668040.0 79800.0 0.11 689861.0 113000.0 0.16 0.1922 0.9867 2072331 Maybridge1_005356 CNC(=S)N/N=C/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L11 compound treatment 908704.0 321000.0 0.46 864364.0 288000.0 0.4 0.6063 0.998 2072332 Maybridge1_005357 Clc1ccccc1Nc2nc(cs2)c3ccc(cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L12 compound treatment 861587.0 273000.0 0.39 898515.0 322000.0 0.45 0.5926 0.9974 2072333 Maybridge1_005358 CNC(=S)N/N=C/c1ccc(OC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L13 compound treatment 921205.0 333000.0 0.47 910066.0 334000.0 0.47 0.6639 1.0 2072334 Maybridge1_005359 CCOc1ccccc1/C=N/NC(=O)N\N=C\c2ccccc2OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L14 compound treatment 908952.0 321000.0 0.46 920188.0 344000.0 0.48 0.6616 0.9997 1125175 Maybridge1_005360 COc1cc(cc(OC)c1OC)c2n[nH]c(=S)n2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L15 compound treatment 939078.0 351000.0 0.5 879544.0 303000.0 0.42 0.6518 0.9966 2072335 Maybridge1_005361 Oc1ccc(Br)cc1/C=N/NC(=O)N\N=C\c2cc(Br)ccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L16 compound treatment 905747.0 318000.0 0.45 909149.0 333000.0 0.46 0.6475 0.9999 1472644 Maybridge1_005362 O=S(=O)(N1CCCCC1)c2ccc(cc2)n3c(n[nH]c3=S)c4ccncc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L17 compound treatment 917790.0 330000.0 0.47 947640.0 371000.0 0.52 0.6975 0.9988 2072336 Maybridge1_005363 COc1cc(/C=N/NC(=O)N\N=C\c2ccc(O)c(OC)c2)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L18 compound treatment 923082.0 335000.0 0.48 906920.0 331000.0 0.46 0.6627 0.9999 1014806 Maybridge1_005364 CC12NC(=O)NC2(C)NC(=O)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L19 compound treatment 960956.0 373000.0 0.53 923716.0 347000.0 0.48 0.7173 0.999 2072337 Maybridge1_005365 CCOC(=O)N/N=C/c1ccc(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L20 compound treatment 913398.0 325000.0 0.46 929846.0 353000.0 0.49 0.6756 0.9995 1090220 Maybridge1_005366 Cc1csc2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L21 compound treatment 946664.0 358000.0 0.51 1006514.0 430000.0 0.6 0.7846 0.9967 2072338 Maybridge1_005367 CCOC(=O)N/N=C/c1ccc(O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L22 compound treatment 885075.0 297000.0 0.42 905654.0 329000.0 0.46 0.6232 0.9991 1250303 Maybridge1_005368 Cc1c(CC(=O)O)sc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L23 mock treatment 918533.0 330000.0 0.47 908003.0 332000.0 0.46 0.6592 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 L24 mock treatment 158450.0 -430000.0 -0.61 138186.0 -438000.0 -0.61 -0.8643 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M01 compound treatment 817915.0 230000.0 0.33 774386.0 198000.0 0.28 0.4262 0.9965 1525913 Maybridge1_005369 CC(C)Sc1c(Cl)cccc1NC(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M02 compound treatment 797903.0 210000.0 0.3 787942.0 212000.0 0.3 0.4195 1.0 1302742 Maybridge1_005370 CC(C)(C)c1ccc(NC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M03 compound treatment 905457.0 317000.0 0.45 882776.0 306000.0 0.43 0.6212 0.9996 2072339 Maybridge1_005371 O=C(NCCSCc1ccco1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M04 compound treatment 818081.0 230000.0 0.33 811795.0 235000.0 0.33 0.4633 1.0 1537203 Maybridge1_005372 Clc1cccc(NC(=O)NC2Cc3ccccc3C2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M05 compound treatment 855314.0 267000.0 0.38 880924.0 305000.0 0.42 0.5689 0.9984 2072340 Maybridge1_005373 Clc1cccc(NC(=O)NCCSCc2ccco2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M06 compound treatment 829217.0 241000.0 0.34 876406.0 300000.0 0.42 0.5382 0.9951 2072341 Maybridge1_005374 Cn1c(SCc2ccc(Cl)cc2)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M07 compound treatment 886423.0 298000.0 0.42 927158.0 351000.0 0.49 0.6458 0.9975 2072342 Maybridge1_005375 FC(F)(F)Oc1ccc(NC(=O)NCCSCc2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M08 compound treatment 877314.0 289000.0 0.41 870434.0 294000.0 0.41 0.5807 1.0 1379425 Maybridge1_005376 Cc1onc(c1C(=O)NC2Cc3ccccc3C2)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M09 compound treatment 860274.0 272000.0 0.39 890921.0 315000.0 0.44 0.5838 0.998 2072343 Maybridge1_005377 Cn1c(S)nnc1c2ccc3ncccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M10 compound treatment 878375.0 290000.0 0.41 867657.0 291000.0 0.41 0.579 1.0 1211239 Maybridge1_005378 O=S(=O)(NC1Cc2ccccc2C1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M11 compound treatment 946729.0 359000.0 0.51 925950.0 350000.0 0.49 0.7052 0.9997 2072344 Maybridge1_005379 FC(F)(F)C(=O)CC(=O)c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M12 compound treatment 877704.0 290000.0 0.41 850837.0 274000.0 0.38 0.5618 0.9993 1477772 Maybridge1_005380 Fc1cccc(Cl)c1CSCC(=O)NC2Cc3ccccc3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M13 compound treatment 918602.0 330000.0 0.47 908765.0 332000.0 0.46 0.66 1.0 2072345 Maybridge1_005381 Nc1nc(cc(n1)C(F)(F)F)c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M14 compound treatment 864720.0 277000.0 0.39 884636.0 308000.0 0.43 0.582 0.999 2072346 Maybridge1_005382 CCCc1cc(O)nc(SCC(=O)NC2Cc3ccccc3C2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M15 compound treatment 941827.0 354000.0 0.5 931783.0 355000.0 0.5 0.7061 1.0 2072347 Maybridge1_005383 Cn1c(SCc2ccccc2)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M16 compound treatment 883859.0 296000.0 0.42 855989.0 280000.0 0.39 0.573 0.9993 1244204 Maybridge1_005384 O=C(Cn1nnc2ccccc12)NC3Cc4ccccc4C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M17 compound treatment 946684.0 358000.0 0.51 938211.0 362000.0 0.5 0.7173 1.0 2072348 Maybridge1_005385 Oc1ccc(cc1)n2nnnc2SCC(=O)NCCSCc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M18 compound treatment 909114.0 321000.0 0.46 887841.0 311000.0 0.43 0.6298 0.9997 2072349 Maybridge1_005386 OCCN1CCN(CC1)c2cc(nc3c(F)cccc23)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M19 compound treatment 930078.0 342000.0 0.49 948852.0 372000.0 0.52 0.7111 0.9995 2072350 Maybridge1_005387 CC(C)(C)OC(=O)NCC(=O)NNC(=S)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M20 compound treatment 868954.0 281000.0 0.4 919722.0 343000.0 0.48 0.6209 0.9959 2072351 Maybridge1_005388 CCOC(=O)c1ccc2nc(cc(N3CCOCC3)c2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M21 compound treatment 987632.0 399000.0 0.57 979378.0 403000.0 0.56 0.7991 1.0 2072352 Maybridge1_005389 O=C(CSc1nnc(SCC(=O)NCCSCc2ccco2)s1)NCCSCc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M22 compound treatment 897404.0 309000.0 0.44 937810.0 361000.0 0.5 0.6673 0.9977 1205842 Maybridge1_005390 COc1ccc(cc1)c2ccnc(SCC(=O)Nc3ccc(cc3)C(C)C)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M23 mock treatment 910641.0 322000.0 0.46 914253.0 338000.0 0.47 0.6574 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 M24 mock treatment 719564.0 131000.0 0.19 676544.0 100000.0 0.14 0.2309 0.9897 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N01 compound treatment 888543.0 300000.0 0.43 819602.0 243000.0 0.34 0.5419 0.9935 1080875 Maybridge1_005391 OC(=O)Cc1noc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N02 compound treatment 885244.0 297000.0 0.42 841113.0 265000.0 0.37 0.5598 0.9977 2072353 Maybridge1_005392 CCOC(=O)N/N=C/c1cccc(O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N03 compound treatment 900056.0 312000.0 0.44 879479.0 303000.0 0.42 0.6125 0.9997 1008357 Maybridge1_005393 CC(=O)Nc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N04 compound treatment 895832.0 308000.0 0.44 851625.0 275000.0 0.38 0.5808 0.9979 2072354 Maybridge1_005394 Cc1ccccc1C(=O)Nc2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N05 compound treatment 920502.0 332000.0 0.47 910580.0 334000.0 0.47 0.6637 1.0 2072355 Maybridge1_005395 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N06 compound treatment 853544.0 265000.0 0.38 882421.0 306000.0 0.43 0.5686 0.9981 2072356 Maybridge1_005396 CCOC(=O)NNC(=S)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N07 compound treatment 902588.0 314000.0 0.45 897097.0 321000.0 0.45 0.6324 1.0 1632182 Maybridge1_005397 Cc1ccc(cc1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N08 compound treatment 843324.0 255000.0 0.36 872139.0 296000.0 0.41 0.5482 0.998 2072357 Maybridge1_005398 COc1ccc(cc1)c2nc(cs2)c3ccc(cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N09 compound treatment 958410.0 370000.0 0.53 937610.0 361000.0 0.5 0.7285 0.9998 2072358 Maybridge1_005399 Fc1ccc(cc1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N10 compound treatment 893501.0 305000.0 0.43 888355.0 312000.0 0.44 0.6146 1.0 2072359 Maybridge1_005400 CNC(=S)N/N=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N11 compound treatment 937674.0 349000.0 0.5 904627.0 328000.0 0.46 0.6751 0.9992 2072360 Maybridge1_005401 [O-][N+](=O)c1cccc(c1)c2csc(Nc3ccccc3Cl)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N12 compound treatment 943705.0 356000.0 0.51 921628.0 345000.0 0.48 0.6979 0.9997 2072361 Maybridge1_005402 CCOc1ccccc1/C=N/NC(=S)NC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N13 compound treatment 891835.0 304000.0 0.43 916894.0 340000.0 0.47 0.6411 0.9989 2072362 Maybridge1_005403 Clc1ccc(/C=N/NC(=O)N\N=C\c2ccc(Cl)c(Cl)c2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N14 compound treatment 869767.0 282000.0 0.4 872139.0 296000.0 0.41 0.5748 0.9999 2072363 Maybridge1_005404 COc1ccc(NC(=S)NNC(=O)c2cc(OC)c(OC)c(OC)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N15 compound treatment 932341.0 344000.0 0.49 937184.0 361000.0 0.5 0.7019 0.9999 2072364 Maybridge1_005405 CCOc1ccccc1/C=N/NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N16 compound treatment 890116.0 302000.0 0.43 901627.0 325000.0 0.45 0.6243 0.9996 1083185 Maybridge1_005406 CNC(=S)NNC(=O)c1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N17 compound treatment 941157.0 353000.0 0.5 965714.0 389000.0 0.54 0.7389 0.9992 2072365 Maybridge1_005407 Oc1cccc(/C=N/NC(=O)N\N=C\c2cccc(O)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N18 compound treatment 944499.0 356000.0 0.51 912069.0 336000.0 0.47 0.6893 0.9992 1550576 Maybridge1_005408 CC1CC(CC(C)(C)C1)N2CNC(=S)NC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N19 compound treatment 957440.0 369000.0 0.53 960077.0 384000.0 0.54 0.7497 1.0 2072366 Maybridge1_005409 CCOC(=O)N/N=C/c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N20 compound treatment 938594.0 350000.0 0.5 934371.0 358000.0 0.5 0.7054 1.0 2072367 Maybridge1_005410 CC(=O)c1sc2ccccc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N21 compound treatment 901123.0 313000.0 0.45 963026.0 387000.0 0.54 0.696 0.9954 1934343 Maybridge1_005411 CCOC(=O)N/N=C/c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N22 compound treatment 950982.0 363000.0 0.52 943409.0 367000.0 0.51 0.7267 1.0 2072368 Maybridge1_005412 CC(=O)c1sc2ccc(Cl)cc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N23 mock treatment 963883.0 376000.0 0.53 964874.0 388000.0 0.54 0.7609 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 N24 mock treatment 749071.0 161000.0 0.23 611816.0 35400.0 0.05 0.1967 0.8404 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O01 compound treatment 864162.0 276000.0 0.39 781242.0 205000.0 0.29 0.4795 0.9878 1627038 Maybridge1_005413 C(N1CCC(CC1)n2nnc3cccnc23)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O02 compound treatment 805793.0 218000.0 0.31 775282.0 199000.0 0.28 0.4149 0.9985 1443998 Maybridge1_005414 CCCCc1ccc(NC(=O)NC2Cc3ccccc3C2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O03 compound treatment 846377.0 258000.0 0.37 833606.0 257000.0 0.36 0.5133 0.9999 2072369 Maybridge1_005415 COC(=O)c1ccc2ncccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O04 compound treatment 835047.0 247000.0 0.35 829523.0 253000.0 0.35 0.4978 1.0 1532931 Maybridge1_005416 Fc1ccc(NC(=O)NC2Cc3ccccc3C2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O05 compound treatment 851512.0 263000.0 0.37 836842.0 260000.0 0.36 0.5216 0.9999 2072370 Maybridge1_005417 Clc1ccc(NC(=O)NCCSCc2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O06 compound treatment 833859.0 246000.0 0.35 851138.0 275000.0 0.38 0.518 0.9989 1469809 Maybridge1_005418 O=C(NC1Cc2ccccc2C1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O07 compound treatment 905194.0 317000.0 0.45 903231.0 327000.0 0.46 0.6411 1.0 2072371 Maybridge1_005419 O=C(NCCSCc1ccco1)Nc2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O08 compound treatment 908867.0 321000.0 0.46 840798.0 264000.0 0.37 0.5832 0.9944 1635085 Maybridge1_005420 O=C(NC1Cc2ccccc2C1)C3CCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O09 compound treatment 852980.0 265000.0 0.38 801254.0 225000.0 0.31 0.488 0.9959 2072372 Maybridge1_005421 FC(F)(F)c1cc(nc2cc(nn12)c3ccccc3)c4ccco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O10 compound treatment 887009.0 299000.0 0.42 863204.0 287000.0 0.4 0.5833 0.9995 1248490 Maybridge1_005422 O=S(=O)(NC1Cc2ccccc2C1)c3cccc4nonc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O11 compound treatment 886228.0 298000.0 0.42 862896.0 286000.0 0.4 0.5822 0.9996 1076165 Maybridge1_005423 Nc1nc(cc(n1)C(F)(F)F)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O12 compound treatment 856892.0 269000.0 0.38 864874.0 288000.0 0.4 0.5547 0.9997 1250785 Maybridge1_005424 CC(C)(C)OC(=O)NCc1nnc(S)n1Cc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O13 compound treatment 890987.0 303000.0 0.43 891547.0 315000.0 0.44 0.6153 0.9999 2072373 Maybridge1_005425 COc1ccc2cc(ccc2c1)c3cc(nc(N)n3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O14 compound treatment 861802.0 274000.0 0.39 882897.0 306000.0 0.43 0.5774 0.9989 1228553 Maybridge1_005426 O=C(CSc1nnnn1c2ccccc2)NC3Cc4ccccc4C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O15 compound treatment 900485.0 312000.0 0.44 906844.0 330000.0 0.46 0.6399 0.9998 2072374 Maybridge1_005427 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3ccc4ncccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O16 compound treatment 828157.0 240000.0 0.34 832850.0 256000.0 0.36 0.4942 0.9997 1220510 Maybridge1_005428 CC(C)(C)OC(=O)NCc1nnc(S)n1C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O17 compound treatment 917494.0 329000.0 0.47 921391.0 345000.0 0.48 0.6714 0.9999 2072375 Maybridge1_005429 COc1ccc(cc1)c2ccnc(SCC(=O)NCCSCc3ccco3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O18 compound treatment 878239.0 290000.0 0.41 868015.0 292000.0 0.41 0.5792 1.0 2072376 Maybridge1_005430 Fc1cccc2c(OC3CCN(Cc4ccccc4)CC3)cc(nc12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O19 compound treatment 911776.0 324000.0 0.46 916927.0 341000.0 0.47 0.6612 0.9999 2072377 Maybridge1_005431 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4nccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O20 compound treatment 841891.0 254000.0 0.36 814604.0 238000.0 0.33 0.49 0.9992 2072378 Maybridge1_005432 CCOC(=O)C1CCN(CC1)c2cc(nc3ccc(cc23)C(=O)OCC)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O21 compound treatment 917215.0 329000.0 0.47 912225.0 336000.0 0.47 0.662 1.0 1467023 Maybridge1_005433 O=C(NCCc1ccccc1)c2ccc3nonc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O22 compound treatment 846503.0 258000.0 0.37 845540.0 269000.0 0.38 0.5252 0.9999 1422747 Maybridge1_005434 COc1ccc(cc1)c2ccnc(SCc3ccccc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O23 mock treatment 925861.0 338000.0 0.48 912249.0 336000.0 0.47 0.6707 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 O24 mock treatment 452509.0 -136000.0 -0.19 271669.0 -305000.0 -0.43 -0.437 -0.9362 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P01 compound treatment 841120.0 253000.0 0.36 773958.0 198000.0 0.28 0.4492 0.9913 2072379 Maybridge1_005435 Cc1ccc(c(c1)[N+](=O)[O-])c2ccc(C)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P02 compound treatment 859119.0 271000.0 0.39 817832.0 241000.0 0.34 0.5105 0.9977 2072380 Maybridge1_005436 COc1cccc(NC(=S)NNc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P03 compound treatment 840879.0 253000.0 0.36 834253.0 258000.0 0.36 0.5084 1.0 1002354 Maybridge1_005437 CC(=O)Nc1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P04 compound treatment 867042.0 279000.0 0.4 844778.0 268000.0 0.37 0.5451 0.9996 1783745 Maybridge1_005438 [O-][N+](=O)c1cccc(c1)C(=O)Nc2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P05 compound treatment 902707.0 315000.0 0.45 843383.0 267000.0 0.37 0.5796 0.9958 2072381 Maybridge1_005439 CCc1nc2ccccc2[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P06 compound treatment 819644.0 231000.0 0.33 791941.0 216000.0 0.3 0.4453 0.999 2072382 Maybridge1_005440 Brc1ccc2NC(=O)/C(=N\NC(=O)N/N=C\3/C(=O)Nc4ccc(Br)cc34)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P07 compound treatment 882292.0 294000.0 0.42 842030.0 266000.0 0.37 0.5577 0.9982 1288646 Maybridge1_005441 Cc1ccc(c2csc(n2)c3ccncc3)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P08 compound treatment 887123.0 299000.0 0.43 848699.0 272000.0 0.38 0.5691 0.9984 2072383 Maybridge1_005442 CCc1cc2c(cc1c3csc(n3)c4ccc(OC)cc4)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P09 compound treatment 885374.0 297000.0 0.42 830836.0 254000.0 0.35 0.5497 0.9962 2072384 Maybridge1_005443 [O-][N+](=O)c1cccc(c1)c2csc(n2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P10 compound treatment 700297.0 112000.0 0.16 654905.0 78500.0 0.11 0.1901 0.9832 2072385 Maybridge1_005444 CNC(=S)N/N=C/c1cc(Br)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P11 compound treatment 841780.0 254000.0 0.36 799952.0 224000.0 0.31 0.4755 0.9974 2072386 Maybridge1_005445 Clc1ccccc1Nc2nc(cs2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P12 compound treatment 881366.0 293000.0 0.42 863096.0 287000.0 0.4 0.5775 0.9998 2072387 Maybridge1_005446 CCOc1ccc(/C=N/NC(=S)NC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P13 compound treatment 856383.0 268000.0 0.38 844475.0 268000.0 0.37 0.534 1.0 2072388 Maybridge1_005447 Clc1ccccc1/C=N/NC(=O)N\N=C\c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P14 compound treatment 886569.0 298000.0 0.42 869688.0 293000.0 0.41 0.5893 0.9998 2072389 Maybridge1_005448 COc1cc(cc(OC)c1OC)C(=O)NNC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P15 compound treatment 864333.0 276000.0 0.39 863090.0 287000.0 0.4 0.5604 1.0 2072390 Maybridge1_005449 CCOc1ccccc1/C=N/Nc2nc(cs2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P16 compound treatment 859004.0 271000.0 0.39 866521.0 290000.0 0.4 0.5584 0.9997 1083198 Maybridge1_005450 C=CCNC(=S)NNC(=O)c1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P17 compound treatment 850089.0 262000.0 0.37 865611.0 289000.0 0.4 0.5486 0.9992 2072391 Maybridge1_005451 CCOc1ccc(/C=N/NC(=O)N\N=C\c2ccc(OCC)c(OC)c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P18 compound treatment 886204.0 298000.0 0.42 860682.0 284000.0 0.4 0.58 0.9994 1713698 Maybridge1_005452 S=C1NCN(Cc2cccnc2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P19 compound treatment 917207.0 329000.0 0.47 885447.0 309000.0 0.43 0.6356 0.9992 2072392 Maybridge1_005453 CCOC(=O)NNC(=S)Nc1c(C)cccc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P20 compound treatment 898506.0 310000.0 0.44 883131.0 307000.0 0.43 0.6145 0.9999 1047435 Maybridge1_005454 O=S1(=O)C=Cc2ccccc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P21 compound treatment 880032.0 292000.0 0.42 877059.0 301000.0 0.42 0.59 1.0 2072393 Maybridge1_005455 CCOC(=O)N/N=C/c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P22 compound treatment 892419.0 304000.0 0.43 868211.0 292000.0 0.41 0.5937 0.9995 2072394 Maybridge1_005456 CC(=O)c1sc2ccc(C)cc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P23 mock treatment 843678.0 255000.0 0.36 838943.0 263000.0 0.37 0.5158 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.556 P24 mock treatment 529556.0 -58600.0 -0.08 385967.0 -190000.0 -0.27 -0.2468 -0.8865 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A01 compound treatment 831888.0 235000.0 0.33 837342.0 236000.0 0.33 0.469 1.0 2072395 Maybridge1_005809 [O-][N+](=O)c1cccc(c1)c2cc(cc(n2)c3ccccc3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A02 compound treatment 818234.0 221000.0 0.31 838083.0 237000.0 0.33 0.456 0.9997 1085165 Maybridge1_005810 NNC(=S)NCCc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A03 compound treatment 838192.0 241000.0 0.34 842361.0 241000.0 0.34 0.4803 0.9999 2072396 Maybridge1_005811 Cc1cccc(C)c1Nc2nnc(S)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A04 compound treatment 832383.0 235000.0 0.33 828782.0 227000.0 0.32 0.461 0.9996 2072397 Maybridge1_005812 S=C(NCc1ccco1)N/N=C/c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A05 compound treatment 836653.0 240000.0 0.34 875667.0 274000.0 0.38 0.5116 0.9983 1250520 Maybridge1_005813 O=C(NC(=S)NCc1cccnc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A06 compound treatment 867167.0 270000.0 0.38 899293.0 298000.0 0.42 0.5655 0.9992 2072398 Maybridge1_005814 CC1=NC2SC=C(N2C(=O)C1)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A07 compound treatment 891390.0 294000.0 0.42 921435.0 320000.0 0.45 0.6117 0.9995 2072399 Maybridge1_005815 CCc1cccc(CC)c1N2C(=O)C(=C(C)C2=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A08 compound treatment 909724.0 313000.0 0.44 920231.0 319000.0 0.44 0.629 1.0 2072400 Maybridge1_005816 Cc1cccc(C)c1n2nnnc2SCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A09 compound treatment 915721.0 319000.0 0.45 897796.0 296000.0 0.41 0.6129 0.9989 1398190 Maybridge1_005817 CCOC(=O)c1ccc(NC(=O)CCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A10 compound treatment 897429.0 301000.0 0.43 913535.0 312000.0 0.44 0.61 1.0 2072401 Maybridge1_005818 Cc1ccc(NC(=S)N2CCCCC2)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A11 compound treatment 887727.0 291000.0 0.41 903070.0 302000.0 0.42 0.5899 1.0 2072402 Maybridge1_005819 COc1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A12 compound treatment 869234.0 272000.0 0.39 907663.0 306000.0 0.43 0.5759 0.9988 2072403 Maybridge1_005820 Oc1ccccc1C(=O)Nc2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A13 compound treatment 912517.0 316000.0 0.45 929523.0 328000.0 0.46 0.641 1.0 1114517 Maybridge1_005821 COc1ccccc1C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A14 compound treatment 908234.0 311000.0 0.44 926891.0 326000.0 0.45 0.6341 0.9999 1484645 Maybridge1_005822 COc1cc(cc(OC)c1OC)C(=O)OCC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A15 compound treatment 902032.0 305000.0 0.43 934896.0 334000.0 0.47 0.6357 0.9994 2072404 Maybridge1_005823 O=c1c2NCCCNc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A16 compound treatment 935377.0 338000.0 0.48 942755.0 341000.0 0.48 0.677 1.0 1666948 Maybridge1_005824 OC(=O)CCC(=O)Nc1cccnc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A17 compound treatment 928933.0 332000.0 0.47 929299.0 328000.0 0.46 0.6573 0.9999 1938917 Maybridge1_005825 CC(=O)Nc1ccc(I)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A18 compound treatment 878927.0 282000.0 0.4 895997.0 295000.0 0.41 0.5741 0.9999 2072405 Maybridge1_005826 COc1ccc(cc1)/C(=C/c2ccccc2OC)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A19 compound treatment 896713.0 300000.0 0.43 930347.0 329000.0 0.46 0.6259 0.9993 2072406 Maybridge1_005827 FC(F)(F)c1cccc(NC(=S)Nc2ccc(NC(=S)Nc3cccc(c3)C(F)(F)F)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A20 compound treatment 865029.0 268000.0 0.38 896097.0 295000.0 0.41 0.5602 0.9993 2072407 Maybridge1_005828 Clc1ccc(Cl)c(NC(=N)SCc2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A21 compound treatment 872314.0 275000.0 0.39 885439.0 284000.0 0.4 0.5571 1.0 2072408 Maybridge1_005829 COCCCNC(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A22 compound treatment 858134.0 261000.0 0.37 867323.0 266000.0 0.37 0.5249 1.0 1421262 Maybridge1_005830 COc1ccc(CCNC(=S)Nc2ccc(Cl)cc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A23 mock treatment 815291.0 218000.0 0.31 813855.0 212000.0 0.3 0.4291 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 A24 mock treatment 148894.0 -448000.0 -0.64 186278.0 -415000.0 -0.58 -0.8599 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B01 compound treatment 923982.0 327000.0 0.47 885585.0 284000.0 0.4 0.6092 0.9968 2072409 Maybridge1_005831 CC(C)(CO)/N=C/c1cc(Cl)cc(Cl)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B02 compound treatment 870025.0 273000.0 0.39 846733.0 245000.0 0.34 0.5166 0.998 1598073 Maybridge1_005832 Cc1onc(c1C(=O)NN2CCCCC2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B03 compound treatment 923656.0 327000.0 0.46 926775.0 325000.0 0.45 0.6495 0.9999 2072410 Maybridge1_005833 CC(=O)Nc1ccc(OCCCCCCOc2ccc(Cl)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B04 compound treatment 933621.0 337000.0 0.48 928693.0 327000.0 0.46 0.6614 0.9997 2072411 Maybridge1_005834 Cc1ccc(Sc2nc(C)c([N+](=O)[O-])c(C)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B05 compound treatment 944470.0 348000.0 0.49 940936.0 340000.0 0.47 0.6844 0.9998 2072412 Maybridge1_005835 CCOC(=O)CSC(=S)Nc1ccc(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B06 compound treatment 928727.0 332000.0 0.47 906231.0 305000.0 0.43 0.6343 0.9986 1704501 Maybridge1_005836 Cc1onc(c1C(=S)N)c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B07 compound treatment 985364.0 388000.0 0.55 973601.0 372000.0 0.52 0.7577 0.9995 2072413 Maybridge1_005837 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B08 compound treatment 958039.0 361000.0 0.51 973710.0 372000.0 0.52 0.7303 1.0 2072414 Maybridge1_005838 CN(C)NC(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B09 compound treatment 991099.0 394000.0 0.56 987773.0 386000.0 0.54 0.7774 0.9998 2072415 Maybridge1_005839 Clc1ccccc1NC(=S)SCCSC(=S)Nc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B10 compound treatment 963651.0 367000.0 0.52 979338.0 378000.0 0.53 0.7415 1.0 1642340 Maybridge1_005840 CCc1onc(c1C(=O)O)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B11 compound treatment 969594.0 373000.0 0.53 970500.0 369000.0 0.51 0.7388 0.9999 2072416 Maybridge1_005841 COc1cc(/C=N/OC(=O)c2ccc(Cl)cc2Cl)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B12 compound treatment 945108.0 348000.0 0.5 959762.0 358000.0 0.5 0.7036 1.0 2072417 Maybridge1_005842 OC(=O)c1coc2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B13 compound treatment 981987.0 385000.0 0.55 1003555.0 402000.0 0.56 0.7838 0.9999 1450030 Maybridge1_005843 OC(=O)c1cnc2sc3ccccc3n2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B14 compound treatment 947203.0 350000.0 0.5 962174.0 361000.0 0.5 0.708 1.0 2072418 Maybridge1_005844 Cc1onc(c1NC(=O)O/N=C/c2ccc(F)cc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B15 compound treatment 966807.0 370000.0 0.53 928415.0 327000.0 0.46 0.6945 0.9975 2072419 Maybridge1_005845 CC(C)(C)CC(C)(C)NC(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B16 compound treatment 1002501.0 406000.0 0.58 1029149.0 428000.0 0.6 0.8297 0.9999 2072420 Maybridge1_005846 Clc1cncc(Cl)c1N/N=C/c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B17 compound treatment 1005370.0 408000.0 0.58 1021742.0 420000.0 0.59 0.8253 1.0 2072421 Maybridge1_005847 ClC(Cl)(Cl)C(=O)NCCOC(=O)C(Cl)(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B18 compound treatment 959371.0 362000.0 0.52 906512.0 305000.0 0.43 0.6654 0.9955 2072422 Maybridge1_005848 FC(F)(F)c1ccc(NC(=O)O/N=C/c2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B19 compound treatment 1002188.0 405000.0 0.58 996386.0 395000.0 0.55 0.7971 0.9997 2072423 Maybridge1_005849 FC(F)(F)c1cc(nc(S)c1C#N)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B20 compound treatment 931532.0 335000.0 0.48 945025.0 344000.0 0.48 0.6754 1.0 1421916 Maybridge1_005850 Cc1nccc(O)c1OCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B21 compound treatment 965086.0 368000.0 0.52 956947.0 356000.0 0.5 0.7209 0.9996 1003776 Maybridge1_005851 CCOC(=O)C1=C(C)NC(=O)NC1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B22 compound treatment 897070.0 300000.0 0.43 935394.0 334000.0 0.47 0.6312 0.999 2072424 Maybridge1_005852 N/C(=N\OC(=O)C(Cl)Cl)/c1ccc(OCc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B23 mock treatment 879359.0 282000.0 0.4 921108.0 320000.0 0.45 0.5993 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 B24 mock treatment 140313.0 -457000.0 -0.65 147239.0 -454000.0 -0.63 -0.907 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C01 compound treatment 757754.0 161000.0 0.23 756952.0 156000.0 0.22 0.3152 0.9997 2072425 Maybridge1_005853 O=C/1OC(=N\C1=C\c2cccs2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C02 compound treatment 726237.0 129000.0 0.18 768935.0 168000.0 0.23 0.2953 0.993 2072426 Maybridge1_005854 Clc1ccc(/C=N/NC(=S)NCCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C03 compound treatment 791389.0 194000.0 0.28 857349.0 256000.0 0.36 0.448 0.992 1083084 Maybridge1_005855 O=C(NC(=S)N1CCOCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C04 compound treatment 779664.0 183000.0 0.26 793836.0 192000.0 0.27 0.3736 0.9999 2072427 Maybridge1_005856 Clc1ccc(/C=N/NC(=S)NCC2CCCO2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C05 compound treatment 800396.0 203000.0 0.29 828882.0 228000.0 0.32 0.429 0.9989 2072428 Maybridge1_005857 CC1=C(C)C(=O)N(C1=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C06 compound treatment 802813.0 206000.0 0.29 859968.0 259000.0 0.36 0.4621 0.9946 2072429 Maybridge1_005858 Cc1ccc(cc1)S(=O)(=O)NNC(=S)NCCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C07 compound treatment 828441.0 232000.0 0.33 891069.0 290000.0 0.4 0.5185 0.9948 2072430 Maybridge1_005859 O=C/1Nc2ccccc2S\C1=C\c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C08 compound treatment 818227.0 221000.0 0.31 892725.0 291000.0 0.41 0.5099 0.992 1004237 Maybridge1_005860 Clc1ccc(cc1)c2cc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C09 compound treatment 839717.0 243000.0 0.35 921961.0 321000.0 0.45 0.5603 0.9918 1190809 Maybridge1_005861 CCOC(=O)c1ccc(cc1)N2C(=O)CCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C10 compound treatment 842729.0 246000.0 0.35 838681.0 237000.0 0.33 0.4812 0.9996 2072431 Maybridge1_005862 CCCOc1ccccc1/C=N/NC(=S)Nc2cccc(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C11 compound treatment 707465.0 111000.0 0.16 743156.0 142000.0 0.2 0.251 0.9935 1077735 Maybridge1_005863 [O-][N+](=O)c1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C12 compound treatment 815704.0 219000.0 0.31 897613.0 296000.0 0.41 0.5121 0.9902 1587025 Maybridge1_005864 Nc1ccc(NC(=O)c2ccccc2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C13 compound treatment 797343.0 200000.0 0.29 917557.0 316000.0 0.44 0.5133 0.9777 2072432 Maybridge1_005865 Cc1c(C)c2nsnc2cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C14 compound treatment 825664.0 229000.0 0.33 867946.0 267000.0 0.37 0.4929 0.9978 2072433 Maybridge1_005866 Cc1cc(ccc1[N+](=O)[O-])C(=O)OCC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C15 compound treatment 887531.0 291000.0 0.41 967000.0 366000.0 0.51 0.6528 0.9946 1006765 Maybridge1_005867 NC(=O)c1ccccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C16 compound treatment 833958.0 237000.0 0.34 896839.0 295000.0 0.41 0.5297 0.995 2072434 Maybridge1_005868 CC1(CO)CS/C(=N/c2ccc(F)cc2)/N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C17 compound treatment 820598.0 224000.0 0.32 920767.0 319000.0 0.45 0.5399 0.9864 2072435 Maybridge1_005869 FC(F)(F)c1ccc2nccnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C18 compound treatment 799144.0 202000.0 0.29 843148.0 242000.0 0.34 0.4418 0.9969 1481839 Maybridge1_005870 Nc1cc(NC(=O)c2ccccc2O)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C19 compound treatment 842353.0 245000.0 0.35 925833.0 324000.0 0.45 0.5668 0.9918 2072436 Maybridge1_005871 OC(=O)CCNC(=S)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C20 compound treatment 770475.0 174000.0 0.25 902428.0 301000.0 0.42 0.4714 0.9679 2072437 Maybridge1_005872 Cc1cccc(C)c1NC(=N)NC(=N)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C21 compound treatment 866909.0 270000.0 0.38 888233.0 287000.0 0.4 0.5544 0.9998 1271117 Maybridge1_005873 CCOC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C22 compound treatment 823693.0 227000.0 0.32 854663.0 253000.0 0.35 0.4778 0.999 1735016 Maybridge1_005874 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C23 mock treatment 839110.0 242000.0 0.34 844467.0 243000.0 0.34 0.4833 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 C24 mock treatment 155673.0 -441000.0 -0.63 155799.0 -446000.0 -0.62 -0.8831 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D01 compound treatment 852362.0 255000.0 0.36 828349.0 227000.0 0.32 0.4807 0.9976 2072438 Maybridge1_005875 CC[n+]1c(C)csc1Nc2ccc(C)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D02 compound treatment 868765.0 272000.0 0.39 866893.0 266000.0 0.37 0.5352 0.9998 1023658 Maybridge1_005876 OC(=O)CSc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D03 compound treatment 938815.0 342000.0 0.49 958029.0 357000.0 0.5 0.6955 0.9999 2072439 Maybridge1_005877 CCOC(=O)C(C)Oc1ccc(NC(=O)C(Cl)Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D04 compound treatment 892659.0 296000.0 0.42 943327.0 342000.0 0.48 0.6346 0.998 1491174 Maybridge1_005878 CN(C(=O)N(C)C(=O)c1c(C)onc1c2c(F)cccc2Cl)C(=O)c3c(C)onc3c4c(F)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D05 compound treatment 943243.0 346000.0 0.49 1003510.0 402000.0 0.56 0.7448 0.9979 2072440 Maybridge1_005879 CCOC(=O)CSC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D06 compound treatment 904363.0 307000.0 0.44 848668.0 247000.0 0.34 0.553 0.9931 1326646 Maybridge1_005880 Cc1onc(c1C(=S)N)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D07 compound treatment 968232.0 371000.0 0.53 958240.0 357000.0 0.5 0.7253 0.9996 1029766 Maybridge1_005881 Cc1c(Cc2ccccc2)c(=O)oc3cc(O)ccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D08 compound treatment 973316.0 376000.0 0.54 950186.0 349000.0 0.49 0.7225 0.9989 2072441 Maybridge1_005882 Clc1cccc(Cl)c1/C=C/2\C(=O)ON=C2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D09 compound treatment 1012422.0 415000.0 0.59 998911.0 398000.0 0.55 0.8099 0.9995 1275847 Maybridge1_005883 Clc1ccc(NC(=S)CCC(=S)Nc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D10 compound treatment 995041.0 398000.0 0.57 1025085.0 424000.0 0.59 0.8182 0.9998 1317532 Maybridge1_005884 CC(C)(C)c1cc(nn1c2ccccc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D11 compound treatment 950990.0 354000.0 0.5 1019414.0 418000.0 0.58 0.7683 0.9973 1536772 Maybridge1_005885 COc1cccc(Cl)c1c2nc(N)nc(N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D12 compound treatment 934878.0 338000.0 0.48 946238.0 345000.0 0.48 0.6799 1.0 2072442 Maybridge1_005886 Clc1ccc(Sc2c(Cl)cncc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D13 compound treatment 940937.0 344000.0 0.49 992239.0 391000.0 0.55 0.7314 0.9985 2072443 Maybridge1_005887 NNC(=O)COc1ccc(OC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D14 compound treatment 958790.0 362000.0 0.51 947296.0 346000.0 0.48 0.705 0.9995 2072444 Maybridge1_005888 CN(C)c1ccc(/C=N/OC(=O)Nc2c(C)onc2c3c(Cl)cccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D15 compound treatment 1036895.0 440000.0 0.63 1039262.0 438000.0 0.61 0.8743 0.9999 2072445 Maybridge1_005889 Cc1cc(C)c(C#N)c(OC(=O)c2ccccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D16 compound treatment 963354.0 366000.0 0.52 1022209.0 421000.0 0.59 0.7835 0.9982 2072446 Maybridge1_005890 Clc1cncc(Cl)c1N/N=C/C2CC3CC2C=C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D17 compound treatment 1018713.0 422000.0 0.6 1003939.0 403000.0 0.56 0.8211 0.9995 1274198 Maybridge1_005891 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D18 compound treatment 972454.0 376000.0 0.53 906154.0 305000.0 0.43 0.6782 0.9936 2072447 Maybridge1_005892 FC(F)(F)c1ccc(NC(=O)O/N=C/c2c(Cl)cccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D19 compound treatment 1016130.0 419000.0 0.6 982857.0 381000.0 0.53 0.7978 0.9984 1942919 Maybridge1_005893 Cc1cc(C)c(C#N)c(SCC#C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D20 compound treatment 965849.0 369000.0 0.52 1012911.0 412000.0 0.57 0.7768 0.999 1656205 Maybridge1_005894 CCOC(=O)Cn1cc(Cl)c(=O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D21 compound treatment 1001149.0 404000.0 0.57 1038446.0 437000.0 0.61 0.8375 0.9996 1270254 Maybridge1_005895 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D22 compound treatment 959181.0 362000.0 0.52 989829.0 388000.0 0.54 0.7474 0.9997 1520983 Maybridge1_005896 Clc1ccc(COc2ccc(cc2)c3noc(n3)C4CC4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D23 mock treatment 974869.0 378000.0 0.54 996993.0 396000.0 0.55 0.7702 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 D24 mock treatment 158041.0 -439000.0 -0.62 149135.0 -452000.0 -0.63 -0.8873 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E01 compound treatment 853228.0 256000.0 0.36 860306.0 259000.0 0.36 0.5131 1.0 2072448 Maybridge1_005897 C1Oc2ccc(/N=C/c3cccs3)cc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E02 compound treatment 841172.0 244000.0 0.35 887555.0 286000.0 0.4 0.5278 0.9976 2072449 Maybridge1_005898 S=C(NCCc1ccccc1)N/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E03 compound treatment 920828.0 324000.0 0.46 997601.0 396000.0 0.55 0.7165 0.9959 1085188 Maybridge1_005899 CCOC(=O)NC(=S)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E04 compound treatment 910606.0 314000.0 0.45 968328.0 367000.0 0.51 0.6773 0.9977 2072450 Maybridge1_005900 S=C(NCC1CCCO1)N/N=C/c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E05 compound treatment 944719.0 348000.0 0.49 934543.0 333000.0 0.46 0.6783 0.9995 2072451 Maybridge1_005901 Cc1ccccc1SC(CC(=O)c2ccc3ccccc3c2)c4ccc(Cl)c(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E06 compound treatment 939928.0 343000.0 0.49 973532.0 372000.0 0.52 0.7119 0.9995 2072452 Maybridge1_005902 Cc1ccc(cc1)S(=O)(=O)NNC(=S)Nc2cccc(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E07 compound treatment 940506.0 344000.0 0.49 946601.0 345000.0 0.48 0.686 1.0 2072453 Maybridge1_005903 Clc1ccc(/C=C\2/Sc3ccccc3NC2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E08 compound treatment 964556.0 368000.0 0.52 976773.0 375000.0 0.52 0.7399 1.0 1052672 Maybridge1_005904 c1c([nH]c2ccccc12)c3ccc4ccccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E09 compound treatment 1005790.0 409000.0 0.58 1005381.0 404000.0 0.56 0.8096 0.9999 1022340 Maybridge1_005905 CC(=O)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E10 compound treatment 940204.0 343000.0 0.49 1018155.0 417000.0 0.58 0.7562 0.9962 2072454 Maybridge1_005906 CCCOc1ccccc1/C=N/NC(=S)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E11 compound treatment 979867.0 383000.0 0.54 1026467.0 425000.0 0.59 0.8043 0.9991 2072455 Maybridge1_005907 Fc1cc2nsnc2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E12 compound treatment 960173.0 363000.0 0.52 965618.0 364000.0 0.51 0.7245 1.0 1296646 Maybridge1_005908 Fc1ccccc1Nc2ccccc2C(=O)OCC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E13 compound treatment 930741.0 334000.0 0.47 1026937.0 426000.0 0.59 0.7554 0.9939 1722583 Maybridge1_005909 NNC(=O)c1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E14 compound treatment 915008.0 318000.0 0.45 1037050.0 436000.0 0.61 0.7495 0.9894 2072456 Maybridge1_005910 Cc1onc(c1C(=O)OCC(=O)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E15 compound treatment 1006976.0 410000.0 0.58 1054758.0 453000.0 0.63 0.8595 0.9992 1592470 Maybridge1_005911 CC(C)(Oc1ccc(Cl)cc1)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E16 compound treatment 966613.0 370000.0 0.53 1042146.0 441000.0 0.61 0.8064 0.997 2072457 Maybridge1_005912 COc1ccc(/N=C\2/NC(C)(CO)CS2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E17 compound treatment 993273.0 396000.0 0.56 1067326.0 466000.0 0.65 0.8581 0.9975 2072458 Maybridge1_005913 Cc1cc2nsnc2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E18 compound treatment 950597.0 354000.0 0.5 1016740.0 415000.0 0.58 0.7653 0.9975 2072459 Maybridge1_005914 COc1c(Br)cc(cc1Br)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E19 compound treatment 938978.0 342000.0 0.49 1022784.0 421000.0 0.59 0.7595 0.9956 2072460 Maybridge1_005915 CSC(=N)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E20 compound treatment 969700.0 373000.0 0.53 1037585.0 436000.0 0.61 0.805 0.9976 2072461 Maybridge1_005916 Cc1ccc(NC(=N)NC(=N)N)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E21 compound treatment 990510.0 394000.0 0.56 1070522.0 469000.0 0.65 0.8584 0.997 2072462 Maybridge1_005917 COc1ccc(NC(=S)N/N=C/c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E22 compound treatment 930627.0 334000.0 0.47 1014998.0 414000.0 0.58 0.7435 0.9953 1568412 Maybridge1_005918 COc1ccc(CCNC(=S)Nc2ccc(Cl)cc2C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E23 mock treatment 987157.0 390000.0 0.55 975844.0 374000.0 0.52 0.7617 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 E24 mock treatment 136960.0 -460000.0 -0.65 147008.0 -454000.0 -0.63 -0.9106 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F01 compound treatment 860366.0 263000.0 0.37 838739.0 237000.0 0.33 0.499 0.9981 1047734 Maybridge1_005919 [O-][N+](=O)c1ccc(OCCCOc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F02 compound treatment 890371.0 293000.0 0.42 892280.0 291000.0 0.41 0.582 0.9999 2072463 Maybridge1_005920 Cc1onc(c1C(=O)NNc2ccccc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F03 compound treatment 946442.0 350000.0 0.5 968970.0 368000.0 0.51 0.714 0.9999 2072464 Maybridge1_005921 CCOC(=O)C(C)Oc1ccc(NC(=O)C(Cl)(Cl)Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F04 compound treatment 966613.0 370000.0 0.53 969827.0 368000.0 0.51 0.7351 0.9999 2072465 Maybridge1_005922 NC(=S)N/N=C/c1ccc(s1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F05 compound treatment 1006977.0 410000.0 0.58 1027549.0 426000.0 0.59 0.8326 1.0 2072466 Maybridge1_005923 CCOC(=O)c1ccc(OCc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F06 compound treatment 935611.0 339000.0 0.48 951581.0 350000.0 0.49 0.6859 1.0 1017491 Maybridge1_005924 OC(=O)c1cc(O)nc2ccc(Br)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F07 compound treatment 1031478.0 435000.0 0.62 987804.0 386000.0 0.54 0.8181 0.9977 2072467 Maybridge1_005925 Cc1nc(SCC(=O)c2ccc(Cl)cc2)nc(O)c1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F08 compound treatment 987157.0 390000.0 0.55 914574.0 313000.0 0.44 0.7013 0.993 2072468 Maybridge1_005926 Fc1cccc(Cl)c1N/N=C\2/C(=O)ON=C2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F09 compound treatment 1060327.0 463000.0 0.66 1003157.0 402000.0 0.56 0.8622 0.9967 2072469 Maybridge1_005927 FC(F)(F)c1cc(NC(=S)SCCSC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F10 compound treatment 1030356.0 433000.0 0.62 978673.0 377000.0 0.53 0.8079 0.9969 2072470 Maybridge1_005928 Cc1onc(c1C(=O)Oc2c(Cl)cncc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F11 compound treatment 1011533.0 415000.0 0.59 982997.0 382000.0 0.53 0.7933 0.9987 2072471 Maybridge1_005929 Cc1ccc(OC(=O)/C=C/c2cccs2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F12 compound treatment 972182.0 375000.0 0.53 975085.0 374000.0 0.52 0.7459 0.9999 2072472 Maybridge1_005930 CN(C)C(=O)Oc1noc2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F13 compound treatment 964537.0 368000.0 0.52 950214.0 349000.0 0.49 0.7137 0.9994 2072473 Maybridge1_005931 S=C1NC(C=C(N1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F14 compound treatment 957194.0 360000.0 0.51 995821.0 394000.0 0.55 0.7513 0.9994 2072474 Maybridge1_005932 Cc1onc(c1NC(=O)O/N=C/c2ccccc2[N+](=O)[O-])c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F15 compound treatment 1014923.0 418000.0 0.59 1066994.0 466000.0 0.65 0.8795 0.999 1663929 Maybridge1_005933 Cc1cc(C)c(C#N)c(OC(=O)c2c(F)cccc2F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F16 compound treatment 996788.0 400000.0 0.57 993853.0 392000.0 0.55 0.7891 0.9998 2072475 Maybridge1_005934 CC(=N/N=C/1\SCC(=N1)c2ccc(Cl)cc2)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F17 compound treatment 1007784.0 411000.0 0.58 1060036.0 459000.0 0.64 0.8655 0.999 1393277 Maybridge1_005935 CSc1cccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F18 compound treatment 968999.0 372000.0 0.53 960755.0 359000.0 0.5 0.7286 0.9996 1574754 Maybridge1_005936 Cc1nccc(O)c1OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F19 compound treatment 2574108.0 1980000.0 2.81 2835900.0 2230000.0 3.12 4.1919 0.9987 2072476 Maybridge1_005937 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F20 compound treatment 1011828.0 415000.0 0.59 1006901.0 406000.0 0.57 0.8171 0.9998 1261435 Maybridge1_005938 NNC(=O)Cn1cc(Cl)c(=O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F21 compound treatment 1017962.0 421000.0 0.6 1060164.0 459000.0 0.64 0.8758 0.9994 1237977 Maybridge1_005939 CCOC(=O)C1=C(C)NC(=O)NC1c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F22 compound treatment 983759.0 387000.0 0.55 975036.0 374000.0 0.52 0.7575 0.9996 1652480 Maybridge1_005940 CC(=O)Nc1cccc(c1)c2cc(no2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F23 mock treatment 1008815.0 412000.0 0.59 1013059.0 412000.0 0.57 0.8202 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 F24 mock treatment 146872.0 -450000.0 -0.64 150749.0 -451000.0 -0.63 -0.897 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G01 compound treatment 839760.0 243000.0 0.35 822976.0 222000.0 0.31 0.4627 0.9985 2072477 Maybridge1_005941 CCOc1ccc(/N=C/c2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G02 compound treatment 811741.0 215000.0 0.31 873465.0 272000.0 0.38 0.4843 0.9942 2072478 Maybridge1_005942 CC(=O)CCCNc1nc(cs1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G03 compound treatment 898148.0 301000.0 0.43 950410.0 349000.0 0.49 0.6471 0.998 1537010 Maybridge1_005943 CCOC(=O)n1c(=O)c2cc(C)ccc2[nH]c1=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G04 compound treatment 907269.0 310000.0 0.44 982867.0 381000.0 0.53 0.6883 0.9957 2072479 Maybridge1_005944 Oc1c(Cl)cc(Cl)cc1/C=N/NC(=S)NCC2CCCO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G05 compound treatment 910366.0 313000.0 0.45 903526.0 302000.0 0.42 0.6132 0.9996 2072480 Maybridge1_005945 COc1ccc(cc1)C(=O)CC(Sc2ccccc2)c3ccc(cc3)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G06 compound treatment 890322.0 293000.0 0.42 1001865.0 400000.0 0.56 0.69 0.9897 2072481 Maybridge1_005946 Clc1ccc(/C=N/c2cccnc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G07 compound treatment 915884.0 319000.0 0.45 967427.0 366000.0 0.51 0.6817 0.9983 1395171 Maybridge1_005947 CC1C(OCCN1C(=O)CCC(=O)N2CCOC(C2C)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G08 compound treatment 874208.0 277000.0 0.39 907645.0 306000.0 0.43 0.5809 0.9992 2072482 Maybridge1_005948 [O-][N+](=O)/C=C/c1c([nH]c2ccccc12)c3ccc4ccccc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G09 compound treatment 933287.0 336000.0 0.48 963834.0 362000.0 0.51 0.6957 0.9996 2072483 Maybridge1_005949 [O-][N+](=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G10 compound treatment 920125.0 323000.0 0.46 947771.0 346000.0 0.48 0.6666 0.9997 2072484 Maybridge1_005950 CCCOc1ccccc1/C=N/NC(=S)Nc2ccc(C)c(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G11 compound treatment 910787.0 314000.0 0.45 1010600.0 409000.0 0.57 0.7192 0.9926 1019401 Maybridge1_005951 CCOC(=O)C(N)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G12 compound treatment 898088.0 301000.0 0.43 903788.0 302000.0 0.42 0.6011 1.0 1696641 Maybridge1_005952 Fc1cccc(Nc2ccccc2C(=O)OCC(=O)c3ccccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G13 compound treatment 921443.0 325000.0 0.46 1020921.0 420000.0 0.59 0.7401 0.9931 2072485 Maybridge1_005953 Cc1ccc2nsnc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G14 compound treatment 899829.0 303000.0 0.43 964922.0 364000.0 0.51 0.6631 0.9967 2072486 Maybridge1_005954 Cc1onc(c1C(=O)OCC(=O)c2ccc(Cl)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G15 compound treatment 937128.0 340000.0 0.48 1008436.0 407000.0 0.57 0.7435 0.9968 2072487 Maybridge1_005955 FC(F)(F)c1cc(Cl)c2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G16 compound treatment 918516.0 322000.0 0.46 986543.0 385000.0 0.54 0.7032 0.9968 1032061 Maybridge1_005956 CSc1nc(O)cc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G17 compound treatment 957621.0 361000.0 0.51 1015339.0 414000.0 0.58 0.771 0.9983 2072488 Maybridge1_005957 CCOC(=O)[C@H](CCCNC(=N)N)NC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G18 compound treatment 951215.0 354000.0 0.5 1004983.0 404000.0 0.56 0.7543 0.9985 1077975 Maybridge1_005958 COc1cc(CCC(=O)O)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G19 compound treatment 944248.0 347000.0 0.49 1045879.0 445000.0 0.62 0.7876 0.9937 2072489 Maybridge1_005959 OC(=O)CCNC(=S)Nc1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G20 compound treatment 911337.0 314000.0 0.45 1005108.0 404000.0 0.56 0.7143 0.9935 1065810 Maybridge1_005960 CNC(=S)NC1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G21 compound treatment 917659.0 321000.0 0.46 1007510.0 406000.0 0.57 0.723 0.9942 2072490 Maybridge1_005961 Sc1nccn1c2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G22 compound treatment 932748.0 336000.0 0.48 968523.0 367000.0 0.51 0.6998 0.9994 1310850 Maybridge1_005962 COc1ccc(CCNC(=S)Nc2ccc(Br)c(C)c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G23 mock treatment 934172.0 337000.0 0.48 974831.0 373000.0 0.52 0.7074 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 G24 mock treatment 151335.0 -446000.0 -0.63 153525.0 -448000.0 -0.62 -0.8897 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H01 compound treatment 873846.0 277000.0 0.39 843863.0 242000.0 0.34 0.5176 0.9971 2072491 Maybridge1_005963 [O-][N+](=O)c1ccc(OCCCCOc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H02 compound treatment 852836.0 256000.0 0.36 841789.0 240000.0 0.34 0.4944 0.9992 2072492 Maybridge1_005964 Clc1ccc(SC(=S)Nc2cc(Cl)ccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H03 compound treatment 938996.0 342000.0 0.49 960201.0 359000.0 0.5 0.6978 0.9999 1085517 Maybridge1_005965 Nc1nc(N)nc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H04 compound treatment 894668.0 298000.0 0.42 914799.0 313000.0 0.44 0.6085 0.9999 2072493 Maybridge1_005966 Cc1onc(c1C#N)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H05 compound treatment 916868.0 320000.0 0.45 956009.0 355000.0 0.49 0.6715 0.9991 1698586 Maybridge1_005967 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2c(C)cccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H06 compound treatment 914938.0 318000.0 0.45 970801.0 369000.0 0.52 0.6841 0.9979 1023952 Maybridge1_005968 O=C1CC(=NO1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H07 compound treatment 925629.0 329000.0 0.47 895159.0 294000.0 0.41 0.6203 0.9978 1205192 Maybridge1_005969 Clc1ccc(Oc2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H08 compound treatment 961176.0 364000.0 0.52 944572.0 343000.0 0.48 0.7047 0.9992 2072494 Maybridge1_005970 FC(F)(F)c1cc(N/N=C\2/C(=O)ON=C2c3ccccc3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H09 compound treatment 1008426.0 411000.0 0.59 1010705.0 409000.0 0.57 0.8175 0.9999 2072495 Maybridge1_005971 [O-][N+](=O)c1ccc(cc1)c2cc3cc(Cl)ccc3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H10 compound treatment 958439.0 362000.0 0.51 850335.0 249000.0 0.35 0.609 0.9817 2072496 Maybridge1_005972 CCOC(=O)c1c(Cl)c(nc(O)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H11 compound treatment 944211.0 347000.0 0.49 975598.0 374000.0 0.52 0.7183 0.9996 1540102 Maybridge1_005973 NCCSC(=S)NC1CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H12 compound treatment 901645.0 305000.0 0.43 940835.0 339000.0 0.47 0.6412 0.999 2072497 Maybridge1_005974 CN(C)C(=O)Oc1noc2cc(Cl)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H13 compound treatment 943631.0 347000.0 0.49 1008174.0 407000.0 0.57 0.7498 0.9976 2072498 Maybridge1_005975 OC(=O)C1=Cc2cc(Cl)ccc2OC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H14 compound treatment 945395.0 348000.0 0.5 1004503.0 403000.0 0.56 0.748 0.998 2072499 Maybridge1_005976 Cc1onc(c1NC(=O)O/N=C/c2ccccn2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H15 compound treatment 988178.0 391000.0 0.56 970596.0 369000.0 0.51 0.7576 0.9993 1330733 Maybridge1_005977 Cc1cc(C)c(C#N)c(OC(=O)c2cccs2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H16 compound treatment 985837.0 389000.0 0.55 994354.0 393000.0 0.55 0.7786 1.0 2072500 Maybridge1_005978 CCOC(=O)c1nnn(c1O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H17 compound treatment 992341.0 395000.0 0.56 953470.0 352000.0 0.49 0.7448 0.9977 1719106 Maybridge1_005979 Cc1cc(C)c2c(c(sc2n1)C(=O)c3ccc(Cl)cc3)n4cccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H18 compound treatment 953592.0 357000.0 0.51 962585.0 361000.0 0.5 0.7149 1.0 2072501 Maybridge1_005980 [O-][N+](=O)c1ccc(C#N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H19 compound treatment 1688313.0 1090000.0 1.55 1864231.0 1260000.0 1.76 2.3429 0.998 2072502 Maybridge1_005981 CC(=O)c1sc2nc(cc(c2c1N)C(F)(F)F)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H20 compound treatment 951844.0 355000.0 0.5 973081.0 372000.0 0.52 0.7235 0.9999 1604442 Maybridge1_005982 N#Cc1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H21 compound treatment 977247.0 380000.0 0.54 1004460.0 403000.0 0.56 0.78 0.9998 2072503 Maybridge1_005983 Nc1ccccc1SC(C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H22 compound treatment 993650.0 397000.0 0.56 987319.0 386000.0 0.54 0.7795 0.9997 2072504 Maybridge1_005984 N/C(=N\O)/c1ccc(OCc2ccc(Cl)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H23 mock treatment 976140.0 379000.0 0.54 986038.0 385000.0 0.54 0.7607 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 H24 mock treatment 157863.0 -439000.0 -0.62 157989.0 -443000.0 -0.62 -0.8788 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I01 compound treatment 844394.0 247000.0 0.35 822654.0 221000.0 0.31 0.4671 0.9979 2072505 Maybridge1_005985 Cc1ccc(/N=C/c2cccs2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I02 compound treatment 860167.0 263000.0 0.37 911647.0 310000.0 0.43 0.5707 0.9974 1187362 Maybridge1_005986 Nc1cc(O)n(Cc2ccco2)c(=S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I03 compound treatment 917138.0 320000.0 0.46 936910.0 336000.0 0.47 0.6529 0.9999 2072506 Maybridge1_005987 CCOC(=O)NC(=S)NCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I04 compound treatment 905586.0 309000.0 0.44 951515.0 350000.0 0.49 0.6557 0.9986 2072507 Maybridge1_005988 COc1ccc(/C=N/NC(=S)NCC2CCCO2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I05 compound treatment 903416.0 306000.0 0.44 980053.0 379000.0 0.53 0.6816 0.9954 1524757 Maybridge1_005989 Clc1ccc2c(=O)[nH]c(=O)[nH]c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I06 compound treatment 915059.0 318000.0 0.45 943547.0 342000.0 0.48 0.6574 0.9996 2072508 Maybridge1_005990 CSc1cccc(NC(=O)/C=C/C(=O)O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I07 compound treatment 930715.0 334000.0 0.47 959638.0 358000.0 0.5 0.689 0.9997 1089852 Maybridge1_005991 ON1C(=O)C2C3OC(C=C3)C2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I08 compound treatment 906946.0 310000.0 0.44 903864.0 302000.0 0.42 0.6101 0.9998 2072509 Maybridge1_005992 C/C(=N\Nc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])/c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I09 compound treatment 932179.0 335000.0 0.48 958031.0 357000.0 0.5 0.6889 0.9998 1446187 Maybridge1_005993 COC(=O)c1ccc(NC(=O)C)c(NC(=O)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I10 compound treatment 952520.0 356000.0 0.51 975489.0 374000.0 0.52 0.7265 0.9999 2072510 Maybridge1_005994 CCCOc1ccccc1/C=N/NC(=S)Nc2cc(Cl)ccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I11 compound treatment 928700.0 332000.0 0.47 964315.0 363000.0 0.51 0.6915 0.9994 2072511 Maybridge1_005995 COC(=O)c1ccc2[nH]nnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I12 compound treatment 916379.0 319000.0 0.45 920460.0 319000.0 0.45 0.6359 0.9999 1147787 Maybridge1_005996 O=C(COC(=O)c1ccccc1NCc2ccco2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I13 compound treatment 908037.0 311000.0 0.44 985075.0 384000.0 0.54 0.6912 0.9955 1005880 Maybridge1_005997 [O-][N+](=O)C1C(=O)NC(=O)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I14 compound treatment 926393.0 329000.0 0.47 1011383.0 410000.0 0.57 0.7356 0.9951 1242165 Maybridge1_005998 O=C(COC(=O)c1ccccc1C(=O)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I15 compound treatment 989484.0 393000.0 0.56 941688.0 340000.0 0.47 0.7304 0.9967 1040518 Maybridge1_005999 Cc1cc2nc(C)c(C)nc2cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I16 compound treatment 935205.0 338000.0 0.48 1010261.0 409000.0 0.57 0.7434 0.9964 1590570 Maybridge1_006000 COc1cccc(C2NC(=O)c3ccccc3N2)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I17 compound treatment 968503.0 372000.0 0.53 999625.0 398000.0 0.56 0.7664 0.9997 1351125 Maybridge1_006001 CC(=O)Nc1ccc(cc1NC(=O)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I18 compound treatment 932937.0 336000.0 0.48 998075.0 397000.0 0.55 0.7291 0.9973 2072512 Maybridge1_006002 Cc1cc(C)c(NC(=N)NC(=N)NN)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I19 compound treatment 967932.0 371000.0 0.53 1023357.0 422000.0 0.59 0.7892 0.9985 1428290 Maybridge1_006003 OC(=O)CCNC(=S)Nc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I20 compound treatment 895689.0 299000.0 0.42 997808.0 396000.0 0.55 0.6914 0.9915 2072513 Maybridge1_006004 C/N=C(/NC1CCCCC1)\SCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I21 compound treatment 968066.0 371000.0 0.53 1008291.0 407000.0 0.57 0.7745 0.9993 2072514 Maybridge1_006005 COCCC[n+]1c(C)csc1Nc2c(C)cc(C)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I22 compound treatment 928477.0 332000.0 0.47 995554.0 394000.0 0.55 0.7221 0.9971 2072515 Maybridge1_006006 CC[n+]1c(C)csc1Nc2c(C)cccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I23 mock treatment 980712.0 384000.0 0.55 1004724.0 403000.0 0.56 0.7837 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 I24 mock treatment 163720.0 -433000.0 -0.62 143928.0 -457000.0 -0.64 -0.8868 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J01 compound treatment 895573.0 299000.0 0.42 866397.0 265000.0 0.37 0.5617 0.9976 2072516 Maybridge1_006007 CCOC(=O)c1ccc(cc1)c2ccc(/C=N/NC(=S)Nc3ccc(OC)cc3)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J02 compound treatment 895382.0 298000.0 0.42 884474.0 283000.0 0.39 0.5793 0.9993 2072517 Maybridge1_006008 FC(F)(F)c1ccc(Cl)c(NC(=S)Sc2ccc(Cl)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J03 compound treatment 944184.0 347000.0 0.49 971690.0 370000.0 0.52 0.7144 0.9997 2072518 Maybridge1_006009 OC(=O)c1cc(ccc1NCc2ccco2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J04 compound treatment 911888.0 315000.0 0.45 934805.0 333000.0 0.47 0.6455 0.9998 2072519 Maybridge1_006010 Cc1onc(c1C(=O)N)c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J05 compound treatment 937011.0 340000.0 0.48 934968.0 334000.0 0.47 0.671 0.9998 1724484 Maybridge1_006011 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J06 compound treatment 902091.0 305000.0 0.43 952426.0 351000.0 0.49 0.6531 0.9982 2072520 Maybridge1_006012 O/N=C\1/C(=O)ON=C1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J07 compound treatment 947556.0 351000.0 0.5 987440.0 386000.0 0.54 0.7333 0.9993 2072521 Maybridge1_006013 COc1ccc(OS(=O)(=O)c2ccc(NC(=O)C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J08 compound treatment 967765.0 371000.0 0.53 965704.0 364000.0 0.51 0.7322 0.9998 2072522 Maybridge1_006014 CN(C)/C=N/c1nonc1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J09 compound treatment 993721.0 397000.0 0.56 1014155.0 413000.0 0.58 0.8061 0.9999 2072523 Maybridge1_006015 FC(F)(F)c1cc(NC(=O)CN2CCOCC2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J10 compound treatment 967050.0 370000.0 0.53 960996.0 360000.0 0.5 0.7268 0.9997 2072524 Maybridge1_006016 Nc1c(Cl)cncc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J11 compound treatment 970109.0 373000.0 0.53 1002083.0 401000.0 0.56 0.7704 0.9997 2072525 Maybridge1_006017 Cc1cccc(C)c1N=C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J12 compound treatment 889640.0 293000.0 0.42 948683.0 347000.0 0.48 0.6369 0.9972 2072526 Maybridge1_006018 CN(C)C(=O)Oc1noc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J13 compound treatment 942074.0 345000.0 0.49 1010885.0 410000.0 0.57 0.7509 0.9972 1462709 Maybridge1_006019 Cc1cc(=O)[nH]c(n1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J14 compound treatment 897045.0 300000.0 0.43 938868.0 337000.0 0.47 0.6346 0.9988 2072527 Maybridge1_006020 Cc1onc(c1NC(=O)O/N=C/c2cccnc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J15 compound treatment 962692.0 366000.0 0.52 1033244.0 432000.0 0.6 0.7937 0.9973 2072528 Maybridge1_006021 Clc1cc(Cl)c(NC(=O)C(Cl)(Cl)Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J16 compound treatment 959572.0 363000.0 0.52 959047.0 358000.0 0.5 0.7174 0.9999 1029309 Maybridge1_006022 CC(=O)Nc1ccc(cc1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J17 compound treatment 981398.0 384000.0 0.55 1009121.0 408000.0 0.57 0.7887 0.9998 2072529 Maybridge1_006023 COc1nc(C)cc(C)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J18 compound treatment 949030.0 352000.0 0.5 963084.0 362000.0 0.5 0.7108 1.0 2072530 Maybridge1_006024 CC(C)(C)c1ccc(NC(=O)c2ccco2)c(NC(=O)C(Cl)Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J19 compound treatment 928371.0 331000.0 0.47 1012656.0 411000.0 0.57 0.7389 0.9952 2072531 Maybridge1_006025 FC(F)(F)c1cc(NC(=O)C(Sc2ccc(Cl)cc2)c3ccccc3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J20 compound treatment 935776.0 339000.0 0.48 1007439.0 406000.0 0.57 0.7412 0.9968 1095814 Maybridge1_006026 Oc1nc(nc(n1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J21 compound treatment 1098381.0 501000.0 0.71 1059200.0 458000.0 0.64 0.9558 0.9985 1782371 Maybridge1_006027 CCOC(=O)C1=C(C)NC(=O)NC1c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J22 compound treatment 955565.0 359000.0 0.51 981259.0 380000.0 0.53 0.7353 0.9998 1679639 Maybridge1_006028 Clc1ccc(cc1)C(=O)CSC(=S)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J23 mock treatment 1023043.0 426000.0 0.61 975854.0 374000.0 0.52 0.7978 0.9973 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 J24 mock treatment 165208.0 -432000.0 -0.61 167303.0 -434000.0 -0.61 -0.8622 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K01 compound treatment 842596.0 246000.0 0.35 811059.0 210000.0 0.29 0.4538 0.9961 2072532 Maybridge1_006029 Oc1ccc(/N=C/c2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K02 compound treatment 857426.0 260000.0 0.37 886569.0 285000.0 0.4 0.5432 0.9994 2072533 Maybridge1_006030 CC(C)(C)NC(=S)N/N=C/c1cccnc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K03 compound treatment 908533.0 312000.0 0.44 947539.0 346000.0 0.48 0.6547 0.9991 2072534 Maybridge1_006031 C=CCN(CC=C)C(=S)NC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K04 compound treatment 869704.0 273000.0 0.39 855465.0 254000.0 0.35 0.5249 0.999 2072535 Maybridge1_006032 COc1cc(/C=N/NC(=S)NCC2CCCO2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K05 compound treatment 901334.0 304000.0 0.43 908764.0 307000.0 0.43 0.6092 1.0 2072536 Maybridge1_006033 COc1ccc(OC)c(NC2=NCCS2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K06 compound treatment 873599.0 277000.0 0.39 938850.0 337000.0 0.47 0.611 0.996 2072537 Maybridge1_006034 Clc1cccc(NC(=S)N/N=C/c2ccccc2Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K07 compound treatment 912896.0 316000.0 0.45 945293.0 344000.0 0.48 0.6569 0.9995 1697868 Maybridge1_006035 O=C(ON1C(=O)C2C3OC(C=C3)C2C1=O)Oc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K08 compound treatment 886391.0 289000.0 0.41 932413.0 331000.0 0.46 0.6175 0.9984 2072538 Maybridge1_006036 Cc1ccc(C2N=NNC2=S)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K09 compound treatment 937119.0 340000.0 0.48 952792.0 351000.0 0.49 0.6887 1.0 2072539 Maybridge1_006037 Fc1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K10 compound treatment 925063.0 328000.0 0.47 961856.0 360000.0 0.5 0.6855 0.9993 1603 Maybridge1_006038 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K11 compound treatment 901206.0 304000.0 0.43 963161.0 362000.0 0.5 0.6628 0.9971 2072540 Maybridge1_006039 FC(F)(F)c1ccc2nsnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K12 compound treatment 871360.0 274000.0 0.39 898130.0 297000.0 0.41 0.5686 0.9996 1228269 Maybridge1_006040 Oc1ccccc1C(=O)Nc2ccc(NC(=S)NCCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K13 compound treatment 910161.0 313000.0 0.45 998024.0 397000.0 0.55 0.7062 0.9942 2072541 Maybridge1_006041 CC(C)(C)C(=O)Nc1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K14 compound treatment 906045.0 309000.0 0.44 921250.0 320000.0 0.45 0.6263 1.0 1437700 Maybridge1_006042 Nc1cccc(NC(=O)c2ccccc2O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K15 compound treatment 922754.0 326000.0 0.46 1008858.0 407000.0 0.57 0.7295 0.9949 2072542 Maybridge1_006043 COC(=O)c1ccc2nc(C)c(C)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K16 compound treatment 867322.0 270000.0 0.38 944027.0 343000.0 0.48 0.6098 0.9942 1579367 Maybridge1_006044 Oc1cccc(C(=O)OCC(=O)c2ccc(Cl)cc2)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K17 compound treatment 941385.0 344000.0 0.49 960193.0 359000.0 0.5 0.7002 0.9999 2072543 Maybridge1_006045 CCC(=O)Oc1ccc(NC(=S)NCCCO)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K18 compound treatment 934832.0 338000.0 0.48 955640.0 354000.0 0.49 0.6892 0.9999 2072544 Maybridge1_006046 NNC(=N)NC(=N)Nc1cccc(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K19 compound treatment 954847.0 358000.0 0.51 978307.0 377000.0 0.53 0.7316 0.9999 2072545 Maybridge1_006047 Clc1ccc(NC(=S)NCc2ccco2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K20 compound treatment 897279.0 300000.0 0.43 993372.0 392000.0 0.55 0.6886 0.9925 2072546 Maybridge1_006048 Cc1csc(NC2CCCCC2)[n+]1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K21 compound treatment 941624.0 345000.0 0.49 984340.0 383000.0 0.53 0.7243 0.9991 2072547 Maybridge1_006049 FC(F)(F)c1cc(/N=C/2\NCCN/C(=N/c3cc(cc(c3)C(F)(F)F)C(F)(F)F)/SS2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K22 compound treatment 882743.0 286000.0 0.41 958476.0 357000.0 0.5 0.6396 0.9949 2072548 Maybridge1_006050 Cc1csc(Nc2ccc(C)cc2C)[n+]1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K23 mock treatment 961349.0 364000.0 0.52 996540.0 395000.0 0.55 0.7562 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 K24 mock treatment 148800.0 -448000.0 -0.64 140125.0 -461000.0 -0.64 -0.9055 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L01 compound treatment 844711.0 248000.0 0.35 810405.0 209000.0 0.29 0.4553 0.9956 1088868 Maybridge1_006051 Nc1nc(N)nc(n1)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L02 compound treatment 862665.0 266000.0 0.38 877744.0 276000.0 0.39 0.5398 1.0 2072549 Maybridge1_006052 Cc1onc(c1CO)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L03 compound treatment 920090.0 323000.0 0.46 945469.0 344000.0 0.48 0.6643 0.9998 2072550 Maybridge1_006053 OC(=O)c1cc(ccc1NCCc2ccccc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L04 compound treatment 897554.0 301000.0 0.43 924583.0 323000.0 0.45 0.621 0.9996 1015353 Maybridge1_006054 CCOC(=O)c1cc(C)nc(O)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L05 compound treatment 900912.0 304000.0 0.43 918490.0 317000.0 0.44 0.6184 0.9999 1192699 Maybridge1_006055 CC(Oc1ccc(I)cc1)C(=O)Nc2ccc(Br)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L06 compound treatment 871250.0 274000.0 0.39 938512.0 337000.0 0.47 0.6083 0.9957 2072551 Maybridge1_006056 CNC(=O)O/N=C(\N)/c1c(C)onc1c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L07 compound treatment 893180.0 296000.0 0.42 928148.0 327000.0 0.46 0.6202 0.9992 2072552 Maybridge1_006057 Clc1ccc(cc1)c2[nH]c3ccccc3c2/C=N/NC(=S)NCCc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L08 compound treatment 881784.0 285000.0 0.41 957583.0 356000.0 0.5 0.6377 0.9949 1199365 Maybridge1_006058 CCOC(=O)c1cc(nc(O)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L09 compound treatment 902276.0 305000.0 0.43 963229.0 362000.0 0.5 0.6639 0.9972 2072553 Maybridge1_006059 FC(F)(F)c1cc(NC(=O)CN2CCCCC2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L10 compound treatment 886423.0 289000.0 0.41 934001.0 333000.0 0.46 0.6191 0.9982 2072554 Maybridge1_006060 Cc1onc(c1C(=O)NNc2c(Cl)cncc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L11 compound treatment 907099.0 310000.0 0.44 948917.0 348000.0 0.48 0.6546 0.9989 2072555 Maybridge1_006061 OC(c1cccc(c1)[N+](=O)[O-])C(Cl)(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L12 compound treatment 910666.0 314000.0 0.45 928442.0 327000.0 0.46 0.638 0.9999 2072556 Maybridge1_006062 Cc1onc(c1NC(=O)O/N=C/c2ccc(Cl)c(Cl)c2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L13 compound treatment 900492.0 304000.0 0.43 945413.0 344000.0 0.48 0.6445 0.9986 2072557 Maybridge1_006063 Cc1nc(nc(S)c1Cl)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L14 compound treatment 860520.0 264000.0 0.37 935185.0 334000.0 0.47 0.5943 0.9942 1616538 Maybridge1_006064 CNC(=O)Oc1noc2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L15 compound treatment 963383.0 366000.0 0.52 988796.0 387000.0 0.54 0.7506 0.9998 1104196 Maybridge1_006065 CCOC(=O)c1sc2nc(C)cc(C)c2c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L16 compound treatment 953743.0 357000.0 0.51 938768.0 337000.0 0.47 0.6915 0.9993 1294656 Maybridge1_006066 COC(=O)COc1c(C)nccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L17 compound treatment 962450.0 366000.0 0.52 943687.0 342000.0 0.48 0.7051 0.9991 2072558 Maybridge1_006067 Cc1cc(C)c(C#N)c(SC(=O)c2c(F)cccc2F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L18 compound treatment 921812.0 325000.0 0.46 945080.0 344000.0 0.48 0.6657 0.9998 2072559 Maybridge1_006068 CCOC(=O)c1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L19 compound treatment 940276.0 343000.0 0.49 967058.0 366000.0 0.51 0.7059 0.9998 2072560 Maybridge1_006069 FC(F)(F)c1cc(NC(=O)C(Sc2ccccn2)c3ccccc3)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L20 compound treatment 942323.0 345000.0 0.49 1005936.0 405000.0 0.56 0.7463 0.9976 1203411 Maybridge1_006070 Clc1ccc(COc2ccc(C#N)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L21 compound treatment 983718.0 387000.0 0.55 1032636.0 431000.0 0.6 0.8143 0.999 1192282 Maybridge1_006071 CCOC(=O)C1=C(C)NC(=O)NC1c2cccc(OC)c2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L22 compound treatment 973846.0 377000.0 0.54 980312.0 379000.0 0.53 0.7527 1.0 2072561 Maybridge1_006072 CS/C(=N\C#N)/NCc1cccnc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L23 mock treatment 964519.0 368000.0 0.52 1005580.0 404000.0 0.56 0.7683 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 L24 mock treatment 172825.0 -424000.0 -0.6 149774.0 -452000.0 -0.63 -0.8718 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M01 compound treatment 816691.0 220000.0 0.31 830479.0 229000.0 0.32 0.4469 0.9999 2072562 Maybridge1_006073 Sc1nnc(Nc2ccccc2Cl)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M02 compound treatment 859792.0 263000.0 0.37 869571.0 268000.0 0.37 0.5288 1.0 1539962 Maybridge1_006074 CC(NC(=S)Nc1ccc(Oc2ccc(Cl)cc2)cc1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M03 compound treatment 930562.0 334000.0 0.47 948507.0 347000.0 0.48 0.6778 0.9999 2072563 Maybridge1_006075 O=C(NC(=S)NCc1ccncc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M04 compound treatment 832785.0 236000.0 0.34 898498.0 297000.0 0.41 0.5302 0.9945 2072564 Maybridge1_006076 COc1ccc(cc1)/C(=C/c2cc(OC)c(OC)c(OC)c2)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M05 compound treatment 849475.0 253000.0 0.36 947807.0 346000.0 0.48 0.5956 0.9893 1083150 Maybridge1_006077 COc1cccc(NC(=S)NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M06 compound treatment 882074.0 285000.0 0.41 942176.0 341000.0 0.48 0.6228 0.9969 1121329 Maybridge1_006078 OC(=O)CCC(=O)Nc1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M07 compound treatment 918061.0 321000.0 0.46 922904.0 322000.0 0.45 0.64 1.0 1107198 Maybridge1_006079 CCOC(=O)c1cncc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M08 compound treatment 846512.0 250000.0 0.35 893724.0 292000.0 0.41 0.5393 0.9976 2072565 Maybridge1_006080 COc1cccc(/N=C/c2cc(OC)c(OC)c(OC)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M09 compound treatment 914314.0 317000.0 0.45 901678.0 300000.0 0.42 0.6153 0.9993 2072566 Maybridge1_006081 COC(=O)c1ccc2nccnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M10 compound treatment 840791.0 244000.0 0.35 897647.0 296000.0 0.41 0.5374 0.9962 2072567 Maybridge1_006082 Cc1cccc(C)c1n2nnnc2SCc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M11 compound treatment 924654.0 328000.0 0.47 978644.0 377000.0 0.53 0.7016 0.9982 2072568 Maybridge1_006083 Cc1cc2nsnc2cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M12 compound treatment 901653.0 305000.0 0.43 919573.0 318000.0 0.44 0.6202 0.9999 1334594 Maybridge1_006084 Oc1ccccc1C(=O)Nc2ccc(NC(=S)Nc3cccc(Cl)c3Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M13 compound treatment 902074.0 305000.0 0.43 1007342.0 406000.0 0.57 0.7072 0.9914 1653923 Maybridge1_006085 CC1(C)C2CCC1(C)C(N)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M14 compound treatment 896338.0 299000.0 0.43 941358.0 340000.0 0.47 0.6364 0.9986 2072569 Maybridge1_006086 CCCc1c(C)nc2scc(c3ccccc3)n2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M15 compound treatment 919521.0 323000.0 0.46 952379.0 351000.0 0.49 0.6705 0.9995 1015121 Maybridge1_006087 CCOC(=O)CNC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M16 compound treatment 899921.0 303000.0 0.43 897638.0 296000.0 0.41 0.5969 0.9998 2072570 Maybridge1_006088 Cc1cc(C)c(NC(=S)NCCCN2CCOCC2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M17 compound treatment 947102.0 350000.0 0.5 986542.0 385000.0 0.54 0.732 0.9993 2072571 Maybridge1_006089 Nc1ccccc1NC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M18 compound treatment 932818.0 336000.0 0.48 922455.0 321000.0 0.45 0.6544 0.9995 1450707 Maybridge1_006090 OCCNC(=S)NC1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M19 compound treatment 958029.0 361000.0 0.51 986320.0 385000.0 0.54 0.7427 0.9998 2072572 Maybridge1_006091 COc1ccccc1/N=C/2\SCC(=O)N2Cc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M20 compound treatment 916128.0 319000.0 0.45 926615.0 325000.0 0.45 0.6417 1.0 2072573 Maybridge1_006092 Oc1cc(nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M21 compound treatment 949831.0 353000.0 0.5 1013623.0 412000.0 0.57 0.7614 0.9977 1514590 Maybridge1_006093 Fc1ccc(NC(=S)Nc2ccc3cn[nH]c3c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M22 compound treatment 914454.0 318000.0 0.45 924912.0 324000.0 0.45 0.6384 1.0 2072574 Maybridge1_006094 Cc1csc(Nc2cccc3ccccc23)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M23 mock treatment 934344.0 337000.0 0.48 972267.0 371000.0 0.52 0.7051 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 M24 mock treatment 725610.0 129000.0 0.18 714411.0 113000.0 0.16 0.2409 0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N01 compound treatment 850492.0 254000.0 0.36 851625.0 250000.0 0.35 0.5018 0.9999 2072575 Maybridge1_006095 CS/C(=N\C)/Nc1cc(C)c(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N02 compound treatment 839818.0 243000.0 0.35 896113.0 295000.0 0.41 0.5349 0.9963 2072576 Maybridge1_006096 COc1ccc(OC)c(Sc2nc(C)c([N+](=O)[O-])c(C)c2C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N03 compound treatment 918507.0 322000.0 0.46 966380.0 365000.0 0.51 0.6833 0.9986 2067914 Maybridge1_006097 C=CCSc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N04 compound treatment 893005.0 296000.0 0.42 928995.0 328000.0 0.46 0.6208 0.9992 1012507 Maybridge1_006098 CCOC(=O)c1c(C#N)c(O)nc(C)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N05 compound treatment 923134.0 326000.0 0.46 946322.0 345000.0 0.48 0.6682 0.9998 2072577 Maybridge1_006099 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=N/O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N06 compound treatment 851798.0 255000.0 0.36 914220.0 313000.0 0.44 0.5648 0.9958 2072578 Maybridge1_006100 Cc1nc(O)c(C#N)c(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N07 compound treatment 974349.0 377000.0 0.54 977514.0 376000.0 0.52 0.7505 0.9999 2072579 Maybridge1_006101 Nc1ncnc(Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N08 compound treatment 870802.0 274000.0 0.39 947724.0 346000.0 0.48 0.617 0.9943 2072580 Maybridge1_006102 Cc1nc(nc(O)c1Cl)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N09 compound treatment 935023.0 338000.0 0.48 958219.0 357000.0 0.5 0.6919 0.9999 2072581 Maybridge1_006103 COc1cc(/C=N/OC(=O)c2ccc(Cl)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N10 compound treatment 888682.0 292000.0 0.41 941202.0 340000.0 0.47 0.6285 0.9978 2072582 Maybridge1_006104 Brc1coc2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N11 compound treatment 921196.0 324000.0 0.46 982777.0 381000.0 0.53 0.7022 0.9975 2072583 Maybridge1_006105 OC(=O)COc1ccc(OC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N12 compound treatment 905518.0 309000.0 0.44 963497.0 362000.0 0.51 0.6674 0.9975 2072584 Maybridge1_006106 Cc1onc(c1NC(=O)O/N=C/c2ccc(Cl)cc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N13 compound treatment 940387.0 343000.0 0.49 977900.0 377000.0 0.53 0.7167 0.9993 1007516 Maybridge1_006107 Cc1cc(cc(C)c1[N+](=O)[O-])C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N14 compound treatment 923248.0 326000.0 0.46 890125.0 289000.0 0.4 0.6129 0.9975 2072585 Maybridge1_006108 Clc1ccc(NC(=O)NNc2c(Cl)cncc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N15 compound treatment 924548.0 328000.0 0.47 1014507.0 413000.0 0.58 0.7369 0.9944 2072586 Maybridge1_006109 CSc1nc(C)cc(C)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N16 compound treatment 914236.0 317000.0 0.45 944730.0 343000.0 0.48 0.6577 0.9996 2072587 Maybridge1_006110 CCOC(=O)NC(=S)Nc1ccc(cc1NC(=S)NC(=O)OCC)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N17 compound treatment 940835.0 344000.0 0.49 958838.0 357000.0 0.5 0.6984 1.0 2072588 Maybridge1_006111 FC(F)(F)c1cc(N=NN2CCOCC2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N18 compound treatment 937074.0 340000.0 0.48 962681.0 361000.0 0.5 0.6984 0.9998 1552789 Maybridge1_006112 Cc1nccc(O)c1OCc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N19 compound treatment 975382.0 378000.0 0.54 1026347.0 425000.0 0.59 0.7997 0.9988 2072589 Maybridge1_006113 CCc1cccc(CC)c1NC(=O)C(Sc2ccccn2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N20 compound treatment 936420.0 339000.0 0.48 963122.0 362000.0 0.5 0.6981 0.9998 2072590 Maybridge1_006114 N/C(=N\O)/c1ccc(OCc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N21 compound treatment 980322.0 383000.0 0.55 1020146.0 419000.0 0.58 0.7985 0.9994 2072591 Maybridge1_006115 Sc1nnc([nH]1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N22 compound treatment 945219.0 348000.0 0.5 1011256.0 410000.0 0.57 0.7545 0.9974 2072592 Maybridge1_006116 CS/C(=N\C#N)/NCc1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N23 mock treatment 951347.0 354000.0 0.5 982787.0 381000.0 0.53 0.7325 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 N24 mock treatment 719935.0 123000.0 0.17 616362.0 15000.0 0.02 0.1385 0.786 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O01 compound treatment 834030.0 237000.0 0.34 822612.0 221000.0 0.31 0.4566 0.999 2072593 Maybridge1_006117 Cc1ccc(Nc2nnc(S)s2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O02 compound treatment 779808.0 183000.0 0.26 814872.0 213000.0 0.3 0.3944 0.9977 2072594 Maybridge1_006118 COCCCNC(=S)Nc1ccc(Oc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O03 compound treatment 869008.0 272000.0 0.39 893427.0 292000.0 0.41 0.5616 0.9997 2072595 Maybridge1_006119 NC(=S)NCc1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O04 compound treatment 850725.0 254000.0 0.36 881102.0 280000.0 0.39 0.5311 0.9992 1091572 Maybridge1_006120 Cc1cc(=O)n2c(csc2n1)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O05 compound treatment 898013.0 301000.0 0.43 890485.0 289000.0 0.4 0.5879 0.9996 1065250 Maybridge1_006121 COc1cccc(NC(=S)N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O06 compound treatment 859540.0 263000.0 0.37 882801.0 281000.0 0.39 0.5416 0.9997 2072596 Maybridge1_006122 CSc1nnnn1c2c(C)cccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O07 compound treatment 927461.0 331000.0 0.47 924062.0 323000.0 0.45 0.6506 0.9998 2072597 Maybridge1_006123 NNC(=O)c1cncc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O08 compound treatment 867883.0 271000.0 0.39 901459.0 300000.0 0.42 0.5684 0.9991 2072598 Maybridge1_006124 Cc1cc(NC(=S)N2CCCCC2)ccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O09 compound treatment 937629.0 341000.0 0.48 942387.0 341000.0 0.48 0.6789 1.0 1312083 Maybridge1_006125 COC(=O)c1ccc(NS(=O)(=O)c2ccc(C)cc2)c(NS(=O)(=O)c3ccc(C)cc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O10 compound treatment 895972.0 299000.0 0.43 862673.0 261000.0 0.36 0.5584 0.997 1774250 Maybridge1_006126 [O-][N+](=O)c1ccc(cc1)c2cn3ccccc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O11 compound treatment 899335.0 302000.0 0.43 912008.0 311000.0 0.43 0.6104 1.0 2072599 Maybridge1_006127 CCOC(=O)[C@@H](N)Cc1c[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O12 compound treatment 852708.0 256000.0 0.36 866116.0 265000.0 0.37 0.5183 1.0 1252858 Maybridge1_006128 OC(=O)c1ccccc1NC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O13 compound treatment 932818.0 336000.0 0.48 952886.0 352000.0 0.49 0.6844 0.9999 2072600 Maybridge1_006129 COC(=O)C[C@H](N)C(=O)N[C@H](Cc1ccccc1)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O14 compound treatment 886707.0 290000.0 0.41 896970.0 296000.0 0.41 0.5829 1.0 1206269 Maybridge1_006130 CCCCn1c(O)cc(N)nc1=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O15 compound treatment 942212.0 345000.0 0.49 931533.0 330000.0 0.46 0.6728 0.9995 2072601 Maybridge1_006131 Cc1nc2ccc(cc2nc1C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O16 compound treatment 899017.0 302000.0 0.43 900182.0 299000.0 0.42 0.5985 0.9999 1664455 Maybridge1_006132 COc1ccccc1C(=O)OCC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O17 compound treatment 955613.0 359000.0 0.51 931011.0 330000.0 0.46 0.6858 0.9987 1522957 Maybridge1_006133 Cc1cc(C)c(Nc2nnns2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O18 compound treatment 886195.0 289000.0 0.41 935957.0 335000.0 0.47 0.6208 0.998 2072602 Maybridge1_006134 COc1ccccc1NC(=N)SCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O19 compound treatment 969339.0 372000.0 0.53 899109.0 298000.0 0.42 0.6681 0.9928 2072603 Maybridge1_006135 Cc1csc(Nc2ccc(Cl)cc2)[n+]1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O20 compound treatment 940442.0 344000.0 0.49 925212.0 324000.0 0.45 0.6648 0.9992 1133744 Maybridge1_006136 COc1ccc(CCNC(=S)Nc2c(C)cccc2C)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O21 compound treatment 954140.0 357000.0 0.51 957877.0 356000.0 0.5 0.7108 0.9999 2072604 Maybridge1_006137 Fc1ccccc1/N=C/2\SCC(=O)N2c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O22 compound treatment 897804.0 301000.0 0.43 888111.0 287000.0 0.4 0.5853 0.9994 2072605 Maybridge1_006138 CC(C)(C)c1ccc(OC(=O)c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O23 mock treatment 945784.0 349000.0 0.5 939957.0 339000.0 0.47 0.6847 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 O24 mock treatment 512000.0 -84900.0 -0.12 508375.0 -93000.0 -0.13 -0.1771 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P01 compound treatment 841921.0 245000.0 0.35 825241.0 224000.0 0.31 0.4671 0.9985 2072606 Maybridge1_006139 COc1ccccc1N/C(=N/C)/SC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P02 compound treatment 857890.0 261000.0 0.37 831931.0 231000.0 0.32 0.4898 0.9975 2072607 Maybridge1_006140 Cc1nc(Sc2ccc(Br)cc2)c(C#N)c(C)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P03 compound treatment 836052.0 239000.0 0.34 850051.0 249000.0 0.35 0.4857 1.0 2072608 Maybridge1_006141 CCOC(=O)CSC(=S)Nc1c(C)cc(C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P04 compound treatment 831946.0 235000.0 0.33 849841.0 248000.0 0.35 0.4814 0.9998 2072609 Maybridge1_006142 Cc1onc(c1C#N)c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P05 compound treatment 877800.0 281000.0 0.4 874881.0 274000.0 0.38 0.5522 0.9997 2072610 Maybridge1_006143 FC(F)(F)c1nnc(Nc2ccc(Cl)cc2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P06 compound treatment 902302.0 305000.0 0.43 872802.0 271000.0 0.38 0.5748 0.9977 2072611 Maybridge1_006144 CCOC(=O)c1cc(C)nc(SC)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P07 compound treatment 913276.0 316000.0 0.45 868399.0 267000.0 0.37 0.5814 0.9956 1729679 Maybridge1_006145 Nc1ncnc(Nc2ccccc2F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P08 compound treatment 882493.0 286000.0 0.41 864952.0 264000.0 0.37 0.5471 0.9988 2072612 Maybridge1_006146 Cc1cc(O)nc(n1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P09 compound treatment 875088.0 278000.0 0.4 866380.0 265000.0 0.37 0.5411 0.9994 2072613 Maybridge1_006147 COc1cc(/C=N/OC(=O)c2ccc(Cl)c(Cl)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P10 compound treatment 892627.0 296000.0 0.42 868687.0 267000.0 0.37 0.561 0.9982 1170374 Maybridge1_006148 O=c1c(C#N)coc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P11 compound treatment 870324.0 273000.0 0.39 849183.0 248000.0 0.35 0.5193 0.9983 2072614 Maybridge1_006149 CC(Oc1ccc(OC(F)(F)F)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P12 compound treatment 900198.0 303000.0 0.43 880393.0 279000.0 0.39 0.5801 0.9987 2072615 Maybridge1_006150 Cc1onc(c1NC(=O)O/N=C/c2cccc(c2)[N+](=O)[O-])c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P13 compound treatment 894048.0 297000.0 0.42 892939.0 292000.0 0.41 0.5863 0.9998 2072616 Maybridge1_006151 COCCCNC(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P14 compound treatment 1386556.0 790000.0 1.12 1323933.0 723000.0 1.01 1.5066 0.9985 2072617 Maybridge1_006152 C/C(=N\OC(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl)/c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P15 compound treatment 915303.0 318000.0 0.45 894677.0 293000.0 0.41 0.6094 0.9987 2072618 Maybridge1_006153 Cc1cc(C)c(C#N)c(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P16 compound treatment 910642.0 314000.0 0.45 905814.0 304000.0 0.42 0.6157 0.9997 2072619 Maybridge1_006154 CC(=NOC(=O)Nc1ccc(cc1)C(F)(F)F)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P17 compound treatment 921829.0 325000.0 0.46 914288.0 313000.0 0.44 0.6353 0.9996 2072620 Maybridge1_006155 Oc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P18 compound treatment 929256.0 332000.0 0.47 905593.0 304000.0 0.42 0.6342 0.9986 2072621 Maybridge1_006156 Cc1onc(c1NC(=O)O/N=C(\N)/Cc2ccc(cc2)C(C)(C)C)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P19 compound treatment 912232.0 315000.0 0.45 906614.0 305000.0 0.43 0.6181 0.9997 1493707 Maybridge1_006157 COc1ccc(CCNC(=O)C(Sc2ccccc2N)c3ccccc3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P20 compound treatment 925337.0 328000.0 0.47 899604.0 298000.0 0.42 0.6243 0.9983 2072622 Maybridge1_006158 N/C(=N\OC(=O)C(Cl)Cl)/c1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P21 compound treatment 887320.0 290000.0 0.41 896396.0 295000.0 0.41 0.583 1.0 2072623 Maybridge1_006159 Sc1nnc([nH]1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P22 compound treatment 891795.0 295000.0 0.42 882227.0 281000.0 0.39 0.5735 0.9994 2072624 Maybridge1_006160 Clc1ccc(/N=C/2\SCC(=O)N2C(=O)c3ccccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P23 mock treatment 880490.0 284000.0 0.4 866644.0 265000.0 0.37 0.5467 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.558 P24 mock treatment 241106.0 -356000.0 -0.51 285541.0 -316000.0 -0.44 -0.6693 -0.9976 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A01 compound treatment 804109.0 269000.0 0.38 818761.0 220000.0 0.31 0.4869 0.994 2072625 Maybridge1_006161 Fc1cccc(F)c1C(=O)NC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A02 compound treatment 815752.0 280000.0 0.4 800104.0 201000.0 0.28 0.4802 0.9851 2072626 Maybridge1_006162 COC(=O)c1ccc(OCC(F)(F)F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A03 compound treatment 800323.0 265000.0 0.38 823720.0 225000.0 0.31 0.488 0.9958 1461450 Maybridge1_006163 COC(=O)c1cc(=O)nc(N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A04 compound treatment 816512.0 281000.0 0.4 824072.0 225000.0 0.31 0.5046 0.9928 2072627 Maybridge1_006164 CC1(C)ONC(=O)N(CCc2cccs2)C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A05 compound treatment 878128.0 343000.0 0.49 854685.0 256000.0 0.36 0.5968 0.9882 2072628 Maybridge1_006165 N/C(=N\OC(=O)Nc1ccccc1)/c2ccc(cc2)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A06 compound treatment 870449.0 335000.0 0.48 861003.0 262000.0 0.37 0.5953 0.9914 2072629 Maybridge1_006166 FC(F)(F)c1cccc(c1)C(=O)NNC(=O)C2c3ccccc3Oc4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A07 compound treatment 886057.0 351000.0 0.5 889444.0 290000.0 0.4 0.639 0.9947 1378127 Maybridge1_006167 COc1nc(N)nc(n1)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A08 compound treatment 906631.0 371000.0 0.53 872557.0 273000.0 0.38 0.643 0.9872 1110159 Maybridge1_006168 CC(=O)Nc1ccc(NC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A09 compound treatment 901358.0 366000.0 0.52 879104.0 280000.0 0.39 0.6442 0.99 2072630 Maybridge1_006169 CSc1nc(N)nc(n1)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A10 compound treatment 899880.0 365000.0 0.52 877809.0 279000.0 0.39 0.6414 0.9899 2072631 Maybridge1_006170 CCOC(=O)c1cnn(c1N)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A11 compound treatment 906282.0 371000.0 0.53 874176.0 275000.0 0.38 0.6443 0.9878 1652130 Maybridge1_006171 Cn1c(nc(N)nc1=O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A12 compound treatment 891415.0 356000.0 0.51 901301.0 302000.0 0.42 0.6561 0.9958 2072632 Maybridge1_006172 CN(C)/C=N\c1ccc2nnc(c3ccccc3)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A13 compound treatment 912311.0 377000.0 0.54 892650.0 294000.0 0.41 0.6686 0.9911 2072633 Maybridge1_006173 O=C1CNC(=S)N1CCCn2ccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A14 compound treatment 928361.0 393000.0 0.56 907824.0 309000.0 0.43 0.6997 0.9917 1083204 Maybridge1_006174 Cc1ccc2ncnc(O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A15 compound treatment 919030.0 384000.0 0.55 929872.0 331000.0 0.46 0.712 0.9965 2072634 Maybridge1_006175 Clc1ccc(CN2C(=O)CNC2=S)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A16 compound treatment 913078.0 378000.0 0.54 873496.0 274000.0 0.38 0.6505 0.9862 2072635 Maybridge1_006176 [O-][N+](=O)c1cccnc1NC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A17 compound treatment 923364.0 388000.0 0.55 907535.0 308000.0 0.43 0.6944 0.9924 1052429 Maybridge1_006177 COc1nc(N)nc(OC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A18 compound treatment 902976.0 368000.0 0.52 887172.0 288000.0 0.4 0.6538 0.9915 2072636 Maybridge1_006178 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NNC(=O)CSc2nc3cccnc3s2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A19 compound treatment 873070.0 338000.0 0.48 901342.0 302000.0 0.42 0.6377 0.9979 2072637 Maybridge1_006179 NC(=O)c1cnccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A20 compound treatment 852467.0 317000.0 0.45 871919.0 273000.0 0.38 0.5879 0.9964 1546171 Maybridge1_006180 Clc1ccc2c(Sc3nnc(NC(=O)c4cccnc4Oc5ccccc5)s3)ccnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A21 compound treatment 840454.0 305000.0 0.43 866279.0 267000.0 0.37 0.5703 0.9971 2072638 Maybridge1_006181 COc1cc(c(cn1)C(=O)N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A22 compound treatment 809883.0 275000.0 0.39 841399.0 242000.0 0.34 0.515 0.9974 1012003 Maybridge1_006182 COC(=O)c1cc(ccc1NC(=O)C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A23 mock treatment 799912.0 265000.0 0.38 827454.0 228000.0 0.32 0.4912 0.9966 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 A24 mock treatment 154196.0 -381000.0 -0.54 137348.0 -462000.0 -0.64 -0.8386 -0.9963 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B01 compound treatment 833332.0 298000.0 0.42 803915.0 205000.0 0.29 0.5016 0.9816 1304551 Maybridge1_006183 CCCCc1ccc(NC(=O)CSc2nc(c(o2)c3ccccc3)c4ccccc4)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B02 compound treatment 812123.0 277000.0 0.39 847016.0 248000.0 0.35 0.5228 0.9979 2072639 Maybridge1_006184 CCOC(=O)CNC(=O)CC(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B03 compound treatment 901762.0 366000.0 0.52 911457.0 312000.0 0.44 0.6765 0.996 2072640 Maybridge1_006185 CC(NCc1ccc(OCc2ccc(F)cc2)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B04 compound treatment 899244.0 364000.0 0.52 924080.0 325000.0 0.45 0.6864 0.9978 2072641 Maybridge1_006186 COc1ccc(cc1)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B05 compound treatment 950476.0 415000.0 0.59 932081.0 333000.0 0.46 0.7458 0.9929 1600962 Maybridge1_006187 COc1ccc(cc1)N(Cc2ccccc2)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B06 compound treatment 885212.0 350000.0 0.5 841590.0 242000.0 0.34 0.591 0.9823 2072642 Maybridge1_006188 COc1cc(N2CCCC2)c(cc1[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B07 compound treatment 945822.0 410000.0 0.58 937011.0 338000.0 0.47 0.746 0.9944 1280583 Maybridge1_006189 Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B08 compound treatment 892494.0 357000.0 0.51 912370.0 313000.0 0.44 0.6681 0.9972 2072643 Maybridge1_006190 CCOC(=O)c1cc2cc(F)ccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B09 compound treatment 961703.0 426000.0 0.61 940358.0 341000.0 0.48 0.7653 0.9928 2072644 Maybridge1_006191 COc1ccc(c(OC)c1)S(=O)(=O)Nc2cc(C)c(C)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B10 compound treatment 917589.0 382000.0 0.54 934996.0 336000.0 0.47 0.7156 0.9973 1648563 Maybridge1_006192 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B11 compound treatment 946479.0 411000.0 0.58 918995.0 320000.0 0.45 0.7289 0.9911 2072645 Maybridge1_006193 CCCCCOc1ccc(cc1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B12 compound treatment 933522.0 398000.0 0.57 928138.0 329000.0 0.46 0.7249 0.9946 2072646 Maybridge1_006194 CCCCCCCCCCCCCCCCCCN1CNC(=S)NC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B13 compound treatment 971076.0 436000.0 0.62 984240.0 385000.0 0.54 0.818 0.9975 1044813 Maybridge1_006195 Brc1ccc2[nH]ccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B14 compound treatment 940661.0 405000.0 0.58 927327.0 328000.0 0.46 0.7313 0.9935 2072647 Maybridge1_006196 Nc1nc(cs1)c2ccc(Cl)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B15 compound treatment 992362.0 457000.0 0.65 883713.0 285000.0 0.4 0.7403 0.972 1089306 Maybridge1_006197 COC(=O)CNCC(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B16 compound treatment 931299.0 396000.0 0.56 935368.0 336000.0 0.47 0.7298 0.9959 1008328 Maybridge1_006198 CC(=O)Nc1ccc(OC(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B17 compound treatment 991231.0 456000.0 0.65 980601.0 381000.0 0.53 0.8347 0.9952 1371751 Maybridge1_006199 Cc1cc(Nc2ccccc2C(=O)O)n(n1)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B18 compound treatment 867307.0 332000.0 0.47 870284.0 271000.0 0.38 0.6013 0.994 1238043 Maybridge1_006200 Fc1cccc(Cl)c1C(=O)Nc2cccc(c2)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B19 compound treatment 937566.0 402000.0 0.57 971514.0 372000.0 0.52 0.7717 0.9988 1685353 Maybridge1_006201 COC(=O)c1[nH]c2ccccc2c1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B20 compound treatment 873757.0 338000.0 0.48 921206.0 322000.0 0.45 0.658 0.9994 2072648 Maybridge1_006202 Cc1cc(Sc2nnc(n2C)C(F)(F)F)c(cc1[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B21 compound treatment 915311.0 380000.0 0.54 953328.0 354000.0 0.49 0.7314 0.999 2072649 Maybridge1_006203 COc1ccc(Oc2ccc(cc2N)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B22 compound treatment 855428.0 320000.0 0.46 910847.0 312000.0 0.43 0.6293 0.9997 2072650 Maybridge1_006204 CCCCCCNC(=O)NCCCCCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B23 mock treatment 850282.0 315000.0 0.45 908046.0 309000.0 0.43 0.6214 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 B24 mock treatment 152572.0 -383000.0 -0.54 153473.0 -446000.0 -0.62 -0.8244 -0.9978 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C01 compound treatment 734894.0 200000.0 0.28 738778.0 140000.0 0.19 0.3384 0.9831 2072651 Maybridge1_006205 COC(=O)c1onc(c1C(=O)OC)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C02 compound treatment 745164.0 210000.0 0.3 781645.0 183000.0 0.25 0.391 0.9969 2072652 Maybridge1_006206 COC(=O)c1cc(OCC(F)(F)F)nc(OCC(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C03 compound treatment 788629.0 253000.0 0.36 845858.0 247000.0 0.34 0.4981 0.9997 1728994 Maybridge1_006207 CCOC(=O)c1sc(N)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C04 compound treatment 786189.0 251000.0 0.36 824804.0 226000.0 0.31 0.4748 0.9981 2072653 Maybridge1_006208 O=C1CS/C(=N/N=C/c2ccn[nH]2)/N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C05 compound treatment 792715.0 257000.0 0.37 817916.0 219000.0 0.31 0.4746 0.9959 2072654 Maybridge1_006209 N/C(=N\OC(=O)Nc1ccc(Cl)cc1)/c2ccc(cc2)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C06 compound treatment 742419.0 207000.0 0.29 844342.0 245000.0 0.34 0.4501 0.9972 2072655 Maybridge1_006210 [O-][N+](=O)c1cccc(c1)C(=O)NNC(=O)C2c3ccccc3Oc4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C07 compound treatment 830079.0 295000.0 0.42 860711.0 262000.0 0.36 0.5544 0.9976 2072656 Maybridge1_006211 CSc1nc(C)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C08 compound treatment 987844.0 453000.0 0.64 1011743.0 413000.0 0.58 0.862 0.9984 2072657 Maybridge1_006212 Nc1c(C#N)cnn1c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C09 compound treatment 859303.0 324000.0 0.46 858645.0 260000.0 0.36 0.5817 0.9929 1409063 Maybridge1_006213 CSc1nc(N)nc(n1)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C10 compound treatment 832994.0 298000.0 0.42 887751.0 289000.0 0.4 0.584 0.9997 1005947 Maybridge1_006214 OC(=O)CCC(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C11 compound treatment 831824.0 296000.0 0.42 850477.0 251000.0 0.35 0.546 0.9958 2072658 Maybridge1_006215 Cc1onc(c1C(=O)O/N=C(\N)/c2ccc(o2)[N+](=O)[O-])c3cccc(Cl)c3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C12 compound treatment 817964.0 283000.0 0.4 847009.0 248000.0 0.35 0.5287 0.9972 2072659 Maybridge1_006216 Sc1nc2cc(Cl)ccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C13 compound treatment 809318.0 274000.0 0.39 852640.0 254000.0 0.35 0.5255 0.9988 2072660 Maybridge1_006217 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C14 compound treatment 845325.0 310000.0 0.44 862372.0 263000.0 0.37 0.5713 0.9959 2072661 Maybridge1_006218 COC(=O)C(C)(C)Oc1ccc(C)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C15 compound treatment 842802.0 307000.0 0.44 919564.0 320000.0 0.45 0.6252 0.9999 1222937 Maybridge1_006219 COc1ccc(CN2C(=O)CNC2=S)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C16 compound treatment 843103.0 308000.0 0.44 882848.0 284000.0 0.4 0.5893 0.9987 2072662 Maybridge1_006220 CS(=O)(=O)OCCN1CCN(CC1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C17 compound treatment 867080.0 332000.0 0.47 890756.0 292000.0 0.41 0.6212 0.9973 2072663 Maybridge1_006221 CSC1=N/C(=C\N(C)C)/C(=O)N1CCOc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C18 compound treatment 818185.0 283000.0 0.4 851979.0 253000.0 0.35 0.5338 0.9979 2072664 Maybridge1_006222 COC(=O)C(C(=O)OC)c1ccc(Cl)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C19 compound treatment 835632.0 300000.0 0.43 908294.0 309000.0 0.43 0.6069 1.0 2072665 Maybridge1_006223 OC1c2ccnn2[C@@H](O)c3ccnn13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C20 compound treatment 748678.0 213000.0 0.3 801565.0 202000.0 0.28 0.4142 0.9994 1038600 Maybridge1_006224 [O-][N+](=O)c1ccc2NCCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C21 compound treatment 810228.0 275000.0 0.39 907006.0 308000.0 0.43 0.5801 0.9989 2072666 Maybridge1_006225 CC(C)(C)C(=O)OC/C(=N/OC(=O)c1cccs1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C22 compound treatment 767103.0 232000.0 0.33 841217.0 242000.0 0.34 0.4718 0.9999 1918351 Maybridge1_006226 Oc1ccc2ccccc2c1C(/N=C/c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C23 mock treatment 770555.0 235000.0 0.33 852580.0 253000.0 0.35 0.4865 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 C24 mock treatment 147176.0 -388000.0 -0.55 159990.0 -439000.0 -0.61 -0.8234 -0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D01 compound treatment 862110.0 327000.0 0.46 822352.0 223000.0 0.31 0.5488 0.981 2072667 Maybridge1_006227 COC(=O)c1ccccc1CSc2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D02 compound treatment 818560.0 283000.0 0.4 870395.0 271000.0 0.38 0.5523 0.9995 2072668 Maybridge1_006228 NC(=O)CSc1ccc(cn1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D03 compound treatment 928183.0 393000.0 0.56 937856.0 339000.0 0.47 0.7291 0.9965 1381669 Maybridge1_006229 CCOC(=O)COc1ccc(C)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D04 compound treatment 909705.0 374000.0 0.53 901888.0 303000.0 0.42 0.6751 0.9934 2072669 Maybridge1_006230 c1sc(nc1c2ccccc2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D05 compound treatment 948748.0 413000.0 0.59 945331.0 346000.0 0.48 0.7572 0.9952 2072670 Maybridge1_006231 Fc1ccc(OCc2ccccc2)c(c1)C(=O)CCc3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D06 compound treatment 921486.0 386000.0 0.55 936510.0 337000.0 0.47 0.721 0.997 2072671 Maybridge1_006232 CCOC(=O)C(Cc1ccc(F)cc1)(NC(=O)C)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D07 compound treatment 983277.0 448000.0 0.64 972414.0 373000.0 0.52 0.8186 0.995 2072672 Maybridge1_006233 C(Cc1ccccc1)/N=C/c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D08 compound treatment 948683.0 413000.0 0.59 956170.0 357000.0 0.5 0.7678 0.9966 2072673 Maybridge1_006234 CCCCCC(=O)Nc1nc-2c(CCc3cc(OC)ccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D09 compound treatment 972963.0 438000.0 0.62 962172.0 363000.0 0.51 0.7981 0.9948 1250582 Maybridge1_006235 Cc1ccc(COc2c(c3ccccc3)c(=O)n4CCCc5cc(C)cc2c54)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D10 compound treatment 971133.0 436000.0 0.62 931469.0 332000.0 0.46 0.766 0.9898 2072674 Maybridge1_006236 COc1ccc2-c3nc(N/C=N/O)sc3CCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D11 compound treatment 952991.0 418000.0 0.59 964517.0 365000.0 0.51 0.7804 0.9971 1077542 Maybridge1_006237 C1Cc2ccccc2-c3[nH]c4ccccc4c13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D12 compound treatment 894959.0 360000.0 0.51 916580.0 317000.0 0.44 0.6747 0.9974 1021563 Maybridge1_006238 CCc1c(C)[nH]c2ccc(cc12)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D13 compound treatment 936937.0 402000.0 0.57 988492.0 389000.0 0.54 0.7879 0.9997 1561441 Maybridge1_006239 CC(=O)Nc1ccc(cc1)c2cc(C(=O)O)c3ccccc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D14 compound treatment 970957.0 436000.0 0.62 1017844.0 419000.0 0.58 0.851 0.9996 2072675 Maybridge1_006240 FC(F)(F)c1cccc(c1)N2CCCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D15 compound treatment 1017650.0 482000.0 0.69 1023942.0 425000.0 0.59 0.904 0.9973 1509391 Maybridge1_006241 OC(=O)CC(CC(=O)O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D16 compound treatment 979656.0 444000.0 0.63 983958.0 385000.0 0.54 0.8263 0.9967 1177095 Maybridge1_006242 Cc1cc(O)cc2OC(C)(C)CC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D17 compound treatment 1011945.0 477000.0 0.68 997540.0 398000.0 0.56 0.8722 0.9951 1384385 Maybridge1_006243 Clc1cc(Cl)c2cccnc2c1OC(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D18 compound treatment 961320.0 426000.0 0.61 969525.0 370000.0 0.52 0.7937 0.9969 2072676 Maybridge1_006244 [O-][N+](=O)c1cc(ccc1Sc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D19 compound treatment 974397.0 439000.0 0.62 1019036.0 420000.0 0.59 0.8556 0.9995 2072677 Maybridge1_006245 CCOC(=O)Cc1ccccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D20 compound treatment 911655.0 376000.0 0.54 991466.0 392000.0 0.55 0.7654 0.9999 2072678 Maybridge1_006246 Cn1c(Sc2c(cc(cc2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D21 compound treatment 963488.0 428000.0 0.61 1004210.0 405000.0 0.56 0.8301 0.9993 2072679 Maybridge1_006247 N/N=C/1\C(=O)Nc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D22 compound treatment 871991.0 337000.0 0.48 945284.0 346000.0 0.48 0.6799 1.0 2072680 Maybridge1_006248 COc1ccccc1C2CCN(CC2)C(=O)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D23 mock treatment 929417.0 394000.0 0.56 990651.0 392000.0 0.55 0.7824 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 D24 mock treatment 156543.0 -379000.0 -0.54 173589.0 -426000.0 -0.59 -0.8005 -0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E01 compound treatment 830951.0 296000.0 0.42 826839.0 228000.0 0.32 0.5219 0.9904 2072681 Maybridge1_006249 Clc1cccc(Cl)c1c2nsc(=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E02 compound treatment 818595.0 283000.0 0.4 913485.0 314000.0 0.44 0.5949 0.9991 2072682 Maybridge1_006250 NC(=O)c1ccc(OCC(F)(F)F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E03 compound treatment 878999.0 344000.0 0.49 968795.0 370000.0 0.52 0.7102 0.9996 1004151 Maybridge1_006251 NC(=O)c1ccc(o1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E04 compound treatment 902175.0 367000.0 0.52 968368.0 369000.0 0.51 0.7331 1.0 1031001 Maybridge1_006252 Oc1ccccc1C(=O)CC(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E05 compound treatment 959735.0 424000.0 0.6 1024920.0 426000.0 0.59 0.8467 1.0 2072683 Maybridge1_006253 NC(=S)c1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E06 compound treatment 973071.0 438000.0 0.62 1027909.0 429000.0 0.6 0.8631 0.9998 1735704 Maybridge1_006254 O=c1[nH]c2c(C#N)cnn2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E07 compound treatment 954723.0 419000.0 0.6 966748.0 368000.0 0.51 0.7843 0.9972 2072684 Maybridge1_006255 CSc1nc(N)nc(n1)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E08 compound treatment 1019972.0 485000.0 0.69 1036817.0 438000.0 0.61 0.919 0.9982 1419577 Maybridge1_006256 Oc1c(c2ccccc2)c(=O)n3c4CCCCc4c5cccc1c53 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E09 compound treatment 970889.0 436000.0 0.62 1002604.0 403000.0 0.56 0.8359 0.9989 1301788 Maybridge1_006257 CSc1nc(N)nc(n1)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E10 compound treatment 963468.0 428000.0 0.61 1002208.0 403000.0 0.56 0.8281 0.9992 2072685 Maybridge1_006258 CCOC(=O)c1ccc2nc(/N=C/N(C)C)sc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E11 compound treatment 939864.0 405000.0 0.58 1020565.0 421000.0 0.59 0.8224 0.9999 2072686 Maybridge1_006259 Cc1nc(N)nc(N/N=C/c2ccccc2O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E12 compound treatment 952117.0 417000.0 0.59 1016154.0 417000.0 0.58 0.8304 1.0 2072687 Maybridge1_006260 Oc1ncnc2ccc(Br)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E13 compound treatment 961846.0 427000.0 0.61 1016825.0 418000.0 0.58 0.8408 0.9998 2072688 Maybridge1_006261 FC(F)(F)C(=O)NNC(=O)c1ccc[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E14 compound treatment 958020.0 423000.0 0.6 1012380.0 413000.0 0.58 0.8326 0.9998 2072689 Maybridge1_006262 Cc1ccc2ncnc(Oc3ncccc3[N+](=O)[O-])c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E15 compound treatment 1025715.0 490000.0 0.7 1098481.0 499000.0 0.7 0.9856 1.0 2072690 Maybridge1_006263 Clc1cccc(CN2C(=O)CNC2=S)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E16 compound treatment 961138.0 426000.0 0.61 987288.0 388000.0 0.54 0.811 0.9984 2072691 Maybridge1_006264 CCOC(=O)c1cnn(c1N)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E17 compound treatment 992535.0 457000.0 0.65 1032129.0 433000.0 0.6 0.8868 0.9993 1330771 Maybridge1_006265 CC(C)NC(=O)N(Cc1cccnc1)Cc2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E18 compound treatment 953263.0 418000.0 0.59 1012475.0 413000.0 0.58 0.8279 0.9999 2072692 Maybridge1_006266 COc1ccc2[nH]c(S)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E19 compound treatment 938366.0 403000.0 0.57 1014432.0 415000.0 0.58 0.8149 1.0 2072693 Maybridge1_006267 OC(=O)c1cnccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E20 compound treatment 931335.0 396000.0 0.56 1005778.0 407000.0 0.57 0.7993 1.0 1049568 Maybridge1_006268 CC(=O)N1CCc2cc(ccc12)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E21 compound treatment 911724.0 376000.0 0.54 1036716.0 438000.0 0.61 0.8101 0.9979 2072694 Maybridge1_006269 CCOC(=O)c1csc(n1)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E22 compound treatment 867860.0 333000.0 0.47 999553.0 400000.0 0.56 0.7293 0.9966 2072695 Maybridge1_006270 Oc1ccc2ccccc2c1C(/N=C/c3ccc(cc3)C(F)(F)F)c4ccc(cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E23 mock treatment 884182.0 349000.0 0.5 984520.0 385000.0 0.54 0.7309 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 E24 mock treatment 140994.0 -394000.0 -0.56 153358.0 -446000.0 -0.62 -0.8361 -0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F01 compound treatment 864209.0 329000.0 0.47 818608.0 219000.0 0.31 0.5472 0.9789 2072696 Maybridge1_006271 Cc1ccc(cc1)C(=O)c2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F02 compound treatment 906725.0 371000.0 0.53 884005.0 285000.0 0.4 0.6544 0.9902 1667943 Maybridge1_006272 OC(=O)CCNc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F03 compound treatment 942856.0 408000.0 0.58 969097.0 370000.0 0.52 0.7747 0.9983 1351203 Maybridge1_006273 CCOC(=O)COc1cccc2c(C)cc(=O)oc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F04 compound treatment 955564.0 420000.0 0.6 976960.0 378000.0 0.53 0.7952 0.998 1028837 Maybridge1_006274 OC1(Cc2ccccn2)C(=O)Nc3ccccc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F05 compound treatment 988279.0 453000.0 0.64 936355.0 337000.0 0.47 0.7881 0.9881 2072697 Maybridge1_006275 CC(=O)c1ccc(OCc2ccccc2)cc1OCc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F06 compound treatment 981797.0 446000.0 0.63 948403.0 349000.0 0.49 0.7934 0.9914 2072698 Maybridge1_006276 CCOC(=O)CC1=Nn2c(nnc2SC1)c3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F07 compound treatment 956919.0 422000.0 0.6 954884.0 356000.0 0.5 0.7748 0.9956 2072699 Maybridge1_006277 Cc1cc(ccc1[N+](=O)[O-])C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F08 compound treatment 985384.0 450000.0 0.64 965279.0 366000.0 0.51 0.8137 0.9937 1044908 Maybridge1_006278 CCOC(=O)c1cnn(c1N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F09 compound treatment 1008585.0 473000.0 0.67 1002688.0 404000.0 0.56 0.8739 0.9961 2072700 Maybridge1_006279 CCCCCc1ccc(cc1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F10 compound treatment 974495.0 439000.0 0.62 981308.0 382000.0 0.53 0.8185 0.9969 2072701 Maybridge1_006280 O/N=C/Nc1nc-2c(CCc3ccccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F11 compound treatment 956171.0 421000.0 0.6 997850.0 399000.0 0.56 0.8164 0.9993 1060684 Maybridge1_006281 C1CCCc2c(CC1)[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F12 compound treatment 969096.0 434000.0 0.62 1021582.0 422000.0 0.59 0.8528 0.9997 2072702 Maybridge1_006282 COc1ccc2-c3nc(/N=C/c4ccc(cc4)C(F)(F)F)sc3CCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F13 compound treatment 990580.0 455000.0 0.65 1008973.0 410000.0 0.57 0.862 0.9981 1049405 Maybridge1_006283 CS(=O)(=O)c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F14 compound treatment 987218.0 452000.0 0.64 1006712.0 408000.0 0.57 0.8564 0.9981 2072703 Maybridge1_006284 C1Oc2ccc(/C=N/c3nc-4c(CCc5ccccc45)s3)cc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F15 compound treatment 974436.0 439000.0 0.62 1036750.0 438000.0 0.61 0.8732 0.9999 2072704 Maybridge1_006285 Clc1ccc(cc1)C2CC(=O)NC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F16 compound treatment 954157.0 419000.0 0.6 1014551.0 415000.0 0.58 0.8309 0.9999 2072705 Maybridge1_006286 COc1ccc(C)nc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F17 compound treatment 1004345.0 469000.0 0.67 1045438.0 446000.0 0.62 0.9118 0.9994 2072706 Maybridge1_006287 OC(=O)c1cc(ccc1Sc2ccc(cc2C(=O)O)[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F18 compound treatment 932035.0 397000.0 0.56 923620.0 325000.0 0.45 0.7189 0.994 1620619 Maybridge1_006288 Cc1c(OCc2ccccc2F)ccc3C(=O)CC(C)(C)Oc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F19 compound treatment 981418.0 446000.0 0.63 1046776.0 448000.0 0.62 0.8901 1.0 1102313 Maybridge1_006289 Clc1cc2nc[nH]c2cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F20 compound treatment 981478.0 446000.0 0.63 999273.0 400000.0 0.56 0.8433 0.998 2072707 Maybridge1_006290 CC(=O)COc1ccc2C(=O)CC(C)(C)Oc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F21 compound treatment 996963.0 462000.0 0.66 1044963.0 446000.0 0.62 0.9039 0.9996 1017701 Maybridge1_006291 CSc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F22 compound treatment 898782.0 363000.0 0.52 969038.0 370000.0 0.52 0.7303 1.0 1781380 Maybridge1_006292 COc1ccccc1N2CCN(CC2)C(=O)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F23 mock treatment 936520.0 401000.0 0.57 1004576.0 405000.0 0.57 0.8033 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 F24 mock treatment 174553.0 -361000.0 -0.51 152771.0 -446000.0 -0.62 -0.803 -0.9954 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G01 compound treatment 812342.0 277000.0 0.39 810568.0 211000.0 0.29 0.4871 0.9898 2072708 Maybridge1_006293 NC(=N)C1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G02 compound treatment 833641.0 298000.0 0.42 849392.0 250000.0 0.35 0.5468 0.9953 2072709 Maybridge1_006294 OC(=O)c1cc(OCC(F)(F)F)nc(OCC(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G03 compound treatment 903948.0 369000.0 0.52 970811.0 372000.0 0.52 0.7372 1.0 1166265 Maybridge1_006295 CC(C)c1ccc(Nc2snc(O)c2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G04 compound treatment 859516.0 324000.0 0.46 961971.0 363000.0 0.51 0.6838 0.9989 2072710 Maybridge1_006296 CC(=O)c1ccccc1OC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G05 compound treatment 936246.0 401000.0 0.57 971104.0 372000.0 0.52 0.77 0.9989 2072711 Maybridge1_006297 Clc1ccc(N2C(=N)SCC2=O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G06 compound treatment 841304.0 306000.0 0.44 948534.0 349000.0 0.49 0.6523 0.9984 2072712 Maybridge1_006298 Cc1[nH]c(=O)[nH]c(=O)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G07 compound treatment 924407.0 389000.0 0.55 956198.0 357000.0 0.5 0.7434 0.9986 1556343 Maybridge1_006299 CSc1nc(N)nc(n1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G08 compound treatment 920125.0 385000.0 0.55 937310.0 338000.0 0.47 0.7205 0.9973 2072713 Maybridge1_006300 NC(=O)c1cnn(c1N)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G09 compound treatment 903864.0 369000.0 0.52 974652.0 376000.0 0.52 0.7409 1.0 2072714 Maybridge1_006301 CCCCNC(=O)NS(=O)(=O)c1ccccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G10 compound treatment 927354.0 392000.0 0.56 974820.0 376000.0 0.52 0.7647 0.9995 2072715 Maybridge1_006302 CCOC(=O)/C(=C/Nc1nc2ccc(cc2s1)C(=O)OCC)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G11 compound treatment 943132.0 408000.0 0.58 1020404.0 421000.0 0.59 0.8256 1.0 2072716 Maybridge1_006303 CC(C)(C)C(=O)OCC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G12 compound treatment 931083.0 396000.0 0.56 968892.0 370000.0 0.52 0.7626 0.999 1030016 Maybridge1_006304 Oc1ncnc2cc(Cl)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G13 compound treatment 920495.0 385000.0 0.55 976556.0 377000.0 0.53 0.7595 0.9998 1714880 Maybridge1_006305 O=C1CNC(=S)N1Cc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G14 compound treatment 908954.0 374000.0 0.53 942047.0 343000.0 0.48 0.7139 0.9986 2072717 Maybridge1_006306 CC(C)(C)c1ccc(cc1)c2ncc(s2)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G15 compound treatment 944785.0 409000.0 0.58 1001461.0 402000.0 0.56 0.8085 0.9998 1083878 Maybridge1_006307 Clc1ccc(OCC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G16 compound treatment 932486.0 397000.0 0.56 990804.0 392000.0 0.55 0.7857 0.9999 2072718 Maybridge1_006308 CCOC(=O)c1cnn(c1n2cccc2)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G17 compound treatment 998975.0 464000.0 0.66 1052172.0 453000.0 0.63 0.913 0.9998 2072719 Maybridge1_006309 CSC1=NCC(=O)N1CCc2c[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G18 compound treatment 866232.0 331000.0 0.47 925576.0 326000.0 0.46 0.6547 0.9999 1666680 Maybridge1_006310 CCOC(=O)c1cc(=O)c2ccc(OC(=O)c3sc4ccccc4c3Cl)cc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G19 compound treatment 947826.0 413000.0 0.59 1008268.0 409000.0 0.57 0.8183 0.9999 2072720 Maybridge1_006311 NC(=O)C1=CNCCC1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G20 compound treatment 875532.0 340000.0 0.48 991618.0 393000.0 0.55 0.7292 0.9981 2072721 Maybridge1_006312 [O-][N+](=O)c1ccc2N(CCc2c1)C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G21 compound treatment 879103.0 344000.0 0.49 926926.0 328000.0 0.46 0.669 0.9994 2072722 Maybridge1_006313 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nc(CSc3ncccn3)no2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G22 compound treatment 874565.0 339000.0 0.48 980282.0 381000.0 0.53 0.717 0.9988 1603340 Maybridge1_006314 Oc1cc(=O)n2CCc3cccc1c32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G23 mock treatment 860459.0 325000.0 0.46 984400.0 385000.0 0.54 0.7069 0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 G24 mock treatment 147103.0 -388000.0 -0.55 161163.0 -438000.0 -0.61 -0.8223 -0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H01 compound treatment 871919.0 337000.0 0.48 835524.0 236000.0 0.33 0.5716 0.9834 2072723 Maybridge1_006315 CSc1c(C#N)c(N)[nH]c(=S)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H02 compound treatment 868414.0 333000.0 0.47 842030.0 243000.0 0.34 0.5745 0.9865 2072724 Maybridge1_006316 Nc1ccc(cc1)c2nnc(Nc3ccccc3C(F)(F)F)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H03 compound treatment 925274.0 390000.0 0.55 936973.0 338000.0 0.47 0.7253 0.9967 2072725 Maybridge1_006317 CC(=O)c1cc(F)ccc1OCc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H04 compound treatment 922076.0 387000.0 0.55 908926.0 310000.0 0.43 0.6944 0.9929 1285144 Maybridge1_006318 OC1(Cc2ccncc2)C(=O)Nc3ccccc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H05 compound treatment 955252.0 420000.0 0.6 932874.0 334000.0 0.47 0.7514 0.9924 1112292 Maybridge1_006319 COc1ccc(Cl)cc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H06 compound treatment 882832.0 348000.0 0.49 917948.0 319000.0 0.44 0.6639 0.9986 2072726 Maybridge1_006320 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2nc-3c(CCc4ccccc34)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H07 compound treatment 979288.0 444000.0 0.63 941074.0 342000.0 0.48 0.7837 0.9904 2072727 Maybridge1_006321 OC(=O)C1CC(CC(C1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H08 compound treatment 924407.0 389000.0 0.55 962268.0 363000.0 0.51 0.7494 0.999 2072728 Maybridge1_006322 CN(C)/C=N/c1nc-2c(CCc3ccccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H09 compound treatment 939160.0 404000.0 0.57 985113.0 386000.0 0.54 0.7868 0.9995 1425686 Maybridge1_006323 CCCCn1c(=O)c(C)c(C)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H10 compound treatment 938594.0 403000.0 0.57 1014774.0 416000.0 0.58 0.8154 1.0 2072729 Maybridge1_006324 CC(C)/C=C/C1=CC2=C(C1)Cc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H11 compound treatment 951056.0 416000.0 0.59 963874.0 365000.0 0.51 0.7778 0.9972 1556202 Maybridge1_006325 C1CCCCCc2c(CCCC1)[nH]c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H12 compound treatment 938413.0 403000.0 0.57 984821.0 386000.0 0.54 0.7857 0.9995 2072730 Maybridge1_006326 S=C1NCN(CCCCc2ccccc2)CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H13 compound treatment 879792.0 344000.0 0.49 960603.0 361000.0 0.5 0.7029 0.9999 2072731 Maybridge1_006327 [O-][N+](=O)/C=C/c1cc2OCOc2cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H14 compound treatment 930374.0 395000.0 0.56 954723.0 356000.0 0.5 0.7479 0.9981 1266526 Maybridge1_006328 Cc1ccc(cc1)S(=O)(=O)c2ccc(Cl)c(N)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H15 compound treatment 964172.0 429000.0 0.61 982537.0 383000.0 0.53 0.8094 0.9979 1053450 Maybridge1_006329 Cc1ccc2[nH]c3CCCCc3c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H16 compound treatment 912931.0 378000.0 0.54 975893.0 377000.0 0.53 0.7513 0.9999 2072732 Maybridge1_006330 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2cccc(c2)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H17 compound treatment 986552.0 451000.0 0.64 981538.0 382000.0 0.53 0.8309 0.9958 1411302 Maybridge1_006331 COC(=O)COc1c(Br)cc(Br)cc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H18 compound treatment 933260.0 398000.0 0.57 954780.0 356000.0 0.5 0.7509 0.9978 2072733 Maybridge1_006332 Cc1c(OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc3C(=O)CC(C)(C)Oc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H19 compound treatment 974565.0 439000.0 0.62 1039206.0 440000.0 0.61 0.8757 1.0 2072734 Maybridge1_006333 Clc1ccc2C(=O)N(Cc3ccccc3)C(=O)c4cccc1c42 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H20 compound treatment 878048.0 343000.0 0.49 976143.0 377000.0 0.53 0.7165 0.9993 2072735 Maybridge1_006334 Cn1c(Sc2ccc(cn2)[N+](=O)[O-])nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H21 compound treatment 948804.0 413000.0 0.59 1023399.0 424000.0 0.59 0.8342 1.0 2072736 Maybridge1_006335 CC(C)(C)c1ccc(cc1)C(=O)NNC(=O)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H22 compound treatment 4.784636E7 4.73E7 67.28 5.1826872E7 5.12E7 71.45 98.0954 0.9995 1015808 Maybridge1_006336 Cc1cc2nc3c(=O)[nH]c(=O)nc3n(CC(O)C(O)C(O)CO)c2cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H23 mock treatment 909697.0 374000.0 0.53 990357.0 391000.0 0.55 0.7623 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 H24 mock treatment 160797.0 -375000.0 -0.53 171002.0 -428000.0 -0.6 -0.7988 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I01 compound treatment 813992.0 279000.0 0.4 815237.0 216000.0 0.3 0.4934 0.9909 1681466 Maybridge1_006337 Cc1cc(O)nc(n1)C2(CC3CC4CC(C3)C2)C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I02 compound treatment 823474.0 288000.0 0.41 870802.0 272000.0 0.38 0.5577 0.9992 2072737 Maybridge1_006338 FC(F)(F)c1ccc[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I03 compound treatment 874612.0 339000.0 0.48 973140.0 374000.0 0.52 0.71 0.9992 2072738 Maybridge1_006339 Oc1nsc(Nc2ccccc2C(F)(F)F)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I04 compound treatment 868898.0 334000.0 0.47 959324.0 360000.0 0.5 0.6907 0.9996 1040552 Maybridge1_006340 OC(=O)C1c2ccccc2Oc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I05 compound treatment 930706.0 395000.0 0.56 974860.0 376000.0 0.52 0.7681 0.9994 2072739 Maybridge1_006341 Fc1ccc(cc1Cl)N2C(=N)SCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I06 compound treatment 913812.0 378000.0 0.54 914790.0 316000.0 0.44 0.6919 0.995 1033843 Maybridge1_006342 O=C1CCC(=NN1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I07 compound treatment 935757.0 400000.0 0.57 973385.0 374000.0 0.52 0.7718 0.9991 2072740 Maybridge1_006343 CSc1nc(N)nc(n1)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I08 compound treatment 893253.0 358000.0 0.51 864046.0 265000.0 0.37 0.6212 0.9876 1335096 Maybridge1_006344 CCC(=O)Nc1ccc(OC)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I09 compound treatment 938485.0 403000.0 0.57 993464.0 394000.0 0.55 0.7943 0.9998 1713393 Maybridge1_006345 CSc1nc(N)nc(n1)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I10 compound treatment 929238.0 394000.0 0.56 959077.0 360000.0 0.5 0.7511 0.9985 2072741 Maybridge1_006346 CCOC(=O)c1ccc2nc(sc2c1)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I11 compound treatment 939279.0 404000.0 0.57 970596.0 371000.0 0.52 0.7726 0.9987 2072742 Maybridge1_006347 CC(C)(C)C(=O)OC/C(=N/OC(=O)c1ccccc1)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I12 compound treatment 928245.0 393000.0 0.56 985657.0 387000.0 0.54 0.7763 0.9998 1189503 Maybridge1_006348 NC(=O)c1cccnc1Oc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I13 compound treatment 899905.0 365000.0 0.52 999449.0 400000.0 0.56 0.7614 0.9993 1373573 Maybridge1_006349 O=C1CNC(=S)N1Cc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I14 compound treatment 916666.0 381000.0 0.54 1011510.0 412000.0 0.58 0.7902 0.9996 1032780 Maybridge1_006350 COC(=O)COc1ccc(cc1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I15 compound treatment 940716.0 405000.0 0.58 968863.0 370000.0 0.52 0.7723 0.9985 2072743 Maybridge1_006351 Cc1cc(NCc2cccc(Cl)c2Cl)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I16 compound treatment 787992.0 253000.0 0.36 836892.0 238000.0 0.33 0.4886 0.9992 2072744 Maybridge1_006352 CN(C)/C=C/c1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I17 compound treatment 951553.0 416000.0 0.59 1000765.0 402000.0 0.56 0.8147 0.9996 1331627 Maybridge1_006353 COC(=O)c1cc(Cl)cc2SS(=O)Nc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I18 compound treatment 887890.0 353000.0 0.5 991485.0 392000.0 0.55 0.7415 0.999 1524120 Maybridge1_006354 CCOC(=O)c1cc(=O)c2ccc(OC(=O)c3cccnc3Oc4ccccc4)cc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I19 compound treatment 929336.0 394000.0 0.56 961532.0 362000.0 0.51 0.7536 0.9987 2072745 Maybridge1_006355 FC(F)(F)c1ccncc1C(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I20 compound treatment 929514.0 394000.0 0.56 1002885.0 404000.0 0.56 0.7946 1.0 2072746 Maybridge1_006356 CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)c(C)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I21 compound treatment 929442.0 394000.0 0.56 1026893.0 428000.0 0.6 0.8182 0.9995 2072747 Maybridge1_006357 COC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I22 compound treatment 843243.0 308000.0 0.44 961455.0 362000.0 0.51 0.667 0.9975 2072748 Maybridge1_006358 O=C/1/C(=C/c2ccccc2)/CCC\C1=C/c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I23 mock treatment 893220.0 358000.0 0.51 991007.0 392000.0 0.55 0.7464 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 I24 mock treatment 147731.0 -388000.0 -0.55 157129.0 -442000.0 -0.62 -0.8256 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J01 compound treatment 856004.0 321000.0 0.46 812048.0 213000.0 0.3 0.5325 0.9784 2072749 Maybridge1_006359 COc1ccc([N+](=O)[O-])c(SC(C)C(=O)O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J02 compound treatment 874027.0 339000.0 0.48 903341.0 304000.0 0.42 0.6406 0.998 2072750 Maybridge1_006360 Cc1ccc(OCC(=O)NNC(=O)NC(=O)c2ccccc2Cl)c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J03 compound treatment 941697.0 406000.0 0.58 964431.0 365000.0 0.51 0.7689 0.998 1463171 Maybridge1_006361 Cc1ccc(OCC(=O)NN)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J04 compound treatment 902210.0 367000.0 0.52 901560.0 302000.0 0.42 0.6672 0.9944 1712700 Maybridge1_006362 OC1(Cc2ccccn2)C(=O)Nc3ccc(Br)cc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J05 compound treatment 946499.0 411000.0 0.58 935720.0 337000.0 0.47 0.7454 0.9941 1158376 Maybridge1_006363 O=C(C(C(=O)N1CCc2ccccc12)c3ccccc3)N4CCc5ccccc45 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J06 compound treatment 921469.0 386000.0 0.55 945756.0 347000.0 0.48 0.7302 0.998 2072751 Maybridge1_006364 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2nc-3c(Cc4ccccc34)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J07 compound treatment 937410.0 402000.0 0.57 983789.0 385000.0 0.54 0.7837 0.9995 1201826 Maybridge1_006365 CCOC(=O)C1=C(C)NC(=S)NC1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J08 compound treatment 925611.0 390000.0 0.56 968029.0 369000.0 0.51 0.7563 0.9993 2072752 Maybridge1_006366 COc1ccc2-c3nc(/N=C/N(C)C)sc3CCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J09 compound treatment 969631.0 434000.0 0.62 1001356.0 402000.0 0.56 0.8334 0.9988 2072753 Maybridge1_006367 COC(=O)CSc1ncccc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J10 compound treatment 883972.0 349000.0 0.5 947147.0 348000.0 0.49 0.6938 0.9999 1149514 Maybridge1_006368 O=C1CCCc2c1c3ccccc3n2Cc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J11 compound treatment 920581.0 385000.0 0.55 965956.0 367000.0 0.51 0.7492 0.9994 2072754 Maybridge1_006369 Brc1ccc2cc[nH]c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J12 compound treatment 948730.0 413000.0 0.59 999066.0 400000.0 0.56 0.8101 0.9997 1458567 Maybridge1_006370 OCc1cn(Cc2ccccc2)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J13 compound treatment 961291.0 426000.0 0.61 1024398.0 425000.0 0.59 0.8478 0.9999 2072755 Maybridge1_006371 Cc1cc(c[nH]c1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J14 compound treatment 888553.0 353000.0 0.5 922904.0 324000.0 0.45 0.6745 0.9986 1013983 Maybridge1_006372 CC1=NN(C(=O)C1)c2cccc(c2)S(=O)(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J15 compound treatment 941716.0 406000.0 0.58 1001772.0 403000.0 0.56 0.8058 0.9999 2072756 Maybridge1_006373 COC(=O)Cc1cc(OC)c(OC)cc1C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J16 compound treatment 914116.0 379000.0 0.54 938722.0 340000.0 0.47 0.7158 0.9979 1300508 Maybridge1_006374 Cc1c(O)ccc2C(=O)CC(C)(C)Oc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J17 compound treatment 937364.0 402000.0 0.57 1027714.0 429000.0 0.6 0.827 0.9998 2072757 Maybridge1_006375 OC(=O)c1ccccc1Sc2c(cc(cc2[N+](=O)[O-])[N+](=O)[O-])C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J18 compound treatment 896514.0 361000.0 0.51 1005790.0 407000.0 0.57 0.7643 0.9988 2072758 Maybridge1_006376 Cn1c(Sc2ncccc2[N+](=O)[O-])nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J19 compound treatment 889485.0 354000.0 0.5 986805.0 388000.0 0.54 0.7385 0.9994 1313637 Maybridge1_006377 S=C(NCc1ccco1)Nc2ccc3[nH]ccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J20 compound treatment 920151.0 385000.0 0.55 1012168.0 413000.0 0.58 0.7943 0.9997 1593978 Maybridge1_006378 COc1ccccc1C2CCN(CC2)C(=S)Nc3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J21 compound treatment 929971.0 395000.0 0.56 1062100.0 463000.0 0.65 0.8534 0.9976 2072759 Maybridge1_006379 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J22 compound treatment 872786.0 337000.0 0.48 910924.0 312000.0 0.43 0.6468 0.9988 2072760 Maybridge1_006380 COc1cc(CC/C(=N/O)/C)ccc1OCc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J23 mock treatment 909048.0 374000.0 0.53 947668.0 349000.0 0.49 0.7195 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 J24 mock treatment 144399.0 -391000.0 -0.56 152729.0 -446000.0 -0.62 -0.8333 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K01 compound treatment 828300.0 293000.0 0.42 818095.0 219000.0 0.31 0.5106 0.9883 1921895 Maybridge1_006381 NC(=S)NNC(=O)C1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K02 compound treatment 837858.0 303000.0 0.43 886243.0 287000.0 0.4 0.5874 0.9994 2072761 Maybridge1_006382 CC(C)(C)c1cc([nH]n1)C(=O)NNS(=O)(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K03 compound treatment 891325.0 356000.0 0.51 939983.0 341000.0 0.48 0.6941 0.9995 1272169 Maybridge1_006383 Cc1onc(c1NC(=O)SCc2c(Cl)cccc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K04 compound treatment 901206.0 366000.0 0.52 940185.0 341000.0 0.48 0.7043 0.999 2072762 Maybridge1_006384 CSc1nc(c2cccs2)c(C#N)c(=O)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K05 compound treatment 909594.0 374000.0 0.53 963008.0 364000.0 0.51 0.7352 0.9997 2072763 Maybridge1_006385 CC(C)(C)c1ccc(cc1)N2C(=N)SCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K06 compound treatment 849819.0 314000.0 0.45 932449.0 333000.0 0.46 0.645 0.9998 2072764 Maybridge1_006386 CCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K07 compound treatment 930088.0 395000.0 0.56 959563.0 360000.0 0.5 0.7524 0.9985 2072765 Maybridge1_006387 CSc1nc(N)nc(n1)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K08 compound treatment 884726.0 349000.0 0.5 956427.0 357000.0 0.5 0.7037 1.0 2072766 Maybridge1_006388 OC(=O)c1cnn2c1[nH]c(=O)c3ccccc32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K09 compound treatment 938905.0 404000.0 0.57 981907.0 383000.0 0.53 0.7833 0.9993 1238111 Maybridge1_006389 CC(C)(C)c1nc(N)nc(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K10 compound treatment 875524.0 340000.0 0.48 975499.0 376000.0 0.52 0.7133 0.9992 1653742 Maybridge1_006390 CCOC(=O)c1ccc2nc(NC(=O)c3ccc(F)c(Cl)c3)sc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K11 compound treatment 923540.0 388000.0 0.55 955933.0 357000.0 0.5 0.7423 0.9987 1025079 Maybridge1_006391 COC(=O)c1ccc(nc1)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K12 compound treatment 867665.0 332000.0 0.47 902276.0 303000.0 0.42 0.6332 0.9985 1391060 Maybridge1_006392 CCOC(=O)C1(O)C(=O)Nc2cc(OC)cc(OC)c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K13 compound treatment 917808.0 382000.0 0.54 1009712.0 411000.0 0.57 0.7895 0.9997 2072767 Maybridge1_006393 Clc1ccc(CCN2C(=O)CNC2=S)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K14 compound treatment 874090.0 339000.0 0.48 984752.0 386000.0 0.54 0.721 0.9985 2072768 Maybridge1_006394 CCOC(=O)COc1cccc(c1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K15 compound treatment 939809.0 404000.0 0.58 988147.0 389000.0 0.54 0.7904 0.9996 2072769 Maybridge1_006395 NC(=S)c1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K16 compound treatment 878231.0 343000.0 0.49 965792.0 367000.0 0.51 0.7064 0.9997 2072770 Maybridge1_006396 OC(=O)c1cc(ccc1F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K17 compound treatment 935620.0 400000.0 0.57 1019025.0 420000.0 0.59 0.8166 0.9999 1469361 Maybridge1_006397 O=C1CNC(=S)N1Cc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K18 compound treatment 909183.0 374000.0 0.53 944756.0 346000.0 0.48 0.7168 0.9988 2072771 Maybridge1_006398 CCCCCCCC(=O)Nc1nnc(Sc2ccnc3cc(Cl)ccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K19 compound treatment 904304.0 369000.0 0.52 1005988.0 407000.0 0.57 0.7723 0.9992 2072772 Maybridge1_006399 FC(F)(F)c1ccncc1C(=O)Nc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K20 compound treatment 852512.0 317000.0 0.45 956738.0 358000.0 0.5 0.6716 0.9987 1614406 Maybridge1_006400 Cc1c(O)c(ccc1OCc2ccc(Cl)c(Cl)c2)c3cc[nH]n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K21 compound treatment 886333.0 351000.0 0.5 953592.0 354000.0 0.49 0.7025 1.0 2072773 Maybridge1_006401 COC(=O)c1cc(I)c(OC(=O)C)c(I)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K22 compound treatment 866271.0 331000.0 0.47 936147.0 337000.0 0.47 0.6652 1.0 2072774 Maybridge1_006402 C1CCN(C1)C/23OC4=C(CCCC4)C(C3CCC\C2=C/c5ccccc5)c6ccccc6 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K23 mock treatment 871220.0 336000.0 0.48 992923.0 394000.0 0.55 0.7261 0.9976 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 K24 mock treatment 135095.0 -400000.0 -0.57 158031.0 -441000.0 -0.62 -0.8375 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L01 compound treatment 834671.0 299000.0 0.43 826633.0 228000.0 0.32 0.5254 0.9895 2072775 Maybridge1_006403 COc1cccc(CNC(C)C(=O)O)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L02 compound treatment 844482.0 309000.0 0.44 829494.0 230000.0 0.32 0.5381 0.9881 1528089 Maybridge1_006404 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC)cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L03 compound treatment 892065.0 357000.0 0.51 928540.0 329000.0 0.46 0.6836 0.9988 2072776 Maybridge1_006405 OC(=O)C(Cc1ccccc1)NCc2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L04 compound treatment 908320.0 373000.0 0.53 935032.0 336000.0 0.47 0.7064 0.9981 1684989 Maybridge1_006406 O=C(NCCc1ccccc1)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L05 compound treatment 921814.0 386000.0 0.55 953451.0 354000.0 0.49 0.7381 0.9986 1054407 Maybridge1_006407 O=C(Nc1ccccc1)C(C(=O)Nc2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L06 compound treatment 874462.0 339000.0 0.48 882469.0 283000.0 0.4 0.6205 0.9951 2072777 Maybridge1_006408 [O-][N+](=O)c1cccc2[nH]ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L07 compound treatment 890224.0 355000.0 0.5 908601.0 309000.0 0.43 0.6621 0.997 2072778 Maybridge1_006409 CCCCCCCCCCCC1SC[C@H](N1C(=O)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L08 compound treatment 911940.0 377000.0 0.54 949093.0 350000.0 0.49 0.7239 0.9989 2072779 Maybridge1_006410 C[C@@H](O[C@@H]1[C@@H](NC(=O)C)[C@@H](OCc2ccccc2)O[C@@H]3COC(O[C@@H]13)c4ccccc4)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L09 compound treatment 910513.0 375000.0 0.53 976772.0 378000.0 0.53 0.7497 1.0 2072780 Maybridge1_006411 OC(=O)c1[nH]c2ccc(cc2c1c3ccccc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L10 compound treatment 911122.0 376000.0 0.53 917616.0 319000.0 0.44 0.692 0.9958 1290636 Maybridge1_006412 CC1(C)CC(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L11 compound treatment 919538.0 384000.0 0.55 960306.0 361000.0 0.5 0.7426 0.9992 2072781 Maybridge1_006413 Cc1cc(OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)n(n1)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L12 compound treatment 873086.0 338000.0 0.48 934761.0 336000.0 0.47 0.6707 0.9999 1688823 Maybridge1_006414 OC(=O)Cc1csc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L13 compound treatment 870527.0 335000.0 0.48 1003543.0 404000.0 0.56 0.7359 0.9965 1037728 Maybridge1_006415 Brc1ccc2CCc3cccc1c32 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L14 compound treatment 897856.0 363000.0 0.52 948487.0 349000.0 0.49 0.7091 0.9996 1017937 Maybridge1_006416 CCOC(=O)Cc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L15 compound treatment 957118.0 422000.0 0.6 1202847.0 604000.0 0.84 1.0195 0.9862 2072782 Maybridge1_006417 C/C(=N\Nc1ccccc1)/c2cc3cc(Br)ccc3oc2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L16 compound treatment 898465.0 363000.0 0.52 960020.0 361000.0 0.5 0.7211 0.9999 1595740 Maybridge1_006418 CCCCc1ccc(NC(=S)N2CCC(CC2)C(=O)OCC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L17 compound treatment 906231.0 371000.0 0.53 972679.0 374000.0 0.52 0.7414 1.0 1944028 Maybridge1_006419 Sc1nnc(c2ccccc2)n1Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L18 compound treatment 879327.0 344000.0 0.49 944692.0 346000.0 0.48 0.6867 1.0 2072783 Maybridge1_006420 Cc1nc(cn1CC/C(=N/O)/N)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L19 compound treatment 880154.0 345000.0 0.49 986270.0 387000.0 0.54 0.7286 0.9988 2072784 Maybridge1_006421 CCC(=O)c1cc(OC)c(OC)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L20 compound treatment 877554.0 342000.0 0.49 935676.0 337000.0 0.47 0.6761 0.9998 1447787 Maybridge1_006422 CCOc1ccc(NC(=S)N2CCC(CC2)c3ccccc3OC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L21 compound treatment 912691.0 377000.0 0.54 1056094.0 457000.0 0.64 0.8301 0.9963 1007880 Maybridge1_006423 COc1ccc(NC(=O)C)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L22 compound treatment 848103.0 313000.0 0.44 959667.0 361000.0 0.5 0.6701 0.9981 2072785 Maybridge1_006424 COS(=O)(=O)c1ccc2C(=O)CC(C)(C)Oc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L23 mock treatment 836812.0 301000.0 0.43 1011342.0 412000.0 0.57 0.7097 0.9896 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 L24 mock treatment 152823.0 -383000.0 -0.54 145552.0 -454000.0 -0.63 -0.8319 -0.9972 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M01 compound treatment 824234.0 289000.0 0.41 824854.0 226000.0 0.31 0.5131 0.9914 2072786 Maybridge1_006425 CCOC(=O)CN/C(=N\O)/c1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M02 compound treatment 835914.0 301000.0 0.43 878009.0 279000.0 0.39 0.5773 0.9989 2072787 Maybridge1_006426 FC(F)(F)c1ccc(=O)[nH]c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M03 compound treatment 896613.0 361000.0 0.51 923363.0 324000.0 0.45 0.6831 0.998 2072788 Maybridge1_006427 N/C(=N\O)/c1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M04 compound treatment 846533.0 311000.0 0.44 940166.0 341000.0 0.48 0.6493 0.9994 2072789 Maybridge1_006428 Oc1nnc(o1)C2c3ccccc3Oc4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M05 compound treatment 900955.0 366000.0 0.52 902437.0 303000.0 0.42 0.6668 0.9948 2072790 Maybridge1_006429 CSc1nc(N)nc(n1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M06 compound treatment 884976.0 350000.0 0.5 916475.0 317000.0 0.44 0.6646 0.9983 2072791 Maybridge1_006430 CCC(=O)Nc1cc(F)ccc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M07 compound treatment 920687.0 385000.0 0.55 931900.0 333000.0 0.46 0.7157 0.9966 2072792 Maybridge1_006431 CCSc1nc(N)nc(n1)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M08 compound treatment 848877.0 314000.0 0.45 911517.0 312000.0 0.44 0.6234 0.9999 2072793 Maybridge1_006432 COc1ccc2nnc(c3ccc(cc3)C(F)(F)F)n2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M09 compound treatment 923089.0 388000.0 0.55 847566.0 248000.0 0.35 0.6349 0.9749 1579175 Maybridge1_006433 CSc1nc(N)nc(n1)C2(CC3CC4CC(C3)C2)C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M10 compound treatment 849632.0 314000.0 0.45 914314.0 315000.0 0.44 0.6269 1.0 1940042 Maybridge1_006434 CCOC(=O)C1=C(C)Nc2ccccc2S1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M11 compound treatment 888535.0 353000.0 0.5 925354.0 326000.0 0.46 0.6769 0.9988 1295563 Maybridge1_006435 CC(C)(C)C(=O)OCc1noc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M12 compound treatment 840074.0 305000.0 0.43 883729.0 285000.0 0.4 0.5871 0.999 2072794 Maybridge1_006436 COc1ccc(OC)c([N+](=O)[O-])c1/C=C/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M13 compound treatment 907781.0 372000.0 0.53 962431.0 363000.0 0.51 0.7328 0.9998 1533787 Maybridge1_006437 O=C1CNC(=S)N1CCc2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M14 compound treatment 896937.0 362000.0 0.51 959382.0 360000.0 0.5 0.7189 0.9999 2072795 Maybridge1_006438 FC(F)(F)c1ccc2[nH]nnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M15 compound treatment 944120.0 409000.0 0.58 977771.0 379000.0 0.53 0.7845 0.9989 1266151 Maybridge1_006439 O=C1CNC(=S)N1CCOc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M16 compound treatment 887498.0 352000.0 0.5 917293.0 318000.0 0.44 0.6679 0.9982 1729344 Maybridge1_006440 COc1ccc(OC)c2[nH]ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M17 compound treatment 896130.0 361000.0 0.51 928174.0 329000.0 0.46 0.6873 0.9985 2072796 Maybridge1_006441 CSC1=N/C(=C\c2ccc(Cl)cc2)/C(=O)N1Cc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M18 compound treatment 877186.0 342000.0 0.49 922895.0 324000.0 0.45 0.6631 0.9993 2072797 Maybridge1_006442 COc1ccc(cc1)/C(=N/NC2=NCCCN2)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M19 compound treatment 873654.0 338000.0 0.48 988471.0 389000.0 0.54 0.7242 0.9982 2072798 Maybridge1_006443 CSc1nc(nc(N)c1C#N)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M20 compound treatment 853115.0 318000.0 0.45 950420.0 351000.0 0.49 0.666 0.9992 1006201 Maybridge1_006444 CC(=O)OC(OC(=O)C)c1ccc(o1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M21 compound treatment 887400.0 352000.0 0.5 959162.0 360000.0 0.5 0.7091 1.0 2072799 Maybridge1_006445 FC(F)(F)c1ccccc1NC(=O)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M22 compound treatment 880434.0 345000.0 0.49 970187.0 371000.0 0.52 0.713 0.9996 1540353 Maybridge1_006446 CCCCn1c(=O)c2c(O)cc(=O)oc2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M23 mock treatment 848952.0 314000.0 0.45 988987.0 390000.0 0.54 0.6999 0.9952 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 M24 mock treatment 641053.0 106000.0 0.15 738321.0 139000.0 0.19 0.2436 0.992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N01 compound treatment 848267.0 313000.0 0.45 848006.0 249000.0 0.35 0.5601 0.9924 2072800 Maybridge1_006447 COc1cc(Cl)cc(CNC(C)C(=O)O)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N02 compound treatment 802345.0 267000.0 0.38 840089.0 241000.0 0.34 0.5062 0.9981 1618130 Maybridge1_006448 CCc1c(C(=O)OC)c2cc(O)ccc2n1Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N03 compound treatment 875151.0 340000.0 0.48 928361.0 329000.0 0.46 0.6664 0.9997 2072801 Maybridge1_006449 CC(=CC(NCc1ccccc1O)C(=O)O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N04 compound treatment 864952.0 330000.0 0.47 961704.0 363000.0 0.51 0.689 0.9993 2072802 Maybridge1_006450 Cc1cc(ccc1n2cccc2)c3nnc(o3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N05 compound treatment 897012.0 362000.0 0.51 975510.0 376000.0 0.52 0.7349 0.9999 1291953 Maybridge1_006451 Cc1cc2CCCn3c(=O)cc(O)c(c1)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N06 compound treatment 891381.0 356000.0 0.51 924114.0 325000.0 0.45 0.6786 0.9985 1162160 Maybridge1_006452 Cc1cc(O)c2c3[nH]ncc3ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N07 compound treatment 900032.0 365000.0 0.52 978722.0 380000.0 0.53 0.7411 0.9999 1006493 Maybridge1_006453 CCCCC(C(=O)O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N08 compound treatment 900022.0 365000.0 0.52 960259.0 361000.0 0.5 0.7229 0.9999 2072803 Maybridge1_006454 CC(=O)N[C@@H]1[C@@H](O)[C@@H]2OC(OC[C@H]2O[C@@H]1OCc3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N09 compound treatment 879856.0 345000.0 0.49 976703.0 378000.0 0.53 0.7188 0.9993 2072804 Maybridge1_006455 CC1=N/C(=C\c2ccccc2)/C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N10 compound treatment 889116.0 354000.0 0.5 956757.0 358000.0 0.5 0.7085 1.0 1355251 Maybridge1_006456 OC(=O)C(CC(=O)c1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N11 compound treatment 912922.0 378000.0 0.54 1019251.0 420000.0 0.59 0.794 0.999 1027704 Maybridge1_006457 OC(=O)c1ccccc1Oc2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N12 compound treatment 881229.0 346000.0 0.49 946590.0 347000.0 0.48 0.6905 1.0 2072805 Maybridge1_006458 FC(F)(F)c1ccc2[nH]c(S)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N13 compound treatment 865371.0 330000.0 0.47 973504.0 374000.0 0.52 0.7011 0.9986 2072806 Maybridge1_006459 Cc1cc(ccc1[N+](=O)[O-])C(=O)NNC(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N14 compound treatment 848161.0 313000.0 0.44 937101.0 338000.0 0.47 0.6479 0.9996 1003119 Maybridge1_006460 O=C(CC(=O)Nc1ccccc1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N15 compound treatment 899276.0 364000.0 0.52 1031853.0 433000.0 0.6 0.7927 0.9971 1913136 Maybridge1_006461 OC(=O)c1ccccc1N/C=C/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N16 compound treatment 887922.0 353000.0 0.5 949103.0 350000.0 0.49 0.6997 0.9999 2072807 Maybridge1_006462 CCOC(=O)C1CCN(CC1)C(=S)Nc2ccccc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N17 compound treatment 934156.0 399000.0 0.57 952116.0 353000.0 0.49 0.7492 0.9975 1208730 Maybridge1_006463 CCc1cc2c(cc1C(=O)CSc3ncccc3C(=O)O)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N18 compound treatment 844830.0 310000.0 0.44 912034.0 313000.0 0.44 0.6198 1.0 2072808 Maybridge1_006464 Cc1c(OCc2cccc(OC(F)(F)F)c2)ccc3C(=O)CC(C)(C)Oc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N19 compound treatment 885610.0 350000.0 0.5 991373.0 392000.0 0.55 0.7391 0.9989 1013422 Maybridge1_006465 CC(=O)OC(C(=O)O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N20 compound treatment 856885.0 322000.0 0.46 894768.0 296000.0 0.41 0.6149 0.9987 2072809 Maybridge1_006466 COc1ccccc1C2CCN(CC2)c3ncccc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N21 compound treatment 891678.0 356000.0 0.51 1017436.0 418000.0 0.58 0.7709 0.9975 2072810 Maybridge1_006467 ClC1=C(Cl)C(=O)OC1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N22 compound treatment 876088.0 341000.0 0.48 951029.0 352000.0 0.49 0.6897 1.0 1057919 Maybridge1_006468 OC(=O)c1ccccc1C(=O)Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N23 mock treatment 859868.0 325000.0 0.46 1006911.0 408000.0 0.57 0.7285 0.9946 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 N24 mock treatment 318492.0 -217000.0 -0.31 599315.0 199.0 0.0 -0.2178 -0.7065 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O01 compound treatment 785703.0 250000.0 0.36 800025.0 201000.0 0.28 0.4499 0.993 1440413 Maybridge1_006469 COC(=O)c1c(NC(=O)NN2CCCCC2)onc1c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O02 compound treatment 826740.0 291000.0 0.41 822513.0 223000.0 0.31 0.5134 0.9901 2072811 Maybridge1_006470 Brc1c[nH]nc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O03 compound treatment 865681.0 330000.0 0.47 882285.0 283000.0 0.39 0.6115 0.9963 2072812 Maybridge1_006471 CN(C)C(=O)O/N=C(\N)/c1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O04 compound treatment 831509.0 296000.0 0.42 882687.0 284000.0 0.4 0.5775 0.9995 1434269 Maybridge1_006472 NNC(=O)C1c2ccccc2Oc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O05 compound treatment 861895.0 327000.0 0.46 870559.0 271000.0 0.38 0.5961 0.9949 1739883 Maybridge1_006473 COc1nc(N)nc(n1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O06 compound treatment 824489.0 289000.0 0.41 873118.0 274000.0 0.38 0.561 0.9993 2072813 Maybridge1_006474 CCC(=O)Nc1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O07 compound treatment 874644.0 339000.0 0.48 914470.0 315000.0 0.44 0.6522 0.9989 2072814 Maybridge1_006475 CSc1nc(N)nc(n1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O08 compound treatment 841780.0 306000.0 0.44 895632.0 297000.0 0.41 0.6006 0.9997 1571659 Maybridge1_006476 Oc1ncnc2n(ncc12)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O09 compound treatment 863915.0 329000.0 0.47 929488.0 330000.0 0.46 0.6562 1.0 1382127 Maybridge1_006477 Nc1nc(O)nc(n1)C2(CC3CC4CC(C3)C2)C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O10 compound treatment 836595.0 301000.0 0.43 879824.0 281000.0 0.39 0.5798 0.999 1374339 Maybridge1_006478 Cc1cc2CCCn3c(=O)c(c(O)c(c1)c23)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O11 compound treatment 884506.0 349000.0 0.5 902606.0 303000.0 0.42 0.6504 0.9968 2072815 Maybridge1_006479 O=C1CNC(=S)N1Cc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O12 compound treatment 825530.0 290000.0 0.41 877027.0 278000.0 0.39 0.5659 0.9995 1003148 Maybridge1_006480 CC(=O)Nc1ccc(I)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O13 compound treatment 861395.0 326000.0 0.46 934942.0 336000.0 0.47 0.6591 1.0 1400940 Maybridge1_006481 O=C1CNC(=S)N1CCc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O14 compound treatment 853786.0 318000.0 0.45 893526.0 294000.0 0.41 0.6106 0.9988 2072816 Maybridge1_006482 O=c1[nH]c(=S)[nH]c(C2CCCCC2)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O15 compound treatment 877960.0 343000.0 0.49 954450.0 355000.0 0.5 0.695 1.0 2072817 Maybridge1_006483 COc1nc(N)nc(SC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O16 compound treatment 826003.0 291000.0 0.41 899494.0 300000.0 0.42 0.5885 1.0 2072818 Maybridge1_006484 O=C(CC#N)NNC(=S)NC1CCCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O17 compound treatment 881615.0 346000.0 0.49 927559.0 328000.0 0.46 0.6721 0.9993 2072819 Maybridge1_006485 Fc1ccc(SC(=O)Nc2ccc(Cl)cc2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O18 compound treatment 851850.0 317000.0 0.45 920494.0 321000.0 0.45 0.6352 1.0 1339858 Maybridge1_006486 Oc1nc(Nc2ccccc2)nc(Nc3ccccc3)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O19 compound treatment 836864.0 302000.0 0.43 945163.0 346000.0 0.48 0.6445 0.9983 2072820 Maybridge1_006487 N/C(=N\O)/c1cnccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O20 compound treatment 811898.0 277000.0 0.39 937401.0 338000.0 0.47 0.6117 0.9959 2072821 Maybridge1_006488 CS(=O)(=O)c1ccc(cc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O21 compound treatment 868790.0 333000.0 0.47 965318.0 366000.0 0.51 0.6965 0.9993 2072822 Maybridge1_006489 FC(F)(F)c1cnc(c(Cl)c1)n2nc(oc2=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O22 compound treatment 804115.0 269000.0 0.38 917232.0 318000.0 0.44 0.584 0.9972 1687593 Maybridge1_006490 CCCCc1ccc(NC(=O)CSc2nnc(N)s2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O23 mock treatment 865448.0 330000.0 0.47 946887.0 348000.0 0.49 0.6749 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 O24 mock treatment 297590.0 -238000.0 -0.34 315569.0 -284000.0 -0.4 -0.5187 -0.997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P01 compound treatment 781323.0 246000.0 0.35 806082.0 207000.0 0.29 0.4515 0.9954 2072823 Maybridge1_006491 CC(NCc1cc2ccccc2cc1O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P02 compound treatment 822198.0 287000.0 0.41 832247.0 233000.0 0.33 0.5184 0.9937 2072824 Maybridge1_006492 Cc1ccc2cc(F)ccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P03 compound treatment 824388.0 289000.0 0.41 844224.0 245000.0 0.34 0.5324 0.9958 1443250 Maybridge1_006493 Oc1cc(=O)[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P04 compound treatment 842419.0 307000.0 0.44 841340.0 242000.0 0.34 0.5477 0.9919 2072825 Maybridge1_006494 OC(=O)CNC(=O)CCCCC(=O)NCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P05 compound treatment 843494.0 308000.0 0.44 873093.0 274000.0 0.38 0.5801 0.9977 2072826 Maybridge1_006495 OC(=O)[C@@H]1CSC(N1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P06 compound treatment 835422.0 300000.0 0.43 864162.0 265000.0 0.37 0.5632 0.9974 2072827 Maybridge1_006496 CCCCCCCCCC(=O)Nc1nc-2c(Cc3ccccc23)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P07 compound treatment 841531.0 306000.0 0.44 872322.0 273000.0 0.38 0.5773 0.9978 1071563 Maybridge1_006497 Clc1ccc(OC(=O)CC(=O)Oc2ccc(Cl)cc2Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P08 compound treatment 838434.0 303000.0 0.43 863530.0 264000.0 0.37 0.5656 0.997 2072828 Maybridge1_006498 COc1cccc(c1)C2CCCCN(C)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P09 compound treatment 848810.0 313000.0 0.45 888798.0 290000.0 0.4 0.6009 0.9988 2072829 Maybridge1_006499 Ic1ccc2[nH]ccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P10 compound treatment 827915.0 293000.0 0.42 849744.0 251000.0 0.35 0.5414 0.9962 2072830 Maybridge1_006500 COc1ccc2nccc(C(=O)C3CC4CCN3CC4C=C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P11 compound treatment 830286.0 295000.0 0.42 870583.0 271000.0 0.38 0.5643 0.9987 2072831 Maybridge1_006501 CC(=O)c1c(O)c2ccccc2n(C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P12 compound treatment 833720.0 298000.0 0.42 880891.0 282000.0 0.39 0.5779 0.9993 2072832 Maybridge1_006502 CCC(=O)N/N=C(\C)/c1ccc(Oc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P13 compound treatment 819860.0 285000.0 0.4 864271.0 265000.0 0.37 0.5476 0.999 2072833 Maybridge1_006503 [O-][N+](=O)c1cc(ccc1N2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P14 compound treatment 814699.0 279000.0 0.4 868531.0 269000.0 0.38 0.5466 0.9996 1387909 Maybridge1_006504 Cc1ccc(C)c(COc2ccc(C)nc2N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P15 compound treatment 836291.0 301000.0 0.43 908388.0 309000.0 0.43 0.6076 1.0 1089969 Maybridge1_006505 Oc1c(cnc2ccccc12)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P16 compound treatment 835068.0 300000.0 0.43 895473.0 296000.0 0.41 0.5937 0.9999 2072834 Maybridge1_006506 CCOC(=O)C1CCN(CC1)C(=S)Nc2ccccc2OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P17 compound treatment 812930.0 278000.0 0.39 906554.0 307000.0 0.43 0.5823 0.9991 2072835 Maybridge1_006507 OC(=O)c1cccnc1SCC(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P18 compound treatment 829744.0 294000.0 0.42 890124.0 291000.0 0.41 0.5831 0.9999 2072836 Maybridge1_006508 Cn1c(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P19 compound treatment 829331.0 294000.0 0.42 897021.0 298000.0 0.42 0.5894 1.0 2072837 Maybridge1_006509 CC(=O)OCCCCN1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P20 compound treatment 814871.0 280000.0 0.4 900719.0 302000.0 0.42 0.5785 0.9996 2072838 Maybridge1_006510 COc1ccccc1C2CCN(CC2)c3ccc(cc3[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P21 compound treatment 806264.0 271000.0 0.39 911131.0 312000.0 0.44 0.5802 0.9982 2072839 Maybridge1_006511 CCOC(=O)CNc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P22 compound treatment 810575.0 275000.0 0.39 898097.0 299000.0 0.42 0.5716 0.9995 2072840 Maybridge1_006512 CC1CC2CN(C)C1C/C(=N/O)/C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P23 mock treatment 769677.0 234000.0 0.33 871171.0 272000.0 0.38 0.504 0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.559 P24 mock treatment 263999.0 -271000.0 -0.39 342884.0 -256000.0 -0.36 -0.5255 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A01 compound treatment 814892.0 241000.0 0.34 835133.0 245000.0 0.34 0.4833 1.0 2072841 Maybridge1_006513 CN1CC2CCC1C/C(=N/O)/C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A02 compound treatment 810134.0 236000.0 0.34 826909.0 236000.0 0.33 0.4704 1.0 2072842 Maybridge1_006514 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A03 compound treatment 826930.0 253000.0 0.36 828590.0 238000.0 0.33 0.4889 0.9992 1577271 Maybridge1_006515 Fc1cccc(OCC(=O)Nc2ccccc2C(=O)c3ccccc3Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A04 compound treatment 842405.0 268000.0 0.38 830343.0 240000.0 0.33 0.5062 0.9979 2072843 Maybridge1_006516 Cc1cccc(c1)n2c(S)nnc2CSCc3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A05 compound treatment 896231.0 322000.0 0.46 858263.0 268000.0 0.37 0.5879 0.9949 1557801 Maybridge1_006517 COc1ccc(CC2CCC(=NO)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A06 compound treatment 894653.0 320000.0 0.46 882591.0 292000.0 0.41 0.6103 0.9984 2072844 Maybridge1_006518 CN(C(=O)CSc1nnc(COc2ccc(C)c3CCCc32)n1c4ccccc4)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A07 compound treatment 890001.0 316000.0 0.45 902328.0 312000.0 0.43 0.625 0.9999 1285371 Maybridge1_006519 COc1ccc(cc1)C(=O)N2CCC(CC2)c3ccccc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A08 compound treatment 905661.0 331000.0 0.47 915354.0 325000.0 0.45 0.6536 0.9998 1737597 Maybridge1_006520 OC(=O)CCC1CCCC(CCC(=O)O)C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A09 compound treatment 909175.0 335000.0 0.48 911579.0 321000.0 0.45 0.6534 0.9995 1393835 Maybridge1_006521 CC(=O)N(O)CC(=O)Nc1ccccc1C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A10 compound treatment 887678.0 313000.0 0.45 882195.0 292000.0 0.41 0.6029 0.999 1166338 Maybridge1_006522 Cc1onc(c1C(=O)NCC(=O)O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A11 compound treatment 901139.0 327000.0 0.46 935142.0 345000.0 0.48 0.6686 0.9999 1059002 Maybridge1_006523 OC(=O)CSCc1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A12 compound treatment 910048.0 336000.0 0.48 925753.0 335000.0 0.47 0.6683 0.9999 2072845 Maybridge1_006524 Cc1ccc(OCc2nnc(SCC(=O)c3ccc(F)c(F)c3)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A13 compound treatment 913276.0 339000.0 0.48 920371.0 330000.0 0.46 0.6662 0.9997 1464667 Maybridge1_006525 COc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccccc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A14 compound treatment 926748.0 353000.0 0.5 942213.0 352000.0 0.49 0.7013 0.9999 1370472 Maybridge1_006526 COc1ccc(cc1)C(=O)c2cc3cc(Br)cc(Br)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A15 compound treatment 917459.0 343000.0 0.49 904219.0 314000.0 0.44 0.6545 0.9985 1250811 Maybridge1_006527 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A16 compound treatment 923637.0 349000.0 0.5 959190.0 369000.0 0.51 0.7149 0.9999 1338954 Maybridge1_006528 COc1ccc(cc1)C(=O)c2cc3cc(Cl)cc(Cl)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A17 compound treatment 929426.0 355000.0 0.51 938567.0 348000.0 0.49 0.7004 0.9998 2072846 Maybridge1_006529 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A18 compound treatment 908499.0 334000.0 0.48 932683.0 342000.0 0.48 0.6736 1.0 2072847 Maybridge1_006530 Cc1cc(Br)c(OCc2nnc(S)n2CC=C)c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A19 compound treatment 895515.0 321000.0 0.46 924805.0 334000.0 0.47 0.6528 0.9999 2072848 Maybridge1_006531 OC(=O)CCCNCc1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A20 compound treatment 883204.0 309000.0 0.44 919013.0 328000.0 0.46 0.6347 0.9998 2072849 Maybridge1_006532 Cc1onc(c1C(=O)Nc2cc(ccc2Oc3ccc(C)c4CCCc43)C(F)(F)F)c5c(F)cccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A21 compound treatment 878945.0 305000.0 0.43 895324.0 305000.0 0.43 0.607 1.0 2072850 Maybridge1_006533 Clc1ccccc1NC(=S)NNC(=O)CSCc2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A22 compound treatment 839526.0 265000.0 0.38 866442.0 276000.0 0.38 0.5389 1.0 2072851 Maybridge1_006534 Cc1ccc(Oc2ccc(cc2NS(=O)(=O)c3cc(ccc3C)[N+](=O)[O-])C(F)(F)F)c4CCCc41 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A23 mock treatment 802471.0 228000.0 0.32 843464.0 253000.0 0.35 0.479 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 A24 mock treatment 138270.0 -436000.0 -0.62 155411.0 -435000.0 -0.61 -0.8675 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B01 compound treatment 835242.0 261000.0 0.37 814273.0 224000.0 0.31 0.4831 0.9963 1671490 Maybridge1_006535 Cc1cccc(C)c1NC(=O)c2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B02 compound treatment 835133.0 261000.0 0.37 862682.0 272000.0 0.38 0.5308 0.9999 2072852 Maybridge1_006536 CCOC(=O)/C(=C/Nc1ccccc1Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B03 compound treatment 930285.0 356000.0 0.51 916510.0 326000.0 0.45 0.6795 0.9986 2072853 Maybridge1_006537 CC(=O)c1ccc(Nc2cc(C)nc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B04 compound treatment 910934.0 337000.0 0.48 913587.0 323000.0 0.45 0.6572 0.9995 2072854 Maybridge1_006538 Cc1c(sc2ccccc12)C(=O)COc3nc(cc(c3C#N)C(F)(F)F)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B05 compound treatment 932260.0 358000.0 0.51 908055.0 318000.0 0.44 0.6732 0.9976 2072855 Maybridge1_006539 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2cccs2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B06 compound treatment 952952.0 379000.0 0.54 924229.0 334000.0 0.47 0.7099 0.9974 1292709 Maybridge1_006540 Cc1ccc2cc(NC(=O)c3ccccc3C)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B07 compound treatment 954808.0 381000.0 0.54 951526.0 361000.0 0.5 0.7387 0.9993 2072856 Maybridge1_006541 CC(=O)C(=NNc1cccc(c1)C(F)(F)F)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B08 compound treatment 870662.0 296000.0 0.42 929210.0 339000.0 0.47 0.6321 0.9984 2072857 Maybridge1_006542 NC/1=NNC(=O)\C1=C/c2cc(ccc2N3CCOCC3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B09 compound treatment 1001555.0 427000.0 0.61 923037.0 333000.0 0.46 0.7576 0.9911 1521748 Maybridge1_006543 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3ccccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B10 compound treatment 952399.0 378000.0 0.54 975066.0 385000.0 0.54 0.7595 1.0 1438392 Maybridge1_006544 CC1(C)CC(=O)c2ccc(OCC(=O)O)cc2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B11 compound treatment 979914.0 406000.0 0.58 1001929.0 411000.0 0.57 0.8137 1.0 2072858 Maybridge1_006545 COc1ccc(Oc2ncccc2NC(=O)Nc3cccc(c3)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B12 compound treatment 947139.0 373000.0 0.53 1000516.0 410000.0 0.57 0.7793 0.9993 1565207 Maybridge1_006546 Nc1nc2ccc(F)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B13 compound treatment 999304.0 425000.0 0.6 986230.0 396000.0 0.55 0.8177 0.999 2072859 Maybridge1_006547 COc1ccc(Oc2ncccc2NC(=O)c3cccc4ccccc34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B14 compound treatment 953226.0 379000.0 0.54 976209.0 386000.0 0.54 0.7615 1.0 2072860 Maybridge1_006548 O=C(CCCCC(=O)NCC(=O)ON1C(=O)CCC1=O)NCC(=O)ON2C(=O)CCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B15 compound treatment 1003104.0 429000.0 0.61 1010875.0 420000.0 0.59 0.8458 0.9998 2072861 Maybridge1_006549 CC(C)(C)c1ccc(Oc2ncccc2NS(=O)(=O)c3ccccc3C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B16 compound treatment 915911.0 342000.0 0.49 945443.0 355000.0 0.5 0.6936 1.0 1050253 Maybridge1_006550 CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B17 compound treatment 994262.0 420000.0 0.6 1015531.0 425000.0 0.59 0.8415 1.0 1543501 Maybridge1_006551 CCOc1ccc(CC(C(=O)O)C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B18 compound treatment 800768.0 227000.0 0.32 856687.0 266000.0 0.37 0.4903 0.9975 2072862 Maybridge1_006552 Clc1c2C(=O)CC(=O)c2c(Cl)c(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B19 compound treatment 970931.0 397000.0 0.56 998849.0 408000.0 0.57 0.8016 1.0 2072863 Maybridge1_006553 CC(=O)c1sc(nc1C)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B20 compound treatment 888167.0 314000.0 0.45 945219.0 355000.0 0.49 0.6655 0.9987 2072864 Maybridge1_006554 COc1ccc(C=C2CCC(=O)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B21 compound treatment 908379.0 334000.0 0.48 934778.0 344000.0 0.48 0.6755 1.0 1015396 Maybridge1_006555 O=C(CC(=O)c1cccnc1)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B22 compound treatment 880908.0 307000.0 0.44 929317.0 339000.0 0.47 0.6425 0.9992 2072865 Maybridge1_006556 Cc1cc2/C(=N\O)/CCCc2nn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B23 mock treatment 874969.0 301000.0 0.43 903779.0 313000.0 0.44 0.6114 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 B24 mock treatment 146338.0 -428000.0 -0.61 156103.0 -434000.0 -0.61 -0.8587 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C01 compound treatment 759136.0 185000.0 0.26 776179.0 186000.0 0.26 0.369 1.0 1704397 Maybridge1_006557 COc1ccc(CCNC(=O)C2CCCO2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C02 compound treatment 776285.0 202000.0 0.29 835669.0 245000.0 0.34 0.445 0.9963 1520985 Maybridge1_006558 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C03 compound treatment 814357.0 240000.0 0.34 895889.0 305000.0 0.43 0.5426 0.994 2072866 Maybridge1_006559 Cn1cnnc1SCc2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C04 compound treatment 813795.0 240000.0 0.34 879239.0 289000.0 0.4 0.5256 0.9965 2072867 Maybridge1_006560 CCOC(=O)/C(=N/Nc1ccc(C)cc1)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C05 compound treatment 881149.0 307000.0 0.44 902134.0 312000.0 0.43 0.616 1.0 2072868 Maybridge1_006561 Cn1c2CCC/C(=N\O)/c2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C06 compound treatment 816628.0 242000.0 0.34 843847.0 253000.0 0.35 0.4936 0.9999 1083147 Maybridge1_006562 Cc1cccc(c1)C(=O)NCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C07 compound treatment 811686.0 237000.0 0.34 891110.0 301000.0 0.42 0.5352 0.9942 2072869 Maybridge1_006563 CC1(C)C(N)C2(C)CCC1C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C08 compound treatment 856019.0 282000.0 0.4 893245.0 303000.0 0.42 0.5819 0.9997 2072870 Maybridge1_006564 COc1ccc(OC)c(Sc2cc(c(Cl)cc2[N+](=O)[O-])n3cccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C09 compound treatment 888290.0 314000.0 0.45 890297.0 300000.0 0.42 0.6115 0.9995 1028362 Maybridge1_006565 NC(=O)NC(=O)c1cccnc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C10 compound treatment 872281.0 298000.0 0.42 851602.0 261000.0 0.36 0.5572 0.9971 2072871 Maybridge1_006566 FC(F)(F)c1ccc(cc1)C(=O)CSc2nnc(CSCc3cccc4ccccc34)n2c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C11 compound treatment 892388.0 318000.0 0.45 882881.0 292000.0 0.41 0.6083 0.9987 2072872 Maybridge1_006567 [O-][N+](=O)c1cccc(c1)C(=O)Nc2nnc(SCC(=O)Nc3ccc4OCOc4c3)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C12 compound treatment 864968.0 291000.0 0.41 849340.0 259000.0 0.36 0.5476 0.9977 2072873 Maybridge1_006568 [O-][N+](=O)c1ccc2oc(cc2c1)C(=O)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C13 compound treatment 874232.0 300000.0 0.43 905221.0 315000.0 0.44 0.612 0.9999 2072874 Maybridge1_006569 Cc1nc(cn1Cc2ccc(F)cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C14 compound treatment 846029.0 272000.0 0.39 873544.0 283000.0 0.39 0.5524 0.9999 2072875 Maybridge1_006570 Clc1ccc(NC(=O)CN2CCCCC2)c(c1)C(=O)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C15 compound treatment 856057.0 282000.0 0.4 954393.0 364000.0 0.51 0.6423 0.9932 2072876 Maybridge1_006571 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C16 compound treatment 867439.0 293000.0 0.42 902647.0 312000.0 0.44 0.6027 0.9998 2072877 Maybridge1_006572 FC(F)(F)Oc1ccc(cc1)C(=O)c2cc3cc(Cl)cc(Cl)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C17 compound treatment 875517.0 301000.0 0.43 897096.0 307000.0 0.43 0.6053 1.0 1447824 Maybridge1_006573 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(F)cc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C18 compound treatment 833268.0 259000.0 0.37 887221.0 297000.0 0.41 0.5531 0.9983 1633199 Maybridge1_006574 Clc1cc(Cl)c2oc(cc2c1)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C19 compound treatment 855806.0 282000.0 0.4 913873.0 323000.0 0.45 0.602 0.9982 1019887 Maybridge1_006575 OC1(C(=O)Nc2ccccc21)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C20 compound treatment 803219.0 229000.0 0.33 883584.0 293000.0 0.41 0.5193 0.9937 2072878 Maybridge1_006576 OS(=O)(=O)c1ccc(Nc2ncnc3cc(Cl)ccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C21 compound treatment 856999.0 283000.0 0.4 900324.0 310000.0 0.43 0.5899 0.9994 2072879 Maybridge1_006577 Cc1cccc(NC(=S)NNC(=O)CSCc2cccc3ccccc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C22 compound treatment 827320.0 253000.0 0.36 899553.0 309000.0 0.43 0.5593 0.996 1193041 Maybridge1_006578 Cc1ccc(C)n1c2ccc(cc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C23 mock treatment 820368.0 246000.0 0.35 858782.0 268000.0 0.37 0.5121 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 C24 mock treatment 144012.0 -430000.0 -0.61 150183.0 -440000.0 -0.61 -0.8669 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D01 compound treatment 860106.0 286000.0 0.41 836915.0 246000.0 0.34 0.5305 0.9965 1425989 Maybridge1_006579 C1COC2(O1)C3NCC4(CCCCC4)CN3c5ccccc52 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D02 compound treatment 831051.0 257000.0 0.37 825622.0 235000.0 0.33 0.4901 0.9986 2072880 Maybridge1_006580 CN(C(=O)CSc1nccc(n1)c2sc(nc2C)c3ccc(Cl)cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D03 compound treatment 913665.0 339000.0 0.48 955224.0 365000.0 0.51 0.701 0.9997 2072881 Maybridge1_006581 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2ccccc2F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D04 compound treatment 986965.0 413000.0 0.59 1044985.0 454000.0 0.63 0.8632 0.9993 2072882 Maybridge1_006582 COC(=O)/C(=C/c1cc(Br)c(OC(=O)C)c(OC)c1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D05 compound treatment 896954.0 323000.0 0.46 976110.0 386000.0 0.54 0.7048 0.9969 2072883 Maybridge1_006583 [O-][N+](=O)c1cc(ccc1NCCNC(=S)Nc2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D06 compound treatment 919643.0 345000.0 0.49 943575.0 353000.0 0.49 0.6955 1.0 1340853 Maybridge1_006584 Cc1ccc2cc(NC(=O)c3ccc(cc3)C(C)(C)C)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D07 compound treatment 998705.0 424000.0 0.6 967872.0 377000.0 0.53 0.799 0.9977 2072884 Maybridge1_006585 Cc1ccc(C)n1c2ccc(cc2)C(=O)NNS(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D08 compound treatment 939005.0 365000.0 0.52 965752.0 375000.0 0.52 0.7369 1.0 2072885 Maybridge1_006586 COC(=O)/C(=C/c1ccc(OC)c(OC)c1Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D09 compound treatment 991038.0 417000.0 0.59 953818.0 363000.0 0.51 0.7774 0.997 1483254 Maybridge1_006587 CCCc1ccc(cc1)C(=O)Nc2cccnc2Oc3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D10 compound treatment 957774.0 384000.0 0.55 991109.0 401000.0 0.56 0.7808 0.9999 1594559 Maybridge1_006588 CCOC(=O)COc1ccc2C(=O)CC(C)(C)Oc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D11 compound treatment 984080.0 410000.0 0.58 991568.0 401000.0 0.56 0.8077 0.9998 2072886 Maybridge1_006589 COc1ccc(Oc2ncccc2NC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D12 compound treatment 951328.0 377000.0 0.54 966575.0 376000.0 0.52 0.7501 0.9999 2072887 Maybridge1_006590 C1C2C3C4C5C3C6OC5(C(C14)C26)c7ccccc7 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D13 compound treatment 967688.0 393000.0 0.56 1041379.0 451000.0 0.63 0.8403 0.9983 2072888 Maybridge1_006591 CCCCCCCCCC(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D14 compound treatment 694875.0 121000.0 0.17 722645.0 132000.0 0.18 0.2516 0.9994 2072889 Maybridge1_006592 [O-][N+](=O)c1cccc2C(=O)CC(=O)c21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D15 compound treatment 983587.0 409000.0 0.58 1002064.0 412000.0 0.57 0.8175 1.0 2072890 Maybridge1_006593 [O-][N+](=O)c1cc(Cl)c(cc1Sc2ccc(F)cc2Cl)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D16 compound treatment 997755.0 424000.0 0.6 1012252.0 422000.0 0.59 0.8418 0.9999 2072891 Maybridge1_006594 CC(=O)N[C@@H](Cc1ccc(OC(=O)C)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D17 compound treatment 957773.0 384000.0 0.55 1069855.0 479000.0 0.67 0.8584 0.9949 1129476 Maybridge1_006595 Clc1ccc(Sc2ncccc2NC(=O)C(C3CCCC3)c4ccccc4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D18 compound treatment 945026.0 371000.0 0.53 968523.0 378000.0 0.53 0.7457 1.0 1547187 Maybridge1_006596 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D19 compound treatment 977583.0 403000.0 0.57 1001740.0 411000.0 0.57 0.8112 1.0 2072892 Maybridge1_006597 FC(F)(F)c1cc([nH]c(=O)c1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D20 compound treatment 882203.0 308000.0 0.44 992739.0 402000.0 0.56 0.7064 0.9925 1554163 Maybridge1_006598 OC(C(=O)Nc1ccc(Cl)cc1)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D21 compound treatment 979417.0 405000.0 0.58 1033687.0 443000.0 0.62 0.8445 0.9994 2072893 Maybridge1_006599 COc1ccc(cc1)C(=O)CN2CCN(CC2)c3cc(C)nc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D22 compound treatment 879319.0 305000.0 0.43 928370.0 338000.0 0.47 0.64 0.9992 2072894 Maybridge1_006600 CC(C)(NO)/C(=N\O)/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D23 mock treatment 944895.0 371000.0 0.53 950653.0 360000.0 0.5 0.7279 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 D24 mock treatment 147092.0 -427000.0 -0.61 151388.0 -439000.0 -0.61 -0.8626 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E01 compound treatment 836161.0 262000.0 0.37 835885.0 245000.0 0.34 0.5054 0.9991 1627375 Maybridge1_006601 CN1C(=O)CN=C(c2ccccc2)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E02 compound treatment 855814.0 282000.0 0.4 873632.0 283000.0 0.39 0.5624 1.0 2072895 Maybridge1_006602 Sc1nnc(CSCc2cccc3ccccc23)n1c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E03 compound treatment 887900.0 314000.0 0.45 895257.0 305000.0 0.43 0.616 0.9997 2072896 Maybridge1_006603 COc1ccccc1C2CCN(CC2)c3ccc(CO)cc3[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E04 compound treatment 908097.0 334000.0 0.47 957137.0 367000.0 0.51 0.6973 0.9993 2072897 Maybridge1_006604 Nc1nnc(Sc2cc(c(Cl)cc2[N+](=O)[O-])n3cccc3)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E05 compound treatment 925949.0 352000.0 0.5 988169.0 398000.0 0.55 0.7459 0.9987 1141662 Maybridge1_006605 COc1ccccc1C2CCN(CC2)C(=O)c3c(C)onc3c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E06 compound treatment 931693.0 357000.0 0.51 993025.0 403000.0 0.56 0.7564 0.9988 2072898 Maybridge1_006606 Cc1ccc(OCc2nnc(SCC(=O)Nc3ccc(cc3)C4CCCCC4)n2c5ccccc5)c6CCCc61 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E07 compound treatment 942967.0 369000.0 0.52 1016333.0 426000.0 0.59 0.7907 0.9981 1914101 Maybridge1_006607 OC(=O)c1ccccc1C(=O)Nc2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E08 compound treatment 906741.0 333000.0 0.47 978742.0 388000.0 0.54 0.7172 0.9977 2072899 Maybridge1_006608 CCOC(=O)CCSc1cc(c(Cl)cc1[N+](=O)[O-])n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E09 compound treatment 935504.0 361000.0 0.51 990722.0 400000.0 0.56 0.758 0.9991 1225998 Maybridge1_006609 Clc1ccc(OC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E10 compound treatment 917790.0 344000.0 0.49 1010379.0 420000.0 0.59 0.7595 0.9959 2072900 Maybridge1_006610 [O-][N+](=O)c1ccc2oc(cc2c1)C(=O)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E11 compound treatment 950279.0 376000.0 0.53 1033620.0 443000.0 0.62 0.8151 0.9974 1666166 Maybridge1_006611 O=C1N(CCC#N)C2CCCCC2C31OCCO3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E12 compound treatment 901308.0 327000.0 0.47 960526.0 370000.0 0.52 0.6938 0.9987 2072901 Maybridge1_006612 [O-][N+](=O)c1cc(Cl)c(cc1N2CCOCC2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E13 compound treatment 917537.0 343000.0 0.49 1030807.0 440000.0 0.61 0.7794 0.9935 1653130 Maybridge1_006613 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3cc(C)no3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E14 compound treatment 924495.0 350000.0 0.5 1000080.0 410000.0 0.57 0.7561 0.9977 2072902 Maybridge1_006614 Clc1ccc(NC(=O)CN2CCOCC2)c(c1)C(=O)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E15 compound treatment 977632.0 403000.0 0.57 1035083.0 445000.0 0.62 0.8441 0.9992 1328099 Maybridge1_006615 CCCCc1ccc(cc1)S(=O)(=O)N2CCC(CC2)c3ccccc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E16 compound treatment 942792.0 369000.0 0.52 1028446.0 438000.0 0.61 0.8025 0.9971 2072903 Maybridge1_006616 COc1cc(I)c(OC)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E17 compound treatment 984289.0 410000.0 0.58 1079628.0 489000.0 0.68 0.8947 0.997 2072904 Maybridge1_006617 CCCCOc1ccc(cc1)S(=O)(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E18 compound treatment 937501.0 363000.0 0.52 1023218.0 433000.0 0.6 0.792 0.997 1550589 Maybridge1_006618 Cc1ccc(C)c2c(O)ccnc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E19 compound treatment 953338.0 379000.0 0.54 1042447.0 452000.0 0.63 0.8269 0.997 2072905 Maybridge1_006619 CC(=O)Nc1cccc(OCCCN2C(=O)c3ccccc3C2=O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E20 compound treatment 937046.0 363000.0 0.52 1052044.0 462000.0 0.64 0.82 0.994 1437311 Maybridge1_006620 C1CN(C1)C=C(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E21 compound treatment 961292.0 387000.0 0.55 936010.0 345000.0 0.48 0.73 0.9978 2072906 Maybridge1_006621 FC(F)(F)Oc1ccc(NC(=S)NNC(=O)CSCc2cccc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E22 compound treatment 859028.0 285000.0 0.41 1010230.0 420000.0 0.59 0.7003 0.9838 2072907 Maybridge1_006622 Clc1ccc2c(=O)[nH]cnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E23 mock treatment 933359.0 359000.0 0.51 990153.0 400000.0 0.56 0.7553 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 E24 mock treatment 139978.0 -434000.0 -0.62 160315.0 -430000.0 -0.6 -0.8609 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F01 compound treatment 868078.0 294000.0 0.42 835654.0 245000.0 0.34 0.5372 0.995 1196658 Maybridge1_006623 ON=C1CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F02 compound treatment 896296.0 322000.0 0.46 851970.0 261000.0 0.36 0.5817 0.9936 2072908 Maybridge1_006624 CCOC(=O)COc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F03 compound treatment 902858.0 329000.0 0.47 982777.0 392000.0 0.55 0.7173 0.9969 1065469 Maybridge1_006625 Oc1nc(nc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F04 compound treatment 932701.0 358000.0 0.51 976703.0 386000.0 0.54 0.7413 0.9996 2072909 Maybridge1_006626 CCOC(=O)/C(=C/Nc1cc(C)ccn1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F05 compound treatment 999335.0 425000.0 0.6 1007006.0 416000.0 0.58 0.8382 0.9998 2072910 Maybridge1_006627 Cc1onc(c1C(=O)NCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F06 compound treatment 917912.0 344000.0 0.49 968659.0 378000.0 0.53 0.7185 0.9993 1642696 Maybridge1_006628 COc1ccc(cc1)C(=O)c2oc3ccc4ccccc4c3c2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F07 compound treatment 997344.0 423000.0 0.6 1044861.0 454000.0 0.63 0.8736 0.9997 2072911 Maybridge1_006629 CCCc1ccc(cc1)S(=O)(=O)NNC(=O)c2ccc(cc2)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F08 compound treatment 971937.0 398000.0 0.57 1024454.0 434000.0 0.61 0.8279 0.9994 2072912 Maybridge1_006630 CC(=O)CC1(O)C(=O)Nc2ccc(F)cc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F09 compound treatment 1019811.0 446000.0 0.63 1069867.0 479000.0 0.67 0.9208 0.9996 2072913 Maybridge1_006631 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3ccccc3C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F10 compound treatment 910358.0 336000.0 0.48 976694.0 386000.0 0.54 0.7189 0.9982 1110972 Maybridge1_006632 C1=CC(=C(c2ccccc2)c3ccccc3)C=C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F11 compound treatment 996552.0 422000.0 0.6 1035384.0 445000.0 0.62 0.8634 0.9999 2072914 Maybridge1_006633 CCC(=O)Nc1cc(C)cc(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F12 compound treatment 981638.0 407000.0 0.58 1026612.0 436000.0 0.61 0.8398 0.9997 1246126 Maybridge1_006634 NC(=O)CC1(CC2CC3CC(C2)C1)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F13 compound treatment 1033377.0 459000.0 0.65 999077.0 409000.0 0.57 0.8646 0.9977 2072915 Maybridge1_006635 CCCCCC(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F14 compound treatment 1071934.0 498000.0 0.71 1069488.0 479000.0 0.67 0.9728 0.9996 1441808 Maybridge1_006636 Oc1c(c2ccccc2)c(=O)n3CCCc4cccc1c43 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F15 compound treatment 1010304.0 436000.0 0.62 1014177.0 424000.0 0.59 0.8563 0.9997 1565903 Maybridge1_006637 CC(C)(C)OC(=O)C(C)(C)Sc1nc(c(o1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F16 compound treatment 977357.0 403000.0 0.57 1034495.0 444000.0 0.62 0.8432 0.9993 2072916 Maybridge1_006638 CC(C)(C)OC(=O)N[C@@H](CCCNC(=N)N)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F17 compound treatment 1010885.0 437000.0 0.62 1027833.0 437000.0 0.61 0.8704 1.0 1378454 Maybridge1_006639 Cc1ccc(Sc2ncccc2n3cccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F18 compound treatment 957830.0 384000.0 0.55 1033656.0 443000.0 0.62 0.8228 0.9981 1185730 Maybridge1_006640 O=C1N(CC2(CCC=CC2)C#N)c3ccccc3C41OCCO4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F19 compound treatment 995246.0 421000.0 0.6 1051425.0 461000.0 0.64 0.8779 0.9994 2072917 Maybridge1_006641 CCOC(=O)CSc1nc2cc(Cl)ccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F20 compound treatment 971935.0 398000.0 0.57 1051005.0 460000.0 0.64 0.8541 0.998 2072918 Maybridge1_006642 CNS(=O)(=O)Cc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F21 compound treatment 977989.0 404000.0 0.57 1087446.0 497000.0 0.69 0.8961 0.9956 2072919 Maybridge1_006643 Cc1[nH]c(=O)c(C#N)c(C)c1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F22 compound treatment 903459.0 329000.0 0.47 1001886.0 411000.0 0.57 0.7368 0.9949 2072920 Maybridge1_006644 CC(C)(NO)C(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F23 mock treatment 928299.0 354000.0 0.5 977999.0 387000.0 0.54 0.7382 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 F24 mock treatment 159015.0 -415000.0 -0.59 153976.0 -437000.0 -0.61 -0.848 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G01 compound treatment 826703.0 252000.0 0.36 809352.0 219000.0 0.31 0.4697 0.9967 1576730 Maybridge1_006645 Nc1nnc(SCC(=O)Nc2ccc3OCOc3c2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G02 compound treatment 836712.0 262000.0 0.37 848499.0 258000.0 0.36 0.5184 0.9998 1130064 Maybridge1_006646 COc1ccccc1N2CCN(CC(C)N(C(=O)C3CCCCC3)c4ccccn4)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G03 compound treatment 888102.0 314000.0 0.45 902799.0 312000.0 0.44 0.6236 0.9999 2072921 Maybridge1_006647 Clc1cccc(SCc2cccc3ccccc23)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G04 compound treatment 900761.0 327000.0 0.46 926037.0 336000.0 0.47 0.6592 1.0 2072922 Maybridge1_006648 Cc1ccc(OCc2nnc(S)n2c3ccccc3)c4CCCc41 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G05 compound treatment 804687.0 230000.0 0.33 950355.0 360000.0 0.5 0.5866 0.9787 2072923 Maybridge1_006649 COc1ccccc1C2CCN(CC2)C(=O)c3ccccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G06 compound treatment 870810.0 297000.0 0.42 907160.0 317000.0 0.44 0.6105 0.9997 2072924 Maybridge1_006650 Cc1ccc(OCc2nnc(SCC(=O)Nc3cccc4OCOc43)n2c5ccccc5)c6CCCc61 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G07 compound treatment 888764.0 315000.0 0.45 964990.0 374000.0 0.52 0.6856 0.997 1072142 Maybridge1_006651 C1COC2(CCC3(CC2)OCCO3)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G08 compound treatment 866644.0 292000.0 0.42 934733.0 344000.0 0.48 0.6335 0.9974 2072925 Maybridge1_006652 Cc1ccc(OCc2nnc(SCC(=O)c3ccc(cc3)[N+](=O)[O-])n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G09 compound treatment 917650.0 343000.0 0.49 1012987.0 422000.0 0.59 0.762 0.9956 1059089 Maybridge1_006653 O=C1NNC(C1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G10 compound treatment 848616.0 274000.0 0.39 882808.0 292000.0 0.41 0.5642 0.9998 2072926 Maybridge1_006654 [O-][N+](=O)c1cc(Cl)c(cc1N2CCCCC2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G11 compound treatment 925017.0 351000.0 0.5 1003677.0 413000.0 0.58 0.7602 0.9974 2072927 Maybridge1_006655 [O-][N+](=O)c1cccc(c1)C(=O)Oc2ccc(Oc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G12 compound treatment 867898.0 294000.0 0.42 910135.0 320000.0 0.45 0.6105 0.9995 2072928 Maybridge1_006656 [O-][N+](=O)c1cc(Cl)c(cc1N2CCCC2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G13 compound treatment 891143.0 317000.0 0.45 1030939.0 440000.0 0.61 0.753 0.9884 1573326 Maybridge1_006657 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G14 compound treatment 919644.0 345000.0 0.49 1008763.0 418000.0 0.58 0.7598 0.9963 1433613 Maybridge1_006658 Brc1ccc(cc1)C(=O)c2cc3cc(Br)cc(Br)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G15 compound treatment 1026871.0 453000.0 0.64 1100484.0 510000.0 0.71 0.9581 0.9988 2072929 Maybridge1_006659 [O-][N+](=O)c1ccc(o1)C2NC(=O)c3c4CCCCc4sc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G16 compound treatment 894453.0 320000.0 0.46 994979.0 404000.0 0.56 0.7209 0.9944 2072930 Maybridge1_006660 [O-][N+](=O)c1cccc(c1)c2csc(=Nc3ccccc3)n2c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G17 compound treatment 940652.0 366000.0 0.52 1058005.0 467000.0 0.65 0.8295 0.9938 2072931 Maybridge1_006661 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G18 compound treatment 843892.0 270000.0 0.38 966816.0 376000.0 0.52 0.6423 0.9881 1731945 Maybridge1_006662 COc1cc(CCC(C)N)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G19 compound treatment 933558.0 359000.0 0.51 1008068.0 418000.0 0.58 0.7731 0.9979 2072932 Maybridge1_006663 CC(C)(C)c1ccc(cc1)C(=O)O/N=C/c2ccc3OCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G20 compound treatment 872904.0 299000.0 0.42 991650.0 401000.0 0.56 0.6959 0.9908 1589048 Maybridge1_006664 CCC(=O)Cc1c(C)[nH]c2ccc(OC)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G21 compound treatment 861341.0 287000.0 0.41 905832.0 315000.0 0.44 0.5997 0.9993 2072933 Maybridge1_006665 COc1ccc(NC(=S)NNC(=O)CSCc2cccc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G22 compound treatment 821988.0 248000.0 0.35 982547.0 392000.0 0.55 0.6358 0.9774 1004920 Maybridge1_006666 OC(=O)Cc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G23 mock treatment 865727.0 292000.0 0.41 928522.0 338000.0 0.47 0.6265 0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 G24 mock treatment 146694.0 -428000.0 -0.61 150738.0 -440000.0 -0.61 -0.8636 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H01 compound treatment 855277.0 281000.0 0.4 832268.0 242000.0 0.34 0.521 0.9964 1522882 Maybridge1_006667 Cc1ccc(C)n1c2ccc(cc2)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H02 compound treatment 877266.0 303000.0 0.43 917155.0 327000.0 0.46 0.6269 0.9996 2072934 Maybridge1_006668 COc1ccc(cc1)C(=O)COc2nc(cc(c2C#N)C(F)(F)F)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H03 compound treatment 959783.0 386000.0 0.55 956985.0 366000.0 0.51 0.7491 0.9994 2072935 Maybridge1_006669 Cc1ccc(cc1)S(=O)(=O)NCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H04 compound treatment 918034.0 344000.0 0.49 942194.0 352000.0 0.49 0.6926 1.0 2072936 Maybridge1_006670 CCOC(=O)/C(=C/Nc1ccc2OCOc2c1)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H05 compound treatment 934615.0 360000.0 0.51 965676.0 375000.0 0.52 0.7324 0.9999 2072937 Maybridge1_006671 Cc1onc(c1C(=O)NCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H06 compound treatment 804765.0 231000.0 0.33 846852.0 256000.0 0.36 0.4846 0.9991 2072938 Maybridge1_006672 CC1(C)N=c2ccc(cc2=N1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H07 compound treatment 956426.0 382000.0 0.54 1046061.0 456000.0 0.64 0.8336 0.997 2072939 Maybridge1_006673 Cc1ccc(C)n1c2ccc(cc2)C(=O)NNS(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H08 compound treatment 926233.0 352000.0 0.5 905695.0 315000.0 0.44 0.6648 0.9979 1147764 Maybridge1_006674 COC(=O)c1cccnc1Sc2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H09 compound treatment 965665.0 391000.0 0.56 1034085.0 444000.0 0.62 0.8311 0.9986 1479714 Maybridge1_006675 COc1ccc(cc1OC)C(=O)Nc2cccnc2Oc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H10 compound treatment 904702.0 330000.0 0.47 929058.0 339000.0 0.47 0.6662 1.0 2072940 Maybridge1_006676 O=C(N/N=C/1\C(=O)Nc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H11 compound treatment 959163.0 385000.0 0.55 1043754.0 453000.0 0.63 0.8341 0.9974 1528049 Maybridge1_006677 CCC(=O)Nc1cc(OC)cc(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H12 compound treatment 944443.0 370000.0 0.53 1008626.0 418000.0 0.58 0.7846 0.9987 2072941 Maybridge1_006678 OC(=O)C1(CC2CC3C1)CC(C2)(C3)c4ccc(cc4)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H13 compound treatment 934796.0 361000.0 0.51 1018316.0 428000.0 0.6 0.7845 0.9972 1468197 Maybridge1_006679 Clc1ccc(Oc2ncccc2NS(=O)(=O)c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H14 compound treatment 944388.0 370000.0 0.53 1027242.0 437000.0 0.61 0.8029 0.9974 1264289 Maybridge1_006680 COc1ccc2c(O)c(Cc3ccccc3)c(=O)[nH]c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H15 compound treatment 966314.0 392000.0 0.56 1031413.0 441000.0 0.61 0.8291 0.9988 2072942 Maybridge1_006681 Cc1nc(cn1CC=C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H16 compound treatment 903872.0 330000.0 0.47 982087.0 392000.0 0.55 0.7177 0.9971 2072943 Maybridge1_006682 N[C@@H](Cc1ccc(cc1)[N+](=O)[O-])C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H17 compound treatment 958620.0 384000.0 0.55 1024063.0 434000.0 0.6 0.8141 0.9987 2072944 Maybridge1_006683 Cc1nc(cn1CC(=O)c2ccccc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H18 compound treatment 905517.0 331000.0 0.47 991089.0 401000.0 0.56 0.7282 0.9964 2072945 Maybridge1_006684 COC(=O)C(C)(N)Cc1c[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H19 compound treatment 973749.0 400000.0 0.57 1014988.0 424000.0 0.59 0.8204 0.9998 2072946 Maybridge1_006685 CN(C(=O)CN1CCN(CC1)c2cc(C)nc3ccccc23)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H20 compound treatment 847432.0 273000.0 0.39 973788.0 383000.0 0.53 0.6527 0.9877 1224541 Maybridge1_006686 O=C1CN=C(c2ccccc2)c3ccccc3N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H21 compound treatment 973249.0 399000.0 0.57 1055252.0 465000.0 0.65 0.8596 0.9978 2072947 Maybridge1_006687 Cc1cc(N2CCN(CC(=O)c3ccccc3)CC2)c4ccccc4n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H22 compound treatment 884209.0 310000.0 0.44 945720.0 355000.0 0.5 0.662 0.9983 1340087 Maybridge1_006688 Cc1cc2c(N)cccc2nn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H23 mock treatment 902698.0 328000.0 0.47 955963.0 365000.0 0.51 0.6907 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 H24 mock treatment 146767.0 -427000.0 -0.61 171431.0 -419000.0 -0.58 -0.8431 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I01 compound treatment 833274.0 259000.0 0.37 824255.0 234000.0 0.33 0.491 0.9981 2072948 Maybridge1_006689 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(C)cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I02 compound treatment 884702.0 310000.0 0.44 870136.0 280000.0 0.39 0.588 0.9981 2072949 Maybridge1_006690 Cc1cnc2CCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I03 compound treatment 908047.0 334000.0 0.47 965994.0 375000.0 0.52 0.706 0.9988 1290694 Maybridge1_006691 COc1ccccc1C2CCN(CC2)C(=O)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I04 compound treatment 900375.0 326000.0 0.46 968882.0 378000.0 0.53 0.7011 0.9979 2072950 Maybridge1_006692 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I05 compound treatment 927674.0 353000.0 0.5 994262.0 404000.0 0.56 0.7536 0.9984 1611583 Maybridge1_006693 COc1ccccc1C2CCN(CC2)C(=O)c3ccccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I06 compound treatment 899963.0 326000.0 0.46 964373.0 374000.0 0.52 0.6963 0.9983 2072951 Maybridge1_006694 CCc1cc2c(cc1C(=O)CSc3nnc(COc4ccc(C)c5CCCc54)n3c6ccccc6)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I07 compound treatment 936628.0 362000.0 0.52 963959.0 373000.0 0.52 0.7327 1.0 2072952 Maybridge1_006695 Fc1ccc(CCc2ccc(F)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I08 compound treatment 920002.0 346000.0 0.49 939526.0 349000.0 0.49 0.6919 1.0 2072953 Maybridge1_006696 Cc1ccc(OCc2nnc(SCC(=O)c3ccc(F)cc3)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I09 compound treatment 879047.0 305000.0 0.43 1016280.0 426000.0 0.59 0.7264 0.988 1226641 Maybridge1_006697 O=C1CCCc2nc3CCCC(=O)c3cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I10 compound treatment 903475.0 329000.0 0.47 970646.0 380000.0 0.53 0.706 0.9981 1616269 Maybridge1_006698 Cc1ccc(C)c2c(O)c(cnc12)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I11 compound treatment 913770.0 340000.0 0.48 983998.0 393000.0 0.55 0.7295 0.998 1571873 Maybridge1_006699 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I12 compound treatment 874431.0 300000.0 0.43 991251.0 401000.0 0.56 0.6971 0.9912 2072954 Maybridge1_006700 COc1ccc(cc1)C(=O)c2cc3cc(ccc3o2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I13 compound treatment 923955.0 350000.0 0.5 990692.0 400000.0 0.56 0.7463 0.9983 2072955 Maybridge1_006701 Fc1ccc(cc1)C(=O)NNC(=O)CSCc2cccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I14 compound treatment 901089.0 327000.0 0.46 1042199.0 452000.0 0.63 0.7741 0.9888 1342049 Maybridge1_006702 Clc1cc(Cl)c2oc(cc2c1)C(=O)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I15 compound treatment 912096.0 338000.0 0.48 1007384.0 417000.0 0.58 0.7509 0.9955 2072956 Maybridge1_006703 Cc1nnc(Sc2ccc([N+](=O)[O-])c(Sc3nnc(C)s3)n2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I16 compound treatment 918681.0 344000.0 0.49 1008341.0 418000.0 0.58 0.7584 0.9963 2072957 Maybridge1_006704 [O-][N+](=O)c1cc(Cl)c(cc1SCc2ccc(Cl)cc2Cl)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I17 compound treatment 947761.0 374000.0 0.53 1043867.0 453000.0 0.63 0.8227 0.9962 1731945 Maybridge1_006705 COc1cc(CCC(C)N)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I18 compound treatment 904897.0 331000.0 0.47 957165.0 367000.0 0.51 0.6941 0.9991 2072958 Maybridge1_006706 OC(c1cc2cc(ccc2o1)[N+](=O)[O-])c3ccc(cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I19 compound treatment 889543.0 315000.0 0.45 992209.0 402000.0 0.56 0.7132 0.9939 1682780 Maybridge1_006707 CCOC(=O)c1c[nH]c2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I20 compound treatment 903899.0 330000.0 0.47 985305.0 395000.0 0.55 0.7209 0.9968 2072959 Maybridge1_006708 OS(=O)(=O)c1ccc(Nc2ncnc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I21 compound treatment 911992.0 338000.0 0.48 992525.0 402000.0 0.56 0.7361 0.997 2072960 Maybridge1_006709 CCCCc1ccc(NC(=S)NNC(=O)CSCc2cccc3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I22 compound treatment 876159.0 302000.0 0.43 955451.0 365000.0 0.51 0.6635 0.9964 1020457 Maybridge1_006710 OC(=O)c1ccccc1C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I23 mock treatment 915138.0 341000.0 0.48 978583.0 388000.0 0.54 0.7255 0.9985 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 I24 mock treatment 144871.0 -429000.0 -0.61 148685.0 -442000.0 -0.62 -0.8675 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J01 compound treatment 856892.0 283000.0 0.4 819874.0 229000.0 0.32 0.5104 0.9936 1719291 Maybridge1_006711 COc1cc(Br)cc2cc(C(=O)O)c(=O)oc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J02 compound treatment 855754.0 282000.0 0.4 937537.0 347000.0 0.48 0.6253 0.9956 2072961 Maybridge1_006712 FC(F)(F)c1cc(nc(OCC(=O)c2ccc(Cl)cc2)c1C#N)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J03 compound treatment 921347.0 347000.0 0.49 933813.0 343000.0 0.48 0.6876 0.9999 2072962 Maybridge1_006713 CC(=O)OCc1cc(/C=N/N(C(=O)C)c2ccccc2)nn1c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J04 compound treatment 898958.0 325000.0 0.46 942497.0 352000.0 0.49 0.6737 0.9995 1464724 Maybridge1_006714 COc1ccc(cc1)C(=O)COc2ccc(C)cc2NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J05 compound treatment 817174.0 243000.0 0.35 926793.0 336000.0 0.47 0.5759 0.9887 2072963 Maybridge1_006715 CC(=O)C(=NNc1ccc(C)cc1[N+](=O)[O-])C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J06 compound treatment 889617.0 315000.0 0.45 894794.0 304000.0 0.42 0.6172 0.9996 1626134 Maybridge1_006716 Cc1ccc2cc(NC(=O)c3ccco3)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J07 compound treatment 940652.0 366000.0 0.52 989374.0 399000.0 0.56 0.7618 0.9995 2072964 Maybridge1_006717 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2cccnc2Oc3ccccc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J08 compound treatment 894081.0 320000.0 0.45 959535.0 369000.0 0.51 0.6856 0.9981 2072965 Maybridge1_006718 [O-][N+](=O)c1ccc(o1)c2nnc(S)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J09 compound treatment 958828.0 385000.0 0.55 1016012.0 425000.0 0.59 0.8064 0.9992 1362612 Maybridge1_006719 Clc1ccc(Oc2ncccc2NC(=O)c3cccc4ccccc34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J10 compound treatment 873734.0 300000.0 0.43 984069.0 394000.0 0.55 0.6893 0.9921 2072966 Maybridge1_006720 OC(=O)C1CC1(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J11 compound treatment 992096.0 418000.0 0.59 1039619.0 449000.0 0.63 0.8631 0.9997 2072967 Maybridge1_006721 Cc1ccc(C)n1c2ccc(cc2)C(=O)NNC(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J12 compound treatment 906154.0 332000.0 0.47 978099.0 388000.0 0.54 0.716 0.9977 2072968 Maybridge1_006722 OC1(CCN(Cc2ccccc2)CC1)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J13 compound treatment 924388.0 350000.0 0.5 969339.0 379000.0 0.53 0.7257 0.9996 2072969 Maybridge1_006723 CCCCCc1ccc(cc1)S(=O)(=O)Nc2cccnc2Oc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J14 compound treatment 938560.0 364000.0 0.52 1017319.0 427000.0 0.6 0.7873 0.9976 1060930 Maybridge1_006724 CCCC(NC(=O)CN)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J15 compound treatment 922102.0 348000.0 0.49 995750.0 405000.0 0.57 0.7495 0.9978 1319787 Maybridge1_006725 Cc1ccc(C)n1c2cccnc2Sc3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J16 compound treatment 887343.0 313000.0 0.45 986050.0 396000.0 0.55 0.7049 0.9944 1320822 Maybridge1_006726 Clc1ccc(cc1)C2C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J17 compound treatment 932206.0 358000.0 0.51 1029543.0 439000.0 0.61 0.7929 0.9958 2072970 Maybridge1_006727 COc1ccc(cc1)C(=O)Cn2cc(nc2C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J18 compound treatment 881101.0 307000.0 0.44 956170.0 366000.0 0.51 0.6692 0.997 1369467 Maybridge1_006728 COC(=O)CCC1CC2(CCC1=O)OCCO2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J19 compound treatment 857844.0 284000.0 0.4 1012019.0 422000.0 0.59 0.7009 0.9831 2072971 Maybridge1_006729 CCOC(=O)COc1nc(C)cc(c1C#N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J20 compound treatment 909089.0 335000.0 0.48 958905.0 368000.0 0.51 0.7 0.9993 1331647 Maybridge1_006730 CC1(C)C2CCC1(C)C(C2)NC(=O)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J21 compound treatment 928139.0 354000.0 0.5 1007027.0 417000.0 0.58 0.7667 0.9974 2072972 Maybridge1_006731 Nc1nnc(SCCCCOC2CCCCO2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J22 compound treatment 897321.0 323000.0 0.46 979129.0 389000.0 0.54 0.7081 0.9966 2072973 Maybridge1_006732 Cc1cc2-c3nonc3CCc2nn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J23 mock treatment 927176.0 353000.0 0.5 1000402.0 410000.0 0.57 0.7591 0.9979 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 J24 mock treatment 154206.0 -420000.0 -0.6 161048.0 -429000.0 -0.6 -0.8459 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K01 compound treatment 820627.0 246000.0 0.35 815449.0 225000.0 0.31 0.4696 0.9985 2072974 Maybridge1_006733 COc1ccc(OS(=O)(=O)c2ccc(C)cc2)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K02 compound treatment 833872.0 260000.0 0.37 852632.0 262000.0 0.37 0.5196 1.0 1205178 Maybridge1_006734 N#Cc1ccc2[nH]cc(CCN(Cc3ccccc3)Cc4ccccc4)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K03 compound treatment 890551.0 316000.0 0.45 922807.0 332000.0 0.46 0.6458 0.9999 1727215 Maybridge1_006735 COc1ccccc1C2CCN(CC2)C(=O)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K04 compound treatment 871031.0 297000.0 0.42 931334.0 341000.0 0.48 0.6346 0.9982 2072975 Maybridge1_006736 [O-][N+](=O)/C=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K05 compound treatment 868336.0 294000.0 0.42 926944.0 336000.0 0.47 0.6275 0.9984 2072976 Maybridge1_006737 COC(=O)C1Cc2c([nH]c3ccccc23)C4(CCN(C)CC4)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K06 compound treatment 836595.0 262000.0 0.37 853756.0 263000.0 0.37 0.5234 1.0 2072977 Maybridge1_006738 Cc1ccc(OCc2nnc(SCC(=O)NCc3ccccc3)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K07 compound treatment 891266.0 317000.0 0.45 991050.0 401000.0 0.56 0.7138 0.9943 2072949 Maybridge1_006739 Cc1cnc2CCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K08 compound treatment 838841.0 265000.0 0.38 925790.0 335000.0 0.47 0.5967 0.9942 2072978 Maybridge1_006740 Cc1ccc(OCc2nnc(SCC(=O)c3ccccc3)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K09 compound treatment 904575.0 330000.0 0.47 992362.0 402000.0 0.56 0.7285 0.9961 1702857 Maybridge1_006741 Cc1cccc(NC(=O)c2cccc3ccccc23)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K10 compound treatment 850754.0 277000.0 0.39 968416.0 378000.0 0.53 0.6508 0.9896 2072979 Maybridge1_006742 [O-][N+](=O)c1ccc2oc(cc2c1)C(=O)c3ccc(cc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K11 compound treatment 890477.0 316000.0 0.45 1016997.0 426000.0 0.59 0.7386 0.9905 1540037 Maybridge1_006743 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3ccccc3Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K12 compound treatment 875659.0 301000.0 0.43 963201.0 373000.0 0.52 0.6707 0.9954 2072980 Maybridge1_006744 COc1cc(NC(=O)C)cc(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K13 compound treatment 883400.0 309000.0 0.44 998665.0 408000.0 0.57 0.7134 0.9919 2072981 Maybridge1_006745 COC(=O)C(Cc1c[nH]c2ccccc12)/N=C/c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K14 compound treatment 854565.0 280000.0 0.4 954346.0 364000.0 0.51 0.6407 0.9929 1427936 Maybridge1_006746 Fc1ccc(cc1)C(=O)c2cc3cc(Cl)cc(Cl)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K15 compound treatment 932972.0 359000.0 0.51 1029071.0 439000.0 0.61 0.7933 0.9959 1705365 Maybridge1_006747 CN1CCCC21NCCc3c2[nH]c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K16 compound treatment 903213.0 329000.0 0.47 973239.0 383000.0 0.53 0.7083 0.9978 1024400 Maybridge1_006748 COC(=O)C(N)Cc1c[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K17 compound treatment 926953.0 353000.0 0.5 947119.0 357000.0 0.5 0.7064 1.0 2072982 Maybridge1_006749 O/N=C/1\CCCc2[nH]c3ccccc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K18 compound treatment 910598.0 336000.0 0.48 950944.0 360000.0 0.5 0.6937 0.9997 2072983 Maybridge1_006750 OC(c1cc2cc(ccc2o1)[N+](=O)[O-])c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K19 compound treatment 917711.0 343000.0 0.49 957413.0 367000.0 0.51 0.7072 0.9997 1554526 Maybridge1_006751 Brc1cnc(nc1)N2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K20 compound treatment 901299.0 327000.0 0.47 981050.0 391000.0 0.54 0.714 0.9969 2072984 Maybridge1_006752 Cc1ccc(N/N=C\2/CCCNC2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K21 compound treatment 922552.0 348000.0 0.5 979785.0 389000.0 0.54 0.7342 0.999 2072985 Maybridge1_006753 O=C(CSCc1cccc2ccccc12)NNC(=S)NC3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K22 compound treatment 859762.0 286000.0 0.41 935176.0 345000.0 0.48 0.627 0.9965 1324807 Maybridge1_006754 O=C(C1CCCCC1)N2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K23 mock treatment 907585.0 333000.0 0.47 966497.0 376000.0 0.52 0.706 0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 K24 mock treatment 172647.0 -402000.0 -0.57 155600.0 -435000.0 -0.61 -0.8327 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L01 compound treatment 829701.0 255000.0 0.36 838862.0 248000.0 0.35 0.5018 0.9997 1004718 Maybridge1_006755 OC(=O)Cc1c[nH]c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L02 compound treatment 836712.0 262000.0 0.37 869250.0 279000.0 0.39 0.5388 0.9998 2072986 Maybridge1_006756 COc1ccc(cc1)C(=O)COc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L03 compound treatment 888871.0 315000.0 0.45 951798.0 361000.0 0.5 0.6727 0.9982 1921262 Maybridge1_006757 O=C(NNC(=O)c1ccccc1)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L04 compound treatment 867805.0 294000.0 0.42 919678.0 329000.0 0.46 0.6198 0.9989 2072987 Maybridge1_006758 COc1ccc(C=C2C(=O)OC(C)(C)OC2=O)c(Cl)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L05 compound treatment 880266.0 306000.0 0.44 939463.0 349000.0 0.49 0.6519 0.9984 2072988 Maybridge1_006759 [O-][N+](=O)c1cc(ccc1NCCNS(=O)(=O)c2ccc3ccccc3c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L06 compound treatment 888503.0 314000.0 0.45 883729.0 293000.0 0.41 0.6052 0.999 1687379 Maybridge1_006760 Cc1ccc2cc(NC(=O)c3cccs3)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L07 compound treatment 904864.0 331000.0 0.47 975619.0 385000.0 0.54 0.7123 0.9978 2072989 Maybridge1_006761 CCCc1ccc(cc1)C(=O)NNC(=O)c2ccc(cc2)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L08 compound treatment 596000.0 21800.0 0.03 645747.0 55200.0 0.08 0.0764 0.9198 2072990 Maybridge1_006762 Sc1nnc2nc(c3ccccc3)c(nn12)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L09 compound treatment 881744.0 308000.0 0.44 898556.0 308000.0 0.43 0.613 1.0 1360230 Maybridge1_006763 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3ccco3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L10 compound treatment 883511.0 309000.0 0.44 954556.0 364000.0 0.51 0.67 0.9974 2072991 Maybridge1_006764 CC(=O)c1ccc(cc1)C2CC2(Cl)Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L11 compound treatment 917433.0 343000.0 0.49 999130.0 409000.0 0.57 0.7481 0.997 1505726 Maybridge1_006765 CC(C)(C)OC(=O)C(C)(C)Sc1nnc(N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L12 compound treatment 839118.0 265000.0 0.38 971935.0 381000.0 0.53 0.6425 0.9857 1005800 Maybridge1_006766 Cc1ccc2cccc(Cl)c2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L13 compound treatment 894552.0 320000.0 0.46 983407.0 393000.0 0.55 0.7096 0.9958 2072992 Maybridge1_006767 NC(=O)c1ccccc1NC(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L14 compound treatment 852188.0 278000.0 0.4 1002480.0 412000.0 0.57 0.6858 0.9833 1050132 Maybridge1_006768 NCC(=O)NC(Cc1ccccc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L15 compound treatment 901762.0 328000.0 0.47 1041603.0 451000.0 0.63 0.7742 0.9891 1424974 Maybridge1_006769 CCOC(=O)c1ccc2nc(cc(O)c2c1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L16 compound treatment 891735.0 318000.0 0.45 987783.0 397000.0 0.55 0.7111 0.9948 2072993 Maybridge1_006770 OC1=C(C(=O)c2ccccc12)c3ccc(Br)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L17 compound treatment 857030.0 283000.0 0.4 941084.0 351000.0 0.49 0.6301 0.9953 1433410 Maybridge1_006771 Cc1cc(N2CCNCC2)c3ccccc3n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L18 compound treatment 867199.0 293000.0 0.42 961091.0 371000.0 0.52 0.6601 0.9943 2072994 Maybridge1_006772 CC(Nc1ccccc1)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L19 compound treatment 888862.0 315000.0 0.45 971563.0 381000.0 0.53 0.6922 0.9963 2072995 Maybridge1_006773 COc1cccc(c1)c2nnc(o2)c3ccccc3NC(=O)c4ccc(F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L20 compound treatment 887441.0 313000.0 0.45 1000122.0 410000.0 0.57 0.7189 0.9924 1406897 Maybridge1_006774 CC(C)(C)c1ccc(cc1)C(=O)NC2CC3CCC2(C)C3(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L21 compound treatment 930894.0 357000.0 0.51 1020975.0 430000.0 0.6 0.7832 0.9965 2072996 Maybridge1_006775 CC(O)c1sc(nc1C)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L22 compound treatment 841869.0 268000.0 0.38 912613.0 322000.0 0.45 0.5868 0.9966 1614912 Maybridge1_006776 C1Cc2nnc(cc2-c3nonc13)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L23 mock treatment 876956.0 303000.0 0.43 950625.0 360000.0 0.5 0.6596 0.9971 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 L24 mock treatment 146023.0 -428000.0 -0.61 156941.0 -434000.0 -0.6 -0.8582 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M01 compound treatment 811706.0 237000.0 0.34 816691.0 226000.0 0.32 0.4619 0.9994 2072997 Maybridge1_006777 COS(=O)(=O)c1ccc2C(=O)CC(C)(C)Oc2c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M02 compound treatment 772658.0 198000.0 0.28 822710.0 232000.0 0.32 0.4285 0.9976 2072998 Maybridge1_006778 FC(F)(F)Oc1ccc(cc1)n2c(S)nnc2CSCc3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M03 compound treatment 900274.0 326000.0 0.46 920338.0 330000.0 0.46 0.6531 1.0 1048869 Maybridge1_006779 Cc1cc(OCc2ccccc2)ccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M04 compound treatment 835271.0 261000.0 0.37 868781.0 278000.0 0.39 0.5369 0.9998 2072999 Maybridge1_006780 CC1=NN(C(=O)C1)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M05 compound treatment 881648.0 307000.0 0.44 888625.0 298000.0 0.42 0.6031 0.9997 2073000 Maybridge1_006781 CCOC(CN(Cc1ccc(OC)c(OS(=O)(=O)c2ccc(C)cc2)c1)S(=O)(=O)c3ccc(C)cc3)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M06 compound treatment 839650.0 265000.0 0.38 937602.0 347000.0 0.48 0.6092 0.9924 2073001 Maybridge1_006782 Cc1ccc(OCc2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M07 compound treatment 872991.0 299000.0 0.42 999687.0 409000.0 0.57 0.704 0.9894 1287839 Maybridge1_006783 CN1C2CCC1CC(=NO)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M08 compound treatment 845430.0 271000.0 0.39 890608.0 300000.0 0.42 0.5687 0.9992 2073002 Maybridge1_006784 CSc1nnc(COc2ccc(C)c3CCCc32)n1c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M09 compound treatment 854618.0 280000.0 0.4 945617.0 355000.0 0.5 0.6322 0.9942 1652203 Maybridge1_006785 Fc1ccc(CN2CCC(CC2)NC(=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M10 compound treatment 849483.0 275000.0 0.39 948869.0 358000.0 0.5 0.6302 0.9927 2073003 Maybridge1_006786 [O-][N+](=O)c1ccc2oc(cc2c1)C(=O)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M11 compound treatment 917589.0 343000.0 0.49 967863.0 377000.0 0.53 0.7174 0.9993 1134551 Maybridge1_006787 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccc(OC)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M12 compound treatment 854307.0 280000.0 0.4 938567.0 348000.0 0.49 0.6249 0.9952 2073004 Maybridge1_006788 [O-][N+](=O)c1cccc(c1)C(=O)c2cc3cc(Br)cc(Br)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M13 compound treatment 882485.0 308000.0 0.44 968416.0 378000.0 0.53 0.6827 0.9958 2073005 Maybridge1_006789 CC/1(C)C2CC[C@](C)(C2)\C1=N\O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M14 compound treatment 861204.0 287000.0 0.41 968126.0 378000.0 0.53 0.661 0.9921 1223857 Maybridge1_006790 Clc1ccc(cc1)C(=O)c2cc3cc(Cl)cc(Cl)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M15 compound treatment 920319.0 346000.0 0.49 1017736.0 427000.0 0.6 0.7693 0.9955 1337456 Maybridge1_006791 CC(C)(C)NC(=O)N1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M16 compound treatment 861941.0 288000.0 0.41 966351.0 376000.0 0.52 0.66 0.9925 2073006 Maybridge1_006792 [O-][N+](=O)c1cc(Cl)c(cc1SCc2ccc(Cl)c(Cl)c2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M17 compound treatment 941211.0 367000.0 0.52 1011310.0 421000.0 0.59 0.784 0.9983 1427039 Maybridge1_006793 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(N)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M18 compound treatment 876597.0 302000.0 0.43 960002.0 369000.0 0.52 0.6684 0.996 2073007 Maybridge1_006794 CCOC(=O)c1ccc(cc1)n2c(C)ccc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M19 compound treatment 914452.0 340000.0 0.48 1028490.0 438000.0 0.61 0.7741 0.9933 2073008 Maybridge1_006795 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(Oc4c(Cl)cccc4[N+](=O)[O-])cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M20 compound treatment 844025.0 270000.0 0.38 942506.0 352000.0 0.49 0.6184 0.9926 1248044 Maybridge1_006796 CC(Nc1ccccn1)C(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M21 compound treatment 911372.0 337000.0 0.48 1002396.0 412000.0 0.57 0.7452 0.996 1364670 Maybridge1_006797 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M22 compound treatment 876358.0 302000.0 0.43 948003.0 357000.0 0.5 0.6564 0.9973 1495828 Maybridge1_006798 O=C1N(CCC#N)c2ccccc2C31OCCO3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M23 mock treatment 871077.0 297000.0 0.42 979189.0 389000.0 0.54 0.6818 0.9924 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 M24 mock treatment 692359.0 118000.0 0.17 723462.0 133000.0 0.19 0.2499 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N01 compound treatment 832886.0 259000.0 0.37 851979.0 261000.0 0.36 0.518 1.0 2073009 Maybridge1_006799 CC(=O)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N02 compound treatment 851805.0 278000.0 0.39 902023.0 312000.0 0.43 0.5863 0.9989 2073010 Maybridge1_006800 Cc1c(sc2ccc(Cl)cc12)C(=O)COc3nc(cc(c3C#N)C(F)(F)F)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N03 compound treatment 886928.0 313000.0 0.44 932107.0 342000.0 0.48 0.6513 0.9994 2073011 Maybridge1_006801 Cc1ccc(C)n1c2ccc(cc2)c3nnc(S)n3c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N04 compound treatment 867703.0 293000.0 0.42 878223.0 288000.0 0.4 0.5789 0.9998 1218710 Maybridge1_006802 Cc1c(oc2ccc3ccccc3c12)C(=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N05 compound treatment 994805.0 421000.0 0.6 1021656.0 431000.0 0.6 0.8481 1.0 2073012 Maybridge1_006803 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N06 compound treatment 851272.0 277000.0 0.39 921812.0 331000.0 0.46 0.6053 0.9969 1505499 Maybridge1_006804 OC(=O)c1cc2c(Cl)cc(Cl)cc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N07 compound treatment 894845.0 321000.0 0.46 926135.0 336000.0 0.47 0.6534 0.9999 1384754 Maybridge1_006805 CCCc1ccc(cc1)C(=O)Nc2cccnc2Oc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N08 compound treatment 822857.0 249000.0 0.35 912051.0 322000.0 0.45 0.5671 0.9931 2073013 Maybridge1_006806 CCSC(SCC)[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N09 compound treatment 878655.0 304000.0 0.43 943436.0 353000.0 0.49 0.6542 0.998 1138325 Maybridge1_006807 CCCc1ccc(cc1)C(=O)Nc2cccnc2Oc3ccc(OC)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N10 compound treatment 890633.0 316000.0 0.45 928970.0 338000.0 0.47 0.652 0.9997 1187040 Maybridge1_006808 C(c1nc2ccccc2s1)c3nc4ccccc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N11 compound treatment 903399.0 329000.0 0.47 971475.0 381000.0 0.53 0.7067 0.998 1051542 Maybridge1_006809 CC1(CC2CC1C=C2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N12 compound treatment 856042.0 282000.0 0.4 955111.0 365000.0 0.51 0.643 0.9931 864479 Maybridge1_006810 COc1cc(CC(N)C(=O)O)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N13 compound treatment 863313.0 289000.0 0.41 965116.0 375000.0 0.52 0.6601 0.993 1194173 Maybridge1_006811 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3cccc4ccccc34)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N14 compound treatment 826781.0 253000.0 0.36 910778.0 320000.0 0.45 0.5698 0.9942 2073014 Maybridge1_006812 NCC(=O)NCC(=O)NCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N15 compound treatment 889853.0 316000.0 0.45 980362.0 390000.0 0.54 0.7019 0.9955 2073015 Maybridge1_006813 [O-][N+](=O)c1cc(Cl)c(cc1Sc2nc(c(o2)c3ccccc3)c4ccccc4)n5cccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N16 compound treatment 758563.0 184000.0 0.26 810643.0 220000.0 0.31 0.4025 0.9969 2073016 Maybridge1_006814 OC1=C(C(=O)c2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N17 compound treatment 905780.0 332000.0 0.47 1005276.0 415000.0 0.58 0.7424 0.9949 1375532 Maybridge1_006815 Nn1c(cc(c(C#N)c1=O)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N18 compound treatment 864070.0 290000.0 0.41 953970.0 363000.0 0.51 0.6499 0.9947 1477161 Maybridge1_006816 COc1ccccc1N2CCN(CC2)C(=O)C(C)Nc3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N19 compound treatment 887384.0 313000.0 0.45 984400.0 394000.0 0.55 0.7034 0.9946 2073017 Maybridge1_006817 Fc1ccc(cc1)C(=O)Nc2ccccc2c3nnc(o3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N20 compound treatment 866831.0 293000.0 0.42 957100.0 367000.0 0.51 0.6558 0.9948 1368775 Maybridge1_006818 CC1(C)C2CCC1(C)C(C2)NC(=O)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N21 compound treatment 890839.0 317000.0 0.45 1024746.0 434000.0 0.61 0.7466 0.9893 1177559 Maybridge1_006819 CCN(CC)c1ccc2cc(C(=O)O)c(=O)oc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N22 compound treatment 881342.0 307000.0 0.44 987177.0 397000.0 0.55 0.7 0.9931 2073018 Maybridge1_006820 Cc1cc(cnn1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N23 mock treatment 900803.0 327000.0 0.46 962989.0 372000.0 0.52 0.6957 0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 N24 mock treatment 703742.0 130000.0 0.18 776017.0 186000.0 0.26 0.3132 0.9861 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O01 compound treatment 820626.0 246000.0 0.35 810711.0 220000.0 0.31 0.4649 0.9978 1664938 Maybridge1_006821 Cc1c(OCC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3Cl)ccc4C(=O)CC(C)(C)Oc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O02 compound treatment 799740.0 226000.0 0.32 832512.0 242000.0 0.34 0.4654 0.9997 1466695 Maybridge1_006822 O=C(Cc1ccccc1)N2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O03 compound treatment 865728.0 292000.0 0.41 866715.0 276000.0 0.39 0.5655 0.9993 1641395 Maybridge1_006823 COc1cc(ccc1O)C(=O)c2cc(Cl)ccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O04 compound treatment 839842.0 266000.0 0.38 861718.0 271000.0 0.38 0.5346 1.0 2073019 Maybridge1_006824 CCc1ccc(NC(=O)/C=C/c2ccc(N3CCC(CC3)c4ccccc4OC)c(c2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O05 compound treatment 861126.0 287000.0 0.41 893832.0 303000.0 0.42 0.5876 0.9998 2073020 Maybridge1_006825 [O-][N+](=O)c1cc(Cl)ccc1NCNc2ccc(Cl)cc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O06 compound treatment 805874.0 232000.0 0.33 820500.0 230000.0 0.32 0.4598 0.9999 2073021 Maybridge1_006826 CCOC(=O)CSc1cc(c(Cl)cc1[N+](=O)[O-])n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O07 compound treatment 879119.0 305000.0 0.43 920748.0 330000.0 0.46 0.6323 0.9995 2073022 Maybridge1_006827 OC(=O)C1=CN(C2CCCCC2)c3ccccc3C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O08 compound treatment 823095.0 249000.0 0.35 833339.0 243000.0 0.34 0.4897 0.9998 2073023 Maybridge1_006828 Cc1ccc(Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c3CCCc31 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O09 compound treatment 889051.0 315000.0 0.45 898022.0 308000.0 0.43 0.6198 0.9998 2073024 Maybridge1_006829 COC(=O)C1Cc2c([nH]c3ccccc23)C4(CCN(Cc5ccccc5)CC4)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O10 compound treatment 842206.0 268000.0 0.38 839679.0 249000.0 0.35 0.5152 0.9989 2073025 Maybridge1_006830 Cc1ccc(OCc2nnc(SCc3c(F)cccc3Cl)n2c4ccccc4)c5CCCc51 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O11 compound treatment 902141.0 328000.0 0.47 873267.0 283000.0 0.39 0.6086 0.9965 1454277 Maybridge1_006831 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3cccc(Br)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O12 compound treatment 826795.0 253000.0 0.36 868172.0 278000.0 0.39 0.5278 0.9993 1385820 Maybridge1_006832 Fc1ccc(cc1)C(=O)c2cc3cc(Br)cc(Br)c3o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O13 compound treatment 863784.0 290000.0 0.41 906690.0 316000.0 0.44 0.603 0.9994 2073026 Maybridge1_006833 O/N=C/c1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O14 compound treatment 851551.0 277000.0 0.39 883794.0 293000.0 0.41 0.5681 0.9998 1675089 Maybridge1_006834 Cc1cc(Br)c(OCC(=O)NN)c2CCCc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O15 compound treatment 884093.0 310000.0 0.44 929918.0 339000.0 0.47 0.6463 0.9994 1565927 Maybridge1_006835 CC(C)(C)c1ccc(cc1)N2C(=O)c3cc(Cl)c(Cl)cc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O16 compound treatment 835473.0 261000.0 0.37 868945.0 278000.0 0.39 0.5373 0.9998 2073027 Maybridge1_006836 CN(C)/C(=C\1/N=C(OC1=O)c2ccccc2)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O17 compound treatment 898147.0 324000.0 0.46 924574.0 334000.0 0.47 0.6552 1.0 1255675 Maybridge1_006837 O=C(NC1CCN(Cc2c[nH]c3ccccc23)CC1)C4CCCCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O18 compound treatment 847424.0 273000.0 0.39 873560.0 283000.0 0.39 0.5539 1.0 2073028 Maybridge1_006838 Cc1ccc(cc1)S(=O)(=O)Nc2cc(ccc2Oc3ccc(C)c4CCCc43)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O19 compound treatment 873323.0 299000.0 0.43 918288.0 328000.0 0.46 0.624 0.9994 2073029 Maybridge1_006839 O=C(CSCc1cccc2ccccc12)NNC(=S)Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O20 compound treatment 831086.0 257000.0 0.37 926091.0 336000.0 0.47 0.5892 0.9925 1028002 Maybridge1_006840 OCCCN1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O21 compound treatment 878296.0 304000.0 0.43 937283.0 347000.0 0.48 0.6477 0.9984 1259711 Maybridge1_006841 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3cncc(Br)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O22 compound treatment 841553.0 267000.0 0.38 912215.0 322000.0 0.45 0.5861 0.9966 1036029 Maybridge1_006842 OC(=O)CCC(=O)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O23 mock treatment 870073.0 296000.0 0.42 919407.0 329000.0 0.46 0.6218 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 O24 mock treatment 520892.0 -53300.0 -0.08 256120.0 -334000.0 -0.47 -0.3834 -0.8114 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P01 compound treatment 793973.0 220000.0 0.31 804095.0 214000.0 0.3 0.4316 0.9997 2073030 Maybridge1_006843 Cc1cc(C)c(C(=O)NCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P02 compound treatment 824079.0 250000.0 0.36 856164.0 266000.0 0.37 0.5132 0.9998 2073031 Maybridge1_006844 O=C(CC(=O)c1ccccn1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P03 compound treatment 811515.0 237000.0 0.34 844749.0 254000.0 0.35 0.4893 0.9997 1673412 Maybridge1_006845 Brc1ccc2OC(=O)C(Cc2c1)C(=O)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P04 compound treatment 839030.0 265000.0 0.38 868679.0 278000.0 0.39 0.5406 0.9999 1143576 Maybridge1_006846 Cc1ccc2cc(NC(=O)c3ccccc3)ccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P05 compound treatment 821387.0 247000.0 0.35 860244.0 270000.0 0.38 0.5145 0.9994 2073032 Maybridge1_006847 COc1ccc(cc1)S(=O)(=O)NNC(=O)c2ccc(cc2)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P06 compound treatment 832936.0 259000.0 0.37 864735.0 274000.0 0.38 0.5306 0.9998 1150448 Maybridge1_006848 CCc1ccc(cc1)C(=O)Nc2ccc3nc(C)ccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P07 compound treatment 852016.0 278000.0 0.4 893527.0 303000.0 0.42 0.5782 0.9994 2073033 Maybridge1_006849 COc1ccc(cc1OC)C(=O)NNC(=O)c2ccc(cc2)n3c(C)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P08 compound treatment 826845.0 253000.0 0.36 843796.0 253000.0 0.35 0.5038 1.0 2073034 Maybridge1_006850 CC(=O)OC[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P09 compound treatment 853040.0 279000.0 0.4 860972.0 270000.0 0.38 0.5471 0.9997 1405837 Maybridge1_006851 COc1ccc(Oc2ncccc2NS(=O)(=O)c3ccc(OC)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P10 compound treatment 829566.0 255000.0 0.36 851565.0 261000.0 0.36 0.5142 1.0 2073035 Maybridge1_006852 CC(=NNC(=N)NC(=S)Nc1ccccc1)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P11 compound treatment 828192.0 254000.0 0.36 832010.0 241000.0 0.34 0.4935 0.9994 1637974 Maybridge1_006853 Cc1ccc(C)n1c2ccc(cc2)C(=O)ON3C(=O)CCC3=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P12 compound treatment 817452.0 243000.0 0.35 857677.0 267000.0 0.37 0.5081 0.9993 2073036 Maybridge1_006854 CCCCCCCc1c(O)c2ccccc2[nH]c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P13 compound treatment 808566.0 234000.0 0.33 836225.0 246000.0 0.34 0.478 0.9999 2073037 Maybridge1_006855 Cc1cc(Oc2ccccc2)ccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P14 compound treatment 810929.0 237000.0 0.34 830607.0 240000.0 0.33 0.4748 1.0 1050525 Maybridge1_006856 CCCC(NC(=O)C(C)N)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P15 compound treatment 822865.0 249000.0 0.35 891966.0 301000.0 0.42 0.5473 0.9963 1044269 Maybridge1_006857 Cc1nc(O)c([N+](=O)[O-])c(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P16 compound treatment 819199.0 245000.0 0.35 843553.0 253000.0 0.35 0.4959 1.0 1926183 Maybridge1_006858 O=C1C(C(=O)c2ccccc12)c3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P17 compound treatment 827795.0 254000.0 0.36 888519.0 298000.0 0.42 0.5489 0.9975 2073038 Maybridge1_006859 Cc1cc(c(C#N)c(=O)[nH]1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P18 compound treatment 846979.0 273000.0 0.39 865154.0 275000.0 0.38 0.5451 1.0 1464027 Maybridge1_006860 OC(=O)c1cn(C2CCCCC2)c3ccccc3c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P19 compound treatment 831939.0 258000.0 0.37 879841.0 289000.0 0.4 0.5445 0.9988 2073039 Maybridge1_006861 O=C(CC#N)NNC(=S)NCC1CCCO1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P20 compound treatment 809474.0 235000.0 0.33 862758.0 272000.0 0.38 0.505 0.998 2073040 Maybridge1_006862 CC/1(C)C2CC[C@](C)(C2)\C1=N\OC(=O)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P21 compound treatment 829467.0 255000.0 0.36 867711.0 277000.0 0.39 0.53 0.9995 1165383 Maybridge1_006863 Cc1cc(N2CCN(CC2)c3nc4cc(Cl)ccc4s3)c5ccccc5n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P22 compound treatment 824205.0 250000.0 0.36 885602.0 295000.0 0.41 0.5424 0.9973 2073041 Maybridge1_006864 NNC(=O)[C@H]1C[C@H]1C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P23 mock treatment 791144.0 217000.0 0.31 839556.0 249000.0 0.35 0.4637 0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.560 P24 mock treatment 539512.0 -34700.0 -0.05 262522.0 -328000.0 -0.46 -0.3584 -0.7789 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A01 compound treatment 809903.0 215000.0 0.31 840198.0 220000.0 0.31 0.4338 1.0 2073042 Maybridge1_006865 Cc1cc(C)nc(SC(=O)OC(C)(C)C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A02 compound treatment 818428.0 224000.0 0.32 847038.0 227000.0 0.32 0.4491 1.0 2073043 Maybridge1_006866 Cc1nc(SCc2c(F)cccc2Cl)nc(O)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A03 compound treatment 836617.0 242000.0 0.34 872360.0 252000.0 0.35 0.4923 0.9999 1208677 Maybridge1_006867 OC(=O)CNC(=O)c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A04 compound treatment 865402.0 271000.0 0.39 891472.0 272000.0 0.38 0.5401 1.0 2073044 Maybridge1_006868 Clc1cc(Cl)cc(NC(=S)NCc2cccs2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A05 compound treatment 872448.0 278000.0 0.4 901838.0 282000.0 0.39 0.5574 1.0 2073045 Maybridge1_006869 CC(=O)c1c(C)n(O)c2ccc3nonc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A06 compound treatment 878520.0 284000.0 0.4 909063.0 289000.0 0.4 0.5707 1.0 2073046 Maybridge1_006870 COCc1cc(O)nc(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A07 compound treatment 891274.0 297000.0 0.42 939819.0 320000.0 0.45 0.6138 0.9996 1520977 Maybridge1_006871 CC(C)(C)c1ccc(cc1)C(=O)N2CCC(CC2)NC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A08 compound treatment 913691.0 319000.0 0.45 986401.0 366000.0 0.51 0.6823 0.9982 2073047 Maybridge1_006872 Cc1cc(Br)ccc1Nc2ncnc(N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A09 compound treatment 903747.0 309000.0 0.44 922455.0 303000.0 0.42 0.6092 0.9998 1307029 Maybridge1_006873 COc1ccccc1CC(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A10 compound treatment 903805.0 309000.0 0.44 930832.0 311000.0 0.43 0.6176 1.0 2073048 Maybridge1_006874 Clc1cccc(NC(=S)NNC(=O)C2CC2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A11 compound treatment 875993.0 281000.0 0.4 917904.0 298000.0 0.42 0.5768 0.9998 2073049 Maybridge1_006875 COc1ccc(CCNS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A12 compound treatment 880981.0 286000.0 0.41 938075.0 318000.0 0.44 0.6018 0.9991 2073050 Maybridge1_006876 COCc1cc(O)nc(NC(=N)Nc2ccc(Cl)c(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A13 compound treatment 906409.0 312000.0 0.44 934933.0 315000.0 0.44 0.6242 1.0 1130829 Maybridge1_006877 Clc1cccc(c1Cl)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A14 compound treatment 935196.0 341000.0 0.48 934670.0 315000.0 0.44 0.6529 0.9988 1698799 Maybridge1_006878 OC(=O)CCNC(=S)Nc1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A15 compound treatment 930930.0 336000.0 0.48 965134.0 345000.0 0.48 0.6787 1.0 1523035 Maybridge1_006879 CC1(C)C2CCC1(C)C(C2)(Nc3ccccc3)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A16 compound treatment 945746.0 351000.0 0.5 962892.0 343000.0 0.48 0.6914 0.9998 1525521 Maybridge1_006880 Cc1nc(N)nc(O)c1Cc2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A17 compound treatment 923690.0 329000.0 0.47 968990.0 349000.0 0.49 0.6752 0.9998 2073051 Maybridge1_006881 C/C(=C\c1ccccc1[N+](=O)[O-])/c2cc3ccccc3c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A18 compound treatment 909037.0 314000.0 0.45 939847.0 320000.0 0.45 0.6317 1.0 2073052 Maybridge1_006882 CSc1nc(C)c(CC(=C)C)c(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A19 compound treatment 884297.0 290000.0 0.41 975371.0 355000.0 0.5 0.6419 0.9958 2073053 Maybridge1_006883 N#CCc1nc(cs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A20 compound treatment 866714.0 272000.0 0.39 943833.0 324000.0 0.45 0.5931 0.997 2073054 Maybridge1_006884 CSC(=N)NC(=S)Nc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A21 compound treatment 1054817.0 460000.0 0.65 1101463.0 482000.0 0.67 0.9377 0.9999 1067983 Maybridge1_006885 Oc1ccc2c(cc(=O)oc2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A22 compound treatment 836139.0 242000.0 0.34 895791.0 276000.0 0.38 0.515 0.9984 2073055 Maybridge1_006886 CC(C)(C)/N=C(\NN)/NCC1CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A23 mock treatment 844823.0 250000.0 0.36 883276.0 263000.0 0.37 0.5114 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 A24 mock treatment 132067.0 -463000.0 -0.66 146683.0 -473000.0 -0.66 -0.9318 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B01 compound treatment 839176.0 245000.0 0.35 836493.0 217000.0 0.3 0.4595 0.9975 2073056 Maybridge1_006887 CC(C)(C)C(=O)Cn1nnc(n1)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B02 compound treatment 828271.0 234000.0 0.33 848407.0 228000.0 0.32 0.4603 0.9998 1076487 Maybridge1_006888 COc1ccc(CCN2CSC(=S)N(CCc3ccc(OC)c(OC)c3)C2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B03 compound treatment 925629.0 331000.0 0.47 925106.0 305000.0 0.43 0.6339 0.9987 2073057 Maybridge1_006889 NNC(=O)Cn1nnc(n1)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B04 compound treatment 921161.0 327000.0 0.46 955952.0 336000.0 0.47 0.6598 1.0 1080223 Maybridge1_006890 CCOC(=O)c1ccc(NC(=S)NC(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B05 compound treatment 944498.0 350000.0 0.5 961292.0 341000.0 0.48 0.6885 0.9998 1668302 Maybridge1_006891 CCCc1cc(=O)oc2cc(OCC(=O)NN)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B06 compound treatment 900090.0 306000.0 0.43 886790.0 267000.0 0.37 0.5704 0.997 2073058 Maybridge1_006892 Cc1cc(C)c(NC(=O)CC2SC(=N)NC2=O)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B07 compound treatment 987460.0 393000.0 0.56 976574.0 357000.0 0.5 0.7468 0.9983 1364298 Maybridge1_006893 COCc1cc(=O)oc2cc(O)c(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B08 compound treatment 965269.0 371000.0 0.53 936828.0 317000.0 0.44 0.6853 0.9962 2073059 Maybridge1_006894 CCO/C=C/1\SC(=S)N(CCc2ccccc2)C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B09 compound treatment 960327.0 366000.0 0.52 981279.0 361000.0 0.5 0.7242 0.9999 2073060 Maybridge1_006895 NNC(=S)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B10 compound treatment 978654.0 384000.0 0.55 982477.0 363000.0 0.51 0.7438 0.9993 2073061 Maybridge1_006896 [O-][N+](=O)/C=C/c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B11 compound treatment 971749.0 377000.0 0.54 1001543.0 382000.0 0.53 0.7556 1.0 2073062 Maybridge1_006897 Sc1nc2ccccc2[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B12 compound treatment 948468.0 354000.0 0.5 947696.0 328000.0 0.46 0.6791 0.9988 1275541 Maybridge1_006898 CC(N1CSC(=S)N(C1)C(C)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B13 compound treatment 969018.0 374000.0 0.53 996078.0 376000.0 0.52 0.7475 1.0 2073063 Maybridge1_006899 Cc1cccc(Cl)c1NC(=S)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B14 compound treatment 947149.0 353000.0 0.5 978118.0 358000.0 0.5 0.7078 1.0 2073064 Maybridge1_006900 Clc1ccc(/N=C\2/NCCS2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B15 compound treatment 1017148.0 423000.0 0.6 935702.0 316000.0 0.44 0.7363 0.9883 2073065 Maybridge1_006901 N/C(=N\O)/Cc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B16 compound treatment 982517.0 388000.0 0.55 989180.0 369000.0 0.51 0.7543 0.9994 1683503 Maybridge1_006902 CCc1ccccc1Nc2nnc(S)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B17 compound treatment 986633.0 392000.0 0.56 1037531.0 418000.0 0.58 0.8061 0.9998 2073066 Maybridge1_006903 Cc1ccc(/C=C/[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B18 compound treatment 970089.0 376000.0 0.53 945839.0 326000.0 0.45 0.699 0.9968 1671035 Maybridge1_006904 Cc1cccc(NCN2C(=O)c3ccccc3C2=O)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B19 compound treatment 6281087.0 5690000.0 8.09 6413759.0 5790000.0 8.08 11.4321 1.0 2073067 Maybridge1_006905 CCN(CC)c1ccc(/C=C/2\N=C(OC2=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B20 compound treatment 1010559.0 416000.0 0.59 1058259.0 438000.0 0.61 0.8506 0.9999 2073068 Maybridge1_006906 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(Cl)cn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B21 compound treatment 934380.0 340000.0 0.48 967358.0 347000.0 0.48 0.6843 1.0 1074249 Maybridge1_006907 CC1CCN(CC1)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B22 compound treatment 910374.0 316000.0 0.45 944350.0 324000.0 0.45 0.6375 1.0 2073069 Maybridge1_006908 [O-][N+](=O)/C=C/c1ccccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B23 mock treatment 947864.0 353000.0 0.5 967475.0 348000.0 0.48 0.698 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 B24 mock treatment 134341.0 -460000.0 -0.65 175633.0 -444000.0 -0.62 -0.901 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C01 compound treatment 766153.0 172000.0 0.24 783269.0 163000.0 0.23 0.3336 0.9994 1464302 Maybridge1_006909 CC(NCc1ccccc1)C2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C02 compound treatment 768098.0 174000.0 0.25 838943.0 219000.0 0.31 0.3905 0.9944 2073070 Maybridge1_006910 C1CCN(CC1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C03 compound treatment 824952.0 230000.0 0.33 894163.0 274000.0 0.38 0.5021 0.997 2073071 Maybridge1_006911 CC(C)(C)c1cc([N+](=O)[O-])c2cc(cc([N+](=O)[O-])c2c1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C04 compound treatment 819546.0 225000.0 0.32 846629.0 227000.0 0.32 0.4498 1.0 1313220 Maybridge1_006912 Cc1cc(Nc2ccc(F)c(Cl)c2)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C05 compound treatment 870449.0 276000.0 0.39 899662.0 280000.0 0.39 0.5533 1.0 1497623 Maybridge1_006913 CCOC(=O)c1c(C)n(OC)c2ccc3nonc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C06 compound treatment 823433.0 229000.0 0.33 891573.0 272000.0 0.38 0.498 0.9971 2073072 Maybridge1_006914 COCc1cc(O)nc(SC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C07 compound treatment 860659.0 266000.0 0.38 888871.0 269000.0 0.38 0.5328 1.0 1260724 Maybridge1_006915 Clc1ccc(cc1)C(=O)N2CCC(CC2)NC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C08 compound treatment 874604.0 280000.0 0.4 919181.0 299000.0 0.42 0.5767 0.9997 1030238 Maybridge1_006916 NC(=N)NC(=N)Nc1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C09 compound treatment 891233.0 297000.0 0.42 950776.0 331000.0 0.46 0.6246 0.999 1394196 Maybridge1_006917 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C10 compound treatment 867509.0 273000.0 0.39 825962.0 206000.0 0.29 0.4776 0.9891 1117027 Maybridge1_006918 NC(=N)NC(=N)Nc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C11 compound treatment 887743.0 293000.0 0.42 914478.0 295000.0 0.41 0.5853 1.0 1778921 Maybridge1_006919 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C12 compound treatment 845910.0 251000.0 0.36 897746.0 278000.0 0.39 0.5267 0.9992 2073073 Maybridge1_006920 NC(=N)NC(=N)Nc1ccccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C13 compound treatment 891612.0 297000.0 0.42 962998.0 343000.0 0.48 0.637 0.9981 1216085 Maybridge1_006921 O=C(Cc1ccccc1)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C14 compound treatment 913640.0 319000.0 0.45 940798.0 321000.0 0.45 0.6373 1.0 1324187 Maybridge1_006922 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C15 compound treatment 909663.0 315000.0 0.45 909329.0 289000.0 0.4 0.6022 0.9986 2073074 Maybridge1_006923 COC(=O)C1C(=O)CC(=O)CC1(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C16 compound treatment 894628.0 300000.0 0.43 870284.0 250000.0 0.35 0.5486 0.995 2073075 Maybridge1_006924 NC(=N)NC(=N)Nc1ccc2OCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C17 compound treatment 930724.0 336000.0 0.48 899863.0 280000.0 0.39 0.6141 0.995 2073076 Maybridge1_006925 CC(=O)[C@@H]1[C@H]([C@H](C(=O)C)[C@](C)(O)CC1=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C18 compound treatment 1062790.0 468000.0 0.67 880234.0 260000.0 0.36 0.7275 0.9593 1617897 Maybridge1_006926 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C19 compound treatment 918454.0 324000.0 0.46 905296.0 285000.0 0.4 0.6071 0.9974 1006315 Maybridge1_006927 OC(=O)C(c1ccccc1)(c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C20 compound treatment 853794.0 259000.0 0.37 912716.0 293000.0 0.41 0.5494 0.9987 2073077 Maybridge1_006928 FC(F)(F)c1ccccc1c2nnn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C21 compound treatment 862703.0 268000.0 0.38 911845.0 292000.0 0.41 0.5575 0.9995 2073078 Maybridge1_006929 NC(=N)NC(=N)Nc1ccc(F)cc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C22 compound treatment 851077.0 257000.0 0.36 900249.0 280000.0 0.39 0.5344 0.9994 2073079 Maybridge1_006930 S=C(NCC1CC1)NCC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C23 mock treatment 855359.0 261000.0 0.37 904948.0 285000.0 0.4 0.5433 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 C24 mock treatment 138113.0 -456000.0 -0.65 169378.0 -451000.0 -0.63 -0.9033 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D01 compound treatment 867790.0 273000.0 0.39 853514.0 234000.0 0.33 0.5051 0.9962 1361400 Maybridge1_006931 Nc1ncnc(Nc2cccc(C#N)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D02 compound treatment 874667.0 280000.0 0.4 877243.0 257000.0 0.36 0.5354 0.9986 1076055 Maybridge1_006932 CCOc1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D03 compound treatment 939875.0 345000.0 0.49 910486.0 291000.0 0.41 0.6338 0.9954 2073080 Maybridge1_006933 CCCc1cc(O)nc(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D04 compound treatment 967077.0 373000.0 0.53 984572.0 365000.0 0.51 0.7342 0.9998 2073081 Maybridge1_006934 COc1ccc(CCN2C(=O)/C(=C/c3c(F)c(F)c(F)c(F)c3F)/SC2=S)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D05 compound treatment 955186.0 361000.0 0.51 991750.0 372000.0 0.52 0.7293 1.0 2073082 Maybridge1_006935 CCCc1cc(O)nc(NC(=N)Nc2cc(Cl)cc(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D06 compound treatment 909046.0 314000.0 0.45 944747.0 325000.0 0.45 0.6366 1.0 1351539 Maybridge1_006936 O=C1Nc2ccccc2C1(C3C(=O)NC(=O)NC3=O)C4C(=O)NC(=O)NC4=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D07 compound treatment 970723.0 376000.0 0.53 986189.0 366000.0 0.51 0.7394 0.9997 2073083 Maybridge1_006937 Clc1cccc(c2nnn[nH]2)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D08 compound treatment 936646.0 342000.0 0.49 948440.0 329000.0 0.46 0.668 0.9996 2073084 Maybridge1_006938 Clc1cccc(Cl)c1NC(=S)NC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D09 compound treatment 1006743.0 412000.0 0.59 994796.0 375000.0 0.52 0.7842 0.9984 1603314 Maybridge1_006939 Fc1ccc(NC(=S)NC2CCCCCCCCCCC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D10 compound treatment 980253.0 386000.0 0.55 982357.0 362000.0 0.51 0.7453 0.9992 1023877 Maybridge1_006940 CC(C)C(NS(=O)(=O)c1ccc(C)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D11 compound treatment 1000775.0 406000.0 0.58 1042886.0 423000.0 0.59 0.8256 0.9999 2073085 Maybridge1_006941 Fc1ccccc1Nc2nnc(S)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D12 compound treatment 964345.0 370000.0 0.53 956947.0 337000.0 0.47 0.7042 0.9984 2073086 Maybridge1_006942 NNC(=S)NCCCN1CCOCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D13 compound treatment 1008099.0 414000.0 0.59 997478.0 378000.0 0.53 0.7882 0.9985 1065962 Maybridge1_006943 NNC(=S)Nc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D14 compound treatment 967164.0 373000.0 0.53 974180.0 354000.0 0.49 0.724 0.9994 2073087 Maybridge1_006944 Clc1cccc(NC2=NCCS2)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D15 compound treatment 1048639.0 454000.0 0.65 1037910.0 418000.0 0.58 0.8688 0.9987 1014454 Maybridge1_006945 O=c1oc(nc2ccccc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D16 compound treatment 999242.0 405000.0 0.58 977791.0 358000.0 0.5 0.7598 0.9975 2073088 Maybridge1_006946 CCOc1ccc(/C=C(\C)/[N+](=O)[O-])cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D17 compound treatment 1060420.0 466000.0 0.66 1014572.0 395000.0 0.55 0.8576 0.9958 1037879 Maybridge1_006947 NC(=N)SCc1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D18 compound treatment 964267.0 370000.0 0.53 975282.0 355000.0 0.5 0.7222 0.9996 2073089 Maybridge1_006948 CSc1cccc(NC(=S)NCc2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D19 compound treatment 977286.0 383000.0 0.54 1019133.0 399000.0 0.56 0.7785 0.9999 2073090 Maybridge1_006949 CCN(CC)c1ccc(/C=N/N=C/c2ccc(cc2)N(CC)CC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D20 compound treatment 956663.0 362000.0 0.51 1017845.0 398000.0 0.55 0.7565 0.9993 2073091 Maybridge1_006950 Oc1ccccc1/C=N/c2ccc(Cl)cn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D21 compound treatment 982267.0 388000.0 0.55 1003688.0 384000.0 0.54 0.7683 0.9999 1039360 Maybridge1_006951 CN(C)C(=S)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D22 compound treatment 945395.0 351000.0 0.5 1002063.0 382000.0 0.53 0.7296 0.9995 2073092 Maybridge1_006952 CC(=O)Nc1ccc(cc1)C2=N/C(=C\c3cccs3)/C(=O)O2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D23 mock treatment 989170.0 395000.0 0.56 1014475.0 395000.0 0.55 0.7859 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 D24 mock treatment 156092.0 -438000.0 -0.62 157601.0 -462000.0 -0.64 -0.8969 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E01 compound treatment 856072.0 261000.0 0.37 847127.0 227000.0 0.32 0.487 0.9968 1005170 Maybridge1_006953 OC(=O)C(c1ccc(Cl)cc1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E02 compound treatment 845710.0 251000.0 0.36 906947.0 287000.0 0.4 0.5356 0.9984 1402665 Maybridge1_006954 Clc1ccc(cc1)C(=O)Cn2nnc(n2)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E03 compound treatment 934354.0 340000.0 0.48 974534.0 355000.0 0.49 0.6914 0.9999 1077391 Maybridge1_006955 COc1cc(CC#N)c(OC)cc1CC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E04 compound treatment 915364.0 321000.0 0.46 967252.0 347000.0 0.48 0.6651 0.9996 1322296 Maybridge1_006956 Cc1cc(Nc2ccc(F)cc2F)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E05 compound treatment 889829.0 295000.0 0.42 878024.0 258000.0 0.36 0.5514 0.9971 2073093 Maybridge1_006957 CCCCCCCCCCCCC/1CCCC\C1=N\O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E06 compound treatment 923947.0 329000.0 0.47 963449.0 344000.0 0.48 0.67 0.9999 1256576 Maybridge1_006958 Cc1cc(C)c(N=c2oc(cs2)C(C)(C)C)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E07 compound treatment 979041.0 384000.0 0.55 962825.0 343000.0 0.48 0.7248 0.9978 1456979 Maybridge1_006959 Brc1ccccc1C(=O)N2CCC(CC2)NC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E08 compound treatment 947352.0 353000.0 0.5 986129.0 366000.0 0.51 0.7159 1.0 2073094 Maybridge1_006960 NC(=N)NC(=N)Nc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E09 compound treatment 987167.0 393000.0 0.56 1006114.0 386000.0 0.54 0.7756 0.9998 1736885 Maybridge1_006961 Clc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E10 compound treatment 965038.0 370000.0 0.53 987734.0 368000.0 0.51 0.7353 0.9999 2073095 Maybridge1_006962 NC(=N)NC(=N)Nc1ccc(I)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E11 compound treatment 996767.0 402000.0 0.57 1019412.0 399000.0 0.56 0.7984 0.9999 1670579 Maybridge1_006963 Clc1ccc(cc1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E12 compound treatment 931011.0 336000.0 0.48 999708.0 380000.0 0.53 0.7128 0.9987 2073096 Maybridge1_006964 COCc1cc(O)nc(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E13 compound treatment 951450.0 357000.0 0.51 1020288.0 400000.0 0.56 0.7537 0.9989 2073097 Maybridge1_006965 CC(C)(C)NS(=O)(=O)NC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E14 compound treatment 950823.0 356000.0 0.51 990529.0 371000.0 0.52 0.7237 0.9999 2073098 Maybridge1_006966 OC(=O)CCNC(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E15 compound treatment 955347.0 361000.0 0.51 996674.0 377000.0 0.53 0.7343 0.9999 2073099 Maybridge1_006967 S(c1c(nc2sccn12)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E16 compound treatment 957982.0 363000.0 0.52 994090.0 374000.0 0.52 0.7344 1.0 2073100 Maybridge1_006968 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E17 compound treatment 1024148.0 430000.0 0.61 1036127.0 416000.0 0.58 0.8424 0.9997 2073101 Maybridge1_006969 O=C1c2ccccc2-c3ccc4ccccc4c13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E18 compound treatment 966100.0 372000.0 0.53 1007563.0 388000.0 0.54 0.7559 0.9999 2073102 Maybridge1_006970 Cc1cc(NC(=N)NC(=N)N)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E19 compound treatment 948580.0 354000.0 0.5 1031382.0 411000.0 0.57 0.7618 0.9979 2073103 Maybridge1_006971 CC(=O)OC[C@H](OC(=O)C)[C@H](OC(=O)C)[C@@H](CNC(=O)c1ccc(C)c(C)c1)OC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E20 compound treatment 954063.0 359000.0 0.51 1003375.0 383000.0 0.53 0.7396 0.9997 2073104 Maybridge1_006972 CCOC(=N)c1ccc(C)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E21 compound treatment 962940.0 368000.0 0.52 1040291.0 420000.0 0.59 0.785 0.9984 2073105 Maybridge1_006973 NC(=N)NC(=N)Nc1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E22 compound treatment 937674.0 343000.0 0.49 1021580.0 402000.0 0.56 0.7411 0.9976 2073106 Maybridge1_006974 Fc1ccc(NC(=S)NCCNC(=S)Nc2ccc(F)cc2F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E23 mock treatment 972651.0 378000.0 0.54 993178.0 373000.0 0.52 0.7483 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 E24 mock treatment 164139.0 -430000.0 -0.61 161478.0 -458000.0 -0.64 -0.885 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F01 compound treatment 872953.0 278000.0 0.4 837880.0 218000.0 0.3 0.4949 0.9915 1107832 Maybridge1_006975 CC1(C)CC2(C)OC(=O)c3ccccc3N2C(=S)N1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F02 compound treatment 897421.0 303000.0 0.43 875866.0 256000.0 0.36 0.5569 0.9956 1921381 Maybridge1_006976 CCOc1ccc(/C=C/[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F03 compound treatment 976674.0 382000.0 0.54 997096.0 377000.0 0.53 0.7562 0.9999 1536659 Maybridge1_006977 CCCc1cc(=O)oc2cc(O)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F04 compound treatment 965686.0 371000.0 0.53 927881.0 308000.0 0.43 0.6769 0.9948 2073107 Maybridge1_006978 Nc1ccccc1SC(CC(=O)c2ccccc2)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F05 compound treatment 982788.0 388000.0 0.55 1023477.0 404000.0 0.56 0.7884 1.0 1061990 Maybridge1_006979 Nc1nc(N)nc(n1)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F06 compound treatment 991597.0 397000.0 0.56 954904.0 335000.0 0.47 0.7296 0.9956 1497584 Maybridge1_006980 CC(C)c1ccc(cc1)N2CSC(=S)N(C2)c3ccc(cc3)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F07 compound treatment 1045824.0 451000.0 0.64 1007762.0 388000.0 0.54 0.8362 0.9964 2073108 Maybridge1_006981 Nc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F08 compound treatment 995884.0 401000.0 0.57 978296.0 358000.0 0.5 0.757 0.9978 2073109 Maybridge1_006982 Cc1cc(C)c(NC(=S)N)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F09 compound treatment 1002885.0 408000.0 0.58 1008933.0 389000.0 0.54 0.7942 0.9994 2073110 Maybridge1_006983 COc1cc(/C=N/C2CCCCCCCCCCC2)ccc1OCc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F10 compound treatment 1008311.0 414000.0 0.59 944342.0 324000.0 0.45 0.736 0.9916 1211869 Maybridge1_006984 Cc1cc(NC(=O)CCC(=O)O)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F11 compound treatment 1006314.0 412000.0 0.59 1001886.0 382000.0 0.53 0.7907 0.9989 2073111 Maybridge1_006985 COc1ccccc1Nc2nnc(S)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F12 compound treatment 948600.0 354000.0 0.5 973326.0 353000.0 0.49 0.7045 0.9999 2073112 Maybridge1_006986 C/C(=C\c1ccccc1Cl)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F13 compound treatment 996756.0 402000.0 0.57 943917.0 324000.0 0.45 0.7239 0.9932 1119197 Maybridge1_006987 Cc1ccc(Cl)cc1NC(=S)NCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F14 compound treatment 962403.0 368000.0 0.52 973414.0 353000.0 0.49 0.7185 0.9996 2073113 Maybridge1_006988 COc1ccc(CC/N=C/c2cc(Br)ccc2O)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F15 compound treatment 1042514.0 448000.0 0.64 1010284.0 390000.0 0.54 0.8354 0.9969 2073114 Maybridge1_006989 O=C/1OC(=N\C1=C/c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F16 compound treatment 998127.0 404000.0 0.57 1010684.0 391000.0 0.54 0.7912 0.9997 2073115 Maybridge1_006990 C/C(=C\c1cccc(c1)[N+](=O)[O-])/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F17 compound treatment 1055783.0 461000.0 0.66 1041660.0 422000.0 0.59 0.8797 0.9985 1018868 Maybridge1_006991 NC(=N)SCc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F18 compound treatment 1013464.0 419000.0 0.6 987642.0 368000.0 0.51 0.7839 0.9972 2073116 Maybridge1_006992 Cc1cc(C)cc(/N=C/c2cc(Br)ccc2O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F19 compound treatment 1008320.0 414000.0 0.59 1074582.0 455000.0 0.63 0.8644 0.9993 2073117 Maybridge1_006993 NC(=N)SCc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F20 compound treatment 1014475.0 420000.0 0.6 1027264.0 407000.0 0.57 0.824 0.9997 2073118 Maybridge1_006994 Oc1ccccc1/C=N/c2ccccc2SCCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F21 compound treatment 1027494.0 433000.0 0.62 1086909.0 467000.0 0.65 0.8959 0.9996 1071877 Maybridge1_006995 COc1ccc(NC(=S)Nc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F22 compound treatment 955632.0 361000.0 0.51 992280.0 372000.0 0.52 0.7303 1.0 1111249 Maybridge1_006996 O=C1N(Nc2ccccc2)C(=O)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F23 mock treatment 1011330.0 417000.0 0.59 1035506.0 416000.0 0.58 0.8289 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 F24 mock treatment 158083.0 -436000.0 -0.62 164589.0 -455000.0 -0.64 -0.888 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G01 compound treatment 839863.0 245000.0 0.35 825551.0 206000.0 0.29 0.4494 0.9953 1219183 Maybridge1_006997 O=c1c(C#N)c2[nH]c3ccccc3n2c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G02 compound treatment 864534.0 270000.0 0.38 847387.0 227000.0 0.32 0.4958 0.9955 1370310 Maybridge1_006998 CCOC(=O)Cn1nnc(n1)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G03 compound treatment 899268.0 305000.0 0.43 943630.0 324000.0 0.45 0.6256 0.9998 1983575 Maybridge1_006999 Nc1oc(c(c1C#N)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G04 compound treatment 890674.0 296000.0 0.42 890075.0 270000.0 0.38 0.5642 0.9985 1449956 Maybridge1_007000 Cc1cc(O)nc(NC(=O)C2CC2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G05 compound treatment 923990.0 329000.0 0.47 940496.0 321000.0 0.45 0.6474 0.9997 2073119 Maybridge1_007001 CCCCCCCCCCCCCCCCC/1CCCC\C1=N\O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G06 compound treatment 860098.0 266000.0 0.38 851895.0 232000.0 0.32 0.4958 0.997 2073120 Maybridge1_007002 NC(=N)NC(=N)Nc1c(F)cccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G07 compound treatment 867112.0 273000.0 0.39 903390.0 283000.0 0.4 0.5536 1.0 1337485 Maybridge1_007003 COc1ccccc1C2CCN(CC2)C(=O)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G08 compound treatment 900929.0 306000.0 0.44 952889.0 333000.0 0.46 0.6364 0.9995 1013598 Maybridge1_007004 NC(=N)NC(=N)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G09 compound treatment 930958.0 336000.0 0.48 961090.0 341000.0 0.48 0.6747 1.0 1439324 Maybridge1_007005 CCOC(=O)c1ccc(NC(=O)CCCN2CCN(Cc3ccccc3)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G10 compound treatment 874852.0 280000.0 0.4 941716.0 322000.0 0.45 0.5992 0.9982 2073121 Maybridge1_007006 Cc1ccc(NC(=N)NC(=N)N)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G11 compound treatment 885317.0 291000.0 0.41 992649.0 373000.0 0.52 0.6599 0.9936 1390951 Maybridge1_007007 Cc1ccc(cc1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G12 compound treatment 927425.0 333000.0 0.47 955753.0 336000.0 0.47 0.6659 1.0 2073122 Maybridge1_007008 NC(=N)NC(=N)Nc1cccc(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G13 compound treatment 896887.0 302000.0 0.43 974898.0 355000.0 0.5 0.6541 0.9975 2073123 Maybridge1_007009 CC1(O)CCCCCCCCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G14 compound treatment 920625.0 326000.0 0.46 990388.0 370000.0 0.52 0.6932 0.9985 1600021 Maybridge1_007010 CC(C)(C)c1ccc(NC(=S)NCCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G15 compound treatment 912113.0 318000.0 0.45 1006367.0 386000.0 0.54 0.7004 0.9961 2073124 Maybridge1_007011 NC(=O)c1c(cccc1C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G16 compound treatment 937202.0 343000.0 0.49 960412.0 340000.0 0.47 0.6803 0.9999 1700634 Maybridge1_007012 Clc1cc(Cl)cc(Nc2ncnc(n2)n3cccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G17 compound treatment 1006575.0 412000.0 0.59 990479.0 371000.0 0.52 0.7797 0.998 2073125 Maybridge1_007013 Cc1ccc(Oc2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G18 compound treatment 910993.0 316000.0 0.45 946174.0 326000.0 0.46 0.6399 1.0 2073126 Maybridge1_007014 COc1ccccc1N/2C(=O)CS\C2=N/N=C/c3ccccc3O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G19 compound treatment 970596.0 376000.0 0.53 1012528.0 393000.0 0.55 0.7653 0.9999 2073127 Maybridge1_007015 CCOc1c(C)nc(C)c(OCC)c1c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G20 compound treatment 928192.0 334000.0 0.47 918008.0 298000.0 0.42 0.6294 0.9978 2073128 Maybridge1_007016 Cc1ccc(cc1Cl)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G21 compound treatment 938869.0 344000.0 0.49 992280.0 372000.0 0.52 0.7134 0.9996 1103787 Maybridge1_007017 Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G22 compound treatment 909596.0 315000.0 0.45 982857.0 363000.0 0.51 0.6747 0.9981 2073129 Maybridge1_007018 Clc1cccc(NC(=S)NCCNC(=S)Nc2cccc(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G23 mock treatment 917556.0 323000.0 0.46 956302.0 336000.0 0.47 0.6565 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 G24 mock treatment 153567.0 -441000.0 -0.63 152582.0 -467000.0 -0.65 -0.9044 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H01 compound treatment 845740.0 251000.0 0.36 824903.0 205000.0 0.29 0.4547 0.9939 1037188 Maybridge1_007019 CCc1cc(O)nc(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H02 compound treatment 882453.0 288000.0 0.41 819797.0 200000.0 0.28 0.4866 0.9825 1080220 Maybridge1_007020 CCc1cccc(CC)c1N2C(=O)C=CC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H03 compound treatment 932233.0 338000.0 0.48 912301.0 292000.0 0.41 0.6279 0.9967 2073130 Maybridge1_007021 CCCC1=NNC(=O)C1Cc2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H04 compound treatment 927363.0 333000.0 0.47 918917.0 299000.0 0.42 0.6295 0.998 2073131 Maybridge1_007022 Clc1ccc(N2C(=O)C=CC2=O)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H05 compound treatment 957831.0 363000.0 0.52 946470.0 327000.0 0.46 0.6873 0.998 1486875 Maybridge1_007023 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H06 compound treatment 926154.0 332000.0 0.47 947399.0 327000.0 0.46 0.6564 0.9999 2073132 Maybridge1_007024 CC(C)c1ccc(NC(=O)/C=C/C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H07 compound treatment 949849.0 355000.0 0.51 1006869.0 387000.0 0.54 0.7389 0.9995 2073133 Maybridge1_007025 Nc1ccc(cc1)S(=O)(=O)Nc2cc(F)ccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H08 compound treatment 961234.0 367000.0 0.52 946267.0 326000.0 0.46 0.6905 0.9977 1250169 Maybridge1_007026 COc1ccc(CCn2c(=O)c3cc4c(=O)n(CCc5ccc(OC)c(OC)c5)c(=O)c4cc3c2=O)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H09 compound treatment 992423.0 398000.0 0.57 994775.0 375000.0 0.52 0.7697 0.9992 1033953 Maybridge1_007027 O=C(CN1C(=O)c2ccccc2C1=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H10 compound treatment 949252.0 355000.0 0.5 963334.0 343000.0 0.48 0.6953 0.9997 2073134 Maybridge1_007028 Clc1cc(NC(=S)NC(=O)c2ccccc2)ccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H11 compound treatment 972728.0 378000.0 0.54 994447.0 375000.0 0.52 0.7496 0.9999 1006142 Maybridge1_007029 NC(=O)c1ccccc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H12 compound treatment 920310.0 326000.0 0.46 962681.0 343000.0 0.48 0.6656 0.9999 2073135 Maybridge1_007030 C/C(=C/c1cccc2ccccc12)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H13 compound treatment 992658.0 398000.0 0.57 959926.0 340000.0 0.47 0.7356 0.9961 1594746 Maybridge1_007031 OCCNC(=S)NCc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H14 compound treatment 984400.0 390000.0 0.55 987016.0 367000.0 0.51 0.754 0.9992 2073136 Maybridge1_007032 Sc1nc2cc(Cl)ccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H15 compound treatment 1002407.0 408000.0 0.58 1032385.0 412000.0 0.58 0.8169 1.0 1113880 Maybridge1_007033 CCOc1ccc(NCN2C(=O)c3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H16 compound treatment 984490.0 390000.0 0.55 992607.0 373000.0 0.52 0.7596 0.9995 2073137 Maybridge1_007034 C/C(=C\c1ccccc1[N+](=O)[O-])/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H17 compound treatment 1017425.0 423000.0 0.6 984490.0 365000.0 0.51 0.7847 0.9965 1166307 Maybridge1_007035 Cc1ccc(NC(=S)NCCO)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H18 compound treatment 953358.0 359000.0 0.51 942259.0 322000.0 0.45 0.6787 0.998 1606002 Maybridge1_007036 O=C1N(CNc2ccc(cc2)N3CCOCC3)C(=O)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H19 compound treatment 1006575.0 412000.0 0.59 1024660.0 405000.0 0.56 0.8134 0.9998 1653424 Maybridge1_007037 O=C1N(CNc2ccc(Oc3ccccc3)cc2)C(=O)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H20 compound treatment 914851.0 320000.0 0.46 1008270.0 388000.0 0.54 0.705 0.9963 2073138 Maybridge1_007038 Cc1cc(Br)ccc1NC(=S)Nc2ccc3ccccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H21 compound treatment 980691.0 386000.0 0.55 1049939.0 430000.0 0.6 0.8123 0.999 2073139 Maybridge1_007039 COc1ccc(Br)cc1/C=C/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H22 compound treatment 950700.0 356000.0 0.51 1002959.0 383000.0 0.53 0.7359 0.9996 2073140 Maybridge1_007040 Cn1nc(O)c2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H23 mock treatment 966709.0 372000.0 0.53 985515.0 366000.0 0.51 0.7347 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 H24 mock treatment 139538.0 -455000.0 -0.65 155579.0 -464000.0 -0.65 -0.9155 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I01 compound treatment 817168.0 223000.0 0.32 805598.0 186000.0 0.26 0.4069 0.995 1774525 Maybridge1_007041 OC(CNCc1ccccc1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I02 compound treatment 866326.0 272000.0 0.39 867368.0 247000.0 0.35 0.5173 0.9984 1332598 Maybridge1_007042 O=C(Cn1nnc(n1)N2CCCCC2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I03 compound treatment 881760.0 287000.0 0.41 918349.0 298000.0 0.42 0.5831 1.0 2073141 Maybridge1_007043 OC(=O)c1ccc(o1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I04 compound treatment 915840.0 321000.0 0.46 868258.0 248000.0 0.35 0.568 0.9907 2073142 Maybridge1_007044 Cc1nc(SCC(=O)C(C)(C)C)nc(O)c1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I05 compound treatment 942212.0 348000.0 0.49 943197.0 323000.0 0.45 0.6684 0.9989 1277061 Maybridge1_007045 COC(=O)c1ccccc1Sc2c(nc3ccccn23)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I06 compound treatment 962767.0 368000.0 0.52 927951.0 308000.0 0.43 0.674 0.9952 2073143 Maybridge1_007046 CSc1ccccc1NC(=N)NC(=N)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I07 compound treatment 969748.0 375000.0 0.53 944877.0 325000.0 0.45 0.6977 0.9967 1211026 Maybridge1_007047 O=C(NC1CCN(Cc2ccccc2)CC1)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I08 compound treatment 926597.0 332000.0 0.47 970333.0 350000.0 0.49 0.6794 0.9999 2073144 Maybridge1_007048 NC(=N)NC(=N)Nc1nc(cs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I09 compound treatment 834794.0 240000.0 0.34 916205.0 296000.0 0.41 0.5337 0.9955 1402258 Maybridge1_007049 COc1ccc(CCNC(=O)c2ccccc2Br)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I10 compound treatment 931451.0 337000.0 0.48 964460.0 345000.0 0.48 0.6785 1.0 1202989 Maybridge1_007050 Nc1ncnc(Nc2ccc(Cl)c(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I11 compound treatment 897362.0 303000.0 0.43 959438.0 340000.0 0.47 0.6393 0.9989 2073145 Maybridge1_007051 FC(F)(F)c1cc(cc(c1)S(=O)(=O)N2CCN(Cc3ccccc3)CC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I12 compound treatment 886782.0 292000.0 0.42 914471.0 295000.0 0.41 0.5843 1.0 2073146 Maybridge1_007052 NC(=N)NC(=N)Nc1ccc(Cl)cc1C(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I13 compound treatment 957336.0 363000.0 0.52 1000351.0 380000.0 0.53 0.74 0.9999 2073147 Maybridge1_007053 CC(C)(C)n1nn[nH]c1=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I14 compound treatment 942276.0 348000.0 0.49 1003823.0 384000.0 0.54 0.7282 0.9992 2073148 Maybridge1_007054 OC(=O)CCNC(=S)Nc1ccccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I15 compound treatment 975362.0 381000.0 0.54 970128.0 350000.0 0.49 0.7283 0.9987 2073149 Maybridge1_007055 CCCCCSc1nnc[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I16 compound treatment 948088.0 354000.0 0.5 961388.0 341000.0 0.48 0.6922 0.9996 2073150 Maybridge1_007056 Clc1ccccc1Nc2ncnc(n2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I17 compound treatment 1001314.0 407000.0 0.58 1001856.0 382000.0 0.53 0.7857 0.9992 1071543 Maybridge1_007057 c1cc2cc3ccccc3cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I18 compound treatment 933053.0 338000.0 0.48 940029.0 320000.0 0.45 0.656 0.9993 2073151 Maybridge1_007058 CCCCc1c(O)nc(S)nc1COC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I19 compound treatment 971319.0 377000.0 0.54 998860.0 379000.0 0.53 0.7525 1.0 2073152 Maybridge1_007059 CCOC(=O)c1c(/N=C/c2cc(Br)c(Br)cc2O)sc3CCCCc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I20 compound treatment 936483.0 342000.0 0.49 1027778.0 408000.0 0.57 0.746 0.9969 1181266 Maybridge1_007060 COCc1cc(=O)oc2cc(N)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I21 compound treatment 952059.0 357000.0 0.51 1007952.0 388000.0 0.54 0.7421 0.9995 2073153 Maybridge1_007061 NC(=N)NC(=N)Nc1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I22 compound treatment 931783.0 337000.0 0.48 974455.0 355000.0 0.49 0.6887 0.9999 2073154 Maybridge1_007062 NC(=N)NC(=N)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I23 mock treatment 967630.0 373000.0 0.53 1006565.0 387000.0 0.54 0.7564 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 I24 mock treatment 156113.0 -438000.0 -0.62 165113.0 -455000.0 -0.63 -0.8894 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J01 compound treatment 837604.0 243000.0 0.35 816325.0 196000.0 0.27 0.4381 0.9934 2073155 Maybridge1_007063 CCc1cc(O)nc(SCc2c(F)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J02 compound treatment 867423.0 273000.0 0.39 863962.0 244000.0 0.34 0.515 0.9979 1434301 Maybridge1_007064 CCc1cccc(CC)c1N2C(=O)CC(Sc3ccccc3N)C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J03 compound treatment 900157.0 306000.0 0.43 905296.0 285000.0 0.4 0.5887 0.999 1237906 Maybridge1_007065 CCCC1=NN(C(=O)c2ccc(Cl)cc2)C(=O)C1Cc3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J04 compound treatment 912363.0 318000.0 0.45 905136.0 285000.0 0.4 0.6008 0.998 1056222 Maybridge1_007066 Cc1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J05 compound treatment 931109.0 337000.0 0.48 953631.0 334000.0 0.47 0.6675 0.9999 2073156 Maybridge1_007067 COCc1cc(O)nc(SCC2CC2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J06 compound treatment 917293.0 323000.0 0.46 933621.0 314000.0 0.44 0.6339 0.9997 1084580 Maybridge1_007068 Nc1ccccc1SC(CC(=O)c2ccccc2)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J07 compound treatment 984530.0 390000.0 0.55 986542.0 367000.0 0.51 0.7537 0.9992 2073157 Maybridge1_007069 FC(F)(F)c1cccc(c1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J08 compound treatment 903907.0 309000.0 0.44 930195.0 310000.0 0.43 0.617 1.0 1928 Maybridge1_007070 [O-][N+](=O)c1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J09 compound treatment 1009775.0 415000.0 0.59 975815.0 356000.0 0.5 0.7685 0.9963 2073158 Maybridge1_007071 Cc1cccc(/N=C/c2cc(I)cc(I)c2O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J10 compound treatment 922463.0 328000.0 0.47 959276.0 339000.0 0.47 0.6644 1.0 2073159 Maybridge1_007072 COc1cc(NC(=S)NC(=O)c2ccccc2)c(OC)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J11 compound treatment 949915.0 355000.0 0.51 1001367.0 381000.0 0.53 0.7335 0.9997 1006360 Maybridge1_007073 Oc1nnc(O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J12 compound treatment 939501.0 345000.0 0.49 976505.0 357000.0 0.5 0.6985 1.0 1921383 Maybridge1_007074 C/C(=C\c1ccc(Cl)cc1)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J13 compound treatment 978326.0 384000.0 0.55 985253.0 365000.0 0.51 0.7462 0.9994 1042465 Maybridge1_007075 OCCNC(=S)NCC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J14 compound treatment 948013.0 353000.0 0.5 924760.0 305000.0 0.43 0.656 0.9965 2073160 Maybridge1_007076 C/C(=N\Cc1ccncc1)/c2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J15 compound treatment 977335.0 383000.0 0.54 1057401.0 437000.0 0.61 0.8163 0.9984 2073161 Maybridge1_007077 O=C/1OC(=N\C1=C/c2ccc(cc2)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J16 compound treatment 963151.0 369000.0 0.52 949449.0 330000.0 0.46 0.6956 0.9979 2073162 Maybridge1_007078 COc1cc(/C=N/CCC\N=C\c2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J17 compound treatment 979686.0 385000.0 0.55 1057183.0 437000.0 0.61 0.8185 0.9986 1018228 Maybridge1_007079 Nc1c(C#N)c(CC#N)nn1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J18 compound treatment 967194.0 373000.0 0.53 987218.0 367000.0 0.51 0.7369 0.9999 2073163 Maybridge1_007080 Oc1ccc(Br)cc1/C=N/c2ccc(cc2)S(=O)(=O)Nc3nccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J19 compound treatment 991862.0 397000.0 0.56 1008922.0 389000.0 0.54 0.7831 0.9998 1259024 Maybridge1_007081 Clc1ccc(NC(=S)Nc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J20 compound treatment 919626.0 325000.0 0.46 980950.0 361000.0 0.5 0.6829 0.9991 2073164 Maybridge1_007082 COC(=O)c1ccccc1N=NNc2cc(OC)cc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J21 compound treatment 952294.0 358000.0 0.51 1069855.0 450000.0 0.63 0.8034 0.9946 2073165 Maybridge1_007083 COc1ccc(Br)cc1/C=N/N=C/c2cc(Br)ccc2OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J22 compound treatment 927826.0 333000.0 0.47 993240.0 373000.0 0.52 0.7033 0.9989 1524469 Maybridge1_007084 O=C1N(Nc2ccccc2)C(=O)c3cccc4cccc1c34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J23 mock treatment 956351.0 362000.0 0.51 934083.0 314000.0 0.44 0.6736 0.9968 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 J24 mock treatment 142304.0 -452000.0 -0.64 135295.0 -485000.0 -0.68 -0.9327 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K01 compound treatment 816187.0 222000.0 0.32 779129.0 159000.0 0.22 0.3798 0.9853 1050488 Maybridge1_007085 OC(=O)CCCNc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K02 compound treatment 854300.0 260000.0 0.37 843715.0 224000.0 0.31 0.4819 0.9965 1267668 Maybridge1_007086 Fc1cccc(Cl)c1Cn2nnc(n2)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K03 compound treatment 886398.0 292000.0 0.41 853288.0 233000.0 0.33 0.5236 0.9928 2073166 Maybridge1_007087 CC/1(CCCC\C1=N\O)NO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K04 compound treatment 886097.0 292000.0 0.41 879864.0 260000.0 0.36 0.5495 0.9978 2073167 Maybridge1_007088 Cc1cc(O)nc(SCC(=O)C(C)(C)C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K05 compound treatment 885123.0 291000.0 0.41 925879.0 306000.0 0.43 0.5939 0.9999 2073168 Maybridge1_007089 OC(=O)C1(CC2CC3C1)CC(C2)(C3)C(F)(F)C(F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K06 compound treatment 875762.0 281000.0 0.4 928236.0 308000.0 0.43 0.5868 0.9993 2073169 Maybridge1_007090 Cc1cccc(NC(=N)NC(=N)N)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K07 compound treatment 945598.0 351000.0 0.5 948394.0 328000.0 0.46 0.6769 0.9991 1627929 Maybridge1_007091 Clc1ccc(cc1)C(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K08 compound treatment 869056.0 274000.0 0.39 936329.0 316000.0 0.44 0.588 0.9981 2073170 Maybridge1_007092 NC(=N)NC(=N)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K09 compound treatment 966255.0 372000.0 0.53 976091.0 356000.0 0.5 0.725 0.9995 1202748 Maybridge1_007093 COc1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K10 compound treatment 906911.0 312000.0 0.44 928201.0 308000.0 0.43 0.6181 0.9999 2073171 Maybridge1_007094 Cc1cc(NC(=N)NC(=N)N)ccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K11 compound treatment 930571.0 336000.0 0.48 928665.0 309000.0 0.43 0.6423 0.9987 1729064 Maybridge1_007095 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K12 compound treatment 867969.0 273000.0 0.39 907440.0 288000.0 0.4 0.5585 0.9999 2073172 Maybridge1_007096 Oc1cc(nc(n1)C2CC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K13 compound treatment 870025.0 275000.0 0.39 963632.0 344000.0 0.48 0.6159 0.995 2073173 Maybridge1_007097 CC1=CC(=O)C(=CC1=O)Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K14 compound treatment 865572.0 271000.0 0.39 982247.0 362000.0 0.51 0.6298 0.9911 1137690 Maybridge1_007098 OC(=O)CCNC(=S)Nc1cccc(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K15 compound treatment 971759.0 377000.0 0.54 998323.0 378000.0 0.53 0.7525 1.0 2073174 Maybridge1_007099 C1c2ccccc2-c3ncccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K16 compound treatment 921408.0 327000.0 0.46 969661.0 350000.0 0.49 0.6736 0.9997 1013598 Maybridge1_007100 NC(=N)NC(=N)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K17 compound treatment 981747.0 387000.0 0.55 970274.0 350000.0 0.49 0.7348 0.9982 724 Maybridge1_007101 CCn1cc(C(=O)O)c(=O)c2ccc(C)nc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K18 compound treatment 935539.0 341000.0 0.48 979954.0 360000.0 0.5 0.6979 0.9998 2073175 Maybridge1_007102 CCSc1nc(N)c(Br)c(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K19 compound treatment 968212.0 374000.0 0.53 970557.0 351000.0 0.49 0.7215 0.9991 1037873 Maybridge1_007103 Cc1c(cc2c(c1[N+](=O)[O-])C(C)(C)CC2(C)C)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K20 compound treatment 890643.0 296000.0 0.42 994344.0 374000.0 0.52 0.667 0.9943 1208794 Maybridge1_007104 CC1=CC2N=C(C)C=C(O)N2O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K21 compound treatment 948823.0 354000.0 0.5 973591.0 354000.0 0.49 0.705 0.9999 2073176 Maybridge1_007105 Cc1nc(S)nc(O)c1Cc2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K22 compound treatment 888863.0 294000.0 0.42 964046.0 344000.0 0.48 0.6353 0.9977 1027920 Maybridge1_007106 CC1=CC(C)(C)NC(=S)N1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K23 mock treatment 960077.0 366000.0 0.52 983137.0 363000.0 0.51 0.7257 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 K24 mock treatment 147721.0 -447000.0 -0.64 159581.0 -460000.0 -0.64 -0.9033 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L01 compound treatment 833698.0 239000.0 0.34 799755.0 180000.0 0.25 0.4178 0.9888 1659710 Maybridge1_007107 COc1ccccc1NC(=S)NCCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L02 compound treatment 852881.0 258000.0 0.37 829481.0 210000.0 0.29 0.4664 0.9936 1080211 Maybridge1_007108 CCc1cccc(CC)c1NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L03 compound treatment 894486.0 300000.0 0.43 905907.0 286000.0 0.4 0.5836 0.9994 2073177 Maybridge1_007109 CCCC1=NNC(=O)C1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L04 compound treatment 864698.0 270000.0 0.38 904856.0 285000.0 0.4 0.5526 0.9999 1002383 Maybridge1_007110 N#CC(=Cc1ccc2OCOc2c1)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L05 compound treatment 904880.0 310000.0 0.44 925248.0 305000.0 0.43 0.6131 0.9998 2073178 Maybridge1_007111 CCCc1nc(nc(O)c1CC2CC2)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L06 compound treatment 891999.0 297000.0 0.42 818276.0 198000.0 0.28 0.4947 0.9788 1604878 Maybridge1_007112 COc1cccc(Nc2nnc(S)s2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L07 compound treatment 913190.0 319000.0 0.45 925842.0 306000.0 0.43 0.6221 0.9995 2073179 Maybridge1_007113 FC(F)(F)c1cccc(c1)c2nnc(o2)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L08 compound treatment 892726.0 298000.0 0.42 954657.0 335000.0 0.47 0.6299 0.9988 2073180 Maybridge1_007114 COc1cccc(/C=N/N=C/c2cccc(OC)c2O)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L09 compound treatment 886431.0 292000.0 0.42 995708.0 376000.0 0.52 0.6641 0.9933 2073181 Maybridge1_007115 Oc1c(Br)cc(Br)cc1/C=N/c2ccc(Oc3ccc(Cl)cc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L10 compound treatment 914757.0 320000.0 0.46 893147.0 273000.0 0.38 0.5914 0.9961 2073182 Maybridge1_007116 C/C(=N\Cc1ccc2OCOc2c1)/c3ccccc3O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L11 compound treatment 924309.0 330000.0 0.47 939947.0 320000.0 0.45 0.6472 0.9997 1084579 Maybridge1_007117 Clc1ccc(Oc2ccc(NCN3C(=O)c4ccccc4C3=O)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L12 compound treatment 884054.0 289000.0 0.41 965966.0 346000.0 0.48 0.6324 0.9969 1012383 Maybridge1_007118 NC(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L13 compound treatment 910907.0 316000.0 0.45 926820.0 307000.0 0.43 0.6207 0.9997 1183837 Maybridge1_007119 CCOC(=O)c1ccc(NCN2C(=O)c3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L14 compound treatment 925744.0 331000.0 0.47 960204.0 340000.0 0.47 0.6686 1.0 2073183 Maybridge1_007120 CCOc1ccc(Br)cc1/C=C(\C)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L15 compound treatment 913796.0 319000.0 0.45 980534.0 361000.0 0.5 0.6766 0.9987 2073184 Maybridge1_007121 [O-][N+](=O)/C=C/c1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L16 compound treatment 897679.0 303000.0 0.43 958952.0 339000.0 0.47 0.6391 0.9989 2073185 Maybridge1_007122 C/C(=N\NC(=S)N)/c1ccc(Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L17 compound treatment 954686.0 360000.0 0.51 998880.0 379000.0 0.53 0.7358 0.9999 2073186 Maybridge1_007123 O=C/1OC(=N\C1=C/c2ccco2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L18 compound treatment 922887.0 328000.0 0.47 958381.0 338000.0 0.47 0.6639 1.0 1569211 Maybridge1_007124 COc1ccc(cc1)C(=O)CC2OC(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L19 compound treatment 925478.0 331000.0 0.47 969787.0 350000.0 0.49 0.6778 0.9998 1045646 Maybridge1_007125 Cc1ccc(CSC(=N)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L20 compound treatment 899762.0 305000.0 0.43 1002614.0 383000.0 0.53 0.6843 0.9947 2073187 Maybridge1_007126 CN(C)c1ccc(cc1)n2nnnc2S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L21 compound treatment 951225.0 357000.0 0.51 1026075.0 406000.0 0.57 0.7592 0.9985 1384061 Maybridge1_007127 Sc1nnc(NC2CCCCC2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L22 compound treatment 904118.0 310000.0 0.44 990418.0 370000.0 0.52 0.6766 0.9968 1040878 Maybridge1_007128 CN(C)N1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L23 mock treatment 911037.0 316000.0 0.45 982137.0 362000.0 0.51 0.6754 0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 L24 mock treatment 132832.0 -462000.0 -0.66 159288.0 -461000.0 -0.64 -0.9186 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M01 compound treatment 809569.0 215000.0 0.31 776242.0 156000.0 0.22 0.3703 0.9863 1153336 Maybridge1_007129 S(c1c(nc2ccccn12)c3ccccc3)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M02 compound treatment 878872.0 284000.0 0.4 807842.0 188000.0 0.26 0.4712 0.978 1304742 Maybridge1_007130 Cc1nc(SCc2c(F)cccc2Cl)nc(O)c1Cc3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M03 compound treatment 898490.0 304000.0 0.43 897663.0 278000.0 0.39 0.5795 0.9985 2073188 Maybridge1_007131 Cc1cnnc2ccc3nonc3c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M04 compound treatment 873941.0 279000.0 0.4 887465.0 268000.0 0.37 0.5448 0.9995 2073189 Maybridge1_007132 CCOC(=N)c1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M05 compound treatment 897096.0 303000.0 0.43 928362.0 308000.0 0.43 0.6084 1.0 1652029 Maybridge1_007133 Clc1ccc(CN2CCC(CC2)NC(=O)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M06 compound treatment 862350.0 268000.0 0.38 906631.0 287000.0 0.4 0.552 0.9997 2073190 Maybridge1_007134 Nc1ncnc(Nc2cccc(c2)C(F)(F)F)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M07 compound treatment 937091.0 343000.0 0.49 942709.0 323000.0 0.45 0.6627 0.9992 1684864 Maybridge1_007135 Brc1ccccc1C(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M08 compound treatment 906853.0 312000.0 0.44 913847.0 294000.0 0.41 0.6039 0.9992 2073191 Maybridge1_007136 CCOC(=N)c1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M09 compound treatment 916718.0 322000.0 0.46 853326.0 233000.0 0.33 0.5541 0.986 1607644 Maybridge1_007137 COc1ccc(CCNS(=O)(=O)c2ccc(Cl)c(Cl)c2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M10 compound treatment 899092.0 305000.0 0.43 919609.0 300000.0 0.42 0.6018 0.9998 2073192 Maybridge1_007138 NC(=N)NC(=N)Nc1ccc(Oc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M11 compound treatment 892320.0 298000.0 0.42 933189.0 313000.0 0.44 0.6083 0.9999 1513968 Maybridge1_007139 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M12 compound treatment 907697.0 313000.0 0.45 925036.0 305000.0 0.43 0.6158 0.9997 1471831 Maybridge1_007140 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M13 compound treatment 939325.0 345000.0 0.49 971827.0 352000.0 0.49 0.6937 1.0 686 Maybridge1_007141 C(Nc1ncnc2[nH]cnc12)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M14 compound treatment 894329.0 300000.0 0.43 964462.0 345000.0 0.48 0.6412 0.9982 1022398 Maybridge1_007142 Nc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M15 compound treatment 924044.0 329000.0 0.47 963058.0 343000.0 0.48 0.6697 0.9999 1074320 Maybridge1_007143 O=C1c2ccccc2-c3ncccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M16 compound treatment 910993.0 316000.0 0.45 923735.0 304000.0 0.42 0.6178 0.9995 2073193 Maybridge1_007144 CC(C)CCc1c(C)nc(SCC(=O)C(C)(C)C)nc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M17 compound treatment 962988.0 368000.0 0.52 981099.0 361000.0 0.5 0.7266 0.9998 1644993 Maybridge1_007145 Cc1nn(c(N)c1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M18 compound treatment 935675.0 341000.0 0.49 959953.0 340000.0 0.47 0.6783 0.9999 2073194 Maybridge1_007146 NC(=N)NC(=N)Nc1ccc2OCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M19 compound treatment 972640.0 378000.0 0.54 995944.0 376000.0 0.52 0.751 0.9999 2073195 Maybridge1_007147 Cc1cc(O)n(n1)c2cc(Cl)c(cc2Cl)S(=O)(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M20 compound treatment 913086.0 319000.0 0.45 943944.0 324000.0 0.45 0.6398 1.0 2073196 Maybridge1_007148 Cc1cc(O)nc(n1)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M21 compound treatment 951431.0 357000.0 0.51 961387.0 341000.0 0.48 0.6956 0.9995 2073197 Maybridge1_007149 COc1ccc(CCN/2C(=O)CS\C2=N/c3cc(Cl)cc(Cl)c3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M22 compound treatment 914150.0 320000.0 0.45 944416.0 324000.0 0.45 0.6414 1.0 2073198 Maybridge1_007150 COCc1cc(=O)oc2[nH]nc(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M23 mock treatment 962912.0 368000.0 0.52 960642.0 341000.0 0.48 0.7064 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 M24 mock treatment 549409.0 -45200.0 -0.06 753843.0 134000.0 0.19 0.0866 0.4387 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N01 compound treatment 827398.0 233000.0 0.33 826082.0 206000.0 0.29 0.4374 0.9975 2073199 Maybridge1_007151 [O-][N+](=O)c1cccc(c1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N02 compound treatment 869274.0 275000.0 0.39 817313.0 197000.0 0.28 0.4709 0.9853 2073200 Maybridge1_007152 Sc1nnnn1Cc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N03 compound treatment 910771.0 316000.0 0.45 901939.0 282000.0 0.39 0.5961 0.9978 1205916 Maybridge1_007153 CCCc1cc(=O)oc2cc(OCC(=O)OCC)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N04 compound treatment 853198.0 259000.0 0.37 896047.0 276000.0 0.39 0.5324 0.9997 2073201 Maybridge1_007154 Cc1cc(C)c(NC(=S)NN)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N05 compound treatment 927942.0 333000.0 0.47 897338.0 277000.0 0.39 0.6088 0.9949 1694603 Maybridge1_007155 CC(C(=O)NN)n1nnc(n1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N06 compound treatment 887465.0 293000.0 0.42 864287.0 244000.0 0.34 0.5355 0.995 1058453 Maybridge1_007156 N#CC(=Cc1c[nH]c2ccccc12)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N07 compound treatment 880931.0 286000.0 0.41 970715.0 351000.0 0.49 0.6339 0.9958 1643270 Maybridge1_007157 NNC(=O)CCn1nnc(n1)c2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N08 compound treatment 862074.0 267000.0 0.38 969816.0 350000.0 0.49 0.614 0.9924 2073202 Maybridge1_007158 CCO/C=C/1\SC(=S)NC1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N09 compound treatment 926989.0 332000.0 0.47 1044917.0 425000.0 0.59 0.7534 0.9937 2073203 Maybridge1_007159 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccccc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N10 compound treatment 856771.0 262000.0 0.37 951328.0 331000.0 0.46 0.5905 0.9943 2073204 Maybridge1_007160 CCOC(=O)c1ccc(NC(=S)NCCCN2CCOCC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N11 compound treatment 895324.0 301000.0 0.43 899511.0 280000.0 0.39 0.5781 0.9989 1487751 Maybridge1_007161 Cc1ccccc1NC(=S)NCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N12 compound treatment 918663.0 324000.0 0.46 1009691.0 390000.0 0.54 0.7103 0.9966 2073205 Maybridge1_007162 O=C/1OC(=N\C1=C/c2ccc(\C=C\3/N=C(OC3=O)c4ccccc4)cc2)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N13 compound treatment 873994.0 279000.0 0.4 952444.0 333000.0 0.46 0.6089 0.997 1264587 Maybridge1_007163 Cc1cccc(C)c1NC(=S)NCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N14 compound treatment 862858.0 268000.0 0.38 925142.0 305000.0 0.43 0.5708 0.9985 2073206 Maybridge1_007164 COc1ccccc1C=C(C#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N15 compound treatment 899502.0 305000.0 0.43 1031456.0 412000.0 0.57 0.7125 0.9904 2073207 Maybridge1_007165 Clc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N16 compound treatment 863406.0 269000.0 0.38 958828.0 339000.0 0.47 0.6046 0.9945 1056276 Maybridge1_007166 NC1=C(C#N)C2=CCCC2C3(CCCC3)C1(C#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N17 compound treatment 911182.0 317000.0 0.45 994764.0 375000.0 0.52 0.688 0.9972 2073208 Maybridge1_007167 Cc1cc(CSC(=N)N)c(CSC(=N)N)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N18 compound treatment 865923.0 271000.0 0.39 991546.0 372000.0 0.52 0.6393 0.9894 2073209 Maybridge1_007168 CCCCC(C(=O)N/N=C/c1ccc(OCC)c(OC)c1)C(=O)N/N=C/c2ccc(OCC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N19 compound treatment 918523.0 324000.0 0.46 1005067.0 385000.0 0.54 0.7056 0.9971 1719191 Maybridge1_007169 Cc1ccc(NC(=S)Nc2ccccn2)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N20 compound treatment 917075.0 323000.0 0.46 972581.0 353000.0 0.49 0.6721 0.9994 1506578 Maybridge1_007170 NNC(=S)Nc1ccc2OCCOc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N21 compound treatment 917207.0 323000.0 0.46 1031875.0 412000.0 0.57 0.7307 0.9938 1239520 Maybridge1_007171 COc1ccc(CCNC(=S)NCCc2ccc(OC)c(OC)c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N22 compound treatment 890978.0 296000.0 0.42 990123.0 370000.0 0.52 0.6631 0.9949 2073210 Maybridge1_007172 COc1ccc(CC/N=C(\C)/c2ccc3ccccc3c2)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N23 mock treatment 940707.0 346000.0 0.49 976802.0 357000.0 0.5 0.7 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 N24 mock treatment 706952.0 112000.0 0.16 626426.0 6500.0 0.01 0.1194 0.746 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O01 compound treatment 844955.0 250000.0 0.36 796797.0 177000.0 0.25 0.4262 0.9839 1278108 Maybridge1_007173 OC(=O)c1nonc1c2nonc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O02 compound treatment 837997.0 243000.0 0.35 771744.0 152000.0 0.21 0.3945 0.9722 2073211 Maybridge1_007174 S=C(NCc1cccs1)NC2CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O03 compound treatment 901173.0 307000.0 0.44 854814.0 235000.0 0.33 0.5399 0.9901 1922564 Maybridge1_007175 c1ccc(cc1)c2cc3c4nonc4ccc3nn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O04 compound treatment 858562.0 264000.0 0.38 853062.0 233000.0 0.33 0.4954 0.9974 1679982 Maybridge1_007176 Cc1nc(nc(O)c1CC2CC2)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O05 compound treatment 906827.0 312000.0 0.44 884296.0 264000.0 0.37 0.5747 0.9957 1426502 Maybridge1_007177 Clc1ccc(CN2CCC(CC2)NC(=O)c3ccccc3)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O06 compound treatment 839906.0 245000.0 0.35 879207.0 259000.0 0.36 0.5024 0.9998 2073212 Maybridge1_007178 NC(=N)NC(=N)Nc1cccc(C#C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O07 compound treatment 902343.0 308000.0 0.44 926989.0 307000.0 0.43 0.6123 0.9999 1152846 Maybridge1_007179 Clc1cccc(Cl)c1C(=O)NC2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O08 compound treatment 867867.0 273000.0 0.39 873315.0 253000.0 0.35 0.5247 0.9989 1393987 Maybridge1_007180 Nc1ncnc(Nc2nc(cs2)c3ccccc3)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O09 compound treatment 886285.0 292000.0 0.41 911767.0 292000.0 0.41 0.5811 1.0 1728517 Maybridge1_007181 COc1ccc(CCNS(=O)(=O)c2cc(C)c(Cl)cc2Cl)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O10 compound treatment 869234.0 275000.0 0.39 895714.0 276000.0 0.38 0.5482 1.0 2073213 Maybridge1_007182 COc1cc(NC(=N)NC(=N)N)cc(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O11 compound treatment 879801.0 285000.0 0.41 928487.0 309000.0 0.43 0.5911 0.9996 1498392 Maybridge1_007183 Brc1ccccc1C(=O)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O12 compound treatment 826032.0 231000.0 0.33 895548.0 276000.0 0.38 0.5046 0.997 1006238 Maybridge1_007184 Nc1ccc(cc1)S(=O)(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O13 compound treatment 883826.0 289000.0 0.41 929926.0 310000.0 0.43 0.5966 0.9997 1092526 Maybridge1_007185 c1cn2cc(nc2s1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O14 compound treatment 869971.0 275000.0 0.39 907892.0 288000.0 0.4 0.5609 0.9999 2073214 Maybridge1_007186 CC(=O)N(C1=NCCC(=O)S1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O15 compound treatment 883293.0 289000.0 0.41 906316.0 286000.0 0.4 0.5728 0.9999 2073215 Maybridge1_007187 Cc1ccc(cc1)C(=O)c2c(C)ccc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O16 compound treatment 880128.0 286000.0 0.41 932413.0 312000.0 0.44 0.5953 0.9994 2073216 Maybridge1_007188 CC(=C)Cc1c(C)nc(S)nc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O17 compound treatment 918586.0 324000.0 0.46 962642.0 343000.0 0.48 0.6638 0.9998 1716974 Maybridge1_007189 OC1CC(NC2(CCCC2)C1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O18 compound treatment 883931.0 289000.0 0.41 898331.0 278000.0 0.39 0.5655 0.9996 1256 Maybridge1_007190 Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O19 compound treatment 901392.0 307000.0 0.44 958477.0 339000.0 0.47 0.6424 0.9992 1176932 Maybridge1_007191 CC1CC(=O)c2c(F)c(F)cc3c(=O)c(cn1c23)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O20 compound treatment 905186.0 311000.0 0.44 926055.0 306000.0 0.43 0.6142 0.9999 2073217 Maybridge1_007192 Sc1nc2ccccc2c(=O)n1CC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O21 compound treatment 938658.0 344000.0 0.49 957395.0 337000.0 0.47 0.6788 0.9998 1023643 Maybridge1_007193 Nc1nc(O)cc(n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O22 compound treatment 876358.0 282000.0 0.4 901957.0 282000.0 0.39 0.5615 1.0 2073218 Maybridge1_007194 NC(=N)NC(=N)Nc1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O23 mock treatment 926402.0 332000.0 0.47 928648.0 309000.0 0.43 0.6381 0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 O24 mock treatment 526915.0 -67700.0 -0.1 555107.0 -64800.0 -0.09 -0.132 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P01 compound treatment 791714.0 197000.0 0.28 806952.0 187000.0 0.26 0.3827 0.9994 1183103 Maybridge1_007195 CC(C)c1ccc(NC(=S)NCCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P02 compound treatment 847819.0 253000.0 0.36 820048.0 200000.0 0.28 0.452 0.9921 1080218 Maybridge1_007196 O=C(NC(=S)Nc1ccccn1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P03 compound treatment 835900.0 241000.0 0.34 849236.0 229000.0 0.32 0.4688 0.9994 2073219 Maybridge1_007197 CC1=NNC(=O)C1Cc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P04 compound treatment 839739.0 245000.0 0.35 852017.0 232000.0 0.32 0.4754 0.9993 2073220 Maybridge1_007198 NC(=S)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P05 compound treatment 831502.0 237000.0 0.34 865510.0 246000.0 0.34 0.4804 1.0 2073221 Maybridge1_007199 CCCCCCCc1c(O)[nH]nc1COC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P06 compound treatment 857189.0 263000.0 0.37 880763.0 261000.0 0.36 0.5213 0.9999 1083209 Maybridge1_007200 S=C1SCN(CCc2ccccc2)CN1CCc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P07 compound treatment 842899.0 248000.0 0.35 885643.0 266000.0 0.37 0.5118 0.9997 1430187 Maybridge1_007201 COc1ccccc1NC(=S)NCCc2ccc(OC)c(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P08 compound treatment 849019.0 254000.0 0.36 907798.0 288000.0 0.4 0.5398 0.9987 2073222 Maybridge1_007202 S=C(NCCc1ccccc1)N2CCC(CCCC3CCN(CC3)C(=S)NCCc4ccccc4)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P09 compound treatment 836857.0 242000.0 0.34 891159.0 271000.0 0.38 0.5111 0.9989 2073223 Maybridge1_007203 Cc1ccc(Cl)cc1NC(=S)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P10 compound treatment 828563.0 234000.0 0.33 895930.0 276000.0 0.38 0.5075 0.9974 2073224 Maybridge1_007204 Oc1ccc(Br)cc1/C=N/c2ccc(F)c(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P11 compound treatment 841304.0 247000.0 0.35 895930.0 276000.0 0.38 0.5203 0.9989 2073225 Maybridge1_007205 Cc1cc(Cl)ccc1NC(=S)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P12 compound treatment 848713.0 254000.0 0.36 911845.0 292000.0 0.41 0.5434 0.9982 2073226 Maybridge1_007206 Clc1cccc(/C=C/2\N=C(OC2=O)c3ccccc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P13 compound treatment 840301.0 246000.0 0.35 901393.0 281000.0 0.39 0.5247 0.9983 2073227 Maybridge1_007207 N/C(=N\O)/Cc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P14 compound treatment 840587.0 246000.0 0.35 911991.0 292000.0 0.41 0.5354 0.9971 2073228 Maybridge1_007208 COc1ccccc1/C=C/2\N=C(OC2=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P15 compound treatment 855935.0 261000.0 0.37 918315.0 298000.0 0.42 0.5571 0.9984 2073229 Maybridge1_007209 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P16 compound treatment 897188.0 303000.0 0.43 911492.0 292000.0 0.41 0.5918 0.9996 2073230 Maybridge1_007210 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2C(=O)C=CC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P17 compound treatment 868274.0 274000.0 0.39 943169.0 323000.0 0.45 0.594 0.9973 2073231 Maybridge1_007211 [O-][N+](=O)/C=C/c1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P18 compound treatment 865449.0 271000.0 0.39 945626.0 326000.0 0.45 0.5936 0.9966 1063067 Maybridge1_007212 COc1ccc(CNc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P19 compound treatment 877497.0 283000.0 0.4 927496.0 308000.0 0.43 0.5878 0.9995 1003767 Maybridge1_007213 O=C1N(Cc2ccccc2)C(=O)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P20 compound treatment 849564.0 255000.0 0.36 937812.0 318000.0 0.44 0.5699 0.995 1107460 Maybridge1_007214 C=CCCN1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P21 compound treatment 849370.0 255000.0 0.36 925940.0 306000.0 0.43 0.558 0.9967 1076485 Maybridge1_007215 S=C1SCN(CN1C2CCCCC2)C3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P22 compound treatment 861196.0 267000.0 0.38 938275.0 318000.0 0.44 0.5821 0.9969 1627643 Maybridge1_007216 Clc1ccc(Oc2ccc(NC(=S)NCc3ccco3)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P23 mock treatment 834686.0 240000.0 0.34 880369.0 260000.0 0.36 0.4983 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.561 P24 mock treatment 522932.0 -71600.0 -0.1 606539.0 -13400.0 -0.02 -0.0852 -0.823 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A01 compound treatment 792670.0 221000.0 0.31 812608.0 202000.0 0.28 0.4212 0.9986 2073232 Maybridge1_007217 Clc1ccc(NC(=O)CC2S/C(=N/CC=C)/NC2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A02 compound treatment 791974.0 220000.0 0.31 813656.0 203000.0 0.28 0.4215 0.9988 2073233 Maybridge1_007218 NC(=N)SCc1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A03 compound treatment 818408.0 246000.0 0.35 821785.0 211000.0 0.29 0.4561 0.9963 1218556 Maybridge1_007219 Clc1ccc(cc1)C2SCC(=O)N2c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A04 compound treatment 819700.0 248000.0 0.35 842788.0 232000.0 0.32 0.4781 0.9991 2073234 Maybridge1_007220 OC(=O)CCS(=O)(=O)/C=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A05 compound treatment 857608.0 286000.0 0.41 861772.0 251000.0 0.35 0.535 0.9973 2073235 Maybridge1_007221 Cc1ccc(NC(=S)NNC(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A06 compound treatment 876995.0 305000.0 0.43 834924.0 224000.0 0.31 0.528 0.9872 1626568 Maybridge1_007222 CCc1cccc(C)c1NC(=O)CC(C)(C)CC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A07 compound treatment 885585.0 314000.0 0.45 880555.0 270000.0 0.38 0.5816 0.9965 1218008 Maybridge1_007223 Cc1ccc2[nH]c(=S)n(c3ccc(cc3)S(=O)(=O)N4CCCCC4)c(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A08 compound treatment 895872.0 324000.0 0.46 904339.0 294000.0 0.41 0.6154 0.9983 1558896 Maybridge1_007224 OC(=O)CCc1ccccc1OC(=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A09 compound treatment 873300.0 301000.0 0.43 882687.0 272000.0 0.38 0.5714 0.9982 2073236 Maybridge1_007225 [O-][N+](=O)/C=C/c1c(F)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A10 compound treatment 902799.0 331000.0 0.47 887792.0 277000.0 0.39 0.6061 0.9953 1019656 Maybridge1_007226 COc1ccc(Cl)cc1NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A11 compound treatment 896363.0 324000.0 0.46 886375.0 276000.0 0.38 0.5982 0.996 2073237 Maybridge1_007227 CCCc1ccc(NC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A12 compound treatment 897946.0 326000.0 0.46 899637.0 289000.0 0.4 0.6129 0.9976 1411224 Maybridge1_007228 Cn1cc(c2ccccc2C(=O)N)c(=O)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A13 compound treatment 903721.0 332000.0 0.47 893799.0 283000.0 0.4 0.6129 0.9961 2073238 Maybridge1_007229 [O-][N+](=O)/C=C/c1ccc(C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A14 compound treatment 914748.0 343000.0 0.49 885228.0 275000.0 0.38 0.6156 0.9929 2073239 Maybridge1_007230 CCCCCCCCCCCCSC1CC(=O)N(C1=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A15 compound treatment 927800.0 356000.0 0.51 917685.0 307000.0 0.43 0.6607 0.9966 2073240 Maybridge1_007231 COc1cc(cc(OC)c1OC)C2CC(=O)N(C(=O)C2)c3cc(C)on3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A16 compound treatment 907832.0 336000.0 0.48 914513.0 304000.0 0.42 0.6375 0.9983 1594868 Maybridge1_007232 Cc1ccc(NC(=O)C2CCCCC2C(=O)O)cc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A17 compound treatment 934543.0 362000.0 0.52 932748.0 322000.0 0.45 0.6823 0.9977 2073241 Maybridge1_007233 CC(CC(=O)O)CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A18 compound treatment 915849.0 344000.0 0.49 899737.0 289000.0 0.4 0.631 0.9955 2073242 Maybridge1_007234 CCOc1ccc(/C=C/2\CCc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A19 compound treatment 888102.0 316000.0 0.45 901787.0 291000.0 0.41 0.6051 0.9987 2073243 Maybridge1_007235 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A20 compound treatment 899821.0 328000.0 0.47 892057.0 282000.0 0.39 0.6073 0.9964 1509219 Maybridge1_007236 Brc1ccc2NC(=O)C3(OCCO3)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A21 compound treatment 895631.0 324000.0 0.46 871903.0 261000.0 0.36 0.5832 0.9934 1004667 Maybridge1_007237 CCCCNC(=S)NCCCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A22 compound treatment 858218.0 286000.0 0.41 855859.0 245000.0 0.34 0.5298 0.9963 1193653 Maybridge1_007238 O=C1CC(Nc2ccccc2)C(=O)N1c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A23 mock treatment 844615.0 273000.0 0.39 838134.0 228000.0 0.32 0.4986 0.9951 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 A24 mock treatment 150791.0 -421000.0 -0.6 144630.0 -466000.0 -0.65 -0.883 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B01 compound treatment 849131.0 277000.0 0.39 802171.0 192000.0 0.27 0.4677 0.9822 1229042 Maybridge1_007239 CC(C)Cc1ccc(cc1)C(=O)CC2OC(=O)c3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B02 compound treatment 852053.0 280000.0 0.4 863876.0 253000.0 0.35 0.5315 0.9982 1698232 Maybridge1_007240 OC(=O)C1CN(Cc2ccccc2Cl)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B03 compound treatment 948608.0 377000.0 0.54 922040.0 312000.0 0.43 0.6859 0.9946 1699918 Maybridge1_007241 COc1ccc(CN2C(SCC2=O)c3ccccn3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B04 compound treatment 927817.0 356000.0 0.51 905994.0 296000.0 0.41 0.6492 0.9948 1329181 Maybridge1_007242 Clc1ccc(cc1)C2NCCc3sccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B05 compound treatment 939719.0 368000.0 0.52 914600.0 304000.0 0.42 0.6697 0.9946 2073244 Maybridge1_007243 [O-][N+](=O)/C=C/c1ccc(OCC=C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B06 compound treatment 945950.0 374000.0 0.53 862595.0 252000.0 0.35 0.6246 0.9799 1479953 Maybridge1_007244 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(cc3)c4csnn4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B07 compound treatment 957782.0 386000.0 0.55 958020.0 348000.0 0.48 0.7306 0.9981 2073245 Maybridge1_007245 Fc1ccc(/C=C/2\CC/C(=C\c3ccc(F)cc3)/C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B08 compound treatment 898307.0 326000.0 0.46 883891.0 273000.0 0.38 0.5977 0.9953 2073246 Maybridge1_007246 Cc1cc(C(=O)C(F)(F)F)c(C)n1c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B09 compound treatment 969826.0 398000.0 0.57 974692.0 364000.0 0.51 0.7592 0.9986 2073247 Maybridge1_007247 O/N=C/C(=O)Nc1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B10 compound treatment 946349.0 374000.0 0.53 968029.0 358000.0 0.5 0.729 0.9995 1202826 Maybridge1_007248 CC(C)N(C(C)C)C(=O)NC(=O)c1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B11 compound treatment 956001.0 384000.0 0.55 954865.0 344000.0 0.48 0.7257 0.998 1011631 Maybridge1_007249 O=C(N1C(C=Cc2ccccc12)C#N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B12 compound treatment 925046.0 353000.0 0.5 923205.0 313000.0 0.44 0.6634 0.9976 2073248 Maybridge1_007250 FC(F)(F)c1cc(cc(c1)S(=O)(=O)Nc2cccc(c2)c3nnco3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B13 compound treatment 966448.0 394000.0 0.56 956958.0 347000.0 0.48 0.7383 0.9973 1259298 Maybridge1_007251 CCOC(=O)c1c(N)nc(SC)n1c2ccc(cc2)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B14 compound treatment 980700.0 409000.0 0.58 910866.0 300000.0 0.42 0.7072 0.9871 2073249 Maybridge1_007252 Fc1ccc2OCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B15 compound treatment 974457.0 402000.0 0.57 929908.0 319000.0 0.45 0.7197 0.9923 1492443 Maybridge1_007253 CSc1nsc(SC)c1C(=O)NC(=O)Nc2ccc(cc2)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B16 compound treatment 895523.0 323000.0 0.46 961417.0 351000.0 0.49 0.6714 0.9995 2073250 Maybridge1_007254 Cc1cc(oc(=O)c1)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B17 compound treatment 1019036.0 447000.0 0.64 993986.0 384000.0 0.53 0.8277 0.9963 2073251 Maybridge1_007255 CNC(=S)NNC(=N)c1ccccn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B18 compound treatment 881824.0 310000.0 0.44 884687.0 274000.0 0.38 0.5819 0.9975 2073252 Maybridge1_007256 COC(=O)c1cc2CS(=O)(=O)c3ccc(Cl)cc3-c2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B19 compound treatment 1001699.0 430000.0 0.61 974593.0 364000.0 0.51 0.7911 0.9958 1046067 Maybridge1_007257 CCOC(=O)c1csnn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B20 compound treatment 919599.0 348000.0 0.49 922235.0 312000.0 0.43 0.657 0.998 1429277 Maybridge1_007258 COC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccsc3C(=O)OC)C(=O)OC)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B21 compound treatment 886528.0 314000.0 0.45 953422.0 343000.0 0.48 0.6545 0.9994 1596341 Maybridge1_007259 CC(C)(CC(=O)O)Sc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B22 compound treatment 910796.0 339000.0 0.48 917424.0 307000.0 0.43 0.6434 0.9983 2073253 Maybridge1_007260 CC(=O)c1ccc(s1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B23 mock treatment 907133.0 335000.0 0.48 915866.0 305000.0 0.43 0.6381 0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 B24 mock treatment 155484.0 -417000.0 -0.59 132654.0 -478000.0 -0.67 -0.8901 -0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C01 compound treatment 809041.0 237000.0 0.34 787452.0 177000.0 0.25 0.4129 0.9883 2073254 Maybridge1_007261 CCOC(=O)c1ccc(NC(=S)N2CCN(CC2)C(=S)Nc3ccc(cc3)C(=O)OCC)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C02 compound treatment 851784.0 280000.0 0.4 824255.0 214000.0 0.3 0.4921 0.9899 2073255 Maybridge1_007262 Clc1ccc(C2SCC(=O)N2c3ccccn3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C03 compound treatment 897029.0 325000.0 0.46 873670.0 263000.0 0.37 0.5864 0.9935 2073256 Maybridge1_007263 C/C(=C\c1ccccc1)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C04 compound treatment 859256.0 287000.0 0.41 861818.0 251000.0 0.35 0.5367 0.9971 2073257 Maybridge1_007264 CC(SCSC(C)C(=O)O)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C05 compound treatment 851054.0 279000.0 0.4 909510.0 299000.0 0.42 0.5755 0.9997 2073258 Maybridge1_007265 Cc1ccc(NC(=S)NNC(C)(C)C)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C06 compound treatment 829951.0 258000.0 0.37 879191.0 269000.0 0.37 0.5244 0.9999 2073259 Maybridge1_007266 COc1cccc(/C=C/[N+](=O)[O-])c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C07 compound treatment 835141.0 263000.0 0.37 909928.0 299000.0 0.42 0.5599 0.9985 2073260 Maybridge1_007267 CCCCCCCCCCCCSc1nnc(N)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C08 compound treatment 864008.0 292000.0 0.42 910443.0 300000.0 0.42 0.5894 1.0 1142484 Maybridge1_007268 Fc1cccc(Cl)c1C2NC(=O)c3ccccc3N2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C09 compound treatment 882769.0 311000.0 0.44 929265.0 319000.0 0.44 0.6269 1.0 1706531 Maybridge1_007269 O=C1CSC(N1c2ccc(cc2)C3CCCCC3)c4cccnc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C10 compound treatment 856239.0 284000.0 0.4 913043.0 303000.0 0.42 0.5842 0.9998 2073261 Maybridge1_007270 COc1cc(OC)cc(c1)N2C(=O)C=CC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C11 compound treatment 844963.0 273000.0 0.39 870614.0 260000.0 0.36 0.531 0.9994 1664547 Maybridge1_007271 CCCc1ccc(NC(=S)NC(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C12 compound treatment 833878.0 262000.0 0.37 902943.0 293000.0 0.41 0.5517 0.999 2073262 Maybridge1_007272 COc1cc(OC)cc(/C=C/2\CCc3ccccc3C2=O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C13 compound treatment 866653.0 295000.0 0.42 947874.0 337000.0 0.47 0.629 0.9983 2073263 Maybridge1_007273 C/C(=C\c1ccc(C#N)cc1)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C14 compound treatment 850080.0 278000.0 0.4 879288.0 269000.0 0.37 0.5447 0.9997 2073264 Maybridge1_007274 [O-][N+](=O)/C=C/c1cccc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C15 compound treatment 914470.0 342000.0 0.49 970528.0 360000.0 0.5 0.6994 0.9999 1139439 Maybridge1_007275 Cc1cc(no1)N2C(SCC2=O)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C16 compound treatment 902294.0 330000.0 0.47 907679.0 297000.0 0.41 0.6252 0.9981 1204560 Maybridge1_007276 CSc1ccc(cc1)C(=O)C(CC(=O)c2ccc(Cl)cc2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C17 compound treatment 894105.0 322000.0 0.46 921927.0 311000.0 0.43 0.631 0.9997 2073265 Maybridge1_007277 CC1CC(=O)N(C(=O)C1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C18 compound treatment 875548.0 303000.0 0.43 854821.0 244000.0 0.34 0.5462 0.9932 2073266 Maybridge1_007278 Cc1cc(Cl)ccc1NC(=O)/C=N/O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C19 compound treatment 885009.0 313000.0 0.45 906079.0 296000.0 0.41 0.6062 0.9993 2073267 Maybridge1_007279 CCOC(=O)c1ccc(cc1)N2C(=O)C3CCC(C)CC3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C20 compound treatment 847596.0 276000.0 0.39 881510.0 271000.0 0.38 0.5444 0.9998 2073268 Maybridge1_007280 COc1ccc(cc1)C2Oc3ccc(Cl)cc3C=C2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C21 compound treatment 877928.0 306000.0 0.43 909945.0 300000.0 0.42 0.6029 0.9998 1934763 Maybridge1_007281 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(Br)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C22 compound treatment 825961.0 254000.0 0.36 872068.0 262000.0 0.36 0.5133 1.0 1145248 Maybridge1_007282 Fc1ccc(NC2CC(=O)N(C2=O)c3ccc(F)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C23 mock treatment 850868.0 279000.0 0.4 888641.0 278000.0 0.39 0.5547 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 C24 mock treatment 143896.0 -428000.0 -0.61 172301.0 -438000.0 -0.61 -0.8627 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D01 compound treatment 871707.0 300000.0 0.43 839847.0 229000.0 0.32 0.5275 0.99 2073269 Maybridge1_007283 C/C(=N\Cc1ccc(F)cc1)/c2ccccc2O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D02 compound treatment 839089.0 267000.0 0.38 888086.0 278000.0 0.39 0.5423 1.0 1601159 Maybridge1_007284 OC(=O)C1CN(Cc2ccc(Cl)cc2)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D03 compound treatment 944793.0 373000.0 0.53 946126.0 336000.0 0.47 0.7058 0.9981 1337825 Maybridge1_007285 S=C1SCN(Cc2ccncc2)CN1Cc3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D04 compound treatment 927986.0 356000.0 0.51 971680.0 361000.0 0.5 0.7141 1.0 2073270 Maybridge1_007286 Cc1ccc(C)n1c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D05 compound treatment 885520.0 313000.0 0.45 1004627.0 394000.0 0.55 0.7039 0.9946 2073271 Maybridge1_007287 OC(=O)c1ccccc1NC(=O)/C=N/Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D06 compound treatment 952709.0 381000.0 0.54 951468.0 341000.0 0.48 0.7191 0.9979 2073272 Maybridge1_007288 COc1ccc(/C=N/c2ccc(cc2)c3csnn3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D07 compound treatment 948245.0 376000.0 0.53 1006545.0 396000.0 0.55 0.7689 0.9999 2073273 Maybridge1_007289 O=C(NC(=S)Nc1cccnc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D08 compound treatment 959020.0 387000.0 0.55 992168.0 382000.0 0.53 0.7656 0.9999 2073274 Maybridge1_007290 Cc1cc(C(=O)C(F)(F)F)c(C)n1c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D09 compound treatment 964489.0 392000.0 0.56 1026283.0 416000.0 0.58 0.8047 0.9998 2073275 Maybridge1_007291 O=C1/C(=C/c2cccnc2)/CCc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D10 compound treatment 982308.0 410000.0 0.58 996038.0 386000.0 0.54 0.7928 0.9992 2073276 Maybridge1_007292 FC(F)(F)c1ccc(cc1)C(=O)NCCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D11 compound treatment 982307.0 410000.0 0.58 962951.0 353000.0 0.49 0.7602 0.9964 2073277 Maybridge1_007293 CC(C)c1ccc(/C=C/2\CCc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D12 compound treatment 935639.0 364000.0 0.52 922332.0 312000.0 0.44 0.6732 0.9963 2073278 Maybridge1_007294 CC(CSc1ccc(Cl)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D13 compound treatment 971778.0 400000.0 0.57 1014475.0 404000.0 0.56 0.8004 1.0 2073279 Maybridge1_007295 COC(=O)c1nnn(c1C(=O)OC)c2ccc(F)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D14 compound treatment 983778.0 412000.0 0.59 970840.0 360000.0 0.5 0.7694 0.9971 2073280 Maybridge1_007296 OC(=O)CC(Sc1ccc(Cl)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D15 compound treatment 1035051.0 463000.0 0.66 1049015.0 439000.0 0.61 0.8981 0.9993 1157422 Maybridge1_007297 CSc1nsc(SC)c1C(=O)NC(=O)Nc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D16 compound treatment 1019025.0 447000.0 0.64 1008183.0 398000.0 0.55 0.8417 0.9977 2073281 Maybridge1_007298 N#CCc1ccc(cc1)c2nnco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D17 compound treatment 1021407.0 449000.0 0.64 1003615.0 393000.0 0.55 0.8396 0.9971 2073282 Maybridge1_007299 COC(=O)c1sc(cc1CS(=O)(=O)c2ccc(Cl)cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D18 compound treatment 966942.0 395000.0 0.56 987420.0 377000.0 0.53 0.7688 0.9995 2073283 Maybridge1_007300 Cc1ccc(cc1)c2ncns2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D19 compound treatment 1007489.0 435000.0 0.62 986562.0 376000.0 0.52 0.8088 0.9966 1282916 Maybridge1_007301 O=C(NC(=O)c1csnn1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D20 compound treatment 974821.0 403000.0 0.57 1004032.0 394000.0 0.55 0.7932 0.9998 1487892 Maybridge1_007302 Cc1nc(C)c(C(=O)O)c(c2ccsc2)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D21 compound treatment 978375.0 406000.0 0.58 1038657.0 428000.0 0.6 0.8309 0.9999 2073284 Maybridge1_007303 CC(C)(C)c1ccc(OC(=O)c2csnn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D22 compound treatment 938641.0 367000.0 0.52 991302.0 381000.0 0.53 0.7442 1.0 2073285 Maybridge1_007304 Brc1ccc(s1)c2ccon2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D23 mock treatment 960746.0 389000.0 0.55 989149.0 379000.0 0.53 0.7643 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 D24 mock treatment 141853.0 -430000.0 -0.61 158041.0 -452000.0 -0.63 -0.8788 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E01 compound treatment 831530.0 259000.0 0.37 852068.0 242000.0 0.34 0.4992 0.999 1541047 Maybridge1_007305 CCOC(=O)c1ccc(NC(=S)N(Cc2ccccc2)C(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E02 compound treatment 876589.0 305000.0 0.43 909517.0 299000.0 0.42 0.6012 0.9998 2073286 Maybridge1_007306 C/C(=C\c1ccc(F)cc1)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E03 compound treatment 914201.0 342000.0 0.49 955357.0 345000.0 0.48 0.6842 1.0 2073287 Maybridge1_007307 CCCCCCCCCCCC/N=C(\C)/c1ccccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E04 compound treatment 878088.0 306000.0 0.44 979576.0 369000.0 0.51 0.6718 0.9965 2073288 Maybridge1_007308 FC(F)(F)c1ccc(cc1)N2C(SCC2=O)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E05 compound treatment 930338.0 358000.0 0.51 949812.0 339000.0 0.47 0.6949 0.9993 2073289 Maybridge1_007309 CC(C)(C)NNC(=S)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E06 compound treatment 960545.0 388000.0 0.55 1003041.0 393000.0 0.55 0.7778 1.0 2073290 Maybridge1_007310 Cn1c(N)c(C(C[N+](=O)[O-])c2ccc(Cl)cc2Cl)c(=O)n(C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E07 compound treatment 979676.0 408000.0 0.58 985256.0 375000.0 0.52 0.7795 0.9987 1598300 Maybridge1_007311 Fc1ccccc1c2nc3ccccc3c(=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E08 compound treatment 972502.0 400000.0 0.57 1009789.0 399000.0 0.56 0.7965 0.9999 2073291 Maybridge1_007312 CC(=O)c1ccccc1NC(=O)CSCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E09 compound treatment 969748.0 398000.0 0.57 945997.0 336000.0 0.47 0.7308 0.9956 1607615 Maybridge1_007313 CCC(C)c1ccc(NCN2C(=O)c3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E10 compound treatment 949738.0 378000.0 0.54 994928.0 384000.0 0.54 0.7589 1.0 2073292 Maybridge1_007314 FC(F)(F)c1ccc(cc1)c2nnc(S)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E11 compound treatment 950700.0 379000.0 0.54 980562.0 370000.0 0.52 0.7457 0.9998 2073293 Maybridge1_007315 C/C(=C\c1c2ccccc2cc3ccccc13)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E12 compound treatment 919853.0 348000.0 0.49 911166.0 301000.0 0.42 0.6463 0.9966 2073294 Maybridge1_007316 Cc1ccc(/C=C/2\CCc3ccccc3C2=O)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E13 compound treatment 940972.0 369000.0 0.52 960096.0 350000.0 0.49 0.7158 0.9993 2073295 Maybridge1_007317 CSc1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E14 compound treatment 938549.0 366000.0 0.52 970881.0 360000.0 0.5 0.724 0.9998 2073296 Maybridge1_007318 O/N=C/C(=O)Nc1cc(Cl)ccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E15 compound treatment 990897.0 419000.0 0.6 1036249.0 426000.0 0.59 0.8411 1.0 2073297 Maybridge1_007319 CSc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E16 compound treatment 954421.0 382000.0 0.54 1014507.0 404000.0 0.56 0.783 0.9998 2073298 Maybridge1_007320 NC(=S)Nc1ccc(F)c(F)c1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E17 compound treatment 1014349.0 442000.0 0.63 1055669.0 445000.0 0.62 0.8838 1.0 2073299 Maybridge1_007321 [O-][N+](=O)C1CCC(=O)NC1C2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E18 compound treatment 967795.0 396000.0 0.56 994877.0 384000.0 0.54 0.7771 0.9997 1034190 Maybridge1_007322 CC(=O)N1C(=O)c2ccccc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E19 compound treatment 1013389.0 441000.0 0.63 1033134.0 423000.0 0.59 0.8606 0.9995 2073300 Maybridge1_007323 Cc1onc(c1C(=O)NC(=S)Nc2ccc(cc2)C(C)(C)C)c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E20 compound treatment 958105.0 386000.0 0.55 923469.0 313000.0 0.44 0.6969 0.9936 2073301 Maybridge1_007324 Oc1cc2OCOc2cc1C(N3CCCCC3)c4ccc(cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E21 compound treatment 927658.0 356000.0 0.51 1046639.0 436000.0 0.61 0.7877 0.9958 1007115 Maybridge1_007325 Cc1sc2ccccc2[n+]1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E22 compound treatment 953328.0 381000.0 0.54 986411.0 376000.0 0.52 0.7542 0.9999 1071585 Maybridge1_007326 O=C1C=C(Nc2ccccc2)C(=O)N1c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E23 mock treatment 957288.0 385000.0 0.55 990164.0 380000.0 0.53 0.7618 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 E24 mock treatment 142943.0 -429000.0 -0.61 154018.0 -456000.0 -0.64 -0.8816 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F01 compound treatment 872431.0 300000.0 0.43 861479.0 251000.0 0.35 0.5496 0.9951 1199558 Maybridge1_007327 Cc1ccc(cc1)n2sc(=O)n(Cc3ccc(F)cc3)c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F02 compound treatment 918996.0 347000.0 0.49 909980.0 300000.0 0.42 0.6443 0.9966 2073302 Maybridge1_007328 OC(=O)C1CN(Cc2ccc(cc2)C(F)(F)F)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F03 compound treatment 896812.0 325000.0 0.46 1024148.0 414000.0 0.58 0.7345 0.9939 1372305 Maybridge1_007329 Clc1ccc2n(CN3CCN(Cn4nnc5cc(Cl)ccc45)C3)nnc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F04 compound treatment 972466.0 400000.0 0.57 983327.0 373000.0 0.52 0.7704 0.999 2073303 Maybridge1_007330 FC(F)(F)c1ccccc1C(=O)NNc2ccc(cc2)c3csnn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F05 compound treatment 964626.0 393000.0 0.56 1040111.0 430000.0 0.6 0.8185 0.9994 1208089 Maybridge1_007331 COc1ccc(cc1)N2CSCc3nc4ccccc4n3C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F06 compound treatment 1015595.0 444000.0 0.63 1006881.0 396000.0 0.55 0.837 0.9978 2073304 Maybridge1_007332 NC(=S)N/N=C/c1ccc(F)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F07 compound treatment 990631.0 419000.0 0.6 1034384.0 424000.0 0.59 0.839 1.0 1213772 Maybridge1_007333 O=C1NCCN=C(c2ccccc2)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F08 compound treatment 1019100.0 447000.0 0.64 964460.0 354000.0 0.49 0.7986 0.9922 2073305 Maybridge1_007334 N/C(=N\O)/c1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F09 compound treatment 1015629.0 444000.0 0.63 1015286.0 405000.0 0.56 0.8453 0.9985 2073306 Maybridge1_007335 Fc1ccc(/C=C/2\Cc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F10 compound treatment 975973.0 404000.0 0.57 1001513.0 391000.0 0.55 0.7918 0.9997 1212754 Maybridge1_007336 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(cc3)c4cnco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F11 compound treatment 1019230.0 447000.0 0.64 1020439.0 410000.0 0.57 0.854 0.9986 2073307 Maybridge1_007337 Clc1ccc(/C=C/2\CCc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F12 compound treatment 975125.0 403000.0 0.57 989627.0 379000.0 0.53 0.7792 0.9992 2073308 Maybridge1_007338 NS(=O)(=O)c1ccc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F13 compound treatment 1004575.0 432000.0 0.62 1040089.0 430000.0 0.6 0.8586 0.9999 2073309 Maybridge1_007339 Clc1cc(Cl)cc(N/C=N/C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F14 compound treatment 1004805.0 433000.0 0.62 984170.0 374000.0 0.52 0.8037 0.9966 1374387 Maybridge1_007340 COc1ccc(cc1)C2=NCCc3sccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F15 compound treatment 1040492.0 468000.0 0.67 1019574.0 409000.0 0.57 0.8745 0.997 2073310 Maybridge1_007341 CSc1nsc(SC)c1C(=O)NC(=O)Nc2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F16 compound treatment 976466.0 404000.0 0.58 1034164.0 424000.0 0.59 0.8245 0.9999 2073311 Maybridge1_007342 Clc1ccc(OCc2ccsc2C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F17 compound treatment 1013336.0 441000.0 0.63 1028721.0 418000.0 0.58 0.8562 0.9993 2073312 Maybridge1_007343 CC1CC(=O)c2cc(Cl)ccc2S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F18 compound treatment 994017.0 422000.0 0.6 982727.0 372000.0 0.52 0.7914 0.9974 2073313 Maybridge1_007344 OC(=O)c1sccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F19 compound treatment 985999.0 414000.0 0.59 1021732.0 411000.0 0.57 0.8218 0.9999 1173364 Maybridge1_007345 O=C(NC(=O)c1csnn1)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F20 compound treatment 1015307.0 443000.0 0.63 1034185.0 424000.0 0.59 0.8636 0.9995 2073314 Maybridge1_007346 COC(=O)c1cc2sccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F21 compound treatment 1045316.0 473000.0 0.67 1077375.0 467000.0 0.65 0.9364 0.9999 2073315 Maybridge1_007347 [O-][N+](=O)c1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F22 compound treatment 970089.0 398000.0 0.57 979438.0 369000.0 0.51 0.7641 0.9989 2073316 Maybridge1_007348 Cc1cn(CCC#N)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F23 mock treatment 1017275.0 445000.0 0.63 1004356.0 394000.0 0.55 0.8362 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 F24 mock treatment 158104.0 -414000.0 -0.59 137118.0 -473000.0 -0.66 -0.8831 -0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G01 compound treatment 810228.0 238000.0 0.34 825934.0 215000.0 0.3 0.452 0.9982 1206001 Maybridge1_007349 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccs4)C(=O)CC(C)(C)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G02 compound treatment 857197.0 285000.0 0.41 871565.0 261000.0 0.36 0.5442 0.9986 1304403 Maybridge1_007350 Cc1onc(c1C(=O)NCc2csc3ccccc23)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G03 compound treatment 901712.0 330000.0 0.47 902716.0 292000.0 0.41 0.6197 0.9976 2073317 Maybridge1_007351 CCCCCCCCCCCCN1CSC(=S)N(CCCCCCCCCCCC)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G04 compound treatment 899209.0 327000.0 0.47 946108.0 336000.0 0.47 0.66 1.0 2073318 Maybridge1_007352 C/C(=C\c1ccc(Cl)cc1Cl)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G05 compound treatment 922860.0 351000.0 0.5 900156.0 290000.0 0.4 0.6385 0.9945 2073319 Maybridge1_007353 CCOC(=O)c1ccc(NC(=S)NNC(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G06 compound treatment 926535.0 354000.0 0.5 953234.0 343000.0 0.48 0.6945 0.9997 2073320 Maybridge1_007354 COc1ccc(cc1)C(C[N+](=O)[O-])c2c(N)n(C)c(=O)n(C)c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G07 compound treatment 962009.0 390000.0 0.55 998427.0 388000.0 0.54 0.7747 0.9999 2073321 Maybridge1_007355 Nc1ccccc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G08 compound treatment 939390.0 367000.0 0.52 966245.0 356000.0 0.5 0.7203 0.9997 2073322 Maybridge1_007356 FC(F)(F)c1ccc(cc1)N2C(SCC2=O)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G09 compound treatment 967321.0 395000.0 0.56 996818.0 386000.0 0.54 0.7785 0.9998 2073323 Maybridge1_007357 O=C1N(CNc2cccc(C#C)c2)C(=O)c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G10 compound treatment 907953.0 336000.0 0.48 959572.0 349000.0 0.49 0.6821 1.0 2073324 Maybridge1_007358 COc1cc(OC)cc(/C=C(\C)/[N+](=O)[O-])c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G11 compound treatment 944065.0 372000.0 0.53 970841.0 360000.0 0.5 0.7295 0.9997 1075529 Maybridge1_007359 OC(=O)CSCSCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G12 compound treatment 895923.0 324000.0 0.46 918786.0 308000.0 0.43 0.6297 0.9994 2073325 Maybridge1_007360 COc1ccc(/C=C/2\CCc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G13 compound treatment 977921.0 406000.0 0.58 845038.0 235000.0 0.33 0.6395 0.9639 2073326 Maybridge1_007361 CSc1ccc(/C=C/[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G14 compound treatment 966361.0 394000.0 0.56 980103.0 370000.0 0.52 0.761 0.9991 2073327 Maybridge1_007362 CCOC(=O)C1C(C(C(=O)OCC)C(O)(NC1(O)C(F)(F)F)C(F)(F)F)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G15 compound treatment 985436.0 413000.0 0.59 983549.0 373000.0 0.52 0.7836 0.9982 2073328 Maybridge1_007363 Cc1ccc2oc(=S)[nH]c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G16 compound treatment 966467.0 394000.0 0.56 982527.0 372000.0 0.52 0.7635 0.9992 2073329 Maybridge1_007364 FC(F)(F)Oc1ccc(NC2=NCCCS2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G17 compound treatment 971886.0 400000.0 0.57 967020.0 357000.0 0.5 0.7537 0.9978 2073330 Maybridge1_007365 Clc1cc(Cl)cc(c1)N2C(=O)CCCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G18 compound treatment 948627.0 377000.0 0.54 975785.0 365000.0 0.51 0.739 0.9997 1921512 Maybridge1_007366 OCC12COC3N2C(OC1)c4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G19 compound treatment 979050.0 407000.0 0.58 1043237.0 433000.0 0.6 0.8361 0.9998 2073331 Maybridge1_007367 CCC1(C)CC(=O)N(C(=O)C1)c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G20 compound treatment 926980.0 355000.0 0.5 892304.0 282000.0 0.39 0.6349 0.9924 2073332 Maybridge1_007368 Cc1ccccc1C(=O)N2N=C(Nc3ccccc3)SC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G21 compound treatment 894047.0 322000.0 0.46 955054.0 345000.0 0.48 0.6636 0.9997 1016108 Maybridge1_007369 OC(=O)Cc1csc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G22 compound treatment 913855.0 342000.0 0.49 953422.0 343000.0 0.48 0.6819 1.0 2073333 Maybridge1_007370 COc1cccc(/C=C/[N+](=O)[O-])c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G23 mock treatment 926206.0 354000.0 0.5 971544.0 361000.0 0.5 0.7122 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 G24 mock treatment 146757.0 -425000.0 -0.6 158209.0 -452000.0 -0.63 -0.8737 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H01 compound treatment 831044.0 259000.0 0.37 850253.0 240000.0 0.33 0.4969 0.9988 1642823 Maybridge1_007371 COc1ccccc1CCNC(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H02 compound treatment 883972.0 312000.0 0.44 864480.0 254000.0 0.35 0.5642 0.9938 2073334 Maybridge1_007372 CSc1nnc(o1)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H03 compound treatment 889960.0 318000.0 0.45 989636.0 379000.0 0.53 0.6936 0.9969 1003758 Maybridge1_007373 NC(=O)NNc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H04 compound treatment 927443.0 355000.0 0.51 926980.0 317000.0 0.44 0.6695 0.9977 2073335 Maybridge1_007374 Clc1cccc(c1)c2cnco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H05 compound treatment 936492.0 364000.0 0.52 1007406.0 397000.0 0.55 0.7579 0.9995 2073336 Maybridge1_007375 OC(=O)c1ccccc1C(=O)Nc2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H06 compound treatment 936265.0 364000.0 0.52 915866.0 305000.0 0.43 0.6674 0.9953 2073337 Maybridge1_007376 C(=N/c1ccc(cc1)c2csnn2)\c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H07 compound treatment 998911.0 427000.0 0.61 982457.0 372000.0 0.52 0.7961 0.997 1584836 Maybridge1_007377 O=c1n(CN2CCCCC2)nc(c3ccccc3)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H08 compound treatment 981817.0 410000.0 0.58 984219.0 374000.0 0.52 0.7806 0.9985 2073338 Maybridge1_007378 N/C(=N\OC(=O)c1ccccc1)/c2ccc(cc2)c3csnn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H09 compound treatment 958067.0 386000.0 0.55 962287.0 352000.0 0.49 0.7351 0.9984 1403274 Maybridge1_007379 CN1CNc2c(C1)c(=O)n(C)c(=O)n2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H10 compound treatment 895839.0 324000.0 0.46 964479.0 354000.0 0.49 0.6747 0.9994 2073339 Maybridge1_007380 COC(=O)CSc1nc2ccc(Cl)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H11 compound treatment 933405.0 361000.0 0.51 1021764.0 411000.0 0.57 0.769 0.9985 1098997 Maybridge1_007381 CCC1(O)C(=O)OCc2c1cc3-c4nc5ccccc5cc4Cn3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H12 compound treatment 931226.0 359000.0 0.51 965704.0 355000.0 0.5 0.7115 0.9999 1452355 Maybridge1_007382 CC(CS(=O)(=O)c1ccc(Cl)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H13 compound treatment 973414.0 401000.0 0.57 1046616.0 436000.0 0.61 0.8337 0.9995 2073340 Maybridge1_007383 CSc1nc(N)c(C#N)n1Cc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H14 compound treatment 969943.0 398000.0 0.57 983788.0 373000.0 0.52 0.7683 0.9991 1422458 Maybridge1_007384 COc1ccc(cc1)C2NCCc3sccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H15 compound treatment 1019703.0 448000.0 0.64 980981.0 371000.0 0.52 0.8155 0.9947 1702639 Maybridge1_007385 Clc1cc(Cl)c2nc(sc2c1)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H16 compound treatment 958609.0 387000.0 0.55 1006093.0 396000.0 0.55 0.7789 1.0 2073341 Maybridge1_007386 Cc1ccc(C)n1c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H17 compound treatment 995608.0 424000.0 0.6 1022651.0 412000.0 0.57 0.8324 0.9997 2073342 Maybridge1_007387 CCOC(=O)N/N=C/1\CC(C)S(=O)(=O)c2ccc(Cl)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H18 compound treatment 964479.0 392000.0 0.56 946368.0 336000.0 0.47 0.7259 0.9962 2073343 Maybridge1_007388 Cc1noc(C)c1C(=O)NC(=N)C2(CC3CC4CC(C3)C2)C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H19 compound treatment 986160.0 414000.0 0.59 1031577.0 421000.0 0.59 0.8317 1.0 2073344 Maybridge1_007389 O=C(NC(=O)c1csnn1)Nc2ncccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H20 compound treatment 847529.0 275000.0 0.39 969057.0 359000.0 0.5 0.6307 0.9927 2073345 Maybridge1_007390 FC(F)(F)c1ccc(/C=C\2/CSc3sccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H21 compound treatment 986391.0 414000.0 0.59 1008004.0 398000.0 0.55 0.8087 0.9995 2073346 Maybridge1_007391 Cc1noc(C)c1c2nc(CSc3ccc(Cl)cc3)no2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H22 compound treatment 951620.0 380000.0 0.54 952914.0 342000.0 0.48 0.7194 0.9981 1358842 Maybridge1_007392 Cc1cn(CCC(=O)O)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H23 mock treatment 963747.0 392000.0 0.56 995739.0 385000.0 0.54 0.7738 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 H24 mock treatment 143299.0 -429000.0 -0.61 130601.0 -480000.0 -0.67 -0.9044 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I01 compound treatment 836907.0 265000.0 0.38 825311.0 215000.0 0.3 0.4782 0.9936 2073347 Maybridge1_007393 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(s4)[N+](=O)[O-])C(=O)CC(C)(C)C3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I02 compound treatment 867813.0 296000.0 0.42 889771.0 279000.0 0.39 0.5729 0.9993 2073348 Maybridge1_007394 FC(F)(F)c1ccc(cc1)C(=O)OCCc2csc3ccccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I03 compound treatment 933179.0 361000.0 0.51 974249.0 364000.0 0.51 0.7219 1.0 1609960 Maybridge1_007395 Clc1ccc(cc1Cl)N2C(SCC2=O)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I04 compound treatment 910374.0 338000.0 0.48 952371.0 342000.0 0.48 0.6774 1.0 2073349 Maybridge1_007396 NC(=N)SCc1cc2ccccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I05 compound treatment 939480.0 367000.0 0.52 1007911.0 397000.0 0.55 0.7614 0.9996 2073350 Maybridge1_007397 CC(C)(C)NNC(=S)Nc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I06 compound treatment 934607.0 363000.0 0.52 959181.0 349000.0 0.49 0.7085 0.9996 2073351 Maybridge1_007398 Cn1c(N)c(C(C[N+](=O)[O-])c2ccccc2Cl)c(=O)n(C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I07 compound treatment 946674.0 375000.0 0.53 976940.0 367000.0 0.51 0.7381 0.9998 2073352 Maybridge1_007399 N#CCCSc1nc2ccccc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I08 compound treatment 908003.0 336000.0 0.48 950739.0 340000.0 0.47 0.6734 1.0 1689513 Maybridge1_007400 Clc1ccc(cc1)N2C(=O)c3ccncc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I09 compound treatment 956217.0 384000.0 0.55 963853.0 353000.0 0.49 0.7348 0.9987 1648925 Maybridge1_007401 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccccc3Oc4ccc(Cl)cc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I10 compound treatment 924123.0 352000.0 0.5 975106.0 365000.0 0.51 0.7136 1.0 2073353 Maybridge1_007402 COc1cc(OC)cc(c1)C2NC(CS2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I11 compound treatment 938997.0 367000.0 0.52 996191.0 386000.0 0.54 0.7494 0.9999 2073354 Maybridge1_007403 OC(=O)CCSCSCCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I12 compound treatment 903771.0 332000.0 0.47 978306.0 368000.0 0.51 0.6963 0.9991 1184785 Maybridge1_007404 CC1(C)CC2=C(C3CCCCC3O2)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I13 compound treatment 938567.0 366000.0 0.52 972189.0 362000.0 0.5 0.7253 0.9999 2073355 Maybridge1_007405 [O-][N+](=O)c1cc(ccc1N2CCSCC2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I14 compound treatment 971661.0 400000.0 0.57 931469.0 321000.0 0.45 0.7184 0.993 2073356 Maybridge1_007406 CCOC(=O)C1C(C(C(=O)OCC)C(O)(NC1(O)C(F)(F)F)C(F)(F)F)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I15 compound treatment 1001605.0 430000.0 0.61 1024476.0 414000.0 0.58 0.8402 0.9996 1421594 Maybridge1_007407 S=C1SCN(CC2CC2)CN1CC3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I16 compound treatment 960622.0 389000.0 0.55 947268.0 337000.0 0.47 0.7229 0.9967 2073357 Maybridge1_007408 CCOC(=O)C1C(C(C(=O)OCC)C(O)(NC1(O)C(F)(F)F)C(F)(F)F)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I17 compound treatment 991261.0 419000.0 0.6 980491.0 370000.0 0.52 0.7865 0.9974 2073358 Maybridge1_007409 [O-][N+](=O)/C=C/c1cc(Br)cs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I18 compound treatment 935423.0 363000.0 0.52 990956.0 381000.0 0.53 0.7406 0.9999 2073359 Maybridge1_007410 Clc1ccc(cc1Cl)N2CCCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I19 compound treatment 968212.0 396000.0 0.56 930814.0 320000.0 0.45 0.7143 0.9934 1413447 Maybridge1_007411 OC(=O)COCC(=O)Nc1ccc(I)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I20 compound treatment 927819.0 356000.0 0.51 983457.0 373000.0 0.52 0.7256 0.9999 2073360 Maybridge1_007412 CC(C)(C)c1ccc(cc1)C(=O)N2N=C(Nc3ccccc3)SC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I21 compound treatment 956757.0 385000.0 0.55 945497.0 335000.0 0.47 0.7173 0.9969 2073361 Maybridge1_007413 C/C(=C\c1ccc2OCOc2c1)/[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I22 compound treatment 928415.0 356000.0 0.51 959753.0 349000.0 0.49 0.7028 0.9998 2073362 Maybridge1_007414 CCOC(=O)CNc1ccc(OC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I23 mock treatment 980940.0 409000.0 0.58 990326.0 380000.0 0.53 0.7858 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 I24 mock treatment 141288.0 -431000.0 -0.61 151273.0 -459000.0 -0.64 -0.886 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J01 compound treatment 834831.0 263000.0 0.37 853137.0 243000.0 0.34 0.5036 0.9988 2073363 Maybridge1_007415 NC(=O)NCc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J02 compound treatment 831702.0 260000.0 0.37 900652.0 290000.0 0.4 0.5473 0.9989 1162604 Maybridge1_007416 CNc1scnc1S(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J03 compound treatment 917947.0 346000.0 0.49 982137.0 372000.0 0.52 0.7144 0.9997 2073364 Maybridge1_007417 CC(C)c1ccc(/C=C/[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J04 compound treatment 879623.0 308000.0 0.44 959573.0 349000.0 0.49 0.6536 0.9986 2073365 Maybridge1_007418 Cn1ncc2C(=O)CS(=O)(=O)Cc21 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J05 compound treatment 882429.0 310000.0 0.44 951760.0 341000.0 0.48 0.6487 0.9993 2073366 Maybridge1_007419 NC(=S)/C(=C/c1ccc(Cl)cc1Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J06 compound treatment 905942.0 334000.0 0.47 983278.0 373000.0 0.52 0.7034 0.999 1079133 Maybridge1_007420 Cc1nc(C#N)c(C#N)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J07 compound treatment 956691.0 385000.0 0.55 984631.0 374000.0 0.52 0.7558 0.9997 2073367 Maybridge1_007421 CCCCCCCCCCCCSC(=S)c1c(C)nn(c1O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J08 compound treatment 886235.0 314000.0 0.45 964557.0 354000.0 0.49 0.6651 0.9987 2073368 Maybridge1_007422 N/C(=N\OC(=O)c1ccc(Cl)cc1)/c2ccc(cc2)c3csnn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J09 compound treatment 930124.0 358000.0 0.51 1015628.0 405000.0 0.57 0.7596 0.9986 1611910 Maybridge1_007423 Cn1c2NCN(Cc2c(=O)n(C)c1=O)C3CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J10 compound treatment 920713.0 349000.0 0.5 977238.0 367000.0 0.51 0.7123 0.9999 2073369 Maybridge1_007424 NC(=O)CSc1nc2ccc(Cl)cc2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J11 compound treatment 903568.0 331000.0 0.47 1011934.0 401000.0 0.56 0.7293 0.9963 2073370 Maybridge1_007425 COC(=O)c1nnn(c1O)c2ccc(cc2)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J12 compound treatment 906248.0 334000.0 0.48 964575.0 354000.0 0.49 0.6853 0.9998 2073371 Maybridge1_007426 CCOC(=O)c1cnc2SCCn2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J13 compound treatment 955309.0 383000.0 0.54 1011162.0 401000.0 0.56 0.7806 0.9999 1205660 Maybridge1_007427 CC(C)Oc1cccc(NC(=O)c2ccccc2C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J14 compound treatment 923557.0 351000.0 0.5 856165.0 246000.0 0.34 0.5958 0.9831 2073372 Maybridge1_007428 CCOC(=O)c1ncoc1c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J15 compound treatment 959552.0 387000.0 0.55 991353.0 381000.0 0.53 0.7653 0.9998 1161071 Maybridge1_007429 Clc1cc(Cl)c2nc(sc2c1)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J16 compound treatment 958809.0 387000.0 0.55 1002250.0 392000.0 0.55 0.7753 1.0 2073373 Maybridge1_007430 Cc1ccc(C)n1c2ccc(/C=N/Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J17 compound treatment 931578.0 360000.0 0.51 992545.0 382000.0 0.53 0.7383 0.9998 1039635 Maybridge1_007431 Clc1ccc2SCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J18 compound treatment 887253.0 315000.0 0.45 982957.0 373000.0 0.52 0.6843 0.9973 2073374 Maybridge1_007432 COC(=O)c1sccc1c2ccc(o2)C(=O)/C=C/N(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J19 compound treatment 964123.0 392000.0 0.56 946377.0 336000.0 0.47 0.7255 0.9963 2073375 Maybridge1_007433 O=C(NC(=O)c1csnn1)Nc2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J20 compound treatment 916814.0 345000.0 0.49 983338.0 373000.0 0.52 0.7144 0.9996 2073376 Maybridge1_007434 FC(F)(F)Oc1ccc(cc1)C2=NCCc3sccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J21 compound treatment 948562.0 376000.0 0.54 990316.0 380000.0 0.53 0.7532 1.0 1196266 Maybridge1_007435 Cc1noc(C)c1c2nc(CSc3ccccn3)no2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J22 compound treatment 904264.0 332000.0 0.47 964152.0 354000.0 0.49 0.6829 0.9998 2073377 Maybridge1_007436 Cc1c2C(=O)CCn2c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J23 mock treatment 959095.0 387000.0 0.55 943547.0 333000.0 0.46 0.7177 0.9964 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 J24 mock treatment 122942.0 -449000.0 -0.64 155841.0 -455000.0 -0.63 -0.9 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K01 compound treatment 1055644.0 484000.0 0.69 968029.0 358000.0 0.5 0.8389 0.9876 2073378 Maybridge1_007437 CC1=N/C(=C\c2ccc3OCOc3c2)/C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K02 compound treatment 870347.0 298000.0 0.42 890436.0 280000.0 0.39 0.5761 0.9991 2073379 Maybridge1_007438 OC(=O)CS/C=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K03 compound treatment 898181.0 326000.0 0.46 905518.0 295000.0 0.41 0.6189 0.9982 2073380 Maybridge1_007439 Cc1ccc(CSc2ccccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K04 compound treatment 902885.0 331000.0 0.47 944951.0 335000.0 0.47 0.6625 1.0 1661485 Maybridge1_007440 Cc1cccc(c1O)C2(O)C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K05 compound treatment 906376.0 334000.0 0.48 921266.0 311000.0 0.43 0.6427 0.9989 2073381 Maybridge1_007441 O=C(Nc1ccccc1)OCCSc2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K06 compound treatment 876931.0 305000.0 0.43 944821.0 334000.0 0.47 0.6363 0.9993 2073382 Maybridge1_007442 COc1cccc(/C=C(\C)/[N+](=O)[O-])c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K07 compound treatment 930598.0 359000.0 0.51 945359.0 335000.0 0.47 0.6908 0.999 2073383 Maybridge1_007443 Cc1cc(Br)c(NC(=S)N)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K08 compound treatment 897280.0 325000.0 0.46 928210.0 318000.0 0.44 0.6404 0.9998 2073384 Maybridge1_007444 CC1=CC(=O)N(C1=O)c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K09 compound treatment 923584.0 352000.0 0.5 901013.0 291000.0 0.41 0.64 0.9946 1186215 Maybridge1_007445 OC(=O)CCC(=O)Nc1ccccc1Oc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K10 compound treatment 864634.0 293000.0 0.42 944488.0 334000.0 0.47 0.6236 0.9984 2073385 Maybridge1_007446 NC(=S)N/N=C/c1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K11 compound treatment 913174.0 341000.0 0.49 932377.0 322000.0 0.45 0.6605 0.9993 1112791 Maybridge1_007447 COc1ccc(cc1)C(=C2C=CC(=NO)C=C2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K12 compound treatment 885382.0 313000.0 0.45 960679.0 350000.0 0.49 0.6605 0.9989 1047662 Maybridge1_007448 C1CN=C(C(=N1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K13 compound treatment 932568.0 360000.0 0.51 996295.0 386000.0 0.54 0.743 0.9997 2073386 Maybridge1_007449 C/C(=N\NC(=O)N)/c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K14 compound treatment 898766.0 327000.0 0.46 941642.0 331000.0 0.46 0.6551 1.0 2073387 Maybridge1_007450 CCOC(=O)C1C(C(C(=O)OCC)C(O)(NC1(O)C(F)(F)F)C(F)(F)F)c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K15 compound treatment 964065.0 392000.0 0.56 1009744.0 399000.0 0.56 0.788 1.0 2073388 Maybridge1_007451 Fc1ccc(cc1Cl)N2C(=O)CSCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K16 compound treatment 925178.0 353000.0 0.5 952012.0 342000.0 0.48 0.6919 0.9997 1171426 Maybridge1_007452 CCOC(=O)Nc1cc(ccc1C(=O)OC)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K17 compound treatment 920766.0 349000.0 0.5 998034.0 388000.0 0.54 0.7329 0.9991 2073389 Maybridge1_007453 CC(C)(CC(=O)O)CC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K18 compound treatment 917310.0 345000.0 0.49 944378.0 334000.0 0.47 0.6765 0.9997 2073390 Maybridge1_007454 CN(C)/N=C/c1ccc(o1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K19 compound treatment 932071.0 360000.0 0.51 995702.0 385000.0 0.54 0.7419 0.9997 2073391 Maybridge1_007455 Ic1ccc(cc1)N2C(=O)COCC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K20 compound treatment 918567.0 346000.0 0.49 958562.0 348000.0 0.49 0.6917 1.0 1391986 Maybridge1_007456 Cc1ccc(cc1)n2c(SCC(=O)C(C)(C)C)nc3ccc(C)cc3c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K21 compound treatment 946943.0 375000.0 0.53 979169.0 369000.0 0.51 0.7406 0.9998 2073392 Maybridge1_007457 NC(=N)SCc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K22 compound treatment 910521.0 338000.0 0.48 938367.0 328000.0 0.46 0.6637 0.9997 1920845 Maybridge1_007458 CCOC(=O)CNc1ccc(I)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K23 mock treatment 981907.0 410000.0 0.58 985485.0 375000.0 0.52 0.782 0.9985 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 K24 mock treatment 165417.0 -407000.0 -0.58 166957.0 -443000.0 -0.62 -0.8463 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L01 compound treatment 776922.0 205000.0 0.29 815022.0 205000.0 0.29 0.4077 0.9999 2073393 Maybridge1_007459 Cc1ccc(OC(=O)c2ccc(cc2)C(F)(F)F)c(NC(=O)c3ccc(cc3)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L02 compound treatment 842795.0 271000.0 0.38 858004.0 248000.0 0.35 0.5164 0.9985 2073394 Maybridge1_007460 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L03 compound treatment 863931.0 292000.0 0.42 984530.0 374000.0 0.52 0.6624 0.9936 2073395 Maybridge1_007461 CC(C)c1ccc(/C=C/2\N=C(OC2=O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L04 compound treatment 877609.0 306000.0 0.43 905254.0 295000.0 0.41 0.598 0.9996 2073396 Maybridge1_007462 Cc1ccc(C)n1c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L05 compound treatment 839994.0 268000.0 0.38 1014219.0 404000.0 0.56 0.6676 0.9819 1293252 Maybridge1_007463 COc1ccccc1CNC(=S)NCCO 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L06 compound treatment 881430.0 309000.0 0.44 904330.0 294000.0 0.41 0.6009 0.9994 1271776 Maybridge1_007464 Clc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L07 compound treatment 880434.0 308000.0 0.44 990702.0 380000.0 0.53 0.6851 0.9955 2073397 Maybridge1_007465 CC1=NN(C(=O)C1=C2SCCS2)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L08 compound treatment 838673.0 267000.0 0.38 962623.0 352000.0 0.49 0.6154 0.9918 2073398 Maybridge1_007466 NC(=S)c1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L09 compound treatment 863120.0 291000.0 0.41 983007.0 373000.0 0.52 0.6601 0.9936 1495976 Maybridge1_007467 Cn1c2NCN(CCO)Cc2c(=O)n(C)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L10 compound treatment 843000.0 271000.0 0.39 926215.0 316000.0 0.44 0.5839 0.9978 2073399 Maybridge1_007468 CCOC(=O)c1cc(C)nn1c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L11 compound treatment 919118.0 347000.0 0.49 989139.0 379000.0 0.53 0.7225 0.9994 1483326 Maybridge1_007469 COc1ccc(cc1)c2nnn(c2N)c3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L12 compound treatment 867446.0 295000.0 0.42 948450.0 338000.0 0.47 0.6304 0.9983 1268448 Maybridge1_007470 O=C(Nc1ccccc1)c2ncoc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L13 compound treatment 889558.0 317000.0 0.45 1001470.0 391000.0 0.55 0.7049 0.9956 2073400 Maybridge1_007471 CC(C)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L14 compound treatment 882356.0 310000.0 0.44 933125.0 323000.0 0.45 0.6302 1.0 2073401 Maybridge1_007472 Fc1ccc2OC/C(=C\c3ccc(Cl)cc3)/C(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L15 compound treatment 935349.0 363000.0 0.52 1014422.0 404000.0 0.56 0.7637 0.9991 2073402 Maybridge1_007473 FC(F)(F)c1ccc(cc1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L16 compound treatment 906870.0 335000.0 0.48 958896.0 348000.0 0.49 0.6803 0.9999 2073403 Maybridge1_007474 Cc1oc(nc1c2ccccc2)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L17 compound treatment 952717.0 381000.0 0.54 983398.0 373000.0 0.52 0.7506 0.9998 2073404 Maybridge1_007475 CC1c2snnc2-c3cc(Cl)ccc3S1(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L18 compound treatment 892948.0 321000.0 0.46 960002.0 350000.0 0.49 0.6674 0.9995 2073405 Maybridge1_007476 Cc1n[nH]cc1c2nsc(Nc3ccccc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L19 compound treatment 911242.0 339000.0 0.48 979676.0 369000.0 0.51 0.7052 0.9995 2073406 Maybridge1_007477 c1snnc1c2nc(no2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L20 compound treatment 887060.0 315000.0 0.45 943779.0 333000.0 0.46 0.6455 0.9998 1345036 Maybridge1_007478 COC(=O)C1=C(C)NC(=C(C1c2ccc(OC)cc2)C(=O)OC)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L21 compound treatment 952820.0 381000.0 0.54 1036839.0 426000.0 0.59 0.8034 0.9989 2073407 Maybridge1_007479 Cc1ccc(cc1)c2cnco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L22 compound treatment 905806.0 334000.0 0.47 1023106.0 413000.0 0.58 0.7426 0.9954 2073408 Maybridge1_007480 N#Cc1ccc(s1)c2ccon2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L23 mock treatment 886553.0 314000.0 0.45 987097.0 377000.0 0.53 0.6877 0.9968 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 L24 mock treatment 175119.0 -397000.0 -0.56 141068.0 -469000.0 -0.65 -0.8621 -0.9973 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M01 compound treatment 807654.0 236000.0 0.34 813828.0 203000.0 0.28 0.4375 0.9966 2073409 Maybridge1_007481 CC(=O)N1C(=O)c2ccc(cc2C1=O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M02 compound treatment 796409.0 224000.0 0.32 830350.0 220000.0 0.31 0.4425 0.9998 2073410 Maybridge1_007482 OC(=O)CS(=O)(=O)/C=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M03 compound treatment 908242.0 336000.0 0.48 910951.0 301000.0 0.42 0.6344 0.9979 2073411 Maybridge1_007483 CC(C)(C)NNC(=S)Nc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M04 compound treatment 882719.0 311000.0 0.44 908524.0 298000.0 0.42 0.6063 0.9995 2073412 Maybridge1_007484 [O-][N+](=O)/C=C/c1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M05 compound treatment 895100.0 323000.0 0.46 895208.0 285000.0 0.4 0.6057 0.9974 2073413 Maybridge1_007485 Clc1ccc(NC(=O)OCCSc2nc3ccccc3s2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M06 compound treatment 889239.0 317000.0 0.45 918577.0 308000.0 0.43 0.6228 0.9997 2073414 Maybridge1_007486 NC(=S)Nc1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M07 compound treatment 926936.0 355000.0 0.5 953724.0 343000.0 0.48 0.6954 0.9997 2073415 Maybridge1_007487 COc1ccc(cc1)C2Oc3ccccc3C=C2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M08 compound treatment 878983.0 307000.0 0.44 886969.0 277000.0 0.39 0.5813 0.9981 2073416 Maybridge1_007488 Clc1ccc(c(Cl)c1)c2nc3ccc(I)cc3c(=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M09 compound treatment 902066.0 330000.0 0.47 883309.0 273000.0 0.38 0.6009 0.9946 1268324 Maybridge1_007489 Clc1ccc(Oc2ccccc2N3C(=O)CCC3=O)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M10 compound treatment 861656.0 290000.0 0.41 895159.0 285000.0 0.4 0.572 0.9998 1089151 Maybridge1_007490 c1ccc(cc1)c2nnc(nc2c3ccccc3)c4ccccn4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M11 compound treatment 944074.0 372000.0 0.53 965463.0 355000.0 0.5 0.7242 0.9995 1067264 Maybridge1_007491 COc1ccc(CC(=O)NN)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M12 compound treatment 895274.0 323000.0 0.46 919573.0 309000.0 0.43 0.6299 0.9995 1034877 Maybridge1_007492 c1ccc(cc1)c2nccnc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M13 compound treatment 928085.0 356000.0 0.51 955858.0 345000.0 0.48 0.6986 0.9997 2073417 Maybridge1_007493 Fc1cccc(Cl)c1/C=C/2\NC(=S)NC2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M14 compound treatment 907261.0 335000.0 0.48 927006.0 317000.0 0.44 0.6493 0.9993 2073418 Maybridge1_007494 OCC12COC(N2C(OC1)c3ccc(cc3)[N+](=O)[O-])c4ccc(cc4)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M15 compound treatment 940349.0 368000.0 0.52 931145.0 321000.0 0.45 0.6866 0.9969 2073419 Maybridge1_007495 OC(=O)COCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M16 compound treatment 890543.0 318000.0 0.45 930876.0 320000.0 0.45 0.6363 1.0 1413903 Maybridge1_007496 Cc1csc2c(=O)n(CCO)c(=O)[nH]c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M17 compound treatment 953536.0 381000.0 0.54 988987.0 379000.0 0.53 0.7569 0.9999 1267085 Maybridge1_007497 COc1ccc(OC)c(NC(=O)CSCC(=O)O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M18 compound treatment 941303.0 369000.0 0.53 957954.0 348000.0 0.48 0.714 0.9992 1066415 Maybridge1_007498 O=C1Nc2ccccc2C31OCCO3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M19 compound treatment 967475.0 395000.0 0.56 977375.0 367000.0 0.51 0.7595 0.9989 2073420 Maybridge1_007499 [O-][N+](=O)/C=C/c1ccsc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M20 compound treatment 905670.0 334000.0 0.47 928575.0 318000.0 0.44 0.6492 0.9994 1255373 Maybridge1_007500 O=C1NC2(CCN(Cc3ccccc3)CC2)Oc4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M21 compound treatment 969894.0 398000.0 0.57 987896.0 377000.0 0.53 0.7723 0.9994 1912573 Maybridge1_007501 NC(=N)SCc1ccccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M22 compound treatment 940882.0 369000.0 0.52 951000.0 341000.0 0.47 0.7067 0.9988 1525218 Maybridge1_007502 CCOC(=O)CNc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M23 mock treatment 960995.0 389000.0 0.55 954799.0 344000.0 0.48 0.7307 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 M24 mock treatment 325585.0 -246000.0 -0.35 718387.0 108000.0 0.15 -0.1414 -0.3706 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N01 compound treatment 810092.0 238000.0 0.34 843457.0 233000.0 0.32 0.4691 0.9998 2073421 Maybridge1_007503 Clc1ccc(OC(=O)c2cc(Cl)cc(Cl)c2)c(NC(=O)c3cc(Cl)cc(Cl)c3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N02 compound treatment 852873.0 281000.0 0.4 908175.0 298000.0 0.42 0.576 0.9998 1603122 Maybridge1_007504 OC(=O)C1CN(C(=O)C1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N03 compound treatment 892057.0 320000.0 0.46 971915.0 361000.0 0.5 0.6783 0.9987 2073422 Maybridge1_007505 Oc1nc(c2cccs2)n(n1)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N04 compound treatment 863583.0 292000.0 0.41 950270.0 340000.0 0.47 0.6283 0.9978 2073423 Maybridge1_007506 Cc1cc(C(=O)C(F)(F)F)c(C)n1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N05 compound treatment 902807.0 331000.0 0.47 985095.0 375000.0 0.52 0.7021 0.9986 2073424 Maybridge1_007507 Cc1ccc(Cn2nn[nH]c2=S)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N06 compound treatment 798913.0 227000.0 0.32 945876.0 335000.0 0.47 0.5589 0.9835 1190115 Maybridge1_007508 Cc1cc(C(=O)O)c(C)n1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N07 compound treatment 795274.0 223000.0 0.32 969866.0 359000.0 0.5 0.5789 0.9757 2073425 Maybridge1_007509 Clc1ccc(/C=C\2/Cc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N08 compound treatment 798866.0 227000.0 0.32 921187.0 311000.0 0.43 0.5345 0.9894 2073426 Maybridge1_007510 COc1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N09 compound treatment 889034.0 317000.0 0.45 970870.0 360000.0 0.5 0.6742 0.9985 2073427 Maybridge1_007511 O=C1/C(=C/c2cccs2)/CCc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N10 compound treatment 876995.0 305000.0 0.43 950851.0 340000.0 0.47 0.6423 0.999 2073428 Maybridge1_007512 CC1Sc2ccc(Cl)cc2-c3nc(N)ncc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N11 compound treatment 908849.0 337000.0 0.48 989566.0 379000.0 0.53 0.7125 0.9988 1348357 Maybridge1_007513 COc1ccc(cc1)c2nnn(c2N)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N12 compound treatment 883972.0 312000.0 0.44 967562.0 357000.0 0.5 0.6658 0.9983 1575425 Maybridge1_007514 OC(=O)c1cnc2SCCn2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N13 compound treatment 871195.0 299000.0 0.43 949877.0 339000.0 0.47 0.6355 0.9986 1083393 Maybridge1_007515 CSc1nsc(SC)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N14 compound treatment 807869.0 236000.0 0.34 903002.0 293000.0 0.41 0.5256 0.9952 2073429 Maybridge1_007516 CC(C)(C)c1ccc(s1)C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N15 compound treatment 930419.0 358000.0 0.51 1024866.0 414000.0 0.58 0.769 0.998 2073430 Maybridge1_007517 NNC(=O)Cn1nnc(n1)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N16 compound treatment 885187.0 313000.0 0.45 948962.0 339000.0 0.47 0.6487 0.9996 2073431 Maybridge1_007518 CCOC(=O)c1c(N)c(sc1Nc2ccccc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N17 compound treatment 925496.0 353000.0 0.5 993168.0 383000.0 0.53 0.7328 0.9995 2073432 Maybridge1_007519 Clc1ccc2c(c1)C(=O)CCS2(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N18 compound treatment 853636.0 282000.0 0.4 977474.0 367000.0 0.51 0.6451 0.9926 2073433 Maybridge1_007520 N/C(=N/OC(=O)c1ccsc1)/COc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N19 compound treatment 930132.0 358000.0 0.51 1015115.0 405000.0 0.56 0.7591 0.9987 2073434 Maybridge1_007521 Cc1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N20 compound treatment 906341.0 334000.0 0.48 969311.0 359000.0 0.5 0.69 0.9997 1631791 Maybridge1_007522 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2ccc(OC)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N21 compound treatment 946034.0 374000.0 0.53 1008204.0 398000.0 0.55 0.7683 0.9998 1614300 Maybridge1_007523 Fc1cccc(Cl)c1C(=O)Nc2ccc(cc2)c3csnn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N22 compound treatment 919172.0 347000.0 0.49 989595.0 379000.0 0.53 0.723 0.9994 2073435 Maybridge1_007524 COC(=O)c1nn(c(O)c1N=Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N23 mock treatment 911569.0 339000.0 0.48 992739.0 382000.0 0.53 0.7184 0.9988 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 N24 mock treatment 733598.0 162000.0 0.23 643067.0 32600.0 0.05 0.1946 0.831 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O01 compound treatment 827703.0 256000.0 0.36 822759.0 212000.0 0.3 0.4664 0.9948 1596156 Maybridge1_007525 Clc1ccc(cc1)N2C(SCC2=O)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O02 compound treatment 815649.0 244000.0 0.35 817984.0 208000.0 0.29 0.4496 0.996 2073436 Maybridge1_007526 OC(=O)CCS/C=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O03 compound treatment 869555.0 297000.0 0.42 893808.0 283000.0 0.4 0.5786 0.9994 2073437 Maybridge1_007527 COc1cccc(NC(=S)NNC(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O04 compound treatment 860290.0 288000.0 0.41 876217.0 266000.0 0.37 0.5519 0.9987 2073438 Maybridge1_007528 CCOc1cc(=O)oc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O05 compound treatment 906664.0 335000.0 0.48 930401.0 320000.0 0.45 0.652 0.9995 1250787 Maybridge1_007529 O=C1CSC(N1Cc2cccs2)c3cccnc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O06 compound treatment 867720.0 296000.0 0.42 881124.0 271000.0 0.38 0.5642 0.9986 2073439 Maybridge1_007530 NC(=O)NCc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O07 compound treatment 917685.0 346000.0 0.49 899301.0 289000.0 0.4 0.6324 0.9951 2073440 Maybridge1_007531 [O-][N+](=O)C1=Cc2ccccc2OC1c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O08 compound treatment 865634.0 294000.0 0.42 887947.0 278000.0 0.39 0.5689 0.9993 2073441 Maybridge1_007532 OC(=O)c1cc(I)ccc1NC(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O09 compound treatment 900619.0 329000.0 0.47 920099.0 310000.0 0.43 0.6358 0.9992 2073442 Maybridge1_007533 CSc1ccccc1NCN2C(=O)c3ccccc3C2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O10 compound treatment 854164.0 282000.0 0.4 878888.0 268000.0 0.37 0.5484 0.9994 2073443 Maybridge1_007534 c1ccc(nc1)c2nnc(c3ccccn3)c(n2)c4ccccn4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O11 compound treatment 926181.0 354000.0 0.5 914566.0 304000.0 0.42 0.656 0.9964 1400974 Maybridge1_007535 COc1ccc(Cc2nnc(S)n2c3ccc(Cl)cc3)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O12 compound treatment 858386.0 286000.0 0.41 862896.0 252000.0 0.35 0.5369 0.9974 1019170 Maybridge1_007536 CC(=O)c1cc2ccccc2o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O13 compound treatment 898548.0 326000.0 0.46 920160.0 310000.0 0.43 0.6337 0.9994 1516762 Maybridge1_007537 COc1cc(cc(OC)c1OC)C(CC(=O)O)CC(=O)Nc2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O14 compound treatment 885252.0 313000.0 0.45 877433.0 267000.0 0.37 0.5782 0.996 2073444 Maybridge1_007538 Cc1cccc(NC2=NC(CO)(CO)CS2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O15 compound treatment 960680.0 389000.0 0.55 892469.0 282000.0 0.39 0.6689 0.9861 1732801 Maybridge1_007539 CCOC(=O)CCn1c(=S)n(CCC(=O)OCC)c2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O16 compound treatment 836081.0 264000.0 0.38 875413.0 265000.0 0.37 0.5268 1.0 2073445 Maybridge1_007540 FC(F)(F)c1ccc(/C=C/2\Cc3ccccc3C2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O17 compound treatment 926091.0 354000.0 0.5 924150.0 314000.0 0.44 0.6654 0.9976 2073446 Maybridge1_007541 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O18 compound treatment 1854888.0 1280000.0 1.82 2021821.0 1410000.0 1.97 2.6819 0.9993 2073447 Maybridge1_007542 COc1cccc(/C=C(\C#N)/C(=O)c2ccc(cc2)C(C)(C)C)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O19 compound treatment 901829.0 330000.0 0.47 951376.0 341000.0 0.48 0.6678 1.0 2073448 Maybridge1_007543 CCOC(=O)C1=C(C)NC(=S)NC1c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O20 compound treatment 902850.0 331000.0 0.47 922781.0 312000.0 0.44 0.6406 0.9993 2073449 Maybridge1_007544 COc1ccc(OC)c(C=C2C(=O)OC(C)(C)OC2=O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O21 compound treatment 936810.0 365000.0 0.52 968738.0 358000.0 0.5 0.7201 0.9998 2073450 Maybridge1_007545 NC(=N)SCc1c(F)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O22 compound treatment 910229.0 338000.0 0.48 886414.0 276000.0 0.38 0.6122 0.9939 1081745 Maybridge1_007546 CCOC(=O)CNc1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O23 mock treatment 939583.0 368000.0 0.52 930885.0 320000.0 0.45 0.6856 0.997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 O24 mock treatment 292571.0 -280000.0 -0.4 548657.0 -61800.0 -0.09 -0.342 -0.8409 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P01 compound treatment 781329.0 209000.0 0.3 812738.0 202000.0 0.28 0.4099 0.9996 2073451 Maybridge1_007547 Cc1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)c(OC(=O)c3ccc(cc3)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P02 compound treatment 811570.0 239000.0 0.34 839679.0 229000.0 0.32 0.4669 0.9995 2073452 Maybridge1_007548 NC(=N)SCc1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P03 compound treatment 804357.0 232000.0 0.33 858202.0 248000.0 0.35 0.4779 0.9997 2073453 Maybridge1_007549 COc1ccc(/N=C/2\SCC(=NN2C)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P04 compound treatment 829687.0 258000.0 0.37 860980.0 251000.0 0.35 0.5061 0.9997 2073454 Maybridge1_007550 N#Cc1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P05 compound treatment 843118.0 271000.0 0.39 873988.0 264000.0 0.37 0.5325 0.9997 1928310 Maybridge1_007551 COc1cccc(/C=C\2/N=C(OC2=O)c3ccc(NC(=O)C)cc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P06 compound treatment 840103.0 268000.0 0.38 861127.0 251000.0 0.35 0.5167 0.9991 2073455 Maybridge1_007552 Cc1cccc(Cl)c1/C=N/NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P07 compound treatment 857486.0 285000.0 0.41 870096.0 260000.0 0.36 0.5431 0.9984 2073456 Maybridge1_007553 O=C1/C(=C/c2ccccn2)/CCc3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P08 compound treatment 827852.0 256000.0 0.36 866979.0 257000.0 0.36 0.5102 1.0 1363727 Maybridge1_007554 NC(=O)c1ccc(cc1)c2csnn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P09 compound treatment 832154.0 260000.0 0.37 848847.0 238000.0 0.33 0.4966 0.9986 2073457 Maybridge1_007555 COc1ccc2C(=O)/C(=C/c3ccc(C)cc3)/CCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P10 compound treatment 865806.0 294000.0 0.42 850507.0 240000.0 0.33 0.5321 0.994 1449237 Maybridge1_007556 Clc1ccc(NC(=O)c2ccc(cc2)c3csnn3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P11 compound treatment 824086.0 252000.0 0.36 835048.0 225000.0 0.31 0.4749 0.9978 2073458 Maybridge1_007557 CS/C(=N/C#N)/Nc1ccc(cc1)C(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P12 compound treatment 847039.0 275000.0 0.39 864906.0 254000.0 0.35 0.5275 0.9988 2073459 Maybridge1_007558 OC(=O)CCOc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P13 compound treatment 835054.0 263000.0 0.37 862249.0 252000.0 0.35 0.5128 0.9995 1108926 Maybridge1_007559 CSc1nsc(SC)c1C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P14 compound treatment 838892.0 267000.0 0.38 856976.0 247000.0 0.34 0.5114 0.9988 2073460 Maybridge1_007560 Cc1cc(oc(=O)c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P15 compound treatment 861449.0 289000.0 0.41 864828.0 254000.0 0.35 0.5419 0.9973 2073461 Maybridge1_007561 N=C(NNC(=O)Nc1ccccc1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P16 compound treatment 871629.0 300000.0 0.43 861126.0 251000.0 0.35 0.5484 0.9952 2073462 Maybridge1_007562 Cc1nc(C)c(o1)c2ccnc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P17 compound treatment 880811.0 309000.0 0.44 891111.0 281000.0 0.39 0.5873 0.9984 1574791 Maybridge1_007563 CCOC(=O)C1CSC(=C(C)N1)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P18 compound treatment 872975.0 301000.0 0.43 899612.0 289000.0 0.4 0.5878 0.9996 1137432 Maybridge1_007564 COC(=O)c1c(C)nc(C)c(C(=O)OC)c1c2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P19 compound treatment 886504.0 314000.0 0.45 884409.0 274000.0 0.38 0.5864 0.9969 2073463 Maybridge1_007565 CC(C)(C)S(=O)(=O)/C(=C/c1ccc(F)cc1F)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P20 compound treatment 842861.0 271000.0 0.39 889288.0 279000.0 0.39 0.5473 1.0 2073464 Maybridge1_007566 FC(F)(F)Oc1ccc(cc1)C2NCCc3sccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P21 compound treatment 838236.0 266000.0 0.38 896188.0 286000.0 0.4 0.5494 0.9997 1381208 Maybridge1_007567 CS(=O)(=O)c1nsc(c1C(=O)N)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P22 compound treatment 849676.0 278000.0 0.39 902124.0 292000.0 0.41 0.5668 0.9999 2073465 Maybridge1_007568 CCOC(=O)c1cnc2ccc(cn2c1=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P23 mock treatment 828940.0 257000.0 0.37 866062.0 256000.0 0.36 0.5104 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.562 P24 mock treatment 289334.0 -283000.0 -0.4 576648.0 -33800.0 -0.05 -0.3176 -0.7846 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A01 compound treatment 769898.0 219000.0 0.31 823671.0 218000.0 0.3 0.4349 0.9999 2073466 Maybridge1_007569 Clc1ccc(OS(=O)(=O)c2ccc(s2)c3ccc(s3)S(=O)(=O)Oc4ccc(Cl)c(Cl)c4)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A02 compound treatment 761440.0 211000.0 0.3 828882.0 223000.0 0.31 0.4315 0.9998 2073467 Maybridge1_007570 COC(=O)c1ccc(CO/N=C(\N)/c2cc(Cl)c(N)c(Cl)c2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A03 compound treatment 752493.0 202000.0 0.29 825940.0 220000.0 0.31 0.4196 0.9994 2073468 Maybridge1_007571 CN(C)S(=O)(=O)Oc1ccc(C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A04 compound treatment 775331.0 224000.0 0.32 834592.0 229000.0 0.32 0.4511 1.0 2073469 Maybridge1_007572 Cc1nn(c(O)c1N=Nc2cccc(c2)C(F)(F)F)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A05 compound treatment 781842.0 231000.0 0.33 856847.0 251000.0 0.35 0.4796 0.9995 2073470 Maybridge1_007573 CC(=O)Nc1ccccc1OCC(O)CNCc2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A06 compound treatment 800515.0 250000.0 0.35 859907.0 254000.0 0.35 0.5014 1.0 1226336 Maybridge1_007574 NNC(=O)Cc1csc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A07 compound treatment 826025.0 275000.0 0.39 880924.0 275000.0 0.38 0.5478 1.0 1488274 Maybridge1_007575 NC(=S)Nc1ccncc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A08 compound treatment 820989.0 270000.0 0.38 886756.0 281000.0 0.39 0.5485 1.0 2073471 Maybridge1_007576 CCOC(=O)c1c(C)nn(c1C)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A09 compound treatment 818269.0 267000.0 0.38 893642.0 288000.0 0.4 0.5526 0.9996 2073472 Maybridge1_007577 NC(=O)c1sc(C#N)c(c1c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A10 compound treatment 799177.0 248000.0 0.35 892073.0 286000.0 0.4 0.5318 0.9981 2073473 Maybridge1_007578 OCCSc1ccc(C#N)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A11 compound treatment 783854.0 233000.0 0.33 876273.0 270000.0 0.38 0.5008 0.9979 2073474 Maybridge1_007579 Fc1ccc(cc1)c2csc(Nc3cccnc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A12 compound treatment 819658.0 269000.0 0.38 891037.0 285000.0 0.4 0.5514 0.9998 1655148 Maybridge1_007580 Fc1cccc(F)c1C(=O)N2CCC(CC2)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A13 compound treatment 821212.0 270000.0 0.38 887367.0 281000.0 0.39 0.5493 0.9999 2073475 Maybridge1_007581 OC(=O)c1c[nH]c2c(c(sc2c1=O)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A14 compound treatment 759225.0 208000.0 0.3 874873.0 269000.0 0.38 0.4747 0.9932 2073476 Maybridge1_007582 CC1(C)C2CCC1(CS(=O)(=O)NCc3ccc(cc3)C(F)(F)F)C(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A15 compound treatment 776598.0 226000.0 0.32 885424.0 279000.0 0.39 0.5025 0.9953 2073477 Maybridge1_007583 Brc1cc(sc1Br)S(=O)(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A16 compound treatment 815511.0 265000.0 0.38 901216.0 295000.0 0.41 0.5572 0.999 2073478 Maybridge1_007584 Cc1ccc(cc1)S(=O)(=O)NC(=O)NNC(=O)c2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A17 compound treatment 835430.0 285000.0 0.4 922772.0 317000.0 0.44 0.5985 0.999 2073479 Maybridge1_007585 Nc1nc(ncc1C#N)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A18 compound treatment 794678.0 244000.0 0.35 885512.0 280000.0 0.39 0.5208 0.9983 1513083 Maybridge1_007586 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A19 compound treatment 822464.0 272000.0 0.39 902546.0 297000.0 0.41 0.5656 0.9994 2073480 Maybridge1_007587 Cc1ccc(C=C2C(=O)OC(C)(C)OC2=O)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A20 compound treatment 798009.0 247000.0 0.35 897715.0 292000.0 0.41 0.5362 0.9973 2073481 Maybridge1_007588 CCOC(=O)c1c(C)nn(c1C)c2ncccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A21 compound treatment 784466.0 234000.0 0.33 881317.0 275000.0 0.38 0.5064 0.9974 2073482 Maybridge1_007589 O=C1CSC(=N1)Cc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A22 compound treatment 783771.0 233000.0 0.33 875333.0 269000.0 0.38 0.4998 0.998 2073483 Maybridge1_007590 COc1ccc2cc(ccc2c1)/C(=N/Oc3ncccc3[N+](=O)[O-])/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A23 mock treatment 764140.0 213000.0 0.3 840439.0 234000.0 0.33 0.4457 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 A24 mock treatment 140533.0 -410000.0 -0.58 143153.0 -463000.0 -0.65 -0.8691 -0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B01 compound treatment 796074.0 245000.0 0.35 802092.0 196000.0 0.27 0.4399 0.9928 2073484 Maybridge1_007591 COc1cc(CC(=O)NN)c(cc1OC)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B02 compound treatment 818490.0 268000.0 0.38 855230.0 249000.0 0.35 0.5149 0.999 2073485 Maybridge1_007592 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2c(Cl)cc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B03 compound treatment 846696.0 296000.0 0.42 941680.0 336000.0 0.47 0.6285 0.9986 2073486 Maybridge1_007593 COC(=O)c1cccn1c2ccccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B04 compound treatment 2269642.0 1720000.0 2.44 2810396.0 2200000.0 3.07 3.9023 0.9935 2073487 Maybridge1_007594 Cc1ccc(N/N=C/2\C(=O)Nc3ccc(F)cc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B05 compound treatment 990245.0 439000.0 0.62 1078412.0 472000.0 0.66 0.9077 0.9996 2073488 Maybridge1_007595 CCOC(=O)c1c(C)nn(c1C)c2ncccc2N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B06 compound treatment 840879.0 290000.0 0.41 913060.0 307000.0 0.43 0.5944 0.9998 2073489 Maybridge1_007596 CC/C(=N\OC(=O)c1cccc(c1)C(F)(F)F)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B07 compound treatment 902091.0 351000.0 0.5 963154.0 357000.0 0.5 0.7054 1.0 2073490 Maybridge1_007597 CC(=O)c1ccc(OCc2cc(F)cc(F)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B08 compound treatment 899527.0 349000.0 0.5 902242.0 296000.0 0.41 0.6427 0.9959 2073491 Maybridge1_007598 Fc1ccccc1c2ccc(cc2)C(=O)Nc3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B09 compound treatment 883236.0 332000.0 0.47 997025.0 391000.0 0.55 0.7198 0.9975 1021442 Maybridge1_007599 OC(C1CCCCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B10 compound treatment 884733.0 334000.0 0.47 980493.0 375000.0 0.52 0.705 0.9989 1194389 Maybridge1_007600 NC(=S)Nc1ccccc1N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B11 compound treatment 902875.0 352000.0 0.5 958876.0 353000.0 0.49 0.702 1.0 2073492 Maybridge1_007601 NC(=S)C1(CC1)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B12 compound treatment 868009.0 317000.0 0.45 964749.0 359000.0 0.5 0.6727 0.9987 1411788 Maybridge1_007602 Cc1sc(Nc2ccccc2N3CCOCC3)nc1c4ccc(cc4)c5ccccc5F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B13 compound treatment 912327.0 361000.0 0.51 1001045.0 395000.0 0.55 0.7531 0.9994 2073493 Maybridge1_007603 CCOC(=O)Nc1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B14 compound treatment 866193.0 315000.0 0.45 985445.0 379000.0 0.53 0.6913 0.9966 2073494 Maybridge1_007604 COc1ccc(/C=N/c2ccc(OC)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B15 compound treatment 825143.0 274000.0 0.39 1014806.0 409000.0 0.57 0.679 0.9828 2073495 Maybridge1_007605 Clc1sc(cc1Br)S(=O)(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B16 compound treatment 871407.0 320000.0 0.46 994960.0 389000.0 0.54 0.7059 0.9962 1351444 Maybridge1_007606 Cc1ccc(c2csc(N)n2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B17 compound treatment 887319.0 336000.0 0.48 996581.0 391000.0 0.54 0.7235 0.9979 2073496 Maybridge1_007607 FC(F)(F)Oc1ccccc1NN=C(C#N)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B18 compound treatment 822310.0 271000.0 0.39 993515.0 388000.0 0.54 0.6551 0.9864 2073497 Maybridge1_007608 CC(C)(NC(=O)c1ccc(cc1)c2ccccc2F)C#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B19 compound treatment 867805.0 317000.0 0.45 993710.0 388000.0 0.54 0.7011 0.9959 2073498 Maybridge1_007609 Cc1csc(n1)c2c(Cl)cc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B20 compound treatment 840842.0 290000.0 0.41 952820.0 347000.0 0.48 0.6336 0.9968 2073499 Maybridge1_007610 COc1cccc(c1)N2C=CC(C)(C)NC2=S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B21 compound treatment 858532.0 308000.0 0.44 993464.0 388000.0 0.54 0.6915 0.9945 1620872 Maybridge1_007611 OC(=O)c1cccn1c2ccccc2C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B22 compound treatment 831494.0 281000.0 0.4 952107.0 346000.0 0.48 0.6235 0.9955 1602815 Maybridge1_007612 COC(=O)c1cc(NC(=O)c2c(C)noc2C)ccc1N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B23 mock treatment 811843.0 261000.0 0.37 928611.0 323000.0 0.45 0.5806 0.9954 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 B24 mock treatment 127154.0 -424000.0 -0.6 156113.0 -450000.0 -0.63 -0.8698 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C01 compound treatment 768355.0 217000.0 0.31 831266.0 225000.0 0.31 0.4408 1.0 2073500 Maybridge1_007613 CN(/N=C/c1ccccc1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C02 compound treatment 804987.0 254000.0 0.36 902066.0 296000.0 0.41 0.5475 0.9978 1201110 Maybridge1_007614 COc1cc(Cl)c(NC(=O)C)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C03 compound treatment 829580.0 279000.0 0.4 977108.0 371000.0 0.52 0.6462 0.9913 2073501 Maybridge1_007615 Cc1cc(cc(C)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C04 compound treatment 996192.0 445000.0 0.63 1096600.0 491000.0 0.68 0.9316 0.9992 2073502 Maybridge1_007616 NC(=N)Sc1cnc2ccccc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C05 compound treatment 867898.0 317000.0 0.45 968116.0 362000.0 0.51 0.6759 0.9984 2073503 Maybridge1_007617 COc1ccc(OS(=O)(=O)c2sc(Br)cc2Br)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C06 compound treatment 820403.0 269000.0 0.38 926722.0 321000.0 0.45 0.5873 0.997 2073504 Maybridge1_007618 [O-][N+](=O)c1cc(cc2c1nc3ccccn32)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C07 compound treatment 851319.0 300000.0 0.43 996191.0 390000.0 0.54 0.6869 0.9928 2073505 Maybridge1_007619 Fc1ccc(cc1)c2cc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C08 compound treatment 871565.0 321000.0 0.46 1013433.0 407000.0 0.57 0.7243 0.994 2073506 Maybridge1_007620 CCOC(=O)c1c(C)nn(c1C)c2ccc(N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C09 compound treatment 890288.0 339000.0 0.48 1033699.0 428000.0 0.6 0.7631 0.9945 1003495 Maybridge1_007621 c1ccc(cc1)c2nnsc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C10 compound treatment 790257.0 239000.0 0.34 996749.0 391000.0 0.55 0.6261 0.9743 2073507 Maybridge1_007622 Fc1ccc(cc1Cl)C(=O)c2ccc(F)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C11 compound treatment 859479.0 309000.0 0.44 989839.0 384000.0 0.54 0.6889 0.9951 2073508 Maybridge1_007623 Brc1cccc(c1)c2csc(Nc3cccnc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C12 compound treatment 858386.0 307000.0 0.44 1037385.0 431000.0 0.6 0.7347 0.9877 1218712 Maybridge1_007624 Cc1onc(c1C(=O)N2CCC(CC2)C(=O)c3ccccc3)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C13 compound treatment 917223.0 366000.0 0.52 1022511.0 417000.0 0.58 0.7791 0.9985 2073509 Maybridge1_007625 CC(=O)c1ccc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C14 compound treatment 872888.0 322000.0 0.46 1024953.0 419000.0 0.58 0.737 0.9927 2073510 Maybridge1_007626 N#CN=C(Oc1ccccc1)Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C15 compound treatment 927755.0 377000.0 0.54 1049551.0 444000.0 0.62 0.8164 0.9974 2073511 Maybridge1_007627 CN(C)S(=O)(=O)c1cc(Br)c(Br)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C16 compound treatment 868562.0 318000.0 0.45 1045111.0 439000.0 0.61 0.7525 0.9888 1282569 Maybridge1_007628 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C17 compound treatment 901561.0 351000.0 0.5 1063328.0 457000.0 0.64 0.8037 0.9926 2073512 Maybridge1_007629 CC(C)(C)c1nc(c2ccc(cc2)C(F)(F)F)c3c(cccc3n1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C18 compound treatment 856528.0 306000.0 0.43 962566.0 357000.0 0.5 0.659 0.9977 2073513 Maybridge1_007630 CCOC(=O)c1cc(C)n(c1c2ccccc2)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C19 compound treatment 865215.0 314000.0 0.45 987167.0 381000.0 0.53 0.692 0.9963 2073514 Maybridge1_007631 FC(F)(F)c1cc(Cl)c(N/N=C/c2cccs2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C20 compound treatment 870912.0 320000.0 0.46 984089.0 378000.0 0.53 0.6947 0.9973 2073515 Maybridge1_007632 OC(=O)/C=C/C(=O)Nc1ccc(cc1)n2nc(cc2C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C21 compound treatment 865332.0 314000.0 0.45 1047138.0 441000.0 0.62 0.7513 0.9877 2073516 Maybridge1_007633 CCNCC(=O)Nc1c(C)cccc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C22 compound treatment 820424.0 270000.0 0.38 988990.0 383000.0 0.53 0.6488 0.9867 2073517 Maybridge1_007634 COCCCNC(=S)N/N=C/c1ccc[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C23 mock treatment 807020.0 256000.0 0.36 1006722.0 401000.0 0.56 0.6528 0.9785 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 C24 mock treatment 146076.0 -405000.0 -0.58 159497.0 -446000.0 -0.62 -0.8474 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D01 compound treatment 788385.0 237000.0 0.34 821890.0 216000.0 0.3 0.4517 0.9984 2073518 Maybridge1_007635 FC(F)(F)c1cc(cc(c1)S(=O)(=O)n2cccc2C(=O)c3ccccc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D02 compound treatment 831445.0 281000.0 0.4 863683.0 258000.0 0.36 0.5363 0.9986 2073519 Maybridge1_007636 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2c(Cl)cc(Cl)cc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D03 compound treatment 852271.0 301000.0 0.43 938632.0 333000.0 0.46 0.6311 0.9992 2073520 Maybridge1_007637 Fc1cc(F)cc(COC(=O)c2c(F)cccc2F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D04 compound treatment 864394.0 313000.0 0.45 944480.0 339000.0 0.47 0.6491 0.9996 2073521 Maybridge1_007638 Fc1ccc2NC(=O)/C(=N\N3CCOCC3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D05 compound treatment 875913.0 325000.0 0.46 970830.0 365000.0 0.51 0.6866 0.9988 2073522 Maybridge1_007639 COC(=O)c1cccn1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D06 compound treatment 864023.0 313000.0 0.45 904296.0 298000.0 0.42 0.6091 0.9994 2073523 Maybridge1_007640 CC/C(=N\OC(=O)c1cccs1)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D07 compound treatment 887873.0 337000.0 0.48 961023.0 355000.0 0.5 0.689 0.9999 2073524 Maybridge1_007641 CC(=O)c1coc2ccccc2c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D08 compound treatment 887580.0 337000.0 0.48 975006.0 369000.0 0.51 0.7025 0.9993 1437052 Maybridge1_007642 Fc1ccccc1c2ccc(cc2)C(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D09 compound treatment 1007100.0 456000.0 0.65 1088795.0 483000.0 0.67 0.9349 0.9998 2073525 Maybridge1_007643 OC(c1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D10 compound treatment 866038.0 315000.0 0.45 1007542.0 402000.0 0.56 0.7129 0.9939 2073526 Maybridge1_007644 NC(=S)Nc1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D11 compound treatment 914843.0 364000.0 0.52 1050419.0 444000.0 0.62 0.8043 0.996 2073527 Maybridge1_007645 COC(=O)c1cc(ccc1N2CCOCC2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D12 compound treatment 865060.0 314000.0 0.45 914532.0 309000.0 0.43 0.6202 0.9998 2073528 Maybridge1_007646 CN(C)/C=C/1\CSc2ccc(F)cc2C1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D13 compound treatment 906103.0 355000.0 0.51 987773.0 382000.0 0.53 0.7337 0.9997 1033621 Maybridge1_007647 CCOC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D14 compound treatment 894685.0 344000.0 0.49 991404.0 385000.0 0.54 0.7258 0.9989 2073529 Maybridge1_007648 N#Cc1cnc2CCCCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D15 compound treatment 878767.0 328000.0 0.47 1023833.0 418000.0 0.58 0.7418 0.9939 2073530 Maybridge1_007649 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2sc(Cl)cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D16 compound treatment 885658.0 335000.0 0.48 1013804.0 408000.0 0.57 0.7388 0.9961 2073531 Maybridge1_007650 Cc1nc(cs1)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D17 compound treatment 916962.0 366000.0 0.52 1020350.0 414000.0 0.58 0.7768 0.9986 2073532 Maybridge1_007651 COC(=O)CCCCCCCC(=O)Nc1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D18 compound treatment 871754.0 321000.0 0.46 981159.0 375000.0 0.52 0.6926 0.9977 2073533 Maybridge1_007652 Cc1ccc(cc1)c2csc(NC(=N)N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D19 compound treatment 911965.0 361000.0 0.51 1038601.0 433000.0 0.6 0.7897 0.9968 2073534 Maybridge1_007653 Cc1ccc(cc1)C(=O)C2CCN(CC2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D20 compound treatment 818047.0 267000.0 0.38 1015126.0 409000.0 0.57 0.6721 0.9804 2073535 Maybridge1_007654 Fc1ccc2c(c1)C(=O)CCS2(=O)=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D21 compound treatment 907090.0 356000.0 0.51 1037708.0 432000.0 0.6 0.7839 0.9963 2073536 Maybridge1_007655 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CC4(CC5CC6CC(C5)C4)C6 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D22 compound treatment 828391.0 277000.0 0.39 929711.0 324000.0 0.45 0.5983 0.9977 2073537 Maybridge1_007656 FC(F)(F)c1cc(Oc2ccc(NS(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D23 mock treatment 863907.0 313000.0 0.45 995576.0 390000.0 0.54 0.699 0.9951 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 D24 mock treatment 143194.0 -408000.0 -0.58 152603.0 -453000.0 -0.63 -0.8571 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E01 compound treatment 792201.0 241000.0 0.34 812507.0 207000.0 0.29 0.4463 0.9962 2073538 Maybridge1_007657 CN(NC(=O)c1ccccc1Cl)c2ncc(Cl)cc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E02 compound treatment 783402.0 232000.0 0.33 838092.0 232000.0 0.32 0.4627 0.9999 1341856 Maybridge1_007658 COc1ccc(Nc2c(Cl)cc(OC)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E03 compound treatment 890173.0 339000.0 0.48 952379.0 346000.0 0.48 0.6828 1.0 2073539 Maybridge1_007659 OC(=O)CSCC(=O)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E04 compound treatment 848929.0 298000.0 0.42 941295.0 335000.0 0.47 0.6304 0.9988 2073540 Maybridge1_007660 FC(F)(F)c1cnc(N2CCNCC2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E05 compound treatment 914600.0 364000.0 0.52 994714.0 389000.0 0.54 0.7491 0.9997 2073541 Maybridge1_007661 C(/N=C/c1cccs1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E06 compound treatment 775898.0 225000.0 0.32 971428.0 365000.0 0.51 0.5867 0.9748 2073542 Maybridge1_007662 CNc1nc(CC(=O)C)ns1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E07 compound treatment 909585.0 359000.0 0.51 985909.0 380000.0 0.53 0.7354 0.9998 2073543 Maybridge1_007663 Fc1ccc(cc1Cl)c2cc3ccccc3[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E08 compound treatment 892254.0 341000.0 0.49 961703.0 356000.0 0.5 0.6941 0.9999 2073544 Maybridge1_007664 Nc1ccc(cc1)n2nc(cc2C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E09 compound treatment 917729.0 367000.0 0.52 1021461.0 416000.0 0.58 0.7786 0.9986 1168457 Maybridge1_007665 COc1ccc(cc1)c2c(C#N)sc(C(=O)N)c2c3ccc(OC)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E10 compound treatment 895532.0 345000.0 0.49 1013240.0 407000.0 0.57 0.7482 0.9973 1033735 Maybridge1_007666 Fc1ccccc1NC(=S)Nc2ccccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E11 compound treatment 901796.0 351000.0 0.5 1043788.0 438000.0 0.61 0.7846 0.995 2073545 Maybridge1_007667 Cc1noc(c1C(=O)O/N=C(\N)/c2cccc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E12 compound treatment 873276.0 322000.0 0.46 993669.0 388000.0 0.54 0.7065 0.9966 2073546 Maybridge1_007668 FC(F)(F)Oc1ccc(cc1)C2CC(=O)Nc3ccccc3S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E13 compound treatment 915180.0 364000.0 0.52 966313.0 360000.0 0.5 0.7217 0.9999 2073547 Maybridge1_007669 Fc1ccc(cc1)/C(=N/OC(=O)c2sc3sccc3c2Cl)/C4CC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E14 compound treatment 847850.0 297000.0 0.42 967736.0 362000.0 0.5 0.6554 0.9961 2073548 Maybridge1_007670 CCOC(=O)c1cc(C)n(N(C)c2cc(ccn2)C(F)(F)F)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E15 compound treatment 911122.0 360000.0 0.51 1054929.0 449000.0 0.63 0.805 0.995 2073549 Maybridge1_007671 CCOC(=O)c1sc(nc1C)c2cnccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E16 compound treatment 916015.0 365000.0 0.52 1023009.0 417000.0 0.58 0.7784 0.9984 2073550 Maybridge1_007672 Cc1ccc(cc1)S(=O)(=O)NC(=O)NNc2c(Cl)cc(Cl)cc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E17 compound treatment 953300.0 402000.0 0.57 1059955.0 454000.0 0.63 0.8524 0.9987 2073551 Maybridge1_007673 N/C(=N\O)/c1cnc(nc1N)c2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E18 compound treatment 892841.0 342000.0 0.49 1021051.0 415000.0 0.58 0.7532 0.9962 2073552 Maybridge1_007674 CCOC(=O)c1cc(C)n(c1c2ccccc2)c3cccc(Cl)c3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E19 compound treatment 894354.0 343000.0 0.49 1031790.0 426000.0 0.59 0.7653 0.9953 2073553 Maybridge1_007675 CS(=O)(=O)c1ccc(s1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E20 compound treatment 888560.0 338000.0 0.48 1020900.0 415000.0 0.58 0.7487 0.9957 2073554 Maybridge1_007676 COc1ccc2cc(ccc2c1)/C(=N/OC(=O)c3cccs3)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E21 compound treatment 908876.0 358000.0 0.51 1047195.0 441000.0 0.62 0.7951 0.9956 2073555 Maybridge1_007677 NS(=O)(=O)c1ccc(s1)c2ccon2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E22 compound treatment 863985.0 313000.0 0.45 987068.0 381000.0 0.53 0.6907 0.9961 1006361 Maybridge1_007678 NNC(=O)c1ccccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E23 mock treatment 821297.0 270000.0 0.38 995617.0 390000.0 0.54 0.6562 0.9856 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 E24 mock treatment 139454.0 -411000.0 -0.59 148632.0 -457000.0 -0.64 -0.8648 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F01 compound treatment 897664.0 347000.0 0.49 919442.0 313000.0 0.44 0.6578 0.9982 2073556 Maybridge1_007679 COc1ccc(cc1)c2ccc(C=C(C#N)C#N)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F02 compound treatment 835625.0 285000.0 0.4 920029.0 314000.0 0.44 0.596 0.9992 2073557 Maybridge1_007680 Fc1ccc2SCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F03 compound treatment 931550.0 381000.0 0.54 917128.0 311000.0 0.43 0.6896 0.994 2073558 Maybridge1_007681 [O-][N+](=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)OCc2cc(F)cc(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F04 compound treatment 885195.0 334000.0 0.48 941138.0 335000.0 0.47 0.6667 1.0 2073559 Maybridge1_007682 CN(/N=C/1\C(=O)Nc2ccc(F)cc12)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F05 compound treatment 992770.0 442000.0 0.63 957336.0 351000.0 0.49 0.7908 0.9924 2073560 Maybridge1_007683 Oc1ccc(/C=N/Nc2ncccc2[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F06 compound treatment 920354.0 369000.0 0.53 976397.0 370000.0 0.52 0.7368 1.0 2073561 Maybridge1_007684 CC/C(=N\OC(=O)CC1(CC2CC3CC(C2)C1)C3)/c4ccc(cc4)c5ccccc5F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F07 compound treatment 878224.0 327000.0 0.47 1041772.0 436000.0 0.61 0.7589 0.9913 2073562 Maybridge1_007685 COc1cc(/C=C/2\COC/C(=C\c3ccc(O)c(OC)c3)/C2=O)ccc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F08 compound treatment 1022534.0 472000.0 0.67 1110163.0 504000.0 0.7 0.9715 0.9997 2073563 Maybridge1_007686 CC/C(=N\Nc1ccc(cc1)[N+](=O)[O-])/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F09 compound treatment 836262.0 285000.0 0.41 963595.0 358000.0 0.5 0.6396 0.9948 2073564 Maybridge1_007687 CC(C)c1ccc(C)c2c(/C=N\Nc3ccc(cc3)[N+](=O)[O-])cc(C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F10 compound treatment 936337.0 385000.0 0.55 1013049.0 407000.0 0.57 0.789 0.9998 2073565 Maybridge1_007688 Cc1sc(Nc2ccc(cc2)C(F)(F)F)nc1c3ccc(cc3)c4ccccc4F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F11 compound treatment 945969.0 395000.0 0.56 1081879.0 476000.0 0.66 0.8666 0.9966 1738910 Maybridge1_007689 COC(=O)c1cc(NC(=O)c2ccco2)ccc1N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F12 compound treatment 907542.0 357000.0 0.51 1024681.0 419000.0 0.58 0.7716 0.9975 2073566 Maybridge1_007690 NC(=S)N/N=C/1\CCSc2ccc(F)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F13 compound treatment 965453.0 415000.0 0.59 989413.0 383000.0 0.53 0.795 0.9988 2073567 Maybridge1_007691 CCOC(=O)Nc1ccsc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F14 compound treatment 927666.0 377000.0 0.54 1000020.0 394000.0 0.55 0.7675 0.9999 2073568 Maybridge1_007692 CC(=O)C/C(=N/c1ccc(cc1)C(F)(F)F)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F15 compound treatment 958695.0 408000.0 0.58 1048116.0 442000.0 0.62 0.8461 0.9995 415 Maybridge1_007693 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F16 compound treatment 939875.0 389000.0 0.55 1004962.0 399000.0 0.56 0.7846 1.0 2073569 Maybridge1_007694 Fc1ccc2SCC/C(=N\OS(=O)(=O)c3ccc(Cl)cc3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F17 compound treatment 916292.0 365000.0 0.52 1002802.0 397000.0 0.55 0.7588 0.9995 2073570 Maybridge1_007695 Clc1cc(Cl)cc(NN=C(C#N)C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F18 compound treatment 893419.0 343000.0 0.49 1047923.0 442000.0 0.62 0.7803 0.9932 2073571 Maybridge1_007696 Cc1ccc(c2csc(NC(=N)N)n2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F19 compound treatment 941064.0 390000.0 0.55 1051781.0 446000.0 0.62 0.832 0.9984 1507272 Maybridge1_007697 Cc1ccc(cc1)C(=O)C2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F20 compound treatment 896146.0 345000.0 0.49 1008111.0 402000.0 0.56 0.7438 0.9978 2073572 Maybridge1_007698 Cc1ccc(c2csc(n2)c3ccccc3)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F21 compound treatment 950636.0 400000.0 0.57 1062053.0 456000.0 0.64 0.8517 0.9984 1275457 Maybridge1_007699 COc1ccc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F22 compound treatment 866810.0 316000.0 0.45 940505.0 335000.0 0.47 0.6476 0.9998 2073573 Maybridge1_007700 FC(F)(F)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F23 mock treatment 916344.0 365000.0 0.52 1000899.0 395000.0 0.55 0.757 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 F24 mock treatment 141497.0 -409000.0 -0.58 158345.0 -448000.0 -0.62 -0.8531 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G01 compound treatment 792233.0 241000.0 0.34 822962.0 217000.0 0.3 0.4567 0.998 2073574 Maybridge1_007701 CCOC(=O)c1c(C)oc2c(F)c(F)c(F)c(F)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G02 compound treatment 796659.0 246000.0 0.35 888945.0 283000.0 0.39 0.5262 0.9982 2073575 Maybridge1_007702 FC(F)(F)c1ccnc(c1)N2CCN(CC2)S(=O)(=O)c3cc(Cl)c(Cl)s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G03 compound treatment 831903.0 281000.0 0.4 876001.0 270000.0 0.38 0.5489 0.9996 2073576 Maybridge1_007703 Cc1nn(C)c(O)c1N=Nc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G04 compound treatment 858912.0 308000.0 0.44 951405.0 345000.0 0.48 0.6504 0.9989 2073577 Maybridge1_007704 c1csc(c1)c2ccc(s2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G05 compound treatment 914669.0 364000.0 0.52 1017211.0 411000.0 0.57 0.7714 0.9987 2073578 Maybridge1_007705 FC(F)(F)c1cccc(N/N=C(\C#N)/C(=O)c2ccsc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G06 compound treatment 920915.0 370000.0 0.53 952906.0 347000.0 0.48 0.7142 0.9991 2073579 Maybridge1_007706 COC(=O)c1cc(Br)cc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G07 compound treatment 948198.0 397000.0 0.56 990194.0 384000.0 0.54 0.7784 0.9997 2073580 Maybridge1_007707 CSc1sccc1/C=C(/C#N)\S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G08 compound treatment 909568.0 359000.0 0.51 971984.0 366000.0 0.51 0.7216 1.0 1579600 Maybridge1_007708 O=C1CC(Sc2ccccc2N1)c3ccsc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G09 compound treatment 903154.0 352000.0 0.5 984330.0 378000.0 0.53 0.7273 0.9997 2073581 Maybridge1_007709 O/N=C/c1c([nH]c2ccccc12)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G10 compound treatment 882123.0 331000.0 0.47 954384.0 348000.0 0.49 0.6767 0.9999 2073582 Maybridge1_007710 Fc1ccccc1NC(=S)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G11 compound treatment 904440.0 354000.0 0.5 1007310.0 401000.0 0.56 0.7513 0.9986 2073583 Maybridge1_007711 Cc1noc(c1c2nc(no2)c3ccc(Cl)cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G12 compound treatment 847082.0 296000.0 0.42 910289.0 304000.0 0.42 0.5979 1.0 2073584 Maybridge1_007712 [O-][N+](=O)c1cc(ccc1N2CCC(CC2)C(=O)c3ccccc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G13 compound treatment 912439.0 362000.0 0.51 994856.0 389000.0 0.54 0.7471 0.9996 1092357 Maybridge1_007713 NC(=S)c1cncnc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G14 compound treatment 894728.0 344000.0 0.49 995759.0 390000.0 0.54 0.7301 0.9986 2073585 Maybridge1_007714 CCSc1ccc(C#N)cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G15 compound treatment 849863.0 299000.0 0.43 1016515.0 411000.0 0.57 0.7055 0.9893 2073586 Maybridge1_007715 N/C(=N\O)/c1cncnc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G16 compound treatment 903636.0 353000.0 0.5 1009385.0 403000.0 0.56 0.7525 0.9984 2073587 Maybridge1_007716 CCSc1ccc(cn1)c2noc(n2)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G17 compound treatment 925434.0 375000.0 0.53 1026043.0 420000.0 0.59 0.7909 0.9989 1983516 Maybridge1_007717 CSc1ccc(s1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G18 compound treatment 909097.0 358000.0 0.51 1008805.0 403000.0 0.56 0.7575 0.9988 2073588 Maybridge1_007718 COc1ccc(OC)c(NS(=O)(=O)c2cc(ccc2OCC(F)(F)F)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G19 compound treatment 933224.0 382000.0 0.54 1021213.0 415000.0 0.58 0.794 0.9995 2073589 Maybridge1_007719 OC(=O)CCC(=O)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G20 compound treatment 883763.0 333000.0 0.47 964758.0 359000.0 0.5 0.6885 0.9996 2073590 Maybridge1_007720 COc1ccc2cc(ccc2c1)/C(=N/OC(=O)Nc3ccc(OC(F)(F)F)cc3)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G21 compound treatment 850717.0 300000.0 0.43 1021066.0 415000.0 0.58 0.7108 0.9887 2073591 Maybridge1_007721 COc1ccc(cc1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G22 compound treatment 1296313.0 745000.0 1.06 1896153.0 1290000.0 1.8 2.0219 0.9682 2073592 Maybridge1_007722 Oc1cc2cc(O)[nH]c(=O)c2c(=O)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G23 mock treatment 883115.0 332000.0 0.47 987056.0 381000.0 0.53 0.7099 0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 G24 mock treatment 138302.0 -413000.0 -0.59 158376.0 -448000.0 -0.62 -0.8563 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H01 compound treatment 826244.0 275000.0 0.39 844734.0 239000.0 0.33 0.5123 0.9968 2073593 Maybridge1_007723 COC(=O)c1cccn1c2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H02 compound treatment 794110.0 243000.0 0.35 845496.0 240000.0 0.33 0.4808 0.9999 2073594 Maybridge1_007724 FC(F)(F)c1ccc(Cl)c(c1)c2ccc(C=C(C#N)C#N)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H03 compound treatment 865712.0 315000.0 0.45 921935.0 316000.0 0.44 0.6282 1.0 2073595 Maybridge1_007725 NC(=O)N/N=C/c1cc(F)cc(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H04 compound treatment 866777.0 316000.0 0.45 969477.0 364000.0 0.51 0.6761 0.9982 2073596 Maybridge1_007726 Fc1ccc2NC(=O)/C(=N\CC3CC3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H05 compound treatment 860550.0 310000.0 0.44 986855.0 381000.0 0.53 0.687 0.9957 2073597 Maybridge1_007727 COc1cccc(/C=N/Nc2ncccc2[N+](=O)[O-])c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H06 compound treatment 896671.0 346000.0 0.49 965221.0 359000.0 0.5 0.702 1.0 2073598 Maybridge1_007728 CC/C(=N\OC(=O)Nc1ccc(OC(F)(F)F)cc1)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H07 compound treatment 939069.0 388000.0 0.55 1007899.0 402000.0 0.56 0.7867 1.0 2073599 Maybridge1_007729 CCOC(=O)c1c(C)nn(c1C)c2ncccc2NC(=S)NC(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H08 compound treatment 949261.0 398000.0 0.57 1005423.0 399000.0 0.56 0.7945 1.0 2073600 Maybridge1_007730 Cc1sc(Nc2ccccc2)nc1c3ccc(cc3)c4ccccc4F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H09 compound treatment 919627.0 369000.0 0.52 1060921.0 455000.0 0.63 0.8194 0.9955 2073601 Maybridge1_007731 N/C(=N\O)/c1cnn2c(ccnc12)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H10 compound treatment 871046.0 320000.0 0.46 917817.0 312000.0 0.43 0.6295 0.9997 1287144 Maybridge1_007732 Cc1sc(nc1c2ccc(cc2)c3ccccc3F)N4CCOCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H11 compound treatment 895706.0 345000.0 0.49 1062698.0 457000.0 0.64 0.7971 0.9916 2073602 Maybridge1_007733 NC(=S)c1cnn2c(ccnc12)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H12 compound treatment 852053.0 301000.0 0.43 991404.0 385000.0 0.54 0.6829 0.9937 2073603 Maybridge1_007734 O/N=C\c1c2ccccc2c(Sc3ccc(Cl)cc3)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H13 compound treatment 871667.0 321000.0 0.46 993863.0 388000.0 0.54 0.7051 0.9964 2073604 Maybridge1_007735 CN(C)c1ccc(C=C(C#N)C#N)c(F)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H14 compound treatment 891900.0 341000.0 0.48 952078.0 346000.0 0.48 0.6842 1.0 1025801 Maybridge1_007736 CC(=O)Nc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H15 compound treatment 868290.0 317000.0 0.45 1042831.0 437000.0 0.61 0.75 0.9891 2073605 Maybridge1_007737 COC(=O)CCCCCCCC(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H16 compound treatment 892395.0 341000.0 0.49 1021461.0 416000.0 0.58 0.7531 0.9961 2073606 Maybridge1_007738 Fc1cc(F)c2OCCC(=O)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H17 compound treatment 913485.0 363000.0 0.52 1045494.0 440000.0 0.61 0.7981 0.9963 2073607 Maybridge1_007739 COC(=O)CCCCCCCC(=O)Nc1ccc(OC)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H18 compound treatment 890732.0 340000.0 0.48 1006796.0 401000.0 0.56 0.737 0.9974 2073608 Maybridge1_007740 OC(=O)C(Cc1ccccc1)NCCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H19 compound treatment 888806.0 338000.0 0.48 1037342.0 431000.0 0.6 0.7652 0.9938 1337126 Maybridge1_007741 Cc1noc(C)c1S(=O)(=O)N2CCC(CC2)C(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H20 compound treatment 872716.0 322000.0 0.46 1010411.0 404000.0 0.56 0.7225 0.9946 2073609 Maybridge1_007742 FC(F)(F)Oc1ccc(cc1)C(=O)Nc2ccc(cc2)n3nc(cc3C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H21 compound treatment 858958.0 308000.0 0.44 1035195.0 429000.0 0.6 0.7331 0.9882 1449635 Maybridge1_007743 Clc1cccc(CNC(=O)CC2(CC3CC4CC(C3)C2)C4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H22 compound treatment 880329.0 329000.0 0.47 940038.0 334000.0 0.47 0.6607 1.0 2073610 Maybridge1_007744 FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(Oc3cc(cc(c3)C(F)(F)F)C(F)(F)F)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H23 mock treatment 889132.0 338000.0 0.48 992281.0 386000.0 0.54 0.7211 0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 H24 mock treatment 147480.0 -403000.0 -0.57 173066.0 -433000.0 -0.6 -0.8326 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I01 compound treatment 813362.0 262000.0 0.37 819255.0 213000.0 0.3 0.4743 0.9937 1379773 Maybridge1_007745 OC(=O)c1coc2CCCC(=O)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I02 compound treatment 856854.0 306000.0 0.44 892939.0 287000.0 0.4 0.5907 0.9991 2073611 Maybridge1_007746 Cc1cc(cc(c1)/C(=N/O)/N)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I03 compound treatment 856885.0 306000.0 0.44 896346.0 290000.0 0.41 0.5941 0.9994 2073612 Maybridge1_007747 Cc1nn(C)c(O)c1N=Nc2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I04 compound treatment 881149.0 330000.0 0.47 919118.0 313000.0 0.44 0.6409 0.9993 2073613 Maybridge1_007748 CC(=O)c1sc(nc1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I05 compound treatment 910984.0 360000.0 0.51 967155.0 361000.0 0.5 0.7183 1.0 2073614 Maybridge1_007749 Brc1ccsc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I06 compound treatment 909277.0 358000.0 0.51 936447.0 330000.0 0.46 0.6863 0.9987 2073615 Maybridge1_007750 NC(=O)c1cc(Br)cc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I07 compound treatment 940862.0 390000.0 0.55 948879.0 343000.0 0.48 0.7303 0.9973 2073616 Maybridge1_007751 CC(CCc1ccccc1)C/C=N/Nc2ccc(cc2[N+](=O)[O-])[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I08 compound treatment 942001.0 391000.0 0.56 970149.0 364000.0 0.51 0.7524 0.999 1060484 Maybridge1_007752 Cc1ccc(cc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I09 compound treatment 962635.0 412000.0 0.59 1061178.0 455000.0 0.63 0.8629 0.9992 2073617 Maybridge1_007753 NC(=S)N/N=C/c1cc2COc3ccc(Cl)cc3-c2s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I10 compound treatment 870747.0 320000.0 0.45 977791.0 372000.0 0.52 0.6883 0.9979 1320459 Maybridge1_007754 OC(=O)C1CCCN1C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I11 compound treatment 926695.0 376000.0 0.53 967174.0 361000.0 0.5 0.7341 0.9996 2073618 Maybridge1_007755 COC(=O)c1csc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I12 compound treatment 926029.0 375000.0 0.53 941671.0 336000.0 0.47 0.7083 0.9979 2073619 Maybridge1_007756 COC(=O)C(=NNc1ccc(cc1)n2nc(C)cc2C)C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I13 compound treatment 932098.0 381000.0 0.54 1003437.0 397000.0 0.55 0.7753 0.9999 2073620 Maybridge1_007757 Clc1cccc(c1)C2CC(=O)CC(=O)C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I14 compound treatment 957241.0 406000.0 0.58 983347.0 377000.0 0.53 0.7808 0.9989 2073621 Maybridge1_007758 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2ccc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I15 compound treatment 913561.0 363000.0 0.52 980244.0 374000.0 0.52 0.7338 1.0 2073622 Maybridge1_007759 NC(=S)c1sccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I16 compound treatment 892882.0 342000.0 0.49 1009872.0 404000.0 0.56 0.7422 0.9973 2073623 Maybridge1_007760 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2ccc(cn2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I17 compound treatment 932171.0 381000.0 0.54 1021375.0 415000.0 0.58 0.7931 0.9995 2073624 Maybridge1_007761 O=S(=O)(CC#N)c1ccsc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I18 compound treatment 895308.0 344000.0 0.49 951506.0 346000.0 0.48 0.6871 1.0 2073625 Maybridge1_007762 CC(C)(C)c1ccc(cc1)C(=O)c2ccc3CCCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I19 compound treatment 909432.0 359000.0 0.51 981727.0 376000.0 0.52 0.7311 0.9999 2073626 Maybridge1_007763 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)CSc4ccc(cn4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I20 compound treatment 934191.0 383000.0 0.55 989597.0 384000.0 0.54 0.7638 1.0 2073627 Maybridge1_007764 COc1ccc2cc(ccc2c1)/C(=N/OC(=O)Nc3ccccc3)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I21 compound treatment 952473.0 402000.0 0.57 1006512.0 401000.0 0.56 0.7988 0.9999 2073628 Maybridge1_007765 CCOc1cc(cnc1C#N)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I22 compound treatment 851257.0 300000.0 0.43 963430.0 357000.0 0.5 0.6546 0.997 2073629 Maybridge1_007766 Fc1cccc(Cl)c1C/N=C/c2c(F)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I23 mock treatment 934254.0 383000.0 0.55 1000153.0 394000.0 0.55 0.7742 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 I24 mock treatment 137998.0 -413000.0 -0.59 143174.0 -463000.0 -0.65 -0.8716 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J01 compound treatment 828100.0 277000.0 0.39 840805.0 235000.0 0.33 0.5103 0.9958 2073630 Maybridge1_007767 FC(F)(F)c1ccc(NC2OC(=O)c3ccccc23)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J02 compound treatment 823890.0 273000.0 0.39 898775.0 293000.0 0.41 0.5633 0.9997 2073631 Maybridge1_007768 FC(F)(F)Oc1ccccc1c2ccc(C=C3C(=O)c4ccccc4C3=O)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J03 compound treatment 913744.0 363000.0 0.52 913899.0 308000.0 0.43 0.6685 0.9958 2073632 Maybridge1_007769 NC(=S)N/N=C/c1cc(F)cc(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J04 compound treatment 872983.0 322000.0 0.46 924079.0 318000.0 0.44 0.6376 0.9999 2073633 Maybridge1_007770 Fc1ccc2NC(=O)/C(=N\c3ccc(Cl)cc3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J05 compound treatment 919320.0 368000.0 0.52 976525.0 371000.0 0.52 0.7359 1.0 2073634 Maybridge1_007771 Cc1cc(C)n(n1)c2ncccc2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J06 compound treatment 896954.0 346000.0 0.49 960918.0 355000.0 0.5 0.698 1.0 2073635 Maybridge1_007772 CC/C(=N\OC(=O)NS(=O)(=O)c1ccc(C)cc1)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J07 compound treatment 938597.0 388000.0 0.55 1008215.0 402000.0 0.56 0.7865 1.0 1678399 Maybridge1_007773 Cc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J08 compound treatment 904651.0 354000.0 0.5 984472.0 379000.0 0.53 0.729 0.9997 2073636 Maybridge1_007774 Cc1ccc(C)n1c2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J09 compound treatment 911251.0 360000.0 0.51 998674.0 393000.0 0.55 0.7496 0.9994 2073637 Maybridge1_007775 CC(C)c1ccc(C)c2c(N=Nc3ccc(Cl)cc3)cc(C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J10 compound treatment 909003.0 358000.0 0.51 966816.0 361000.0 0.5 0.716 1.0 2073638 Maybridge1_007776 Cc1sc(nc1c2ccc(cc2)c3ccccc3F)c4ccsc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J11 compound treatment 934627.0 384000.0 0.55 1020317.0 414000.0 0.58 0.7945 0.9996 2073639 Maybridge1_007777 FC(F)(F)c1cccc(c1)c2ccnc3cc(nn23)c4nc(cs4)c5ccc(Cl)cc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J12 compound treatment 946432.0 396000.0 0.56 992607.0 387000.0 0.54 0.779 0.9998 1365785 Maybridge1_007778 COC(=O)Cc1nc(Nc2ccccc2)sc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J13 compound treatment 882413.0 331000.0 0.47 1009913.0 404000.0 0.56 0.7317 0.9961 2073640 Maybridge1_007779 Clc1sc(cc1Br)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J14 compound treatment 826159.0 275000.0 0.39 987682.0 382000.0 0.53 0.6532 0.9886 1597624 Maybridge1_007780 CCOc1ccc(CCCC(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J15 compound treatment 937182.0 386000.0 0.55 999532.0 394000.0 0.55 0.7766 1.0 1715742 Maybridge1_007781 COc1ccc(CNCc2ccc(OC)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J16 compound treatment 923938.0 373000.0 0.53 1028150.0 422000.0 0.59 0.7915 0.9986 2073641 Maybridge1_007782 Cc1nnsc1C(=O)O/N=C/2\CCSc3ccc(F)cc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J17 compound treatment 944378.0 393000.0 0.56 1014177.0 408000.0 0.57 0.7982 1.0 2073642 Maybridge1_007783 COc1ccc(CN(Cc2ccc(OC)cc2)C(=O)Nc3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J18 compound treatment 900351.0 349000.0 0.5 997941.0 392000.0 0.55 0.738 0.9989 2073643 Maybridge1_007784 Cc1ccc(cc1)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J19 compound treatment 915181.0 364000.0 0.52 991455.0 385000.0 0.54 0.7465 0.9998 1570246 Maybridge1_007785 Clc1ccc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J20 compound treatment 864674.0 314000.0 0.45 990184.0 384000.0 0.54 0.6944 0.9959 2073644 Maybridge1_007786 FC(F)(F)c1cc(n(n1)c2ccc(NC(=O)Nc3cc(Cl)cc(Cl)c3)cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J21 compound treatment 851949.0 301000.0 0.43 1041594.0 436000.0 0.61 0.7323 0.9853 2073645 Maybridge1_007787 CCOC(=O)Cc1nn[nH]n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J22 compound treatment 842316.0 291000.0 0.41 949906.0 344000.0 0.48 0.6322 0.9973 2073646 Maybridge1_007788 FC(F)(F)c1cc(Oc2ccc(NC(=S)NC(=O)c3ccccc3)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J23 mock treatment 807403.0 256000.0 0.36 1009186.0 403000.0 0.56 0.6556 0.978 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 J24 mock treatment 140387.0 -411000.0 -0.58 134593.0 -471000.0 -0.66 -0.8777 -0.9982 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K01 compound treatment 823917.0 273000.0 0.39 807451.0 201000.0 0.28 0.4732 0.9874 2073647 Maybridge1_007789 CN(/N=C/1\CCCc2occ(C(=O)O)c12)c3ncc(Cl)cc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K02 compound treatment 834751.0 284000.0 0.4 839716.0 234000.0 0.33 0.5159 0.9944 2073648 Maybridge1_007790 [O-][N+](=O)c1cccnc1ON=C(c2cccs2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K03 compound treatment 878551.0 328000.0 0.47 858631.0 253000.0 0.35 0.5786 0.9905 2073649 Maybridge1_007791 Cc1nn(C)c(O)c1N=Nc2ccccc2OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K04 compound treatment 919144.0 368000.0 0.52 904558.0 299000.0 0.42 0.6648 0.9936 2073650 Maybridge1_007792 COc1cc(CCC(=O)NNC(=O)c2ccc(Cl)cc2)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K05 compound treatment 893469.0 343000.0 0.49 966545.0 361000.0 0.5 0.7001 0.9999 2073651 Maybridge1_007793 CCOC(=O)c1ccc(COC(=O)C)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K06 compound treatment 895150.0 344000.0 0.49 944443.0 338000.0 0.47 0.68 0.9998 2073652 Maybridge1_007794 Brc1cc(Br)cc(C#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K07 compound treatment 837436.0 287000.0 0.41 992372.0 386000.0 0.54 0.6692 0.9905 2073653 Maybridge1_007795 COc1ccc(cc1)C2=C(C(=O)C)C(=NC(=S)C2C#N)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K08 compound treatment 936948.0 386000.0 0.55 951581.0 346000.0 0.48 0.729 0.9979 2073654 Maybridge1_007796 Fc1ccc(NC(=O)C2CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K09 compound treatment 970850.0 420000.0 0.6 990631.0 385000.0 0.54 0.8016 0.9986 2073655 Maybridge1_007797 CC(=O)Nc1ccc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K10 compound treatment 908259.0 357000.0 0.51 961186.0 355000.0 0.5 0.7097 0.9999 1014540 Maybridge1_007798 O=C(C1CCNCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K11 compound treatment 940048.0 389000.0 0.55 957782.0 352000.0 0.49 0.7383 0.9982 2073656 Maybridge1_007799 Nc1csc2cc(cc(Cl)c12)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K12 compound treatment 903204.0 352000.0 0.5 979152.0 373000.0 0.52 0.7223 0.9998 2073657 Maybridge1_007800 COc1cc(Cl)c(NC(=O)c2cccc(c2)C(F)(F)F)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K13 compound treatment 948768.0 398000.0 0.57 964548.0 359000.0 0.5 0.7537 0.9981 2073658 Maybridge1_007801 COc1ccc(cc1)c2cc[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K14 compound treatment 865465.0 315000.0 0.45 964546.0 359000.0 0.5 0.6699 0.9985 2073659 Maybridge1_007802 Cc1ccc(cc1)S(=O)(=O)NC(=O)O/N=C(\N)/c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K15 compound treatment 943418.0 393000.0 0.56 949000.0 343000.0 0.48 0.733 0.9971 2073660 Maybridge1_007803 CC(C)(C)C(=O)Nc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K16 compound treatment 896489.0 346000.0 0.49 942544.0 337000.0 0.47 0.6794 0.9997 1275090 Maybridge1_007804 COC(=O)c1sccc1NC(=O)NS(=O)(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K17 compound treatment 935231.0 384000.0 0.55 989170.0 383000.0 0.53 0.7644 0.9999 2073661 Maybridge1_007805 CC(=O)C(N=Nc1ccc2OCOCc2c1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K18 compound treatment 854958.0 304000.0 0.43 948842.0 343000.0 0.48 0.6439 0.9987 2073662 Maybridge1_007806 O=C(C1CCC1)c2ccc3CCCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K19 compound treatment 940506.0 390000.0 0.55 1012231.0 406000.0 0.57 0.7924 0.9999 2073663 Maybridge1_007807 COc1ccc(OC)c(SCC(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K20 compound treatment 899352.0 348000.0 0.5 914221.0 308000.0 0.43 0.6544 0.9975 2073664 Maybridge1_007808 COc1ccc2cc(ccc2c1)/C(=N/OC(=O)Nc3cc(Cl)cc(Cl)c3)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K21 compound treatment 918576.0 368000.0 0.52 990875.0 385000.0 0.54 0.7493 0.9999 2073665 Maybridge1_007809 FC(F)(F)c1cnc(C#N)c(Oc2ccc(Cl)cc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K22 compound treatment 865643.0 315000.0 0.45 958666.0 353000.0 0.49 0.6643 0.9989 2073666 Maybridge1_007810 [O-][N+](=O)c1cc(ccc1Oc2ccc(cc2)c3nnco3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K23 mock treatment 926447.0 376000.0 0.53 987300.0 381000.0 0.53 0.7537 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 K24 mock treatment 151838.0 -399000.0 -0.57 136793.0 -469000.0 -0.65 -0.864 -0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L01 compound treatment 800190.0 249000.0 0.35 816849.0 211000.0 0.29 0.4586 0.9957 2073667 Maybridge1_007811 Cc1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L02 compound treatment 819192.0 268000.0 0.38 878863.0 273000.0 0.38 0.5389 1.0 2073668 Maybridge1_007812 CC(=O)c1ccc(o1)c2cc(ccc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L03 compound treatment 904729.0 354000.0 0.5 919303.0 313000.0 0.44 0.6648 0.9975 2073669 Maybridge1_007813 FC(F)(F)C1OC(=O)C(=N1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L04 compound treatment 855011.0 304000.0 0.43 915511.0 310000.0 0.43 0.6111 1.0 2073670 Maybridge1_007814 NC(=S)N/N=C/1\C(=O)Nc2ccc(F)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L05 compound treatment 921161.0 370000.0 0.53 945163.0 339000.0 0.47 0.7068 0.9986 2073671 Maybridge1_007815 Fc1cc(F)cc(Cc2nc(no2)c3cccs3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L06 compound treatment 872155.0 321000.0 0.46 930707.0 325000.0 0.45 0.6433 1.0 1274013 Maybridge1_007816 OC1C(=O)Nc2ccc(F)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L07 compound treatment 919775.0 369000.0 0.52 976012.0 370000.0 0.52 0.7359 1.0 1653929 Maybridge1_007817 Cc1ccc(cc1)C(=O)C2CCN(CC2)C(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L08 compound treatment 902192.0 351000.0 0.5 910547.0 305000.0 0.42 0.6536 0.9967 2073672 Maybridge1_007818 CC/C(=N\OC(=O)Nc1ccccc1)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L09 compound treatment 834469.0 284000.0 0.4 931416.0 325000.0 0.45 0.6061 0.9983 2073673 Maybridge1_007819 CC(C)c1ccc(C)c2c(N=Nc3ccc(cc3)C(F)(F)F)cc(C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L10 compound treatment 889796.0 339000.0 0.48 941707.0 336000.0 0.47 0.6719 0.9999 2073674 Maybridge1_007820 COC(=O)c1cc(C)c(s1)c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L11 compound treatment 919827.0 369000.0 0.52 999511.0 394000.0 0.55 0.7591 0.9997 2073675 Maybridge1_007821 CC(C)(C)c1csc(n1)c2cc3nccc(c4cccc(c4)C(F)(F)F)n3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L12 compound treatment 795615.0 245000.0 0.35 909080.0 303000.0 0.42 0.545 0.9953 2073676 Maybridge1_007822 CCOC(=O)c1cc(C)n(c1C)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L13 compound treatment 925718.0 375000.0 0.53 987844.0 382000.0 0.53 0.7535 1.0 2073677 Maybridge1_007823 CC1CN(CC(C)O1)S(=O)(=O)c2sc(Cl)cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L14 compound treatment 836160.0 285000.0 0.41 920267.0 314000.0 0.44 0.5968 0.9992 1122416 Maybridge1_007824 N#CC(=Cc1ccccc1N2CCN(Cc3ccccc3)CC2)C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L15 compound treatment 934434.0 384000.0 0.55 966487.0 361000.0 0.5 0.7412 0.9992 2073678 Maybridge1_007825 COc1ccc(C/N=C/c2cc(OC)c(OC)c(OC)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L16 compound treatment 893849.0 343000.0 0.49 968970.0 363000.0 0.51 0.7028 0.9998 1454417 Maybridge1_007826 Fc1ccccc1c2ccc(cc2)C(=O)N3CCCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L17 compound treatment 886528.0 336000.0 0.48 970352.0 364000.0 0.51 0.6968 0.9995 1213439 Maybridge1_007827 COc1ccc(CN(Cc2ccc(OC)cc2)C(=O)c3cccs3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L18 compound treatment 852949.0 302000.0 0.43 968241.0 362000.0 0.51 0.661 0.9967 2073679 Maybridge1_007828 Cc1ccc(c2csc(n2)c3ccc(Cl)cc3)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L19 compound treatment 898874.0 348000.0 0.49 993567.0 388000.0 0.54 0.7322 0.999 2073680 Maybridge1_007829 FC(F)(F)c1ccc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L20 compound treatment 891381.0 340000.0 0.48 965840.0 360000.0 0.5 0.6973 0.9998 2073681 Maybridge1_007830 CCCNC(=O)Nc1ccc(cc1)n2nc(cc2C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L21 compound treatment 932810.0 382000.0 0.54 1055482.0 450000.0 0.63 0.8273 0.9974 1530096 Maybridge1_007831 COc1ccc(CNC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L22 compound treatment 867828.0 317000.0 0.45 996437.0 390000.0 0.54 0.7038 0.9956 1616864 Maybridge1_007832 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCSCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L23 mock treatment 857836.0 307000.0 0.44 983138.0 377000.0 0.53 0.6806 0.9957 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 L24 mock treatment 132497.0 -418000.0 -0.6 163845.0 -442000.0 -0.62 -0.8568 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M01 compound treatment 795241.0 244000.0 0.35 747240.0 141000.0 0.2 0.385 0.9639 2073682 Maybridge1_007833 CSc1ccc(N=Nc2c(C)nn(C)c2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M02 compound treatment 842654.0 292000.0 0.41 881624.0 276000.0 0.38 0.5652 0.9993 1581490 Maybridge1_007834 COc1ccc(cc1)C(=O)C2CCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M03 compound treatment 894180.0 343000.0 0.49 916283.0 310000.0 0.43 0.6512 0.9982 1025611 Maybridge1_007835 O=C(c1cccs1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M04 compound treatment 918123.0 367000.0 0.52 900753.0 295000.0 0.41 0.66 0.993 1419896 Maybridge1_007836 Cc1nc(sc1C(=O)NN)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M05 compound treatment 972855.0 422000.0 0.6 937949.0 332000.0 0.46 0.7517 0.9918 1172986 Maybridge1_007837 N#Cc1c(nsc1c2ccccc2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M06 compound treatment 891678.0 341000.0 0.48 922931.0 317000.0 0.44 0.6553 0.9989 2073683 Maybridge1_007838 CCOC(=O)c1c(C)n[nH]c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M07 compound treatment 905984.0 355000.0 0.5 902378.0 296000.0 0.41 0.6494 0.9951 2073684 Maybridge1_007839 CC(=O)c1cc(c(s1)C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M08 compound treatment 895091.0 344000.0 0.49 886243.0 280000.0 0.39 0.6225 0.9938 2073685 Maybridge1_007840 NNC(=S)NC1CC2CC1C=C2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M09 compound treatment 822920.0 272000.0 0.39 901089.0 295000.0 0.41 0.5646 0.9995 1577926 Maybridge1_007841 Clc1cccc(c1)c2csc(Nc3cccnc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M10 compound treatment 924088.0 373000.0 0.53 919678.0 314000.0 0.44 0.6846 0.9954 2073686 Maybridge1_007842 Cc1cc(cc(C)n1)c2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M11 compound treatment 966981.0 416000.0 0.59 956124.0 350000.0 0.49 0.7637 0.9955 1062972 Maybridge1_007843 COC(=O)c1nccnc1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M12 compound treatment 930275.0 379000.0 0.54 921653.0 316000.0 0.44 0.6928 0.9949 2073687 Maybridge1_007844 COc1cc(Cl)c(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M13 compound treatment 969690.0 419000.0 0.6 959801.0 354000.0 0.49 0.7701 0.9956 2073688 Maybridge1_007845 Nc1nc(ncc1C#N)c2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M14 compound treatment 908370.0 357000.0 0.51 929666.0 324000.0 0.45 0.6787 0.9983 2073689 Maybridge1_007846 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2ccc(OC(F)(F)F)cc2Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M15 compound treatment 938731.0 388000.0 0.55 929756.0 324000.0 0.45 0.7093 0.9951 2073690 Maybridge1_007847 Cc1cc(/C=N/NC(=O)N)c(C)n1c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M16 compound treatment 902563.0 352000.0 0.5 900797.0 295000.0 0.41 0.6444 0.9953 1353764 Maybridge1_007848 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M17 compound treatment 898665.0 348000.0 0.49 919354.0 313000.0 0.44 0.6588 0.9981 2073691 Maybridge1_007849 FC(F)(F)Oc1ccc(NC(=O)OC(Cc2ccccc2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M18 compound treatment 889445.0 339000.0 0.48 947017.0 341000.0 0.48 0.6768 1.0 2073692 Maybridge1_007850 COc1ccc2cc(ccc2c1)c3ccn[nH]3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M19 compound treatment 960603.0 410000.0 0.58 968095.0 362000.0 0.51 0.7691 0.9975 2073693 Maybridge1_007851 NS(=O)(=O)c1ccc(F)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M20 compound treatment 924266.0 373000.0 0.53 976980.0 371000.0 0.52 0.7413 0.9999 2073694 Maybridge1_007852 O=C/1/C(=C/c2ccco2)/COC\C1=C/c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M21 compound treatment 945848.0 395000.0 0.56 936266.0 330000.0 0.46 0.7229 0.9952 2073695 Maybridge1_007853 CN(C)c1cc(cnc1C(=S)C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M22 compound treatment 896238.0 345000.0 0.49 945608.0 340000.0 0.47 0.6822 0.9998 1004095 Maybridge1_007854 O=C(N1CCOCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M23 mock treatment 930499.0 380000.0 0.54 952679.0 347000.0 0.48 0.7236 0.9985 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 M24 mock treatment 697520.0 147000.0 0.21 600358.0 -5600.0 -0.01 0.1419 0.6801 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N01 compound treatment 824311.0 273000.0 0.39 845784.0 240000.0 0.33 0.5114 0.9972 2073696 Maybridge1_007855 FC(F)(F)c1ccc(NC2OC(=O)c3ccccc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N02 compound treatment 829537.0 279000.0 0.4 891044.0 285000.0 0.4 0.5613 1.0 2073697 Maybridge1_007856 CC(=O)c1ccc(o1)c2ccccc2OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N03 compound treatment 894486.0 344000.0 0.49 934454.0 328000.0 0.46 0.6694 0.9995 2073698 Maybridge1_007857 COC(=O)c1sc(c(c1/N=C/N)c2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N04 compound treatment 902065.0 351000.0 0.5 943639.0 338000.0 0.47 0.6861 0.9996 2073699 Maybridge1_007858 CCOC(=O)N/N=C/1\C(=O)Nc2ccc(F)cc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N05 compound treatment 852640.0 302000.0 0.43 992800.0 387000.0 0.54 0.6849 0.9936 2073700 Maybridge1_007859 Fc1cc(F)cc(COc2cc(Cl)cc(Cl)c2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N06 compound treatment 875079.0 324000.0 0.46 921857.0 316000.0 0.44 0.6375 0.9997 2073701 Maybridge1_007860 CC/C(=N\OC(=O)Nc1cc(Cl)cc(Cl)c1)/c2ccc(cc2)c3ccccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N07 compound treatment 906419.0 356000.0 0.51 955082.0 349000.0 0.49 0.7018 0.9998 2073702 Maybridge1_007861 CC(C)c1ccc(C)c2c(/C=N\NC(=S)N)cc(C)c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N08 compound treatment 907082.0 356000.0 0.51 937375.0 331000.0 0.46 0.685 0.999 1490455 Maybridge1_007862 Fc1ccccc1c2ccc(cc2)C(=O)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N09 compound treatment 935077.0 384000.0 0.55 961253.0 355000.0 0.5 0.7367 0.9988 1320292 Maybridge1_007863 CCc1ccc(C)nc1NC(=O)c2snnc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N10 compound treatment 881583.0 331000.0 0.47 944784.0 339000.0 0.47 0.6667 1.0 2073703 Maybridge1_007864 COC(=O)c1cc(ccc1N2CCCC2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N11 compound treatment 917956.0 367000.0 0.52 974378.0 368000.0 0.51 0.7324 1.0 1079409 Maybridge1_007865 N#Cc1nc(c2ccccc2)c(nc1C#N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N12 compound treatment 899947.0 349000.0 0.5 940268.0 334000.0 0.47 0.6807 0.9995 1695330 Maybridge1_007866 COc1ccc(NC(=O)c2ccc(cc2)c3ccccc3F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N13 compound treatment 868304.0 317000.0 0.45 968260.0 362000.0 0.51 0.6765 0.9984 2073704 Maybridge1_007867 Clc1sc(cc1Br)S(=O)(=O)N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N14 compound treatment 842428.0 292000.0 0.41 926403.0 320000.0 0.45 0.6092 0.9993 2073705 Maybridge1_007868 Fc1ccc2SCC/C(=N\OC(=O)c3ccc(Cl)cc3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N15 compound treatment 969758.0 419000.0 0.6 976624.0 371000.0 0.52 0.7867 0.9975 1454399 Maybridge1_007869 COc1ccc(CNCc2cc(OC)c(OC)c(OC)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N16 compound treatment 909783.0 359000.0 0.51 926766.0 321000.0 0.45 0.6772 0.9979 2073706 Maybridge1_007870 Nc1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N17 compound treatment 874921.0 324000.0 0.46 981150.0 375000.0 0.52 0.6958 0.998 2073707 Maybridge1_007871 Fc1ccc(NN=C(C#N)C#N)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N18 compound treatment 876525.0 326000.0 0.46 927220.0 321000.0 0.45 0.6442 0.9999 2073708 Maybridge1_007872 Cc1ccc(cc1)c2csc(n2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N19 compound treatment 919818.0 369000.0 0.52 1015360.0 409000.0 0.57 0.7747 0.9991 2073709 Maybridge1_007873 COC(=O)c1cccn1c2ccccc2C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N20 compound treatment 879720.0 329000.0 0.47 973728.0 368000.0 0.51 0.6933 0.9989 2073710 Maybridge1_007874 [O-][N+](=O)c1cc(ccc1Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N21 compound treatment 910014.0 359000.0 0.51 1021440.0 415000.0 0.58 0.7708 0.998 1566906 Maybridge1_007875 O=C(CC1(CC2CC3CC(C2)C1)C3)Nc4nccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N22 compound treatment 902419.0 352000.0 0.5 975854.0 370000.0 0.52 0.7182 0.9999 1567147 Maybridge1_007876 OC1(CCOCC1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N23 mock treatment 894196.0 343000.0 0.49 986361.0 380000.0 0.53 0.7203 0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 N24 mock treatment 660188.0 109000.0 0.16 722294.0 116000.0 0.16 0.2246 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O01 compound treatment 833455.0 283000.0 0.4 813820.0 208000.0 0.29 0.4891 0.9872 2073711 Maybridge1_007877 Cc1nn(C)c(O)c1N=Nc2ccc(cc2)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O02 compound treatment 840557.0 290000.0 0.41 854549.0 249000.0 0.35 0.5364 0.9963 2073712 Maybridge1_007878 Cc1nn(c(O)c1N=Nc2ccc(cc2)C(C)(C)C)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O03 compound treatment 879320.0 328000.0 0.47 867946.0 262000.0 0.37 0.5886 0.9926 2073713 Maybridge1_007879 COC(=O)c1sc(c(c1N)c2ccccc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O04 compound treatment 875270.0 324000.0 0.46 887457.0 281000.0 0.39 0.6038 0.9968 2073714 Maybridge1_007880 FC(F)(F)c1ccc(NC(=O)Nc2ccccc2)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O05 compound treatment 900820.0 350000.0 0.5 887025.0 281000.0 0.39 0.629 0.993 1138575 Maybridge1_007881 N#Cc1c(nsc1c2ccccc2)N3CCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O06 compound treatment 888683.0 338000.0 0.48 878616.0 273000.0 0.38 0.6085 0.9933 2073715 Maybridge1_007882 CCOC(=O)c1c(C)nn(c1C)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O07 compound treatment 917180.0 366000.0 0.52 924213.0 318000.0 0.44 0.6822 0.9968 2073716 Maybridge1_007883 N/C(=N\O)/c1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O08 compound treatment 884313.0 333000.0 0.47 893741.0 288000.0 0.4 0.6191 0.9966 2073717 Maybridge1_007884 Cc1nn(c(C)c1C(=O)NNC(=O)c2ccc(Cl)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O09 compound treatment 942838.0 392000.0 0.56 927106.0 321000.0 0.45 0.7108 0.9941 2073718 Maybridge1_007885 Brc1ccc(cc1)c2csc(Nc3cccnc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O10 compound treatment 861065.0 310000.0 0.44 892205.0 286000.0 0.4 0.5942 0.9988 1705189 Maybridge1_007886 Cc1noc(C)c1C(=O)N2CCC(CC2)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O11 compound treatment 950289.0 399000.0 0.57 890173.0 284000.0 0.4 0.6819 0.9845 2073719 Maybridge1_007887 CC(=O)c1csc(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O12 compound treatment 899075.0 348000.0 0.5 878215.0 272000.0 0.38 0.6186 0.9914 2073720 Maybridge1_007888 COc1cc(Cl)c(NS(=O)(=O)c2cc(Br)c(Br)s2)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O13 compound treatment 949999.0 399000.0 0.57 905203.0 299000.0 0.42 0.6964 0.9886 2073721 Maybridge1_007889 FC(F)(F)c1ccc(C=C(C#N)C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O14 compound treatment 899712.0 349000.0 0.5 926642.0 321000.0 0.45 0.667 0.9987 1241193 Maybridge1_007890 Cc1cc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O15 compound treatment 961849.0 411000.0 0.58 936284.0 330000.0 0.46 0.739 0.9931 2073722 Maybridge1_007891 FC(F)(F)c1ccc(CNS(=O)(=O)c2cc(Br)c(Br)s2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O16 compound treatment 869587.0 319000.0 0.45 907559.0 302000.0 0.42 0.6179 0.9993 1559301 Maybridge1_007892 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(CC2)C(=O)NS(=O)(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O17 compound treatment 930078.0 379000.0 0.54 937983.0 332000.0 0.46 0.7087 0.9971 2073723 Maybridge1_007893 O=C(CC(C(=O)c1cccs1)c2ccsc2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O18 compound treatment 870599.0 320000.0 0.45 919162.0 313000.0 0.44 0.6303 0.9998 2073724 Maybridge1_007894 NC(=S)c1c(Cl)cc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O19 compound treatment 932720.0 382000.0 0.54 958695.0 353000.0 0.49 0.7318 0.9988 2073725 Maybridge1_007895 NC(=O)c1sccc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O20 compound treatment 903551.0 353000.0 0.5 901132.0 295000.0 0.41 0.6457 0.9952 2073726 Maybridge1_007896 CCCCNC(=O)O/N=C(\C)/c1ccc2cc(OC)ccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O21 compound treatment 916824.0 366000.0 0.52 939316.0 333000.0 0.46 0.6967 0.9984 2073727 Maybridge1_007897 COC(=O)c1ccc(/C=C/c2cccc(Cl)c2)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O22 compound treatment 861579.0 311000.0 0.44 904270.0 298000.0 0.42 0.6066 0.9996 2073728 Maybridge1_007898 Clc1ccc(cc1)C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O23 mock treatment 915007.0 364000.0 0.52 916492.0 311000.0 0.43 0.6724 0.9961 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 O24 mock treatment 504645.0 -46300.0 -0.07 547836.0 -58100.0 -0.08 -0.1039 -0.9946 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P01 compound treatment 807857.0 257000.0 0.37 816518.0 211000.0 0.29 0.466 0.9941 2073729 Maybridge1_007899 Cc1onc(c1/C=C\2/C(=O)Nc3ccccc23)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P02 compound treatment 2320594.0 1770000.0 2.52 2245208.0 1640000.0 2.29 3.3962 0.9989 2073730 Maybridge1_007900 Fc1ccc2NC(=O)/C(=N\Nc3ccccc3)/c2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P03 compound treatment 848058.0 297000.0 0.42 852513.0 247000.0 0.34 0.5419 0.9948 2073731 Maybridge1_007901 Fc1ccc(cc1)n2cccc2C(=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P04 compound treatment 838470.0 288000.0 0.41 842375.0 236000.0 0.33 0.5223 0.9943 2073732 Maybridge1_007902 NC(=O)c1ccc(cc1)c2ccccc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P05 compound treatment 856072.0 305000.0 0.43 850485.0 245000.0 0.34 0.548 0.9929 2073733 Maybridge1_007903 Cc1cc(OCc2cc(F)cc(F)c2)ccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P06 compound treatment 1033255.0 482000.0 0.69 1061751.0 456000.0 0.64 0.9345 0.9993 2073734 Maybridge1_007904 [O-][N+](=O)c1ccc(N/N=C/c2ccc(o2)c3cc(ccc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P07 compound treatment 873575.0 323000.0 0.46 864387.0 258000.0 0.36 0.5793 0.9929 2073735 Maybridge1_007905 FC(F)(F)c1cccc(c1)c2ccnc3c(C#N)cnn23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P08 compound treatment 850994.0 300000.0 0.43 857038.0 251000.0 0.35 0.5494 0.9952 2073736 Maybridge1_007906 NC(=S)Nc1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P09 compound treatment 873828.0 323000.0 0.46 867766.0 262000.0 0.37 0.5829 0.9936 1682759 Maybridge1_007907 CCOC(=O)N1CCN(CN2CCCCC2=O)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P10 compound treatment 862866.0 312000.0 0.44 857875.0 252000.0 0.35 0.5621 0.9933 2073737 Maybridge1_007908 Cc1sc(Nc2cc(Cl)cc(Cl)c2)nc1c3ccc(cc3)c4ccccc4F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P11 compound treatment 833756.0 283000.0 0.4 851009.0 245000.0 0.34 0.5261 0.9967 1033603 Maybridge1_007909 CCOC(=O)Nc1ccc(F)cc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P12 compound treatment 864054.0 313000.0 0.45 865627.0 260000.0 0.36 0.571 0.9947 2073738 Maybridge1_007910 Fc1ccccc1c2ccc(cc2)C(=O)Nc3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P13 compound treatment 858074.0 307000.0 0.44 877242.0 271000.0 0.38 0.5764 0.9974 2073739 Maybridge1_007911 Clc1sc(cc1Br)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P14 compound treatment 883058.0 332000.0 0.47 875485.0 270000.0 0.38 0.5998 0.9936 2073740 Maybridge1_007912 Fc1ccc2SCc3cn(nc3-c2c1)C(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P15 compound treatment 844445.0 294000.0 0.42 860006.0 254000.0 0.35 0.5457 0.9967 2073741 Maybridge1_007913 FC(F)(F)c1cc(NN=C(C#N)C#N)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P16 compound treatment 892923.0 342000.0 0.49 897446.0 291000.0 0.41 0.6314 0.996 2073742 Maybridge1_007914 N/C(=N\O)/COc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P17 compound treatment 899536.0 349000.0 0.5 903179.0 297000.0 0.41 0.6437 0.996 2073743 Maybridge1_007915 COC(=O)CCCCCCCC(=O)Nc1ccc(OC)c(OC)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P18 compound treatment 872321.0 321000.0 0.46 867399.0 261000.0 0.36 0.581 0.9937 1632182 Maybridge1_007916 Cc1ccc(cc1)c2csc(n2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P19 compound treatment 880554.0 330000.0 0.47 900165.0 294000.0 0.41 0.6216 0.9978 2073744 Maybridge1_007917 FC(F)(F)c1ccnc(c1)N2CCN(CC2)C(=O)Nc3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P20 compound treatment 860658.0 310000.0 0.44 895382.0 289000.0 0.4 0.5969 0.9991 2073745 Maybridge1_007918 COc1cc(cc(c1C(=O)O)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P21 compound treatment 845969.0 295000.0 0.42 906503.0 301000.0 0.42 0.5931 1.0 1012024 Maybridge1_007919 N#CC(C(C#N)c1ccccc1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P22 compound treatment 850919.0 300000.0 0.43 885813.0 280000.0 0.39 0.5777 0.999 2073746 Maybridge1_007920 COc1cc(cc(c1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P23 mock treatment 822219.0 271000.0 0.39 855223.0 249000.0 0.35 0.5186 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.563 P24 mock treatment 235920.0 -315000.0 -0.45 254297.0 -352000.0 -0.49 -0.6636 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A01 compound treatment 734748.0 212000.0 0.3 773561.0 225000.0 0.31 0.4349 0.9998 2073747 Maybridge1_007921 FC(F)(F)c1cc(Oc2ccc(C#N)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A02 compound treatment 744629.0 222000.0 0.32 794522.0 246000.0 0.34 0.4655 0.9991 1556858 Maybridge1_007922 Cc1noc(C)c1C(=O)NCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A03 compound treatment 774486.0 252000.0 0.36 828640.0 280000.0 0.39 0.5291 0.9991 2073748 Maybridge1_007923 O=S(=O)(/C(=C/c1ccc(Oc2ccccc2)nc1)/C#N)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A04 compound treatment 768354.0 246000.0 0.35 812034.0 263000.0 0.37 0.5066 0.9997 1662020 Maybridge1_007924 CC(C)(C)c1ccc(s1)C(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A05 compound treatment 790534.0 268000.0 0.38 839753.0 291000.0 0.41 0.5562 0.9995 2073749 Maybridge1_007925 CSc1ccc([N+](=O)[O-])c(SC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A06 compound treatment 795930.0 273000.0 0.39 844904.0 296000.0 0.41 0.5667 0.9995 2073750 Maybridge1_007926 COc1cc(NC(=S)Nc2ccc(Cl)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A07 compound treatment 767054.0 244000.0 0.35 804490.0 256000.0 0.36 0.4979 0.9999 2073751 Maybridge1_007927 Nc1ccccc1Sc2nc(ccc2[N+](=O)[O-])c3ccccc3N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A08 compound treatment 824938.0 302000.0 0.43 851753.0 303000.0 0.42 0.6027 1.0 2073752 Maybridge1_007928 COc1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A09 compound treatment 799859.0 277000.0 0.39 861703.0 313000.0 0.44 0.5873 0.9987 2073753 Maybridge1_007929 Cc1ccc(cc1)C2CC=CCC2[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A10 compound treatment 791376.0 269000.0 0.38 882493.0 334000.0 0.47 0.5992 0.9952 2073754 Maybridge1_007930 CC(C)(C)C(=O)N1CCN(CC1)c2ncccc2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A11 compound treatment 797494.0 275000.0 0.39 855223.0 307000.0 0.43 0.5785 0.999 2073755 Maybridge1_007931 FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc[nH]2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A12 compound treatment 827887.0 305000.0 0.43 879121.0 330000.0 0.46 0.6326 0.9995 2073756 Maybridge1_007932 Cc1noc(C)c1C(=O)O/N=C(\N)/c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A13 compound treatment 927024.0 404000.0 0.57 1085223.0 537000.0 0.75 0.9356 0.9915 2073757 Maybridge1_007933 COC(=O)c1cccn1S(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A14 compound treatment 850410.0 328000.0 0.47 886634.0 338000.0 0.47 0.6627 1.0 2073758 Maybridge1_007934 Cc1noc(C)c1c2nc(no2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A15 compound treatment 830222.0 307000.0 0.44 880731.0 332000.0 0.46 0.6366 0.9996 1027194 Maybridge1_007935 COc1ccc(Oc2ccc(cc2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A16 compound treatment 819944.0 297000.0 0.42 883414.0 335000.0 0.47 0.6289 0.9988 2073759 Maybridge1_007936 Cc1onc(c1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A17 compound treatment 827837.0 305000.0 0.43 851189.0 303000.0 0.42 0.605 0.9999 2073760 Maybridge1_007937 CN1CCN(CC1)c2ccccc2/C=N\NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A18 compound treatment 830615.0 308000.0 0.44 858187.0 310000.0 0.43 0.6147 1.0 2073761 Maybridge1_007938 FC(F)(F)c1cnc(N2CCN(CC2)S(=O)(=O)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A19 compound treatment 825855.0 303000.0 0.43 864016.0 315000.0 0.44 0.6157 0.9999 2073762 Maybridge1_007939 FC(F)(F)c1cc(NC(=O)NC(=O)c2cc(Br)cc(Br)c2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A20 compound treatment 839774.0 317000.0 0.45 859187.0 311000.0 0.43 0.6249 0.9998 2073763 Maybridge1_007940 Cc1ccc(C)n1c2ccc(cc2)n3nc(cc3C(C)(C)C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A21 compound treatment 811680.0 289000.0 0.41 801958.0 253000.0 0.35 0.5402 0.9972 1304594 Maybridge1_007941 Cc1noc(C)c1C(=O)Nc2ccccc2Oc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A22 compound treatment 780521.0 258000.0 0.37 794129.0 245000.0 0.34 0.5012 0.9994 1380697 Maybridge1_007942 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A23 mock treatment 768403.0 246000.0 0.35 767475.0 219000.0 0.31 0.4627 0.9977 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 A24 mock treatment 137841.0 -385000.0 -0.55 133314.0 -415000.0 -0.58 -0.7968 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B01 compound treatment 747142.0 224000.0 0.32 783778.0 235000.0 0.33 0.4574 0.9999 2073764 Maybridge1_007943 Cc1cc(C)cc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B02 compound treatment 722196.0 199000.0 0.28 814452.0 266000.0 0.37 0.4626 0.9912 1172726 Maybridge1_007944 Cc1ccc(cc1)C(=O)Oc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B03 compound treatment 768862.0 246000.0 0.35 906028.0 357000.0 0.5 0.5998 0.985 2073765 Maybridge1_007945 Cc1cccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B04 compound treatment 783504.0 261000.0 0.37 880048.0 331000.0 0.46 0.5889 0.994 1119199 Maybridge1_007946 COC(=O)c1cc(OC)ccc1Oc2cccc(OC)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B05 compound treatment 788314.0 265000.0 0.38 923778.0 375000.0 0.52 0.6369 0.9872 1683143 Maybridge1_007947 COc1ccccc1N2CCN(CC2)C(=O)c3c(C)onc3c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B06 compound treatment 785524.0 263000.0 0.37 880532.0 332000.0 0.46 0.5914 0.9944 2073766 Maybridge1_007948 OC(=O)C1CN(C(=O)C1)c2cccc(c2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B07 compound treatment 818859.0 296000.0 0.42 924663.0 376000.0 0.52 0.6685 0.9941 1509551 Maybridge1_007949 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B08 compound treatment 767395.0 245000.0 0.35 855518.0 307000.0 0.43 0.5485 0.9947 2073767 Maybridge1_007950 COc1ccc(cc1)c2n[nH]cc2/C=N/Nc3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B09 compound treatment 828256.0 305000.0 0.43 931325.0 383000.0 0.53 0.6845 0.9948 2073768 Maybridge1_007951 CCc1cc2c(cc1c3csc(n3)c4ccccc4)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B10 compound treatment 809590.0 287000.0 0.41 932062.0 383000.0 0.53 0.6664 0.9911 2073769 Maybridge1_007952 COc1ccc(cc1)c2n[nH]cc2/C=N/NC(=S)NC3CC4CCC3C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B11 compound treatment 828797.0 306000.0 0.44 951113.0 402000.0 0.56 0.7045 0.9921 1410819 Maybridge1_007953 COc1ccccc1N2CCN(CC2)C(=O)Nc3cccc(Cl)c3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B12 compound treatment 816228.0 293000.0 0.42 912491.0 364000.0 0.51 0.6538 0.9953 2073770 Maybridge1_007954 COc1ccc(cc1)C2N(CCc3sccc23)C(=S)Nc4ccc(OC(F)(F)F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B13 compound treatment 859379.0 337000.0 0.48 954895.0 406000.0 0.57 0.739 0.9965 1504486 Maybridge1_007955 COc1ccccc1N2CCN(CC2)C(=S)Nc3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B14 compound treatment 856125.0 333000.0 0.47 937373.0 389000.0 0.54 0.7185 0.9978 2073771 Maybridge1_007956 CC(C)(C)c1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B15 compound treatment 900308.0 377000.0 0.54 945173.0 396000.0 0.55 0.7706 0.9999 2073772 Maybridge1_007957 CCC(C)CNC(=S)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B16 compound treatment 864890.0 342000.0 0.49 892725.0 344000.0 0.48 0.6833 1.0 2073773 Maybridge1_007958 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCSCc2c(C)cc(C)cc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B17 compound treatment 911388.0 389000.0 0.55 927969.0 379000.0 0.53 0.7648 0.9998 2073774 Maybridge1_007959 COC(=O)/C(=C/c1cccn1c2ccc(cc2)C(F)(F)F)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B18 compound treatment 818700.0 296000.0 0.42 859019.0 310000.0 0.43 0.6036 0.9999 1652319 Maybridge1_007960 COc1ccccc1N2CCN(CC(=S)N)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B19 compound treatment 909209.0 386000.0 0.55 910460.0 362000.0 0.5 0.7453 0.9991 2073775 Maybridge1_007961 OC(=O)COCC(=O)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B20 compound treatment 849902.0 327000.0 0.47 831251.0 283000.0 0.39 0.6076 0.9966 2073776 Maybridge1_007962 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)CCSc3cccs3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B21 compound treatment 845999.0 323000.0 0.46 830960.0 282000.0 0.39 0.6033 0.997 2073777 Maybridge1_007963 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)Nc4cc(Cl)cc(Cl)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B22 compound treatment 835727.0 313000.0 0.44 829544.0 281000.0 0.39 0.5916 0.998 2073778 Maybridge1_007964 COc1cc(Br)cc(/C=N/CCSCc2ccccc2Cl)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B23 mock treatment 770776.0 248000.0 0.35 799184.0 250000.0 0.35 0.4964 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 B24 mock treatment 118258.0 -405000.0 -0.58 131428.0 -417000.0 -0.58 -0.8183 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C01 compound treatment 750031.0 227000.0 0.32 794691.0 246000.0 0.34 0.4711 0.9995 1385577 Maybridge1_007965 COC(=O)c1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)ccc1N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C02 compound treatment 775064.0 252000.0 0.36 853356.0 305000.0 0.42 0.5541 0.9964 2073779 Maybridge1_007966 Cc1nnsc1C(=O)Nc2cccc(N)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C03 compound treatment 820452.0 298000.0 0.42 923550.0 375000.0 0.52 0.669 0.9945 2073780 Maybridge1_007967 CC1(C)OC(=O)C(=Cc2ccc(Oc3ccccc3)nc2)C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C04 compound treatment 819060.0 296000.0 0.42 914747.0 366000.0 0.51 0.6589 0.9954 2073781 Maybridge1_007968 CC(C)(C)c1ccc(s1)C(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C05 compound treatment 846728.0 324000.0 0.46 933423.0 385000.0 0.54 0.7051 0.9971 2073782 Maybridge1_007969 [O-][N+](=O)c1ccc(nc1N2CCCCC2)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C06 compound treatment 789933.0 267000.0 0.38 899117.0 350000.0 0.49 0.6142 0.9922 2073783 Maybridge1_007970 COc1cccc(NC(=O)Nc2cc(OC)cc(c2)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C07 compound treatment 780678.0 258000.0 0.37 891498.0 343000.0 0.48 0.5974 0.9914 2073784 Maybridge1_007971 Cn1c(Sc2ccc([N+](=O)[O-])c(Sc3nnc(n3C)C(F)(F)F)n2)nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C08 compound treatment 864349.0 342000.0 0.49 941524.0 393000.0 0.55 0.7308 0.9982 2073785 Maybridge1_007972 COC(=O)c1ccc(CSc2ccccn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C09 compound treatment 859227.0 336000.0 0.48 957355.0 409000.0 0.57 0.7413 0.9962 1501900 Maybridge1_007973 Clc1ccc2nc(sc2c1)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C10 compound treatment 864016.0 341000.0 0.49 928120.0 379000.0 0.53 0.7173 0.9991 2073786 Maybridge1_007974 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C11 compound treatment 896213.0 373000.0 0.53 968280.0 420000.0 0.59 0.7893 0.9988 2073787 Maybridge1_007975 Cc1ccc(NC(=S)NNC(=O)c2ccc[nH]2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C12 compound treatment 883624.0 361000.0 0.51 967728.0 419000.0 0.58 0.7761 0.9979 2073788 Maybridge1_007976 Cc1noc(C)c1C(=O)O/N=C(\N)/c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C13 compound treatment 912318.0 389000.0 0.55 946989.0 398000.0 0.56 0.7845 1.0 2073789 Maybridge1_007977 CN(C)c1ccc(/C=N/Nc2cnc3ccccc3n2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C14 compound treatment 862672.0 340000.0 0.48 916014.0 367000.0 0.51 0.704 0.9996 2073790 Maybridge1_007978 Cc1ccc(cc1)C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C15 compound treatment 905262.0 382000.0 0.54 999025.0 450000.0 0.63 0.8287 0.9974 2073791 Maybridge1_007979 CCOC(=O)c1ccc(cc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C16 compound treatment 904634.0 382000.0 0.54 942111.0 393000.0 0.55 0.7719 1.0 2073792 Maybridge1_007980 Cc1onc(c1C(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C17 compound treatment 896854.0 374000.0 0.53 962009.0 413000.0 0.58 0.7837 0.9992 1672229 Maybridge1_007981 COc1cccc(c1)c2nc(C#N)c(N)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C18 compound treatment 846132.0 323000.0 0.46 955545.0 407000.0 0.57 0.7263 0.9945 2073793 Maybridge1_007982 FC(F)(F)c1cnc(N2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C19 compound treatment 878576.0 356000.0 0.51 925498.0 377000.0 0.53 0.7293 0.9998 1127055 Maybridge1_007983 CN(Cc1ccccc1)S(=O)(=O)c2c(C)noc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C20 compound treatment 846518.0 324000.0 0.46 898724.0 350000.0 0.49 0.6707 0.9996 2073794 Maybridge1_007984 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)NCc3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C21 compound treatment 859394.0 337000.0 0.48 897313.0 349000.0 0.49 0.6823 1.0 1397120 Maybridge1_007985 Cc1noc(C)c1S(=O)(=O)Nc2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C22 compound treatment 815725.0 293000.0 0.42 841767.0 293000.0 0.41 0.5836 1.0 1706710 Maybridge1_007986 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(s3)c4cnoc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C23 mock treatment 822541.0 300000.0 0.43 831022.0 282000.0 0.39 0.5798 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 C24 mock treatment 118531.0 -404000.0 -0.57 156868.0 -392000.0 -0.55 -0.793 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D01 compound treatment 782298.0 259000.0 0.37 807052.0 258000.0 0.36 0.5157 0.9999 2073795 Maybridge1_007987 COc1ccc(OC)c(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D02 compound treatment 771719.0 249000.0 0.35 812828.0 264000.0 0.37 0.5108 0.9998 2073796 Maybridge1_007988 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)CSc3ccccn3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D03 compound treatment 826321.0 303000.0 0.43 928683.0 380000.0 0.53 0.6799 0.9948 2073797 Maybridge1_007989 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)Nc3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D04 compound treatment 822527.0 300000.0 0.43 905696.0 357000.0 0.5 0.6534 0.997 2073798 Maybridge1_007990 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D05 compound treatment 807741.0 285000.0 0.41 905559.0 357000.0 0.5 0.6384 0.9948 1535919 Maybridge1_007991 CCN(CC)c1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)c(n1)N(CC)CC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D06 compound treatment 843641.0 321000.0 0.46 860527.0 312000.0 0.43 0.6301 0.9997 2073799 Maybridge1_007992 COc1ccc(/N=C/c2ccc(N(C)C)c(C#N)c2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D07 compound treatment 844815.0 322000.0 0.46 952709.0 404000.0 0.56 0.7222 0.9947 2073800 Maybridge1_007993 Cc1noc(C)c1c2nc(no2)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D08 compound treatment 873568.0 351000.0 0.5 943298.0 395000.0 0.55 0.7419 0.9988 2073801 Maybridge1_007994 COc1ccc(cc1)C(=O)NCCSCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D09 compound treatment 854390.0 332000.0 0.47 963853.0 415000.0 0.58 0.7428 0.9948 1578068 Maybridge1_007995 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D10 compound treatment 874692.0 352000.0 0.5 928593.0 380000.0 0.53 0.7285 0.9996 2073802 Maybridge1_007996 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2SCc3noc(n3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D11 compound treatment 916476.0 394000.0 0.56 924778.0 376000.0 0.52 0.7667 0.9995 1434748 Maybridge1_007997 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D12 compound treatment 853801.0 331000.0 0.47 924663.0 376000.0 0.52 0.7036 0.9985 2073803 Maybridge1_007998 Cc1ccc(c(NC(=O)c2cccc(c2)C(F)(F)F)c1)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D13 compound treatment 938111.0 415000.0 0.59 954327.0 406000.0 0.57 0.8176 0.9998 1219861 Maybridge1_007999 COc1ccccc1N2CCN(CC2)C(=S)Nc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D14 compound treatment 810903.0 288000.0 0.41 958524.0 410000.0 0.57 0.6939 0.9867 2073804 Maybridge1_008000 Fc1cccc(Cl)c1C(=O)Nc2ccc(Oc3cc(cc(c3)C(F)(F)F)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D15 compound treatment 930598.0 408000.0 0.58 963526.0 415000.0 0.58 0.8192 1.0 2073805 Maybridge1_008001 CN(C)c1ccc(/C=N/NC(=S)N)cc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D16 compound treatment 923725.0 401000.0 0.57 954714.0 406000.0 0.57 0.8036 1.0 2073806 Maybridge1_008002 Cc1cc(C)c(CSCCNC(=O)Nc2ccc(F)cc2F)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D17 compound treatment 942718.0 420000.0 0.6 945108.0 396000.0 0.55 0.8132 0.9993 2073807 Maybridge1_008003 NC(=S)N/N=C/c1cccn1c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D18 compound treatment 914461.0 392000.0 0.56 903204.0 355000.0 0.49 0.7434 0.9982 2073808 Maybridge1_008004 Cc1onc(c1C(=O)Nc2ccccc2SCc3noc(n3)c4cccs4)c5c(Cl)cccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D19 compound treatment 928871.0 406000.0 0.58 930841.0 382000.0 0.53 0.7852 0.9992 2073809 Maybridge1_008005 FC(F)(F)C1N(CCc2c1[nH]c3ccccc23)C(=O)NC(=O)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D20 compound treatment 901148.0 378000.0 0.54 911603.0 363000.0 0.51 0.7383 0.9995 2073810 Maybridge1_008006 FC(F)(F)c1ccc(NC(=O)NCCSCc2ccccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D21 compound treatment 912698.0 390000.0 0.55 919827.0 371000.0 0.52 0.7581 0.9994 2073811 Maybridge1_008007 [O-][N+](=O)c1cccc(OCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D22 compound treatment 858524.0 336000.0 0.48 869353.0 321000.0 0.45 0.6538 0.9995 1142424 Maybridge1_008008 CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CCC(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D23 mock treatment 878144.0 355000.0 0.51 867454.0 319000.0 0.44 0.6717 0.998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 D24 mock treatment 89005.0 -434000.0 -0.62 142231.0 -406000.0 -0.57 -0.8371 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E01 compound treatment 755613.0 233000.0 0.33 792923.0 244000.0 0.34 0.4749 0.9999 1709671 Maybridge1_008009 COC(=O)c1cc(ccc1N2CCOCC2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E02 compound treatment 780168.0 257000.0 0.37 856976.0 308000.0 0.43 0.5628 0.9968 1559282 Maybridge1_008010 Cc1noc(C)c1C(=O)Oc2ccc(F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E03 compound treatment 838382.0 316000.0 0.45 900904.0 352000.0 0.49 0.6647 0.999 2073812 Maybridge1_008011 CCOC(=O)N/N=C(\C)/C(=N/NC(=O)OCC)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E04 compound treatment 845325.0 322000.0 0.46 878423.0 330000.0 0.46 0.6495 1.0 2073813 Maybridge1_008012 CC(C)(C)c1ccc(s1)C(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E05 compound treatment 853499.0 331000.0 0.47 946666.0 398000.0 0.56 0.725 0.9966 2073814 Maybridge1_008013 [O-][N+](=O)c1ccc(Sc2ccc(Cl)cc2)nc1Sc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E06 compound treatment 845547.0 323000.0 0.46 916483.0 368000.0 0.51 0.6872 0.9985 2073815 Maybridge1_008014 [O-][N+](=O)c1ccc(nc1)N2CCC(CC2)C(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E07 compound treatment 872124.0 349000.0 0.5 971084.0 422000.0 0.59 0.7678 0.9964 2073816 Maybridge1_008015 N#Cc1ccc(nc1)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E08 compound treatment 869297.0 346000.0 0.49 932278.0 384000.0 0.54 0.7267 0.9992 2073817 Maybridge1_008016 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E09 compound treatment 940845.0 418000.0 0.59 1021602.0 473000.0 0.66 0.8867 0.9987 2073818 Maybridge1_008017 COc1ccc(N)c(OC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E10 compound treatment 849669.0 327000.0 0.46 893162.0 344000.0 0.48 0.6684 0.9999 2073819 Maybridge1_008018 CC(C)(C)c1ccc(cc1)C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E11 compound treatment 879929.0 357000.0 0.51 954745.0 406000.0 0.57 0.7595 0.9985 2073820 Maybridge1_008019 [O-][N+](=O)c1cc(C#N)ccc1N/N=C/c2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E12 compound treatment 910589.0 388000.0 0.55 900140.0 351000.0 0.49 0.7365 0.9983 2073821 Maybridge1_008020 Cc1onc(c1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c4c(F)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E13 compound treatment 900720.0 378000.0 0.54 933008.0 384000.0 0.54 0.759 1.0 2073822 Maybridge1_008021 COc1ccc(Oc2ccc([N+](=O)[O-])c(Oc3ccc(OC)cc3)n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E14 compound treatment 877768.0 355000.0 0.5 913614.0 365000.0 0.51 0.7168 1.0 2073823 Maybridge1_008022 [O-][N+](=O)c1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E15 compound treatment 888617.0 366000.0 0.52 964566.0 416000.0 0.58 0.778 0.9985 1168565 Maybridge1_008023 OC(=O)C(c1ccccc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E16 compound treatment 892683.0 370000.0 0.53 954355.0 406000.0 0.57 0.772 0.9993 1273402 Maybridge1_008024 CC(C)(C)c1cc(n(n1)c2ccc(N)cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E17 compound treatment 952933.0 430000.0 0.61 1020684.0 472000.0 0.66 0.898 0.9993 2073824 Maybridge1_008025 Clc1ccc(c2ccon2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E18 compound treatment 896887.0 374000.0 0.53 924318.0 376000.0 0.52 0.7466 1.0 2073825 Maybridge1_008026 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E19 compound treatment 890050.0 367000.0 0.52 914011.0 365000.0 0.51 0.7295 0.9999 1524187 Maybridge1_008027 COc1ccc(NS(=O)(=O)c2c(C)noc2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E20 compound treatment 906877.0 384000.0 0.55 916405.0 368000.0 0.51 0.7488 0.9995 2073826 Maybridge1_008028 CNC(=S)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E21 compound treatment 844674.0 322000.0 0.46 901291.0 353000.0 0.49 0.6714 0.9994 1344467 Maybridge1_008029 Cc1noc(C)c1S(=O)(=O)N2CCSCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E22 compound treatment 860865.0 338000.0 0.48 874145.0 325000.0 0.45 0.6609 0.9996 1617817 Maybridge1_008030 COc1ccccc1N2CCN(CC2)C(=O)c3c(F)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E23 mock treatment 878447.0 356000.0 0.51 853915.0 305000.0 0.43 0.6586 0.9963 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 E24 mock treatment 124450.0 -398000.0 -0.57 135043.0 -414000.0 -0.58 -0.8085 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F01 compound treatment 788122.0 265000.0 0.38 811625.0 263000.0 0.37 0.5261 0.9999 2073827 Maybridge1_008031 Fc1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F02 compound treatment 809970.0 287000.0 0.41 886122.0 337000.0 0.47 0.6215 0.9975 1561192 Maybridge1_008032 Fc1cccc(F)c1C(=O)Oc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F03 compound treatment 826760.0 304000.0 0.43 934055.0 385000.0 0.54 0.6857 0.9942 2073828 Maybridge1_008033 FC(F)(F)Oc1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F04 compound treatment 849176.0 326000.0 0.46 929238.0 381000.0 0.53 0.7035 0.9978 2073829 Maybridge1_008034 FC(F)(F)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(C#N)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F05 compound treatment 851641.0 329000.0 0.47 929890.0 381000.0 0.53 0.7066 0.998 1402639 Maybridge1_008035 CCN(CC)c1ccc(NC(=O)c2c(F)cccc2F)c(n1)N(CC)CC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F06 compound treatment 863460.0 341000.0 0.48 932341.0 384000.0 0.54 0.7209 0.9988 2073830 Maybridge1_008036 CC(=O)CCC(=O)c1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F07 compound treatment 882558.0 360000.0 0.51 1003270.0 455000.0 0.63 0.81 0.9943 2073831 Maybridge1_008037 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)NC3CC4CC3C=C4)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F08 compound treatment 902242.0 379000.0 0.54 966342.0 418000.0 0.58 0.7934 0.9993 2073832 Maybridge1_008038 FC(F)(F)c1cccc(c1)C(=O)NCCSCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F09 compound treatment 876424.0 354000.0 0.5 1004732.0 456000.0 0.64 0.8053 0.9932 1560524 Maybridge1_008039 COc1ccccc1N2CCN(CC2)C(=O)Nc3cc(F)ccc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F10 compound treatment 921013.0 398000.0 0.57 967465.0 419000.0 0.58 0.8134 0.9999 2073833 Maybridge1_008040 Cc1ccc(cc1)C(=O)Nc2ccccc2SCc3noc(n3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F11 compound treatment 918333.0 395000.0 0.56 966826.0 418000.0 0.58 0.8101 0.9998 1517384 Maybridge1_008041 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F12 compound treatment 892131.0 369000.0 0.53 969096.0 420000.0 0.59 0.786 0.9985 2073834 Maybridge1_008042 COC(=O)c1cc(/C=N/NS(=O)(=O)c2ccc(C)cc2)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F13 compound treatment 910194.0 387000.0 0.55 983207.0 435000.0 0.61 0.818 0.9989 2073835 Maybridge1_008043 COc1ccccc1N2CCN(CC2)C(=S)Nc3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F14 compound treatment 879215.0 356000.0 0.51 940972.0 392000.0 0.55 0.7452 0.9993 2073836 Maybridge1_008044 FC(F)(F)c1cc(Oc2ccc(NC(=O)c3cccs3)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F15 compound treatment 945229.0 422000.0 0.6 972336.0 424000.0 0.59 0.8426 1.0 1441649 Maybridge1_008045 CCc1cc2c(cc1c3csc(N)n3)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F16 compound treatment 899385.0 377000.0 0.54 944979.0 396000.0 0.55 0.7695 0.9999 2073837 Maybridge1_008046 Cc1cc(C)c(CSCCNC(=O)Nc2ccc(OC(F)(F)F)cc2)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F17 compound treatment 950027.0 427000.0 0.61 987460.0 439000.0 0.61 0.8623 1.0 2073838 Maybridge1_008047 Cc1ccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F18 compound treatment 900425.0 378000.0 0.54 913293.0 365000.0 0.51 0.7393 0.9996 2073839 Maybridge1_008048 Cc1ccc(c(NC(=S)Nc2ccc(Br)cc2OC(F)(F)F)c1)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F19 compound treatment 925718.0 403000.0 0.57 985516.0 437000.0 0.61 0.8359 0.9995 2073840 Maybridge1_008049 COc1cccc(Cl)c1NC(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F20 compound treatment 924194.0 401000.0 0.57 943465.0 395000.0 0.55 0.7929 0.9998 2073841 Maybridge1_008050 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F21 compound treatment 939206.0 416000.0 0.59 955120.0 406000.0 0.57 0.8195 0.9998 2073842 Maybridge1_008051 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)COc3ccc4OCOc4c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F22 compound treatment 858859.0 336000.0 0.48 868406.0 320000.0 0.45 0.6532 0.9994 2073843 Maybridge1_008052 Clc1sc(Cl)c(c1Br)S(=O)(=O)NCCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F23 mock treatment 903272.0 380000.0 0.54 927487.0 379000.0 0.53 0.7561 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 F24 mock treatment 63618.0 -459000.0 -0.65 140512.0 -408000.0 -0.57 -0.8643 -0.9977 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G01 compound treatment 774144.0 251000.0 0.36 798028.0 249000.0 0.35 0.4986 0.9999 2073844 Maybridge1_008053 COc1ccc(cc1)C(=O)NNC(=O)c2c(OC)cc(cc2C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G02 compound treatment 778043.0 255000.0 0.36 860313.0 312000.0 0.43 0.564 0.996 2073845 Maybridge1_008054 Cc1noc(C)c1C(=O)Oc2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G03 compound treatment 823349.0 301000.0 0.43 903535.0 355000.0 0.49 0.6521 0.9973 2073846 Maybridge1_008055 CCOC(=O)N/N=C(\C)/c1ccccc1c2ccccc2\C(=N\NC(=O)OCC)\C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G04 compound treatment 834383.0 312000.0 0.44 883399.0 335000.0 0.47 0.6434 0.9997 2073847 Maybridge1_008056 COc1cc(NC(=S)NC(=O)c2ccccc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G05 compound treatment 881132.0 358000.0 0.51 990570.0 442000.0 0.62 0.7961 0.9955 2073848 Maybridge1_008057 Oc1ccc2ccccc2c1N=Nc3ccccc3OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G06 compound treatment 801047.0 278000.0 0.4 889232.0 341000.0 0.47 0.6156 0.9959 2073849 Maybridge1_008058 [O-][N+](=O)c1ccc(nc1)N2CCC(CC2)C(=O)c3ccc(F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G07 compound treatment 799819.0 277000.0 0.39 912465.0 364000.0 0.51 0.6373 0.9922 1329908 Maybridge1_008059 COc1ccc(NC(=O)C(C)c2ccc(CC(C)C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G08 compound treatment 864085.0 341000.0 0.49 930025.0 381000.0 0.53 0.7192 0.999 2073850 Maybridge1_008060 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G09 compound treatment 869211.0 346000.0 0.49 950326.0 402000.0 0.56 0.7444 0.9979 1164325 Maybridge1_008061 COC(=O)c1cccn1S(=O)(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G10 compound treatment 873172.0 350000.0 0.5 931783.0 383000.0 0.53 0.7301 0.9994 2073851 Maybridge1_008062 Oc1c(Br)cc(Br)cc1/C=N/c2ccc(Sc3ccccc3)nc2Sc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G11 compound treatment 892156.0 369000.0 0.53 925558.0 377000.0 0.53 0.7431 1.0 2073852 Maybridge1_008063 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G12 compound treatment 872794.0 350000.0 0.5 882485.0 334000.0 0.47 0.6811 0.9994 1457693 Maybridge1_008064 Cc1noc(C)c1C(=O)NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G13 compound treatment 893336.0 371000.0 0.53 930562.0 382000.0 0.53 0.7492 1.0 1044663 Maybridge1_008065 Nc1oc(nc1C#N)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G14 compound treatment 864991.0 342000.0 0.49 909825.0 361000.0 0.5 0.7002 0.9999 2073853 Maybridge1_008066 Cc1onc(c1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G15 compound treatment 937428.0 415000.0 0.59 962345.0 414000.0 0.58 0.8249 0.9999 1550324 Maybridge1_008067 OC(=O)c1ccc(cc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G16 compound treatment 844948.0 322000.0 0.46 908849.0 360000.0 0.5 0.6791 0.9989 2073854 Maybridge1_008068 FC(F)(F)c1ccc(nc1)N2CCN(CC2)c3ccc(NC(=O)c4ccc(Cl)cc4)cn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G17 compound treatment 932701.0 410000.0 0.58 976072.0 427000.0 0.6 0.8336 0.9999 2073855 Maybridge1_008069 CCOC(=O)c1cnn(c1C)c2ccc(N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G18 compound treatment 876199.0 353000.0 0.5 897813.0 349000.0 0.49 0.6996 0.9999 2073856 Maybridge1_008070 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G19 compound treatment 928085.0 405000.0 0.58 897981.0 349000.0 0.49 0.752 0.9965 1690043 Maybridge1_008071 Cc1noc(C)c1C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G20 compound treatment 901577.0 379000.0 0.54 897279.0 349000.0 0.49 0.7246 0.9987 2073857 Maybridge1_008072 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G21 compound treatment 833799.0 311000.0 0.44 849901.0 301000.0 0.42 0.6098 0.9997 2073858 Maybridge1_008073 CC(C)(C)c1cc(n(n1)c2ccc(cc2)[N+](=O)[O-])C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G22 compound treatment 823650.0 301000.0 0.43 850058.0 301000.0 0.42 0.5997 1.0 2073859 Maybridge1_008074 FC(F)(F)c1cnc(N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G23 mock treatment 879575.0 357000.0 0.51 863614.0 315000.0 0.44 0.6693 0.9974 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 G24 mock treatment 121632.0 -401000.0 -0.57 140879.0 -408000.0 -0.57 -0.8056 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H01 compound treatment 753437.0 231000.0 0.33 802639.0 254000.0 0.35 0.4823 0.9993 2073860 Maybridge1_008075 CCc1cc2c(cc1c3csc(n3)c4ccc(Cl)cc4)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H02 compound treatment 769572.0 247000.0 0.35 870874.0 322000.0 0.45 0.5659 0.9925 1965709 Maybridge1_008076 FC(F)(F)c1ccc(nc1)N2CCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H03 compound treatment 796199.0 273000.0 0.39 932234.0 384000.0 0.53 0.6531 0.9877 2073861 Maybridge1_008077 FC(F)(F)c1cccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H04 compound treatment 772746.0 250000.0 0.36 843672.0 295000.0 0.41 0.5422 0.9973 2073862 Maybridge1_008078 CC(C)Cc1ccc(cc1)C(C)c2nc(no2)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H05 compound treatment 841582.0 319000.0 0.45 934570.0 386000.0 0.54 0.7011 0.9964 2073863 Maybridge1_008079 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)NCC=C)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H06 compound treatment 831946.0 309000.0 0.44 875557.0 327000.0 0.46 0.6332 0.9998 2073864 Maybridge1_008080 CC(=O)CCC(=O)c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H07 compound treatment 862542.0 340000.0 0.48 942203.0 394000.0 0.55 0.7297 0.998 1387737 Maybridge1_008081 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(C)c(Cl)cc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H08 compound treatment 789333.0 266000.0 0.38 912258.0 364000.0 0.51 0.6265 0.9897 2073865 Maybridge1_008082 Fc1cccc(F)c1C(=O)NCCSCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H09 compound treatment 845873.0 323000.0 0.46 923744.0 375000.0 0.52 0.6947 0.9979 2073866 Maybridge1_008083 FC(F)(F)c1cnc(N2CCN(CC2)S(=O)(=O)c3ccc(C#N)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H10 compound treatment 864767.0 342000.0 0.49 905551.0 357000.0 0.5 0.6958 0.9999 2073867 Maybridge1_008084 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H11 compound treatment 871919.0 349000.0 0.5 941835.0 393000.0 0.55 0.7388 0.9988 2073868 Maybridge1_008085 Fc1ccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H12 compound treatment 869431.0 347000.0 0.49 915076.0 366000.0 0.51 0.7099 0.9998 2073869 Maybridge1_008086 [O-][N+](=O)c1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H13 compound treatment 910976.0 388000.0 0.55 937247.0 389000.0 0.54 0.7735 1.0 1347507 Maybridge1_008087 COc1ccccc1N2CCN(CC2)C(=S)Nc3c(C)cc(C)cc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H14 compound treatment 889247.0 366000.0 0.52 912931.0 364000.0 0.51 0.7277 0.9999 2073870 Maybridge1_008088 COC(=O)c1cc(/C=N/NC(=O)c2cccc(c2)[N+](=O)[O-])cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H15 compound treatment 897997.0 375000.0 0.53 939562.0 391000.0 0.55 0.7627 0.9999 2073871 Maybridge1_008089 CCc1cc2c(cc1c3csc(NC(=N)N)n3)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H16 compound treatment 871171.0 348000.0 0.5 903560.0 355000.0 0.49 0.7003 1.0 2073872 Maybridge1_008090 Cc1cc(C)c(CSCCNC(=O)Nc2cccc3ccccc23)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H17 compound treatment 915432.0 393000.0 0.56 963662.0 415000.0 0.58 0.804 0.9998 2073873 Maybridge1_008091 FC(F)(F)Oc1ccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H18 compound treatment 887441.0 365000.0 0.52 915919.0 367000.0 0.51 0.7288 1.0 1132312 Maybridge1_008092 Cc1ccc(c(NC(=S)NC(=O)c2ccccc2)c1)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H19 compound treatment 907303.0 384000.0 0.55 963593.0 415000.0 0.58 0.7958 0.9996 2073874 Maybridge1_008093 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)Nc3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H20 compound treatment 814851.0 292000.0 0.42 862056.0 313000.0 0.44 0.6027 0.9997 2073875 Maybridge1_008094 COc1ccccc1NC(=O)NCCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H21 compound treatment 861933.0 339000.0 0.48 903906.0 355000.0 0.5 0.6913 0.9999 2073876 Maybridge1_008095 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)CSCc3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H22 compound treatment 857296.0 334000.0 0.48 859187.0 311000.0 0.43 0.6425 0.9989 2073877 Maybridge1_008096 CC(C)(C)c1cc(n(n1)c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H23 mock treatment 861726.0 339000.0 0.48 879103.0 330000.0 0.46 0.6666 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 H24 mock treatment 94464.0 -428000.0 -0.61 134456.0 -414000.0 -0.58 -0.8393 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I01 compound treatment 791611.0 269000.0 0.38 795739.0 247000.0 0.34 0.5139 0.9987 2073878 Maybridge1_008097 COc1ccc(NC(=O)OC(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I02 compound treatment 793947.0 271000.0 0.39 845044.0 296000.0 0.41 0.5649 0.9994 2073879 Maybridge1_008098 Cc1noc(C)c1C(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I03 compound treatment 856626.0 334000.0 0.47 885528.0 337000.0 0.47 0.6678 1.0 2073880 Maybridge1_008099 CC(=O)c1ccc(OCCCOc2ccc(cc2)C(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I04 compound treatment 841971.0 319000.0 0.45 893096.0 344000.0 0.48 0.6606 0.9996 1396305 Maybridge1_008100 COc1cc(CNS(=O)(=O)c2c(C)noc2C)cc(OC)c1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I05 compound treatment 870991.0 348000.0 0.5 897554.0 349000.0 0.49 0.6942 1.0 2073881 Maybridge1_008101 [O-][N+](=O)c1ccc(Sc2ccccc2)nc1Sc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I06 compound treatment 827874.0 305000.0 0.43 864101.0 315000.0 0.44 0.6178 1.0 2073882 Maybridge1_008102 Cc1ccc(cc1)C(=O)C2CCN(CC2)c3ccc(cn3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I07 compound treatment 870984.0 348000.0 0.5 971905.0 423000.0 0.59 0.7675 0.9962 2073883 Maybridge1_008103 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I08 compound treatment 860205.0 337000.0 0.48 925204.0 377000.0 0.53 0.7106 0.999 2073884 Maybridge1_008104 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)C3CCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I09 compound treatment 799329.0 276000.0 0.39 918593.0 370000.0 0.52 0.6428 0.991 2073885 Maybridge1_008105 Fc1ccc(NC(=S)NNC(=O)c2ccc[nH]2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I10 compound treatment 891852.0 369000.0 0.52 928566.0 380000.0 0.53 0.7457 1.0 2073886 Maybridge1_008106 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(Sc3ccccc3)nc2Sc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I11 compound treatment 898088.0 375000.0 0.53 914895.0 366000.0 0.51 0.7385 0.9998 2073887 Maybridge1_008107 CN(C)c1ccc(/C=C(\C#N)/S(=O)(=O)C)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I12 compound treatment 866186.0 343000.0 0.49 881382.0 333000.0 0.46 0.6734 0.9997 2073888 Maybridge1_008108 Cc1noc(C)c1C(=O)NNC(=O)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I13 compound treatment 908995.0 386000.0 0.55 915319.0 367000.0 0.51 0.7499 0.9994 2073889 Maybridge1_008109 Cc1ccc(I)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I14 compound treatment 846371.0 324000.0 0.46 900870.0 352000.0 0.49 0.6727 0.9995 2073890 Maybridge1_008110 Cc1onc(c1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I15 compound treatment 953272.0 430000.0 0.61 918280.0 370000.0 0.52 0.7973 0.9963 1067691 Maybridge1_008111 Nc1ncnc2oc(nc12)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I16 compound treatment 875557.0 353000.0 0.5 900543.0 352000.0 0.49 0.7017 0.9999 2073891 Maybridge1_008112 CS(=O)(=O)N1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I17 compound treatment 933377.0 411000.0 0.58 940395.0 392000.0 0.55 0.7991 0.9994 2073892 Maybridge1_008113 Brc1cc(Br)cc(c1)C(=O)NC(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I18 compound treatment 873568.0 351000.0 0.5 893278.0 345000.0 0.48 0.6925 0.9998 2073893 Maybridge1_008114 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I19 compound treatment 937501.0 415000.0 0.59 927541.0 379000.0 0.53 0.7906 0.9985 2073894 Maybridge1_008115 Cc1noc(C)c1C(=O)Nc2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I20 compound treatment 913777.0 391000.0 0.56 887149.0 338000.0 0.47 0.7269 0.9967 2073895 Maybridge1_008116 CC(C)c1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I21 compound treatment 894728.0 372000.0 0.53 886651.0 338000.0 0.47 0.7073 0.9984 1584969 Maybridge1_008117 Cc1cc(NC(=O)c2c(C)noc2C)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I22 compound treatment 881575.0 359000.0 0.51 853514.0 305000.0 0.43 0.6614 0.9959 2073896 Maybridge1_008118 FC(F)(F)c1cnc(N2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I23 mock treatment 898683.0 376000.0 0.53 857714.0 309000.0 0.43 0.6827 0.9943 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 I24 mock treatment 127709.0 -395000.0 -0.56 125750.0 -423000.0 -0.59 -0.8144 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J01 compound treatment 775674.0 253000.0 0.36 820884.0 272000.0 0.38 0.5227 0.9996 2073897 Maybridge1_008119 FC(F)(F)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J02 compound treatment 764819.0 242000.0 0.34 807878.0 259000.0 0.36 0.499 0.9997 1470614 Maybridge1_008120 COc1cccc(c1)C(=O)Oc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J03 compound treatment 799608.0 277000.0 0.39 918953.0 370000.0 0.52 0.6435 0.991 2073898 Maybridge1_008121 FC(F)(F)c1ccc(cc1)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J04 compound treatment 790075.0 267000.0 0.38 863900.0 315000.0 0.44 0.5796 0.9974 2073899 Maybridge1_008122 FC(F)(F)c1ccc(nc1)N2CCN(CC2)C(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J05 compound treatment 811659.0 289000.0 0.41 941073.0 392000.0 0.55 0.6774 0.99 2073900 Maybridge1_008123 CC(C)(C)C(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J06 compound treatment 832729.0 310000.0 0.44 878168.0 329000.0 0.46 0.6366 0.9998 2073901 Maybridge1_008124 FC(F)(F)Oc1ccc(cc1)n2cccc2/C=C(\C#N)/S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J07 compound treatment 852843.0 330000.0 0.47 935385.0 387000.0 0.54 0.7132 0.9976 1147308 Maybridge1_008125 O=C(N1CCCCC1)C2(CC3CC4CC(C3)C2)C4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J08 compound treatment 840337.0 318000.0 0.45 863923.0 315000.0 0.44 0.6302 0.9999 2073902 Maybridge1_008126 CC(C)(C)c1ccc(cc1)C(=O)NCCSCc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J09 compound treatment 870410.0 348000.0 0.49 957963.0 409000.0 0.57 0.7531 0.9974 2073903 Maybridge1_008127 CC(C)c1ccccc1NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J10 compound treatment 803660.0 281000.0 0.4 839220.0 291000.0 0.41 0.5689 1.0 2073904 Maybridge1_008128 Fc1cccc(F)c1C(=O)Nc2ccccc2SCc3noc(n3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J11 compound treatment 839366.0 317000.0 0.45 929138.0 380000.0 0.53 0.6935 0.9966 2073905 Maybridge1_008129 COc1cccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J12 compound treatment 830100.0 307000.0 0.44 924026.0 375000.0 0.52 0.6791 0.996 1164375 Maybridge1_008130 COc1ccc(cc1)C2N(CCc3sccc23)C(=O)c4ccc(F)cc4F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J13 compound treatment 885342.0 363000.0 0.52 921495.0 373000.0 0.52 0.7322 1.0 2073906 Maybridge1_008131 FC(F)(F)c1cccnc1N2CCN(CC2)c3ccc(C#N)cn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J14 compound treatment 863637.0 341000.0 0.48 954866.0 406000.0 0.57 0.7433 0.997 2073907 Maybridge1_008132 COC(=O)c1cc(/C=N/NC(=O)c2cccnc2)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J15 compound treatment 866590.0 344000.0 0.49 924450.0 376000.0 0.52 0.7163 0.9994 2073908 Maybridge1_008133 CCc1cc2c(cc1c3csc(n3)c4ccc(F)cc4)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J16 compound treatment 828597.0 306000.0 0.43 907167.0 358000.0 0.5 0.661 0.9976 2073909 Maybridge1_008134 Cc1cc(C)c(CSCCNC(=O)Nc2ccc(cc2)C(F)(F)F)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J17 compound treatment 889938.0 367000.0 0.52 906154.0 357000.0 0.5 0.7217 0.9997 2073910 Maybridge1_008135 CC(C)(C)c1ccc(OCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J18 compound treatment 863306.0 340000.0 0.48 866777.0 318000.0 0.44 0.6561 0.999 2073911 Maybridge1_008136 Cc1ccc(c(NC(=O)Nc2ccccc2C(F)(F)F)c1)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J19 compound treatment 790949.0 268000.0 0.38 906273.0 358000.0 0.5 0.6223 0.9912 2073912 Maybridge1_008137 [O-][N+](=O)c1cccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J20 compound treatment 870803.0 348000.0 0.49 911191.0 363000.0 0.51 0.7074 0.9999 2073913 Maybridge1_008138 CC(C)Cc1ccc(cc1)C(C)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J21 compound treatment 817922.0 295000.0 0.42 893022.0 344000.0 0.48 0.6363 0.9977 2073914 Maybridge1_008139 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)CSc3ccc(Cl)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J22 compound treatment 836196.0 313000.0 0.45 877897.0 329000.0 0.46 0.6398 0.9999 2073915 Maybridge1_008140 CC(C)(C)c1cc(n(n1)c2ccc(/N=C\c3cc(Br)cc(Br)c3O)cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J23 mock treatment 877896.0 355000.0 0.5 883932.0 335000.0 0.47 0.6877 0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 J24 mock treatment 132707.0 -390000.0 -0.55 120458.0 -428000.0 -0.6 -0.8146 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K01 compound treatment 773636.0 251000.0 0.36 778739.0 230000.0 0.32 0.4791 0.9986 2073916 Maybridge1_008141 CC(C)(C)OC(=O)Nc1ccc(cc1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K02 compound treatment 784975.0 262000.0 0.37 812239.0 264000.0 0.37 0.5235 1.0 2073917 Maybridge1_008142 COC(=O)c1ccc(CSc2ccc(cn2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K03 compound treatment 806223.0 283000.0 0.4 881309.0 333000.0 0.46 0.613 0.9975 2073918 Maybridge1_008143 OC(=O)C1CC=CCC1c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K04 compound treatment 832414.0 310000.0 0.44 871448.0 323000.0 0.45 0.6296 0.9999 2073919 Maybridge1_008144 COc1cc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K05 compound treatment 841832.0 319000.0 0.45 841421.0 293000.0 0.41 0.6095 0.9986 2073920 Maybridge1_008145 CCN(CC)c1ccc([N+](=O)[O-])c(n1)N(CC)CC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K06 compound treatment 837038.0 314000.0 0.45 815621.0 267000.0 0.37 0.5792 0.9959 2073921 Maybridge1_008146 Cc1c(C)c(C)c(C(=O)C2CCN(CC2)c3ccc(cn3)[N+](=O)[O-])c(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K07 compound treatment 864712.0 342000.0 0.49 891103.0 342000.0 0.48 0.6815 1.0 2073922 Maybridge1_008147 COc1ccc([N+](=O)[O-])c(OC)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K08 compound treatment 855609.0 333000.0 0.47 862056.0 313000.0 0.44 0.6437 0.9992 2073923 Maybridge1_008148 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K09 compound treatment 856947.0 334000.0 0.48 895681.0 347000.0 0.48 0.6782 1.0 2073924 Maybridge1_008149 Clc1cc(Cl)cc(NC(=O)NNC(=O)c2ccc[nH]2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K10 compound treatment 846081.0 323000.0 0.46 872660.0 324000.0 0.45 0.6446 1.0 2073925 Maybridge1_008150 COc1cc(Br)cc(/C=N/c2ccc(Sc3ccccc3)nc2Sc4ccccc4)c1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K11 compound treatment 856961.0 334000.0 0.48 878447.0 330000.0 0.46 0.6612 0.9999 2073926 Maybridge1_008151 Nc1ccccc1Sc2nc(Sc3ccccc3N)c(cc2C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K12 compound treatment 854239.0 331000.0 0.47 857181.0 308000.0 0.43 0.6375 0.999 2073927 Maybridge1_008152 COc1ccc(cc1)C(=O)NNC(=O)c2c(C)noc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K13 compound treatment 913596.0 391000.0 0.56 867766.0 319000.0 0.45 0.7076 0.9939 2073928 Maybridge1_008153 [O-][N+](=O)c1ccc(Oc2cc(cc(c2)C(F)(F)F)C(F)(F)F)nc1Oc3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K14 compound treatment 848094.0 325000.0 0.46 848282.0 300000.0 0.42 0.6225 0.9987 2073929 Maybridge1_008154 Cc1noc(C)c1C(=O)NNC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K15 compound treatment 918462.0 396000.0 0.56 883276.0 335000.0 0.47 0.7278 0.9957 2073930 Maybridge1_008155 CN1CCN(CC1)c2ccccc2/C=C(/C#N)\S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K16 compound treatment 816187.0 293000.0 0.42 852851.0 304000.0 0.42 0.595 1.0 2073931 Maybridge1_008156 Cc1noc(C)c1c2nc(no2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K17 compound treatment 852098.0 329000.0 0.47 925301.0 377000.0 0.53 0.7025 0.9984 2073932 Maybridge1_008157 Cc1c(cnn1c2ccc(N)cc2)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K18 compound treatment 888821.0 366000.0 0.52 878552.0 330000.0 0.46 0.6933 0.9981 2073933 Maybridge1_008158 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)Nc3cccc4ccccc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K19 compound treatment 881060.0 358000.0 0.51 889986.0 341000.0 0.48 0.6968 0.9994 1261356 Maybridge1_008159 COc1ccc(NC(=O)c2c(C)noc2C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K20 compound treatment 867057.0 344000.0 0.49 845141.0 296000.0 0.41 0.6385 0.9965 2073934 Maybridge1_008160 Cc1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K21 compound treatment 900190.0 377000.0 0.54 901426.0 353000.0 0.49 0.7273 0.9991 1733003 Maybridge1_008161 Cc1noc(C)c1C(=O)Nc2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K22 compound treatment 856355.0 334000.0 0.47 851437.0 303000.0 0.42 0.634 0.9983 2073935 Maybridge1_008162 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K23 mock treatment 890340.0 368000.0 0.52 859640.0 311000.0 0.43 0.6762 0.9957 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 K24 mock treatment 83222.0 -440000.0 -0.63 145583.0 -403000.0 -0.56 -0.8396 -0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L01 compound treatment 745612.0 223000.0 0.32 801946.0 253000.0 0.35 0.4738 0.9985 2073936 Maybridge1_008163 CCOc1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L02 compound treatment 767682.0 245000.0 0.35 836458.0 288000.0 0.4 0.53 0.9975 1657471 Maybridge1_008164 Clc1ccc(cc1)C(=O)Oc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L03 compound treatment 827199.0 304000.0 0.43 867229.0 319000.0 0.44 0.6202 0.9999 1711782 Maybridge1_008165 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L04 compound treatment 759171.0 236000.0 0.34 864170.0 315000.0 0.44 0.5488 0.9912 1423636 Maybridge1_008166 Cc1c(noc1c2c(Cl)cccc2Cl)C(=O)Oc3cccc4cccnc34 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L05 compound treatment 837168.0 314000.0 0.45 900534.0 352000.0 0.49 0.6631 0.9989 2073937 Maybridge1_008167 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)Nc3cccc(Br)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L06 compound treatment 785570.0 263000.0 0.37 855761.0 307000.0 0.43 0.567 0.9977 2073938 Maybridge1_008168 COC(=O)c1cc(/C=C(\C#N)/S(=O)(=O)c2ccccc2)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L07 compound treatment 831023.0 308000.0 0.44 892815.0 344000.0 0.48 0.6493 0.999 2073939 Maybridge1_008169 Cc1cccc(c1)C(=O)Nc2ccc(nc2)N3CCN(CC3)c4ccc(cn4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L08 compound treatment 778997.0 256000.0 0.36 882526.0 334000.0 0.47 0.5868 0.9926 2073940 Maybridge1_008170 Clc1ccc(CSCCNC(=O)c2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L09 compound treatment 855253.0 332000.0 0.47 853334.0 305000.0 0.42 0.6347 0.9986 1456244 Maybridge1_008171 COc1ccccc1N2CCN(CC2)C(=O)Nc3cccc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L10 compound treatment 844719.0 322000.0 0.46 890223.0 342000.0 0.48 0.6605 0.9998 2073941 Maybridge1_008172 CCOC(=O)c1c(C)nn(c1C)c2ccc(NC(=O)Nc3ccc(cc3)C(C)(C)C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L11 compound treatment 846296.0 323000.0 0.46 904872.0 356000.0 0.5 0.6765 0.9993 2073942 Maybridge1_008173 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)Nc3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L12 compound treatment 826244.0 303000.0 0.43 856004.0 307000.0 0.43 0.6082 1.0 2073943 Maybridge1_008174 Cc1nnsc1C(=O)Nc2ccccc2SCc3noc(n3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L13 compound treatment 854013.0 331000.0 0.47 876629.0 328000.0 0.46 0.6564 0.9999 2073944 Maybridge1_008175 CCOc1ccccc1NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L14 compound treatment 846266.0 323000.0 0.46 870637.0 322000.0 0.45 0.6427 0.9999 2073945 Maybridge1_008176 COC(=O)c1cc(/C=N/NC(=S)NC(C)(C)C)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L15 compound treatment 843974.0 321000.0 0.46 903171.0 354000.0 0.49 0.6725 0.9992 2073946 Maybridge1_008177 CCc1cc2c(cc1c3csc(n3)c4ccc(cc4)C(C)(C)C)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L16 compound treatment 833382.0 311000.0 0.44 865751.0 317000.0 0.44 0.625 1.0 2073947 Maybridge1_008178 Cc1cc(C)c(CSCCNC(=O)Nc2cccc(Cl)c2C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L17 compound treatment 877712.0 355000.0 0.5 902404.0 354000.0 0.49 0.7057 0.9999 2073948 Maybridge1_008179 FC(F)(F)c1cnc(N2CCN(CC2)C(=O)COc3ccc(Cl)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L18 compound treatment 818338.0 296000.0 0.42 853832.0 305000.0 0.43 0.5981 1.0 2073949 Maybridge1_008180 Fc1cccc(Cl)c1CSCCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L19 compound treatment 834441.0 312000.0 0.44 894196.0 346000.0 0.48 0.6541 0.9991 2073950 Maybridge1_008181 CC(C)C(=O)Nc1ccc(nc1)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L20 compound treatment 833843.0 311000.0 0.44 868765.0 320000.0 0.45 0.6284 1.0 2073951 Maybridge1_008182 Cc1ccc(cc1)C(=O)NCCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L21 compound treatment 867828.0 345000.0 0.49 897896.0 349000.0 0.49 0.6913 1.0 2073952 Maybridge1_008183 CC(C)Cc1ccc(cc1)C(C)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L22 compound treatment 789474.0 267000.0 0.38 845177.0 296000.0 0.41 0.5605 0.9991 2073953 Maybridge1_008184 Cc1cc(C)c(CSCCNC2=CC(=O)CC(C2)c3ccc(Cl)cc3)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L23 mock treatment 778043.0 255000.0 0.36 857714.0 309000.0 0.43 0.5614 0.9963 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 L24 mock treatment 150445.0 -372000.0 -0.53 138836.0 -410000.0 -0.57 -0.7787 -0.9993 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M01 compound treatment 781658.0 259000.0 0.37 758969.0 210000.0 0.29 0.4676 0.9937 2073954 Maybridge1_008185 CCOC(=O)N/N=C/c1csnn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M02 compound treatment 761164.0 238000.0 0.34 762487.0 214000.0 0.3 0.4505 0.998 2073955 Maybridge1_008186 Cc1noc(C)c1C(=O)Oc2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M03 compound treatment 833145.0 310000.0 0.44 820835.0 272000.0 0.38 0.5804 0.9972 2073956 Maybridge1_008187 CN(N=C(C)C)c1ncccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M04 compound treatment 801366.0 279000.0 0.4 817217.0 269000.0 0.37 0.5449 0.9996 2073957 Maybridge1_008188 COC(=O)c1ccc(CSc2ccccc2N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M05 compound treatment 837553.0 315000.0 0.45 832276.0 284000.0 0.4 0.5962 0.9981 2073958 Maybridge1_008189 OCCN1CCN(CC1)c2ccc([N+](=O)[O-])c(n2)N3CCN(CCO)CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M06 compound treatment 814266.0 291000.0 0.41 814748.0 266000.0 0.37 0.5554 0.9985 2073959 Maybridge1_008190 [O-][N+](=O)c1ccc(nc1)N2CCC(CC2)C(=O)c3ccc(F)cc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M07 compound treatment 813121.0 290000.0 0.41 856088.0 307000.0 0.43 0.5951 0.9998 1596301 Maybridge1_008191 Clc1ccc2nc(sc2c1)N3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M08 compound treatment 843280.0 320000.0 0.46 827830.0 279000.0 0.39 0.5975 0.9969 2073960 Maybridge1_008192 COC(=O)c1ccc(CSc2ccc(Cl)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M09 compound treatment 862534.0 340000.0 0.48 846029.0 297000.0 0.41 0.6348 0.9971 1409042 Maybridge1_008193 OC(=O)c1c2CCCCCc2nc3ccc(F)cc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M10 compound treatment 821876.0 299000.0 0.43 825897.0 277000.0 0.39 0.5741 0.9989 2073961 Maybridge1_008194 FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(Sc3ccccc3)nc2Sc4ccccc4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M11 compound treatment 877848.0 355000.0 0.5 870466.0 322000.0 0.45 0.6743 0.9983 2073962 Maybridge1_008195 CCN(CC)c1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M12 compound treatment 856634.0 334000.0 0.47 844586.0 296000.0 0.41 0.6275 0.9976 2073963 Maybridge1_008196 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M13 compound treatment 862688.0 340000.0 0.48 858188.0 310000.0 0.43 0.647 0.9984 2073964 Maybridge1_008197 COc1ccc(Oc2cc(ccn2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M14 compound treatment 884540.0 362000.0 0.51 842640.0 294000.0 0.41 0.6536 0.9937 2073965 Maybridge1_008198 COc1ccc(cc1)C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M15 compound treatment 887735.0 365000.0 0.52 839161.0 290000.0 0.41 0.6534 0.9925 2073966 Maybridge1_008199 NC(=S)c1cc(Br)cc(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M16 compound treatment 868681.0 346000.0 0.49 835032.0 286000.0 0.4 0.6302 0.9947 2073967 Maybridge1_008200 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M17 compound treatment 899202.0 376000.0 0.54 905016.0 356000.0 0.5 0.7299 0.9993 2073968 Maybridge1_008201 [O-][N+](=O)c1ccc(N/N=C/c2cc(Cl)cc(Cl)c2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M18 compound treatment 859028.0 336000.0 0.48 846199.0 298000.0 0.41 0.6315 0.9975 2073969 Maybridge1_008202 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)NC3CCCCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M19 compound treatment 919468.0 397000.0 0.56 878791.0 330000.0 0.46 0.7244 0.9949 1415355 Maybridge1_008203 Cc1noc(C)c1C(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M20 compound treatment 840147.0 317000.0 0.45 840301.0 292000.0 0.41 0.6067 0.9987 2073970 Maybridge1_008204 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)NC(=O)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M21 compound treatment 888609.0 366000.0 0.52 879679.0 331000.0 0.46 0.6942 0.9982 2073971 Maybridge1_008205 Cc1noc(C)c1C(=O)Nc2ccccc2OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M22 compound treatment 850695.0 328000.0 0.47 832965.0 284000.0 0.4 0.61 0.9967 1568151 Maybridge1_008206 COc1ccccc1N2CCN(CC2)C(=O)c3c(F)cccc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M23 mock treatment 858118.0 335000.0 0.48 830486.0 282000.0 0.39 0.6151 0.9954 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 M24 mock treatment 655903.0 133000.0 0.19 666403.0 118000.0 0.16 0.2499 0.9975 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N01 compound treatment 784720.0 262000.0 0.37 825058.0 276000.0 0.39 0.5359 0.9999 2073972 Maybridge1_008207 COC(=O)c1ccccc1NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N02 compound treatment 773767.0 251000.0 0.36 807586.0 259000.0 0.36 0.5077 1.0 1648286 Maybridge1_008208 O=C(Oc1cccc2cccnc12)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N03 compound treatment 826032.0 303000.0 0.43 888012.0 339000.0 0.47 0.6395 0.9989 1371722 Maybridge1_008209 COc1ccccc1N2CCN(CC2)C(=O)c3snnc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N04 compound treatment 783765.0 261000.0 0.37 838440.0 290000.0 0.4 0.5481 0.9991 1261145 Maybridge1_008210 CC(C)Cc1ccc(cc1)C(C)c2nnc(o2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N05 compound treatment 848058.0 325000.0 0.46 904415.0 356000.0 0.5 0.6779 0.9994 1642423 Maybridge1_008211 COc1cccc(c1)C(=O)N2CCN(CC2)c3ccccc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N06 compound treatment 790062.0 267000.0 0.38 832197.0 284000.0 0.4 0.5483 0.9998 2073973 Maybridge1_008212 COc1ccc(cc1)c2n[nH]cc2/C=N/NC(=O)c3cccc(c3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N07 compound treatment 819207.0 296000.0 0.42 902436.0 354000.0 0.49 0.6469 0.9969 2073974 Maybridge1_008213 COc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCN(CC3)c4ccc(cn4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N08 compound treatment 824037.0 301000.0 0.43 813150.0 264000.0 0.37 0.5637 0.9972 2073975 Maybridge1_008214 CC(=O)c1sc(nc1C)c2cnccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N09 compound treatment 861503.0 339000.0 0.48 853620.0 305000.0 0.43 0.6413 0.9981 1331296 Maybridge1_008215 COc1ccc(Cl)cc1NC(=O)N2CCN(CC2)c3ccccc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N10 compound treatment 830723.0 308000.0 0.44 873062.0 324000.0 0.45 0.6295 0.9999 2073976 Maybridge1_008216 CCOC(=O)c1c(C)nn(c1C)c2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N11 compound treatment 862604.0 340000.0 0.48 880883.0 332000.0 0.46 0.6693 0.9998 2073977 Maybridge1_008217 FC(F)(F)c1cccc(NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N12 compound treatment 846771.0 324000.0 0.46 891678.0 343000.0 0.48 0.664 0.9998 1232430 Maybridge1_008218 COc1ccc(NC(=O)NC(=O)C(C)c2ccc(CC(C)C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N13 compound treatment 802846.0 280000.0 0.4 874741.0 326000.0 0.45 0.6031 0.9978 1271373 Maybridge1_008219 COc1ccccc1N2CCN(CC2)C(=O)Nc3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N14 compound treatment 754150.0 231000.0 0.33 833023.0 284000.0 0.4 0.513 0.9957 2073978 Maybridge1_008220 COC(=O)c1cc(/C=N/NC(=S)NC2CC3CC2C=C3)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N15 compound treatment 860037.0 337000.0 0.48 877385.0 329000.0 0.46 0.6632 0.9997 1535191 Maybridge1_008221 COc1ccccc1N2CCN(CC2)C(=O)Nc3c(C)onc3c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N16 compound treatment 826980.0 304000.0 0.43 868359.0 320000.0 0.45 0.6211 0.9999 2073979 Maybridge1_008222 CC(C)c1cc(Br)c(NC(=O)NCCSCc2c(C)cc(C)cc2C)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N17 compound treatment 882286.0 359000.0 0.51 915710.0 367000.0 0.51 0.7234 1.0 2073980 Maybridge1_008223 CC(=O)Nc1ccc(OCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N18 compound treatment 791182.0 268000.0 0.38 864108.0 315000.0 0.44 0.5809 0.9975 2073981 Maybridge1_008224 CCc1cc2c(cc1c3csc(n3)c4cnccn4)C(C)(C)CCC2(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N19 compound treatment 869532.0 347000.0 0.49 899251.0 351000.0 0.49 0.6944 1.0 2073982 Maybridge1_008225 COc1ccccc1NC(=O)N2CCc3c([nH]c4ccccc34)C2C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N20 compound treatment 850470.0 328000.0 0.47 865611.0 317000.0 0.44 0.642 0.9997 1929721 Maybridge1_008226 COc1ccc(cc1)C(=O)NCCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N21 compound treatment 872558.0 350000.0 0.5 893469.0 345000.0 0.48 0.6917 0.9999 1503355 Maybridge1_008227 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2ccc3OCCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N22 compound treatment 829858.0 307000.0 0.44 871793.0 323000.0 0.45 0.6274 0.9999 1725517 Maybridge1_008228 Clc1ccc(cc1)C2CC(=O)C=C(C2)NCc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N23 mock treatment 863475.0 341000.0 0.48 888495.0 340000.0 0.47 0.6777 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 N24 mock treatment 657325.0 134000.0 0.19 589718.0 41000.0 0.06 0.1757 0.8801 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O01 compound treatment 778282.0 255000.0 0.36 755152.0 206000.0 0.29 0.4605 0.9934 2073983 Maybridge1_008229 CC(C)(C)OC(=O)Nc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O02 compound treatment 773679.0 251000.0 0.36 794103.0 245000.0 0.34 0.4943 0.9998 1458129 Maybridge1_008230 CC(C)(C)c1ccc(s1)C(=O)Nc2ccc(Oc3ccc(Cl)cc3Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O03 compound treatment 788674.0 266000.0 0.38 831516.0 283000.0 0.39 0.5462 0.9998 2073984 Maybridge1_008231 [O-][N+](=O)c1ccc(nc1N2CCOCC2)N3CCOCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O04 compound treatment 791702.0 269000.0 0.38 813794.0 265000.0 0.37 0.5318 0.9999 2073985 Maybridge1_008232 COC(=O)c1ccc(CC(=S)C(c2ccccc2)(c3ccccc3)c4ccccc4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O05 compound treatment 843193.0 320000.0 0.46 824051.0 275000.0 0.38 0.5937 0.9964 2073986 Maybridge1_008233 OCCSc1ccc([N+](=O)[O-])c(SCCO)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O06 compound treatment 763620.0 241000.0 0.34 804619.0 256000.0 0.36 0.4945 0.9998 2073987 Maybridge1_008234 COc1cc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O07 compound treatment 855405.0 333000.0 0.47 850807.0 302000.0 0.42 0.6324 0.9983 1282369 Maybridge1_008235 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O08 compound treatment 802145.0 279000.0 0.4 806958.0 258000.0 0.36 0.5356 0.9988 2073988 Maybridge1_008236 COc1ccc(NC(=O)c2ccc(s2)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O09 compound treatment 831724.0 309000.0 0.44 847008.0 298000.0 0.42 0.6048 0.9996 2073989 Maybridge1_008237 COc1ccc(cc1)C(=O)N/N=C/c2cccn2c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O10 compound treatment 778276.0 255000.0 0.36 820250.0 272000.0 0.38 0.5247 0.9998 1660914 Maybridge1_008238 Cc1noc(C)c1C(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O11 compound treatment 810120.0 287000.0 0.41 821862.0 273000.0 0.38 0.5583 0.9994 2073990 Maybridge1_008239 Cc1noc(C)c1C(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O12 compound treatment 806649.0 284000.0 0.4 815773.0 267000.0 0.37 0.5488 0.9992 2073991 Maybridge1_008240 Cc1noc(C)c1C(=O)O/N=C(\N)/c2cc(cc(c2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O13 compound treatment 839621.0 317000.0 0.45 812958.0 264000.0 0.37 0.5792 0.995 2073992 Maybridge1_008241 CN(C)c1cc(Cl)cc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O14 compound treatment 823285.0 300000.0 0.43 803433.0 255000.0 0.36 0.5534 0.9958 2073993 Maybridge1_008242 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O15 compound treatment 872289.0 349000.0 0.5 844032.0 295000.0 0.41 0.6427 0.9957 2073994 Maybridge1_008243 CN1CCN(CC1)c2ccccc2/C=N\Nc3cc(Cl)ccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O16 compound treatment 777329.0 254000.0 0.36 788025.0 239000.0 0.33 0.492 0.9992 2073995 Maybridge1_008244 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O17 compound treatment 887164.0 364000.0 0.52 863492.0 315000.0 0.44 0.6768 0.9966 2073996 Maybridge1_008245 Cn1cnc2cccc(F)c2c1=N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O18 compound treatment 832541.0 310000.0 0.44 808187.0 260000.0 0.36 0.5674 0.9952 2073997 Maybridge1_008246 Fc1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O19 compound treatment 884418.0 362000.0 0.51 849572.0 301000.0 0.42 0.6603 0.9949 1447262 Maybridge1_008247 Cc1noc(C)c1C(=O)Nc2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O20 compound treatment 816877.0 294000.0 0.42 848832.0 300000.0 0.42 0.5917 1.0 2073998 Maybridge1_008248 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O21 compound treatment 885390.0 363000.0 0.52 843553.0 295000.0 0.41 0.6554 0.9937 2073999 Maybridge1_008249 Cc1noc(C)c1C(=O)Oc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O22 compound treatment 835719.0 313000.0 0.44 796915.0 248000.0 0.35 0.5594 0.9923 2074000 Maybridge1_008250 FC(F)(F)c1cnc(N2CCN(CC2)C(=S)Nc3cccc(Cl)c3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O23 mock treatment 864797.0 342000.0 0.49 832477.0 284000.0 0.4 0.6237 0.9948 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 O24 mock treatment 224677.0 -298000.0 -0.42 518515.0 -30200.0 -0.04 -0.3296 -0.7735 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P01 compound treatment 745918.0 223000.0 0.32 769358.0 221000.0 0.31 0.442 0.9999 2074001 Maybridge1_008251 CN(C)c1ccc(NC(=S)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P02 compound treatment 763156.0 240000.0 0.34 796908.0 248000.0 0.35 0.4865 1.0 1382298 Maybridge1_008252 Cc1noc(C)c1C(=O)Oc2cccc3cccnc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P03 compound treatment 736648.0 214000.0 0.3 810480.0 262000.0 0.37 0.4732 0.9959 1392030 Maybridge1_008253 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3c(C)c(C)c(C)c(C)c3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P04 compound treatment 801932.0 279000.0 0.4 800091.0 251000.0 0.35 0.5286 0.9981 2074002 Maybridge1_008254 FC(F)(F)c1cccnc1N2CCN(CC2)C(=O)c3cccc(CSc4ccc(Cl)cc4)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P05 compound treatment 794652.0 272000.0 0.39 809583.0 261000.0 0.36 0.5306 0.9995 1204874 Maybridge1_008255 Clc1sc(cc1Br)S(=O)(=O)N2CCN(CC2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P06 compound treatment 755229.0 232000.0 0.33 802719.0 254000.0 0.35 0.4842 0.9994 2074003 Maybridge1_008256 COc1ccc(cc1)c2n[nH]cc2/C=N/NC(=O)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P07 compound treatment 775961.0 253000.0 0.36 817707.0 269000.0 0.38 0.5198 0.9998 2074004 Maybridge1_008257 COc1ccc(Cl)cc1NC(=O)N2CCN(CC2)c3ncccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P08 compound treatment 768232.0 245000.0 0.35 781273.0 233000.0 0.32 0.4761 0.9993 2074005 Maybridge1_008258 COc1ccccc1N2CCN(CCCCNS(=O)(=O)c3ccc(C)cc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P09 compound treatment 786349.0 264000.0 0.37 792982.0 244000.0 0.34 0.5059 0.9989 2074006 Maybridge1_008259 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P10 compound treatment 755678.0 233000.0 0.33 774953.0 226000.0 0.32 0.4573 0.9997 2074007 Maybridge1_008260 [O-][N+](=O)c1ccc(Oc2cccc3cccnc23)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P11 compound treatment 782019.0 259000.0 0.37 780509.0 232000.0 0.32 0.4893 0.9979 2074008 Maybridge1_008261 Cc1ccc(SCC(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P12 compound treatment 779777.0 257000.0 0.37 816007.0 267000.0 0.37 0.522 0.9999 2074009 Maybridge1_008262 COC(=O)c1cc(/C=C/2\CSc3ccc(Cl)cc3C2=O)cn1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P13 compound treatment 787626.0 265000.0 0.38 789203.0 241000.0 0.34 0.5035 0.9983 2074010 Maybridge1_008263 COc1ccccc1N2CCN(CC2)C(=O)Nc3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P14 compound treatment 784325.0 261000.0 0.37 800569.0 252000.0 0.35 0.5114 0.9996 1463730 Maybridge1_008264 O=C(Nc1ccc(Oc2cccc3cccnc23)cc1)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P15 compound treatment 786388.0 264000.0 0.37 823334.0 275000.0 0.38 0.5359 0.9999 1653299 Maybridge1_008265 COc1ccccc1N2CCN(CC2)C(=S)Nc3cc(OC)c(Cl)cc3OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P16 compound treatment 789577.0 267000.0 0.38 820933.0 272000.0 0.38 0.5367 1.0 1491039 Maybridge1_008266 CC(C)Cc1ccc(cc1)C(C)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P17 compound treatment 799065.0 276000.0 0.39 837860.0 289000.0 0.4 0.563 0.9999 2074011 Maybridge1_008267 CN(C)c1ccc(/C=C/2\C(=O)ON=C2c3ccccc3)cc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P18 compound treatment 799482.0 277000.0 0.39 833973.0 285000.0 0.4 0.5595 1.0 1336300 Maybridge1_008268 OCc1ccccc1N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P19 compound treatment 835661.0 313000.0 0.44 853084.0 304000.0 0.42 0.6148 0.9997 2074012 Maybridge1_008269 C(Sc1ccccn1)c2nnn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P20 compound treatment 840879.0 318000.0 0.45 835495.0 287000.0 0.4 0.6027 0.9981 2074013 Maybridge1_008270 Oc1c(Cl)cc(Cl)cc1/C=N/CCSCc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P21 compound treatment 801486.0 279000.0 0.4 818615.0 270000.0 0.38 0.5464 0.9997 1487225 Maybridge1_008271 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P22 compound treatment 818671.0 296000.0 0.42 821038.0 272000.0 0.38 0.5661 0.9987 2074014 Maybridge1_008272 COc1cc(OC)c(C=C2C(=O)OC(C)(C)OC2=O)cc1OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P23 mock treatment 772930.0 250000.0 0.36 793073.0 244000.0 0.34 0.4925 0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.564 P24 mock treatment 263727.0 -259000.0 -0.37 545114.0 -3570.0 0.0 -0.2641 -0.7166 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A01 compound treatment 744084.0 211000.0 0.3 773865.0 212000.0 0.3 0.4214 1.0 2074015 Maybridge1_008273 Clc1ccccc1CSCCNC2=CC(=O)CC(C2)c3ccc4OCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A02 compound treatment 721441.0 188000.0 0.27 784459.0 223000.0 0.31 0.4091 0.9972 2074016 Maybridge1_008274 COc1ccc(Oc2ccc(cc2c3nc(no3)c4ccc(cc4)C(F)(F)F)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A03 compound treatment 722872.0 190000.0 0.27 817673.0 256000.0 0.36 0.4433 0.9904 1638111 Maybridge1_008275 OC(=O)C1CN(Cc2ccc3OCOc3c2)C(=O)C1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A04 compound treatment 734675.0 201000.0 0.29 815181.0 254000.0 0.35 0.4527 0.9945 2074017 Maybridge1_008276 Cc1c(sc2ccccc12)c3csc(n3)c4ccc(cc4)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A05 compound treatment 751491.0 218000.0 0.31 836950.0 275000.0 0.38 0.4911 0.9944 2074018 Maybridge1_008277 COC(=O)c1c(C)n(C)c(C)c1C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A06 compound treatment 798860.0 266000.0 0.38 863621.0 302000.0 0.42 0.565 0.9985 1300315 Maybridge1_008278 Cc1c(sc2ccccc12)c3csc(CC#N)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A07 compound treatment 816512.0 283000.0 0.4 853982.0 292000.0 0.41 0.5733 1.0 1334149 Maybridge1_008279 Cc1oc(cc1C(=O)CC#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A08 compound treatment 786349.0 253000.0 0.36 839373.0 278000.0 0.39 0.5285 0.9993 2074019 Maybridge1_008280 CCn1nc(C)c(Br)c1c2nc(no2)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A09 compound treatment 781234.0 248000.0 0.35 848795.0 287000.0 0.4 0.5327 0.998 2074020 Maybridge1_008281 COc1ccc(cc1)c2cc(C(=O)O)c(o2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A10 compound treatment 789979.0 257000.0 0.37 862820.0 301000.0 0.42 0.5553 0.9976 2074021 Maybridge1_008282 COc1ccc(Oc2ccc(cc2c3nc(no3)c4cnccn4)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A11 compound treatment 765218.0 232000.0 0.33 862087.0 301000.0 0.42 0.5297 0.993 1640175 Maybridge1_008283 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)Nc4ccccc4C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A12 compound treatment 802898.0 270000.0 0.38 866272.0 305000.0 0.42 0.5717 0.9987 2074022 Maybridge1_008284 Cc1ccc(cc1C)n2nc(cc2NC(=O)Nc3ccc(OC(F)(F)F)cc3)c4ccc(OC(F)(F)F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A13 compound treatment 797330.0 264000.0 0.38 858271.0 297000.0 0.41 0.5582 0.9988 1726197 Maybridge1_008285 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3ccc4OCCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A14 compound treatment 802825.0 270000.0 0.38 890962.0 329000.0 0.46 0.596 0.996 2074023 Maybridge1_008286 Cc1oc(cc1C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A15 compound treatment 804089.0 271000.0 0.39 885147.0 324000.0 0.45 0.5915 0.9969 1625077 Maybridge1_008287 Cc1nc(cs1)c2ccc3OCCCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A16 compound treatment 820927.0 288000.0 0.41 866901.0 305000.0 0.43 0.5905 0.9998 1700251 Maybridge1_008288 COc1ccc(C)cc1NC(=O)c2cc(oc2C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A17 compound treatment 816388.0 283000.0 0.4 877178.0 316000.0 0.44 0.596 0.999 2074024 Maybridge1_008289 Fc1ccc(cc1F)c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A18 compound treatment 795798.0 263000.0 0.37 869939.0 308000.0 0.43 0.5682 0.9975 1421877 Maybridge1_008290 CN(C)S(=O)(=O)c1cc(C(=O)O)c(C)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A19 compound treatment 824332.0 291000.0 0.41 860988.0 299000.0 0.42 0.588 1.0 2074025 Maybridge1_008291 Cc1c(cc(c2ccccc2)n1CCSCc3c(Cl)cccc3Cl)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A20 compound treatment 789403.0 256000.0 0.36 831480.0 270000.0 0.38 0.5238 0.9999 2074026 Maybridge1_008292 CCOC(=O)c1cc(C)nc(Sc2ccccc2)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A21 compound treatment 758248.0 225000.0 0.32 819192.0 258000.0 0.36 0.4804 0.9983 1122468 Maybridge1_008293 COc1ccc(OCc2nc(cs2)c3ccc(F)c(F)c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A22 compound treatment 757861.0 225000.0 0.32 804418.0 243000.0 0.34 0.4654 0.9996 2074027 Maybridge1_008294 COc1c(Br)cc(cc1Br)/C(=N/OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A23 mock treatment 745474.0 212000.0 0.3 773060.0 211000.0 0.29 0.422 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 A24 mock treatment 135441.0 -398000.0 -0.57 140093.0 -421000.0 -0.59 -0.8156 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B01 compound treatment 754285.0 221000.0 0.31 800104.0 239000.0 0.33 0.4576 0.9996 1375743 Maybridge1_008295 Cc1cc(nn1c2c(Cl)cc(Cl)cc2Cl)C(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B02 compound treatment 749141.0 216000.0 0.31 847276.0 286000.0 0.4 0.4989 0.9917 2074028 Maybridge1_008296 CC(C)Sc1c(Cl)cccc1NC(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B03 compound treatment 795071.0 262000.0 0.37 918262.0 357000.0 0.5 0.6151 0.9898 2074029 Maybridge1_008297 CC(C)(C)c1ccc(cc1)c2nnc(S)n2c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B04 compound treatment 784887.0 252000.0 0.36 897347.0 336000.0 0.47 0.5842 0.9912 2074030 Maybridge1_008298 Oc1nnc(Sc2ncc(s2)[N+](=O)[O-])n1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B05 compound treatment 822962.0 290000.0 0.41 923806.0 362000.0 0.51 0.6486 0.9949 2074031 Maybridge1_008299 CC(C)(C)c1ccc(cc1)n2c(SCc3ccc(Cl)cc3)nnc2c4ccccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B06 compound treatment 811782.0 279000.0 0.4 891703.0 330000.0 0.46 0.6057 0.9972 2074032 Maybridge1_008300 NNC(=O)c1csc(n1)c2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B07 compound treatment 843030.0 310000.0 0.44 975638.0 414000.0 0.58 0.7199 0.9911 2074033 Maybridge1_008301 Clc1ccc(NC(=O)Oc2ccc(cc2)C3SCCS3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B08 compound treatment 855246.0 322000.0 0.46 943206.0 382000.0 0.53 0.7002 0.9972 2074034 Maybridge1_008302 CCOC(=O)c1sc(nc1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B09 compound treatment 924760.0 392000.0 0.56 1014337.0 453000.0 0.63 0.8403 0.998 2074035 Maybridge1_008303 [O-][N+](=O)c1ccc(o1)C(=O)NC(=S)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B10 compound treatment 1098581.0 565000.0 0.8 1231944.0 670000.0 0.93 1.2297 0.9972 1356228 Maybridge1_008304 CCCS(=O)(=O)c1c(C)c(C)n(CCc2ccc(Cl)cc2)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B11 compound treatment 874145.0 341000.0 0.48 970879.0 409000.0 0.57 0.7465 0.9967 2074036 Maybridge1_008305 N/C(=N\O)/c1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B12 compound treatment 855982.0 323000.0 0.46 946834.0 385000.0 0.54 0.7045 0.9969 2074037 Maybridge1_008306 Cc1nc(cs1)c2nnc(S)n2c3cccc(F)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B13 compound treatment 868906.0 336000.0 0.48 963017.0 401000.0 0.56 0.7335 0.9969 2074038 Maybridge1_008307 Cc1cc(no1)C(=O)NNC(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B14 compound treatment 863530.0 330000.0 0.47 956104.0 395000.0 0.55 0.7213 0.9969 1681297 Maybridge1_008308 NNC(=O)c1ccc(Oc2ccc(cc2)C3SCCS3)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B15 compound treatment 908089.0 375000.0 0.53 999118.0 438000.0 0.61 0.8085 0.9977 2074039 Maybridge1_008309 NNC(=O)COc1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B16 compound treatment 867821.0 335000.0 0.48 968435.0 407000.0 0.57 0.7377 0.9962 2074040 Maybridge1_008310 CCOC(=O)c1sc(nc1O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B17 compound treatment 903762.0 371000.0 0.53 976653.0 415000.0 0.58 0.782 0.9989 2074041 Maybridge1_008311 COC(CNC(=O)COc1ccc(Cl)cc1Cl)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B18 compound treatment 860205.0 327000.0 0.47 943842.0 382000.0 0.53 0.7058 0.9977 2074042 Maybridge1_008312 NC(=S)c1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B19 compound treatment 874525.0 341000.0 0.49 964645.0 403000.0 0.56 0.7407 0.9973 2074043 Maybridge1_008313 FC(F)(F)c1ccc(cc1)C(=O)NC(=O)OCC#C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B20 compound treatment 829239.0 296000.0 0.42 915720.0 354000.0 0.49 0.647 0.9968 1462880 Maybridge1_008314 OC(=O)CCn1c(=O)oc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B21 compound treatment 827064.0 294000.0 0.42 951450.0 390000.0 0.54 0.68 0.9915 2074044 Maybridge1_008315 COc1ccc(Oc2ccc(cc2[N+](=O)[O-])/C(=N/O)/N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B22 compound treatment 819589.0 286000.0 0.41 885853.0 324000.0 0.45 0.6078 0.9986 1195100 Maybridge1_008316 NNC(=O)c1csc(n1)c2ccc(cc2)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B23 mock treatment 820690.0 287000.0 0.41 885926.0 324000.0 0.45 0.609 0.9987 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 B24 mock treatment 148768.0 -384000.0 -0.55 142671.0 -419000.0 -0.58 -0.7997 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C01 compound treatment 688110.0 155000.0 0.22 740990.0 179000.0 0.25 0.3327 0.998 2074045 Maybridge1_008317 CC(C)(C)c1ccc(CSCCNC2=CC(=O)CC(C2)c3ccc4OCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C02 compound treatment 701034.0 168000.0 0.24 757677.0 196000.0 0.27 0.3622 0.9977 2074046 Maybridge1_008318 COC(=O)CSCCc1nc(cs1)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C03 compound treatment 720343.0 187000.0 0.27 832520.0 271000.0 0.38 0.4554 0.9853 2074047 Maybridge1_008319 CN(NC(=O)c1ccncc1Cl)c2cnc3ccccc3n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C04 compound treatment 711626.0 178000.0 0.25 823517.0 262000.0 0.37 0.4378 0.9841 2074048 Maybridge1_008320 FC(F)(F)c1ccc(cc1)c2csc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C05 compound treatment 745014.0 212000.0 0.3 852709.0 291000.0 0.41 0.5001 0.9892 2074049 Maybridge1_008321 CCOC(=O)c1cc(C)n(c1C)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C06 compound treatment 752152.0 219000.0 0.31 798206.0 237000.0 0.33 0.4536 0.9996 2074050 Maybridge1_008322 Cc1c(cc(n1CCSCc2c(F)cccc2Cl)C(C)(C)C)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C07 compound treatment 750044.0 217000.0 0.31 820132.0 259000.0 0.36 0.4731 0.997 2074051 Maybridge1_008323 Cc1cc(C(=O)N)c(o1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C08 compound treatment 763675.0 230000.0 0.33 852016.0 290000.0 0.41 0.5182 0.9945 2074052 Maybridge1_008324 Cc1ccc(cc1)c2noc(n2)c3ccc(F)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C09 compound treatment 790851.0 258000.0 0.37 868360.0 307000.0 0.43 0.5617 0.997 2074053 Maybridge1_008325 OC(=O)c1cc(oc1C(F)(F)F)c2cccc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C10 compound treatment 790489.0 257000.0 0.37 850531.0 289000.0 0.4 0.5437 0.9988 2074054 Maybridge1_008326 Fc1ccc(c2nc(no2)c3ccccc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C11 compound treatment 791273.0 258000.0 0.37 890748.0 329000.0 0.46 0.5842 0.9938 1598391 Maybridge1_008327 COc1cccc(NC(=O)c2cc(c3ccccc3)n(c2C)c4ccccc4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C12 compound treatment 784216.0 251000.0 0.36 853914.0 292000.0 0.41 0.5407 0.9978 2074055 Maybridge1_008328 Cc1ccc(cc1C)n2nc(cc2NC(=O)Nc3ccccc3C#N)c4ccc(OC(F)(F)F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C13 compound treatment 804826.0 272000.0 0.39 882526.0 321000.0 0.45 0.5897 0.9973 2074056 Maybridge1_008329 Cc1ccc(c2csc(n2)c3ccc(cc3)C(C)(C)C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C14 compound treatment 797264.0 264000.0 0.38 865038.0 303000.0 0.42 0.5648 0.9982 2074057 Maybridge1_008330 Cc1oc(cc1C(=O)N2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C15 compound treatment 825848.0 293000.0 0.42 899796.0 338000.0 0.47 0.6278 0.998 2074058 Maybridge1_008331 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C16 compound treatment 793236.0 260000.0 0.37 880771.0 319000.0 0.45 0.5763 0.9957 1420936 Maybridge1_008332 COc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc(I)cc3F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C17 compound treatment 798265.0 265000.0 0.38 896954.0 335000.0 0.47 0.5973 0.9943 2074059 Maybridge1_008333 FC(F)(F)c1ccc(Oc2ccc(cc2)c3nc(cs3)c4ccc5OCCCOc5c4)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C18 compound treatment 765351.0 232000.0 0.33 844386.0 283000.0 0.39 0.5124 0.9961 2074060 Maybridge1_008334 FC(F)(F)c1cc(n[nH]1)c2ccc3ccccc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C19 compound treatment 795746.0 263000.0 0.37 877561.0 316000.0 0.44 0.5756 0.9966 2074061 Maybridge1_008335 FC(F)(F)c1ccc(cc1)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C20 compound treatment 777074.0 244000.0 0.35 844630.0 283000.0 0.39 0.5244 0.9979 2074062 Maybridge1_008336 CCOC(=O)c1c(Cl)c(nc(Sc2ccccc2)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C21 compound treatment 804022.0 271000.0 0.39 856826.0 295000.0 0.41 0.5635 0.9994 1343867 Maybridge1_008337 COc1ccc(OCc2nc(cs2)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C22 compound treatment 750218.0 217000.0 0.31 821653.0 260000.0 0.36 0.4747 0.9968 2074063 Maybridge1_008338 Cn1c(SC(=O)Cc2cccc(c2)[N+](=O)[O-])nnc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C23 mock treatment 760511.0 227000.0 0.32 800297.0 239000.0 0.33 0.464 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 C24 mock treatment 159267.0 -374000.0 -0.53 156480.0 -405000.0 -0.56 -0.7755 -0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D01 compound treatment 731475.0 198000.0 0.28 777861.0 216000.0 0.3 0.4127 0.9994 1036975 Maybridge1_008339 Clc1ccc(OCC#N)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D02 compound treatment 716388.0 183000.0 0.26 795648.0 234000.0 0.33 0.4151 0.9937 2074064 Maybridge1_008340 [O-][N+](=O)c1cc(C#N)ccc1Oc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D03 compound treatment 772379.0 239000.0 0.34 839359.0 278000.0 0.39 0.5145 0.9979 1564721 Maybridge1_008341 Clc1ccc(COc2ccc(C#N)cc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D04 compound treatment 761422.0 228000.0 0.32 869681.0 308000.0 0.43 0.5334 0.9904 2074065 Maybridge1_008342 [O-][N+](=O)c1cnc(Sc2nnc([nH]2)c3ccc(Cl)cc3)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D05 compound treatment 827426.0 294000.0 0.42 929747.0 368000.0 0.51 0.659 0.9948 2074066 Maybridge1_008343 N/C(=N\O)/Cc1cccc2ccccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D06 compound treatment 813772.0 281000.0 0.4 872242.0 311000.0 0.43 0.5885 0.9992 1317844 Maybridge1_008344 Cc1c(C)n(Cc2cccc(C)c2C)c(N)c1S(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D07 compound treatment 811822.0 279000.0 0.4 903720.0 342000.0 0.48 0.6176 0.9957 2074067 Maybridge1_008345 [O-][N+](=O)c1ccc(OCc2c(Cl)cccc2Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D08 compound treatment 825438.0 292000.0 0.42 938649.0 377000.0 0.53 0.6658 0.9932 2074068 Maybridge1_008346 Cc1noc(c1C(=O)NN)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D09 compound treatment 939500.0 406000.0 0.58 998137.0 437000.0 0.61 0.8391 0.9997 2074069 Maybridge1_008347 [O-][N+](=O)c1ccc(o1)C(=O)NC(=S)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D10 compound treatment 839118.0 306000.0 0.44 915546.0 354000.0 0.49 0.6567 0.998 1074754 Maybridge1_008348 CCOC(=O)c1csc(C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D11 compound treatment 859379.0 326000.0 0.46 900232.0 339000.0 0.47 0.662 1.0 2074070 Maybridge1_008349 N/C(=N\OC(=O)C(Cl)Cl)/c1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D12 compound treatment 830223.0 297000.0 0.42 873143.0 312000.0 0.43 0.606 0.9999 1373540 Maybridge1_008350 NNC(=O)Cc1ccsc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D13 compound treatment 858150.0 325000.0 0.46 927113.0 366000.0 0.51 0.6873 0.9988 2074071 Maybridge1_008351 O=c1cc(CSc2ccccn2)[nH]c(=O)[nH]1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D14 compound treatment 833476.0 300000.0 0.43 907160.0 346000.0 0.48 0.6428 0.9982 2074072 Maybridge1_008352 N#CCOc1ccc(cc1)C2=NCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D15 compound treatment 886203.0 353000.0 0.5 950242.0 389000.0 0.54 0.7383 0.9993 2074073 Maybridge1_008353 Clc1cc(Cl)cc(OCC#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D16 compound treatment 842538.0 309000.0 0.44 939809.0 378000.0 0.53 0.6841 0.9959 2074074 Maybridge1_008354 CC(=O)c1sc(COc2cccc(Cl)c2)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D17 compound treatment 853250.0 320000.0 0.46 985203.0 424000.0 0.59 0.7396 0.9917 1002173 Maybridge1_008355 CCCCCCCCCCCC(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D18 compound treatment 862504.0 329000.0 0.47 957099.0 396000.0 0.55 0.7212 0.9967 2074075 Maybridge1_008356 CCOC(=O)c1sc(nc1O)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D19 compound treatment 866092.0 333000.0 0.47 983489.0 422000.0 0.59 0.7509 0.9942 2074076 Maybridge1_008357 FC(F)(F)c1ccc(cc1)C(=O)NC(=O)NN2CCCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D20 compound treatment 831124.0 298000.0 0.42 949438.0 388000.0 0.54 0.6821 0.9927 2074077 Maybridge1_008358 Fc1ccc(c2nc(C#N)cs2)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D21 compound treatment 865900.0 333000.0 0.47 939663.0 378000.0 0.53 0.7074 0.9985 2074078 Maybridge1_008359 Clc1ccc(SCc2nn[nH]n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D22 compound treatment 809488.0 276000.0 0.39 914539.0 353000.0 0.49 0.6259 0.9938 2074079 Maybridge1_008360 CCn1nc(cc1C(=O)O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D23 mock treatment 816850.0 284000.0 0.4 903052.0 341000.0 0.48 0.622 0.9966 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 D24 mock treatment 151933.0 -381000.0 -0.54 137359.0 -424000.0 -0.59 -0.8017 -0.999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E01 compound treatment 740949.0 208000.0 0.3 762836.0 201000.0 0.28 0.4074 0.9997 2074080 Maybridge1_008361 FC(F)(F)c1cccc(CSCCNC2=CC(=O)CC(C2)c3ccc(Cl)cc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E02 compound treatment 753703.0 221000.0 0.31 834931.0 273000.0 0.38 0.4913 0.9953 2074081 Maybridge1_008362 COC(=O)CSCCc1nc(cs1)c2ccc(C#N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E03 compound treatment 803667.0 270000.0 0.38 886211.0 325000.0 0.45 0.5921 0.9967 2074082 Maybridge1_008363 Cc1onc(c1C(=O)NCCSCc2ccc(Cl)cc2Cl)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E04 compound treatment 769825.0 237000.0 0.34 878535.0 317000.0 0.44 0.5505 0.9909 2074083 Maybridge1_008364 Fc1cccc(c1)c2csc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E05 compound treatment 828925.0 296000.0 0.42 924893.0 363000.0 0.51 0.6557 0.9957 1239370 Maybridge1_008365 CCOC(=O)c1cc(C)n(Cc2ccncc2)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E06 compound treatment 813293.0 280000.0 0.4 870285.0 309000.0 0.43 0.5861 0.9992 2074084 Maybridge1_008366 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E07 compound treatment 807553.0 274000.0 0.39 902554.0 341000.0 0.48 0.6122 0.9952 2074085 Maybridge1_008367 CCOC(=O)c1cc(oc1C)c2ccc(N)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E08 compound treatment 829502.0 296000.0 0.42 930679.0 369000.0 0.51 0.662 0.9951 1198978 Maybridge1_008368 COc1ccc(cc1OC)c2nc(CS(=O)(=O)c3ccsc3)no2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E09 compound treatment 850275.0 317000.0 0.45 981270.0 420000.0 0.59 0.7328 0.9917 1514731 Maybridge1_008369 OC(=O)c1csc(n1)c2ccc3OCCc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E10 compound treatment 842023.0 309000.0 0.44 889870.0 328000.0 0.46 0.6343 0.9998 1308823 Maybridge1_008370 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E11 compound treatment 859761.0 327000.0 0.46 965154.0 404000.0 0.56 0.7264 0.9954 1458517 Maybridge1_008371 Cc1c(cc(c2ccccc2)n1CCCN3CCOCC3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E12 compound treatment 823040.0 290000.0 0.41 953244.0 392000.0 0.55 0.6777 0.9904 2074086 Maybridge1_008372 Cc1oc(cc1C(=O)Nc2cc(nn2c3ccc(F)cc3)c4ccc(Cl)cc4)c5ccc(Cl)cc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E13 compound treatment 849938.0 317000.0 0.45 907747.0 346000.0 0.48 0.6599 0.9994 2074087 Maybridge1_008373 Cc1ccc(cc1)c2csc(n2)c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E14 compound treatment 859470.0 326000.0 0.46 877808.0 316000.0 0.44 0.64 0.9997 1345565 Maybridge1_008374 Cc1oc(cc1C(=O)Nc2ccccc2Cl)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E15 compound treatment 881648.0 348000.0 0.5 971662.0 410000.0 0.57 0.7548 0.9974 1401711 Maybridge1_008375 Clc1ccc(cc1)c2nc(cs2)c3ccc4OCCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E16 compound treatment 823876.0 291000.0 0.41 975469.0 414000.0 0.58 0.7005 0.9866 2074088 Maybridge1_008376 FC(F)(F)c1ccc(cc1)n2ncc(N3CCOCC3)c(Cl)c2=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E17 compound treatment 909175.0 376000.0 0.53 1077387.0 516000.0 0.72 0.8868 0.9893 2074089 Maybridge1_008377 Cc1ccc(c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E18 compound treatment 793523.0 260000.0 0.37 963536.0 402000.0 0.56 0.6582 0.9797 1249944 Maybridge1_008378 COC(=O)c1ccc(o1)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E19 compound treatment 844668.0 311000.0 0.44 954893.0 393000.0 0.55 0.7011 0.9944 2074090 Maybridge1_008379 Fc1cccc(c1)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E20 compound treatment 806338.0 273000.0 0.39 962038.0 400000.0 0.56 0.6696 0.9842 2074091 Maybridge1_008380 CCOC(=O)c1c(Cl)c(nc(Sc2ccc(C)cc2)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E21 compound treatment 852444.0 319000.0 0.45 939160.0 378000.0 0.53 0.6934 0.9973 1586173 Maybridge1_008381 COc1ccc(OCc2nc(cs2)c3ccc4OCCCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E22 compound treatment 834260.0 301000.0 0.43 907338.0 346000.0 0.48 0.6437 0.9982 2074092 Maybridge1_008382 CCN(CC)C(=O)O/N=C(\N)/c1cc(Br)c(OC)c(Br)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E23 mock treatment 804686.0 271000.0 0.39 915545.0 354000.0 0.49 0.6221 0.9926 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 E24 mock treatment 166339.0 -367000.0 -0.52 154950.0 -407000.0 -0.57 -0.7699 -0.9991 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F01 compound treatment 786324.0 253000.0 0.36 839862.0 278000.0 0.39 0.529 0.9993 2074093 Maybridge1_008383 N/C(=N\O)/COc1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F02 compound treatment 804438.0 271000.0 0.39 872549.0 311000.0 0.43 0.5794 0.9983 2074094 Maybridge1_008384 N/C(=N\O)/COc1ccc(cc1)C2SCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F03 compound treatment 816870.0 284000.0 0.4 964527.0 403000.0 0.56 0.6827 0.9868 2074095 Maybridge1_008385 O=C(CN1C(=O)CCC1=O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F04 compound treatment 809984.0 277000.0 0.39 936455.0 375000.0 0.52 0.648 0.9902 2074096 Maybridge1_008386 NC(=S)CS(=O)(=O)Cc1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F05 compound treatment 852535.0 319000.0 0.45 976644.0 415000.0 0.58 0.7305 0.9928 2074097 Maybridge1_008387 Cc1cc(C)n2nc(S)nc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F06 compound treatment 1019090.0 486000.0 0.69 1121784.0 560000.0 0.78 1.0411 0.9981 1191850 Maybridge1_008388 CC(C)S(=O)(=O)c1c(C)c(C)n(Cc2cccnc2)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F07 compound treatment 886431.0 353000.0 0.5 1020371.0 459000.0 0.64 0.8077 0.9928 2074098 Maybridge1_008389 Cc1cc(C)n2nc(Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F)nc2n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F08 compound treatment 878807.0 346000.0 0.49 1000163.0 439000.0 0.61 0.7801 0.9941 1502654 Maybridge1_008390 CCOC(=O)c1csc(COc2ccc(OC)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F09 compound treatment 901358.0 368000.0 0.52 1041930.0 480000.0 0.67 0.8439 0.9926 2074099 Maybridge1_008391 O/N=C/c1cccc(Cl)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F10 compound treatment 886773.0 354000.0 0.5 993792.0 432000.0 0.6 0.7818 0.9959 2074100 Maybridge1_008392 Cc1nc(sc1C(=O)NN)c2cccc(c2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F11 compound treatment 915866.0 383000.0 0.54 1042550.0 481000.0 0.67 0.8591 0.9946 2074101 Maybridge1_008393 NC(=S)Cc1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F12 compound treatment 885091.0 352000.0 0.5 941221.0 380000.0 0.53 0.7283 0.9996 2074102 Maybridge1_008394 Cn1c(S)nnc1Cc2ccsc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F13 compound treatment 914219.0 381000.0 0.54 978752.0 417000.0 0.58 0.7946 0.9994 1329032 Maybridge1_008395 CC(C)(C)c1cc([nH]n1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F14 compound treatment 861149.0 328000.0 0.47 984972.0 423000.0 0.59 0.7473 0.9932 2074103 Maybridge1_008396 N/C(=N\O)/COc1ccc(cc1)C2=NCCS2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F15 compound treatment 922314.0 389000.0 0.55 1056060.0 494000.0 0.69 0.879 0.994 2074104 Maybridge1_008397 N/C(=N\O)/c1ccc(Oc2ccccc2Cl)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F16 compound treatment 885123.0 352000.0 0.5 985324.0 424000.0 0.59 0.7718 0.9966 2074105 Maybridge1_008398 NC(=S)c1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F17 compound treatment 914783.0 382000.0 0.54 1066075.0 505000.0 0.7 0.8813 0.9918 2074106 Maybridge1_008399 COCCCNC(=S)NNC(=O)c1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F18 compound treatment 887229.0 354000.0 0.5 999647.0 438000.0 0.61 0.788 0.9954 2074107 Maybridge1_008400 NC(=S)CS(=O)(=O)c1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F19 compound treatment 910580.0 377000.0 0.54 1009005.0 447000.0 0.62 0.8208 0.9972 2074108 Maybridge1_008401 CCOC(=O)c1nn(C)c(C)c1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F20 compound treatment 876080.0 343000.0 0.49 1005527.0 444000.0 0.62 0.7826 0.993 2074109 Maybridge1_008402 N/C(=N\O)/c1csc(n1)c2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F21 compound treatment 919775.0 387000.0 0.55 1019735.0 458000.0 0.64 0.8406 0.9972 1198509 Maybridge1_008403 CCOC(=O)c1nc(CS(=O)(=O)c2ccc(Cl)cc2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F22 compound treatment 851626.0 318000.0 0.45 969485.0 408000.0 0.57 0.7225 0.9936 2074110 Maybridge1_008404 Fc1ccc(NC(=O)NC(=O)c2ccno2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F23 mock treatment 884482.0 351000.0 0.5 967446.0 406000.0 0.57 0.7535 0.9981 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 F24 mock treatment 148412.0 -385000.0 -0.55 154950.0 -407000.0 -0.57 -0.7879 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G01 compound treatment 767334.0 234000.0 0.33 785403.0 224000.0 0.31 0.4562 0.9995 2074111 Maybridge1_008405 FC(F)(F)c1cccc(CSCCNC2=CC(=O)CC(C2)c3ccc4OCOc4c3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G02 compound treatment 748288.0 215000.0 0.31 854952.0 293000.0 0.41 0.5056 0.9897 2074112 Maybridge1_008406 Fc1ccc(cc1F)c2csc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G03 compound treatment 788971.0 256000.0 0.36 919583.0 358000.0 0.5 0.6103 0.9879 2074113 Maybridge1_008407 Cc1nnsc1C(=O)NCCSCc2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G04 compound treatment 799786.0 267000.0 0.38 845540.0 284000.0 0.4 0.5481 0.9998 2074114 Maybridge1_008408 CCOC(=O)Cc1nn(Cc2nc(cs2)c3ccc(cc3)C(F)(F)F)c(=O)c4ccccc14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G05 compound treatment 836015.0 303000.0 0.43 889222.0 328000.0 0.46 0.6276 0.9996 2074115 Maybridge1_008409 CCOC(=O)c1cc(c2ccccc2)n(c1C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G06 compound treatment 798239.0 265000.0 0.38 890191.0 329000.0 0.46 0.5906 0.9953 2074116 Maybridge1_008410 COc1ccc(Oc2ccc(cc2c3nc(no3)c4ccccn4)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G07 compound treatment 945663.0 412000.0 0.59 1002763.0 441000.0 0.62 0.8499 0.9997 2074117 Maybridge1_008411 Cc1cc(C(=O)CC#N)c(o1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G08 compound treatment 828079.0 295000.0 0.42 922578.0 361000.0 0.5 0.6526 0.9959 1599665 Maybridge1_008412 Cc1noc(C)c1c2nc(no2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G09 compound treatment 844460.0 311000.0 0.44 963171.0 402000.0 0.56 0.7091 0.9932 2074118 Maybridge1_008413 OC(=O)c1cc(oc1C(F)(F)F)c2ccc(Br)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G10 compound treatment 846311.0 313000.0 0.45 932755.0 371000.0 0.52 0.6809 0.9972 2074119 Maybridge1_008414 Cc1ccc(cc1C)n2nc(cc2N)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G11 compound treatment 869885.0 337000.0 0.48 959983.0 398000.0 0.56 0.7315 0.9973 2074120 Maybridge1_008415 Cc1c(cc(c2ccccc2)n1CCSCCO)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G12 compound treatment 862011.0 329000.0 0.47 937137.0 376000.0 0.52 0.701 0.9984 2074121 Maybridge1_008416 Cc1oc(cc1C(=O)Nc2cc(nn2c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c4ccco4)c5ccc(Cl)cc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G13 compound treatment 888969.0 356000.0 0.51 944304.0 383000.0 0.53 0.7352 0.9996 2074122 Maybridge1_008417 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3ccc(cc3)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G14 compound treatment 868922.0 336000.0 0.48 914037.0 352000.0 0.49 0.6852 0.9999 1586499 Maybridge1_008418 Cc1oc(cc1C(=O)Nc2ccc(cc2)C(C)(C)C)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G15 compound treatment 891036.0 358000.0 0.51 975469.0 414000.0 0.58 0.768 0.998 1918664 Maybridge1_008419 Cc1nc(cs1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G16 compound treatment 888380.0 355000.0 0.51 950354.0 389000.0 0.54 0.7406 0.9994 2074123 Maybridge1_008420 COc1ccccc1N2CCN(Cc3nc(C)c(s3)C(=O)C)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G17 compound treatment 911784.0 379000.0 0.54 985034.0 423000.0 0.59 0.7983 0.9989 2074124 Maybridge1_008421 Cc1ccc(cc1)c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G18 compound treatment 870324.0 337000.0 0.48 952012.0 390000.0 0.54 0.7241 0.998 1600126 Maybridge1_008422 COC(=O)c1ccc(o1)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G19 compound treatment 924318.0 391000.0 0.56 964200.0 403000.0 0.56 0.7904 1.0 2074125 Maybridge1_008423 FC(F)(F)c1ccc(Oc2ccc(cc2)c3nc(cs3)c4ccc(C#N)cc4)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G20 compound treatment 835835.0 303000.0 0.43 894453.0 333000.0 0.46 0.6326 0.9993 2074126 Maybridge1_008424 CCOC(=O)c1c(Cl)c(nc(N2CCOCC2)c1C#N)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G21 compound treatment 877530.0 344000.0 0.49 930894.0 369000.0 0.52 0.7105 0.9997 1230345 Maybridge1_008425 COc1ccc(OCc2nc(cs2)c3ccc(C)cc3C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G22 compound treatment 858355.0 325000.0 0.46 933829.0 372000.0 0.52 0.6941 0.9983 2074127 Maybridge1_008426 Cn1c(S)nnc1c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G23 mock treatment 886024.0 353000.0 0.5 915588.0 354000.0 0.49 0.7039 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 G24 mock treatment 174197.0 -359000.0 -0.51 176974.0 -385000.0 -0.54 -0.7403 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H01 compound treatment 764061.0 231000.0 0.33 816843.0 255000.0 0.36 0.4839 0.9992 2074128 Maybridge1_008427 COCCCn1c(n[nH]c1=S)c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H02 compound treatment 952661.0 419000.0 0.6 1087997.0 526000.0 0.73 0.941 0.9947 1510220 Maybridge1_008428 Cc1c(C)n(Cc2cccs2)c(N)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H03 compound treatment 786075.0 253000.0 0.36 933540.0 372000.0 0.52 0.6211 0.984 2074129 Maybridge1_008429 OC(=O)CCC(=O)NCC(=O)c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H04 compound treatment 780868.0 248000.0 0.35 927496.0 366000.0 0.51 0.6099 0.9836 2074130 Maybridge1_008430 CCOC(=O)c1csc(COc2ccccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H05 compound treatment 830574.0 297000.0 0.42 965984.0 404000.0 0.56 0.6979 0.9899 2074131 Maybridge1_008431 Nc1n[nH]c(SCc2ccc(Cl)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H06 compound treatment 768531.0 235000.0 0.33 908705.0 347000.0 0.48 0.579 0.9837 1459095 Maybridge1_008432 NC(=S)CS(=O)(=O)Cc1ccc(F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H07 compound treatment 838709.0 306000.0 0.43 976604.0 415000.0 0.58 0.7165 0.99 2074132 Maybridge1_008433 Brc1ccc(OC(=O)c2cccs2)c(c1)C3SCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H08 compound treatment 1038511.0 505000.0 0.72 1155507.0 594000.0 0.83 1.0939 0.9975 1694073 Maybridge1_008434 CCCS(=O)(=O)c1c(C)c(C)n(Cc2ccccc2)c1N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H09 compound treatment 850178.0 317000.0 0.45 979944.0 418000.0 0.58 0.7314 0.9919 2074133 Maybridge1_008435 [O-][N+](=O)c1cc(C#N)ccc1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H10 compound treatment 824987.0 292000.0 0.41 981441.0 420000.0 0.59 0.7075 0.9858 1571326 Maybridge1_008436 Cc1nc(cs1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H11 compound treatment 878951.0 346000.0 0.49 1028928.0 467000.0 0.65 0.8086 0.9903 2074134 Maybridge1_008437 CC(C)(C)c1ccc(cc1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H12 compound treatment 850111.0 317000.0 0.45 926900.0 365000.0 0.51 0.679 0.9981 2074135 Maybridge1_008438 Cn1c(S)nnc1c2csc(n2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H13 compound treatment 877122.0 344000.0 0.49 996993.0 435000.0 0.61 0.7753 0.9942 2074136 Maybridge1_008439 CSC(=S)NNC(=O)c1cc(C)on1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H14 compound treatment 871596.0 338000.0 0.48 955120.0 394000.0 0.55 0.7284 0.9979 2074137 Maybridge1_008440 Clc1cccc(Cl)c1OCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H15 compound treatment 879287.0 346000.0 0.49 1028075.0 467000.0 0.65 0.8081 0.9905 2074138 Maybridge1_008441 NC(=S)COc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H16 compound treatment 823502.0 290000.0 0.41 959629.0 398000.0 0.56 0.6845 0.9894 2074139 Maybridge1_008442 CC(C)Nc1ccc(Cl)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H17 compound treatment 885439.0 352000.0 0.5 1041974.0 480000.0 0.67 0.828 0.9897 2074140 Maybridge1_008443 CCCCCCCCCCCc1nnc(S)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H18 compound treatment 803948.0 271000.0 0.39 967029.0 405000.0 0.57 0.6721 0.9825 2074141 Maybridge1_008444 CC(C)n1c(S)nc2cc(Cl)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H19 compound treatment 867267.0 334000.0 0.48 999356.0 438000.0 0.61 0.7677 0.9923 2074142 Maybridge1_008445 FC(F)(F)c1ccc(cc1)n2cnnc2S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H20 compound treatment 864991.0 332000.0 0.47 938047.0 376000.0 0.53 0.7049 0.9986 1544875 Maybridge1_008446 CCOC(=O)c1sc(nc1OCc2ccc(Cl)cc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H21 compound treatment 875159.0 342000.0 0.49 997333.0 436000.0 0.61 0.7736 0.9939 2074143 Maybridge1_008447 Cc1nn(C)c(C(=O)N)c1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H22 compound treatment 838936.0 306000.0 0.43 959336.0 398000.0 0.55 0.6997 0.9927 2074144 Maybridge1_008448 CC(=O)c1ccc(Oc2ncc(s2)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H23 mock treatment 842522.0 309000.0 0.44 945146.0 384000.0 0.53 0.6893 0.9953 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 H24 mock treatment 141508.0 -392000.0 -0.56 165574.0 -396000.0 -0.55 -0.7844 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I01 compound treatment 784855.0 252000.0 0.36 818089.0 257000.0 0.36 0.506 1.0 2074145 Maybridge1_008449 CN(C)c1ccc(cc1)C2CC(=O)C=C(C2)NCCSCc3c(C)cc(C)cc3C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I02 compound treatment 787934.0 255000.0 0.36 850807.0 289000.0 0.4 0.5414 0.9986 2074146 Maybridge1_008450 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2csc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I03 compound treatment 806089.0 273000.0 0.39 940670.0 379000.0 0.53 0.6483 0.9884 1236791 Maybridge1_008451 OC(=O)c1ccccc1NCc2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I04 compound treatment 807451.0 274000.0 0.39 895291.0 334000.0 0.47 0.6049 0.9961 2074147 Maybridge1_008452 Cc1c(sc2ccc(Cl)cc12)c3csc(n3)c4ccc(cc4)C5SCCS5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I05 compound treatment 859134.0 326000.0 0.46 933901.0 372000.0 0.52 0.695 0.9984 2074148 Maybridge1_008453 CCOC(=O)C(CC(=O)c1ccc(Cl)cc1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I06 compound treatment 809142.0 276000.0 0.39 910658.0 349000.0 0.49 0.6218 0.9943 1154021 Maybridge1_008454 Cc1onc(c1c2nc(no2)c3ccccn3)c4c(F)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I07 compound treatment 869877.0 337000.0 0.48 935566.0 374000.0 0.52 0.7074 0.9991 1043838 Maybridge1_008455 Cc1cc(C)c(C(=O)N)c(N)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I08 compound treatment 860650.0 327000.0 0.47 930867.0 369000.0 0.52 0.6935 0.9987 2074149 Maybridge1_008456 CCn1nc(C)c(Br)c1c2nc(CS(=O)(=O)c3ccsc3)no2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I09 compound treatment 889412.0 356000.0 0.51 1002791.0 441000.0 0.62 0.7933 0.9953 2074150 Maybridge1_008457 OC(=O)c1cc(oc1C(F)(F)F)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I10 compound treatment 853854.0 321000.0 0.46 950382.0 389000.0 0.54 0.7059 0.9963 1308808 Maybridge1_008458 Clc1ccc(cc1)c2cc(NC(=O)C3CCC3)n(n2)c4ccc(I)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I11 compound treatment 909243.0 376000.0 0.53 970889.0 409000.0 0.57 0.7818 0.9995 1394972 Maybridge1_008459 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)Nc4cc(C)cc(C)c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I12 compound treatment 834844.0 302000.0 0.43 901494.0 340000.0 0.47 0.6386 0.9988 2074151 Maybridge1_008460 Nc1cc(nn1c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I13 compound treatment 888241.0 355000.0 0.5 944941.0 383000.0 0.53 0.7351 0.9996 2074152 Maybridge1_008461 Cc1c(sc2ccccc12)c3csc(n3)c4ccc(cc4)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I14 compound treatment 883349.0 350000.0 0.5 959839.0 398000.0 0.56 0.7449 0.9985 2074153 Maybridge1_008462 Cc1oc(cc1C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I15 compound treatment 899393.0 366000.0 0.52 975903.0 414000.0 0.58 0.7769 0.9987 2071433 Maybridge1_008463 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I16 compound treatment 883447.0 350000.0 0.5 960230.0 399000.0 0.56 0.7454 0.9985 2074154 Maybridge1_008464 FC(F)(F)c1ccc(SCc2noc(COc3ccc(Cl)cc3Cl)n2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I17 compound treatment 911199.0 378000.0 0.54 1013198.0 452000.0 0.63 0.8255 0.9969 2074155 Maybridge1_008465 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I18 compound treatment 876836.0 344000.0 0.49 964296.0 403000.0 0.56 0.7427 0.9976 2074156 Maybridge1_008466 Cc1oc(C)c(c1C(=O)O)S(=O)(=O)NCc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I19 compound treatment 897913.0 365000.0 0.52 948395.0 387000.0 0.54 0.7482 0.9998 2074157 Maybridge1_008467 Cc1onc(c1c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I20 compound treatment 879737.0 347000.0 0.49 944073.0 383000.0 0.53 0.7257 0.9992 1653730 Maybridge1_008468 CC(C)N(C(C)C)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I21 compound treatment 922922.0 390000.0 0.55 956530.0 395000.0 0.55 0.7814 1.0 2074158 Maybridge1_008469 COC(=O)CSCCc1nc(cs1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I22 compound treatment 859157.0 326000.0 0.46 931208.0 370000.0 0.52 0.6923 0.9986 2074159 Maybridge1_008470 COc1ccc(cc1)c2noc(CSc3nnc(n3C)C(F)(F)F)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I23 mock treatment 875405.0 342000.0 0.49 939434.0 378000.0 0.53 0.7168 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 I24 mock treatment 151189.0 -382000.0 -0.54 151765.0 -410000.0 -0.57 -0.7883 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J01 compound treatment 762637.0 229000.0 0.33 841106.0 280000.0 0.39 0.5064 0.9961 2074160 Maybridge1_008471 CCOC(=O)c1nc(no1)c2ccc(cc2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J02 compound treatment 818879.0 286000.0 0.41 959248.0 398000.0 0.55 0.6795 0.9883 1725199 Maybridge1_008472 Cc1c(C)n(Cc2c(Cl)cccc2Cl)c(N)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J03 compound treatment 796468.0 263000.0 0.37 935176.0 374000.0 0.52 0.6332 0.9869 1061396 Maybridge1_008473 CCOC(=O)NNC(=S)Nc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J04 compound treatment 771164.0 238000.0 0.34 899854.0 338000.0 0.47 0.5729 0.9867 2074161 Maybridge1_008474 Cc1cc(Oc2ccc(cc2[N+](=O)[O-])/C(=N/O)/N)cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J05 compound treatment 804324.0 271000.0 0.39 959430.0 398000.0 0.55 0.665 0.9842 2074162 Maybridge1_008475 Nc1n[nH]c(SCc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J06 compound treatment 802705.0 270000.0 0.38 961511.0 400000.0 0.56 0.6654 0.9832 2074163 Maybridge1_008476 CCOC(=O)c1csc(COc2cc(Cl)cc(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J07 compound treatment 847387.0 314000.0 0.45 968834.0 407000.0 0.57 0.7176 0.9929 2074164 Maybridge1_008477 Cn1c(SCC#N)nnc1c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J08 compound treatment 990072.0 457000.0 0.65 1102532.0 541000.0 0.75 0.9929 0.9972 1508250 Maybridge1_008478 Cc1c(C)n(Cc2ccccc2)c(N)c1S(=O)(=O)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J09 compound treatment 859677.0 326000.0 0.46 986955.0 425000.0 0.59 0.7478 0.9926 2074165 Maybridge1_008479 CCCCCc1ccc(cc1)c2nnc(S)[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J10 compound treatment 860037.0 327000.0 0.46 964913.0 403000.0 0.56 0.7264 0.9955 2074166 Maybridge1_008480 c1csc(c1)c2nn[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J11 compound treatment 878399.0 345000.0 0.49 963497.0 402000.0 0.56 0.7435 0.9978 2074167 Maybridge1_008481 CCOC(=O)c1sc(nc1C)c2cccc(c2)n3cccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J12 compound treatment 864063.0 331000.0 0.47 927995.0 366000.0 0.51 0.6941 0.9991 2074168 Maybridge1_008482 Cn1c(Cc2ccsc2)nnc1SCC(=O)Nc3cc(Cl)cc(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J13 compound treatment 864310.0 331000.0 0.47 972747.0 411000.0 0.57 0.7385 0.9952 2074169 Maybridge1_008483 CCOC(=O)c1cc(N)n(n1)c2nc3cc(Cl)ccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J14 compound treatment 859891.0 327000.0 0.46 981789.0 420000.0 0.59 0.7429 0.9934 2074170 Maybridge1_008484 Cc1cc(OCC#N)cc(C)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J15 compound treatment 873907.0 341000.0 0.48 952097.0 391000.0 0.54 0.7278 0.9983 2074171 Maybridge1_008485 NC(=S)COc1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J16 compound treatment 867805.0 335000.0 0.48 963257.0 402000.0 0.56 0.7326 0.9967 2074172 Maybridge1_008486 CCOC(=O)c1sc(nc1O)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J17 compound treatment 865751.0 333000.0 0.47 1014145.0 453000.0 0.63 0.7807 0.9899 2074173 Maybridge1_008487 Fc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J18 compound treatment 831573.0 298000.0 0.42 1001399.0 440000.0 0.61 0.7338 0.9838 1448201 Maybridge1_008488 CCn1c(SCC(=O)O)nc2cc(Cl)ccc12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J19 compound treatment 837924.0 305000.0 0.43 1004262.0 443000.0 0.62 0.743 0.985 2074174 Maybridge1_008489 NC(=N)COc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J20 compound treatment 853138.0 320000.0 0.45 958238.0 397000.0 0.55 0.7129 0.9953 1650911 Maybridge1_008490 CCOC(=O)c1sc(nc1OCc2ccccc2Cl)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J21 compound treatment 883932.0 351000.0 0.5 968620.0 407000.0 0.57 0.7541 0.9979 1423671 Maybridge1_008491 NC(=S)CS(=O)(=O)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J22 compound treatment 786536.0 253000.0 0.36 950083.0 389000.0 0.54 0.6379 0.9803 2074175 Maybridge1_008492 CCn1nc(C)c([N+](=O)[O-])c1C(=O)Nc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J23 mock treatment 855808.0 323000.0 0.46 973887.0 412000.0 0.58 0.731 0.9937 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 J24 mock treatment 120291.0 -413000.0 -0.59 164359.0 -397000.0 -0.55 -0.8069 -0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K01 compound treatment 783656.0 250000.0 0.36 802205.0 241000.0 0.34 0.4892 0.9996 2074176 Maybridge1_008493 CS(=O)(=O)/C(=C/c1sccc1Cl)/C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K02 compound treatment 780913.0 248000.0 0.35 850994.0 289000.0 0.4 0.5345 0.9977 2074177 Maybridge1_008494 FC(F)(F)c1ccc(cc1)c2nc(cs2)c3ccc4OCCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K03 compound treatment 810507.0 277000.0 0.39 908541.0 347000.0 0.48 0.621 0.9948 2074178 Maybridge1_008495 COC(=O)c1cc(C)[nH]c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K04 compound treatment 811475.0 278000.0 0.4 850979.0 289000.0 0.4 0.5652 1.0 1396826 Maybridge1_008496 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2csc(CC#N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K05 compound treatment 852934.0 320000.0 0.45 910066.0 348000.0 0.49 0.6652 0.9994 2074179 Maybridge1_008497 OC(=O)c1cc(oc1C(F)(F)F)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K06 compound treatment 828654.0 295000.0 0.42 866046.0 304000.0 0.42 0.5974 1.0 2074180 Maybridge1_008498 Cc1nc(cs1)c2ccc3c(c2)C(C)(C)CCC3(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K07 compound treatment 835299.0 302000.0 0.43 914220.0 353000.0 0.49 0.6516 0.9977 2074181 Maybridge1_008499 CC(=O)c1cc(oc1C)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K08 compound treatment 829388.0 296000.0 0.42 905287.0 344000.0 0.48 0.6368 0.9979 1204325 Maybridge1_008500 Fc1ccc(c2nc(CS(=O)(=O)c3ccsc3)no2)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K09 compound treatment 877059.0 344000.0 0.49 939215.0 378000.0 0.53 0.7182 0.9993 1432393 Maybridge1_008501 Cc1cc(C(=O)O)c(C)n1Cc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K10 compound treatment 836154.0 303000.0 0.43 914253.0 353000.0 0.49 0.6525 0.9978 1530866 Maybridge1_008502 Fc1cccc(c1)S(=O)(=O)Nc2cc(nn2c3ccc(I)cc3)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K11 compound treatment 891110.0 358000.0 0.51 927292.0 366000.0 0.51 0.7206 1.0 2074182 Maybridge1_008503 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3ccc(F)c(F)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K12 compound treatment 854920.0 322000.0 0.46 875254.0 314000.0 0.44 0.6329 0.9997 2074183 Maybridge1_008504 Cc1n(CCSCc2c(Cl)cccc2Cl)c(c3ccccc3)c4cn[nH]c(=O)c14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K13 compound treatment 861572.0 328000.0 0.47 912241.0 351000.0 0.49 0.676 0.9997 2074184 Maybridge1_008505 Cc1c(sc2ccc(Cl)cc12)c3csc(n3)c4ccc(cc4)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K14 compound treatment 874256.0 341000.0 0.49 858188.0 297000.0 0.41 0.6355 0.9969 2074185 Maybridge1_008506 Cc1oc(cc1C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K15 compound treatment 908832.0 376000.0 0.53 937510.0 376000.0 0.52 0.7485 1.0 2074186 Maybridge1_008507 CC(C)OC(=O)Cc1csc(n1)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K16 compound treatment 866240.0 333000.0 0.47 898574.0 337000.0 0.47 0.6673 1.0 2074187 Maybridge1_008508 CN(NC(=O)c1ccc(F)cc1F)c2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K17 compound treatment 897689.0 364000.0 0.52 970216.0 409000.0 0.57 0.7695 0.9989 2074188 Maybridge1_008509 Cc1c(sc2ccccc12)c3csc(n3)c4ccc(Oc5ccc(cn5)C(F)(F)F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K18 compound treatment 857113.0 324000.0 0.46 934663.0 373000.0 0.52 0.6937 0.9982 1247083 Maybridge1_008510 Cc1oc(cc1C(=O)O)S(=O)(=O)N2CCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K19 compound treatment 904812.0 372000.0 0.53 969330.0 408000.0 0.57 0.7758 0.9993 2074189 Maybridge1_008511 FC(F)(F)c1ccc(cc1)c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K20 compound treatment 865557.0 332000.0 0.47 947976.0 386000.0 0.54 0.7153 0.9979 2074190 Maybridge1_008512 CC(C)(C)c1ccc(cc1)c2nc(S)n[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K21 compound treatment 906324.0 373000.0 0.53 978147.0 417000.0 0.58 0.786 0.999 1153384 Maybridge1_008513 COc1ccc(OCc2nc(cs2)c3ccc(C)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K22 compound treatment 836370.0 303000.0 0.43 923610.0 362000.0 0.5 0.6619 0.9969 1473078 Maybridge1_008514 CC(C)(C)c1ccc(cc1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K23 mock treatment 873631.0 340000.0 0.48 932566.0 371000.0 0.52 0.7082 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 K24 mock treatment 165249.0 -368000.0 -0.52 172248.0 -389000.0 -0.54 -0.7539 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L01 compound treatment 741747.0 209000.0 0.3 827043.0 265000.0 0.37 0.4715 0.994 2074191 Maybridge1_008515 CCOC(=O)c1nc(no1)c2cccc(C)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L02 compound treatment 727140.0 194000.0 0.28 870653.0 309000.0 0.43 0.4998 0.9767 2074192 Maybridge1_008516 N/C(=N\O)/c1ccc(Oc2ccc(F)cc2F)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L03 compound treatment 815456.0 282000.0 0.4 945100.0 384000.0 0.53 0.6621 0.99 2074193 Maybridge1_008517 Oc1nnc(SCC=C)n1c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L04 compound treatment 747321.0 214000.0 0.3 884652.0 323000.0 0.45 0.5339 0.9818 2074194 Maybridge1_008518 Cn1cnnc1Sc2ccc(cn2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L05 compound treatment 775120.0 242000.0 0.34 915684.0 354000.0 0.49 0.5925 0.9844 2074195 Maybridge1_008519 CN(C)/C=N/Nc1ccc(cc1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L06 compound treatment 759637.0 226000.0 0.32 914530.0 353000.0 0.49 0.5758 0.9788 2074196 Maybridge1_008520 OC(=O)c1csc(COc2cc(Cl)cc(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L07 compound treatment 829444.0 296000.0 0.42 957032.0 395000.0 0.55 0.6879 0.9912 2074197 Maybridge1_008521 Cn1c(SC/C(=N/O)/N)nnc1c2ccc(cc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L08 compound treatment 873386.0 340000.0 0.48 972836.0 411000.0 0.57 0.7477 0.9964 1412794 Maybridge1_008522 Cc1c(C)n(Cc2cccc(Cl)c2)c(N)c1S(=O)(=O)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L09 compound treatment 830587.0 297000.0 0.42 914487.0 353000.0 0.49 0.6471 0.9971 1120732 Maybridge1_008523 Nc1c(cnn1c2cc(Cl)cc(Cl)c2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L10 compound treatment 803961.0 271000.0 0.39 908652.0 347000.0 0.48 0.6146 0.9936 2074198 Maybridge1_008524 Cc1nc(cs1)c2nnc(S)n2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L11 compound treatment 852077.0 319000.0 0.45 920213.0 359000.0 0.5 0.6744 0.9988 2074199 Maybridge1_008525 NC(=O)c1ccc(Oc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L12 compound treatment 833224.0 300000.0 0.43 881390.0 320000.0 0.45 0.6171 0.9998 2074200 Maybridge1_008526 NC(=S)N/N=C/c1ccc(C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L13 compound treatment 817583.0 284000.0 0.4 948479.0 387000.0 0.54 0.6675 0.9899 2074201 Maybridge1_008527 CCOC(=O)c1cc(C)nn1C(=O)c2ccc(C)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L14 compound treatment 811590.0 278000.0 0.4 921178.0 360000.0 0.5 0.6346 0.9931 2074202 Maybridge1_008528 N/C(=N\O)/COc1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L15 compound treatment 865603.0 332000.0 0.47 943602.0 382000.0 0.53 0.711 0.9982 2074203 Maybridge1_008529 NC(=S)COc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L16 compound treatment 799746.0 267000.0 0.38 900761.0 339000.0 0.47 0.6026 0.994 1055257 Maybridge1_008530 CCNc1ccc(Cl)cc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L17 compound treatment 827589.0 294000.0 0.42 973071.0 412000.0 0.57 0.7019 0.988 2074204 Maybridge1_008531 CC(C)c1ccc(NC(=S)NC(=O)c2ccc(cc2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L18 compound treatment 834844.0 302000.0 0.43 927995.0 366000.0 0.51 0.6647 0.9962 2074205 Maybridge1_008532 CC(=O)c1sc(COc2ccccc2Cl)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L19 compound treatment 837763.0 305000.0 0.43 1004512.0 443000.0 0.62 0.7431 0.9849 1210214 Maybridge1_008533 Cc1nc(C)c(s1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L20 compound treatment 829060.0 296000.0 0.42 944859.0 383000.0 0.53 0.6755 0.993 2074206 Maybridge1_008534 CCn1nc(C)cc1c2nnc(S)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L21 compound treatment 872423.0 339000.0 0.48 981328.0 420000.0 0.59 0.7551 0.9954 2074207 Maybridge1_008535 Cc1nc(C)c(s1)c2nnc(S)n2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L22 compound treatment 838587.0 305000.0 0.43 971203.0 410000.0 0.57 0.7111 0.9908 2074208 Maybridge1_008536 FC(F)(F)c1cc(nc(SCc2csc(n2)c3cccs3)c1C#N)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L23 mock treatment 842338.0 309000.0 0.44 914903.0 353000.0 0.49 0.6593 0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 L24 mock treatment 199731.0 -333000.0 -0.47 156344.0 -405000.0 -0.57 -0.735 -0.9962 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M01 compound treatment 795176.0 262000.0 0.37 787832.0 226000.0 0.32 0.4866 0.9966 2074209 Maybridge1_008537 Cc1onc(c1c2nc(CSc3ccc(cn3)C(F)(F)F)no2)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M02 compound treatment 775786.0 243000.0 0.34 839957.0 278000.0 0.39 0.5185 0.9983 2074210 Maybridge1_008538 Cc1ccc(c2csc(n2)c3ccc(cc3)C(F)(F)F)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M03 compound treatment 830001.0 297000.0 0.42 922985.0 361000.0 0.5 0.6549 0.9961 2074211 Maybridge1_008539 COC(=O)c1cc(C)n(C)c1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M04 compound treatment 835415.0 302000.0 0.43 893634.0 332000.0 0.46 0.6314 0.9993 2074212 Maybridge1_008540 Cc1ccc(cc1C)c2csc(CC#N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M05 compound treatment 867635.0 334000.0 0.48 928558.0 367000.0 0.51 0.6982 0.9993 2074213 Maybridge1_008541 Cc1cc(C(=O)CC#N)c(C)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M06 compound treatment 816905.0 284000.0 0.4 872352.0 311000.0 0.43 0.5918 0.9994 1948412 Maybridge1_008542 CCCc1ccc(cc1)c2nc(no2)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M07 compound treatment 855609.0 322000.0 0.46 932170.0 371000.0 0.52 0.6897 0.9982 2074214 Maybridge1_008543 NC(=S)c1ccc2OCCc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M08 compound treatment 812794.0 280000.0 0.4 892172.0 331000.0 0.46 0.6072 0.9973 2074215 Maybridge1_008544 COc1ccc(Br)c(c1)c2nc(no2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M09 compound treatment 871180.0 338000.0 0.48 906946.0 345000.0 0.48 0.6805 1.0 1385796 Maybridge1_008545 Cc1cc(C(=O)O)c(C)n1Cc2ccncc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M10 compound treatment 842097.0 309000.0 0.44 913700.0 352000.0 0.49 0.6579 0.9985 2074216 Maybridge1_008546 Cc1oc(cc1C(=O)Nc2cc(nn2c3ccc(I)cc3)c4cccs4)c5ccc(Cl)cc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M11 compound treatment 884968.0 352000.0 0.5 905679.0 344000.0 0.48 0.6931 0.9998 2074217 Maybridge1_008547 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3ccc(Cl)c(Cl)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M12 compound treatment 839388.0 306000.0 0.44 894272.0 333000.0 0.46 0.636 0.9995 2074218 Maybridge1_008548 Cc1n(CCSCc2c(Cl)cccc2Cl)c(c3ccccc3)c4cnn(C)c(=O)c14 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M13 compound treatment 888176.0 355000.0 0.5 886919.0 325000.0 0.45 0.6778 0.9986 2074219 Maybridge1_008549 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3cccc(F)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M14 compound treatment 875088.0 342000.0 0.49 900963.0 339000.0 0.47 0.6785 0.9999 1458102 Maybridge1_008550 Cc1oc(cc1C(=O)Nc2ccccc2)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M15 compound treatment 876955.0 344000.0 0.49 933505.0 372000.0 0.52 0.7125 0.9996 2074220 Maybridge1_008551 Cc1nc(cs1)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M16 compound treatment 853560.0 320000.0 0.46 894934.0 333000.0 0.46 0.6509 0.9999 1610243 Maybridge1_008552 Cc1oc(cc1C(=O)O)S(=O)(=O)N2CCOCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M17 compound treatment 892989.0 360000.0 0.51 936283.0 375000.0 0.52 0.7313 0.9999 2074221 Maybridge1_008553 Cc1c(sc2ccc(Cl)cc12)c3csc(n3)c4ccc(Oc5ccc(cn5)C(F)(F)F)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M18 compound treatment 891357.0 358000.0 0.51 946182.0 385000.0 0.54 0.7395 0.9997 1589369 Maybridge1_008554 CSc1ccc(cc1)n2c(C)c(cc2c3ccccc3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M19 compound treatment 901005.0 368000.0 0.52 977999.0 416000.0 0.58 0.7805 0.9986 2074222 Maybridge1_008555 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2csc(n2)c3ccc(Oc4ccc(cn4)C(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M20 compound treatment 854573.0 321000.0 0.46 906035.0 344000.0 0.48 0.6629 0.9997 1539870 Maybridge1_008556 CCCOc1c(Cl)cc(cc1Cl)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M21 compound treatment 876199.0 343000.0 0.49 986110.0 425000.0 0.59 0.7636 0.9954 2074223 Maybridge1_008557 COc1ccc(OCc2nc(cs2)c3ccc(cc3)[N+](=O)[O-])cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M22 compound treatment 859570.0 326000.0 0.46 910151.0 349000.0 0.49 0.672 0.9997 2074224 Maybridge1_008558 CC(C)(C)c1ccc(cc1)c2nnc(S)n2c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M23 mock treatment 875992.0 343000.0 0.49 940533.0 379000.0 0.53 0.7184 0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 M24 mock treatment 362518.0 -171000.0 -0.24 630570.0 69000.0 0.1 -0.1036 -0.3967 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N01 compound treatment 762493.0 229000.0 0.33 822948.0 261000.0 0.36 0.4884 0.9985 2074225 Maybridge1_008559 CCOC(=O)NNC(=S)NC1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N02 compound treatment 753443.0 220000.0 0.31 880242.0 319000.0 0.44 0.5358 0.9853 2074226 Maybridge1_008560 Oc1nnc(S)n1CC=C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N03 compound treatment 792566.0 259000.0 0.37 937783.0 376000.0 0.52 0.6318 0.9851 2074227 Maybridge1_008561 CC(C)(C)c1ccc(cc1)c2nnc(S)n2Cc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N04 compound treatment 761152.0 228000.0 0.32 924238.0 363000.0 0.51 0.5869 0.9769 2074228 Maybridge1_008562 Fc1ccc(CS(=O)(=O)CC#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N05 compound treatment 799356.0 266000.0 0.38 918026.0 356000.0 0.5 0.6192 0.9909 2074229 Maybridge1_008563 CN(C)/C=N/NC(=O)c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N06 compound treatment 763494.0 230000.0 0.33 889289.0 328000.0 0.46 0.5548 0.9866 2074230 Maybridge1_008564 Oc1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n1c3ccccc3C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N07 compound treatment 829929.0 297000.0 0.42 938339.0 377000.0 0.53 0.67 0.9941 2074231 Maybridge1_008565 Cn1c(SC/C(=N/OC(=O)c2ccc(Cl)cc2)/N)nnc1c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N08 compound treatment 871125.0 338000.0 0.48 963209.0 402000.0 0.56 0.7359 0.9971 2074232 Maybridge1_008566 Cc1c(C)n(Cc2ccc(cc2)C(F)(F)F)c(N)c1S(=O)(=O)c3ccccn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N09 compound treatment 841591.0 308000.0 0.44 903010.0 341000.0 0.48 0.6468 0.9992 2074233 Maybridge1_008567 CC(C)c1ccc(cc1)n2c(S)nnc2c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N10 compound treatment 806554.0 273000.0 0.39 897629.0 336000.0 0.47 0.6063 0.9957 2074234 Maybridge1_008568 Cc1nc(cs1)c2nnc(Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F)n2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N11 compound treatment 832943.0 300000.0 0.43 971964.0 410000.0 0.57 0.7062 0.9895 2074235 Maybridge1_008569 Clc1ccc2sc(Oc3ccc(C#N)cc3)nc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N12 compound treatment 799448.0 266000.0 0.38 929658.0 368000.0 0.51 0.6307 0.9888 2074236 Maybridge1_008570 NC(=S)N/N=C/c1ccccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N13 compound treatment 845806.0 313000.0 0.44 950373.0 389000.0 0.54 0.6978 0.9951 2074237 Maybridge1_008571 Cc1cccc(c1)c2noc(NC(=O)O/N=C/c3ccccc3)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N14 compound treatment 838797.0 306000.0 0.43 954459.0 393000.0 0.55 0.6948 0.9934 2074238 Maybridge1_008572 CCOC(=O)c1sc(nc1O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N15 compound treatment 862881.0 330000.0 0.47 949616.0 388000.0 0.54 0.7142 0.9974 1287595 Maybridge1_008573 COc1ccc(OCC(=S)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N16 compound treatment 823686.0 290000.0 0.41 935729.0 374000.0 0.52 0.6611 0.9933 2074239 Maybridge1_008574 Sc1nnc(Cc2ccsc2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N17 compound treatment 874137.0 341000.0 0.48 961522.0 400000.0 0.56 0.7373 0.9976 2074240 Maybridge1_008575 CCCCCCCCCCCc1nnc(SCc2ccc(Cl)cc2)n1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N18 compound treatment 837161.0 304000.0 0.43 923213.0 362000.0 0.5 0.6623 0.997 2074241 Maybridge1_008576 CCOC(=O)c1sc(nc1C)n2cccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N19 compound treatment 872730.0 340000.0 0.48 957081.0 396000.0 0.55 0.7315 0.9978 2074242 Maybridge1_008577 [O-][N+](=O)c1cnc(Sc2nnc([nH]2)c3cccs3)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N20 compound treatment 820173.0 287000.0 0.41 936446.0 375000.0 0.52 0.6583 0.9925 2074243 Maybridge1_008578 CCn1nc(C)c(Br)c1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N21 compound treatment 860015.0 327000.0 0.46 966893.0 405000.0 0.57 0.7284 0.9953 2074244 Maybridge1_008579 CCn1nc(C)cc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N22 compound treatment 828982.0 296000.0 0.42 920353.0 359000.0 0.5 0.6513 0.9963 2074245 Maybridge1_008580 Clc1ccc(cc1)c2nnc(Cc3cc(Br)sc3Br)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N23 mock treatment 835386.0 302000.0 0.43 957688.0 396000.0 0.55 0.6945 0.9923 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 N24 mock treatment 333664.0 -200000.0 -0.28 380843.0 -181000.0 -0.25 -0.3789 -0.9983 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O01 compound treatment 788282.0 255000.0 0.36 797271.0 236000.0 0.33 0.489 0.9988 1165825 Maybridge1_008581 Cc1ccc(CN2CC(CC2=O)C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O02 compound treatment 746737.0 214000.0 0.3 824888.0 263000.0 0.37 0.4744 0.9955 2074246 Maybridge1_008582 [O-][N+](=O)c1ccc(cc1)c2csc(n2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O03 compound treatment 796054.0 263000.0 0.37 885756.0 324000.0 0.45 0.584 0.9955 2074247 Maybridge1_008583 COC(=O)c1c(C)[nH]c(C)c1C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O04 compound treatment 765728.0 233000.0 0.33 857281.0 296000.0 0.41 0.5255 0.994 1864077 Maybridge1_008584 [O-][N+](=O)c1ccc(cc1)c2csc(CC#N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O05 compound treatment 813676.0 280000.0 0.4 888110.0 327000.0 0.46 0.6041 0.9978 2074248 Maybridge1_008585 Cc1oc(cc1C(=O)O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O06 compound treatment 783911.0 251000.0 0.36 822422.0 261000.0 0.36 0.5094 0.9999 1293522 Maybridge1_008586 COc1ccc(cc1OC)c2nc(no2)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O07 compound treatment 827788.0 295000.0 0.42 905440.0 344000.0 0.48 0.6354 0.9977 2074249 Maybridge1_008587 Cc1oc(cc1COC(=O)Nc2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O08 compound treatment 807775.0 275000.0 0.39 848221.0 287000.0 0.4 0.5588 0.9999 2074250 Maybridge1_008588 CCn1nc(C)c(Br)c1c2nc(no2)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O09 compound treatment 838666.0 305000.0 0.43 858591.0 297000.0 0.41 0.6001 0.9997 1169901 Maybridge1_008589 Cc1c(cc(c2ccccc2)n1c3ccccc3)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O10 compound treatment 1009870.0 477000.0 0.68 983958.0 422000.0 0.59 0.8959 0.9976 2074251 Maybridge1_008590 FC(F)(F)c1cc(cc(c1)C(F)(F)F)n2nc(cc2NC(=O)C3CCC3)c4ccco4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O11 compound treatment 871250.0 338000.0 0.48 892766.0 331000.0 0.46 0.6666 0.9998 2074252 Maybridge1_008591 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O12 compound treatment 807404.0 274000.0 0.39 806978.0 245000.0 0.34 0.5178 0.9979 2074253 Maybridge1_008592 Cc1oc(cc1C(=O)N2CCN(CC2)c3ncccc3C(F)(F)F)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O13 compound treatment 881857.0 349000.0 0.5 854021.0 292000.0 0.41 0.639 0.9953 2074254 Maybridge1_008593 COC(=O)CSCCc1nc(cs1)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O14 compound treatment 827703.0 295000.0 0.42 889886.0 328000.0 0.46 0.6199 0.999 2074255 Maybridge1_008594 Cc1oc(cc1C(=O)Nc2ccc(cc2)[N+](=O)[O-])C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O15 compound treatment 866730.0 334000.0 0.47 900845.0 339000.0 0.47 0.67 1.0 2074256 Maybridge1_008595 FC(F)(F)c1ccc(Oc2ccc(cc2)c3nc(cs3)c4ccc(Cl)c(Cl)c4)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O16 compound treatment 808356.0 275000.0 0.39 863382.0 302000.0 0.42 0.5743 0.9993 1232555 Maybridge1_008596 Cc1oc(cc1C(=O)O)S(=O)(=O)N2CCCCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O17 compound treatment 862950.0 330000.0 0.47 897421.0 336000.0 0.47 0.6628 1.0 1122089 Maybridge1_008597 CC(C)(C)c1ccc(cc1)c2nc(cs2)c3ccc(C#N)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O18 compound treatment 925558.0 392000.0 0.56 963700.0 402000.0 0.56 0.7911 1.0 2074257 Maybridge1_008598 Nc1sccc1c2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O19 compound treatment 877162.0 344000.0 0.49 901198.0 340000.0 0.47 0.6808 0.9999 1195213 Maybridge1_008599 COc1ccc(OCc2nc(cs2)c3ccc(Cl)c(Cl)c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O20 compound treatment 855959.0 323000.0 0.46 876263.0 315000.0 0.44 0.6349 0.9997 2074258 Maybridge1_008600 COc1c(Br)cc(C#N)cc1Br 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O21 compound treatment 868578.0 335000.0 0.48 906716.0 345000.0 0.48 0.6776 1.0 1708870 Maybridge1_008601 COc1ccc(OCc2nc(cs2)c3sc4ccccc4c3C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O22 compound treatment 811727.0 279000.0 0.4 868930.0 307000.0 0.43 0.5832 0.9992 2074259 Maybridge1_008602 Sc1nnc([nH]1)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O23 mock treatment 859287.0 326000.0 0.46 889566.0 328000.0 0.46 0.6514 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 O24 mock treatment 564545.0 31400.0 0.04 238895.0 -323000.0 -0.45 -0.2867 -0.6339 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P01 compound treatment 744577.0 211000.0 0.3 788533.0 227000.0 0.32 0.4364 0.9997 2074260 Maybridge1_008603 COCc1cc(O)nc(Cc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P02 compound treatment 749176.0 216000.0 0.31 831810.0 270000.0 0.38 0.4837 0.9948 2074261 Maybridge1_008604 CCCCCn1c(O)nnc1S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P03 compound treatment 767847.0 235000.0 0.33 821708.0 260000.0 0.36 0.4925 0.9991 2074262 Maybridge1_008605 CC(C)(C)c1ccc(cc1)n2c(S)nnc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P04 compound treatment 765363.0 232000.0 0.33 846281.0 285000.0 0.4 0.5142 0.9958 2074263 Maybridge1_008606 CCOC(=O)c1csc(n1)c2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P05 compound treatment 779306.0 246000.0 0.35 832176.0 271000.0 0.38 0.5144 0.9993 2074264 Maybridge1_008607 CN(C)/C=N/NS(=O)(=O)c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P06 compound treatment 778576.0 245000.0 0.35 853507.0 292000.0 0.41 0.5347 0.997 2074265 Maybridge1_008608 CCCCCn1c(O)nnc1SCC(=O)Nc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P07 compound treatment 781988.0 249000.0 0.35 831709.0 270000.0 0.38 0.5166 0.9995 2074266 Maybridge1_008609 Cn1c(SC/C(=N/OC(=O)c2cccs2)/N)nnc1c3ccc(cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P08 compound treatment 773698.0 241000.0 0.34 828037.0 266000.0 0.37 0.5046 0.9991 2074267 Maybridge1_008610 CCOC(=O)c1csc(n1)c2ccc(F)cc2F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P09 compound treatment 764279.0 231000.0 0.33 841274.0 280000.0 0.39 0.5082 0.9964 2074268 Maybridge1_008611 [O-][N+](=O)c1cc(C#N)ccc1Oc2cc(Cl)cc(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P10 compound treatment 785607.0 252000.0 0.36 829723.0 268000.0 0.37 0.5183 0.9998 2074269 Maybridge1_008612 NNC(=O)Cc1csc(n1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P11 compound treatment 772690.0 239000.0 0.34 835892.0 274000.0 0.38 0.5114 0.9983 2074270 Maybridge1_008613 NC(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P12 compound treatment 789790.0 257000.0 0.36 838252.0 277000.0 0.39 0.5309 0.9996 2074271 Maybridge1_008614 NC(=S)N/N=C/c1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P13 compound treatment 799012.0 266000.0 0.38 846215.0 285000.0 0.4 0.548 0.9997 2074272 Maybridge1_008615 Cc1cc(no1)C(=O)N/N=C/C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P14 compound treatment 869032.0 336000.0 0.48 921302.0 360000.0 0.5 0.6925 0.9997 2074273 Maybridge1_008616 CCOC(=O)c1sc(nc1O)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P15 compound treatment 801659.0 268000.0 0.38 839746.0 278000.0 0.39 0.5443 1.0 2074274 Maybridge1_008617 Clc1ccc(cc1)C(=O)Oc2ccc(cc2)C3=NCCS3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P16 compound treatment 802285.0 269000.0 0.38 864210.0 303000.0 0.42 0.5691 0.9988 2074275 Maybridge1_008618 CCn1nc(C)cc1c2nnc(S)n2c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P17 compound treatment 813169.0 280000.0 0.4 874232.0 313000.0 0.44 0.5899 0.999 2074276 Maybridge1_008619 Fc1ccc(NC(=O)NC(=O)c2ccc(cc2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P18 compound treatment 813218.0 280000.0 0.4 874295.0 313000.0 0.44 0.59 0.999 1280867 Maybridge1_008620 O=c1oc2ccccc2n1CCC#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P19 compound treatment 805215.0 272000.0 0.39 867252.0 306000.0 0.43 0.575 0.9988 2074277 Maybridge1_008621 Cn1c(O)nnc1Sc2ncc(s2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P20 compound treatment 814130.0 281000.0 0.4 854520.0 293000.0 0.41 0.5714 0.9999 2074278 Maybridge1_008622 Cc1cc(no1)C(=O)NNC(=O)c2c(C)onc2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P21 compound treatment 811986.0 279000.0 0.4 851129.0 290000.0 0.4 0.5659 1.0 2074279 Maybridge1_008623 CCOC(=O)c1sc(nc1O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P22 compound treatment 804558.0 271000.0 0.39 846310.0 285000.0 0.4 0.5537 0.9999 2074280 Maybridge1_008624 FC(F)(F)c1ccc(Oc2ccc(C#N)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P23 mock treatment 793034.0 260000.0 0.37 831402.0 270000.0 0.38 0.5274 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.565 P24 mock treatment 566922.0 33700.0 0.05 360140.0 -201000.0 -0.28 -0.1647 -0.578 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A01 compound treatment 748717.0 202000.0 0.29 827413.0 259000.0 0.36 0.4587 0.9935 2074281 Maybridge1_008625 Cc1nc(no1)c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A02 compound treatment 738886.0 192000.0 0.27 806264.0 238000.0 0.33 0.428 0.9953 2074282 Maybridge1_008626 O/N=C/c1cccc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A03 compound treatment 743174.0 196000.0 0.28 799297.0 231000.0 0.32 0.4254 0.9974 2074283 Maybridge1_008627 Cc1cc(C(=O)O)n(n1)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A04 compound treatment 757272.0 211000.0 0.3 824093.0 256000.0 0.36 0.4641 0.9962 2074284 Maybridge1_008628 COC(C)(OC)c1ccc(C#N)c(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A05 compound treatment 765327.0 219000.0 0.31 824346.0 256000.0 0.36 0.4724 0.9976 2074285 Maybridge1_008629 COC(=O)c1c(C)n[nH]c1c2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A06 compound treatment 791423.0 245000.0 0.35 868234.0 300000.0 0.42 0.5419 0.9958 2074286 Maybridge1_008630 CC(C)(C)c1ccc(OCC(=N)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A07 compound treatment 801226.0 254000.0 0.36 875095.0 307000.0 0.43 0.5586 0.9965 2074287 Maybridge1_008631 CC(=O)c1csc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A08 compound treatment 816484.0 270000.0 0.38 874913.0 307000.0 0.43 0.5737 0.9985 2074288 Maybridge1_008632 NC(=O)COc1cccc(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A09 compound treatment 813231.0 266000.0 0.38 849790.0 282000.0 0.39 0.5457 0.9998 2074289 Maybridge1_008633 CC(=O)c1csc(n1)c2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A10 compound treatment 802566.0 256000.0 0.36 840674.0 273000.0 0.38 0.526 0.9998 2074290 Maybridge1_008634 Cc1ccc(Nc2nc(cs2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A11 compound treatment 810460.0 264000.0 0.37 885610.0 317000.0 0.44 0.5782 0.9966 2074291 Maybridge1_008635 FC(F)(F)Oc1ccc(cc1)c2nnc(S)n2c3ccccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A12 compound treatment 815091.0 268000.0 0.38 873813.0 306000.0 0.43 0.5712 0.9985 1044931 Maybridge1_008636 COc1ncccc1[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A13 compound treatment 829246.0 282000.0 0.4 893534.0 325000.0 0.45 0.6049 0.9982 2074292 Maybridge1_008637 Cc1nc(nc(O)c1Oc2ccc(Cl)cc2Cl)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A14 compound treatment 835257.0 288000.0 0.41 881929.0 314000.0 0.44 0.5995 0.9995 1194534 Maybridge1_008638 Cc1nn(CCC#N)c(C)c1Oc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A15 compound treatment 840996.0 294000.0 0.42 875397.0 307000.0 0.43 0.5989 0.9999 2074293 Maybridge1_008639 COC(OC)c1ccnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A16 compound treatment 827257.0 280000.0 0.4 892347.0 324000.0 0.45 0.6018 0.998 2074294 Maybridge1_008640 FC(F)(F)c1ccc(=O)n(CCC#N)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A17 compound treatment 822836.0 276000.0 0.39 895000.0 327000.0 0.46 0.5999 0.9972 1461755 Maybridge1_008641 CC(=O)Nc1nc(C)c(Oc2ccc(C)cc2)c(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A18 compound treatment 786043.0 239000.0 0.34 851979.0 284000.0 0.4 0.5205 0.9972 1022739 Maybridge1_008642 NC(=S)Nc1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A19 compound treatment 783033.0 236000.0 0.34 848580.0 280000.0 0.39 0.5141 0.9971 2074295 Maybridge1_008643 CC(=O)c1cc(no1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A20 compound treatment 776466.0 230000.0 0.33 835697.0 268000.0 0.37 0.4948 0.9978 2074296 Maybridge1_008644 OC(=O)c1cc(Cl)cnc1O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A21 compound treatment 781759.0 235000.0 0.33 797086.0 229000.0 0.32 0.4621 0.9997 2074297 Maybridge1_008645 Clc1ccc(c2cc(on2)c3csc(N/N=C/c4ccccc4)n3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A22 compound treatment 735027.0 188000.0 0.27 794691.0 227000.0 0.32 0.4127 0.9966 2074298 Maybridge1_008646 SC1=NNC(S1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A23 mock treatment 755524.0 209000.0 0.3 790918.0 223000.0 0.31 0.4296 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 A24 mock treatment 146034.0 -401000.0 -0.57 129260.0 -439000.0 -0.61 -0.8358 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B01 compound treatment 766487.0 220000.0 0.31 821862.0 254000.0 0.35 0.4711 0.9981 2074299 Maybridge1_008647 Cc1ccc(CN2C(=O)CNC2=S)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B02 compound treatment 771892.0 225000.0 0.32 800755.0 233000.0 0.32 0.4557 1.0 2074300 Maybridge1_008648 Cc1cccc(Cn2nc(cc2c3nnc(S)o3)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B03 compound treatment 824135.0 277000.0 0.39 846847.0 279000.0 0.39 0.5537 1.0 2074301 Maybridge1_008649 NNC(=S)Nc1ccc(cc1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B04 compound treatment 796882.0 250000.0 0.36 840052.0 272000.0 0.38 0.5196 0.9995 2074302 Maybridge1_008650 COc1ccc(OCCNC(=O)c2ccc(OC(F)(F)F)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B05 compound treatment 829909.0 283000.0 0.4 869275.0 301000.0 0.42 0.5817 0.9998 1735075 Maybridge1_008651 Cc1nnc(S)n1c2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B06 compound treatment 824029.0 277000.0 0.39 869767.0 302000.0 0.42 0.5762 0.9995 2074303 Maybridge1_008652 N#Cc1ccc(/C=N/Nc2nc(cs2)c3ccc4OCCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B07 compound treatment 887180.0 340000.0 0.48 894537.0 326000.0 0.46 0.6642 0.9995 2074304 Maybridge1_008653 CCOC(=O)N/N=C(/CN1C(=O)c2ccccc2C1=O)\c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B08 compound treatment 885513.0 339000.0 0.48 873727.0 306000.0 0.43 0.642 0.9981 1466613 Maybridge1_008654 O=S(=O)(Cc1ccco1)Cc2nc(cs2)c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B09 compound treatment 915588.0 369000.0 0.52 891391.0 323000.0 0.45 0.6896 0.9972 2074305 Maybridge1_008655 CCCn1c(S)nnc1Cc2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B10 compound treatment 880940.0 334000.0 0.48 863336.0 295000.0 0.41 0.6271 0.9974 2074306 Maybridge1_008656 Cc1onc(c1c2csc(n2)c3cccc(c3)C(F)(F)F)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B11 compound treatment 915007.0 368000.0 0.52 911320.0 343000.0 0.48 0.7087 0.999 2074307 Maybridge1_008657 CC(=O)N[C@@H](Cc1ccc(OC(F)(F)F)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B12 compound treatment 893997.0 347000.0 0.49 882832.0 315000.0 0.44 0.6595 0.9983 2074308 Maybridge1_008658 OC(=O)C(Cc1ccc(cc1)[N+](=O)[O-])NS(=O)(=O)c2ccc(OC(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B13 compound treatment 915209.0 368000.0 0.52 879447.0 311000.0 0.43 0.6775 0.9956 2074309 Maybridge1_008659 O=C(CSc1nncn1c2ccc(OCc3ccccc3)cc2)Nc4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B14 compound treatment 894844.0 348000.0 0.49 865991.0 298000.0 0.42 0.6437 0.9962 1112632 Maybridge1_008660 COc1ccccc1NC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B15 compound treatment 918865.0 372000.0 0.53 924947.0 357000.0 0.5 0.726 0.9995 2074310 Maybridge1_008661 Fc1cccc(c1)C(=O)CSc2nnc(c3ccco3)n2c4ccc5OCCOc5c4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B16 compound treatment 876008.0 329000.0 0.47 939856.0 372000.0 0.52 0.6976 0.9987 1682013 Maybridge1_008662 Clc1cccc(C(=O)Nc2cccnc2)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B17 compound treatment 928309.0 382000.0 0.54 930257.0 362000.0 0.51 0.7408 0.9994 2074311 Maybridge1_008663 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B18 compound treatment 856345.0 310000.0 0.44 825629.0 257000.0 0.36 0.5652 0.9949 2074312 Maybridge1_008664 COc1ccc(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B19 compound treatment 882461.0 336000.0 0.48 895083.0 327000.0 0.46 0.66 0.9997 2074313 Maybridge1_008665 CCOC(=O)c1cc(nn1Cc2c(C)cc(C)cc2C)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B20 compound treatment 817216.0 270000.0 0.38 841179.0 273000.0 0.38 0.5412 1.0 1143232 Maybridge1_008666 Cc1cc(nn1C(C)(C)C)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B21 compound treatment 852843.0 306000.0 0.44 859585.0 291000.0 0.41 0.5952 0.9994 2074314 Maybridge1_008667 N/C(=N\OC(=O)Nc1cccc2ccccc12)/Cc3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B22 compound treatment 817763.0 271000.0 0.39 847707.0 280000.0 0.39 0.5482 1.0 1640080 Maybridge1_008668 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B23 mock treatment 842294.0 296000.0 0.42 875365.0 307000.0 0.43 0.6001 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 B24 mock treatment 128798.0 -418000.0 -0.59 149879.0 -418000.0 -0.58 -0.8328 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C01 compound treatment 706471.0 160000.0 0.23 717053.0 149000.0 0.21 0.3074 0.999 2074315 Maybridge1_008669 CCOC(=O)c1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C02 compound treatment 702509.0 156000.0 0.22 776854.0 209000.0 0.29 0.3624 0.9909 2074316 Maybridge1_008670 Nc1nccc(n1)c2cc(no2)c3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C03 compound treatment 744831.0 198000.0 0.28 811837.0 244000.0 0.34 0.4395 0.9956 2074317 Maybridge1_008671 Cn1nc(cc1C(=O)O)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C04 compound treatment 720037.0 173000.0 0.25 768855.0 201000.0 0.28 0.3721 0.998 2074318 Maybridge1_008672 CC(=O)c1ccc(C#N)c(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C05 compound treatment 765230.0 218000.0 0.31 839395.0 271000.0 0.38 0.4872 0.9952 1913710 Maybridge1_008673 NC(=S)N/N=C/c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C06 compound treatment 760044.0 213000.0 0.3 819359.0 251000.0 0.35 0.4622 0.9974 1103895 Maybridge1_008674 NC(=N)COc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C07 compound treatment 802611.0 256000.0 0.36 820738.0 253000.0 0.35 0.5063 0.9999 2074319 Maybridge1_008675 FC(F)(F)Oc1ccccc1C(=O)NNC(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C08 compound treatment 804283.0 258000.0 0.37 849826.0 282000.0 0.39 0.5367 0.9994 1561598 Maybridge1_008676 COc1ccc(cn1)C(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C09 compound treatment 837270.0 290000.0 0.41 868406.0 300000.0 0.42 0.5882 1.0 1335819 Maybridge1_008677 Cc1nc(cs1)c2nc(C)nc(N)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C10 compound treatment 832241.0 285000.0 0.41 804256.0 236000.0 0.33 0.5199 0.9946 2074320 Maybridge1_008678 Cc1ccc(cn1)C(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C11 compound treatment 837407.0 291000.0 0.41 880522.0 312000.0 0.44 0.6003 0.9997 2074321 Maybridge1_008679 FC(F)(F)c1cnc(S)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C12 compound treatment 843206.0 296000.0 0.42 861756.0 294000.0 0.41 0.5876 0.9999 2074322 Maybridge1_008680 FC(F)(F)c1cccn(CCC#N)c1=O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C13 compound treatment 831580.0 285000.0 0.41 854284.0 286000.0 0.4 0.5686 1.0 2074323 Maybridge1_008681 CN(C)/C=C(/Sc1nnc(n1C)C(F)(F)F)\C(=O)c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C14 compound treatment 806284.0 260000.0 0.37 3499436.0 2930000.0 4.09 3.1518 0.7678 1953832 Maybridge1_008682 NC(=N)c1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C15 compound treatment 880642.0 334000.0 0.47 866490.0 298000.0 0.42 0.6299 0.9978 2074324 Maybridge1_008683 COC(OC)c1ccc(C#N)c(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C16 compound treatment 822668.0 276000.0 0.39 834924.0 267000.0 0.37 0.5405 0.9996 1049916 Maybridge1_008684 CC(=O)Nc1ccccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C17 compound treatment 832089.0 285000.0 0.41 887669.0 319000.0 0.45 0.602 0.9989 1288517 Maybridge1_008685 CC(=O)Nc1nc(C)c(Oc2ccccc2)c(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C18 compound treatment 774784.0 228000.0 0.32 835734.0 268000.0 0.37 0.4932 0.9975 1008101 Maybridge1_008686 Cc1ccccc1NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C19 compound treatment 812526.0 266000.0 0.38 864318.0 296000.0 0.41 0.5593 0.999 2074325 Maybridge1_008687 C/C(=N\NS(=O)(=O)c1ccc(Cl)cc1)/c2cc(no2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C20 compound treatment 769793.0 223000.0 0.32 793483.0 225000.0 0.31 0.4465 1.0 1499311 Maybridge1_008688 Clc1cncc(Cl)c1N2CCN(CC2)C(=O)Nc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C21 compound treatment 807472.0 261000.0 0.37 856224.0 288000.0 0.4 0.5462 0.9992 2074326 Maybridge1_008689 CC(=O)c1c(C)onc1c2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C22 compound treatment 757807.0 211000.0 0.3 806177.0 238000.0 0.33 0.4469 0.9987 2074327 Maybridge1_008690 Cn1cc(Cl)c(n1)C2NN=C(S)S2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C23 mock treatment 768335.0 222000.0 0.32 807025.0 239000.0 0.33 0.4584 0.9996 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 C24 mock treatment 165103.0 -382000.0 -0.54 140827.0 -427000.0 -0.6 -0.8052 -0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D01 compound treatment 745981.0 199000.0 0.28 794045.0 226000.0 0.32 0.4231 0.9986 2074328 Maybridge1_008691 NNC(=O)c1ccc(F)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D02 compound treatment 748438.0 202000.0 0.29 802191.0 234000.0 0.33 0.4336 0.9979 2074329 Maybridge1_008692 Cn1c(S)nnc1c2cc(nn2Cc3ccc(Cl)cc3Cl)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D03 compound treatment 770777.0 224000.0 0.32 873141.0 305000.0 0.43 0.526 0.9899 2074330 Maybridge1_008693 FC(F)(F)c1ccccc1n2cnnc2S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D04 compound treatment 787627.0 241000.0 0.34 826477.0 258000.0 0.36 0.4969 0.9997 2074331 Maybridge1_008694 COc1ccc(OCCNC(=O)c2c(C)noc2c3c(F)cccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D05 compound treatment 800940.0 254000.0 0.36 897472.0 329000.0 0.46 0.5803 0.993 2074332 Maybridge1_008695 Sc1nnc(c2ccco2)n1c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D06 compound treatment 801852.0 255000.0 0.36 866450.0 298000.0 0.42 0.5507 0.9977 1495996 Maybridge1_008696 O=S(=O)(Cc1nc(cs1)c2ccc3OCCOc3c2)c4ccccn4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D07 compound treatment 854490.0 308000.0 0.44 851581.0 283000.0 0.4 0.5889 0.9987 1628175 Maybridge1_008697 O=C1N(C(=O)c2ccccc12)c3snnc3c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D08 compound treatment 870371.0 324000.0 0.46 882179.0 314000.0 0.44 0.6351 0.9997 1217127 Maybridge1_008698 Clc1ccc(OCc2nc(cs2)c3ccc4OCCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D09 compound treatment 889853.0 343000.0 0.49 929095.0 361000.0 0.5 0.7009 0.9999 2074333 Maybridge1_008699 Sc1nnc(Cc2ccc(Cl)c(Cl)c2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D10 compound treatment 872921.0 326000.0 0.46 875246.0 307000.0 0.43 0.6308 0.9992 1380282 Maybridge1_008700 COc1ccccc1OCc2nc(cs2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D11 compound treatment 887564.0 341000.0 0.48 920397.0 352000.0 0.49 0.6901 1.0 1589372 Maybridge1_008701 CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D12 compound treatment 875564.0 329000.0 0.47 884264.0 316000.0 0.44 0.6424 0.9996 1638560 Maybridge1_008702 Cc1onc(c1C(=O)N2CCN(CC2)c3ccc(C#N)cc3)c4c(Cl)cccc4Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D13 compound treatment 903594.0 357000.0 0.51 888772.0 321000.0 0.45 0.675 0.998 2074334 Maybridge1_008703 Clc1cc(Cl)cc(NC(=O)CSc2nncn2c3ccc(OCc4ccccc4)cc3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D14 compound treatment 881205.0 334000.0 0.48 886089.0 318000.0 0.44 0.6498 0.9994 1929843 Maybridge1_008704 Clc1cccc(c1)C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D15 compound treatment 937492.0 391000.0 0.56 951600.0 383000.0 0.53 0.771 0.9998 2074335 Maybridge1_008705 O=C(CSc1nnc(c2ccco2)n1c3ccc4OCCOc4c3)c5ccccc5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D16 compound treatment 875611.0 329000.0 0.47 892147.0 324000.0 0.45 0.6502 0.9999 2074336 Maybridge1_008706 Fc1cccc(F)c1C(=O)Nc2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D17 compound treatment 906631.0 360000.0 0.51 962174.0 394000.0 0.55 0.7504 0.9994 2074337 Maybridge1_008707 Cc1onc(c1C(=O)N2C[C@H]3CCCC[C@H]3C[C@H]2C(=O)NC(C)(C)C)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D18 compound treatment 806931.0 260000.0 0.37 888756.0 321000.0 0.45 0.5778 0.9956 2074338 Maybridge1_008708 COc1ccc(NC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cn1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D19 compound treatment 867181.0 320000.0 0.46 942958.0 375000.0 0.52 0.6918 0.9977 1317425 Maybridge1_008709 Cc1cccc(Cn2nc(cc2C(=O)O)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D20 compound treatment 842735.0 296000.0 0.42 866738.0 299000.0 0.42 0.5921 1.0 1638488 Maybridge1_008710 CC(C)(C)NC(=S)NC1CCN(Cc2ccccc2)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D21 compound treatment 863754.0 317000.0 0.45 906053.0 338000.0 0.47 0.652 0.9998 2074339 Maybridge1_008711 N/C(=N\OC(=O)Nc1cc(Cl)cc(Cl)c1)/Cc2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D22 compound treatment 804263.0 257000.0 0.37 861887.0 294000.0 0.41 0.5486 0.9984 1409426 Maybridge1_008712 CN1CCN(CC1)c2ccc(NC(=O)c3ccc(F)cc3F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D23 mock treatment 818532.0 272000.0 0.39 872409.0 304000.0 0.42 0.5733 0.9989 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 D24 mock treatment 124157.0 -423000.0 -0.6 171243.0 -397000.0 -0.55 -0.8164 -0.9992 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E01 compound treatment 733508.0 187000.0 0.27 813813.0 246000.0 0.34 0.43 0.9921 2074340 Maybridge1_008713 NC(=S)c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E02 compound treatment 751268.0 204000.0 0.29 816511.0 248000.0 0.35 0.4505 0.9962 2074341 Maybridge1_008714 CC(=O)c1cc(no1)c2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E03 compound treatment 802051.0 255000.0 0.36 842243.0 274000.0 0.38 0.527 0.9997 2074342 Maybridge1_008715 FC(F)(F)c1ccc(nc1)n2cncn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E04 compound treatment 784612.0 238000.0 0.34 831172.0 263000.0 0.37 0.4985 0.9992 2074343 Maybridge1_008716 Cc1nnsc1c2c(C(=O)O)c(C)nn2c3ccc(OC(F)(F)F)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E05 compound treatment 833994.0 287000.0 0.41 883763.0 316000.0 0.44 0.6001 0.9993 2074344 Maybridge1_008717 NC(=S)N/N=C/c1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E06 compound treatment 812902.0 266000.0 0.38 847157.0 279000.0 0.39 0.5427 0.9999 2074345 Maybridge1_008718 Cc1c(sc2nc(nn12)C(F)(F)F)c3ccn[nH]3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E07 compound treatment 846310.0 300000.0 0.43 871596.0 303000.0 0.42 0.6004 1.0 2074346 Maybridge1_008719 FC(F)(F)Oc1ccccc1c2nnc(o2)c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E08 compound treatment 862834.0 316000.0 0.45 877465.0 309000.0 0.43 0.6228 0.9998 2074347 Maybridge1_008720 FC(F)(F)c1ccncc1c2nc(cs2)c3ccc(C#N)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E09 compound treatment 899092.0 352000.0 0.5 912224.0 344000.0 0.48 0.6936 0.9998 2074348 Maybridge1_008721 CC(=O)c1csc(n1)c2csc(C)n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E10 compound treatment 853160.0 306000.0 0.44 903585.0 335000.0 0.47 0.6389 0.9994 1208553 Maybridge1_008722 NC(=S)c1ccc(Oc2ccc(Cl)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E11 compound treatment 915858.0 369000.0 0.52 893560.0 325000.0 0.45 0.692 0.9974 2074349 Maybridge1_008723 N/C(=N\O)/CSc1ncccc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E12 compound treatment 879776.0 333000.0 0.47 896180.0 328000.0 0.46 0.6583 0.9999 2074350 Maybridge1_008724 NC(=N)CSc1ccc(Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E13 compound treatment 902470.0 356000.0 0.51 899872.0 332000.0 0.46 0.6848 0.999 2074351 Maybridge1_008725 Cc1n[nH]cc1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E14 compound treatment 862434.0 316000.0 0.45 896221.0 328000.0 0.46 0.6409 1.0 1037237 Maybridge1_008726 CCOC(=O)C(Nc1ccc(Cl)cc1)C(=O)OCC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E15 compound treatment 911174.0 364000.0 0.52 918724.0 351000.0 0.49 0.7121 0.9996 1002860 Maybridge1_008727 NC(=O)COc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E16 compound treatment 870512.0 324000.0 0.46 908106.0 340000.0 0.47 0.6608 0.9999 1033719 Maybridge1_008728 CC(=O)Nc1ccccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E17 compound treatment 1079435.0 533000.0 0.76 1073530.0 505000.0 0.7 1.034 0.9994 2074352 Maybridge1_008729 Cc1nc(N)ncc1Sc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E18 compound treatment 853378.0 307000.0 0.44 898080.0 330000.0 0.46 0.6337 0.9996 2074353 Maybridge1_008730 Cc1onc(c1C(=O)NC(=N)c2ccccc2)c3c(Cl)cccc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E19 compound treatment 852648.0 306000.0 0.43 868601.0 300000.0 0.42 0.6039 0.9998 2074354 Maybridge1_008731 O/N=C/c1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E20 compound treatment 844438.0 298000.0 0.42 913001.0 345000.0 0.48 0.6394 0.998 1047541 Maybridge1_008732 NNC(=S)NC1CCCCC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E21 compound treatment 849804.0 303000.0 0.43 918062.0 350000.0 0.49 0.6498 0.9981 1091162 Maybridge1_008733 CC(=O)c1c(C)onc1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E22 compound treatment 807552.0 261000.0 0.37 875239.0 307000.0 0.43 0.5651 0.9974 2074355 Maybridge1_008734 NNC(=S)NCc1ccco1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E23 mock treatment 852745.0 306000.0 0.44 860351.0 292000.0 0.41 0.5958 0.9995 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 E24 mock treatment 158670.0 -388000.0 -0.55 170100.0 -398000.0 -0.56 -0.7828 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F01 compound treatment 780787.0 234000.0 0.33 859562.0 291000.0 0.41 0.5227 0.9951 1016959 Maybridge1_008735 NC(=S)c1ccc2ccccc2c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F02 compound treatment 813135.0 266000.0 0.38 893179.0 325000.0 0.45 0.5884 0.996 2074356 Maybridge1_008736 Cc1ccc(cc1)S(=O)(=O)NC(=O)NNC(=O)c2cc(nn2Cc3ccc(F)cc3)C(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F03 compound treatment 839621.0 293000.0 0.42 921082.0 353000.0 0.49 0.6425 0.9965 2074357 Maybridge1_008737 Cc1n[nH]c(C)c1Sc2nc3ccccc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F04 compound treatment 840659.0 294000.0 0.42 926820.0 359000.0 0.5 0.6492 0.996 2074358 Maybridge1_008738 COc1ccc(OCCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F05 compound treatment 873734.0 327000.0 0.46 951197.0 383000.0 0.53 0.7065 0.9976 2074359 Maybridge1_008739 CCOC(=O)C(C(=O)OCC)c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F06 compound treatment 858486.0 312000.0 0.44 916092.0 348000.0 0.49 0.6566 0.999 1189493 Maybridge1_008740 Cc1ccc(cc1F)c2nc(cs2)c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F07 compound treatment 934308.0 388000.0 0.55 949177.0 381000.0 0.53 0.7654 0.9998 1724587 Maybridge1_008741 Nc1snnc1c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F08 compound treatment 898155.0 351000.0 0.5 891455.0 323000.0 0.45 0.6722 0.9987 2074360 Maybridge1_008742 CC(C)(C)c1ccc(cc1)c2nnc(SCc3ccc(OC(F)(F)F)cc3)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F09 compound treatment 926723.0 380000.0 0.54 974850.0 407000.0 0.57 0.7831 0.9997 2074361 Maybridge1_008743 CC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F10 compound treatment 891119.0 344000.0 0.49 967416.0 399000.0 0.56 0.74 0.9979 2074362 Maybridge1_008744 O/N=C/c1c(F)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F11 compound treatment 960183.0 413000.0 0.59 960564.0 392000.0 0.55 0.8027 0.9994 1291550 Maybridge1_008745 CC(C)Oc1ccc(C[C@H](NC(=O)C)C(=O)O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F12 compound treatment 908268.0 361000.0 0.51 978316.0 410000.0 0.57 0.768 0.9986 1334012 Maybridge1_008746 Fc1ccc(C(=O)N2CCN(CC2)c3ccc(C#N)cc3)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F13 compound treatment 947446.0 401000.0 0.57 919538.0 351000.0 0.49 0.7494 0.9972 2074363 Maybridge1_008747 FC(F)(F)c1ccc(cc1)C(=O)CSc2nncn2c3ccc(OCc4ccccc4)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F14 compound treatment 928898.0 382000.0 0.54 935794.0 368000.0 0.51 0.7468 0.9996 1460178 Maybridge1_008748 COc1ccc(NC(=O)Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F15 compound treatment 921820.0 375000.0 0.53 1025889.0 458000.0 0.64 0.8285 0.996 2074364 Maybridge1_008749 Clc1cc(Cl)cc(NC(=O)CSc2nnc(c3ccco3)n2c4ccc5OCCOc5c4)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F16 compound treatment 937010.0 390000.0 0.55 961827.0 394000.0 0.55 0.7806 1.0 1728052 Maybridge1_008750 COc1cccc(NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F17 compound treatment 939727.0 393000.0 0.56 1037106.0 469000.0 0.65 0.8576 0.9969 2074365 Maybridge1_008751 Cc1nnsc1C(=O)N2C[C@@H]3CCCC[C@@H]3C[C@@H]2C(=O)NC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F18 compound treatment 869947.0 323000.0 0.46 939947.0 372000.0 0.52 0.6916 0.9982 1246370 Maybridge1_008752 CC(C)(C)c1ccc(NC2CCN(Cc3ccccc3)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F19 compound treatment 914816.0 368000.0 0.52 988554.0 420000.0 0.59 0.7847 0.9984 1396461 Maybridge1_008753 CC(C)(C)c1cc(C(=O)O)n(Cc2ccc(Cl)cc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F20 compound treatment 894652.0 348000.0 0.49 945618.0 377000.0 0.53 0.7221 0.9995 2074366 Maybridge1_008754 Cn1cc(cc1C(=O)O)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F21 compound treatment 913268.0 366000.0 0.52 1064102.0 496000.0 0.69 0.8576 0.9903 2074367 Maybridge1_008755 CC(C)(C)c1cc(C(=O)NNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)n(Cc3ccc(F)cc3)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F22 compound treatment 831122.0 284000.0 0.4 927701.0 360000.0 0.5 0.6405 0.9943 1444849 Maybridge1_008756 CCOc1cc(N2CCOCC2)c(OCC)cc1NS(=O)(=O)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F23 mock treatment 879600.0 333000.0 0.47 948311.0 380000.0 0.53 0.7096 0.9984 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 F24 mock treatment 160032.0 -387000.0 -0.55 154531.0 -414000.0 -0.58 -0.7968 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G01 compound treatment 780552.0 234000.0 0.33 818227.0 250000.0 0.35 0.4817 0.9997 2074368 Maybridge1_008757 CC(C)(C)c1csc(n1)c2ccc(Oc3ccc(cn3)C(F)(F)F)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G02 compound treatment 756022.0 209000.0 0.3 817216.0 249000.0 0.35 0.456 0.997 2074369 Maybridge1_008758 Nc1nccc(n1)c2cc(no2)c3cccc(c3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G03 compound treatment 827774.0 281000.0 0.4 863089.0 295000.0 0.41 0.5734 0.9999 1505963 Maybridge1_008759 CC(C)(C)c1cc(C(=O)N)n(Cc2ccccc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G04 compound treatment 805592.0 259000.0 0.37 917800.0 350000.0 0.49 0.6051 0.9904 2074370 Maybridge1_008760 Nc1cc(O)nc(n1)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G05 compound treatment 861856.0 315000.0 0.45 870135.0 302000.0 0.42 0.6146 0.9995 2074371 Maybridge1_008761 COC(=O)c1c(C)noc1c2snnc2C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G06 compound treatment 825664.0 279000.0 0.4 886228.0 318000.0 0.44 0.5941 0.9984 2074372 Maybridge1_008762 CC(=O)c1c(C)onc1c2cccc(Cl)c2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G07 compound treatment 899621.0 353000.0 0.5 830329.0 262000.0 0.37 0.6134 0.9879 2074373 Maybridge1_008763 NNC(=O)c1ccc(OC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G08 compound treatment 868195.0 321000.0 0.46 883447.0 315000.0 0.44 0.6341 0.9998 2074374 Maybridge1_008764 Clc1ccc(Oc2ccc(C#N)cn2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G09 compound treatment 938167.0 391000.0 0.56 948096.0 380000.0 0.53 0.7683 0.9997 2074375 Maybridge1_008765 COC(=O)c1noc(C)c1c2cc[nH]n2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G10 compound treatment 883357.0 337000.0 0.48 889591.0 321000.0 0.45 0.6554 0.9995 2074376 Maybridge1_008766 NC(=S)c1ccc(OCC(F)(F)F)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G11 compound treatment 925141.0 378000.0 0.54 937930.0 370000.0 0.52 0.7451 0.9998 1445942 Maybridge1_008767 CC(C)(C)c1cc(C(=O)NN)n(Cc2ccc(F)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G12 compound treatment 908954.0 362000.0 0.52 882881.0 315000.0 0.44 0.6746 0.9968 1298876 Maybridge1_008768 CCOC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G13 compound treatment 899276.0 353000.0 0.5 883899.0 316000.0 0.44 0.6658 0.9979 2074377 Maybridge1_008769 Clc1ccc(Sc2c[nH]nc2c3ccc(Cl)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G14 compound treatment 924797.0 378000.0 0.54 895349.0 327000.0 0.46 0.7028 0.9967 2074378 Maybridge1_008770 COC(=O)c1cc(C)nc(O)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G15 compound treatment 941505.0 395000.0 0.56 946052.0 378000.0 0.53 0.7696 0.9995 2074379 Maybridge1_008771 Cc1onc2c(=O)n(C)nc(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G16 compound treatment 932089.0 385000.0 0.55 921505.0 353000.0 0.49 0.7359 0.9986 2074380 Maybridge1_008772 CCOC(=O)c1cc(C#N)c(O)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G17 compound treatment 928602.0 382000.0 0.54 886455.0 318000.0 0.44 0.6978 0.995 2074381 Maybridge1_008773 CCOC(=O)c1nc(sc1c2cc[nH]n2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G18 compound treatment 862356.0 316000.0 0.45 890831.0 323000.0 0.45 0.6356 1.0 2074382 Maybridge1_008774 NC(=S)Nc1ccccc1F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G19 compound treatment 905484.0 359000.0 0.51 928986.0 361000.0 0.5 0.7165 1.0 2074383 Maybridge1_008775 CC(=O)c1cc(no1)c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G20 compound treatment 845836.0 299000.0 0.43 898322.0 330000.0 0.46 0.6263 0.9992 1671789 Maybridge1_008776 Clc1ccc2nc(sc2c1)N3CCNCC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G21 compound treatment 880682.0 334000.0 0.47 834397.0 266000.0 0.37 0.5983 0.9926 2074384 Maybridge1_008777 Cc1onc(c1c2ccn[nH]2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G22 compound treatment 876040.0 329000.0 0.47 907723.0 340000.0 0.47 0.666 1.0 2074385 Maybridge1_008778 Nc1ccccc1Sc2ncc(s2)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G23 mock treatment 849977.0 303000.0 0.43 862711.0 295000.0 0.41 0.5954 0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 G24 mock treatment 152771.0 -394000.0 -0.56 157905.0 -410000.0 -0.57 -0.8008 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H01 compound treatment 756631.0 210000.0 0.3 851182.0 283000.0 0.39 0.4901 0.9905 2074386 Maybridge1_008779 CCC(C)Cn1c(O)nnc1S 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H02 compound treatment 753961.0 207000.0 0.29 802592.0 234000.0 0.33 0.4395 0.9987 1214172 Maybridge1_008780 CCOC(=O)CSc1nnc(c2cc(nn2Cc3cccc(C)c3)C(C)(C)C)n1C4CCCCC4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H03 compound treatment 808343.0 262000.0 0.37 866567.0 298000.0 0.42 0.5573 0.9984 2074387 Maybridge1_008781 Cc1n[nH]c(C)c1Sc2ccc(Cl)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H04 compound treatment 803112.0 256000.0 0.36 823088.0 255000.0 0.36 0.5092 0.9999 2074388 Maybridge1_008782 COc1ccc(OCCNC(=O)c2cccs2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H05 compound treatment 843111.0 296000.0 0.42 916971.0 349000.0 0.49 0.642 0.9974 2074389 Maybridge1_008783 Clc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)n2c4ccc(OCc5ccccc5)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H06 compound treatment 864364.0 318000.0 0.45 867587.0 299000.0 0.42 0.6146 0.9992 2074390 Maybridge1_008784 FC(F)(F)c1ccc(Oc2ccc(cc2)c3nc(cs3)c4ccc5OCCOc5c4)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H07 compound treatment 892272.0 346000.0 0.49 944684.0 377000.0 0.53 0.7187 0.9994 2074391 Maybridge1_008785 FC(F)(F)c1cc(Cc2nnn[nH]2)cc(c1)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H08 compound treatment 883244.0 336000.0 0.48 924477.0 356000.0 0.5 0.6897 0.9998 2074392 Maybridge1_008786 COc1ccc(OCCNC(=O)c2ccccc2C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H09 compound treatment 924690.0 378000.0 0.54 981917.0 414000.0 0.58 0.7881 0.9994 2074393 Maybridge1_008787 COc1cccc(c1)C2(C)C(C#N)C(=O)NC(=O)C2C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H10 compound treatment 873561.0 327000.0 0.46 937037.0 369000.0 0.51 0.6924 0.9987 2074394 Maybridge1_008788 FC(F)(F)Oc1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(C#N)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H11 compound treatment 917502.0 371000.0 0.53 994765.0 427000.0 0.59 0.7935 0.9982 1183230 Maybridge1_008789 COc1ccccc1OCC(=O)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H12 compound treatment 880666.0 334000.0 0.47 931424.0 363000.0 0.51 0.694 0.9995 1718196 Maybridge1_008790 O=C(N1CCN(CC1)c2ccc(C#N)cc2)c3cccs3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H13 compound treatment 943169.0 396000.0 0.56 985203.0 417000.0 0.58 0.8099 0.9999 2074395 Maybridge1_008791 CC1=N/C(=C\c2ccc(Br)cc2)/C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H14 compound treatment 914047.0 367000.0 0.52 915919.0 348000.0 0.49 0.7123 0.9993 2074396 Maybridge1_008792 Clc1ccc(NC(=O)Cc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H15 compound treatment 914262.0 367000.0 0.52 1047277.0 479000.0 0.67 0.842 0.9926 2074397 Maybridge1_008793 FC(F)(F)c1ccc(NC(=O)CSc2nnc(c3ccco3)n2c4ccc5OCCOc5c4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H16 compound treatment 886431.0 340000.0 0.48 934706.0 367000.0 0.51 0.703 0.9996 1779629 Maybridge1_008794 [O-][N+](=O)c1cccc(NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H17 compound treatment 918829.0 372000.0 0.53 954366.0 386000.0 0.54 0.755 1.0 1298245 Maybridge1_008795 Clc1cc(Cl)cc(NC(=O)N2CCCN(CC2)c3ccc(C#N)cn3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H18 compound treatment 912475.0 366000.0 0.52 973846.0 406000.0 0.57 0.7678 0.9991 1464949 Maybridge1_008796 COc1ccc(NC2CCN(Cc3ccccc3)CC2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H19 compound treatment 876112.0 329000.0 0.47 908748.0 341000.0 0.48 0.6671 1.0 1155555 Maybridge1_008797 CC(C)(C)c1cc(C(=O)O)n(Cc2ccc(F)cc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H20 compound treatment 840505.0 294000.0 0.42 881407.0 313000.0 0.44 0.6043 0.9997 1709464 Maybridge1_008798 Cn1cc(NC(=O)OC(C)(C)C)cc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H21 compound treatment 864542.0 318000.0 0.45 952192.0 384000.0 0.54 0.6983 0.9964 2074398 Maybridge1_008799 CC(C)(C)c1cc(c2nnc(S)n2c3ccccc3)n(Cc4ccc(Cl)cc4Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H22 compound treatment 846882.0 300000.0 0.43 915415.0 347000.0 0.48 0.6442 0.998 1672 Maybridge1_008800 OC(=O)CCc1nc(c(o1)c2ccccc2)c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H23 mock treatment 835545.0 289000.0 0.41 912456.0 344000.0 0.48 0.6299 0.997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 H24 mock treatment 159089.0 -388000.0 -0.55 152834.0 -415000.0 -0.58 -0.7994 -0.9997 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I01 compound treatment 780470.0 234000.0 0.33 838674.0 271000.0 0.38 0.5018 0.998 2074399 Maybridge1_008801 Cc1nc(sc1C(=O)O)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I02 compound treatment 1090222.0 543000.0 0.77 1285665.0 717000.0 1.0 1.2541 0.9918 2074400 Maybridge1_008802 CCO/C(=C(\C#N)/C(=S)N)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I03 compound treatment 853658.0 307000.0 0.44 886390.0 318000.0 0.44 0.6224 1.0 2074401 Maybridge1_008803 COC(=O)c1c(C)noc1c2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I04 compound treatment 817430.0 271000.0 0.38 880154.0 312000.0 0.44 0.5798 0.9981 2074402 Maybridge1_008804 CCOC(=O)c1cnc(nc1O)c2ccccn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I05 compound treatment 898565.0 352000.0 0.5 920117.0 352000.0 0.49 0.7008 1.0 2074403 Maybridge1_008805 NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I06 compound treatment 811755.0 265000.0 0.38 899395.0 331000.0 0.46 0.5931 0.9949 2074404 Maybridge1_008806 COC(OC)c1nc(SCc2c(Cl)cccc2Cl)ncc1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I07 compound treatment 902116.0 355000.0 0.51 938157.0 370000.0 0.52 0.7222 0.9999 2074405 Maybridge1_008807 NNC(=O)c1ccccc1OC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I08 compound treatment 878927.0 332000.0 0.47 883171.0 315000.0 0.44 0.6447 0.9993 2074406 Maybridge1_008808 N/C(=N\O)/c1ccc(Oc2ccc(Cl)cc2)nc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I09 compound treatment 926635.0 380000.0 0.54 879993.0 312000.0 0.43 0.6895 0.9942 2074407 Maybridge1_008809 CC(=O)c1csc(n1)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I10 compound treatment 894204.0 347000.0 0.49 893286.0 325000.0 0.45 0.67 0.9991 2074408 Maybridge1_008810 CSC(=C(C#N)C#N)/N=C(/N)\C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I11 compound treatment 895532.0 349000.0 0.5 933180.0 365000.0 0.51 0.7107 0.9999 2074409 Maybridge1_008811 CCOC(=O)c1cc(n[nH]1)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I12 compound treatment 892048.0 345000.0 0.49 907441.0 339000.0 0.47 0.6818 0.9998 1415037 Maybridge1_008812 C1CN(CCN1)C2c3ccccc3-c4ccccc24 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I13 compound treatment 936664.0 390000.0 0.55 922146.0 354000.0 0.49 0.7412 0.9983 2074410 Maybridge1_008813 Cn1ccnc1Sc2cnc(S)nc2c3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I14 compound treatment 928076.0 381000.0 0.54 943289.0 375000.0 0.52 0.7534 0.9998 1116774 Maybridge1_008814 OC(c1ccccc1)(c2ccccc2)c3ccncc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I15 compound treatment 965966.0 419000.0 0.6 948889.0 381000.0 0.53 0.797 0.9983 2074411 Maybridge1_008815 CCOC(=O)c1cc(on1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I16 compound treatment 915111.0 368000.0 0.52 914029.0 346000.0 0.48 0.7115 0.9992 2074412 Maybridge1_008816 Cc1nc(nc(Sc2nnc([nH]2)c3cc(Cl)cc(Cl)c3)c1C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I17 compound treatment 941974.0 395000.0 0.56 969448.0 401000.0 0.56 0.7931 1.0 2074413 Maybridge1_008817 CS(=O)(=O)CC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I18 compound treatment 898272.0 352000.0 0.5 910649.0 342000.0 0.48 0.6912 0.9997 2074414 Maybridge1_008818 NC(=S)Nc1cc(ccc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I19 compound treatment 903686.0 357000.0 0.51 959572.0 391000.0 0.55 0.7449 0.9993 1073042 Maybridge1_008819 COC(OC)c1cc(O)nc(S)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I20 compound treatment 873267.0 326000.0 0.46 923656.0 355000.0 0.5 0.6789 0.9995 2074415 Maybridge1_008820 FC(F)(F)Oc1ccccc1S(=O)(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I21 compound treatment 917015.0 370000.0 0.53 883325.0 315000.0 0.44 0.6831 0.996 1639470 Maybridge1_008821 CC(C)NC(=O)n1nccc1c2c(C)onc2c3ccc(Cl)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I22 compound treatment 856027.0 309000.0 0.44 882244.0 314000.0 0.44 0.6207 1.0 2074416 Maybridge1_008822 COc1cc(OC)nc(n1)S(=O)(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I23 mock treatment 877529.0 331000.0 0.47 906665.0 338000.0 0.47 0.6664 1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 I24 mock treatment 141256.0 -406000.0 -0.58 156333.0 -412000.0 -0.57 -0.8139 -1.0 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J01 compound treatment 761374.0 215000.0 0.31 829331.0 261000.0 0.36 0.4734 0.9961 2074417 Maybridge1_008823 CCOC(=O)c1cc(C)nn1Cc2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J02 compound treatment 768635.0 222000.0 0.32 881607.0 313000.0 0.44 0.5322 0.9872 1159897 Maybridge1_008824 Cc1cccc(Cn2nc(cc2c3nnc(SCC(=O)O)n3C4CCCCC4)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J03 compound treatment 935721.0 389000.0 0.55 1065511.0 497000.0 0.69 0.8816 0.9937 2074418 Maybridge1_008825 CCOC(=O)c1sc2nc(ccc2c1N)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J04 compound treatment 791383.0 245000.0 0.35 919477.0 351000.0 0.49 0.5924 0.9859 2074419 Maybridge1_008826 OCCCCNC(=O)OCC1c2ccccc2-c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J05 compound treatment 810672.0 264000.0 0.38 928425.0 360000.0 0.5 0.6207 0.9897 2074420 Maybridge1_008827 N/C(=N\O)/Cc1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J06 compound treatment 831509.0 285000.0 0.4 853199.0 285000.0 0.4 0.5674 1.0 2074421 Maybridge1_008828 FC(F)(F)c1ccc(cc1)c2nc(cs2)c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J07 compound treatment 869665.0 323000.0 0.46 909903.0 342000.0 0.48 0.6617 0.9998 2074422 Maybridge1_008829 CCOC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)c(c1)[N+](=O)[O-] 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J08 compound treatment 856696.0 310000.0 0.44 900114.0 332000.0 0.46 0.639 0.9997 2074423 Maybridge1_008830 C1COc2cc(ccc2O1)c3csc(N/N=C/c4cccs4)n3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J09 compound treatment 899369.0 353000.0 0.5 954412.0 386000.0 0.54 0.7355 0.9994 2074424 Maybridge1_008831 CC(=O)c1cc(no1)c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J10 compound treatment 894528.0 348000.0 0.49 953291.0 385000.0 0.54 0.7295 0.9991 1537006 Maybridge1_008832 Cc1onc(c1C(=O)N2CCN(CC2)c3nc(ns3)c4cccs4)c5c(Cl)cccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J11 compound treatment 902049.0 355000.0 0.51 919783.0 352000.0 0.49 0.704 0.9999 2074425 Maybridge1_008833 CC(C)c1ccc(NC(=O)CSc2nncn2c3ccc4OCCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J12 compound treatment 875389.0 329000.0 0.47 911742.0 344000.0 0.48 0.6693 0.9999 1574772 Maybridge1_008834 O=C(N1CCN(CC1)c2nc(ns2)c3cccs3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J13 compound treatment 897897.0 351000.0 0.5 887009.0 319000.0 0.44 0.6675 0.9983 2074426 Maybridge1_008835 CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C(=O)COc3ccc(Cl)cc3Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J14 compound treatment 890847.0 344000.0 0.49 935720.0 368000.0 0.51 0.7085 0.9997 1110808 Maybridge1_008836 COc1ccc(NC(=O)c2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J15 compound treatment 923020.0 376000.0 0.54 963076.0 395000.0 0.55 0.7678 0.9999 2074427 Maybridge1_008837 Cc1nnc(SCc2c(Cl)cccc2Cl)n1c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J16 compound treatment 873702.0 327000.0 0.46 944479.0 376000.0 0.52 0.6999 0.9982 1427190 Maybridge1_008838 Fc1cccc(F)c1C(=O)Nc2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J17 compound treatment 888193.0 341000.0 0.49 899561.0 331000.0 0.46 0.6701 0.9997 1528180 Maybridge1_008839 Fc1ccc(NC(=O)N2CCCN(CC2)c3ccc(C#N)cn3)c(F)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J18 compound treatment 859272.0 313000.0 0.44 927924.0 360000.0 0.5 0.669 0.9982 2074428 Maybridge1_008840 CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J19 compound treatment 861449.0 315000.0 0.45 898056.0 330000.0 0.46 0.6418 0.9999 1249554 Maybridge1_008841 Cc1cc(C)c(Cn2nc(cc2C(=O)O)C(C)(C)C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J20 compound treatment 842215.0 295000.0 0.42 919214.0 351000.0 0.49 0.6433 0.9971 2074429 Maybridge1_008842 [O-][N+](=O)c1ccc(cc1)N2CCN(Cc3ccccc3)CC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J21 compound treatment 888396.0 342000.0 0.49 946432.0 378000.0 0.53 0.7166 0.9992 1524382 Maybridge1_008843 Cc1cccc(Cn2nc(cc2c3nnc(S)n3C4CCCCC4)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J22 compound treatment 828620.0 282000.0 0.4 866870.0 299000.0 0.42 0.578 0.9998 1377203 Maybridge1_008844 Nc1cc(F)ccc1n2ccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J23 mock treatment 858935.0 312000.0 0.44 921961.0 354000.0 0.49 0.6628 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 J24 mock treatment 164809.0 -382000.0 -0.54 162662.0 -406000.0 -0.57 -0.784 -0.9998 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K01 compound treatment 769082.0 222000.0 0.32 812458.0 244000.0 0.34 0.4645 0.9993 2074430 Maybridge1_008845 Cc1nc(sc1C(=O)NN)c2ccc(cc2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K02 compound treatment 763385.0 217000.0 0.31 843222.0 275000.0 0.38 0.4891 0.9941 1601358 Maybridge1_008846 Cc1noc(N)c1C(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K03 compound treatment 823039.0 276000.0 0.39 870724.0 303000.0 0.42 0.5762 0.9994 2074431 Maybridge1_008847 COC(=O)c1c(C)noc1c2ccno2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K04 compound treatment 792481.0 246000.0 0.35 852331.0 284000.0 0.4 0.5273 0.998 2074432 Maybridge1_008848 O/N=C/c1ccc(OC(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K05 compound treatment 848601.0 302000.0 0.43 875255.0 307000.0 0.43 0.6064 1.0 2074433 Maybridge1_008849 NNC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K06 compound treatment 850560.0 304000.0 0.43 845436.0 277000.0 0.39 0.5789 0.9985 2074434 Maybridge1_008850 Cc1nc(COc2ccccc2)nc(O)c1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K07 compound treatment 862395.0 316000.0 0.45 924460.0 356000.0 0.5 0.6688 0.9987 2074435 Maybridge1_008851 CC(=O)c1csc(CS(=O)(=O)c2ccccn2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K08 compound treatment 853537.0 307000.0 0.44 840440.0 272000.0 0.38 0.577 0.9976 2074436 Maybridge1_008852 O/N=C/c1c(Cl)cccc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K09 compound treatment 911209.0 364000.0 0.52 919486.0 351000.0 0.49 0.7129 0.9996 2074437 Maybridge1_008853 COC(=O)c1noc(C)c1/C(=N/O)/C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K10 compound treatment 889330.0 343000.0 0.49 848602.0 280000.0 0.39 0.621 0.9941 2074438 Maybridge1_008854 CNC(=S)NNC(=O)c1ccc(Cl)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K11 compound treatment 903340.0 357000.0 0.51 891488.0 323000.0 0.45 0.6774 0.9983 2074439 Maybridge1_008855 CNc1ncc(cc1[N+](=O)[O-])C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K12 compound treatment 871165.0 324000.0 0.46 865023.0 297000.0 0.41 0.619 0.9985 2074440 Maybridge1_008856 NC(=S)CCn1cccc(c1=O)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K13 compound treatment 922085.0 375000.0 0.53 907006.0 339000.0 0.47 0.7116 0.9982 1465283 Maybridge1_008857 Cc1ccc(Oc2c(C)[nH]c(=S)[nH]c2=O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K14 compound treatment 902782.0 356000.0 0.51 825919.0 258000.0 0.36 0.6122 0.9859 2074441 Maybridge1_008858 c1ccc-2c(c1)C(c3ccccc32)c4ccncc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K15 compound treatment 904483.0 358000.0 0.51 911638.0 343000.0 0.48 0.6984 0.9995 2074442 Maybridge1_008859 FC(F)(F)C(=O)/C(=N\Nc1ccc(Cl)cc1Cl)/C(=O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K16 compound treatment 892114.0 345000.0 0.49 906946.0 339000.0 0.47 0.6814 0.9998 2074443 Maybridge1_008860 CCOC(=O)c1sc2nc(c(cc2c1N)C(=O)OCC)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K17 compound treatment 885017.0 338000.0 0.48 949420.0 381000.0 0.53 0.7161 0.9987 2074444 Maybridge1_008861 CC(C)(C)S(=O)(=O)CC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K18 compound treatment 874271.0 328000.0 0.47 893999.0 326000.0 0.45 0.6507 0.9999 1459332 Maybridge1_008862 O=c1oc2ccccc2n1Cc3cccc(C#N)c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K19 compound treatment 879904.0 333000.0 0.47 939919.0 372000.0 0.52 0.7016 0.999 2074445 Maybridge1_008863 O/N=C/c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K20 compound treatment 847878.0 301000.0 0.43 901770.0 334000.0 0.47 0.6318 0.9991 2074446 Maybridge1_008864 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K21 compound treatment 906717.0 360000.0 0.51 942874.0 375000.0 0.52 0.7315 0.9999 2074447 Maybridge1_008865 CC(=O)c1c(C)onc1c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K22 compound treatment 830979.0 284000.0 0.4 880651.0 312000.0 0.44 0.594 0.9993 2074448 Maybridge1_008866 COc1ccc(cc1[N+](=O)[O-])C(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K23 mock treatment 859335.0 313000.0 0.44 896130.0 328000.0 0.46 0.6377 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 K24 mock treatment 164663.0 -382000.0 -0.54 151566.0 -417000.0 -0.58 -0.7951 -0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L01 compound treatment 731364.0 185000.0 0.26 829658.0 261000.0 0.36 0.4435 0.987 2074449 Maybridge1_008867 CCOC(=O)c1cc(C)n(Cc2c(Cl)cccc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L02 compound treatment 735711.0 189000.0 0.27 838303.0 270000.0 0.38 0.4564 0.9863 2074450 Maybridge1_008868 COc1ccc(OCCNC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L03 compound treatment 870904.0 324000.0 0.46 1022176.0 454000.0 0.63 0.7737 0.9878 1382829 Maybridge1_008869 O=c1[nH]c(ccc1C#N)c2ccco2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L04 compound treatment 770636.0 224000.0 0.32 854209.0 286000.0 0.4 0.5072 0.9937 2074451 Maybridge1_008870 OCCCCCCNC(=O)OCC1c2ccccc2-c3ccccc13 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L05 compound treatment 808919.0 262000.0 0.37 910873.0 343000.0 0.48 0.6016 0.9924 2074452 Maybridge1_008871 NNS(=O)(=O)c1ccc(Cl)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L06 compound treatment 793151.0 246000.0 0.35 877688.0 310000.0 0.43 0.553 0.9946 2074453 Maybridge1_008872 Cc1onc(c1c2nc(cs2)c3ccc4OCCOc4c3)c5c(Cl)cccc5Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L07 compound treatment 818227.0 271000.0 0.39 939810.0 372000.0 0.52 0.6395 0.9895 1925488 Maybridge1_008873 CC(C)(C)c1ccc(cc1)c2nnc(S)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L08 compound treatment 889788.0 343000.0 0.49 914350.0 346000.0 0.48 0.6863 1.0 1408544 Maybridge1_008874 Clc1ccc(cc1)S(=O)(=O)Cc2nc(cs2)c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L09 compound treatment 875016.0 328000.0 0.47 872660.0 304000.0 0.42 0.6304 0.9989 1239086 Maybridge1_008875 COc1ccc(OCC(=O)N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L10 compound treatment 816787.0 270000.0 0.38 836146.0 268000.0 0.37 0.5358 0.9999 2074454 Maybridge1_008876 FC(F)(F)Oc1ccc(cc1)C(=O)N2CCN(CC2)c3nc(ns3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L11 compound treatment 876995.0 330000.0 0.47 926544.0 358000.0 0.5 0.6855 0.9995 2074455 Maybridge1_008877 FC(F)(F)c1cccc(NC(=O)CSc2nncn2c3ccc4OCCOc4c3)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L12 compound treatment 851655.0 305000.0 0.43 853945.0 286000.0 0.4 0.5884 0.9991 1175090 Maybridge1_008878 Cc1cccc(Cn2nc(cc2c3nnc(SCC(=O)c4ccccc4)o3)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L13 compound treatment 856407.0 310000.0 0.44 912784.0 345000.0 0.48 0.6512 0.999 2074456 Maybridge1_008879 CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C(=O)c3ccc(cc3)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L14 compound treatment 834881.0 288000.0 0.41 882598.0 314000.0 0.44 0.5998 0.9994 2074457 Maybridge1_008880 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L15 compound treatment 887033.0 340000.0 0.48 930133.0 362000.0 0.5 0.6991 0.9998 2074458 Maybridge1_008881 Cc1nnc(SCC(=O)c2ccc(Cl)cc2)n1c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L16 compound treatment 853771.0 307000.0 0.44 895116.0 327000.0 0.46 0.6311 0.9998 1026880 Maybridge1_008882 Clc1cccc(NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L17 compound treatment 833065.0 286000.0 0.41 960488.0 392000.0 0.55 0.6748 0.9894 1374727 Maybridge1_008883 Cc1ccccc1NC(=O)N2CCCN(CC2)c3ccc(C#N)cn3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L18 compound treatment 811816.0 265000.0 0.38 901072.0 333000.0 0.46 0.5948 0.9946 2074459 Maybridge1_008884 CCOC(=O)N1CCN(CC1)c2nc(c(cc2C#N)C(=O)OCC)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L19 compound treatment 853839.0 307000.0 0.44 921750.0 354000.0 0.49 0.6575 0.9982 1563500 Maybridge1_008885 Cc1cccc(Cn2nc(cc2C(=O)NN)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L20 compound treatment 830379.0 284000.0 0.4 884158.0 316000.0 0.44 0.5968 0.999 1602761 Maybridge1_008886 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)c3ccc(C)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L21 compound treatment 838484.0 292000.0 0.41 935856.0 368000.0 0.51 0.6559 0.9945 2074460 Maybridge1_008887 Cc1cc(Br)ccc1NC(=O)OC(C)(C)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L22 compound treatment 801393.0 255000.0 0.36 822135.0 254000.0 0.35 0.5065 0.9999 1564357 Maybridge1_008888 Cc1ccc(cc1)S(=O)(=O)n2ccc3cc(N)ccc23 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L23 mock treatment 816442.0 270000.0 0.38 902319.0 334000.0 0.47 0.6007 0.9953 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 L24 mock treatment 151891.0 -395000.0 -0.56 154762.0 -413000.0 -0.58 -0.8048 -0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M01 compound treatment 771478.0 225000.0 0.32 818040.0 250000.0 0.35 0.4724 0.9991 1296479 Maybridge1_008889 CC(C)(C)c1cc(C(=O)O)n(Cc2ccccc2)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M02 compound treatment 764225.0 217000.0 0.31 850874.0 283000.0 0.39 0.4975 0.9928 2074461 Maybridge1_008890 CCOC(=O)c1cc(C)n(C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M03 compound treatment 823657.0 277000.0 0.39 884425.0 316000.0 0.44 0.5903 0.9984 2074462 Maybridge1_008891 CSc1nn(CO)c(=S)s1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M04 compound treatment 782431.0 236000.0 0.34 785633.0 217000.0 0.3 0.4514 0.9988 2074463 Maybridge1_008892 NC(=S)c1ncc(cc1Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M05 compound treatment 842383.0 296000.0 0.42 894072.0 326000.0 0.45 0.6187 0.9992 2074464 Maybridge1_008893 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2nnc(S)o2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M06 compound treatment 815003.0 268000.0 0.38 850253.0 282000.0 0.39 0.5479 0.9999 2074465 Maybridge1_008894 COc1ccc(OCc2nc(C)c(Cl)c(O)n2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M07 compound treatment 865984.0 319000.0 0.45 900081.0 332000.0 0.46 0.6483 1.0 2074466 Maybridge1_008895 CC(=O)c1csc(Nc2c(C)cc(C)cc2C)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M08 compound treatment 832290.0 286000.0 0.41 877720.0 310000.0 0.43 0.5924 0.9995 2074467 Maybridge1_008896 NC(=N)CSc1ccccc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M09 compound treatment 876757.0 330000.0 0.47 868382.0 300000.0 0.42 0.6279 0.9984 2074468 Maybridge1_008897 C/C(=N\NC(=S)N)/c1csc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M10 compound treatment 875302.0 329000.0 0.47 844859.0 277000.0 0.39 0.6032 0.9955 2074469 Maybridge1_008898 Sc1nnc(c2ccc(Cl)cc2Cl)n1Cc3ccco3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M11 compound treatment 902699.0 356000.0 0.51 862387.0 294000.0 0.41 0.6481 0.9946 2074470 Maybridge1_008899 CCOC(=O)CSc1nc2cc(cnc2n1C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M12 compound treatment 847707.0 301000.0 0.43 866738.0 299000.0 0.42 0.5971 0.9999 2074471 Maybridge1_008900 COC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M13 compound treatment 892561.0 346000.0 0.49 865248.0 297000.0 0.41 0.6407 0.9964 2074472 Maybridge1_008901 CCn1nc(cc1C(=O)O)c2cccs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M14 compound treatment 872502.0 326000.0 0.46 894022.0 326000.0 0.45 0.6489 1.0 2074473 Maybridge1_008902 Nc1cc(ccc1N2CCC(CC2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M15 compound treatment 921829.0 375000.0 0.53 907039.0 339000.0 0.47 0.7113 0.9982 2074474 Maybridge1_008903 COC(OC)c1ccnc(SCc2ccc(Cl)cc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M16 compound treatment 866933.0 320000.0 0.46 816850.0 249000.0 0.35 0.5672 0.991 2074475 Maybridge1_008904 CCOC(=O)c1cc(C#N)c(Sc2ccccc2N)nc1C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M17 compound treatment 896296.0 350000.0 0.5 914582.0 346000.0 0.48 0.6931 0.9999 2074476 Maybridge1_008905 CC(=O)c1csc(n1)c2cc(C)on2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M18 compound treatment 866434.0 320000.0 0.45 878735.0 311000.0 0.43 0.6277 0.9997 2074477 Maybridge1_008906 NNC(=O)c1sccc1OCc2ncc(cc2Cl)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M19 compound treatment 853206.0 306000.0 0.44 943584.0 375000.0 0.52 0.6784 0.9958 2074478 Maybridge1_008907 COC(OC)c1nc(S)c(C#N)cc1C(=O)OC 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M20 compound treatment 838164.0 291000.0 0.41 882937.0 315000.0 0.44 0.6034 0.9996 1394218 Maybridge1_008908 CS(=O)(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M21 compound treatment 851657.0 305000.0 0.43 914400.0 346000.0 0.48 0.648 0.9986 1657037 Maybridge1_008909 Cc1onc(c1c2csc(n2)c3ccc(cc3)C(C)(C)C)c4ccccc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M22 compound treatment 813094.0 266000.0 0.38 878703.0 311000.0 0.43 0.5741 0.9978 2074479 Maybridge1_008910 Cc1ccc(cc1F)/C(=N/O)/N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M23 mock treatment 852755.0 306000.0 0.44 914764.0 347000.0 0.48 0.6495 0.9986 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 M24 mock treatment 671753.0 125000.0 0.18 617449.0 49300.0 0.07 0.1743 0.9145 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N01 compound treatment 748961.0 202000.0 0.29 855935.0 288000.0 0.4 0.4871 0.9866 2074480 Maybridge1_008911 CC(=O)c1csc(n1)c2ccc(C)c(F)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N02 compound treatment 745215.0 198000.0 0.28 860389.0 292000.0 0.41 0.4877 0.9839 2074481 Maybridge1_008912 FC(F)(F)c1ccc(cc1)c2nc(CSCc3csc(n3)c4ccc(cc4)C(F)(F)F)cs2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N03 compound treatment 767463.0 221000.0 0.31 914939.0 347000.0 0.48 0.5639 0.9781 1713251 Maybridge1_008913 Sc1n[nH]c(=O)n1c2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N04 compound treatment 765867.0 219000.0 0.31 857989.0 290000.0 0.4 0.5061 0.9917 1634679 Maybridge1_008914 N#CCc1nc(cs1)c2ccc3OCCOc3c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N05 compound treatment 803279.0 257000.0 0.36 930159.0 362000.0 0.5 0.6149 0.9873 1435896 Maybridge1_008915 NNC(=S)Nc1ccc(OCc2ccccc2)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N06 compound treatment 757349.0 211000.0 0.3 830258.0 262000.0 0.37 0.4702 0.9951 1721437 Maybridge1_008916 C1COc2cc(ccc2O1)c3csc(n3)c4cccs4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N07 compound treatment 829765.0 283000.0 0.4 903196.0 335000.0 0.47 0.615 0.9972 2074482 Maybridge1_008917 NC(=S)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N08 compound treatment 814465.0 268000.0 0.38 848154.0 280000.0 0.39 0.5453 0.9999 2074483 Maybridge1_008918 Cc1cc(C)c(Cn2nc(cc2C(=O)Nc3cccc(c3)C(F)(F)F)C(C)(C)C)c(C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N09 compound treatment 884393.0 338000.0 0.48 967515.0 399000.0 0.56 0.7333 0.9973 2074484 Maybridge1_008919 CC1=N/C(=C\c2cc(Cl)ccc2O)/C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N10 compound treatment 826782.0 280000.0 0.4 843774.0 276000.0 0.38 0.5534 0.9998 2074485 Maybridge1_008920 FC(F)(F)c1ccc(cc1)c2nc(cs2)C3(CC4CC5CC(C4)C3)C5 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N11 compound treatment 845244.0 298000.0 0.42 843560.0 275000.0 0.38 0.5717 0.9988 1585407 Maybridge1_008921 CC(C)(C)c1ccc(CSc2nncn2c3ccc(OCc4ccccc4)cc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N12 compound treatment 811230.0 264000.0 0.38 890051.0 322000.0 0.45 0.5834 0.9961 2074486 Maybridge1_008922 Clc1cc(Cl)cc(NC(=O)c2ccccc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N13 compound treatment 847722.0 301000.0 0.43 874542.0 306000.0 0.43 0.6048 1.0 2074487 Maybridge1_008923 Cc1ccc(CSc2nnc(c3ccco3)n2c4ccc5OCCOc5c4)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N14 compound treatment 844275.0 298000.0 0.42 919652.0 351000.0 0.49 0.6458 0.9973 1098613 Maybridge1_008924 COc1ccc(cc1)C(=O)Nc2cccnc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N15 compound treatment 894221.0 347000.0 0.49 917110.0 349000.0 0.49 0.6935 1.0 2074488 Maybridge1_008925 Cc1nnc(SCC(=O)c2ccccc2)n1c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N16 compound treatment 836921.0 290000.0 0.41 889280.0 321000.0 0.45 0.6084 0.9992 1065431 Maybridge1_008926 FC(F)(F)c1cccc(NC(=O)c2cccnc2)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N17 compound treatment 851129.0 304000.0 0.43 954225.0 386000.0 0.54 0.6868 0.9941 1283307 Maybridge1_008927 CNC(=S)N1CCCN(CC1)c2ccc(C#N)cn2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N18 compound treatment 830708.0 284000.0 0.4 911208.0 343000.0 0.48 0.6238 0.9964 2074489 Maybridge1_008928 CCOC(=O)N1CCN(CC1)c2cc(cc(n2)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N19 compound treatment 861680.0 315000.0 0.45 902419.0 334000.0 0.47 0.6463 0.9998 1566014 Maybridge1_008929 CC(C)(C)c1cc(C(=O)NN)n(Cc2ccc(Cl)cc2Cl)n1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N20 compound treatment 802706.0 256000.0 0.36 906470.0 338000.0 0.47 0.591 0.9918 1239894 Maybridge1_008930 Cc1ccc(cc1)C(=O)Nc2ccc(cc2)N3CCN(Cc4ccccc4)CC3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N21 compound treatment 841260.0 294000.0 0.42 871691.0 304000.0 0.42 0.5955 1.0 1359647 Maybridge1_008931 CC(=O)N[C@@H](Cc1cccs1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N22 compound treatment 792702.0 246000.0 0.35 871486.0 303000.0 0.42 0.5464 0.9955 1032778 Maybridge1_008932 CC(=O)c1cccc(OCC(=O)O)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N23 mock treatment 811311.0 265000.0 0.38 927523.0 359000.0 0.5 0.6204 0.99 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 N24 mock treatment 600978.0 54200.0 0.08 649552.0 81400.0 0.11 0.1348 0.9822 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O01 compound treatment 766763.0 220000.0 0.31 814583.0 246000.0 0.34 0.4642 0.9989 2074490 Maybridge1_008933 OC(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)o1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O02 compound treatment 728544.0 182000.0 0.26 819220.0 251000.0 0.35 0.4304 0.9889 1397180 Maybridge1_008934 Cc1c(sc2nc(nc(C)c12)c3ccccc3)C(=O)c4ccc(Cl)cc4 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O03 compound treatment 782000.0 235000.0 0.33 858546.0 290000.0 0.4 0.5229 0.9955 2074491 Maybridge1_008935 CN(C)/C=C(\C#N)/c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O04 compound treatment 761543.0 215000.0 0.31 833130.0 265000.0 0.37 0.4773 0.9955 2074492 Maybridge1_008936 C/C(=N\O)/c1sc2nc(nn2c1C)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O05 compound treatment 856444.0 310000.0 0.44 870475.0 302000.0 0.42 0.6095 0.9998 2074493 Maybridge1_008937 Cc1onc2c(=O)[nH]nc(C)c12 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O06 compound treatment 770770.0 224000.0 0.32 835683.0 268000.0 0.37 0.4891 0.9969 2074494 Maybridge1_008938 FC(F)(F)c1ccc(nc1)c2nnn[nH]2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O07 compound treatment 832742.0 286000.0 0.41 886008.0 318000.0 0.44 0.601 0.9991 2074495 Maybridge1_008939 C/C(=N\O)/c1csc(n1)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O08 compound treatment 794652.0 248000.0 0.35 842721.0 275000.0 0.38 0.52 0.9991 2074496 Maybridge1_008940 CSc1nc(COc2ccccc2Cl)nc(N)c1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O09 compound treatment 827525.0 281000.0 0.4 874376.0 306000.0 0.43 0.5843 0.9994 2074497 Maybridge1_008941 Cc1nc(sc1C(=O)O)c2ccccc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O10 compound treatment 804598.0 258000.0 0.37 841575.0 273000.0 0.38 0.5289 0.9998 2074498 Maybridge1_008942 Cn1c(S)nnc1c2ccc(Cl)cc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O11 compound treatment 841538.0 295000.0 0.42 866543.0 298000.0 0.42 0.5907 1.0 2074499 Maybridge1_008943 Cc1ccc(Oc2c(C)nc(nc2O)c3ccccc3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O12 compound treatment 810943.0 264000.0 0.38 812143.0 244000.0 0.34 0.5062 0.9988 2074500 Maybridge1_008944 CC(=O)C(Sc1ccc(Cl)cc1)C(=O)C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O13 compound treatment 892914.0 346000.0 0.49 892683.0 325000.0 0.45 0.6681 0.9991 2074501 Maybridge1_008945 CCOC(=O)c1cc(C#N)c(S)nc1C 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O14 compound treatment 830736.0 284000.0 0.4 828192.0 260000.0 0.36 0.542 0.9986 2074502 Maybridge1_008946 CC(=O)Nc1ccc(Br)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O15 compound treatment 881889.0 335000.0 0.48 885806.0 318000.0 0.44 0.6502 0.9993 1127840 Maybridge1_008947 Cc1ccc(Oc2c(C)nc(N)nc2O)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O16 compound treatment 819666.0 273000.0 0.39 858126.0 290000.0 0.4 0.5604 0.9998 1116550 Maybridge1_008948 COc1ccccc1NC(=S)N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O17 compound treatment 869908.0 323000.0 0.46 897095.0 329000.0 0.46 0.6493 1.0 2074503 Maybridge1_008949 Cc1cc(/C=N/NS(=O)(=O)c2ccc(F)c(Cl)c2)no1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O18 compound treatment 824446.0 278000.0 0.39 873204.0 305000.0 0.43 0.58 0.9993 2074504 Maybridge1_008950 CC(C)(C)NC(=O)O/N=C(\N)/c1ccc(NS(=O)(=O)C)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O19 compound treatment 857388.0 311000.0 0.44 869439.0 301000.0 0.42 0.6095 0.9997 2074505 Maybridge1_008951 CC(=O)c1cc(no1)c2ccc(Cl)c(Cl)c2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O20 compound treatment 815829.0 269000.0 0.38 854897.0 287000.0 0.4 0.5533 0.9998 1450208 Maybridge1_008952 CC(C)(C)NC(=O)N1CCN(CC1)c2nc3ccc(Cl)cc3s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O21 compound treatment 839263.0 292000.0 0.42 865030.0 297000.0 0.41 0.5869 1.0 2074506 Maybridge1_008953 N/C(=N\O)/c1ccc(OCc2ncc(cc2Cl)C(F)(F)F)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O22 compound treatment 787215.0 240000.0 0.34 862018.0 294000.0 0.41 0.5316 0.9959 2074507 Maybridge1_008954 FC(F)(F)COc1ncccc1C#N 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O23 mock treatment 827468.0 281000.0 0.4 875103.0 307000.0 0.43 0.585 0.9994 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 O24 mock treatment 550637.0 3870.0 0.01 326497.0 -242000.0 -0.34 -0.2345 -0.6955 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P01 compound treatment 735038.0 188000.0 0.27 788308.0 220000.0 0.31 0.4064 0.9977 1049753 Maybridge1_008955 CC(=O)Nc1ccc(C#N)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P02 compound treatment 751521.0 205000.0 0.29 854406.0 286000.0 0.4 0.4882 0.988 2074508 Maybridge1_008956 Cc1cccc(Cn2nc(cc2c3nnc(SCc4c(F)cccc4Cl)n3C5CCCCC5)C(C)(C)C)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P03 compound treatment 771614.0 225000.0 0.32 842787.0 275000.0 0.38 0.4969 0.996 2074509 Maybridge1_008957 CCOC(=O)c1cc(C#N)c(nc1C(F)(F)F)N2CCCNCC2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P04 compound treatment 754285.0 208000.0 0.3 846704.0 279000.0 0.39 0.4834 0.9908 2074510 Maybridge1_008958 FC(F)(F)Oc1ccc(cc1)c2nc(cs2)c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P05 compound treatment 764703.0 218000.0 0.31 861495.0 293000.0 0.41 0.5084 0.9906 1439285 Maybridge1_008959 Sc1nncn1c2ccc(OCc3ccccc3)cc2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P06 compound treatment 769873.0 223000.0 0.32 835669.0 267000.0 0.37 0.4882 0.9967 1609883 Maybridge1_008960 CCOC(=O)C1CCN(Cc2c(F)cccc2Cl)CC1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P07 compound treatment 776754.0 230000.0 0.33 844113.0 276000.0 0.38 0.5034 0.9967 2074511 Maybridge1_008961 N/C(=N\O)/Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P08 compound treatment 788559.0 242000.0 0.34 818567.0 250000.0 0.35 0.4901 1.0 1299675 Maybridge1_008962 COc1ccc(OCc2nc(cs2)c3ccc4OCCOc4c3)cc1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P09 compound treatment 777141.0 230000.0 0.33 841384.0 273000.0 0.38 0.5011 0.9972 2074512 Maybridge1_008963 CC1=N/C(=C\c2cc(Cl)cc(Br)c2O)/C(=O)O1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P10 compound treatment 781247.0 234000.0 0.33 823454.0 255000.0 0.36 0.4875 0.9995 2074513 Maybridge1_008964 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NC(Cc2ccc(cc2)[N+](=O)[O-])C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P11 compound treatment 776048.0 229000.0 0.33 828334.0 260000.0 0.36 0.4871 0.9986 2074514 Maybridge1_008965 Fc1cccc(Cl)c1CSc2nncn2c3ccc(OCc4ccccc4)cc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P12 compound treatment 793705.0 247000.0 0.35 834808.0 267000.0 0.37 0.5113 0.9996 2074515 Maybridge1_008966 Clc1ccc(NC(=O)c2ccccc2)cc1Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P13 compound treatment 791357.0 245000.0 0.35 824248.0 256000.0 0.36 0.4985 0.9999 2074516 Maybridge1_008967 Clc1ccc(CSc2nnc(c3ccco3)n2c4ccc5OCCOc5c4)c(Cl)c1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P14 compound treatment 804558.0 258000.0 0.37 847395.0 279000.0 0.39 0.5346 0.9995 1008239 Maybridge1_008968 Clc1ccccc1NC(=O)c2ccccc2Cl 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P15 compound treatment 806049.0 259000.0 0.37 878367.0 310000.0 0.43 0.5666 0.9968 2074517 Maybridge1_008969 Cc1nnc(SCC(=O)Nc2ccccc2Cl)n1c3ccc4OCCOc4c3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P16 compound treatment 795785.0 249000.0 0.35 869947.0 302000.0 0.42 0.548 0.9963 1927016 Maybridge1_008970 COc1ccccc1C(=O)Nc2cccc(c2)C(F)(F)F 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P17 compound treatment 817576.0 271000.0 0.39 884830.0 317000.0 0.44 0.5846 0.9977 2074518 Maybridge1_008971 CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NN 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P18 compound treatment 808032.0 261000.0 0.37 887710.0 320000.0 0.45 0.5778 0.9959 2074519 Maybridge1_008972 OC[C@@H]1Cc2ccccc2CN1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P19 compound treatment 806500.0 260000.0 0.37 874271.0 306000.0 0.43 0.5631 0.9974 2074520 Maybridge1_008973 CCCCNC(=O)O/N=C(\N)/Cc1cccs1 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P20 compound treatment 797521.0 251000.0 0.36 873394.0 305000.0 0.43 0.5532 0.9961 1681940 Maybridge1_008974 CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)Cc3ccccc3 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P21 compound treatment 794528.0 248000.0 0.35 866629.0 298000.0 0.42 0.5435 0.9966 1218670 Maybridge1_008975 CC(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)O 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P22 compound treatment 796481.0 250000.0 0.36 866823.0 299000.0 0.42 0.5456 0.9968 2074521 Maybridge1_008976 COc1ccccc1NS(=O)(=O)c2ccc(Cl)s2 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P23 mock treatment 793040.0 246000.0 0.35 827072.0 259000.0 0.36 0.503 0.9999 299.0543 raw{Pol(s)}(299.0543) CMVPolymeraseBindingAssay 299.0543.566 P24 mock treatment 556660.0 9890.0 0.01 634987.0 66800.0 0.09 0.0758 0.8047