ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A01 compound treatment 673813.0 206000.0 0.43 567907.0 107000.0 0.23 0.464 0.9586 1647163 ChemDiv1_021473 CC1(C)CC(=O)C2=C(C1)Nc3ccc4ccccc4c3C2c5ccccc5F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A02 compound treatment 761401.0 294000.0 0.61 577736.0 116000.0 0.25 0.6069 0.9243 1628847 ChemDiv1_021474 Cc1ccc(cc1)N2CCN(CC(O)Cn3c4ccccc4c5ccccc35)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A03 compound treatment 705655.0 238000.0 0.49 584051.0 123000.0 0.27 0.5352 0.9583 1980022 ChemDiv1_021475 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(OC)cc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A04 compound treatment 675557.0 208000.0 0.43 580824.0 119000.0 0.26 0.4863 0.9706 1251366 ChemDiv1_021476 Fc1cccc(Cl)c1C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A05 compound treatment 693326.0 226000.0 0.47 607580.0 146000.0 0.32 0.5532 0.9823 1980023 ChemDiv1_021477 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A06 compound treatment 702066.0 234000.0 0.48 611871.0 151000.0 0.33 0.5725 0.9815 1152034 ChemDiv1_021478 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(OCc5ccccc5)cc4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A07 compound treatment 708463.0 241000.0 0.5 608669.0 147000.0 0.32 0.577 0.977 1292936 ChemDiv1_021479 Cc1ccc(cc1F)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A08 compound treatment 695058.0 227000.0 0.47 638712.0 177000.0 0.38 0.6034 0.995 1345185 ChemDiv1_021480 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(Br)cc3)O)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A09 compound treatment 714516.0 247000.0 0.51 682171.0 221000.0 0.48 0.6983 0.9995 1524222 ChemDiv1_021481 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A10 compound treatment 716675.0 249000.0 0.51 627993.0 167000.0 0.36 0.6185 0.985 1665529 ChemDiv1_021482 OC1=C(C(NC1=O)c2cccc(F)c2)C(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A11 compound treatment 734523.0 267000.0 0.55 630092.0 169000.0 0.37 0.6478 0.9801 1322841 ChemDiv1_021483 CN(C)c1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A12 compound treatment 726724.0 259000.0 0.53 608837.0 147000.0 0.32 0.6039 0.9696 1980024 ChemDiv1_021484 CC(=O)C1=C(O)C(=O)N(C1c2ccc3OCOc3c2)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A13 compound treatment 735582.0 268000.0 0.55 620830.0 159000.0 0.35 0.6352 0.9743 1612087 ChemDiv1_021485 CCOc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A14 compound treatment 752971.0 285000.0 0.59 639507.0 178000.0 0.39 0.6891 0.9789 1940139 ChemDiv1_021486 CC1(C)CC(=O)C(=CNCCc2ccc(cc2)S(=O)(=O)N)C(=O)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A15 compound treatment 746748.0 279000.0 0.58 641471.0 180000.0 0.39 0.683 0.9819 1980025 ChemDiv1_021487 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A16 compound treatment 723971.0 256000.0 0.53 638158.0 177000.0 0.38 0.6447 0.9874 1980026 ChemDiv1_021488 CCOc1ccc(cc1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cc(Br)ccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A17 compound treatment 705614.0 238000.0 0.49 642171.0 181000.0 0.39 0.6241 0.9937 1980027 ChemDiv1_021489 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A18 compound treatment 743166.0 275000.0 0.57 659465.0 198000.0 0.43 0.7054 0.9903 1980028 ChemDiv1_021490 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A19 compound treatment 741704.0 274000.0 0.57 607179.0 146000.0 0.32 0.6232 0.962 1980029 ChemDiv1_021491 CCCCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(OC)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A20 compound treatment 693704.0 226000.0 0.47 593859.0 133000.0 0.29 0.5328 0.9727 1678284 ChemDiv1_021492 COc1cc2NC(SCC(=O)c2cc1OC)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A21 compound treatment 745548.0 278000.0 0.57 629545.0 168000.0 0.36 0.663 0.9759 1980030 ChemDiv1_021493 [O-][N+](=O)c1ccccc1CC(=O)N2CCCc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A22 compound treatment 702583.0 235000.0 0.48 589470.0 128000.0 0.28 0.539 0.9649 1980031 ChemDiv1_021494 [O-][N+](=O)c1cccc2C(=O)N(C3C(N(C3=O)c4ccc(F)cc4)c5cccs5)C(=O)c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A23 mock treatment 694798.0 227000.0 0.47 591627.0 130000.0 0.28 0.5309 0.9704 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 A24 mock treatment 208187.0 -259000.0 -0.54 243916.0 -217000.0 -0.47 -0.7115 -0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B01 compound treatment 682794.0 215000.0 0.44 576645.0 115000.0 0.25 0.4905 0.9629 1980032 ChemDiv1_021495 Cc1cc(ccc1Br)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B02 compound treatment 1068393.0 601000.0 1.24 925937.0 465000.0 1.01 1.5879 0.9946 1782697 ChemDiv1_021496 CCOc1ccc(cc1)C2C3CN(CC)CC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B03 compound treatment 700822.0 233000.0 0.48 646456.0 185000.0 0.4 0.6236 0.9958 1980033 ChemDiv1_021497 Cc1ccc(F)cc1N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B04 compound treatment 1083883.0 616000.0 1.27 1077567.0 616000.0 1.33 1.8426 0.9997 1980034 ChemDiv1_021498 CCN1CC=C2C(C1)C(c3ccccc3OC)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B05 compound treatment 736238.0 269000.0 0.55 677297.0 216000.0 0.47 0.7225 0.9964 1199631 ChemDiv1_021499 N#Cc1c2CCCc2c(N3CCCCCC3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B06 compound treatment 932838.0 465000.0 0.96 845253.0 384000.0 0.83 1.2666 0.9974 1286761 ChemDiv1_021500 O=C(C1C(c2ccccc2)C(C#N)(C#N)C3C=Cc4ccccc4N13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B07 compound treatment 776402.0 309000.0 0.64 703043.0 242000.0 0.52 0.8206 0.9952 1980035 ChemDiv1_021501 OCCCNc1c2CCCc2c(C#N)c3nc4ccccc4n13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B08 compound treatment 736019.0 268000.0 0.55 654518.0 193000.0 0.42 0.6874 0.9904 1440766 ChemDiv1_021502 OC1=C(C(N(C1=O)c2ccc(O)cc2)c3ccccc3F)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B09 compound treatment 756252.0 289000.0 0.6 668182.0 207000.0 0.45 0.7378 0.9901 1198393 ChemDiv1_021503 CC1CN(CC(C)O1)c2c3CCCc3c(C#N)c4nc5ccccc5n24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B10 compound treatment 730348.0 263000.0 0.54 681574.0 220000.0 0.48 0.7205 0.9979 1708848 ChemDiv1_021504 COc1cccc(c1)C2N(C(=O)C3=C2C(=NCCN3)c4ccc(Cl)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B11 compound treatment 745470.0 278000.0 0.57 701557.0 240000.0 0.52 0.7731 0.9988 1980036 ChemDiv1_021505 Cc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B12 compound treatment 713027.0 245000.0 0.51 638602.0 177000.0 0.38 0.6294 0.9906 1980037 ChemDiv1_021506 [O-][N+](=O)c1cccc(c1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B13 compound treatment 739328.0 272000.0 0.56 675298.0 214000.0 0.46 0.724 0.9955 1980038 ChemDiv1_021507 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B14 compound treatment 770261.0 303000.0 0.62 708100.0 247000.0 0.53 0.8193 0.997 1449322 ChemDiv1_021508 CN(C)c1ccc(cc1)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B15 compound treatment 748126.0 280000.0 0.58 706580.0 245000.0 0.53 0.7847 0.9991 1980039 ChemDiv1_021509 COc1ccc(cc1Cl)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B16 compound treatment 737385.0 270000.0 0.56 658286.0 197000.0 0.43 0.6951 0.9913 1980040 ChemDiv1_021510 CCCOc1ccc(NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B17 compound treatment 778594.0 311000.0 0.64 685968.0 225000.0 0.49 0.7976 0.9906 1980041 ChemDiv1_021511 O=C(CO/N=C/c1ccccc1)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B18 compound treatment 755796.0 288000.0 0.59 679740.0 218000.0 0.47 0.7548 0.9935 1155524 ChemDiv1_021512 Brc1cc2C(CC(=O)Nc2c3ccccc13)c4cccc(Oc5ccccc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B19 compound treatment 759143.0 291000.0 0.6 661473.0 200000.0 0.43 0.7318 0.987 1980042 ChemDiv1_021513 COc1ccc(cc1Cl)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B20 compound treatment 725474.0 258000.0 0.53 658498.0 197000.0 0.43 0.6781 0.994 1389574 ChemDiv1_021514 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccccc4)c5ccc6OCOc6c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B21 compound treatment 725331.0 258000.0 0.53 673121.0 212000.0 0.46 0.7002 0.9973 1980043 ChemDiv1_021515 CCCCN(CCCC)Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B22 compound treatment 736401.0 269000.0 0.55 625957.0 165000.0 0.36 0.6442 0.9771 1501029 ChemDiv1_021516 Cc1ccc2NC(=O)CC(c3ccc(Cl)cc3Cl)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B23 mock treatment 756170.0 289000.0 0.6 639025.0 178000.0 0.38 0.6931 0.9776 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 B24 mock treatment 222847.0 -245000.0 -0.51 208700.0 -253000.0 -0.55 -0.744 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C01 compound treatment 693854.0 226000.0 0.47 580199.0 119000.0 0.26 0.5121 0.9606 1947846 ChemDiv1_021517 Cc1ccc(cc1[N+](=O)[O-])C2C3=C(CC(C)(C)CC3=O)Nc4ccc5ccccc5c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C02 compound treatment 721389.0 254000.0 0.52 650040.0 189000.0 0.41 0.6591 0.9924 1980044 ChemDiv1_021518 COc1ccc(NC(=O)c2c(NC(=O)C(F)(F)F)sc3CCCc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C03 compound treatment 720017.0 252000.0 0.52 667230.0 206000.0 0.45 0.6835 0.997 1648949 ChemDiv1_021519 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cc(Cl)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C04 compound treatment 727250.0 260000.0 0.54 651052.0 190000.0 0.41 0.6693 0.9914 1471520 ChemDiv1_021520 CCOc1cccc(c1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C05 compound treatment 740413.0 273000.0 0.56 684819.0 223000.0 0.48 0.7401 0.9971 1233875 ChemDiv1_021521 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C06 compound treatment 672235.0 205000.0 0.42 631858.0 171000.0 0.37 0.5596 0.9977 1980045 ChemDiv1_021522 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cccc(OCc5c(F)cccc5Cl)c4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C07 compound treatment 707912.0 240000.0 0.5 709337.0 248000.0 0.54 0.7302 0.9992 1615211 ChemDiv1_021523 COc1ccc(N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C08 compound treatment 722594.0 255000.0 0.53 687660.0 226000.0 0.49 0.7185 0.9994 1374899 ChemDiv1_021524 OC1=C(C(N(C1=O)c2ccccn2)c3ccc(F)cc3)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C09 compound treatment 737239.0 270000.0 0.56 706849.0 246000.0 0.53 0.7692 0.9997 1353501 ChemDiv1_021525 CN(C)c1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C10 compound treatment 762303.0 295000.0 0.61 692033.0 231000.0 0.5 0.7831 0.9952 1980046 ChemDiv1_021526 COc1ccccc1C2NC(=O)C(=C2C(=O)c3ccc(Br)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C11 compound treatment 786040.0 318000.0 0.66 730399.0 269000.0 0.58 0.8765 0.9982 1496421 ChemDiv1_021527 Fc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C12 compound treatment 737633.0 270000.0 0.56 665670.0 204000.0 0.44 0.7068 0.9934 1021118 ChemDiv1_021528 OC(=O)CN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C13 compound treatment 761250.0 294000.0 0.61 734663.0 273000.0 0.59 0.8468 0.9999 1980047 ChemDiv1_021529 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C14 compound treatment 742732.0 275000.0 0.57 688508.0 227000.0 0.49 0.7492 0.9974 1160328 ChemDiv1_021530 CC1(C)CC(=O)C=C(C1)NC2CC(C)(C)NC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C15 compound treatment 770341.0 303000.0 0.62 732561.0 271000.0 0.59 0.8569 0.9995 1980048 ChemDiv1_021531 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C16 compound treatment 744262.0 277000.0 0.57 696081.0 235000.0 0.51 0.763 0.9983 1980049 ChemDiv1_021532 COc1ccc(Br)cc1C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C17 compound treatment 760411.0 293000.0 0.6 718843.0 258000.0 0.56 0.8214 0.9992 1980050 ChemDiv1_021533 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C18 compound treatment 742372.0 275000.0 0.57 676818.0 215000.0 0.47 0.7308 0.9953 1980051 ChemDiv1_021534 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C19 compound treatment 765787.0 298000.0 0.62 677264.0 216000.0 0.47 0.7656 0.9908 1195879 ChemDiv1_021535 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C20 compound treatment 709285.0 242000.0 0.5 680305.0 219000.0 0.47 0.6878 0.9997 1184921 ChemDiv1_021536 Clc1ccc(cc1)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C21 compound treatment 731627.0 264000.0 0.54 680042.0 219000.0 0.47 0.72 0.9975 1980052 ChemDiv1_021537 CCCC1C(=C(NC(=C1C(=O)C)C)SCc2cccc(c2)[N+](=O)[O-])C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C22 compound treatment 730674.0 263000.0 0.54 651158.0 190000.0 0.41 0.6744 0.9905 1980053 ChemDiv1_021538 Cc1c(Cl)cccc1N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C23 mock treatment 712996.0 245000.0 0.51 686442.0 225000.0 0.49 0.7026 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 C24 mock treatment 223800.0 -244000.0 -0.5 216533.0 -245000.0 -0.53 -0.7306 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D01 compound treatment 688401.0 221000.0 0.46 582331.0 121000.0 0.26 0.5074 0.9654 1980054 ChemDiv1_021539 Cc1ccc(cc1F)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D02 compound treatment 810089.0 342000.0 0.71 774515.0 313000.0 0.68 0.9791 0.9998 1980055 ChemDiv1_021540 NC1=C(C#N)C2=CCN(Cc3ccccc3)CC2C(c4cccc(Br)c4)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D03 compound treatment 691597.0 224000.0 0.46 644673.0 183000.0 0.4 0.6074 0.9971 1980056 ChemDiv1_021541 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D04 compound treatment 783875.0 316000.0 0.65 849389.0 388000.0 0.84 1.0555 0.9922 1980057 ChemDiv1_021542 COc1cc(ccc1OC(C)C)[C@@H]2[C@H]3CN(C)CC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D05 compound treatment 719325.0 252000.0 0.52 673225.0 212000.0 0.46 0.6916 0.9981 1980058 ChemDiv1_021543 N#Cc1c2CCCc2c(N3CCN(CC3)C(c4ccccc4)c5ccccc5)n6c7ccccc7nc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D06 compound treatment 930168.0 462000.0 0.95 851218.0 390000.0 0.84 1.2718 0.9981 1980059 ChemDiv1_021544 NC1=C(C#N)C(C#N)(C#N)[C@H]([C@@H]2CCCC=C21)c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D07 compound treatment 723781.0 256000.0 0.53 687448.0 226000.0 0.49 0.7199 0.9993 1600221 ChemDiv1_021545 CCc1c(C)c(C#N)c2nc3ccccc3n2c1N4CCN(Cc5ccccc5)CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D08 compound treatment 720356.0 253000.0 0.52 650675.0 189000.0 0.41 0.6586 0.9929 1980060 ChemDiv1_021546 COc1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(Cl)cc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D09 compound treatment 718115.0 250000.0 0.52 696157.0 235000.0 0.51 0.7249 1.0 1206496 ChemDiv1_021547 O=S(=O)(N1CCN(CC1)C2c3ccccc3-c4ccccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D10 compound treatment 736446.0 269000.0 0.55 688081.0 227000.0 0.49 0.7393 0.9981 1980061 ChemDiv1_021548 [O-][N+](=O)c1cccc(c1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D11 compound treatment 731151.0 263000.0 0.54 683645.0 222000.0 0.48 0.7248 0.9981 1980062 ChemDiv1_021549 [O-][N+](=O)c1ccc2C(=O)N(C3C(N(C3=O)c4ccc(Cl)c(Cl)c4)c5ccc(F)cc5)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D12 compound treatment 728079.0 260000.0 0.54 653526.0 192000.0 0.42 0.6742 0.992 1727295 ChemDiv1_021550 COc1cccc(c1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D13 compound treatment 707517.0 240000.0 0.5 686300.0 225000.0 0.49 0.6944 1.0 1980063 ChemDiv1_021551 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D14 compound treatment 708609.0 241000.0 0.5 640692.0 179000.0 0.39 0.6262 0.9925 1484035 ChemDiv1_021552 Oc1ccc(Br)cc1C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D15 compound treatment 746033.0 278000.0 0.57 702634.0 241000.0 0.52 0.7756 0.9989 1980064 ChemDiv1_021553 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D16 compound treatment 800335.0 333000.0 0.69 691929.0 231000.0 0.5 0.8385 0.9877 1980065 ChemDiv1_021554 CCCCOc1ccc(NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D17 compound treatment 775909.0 308000.0 0.64 723558.0 262000.0 0.57 0.8512 0.9984 1980066 ChemDiv1_021555 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D18 compound treatment 722405.0 255000.0 0.53 671548.0 210000.0 0.45 0.6935 0.9974 1941084 ChemDiv1_021556 COc1cccc(C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D19 compound treatment 739159.0 271000.0 0.56 704475.0 243000.0 0.53 0.7684 0.9995 1980067 ChemDiv1_021557 Cc1cccc(c1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D20 compound treatment 717309.0 250000.0 0.52 668450.0 207000.0 0.45 0.6814 0.9976 1651871 ChemDiv1_021558 O=c1c(=Cc2ccc3OCOc3c2)sc4nc5cccnc5n14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D21 compound treatment 734132.0 266000.0 0.55 694699.0 233000.0 0.51 0.7461 0.9991 1736707 ChemDiv1_021559 CC1CCCCN1Cc2c(O)ccc3c4CCCc4c(=O)oc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D22 compound treatment 743819.0 276000.0 0.57 677093.0 216000.0 0.47 0.7333 0.9951 1238688 ChemDiv1_021560 CC1=C(C(CC(=O)N1)c2ccc(Cl)cc2Cl)C(=O)OCCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D23 mock treatment 710811.0 243000.0 0.5 674445.0 213000.0 0.46 0.6811 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 D24 mock treatment 218166.0 -250000.0 -0.52 191149.0 -270000.0 -0.58 -0.7777 -0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E01 compound treatment 709077.0 241000.0 0.5 602265.0 141000.0 0.31 0.5681 0.9722 1670263 ChemDiv1_021561 CSc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4ccc5ccccc5c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E02 compound treatment 682698.0 215000.0 0.44 622713.0 161000.0 0.35 0.5608 0.993 1323296 ChemDiv1_021562 COc1ccc(CCN(C(=O)c2ccc(F)cc2)C3=CC4CCC(C3)N4C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E03 compound treatment 704907.0 237000.0 0.49 668343.0 207000.0 0.45 0.6631 0.999 1595839 ChemDiv1_021563 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E04 compound treatment 690909.0 223000.0 0.46 660562.0 199000.0 0.43 0.6308 0.9994 1947482 ChemDiv1_021564 Fc1ccc(cc1F)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E05 compound treatment 709426.0 242000.0 0.5 683761.0 222000.0 0.48 0.6933 0.9998 1159860 ChemDiv1_021565 Cc1ccc(Cl)cc1N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E06 compound treatment 682741.0 215000.0 0.44 673540.0 212000.0 0.46 0.6387 0.9999 1980068 ChemDiv1_021566 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(Cc5ccccc5F)c6ccccc46)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E07 compound treatment 728854.0 261000.0 0.54 687983.0 227000.0 0.49 0.7281 0.9989 1610765 ChemDiv1_021567 CCOc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E08 compound treatment 736305.0 269000.0 0.55 704496.0 243000.0 0.53 0.7643 0.9997 1781840 ChemDiv1_021568 OC1=C(C(N(C1=O)c2ccccn2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E09 compound treatment 744100.0 276000.0 0.57 705804.0 244000.0 0.53 0.7776 0.9993 1740430 ChemDiv1_021569 Cc1ccc(cc1C)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E10 compound treatment 751417.0 284000.0 0.59 691547.0 230000.0 0.5 0.7665 0.9968 1980069 ChemDiv1_021570 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E11 compound treatment 679913.0 212000.0 0.44 721999.0 261000.0 0.56 0.7087 0.9922 1512835 ChemDiv1_021571 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E12 compound treatment 753365.0 286000.0 0.59 722892.0 262000.0 0.57 0.8173 0.9998 1741455 ChemDiv1_021572 COc1ccccc1NC(=O)CN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E13 compound treatment 711350.0 244000.0 0.5 713998.0 253000.0 0.55 0.7424 0.9991 1203262 ChemDiv1_021573 CCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cc(Cl)cc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E14 compound treatment 724982.0 257000.0 0.53 706415.0 245000.0 0.53 0.7507 1.0 1198520 ChemDiv1_021574 Cc1cccc2c1N(C(=O)Cc3ccccc3)C(C)(C)CC2(C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E15 compound treatment 707502.0 240000.0 0.5 739091.0 278000.0 0.6 0.7752 0.9954 1980070 ChemDiv1_021575 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E16 compound treatment 733518.0 266000.0 0.55 702896.0 242000.0 0.52 0.7577 0.9997 1980071 ChemDiv1_021576 COc1ccc(Br)cc1C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E17 compound treatment 774178.0 307000.0 0.63 722237.0 261000.0 0.56 0.8467 0.9984 1980072 ChemDiv1_021577 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E18 compound treatment 752431.0 285000.0 0.59 685754.0 224000.0 0.49 0.7591 0.9955 1980073 ChemDiv1_021578 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E19 compound treatment 728651.0 261000.0 0.54 696222.0 235000.0 0.51 0.7404 0.9996 1980074 ChemDiv1_021579 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(Cl)cc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E20 compound treatment 733630.0 266000.0 0.55 703279.0 242000.0 0.52 0.7585 0.9997 1159017 ChemDiv1_021580 CC(C)c1ccc(cc1)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E21 compound treatment 765472.0 298000.0 0.61 713380.0 252000.0 0.55 0.8204 0.9982 1980075 ChemDiv1_021581 CC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)C)c2sccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E22 compound treatment 720393.0 253000.0 0.52 656580.0 195000.0 0.42 0.6677 0.9945 1980076 ChemDiv1_021582 Cc1ccc(Cl)cc1N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E23 mock treatment 734417.0 267000.0 0.55 692630.0 231000.0 0.5 0.7433 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 E24 mock treatment 212595.0 -255000.0 -0.53 256231.0 -205000.0 -0.44 -0.6862 -0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F01 compound treatment 683041.0 215000.0 0.44 721287.0 260000.0 0.56 0.7122 0.9932 1980077 ChemDiv1_021583 COc1cccc(c1)N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F02 compound treatment 1206394.0 739000.0 1.52 1110959.0 650000.0 1.41 2.0725 0.9992 1522711 ChemDiv1_021584 CCCN1CC=C2C(C1)C(c3cccc(OC)c3OC)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F03 compound treatment 639562.0 172000.0 0.35 667091.0 206000.0 0.45 0.5658 0.9937 1980078 ChemDiv1_021585 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F04 compound treatment 774938.0 307000.0 0.63 838336.0 377000.0 0.82 1.0255 0.9922 1980079 ChemDiv1_021586 COc1cc(OC)cc(c1)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F05 compound treatment 687497.0 220000.0 0.45 679027.0 218000.0 0.47 0.654 0.9998 1348868 ChemDiv1_021587 N#Cc1c2CCCc2c(N3CCN(CC3)c4ccccn4)n5c6ccccc6nc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F06 compound treatment 686226.0 219000.0 0.45 641501.0 180000.0 0.39 0.5948 0.9974 1980080 ChemDiv1_021588 COc1ccc(OC)c(c1)C2NC(=S)NC(=C2C(=O)Nc3cccc(Cl)c3C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F07 compound treatment 1046824.0 579000.0 1.2 678607.0 217000.0 0.47 1.1779 0.9169 1401341 ChemDiv1_021589 CCc1c(C)c(C#N)c2nc3ccccc3n2c1Nc4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F08 compound treatment 720690.0 253000.0 0.52 685189.0 224000.0 0.48 0.7119 0.9993 1646087 ChemDiv1_021590 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3)c4cccc(c4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F09 compound treatment 727843.0 260000.0 0.54 694593.0 233000.0 0.5 0.7368 0.9995 1553937 ChemDiv1_021591 CC1(C)Cc2ccccc2-c3nc(NCCO)n(Cc4ccccc4)c(=O)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F10 compound treatment 714161.0 246000.0 0.51 679630.0 218000.0 0.47 0.6939 0.9993 1372939 ChemDiv1_021592 Fc1ccc(cc1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F11 compound treatment 769200.0 302000.0 0.62 637585.0 176000.0 0.38 0.7099 0.9724 1980081 ChemDiv1_021593 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F12 compound treatment 628594.0 161000.0 0.33 669020.0 208000.0 0.45 0.5527 0.9889 1980082 ChemDiv1_021594 [O-][N+](=O)c1ccc(cc1N2CCCCC2)N3CCN(CC3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F13 compound treatment 776966.0 309000.0 0.64 685841.0 225000.0 0.49 0.7951 0.9909 1980083 ChemDiv1_021595 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(OC)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F14 compound treatment 740646.0 273000.0 0.56 668728.0 207000.0 0.45 0.7159 0.9937 1655012 ChemDiv1_021596 COc1ccc(Br)cc1C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F15 compound treatment 734741.0 267000.0 0.55 691959.0 231000.0 0.5 0.7428 0.9988 1980084 ChemDiv1_021597 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F16 compound treatment 733078.0 265000.0 0.55 677479.0 216000.0 0.47 0.7182 0.9969 1980085 ChemDiv1_021598 CCCCCOc1ccc(NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F17 compound treatment 801944.0 334000.0 0.69 724156.0 263000.0 0.57 0.8902 0.9954 1669225 ChemDiv1_021599 Clc1ccc(cc1Cl)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F18 compound treatment 730017.0 262000.0 0.54 678941.0 218000.0 0.47 0.716 0.9976 1328195 ChemDiv1_021600 Cc1cc2nc3c4cccc5cccc(c(=O)n3c2cc1C)c54 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F19 compound treatment 735278.0 268000.0 0.55 680574.0 219000.0 0.47 0.7262 0.9971 1980086 ChemDiv1_021601 Cc1ccc(cc1C)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F20 compound treatment 746789.0 279000.0 0.58 687959.0 227000.0 0.49 0.7543 0.9968 1580347 ChemDiv1_021602 CCOC(=O)Cc1nnc2c(Nc3cccc(Br)c3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F21 compound treatment 755701.0 288000.0 0.59 716202.0 255000.0 0.55 0.8105 0.9993 1278013 ChemDiv1_021603 CC1CCCC(C)N1Cc2c(O)ccc3c4CCCc4c(=O)oc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F22 compound treatment 721535.0 254000.0 0.52 659871.0 199000.0 0.43 0.6744 0.9951 1210447 ChemDiv1_021604 COc1cccc(C2CC(=O)Nc3c2cc(Br)c4ccccc34)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F23 mock treatment 732783.0 265000.0 0.55 676846.0 216000.0 0.47 0.7168 0.9968 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 F24 mock treatment 202417.0 -265000.0 -0.55 215025.0 -246000.0 -0.53 -0.7642 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G01 compound treatment 672643.0 205000.0 0.42 606358.0 145000.0 0.31 0.5211 0.9892 1980087 ChemDiv1_021605 CC1(C)CC(=O)C2=C(C1)Nc3ccc4ccccc4c3C2c5ccc(cc5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G02 compound treatment 702241.0 235000.0 0.48 642214.0 181000.0 0.39 0.6192 0.9944 1230293 ChemDiv1_021606 COc1ccc(CCN(C(=O)c2cc(Cl)cc(Cl)c2)C3=CC4CCC(C3)N4C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G03 compound treatment 722448.0 255000.0 0.53 661060.0 200000.0 0.43 0.6776 0.9953 1265433 ChemDiv1_021607 CCOc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cc(OC)c(OC)c(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G04 compound treatment 674175.0 207000.0 0.43 668547.0 207000.0 0.45 0.6186 0.9997 1980088 ChemDiv1_021608 Cc1cc(cc([N+](=O)[O-])c1C)c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G05 compound treatment 744754.0 277000.0 0.57 684722.0 223000.0 0.48 0.7463 0.9965 1566524 ChemDiv1_021609 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G06 compound treatment 681599.0 214000.0 0.44 656156.0 195000.0 0.42 0.6104 0.9997 1980089 ChemDiv1_021610 COc1ccc(OC)c(c1)C2NC(=S)NC(=C2C(=O)Nc3ccccc3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G07 compound treatment 719068.0 251000.0 0.52 705739.0 244000.0 0.53 0.741 1.0 1533775 ChemDiv1_021611 CCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G08 compound treatment 698176.0 231000.0 0.48 651264.0 190000.0 0.41 0.6271 0.9973 1980090 ChemDiv1_021612 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(Br)cc3)O)c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G09 compound treatment 739884.0 272000.0 0.56 688248.0 227000.0 0.49 0.7446 0.9977 1446297 ChemDiv1_021613 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G10 compound treatment 756904.0 289000.0 0.6 677080.0 216000.0 0.47 0.7524 0.9926 1980091 ChemDiv1_021614 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G11 compound treatment 746211.0 279000.0 0.57 724417.0 263000.0 0.57 0.8092 1.0 1198330 ChemDiv1_021615 COc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G12 compound treatment 691632.0 224000.0 0.46 705820.0 244000.0 0.53 0.7011 0.9977 1980092 ChemDiv1_021616 OC(=O)c1cc(cc(c1)C(=O)O)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G13 compound treatment 739113.0 271000.0 0.56 727392.0 266000.0 0.58 0.8034 0.9999 1545919 ChemDiv1_021617 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G14 compound treatment 704270.0 237000.0 0.49 715501.0 254000.0 0.55 0.7343 0.9982 1135599 ChemDiv1_021618 Cc1ccc2NC(=O)CC(c3ccccc3Br)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G15 compound treatment 767682.0 300000.0 0.62 775217.0 314000.0 0.68 0.9183 0.9989 1980093 ChemDiv1_021619 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(OCC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G16 compound treatment 733546.0 266000.0 0.55 638636.0 177000.0 0.38 0.6594 0.9847 1980094 ChemDiv1_021620 COc1ccc(Br)cc1C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G17 compound treatment 731389.0 264000.0 0.54 728771.0 267000.0 0.58 0.7942 0.9995 1980095 ChemDiv1_021621 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Cl)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G18 compound treatment 727513.0 260000.0 0.54 664103.0 203000.0 0.44 0.6896 0.995 1980096 ChemDiv1_021622 [O-][N+](=O)c1ccc2C(=O)N(C3C(N(C3=O)c4cccc(c4)C(F)(F)F)c5cccs5)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G19 compound treatment 731485.0 264000.0 0.54 675832.0 214000.0 0.46 0.7134 0.9968 1980097 ChemDiv1_021623 CCCCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G20 compound treatment 809126.0 341000.0 0.7 710973.0 250000.0 0.54 0.8805 0.9914 1980098 ChemDiv1_021624 CCCCCCCCOc1ccc(cc1)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G21 compound treatment 738632.0 271000.0 0.56 702046.0 241000.0 0.52 0.7639 0.9994 1670299 ChemDiv1_021625 Clc1cccc(C2CC(=O)Nc3c2cc(Br)c4ccccc34)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G22 compound treatment 717821.0 250000.0 0.52 690325.0 229000.0 0.5 0.7156 0.9998 1980099 ChemDiv1_021626 Cc1ccc(cc1Cl)N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G23 mock treatment 735458.0 268000.0 0.55 714553.0 253000.0 0.55 0.7784 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 G24 mock treatment 233298.0 -234000.0 -0.48 247854.0 -213000.0 -0.46 -0.6688 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H01 compound treatment 659654.0 192000.0 0.4 556085.0 94700.0 0.21 0.4252 0.953 1980100 ChemDiv1_021627 [O-][N+](=O)c1ccc2C(=O)N(C3C(N(C3=O)c4ccc(Cl)cc4[N+](=O)[O-])c5cccs5)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H02 compound treatment 1180583.0 713000.0 1.47 1184655.0 723000.0 1.57 2.1476 0.9995 1980101 ChemDiv1_021628 COc1cccc(C2C3CN(CC=C3C(=C(N)C2(C#N)C#N)C#N)C(C)C)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H03 compound treatment 689260.0 222000.0 0.46 644569.0 183000.0 0.4 0.6039 0.9975 1980102 ChemDiv1_021629 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H04 compound treatment 802612.0 335000.0 0.69 686564.0 225000.0 0.49 0.8336 0.9854 1980103 ChemDiv1_021630 CCOC(=O)N1CC=C2C(C1)C(c3ccccc3C(F)(F)F)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H05 compound treatment 708811.0 241000.0 0.5 652090.0 191000.0 0.41 0.6439 0.9957 1315619 ChemDiv1_021631 CN1CCN(CC1)c2c3CCCc3c(C#N)c4nc5ccccc5n24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H06 compound treatment 663633.0 196000.0 0.4 675143.0 214000.0 0.46 0.6133 0.9978 1928157 ChemDiv1_021632 COc1ccc(OC)c(c1)C2NC(=S)NC(=C2C(=O)Nc3cc(Cl)ccc3OC)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H07 compound treatment 716228.0 249000.0 0.51 683075.0 222000.0 0.48 0.7022 0.9994 1735378 ChemDiv1_021633 CCN(CC)c1ccc(Nc2c(CC)c(C)c(C#N)c3nc4ccccc4n23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H08 compound treatment 730901.0 263000.0 0.54 665128.0 204000.0 0.44 0.6961 0.9946 1319744 ChemDiv1_021634 COc1ccc(cc1OC)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H09 compound treatment 700335.0 233000.0 0.48 634909.0 174000.0 0.38 0.6053 0.9926 1679568 ChemDiv1_021635 CCOC(=O)C1=C(NC(=S)NC(=O)c2ccccc2)c3ccccc3CC1(CC)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H10 compound treatment 707020.0 239000.0 0.49 658965.0 198000.0 0.43 0.6518 0.9974 1285510 ChemDiv1_021636 Fc1cccc(c1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H11 compound treatment 694004.0 226000.0 0.47 697253.0 236000.0 0.51 0.6914 0.999 1980104 ChemDiv1_021637 COc1ccc(cc1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H12 compound treatment 679276.0 212000.0 0.44 640964.0 180000.0 0.39 0.5838 0.9983 1191653 ChemDiv1_021638 Oc1ccccc1C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H13 compound treatment 745094.0 277000.0 0.57 673319.0 212000.0 0.46 0.7294 0.994 1980105 ChemDiv1_021639 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(Cl)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H14 compound treatment 672765.0 205000.0 0.42 641953.0 181000.0 0.39 0.5758 0.9992 1266691 ChemDiv1_021640 Cc1cccc(C2NC(=O)c3c4CCCCc4sc3N2)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H15 compound treatment 766559.0 299000.0 0.62 733328.0 272000.0 0.59 0.8526 0.9997 1426955 ChemDiv1_021641 CC(C)c1ccc(C)cc1OCC(=O)Nc2sc3CCCCCc3c2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H16 compound treatment 720119.0 252000.0 0.52 666635.0 205000.0 0.44 0.6827 0.9969 1980106 ChemDiv1_021642 CC(C)CCOc1ccc(NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H17 compound treatment 722156.0 254000.0 0.53 658970.0 198000.0 0.43 0.6739 0.9948 1980107 ChemDiv1_021643 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H18 compound treatment 715400.0 248000.0 0.51 674736.0 213000.0 0.46 0.6882 0.9987 1658483 ChemDiv1_021644 CCc1c(C)c(C#N)c2nc3ccccc3n2c1N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H19 compound treatment 726347.0 259000.0 0.53 683912.0 223000.0 0.48 0.7182 0.9987 1980108 ChemDiv1_021645 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5cccc(Cl)c5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H20 compound treatment 681511.0 214000.0 0.44 650697.0 189000.0 0.41 0.6019 0.9993 1709675 ChemDiv1_021646 CCOC(=O)Cc1nnc2c(Nc3ccc(OC)cc3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H21 compound treatment 754295.0 287000.0 0.59 665596.0 204000.0 0.44 0.731 0.9897 1410809 ChemDiv1_021647 CCCCN(C)Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H22 compound treatment 737059.0 269000.0 0.56 668191.0 207000.0 0.45 0.7098 0.9942 1660555 ChemDiv1_021648 Fc1ccc(Br)cc1C2CC(=O)Nc3c2ccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H23 mock treatment 708338.0 241000.0 0.5 674528.0 213000.0 0.46 0.6776 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 H24 mock treatment 219077.0 -249000.0 -0.51 205820.0 -256000.0 -0.55 -0.7539 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I01 compound treatment 685661.0 218000.0 0.45 602557.0 141000.0 0.31 0.5343 0.9822 1324923 ChemDiv1_021649 CC1(C)CC(=O)C2=C(C1)Nc3ccc4ccccc4c3C2c5ccc(F)c(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I02 compound treatment 642737.0 175000.0 0.36 649808.0 188000.0 0.41 0.544 0.9982 1980109 ChemDiv1_021650 COc1cc(cc(OC)c1OC)C(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I03 compound treatment 686348.0 219000.0 0.45 665468.0 204000.0 0.44 0.6316 0.9999 1212870 ChemDiv1_021651 COc1ccc(cc1Cl)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cc(OC)c(OC)c(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I04 compound treatment 657936.0 190000.0 0.39 662489.0 201000.0 0.44 0.5856 0.9987 1980110 ChemDiv1_021652 Cc1ccc(cc1[N+](=O)[O-])c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I05 compound treatment 701679.0 234000.0 0.48 692322.0 231000.0 0.5 0.6951 0.9999 1980111 ChemDiv1_021653 Fc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I06 compound treatment 680795.0 213000.0 0.44 618011.0 157000.0 0.34 0.5509 0.9917 1980112 ChemDiv1_021654 COc1ccccc1C2NC(=S)NC(=C2C(=O)Nc3ccccc3C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I07 compound treatment 702475.0 235000.0 0.48 671795.0 210000.0 0.46 0.6648 0.9995 1559158 ChemDiv1_021655 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I08 compound treatment 705088.0 237000.0 0.49 682935.0 222000.0 0.48 0.6857 0.9999 1980113 ChemDiv1_021656 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccc(Cl)cc3)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I09 compound treatment 717875.0 250000.0 0.52 713623.0 252000.0 0.55 0.7513 0.9996 1980114 ChemDiv1_021657 COc1ccc(N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cc(OC)c(OC)c(OC)c5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I10 compound treatment 724020.0 256000.0 0.53 701587.0 240000.0 0.52 0.7419 1.0 1195714 ChemDiv1_021658 OCCN1C(C(=C(O)C1=O)C(=O)c2ccc(Br)cc2)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I11 compound treatment 723537.0 256000.0 0.53 717896.0 257000.0 0.56 0.7661 0.9997 1980115 ChemDiv1_021659 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I12 compound treatment 706797.0 239000.0 0.49 685442.0 224000.0 0.49 0.692 1.0 1980116 ChemDiv1_021660 O=C1C2C(C3c4ccccc4C2c5ccccc35)C(=O)N1CNc6ccc7c(c6)oc8ccccc87 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I13 compound treatment 706585.0 239000.0 0.49 669688.0 208000.0 0.45 0.6676 0.999 1450529 ChemDiv1_021661 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I14 compound treatment 728369.0 261000.0 0.54 707196.0 246000.0 0.53 0.7568 1.0 1947221 ChemDiv1_021662 FC(F)(F)c1ccccc1C2CC(=O)Nc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I15 compound treatment 730619.0 263000.0 0.54 721077.0 260000.0 0.56 0.7813 0.9998 1980117 ChemDiv1_021663 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I16 compound treatment 705651.0 238000.0 0.49 708578.0 247000.0 0.54 0.7258 0.9991 1980118 ChemDiv1_021664 COc1ccc(cc1Cl)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cc(Br)ccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I17 compound treatment 732955.0 265000.0 0.55 738288.0 277000.0 0.6 0.8111 0.999 1980119 ChemDiv1_021665 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(Cl)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I18 compound treatment 711560.0 244000.0 0.5 703146.0 242000.0 0.52 0.7261 0.9998 1980120 ChemDiv1_021666 [O-][N+](=O)c1cccc2C(=O)N(C3C(N(C3=O)c4cccc(c4)C(F)(F)F)c5cccs5)C(=O)c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I19 compound treatment 732350.0 265000.0 0.55 718607.0 257000.0 0.56 0.7801 1.0 1980121 ChemDiv1_021667 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cccc(Cl)c5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I20 compound treatment 711340.0 244000.0 0.5 702583.0 241000.0 0.52 0.7249 0.9998 1132677 ChemDiv1_021668 Fc1ccc(cc1F)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I21 compound treatment 754626.0 287000.0 0.59 729614.0 268000.0 0.58 0.8294 1.0 1947681 ChemDiv1_021669 Cc1ccc2NC(=O)CC(c3ccccc3C(F)(F)F)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I22 compound treatment 712259.0 245000.0 0.5 687919.0 227000.0 0.49 0.7038 0.9999 1980122 ChemDiv1_021670 COc1ccc(cc1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cc(Br)ccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I23 mock treatment 736372.0 269000.0 0.55 714336.0 253000.0 0.55 0.7794 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 I24 mock treatment 214910.0 -253000.0 -0.52 237193.0 -224000.0 -0.49 -0.712 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J01 compound treatment 680094.0 212000.0 0.44 592200.0 131000.0 0.28 0.5103 0.9776 1980123 ChemDiv1_021671 Cc1cc(Cl)ccc1N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J02 compound treatment 916659.0 449000.0 0.93 782668.0 321000.0 0.7 1.1472 0.99 1334011 ChemDiv1_021672 CCOC(=O)N1CC=C2C(C1)C(c3ccc(cc3)c4ccccc4)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J03 compound treatment 648680.0 181000.0 0.37 653968.0 193000.0 0.42 0.559 0.9985 1980124 ChemDiv1_021673 Cc1ccc(cc1F)N2C(C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J04 compound treatment 689467.0 222000.0 0.46 651971.0 191000.0 0.41 0.6155 0.9987 1367527 ChemDiv1_021674 NC1=C(C#N)C(c2ccc(F)cc2)c3c(O1)c4OC(=C(C#N)C(c5ccc(F)cc5)c4c6ccccc36)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J05 compound treatment 733869.0 266000.0 0.55 660340.0 199000.0 0.43 0.6931 0.9927 1776034 ChemDiv1_021675 N#Cc1c2CCCc2c(N3CCN(Cc4ccccc4)CC3)n5c6ccccc6nc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J06 compound treatment 723955.0 256000.0 0.53 661654.0 200000.0 0.43 0.6807 0.9951 1980125 ChemDiv1_021676 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J07 compound treatment 723662.0 256000.0 0.53 690034.0 229000.0 0.49 0.7237 0.9995 1741799 ChemDiv1_021677 Cc1c(Cc2ccccc2)c(NC3CCCCC3)n4c5ccccc5nc4c1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J08 compound treatment 706569.0 239000.0 0.49 661386.0 200000.0 0.43 0.6549 0.9979 1929141 ChemDiv1_021678 [O-][N+](=O)c1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J09 compound treatment 708785.0 241000.0 0.5 680881.0 220000.0 0.48 0.688 0.9997 1980126 ChemDiv1_021679 C=CCSc1nnc2n(c3ccccc3)c(=O)c4c5CCCCc5sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J10 compound treatment 708520.0 241000.0 0.5 672802.0 211000.0 0.46 0.6752 0.9991 1482727 ChemDiv1_021680 COc1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccc(C)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J11 compound treatment 709019.0 241000.0 0.5 670395.0 209000.0 0.45 0.6722 0.9988 1980127 ChemDiv1_021681 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J12 compound treatment 835397.0 368000.0 0.76 809315.0 348000.0 0.75 1.0693 1.0 1624956 ChemDiv1_021682 Oc1ccc(C2NC(=O)c3c4CCCCc4sc3N2)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J13 compound treatment 706079.0 238000.0 0.49 677260.0 216000.0 0.47 0.6785 0.9997 1980128 ChemDiv1_021683 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J14 compound treatment 749328.0 282000.0 0.58 696865.0 236000.0 0.51 0.7716 0.9979 1378126 ChemDiv1_021684 COc1cccc(c1)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J15 compound treatment 754336.0 287000.0 0.59 705392.0 244000.0 0.53 0.792 0.9984 1270460 ChemDiv1_021685 CCCc1ccc(OCC(=O)Nc2sc3CCCCCc3c2C#N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J16 compound treatment 746201.0 279000.0 0.57 671295.0 210000.0 0.45 0.7279 0.9932 1980129 ChemDiv1_021686 CCOc1ccc(NC(=O)C2OC3OC4(CCCCC4)OC3C5OC6(CCCCC6)OC52)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J17 compound treatment 731844.0 264000.0 0.55 695174.0 234000.0 0.51 0.7435 0.9993 1980130 ChemDiv1_021687 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J18 compound treatment 710000.0 242000.0 0.5 659641.0 198000.0 0.43 0.6572 0.9971 1980131 ChemDiv1_021688 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(O)c(c4)[N+](=O)[O-])ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J19 compound treatment 774502.0 307000.0 0.63 689201.0 228000.0 0.49 0.7966 0.9923 1980132 ChemDiv1_021689 COc1ccc(cc1Br)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(Cl)cc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J20 compound treatment 737380.0 270000.0 0.56 680291.0 219000.0 0.47 0.7288 0.9968 1540451 ChemDiv1_021690 Cc1nnc2c(Nc3ccc(Cl)cc3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J21 compound treatment 763566.0 296000.0 0.61 698995.0 238000.0 0.51 0.7956 0.9963 1648537 ChemDiv1_021691 CCN(Cc1c(O)ccc2c3CCCc3c(=O)oc12)C4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J22 compound treatment 713253.0 246000.0 0.51 665495.0 204000.0 0.44 0.6709 0.9977 1124460 ChemDiv1_021692 COc1ccc(OC)c(c1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J23 mock treatment 810899.0 343000.0 0.71 694074.0 233000.0 0.5 0.8572 0.986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 J24 mock treatment 197904.0 -270000.0 -0.56 214501.0 -247000.0 -0.53 -0.7715 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K01 compound treatment 674269.0 207000.0 0.43 602509.0 141000.0 0.31 0.5176 0.9866 1980133 ChemDiv1_021693 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K02 compound treatment 661916.0 194000.0 0.4 613708.0 152000.0 0.33 0.5167 0.9953 1947206 ChemDiv1_021694 Fc1ccc(cc1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K03 compound treatment 697959.0 230000.0 0.48 693182.0 232000.0 0.5 0.691 0.9996 1197400 ChemDiv1_021695 Cc1cc(Cl)ccc1N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K04 compound treatment 685130.0 217000.0 0.45 672315.0 211000.0 0.46 0.6403 1.0 1200993 ChemDiv1_021696 CCc1ccc(cc1)N2N=C(C)C(Cc3cc(Cl)c(OCC=C)c(OC)c3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K05 compound treatment 704723.0 237000.0 0.49 698515.0 237000.0 0.51 0.709 0.9997 1199448 ChemDiv1_021697 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K06 compound treatment 703807.0 236000.0 0.49 598923.0 138000.0 0.3 0.5553 0.972 1014055 ChemDiv1_021698 Oc1nnc(c2ccccc2)c(n1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K07 compound treatment 704311.0 237000.0 0.49 701291.0 240000.0 0.52 0.7127 0.9995 1698003 ChemDiv1_021699 CCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K08 compound treatment 664780.0 197000.0 0.41 676694.0 215000.0 0.47 0.6173 0.9977 1980134 ChemDiv1_021700 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(Br)cc3)O)c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K09 compound treatment 711996.0 244000.0 0.5 711859.0 251000.0 0.54 0.74 0.9993 1687468 ChemDiv1_021701 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K10 compound treatment 712953.0 245000.0 0.51 694359.0 233000.0 0.5 0.7147 1.0 1598071 ChemDiv1_021702 CCOC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K11 compound treatment 735632.0 268000.0 0.55 719335.0 258000.0 0.56 0.786 1.0 1398382 ChemDiv1_021703 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cc(C)cc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K12 compound treatment 686394.0 219000.0 0.45 659406.0 198000.0 0.43 0.6224 0.9997 1980135 ChemDiv1_021704 FC(F)(F)C(=O)N(CN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)c6ccc(Cl)c(Cl)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K13 compound treatment 696096.0 228000.0 0.47 673295.0 212000.0 0.46 0.6578 0.9999 1403833 ChemDiv1_021705 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K14 compound treatment 715353.0 248000.0 0.51 651505.0 190000.0 0.41 0.6526 0.9942 1445566 ChemDiv1_021706 CC1(CN2CC3(C)CN(C1)C2c4ccc(O)c(O)c4)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K15 compound treatment 686539.0 219000.0 0.45 678102.0 217000.0 0.47 0.6512 0.9998 1980136 ChemDiv1_021707 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K16 compound treatment 693226.0 226000.0 0.47 694773.0 233000.0 0.51 0.6865 0.9992 1980137 ChemDiv1_021708 COc1ccc(Br)cc1C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K17 compound treatment 693506.0 226000.0 0.47 729101.0 268000.0 0.58 0.7394 0.9942 1980138 ChemDiv1_021709 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K18 compound treatment 711387.0 244000.0 0.5 683703.0 222000.0 0.48 0.6961 0.9998 1454330 ChemDiv1_021710 COc1cccc(c1)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K19 compound treatment 720813.0 253000.0 0.52 695183.0 234000.0 0.51 0.7274 0.9999 1980139 ChemDiv1_021711 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(F)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K20 compound treatment 716581.0 249000.0 0.51 717000.0 256000.0 0.55 0.7546 0.9993 1490704 ChemDiv1_021712 Cc1ccc(cc1)C2Nc3cccc4cccc(C(=O)CS2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K21 compound treatment 716611.0 249000.0 0.51 710413.0 249000.0 0.54 0.7446 0.9997 1366374 ChemDiv1_021713 COc1cc(Br)c(cc1OC)C2CC(=O)Nc3ccc4ccccc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K22 compound treatment 696312.0 229000.0 0.47 653898.0 193000.0 0.42 0.6284 0.9981 1980140 ChemDiv1_021714 [O-][N+](=O)c1cccc2C(=O)N(C3C(N(C3=O)c4ccc(Cl)cc4[N+](=O)[O-])c5cccs5)C(=O)c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K23 mock treatment 687757.0 220000.0 0.45 682080.0 221000.0 0.48 0.6591 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 K24 mock treatment 251560.0 -216000.0 -0.45 213999.0 -247000.0 -0.54 -0.694 -0.9959 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L01 compound treatment 659488.0 192000.0 0.4 586361.0 125000.0 0.27 0.4713 0.9828 1980141 ChemDiv1_021715 COc1ccc(Br)cc1C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L02 compound treatment 935542.0 468000.0 0.97 862715.0 401000.0 0.87 1.2972 0.9986 1980142 ChemDiv1_021716 CCN1CC=C2C(C1)C(c3cccc(OC)c3OC)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L03 compound treatment 716702.0 249000.0 0.51 659168.0 198000.0 0.43 0.6663 0.9959 1686915 ChemDiv1_021717 Cc1cc(N2CCN(CC2)C3CCCCC3)n4c5ccccc5nc4c1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L04 compound treatment 851330.0 384000.0 0.79 767652.0 306000.0 0.66 1.0288 0.9961 1980143 ChemDiv1_021718 CC(C)Oc1ccc(cc1)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L05 compound treatment 759030.0 291000.0 0.6 682639.0 221000.0 0.48 0.764 0.9936 1124424 ChemDiv1_021719 N#Cc1c2CCCc2c(NCc3ccccc3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L06 compound treatment 668209.0 201000.0 0.41 678311.0 217000.0 0.47 0.6248 0.998 1980144 ChemDiv1_021720 Cc1ccc(NC2=C(CC(=O)O)C(N(C2=O)c3ccc(C)cc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L07 compound treatment 708796.0 241000.0 0.5 662426.0 201000.0 0.44 0.6597 0.9978 1197480 ChemDiv1_021721 CC1CN(CC(C)O1)c2cc(C)c(C#N)c3nc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L08 compound treatment 707803.0 240000.0 0.5 607901.0 147000.0 0.32 0.5748 0.9767 1186491 ChemDiv1_021722 CN(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L09 compound treatment 733713.0 266000.0 0.55 581086.0 120000.0 0.26 0.5716 0.9413 1940109 ChemDiv1_021723 CC1(C)Cc2[nH]c(=O)c(C#N)cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L10 compound treatment 718784.0 251000.0 0.52 637228.0 176000.0 0.38 0.6357 0.9885 1478763 ChemDiv1_021724 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccc(F)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L11 compound treatment 740497.0 273000.0 0.56 677126.0 216000.0 0.47 0.7285 0.9957 1980145 ChemDiv1_021725 COc1ccc(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/NC(=O)c3ccccc3Br)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L12 compound treatment 705062.0 237000.0 0.49 663090.0 202000.0 0.44 0.6553 0.9983 1378325 ChemDiv1_021726 Cc1ccc(C2NC(=O)c3c4CCCCc4sc3N2)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L13 compound treatment 712522.0 245000.0 0.51 672948.0 212000.0 0.46 0.6813 0.9988 1980146 ChemDiv1_021727 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cc(Cl)cc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L14 compound treatment 754832.0 287000.0 0.59 672582.0 211000.0 0.46 0.7425 0.9918 1980147 ChemDiv1_021728 COc1ccccc1NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L15 compound treatment 746958.0 279000.0 0.58 700172.0 239000.0 0.52 0.7732 0.9985 1980148 ChemDiv1_021729 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L16 compound treatment 703864.0 236000.0 0.49 696463.0 235000.0 0.51 0.7046 0.9998 1980149 ChemDiv1_021730 COc1ccccc1NC(=O)C2OC3OC4(CCCCC4)OC3C5OC6(CCCCC6)OC52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L17 compound treatment 737905.0 270000.0 0.56 716244.0 255000.0 0.55 0.7846 1.0 1980150 ChemDiv1_021731 Cc1ccc(cc1Cl)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L18 compound treatment 712096.0 244000.0 0.5 674170.0 213000.0 0.46 0.6825 0.999 1324461 ChemDiv1_021732 CCOc1cc(ccc1OCc2ccccc2F)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L19 compound treatment 690371.0 223000.0 0.46 700472.0 239000.0 0.52 0.6911 0.9983 1523523 ChemDiv1_021733 CC(C)CN(CC(C)C)Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L20 compound treatment 734311.0 267000.0 0.55 707932.0 247000.0 0.53 0.7666 0.9999 1736835 ChemDiv1_021734 CCOC(=O)c1ccc(Nc2nc3nonc3n4cnnc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L21 compound treatment 738819.0 271000.0 0.56 701909.0 241000.0 0.52 0.764 0.9993 1672692 ChemDiv1_021735 CN(Cc1c(O)ccc2c3CCCc3c(=O)oc12)C4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L22 compound treatment 726675.0 259000.0 0.53 672277.0 211000.0 0.46 0.7009 0.9969 1616644 ChemDiv1_021736 COc1ccc(cc1OC)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L23 mock treatment 748887.0 281000.0 0.58 687992.0 227000.0 0.49 0.7574 0.9965 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 L24 mock treatment 229266.0 -238000.0 -0.49 235445.0 -226000.0 -0.49 -0.6937 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M01 compound treatment 652867.0 185000.0 0.38 595247.0 134000.0 0.29 0.4753 0.9907 1980151 ChemDiv1_021737 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M02 compound treatment 606705.0 139000.0 0.29 629989.0 169000.0 0.37 0.4611 0.9929 1980152 ChemDiv1_021738 COc1ccc(Br)cc1C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M03 compound treatment 667641.0 200000.0 0.41 664726.0 203000.0 0.44 0.6032 0.9995 1669189 ChemDiv1_021739 CN(C)c1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M04 compound treatment 668955.0 201000.0 0.42 651153.0 190000.0 0.41 0.5843 1.0 1980153 ChemDiv1_021740 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(Cc5c(F)cccc5Cl)c6ccccc46)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M05 compound treatment 699979.0 232000.0 0.48 670210.0 209000.0 0.45 0.6588 0.9996 1513162 ChemDiv1_021741 COc1cccc(c1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5cc(OC)c(OC)c(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M06 compound treatment 671366.0 204000.0 0.42 657161.0 196000.0 0.42 0.597 1.0 1402007 ChemDiv1_021742 CCOC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M07 compound treatment 683244.0 216000.0 0.45 689827.0 228000.0 0.49 0.6644 0.9986 1980154 ChemDiv1_021743 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M08 compound treatment 677198.0 210000.0 0.43 652381.0 191000.0 0.41 0.5982 0.9997 1980155 ChemDiv1_021744 OC1=C(C(NC1=O)c2ccccc2)C(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M09 compound treatment 713570.0 246000.0 0.51 653543.0 192000.0 0.42 0.6531 0.9951 1531540 ChemDiv1_021745 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M10 compound treatment 670125.0 202000.0 0.42 636728.0 175000.0 0.38 0.5639 0.9988 1131378 ChemDiv1_021746 CCOC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)cc3)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M11 compound treatment 705500.0 238000.0 0.49 726183.0 265000.0 0.57 0.7525 0.997 1614437 ChemDiv1_021747 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M12 compound treatment 689433.0 222000.0 0.46 665518.0 204000.0 0.44 0.6362 0.9998 1449364 ChemDiv1_021748 CC(=O)Nc1ccc(cc1)N2C(=O)C3C4c5ccccc5C(c6ccccc46)C3(C)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M13 compound treatment 701286.0 234000.0 0.48 684348.0 223000.0 0.48 0.6823 1.0 1980156 ChemDiv1_021749 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5cc(Cl)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M14 compound treatment 717603.0 250000.0 0.52 658466.0 197000.0 0.43 0.6665 0.9955 1553250 ChemDiv1_021750 Cc1ccc2NC(=O)CC(c3ccccc3Cl)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M15 compound treatment 721406.0 254000.0 0.52 675605.0 214000.0 0.46 0.6983 0.9982 1489230 ChemDiv1_021751 Fc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M16 compound treatment 702900.0 235000.0 0.49 674297.0 213000.0 0.46 0.6693 0.9997 1980157 ChemDiv1_021752 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M17 compound treatment 698398.0 231000.0 0.48 710246.0 249000.0 0.54 0.7177 0.9981 1980158 ChemDiv1_021753 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M18 compound treatment 682171.0 215000.0 0.44 680488.0 219000.0 0.47 0.6485 0.9994 1980159 ChemDiv1_021754 Cc1ccc(F)cc1N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M19 compound treatment 701857.0 234000.0 0.48 714087.0 253000.0 0.55 0.7287 0.9981 1980160 ChemDiv1_021755 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M20 compound treatment 703490.0 236000.0 0.49 689467.0 228000.0 0.49 0.6934 1.0 1980161 ChemDiv1_021756 [O-][N+](=O)c1ccc2C(=O)N(C3C(N(C3=O)c4ccc(Br)cc4)c5cccs5)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M21 compound treatment 706492.0 239000.0 0.49 691309.0 230000.0 0.5 0.7006 1.0 1121581 ChemDiv1_021757 Clc1cccc(c1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M22 compound treatment 690336.0 223000.0 0.46 683418.0 222000.0 0.48 0.6649 0.9998 1980162 ChemDiv1_021758 COc1cc(cc(OC)c1OC)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5cc(Cl)cc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M23 mock treatment 708864.0 241000.0 0.5 724737.0 263000.0 0.57 0.7552 0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 M24 mock treatment 152844.0 -315000.0 -0.65 364445.0 -96900.0 -0.21 -0.6078 -0.8901 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N01 compound treatment 683650.0 216000.0 0.45 593683.0 132000.0 0.29 0.5178 0.9771 1980163 ChemDiv1_021759 Cc1cc(Cl)ccc1N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N02 compound treatment 689186.0 222000.0 0.46 634925.0 174000.0 0.38 0.589 0.9952 1782681 ChemDiv1_021760 CCOC(=O)N1CC=C2C(C1)C(c3ccc(OC)c(OC)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N03 compound treatment 690834.0 223000.0 0.46 674991.0 214000.0 0.46 0.6527 1.0 1422555 ChemDiv1_021761 Cc1cc(N2CCN(CC2)C(c3ccccc3)c4ccccc4Cl)n5c6ccccc6nc5c1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N04 compound treatment 715522.0 248000.0 0.51 667959.0 207000.0 0.45 0.678 0.9977 1980164 ChemDiv1_021762 CCCCOc1ccc(cc1OC)C2C3CN(CC=C3C(=C(N)C2(C#N)C#N)C#N)C(=O)OC(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N05 compound treatment 734780.0 267000.0 0.55 663282.0 202000.0 0.44 0.699 0.9934 1169676 ChemDiv1_021763 N#Cc1c2CCCc2c(NCc3ccco3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N06 compound treatment 668478.0 201000.0 0.41 628680.0 167000.0 0.36 0.5492 0.9977 1980165 ChemDiv1_021764 Clc1ccc(cc1)C2=NCCNC3=C2C(N(C3=O)c4ccccc4)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N07 compound treatment 732644.0 265000.0 0.55 663820.0 202000.0 0.44 0.6967 0.994 1234616 ChemDiv1_021765 Cc1cccc(c1)C(=O)N2CCN(CC2)c3cc(C)c(C#N)c4nc5ccccc5n34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N08 compound treatment 699857.0 232000.0 0.48 650951.0 190000.0 0.41 0.6291 0.997 1980166 ChemDiv1_021766 COc1ccc(cc1)C2N(C(=O)C(=C2CC(=O)O)Nc3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N09 compound treatment 636320.0 169000.0 0.35 669842.0 209000.0 0.45 0.5653 0.9918 1587556 ChemDiv1_021767 CC1(C)Cc2nc3[nH]c(=S)n(Cc4ccccc4)c(=O)c3cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N10 compound treatment 724128.0 256000.0 0.53 646920.0 186000.0 0.4 0.6584 0.9907 1291687 ChemDiv1_021768 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(Cl)cc2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N11 compound treatment 723613.0 256000.0 0.53 678598.0 217000.0 0.47 0.7061 0.9983 1980167 ChemDiv1_021769 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5cccc(Cl)c5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N12 compound treatment 691869.0 224000.0 0.46 636811.0 175000.0 0.38 0.5958 0.9952 1564066 ChemDiv1_021770 COc1ccc(cc1)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N13 compound treatment 708063.0 240000.0 0.5 669173.0 208000.0 0.45 0.669 0.9988 1980168 ChemDiv1_021771 Cc1ccc(Cl)cc1N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccc(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N14 compound treatment 628144.0 160000.0 0.33 658956.0 198000.0 0.43 0.5367 0.992 1980169 ChemDiv1_021772 CCOc1ccccc1NC(=O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]4OC(C)(C)O[C@H]42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N15 compound treatment 669898.0 202000.0 0.42 651154.0 190000.0 0.41 0.5857 1.0 1980170 ChemDiv1_021773 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N16 compound treatment 719137.0 251000.0 0.52 647058.0 186000.0 0.4 0.6513 0.992 1948435 ChemDiv1_021774 COCCOC(=O)C1=C(C)NC(=O)CC1c2cccc(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N17 compound treatment 755973.0 288000.0 0.6 675969.0 215000.0 0.46 0.7493 0.9925 1980171 ChemDiv1_021775 Cc1ccc(cc1F)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N18 compound treatment 718062.0 250000.0 0.52 621950.0 161000.0 0.35 0.6113 0.9814 1693170 ChemDiv1_021776 CCOC(=O)c1ccc(cc1)c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N19 compound treatment 728667.0 261000.0 0.54 690879.0 230000.0 0.5 0.7323 0.9992 1377870 ChemDiv1_021777 CN1CCN(Cc2c(O)ccc3c4CCCc4c(=O)oc23)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N20 compound treatment 711676.0 244000.0 0.5 683277.0 222000.0 0.48 0.6958 0.9997 1434056 ChemDiv1_021778 CCN(c1ccccc1)c2nc3nonc3n4c(C)nnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N21 compound treatment 727180.0 260000.0 0.54 698141.0 237000.0 0.51 0.7412 0.9998 1924397 ChemDiv1_021779 COCCN(CCOC)Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N22 compound treatment 705975.0 238000.0 0.49 657861.0 197000.0 0.43 0.6486 0.9974 1197495 ChemDiv1_021780 CC1=C(C(CC(=O)N1)c2cccc(Cl)c2Cl)C(=O)OCCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N23 mock treatment 712564.0 245000.0 0.51 669595.0 208000.0 0.45 0.6762 0.9984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 N24 mock treatment 218460.0 -249000.0 -0.51 118183.0 -343000.0 -0.74 -0.889 -0.9839 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O01 compound treatment 653991.0 186000.0 0.38 607317.0 146000.0 0.32 0.4954 0.9952 1980172 ChemDiv1_021781 CCCCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O02 compound treatment 627882.0 160000.0 0.33 608208.0 147000.0 0.32 0.4586 0.9998 1980173 ChemDiv1_021782 FC(F)(F)c1cccc(c1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O03 compound treatment 693929.0 226000.0 0.47 669261.0 208000.0 0.45 0.6485 0.9998 1688822 ChemDiv1_021783 COc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O04 compound treatment 641412.0 174000.0 0.36 632620.0 171000.0 0.37 0.5157 0.9999 1980174 ChemDiv1_021784 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(CC(=O)Nc5ccc6OCOc6c5)c7ccccc47)ccc8ccccc38 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O05 compound treatment 655149.0 187000.0 0.39 623119.0 162000.0 0.35 0.5213 0.9988 1980175 ChemDiv1_021785 Cc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(OC(F)F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O06 compound treatment 671773.0 204000.0 0.42 639312.0 178000.0 0.39 0.5703 0.999 1596235 ChemDiv1_021786 COc1ccc(cc1OC)C2N(CC=C)C(=O)C(=C2C(=O)c3ccc(Br)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O07 compound treatment 695244.0 228000.0 0.47 630661.0 169000.0 0.37 0.5913 0.9925 1163340 ChemDiv1_021787 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O08 compound treatment 662853.0 195000.0 0.4 628160.0 167000.0 0.36 0.5402 0.9985 1711302 ChemDiv1_021788 COc1ccc(cc1OC)C2NC(=O)C(=C2C(=O)c3ccc(Br)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O09 compound treatment 669168.0 201000.0 0.42 652920.0 192000.0 0.41 0.5873 1.0 1556796 ChemDiv1_021789 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(Cl)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O10 compound treatment 630895.0 163000.0 0.34 620008.0 159000.0 0.34 0.4811 1.0 1154226 ChemDiv1_021790 CCOC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)cc3)c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O11 compound treatment 697374.0 230000.0 0.47 655287.0 194000.0 0.42 0.6321 0.9982 1418043 ChemDiv1_021791 Cc1cc(C)cc(c1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O12 compound treatment 637349.0 170000.0 0.35 625773.0 164000.0 0.36 0.4993 1.0 1980176 ChemDiv1_021792 CC1(C2C3c4ccccc4C1c5ccccc35)C(=O)N(C2=O)c6ccc7ccccc7c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O13 compound treatment 680262.0 213000.0 0.44 668089.0 207000.0 0.45 0.6267 1.0 1980177 ChemDiv1_021793 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O14 compound treatment 674072.0 206000.0 0.43 623566.0 162000.0 0.35 0.5496 0.9954 1947380 ChemDiv1_021794 CC(C)OCCOC(=O)C1=C(C)NC2(O)c3ccccc3C(=O)C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O15 compound treatment 707041.0 239000.0 0.49 646803.0 185000.0 0.4 0.6333 0.9947 1980178 ChemDiv1_021795 CCOc1ccc(cc1)C2C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C(=O)N2c5ccc(Br)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O16 compound treatment 667203.0 200000.0 0.41 638893.0 178000.0 0.38 0.563 0.9994 1980179 ChemDiv1_021796 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5ccc(Cl)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O17 compound treatment 728870.0 261000.0 0.54 672526.0 211000.0 0.46 0.7045 0.9966 1980180 ChemDiv1_021797 CCCCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(C)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O18 compound treatment 691334.0 224000.0 0.46 625489.0 164000.0 0.36 0.5777 0.9916 1980181 ChemDiv1_021798 Clc1ccc(cc1Cl)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O19 compound treatment 716032.0 248000.0 0.51 657578.0 196000.0 0.42 0.6629 0.9956 1600400 ChemDiv1_021799 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(OCC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O20 compound treatment 748666.0 281000.0 0.58 654132.0 193000.0 0.42 0.7052 0.9869 1980182 ChemDiv1_021800 COc1cccc(c1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O21 compound treatment 715062.0 247000.0 0.51 668158.0 207000.0 0.45 0.6776 0.9978 1376766 ChemDiv1_021801 Cc1ccc(cc1)N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O22 compound treatment 662044.0 194000.0 0.4 637147.0 176000.0 0.38 0.5528 0.9996 1980183 ChemDiv1_021802 Cc1ccc(cc1F)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O23 mock treatment 655992.0 188000.0 0.39 629361.0 168000.0 0.36 0.532 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 O24 mock treatment 203684.0 -264000.0 -0.54 398405.0 -62900.0 -0.14 -0.4817 -0.8575 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P01 compound treatment 687592.0 220000.0 0.45 571225.0 110000.0 0.24 0.4892 0.9545 1980184 ChemDiv1_021803 Cc1ccc(cc1Cl)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P02 compound treatment 865485.0 398000.0 0.82 747471.0 286000.0 0.62 1.0186 0.9903 1174050 ChemDiv1_021804 COc1ccc(cc1)C2C3CN(C)CC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P03 compound treatment 696448.0 229000.0 0.47 604940.0 144000.0 0.31 0.5537 0.9794 1161174 ChemDiv1_021805 N#Cc1c2CCCc2c(N3CCOCC3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P04 compound treatment 921597.0 454000.0 0.94 1019490.0 558000.0 1.21 1.5168 0.9921 1980185 ChemDiv1_021806 CC(C)(C)C(=O)C1C(c2ccc(Br)cc2)C(C#N)(C#N)C3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P05 compound treatment 692907.0 225000.0 0.46 616692.0 155000.0 0.34 0.5665 0.9873 1337529 ChemDiv1_021807 N#Cc1c2CCCc2c(NCCc3ccccc3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P06 compound treatment 688955.0 221000.0 0.46 602655.0 141000.0 0.31 0.5393 0.981 1165924 ChemDiv1_021808 CC(=O)NCCN1C(C(=C(O)C1=O)C(=O)c2ccc(Cl)cc2)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P07 compound treatment 691042.0 223000.0 0.46 609302.0 148000.0 0.32 0.5525 0.9841 1230092 ChemDiv1_021809 N#Cc1c2CCCc2c(N3CCCC3)n4c5ccccc5nc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P08 compound treatment 697575.0 230000.0 0.47 613934.0 153000.0 0.33 0.5691 0.9843 1980186 ChemDiv1_021810 OC(=O)CN1C(C(=C(O)C1=O)C(=O)c2ccc(Br)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P09 compound treatment 696418.0 229000.0 0.47 629004.0 168000.0 0.36 0.5905 0.9915 1501299 ChemDiv1_021811 CCOC(=O)C1=C(NC(=O)Cc2ccccc2)c3ccccc3CC41CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P10 compound treatment 686056.0 218000.0 0.45 591029.0 130000.0 0.28 0.5173 0.974 1309381 ChemDiv1_021812 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4F)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P11 compound treatment 714426.0 247000.0 0.51 612213.0 151000.0 0.33 0.5911 0.9769 1269949 ChemDiv1_021813 COc1ccc(cc1)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cc(OC)ccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P12 compound treatment 723824.0 256000.0 0.53 641655.0 180000.0 0.39 0.6499 0.9888 1663303 ChemDiv1_021814 COc1ccc(cc1OC)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P13 compound treatment 690286.0 223000.0 0.46 664469.0 203000.0 0.44 0.6358 0.9998 1980187 ChemDiv1_021815 COc1ccc(OC)c(c1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P14 compound treatment 755489.0 288000.0 0.59 590364.0 129000.0 0.28 0.6176 0.9407 1980188 ChemDiv1_021816 CC(C)COc1ccccc1NC(=O)C2OC3OC(C)(C)OC3C4OC(C)(C)OC42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P15 compound treatment 792091.0 324000.0 0.67 711655.0 250000.0 0.54 0.8566 0.9945 1944997 ChemDiv1_021817 COc1ccc(NC2=Nc3cccc4cccc2c34)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P16 compound treatment 688567.0 221000.0 0.46 606682.0 145000.0 0.31 0.5449 0.9836 1714085 ChemDiv1_021818 CC1=C(C(CC(=O)N1)c2cccc(Cl)c2)C(=O)OCCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P17 compound treatment 704213.0 237000.0 0.49 630298.0 169000.0 0.37 0.6039 0.9899 1980189 ChemDiv1_021819 Cc1cc(ccc1Br)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P18 compound treatment 720549.0 253000.0 0.52 637939.0 177000.0 0.38 0.6394 0.9883 1980190 ChemDiv1_021820 CCOc1cc(ccc1OCc2ccccc2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P19 compound treatment 696272.0 229000.0 0.47 625676.0 164000.0 0.36 0.5852 0.9903 1374577 ChemDiv1_021821 Oc1ccc2c3CCCc3c(=O)oc2c1CN4CCCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P20 compound treatment 723163.0 255000.0 0.53 632512.0 171000.0 0.37 0.6349 0.9851 1250799 ChemDiv1_021822 CN1C(=O)CC2CC1(C)Oc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P21 compound treatment 713296.0 246000.0 0.51 603054.0 142000.0 0.31 0.5754 0.971 1123899 ChemDiv1_021823 CN(Cc1ccccc1)Cc2c(O)ccc3c4CCCc4c(=O)oc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P22 compound treatment 691186.0 224000.0 0.46 630837.0 169000.0 0.37 0.5857 0.9935 1948989 ChemDiv1_021824 COCCOC(=O)C1=C(C)NC(=O)CC1c2cccc(Cl)c2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P23 mock treatment 671664.0 204000.0 0.42 607480.0 146000.0 0.32 0.5214 0.9901 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.648 P24 mock treatment 237644.0 -230000.0 -0.47 435694.0 -25600.0 -0.06 -0.375 -0.7844 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A01 compound treatment 691023.0 217000.0 0.45 596299.0 106000.0 0.23 0.4797 0.9522 1640229 ChemDiv1_021825 Clc1ccc(cc1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A02 compound treatment 658170.0 184000.0 0.38 592368.0 103000.0 0.22 0.4257 0.9671 1980191 ChemDiv1_021826 Clc1ccc2N=C(NN=C(c3ccccc3)c2c1)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A03 compound treatment 700914.0 227000.0 0.47 626668.0 137000.0 0.3 0.5406 0.9755 1738949 ChemDiv1_021827 CC1C(NC(C(C)C1(O)CC=C)c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A04 compound treatment 677916.0 204000.0 0.42 612524.0 123000.0 0.27 0.4854 0.9753 1313428 ChemDiv1_021828 CCCCN(CC)Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A05 compound treatment 688283.0 214000.0 0.44 613505.0 124000.0 0.27 0.502 0.971 1980192 ChemDiv1_021829 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A06 compound treatment 708177.0 234000.0 0.48 642838.0 153000.0 0.33 0.5759 0.983 1158535 ChemDiv1_021830 OC1=C(C(N(C1=O)c2nncs2)c3cccc(Br)c3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A07 compound treatment 730100.0 256000.0 0.53 649047.0 159000.0 0.34 0.6174 0.9785 1566908 ChemDiv1_021831 O=C1NC(Nc2sc3CCCCc3c12)c4ccc(OCc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A08 compound treatment 741904.0 268000.0 0.55 645091.0 155000.0 0.34 0.6286 0.9715 1387811 ChemDiv1_021832 Cc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A09 compound treatment 736277.0 262000.0 0.54 650109.0 160000.0 0.35 0.6281 0.9768 1360882 ChemDiv1_021833 COc1ccc(C2NC(=O)c3c4CCCCc4sc3N2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A10 compound treatment 719969.0 246000.0 0.51 660192.0 170000.0 0.37 0.6197 0.9876 1233773 ChemDiv1_021834 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Br)c3)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A11 compound treatment 723190.0 249000.0 0.51 659303.0 169000.0 0.37 0.6231 0.9863 1782252 ChemDiv1_021835 [O-][N+](=O)c1ccc(cc1)c2nc3ccccc3nc2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A12 compound treatment 710544.0 237000.0 0.49 650688.0 161000.0 0.35 0.5914 0.9862 1980193 ChemDiv1_021836 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(c3)[N+](=O)[O-])c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A13 compound treatment 693595.0 220000.0 0.45 631251.0 141000.0 0.31 0.5369 0.9817 1166186 ChemDiv1_021837 Oc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A14 compound treatment 724427.0 250000.0 0.52 653570.0 164000.0 0.35 0.6161 0.983 1980194 ChemDiv1_021838 C/C(=N\OCC(=O)Nc1oc(c(c1C#N)c2ccccc2)c3ccccc3)/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A15 compound treatment 707590.0 234000.0 0.48 652562.0 163000.0 0.35 0.59 0.9881 1980195 ChemDiv1_021839 COc1cccc(c1)c2nc(c([nH]2)c3cc(ccc3C)[N+](=O)[O-])c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A16 compound treatment 737307.0 263000.0 0.54 640594.0 151000.0 0.33 0.615 0.9702 1784609 ChemDiv1_021840 c1ccc(cc1)c2oc3ncn4nc(nc4c3c2c5ccccc5)c6ccncc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A17 compound treatment 710090.0 236000.0 0.49 657425.0 168000.0 0.36 0.6011 0.9894 1648847 ChemDiv1_021841 Cc1cccc(c1C)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A18 compound treatment 715872.0 242000.0 0.5 653141.0 163000.0 0.35 0.6029 0.9857 1980196 ChemDiv1_021842 COc1ccc(/C=N/OCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A19 compound treatment 707533.0 234000.0 0.48 648606.0 159000.0 0.34 0.5838 0.9862 1719541 ChemDiv1_021843 CC(=O)Nc1nc2CCCCc2c3c4ccccc4oc(=O)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A20 compound treatment 713902.0 240000.0 0.5 629595.0 140000.0 0.3 0.564 0.972 1980197 ChemDiv1_021844 CC(C)NC(=O)/C(=C/c1cn(nc1c2cccc(c2)[N+](=O)[O-])c3ccccc3)/NC(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A21 compound treatment 705304.0 231000.0 0.48 665477.0 176000.0 0.38 0.6064 0.9936 1285762 ChemDiv1_021845 COC(=O)CN1C2NC(=O)NC2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A22 compound treatment 690034.0 216000.0 0.45 619773.0 130000.0 0.28 0.5142 0.9753 1980198 ChemDiv1_021846 Cc1ccc(cc1)c2nc3sc(=Cc4ccc(Cl)cc4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A23 mock treatment 650504.0 176000.0 0.36 598162.0 108000.0 0.23 0.4234 0.9773 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 A24 mock treatment 209590.0 -264000.0 -0.55 240167.0 -250000.0 -0.54 -0.7681 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B01 compound treatment 674924.0 201000.0 0.41 595935.0 106000.0 0.23 0.4556 0.9611 1626643 ChemDiv1_021847 Cc1ccc(O)c(c1)C2N(Cc3ccccc3O)CCN2Cc4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B02 compound treatment 714420.0 240000.0 0.5 636874.0 147000.0 0.32 0.5759 0.9769 1980199 ChemDiv1_021848 Brc1ccc(cc1)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B03 compound treatment 687365.0 213000.0 0.44 642073.0 152000.0 0.33 0.5444 0.9898 1048962 ChemDiv1_021849 N1C(Nc2cccc3cccc1c23)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B04 compound treatment 730859.0 257000.0 0.53 648589.0 159000.0 0.34 0.6179 0.9779 1980200 ChemDiv1_021850 Clc1ccc(cc1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B05 compound treatment 723472.0 249000.0 0.51 679908.0 190000.0 0.41 0.655 0.9938 1235433 ChemDiv1_021851 CC(C)(C)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B06 compound treatment 754042.0 280000.0 0.58 665734.0 176000.0 0.38 0.6779 0.9795 1947245 ChemDiv1_021852 C(CN1CCCCC1)N2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B07 compound treatment 743160.0 269000.0 0.56 685822.0 196000.0 0.42 0.6928 0.9911 1327601 ChemDiv1_021853 Oc1ccccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B08 compound treatment 755594.0 282000.0 0.58 706414.0 217000.0 0.47 0.7425 0.9943 1659065 ChemDiv1_021854 OC(=O)CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B09 compound treatment 761041.0 287000.0 0.59 692028.0 202000.0 0.44 0.7284 0.9889 1564801 ChemDiv1_021855 COc1cc(ccc1O)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B10 compound treatment 745135.0 271000.0 0.56 708733.0 219000.0 0.47 0.7307 0.9966 1284661 ChemDiv1_021856 Cc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3C)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B11 compound treatment 760123.0 286000.0 0.59 723699.0 234000.0 0.51 0.7755 0.997 1725870 ChemDiv1_021857 CCCOc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B12 compound treatment 726801.0 253000.0 0.52 663409.0 174000.0 0.38 0.6346 0.987 1566162 ChemDiv1_021858 O=c1n2CCCCc2nc3sc4CCCCCc4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B13 compound treatment 774832.0 301000.0 0.62 716617.0 227000.0 0.49 0.7862 0.9932 1980201 ChemDiv1_021859 Brc1ccc(cc1)c2nc3ccccc3nc2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B14 compound treatment 740095.0 266000.0 0.55 708915.0 219000.0 0.47 0.7237 0.9973 1128553 ChemDiv1_021860 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccc(Br)cc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B15 compound treatment 768244.0 294000.0 0.61 720571.0 231000.0 0.5 0.7826 0.9953 1449798 ChemDiv1_021861 CC(C)(C)NCC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B16 compound treatment 762454.0 288000.0 0.6 702977.0 213000.0 0.46 0.7472 0.992 1166765 ChemDiv1_021862 CCOc1ccccc1NC(=O)c2c(NC(=O)COc3ccccc3)sc4CCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B17 compound treatment 793987.0 320000.0 0.66 754950.0 265000.0 0.57 0.8728 0.9975 1980202 ChemDiv1_021863 Cc1nn(CC(O)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6)c(C)c1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B18 compound treatment 732711.0 259000.0 0.53 697990.0 208000.0 0.45 0.6962 0.9964 1951829 ChemDiv1_021864 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(cc4)C(F)(F)F)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B19 compound treatment 731756.0 258000.0 0.53 706854.0 217000.0 0.47 0.7083 0.9981 1665736 ChemDiv1_021865 CCOC(=O)C1=C(N)Oc2ccc3ccccc3c2C1c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B20 compound treatment 704682.0 231000.0 0.48 685111.0 195000.0 0.42 0.6355 0.9982 1980203 ChemDiv1_021866 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B21 compound treatment 742554.0 269000.0 0.55 710884.0 221000.0 0.48 0.7303 0.9973 1980204 ChemDiv1_021867 CCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B22 compound treatment 706130.0 232000.0 0.48 680454.0 191000.0 0.41 0.6305 0.9972 1980205 ChemDiv1_021868 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(C#N)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B23 mock treatment 702082.0 228000.0 0.47 660607.0 171000.0 0.37 0.5942 0.9928 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 B24 mock treatment 217287.0 -257000.0 -0.53 225360.0 -264000.0 -0.57 -0.7795 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C01 compound treatment 723163.0 249000.0 0.51 623477.0 134000.0 0.29 0.5682 0.9629 1268232 ChemDiv1_021869 CCc1ccc(cc1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C02 compound treatment 714136.0 240000.0 0.5 645604.0 156000.0 0.34 0.5889 0.9823 1305594 ChemDiv1_021870 CC(=O)Oc1ccc(cc1)c2cc(nc(n2)c3ccccc3)c4ccc(OC(=O)C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C03 compound treatment 735553.0 262000.0 0.54 705630.0 216000.0 0.47 0.712 0.9974 1257770 ChemDiv1_021871 CCC1C(NC(CC1(C)O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C04 compound treatment 735593.0 262000.0 0.54 696212.0 206000.0 0.45 0.6976 0.9956 1144573 ChemDiv1_021872 Brc1ccc(cc1)C(=O)NC(=S)N2CC3CC(C2)c4cccc(=O)n4C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C05 compound treatment 763328.0 289000.0 0.6 705310.0 215000.0 0.47 0.7521 0.9925 1980206 ChemDiv1_021873 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccc4OCOc4c3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C06 compound treatment 743916.0 270000.0 0.56 682523.0 193000.0 0.42 0.6888 0.9898 1207806 ChemDiv1_021874 OC1=C(C(N(C1=O)c2nncs2)c3ccc(Cl)cc3Cl)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C07 compound treatment 1064115.0 590000.0 1.22 1033838.0 544000.0 1.18 1.6939 0.9999 1529709 ChemDiv1_021875 COc1cc(ccc1O)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C08 compound treatment 775903.0 302000.0 0.62 689753.0 200000.0 0.43 0.7466 0.9841 1483448 ChemDiv1_021876 CC(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C09 compound treatment 781989.0 308000.0 0.64 744731.0 255000.0 0.55 0.8396 0.9975 1589096 ChemDiv1_021877 Fc1ccccc1C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C10 compound treatment 746992.0 273000.0 0.56 726790.0 237000.0 0.51 0.7611 0.9989 1434818 ChemDiv1_021878 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Cl)c3)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C11 compound treatment 786007.0 312000.0 0.64 766687.0 277000.0 0.6 0.8791 0.9993 1980207 ChemDiv1_021879 OC(=O)c1ccc2nc(c3ccc(C#Cc4ccccc4)cc3)c(nc2c1)c5ccc(C#Cc6ccccc6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C12 compound treatment 759178.0 285000.0 0.59 744853.0 255000.0 0.55 0.8065 0.9995 1543391 ChemDiv1_021880 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C13 compound treatment 754855.0 281000.0 0.58 742875.0 253000.0 0.55 0.7972 0.9996 1118344 ChemDiv1_021881 Oc1ccccc1c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C14 compound treatment 766067.0 292000.0 0.6 755613.0 266000.0 0.58 0.833 0.9997 1980208 ChemDiv1_021882 Clc1ccccc1/C=N/OCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C15 compound treatment 783735.0 310000.0 0.64 737137.0 247000.0 0.54 0.8306 0.9961 1224396 ChemDiv1_021883 CCCCn1c(=O)nc2n(c3ccccc3C)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C16 compound treatment 752149.0 278000.0 0.57 757439.0 268000.0 0.58 0.8155 1.0 1980209 ChemDiv1_021884 C(Oc1ccccc1)c2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C17 compound treatment 812182.0 338000.0 0.7 834206.0 344000.0 0.75 1.0206 0.9995 1314159 ChemDiv1_021885 COc1ccc(OC)c(c1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C18 compound treatment 706383.0 232000.0 0.48 737842.0 248000.0 0.54 0.7187 0.9984 1980210 ChemDiv1_021886 C/C(=N\OCc1nc2c3c(c(oc3ncn2n1)c4ccccc4)c5ccccc5)/c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C19 compound treatment 728457.0 254000.0 0.53 717352.0 227000.0 0.49 0.7196 0.9995 1176552 ChemDiv1_021887 CC1NC(=O)N(C)C2NC(=O)N(C)C(C12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C20 compound treatment 722086.0 248000.0 0.51 679429.0 190000.0 0.41 0.6522 0.994 1980211 ChemDiv1_021888 CC(C)c1ccc(/C=C(\NC(=O)c2ccc(C)cc2)/C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C21 compound treatment 750571.0 277000.0 0.57 682341.0 192000.0 0.42 0.6983 0.988 1980212 ChemDiv1_021889 Cc1ccc(cc1)C(=O)N/C(=C\c2ccccc2)/C(=O)NCCCn3ccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C22 compound treatment 723521.0 250000.0 0.52 694223.0 204000.0 0.44 0.677 0.9971 1980213 ChemDiv1_021890 CC(C)(C)c1cc2oc3CCCCc3c2cc1OC(=O)c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C23 mock treatment 726561.0 253000.0 0.52 712511.0 223000.0 0.48 0.7094 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 C24 mock treatment 232795.0 -241000.0 -0.5 238858.0 -251000.0 -0.54 -0.7362 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D01 compound treatment 672620.0 199000.0 0.41 627429.0 138000.0 0.3 0.5005 0.9877 1550644 ChemDiv1_021891 Oc1ccccc1CN2CCN(Cc3ccccc3O)C2c4c5ccccc5cc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D02 compound treatment 699943.0 226000.0 0.47 632603.0 143000.0 0.31 0.5483 0.98 1980214 ChemDiv1_021892 Clc1ccc(cc1)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D03 compound treatment 724237.0 250000.0 0.52 649987.0 160000.0 0.35 0.6103 0.9812 1342899 ChemDiv1_021893 COc1ccc(Br)cc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D04 compound treatment 719148.0 245000.0 0.51 666566.0 177000.0 0.38 0.6283 0.9905 1937501 ChemDiv1_021894 Brc1ccc(cc1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D05 compound treatment 694369.0 220000.0 0.45 673253.0 183000.0 0.4 0.6023 0.9977 1162626 ChemDiv1_021895 Clc1ccc(cc1Cl)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D06 compound treatment 704028.0 230000.0 0.47 668515.0 179000.0 0.39 0.6092 0.9948 1947815 ChemDiv1_021896 C(CN1CCOCC1)N2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D07 compound treatment 751435.0 277000.0 0.57 640705.0 151000.0 0.33 0.6358 0.9645 1048071 ChemDiv1_021897 COc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D08 compound treatment 728402.0 254000.0 0.53 702880.0 213000.0 0.46 0.6974 0.9979 1377043 ChemDiv1_021898 CC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D09 compound treatment 732661.0 259000.0 0.53 727031.0 237000.0 0.51 0.7405 0.9998 1444238 ChemDiv1_021899 Cc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D10 compound treatment 745353.0 271000.0 0.56 722291.0 232000.0 0.5 0.7518 0.9986 1124636 ChemDiv1_021900 Cc1ccc(cc1)C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D11 compound treatment 771141.0 297000.0 0.61 737154.0 247000.0 0.54 0.8122 0.9977 1238510 ChemDiv1_021901 COc1cc(OC)c(C2Nc3cccc4cccc(N2)c34)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D12 compound treatment 722113.0 248000.0 0.51 701108.0 211000.0 0.46 0.6855 0.9984 1332582 ChemDiv1_021902 Cc1ccc(NC(=O)c2c(NC(=O)c3ccccc3Br)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D13 compound treatment 760129.0 286000.0 0.59 684218.0 194000.0 0.42 0.7151 0.9862 1188114 ChemDiv1_021903 Fc1ccc(cc1)c2nc3ccccc3nc2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D14 compound treatment 762429.0 288000.0 0.6 689847.0 200000.0 0.43 0.7271 0.9877 1715945 ChemDiv1_021904 Cc1ccc(NC(=O)c2c(NC(=O)c3ccccc3Cl)sc4CCCCCc24)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D15 compound treatment 771203.0 297000.0 0.61 749102.0 259000.0 0.56 0.8306 0.999 1336365 ChemDiv1_021905 CC1(C)C2CCC1(C)CN(CC(O)Cn3c4ccccc4c5cc(I)ccc35)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D16 compound treatment 724210.0 250000.0 0.52 719985.0 230000.0 0.5 0.7174 0.9998 1174455 ChemDiv1_021906 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3F)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D17 compound treatment 778230.0 304000.0 0.63 738051.0 248000.0 0.54 0.8239 0.997 1417165 ChemDiv1_021907 Cc1cc(C)n(CC(O)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D18 compound treatment 702567.0 229000.0 0.47 663199.0 173000.0 0.38 0.5989 0.9936 1951755 ChemDiv1_021908 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4C(F)(F)F)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D19 compound treatment 735667.0 262000.0 0.54 661590.0 172000.0 0.37 0.6448 0.9834 1738280 ChemDiv1_021909 CCOC(=O)C1=C(N)Oc2ccc3ccccc3c2C1c4cccc(O)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D20 compound treatment 704779.0 231000.0 0.48 671351.0 181000.0 0.39 0.6146 0.9954 1980215 ChemDiv1_021910 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cccc(O)c4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D21 compound treatment 730807.0 257000.0 0.53 687855.0 198000.0 0.43 0.6779 0.9944 1980216 ChemDiv1_021911 CCCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D22 compound treatment 725555.0 252000.0 0.52 681651.0 192000.0 0.42 0.6607 0.9938 1980217 ChemDiv1_021912 COc1ccccc1C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D23 mock treatment 706839.0 233000.0 0.48 772808.0 283000.0 0.61 0.7729 0.9928 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 D24 mock treatment 225423.0 -249000.0 -0.51 231099.0 -259000.0 -0.56 -0.7589 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E01 compound treatment 691478.0 217000.0 0.45 622059.0 132000.0 0.29 0.5198 0.9763 1727174 ChemDiv1_021913 CCCC1(O)C(C)C(NC(C1C)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E02 compound treatment 694339.0 220000.0 0.45 638505.0 149000.0 0.32 0.5491 0.9856 1493068 ChemDiv1_021914 Cc1ccc2n3CCN(Cc4ccccc4)C5CCCc(c53)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E03 compound treatment 745065.0 271000.0 0.56 697808.0 208000.0 0.45 0.7139 0.9942 1225454 ChemDiv1_021915 CCCC1C(NC(CC1(C)O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E04 compound treatment 712054.0 238000.0 0.49 686461.0 197000.0 0.43 0.6484 0.9974 1739666 ChemDiv1_021916 O=c1[nH]nc(c2ccccc2)c(=O)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E05 compound treatment 775579.0 302000.0 0.62 721066.0 231000.0 0.5 0.7941 0.9941 1980218 ChemDiv1_021917 CC(=O)NC1=NN(C(O1)c2cccc(c2)[N+](=O)[O-])C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E06 compound treatment 715331.0 241000.0 0.5 712706.0 223000.0 0.48 0.6933 0.9999 1691020 ChemDiv1_021918 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4nccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E07 compound treatment 751487.0 277000.0 0.57 731162.0 241000.0 0.52 0.7743 0.9989 1647534 ChemDiv1_021919 O=C1NC(Nc2sc3CCCCc3c12)c4ccccc4OCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E08 compound treatment 749957.0 276000.0 0.57 732483.0 243000.0 0.53 0.7741 0.9992 1707538 ChemDiv1_021920 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(cc3)C(C)(C)C)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E09 compound treatment 786392.0 312000.0 0.64 749096.0 259000.0 0.56 0.8527 0.9976 1579989 ChemDiv1_021921 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E10 compound treatment 768318.0 294000.0 0.61 750571.0 261000.0 0.56 0.8286 0.9993 1500576 ChemDiv1_021922 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Br)c3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E11 compound treatment 741710.0 268000.0 0.55 746362.0 257000.0 0.56 0.7833 1.0 1218836 ChemDiv1_021923 Fc1ccc(cc1)C(=O)c2ccc(cc2)c3nc4ccccc4nc3c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E12 compound treatment 752595.0 279000.0 0.58 706021.0 216000.0 0.47 0.7375 0.9948 1293617 ChemDiv1_021924 O=C(CN1C(=O)c2ccccc2C1=O)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E13 compound treatment 722303.0 248000.0 0.51 716963.0 227000.0 0.49 0.71 0.9998 1333796 ChemDiv1_021925 Oc1ccc(cc1O)c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E14 compound treatment 731988.0 258000.0 0.53 740895.0 251000.0 0.54 0.7608 0.9999 1980219 ChemDiv1_021926 COc1ccc(/C=N/OCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E15 compound treatment 764876.0 291000.0 0.6 747199.0 257000.0 0.56 0.8184 0.9993 1277411 ChemDiv1_021927 CCCCn1c(=O)nc2n(c3ccc(C)cc3C)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E16 compound treatment 746477.0 272000.0 0.56 711702.0 222000.0 0.48 0.7372 0.9969 1980220 ChemDiv1_021928 COc1ccc(/C=N/OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E17 compound treatment 790055.0 316000.0 0.65 760962.0 271000.0 0.59 0.8762 0.9986 1683966 ChemDiv1_021929 COc1ccc(cc1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E18 compound treatment 729184.0 255000.0 0.53 743429.0 254000.0 0.55 0.7606 0.9998 1980221 ChemDiv1_021930 COc1cc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E19 compound treatment 717528.0 244000.0 0.5 684329.0 194000.0 0.42 0.6531 0.9961 1922680 ChemDiv1_021931 CCCCN1C2C(N(C)C1=O)N(CCCC)C(=O)N2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E20 compound treatment 733156.0 259000.0 0.53 707782.0 218000.0 0.47 0.7118 0.998 1980222 ChemDiv1_021932 Cc1c(NC(=O)/C(=C/c2cccc3ccccc23)/C#N)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E21 compound treatment 744163.0 270000.0 0.56 740134.0 250000.0 0.54 0.7774 0.9999 1980223 ChemDiv1_021933 Cc1c(NC(=O)/C=C/c2ccc(Cl)cc2)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E22 compound treatment 748579.0 275000.0 0.57 694403.0 205000.0 0.44 0.7138 0.9925 1151811 ChemDiv1_021934 CC(C)(C)c1cc2oc3CCCCc3c2cc1OC(=O)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E23 mock treatment 718677.0 245000.0 0.51 717240.0 227000.0 0.49 0.7051 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 E24 mock treatment 218543.0 -255000.0 -0.53 243393.0 -246000.0 -0.53 -0.7501 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F01 compound treatment 706559.0 233000.0 0.48 618574.0 129000.0 0.28 0.5364 0.9665 1353790 ChemDiv1_021935 CCCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F02 compound treatment 672920.0 199000.0 0.41 642312.0 152000.0 0.33 0.5237 0.9941 1980224 ChemDiv1_021936 Clc1ccc(cc1Cl)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F03 compound treatment 672962.0 199000.0 0.41 686970.0 197000.0 0.43 0.5921 0.9998 1493467 ChemDiv1_021937 Clc1cccc(C2Nc3cccc4cccc(N2)c34)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F04 compound treatment 726090.0 252000.0 0.52 666272.0 176000.0 0.38 0.638 0.9884 1947350 ChemDiv1_021938 COc1ccc(cc1OC)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F05 compound treatment 690068.0 216000.0 0.45 710643.0 221000.0 0.48 0.6533 0.9994 1457387 ChemDiv1_021939 COc1ccc(C2Nc3cccc4cccc(N2)c34)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F06 compound treatment 728265.0 254000.0 0.52 681612.0 192000.0 0.42 0.6646 0.9932 1254692 ChemDiv1_021940 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F07 compound treatment 720372.0 246000.0 0.51 713617.0 224000.0 0.48 0.7021 0.9997 1608513 ChemDiv1_021941 Clc1ccc(C2Nc3cccc4cccc(N2)c34)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F08 compound treatment 753594.0 280000.0 0.58 713649.0 224000.0 0.48 0.7506 0.9962 1350126 ChemDiv1_021942 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F09 compound treatment 723477.0 249000.0 0.51 721168.0 231000.0 0.5 0.7182 0.9999 1510036 ChemDiv1_021943 CCOc1cc(ccc1O)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F10 compound treatment 719985.0 246000.0 0.51 720959.0 231000.0 0.5 0.7127 1.0 1538462 ChemDiv1_021944 COc1ccc(NC(=O)c2c(NC(=O)c3ccccc3C)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F11 compound treatment 740969.0 267000.0 0.55 708395.0 219000.0 0.47 0.7241 0.9971 1928029 ChemDiv1_021945 FC(F)(F)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F12 compound treatment 728848.0 255000.0 0.53 712459.0 223000.0 0.48 0.7127 0.999 1231765 ChemDiv1_021946 COc1ccc(NC(=O)c2c(NC(=O)c3cccc(Br)c3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F13 compound treatment 719057.0 245000.0 0.51 688061.0 198000.0 0.43 0.661 0.9966 1980225 ChemDiv1_021947 Cc1ccc(cc1C)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F14 compound treatment 748086.0 274000.0 0.57 686275.0 196000.0 0.43 0.7007 0.9901 1261374 ChemDiv1_021948 Cc1ccc(NC(=O)c2c(NC(=O)c3ccccc3F)sc4CCCCCc24)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F15 compound treatment 789467.0 315000.0 0.65 740083.0 250000.0 0.54 0.8434 0.9958 1372484 ChemDiv1_021949 OC(CN1CCCCC1)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F16 compound treatment 762182.0 288000.0 0.59 697520.0 208000.0 0.45 0.7385 0.9904 1475677 ChemDiv1_021950 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3Cl)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F17 compound treatment 746875.0 273000.0 0.56 752847.0 263000.0 0.57 0.8008 1.0 1980226 ChemDiv1_021951 Cc1ccc(NCC(O)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F18 compound treatment 703321.0 229000.0 0.47 712348.0 222000.0 0.48 0.6752 1.0 1980227 ChemDiv1_021952 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5ccc(cc5)C(C)(C)C)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F19 compound treatment 704841.0 231000.0 0.48 693202.0 203000.0 0.44 0.6482 0.9992 1784610 ChemDiv1_021953 CCOC(=O)C1=C(N)Oc2ccc3ccccc3c2C1c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F20 compound treatment 721870.0 248000.0 0.51 696855.0 207000.0 0.45 0.6786 0.9978 1980228 ChemDiv1_021954 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4Cl)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F21 compound treatment 739936.0 266000.0 0.55 717624.0 228000.0 0.49 0.7368 0.9986 1980229 ChemDiv1_021955 CCCCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F22 compound treatment 724086.0 250000.0 0.52 696131.0 206000.0 0.45 0.6807 0.9974 1980230 ChemDiv1_021956 CCOc1ccc(cc1)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F23 mock treatment 706162.0 232000.0 0.48 702461.0 213000.0 0.46 0.6643 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 F24 mock treatment 215580.0 -258000.0 -0.53 253634.0 -236000.0 -0.51 -0.7388 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G01 compound treatment 681661.0 208000.0 0.43 617921.0 128000.0 0.28 0.4991 0.9777 1106730 ChemDiv1_021957 CC1C(O)C(C)C(NC1c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G02 compound treatment 732861.0 259000.0 0.53 624268.0 134000.0 0.29 0.5836 0.9591 1416584 ChemDiv1_021958 CC(=O)N1CCn2c3C1CCCc3c4cc(C)ccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G03 compound treatment 718945.0 245000.0 0.51 707242.0 217000.0 0.47 0.6902 0.9994 1512321 ChemDiv1_021959 CCCC1C(NC(CC1(O)Cc2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G04 compound treatment 699593.0 226000.0 0.47 696910.0 207000.0 0.45 0.6462 0.9998 1410432 ChemDiv1_021960 CCOC(=O)c1c(NC(=O)c2c(C)onc2c3ccccc3Cl)sc4CC(C)CCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G05 compound treatment 690651.0 217000.0 0.45 719250.0 229000.0 0.5 0.6673 0.9986 1980231 ChemDiv1_021961 CCOc1ccccc1NC(=O)c2cc(ccc2N3CCN(CC3)C(c4ccccc4)c5ccccc5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G06 compound treatment 707512.0 234000.0 0.48 671449.0 182000.0 0.39 0.6188 0.9949 1597830 ChemDiv1_021962 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4nccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G07 compound treatment 694544.0 221000.0 0.46 706978.0 217000.0 0.47 0.6542 0.9999 1216635 ChemDiv1_021963 COc1cc(cc(OC)c1OC)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G08 compound treatment 728188.0 254000.0 0.52 722405.0 233000.0 0.5 0.7269 0.9998 1270383 ChemDiv1_021964 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G09 compound treatment 746536.0 273000.0 0.56 750827.0 261000.0 0.56 0.7972 1.0 1487802 ChemDiv1_021965 COc1ccc(cc1)N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G10 compound treatment 740521.0 267000.0 0.55 713054.0 223000.0 0.48 0.7306 0.9979 1679531 ChemDiv1_021966 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3Cl)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G11 compound treatment 734121.0 260000.0 0.54 727184.0 237000.0 0.51 0.7429 0.9998 1980232 ChemDiv1_021967 COc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc(Sc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G12 compound treatment 694014.0 220000.0 0.45 715502.0 226000.0 0.49 0.6665 0.9993 1625835 ChemDiv1_021968 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G13 compound treatment 740116.0 266000.0 0.55 752847.0 263000.0 0.57 0.7909 0.9998 1980233 ChemDiv1_021969 COc1ccc(cc1OC)c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G14 compound treatment 747142.0 273000.0 0.56 715644.0 226000.0 0.49 0.7442 0.9975 1980234 ChemDiv1_021970 c1ccc(cc1)c2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G15 compound treatment 747866.0 274000.0 0.57 754938.0 265000.0 0.57 0.8054 1.0 1667218 ChemDiv1_021971 CCCCn1c(=O)nc2n(c3cccc(Cl)c3)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G16 compound treatment 751395.0 277000.0 0.57 723434.0 234000.0 0.51 0.7624 0.9981 1980235 ChemDiv1_021972 C/C(=N\OCc1nc2c3c(c(oc3ncn2n1)c4ccccc4)c5ccccc5)/c6cccs6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G17 compound treatment 764404.0 290000.0 0.6 764714.0 275000.0 0.59 0.8445 1.0 1624328 ChemDiv1_021973 Cc1cccc(c1)n2c3cccc(Cl)c3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G18 compound treatment 724362.0 250000.0 0.52 699172.0 209000.0 0.45 0.6858 0.9978 1980236 ChemDiv1_021974 COc1ccc(/C=C(\NC(=O)c2ccc(C)cc2)/C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G19 compound treatment 755760.0 282000.0 0.58 722011.0 232000.0 0.5 0.7666 0.9973 1382583 ChemDiv1_021975 CN1C(=O)N(C)C2(N(C)C(=O)N(C)C12c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G20 compound treatment 722080.0 248000.0 0.51 706693.0 217000.0 0.47 0.694 0.9991 1980237 ChemDiv1_021976 Cc1c(NC(=O)/C(=C/c2ccc(cc2)C(C)(C)C)/C#N)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G21 compound treatment 693126.0 219000.0 0.45 764356.0 274000.0 0.59 0.74 0.9909 1980238 ChemDiv1_021977 Cc1c(/N=C/c2ccc(OC(=O)/C=C/c3ccc(Cl)cc3)cc2)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G22 compound treatment 713665.0 240000.0 0.49 750681.0 261000.0 0.56 0.749 0.9978 1702059 ChemDiv1_021978 Oc1c(Br)cc2oc3CCCCc3c2c1CNc4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G23 mock treatment 714379.0 240000.0 0.5 744823.0 255000.0 0.55 0.7411 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 G24 mock treatment 237246.0 -237000.0 -0.49 241487.0 -248000.0 -0.54 -0.7257 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H01 compound treatment 664135.0 190000.0 0.39 611941.0 122000.0 0.26 0.4644 0.9815 1729961 ChemDiv1_021979 CC(C)C(=O)Nc1sc2CCCc2c1C(=O)Nc3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H02 compound treatment 690172.0 216000.0 0.45 639182.0 149000.0 0.32 0.5441 0.9875 1980239 ChemDiv1_021980 O=C(CN1C2=NCCN2c3ccccc13)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H03 compound treatment 700101.0 226000.0 0.47 645975.0 156000.0 0.34 0.569 0.9874 1294086 ChemDiv1_021981 COc1cccc(C2Nc3cccc4cccc(N2)c34)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H04 compound treatment 746211.0 272000.0 0.56 658283.0 168000.0 0.36 0.6551 0.9781 1980240 ChemDiv1_021982 Cc1ccc(C)c(c1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H05 compound treatment 736873.0 263000.0 0.54 654018.0 164000.0 0.36 0.6349 0.9789 1500960 ChemDiv1_021983 COc1cc(cc(OC)c1OC(=O)C)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H06 compound treatment 733886.0 260000.0 0.54 618379.0 129000.0 0.28 0.576 0.9532 1313897 ChemDiv1_021984 O=C(COc1ccccc1)Nc2sc3CCCc3c2C(=O)Nc4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H07 compound treatment 731921.0 258000.0 0.53 636504.0 147000.0 0.32 0.6009 0.9695 1714558 ChemDiv1_021985 Oc1ccc(C2Nc3cccc4cccc(N2)c34)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H08 compound treatment 740639.0 267000.0 0.55 676083.0 186000.0 0.4 0.6742 0.9883 1204660 ChemDiv1_021986 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H09 compound treatment 798923.0 325000.0 0.67 701801.0 212000.0 0.46 0.7986 0.9828 1472236 ChemDiv1_021987 CCN(CC)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H10 compound treatment 744927.0 271000.0 0.56 711425.0 222000.0 0.48 0.7346 0.9971 1415804 ChemDiv1_021988 Cc1cccc(NC(=O)c2c(NC(=O)c3ccccc3)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H11 compound treatment 756578.0 283000.0 0.58 697651.0 208000.0 0.45 0.7305 0.9917 1927653 ChemDiv1_021989 COc1ccc(cc1Br)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H12 compound treatment 727551.0 254000.0 0.52 709442.0 220000.0 0.48 0.7062 0.9988 1260605 ChemDiv1_021990 Brc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H13 compound treatment 744014.0 270000.0 0.56 715146.0 225000.0 0.49 0.7389 0.9978 1980241 ChemDiv1_021991 Nc1ccc(cc1)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H14 compound treatment 739402.0 265000.0 0.55 696981.0 207000.0 0.45 0.7044 0.995 1463368 ChemDiv1_021992 COc1ccccc1NC(=O)c2c(NC(=O)C(C)(C)C)sc3CCCc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H15 compound treatment 759651.0 286000.0 0.59 741180.0 251000.0 0.54 0.8016 0.9992 1577329 ChemDiv1_021993 CCN(CC)CC(O)Cn1c(c(c2ccccc2)c3ccc4ccccc4c13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H16 compound treatment 722984.0 249000.0 0.51 688238.0 198000.0 0.43 0.667 0.996 1734535 ChemDiv1_021994 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H17 compound treatment 724487.0 250000.0 0.52 731095.0 241000.0 0.52 0.7348 1.0 1980242 ChemDiv1_021995 Cc1cc(C)c2n(CC(O)Cn3cnc(c3c4ccccc4)c5ccccc5)c(c(c6ccccc6)c2c1)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H18 compound treatment 720302.0 246000.0 0.51 668830.0 179000.0 0.39 0.6334 0.991 1980243 ChemDiv1_021996 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5ccccc5Br)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H19 compound treatment 780559.0 307000.0 0.63 715109.0 225000.0 0.49 0.7922 0.9917 1980244 ChemDiv1_021997 CCOC(=O)C1=C(N)Oc2ccc3ccccc3c2C1c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H20 compound treatment 687856.0 214000.0 0.44 698960.0 209000.0 0.45 0.6322 0.9999 1980245 ChemDiv1_021998 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4[N+](=O)[O-])c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H21 compound treatment 740554.0 267000.0 0.55 671711.0 182000.0 0.39 0.6674 0.9865 1980246 ChemDiv1_021999 C=CCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H22 compound treatment 715740.0 242000.0 0.5 693500.0 204000.0 0.44 0.6645 0.9981 1980247 ChemDiv1_022000 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4OCC=C)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H23 mock treatment 726763.0 253000.0 0.52 707684.0 218000.0 0.47 0.7023 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 H24 mock treatment 224711.0 -249000.0 -0.51 251958.0 -238000.0 -0.51 -0.728 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I01 compound treatment 652152.0 178000.0 0.37 610085.0 120000.0 0.26 0.444 0.9857 1671535 ChemDiv1_022001 CC1C(O)CC(NC1c2ccc(C)cc2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I02 compound treatment 709479.0 235000.0 0.49 658817.0 169000.0 0.37 0.6023 0.9902 1980248 ChemDiv1_022002 CC(=O)c1c(C)nc2c(C#N)c(C)n(c3ccccc3)c2c1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I03 compound treatment 713306.0 239000.0 0.49 716096.0 226000.0 0.49 0.6955 1.0 1546646 ChemDiv1_022003 OC(=O)c1ccc(cc1Cl)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I04 compound treatment 723461.0 249000.0 0.51 690587.0 201000.0 0.43 0.6713 0.9964 1565975 ChemDiv1_022004 COc1ccc(C=c2sc3nc(=O)cnn3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I05 compound treatment 767553.0 294000.0 0.61 705887.0 216000.0 0.47 0.7591 0.9918 1399684 ChemDiv1_022005 CN1CCN(CC1)c2ccc(Nc3ccnc4cc(Cl)ccc34)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I06 compound treatment 763872.0 290000.0 0.6 695760.0 206000.0 0.45 0.7382 0.9895 1530032 ChemDiv1_022006 OC1=C(C(N(C1=O)c2nccs2)c3ccc(Cl)cc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I07 compound treatment 824534.0 351000.0 0.72 736372.0 247000.0 0.53 0.8889 0.9888 1346420 ChemDiv1_022007 O=C1NC(Nc2sc3CCCCc3c12)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I08 compound treatment 731128.0 257000.0 0.53 733959.0 244000.0 0.53 0.7489 1.0 1353908 ChemDiv1_022008 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I09 compound treatment 818020.0 344000.0 0.71 733044.0 243000.0 0.53 0.8743 0.9891 1604505 ChemDiv1_022009 COc1cc(OC)cc(c1)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I10 compound treatment 726763.0 253000.0 0.52 724525.0 235000.0 0.51 0.7281 0.9999 1597197 ChemDiv1_022010 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I11 compound treatment 736131.0 262000.0 0.54 758964.0 269000.0 0.58 0.7945 0.9993 1639392 ChemDiv1_022011 CSc1ccc(cc1)c2nc(c([nH]2)c3ccccc3Br)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I12 compound treatment 714527.0 241000.0 0.5 715841.0 226000.0 0.49 0.6969 1.0 1463101 ChemDiv1_022012 Clc1ccc(OCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I13 compound treatment 756323.0 282000.0 0.58 731556.0 242000.0 0.52 0.782 0.9985 1980249 ChemDiv1_022013 Clc1c2ccccc2c(c3nc(c([nH]3)c4ccccc4)c5ccc6sc7ccccc7c6c5)c8ccccc18 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I14 compound treatment 717518.0 244000.0 0.5 738153.0 248000.0 0.54 0.7355 0.9994 1980250 ChemDiv1_022014 Brc1ccccc1c2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I15 compound treatment 756406.0 282000.0 0.58 766450.0 277000.0 0.6 0.8355 0.9999 1710871 ChemDiv1_022015 CCCCn1c(=O)nc2n(c3ccc(Cl)cc3)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I16 compound treatment 747494.0 273000.0 0.56 752091.0 262000.0 0.57 0.8005 1.0 1980251 ChemDiv1_022016 C/C(=N\OCC(=O)Nc1oc(c(c1C#N)c2ccccc2)c3ccccc3)/c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I17 compound treatment 751460.0 277000.0 0.57 779991.0 290000.0 0.63 0.849 0.9989 1660476 ChemDiv1_022017 Cc1ccc(cc1C)n2c3cccc(Cl)c3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I18 compound treatment 709353.0 235000.0 0.49 711529.0 222000.0 0.48 0.6828 1.0 1980252 ChemDiv1_022018 Cc1c(NC(=O)/C(=C/c2ccc(F)cc2)/NC(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I19 compound treatment 704342.0 230000.0 0.48 738135.0 248000.0 0.54 0.7162 0.9981 1503984 ChemDiv1_022019 CCC(C)C(N1C2NC(=O)NC2NC1=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I20 compound treatment 691850.0 218000.0 0.45 708197.0 218000.0 0.47 0.6521 0.9997 1980253 ChemDiv1_022020 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I21 compound treatment 730033.0 256000.0 0.53 722740.0 233000.0 0.5 0.7301 0.9997 1980254 ChemDiv1_022021 Clc1ccccc1C=c2sc3nc(nn3c2=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I22 compound treatment 700934.0 227000.0 0.47 756785.0 267000.0 0.58 0.7398 0.9946 1272453 ChemDiv1_022022 Cc1ccc(C)c(NCc2c(O)c(Br)cc3oc4CCCCc4c23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I23 mock treatment 711901.0 238000.0 0.49 723288.0 233000.0 0.51 0.7045 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 I24 mock treatment 211255.0 -263000.0 -0.54 268305.0 -222000.0 -0.48 -0.7226 -0.9981 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J01 compound treatment 693460.0 219000.0 0.45 604899.0 115000.0 0.25 0.4964 0.9603 1980255 ChemDiv1_022023 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J02 compound treatment 694744.0 221000.0 0.46 640977.0 151000.0 0.33 0.5535 0.9868 1980256 ChemDiv1_022024 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J03 compound treatment 702133.0 228000.0 0.47 695359.0 206000.0 0.44 0.6475 0.9996 1279714 ChemDiv1_022025 COc1ccc(OC)c(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J04 compound treatment 743275.0 269000.0 0.56 662521.0 173000.0 0.37 0.6573 0.9813 1980257 ChemDiv1_022026 Clc1ccc(cc1Cl)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J05 compound treatment 746511.0 273000.0 0.56 700071.0 210000.0 0.45 0.7195 0.9945 1717343 ChemDiv1_022027 Brc1ccccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J06 compound treatment 674920.0 201000.0 0.41 679927.0 190000.0 0.41 0.5842 1.0 1242059 ChemDiv1_022028 CC(C)(C)C(=O)Nc1sc2CCCc2c1C(=O)Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J07 compound treatment 650614.0 177000.0 0.36 683558.0 194000.0 0.42 0.5542 0.9976 1048072 ChemDiv1_022029 Brc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J08 compound treatment 759621.0 286000.0 0.59 701134.0 211000.0 0.46 0.7403 0.9921 1128078 ChemDiv1_022030 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J09 compound treatment 697283.0 223000.0 0.46 723352.0 233000.0 0.51 0.6833 0.9989 1147205 ChemDiv1_022031 COc1ccccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J10 compound treatment 719105.0 245000.0 0.51 717917.0 228000.0 0.49 0.7068 0.9999 1487584 ChemDiv1_022032 Brc1ccc(NC(=O)c2c(NC(=O)c3cccnc3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J11 compound treatment 734037.0 260000.0 0.54 712843.0 223000.0 0.48 0.7208 0.9986 1927921 ChemDiv1_022033 Fc1ccc(Br)cc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J12 compound treatment 750704.0 277000.0 0.57 724166.0 234000.0 0.51 0.7625 0.9982 1162535 ChemDiv1_022034 Cc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3Br)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J13 compound treatment 789247.0 315000.0 0.65 711891.0 222000.0 0.48 0.8 0.9889 1364638 ChemDiv1_022035 Oc1ccc(NC(=O)CN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J14 compound treatment 754006.0 280000.0 0.58 695204.0 205000.0 0.44 0.723 0.9916 1144619 ChemDiv1_022036 CCOc1ccccc1NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc4CCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J15 compound treatment 744869.0 271000.0 0.56 764701.0 275000.0 0.59 0.816 0.9995 1980258 ChemDiv1_022037 CC1CCN(CC(O)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J16 compound treatment 700798.0 227000.0 0.47 705103.0 215000.0 0.47 0.6605 1.0 1229314 ChemDiv1_022038 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccc(C)cc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J17 compound treatment 757664.0 284000.0 0.59 752096.0 262000.0 0.57 0.8154 0.9999 1721141 ChemDiv1_022039 Cc1nn(CC(O)Cn2c(c(c3ccccc3)c4cc(C)cc(C)c24)c5ccccc5)c(C)c1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J18 compound treatment 729289.0 255000.0 0.53 735704.0 246000.0 0.53 0.7489 1.0 1934604 ChemDiv1_022040 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5ccccc5F)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J19 compound treatment 695103.0 221000.0 0.46 643902.0 154000.0 0.33 0.5585 0.9881 1716477 ChemDiv1_022041 CCOC(=O)C1=C(N)Oc2ccc3ccccc3c2C1c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J20 compound treatment 729074.0 255000.0 0.53 724373.0 235000.0 0.51 0.7312 0.9998 1980259 ChemDiv1_022042 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cccc(c4)[N+](=O)[O-])c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J21 compound treatment 693934.0 220000.0 0.45 732772.0 243000.0 0.53 0.6928 0.9973 1937281 ChemDiv1_022043 C(N1C2=NCCN2c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J22 compound treatment 695174.0 221000.0 0.46 709990.0 220000.0 0.48 0.6597 0.9998 1944349 ChemDiv1_022044 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OCC=C)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J23 mock treatment 732328.0 258000.0 0.53 729708.0 240000.0 0.52 0.7441 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 J24 mock treatment 226408.0 -248000.0 -0.51 229172.0 -261000.0 -0.56 -0.7604 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K01 compound treatment 676610.0 203000.0 0.42 611642.0 122000.0 0.26 0.4821 0.9752 1460373 ChemDiv1_022045 CCCC1C(NC(CC1(O)c2ccc(F)cc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K02 compound treatment 696885.0 223000.0 0.46 648864.0 159000.0 0.34 0.5687 0.9898 1980260 ChemDiv1_022046 O=C(C[N+]1(CCC2CC1)CC2=O)N3c4ccccc4Sc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K03 compound treatment 624070.0 150000.0 0.31 633156.0 143000.0 0.31 0.4384 1.0 1296018 ChemDiv1_022047 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)cc3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K04 compound treatment 705320.0 231000.0 0.48 714146.0 224000.0 0.49 0.6809 1.0 1120335 ChemDiv1_022048 Clc1ccccc1C=c2sc3nc(=O)c(Cc4ccccc4)nn3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K05 compound treatment 714611.0 241000.0 0.5 696453.0 207000.0 0.45 0.6674 0.9986 1980261 ChemDiv1_022049 CCOC(=O)C1CCN(CC1)c2ccc(cc2C(=O)Nc3cc(OC)cc4cccnc34)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K06 compound treatment 673666.0 200000.0 0.41 711576.0 222000.0 0.48 0.6308 0.9971 1273182 ChemDiv1_022050 OC1=C(C(N(C1=O)c2nccs2)c3ccc(F)cc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K07 compound treatment 751131.0 277000.0 0.57 658031.0 168000.0 0.36 0.6619 0.9762 1643251 ChemDiv1_022051 Fc1ccccc1C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K08 compound treatment 734580.0 261000.0 0.54 709875.0 220000.0 0.48 0.7171 0.9982 1515403 ChemDiv1_022052 COc1cc(ccc1O)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K09 compound treatment 738384.0 264000.0 0.55 725598.0 236000.0 0.51 0.7467 0.9994 1980262 ChemDiv1_022053 Fc1ccc(cc1)C(=O)c2ccc(cc2)c3nc4cc5ccccc5cc4nc3c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K10 compound treatment 699660.0 226000.0 0.47 722724.0 233000.0 0.5 0.6858 0.9992 1179201 ChemDiv1_022054 CC(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K11 compound treatment 750010.0 276000.0 0.57 744933.0 255000.0 0.55 0.7933 0.9999 1980263 ChemDiv1_022055 Fc1ccccc1c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K12 compound treatment 710701.0 237000.0 0.49 676240.0 186000.0 0.4 0.6307 0.9955 1678832 ChemDiv1_022056 CC(C)c1ccc(C)cc1OCC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K13 compound treatment 743092.0 269000.0 0.56 712958.0 223000.0 0.48 0.7342 0.9976 1980264 ChemDiv1_022057 C(Oc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K14 compound treatment 705923.0 232000.0 0.48 707771.0 218000.0 0.47 0.672 1.0 1980265 ChemDiv1_022058 Clc1ccc(OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K15 compound treatment 688473.0 214000.0 0.44 725714.0 236000.0 0.51 0.674 0.9975 1980266 ChemDiv1_022059 CCCCn1c(=O)nc2n(c3ccc(cc3)[N+](=O)[O-])c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K16 compound treatment 732372.0 258000.0 0.53 703013.0 213000.0 0.46 0.7034 0.9974 1980267 ChemDiv1_022060 COc1ccc(cc1OC)/C(=N/OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6)/C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K17 compound treatment 760519.0 287000.0 0.59 749532.0 260000.0 0.56 0.8156 0.9997 1145396 ChemDiv1_022061 Fc1ccc(cc1)n2c3cccc(Cl)c3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K18 compound treatment 693625.0 220000.0 0.45 723797.0 234000.0 0.51 0.6786 0.9985 1980268 ChemDiv1_022062 Brc1ccc(cc1)c2nn(cc2/C=C(\NC(=O)c3ccccc3)/C(=O)NCCc4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K19 compound treatment 703382.0 229000.0 0.47 729565.0 240000.0 0.52 0.7017 0.999 1980269 ChemDiv1_022063 CN1C(NC(=O)NC(C)(C)CO)C(NC(=O)NC(C)(C)CO)N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K20 compound treatment 1017735.0 544000.0 1.12 1013428.0 524000.0 1.13 1.595 1.0 1980270 ChemDiv1_022064 CN(C)c1ccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K21 compound treatment 746771.0 273000.0 0.56 719701.0 230000.0 0.5 0.7499 0.9981 1980271 ChemDiv1_022065 Cc1ccc(cc1)C(=O)N/C(=C\c2ccc(Cl)cc2)/C(=O)NCCCn3ccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K22 compound treatment 659713.0 186000.0 0.38 720491.0 231000.0 0.5 0.624 0.9915 1616045 ChemDiv1_022066 Oc1c(I)cc2oc3CCCCc3c2c1CNc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K23 mock treatment 734439.0 260000.0 0.54 718741.0 229000.0 0.5 0.7304 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 K24 mock treatment 243236.0 -231000.0 -0.48 220481.0 -269000.0 -0.58 -0.7491 -0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L01 compound treatment 665734.0 192000.0 0.4 577201.0 87300.0 0.19 0.4135 0.9428 1048960 ChemDiv1_022067 Brc1cccc(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L02 compound treatment 718751.0 245000.0 0.51 644134.0 154000.0 0.33 0.5934 0.9798 1980272 ChemDiv1_022068 CC(=O)CN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L03 compound treatment 679181.0 205000.0 0.42 647263.0 157000.0 0.34 0.5404 0.9942 1334209 ChemDiv1_022069 Oc1cccc(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L04 compound treatment 693072.0 219000.0 0.45 663354.0 173000.0 0.38 0.5853 0.9957 1980273 ChemDiv1_022070 O=C(CN1C2=NCCCN2c3ccccc13)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L05 compound treatment 770445.0 296000.0 0.61 736446.0 247000.0 0.53 0.8101 0.9977 1350864 ChemDiv1_022071 CCN(CC)c1ccc(C2Nc3cccc4cccc(N2)c34)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L06 compound treatment 705835.0 232000.0 0.48 669205.0 179000.0 0.39 0.6129 0.9946 1408136 ChemDiv1_022072 COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc4CCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L07 compound treatment 726079.0 252000.0 0.52 697681.0 208000.0 0.45 0.686 0.9974 1435784 ChemDiv1_022073 Oc1c(CC=C)cccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L08 compound treatment 706099.0 232000.0 0.48 692773.0 203000.0 0.44 0.6493 0.9991 1310887 ChemDiv1_022074 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L09 compound treatment 756311.0 282000.0 0.58 848061.0 358000.0 0.78 0.9603 0.9901 1244500 ChemDiv1_022075 CCOc1ccc(cc1OC)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L10 compound treatment 734288.0 260000.0 0.54 729410.0 240000.0 0.52 0.7466 0.9998 1455973 ChemDiv1_022076 Cc1cccc(NC(=O)c2c(NC(=O)c3ccccc3Cl)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L11 compound treatment 729239.0 255000.0 0.53 728281.0 238000.0 0.52 0.7375 0.9999 1605354 ChemDiv1_022077 N1C(Nc2cccc3cccc1c23)c4ccc(cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L12 compound treatment 729123.0 255000.0 0.53 666617.0 177000.0 0.38 0.6429 0.9877 1684969 ChemDiv1_022078 Cc1cccc(NC(=O)c2c(NC(=O)c3ccccc3C)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L13 compound treatment 746160.0 272000.0 0.56 695439.0 206000.0 0.44 0.7119 0.9933 1980274 ChemDiv1_022079 FC(F)(F)c1cccc(NC(=O)CN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L14 compound treatment 774452.0 300000.0 0.62 703207.0 213000.0 0.46 0.7651 0.9894 1743247 ChemDiv1_022080 CCc1ccccc1NC(=O)c2c(NC(=O)C(C)(C)C)sc3CCCc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L15 compound treatment 728678.0 255000.0 0.53 746338.0 256000.0 0.56 0.7643 0.9996 1980275 ChemDiv1_022081 OC(CN(CC=C)CC=C)Cn1c(c(c2ccccc2)c3ccc4ccccc4c13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L16 compound treatment 750863.0 277000.0 0.57 712991.0 223000.0 0.48 0.7456 0.9965 1469723 ChemDiv1_022082 CCOc1ccccc1NC(=O)c2c(NC(=O)c3cccc(C)c3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L17 compound treatment 711555.0 238000.0 0.49 703008.0 213000.0 0.46 0.673 0.9995 1203511 ChemDiv1_022083 Cc1cc(C)n(CC(O)Cn2c(c(c3ccccc3)c4cc(C)cc(C)c24)c5ccccc5)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L18 compound treatment 723651.0 250000.0 0.52 716915.0 227000.0 0.49 0.7119 0.9997 1980276 ChemDiv1_022084 CCOc1cc(ccc1OC(=O)c2ccccc2Cl)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L19 compound treatment 728238.0 254000.0 0.52 680872.0 191000.0 0.41 0.6634 0.993 1932173 ChemDiv1_022085 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L20 compound treatment 718158.0 244000.0 0.5 685164.0 195000.0 0.42 0.6553 0.9962 1980277 ChemDiv1_022086 CN(C)c1ccc(cc1)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L21 compound treatment 739674.0 266000.0 0.55 722476.0 233000.0 0.5 0.7438 0.9991 1980278 ChemDiv1_022087 Clc1ccccc1CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L22 compound treatment 707331.0 233000.0 0.48 673949.0 184000.0 0.4 0.6223 0.9956 1980279 ChemDiv1_022088 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4OCc5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L23 mock treatment 724792.0 251000.0 0.52 710132.0 220000.0 0.48 0.7032 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 L24 mock treatment 277719.0 -196000.0 -0.41 217507.0 -272000.0 -0.59 -0.7033 -0.9833 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M01 compound treatment 684096.0 210000.0 0.43 616980.0 127000.0 0.28 0.5012 0.9759 1216559 ChemDiv1_022089 CCCC1C(NC(C(C)C1(C)O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M02 compound treatment 672634.0 199000.0 0.41 655025.0 165000.0 0.36 0.5427 0.9977 1980280 ChemDiv1_022090 [O-][N+](=O)c1ccc(cc1)n2c(=N)c(C#N)cc3[nH]c4ccccc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M03 compound treatment 615654.0 142000.0 0.29 653739.0 164000.0 0.35 0.4576 0.9954 1720619 ChemDiv1_022091 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccccc4)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M04 compound treatment 682384.0 208000.0 0.43 674721.0 185000.0 0.4 0.5871 0.9993 1565279 ChemDiv1_022092 COc1ccc(C=c2sc3nc(=O)c(Cc4ccccc4)nn3c2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M05 compound treatment 736547.0 263000.0 0.54 738209.0 248000.0 0.54 0.7633 1.0 1980281 ChemDiv1_022093 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3c(OC)ccc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M06 compound treatment 701719.0 228000.0 0.47 674368.0 185000.0 0.4 0.6148 0.9967 1683432 ChemDiv1_022094 OC1=C(C(N(C1=O)c2nccs2)c3ccccc3Cl)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M07 compound treatment 715268.0 241000.0 0.5 692207.0 202000.0 0.44 0.6619 0.9979 1200563 ChemDiv1_022095 COc1ccc(OC)c(c1)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M08 compound treatment 686143.0 212000.0 0.44 686286.0 196000.0 0.43 0.6103 0.9999 1135002 ChemDiv1_022096 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(F)cc3)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M09 compound treatment 713881.0 240000.0 0.5 704521.0 215000.0 0.46 0.6787 0.9995 1477799 ChemDiv1_022097 Fc1ccc(cc1)C(=O)c2ccc(cc2)c3nc4ccccc4nc3c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M10 compound treatment 705434.0 231000.0 0.48 700853.0 211000.0 0.46 0.6607 0.9997 1471315 ChemDiv1_022098 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(cc3)C(C)(C)C)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M11 compound treatment 718350.0 244000.0 0.5 693675.0 204000.0 0.44 0.6686 0.9978 1980282 ChemDiv1_022099 Fc1ccccc1c2nc(c([nH]2)c3ccc(Sc4ccccc4)cc3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M12 compound treatment 700726.0 227000.0 0.47 672976.0 183000.0 0.4 0.6112 0.9966 1273002 ChemDiv1_022100 COc1ccc(CC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M13 compound treatment 731978.0 258000.0 0.53 687287.0 197000.0 0.43 0.6787 0.994 1714571 ChemDiv1_022101 Cc1ccc(C)c(c1)c2nc3ccccc3nc2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M14 compound treatment 710549.0 237000.0 0.49 699005.0 209000.0 0.45 0.6654 0.9993 1980283 ChemDiv1_022102 Cc1ccc(OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M15 compound treatment 724950.0 251000.0 0.52 700559.0 211000.0 0.46 0.6888 0.998 1157061 ChemDiv1_022103 CCCCn1c(=O)nc2n(c3ccc(OC)cc3)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M16 compound treatment 700223.0 226000.0 0.47 694754.0 205000.0 0.44 0.6438 0.9997 1980284 ChemDiv1_022104 C/C(=N\OCc1nc2c3c(c(oc3ncn2n1)c4ccccc4)c5ccccc5)/c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M17 compound treatment 688311.0 214000.0 0.44 731605.0 242000.0 0.52 0.6828 0.9965 1119757 ChemDiv1_022105 Clc1ccc(cc1Cl)n2c3cccc(Cl)c3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M18 compound treatment 699640.0 226000.0 0.47 704532.0 215000.0 0.46 0.6579 1.0 1980285 ChemDiv1_022106 CN(C)CCCNC(=O)/C(=C/c1cn(nc1c2ccc(Br)cc2)c3ccccc3)/NC(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M19 compound treatment 693580.0 220000.0 0.45 735166.0 245000.0 0.53 0.6959 0.9969 1947079 ChemDiv1_022107 CCCCNC(=O)NC1C(NC(=O)NCCCC)N(C)C(=O)N1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M20 compound treatment 665683.0 192000.0 0.4 718366.0 229000.0 0.49 0.6295 0.9939 1980286 ChemDiv1_022108 Cc1ccc(cc1)c2nc3sc(=Cc4ccco4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M21 compound treatment 683771.0 210000.0 0.43 718671.0 229000.0 0.5 0.6564 0.9978 1980287 ChemDiv1_022109 Clc1ccc(/C=C/C(=O)NCCCn2ccnc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M22 compound treatment 711607.0 238000.0 0.49 712706.0 223000.0 0.48 0.6879 1.0 1729797 ChemDiv1_022110 Oc1ccccc1CN2CCN(Cc3ccccc3O)C2c4c(O)ccc5oc6CCCCc6c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M23 mock treatment 708796.0 235000.0 0.48 680190.0 190000.0 0.41 0.634 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 M24 mock treatment 205705.0 -268000.0 -0.55 363356.0 -127000.0 -0.27 -0.5852 -0.9472 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N01 compound treatment 672948.0 199000.0 0.41 628688.0 139000.0 0.3 0.5029 0.9882 1242012 ChemDiv1_022111 CCOc1cccc(C2Nc3cccc4cccc(N2)c34)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N02 compound treatment 695634.0 222000.0 0.46 659213.0 169000.0 0.37 0.5827 0.994 1947398 ChemDiv1_022112 CC(C)(C)C(=O)CN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N03 compound treatment 708140.0 234000.0 0.48 673182.0 183000.0 0.4 0.6223 0.9952 1333912 ChemDiv1_022113 Oc1ccc(Br)cc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N04 compound treatment 733529.0 260000.0 0.54 650741.0 161000.0 0.35 0.625 0.9782 1980288 ChemDiv1_022114 O=C(CN1C2=NCCCN2c3ccccc13)c4ccc(cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N05 compound treatment 754932.0 281000.0 0.58 671417.0 182000.0 0.39 0.6879 0.982 1293812 ChemDiv1_022115 N1C(Nc2cccc3cccc1c23)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N06 compound treatment 714009.0 240000.0 0.5 650219.0 160000.0 0.35 0.5958 0.9848 1119159 ChemDiv1_022116 Clc1ccc(OCC(=O)Nc2sc3CCCc3c2C(=O)Nc4cccc5ccccc45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N07 compound treatment 697888.0 224000.0 0.46 683946.0 194000.0 0.42 0.6238 0.9989 1430468 ChemDiv1_022117 Clc1ccccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N08 compound treatment 733446.0 259000.0 0.54 691869.0 202000.0 0.44 0.6879 0.9949 1980289 ChemDiv1_022118 CCOc1ccc(NC(=O)c2c(NC(=O)C(F)(F)F)sc3CCCc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N09 compound treatment 684076.0 210000.0 0.43 699522.0 210000.0 0.45 0.6275 0.9997 1576690 ChemDiv1_022119 COc1cc(ccc1OC(=O)C)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N10 compound treatment 699431.0 225000.0 0.47 691260.0 201000.0 0.44 0.6373 0.9995 1625866 ChemDiv1_022120 Clc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N11 compound treatment 721148.0 247000.0 0.51 677812.0 188000.0 0.41 0.6484 0.9937 1218514 ChemDiv1_022121 Cc1cccc(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N12 compound treatment 696147.0 222000.0 0.46 667632.0 178000.0 0.38 0.5963 0.9962 1510558 ChemDiv1_022122 Cc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N13 compound treatment 673164.0 199000.0 0.41 680267.0 190000.0 0.41 0.5821 1.0 1670068 ChemDiv1_022123 C1C(Nc2ccccc2N=C1c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N14 compound treatment 710889.0 237000.0 0.49 665174.0 175000.0 0.38 0.6141 0.9921 1170526 ChemDiv1_022124 CCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N15 compound treatment 811747.0 338000.0 0.7 725817.0 236000.0 0.51 0.8541 0.9883 1980290 ChemDiv1_022125 OC(CN1CCCCCC1)Cn2c(c(c3ccccc3)c4ccc5ccccc5c24)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N16 compound treatment 714950.0 241000.0 0.5 692301.0 202000.0 0.44 0.6615 0.998 1980291 ChemDiv1_022126 COc1cc(ccc1OCc2ccccc2)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N17 compound treatment 722437.0 248000.0 0.51 719202.0 229000.0 0.5 0.7136 0.9999 1346597 ChemDiv1_022127 Cc1cc(C)c2n(CC(O)Cn3nnc4ccccc34)c(c(c5ccccc5)c2c1)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N18 compound treatment 730724.0 257000.0 0.53 693351.0 203000.0 0.44 0.6862 0.9958 1951757 ChemDiv1_022128 COc1cc(cc(OC)c1OC)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N19 compound treatment 759897.0 286000.0 0.59 716563.0 227000.0 0.49 0.7643 0.9958 1932194 ChemDiv1_022129 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N20 compound treatment 708723.0 235000.0 0.48 703556.0 214000.0 0.46 0.6697 0.9997 1980292 ChemDiv1_022130 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cc(Br)ccc4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N21 compound treatment 732166.0 258000.0 0.53 707434.0 218000.0 0.47 0.7098 0.9981 1980293 ChemDiv1_022131 CC(C)(C)c1ccc(CN2C3=NCCN3c4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N22 compound treatment 707850.0 234000.0 0.48 690439.0 201000.0 0.43 0.6483 0.9986 1980294 ChemDiv1_022132 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OCc5ccccc5Cl)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N23 mock treatment 704614.0 231000.0 0.48 672306.0 182000.0 0.39 0.6158 0.9957 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 N24 mock treatment 246607.0 -227000.0 -0.47 340004.0 -150000.0 -0.32 -0.5613 -0.9837 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O01 compound treatment 679411.0 205000.0 0.42 615249.0 125000.0 0.27 0.4917 0.9768 1494714 ChemDiv1_022133 CC1C(NC(C(C)C1(C)O)c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O02 compound treatment 697379.0 223000.0 0.46 631622.0 142000.0 0.31 0.543 0.9804 1340403 ChemDiv1_022134 CC1CCN(Cc2c(O)ccc3c4CCCc4c(=O)oc23)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O03 compound treatment 720055.0 246000.0 0.51 650657.0 161000.0 0.35 0.6052 0.983 1533429 ChemDiv1_022135 CC1(C)CC(=O)C2=C(C1)N(CCO)C3=C(C2c4ccccc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O04 compound treatment 685710.0 212000.0 0.44 655875.0 166000.0 0.36 0.5631 0.9953 1250612 ChemDiv1_022136 OC1=C(C(N(C1=O)c2nncs2)c3ccccc3Cl)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O05 compound treatment 707435.0 233000.0 0.48 654474.0 165000.0 0.36 0.5927 0.989 1670511 ChemDiv1_022137 Fc1ccccc1C2CC(=O)Nc3c2ccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O06 compound treatment 701353.0 227000.0 0.47 650460.0 161000.0 0.35 0.5776 0.9891 1301805 ChemDiv1_022138 OC1=C(C(N(C1=O)c2nccs2)c3cccc(Br)c3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O07 compound treatment 655973.0 182000.0 0.38 681541.0 192000.0 0.41 0.559 0.9988 1713725 ChemDiv1_022139 O=C1NC(Nc2sc3CCCCc3c12)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O08 compound treatment 712764.0 239000.0 0.49 668519.0 179000.0 0.39 0.6219 0.9928 1280501 ChemDiv1_022140 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3Cl)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O09 compound treatment 719915.0 246000.0 0.51 671534.0 182000.0 0.39 0.637 0.992 1980295 ChemDiv1_022141 Clc1ccc(cc1)c2nc3ccccc3nc2c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O10 compound treatment 705980.0 232000.0 0.48 636643.0 147000.0 0.32 0.5633 0.9801 1326768 ChemDiv1_022142 Cc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O11 compound treatment 741027.0 267000.0 0.55 678445.0 189000.0 0.41 0.6784 0.9891 1980296 ChemDiv1_022143 Fc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc5sc6ccccc6c5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O12 compound treatment 709301.0 235000.0 0.49 659704.0 170000.0 0.37 0.6034 0.9906 1630943 ChemDiv1_022144 COc1ccc(CC(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O13 compound treatment 736097.0 262000.0 0.54 686125.0 196000.0 0.42 0.6829 0.9928 1783987 ChemDiv1_022145 COc1cccc(c2nc(c([nH]2)c3cc(ccc3C)[N+](=O)[O-])c4ccccc4)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O14 compound treatment 693954.0 220000.0 0.45 651888.0 162000.0 0.35 0.569 0.9919 1338322 ChemDiv1_022146 Cc1ccccc1OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O15 compound treatment 736878.0 263000.0 0.54 706202.0 216000.0 0.47 0.7148 0.9973 1980297 ChemDiv1_022147 CCCCOC(=O)c1ccc(cc1)n2c3ccccc3cc4c(=O)n(CCCC)c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O16 compound treatment 675647.0 202000.0 0.42 649624.0 160000.0 0.35 0.5388 0.9958 1980298 ChemDiv1_022148 Clc1ccccc1/C=N/OCc2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O17 compound treatment 707507.0 233000.0 0.48 698283.0 208000.0 0.45 0.6598 0.9995 1012478 ChemDiv1_022149 CN(C)Cc1cc(cc(c1O)C(C)(C)C)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O18 compound treatment 704547.0 231000.0 0.48 671847.0 182000.0 0.39 0.615 0.9956 1980299 ChemDiv1_022150 Brc1ccc(cc1)c2nn(cc2/C=C(\NC(=O)c3ccccc3)/C(=O)NCc4cccnc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O19 compound treatment 711109.0 237000.0 0.49 700573.0 211000.0 0.46 0.6686 0.9994 1709590 ChemDiv1_022151 OC(=O)CN1C2NC(=O)NC2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O20 compound treatment 687390.0 213000.0 0.44 715405.0 226000.0 0.49 0.6567 0.9987 1980300 ChemDiv1_022152 Cc1ccc(cc1)c2nc3sc(=Cc4ccc(o4)c5ccc(Br)cc5)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O21 compound treatment 742354.0 268000.0 0.55 707616.0 218000.0 0.47 0.725 0.9968 1245778 ChemDiv1_022153 CCOc1cc(C=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)ccc1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O22 compound treatment 769229.0 295000.0 0.61 810504.0 321000.0 0.69 0.9217 0.9979 1457974 ChemDiv1_022154 Oc1ccccc1CN2CCN(Cc3ccccc3O)C2c4c(O)c(Br)cc5oc6CCCCc6c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O23 mock treatment 713164.0 239000.0 0.49 651232.0 161000.0 0.35 0.5961 0.9856 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 O24 mock treatment 394813.0 -79200.0 -0.16 525436.0 35600.0 0.08 -0.0611 -0.3384 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P01 compound treatment 659321.0 185000.0 0.38 610973.0 121000.0 0.26 0.4559 0.983 1446804 ChemDiv1_022155 Fc1ccccc1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P02 compound treatment 704064.0 230000.0 0.47 605028.0 115000.0 0.25 0.5121 0.9547 1980301 ChemDiv1_022156 O=C(CN1C2=NCCCN2c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P03 compound treatment 718655.0 245000.0 0.51 627054.0 137000.0 0.3 0.5671 0.968 1526751 ChemDiv1_022157 Clc1cccc(Cl)c1C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P04 compound treatment 689442.0 215000.0 0.44 584840.0 95000.0 0.21 0.4598 0.9386 1980302 ChemDiv1_022158 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P05 compound treatment 691038.0 217000.0 0.45 588230.0 98400.0 0.21 0.4674 0.9422 1048073 ChemDiv1_022159 Oc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P06 compound treatment 688744.0 215000.0 0.44 630664.0 141000.0 0.3 0.5289 0.9833 1980303 ChemDiv1_022160 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=O)c3cc(cc(c3)[N+](=O)[O-])[N+](=O)[O-])sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P07 compound treatment 678870.0 205000.0 0.42 632960.0 143000.0 0.31 0.518 0.9883 1122761 ChemDiv1_022161 COc1ccc(cc1OC)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P08 compound treatment 700680.0 227000.0 0.47 630092.0 140000.0 0.3 0.5455 0.978 1980304 ChemDiv1_022162 FC(F)(F)C(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P09 compound treatment 694069.0 220000.0 0.45 599865.0 110000.0 0.24 0.4896 0.9546 1505117 ChemDiv1_022163 COc1cccc(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P10 compound treatment 703418.0 229000.0 0.47 590707.0 101000.0 0.22 0.4892 0.9382 1277005 ChemDiv1_022164 Cc1ccc(NC(=O)c2c(NC(=O)c3ccc(C)cc3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P11 compound treatment 686510.0 213000.0 0.44 607049.0 117000.0 0.25 0.4895 0.9661 1533371 ChemDiv1_022165 COc1cc(cc(OC)c1O)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P12 compound treatment 735217.0 261000.0 0.54 638936.0 149000.0 0.32 0.6094 0.9699 1948900 ChemDiv1_022166 Cc1ccc(NC(=O)c2c(NC(=O)C(F)(F)F)sc3CCCc23)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P13 compound treatment 662676.0 189000.0 0.39 613556.0 124000.0 0.27 0.4647 0.9833 1624006 ChemDiv1_022167 OC(CN(CC=C)CC=C)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P14 compound treatment 703540.0 230000.0 0.47 637977.0 148000.0 0.32 0.5617 0.9819 1265561 ChemDiv1_022168 CCOc1ccccc1NC(=O)c2c(NC(=O)C(C)Oc3cccc(Cl)c3)sc4CCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P15 compound treatment 660901.0 187000.0 0.39 622039.0 132000.0 0.29 0.4751 0.9892 1980305 ChemDiv1_022169 CN(CC(O)Cn1c(c(c2ccccc2)c3ccc4ccccc4c13)c5ccccc5)C6CCCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P16 compound treatment 721621.0 248000.0 0.51 659772.0 170000.0 0.37 0.6215 0.987 1980306 ChemDiv1_022170 COc1cc(ccc1OCc2ccccc2Cl)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P17 compound treatment 723744.0 250000.0 0.52 649025.0 159000.0 0.34 0.6081 0.9808 1980307 ChemDiv1_022171 Cc1ccc(NCC(O)Cn2c(c(c3ccccc3)c4cc(C)cc(C)c24)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P18 compound treatment 716724.0 243000.0 0.5 637522.0 148000.0 0.32 0.5803 0.9764 1980308 ChemDiv1_022172 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P19 compound treatment 718778.0 245000.0 0.51 640037.0 150000.0 0.33 0.5871 0.9772 1980309 ChemDiv1_022173 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P20 compound treatment 719116.0 245000.0 0.51 635386.0 146000.0 0.31 0.5805 0.974 1980310 ChemDiv1_022174 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cc(ccc4O)[N+](=O)[O-])c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P21 compound treatment 788113.0 314000.0 0.65 656866.0 167000.0 0.36 0.7141 0.9619 1980311 ChemDiv1_022175 O=C(CN1C2=NCCN2c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P22 compound treatment 701255.0 227000.0 0.47 639838.0 150000.0 0.32 0.5612 0.9838 1980312 ChemDiv1_022176 CCOc1cc(ccc1OC)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P23 mock treatment 708635.0 235000.0 0.48 633176.0 143000.0 0.31 0.5618 0.9768 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.649 P24 mock treatment 190699.0 -283000.0 -0.58 450124.0 -39700.0 -0.09 -0.4743 -0.8025 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A01 compound treatment 685034.0 228000.0 0.47 585258.0 132000.0 0.29 0.5355 0.9712 1980313 ChemDiv1_022177 CCOc1cc(ccc1OCc2ccccc2)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A02 compound treatment 666778.0 210000.0 0.43 599112.0 146000.0 0.32 0.53 0.9878 1980314 ChemDiv1_022178 COc1ccc(cc1)C2(Oc3c(C=C2)c4C(=O)c5ccccc5-c4c6ccccc36)c7ccc(OC)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A03 compound treatment 712185.0 256000.0 0.53 616353.0 163000.0 0.35 0.6227 0.9809 1980315 ChemDiv1_022179 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(F)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A04 compound treatment 661916.0 205000.0 0.42 579986.0 127000.0 0.27 0.4937 0.9779 1980316 ChemDiv1_022180 Brc1ccc2N(CC(=O)NNc3c4ccccc4nc5ccccc35)C(=O)CN=C(c6ccccc6)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A05 compound treatment 682485.0 226000.0 0.47 631837.0 179000.0 0.39 0.603 0.9957 1625854 ChemDiv1_022181 CN(C)c1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A06 compound treatment 698991.0 242000.0 0.5 645820.0 193000.0 0.42 0.6485 0.9959 1204956 ChemDiv1_022182 Cc1nn2c3ccccc3n(CCN4CCCCC4)c2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A07 compound treatment 875925.0 419000.0 0.87 656081.0 203000.0 0.44 0.9225 0.9505 1980317 ChemDiv1_022183 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccc(Cl)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A08 compound treatment 709593.0 253000.0 0.52 633800.0 181000.0 0.39 0.6456 0.9898 1980318 ChemDiv1_022184 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4ccc(OC)c(OC)c4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A09 compound treatment 716452.0 260000.0 0.54 656853.0 204000.0 0.44 0.6909 0.9952 1980319 ChemDiv1_022185 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A10 compound treatment 744301.0 288000.0 0.59 671880.0 219000.0 0.47 0.7546 0.9937 1980320 ChemDiv1_022186 CCOC(=O)/C(=C\N1CCc2ccccc2C1)/C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A11 compound treatment 715172.0 259000.0 0.53 692430.0 239000.0 0.52 0.7435 0.9999 1518116 ChemDiv1_022187 Cc1c(Cl)cccc1N2C(=O)C3C(C2=O)C4(C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A12 compound treatment 700284.0 244000.0 0.5 645129.0 192000.0 0.42 0.6494 0.9955 1671124 ChemDiv1_022188 CCOC(=O)C(C)Oc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A13 compound treatment 709468.0 253000.0 0.52 664391.0 211000.0 0.46 0.6923 0.9978 1396702 ChemDiv1_022189 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(CCc5ccccc5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A14 compound treatment 708858.0 252000.0 0.52 642916.0 190000.0 0.41 0.6585 0.9931 1335301 ChemDiv1_022190 CCOC(=O)C(C)Oc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A15 compound treatment 726833.0 270000.0 0.56 665546.0 212000.0 0.46 0.7194 0.9954 1948526 ChemDiv1_022191 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A16 compound treatment 735688.0 279000.0 0.58 667096.0 214000.0 0.46 0.7347 0.9941 1157547 ChemDiv1_022192 CCN1C(=O)c2cccc3c(NC(=O)c4ccc(cc4)S(=O)(=O)N(CC(C)C)CC(C)C)ccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A17 compound treatment 732144.0 276000.0 0.57 669651.0 216000.0 0.47 0.7334 0.9954 1721276 ChemDiv1_022193 Cc1cc(C)c(NC(=O)C2CC2(c3ccccc3)c4ccccc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A18 compound treatment 696408.0 240000.0 0.49 650087.0 197000.0 0.43 0.6513 0.9972 1272983 ChemDiv1_022194 COc1ccc(cc1OC)C(CC(=O)c2ccco2)SCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A19 compound treatment 708764.0 252000.0 0.52 641088.0 188000.0 0.41 0.6556 0.9925 1980321 ChemDiv1_022195 Cc1c(N(CC(=O)N/N=C/c2ccc(C)cc2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A20 compound treatment 656433.0 200000.0 0.41 625680.0 172000.0 0.37 0.5556 0.9988 1980322 ChemDiv1_022196 COc1ccc(cc1OC)C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A21 compound treatment 661980.0 205000.0 0.42 631378.0 178000.0 0.39 0.5724 0.9989 1673260 ChemDiv1_022197 COc1cc(ccc1OC(C)C(=O)O)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A22 compound treatment 633600.0 177000.0 0.37 608768.0 156000.0 0.34 0.4964 0.9992 1724561 ChemDiv1_022198 Clc1ccc(cc1)C(=O)CC(SCc2ccco2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A23 mock treatment 608553.0 152000.0 0.31 593377.0 140000.0 0.3 0.4363 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 A24 mock treatment 267614.0 -189000.0 -0.39 216177.0 -237000.0 -0.51 -0.6387 -0.9909 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B01 compound treatment 668242.0 212000.0 0.44 610038.0 157000.0 0.34 0.5489 0.9922 1980323 ChemDiv1_022199 COc1cc(/C=C(/C#N)\c2nnc3CCCCCn23)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B02 compound treatment 694213.0 238000.0 0.49 613985.0 161000.0 0.35 0.5928 0.9859 1980324 ChemDiv1_022200 Brc1ccc(CN2C3=NCCN3c4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B03 compound treatment 734283.0 278000.0 0.57 639940.0 187000.0 0.4 0.6911 0.9854 1980325 ChemDiv1_022201 [O-][N+](=O)c1cccc(c1)C2=Nn3cnnc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B04 compound treatment 688017.0 231000.0 0.48 620546.0 167000.0 0.36 0.5938 0.9907 1197018 ChemDiv1_022202 CCC1CCc2c(C(=O)N)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B05 compound treatment 724063.0 267000.0 0.55 669995.0 217000.0 0.47 0.7221 0.9967 1571581 ChemDiv1_022203 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B06 compound treatment 698747.0 242000.0 0.5 653658.0 200000.0 0.43 0.6602 0.9975 1333771 ChemDiv1_022204 COc1ccc(CC(=O)NCC2(CCCC2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B07 compound treatment 740696.0 284000.0 0.59 663541.0 210000.0 0.46 0.7365 0.9922 1145915 ChemDiv1_022205 Cc1cccc(NCc2nnc3CCCCCn23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B08 compound treatment 731572.0 275000.0 0.57 681829.0 229000.0 0.49 0.7512 0.9977 1980326 ChemDiv1_022206 Cc1ccc(cc1)n2c(=O)c3c4CCCc4sc3n5c(SCC=C)nnc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B09 compound treatment 768929.0 312000.0 0.64 751102.0 298000.0 0.64 0.9118 1.0 1980327 ChemDiv1_022207 O=C(Nc1sc2CCCCc2c1c3nc4ccccc4s3)c5ccc(cc5)S(=O)(=O)N6CCc7ccccc67 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B10 compound treatment 729802.0 273000.0 0.56 689961.0 237000.0 0.51 0.7611 0.9989 1980328 ChemDiv1_022208 COC(=O)c1ccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B11 compound treatment 743166.0 287000.0 0.59 716446.0 263000.0 0.57 0.8211 0.9998 1980329 ChemDiv1_022209 CCCc1nnc2SCC(=Nn12)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B12 compound treatment 704085.0 247000.0 0.51 695666.0 242000.0 0.52 0.7323 0.9999 1980330 ChemDiv1_022210 CC(C/C=C\Cc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B13 compound treatment 745232.0 289000.0 0.6 718859.0 266000.0 0.57 0.8278 0.9998 1526113 ChemDiv1_022211 Cc1cccc(NC(=O)N2CC3CC(C2)c4cccc(=O)n4C3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B14 compound treatment 735688.0 279000.0 0.58 698383.0 245000.0 0.53 0.7826 0.9992 1980331 ChemDiv1_022212 Cc1ccc(NC(=O)/C(=C/c2ccc3OCOc3c2)/NC(=O)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B15 compound treatment 730393.0 274000.0 0.57 724015.0 271000.0 0.59 0.8141 0.9998 1139511 ChemDiv1_022213 CC12COC3(CC2CCC13C)C(=O)NCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B16 compound treatment 724286.0 268000.0 0.55 714531.0 261000.0 0.57 0.7906 0.9999 1946241 ChemDiv1_022214 COc1ccc(cc1OC)C2(CNC(=O)/C=C/c3ccco3)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B17 compound treatment 758528.0 302000.0 0.62 736986.0 284000.0 0.61 0.875 1.0 1372234 ChemDiv1_022215 CC12COC3(CC2CCC13C)C(=O)Nc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B18 compound treatment 715114.0 258000.0 0.53 669666.0 216000.0 0.47 0.7086 0.9979 1321883 ChemDiv1_022216 CCOc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B19 compound treatment 724699.0 268000.0 0.55 710874.0 258000.0 0.56 0.7856 1.0 1423608 ChemDiv1_022217 CC1(C)C2(C)CCC1(OC2=O)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B20 compound treatment 684489.0 228000.0 0.47 682615.0 229000.0 0.5 0.6837 0.9996 1980332 ChemDiv1_022218 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccccc4NC3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B21 compound treatment 688380.0 232000.0 0.48 667474.0 214000.0 0.46 0.6662 0.9999 1644643 ChemDiv1_022219 CCOc1ccc(cc1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B22 compound treatment 662849.0 206000.0 0.43 651761.0 199000.0 0.43 0.6049 1.0 1548625 ChemDiv1_022220 CC1(C)Nc2ccccc2-c3c1ssc3=Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B23 mock treatment 717960.0 261000.0 0.54 633925.0 181000.0 0.39 0.658 0.9875 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 B24 mock treatment 220334.0 -236000.0 -0.49 213109.0 -240000.0 -0.52 -0.7124 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C01 compound treatment 681906.0 225000.0 0.47 605407.0 152000.0 0.33 0.5618 0.9857 1980333 ChemDiv1_022221 CCOc1cc(ccc1OCc2ccc(Cl)cc2)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C02 compound treatment 687826.0 231000.0 0.48 630499.0 177000.0 0.38 0.6088 0.9941 1980334 ChemDiv1_022222 COC(=O)c1c(c2ccccc2)c3ccccc3c4OC(C=Cc14)(c5ccc(OC)cc5)c6ccc(OC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C03 compound treatment 742663.0 286000.0 0.59 648088.0 195000.0 0.42 0.7158 0.9864 1980335 ChemDiv1_022223 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4F)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C04 compound treatment 697026.0 240000.0 0.5 633051.0 180000.0 0.39 0.6261 0.9928 1980336 ChemDiv1_022224 FC(F)C(F)(F)C1=Nc2ccccc2N=C(C1)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C05 compound treatment 740407.0 284000.0 0.59 709698.0 256000.0 0.56 0.8068 0.9996 1601243 ChemDiv1_022225 COc1ccccc1C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C06 compound treatment 713533.0 257000.0 0.53 705825.0 253000.0 0.55 0.7616 0.9999 1261898 ChemDiv1_022226 Cc1nn2c3ccccc3n(CC(=O)c4ccc(Cl)cc4)c2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C07 compound treatment 760262.0 304000.0 0.63 731616.0 278000.0 0.6 0.8693 0.9998 1980337 ChemDiv1_022227 CCCC1SC2=NC(=C(C(N2C1=O)c3c(OC)ccc4ccccc34)C(=O)OCC)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C08 compound treatment 738401.0 282000.0 0.58 697459.0 244000.0 0.53 0.7851 0.9989 1324158 ChemDiv1_022228 Oc1ccc(cc1)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C09 compound treatment 746830.0 290000.0 0.6 728210.0 275000.0 0.6 0.8445 1.0 1980338 ChemDiv1_022229 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C10 compound treatment 752208.0 296000.0 0.61 695294.0 242000.0 0.52 0.8019 0.9971 1482211 ChemDiv1_022230 CCOc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C11 compound treatment 770070.0 313000.0 0.65 762846.0 310000.0 0.67 0.9314 0.9998 1779062 ChemDiv1_022231 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C12 compound treatment 734691.0 278000.0 0.57 686329.0 233000.0 0.5 0.7626 0.9979 1454651 ChemDiv1_022232 CCOc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C13 compound treatment 735643.0 279000.0 0.58 737780.0 285000.0 0.62 0.8428 0.9994 1253605 ChemDiv1_022233 Clc1cccc(NC(=O)C2CC2(c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C14 compound treatment 727250.0 271000.0 0.56 725245.0 272000.0 0.59 0.8113 0.9997 1980339 ChemDiv1_022234 CCCOc1cc(OCCC)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C15 compound treatment 765362.0 309000.0 0.64 762176.0 309000.0 0.67 0.9235 0.9997 1938892 ChemDiv1_022235 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C16 compound treatment 748312.0 292000.0 0.6 723564.0 270000.0 0.59 0.8395 0.9999 1436017 ChemDiv1_022236 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3n(c4CCCC(=O)c4c3c2)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C17 compound treatment 731090.0 274000.0 0.57 743893.0 291000.0 0.63 0.8455 0.9986 1980340 ChemDiv1_022237 Cc1ccc(cc1)C2(CC2C(=O)Nc3cccc(c3)C(F)(F)F)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C18 compound treatment 693256.0 237000.0 0.49 719019.0 266000.0 0.58 0.7522 0.9967 1980341 ChemDiv1_022238 [O-][N+](=O)c1ccc(cc1)C2CC(=Nc3ccccc3S2)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C19 compound treatment 710058.0 253000.0 0.52 729504.0 276000.0 0.6 0.7928 0.9978 1980342 ChemDiv1_022239 Cc1c(N(CC(=O)N/N=C/c2ccc3OCOc3c2)S(=O)(=O)c4ccccc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C20 compound treatment 680829.0 224000.0 0.46 698252.0 245000.0 0.53 0.7023 0.9977 1980343 ChemDiv1_022240 Clc1ccccc1C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C21 compound treatment 699091.0 242000.0 0.5 730724.0 278000.0 0.6 0.7786 0.9959 1151088 ChemDiv1_022241 Cn1cnc2n(C)c(=O)n(Cc3ccc(F)cc3)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C22 compound treatment 671538.0 215000.0 0.44 667641.0 214000.0 0.46 0.6419 0.9997 1980344 ChemDiv1_022242 C(Nc1nc(c2ccccc2)[n+](s1)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C23 mock treatment 671576.0 215000.0 0.44 671814.0 219000.0 0.47 0.6483 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 C24 mock treatment 219098.0 -238000.0 -0.49 226114.0 -227000.0 -0.49 -0.6943 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D01 compound treatment 682119.0 225000.0 0.47 618867.0 166000.0 0.36 0.5827 0.9917 1980345 ChemDiv1_022243 COc1cc(/C=C(\C#N)/c2nnc3CCCCCn23)ccc1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D02 compound treatment 683224.0 227000.0 0.47 635222.0 182000.0 0.39 0.6093 0.9963 1980346 ChemDiv1_022244 Clc1ccc(CN2C3=NCCN3c4ccccc24)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D03 compound treatment 696915.0 240000.0 0.5 640483.0 187000.0 0.41 0.6373 0.995 1980347 ChemDiv1_022245 CCOc1ccc(cc1)C2=Nn3cnnc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D04 compound treatment 686998.0 230000.0 0.48 678541.0 225000.0 0.49 0.6811 0.9999 1980348 ChemDiv1_022246 FC(F)(F)C(=O)Nc1sc2CCCc2c1C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D05 compound treatment 713702.0 257000.0 0.53 677193.0 224000.0 0.48 0.718 0.999 1599180 ChemDiv1_022247 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D06 compound treatment 699584.0 243000.0 0.5 629849.0 177000.0 0.38 0.625 0.991 1153562 ChemDiv1_022248 Cn1c(NCCO)nc2-c3ccccc3CC4(CCCCC4)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D07 compound treatment 747714.0 291000.0 0.6 696764.0 244000.0 0.53 0.7976 0.9979 1589069 ChemDiv1_022249 COC(=O)c1ccc(cc1)C(=O)Nc2sc3CC(C)CCc3c2c4nc5ccccc5s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D08 compound treatment 731512.0 275000.0 0.57 678483.0 225000.0 0.49 0.746 0.9971 1980349 ChemDiv1_022250 Cc1ccc(cc1)n2c(=O)c3c4CCCc4sc3n5c(SCC(=C)c6ccccc6)nnc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D09 compound treatment 762923.0 306000.0 0.63 710230.0 257000.0 0.56 0.8404 0.998 1980350 ChemDiv1_022251 CC1CCc2c(c(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2C1)c6nc7ccccc7s6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D10 compound treatment 718388.0 262000.0 0.54 699918.0 247000.0 0.53 0.7596 1.0 1980351 ChemDiv1_022252 OC(=O)c1cccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D11 compound treatment 780502.0 324000.0 0.67 734345.0 281000.0 0.61 0.903 0.9989 1980352 ChemDiv1_022253 CCCc1nnc2SCC(=Nn12)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D12 compound treatment 718009.0 261000.0 0.54 663022.0 210000.0 0.45 0.7026 0.9963 1980353 ChemDiv1_022254 OCCN(CCO)C(=O)/C(=C/c1cccc(c1)[N+](=O)[O-])/NC(=O)c2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D13 compound treatment 761293.0 305000.0 0.63 718217.0 265000.0 0.57 0.8503 0.9989 1376451 ChemDiv1_022255 CCOC(=O)c1ccc(NC(=O)N2CC3CC(C2)c4cccc(=O)n4C3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D14 compound treatment 717683.0 261000.0 0.54 714611.0 261000.0 0.57 0.7811 0.9997 1980354 ChemDiv1_022256 COc1ccc(NC(=O)/C(=C/c2ccc3OCOc3c2)/NC(=O)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D15 compound treatment 766882.0 310000.0 0.64 731472.0 278000.0 0.6 0.8787 0.9995 1317873 ChemDiv1_022257 CCN(CC)C(=O)C12CC3CCC2(C)C3(C)CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D16 compound treatment 742143.0 286000.0 0.59 726352.0 273000.0 0.59 0.8348 1.0 1567465 ChemDiv1_022258 COc1ccc(cc1OC)C2(CNC(=O)Cc3ccccc3)CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D17 compound treatment 747604.0 291000.0 0.6 732594.0 279000.0 0.6 0.8523 1.0 1356136 ChemDiv1_022259 CC12COC3(CC2CCC13C)C(=O)Nc4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D18 compound treatment 706834.0 250000.0 0.52 675368.0 222000.0 0.48 0.7052 0.9994 1205383 ChemDiv1_022260 COc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D19 compound treatment 716883.0 260000.0 0.54 700823.0 248000.0 0.54 0.7588 1.0 1212990 ChemDiv1_022261 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D20 compound treatment 664012.0 207000.0 0.43 683026.0 230000.0 0.5 0.6544 0.9972 1980355 ChemDiv1_022262 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)ccc4NC3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D21 compound treatment 698489.0 242000.0 0.5 686275.0 233000.0 0.5 0.7097 1.0 1727195 ChemDiv1_022263 OC(CN1C(=O)CCC1=O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D22 compound treatment 698070.0 241000.0 0.5 657811.0 205000.0 0.44 0.6655 0.9983 1450327 ChemDiv1_022264 COc1ccc2NC(C)(C)c3ssc(=Nc4ccccc4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D23 mock treatment 644401.0 188000.0 0.39 664226.0 211000.0 0.46 0.597 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 D24 mock treatment 219402.0 -237000.0 -0.49 258179.0 -195000.0 -0.42 -0.6448 -0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E01 compound treatment 687855.0 231000.0 0.48 636118.0 183000.0 0.4 0.6174 0.9957 1980356 ChemDiv1_022265 COc1cc(ccc1O)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E02 compound treatment 662985.0 206000.0 0.43 641446.0 188000.0 0.41 0.5893 0.9998 1250279 ChemDiv1_022266 COC(=O)c1c(O)c2ccccc2c3OC(C=Cc13)(c4ccc(OC)cc4)c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E03 compound treatment 693341.0 237000.0 0.49 694243.0 241000.0 0.52 0.7144 0.9995 1980357 ChemDiv1_022267 COc1ccc(C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E04 compound treatment 672859.0 216000.0 0.45 654554.0 201000.0 0.44 0.6238 0.9999 1980358 ChemDiv1_022268 [O-][N+](=O)c1cc(ccc1N2CCCCC2)C(=O)N3CC(=O)Nc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E05 compound treatment 721411.0 265000.0 0.55 739255.0 286000.0 0.62 0.8243 0.9981 1721069 ChemDiv1_022269 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(OCc5ccccc5Cl)cc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E06 compound treatment 701389.0 245000.0 0.51 673507.0 220000.0 0.48 0.6944 0.9996 1580525 ChemDiv1_022270 Cc1nn2c3ccccc3n(CC(=O)c4ccc(Br)cc4)c2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E07 compound treatment 753782.0 297000.0 0.61 728183.0 275000.0 0.6 0.8546 0.9999 1779061 ChemDiv1_022271 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E08 compound treatment 729449.0 273000.0 0.56 684999.0 232000.0 0.5 0.753 0.9983 1487191 ChemDiv1_022272 COc1cc(cc(OC)c1OC)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E09 compound treatment 743567.0 287000.0 0.59 663975.0 211000.0 0.46 0.7414 0.9917 1931095 ChemDiv1_022273 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E10 compound treatment 703305.0 247000.0 0.51 703746.0 251000.0 0.54 0.7435 0.9995 1401998 ChemDiv1_022274 CCCOc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E11 compound treatment 770470.0 314000.0 0.65 728155.0 275000.0 0.6 0.8789 0.9991 1980359 ChemDiv1_022275 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E12 compound treatment 686754.0 230000.0 0.48 684518.0 231000.0 0.5 0.6899 0.9997 1685253 ChemDiv1_022276 CCCOc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E13 compound treatment 761875.0 305000.0 0.63 741232.0 288000.0 0.62 0.8864 1.0 1265824 ChemDiv1_022277 Fc1ccc(NC(=O)C2CC2(c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E14 compound treatment 712569.0 256000.0 0.53 742086.0 289000.0 0.63 0.8157 0.9965 1980360 ChemDiv1_022278 CCCCOc1cc(OCCCC)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E15 compound treatment 766279.0 310000.0 0.64 762568.0 309000.0 0.67 0.9254 0.9997 1980361 ChemDiv1_022279 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)c(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E16 compound treatment 702486.0 246000.0 0.51 693316.0 240000.0 0.52 0.7263 0.9999 1217518 ChemDiv1_022280 O=S(=O)(Nc1ccc2oc3CCCCc3c2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E17 compound treatment 737053.0 280000.0 0.58 758714.0 305000.0 0.66 0.8769 0.9978 1404993 ChemDiv1_022281 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccc(Br)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E18 compound treatment 697681.0 241000.0 0.5 717753.0 265000.0 0.57 0.7567 0.9976 1980362 ChemDiv1_022282 FC(F)Oc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E19 compound treatment 733775.0 277000.0 0.57 737025.0 284000.0 0.61 0.8389 0.9994 1980363 ChemDiv1_022283 Cc1c(N(CC(=O)NN=C2CCC(CC2)C(C)(C)C)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E20 compound treatment 684319.0 228000.0 0.47 714923.0 262000.0 0.57 0.7329 0.9957 1090041 ChemDiv1_022284 COc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E21 compound treatment 701327.0 245000.0 0.51 766833.0 314000.0 0.68 0.8372 0.9894 1132070 ChemDiv1_022285 NC1=C(C#N)C(C(=c2sc(=Cc3ccc4OCOc4c3)c(=O)n12)C#N)c5ccc6OCOc6c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E22 compound treatment 699482.0 243000.0 0.5 687620.0 234000.0 0.51 0.7132 1.0 1980364 ChemDiv1_022286 Oc1ccc(/C=C(/C#N)\c2nnc3CCCCCn23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E23 mock treatment 685281.0 229000.0 0.47 669800.0 217000.0 0.47 0.6652 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 E24 mock treatment 214794.0 -242000.0 -0.5 222732.0 -230000.0 -0.5 -0.7057 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F01 compound treatment 677950.0 221000.0 0.46 609556.0 156000.0 0.34 0.5623 0.9891 1980365 ChemDiv1_022287 COc1ccc(/C=C(\C#N)/c2nnc3CCCCCn23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F02 compound treatment 666576.0 210000.0 0.43 647493.0 194000.0 0.42 0.6038 0.9999 1686926 ChemDiv1_022288 CCC(C)(C)C1CCc2c(C#N)c(NC(=O)c3c(C)onc3c4ccccc4Cl)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F03 compound treatment 719931.0 263000.0 0.54 687106.0 234000.0 0.51 0.7423 0.9994 1980366 ChemDiv1_022289 CC/C(=C(/C#N)\c1nnc2CCCCCn12)/O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F04 compound treatment 700218.0 244000.0 0.5 664396.0 211000.0 0.46 0.6788 0.9989 1980367 ChemDiv1_022290 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F05 compound treatment 723146.0 267000.0 0.55 696729.0 244000.0 0.53 0.7617 0.9998 1648380 ChemDiv1_022291 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N3CC(C)OC(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F06 compound treatment 705923.0 249000.0 0.51 687973.0 235000.0 0.51 0.7232 1.0 1327653 ChemDiv1_022292 CCOC(=O)C1=C(NC(=S)NC(=O)c2ccccc2)c3ccccc3CC41CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F07 compound treatment 767370.0 311000.0 0.64 713607.0 260000.0 0.56 0.8521 0.9979 1980368 ChemDiv1_022293 Cc1cn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)nc1NCCO 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F08 compound treatment 744731.0 288000.0 0.59 703438.0 250000.0 0.54 0.8035 0.9989 1492805 ChemDiv1_022294 COc1ccc(cc1)n2c(=O)c3c4CCCCCc4sc3n5c(C)nnc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F09 compound treatment 934066.0 477000.0 0.99 857708.0 404000.0 0.88 1.316 0.9983 1140819 ChemDiv1_022295 CCN1C(=O)c2cccc3c(NC(=O)c4ccc(cc4)S(=O)(=O)N(CC=C)CC=C)ccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F10 compound treatment 729608.0 273000.0 0.56 699091.0 246000.0 0.53 0.7748 0.9996 1980369 ChemDiv1_022296 COc1ccccc1C(=O)N/C(=C/c2ccc3OCOc3c2)/C(=O)Nc4ccc(cc4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F11 compound treatment 740435.0 284000.0 0.59 745318.0 292000.0 0.63 0.8613 0.9993 1141397 ChemDiv1_022297 COc1ccc(c2cn3nc(COc4cc(C)ccc4C(C)C)n5CCCCc2c53)c(F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F12 compound treatment 716558.0 260000.0 0.54 700981.0 248000.0 0.54 0.7586 1.0 1980370 ChemDiv1_022298 OCCN(CCO)C(=O)/C(=C/c1ccc(cc1)[N+](=O)[O-])/NC(=O)c2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F13 compound treatment 783468.0 327000.0 0.67 732366.0 279000.0 0.6 0.9043 0.9985 1980371 ChemDiv1_022299 CCN1C(=O)c2cccc3c(NC(=S)NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5)ccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F14 compound treatment 740952.0 284000.0 0.59 696468.0 243000.0 0.53 0.7873 0.9985 1944199 ChemDiv1_022300 Fc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)NCc3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F15 compound treatment 777540.0 321000.0 0.66 721260.0 268000.0 0.58 0.8787 0.9978 1190116 ChemDiv1_022301 CC12COC3(CC2CCC13C)C(=O)N4CCCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F16 compound treatment 702343.0 246000.0 0.51 677488.0 224000.0 0.49 0.7019 0.9998 1349245 ChemDiv1_022302 COc1ccc(cc1OC)C2(CNC(=O)C(c3ccccc3)c4ccccc4)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F17 compound treatment 734288.0 278000.0 0.57 715119.0 262000.0 0.57 0.8061 1.0 1384450 ChemDiv1_022303 COC(=O)c1ccc(NC(=O)C23CC4CCC3(C)C4(C)CO2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F18 compound treatment 709339.0 253000.0 0.52 675932.0 223000.0 0.48 0.7097 0.9992 1421333 ChemDiv1_022304 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3ccc(cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F19 compound treatment 711576.0 255000.0 0.53 701761.0 249000.0 0.54 0.7525 0.9999 1568070 ChemDiv1_022305 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F20 compound treatment 682765.0 226000.0 0.47 703895.0 251000.0 0.54 0.7137 0.9972 1980372 ChemDiv1_022306 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)ccc4N(C)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F21 compound treatment 712848.0 256000.0 0.53 706032.0 253000.0 0.55 0.7609 0.9999 1682570 ChemDiv1_022307 Cc1nc2CC(C)(C)CC(N)c2c3c4ccccc4[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F22 compound treatment 649759.0 193000.0 0.4 656116.0 203000.0 0.44 0.5924 0.9988 1932838 ChemDiv1_022308 COc1ccc(N=c2ssc3c2-c4cc(OC)ccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F23 mock treatment 670558.0 214000.0 0.44 681208.0 228000.0 0.49 0.6612 0.9985 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 F24 mock treatment 241571.0 -215000.0 -0.44 226230.0 -227000.0 -0.49 -0.6613 -0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G01 compound treatment 664697.0 208000.0 0.43 620530.0 167000.0 0.36 0.5598 0.9964 1980373 ChemDiv1_022309 COc1ccc(cc1OC)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G02 compound treatment 683776.0 227000.0 0.47 642620.0 189000.0 0.41 0.6214 0.9978 1635451 ChemDiv1_022310 COc1ccc(cc1)N(CN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G03 compound treatment 686744.0 230000.0 0.48 679314.0 226000.0 0.49 0.6819 0.9999 1980374 ChemDiv1_022311 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OCc5ccc(F)cc5)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G04 compound treatment 692247.0 236000.0 0.49 651259.0 198000.0 0.43 0.647 0.998 2969 ChemDiv1_022312 [O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G05 compound treatment 706461.0 250000.0 0.52 710612.0 257000.0 0.56 0.7586 0.9993 1527805 ChemDiv1_022313 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(OCc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G06 compound treatment 798937.0 342000.0 0.71 838132.0 385000.0 0.83 1.0888 0.9966 1944396 ChemDiv1_022314 CN1C2=NC(=O)/C(=C/c3ccc(s3)[N+](=O)[O-])/N2c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G07 compound treatment 721891.0 265000.0 0.55 714267.0 261000.0 0.57 0.7867 0.9999 1147259 ChemDiv1_022315 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Br)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G08 compound treatment 706921.0 250000.0 0.52 726790.0 274000.0 0.59 0.784 0.9977 1147569 ChemDiv1_022316 COc1ccc(OC)c(c1)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G09 compound treatment 727305.0 271000.0 0.56 711660.0 258000.0 0.56 0.7906 1.0 1980375 ChemDiv1_022317 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(C)c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G10 compound treatment 716240.0 260000.0 0.54 673460.0 220000.0 0.48 0.716 0.9983 1941511 ChemDiv1_022318 CCCCOc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G11 compound treatment 732171.0 276000.0 0.57 722367.0 269000.0 0.58 0.8141 0.9999 1980376 ChemDiv1_022319 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G12 compound treatment 707087.0 250000.0 0.52 662735.0 210000.0 0.45 0.6862 0.9979 1942098 ChemDiv1_022320 CCCCOc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G13 compound treatment 769475.0 313000.0 0.65 744905.0 292000.0 0.63 0.9031 0.9999 1701465 ChemDiv1_022321 Cc1ccc(NC(=O)C2CC2(c3ccccc3)c4ccccc4)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G14 compound treatment 702716.0 246000.0 0.51 713744.0 261000.0 0.56 0.7579 0.9986 1255508 ChemDiv1_022322 CCOC(=O)COc1cc(OCC(=O)OCC)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G15 compound treatment 761575.0 305000.0 0.63 718121.0 265000.0 0.57 0.8505 0.9989 1627565 ChemDiv1_022323 C=CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G16 compound treatment 744577.0 288000.0 0.59 732850.0 280000.0 0.61 0.8483 1.0 1929748 ChemDiv1_022324 CC(=O)c1c(C)n(c2ccc(NS(=O)(=O)c3ccccc3)cc12)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G17 compound treatment 733161.0 277000.0 0.57 758869.0 306000.0 0.66 0.8714 0.9973 1980377 ChemDiv1_022325 Cc1cccc(c1)C2(CC2C(=O)Nc3cccc(c3)C(F)(F)F)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G18 compound treatment 703766.0 247000.0 0.51 672188.0 219000.0 0.47 0.6959 0.9993 1980378 ChemDiv1_022326 COc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G19 compound treatment 748997.0 292000.0 0.6 742937.0 290000.0 0.63 0.8702 0.9998 1980379 ChemDiv1_022327 Cc1c(N(CC(=O)N/N=C/c2ccccn2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G20 compound treatment 623977.0 167000.0 0.35 719330.0 266000.0 0.58 0.6515 0.9701 1129684 ChemDiv1_022328 O=C(CCSc1ccccc1)Nc2sc3CCCCc3c2c4nc5ccccc5s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G21 compound treatment 665675.0 209000.0 0.43 714283.0 261000.0 0.57 0.7047 0.9911 1980380 ChemDiv1_022329 Brc1ccc(cc1)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G22 compound treatment 677521.0 221000.0 0.46 681733.0 229000.0 0.49 0.6722 0.9992 1980381 ChemDiv1_022330 CCCCc1nnc2SCC(=Nn12)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G23 mock treatment 671347.0 215000.0 0.44 680997.0 228000.0 0.49 0.662 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 G24 mock treatment 201129.0 -256000.0 -0.53 221612.0 -232000.0 -0.5 -0.7274 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H01 compound treatment 682398.0 226000.0 0.47 591641.0 138000.0 0.3 0.5414 0.9772 1419430 ChemDiv1_022331 COc1ccc(cc1)c2c(C(=O)Nc3ccc(Cl)cc3)n4nc(c5ccc(Br)cc5)n6CCCCc2c64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H02 compound treatment 676671.0 220000.0 0.45 610154.0 157000.0 0.34 0.5614 0.9897 1122092 ChemDiv1_022332 CC1CCc2cc(F)ccc2N1C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H03 compound treatment 697460.0 241000.0 0.5 650022.0 197000.0 0.43 0.6527 0.997 1495460 ChemDiv1_022333 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H04 compound treatment 685004.0 228000.0 0.47 625850.0 173000.0 0.37 0.5976 0.9934 1461497 ChemDiv1_022334 COc1ccc(OC)c(c1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H05 compound treatment 701429.0 245000.0 0.51 653814.0 201000.0 0.43 0.6643 0.9971 1241054 ChemDiv1_022335 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(I)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H06 compound treatment 680349.0 224000.0 0.46 645491.0 192000.0 0.42 0.6208 0.9987 1980382 ChemDiv1_022336 OCCCNc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H07 compound treatment 744961.0 288000.0 0.6 696433.0 243000.0 0.53 0.7931 0.9981 1980383 ChemDiv1_022337 O=c1nc(NCc2ccccc2)ccn1c3nc(oc3c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H08 compound treatment 708967.0 252000.0 0.52 673704.0 220000.0 0.48 0.7058 0.999 1980384 ChemDiv1_022338 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nncn42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H09 compound treatment 712700.0 256000.0 0.53 669108.0 216000.0 0.47 0.7042 0.9981 1980385 ChemDiv1_022339 Clc1ccc(cc1)C2=Nn3c(nnc3SC2)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H10 compound treatment 729642.0 273000.0 0.56 675472.0 222000.0 0.48 0.7387 0.9969 1980386 ChemDiv1_022340 COC(=O)c1ccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4OC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H11 compound treatment 737239.0 281000.0 0.58 690829.0 238000.0 0.51 0.7733 0.9982 1136306 ChemDiv1_022341 CCNC(=S)N1CC2CC(C1)c3cccc(=O)n3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H12 compound treatment 718233.0 262000.0 0.54 658916.0 206000.0 0.45 0.6967 0.9954 1980387 ChemDiv1_022342 Brc1ccc(cc1)C(=O)N/C(=C\c2ccccc2)/C(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H13 compound treatment 705418.0 249000.0 0.51 685656.0 232000.0 0.5 0.7189 0.9999 1980388 ChemDiv1_022343 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3sc4CCCCc4c3c5nc6ccccc6s5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H14 compound treatment 729217.0 273000.0 0.56 696684.0 243000.0 0.53 0.7705 0.9995 1980389 ChemDiv1_022344 CC(C)Oc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)NCc3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H15 compound treatment 756394.0 300000.0 0.62 714770.0 262000.0 0.57 0.8379 0.999 1150484 ChemDiv1_022345 Cc1ccccc1NC(=O)C23CC4CCC3(C)C4(C)CO2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H16 compound treatment 730160.0 274000.0 0.56 674217.0 221000.0 0.48 0.7375 0.9966 1980390 ChemDiv1_022346 CC(N1CCCCC1)C(=O)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H17 compound treatment 733223.0 277000.0 0.57 716143.0 263000.0 0.57 0.8061 1.0 1980391 ChemDiv1_022347 CN(C)C(=O)C1(CCC2(C)C(=O)O1)C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H18 compound treatment 702383.0 246000.0 0.51 672755.0 220000.0 0.48 0.6947 0.9995 1980392 ChemDiv1_022348 CCOc1ccc2N(C(=O)c3ccccc3)C(C)(C)C4=C(c2c1)C5(SC(=C(S5)C(=O)OC)C(=O)OC)C(=C(S4)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H19 compound treatment 733575.0 277000.0 0.57 693814.0 241000.0 0.52 0.7725 0.9989 1283151 ChemDiv1_022349 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H20 compound treatment 697763.0 241000.0 0.5 672882.0 220000.0 0.48 0.6882 0.9997 1980393 ChemDiv1_022350 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(OCC)ccc4NC3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H21 compound treatment 680195.0 224000.0 0.46 694534.0 241000.0 0.52 0.6957 0.9981 1646309 ChemDiv1_022351 Cn1c(=O)n(C)c2nc(Br)n(CC(=O)c3ccc(Br)cc3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H22 compound treatment 687419.0 231000.0 0.48 670853.0 218000.0 0.47 0.67 1.0 1510167 ChemDiv1_022352 COc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H23 mock treatment 674666.0 218000.0 0.45 647379.0 194000.0 0.42 0.6154 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 H24 mock treatment 229413.0 -227000.0 -0.47 213203.0 -240000.0 -0.52 -0.699 -0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I01 compound treatment 659240.0 203000.0 0.42 619539.0 166000.0 0.36 0.5503 0.9972 1980394 ChemDiv1_022353 COc1ccc(cc1)C(=O)Oc2ccc(cc2)C(c3c(C)nn(c3O)c4ccccc4)c5c(C)nn(c5O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I02 compound treatment 651879.0 195000.0 0.4 626525.0 173000.0 0.38 0.5502 0.9994 1980395 ChemDiv1_022354 Nc1cccc(c1)c2cc(nc(n2)c3cccc(N)c3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I03 compound treatment 723531.0 267000.0 0.55 695790.0 243000.0 0.53 0.7608 0.9997 1980396 ChemDiv1_022355 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4OCc5ccc(F)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I04 compound treatment 659835.0 203000.0 0.42 653260.0 200000.0 0.43 0.6028 0.9999 1922363 ChemDiv1_022356 [O-][N+](=O)c1ccc(Cl)c(c1)C2=NCC(=O)Nc3ccc(cc23)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I05 compound treatment 687336.0 231000.0 0.48 702860.0 250000.0 0.54 0.7188 0.998 1185546 ChemDiv1_022357 COc1cc(ccc1OCc2ccccc2)C3C4=C(CC(C)(C)CC4=O)NC5=C3C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I06 compound treatment 698681.0 242000.0 0.5 683142.0 230000.0 0.5 0.7052 1.0 1980397 ChemDiv1_022358 [O-][N+](=O)c1ccc(/C=C/2\N3C(=NC2=O)N(CCN4CCCCC4)c5ccccc35)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I07 compound treatment 736170.0 280000.0 0.58 717469.0 264000.0 0.57 0.8125 1.0 1249531 ChemDiv1_022359 Cc1c(Cl)cccc1NC(=O)C2CC2(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I08 compound treatment 702026.0 245000.0 0.51 686422.0 233000.0 0.5 0.7151 1.0 1689269 ChemDiv1_022360 COc1ccc(cc1)c2nc(c([nH]2)c3cccc(OC)c3)c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I09 compound treatment 687086.0 230000.0 0.48 684125.0 231000.0 0.5 0.6898 0.9997 1980398 ChemDiv1_022361 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I10 compound treatment 730908.0 274000.0 0.57 691805.0 239000.0 0.52 0.7655 0.9989 1308304 ChemDiv1_022362 COC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I11 compound treatment 691740.0 235000.0 0.49 715968.0 263000.0 0.57 0.7453 0.9969 1980399 ChemDiv1_022363 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3c(C)cc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I12 compound treatment 728424.0 272000.0 0.56 697803.0 245000.0 0.53 0.7711 0.9996 1179387 ChemDiv1_022364 COC(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I13 compound treatment 704969.0 248000.0 0.51 712290.0 259000.0 0.56 0.759 0.999 1980400 ChemDiv1_022365 CCOC(=O)C1=NNC2(C)C1C(=O)N(C2=O)c3ccc(C)c(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I14 compound treatment 685817.0 229000.0 0.47 660870.0 208000.0 0.45 0.6523 0.9997 1630385 ChemDiv1_022366 CCOC(=O)C(C)Oc1cc(OC(C)C(=O)OCC)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I15 compound treatment 745756.0 289000.0 0.6 724934.0 272000.0 0.59 0.8379 1.0 1942093 ChemDiv1_022367 Cc1cc(ccc1N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I16 compound treatment 719663.0 263000.0 0.54 712969.0 260000.0 0.56 0.7815 0.9998 1980401 ChemDiv1_022368 COc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I17 compound treatment 639453.0 183000.0 0.38 735760.0 283000.0 0.61 0.6993 0.9731 1206775 ChemDiv1_022369 Cc1cccc(c1)C2(CC2C(=O)Nc3ccc(F)cc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I18 compound treatment 684523.0 228000.0 0.47 665289.0 212000.0 0.46 0.6572 0.9999 1980402 ChemDiv1_022370 FC(F)(F)c1ccc(cc1)C(CC(=O)c2ccco2)SCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I19 compound treatment 701174.0 245000.0 0.5 726008.0 273000.0 0.59 0.7745 0.997 1980403 ChemDiv1_022371 Cc1c(N(CC(=O)NN=C2CCCCC2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I20 compound treatment 1118000.0 661000.0 1.37 1231424.0 778000.0 1.68 2.1564 0.9946 1980404 ChemDiv1_022372 COC(=O)CSc1ccc2-c3ccccc3C(=O)c4cccc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I21 compound treatment 704856.0 248000.0 0.51 726905.0 274000.0 0.59 0.7812 0.9974 1980405 ChemDiv1_022373 COc1ccc(OC)c(C=c2sc3nc4cc(Br)cnc4n3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I22 compound treatment 700732.0 244000.0 0.5 698707.0 245000.0 0.53 0.732 0.9996 1448600 ChemDiv1_022374 Nc1ccccc1c2nnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I23 mock treatment 671904.0 215000.0 0.44 664845.0 212000.0 0.46 0.6381 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 I24 mock treatment 218606.0 -238000.0 -0.49 226481.0 -227000.0 -0.49 -0.6944 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J01 compound treatment 684678.0 228000.0 0.47 589570.0 136000.0 0.3 0.5416 0.9747 1608702 ChemDiv1_022375 C=CCNC(=S)Nc1ccc(cc1)c2nnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J02 compound treatment 707284.0 251000.0 0.52 646179.0 193000.0 0.42 0.6612 0.9944 1688362 ChemDiv1_022376 CCCOC(=O)c1c(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)sc4CC(C)CCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J03 compound treatment 728892.0 272000.0 0.56 657937.0 205000.0 0.44 0.7107 0.9931 1185811 ChemDiv1_022377 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J04 compound treatment 651963.0 195000.0 0.4 644948.0 192000.0 0.41 0.5786 0.9999 1219080 ChemDiv1_022378 CC(C)C1(CN2CC3(CN(C1)C2c4c(O)ccc5ccccc45)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J05 compound treatment 732688.0 276000.0 0.57 678946.0 226000.0 0.49 0.7484 0.9971 1502635 ChemDiv1_022379 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc4OCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J06 compound treatment 719025.0 262000.0 0.54 644087.0 191000.0 0.41 0.6751 0.9911 1545802 ChemDiv1_022380 CCOC(=O)c1c(NC(=O)c2ccco2)sc3CC(CCc13)(C#N)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J07 compound treatment 728562.0 272000.0 0.56 714944.0 262000.0 0.57 0.7975 1.0 1980406 ChemDiv1_022381 CNc1ccn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J08 compound treatment 711230.0 255000.0 0.53 687141.0 234000.0 0.51 0.7296 0.9998 1980407 ChemDiv1_022382 Cc1nnc2n(c3ccccc3)c(=O)c4c(C)c(C)sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J09 compound treatment 727321.0 271000.0 0.56 701373.0 248000.0 0.54 0.7749 0.9998 1980408 ChemDiv1_022383 COc1cc(cc(OC)c1OC)C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J10 compound treatment 736289.0 280000.0 0.58 673109.0 220000.0 0.48 0.7447 0.9954 1980409 ChemDiv1_022384 OC(=O)c1cccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccc(Br)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J11 compound treatment 742754.0 286000.0 0.59 685690.0 232000.0 0.5 0.7734 0.9968 1980410 ChemDiv1_022385 CCCCNC(=S)N1CC2CC(C1)c3cccc(=O)n3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J12 compound treatment 718607.0 262000.0 0.54 652651.0 199000.0 0.43 0.6876 0.9938 1980411 ChemDiv1_022386 Brc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J13 compound treatment 722453.0 266000.0 0.55 693714.0 240000.0 0.52 0.7561 0.9997 1472558 ChemDiv1_022387 CC12COC3(CC2CCC13C)C(=O)N4CCN(CC4)c5ccccn5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J14 compound treatment 666852.0 210000.0 0.43 692589.0 239000.0 0.52 0.6732 0.9961 1980412 ChemDiv1_022388 [O-][N+](=O)c1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)NCc3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J15 compound treatment 759495.0 303000.0 0.63 677459.0 224000.0 0.49 0.7853 0.9922 1740683 ChemDiv1_022389 CC12COC3(CC2CCC13C)C(=O)Nc4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J16 compound treatment 715931.0 259000.0 0.54 689039.0 236000.0 0.51 0.7394 0.9997 1980413 ChemDiv1_022390 CC(N1CCOCC1)C(=O)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J17 compound treatment 725479.0 269000.0 0.55 679620.0 226000.0 0.49 0.7389 0.9981 1385894 ChemDiv1_022391 CC1(C)C2(C)CCC1(OC2=O)C(=O)NCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J18 compound treatment 708849.0 252000.0 0.52 691384.0 238000.0 0.52 0.7327 1.0 1919823 ChemDiv1_022392 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)ccc4NC3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J19 compound treatment 810355.0 354000.0 0.73 791007.0 338000.0 0.73 1.0333 1.0 1648113 ChemDiv1_022393 O=C(NC1CS(=O)(=O)CC1NCc2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J20 compound treatment 701883.0 245000.0 0.51 674500.0 221000.0 0.48 0.6967 0.9996 1980414 ChemDiv1_022394 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccccc4N(C)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J21 compound treatment 677902.0 221000.0 0.46 676770.0 224000.0 0.48 0.6651 0.9996 1980415 ChemDiv1_022395 OCCNCC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J22 compound treatment 683912.0 227000.0 0.47 665050.0 212000.0 0.46 0.656 0.9999 1980416 ChemDiv1_022396 CCCC(=O)N1c2ccc(OC)cc2C3=C(SC(=C(C(=O)OC)C43SC(=C(S4)C(=O)OC)C(=O)OC)C(=O)OC)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J23 mock treatment 686247.0 230000.0 0.47 676970.0 224000.0 0.48 0.6776 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 J24 mock treatment 231005.0 -226000.0 -0.47 203663.0 -250000.0 -0.54 -0.7113 -0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K01 compound treatment 667631.0 211000.0 0.44 607083.0 154000.0 0.33 0.5435 0.9912 1980417 ChemDiv1_022397 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5ccc(C)cc5)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K02 compound treatment 671552.0 215000.0 0.44 629172.0 176000.0 0.38 0.583 0.9971 1426138 ChemDiv1_022398 OC(=O)COc1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K03 compound treatment 692361.0 236000.0 0.49 668181.0 215000.0 0.47 0.6731 0.9997 1627579 ChemDiv1_022399 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(I)cc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K04 compound treatment 672592.0 216000.0 0.45 682133.0 229000.0 0.5 0.6656 0.9986 1980418 ChemDiv1_022400 [O-][N+](=O)c1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K05 compound treatment 675412.0 219000.0 0.45 690533.0 237000.0 0.51 0.6826 0.9979 1225984 ChemDiv1_022401 COc1cc(ccc1OCc2ccc(Cl)cc2)C3C4=C(CC(C)(C)CC4=O)NC5=C3C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K06 compound treatment 679329.0 223000.0 0.46 662031.0 209000.0 0.45 0.6447 1.0 1253208 ChemDiv1_022402 Cc1nn2c3ccccc3n(CC(=O)C(C)(C)C)c2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K07 compound treatment 706130.0 249000.0 0.52 695269.0 242000.0 0.52 0.7346 1.0 1697083 ChemDiv1_022403 Cc1ccc(cc1)C2(CC2C(=O)Nc3cccc(Cl)c3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K08 compound treatment 690770.0 234000.0 0.48 677278.0 224000.0 0.48 0.6847 1.0 1451459 ChemDiv1_022404 O=C(CN1C(=O)c2ccccc2C1=O)N3CCCc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K09 compound treatment 724536.0 268000.0 0.55 702562.0 249000.0 0.54 0.7727 0.9999 1562099 ChemDiv1_022405 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(Cl)c5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K10 compound treatment 698813.0 242000.0 0.5 650965.0 198000.0 0.43 0.6562 0.997 1188336 ChemDiv1_022406 CCOC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K11 compound treatment 727403.0 271000.0 0.56 675828.0 223000.0 0.48 0.7359 0.9973 1407409 ChemDiv1_022407 Fc1ccccc1N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K12 compound treatment 675960.0 219000.0 0.45 667156.0 214000.0 0.46 0.6476 0.9999 1266939 ChemDiv1_022408 CCOC(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K13 compound treatment 723114.0 266000.0 0.55 684164.0 231000.0 0.5 0.7424 0.9989 1375867 ChemDiv1_022409 Cc1ccc(NC(=O)C2CC2(c3ccccc3C)c4ccccc4C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K14 compound treatment 713908.0 257000.0 0.53 661146.0 208000.0 0.45 0.6938 0.9966 1288099 ChemDiv1_022410 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CCN(CCO)CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K15 compound treatment 753818.0 297000.0 0.61 678440.0 225000.0 0.49 0.7785 0.9935 1390549 ChemDiv1_022411 CC1(C2C(C3c4ccccc41)C(=O)N(CC=C)C2=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K16 compound treatment 681141.0 225000.0 0.46 664904.0 212000.0 0.46 0.6517 1.0 1980419 ChemDiv1_022412 Clc1ccc(cc1)C(CC(=O)c2ccco2)SCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K17 compound treatment 695158.0 239000.0 0.49 718014.0 265000.0 0.57 0.7534 0.9971 1363288 ChemDiv1_022413 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(C)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K18 compound treatment 673441.0 217000.0 0.45 682519.0 229000.0 0.5 0.6674 0.9987 1980420 ChemDiv1_022414 Cc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K19 compound treatment 692540.0 236000.0 0.49 708140.0 255000.0 0.55 0.7345 0.9981 1980421 ChemDiv1_022415 Cc1c(N(CC(=O)N/N=C/c2ccccc2Cl)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K20 compound treatment 1373781.0 917000.0 1.89 1599942.0 1150000.0 2.48 3.0938 0.9911 1980422 ChemDiv1_022416 O=C(CSc1ccc2-c3ccccc3C(=O)c4cccc1c42)Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K21 compound treatment 667848.0 211000.0 0.44 704944.0 252000.0 0.54 0.6936 0.9939 1397168 ChemDiv1_022417 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K22 compound treatment 633517.0 177000.0 0.37 694728.0 242000.0 0.52 0.6278 0.9846 1601344 ChemDiv1_022418 Nc1ccc(cc1)c2nnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K23 mock treatment 821916.0 365000.0 0.75 672760.0 220000.0 0.48 0.8692 0.9752 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 K24 mock treatment 208480.0 -248000.0 -0.51 222355.0 -231000.0 -0.5 -0.7155 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L01 compound treatment 682412.0 226000.0 0.47 630150.0 177000.0 0.38 0.6004 0.9952 1288365 ChemDiv1_022419 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L02 compound treatment 669665.0 213000.0 0.44 638695.0 185000.0 0.4 0.5948 0.999 1484813 ChemDiv1_022420 CC1CCc2c(C(=O)N)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L03 compound treatment 712217.0 256000.0 0.53 660069.0 207000.0 0.45 0.6897 0.9967 1277786 ChemDiv1_022421 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N(C)C3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L04 compound treatment 680301.0 224000.0 0.46 628083.0 175000.0 0.38 0.5941 0.9951 1980423 ChemDiv1_022422 CC1(C)C2(CN3CC1(CN(C2)C3c4cccc(c4)[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L05 compound treatment 711340.0 255000.0 0.53 660436.0 207000.0 0.45 0.6889 0.9969 1394791 ChemDiv1_022423 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N3CCC(C)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L06 compound treatment 683514.0 227000.0 0.47 661404.0 208000.0 0.45 0.6498 0.9998 1146463 ChemDiv1_022424 CCOC(=O)c1c(NC(=O)c2ccc(Cc3ccc(C)cc3)o2)sc4CC(CCc14)(C#N)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L07 compound treatment 695604.0 239000.0 0.49 683156.0 230000.0 0.5 0.7007 1.0 1980424 ChemDiv1_022425 CCN(CC)c1ccn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L08 compound treatment 717464.0 261000.0 0.54 674519.0 221000.0 0.48 0.7194 0.9983 1980425 ChemDiv1_022426 CSc1nnc2n(c3ccccc3)c(=O)c4c(C)c(C)sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L09 compound treatment 722324.0 266000.0 0.55 678297.0 225000.0 0.49 0.7323 0.9983 1254461 ChemDiv1_022427 COc1ccccc1C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L10 compound treatment 709938.0 253000.0 0.52 667631.0 214000.0 0.46 0.6979 0.9982 1980426 ChemDiv1_022428 COC(=O)c1cccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccc(Br)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L11 compound treatment 733168.0 277000.0 0.57 686266.0 233000.0 0.5 0.7603 0.9981 1297376 ChemDiv1_022429 O=c1cccc2C3CC(CN(C3)C(=S)NCc4ccccc4)Cn21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L12 compound treatment 681757.0 225000.0 0.46 689068.0 236000.0 0.51 0.6896 0.9989 1980427 ChemDiv1_022430 COc1ccc(/C=C(\NC(=O)c2ccc(Br)cc2)/C(=O)NCc3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L13 compound treatment 725822.0 269000.0 0.56 660426.0 207000.0 0.45 0.7101 0.9943 1693653 ChemDiv1_022431 CC12COC3(CC2CCC13C)C(=O)NCCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L14 compound treatment 703244.0 247000.0 0.51 710518.0 257000.0 0.56 0.7538 0.999 1980428 ChemDiv1_022432 COc1ccc(NC(=O)/C(=C/c2ccc3OCOc3c2)/NC(=O)c4ccccc4OC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L15 compound treatment 729526.0 273000.0 0.56 714442.0 261000.0 0.57 0.7981 1.0 1633219 ChemDiv1_022433 CC12COC3(CC2CCC13C)C(=O)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L16 compound treatment 694213.0 238000.0 0.49 688596.0 235000.0 0.51 0.707 0.9998 1980429 ChemDiv1_022434 COc1ccc(cc1OC)C2(CNC(=O)/C=C(/C)\c3ccccc3)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L17 compound treatment 718810.0 262000.0 0.54 714950.0 262000.0 0.57 0.7833 0.9997 1980430 ChemDiv1_022435 Cc1cc(C)c(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L18 compound treatment 689975.0 233000.0 0.48 661051.0 208000.0 0.45 0.6587 0.9994 1919839 ChemDiv1_022436 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccc(OC)cc4NC3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L19 compound treatment 699375.0 243000.0 0.5 685485.0 232000.0 0.5 0.7098 1.0 1153667 ChemDiv1_022437 Cc1ccc(Nc2ccc3n(C)c(=O)cc4-c5ccccc5C(=O)c2c43)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L20 compound treatment 642210.0 186000.0 0.38 655804.0 203000.0 0.44 0.5809 0.9977 1124503 ChemDiv1_022438 Cc1ccc(cc1)n2sc3c(-c4ccccc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L21 compound treatment 690642.0 234000.0 0.48 690424.0 237000.0 0.51 0.7046 0.9995 1980431 ChemDiv1_022439 OCCNCC(O)Cn1c2ccccc2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L22 compound treatment 669326.0 213000.0 0.44 695624.0 242000.0 0.52 0.6815 0.9961 1199105 ChemDiv1_022440 COc1cccc(c1)C(=O)N2c3ccccc3Sc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L23 mock treatment 706259.0 250000.0 0.52 682495.0 229000.0 0.5 0.7153 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 L24 mock treatment 255089.0 -202000.0 -0.42 232711.0 -221000.0 -0.48 -0.6317 -0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M01 compound treatment 657228.0 201000.0 0.41 611181.0 158000.0 0.34 0.5346 0.9955 1980432 ChemDiv1_022441 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccccc4OC(=O)c5ccc(Cl)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M02 compound treatment 663806.0 207000.0 0.43 626034.0 173000.0 0.37 0.5669 0.9978 1146426 ChemDiv1_022442 CC(=O)Nc1ccc(cc1Cl)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M03 compound treatment 706435.0 250000.0 0.52 650293.0 197000.0 0.43 0.6663 0.9956 1167590 ChemDiv1_022443 COC(=O)c1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M04 compound treatment 645915.0 189000.0 0.39 638058.0 185000.0 0.4 0.5592 0.9999 1980433 ChemDiv1_022444 COc1ccc(cc1)C2NC(=S)NC(=C2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M05 compound treatment 717208.0 261000.0 0.54 674670.0 221000.0 0.48 0.7193 0.9983 1678526 ChemDiv1_022445 Cc1ccc(COc2ccc(cc2)C3C4=C(CC(C)(C)CC4=O)NC5=C3C(=O)CC(C)(C)C5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M06 compound treatment 682616.0 226000.0 0.47 670703.0 217000.0 0.47 0.6627 1.0 1980434 ChemDiv1_022446 COc1ccccc1NNC(=O)C(O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M07 compound treatment 738729.0 282000.0 0.58 685193.0 232000.0 0.5 0.7668 0.9973 1205671 ChemDiv1_022447 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccc(F)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M08 compound treatment 675047.0 218000.0 0.45 672105.0 219000.0 0.47 0.6538 0.9997 1670990 ChemDiv1_022448 Cc1ccc(cc1)C2(CC3CC4CC(C3)(C2)C(=O)NC(C)(C)CO)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M09 compound treatment 712937.0 256000.0 0.53 670405.0 217000.0 0.47 0.7065 0.9983 1779066 ChemDiv1_022449 Cc1c(Cl)cccc1N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M10 compound treatment 660625.0 204000.0 0.42 625372.0 172000.0 0.37 0.5612 0.9981 1980435 ChemDiv1_022450 CCCCOC(=O)COc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M11 compound treatment 726549.0 270000.0 0.56 690212.0 237000.0 0.51 0.7567 0.9991 1781512 ChemDiv1_022451 CC1(C2C(C3c4ccccc41)C(=O)N(Cc5ccc(F)cc5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M12 compound treatment 664382.0 208000.0 0.43 592222.0 139000.0 0.3 0.516 0.985 1980436 ChemDiv1_022452 CCCCOC(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M13 compound treatment 727717.0 271000.0 0.56 642744.0 190000.0 0.41 0.6858 0.9883 1359546 ChemDiv1_022453 CCc1ccc(cc1)C2(CC2C(=O)Nc3ccc(Cl)cc3)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M14 compound treatment 676102.0 219000.0 0.45 610223.0 157000.0 0.34 0.5607 0.99 1736571 ChemDiv1_022454 O=C(CN1C(=O)c2ccccc2C1=O)Nc3sc4CCCCc4c3c5nc6ccccc6s5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M15 compound treatment 700009.0 243000.0 0.5 685466.0 232000.0 0.5 0.7107 1.0 1589662 ChemDiv1_022455 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(I)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M16 compound treatment 687610.0 231000.0 0.48 732788.0 280000.0 0.61 0.765 0.993 1980437 ChemDiv1_022456 OCCSC(CC(=O)c1ccco1)c2ccc(OC(F)F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M17 compound treatment 714907.0 258000.0 0.53 723629.0 270000.0 0.59 0.7909 0.9989 1421434 ChemDiv1_022457 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(Cc5ccco5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M18 compound treatment 691116.0 234000.0 0.48 696398.0 243000.0 0.53 0.7145 0.9991 1980438 ChemDiv1_022458 C1Oc2ccc(cc2O1)C3CC(=Nc4ccccc4S3)c5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M19 compound treatment 691299.0 235000.0 0.48 699745.0 247000.0 0.53 0.7198 0.9988 1444839 ChemDiv1_022459 Cc1ccc(Nc2nc3nonc3n4cnnc24)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M20 compound treatment 3080139.0 2620000.0 5.42 3407474.0 2950000.0 6.39 8.3508 0.9966 1980439 ChemDiv1_022460 COCCCNC(=O)CSc1ccc2-c3ccccc3C(=O)c4cccc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M21 compound treatment 685057.0 228000.0 0.47 753247.0 300000.0 0.65 0.7926 0.9876 1569764 ChemDiv1_022461 COc1ccc(cc1)C2(Oc3ccc4ccc(OC(=O)C(C)C)cc4c3C=C2)c5ccccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M22 compound treatment 660816.0 204000.0 0.42 677660.0 224000.0 0.49 0.6415 0.9975 1980440 ChemDiv1_022462 CCOc1cc(/C=C(\C#N)/c2nnc3CCCCCn23)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M23 mock treatment 707398.0 251000.0 0.52 667553.0 214000.0 0.46 0.6941 0.9985 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 M24 mock treatment 360801.0 -95800.0 -0.2 372550.0 -80700.0 -0.17 -0.2633 -0.9981 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N01 compound treatment 672896.0 216000.0 0.45 612446.0 159000.0 0.34 0.5594 0.9918 1304628 ChemDiv1_022463 Cc1ccccc1n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N02 compound treatment 705511.0 249000.0 0.51 620922.0 168000.0 0.36 0.62 0.9855 1328168 ChemDiv1_022464 CCCC1CCc2c(C(=O)N)c(NC(=O)c3c(C)onc3c4c(Cl)cccc4Cl)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N03 compound treatment 708260.0 252000.0 0.52 656455.0 203000.0 0.44 0.6783 0.9966 1391485 ChemDiv1_022465 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)N3CCCC(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N04 compound treatment 649239.0 193000.0 0.4 621230.0 168000.0 0.36 0.5383 0.999 1307172 ChemDiv1_022466 CC(C)C1(CN2CC3(CN(C1)C2c4ccc(O)cc4O)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N05 compound treatment 672090.0 215000.0 0.44 668987.0 216000.0 0.47 0.6447 0.9997 1380600 ChemDiv1_022467 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N(C)Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N06 compound treatment 702046.0 245000.0 0.51 622786.0 170000.0 0.37 0.6177 0.9875 1567808 ChemDiv1_022468 Cc1cc(Cl)ccc1OCC(=O)Nc2sc3CCCCCc3c2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N07 compound treatment 714336.0 258000.0 0.53 649453.0 196000.0 0.42 0.6765 0.9938 1522341 ChemDiv1_022469 CC(=C)COc1ccc2c3CCCCc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N08 compound treatment 700894.0 244000.0 0.5 663742.0 211000.0 0.46 0.6787 0.9987 1980441 ChemDiv1_022470 CC(C)Sc1nnc2n(c3ccccc3)c(=O)c4c(C)c(C)sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N09 compound treatment 741909.0 285000.0 0.59 683346.0 230000.0 0.5 0.7686 0.9965 1980442 ChemDiv1_022471 CCCc1nnc2SCC(=Nn12)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N10 compound treatment 675000.0 218000.0 0.45 673836.0 221000.0 0.48 0.6564 0.9996 1980443 ChemDiv1_022472 COc1ccccc1C(=O)N/C(=C/c2ccc3OCOc3c2)/C(=O)Nc4cccc(c4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N11 compound treatment 745457.0 289000.0 0.6 694238.0 241000.0 0.52 0.7905 0.9978 1702873 ChemDiv1_022473 O=c1cccc2C3CC(CN(C3)C(=S)NCCc4ccccc4)Cn21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N12 compound treatment 701556.0 245000.0 0.51 662117.0 209000.0 0.45 0.6772 0.9984 1980444 ChemDiv1_022474 [O-][N+](=O)c1cccc(/C=C(\NC(=O)c2ccc(Br)cc2)/C(=O)NCc3ccco3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N13 compound treatment 709723.0 253000.0 0.52 675160.0 222000.0 0.48 0.7091 0.9991 1357539 ChemDiv1_022475 CN1CCN(CC1)C(=O)C23CC4CCC3(C)C4(C)CO2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N14 compound treatment 725250.0 269000.0 0.55 671805.0 219000.0 0.47 0.7266 0.9969 1980445 ChemDiv1_022476 COc1ccccc1C(=O)N/C(=C\c2ccc3OCOc3c2)/C(=O)Nc4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N15 compound treatment 724210.0 268000.0 0.55 680243.0 227000.0 0.49 0.738 0.9983 1980446 ChemDiv1_022477 CC12COC3(CC2CCC13C)C(=O)Nc4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N16 compound treatment 678116.0 221000.0 0.46 647688.0 194000.0 0.42 0.6209 0.9991 1406283 ChemDiv1_022478 COc1ccc(CC(=O)NCC2(CCCC2)c3ccc(OC)c(OC)c3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N17 compound treatment 723488.0 267000.0 0.55 693675.0 240000.0 0.52 0.7575 0.9996 1445750 ChemDiv1_022479 COC(=O)c1ccc(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N18 compound treatment 678254.0 222000.0 0.46 663929.0 211000.0 0.46 0.646 1.0 1980447 ChemDiv1_022480 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccc(C)cc4NC3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N19 compound treatment 731450.0 275000.0 0.57 706766.0 254000.0 0.55 0.7892 0.9999 1980448 ChemDiv1_022481 CC(=O)c1c2-c3ccccc3C(=O)c4c(Br)ccc(n(C)c1=O)c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N20 compound treatment 662353.0 206000.0 0.42 682596.0 229000.0 0.5 0.6513 0.997 1678880 ChemDiv1_022482 Fc1ccc(CCN2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N21 compound treatment 679300.0 223000.0 0.46 713507.0 260000.0 0.56 0.7234 0.9949 1467072 ChemDiv1_022483 CC(C)(C)NCC(O)Cn1c2ccccc2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N22 compound treatment 659190.0 203000.0 0.42 639664.0 186000.0 0.4 0.581 0.9998 1469311 ChemDiv1_022484 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(F)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N23 mock treatment 657273.0 201000.0 0.41 644884.0 192000.0 0.41 0.5862 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 N24 mock treatment 247183.0 -209000.0 -0.43 375880.0 -77300.0 -0.17 -0.4241 -0.9147 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O01 compound treatment 676681.0 220000.0 0.45 587310.0 134000.0 0.29 0.5264 0.9766 1980449 ChemDiv1_022485 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5cccc(c5)[N+](=O)[O-])cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O02 compound treatment 654235.0 198000.0 0.41 605677.0 152000.0 0.33 0.5218 0.9945 1980450 ChemDiv1_022486 Brc1ccc(cc1)C2=Nn3c(nnc3SC2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O03 compound treatment 661745.0 205000.0 0.42 642210.0 189000.0 0.41 0.5886 0.9999 1518572 ChemDiv1_022487 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(Cl)cc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O04 compound treatment 693485.0 237000.0 0.49 614834.0 162000.0 0.35 0.5931 0.9865 1706792 ChemDiv1_022488 CCN(CC)CCn1c2ccccc2n3nc(C)c(=O)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O05 compound treatment 727036.0 270000.0 0.56 641424.0 188000.0 0.41 0.6827 0.988 1945569 ChemDiv1_022489 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O06 compound treatment 679807.0 223000.0 0.46 624490.0 171000.0 0.37 0.5879 0.9942 1948939 ChemDiv1_022490 C(Sc1nnc(c2ccncc2)n1c3ccccc3)/C=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O07 compound treatment 692848.0 236000.0 0.49 633846.0 181000.0 0.39 0.6212 0.994 1545099 ChemDiv1_022491 Cc1cccc(c1)C2(CC2C(=O)Nc3cccc(Cl)c3C)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O08 compound treatment 682041.0 225000.0 0.47 627335.0 174000.0 0.38 0.5955 0.9945 1980451 ChemDiv1_022492 CCOC(=O)/C(=C\N1CCc2ccccc2C1)/C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O09 compound treatment 676766.0 220000.0 0.45 667553.0 214000.0 0.46 0.6494 0.9999 1781269 ChemDiv1_022493 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(c5)[N+](=O)[O-])c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O10 compound treatment 647080.0 190000.0 0.39 609984.0 157000.0 0.34 0.5179 0.9973 1328351 ChemDiv1_022494 O=C(COc1ccc2c3CCCCc3c(=O)oc2c1)OCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O11 compound treatment 677231.0 221000.0 0.46 669011.0 216000.0 0.47 0.6523 0.9999 1625620 ChemDiv1_022495 COc1ccc(CCN2C(=O)C3C(C2=O)C4(C)c5ccccc5C3c6ccccc64)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O12 compound treatment 653070.0 196000.0 0.41 613684.0 160000.0 0.35 0.5323 0.997 1442838 ChemDiv1_022496 Cc1cc(OCC(=O)OCc2ccccc2)c3c4CCCCc4c(=O)oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O13 compound treatment 708613.0 252000.0 0.52 652099.0 199000.0 0.43 0.6722 0.9956 1980452 ChemDiv1_022497 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O14 compound treatment 752883.0 296000.0 0.61 727848.0 275000.0 0.59 0.8527 0.9999 1283928 ChemDiv1_022498 CCN1C(=O)c2cccc3c(NC(=O)c4ccc(cc4)S(=O)(=O)N5CC(C)CC(C)C5)ccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O15 compound treatment 683180.0 227000.0 0.47 676471.0 223000.0 0.48 0.6724 0.9999 1345842 ChemDiv1_022499 Cc1ccc(C)c(NC(=O)C2CC2(c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O16 compound treatment 620654.0 164000.0 0.34 623159.0 170000.0 0.37 0.4995 0.9991 1980453 ChemDiv1_022500 FC(F)Oc1ccc(cc1)C2CC(=Nc3ccccc3S2)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O17 compound treatment 682094.0 225000.0 0.47 673291.0 220000.0 0.48 0.6659 0.9999 1980454 ChemDiv1_022501 Cc1c(N(CC(=O)N/N=C/c2ccccc2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O18 compound treatment 633533.0 177000.0 0.37 631325.0 178000.0 0.39 0.5308 0.9996 1980455 ChemDiv1_022502 Fc1ccc(cc1)c2nnc3ccccn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O19 compound treatment 676604.0 220000.0 0.45 654514.0 201000.0 0.44 0.6292 0.9998 1507013 ChemDiv1_022503 Cn1c(Br)nc2n(C)c(=O)n(Cc3ccccc3F)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O20 compound treatment 648863.0 192000.0 0.4 634220.0 181000.0 0.39 0.5576 1.0 1949056 ChemDiv1_022504 C(Sc1nnc(c2ccco2)n1c3ccccc3)/C=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O21 compound treatment 663888.0 207000.0 0.43 654270.0 201000.0 0.44 0.6102 1.0 1293456 ChemDiv1_022505 COc1ccc2N(C)C3(Oc4c(cc5ccccc5c4N=C3)C(=O)N6CCCCC6)C(C)(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O22 compound treatment 646906.0 190000.0 0.39 620080.0 167000.0 0.36 0.5331 0.9991 1980456 ChemDiv1_022506 CCOc1ccc(cc1)C2=Nn3c(nnc3SC2)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O23 mock treatment 651857.0 195000.0 0.4 631481.0 178000.0 0.39 0.5578 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 O24 mock treatment 260063.0 -197000.0 -0.41 137021.0 -316000.0 -0.68 -0.7708 -0.9689 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P01 compound treatment 666654.0 210000.0 0.43 583292.0 130000.0 0.28 0.5056 0.9781 1980457 ChemDiv1_022507 Brc1ccc(cc1)C2=Nn3cnnc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P02 compound treatment 663331.0 207000.0 0.43 608403.0 155000.0 0.34 0.5392 0.993 1571355 ChemDiv1_022508 COC(=O)c1c(NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)sc4CCCCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P03 compound treatment 687615.0 231000.0 0.48 619618.0 166000.0 0.36 0.5918 0.9904 1712111 ChemDiv1_022509 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)N3CCC(C)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P04 compound treatment 645094.0 188000.0 0.39 604107.0 151000.0 0.33 0.506 0.9962 1980458 ChemDiv1_022510 COc1ccc(/C=C/C(=O)NCC2(CCCC2)c3ccccc3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P05 compound treatment 676471.0 220000.0 0.45 605848.0 153000.0 0.33 0.5545 0.9878 1153166 ChemDiv1_022511 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)N3CCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P06 compound treatment 691216.0 235000.0 0.48 622902.0 170000.0 0.37 0.6021 0.9907 1675563 ChemDiv1_022512 Brc1cccc(c1)n2c(=O)c3c([nH]c2=S)-c4ccccc4CC53CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P07 compound treatment 668196.0 212000.0 0.44 603964.0 151000.0 0.33 0.5395 0.9897 1267141 ChemDiv1_022513 CC(C)OC(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P08 compound treatment 659758.0 203000.0 0.42 589574.0 136000.0 0.3 0.5052 0.9852 1980459 ChemDiv1_022514 OC(=O)c1ccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P09 compound treatment 668941.0 212000.0 0.44 606012.0 153000.0 0.33 0.5438 0.9904 1980460 ChemDiv1_022515 Cc1ccc(cc1)C2=Nn3cnnc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P10 compound treatment 694433.0 238000.0 0.49 614458.0 161000.0 0.35 0.5939 0.986 1980461 ChemDiv1_022516 COC(=O)c1cccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P11 compound treatment 673187.0 217000.0 0.45 610008.0 157000.0 0.34 0.5561 0.9908 1526842 ChemDiv1_022517 O=C(Nc1ccccc1)N2CC3CC(C2)c4cccc(=O)n4C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P12 compound treatment 696332.0 240000.0 0.49 600790.0 148000.0 0.32 0.5757 0.9776 1980462 ChemDiv1_022518 [O-][N+](=O)c1cccc(/C=C(\NC(=O)c2ccco2)/C(=O)NCc3ccco3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P13 compound treatment 677207.0 221000.0 0.46 597480.0 144000.0 0.31 0.5428 0.9831 1742842 ChemDiv1_022519 CC12COC3(CC2CCC13C)C(=O)NC4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P14 compound treatment 674769.0 218000.0 0.45 619233.0 166000.0 0.36 0.5725 0.9937 1980463 ChemDiv1_022520 COc1ccccc1C(=O)N/C(=C\c2ccc3OCOc3c2)/C(=O)Nc4ccc(cc4)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P15 compound treatment 683171.0 227000.0 0.47 610069.0 157000.0 0.34 0.5707 0.9876 1503636 ChemDiv1_022521 CC12COC3(CC2CCC13C)C(=O)Nc4ccccc4Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P16 compound treatment 684401.0 228000.0 0.47 643327.0 190000.0 0.41 0.6234 0.9978 1589716 ChemDiv1_022522 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P17 compound treatment 673403.0 217000.0 0.45 640679.0 187000.0 0.41 0.6033 0.9988 1426874 ChemDiv1_022523 CC1(C)C2(C)CCC1(OC2=O)C(=O)Nc3ccc(OC(=O)C4(CCC5(C)C(=O)O4)C5(C)C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P18 compound treatment 641292.0 185000.0 0.38 645349.0 192000.0 0.42 0.5636 0.9991 1980464 ChemDiv1_022524 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C)c3ccc(C)cc23)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P19 compound treatment 645910.0 189000.0 0.39 631127.0 178000.0 0.39 0.5486 1.0 1402279 ChemDiv1_022525 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P20 compound treatment 640238.0 184000.0 0.38 606328.0 153000.0 0.33 0.5023 0.9978 1429803 ChemDiv1_022526 Clc1ccc(cc1)C2OC3(C4C2C(=O)N(C5CCCCC5)C4=O)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P21 compound treatment 670810.0 214000.0 0.44 607148.0 154000.0 0.33 0.5482 0.9903 1980465 ChemDiv1_022527 CCCCCCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P22 compound treatment 647579.0 191000.0 0.39 621550.0 168000.0 0.36 0.5364 0.9992 1441172 ChemDiv1_022528 Fc1cccc(c1)C(=O)N2c3ccccc3Sc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P23 mock treatment 650934.0 194000.0 0.4 585956.0 133000.0 0.29 0.4868 0.9866 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.650 P24 mock treatment 119460.0 -337000.0 -0.7 465235.0 12000.0 0.03 -0.4738 -0.6802 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A01 compound treatment 656303.0 180000.0 0.37 594532.0 118000.0 0.26 0.4435 0.9832 1721668 ChemDiv1_022881 CC(C)Oc1ccccc1C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A02 compound treatment 659249.0 183000.0 0.38 609652.0 133000.0 0.29 0.471 0.9911 1980466 ChemDiv1_022882 COc1ccc(cc1)n2nnnc2C3(CCCCC3)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A03 compound treatment 677274.0 201000.0 0.42 602410.0 126000.0 0.27 0.4862 0.9792 1370283 ChemDiv1_022883 COc1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A04 compound treatment 696669.0 220000.0 0.46 611589.0 135000.0 0.29 0.5286 0.9771 1939806 ChemDiv1_022884 Oc1ccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A05 compound treatment 720555.0 244000.0 0.5 601573.0 125000.0 0.27 0.5481 0.9574 1136727 ChemDiv1_022885 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A06 compound treatment 724547.0 248000.0 0.51 626293.0 150000.0 0.32 0.5918 0.9756 1980467 ChemDiv1_022886 CC(=O)/C(=C/1\NC(C)(C)Cc2cc(C)c(C)cc12)/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A07 compound treatment 719910.0 244000.0 0.5 663199.0 187000.0 0.4 0.6415 0.9941 1576534 ChemDiv1_022887 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(F)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A08 compound treatment 718131.0 242000.0 0.5 657139.0 181000.0 0.39 0.6296 0.9927 1980468 ChemDiv1_022888 Clc1ccccc1C2NC(=S)NC(=C2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A09 compound treatment 732422.0 256000.0 0.53 654883.0 178000.0 0.39 0.647 0.988 1253777 ChemDiv1_022889 COC(=O)C(Cc1ccccc1)NC(=O)c2cc3C(=O)CC(C)(C)Cc3n(c4ccccc4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A10 compound treatment 1.4939151E7 1.45E7 29.86 1.2814622E7 1.23E7 26.7 39.9943 0.9985 1980469 ChemDiv1_022890 CN1C=C/C(=C\C=C\2/C=Nc3ccccc23)/c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A11 compound treatment 735285.0 259000.0 0.53 651369.0 175000.0 0.38 0.6458 0.9857 1596319 ChemDiv1_022891 COc1ccccc1N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A12 compound treatment 732989.0 257000.0 0.53 658614.0 182000.0 0.39 0.6536 0.9894 1433410 ChemDiv1_022892 Cc1cc(N2CCNCC2)c3ccccc3n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A13 compound treatment 741146.0 265000.0 0.55 646646.0 170000.0 0.37 0.6471 0.9815 1980470 ChemDiv1_022893 Cc1ccc(cc1)S(=O)(=O)N2c3ccccc3-c4ccccc4S2(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A14 compound treatment 758993.0 283000.0 0.58 656428.0 180000.0 0.39 0.6882 0.9806 1980471 ChemDiv1_022894 COc1ccc(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A15 compound treatment 733741.0 258000.0 0.53 658179.0 182000.0 0.39 0.654 0.989 1589834 ChemDiv1_022895 Cc1ccc(C)c2-c3ccccc3S(=O)(=O)N(c12)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A16 compound treatment 697828.0 222000.0 0.46 635080.0 159000.0 0.34 0.5662 0.99 1950669 ChemDiv1_022896 CC1=C(C(CC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OCCCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A17 compound treatment 709426.0 233000.0 0.48 634729.0 158000.0 0.34 0.5826 0.9861 1324410 ChemDiv1_022897 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A18 compound treatment 683026.0 207000.0 0.43 600858.0 124000.0 0.27 0.4922 0.9753 1148880 ChemDiv1_022898 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(Cl)cc4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A19 compound treatment 704290.0 228000.0 0.47 631626.0 155000.0 0.34 0.5704 0.9863 1256912 ChemDiv1_022899 COc1cc(OC)c(c2nc3c([nH]2)c4ccccc4c5ccccc35)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A20 compound treatment 685934.0 210000.0 0.43 644100.0 168000.0 0.36 0.5627 0.9961 1980472 ChemDiv1_022900 CCOC(=O)C1C(NC(=S)NC1(O)C(F)(F)F)c2ccc(Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A21 compound treatment 694178.0 218000.0 0.45 632761.0 156000.0 0.34 0.5573 0.9901 1980473 ChemDiv1_022901 CC(=O)Nc1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A22 compound treatment 692078.0 216000.0 0.45 616712.0 140000.0 0.3 0.5297 0.9825 1474545 ChemDiv1_022902 COc1ccc(cc1)C2CC(=Nc3ccccc3N2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A23 mock treatment 637463.0 161000.0 0.33 607007.0 131000.0 0.28 0.4351 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 A24 mock treatment 210805.0 -265000.0 -0.55 246890.0 -230000.0 -0.5 -0.7388 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B01 compound treatment 685652.0 209000.0 0.43 604414.0 128000.0 0.28 0.5015 0.9768 1623554 ChemDiv1_022903 Cc1cccc(c1)n2c(=O)c3c([nH]c2=S)-c4ccccc4CC53CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B02 compound treatment 663728.0 188000.0 0.39 621882.0 145000.0 0.31 0.4962 0.9947 1289495 ChemDiv1_022904 O=C1Nc2c(cc(c3cccc1c23)S(=O)(=O)Nc4ccccc4)S(=O)(=O)Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B03 compound treatment 732055.0 256000.0 0.53 668520.0 192000.0 0.42 0.6674 0.993 1980474 ChemDiv1_022905 [O-][N+](=O)c1ccc(CC(=O)N2CCCc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B04 compound treatment 710837.0 235000.0 0.48 647875.0 171000.0 0.37 0.6048 0.9913 1980475 ChemDiv1_022906 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B05 compound treatment 760273.0 284000.0 0.59 688332.0 212000.0 0.46 0.7389 0.9926 1294021 ChemDiv1_022907 CC1(CN2CC3(C)CN(C1)C2c4cccc(Br)c4)C3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B06 compound treatment 728397.0 252000.0 0.52 664894.0 188000.0 0.41 0.6565 0.9927 1980476 ChemDiv1_022908 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B07 compound treatment 766505.0 290000.0 0.6 693047.0 217000.0 0.47 0.7552 0.9926 1980477 ChemDiv1_022909 CCCOc1ccccc1N=c2ssc3c2-c4cc(OCC)ccc4NC3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B08 compound treatment 774850.0 299000.0 0.62 695509.0 219000.0 0.47 0.7711 0.9916 1980478 ChemDiv1_022910 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B09 compound treatment 776096.0 300000.0 0.62 712274.0 236000.0 0.51 0.7986 0.9954 1262065 ChemDiv1_022911 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2ccc3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B10 compound treatment 747281.0 271000.0 0.56 691696.0 215000.0 0.47 0.7251 0.9958 1980479 ChemDiv1_022912 CCc1ccc(cc1)S(=O)(=O)N(C(=O)c2ccc(C)cc2)c3ccc4oc(C)c(C(=O)C)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B11 compound treatment 746027.0 270000.0 0.56 707943.0 231000.0 0.5 0.7481 0.9986 1288286 ChemDiv1_022913 CCOC(=O)c1c(C)n(c2ccc(NS(=O)(=O)c3ccc(OCC)cc3)cc12)S(=O)(=O)c4ccc(OCC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B12 compound treatment 815125.0 339000.0 0.7 670336.0 194000.0 0.42 0.7914 0.9701 1720935 ChemDiv1_022914 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B13 compound treatment 766998.0 291000.0 0.6 693869.0 217000.0 0.47 0.7572 0.9927 1686148 ChemDiv1_022915 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c4C(=O)CCCc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B14 compound treatment 732694.0 256000.0 0.53 683791.0 207000.0 0.45 0.6917 0.9966 1642878 ChemDiv1_022916 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B15 compound treatment 755909.0 280000.0 0.58 704990.0 228000.0 0.49 0.758 0.997 1524958 ChemDiv1_022917 Cc1ccc(c(C)c1)S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B16 compound treatment 749748.0 274000.0 0.56 687213.0 211000.0 0.46 0.7218 0.9944 1609941 ChemDiv1_022918 CCCC(=O)N(c1ccc2oc(C)c(C(=O)OCC)c2c1)S(=O)(=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B17 compound treatment 728651.0 252000.0 0.52 713180.0 237000.0 0.51 0.7307 1.0 1980480 ChemDiv1_022919 CC1CCc2oc3ccc(NS(=O)(=O)c4cccc(c4)[N+](=O)[O-])cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B18 compound treatment 732482.0 256000.0 0.53 688086.0 212000.0 0.46 0.6979 0.9974 1864675 ChemDiv1_022920 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B19 compound treatment 736642.0 260000.0 0.54 694759.0 218000.0 0.47 0.7142 0.9979 1603112 ChemDiv1_022921 CC1CCc2c(C1)oc3ccc(NS(=O)(=O)c4ccccc4)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B20 compound treatment 716526.0 240000.0 0.5 657054.0 181000.0 0.39 0.6271 0.993 1980481 ChemDiv1_022922 CCCC(=O)N(c1ccc2oc(C)c(C(=O)OC)c2c1)S(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B21 compound treatment 753688.0 277000.0 0.57 682731.0 206000.0 0.45 0.7207 0.9924 1316600 ChemDiv1_022923 CC1CCc2c(C1)oc3c2cc(NS(=O)(=O)c4ccc(Cl)cc4)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B22 compound treatment 708239.0 232000.0 0.48 665968.0 189000.0 0.41 0.6287 0.997 1933503 ChemDiv1_022924 CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc3COC(Cc13)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B23 mock treatment 693092.0 217000.0 0.45 648310.0 172000.0 0.37 0.5796 0.9957 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 B24 mock treatment 231675.0 -245000.0 -0.5 235434.0 -241000.0 -0.52 -0.7259 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C01 compound treatment 706564.0 230000.0 0.48 614481.0 138000.0 0.3 0.5474 0.9749 1240212 ChemDiv1_022925 COc1cc(cc(OC)c1OC)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C02 compound treatment 685735.0 210000.0 0.43 668756.0 192000.0 0.42 0.6001 0.9998 1980482 ChemDiv1_022926 CC(=O)C1=NN(C(N1C(C)(C)C)c2ccc3OCOc3c2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C03 compound treatment 713660.0 237000.0 0.49 699127.0 223000.0 0.48 0.6873 1.0 1913245 ChemDiv1_022927 [O-][N+](=O)c1ccccc1N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C04 compound treatment 732489.0 256000.0 0.53 702573.0 226000.0 0.49 0.7201 0.9992 1980483 ChemDiv1_022928 Brc1cnc2c(c1)nc3sc(=Cc4ccccc4)c(=O)n32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C05 compound treatment 746702.0 271000.0 0.56 706393.0 230000.0 0.5 0.7467 0.9983 1401735 ChemDiv1_022929 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(cc5)C(=O)O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C06 compound treatment 689196.0 213000.0 0.44 672179.0 196000.0 0.42 0.6104 0.9998 1980484 ChemDiv1_022930 CC1(C)Cc2c(ccc3ccccc23)/C(=C/C#N)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C07 compound treatment 777967.0 302000.0 0.62 732505.0 256000.0 0.55 0.8323 0.9983 1324870 ChemDiv1_022931 Cc1ccc(N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C08 compound treatment 756186.0 280000.0 0.58 733028.0 257000.0 0.56 0.8013 0.9998 1980485 ChemDiv1_022932 CCOC(=O)C(NC(=O)c1cccc(F)c1)(Nc2sc3CCCCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C09 compound treatment 786988.0 311000.0 0.64 749550.0 273000.0 0.59 0.8716 0.9992 1427541 ChemDiv1_022933 CCN(CC)C(=O)c1cc2C(=O)CCCc2n(c3ccccc3)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C10 compound treatment 739375.0 263000.0 0.54 732388.0 256000.0 0.55 0.7758 1.0 1980486 ChemDiv1_022934 Clc1ccccc1C2NC(=S)NC(=C2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C11 compound treatment 766334.0 290000.0 0.6 725397.0 249000.0 0.54 0.8044 0.9986 1279377 ChemDiv1_022935 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)c5ccccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C12 compound treatment 758433.0 282000.0 0.58 727584.0 251000.0 0.54 0.7963 0.9994 1980487 ChemDiv1_022936 Brc1ccc(cc1)C2=CC(NC(=S)N2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C13 compound treatment 787427.0 311000.0 0.64 735362.0 259000.0 0.56 0.8505 0.9977 1468566 ChemDiv1_022937 O=C(N1c2ccccc2-c3ccccc3S1(=O)=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C14 compound treatment 781901.0 306000.0 0.63 762056.0 286000.0 0.62 0.8833 0.9999 1980488 ChemDiv1_022938 COc1ccc(OC)c(N/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C15 compound treatment 776334.0 300000.0 0.62 773508.0 297000.0 0.64 0.8927 0.9998 1225486 ChemDiv1_022939 Cc1ccc(C)c2-c3ccccc3S(=O)(=O)N(c12)S(=O)(=O)c4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C16 compound treatment 759090.0 283000.0 0.58 733161.0 257000.0 0.56 0.8057 0.9997 1658915 ChemDiv1_022940 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccccc4)c5ccc6OCCOc6c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C17 compound treatment 776134.0 300000.0 0.62 743395.0 267000.0 0.58 0.8463 0.9994 1980489 ChemDiv1_022941 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4c(OC)cc(OC)cc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C18 compound treatment 699999.0 224000.0 0.46 671823.0 195000.0 0.42 0.6256 0.999 1262452 ChemDiv1_022942 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(Br)cc4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C19 compound treatment 709582.0 233000.0 0.48 737904.0 261000.0 0.57 0.7407 0.9968 1698027 ChemDiv1_022943 COc1ccc(c2nc3c([nH]2)c4ccccc4c5ccccc35)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C20 compound treatment 714447.0 238000.0 0.49 721568.0 245000.0 0.53 0.7228 0.9993 1980490 ChemDiv1_022944 CCOC(=O)C1C(NC(=S)NC1(O)C(F)(F)F)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C21 compound treatment 752583.0 276000.0 0.57 743464.0 267000.0 0.58 0.812 1.0 1929011 ChemDiv1_022945 Nc1c(Cl)cc(cc1Cl)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C22 compound treatment 729609.0 253000.0 0.52 712564.0 236000.0 0.51 0.7312 0.9999 1870284 ChemDiv1_022946 [O-][N+](=O)c1ccc(cc1)C2CC(=Nc3ccccc3N2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C23 mock treatment 698905.0 223000.0 0.46 704630.0 228000.0 0.49 0.6742 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 C24 mock treatment 225863.0 -250000.0 -0.52 231392.0 -245000.0 -0.53 -0.7405 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D01 compound treatment 702440.0 226000.0 0.47 611411.0 135000.0 0.29 0.5367 0.9744 1180747 ChemDiv1_022947 CC(CCc1ccccc1)NC(=O)C2(CCOCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D02 compound treatment 654936.0 179000.0 0.37 621070.0 145000.0 0.31 0.4822 0.9966 1716705 ChemDiv1_022948 Cc1ccc(NS(=O)(=O)c2cc(c3cccc4C(=O)Nc2c43)S(=O)(=O)Nc5ccc(C)cc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D03 compound treatment 675676.0 199000.0 0.41 669586.0 193000.0 0.42 0.5867 1.0 1980491 ChemDiv1_022949 COc1ccc(CNCCC2(CCOC(C)(C)C2)c3ccc(F)cc3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D04 compound treatment 709004.0 233000.0 0.48 684290.0 208000.0 0.45 0.6578 0.9995 1980492 ChemDiv1_022950 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D05 compound treatment 721411.0 245000.0 0.51 695775.0 219000.0 0.47 0.6935 0.9995 1980493 ChemDiv1_022951 CC(C)C1(CN2CC3(CN(C1)C2c4ccc(cc4)[N+](=O)[O-])C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D06 compound treatment 666382.0 190000.0 0.39 673066.0 197000.0 0.43 0.5785 0.9992 1980494 ChemDiv1_022952 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D07 compound treatment 732216.0 256000.0 0.53 704342.0 228000.0 0.49 0.7224 0.9994 1127877 ChemDiv1_022953 Cc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)CSC#N)c3ccc(C)cc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D08 compound treatment 738700.0 263000.0 0.54 710220.0 234000.0 0.51 0.7409 0.9994 1980495 ChemDiv1_022954 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D09 compound treatment 769359.0 293000.0 0.61 737696.0 261000.0 0.57 0.8277 0.9994 1732543 ChemDiv1_022955 Cc1ccc(C)c(c1)S(=O)(=O)Nc2ccc3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D10 compound treatment 746829.0 271000.0 0.56 724786.0 248000.0 0.54 0.775 0.9998 1980496 ChemDiv1_022956 CCc1ccc(cc1)S(=O)(=O)N(C(=O)c2ccccc2Cl)c3ccc4oc(C)c(C(=O)C)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D11 compound treatment 774154.0 298000.0 0.62 736592.0 260000.0 0.56 0.833 0.999 1632205 ChemDiv1_022957 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D12 compound treatment 747587.0 271000.0 0.56 695279.0 219000.0 0.47 0.731 0.9965 1723684 ChemDiv1_022958 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(Cl)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D13 compound treatment 767328.0 291000.0 0.6 721255.0 245000.0 0.53 0.7996 0.998 1471990 ChemDiv1_022959 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c4C(=O)CC(C)(C)Cc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D14 compound treatment 768176.0 292000.0 0.6 708781.0 232000.0 0.5 0.7817 0.9959 1454301 ChemDiv1_022960 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D15 compound treatment 760063.0 284000.0 0.59 719523.0 243000.0 0.53 0.7863 0.9985 1230495 ChemDiv1_022961 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D16 compound treatment 766803.0 291000.0 0.6 723727.0 247000.0 0.54 0.8026 0.9984 1721123 ChemDiv1_022962 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D17 compound treatment 758713.0 283000.0 0.58 706492.0 230000.0 0.5 0.7644 0.9969 1477186 ChemDiv1_022963 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCC(C)Cc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D18 compound treatment 764356.0 288000.0 0.59 703100.0 227000.0 0.49 0.7674 0.9954 1553341 ChemDiv1_022964 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3Cl)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D19 compound treatment 753654.0 277000.0 0.57 719314.0 243000.0 0.53 0.7766 0.9991 1650603 ChemDiv1_022965 CC1CCc2c(C1)oc3ccc(NS(=O)(=O)c4ccc5ccccc5c4)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D20 compound treatment 706906.0 231000.0 0.48 697046.0 221000.0 0.48 0.6743 1.0 1550020 ChemDiv1_022966 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccc(cc3)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D21 compound treatment 749724.0 274000.0 0.56 723803.0 247000.0 0.54 0.7778 0.9996 1285846 ChemDiv1_022967 CC1CCc2c(C1)oc3c2cc(NS(=O)(=O)c4ccccc4)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D22 compound treatment 723326.0 247000.0 0.51 702271.0 226000.0 0.49 0.7063 0.9998 1159395 ChemDiv1_022968 CCOC(=O)c1cc2COC(C)(C)Cc2nc1NC(=S)NC(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D23 mock treatment 696202.0 220000.0 0.45 673470.0 197000.0 0.43 0.6226 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 D24 mock treatment 211108.0 -265000.0 -0.55 240115.0 -236000.0 -0.51 -0.7487 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E01 compound treatment 709901.0 234000.0 0.48 629098.0 153000.0 0.33 0.5747 0.9829 1499304 ChemDiv1_022969 CCN1C(=O)C2C(C1=O)C3(C(=O)O)c4ccccc4C2c5ccccc53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E02 compound treatment 726801.0 251000.0 0.52 651131.0 175000.0 0.38 0.6331 0.9881 1980497 ChemDiv1_022970 CC(=O)C1=NN(C(N1C(C)(C)C)c2ccc3OCOc3c2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E03 compound treatment 707694.0 231000.0 0.48 701975.0 225000.0 0.49 0.683 0.9999 1980498 ChemDiv1_022971 [O-][N+](=O)c1ccccc1N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E04 compound treatment 699740.0 224000.0 0.46 687640.0 211000.0 0.46 0.6494 1.0 1120769 ChemDiv1_022972 O=C1C2C(C3c4ccccc4C2c5ccccc35)C(=O)N1c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E05 compound treatment 699390.0 223000.0 0.46 733301.0 257000.0 0.56 0.7188 0.9957 1546500 ChemDiv1_022973 Cc1ccc(cc1Cl)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E06 compound treatment 683137.0 207000.0 0.43 710042.0 234000.0 0.51 0.6595 0.9965 1553507 ChemDiv1_022974 Cn1c(=O)n(C)c2nc(Cl)n(CC(=O)c3ccccc3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E07 compound treatment 735128.0 259000.0 0.53 744720.0 268000.0 0.58 0.7885 0.9991 1364001 ChemDiv1_022975 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E08 compound treatment 767981.0 292000.0 0.6 750938.0 274000.0 0.59 0.8459 1.0 1980499 ChemDiv1_022976 COc1ccc(cc1OC)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E09 compound treatment 750500.0 274000.0 0.57 742783.0 266000.0 0.58 0.8079 1.0 1980500 ChemDiv1_022977 CCOC(=O)CNC(=O)c1cc2C(=O)CCCc2n(c3ccc(C)cc3)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E10 compound treatment 723721.0 248000.0 0.51 728947.0 252000.0 0.55 0.7477 0.9994 1980501 ChemDiv1_022978 CCCC1(CC)NN(C(=S)N1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E11 compound treatment 750266.0 274000.0 0.57 738265.0 262000.0 0.57 0.8007 1.0 1682988 ChemDiv1_022979 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)c5c(C)cccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E12 compound treatment 742565.0 266000.0 0.55 689227.0 213000.0 0.46 0.7144 0.9961 1409377 ChemDiv1_022980 CCC1(CC)NN(C(=S)N1)c2cccc(C)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E13 compound treatment 709156.0 233000.0 0.48 718020.0 242000.0 0.52 0.7097 0.9991 1171699 ChemDiv1_022981 CC(=O)N1c2ccccc2-c3ccccc3S1(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E14 compound treatment 751886.0 276000.0 0.57 717166.0 241000.0 0.52 0.7708 0.999 1484867 ChemDiv1_022982 Cn1c(=O)n(C)c2ncn(Cc3cccc(F)c3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E15 compound treatment 775772.0 300000.0 0.62 786488.0 310000.0 0.67 0.9117 0.9992 1462644 ChemDiv1_022983 COc1ccc2N(C(=O)C)S(=O)(=O)c3ccc(Cl)cc3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E16 compound treatment 759819.0 284000.0 0.59 760489.0 284000.0 0.61 0.8486 0.9997 1727324 ChemDiv1_022984 CC1C(C)C(CCN1C)(OC(=O)C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E17 compound treatment 760866.0 285000.0 0.59 745481.0 269000.0 0.58 0.8272 1.0 1980502 ChemDiv1_022985 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4cc(OC)c(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E18 compound treatment 674967.0 199000.0 0.41 692236.0 216000.0 0.47 0.6203 0.9979 1569844 ChemDiv1_022986 COc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E19 compound treatment 738180.0 262000.0 0.54 728782.0 252000.0 0.55 0.7685 1.0 1162416 ChemDiv1_022987 COc1cccc(c1)c2nc(c([nH]2)c3cccc(OC)c3)c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E20 compound treatment 723331.0 247000.0 0.51 711513.0 235000.0 0.51 0.7204 1.0 1980503 ChemDiv1_022988 CCOC(=O)C1C(NC(=S)NC1(O)C(F)(F)F)c2cccc(Oc3ccccc3)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E21 compound treatment 743166.0 267000.0 0.55 744375.0 268000.0 0.58 0.7997 0.9997 1451483 ChemDiv1_022989 CCOC(=O)c1nc2cc3C(=C(CC)C(C)n3c(C)c2c1C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E22 compound treatment 715311.0 239000.0 0.49 717699.0 241000.0 0.52 0.7182 0.9996 1940681 ChemDiv1_022990 COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E23 mock treatment 702414.0 226000.0 0.47 708442.0 232000.0 0.5 0.6852 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 E24 mock treatment 228544.0 -248000.0 -0.51 222439.0 -254000.0 -0.55 -0.7503 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F01 compound treatment 692490.0 216000.0 0.45 628288.0 152000.0 0.33 0.548 0.9886 1146449 ChemDiv1_022991 O=C(NC1CCCCC1)C2(CCOCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F02 compound treatment 695825.0 220000.0 0.45 659114.0 183000.0 0.4 0.6001 0.9977 1980504 ChemDiv1_022992 O=C1Nc2c(cc(c3cccc1c23)S(=O)(=O)Oc4ccccc4)S(=O)(=O)Oc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F03 compound treatment 666764.0 191000.0 0.39 669591.0 193000.0 0.42 0.5737 0.9995 1980505 ChemDiv1_022993 COc1ccc(cc1)C2(CCNCc3ccc(cc3)N(C)C)CCOC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F04 compound treatment 690725.0 215000.0 0.44 688439.0 212000.0 0.46 0.6375 0.9998 1980506 ChemDiv1_022994 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F05 compound treatment 718682.0 242000.0 0.5 708234.0 232000.0 0.5 0.7086 1.0 1299573 ChemDiv1_022995 CC(C)C1(CN2CC3(CN(C1)C2c4cc(Br)ccc4O)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F06 compound treatment 675965.0 200000.0 0.41 686832.0 210000.0 0.46 0.6135 0.9988 1980507 ChemDiv1_022996 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F07 compound treatment 720878.0 245000.0 0.51 697288.0 221000.0 0.48 0.6951 0.9996 1980508 ChemDiv1_022997 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccccc3)c4c(OCC)cccc24)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F08 compound treatment 699746.0 224000.0 0.46 713159.0 237000.0 0.51 0.6885 0.9986 1980509 ChemDiv1_022998 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(Cl)cc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F09 compound treatment 749847.0 274000.0 0.56 747836.0 271000.0 0.59 0.8147 0.9998 1385259 ChemDiv1_022999 CC1(C)CC(=O)c2c(C1)oc3c(Br)cc(NS(=O)(=O)c4ccccc4)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F10 compound treatment 719019.0 243000.0 0.5 632811.0 156000.0 0.34 0.5937 0.9817 1980510 ChemDiv1_023000 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F11 compound treatment 755594.0 279000.0 0.58 712174.0 236000.0 0.51 0.7685 0.9981 1621850 ChemDiv1_023001 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F12 compound treatment 752865.0 277000.0 0.57 698591.0 222000.0 0.48 0.7438 0.9963 1165060 ChemDiv1_023002 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3Cl)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F13 compound treatment 783544.0 307000.0 0.63 744639.0 268000.0 0.58 0.859 0.999 1412841 ChemDiv1_023003 CC1(C)CC(=O)c2c(C1)oc3c2cc(NS(=O)(=O)c4ccccc4)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F14 compound treatment 743624.0 267000.0 0.55 712432.0 236000.0 0.51 0.7514 0.9992 1247813 ChemDiv1_023004 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F15 compound treatment 751523.0 275000.0 0.57 769407.0 293000.0 0.63 0.8502 0.9985 1173851 ChemDiv1_023005 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F16 compound treatment 731311.0 255000.0 0.53 696247.0 220000.0 0.48 0.7087 0.9987 1864666 ChemDiv1_023006 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F17 compound treatment 762279.0 286000.0 0.59 723429.0 247000.0 0.53 0.7955 0.9988 1668586 ChemDiv1_023007 CC1CCc2oc3ccc(NS(=O)(=O)c4ccc(C)cc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F18 compound treatment 714633.0 238000.0 0.49 732193.0 256000.0 0.55 0.7394 0.9983 1198162 ChemDiv1_023008 CCCC(=O)N(c1ccc2oc(C)c(C(=O)OC)c2c1)S(=O)(=O)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F19 compound treatment 715825.0 240000.0 0.49 679037.0 203000.0 0.44 0.6598 0.9982 1980511 ChemDiv1_023009 [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)Nc2cc3c4CCCCc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F20 compound treatment 715491.0 239000.0 0.49 711398.0 235000.0 0.51 0.7088 0.9999 1553928 ChemDiv1_023010 CNS(=O)(=O)c1cc(c2cccc3C(=O)Nc1c32)S(=O)(=O)NC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F21 compound treatment 763782.0 288000.0 0.59 746829.0 270000.0 0.59 0.8335 1.0 1785350 ChemDiv1_023011 CC(NS(=O)(=O)c1ccc2NC(=O)c3cccc1c23)C4C5CC6CC(C5)CC4C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F22 compound treatment 718249.0 242000.0 0.5 708780.0 232000.0 0.5 0.7088 1.0 1257208 ChemDiv1_023012 CC1(C)Cc2nc3nc(SCC(=O)c4ccccc4)n(c5ccccc5)c(=O)c3cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F23 mock treatment 714431.0 238000.0 0.49 683142.0 207000.0 0.45 0.664 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 F24 mock treatment 232251.0 -244000.0 -0.5 230261.0 -246000.0 -0.53 -0.7329 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G01 compound treatment 675392.0 199000.0 0.41 617584.0 141000.0 0.31 0.5067 0.9893 1980512 ChemDiv1_023013 COc1ccc(OC)c(c1)N2C(=O)C3C(C2=O)C4(C(=O)O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G02 compound treatment 701062.0 225000.0 0.46 662539.0 186000.0 0.4 0.613 0.9975 1930259 ChemDiv1_023014 COc1cc(ccc1O)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G03 compound treatment 697792.0 222000.0 0.46 714664.0 238000.0 0.52 0.688 0.9982 1577923 ChemDiv1_023015 Clc1ccccc1N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G04 compound treatment 698580.0 222000.0 0.46 683253.0 207000.0 0.45 0.641 0.9999 1685571 ChemDiv1_023016 OCCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G05 compound treatment 667028.0 191000.0 0.39 727387.0 251000.0 0.54 0.6625 0.9876 1134049 ChemDiv1_023017 Fc1ccccc1N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G06 compound treatment 669136.0 193000.0 0.4 686871.0 210000.0 0.46 0.6036 0.9978 1980513 ChemDiv1_023018 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3ccccc3F)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G07 compound treatment 721800.0 246000.0 0.51 704980.0 228000.0 0.49 0.7082 0.9999 1393276 ChemDiv1_023019 Cc1cc(I)ccc1N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G08 compound treatment 700223.0 224000.0 0.46 726528.0 250000.0 0.54 0.7097 0.9969 1980514 ChemDiv1_023020 Cn1c2Oc3ccccc3NC(c4cccc(c4)[N+](=O)[O-])c2c(=O)n(C)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G09 compound treatment 665771.0 190000.0 0.39 743630.0 267000.0 0.58 0.6856 0.9819 1278461 ChemDiv1_023021 Cc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)N4CCOCC4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G10 compound treatment 716468.0 240000.0 0.5 725184.0 249000.0 0.54 0.7313 0.9992 1980515 ChemDiv1_023022 CCCC1(CC)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G11 compound treatment 717859.0 242000.0 0.5 740878.0 264000.0 0.57 0.7574 0.9977 1926256 ChemDiv1_023023 COc1ccc(cc1)C2=C(Nc3ccc4oc5ccccc5c4c3)c6ccccc6C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G12 compound treatment 730354.0 254000.0 0.52 694373.0 218000.0 0.47 0.7044 0.9986 1182501 ChemDiv1_023024 CCCC1(CC)NN(C(=S)N1)c2cccc(C)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G13 compound treatment 770649.0 294000.0 0.61 737346.0 261000.0 0.56 0.829 0.9993 1720136 ChemDiv1_023025 Cc1ccc2NS(=O)(=O)c3ccccc3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G14 compound treatment 760794.0 285000.0 0.59 744818.0 268000.0 0.58 0.8261 1.0 1980516 ChemDiv1_023026 CCOc1ccccc1NC(=O)c2cc(ccc2N3CCN(CC)CC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G15 compound treatment 732011.0 256000.0 0.53 759090.0 283000.0 0.61 0.8059 0.9973 1980517 ChemDiv1_023027 COc1ccc2N(S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G16 compound treatment 747171.0 271000.0 0.56 755701.0 279000.0 0.6 0.8228 0.9993 1196357 ChemDiv1_023028 CCC(=O)OC1(CCN(C)CC1C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G17 compound treatment 778113.0 302000.0 0.62 761257.0 285000.0 0.62 0.8765 1.0 1674976 ChemDiv1_023029 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4cccc(OC)c4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G18 compound treatment 714813.0 239000.0 0.49 706586.0 230000.0 0.5 0.7004 1.0 1357521 ChemDiv1_023030 Cc1ccccc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G19 compound treatment 743619.0 267000.0 0.55 737386.0 261000.0 0.56 0.7896 0.9999 1316236 ChemDiv1_023031 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G20 compound treatment 726178.0 250000.0 0.52 723976.0 247000.0 0.54 0.7437 0.9998 1297033 ChemDiv1_023032 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G21 compound treatment 734278.0 258000.0 0.53 748602.0 272000.0 0.59 0.7932 0.9987 1980518 ChemDiv1_023033 [O-][N+](=O)c1ccc(cc1)C2Sc3ccccc3C(=O)N2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G22 compound treatment 708613.0 232000.0 0.48 737723.0 261000.0 0.57 0.7391 0.9967 1980519 ChemDiv1_023034 CC1(C)C2CCC1(C)C(=O)N(C2=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G23 mock treatment 705479.0 229000.0 0.47 717202.0 241000.0 0.52 0.7031 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 G24 mock treatment 230313.0 -246000.0 -0.51 220344.0 -256000.0 -0.55 -0.7509 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H01 compound treatment 663724.0 188000.0 0.39 588592.0 112000.0 0.24 0.4453 0.9747 1980520 ChemDiv1_023035 O=C(CN1CCCC1)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H02 compound treatment 713185.0 237000.0 0.49 628447.0 152000.0 0.33 0.5785 0.9813 1980521 ChemDiv1_023036 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Oc4ccc(OCc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H03 compound treatment 713238.0 237000.0 0.49 679486.0 203000.0 0.44 0.6567 0.9986 1329945 ChemDiv1_023037 COc1ccc(CN(CCC2(CCOC(C)(C)C2)c3ccccc3)C(=O)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H04 compound treatment 702511.0 226000.0 0.47 663469.0 187000.0 0.4 0.6165 0.9974 1980522 ChemDiv1_023038 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H05 compound treatment 696493.0 220000.0 0.45 676799.0 200000.0 0.43 0.6281 0.9997 1214274 ChemDiv1_023039 CC(C)C1(CN2CC3(CN(C1)C2c4ccc(cc4)N(C)C)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H06 compound treatment 708353.0 232000.0 0.48 686159.0 210000.0 0.45 0.6598 0.9996 1980523 ChemDiv1_023040 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(Cl)cc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H07 compound treatment 709202.0 233000.0 0.48 694878.0 218000.0 0.47 0.6743 1.0 1980524 ChemDiv1_023041 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)c4ccccc4C3=O)c5cc(C)c(C)cc25)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H08 compound treatment 700299.0 224000.0 0.46 692043.0 216000.0 0.47 0.657 1.0 1980525 ChemDiv1_023042 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3Cl)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H09 compound treatment 735884.0 260000.0 0.54 718003.0 242000.0 0.52 0.7487 0.9999 1311257 ChemDiv1_023043 CC1(C)CC(=O)c2c(C1)oc3c(Br)cc(NS(=O)(=O)c4ccc5ccccc5c4)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H10 compound treatment 696699.0 221000.0 0.46 701429.0 225000.0 0.49 0.6661 0.9994 1980526 ChemDiv1_023044 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H11 compound treatment 739081.0 263000.0 0.54 708697.0 232000.0 0.5 0.7391 0.9993 1734268 ChemDiv1_023045 Cc1ccc(c(C)c1)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H12 compound treatment 698282.0 222000.0 0.46 666074.0 190000.0 0.41 0.6143 0.9985 1864659 ChemDiv1_023046 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H13 compound treatment 722778.0 247000.0 0.51 700996.0 224000.0 0.49 0.7035 0.9997 1514443 ChemDiv1_023047 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H14 compound treatment 777209.0 301000.0 0.62 726177.0 250000.0 0.54 0.8215 0.9976 1588379 ChemDiv1_023048 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H15 compound treatment 770187.0 294000.0 0.61 719851.0 243000.0 0.53 0.8016 0.9975 1737023 ChemDiv1_023049 Cc1ccccc1S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H16 compound treatment 731478.0 255000.0 0.53 704414.0 228000.0 0.49 0.7214 0.9995 1864667 ChemDiv1_023050 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H17 compound treatment 773781.0 298000.0 0.61 703915.0 227000.0 0.49 0.7824 0.994 1305940 ChemDiv1_023051 CC1CCc2oc3ccc(NS(=O)(=O)c4ccc(Cl)cc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H18 compound treatment 744014.0 268000.0 0.55 730769.0 254000.0 0.55 0.7801 1.0 1374548 ChemDiv1_023052 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H19 compound treatment 750576.0 274000.0 0.57 727596.0 251000.0 0.54 0.7848 0.9998 1345732 ChemDiv1_023053 Cc1ccc(cc1)S(=O)(=O)Nc2cc3c4CCCCc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H20 compound treatment 734049.0 258000.0 0.53 690879.0 214000.0 0.46 0.7045 0.9977 1343413 ChemDiv1_023054 Cc1ccc(C)c(Nc2nc3nonc3n4cnnc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H21 compound treatment 756780.0 281000.0 0.58 1017768.0 541000.0 1.17 1.238 0.9473 1980527 ChemDiv1_023055 CCCCCCCNS(=O)(=O)c1cc(c2cccc3C(=O)Nc1c32)S(=O)(=O)NCCCCCCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H22 compound treatment 700106.0 224000.0 0.46 696438.0 220000.0 0.48 0.6634 0.9999 1496554 ChemDiv1_023056 CC(=C)CSc1nc2nc3CC(C)(C)OCc3cc2c(=O)n1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H23 mock treatment 693395.0 217000.0 0.45 674250.0 198000.0 0.43 0.6197 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 H24 mock treatment 210868.0 -265000.0 -0.55 231685.0 -245000.0 -0.53 -0.762 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I01 compound treatment 670414.0 194000.0 0.4 592244.0 116000.0 0.25 0.4606 0.9744 1657362 ChemDiv1_023057 OC(=O)C1(C2C(C3c4ccccc41)C(=O)N(Cc5ccccc5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I02 compound treatment 683645.0 207000.0 0.43 641262.0 165000.0 0.36 0.555 0.9959 1980528 ChemDiv1_023058 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CC=C)C2c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I03 compound treatment 702705.0 227000.0 0.47 682574.0 206000.0 0.45 0.646 0.9997 1576462 ChemDiv1_023059 OC(=O)c1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I04 compound treatment 664588.0 188000.0 0.39 683277.0 207000.0 0.45 0.5915 0.9976 1980529 ChemDiv1_023060 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C(C)C)c3ccc(C)cc23)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I05 compound treatment 727480.0 251000.0 0.52 708713.0 232000.0 0.5 0.7222 0.9999 1779898 ChemDiv1_023061 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(c5)[N+](=O)[O-])c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I06 compound treatment 649008.0 173000.0 0.36 683321.0 207000.0 0.45 0.5688 0.9937 1980530 ChemDiv1_023062 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3cccc(F)c3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I07 compound treatment 711770.0 236000.0 0.49 724141.0 248000.0 0.54 0.7229 0.9988 1156323 ChemDiv1_023063 Cc1ccc(cc1Cl)N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I08 compound treatment 604562.0 128000.0 0.26 620730.0 144000.0 0.31 0.4081 0.9967 1870732 ChemDiv1_023064 Cn1c2NC3=C(C(c4ccc(cc4)[N+](=O)[O-])c2c(=O)[nH]c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I09 compound treatment 683389.0 207000.0 0.43 726215.0 250000.0 0.54 0.6846 0.9933 1673582 ChemDiv1_023065 COc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)N4CCOCC4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I10 compound treatment 711991.0 236000.0 0.49 721713.0 245000.0 0.53 0.7195 0.9991 1980531 ChemDiv1_023066 CCCC1(CC)NN(C(=S)N1)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I11 compound treatment 725260.0 249000.0 0.51 717602.0 241000.0 0.52 0.7326 1.0 1486368 ChemDiv1_023067 COc1ccc(cc1)c2cc3nc4CCCCCn4c(=O)c3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I12 compound treatment 713259.0 237000.0 0.49 711104.0 235000.0 0.51 0.7051 0.9998 1980532 ChemDiv1_023068 CCC1CCC2(CC1)NN(C(=S)N2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I13 compound treatment 730769.0 255000.0 0.53 722297.0 246000.0 0.53 0.7478 1.0 1980533 ChemDiv1_023069 Cc1ccc(cc1)S(=O)(=O)N2c3ccc(C)cc3-c4ccccc4S2(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I14 compound treatment 752783.0 277000.0 0.57 725560.0 249000.0 0.54 0.7849 0.9996 1367363 ChemDiv1_023070 CCc1c(oc2ccc3c(C)cc(=O)oc3c12)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I15 compound treatment 768000.0 292000.0 0.6 758654.0 282000.0 0.61 0.8578 1.0 1980534 ChemDiv1_023071 COc1ccc2N(S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(Cl)cc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I16 compound treatment 705237.0 229000.0 0.47 677869.0 201000.0 0.44 0.6425 0.9992 1654879 ChemDiv1_023072 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccccc4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I17 compound treatment 742994.0 267000.0 0.55 708509.0 232000.0 0.5 0.7445 0.9989 1242677 ChemDiv1_023073 COc1cc(OC)c(cc1OC)c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I18 compound treatment 688562.0 212000.0 0.44 718479.0 242000.0 0.52 0.6803 0.9961 1608807 ChemDiv1_023074 Cc1ccccc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I19 compound treatment 713412.0 237000.0 0.49 669122.0 193000.0 0.42 0.6411 0.9968 1198269 ChemDiv1_023075 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I20 compound treatment 710225.0 234000.0 0.48 733023.0 257000.0 0.56 0.7342 0.9976 1945636 ChemDiv1_023076 COc1ccc(C2NC(=S)NC(=C2C(=O)Nc3ccccc3)C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I21 compound treatment 713844.0 238000.0 0.49 743229.0 267000.0 0.58 0.7551 0.9967 1980535 ChemDiv1_023077 COc1ccc(cc1)n2nnnc2C3(CCCCC3C)Nc4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I22 compound treatment 724574.0 248000.0 0.51 709556.0 233000.0 0.5 0.7192 1.0 1980536 ChemDiv1_023078 Ic1cccc(c1)C(=O)O/N=C/2\CCCc3c2sc4nc5CCCCCn5c(=O)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I23 mock treatment 720635.0 244000.0 0.5 680200.0 204000.0 0.44 0.6686 0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 I24 mock treatment 210396.0 -266000.0 -0.55 246754.0 -230000.0 -0.5 -0.7396 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J01 compound treatment 685155.0 209000.0 0.43 615889.0 139000.0 0.3 0.5183 0.9847 1512188 ChemDiv1_023079 O=C(Cc1cccc2ccccc12)NCC3(CCOCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J02 compound treatment 681074.0 205000.0 0.42 631842.0 155000.0 0.34 0.5368 0.9935 1980537 ChemDiv1_023080 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Oc4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J03 compound treatment 686940.0 211000.0 0.44 671281.0 195000.0 0.42 0.6057 0.9999 1247683 ChemDiv1_023081 CC(C)C1(CN(CC2(CN(C1)C(=O)C)C(C)C)C(=O)C)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J04 compound treatment 707268.0 231000.0 0.48 678908.0 202000.0 0.44 0.6471 0.9991 1980538 ChemDiv1_023082 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(Cl)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J05 compound treatment 710706.0 235000.0 0.48 701286.0 225000.0 0.49 0.6863 1.0 1532240 ChemDiv1_023083 CC(C)C1(CN2CC3(CN(C1)C2c4ccc(Br)cc4)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J06 compound treatment 705119.0 229000.0 0.47 686837.0 210000.0 0.46 0.6561 0.9998 1980539 ChemDiv1_023084 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J07 compound treatment 712769.0 237000.0 0.49 669768.0 193000.0 0.42 0.6411 0.997 1243511 ChemDiv1_023085 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4-c5c(ssc5=S)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J08 compound treatment 697051.0 221000.0 0.46 681357.0 205000.0 0.44 0.6359 0.9999 1980540 ChemDiv1_023086 CCCC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J09 compound treatment 744387.0 268000.0 0.55 730901.0 254000.0 0.55 0.7808 1.0 1167366 ChemDiv1_023087 Cc1ccc(C)c(c1)S(=O)(=O)Nc2ccc3oc4CC(C)(C)CC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J10 compound treatment 755884.0 280000.0 0.58 728551.0 252000.0 0.55 0.794 0.9996 1980541 ChemDiv1_023088 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc(cc3)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J11 compound treatment 766687.0 290000.0 0.6 718398.0 242000.0 0.52 0.7942 0.9977 1165300 ChemDiv1_023089 Cc1ccccc1S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J12 compound treatment 758611.0 282000.0 0.58 690300.0 214000.0 0.46 0.7395 0.9935 1441285 ChemDiv1_023090 CCCC(=O)N(c1ccc2oc(C)c(C(=O)OCC)c2c1)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J13 compound treatment 717853.0 242000.0 0.5 615599.0 139000.0 0.3 0.5656 0.9708 1980542 ChemDiv1_023091 [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J14 compound treatment 752495.0 276000.0 0.57 718291.0 242000.0 0.52 0.7734 0.9991 1668019 ChemDiv1_023092 CCCC(=O)N(c1ccc2oc(C)c(C(=O)OCC)c2c1)S(=O)(=O)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J15 compound treatment 766657.0 290000.0 0.6 732010.0 256000.0 0.55 0.815 0.9992 1706691 ChemDiv1_023093 CC(C)(C)C1CCc2oc3ccc(NS(=O)(=O)c4ccccc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J16 compound treatment 742994.0 267000.0 0.55 734143.0 258000.0 0.56 0.7838 1.0 1651653 ChemDiv1_023094 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J17 compound treatment 738904.0 263000.0 0.54 709786.0 233000.0 0.5 0.7405 0.9994 1150672 ChemDiv1_023095 CC1CCc2oc3ccc(NS(=O)(=O)c4ccccc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J18 compound treatment 757052.0 281000.0 0.58 678192.0 202000.0 0.44 0.7186 0.9902 1980543 ChemDiv1_023096 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J19 compound treatment 731977.0 256000.0 0.53 709047.0 233000.0 0.5 0.7293 0.9997 1251594 ChemDiv1_023097 Clc1ccc(cc1)S(=O)(=O)Nc2cc3c4CCCCc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J20 compound treatment 727085.0 251000.0 0.52 710220.0 234000.0 0.51 0.7239 0.9999 1980544 ChemDiv1_023098 COc1ccc(Br)cc1C2C(N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)C(=O)N2c5cc(Cl)ccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J21 compound treatment 736963.0 261000.0 0.54 752765.0 276000.0 0.6 0.8035 0.9986 1215467 ChemDiv1_023099 Cc1ccc(NS(=O)(=O)c2cc(c3cccc4C(=O)Nc2c43)S(=O)(=O)Nc5ccc(C)cc5C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J22 compound treatment 746298.0 270000.0 0.56 713159.0 237000.0 0.51 0.7565 0.9991 1184288 ChemDiv1_023100 CC1(C)Cc2nc(NC(=S)Nc3ccccc3)c(cc2CO1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J23 mock treatment 735817.0 260000.0 0.54 705954.0 229000.0 0.5 0.7301 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 J24 mock treatment 221695.0 -255000.0 -0.53 243686.0 -233000.0 -0.5 -0.7278 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K01 compound treatment 655260.0 179000.0 0.37 594093.0 118000.0 0.25 0.4414 0.9834 1980545 ChemDiv1_023101 Cc1cc(ccc1N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K02 compound treatment 677388.0 201000.0 0.42 652752.0 176000.0 0.38 0.5634 0.9991 1406999 ChemDiv1_023102 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CC=C)C2c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K03 compound treatment 674179.0 198000.0 0.41 691879.0 215000.0 0.47 0.6186 0.9978 1121844 ChemDiv1_023103 CC(=O)Oc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K04 compound treatment 658700.0 183000.0 0.38 681868.0 205000.0 0.44 0.5807 0.9966 1945738 ChemDiv1_023104 OC(=O)CCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K05 compound treatment 703792.0 228000.0 0.47 724390.0 248000.0 0.54 0.7116 0.9978 1980546 ChemDiv1_023105 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc6ccccc56)c7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K06 compound treatment 661717.0 186000.0 0.38 690592.0 214000.0 0.46 0.5985 0.9955 1145394 ChemDiv1_023106 CC1CC(C)(C)N(C(=O)Nc2ccc(Cl)c(Cl)c2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K07 compound treatment 682635.0 206000.0 0.43 679711.0 203000.0 0.44 0.6123 0.9999 1980547 ChemDiv1_023107 COc1ccc(cc1)C2=NC(N=C(O2)N3CCCCC3)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K08 compound treatment 719373.0 243000.0 0.5 679400.0 203000.0 0.44 0.6655 0.9978 1507085 ChemDiv1_023108 Cn1c2NC3=C(C(c4cccc(Cl)c4Cl)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K09 compound treatment 711712.0 236000.0 0.49 692500.0 216000.0 0.47 0.6744 0.9998 1980548 ChemDiv1_023109 COC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3N=C1c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K10 compound treatment 676718.0 201000.0 0.41 682847.0 206000.0 0.45 0.6085 0.9993 1980549 ChemDiv1_023110 CCOC(=O)C(=O)N1c2c(C)cccc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K11 compound treatment 724058.0 248000.0 0.51 713032.0 237000.0 0.51 0.7238 1.0 1478352 ChemDiv1_023111 O=S1(=O)Nc2ccccc2-c3ccccc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K12 compound treatment 727244.0 251000.0 0.52 660128.0 184000.0 0.4 0.6475 0.9914 1440265 ChemDiv1_023112 CCC1CCC2(CC1)NN(C(=S)N2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K13 compound treatment 732978.0 257000.0 0.53 735430.0 259000.0 0.56 0.7711 0.9996 1980550 ChemDiv1_023113 Cc1ccc2N(S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K14 compound treatment 698641.0 222000.0 0.46 730548.0 254000.0 0.55 0.7135 0.996 1111769 ChemDiv1_023114 COc1cc(ccc1O)c2nc3ccccc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K15 compound treatment 760159.0 284000.0 0.59 743675.0 267000.0 0.58 0.8234 1.0 1980551 ChemDiv1_023115 COc1ccc2N(S(=O)(=O)c3ccc4ccccc4c3)S(=O)(=O)c5ccc(Cl)cc5-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K16 compound treatment 699365.0 223000.0 0.46 682452.0 206000.0 0.45 0.641 0.9999 1664830 ChemDiv1_023116 COc1ccc(Br)cc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K17 compound treatment 730708.0 255000.0 0.53 726341.0 250000.0 0.54 0.7539 0.9999 1654821 ChemDiv1_023117 COc1ccc(c2nc(c([nH]2)c3ccccc3)c4ccccc4)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K18 compound treatment 705469.0 229000.0 0.47 723352.0 247000.0 0.53 0.7125 0.9982 1496470 ChemDiv1_023118 O=C1CCCC2=C1C(Nc3ccc4ncccc4c23)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K19 compound treatment 806785.0 331000.0 0.68 710146.0 234000.0 0.51 0.8401 0.9891 1686731 ChemDiv1_023119 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4cc(OC)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K20 compound treatment 704105.0 228000.0 0.47 721800.0 245000.0 0.53 0.7081 0.9982 1149842 ChemDiv1_023120 COC(=O)C1C2c3ccccc3O[C@]1(C)N=c4sc(=Cc5ccc(OC)cc5)c(=O)n24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K21 compound treatment 714865.0 239000.0 0.49 739515.0 263000.0 0.57 0.7509 0.9974 1980552 ChemDiv1_023121 COc1ccc(cc1)n2nnnc2C3(CCCCC3)Nc4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K22 compound treatment 734495.0 258000.0 0.53 705686.0 229000.0 0.5 0.7278 0.9993 1623241 ChemDiv1_023122 CCOC(=O)C1Cn2c(S1)nc3-c4ccccc4CC(C)(CC)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K23 mock treatment 706616.0 230000.0 0.48 705216.0 229000.0 0.5 0.6864 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 K24 mock treatment 216815.0 -259000.0 -0.54 244775.0 -232000.0 -0.5 -0.7333 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L01 compound treatment 682124.0 206000.0 0.43 612492.0 136000.0 0.29 0.5087 0.9839 1352621 ChemDiv1_023123 CC(=O)NCC1(CCOCC1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L02 compound treatment 691299.0 215000.0 0.44 639703.0 163000.0 0.35 0.5638 0.9936 1980553 ChemDiv1_023124 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Oc4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L03 compound treatment 688596.0 212000.0 0.44 694463.0 218000.0 0.47 0.6436 0.9993 1933499 ChemDiv1_023125 CC(C)C1(CN2CC3(CN(C1)C2c4cccc(c4)[N+](=O)[O-])C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L04 compound treatment 677283.0 201000.0 0.42 690656.0 214000.0 0.46 0.6213 0.9985 1980554 ChemDiv1_023126 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3Cl)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L05 compound treatment 709750.0 234000.0 0.48 713771.0 237000.0 0.51 0.7041 0.9995 1980555 ChemDiv1_023127 COc1cc(ccc1OC2OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C2OC(=O)C)C(=O)NCCN3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L06 compound treatment 671594.0 195000.0 0.4 690256.0 214000.0 0.46 0.6124 0.9977 1980556 ChemDiv1_023128 CCCC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L07 compound treatment 721400.0 245000.0 0.51 722259.0 246000.0 0.53 0.734 0.9997 1373173 ChemDiv1_023129 COc1ccc2N(C(=O)C(C)N3C(=O)c4ccccc4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L08 compound treatment 653823.0 178000.0 0.37 699933.0 223000.0 0.48 0.6012 0.9907 1980557 ChemDiv1_023130 CCc1ccc(cc1)S(=O)(=O)N(C(=O)C)c2ccc3oc(C)c(C(=O)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L09 compound treatment 697071.0 221000.0 0.46 721013.0 245000.0 0.53 0.6966 0.9972 1300001 ChemDiv1_023131 CCOc1ccc(cc1)S(=O)(=O)Nc2ccc3n(c4CC(C)(C)CC(=O)c4c3c2)S(=O)(=O)c5ccc(OCC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L10 compound treatment 645825.0 170000.0 0.35 668756.0 192000.0 0.42 0.5418 0.9963 1276947 ChemDiv1_023132 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L11 compound treatment 752360.0 276000.0 0.57 723651.0 247000.0 0.53 0.7814 0.9995 1588435 ChemDiv1_023133 Brc1cc(NS(=O)(=O)c2ccc3ccccc3c2)cc4c5C(=O)CCCc5oc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L12 compound treatment 717330.0 241000.0 0.5 712370.0 236000.0 0.51 0.713 0.9999 1864660 ChemDiv1_023134 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L13 compound treatment 725948.0 250000.0 0.52 675062.0 199000.0 0.43 0.6685 0.9959 1288637 ChemDiv1_023135 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L14 compound treatment 735638.0 259000.0 0.54 694833.0 218000.0 0.47 0.7129 0.9981 1276764 ChemDiv1_023136 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L15 compound treatment 752302.0 276000.0 0.57 706068.0 230000.0 0.5 0.7544 0.9977 1147911 ChemDiv1_023137 CC(C)(C)C1CCc2oc3ccc(NS(=O)(=O)c4ccc(F)cc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L16 compound treatment 728738.0 253000.0 0.52 702967.0 226000.0 0.49 0.7152 0.9995 1584730 ChemDiv1_023138 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccc(CC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L17 compound treatment 760262.0 284000.0 0.59 713977.0 237000.0 0.51 0.7781 0.9978 1381673 ChemDiv1_023139 CC1CCc2c(C1)oc3ccc(NS(=O)(=O)c4ccc(cc4)C(C)(C)C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L18 compound treatment 697354.0 221000.0 0.46 675880.0 199000.0 0.43 0.628 0.9996 1980558 ChemDiv1_023140 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L19 compound treatment 723629.0 247000.0 0.51 727343.0 251000.0 0.54 0.7451 0.9995 1585783 ChemDiv1_023141 O=S(=O)(Nc1cc2c3CCCCc3oc2c4ccccc14)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L20 compound treatment 744111.0 268000.0 0.55 687370.0 211000.0 0.46 0.7138 0.9954 1310031 ChemDiv1_023142 COc1cccc(c1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L21 compound treatment 738113.0 262000.0 0.54 741043.0 265000.0 0.57 0.7872 0.9996 1642667 ChemDiv1_023143 COC(=O)c1ccccc1NS(=O)(=O)c2cc(c3cccc4C(=O)Nc2c43)S(=O)(=O)Nc5ccccc5C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L22 compound treatment 750669.0 274000.0 0.57 707834.0 231000.0 0.5 0.7547 0.9981 1339713 ChemDiv1_023144 CCOC(=O)c1c(NC(=S)Nc2ccc(C)cc2)sc3COC(C)(C)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L23 mock treatment 744685.0 268000.0 0.55 727085.0 251000.0 0.54 0.7754 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 L24 mock treatment 212585.0 -264000.0 -0.54 214093.0 -262000.0 -0.57 -0.7864 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M01 compound treatment 658071.0 182000.0 0.38 619070.0 143000.0 0.31 0.4837 0.9953 1980559 ChemDiv1_023145 Cc1ccc(cc1[N+](=O)[O-])N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M02 compound treatment 652616.0 176000.0 0.36 644354.0 168000.0 0.36 0.5144 1.0 1980560 ChemDiv1_023146 COc1ccc(cc1)C2=CC(NC(=S)N2)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M03 compound treatment 689137.0 213000.0 0.44 705149.0 229000.0 0.49 0.6608 0.9983 1522283 ChemDiv1_023147 Cc1ccc(N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M04 compound treatment 638834.0 163000.0 0.34 648345.0 172000.0 0.37 0.5004 0.9987 1549787 ChemDiv1_023148 CCc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M05 compound treatment 672212.0 196000.0 0.4 695505.0 219000.0 0.47 0.6213 0.9969 1317223 ChemDiv1_023149 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5Cl)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M06 compound treatment 667668.0 191000.0 0.4 681098.0 205000.0 0.44 0.5926 0.9984 1458777 ChemDiv1_023150 COc1cc(cc(OC)c1OC)C(=O)N2c3ccccc3-c4c(ssc4=S)C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M07 compound treatment 711361.0 235000.0 0.49 707036.0 231000.0 0.5 0.6961 0.9999 1656044 ChemDiv1_023151 CC1(C)CC(=O)c2cc(C(=O)N3CCOCC3)c(=O)n(c4ccccc4)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M08 compound treatment 660815.0 185000.0 0.38 668237.0 192000.0 0.42 0.5629 0.9991 1931451 ChemDiv1_023152 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3cccc(c3)[N+](=O)[O-])c4ccc(OC)cc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M09 compound treatment 653097.0 177000.0 0.37 682823.0 206000.0 0.45 0.574 0.995 1980561 ChemDiv1_023153 COC(=O)CN1C(c2ccccc2)c3cc(Cl)ccc3N=C1c4cc(OC)c(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M10 compound treatment 689511.0 213000.0 0.44 671978.0 195000.0 0.42 0.6105 0.9998 1980562 ChemDiv1_023154 CCCCC1(C)NN(C(=S)N1)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M11 compound treatment 725691.0 249000.0 0.52 702644.0 226000.0 0.49 0.7103 0.9997 1980563 ChemDiv1_023155 [O-][N+](=O)c1ccc2NS(=O)(=O)c3ccccc3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M12 compound treatment 667382.0 191000.0 0.39 684498.0 208000.0 0.45 0.5974 0.9978 1926144 ChemDiv1_023156 COc1cc(NC(=O)c2cc(ccc2N3CCCCCC3)[N+](=O)[O-])c4ncccc4c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M13 compound treatment 704223.0 228000.0 0.47 689068.0 213000.0 0.46 0.6582 0.9999 1191718 ChemDiv1_023157 Cc1ccc2N(S(=O)(=O)c3ccc4ccccc4c3)S(=O)(=O)c5ccccc5-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M14 compound treatment 702762.0 227000.0 0.47 703207.0 227000.0 0.49 0.6777 0.9997 1206018 ChemDiv1_023158 CC1(C)Oc2ccc(NC(=O)Cc3ccc(F)cc3)cc2O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M15 compound treatment 721940.0 246000.0 0.51 732678.0 256000.0 0.55 0.7508 0.999 1307217 ChemDiv1_023159 Clc1cccc-2c1NS(=O)(=O)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M16 compound treatment 700151.0 224000.0 0.46 693370.0 217000.0 0.47 0.6588 1.0 1199499 ChemDiv1_023160 COc1ccc(Br)cc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M17 compound treatment 702547.0 226000.0 0.47 711838.0 235000.0 0.51 0.6906 0.9991 1729290 ChemDiv1_023161 COc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M18 compound treatment 724449.0 248000.0 0.51 699715.0 223000.0 0.48 0.704 0.9996 1639097 ChemDiv1_023162 Cc1ccsc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M19 compound treatment 735851.0 260000.0 0.54 682905.0 206000.0 0.45 0.6949 0.9959 1980564 ChemDiv1_023163 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4ccc(OC)c(OC)c4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M20 compound treatment 689620.0 213000.0 0.44 719465.0 243000.0 0.53 0.6834 0.9961 1507835 ChemDiv1_023164 COC(=O)C1C2c3ccccc3O[C@]1(C)N=c4sc(=Cc5ccc(cc5)C(C)C)c(=O)n24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M21 compound treatment 715894.0 240000.0 0.49 714866.0 238000.0 0.52 0.7147 0.9998 1980565 ChemDiv1_023165 COc1ccc(cc1)n2nnnc2C3(CCCCC3)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M22 compound treatment 695178.0 219000.0 0.45 702685.0 226000.0 0.49 0.6658 0.9992 1244967 ChemDiv1_023166 CCOC(=O)C1Cn2c(S1)nc3-c4ccccc4CC(C)(C)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M23 mock treatment 717885.0 242000.0 0.5 692004.0 216000.0 0.47 0.6826 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 M24 mock treatment 201087.0 -275000.0 -0.57 391745.0 -84800.0 -0.18 -0.5313 -0.8902 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N01 compound treatment 681117.0 205000.0 0.42 624421.0 148000.0 0.32 0.5255 0.9906 1113690 ChemDiv1_023167 CC(=O)N1CCCc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N02 compound treatment 656388.0 180000.0 0.37 631862.0 155000.0 0.34 0.5008 0.9987 1980566 ChemDiv1_023168 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)Oc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N03 compound treatment 729261.0 253000.0 0.52 678675.0 202000.0 0.44 0.6788 0.9961 1666760 ChemDiv1_023169 CC(C)C1(CN2CC3(CN(C1)C2c4cccc(Br)c4)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N04 compound treatment 634775.0 159000.0 0.33 677169.0 201000.0 0.43 0.5386 0.9903 1980567 ChemDiv1_023170 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N05 compound treatment 664813.0 189000.0 0.39 660169.0 184000.0 0.4 0.5564 0.9999 1412919 ChemDiv1_023171 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccc(OC(=O)c5ccccc5F)c4)C(=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N06 compound treatment 660061.0 184000.0 0.38 649436.0 173000.0 0.37 0.5331 1.0 1980568 ChemDiv1_023172 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N07 compound treatment 700228.0 224000.0 0.46 707871.0 231000.0 0.5 0.6811 0.9992 1120529 ChemDiv1_023173 Cc1cccc(N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N08 compound treatment 683190.0 207000.0 0.43 678842.0 202000.0 0.44 0.6118 0.9999 1980569 ChemDiv1_023174 CCc1ccc(cc1)S(=O)(=O)N(C(=O)c2ccccc2)c3ccc4oc(C)c(C(=O)C)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N09 compound treatment 701684.0 225000.0 0.47 720045.0 244000.0 0.53 0.7019 0.9981 1980570 ChemDiv1_023175 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3n(c(C)c(C(=O)C)c3c2)S(=O)(=O)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N10 compound treatment 709051.0 233000.0 0.48 683147.0 207000.0 0.45 0.6562 0.9994 1205499 ChemDiv1_023176 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N11 compound treatment 724226.0 248000.0 0.51 732795.0 256000.0 0.55 0.7543 0.9992 1132987 ChemDiv1_023177 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2ccc3oc4CC(C)(C)CC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N12 compound treatment 682191.0 206000.0 0.43 672878.0 196000.0 0.43 0.6012 1.0 1864661 ChemDiv1_023178 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N13 compound treatment 718752.0 243000.0 0.5 678521.0 202000.0 0.44 0.6632 0.9977 1492963 ChemDiv1_023179 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N14 compound treatment 687586.0 211000.0 0.44 688789.0 212000.0 0.46 0.6335 0.9997 1132129 ChemDiv1_023180 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N15 compound treatment 756667.0 280000.0 0.58 717448.0 241000.0 0.52 0.7782 0.9986 1253260 ChemDiv1_023181 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCC(C)Cc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N16 compound treatment 687243.0 211000.0 0.44 690162.0 214000.0 0.46 0.6351 0.9996 1157655 ChemDiv1_023182 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N17 compound treatment 724221.0 248000.0 0.51 662303.0 186000.0 0.4 0.6464 0.9929 1980571 ChemDiv1_023183 CC1CCc2c(C1)oc3ccc(NS(=O)(=O)c4cccc(c4)[N+](=O)[O-])cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N18 compound treatment 728765.0 253000.0 0.52 689901.0 213000.0 0.46 0.6953 0.9982 1980572 ChemDiv1_023184 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N19 compound treatment 660594.0 184000.0 0.38 727124.0 251000.0 0.54 0.6527 0.985 1619530 ChemDiv1_023185 O=S(=O)(Nc1cc2c3CCCCc3oc2c4ccccc14)c5ccc6ccccc6c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N20 compound treatment 3236098.0 2760000.0 5.7 3611904.0 3140000.0 6.79 8.8272 0.9962 1485806 ChemDiv1_023186 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3CN(Cc4ccccc4)CCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N21 compound treatment 736227.0 260000.0 0.54 733156.0 257000.0 0.56 0.7724 0.9999 1534249 ChemDiv1_023187 Cc1ccc(C)c(NS(=O)(=O)c2cc(c3cccc4C(=O)Nc2c43)S(=O)(=O)Nc5cc(C)ccc5C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N22 compound treatment 699867.0 224000.0 0.46 709781.0 233000.0 0.5 0.6835 0.999 1980573 ChemDiv1_023188 CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc3COC(C)(CC)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N23 mock treatment 709202.0 233000.0 0.48 684252.0 208000.0 0.45 0.6581 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 N24 mock treatment 369911.0 -106000.0 -0.22 371136.0 -105000.0 -0.23 -0.3164 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O01 compound treatment 653579.0 177000.0 0.37 620112.0 144000.0 0.31 0.4787 0.9967 1980574 ChemDiv1_023189 Cc1cc(ccc1N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O02 compound treatment 678551.0 202000.0 0.42 611957.0 135000.0 0.29 0.5027 0.985 1298880 ChemDiv1_023190 Cc1ccccc1Cn2c(=O)n(C)c3ncn(C)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O03 compound treatment 691275.0 215000.0 0.44 645181.0 169000.0 0.37 0.5721 0.9953 1980575 ChemDiv1_023191 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5[N+](=O)[O-])c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O04 compound treatment 666483.0 190000.0 0.39 651338.0 175000.0 0.38 0.5453 0.9998 1980576 ChemDiv1_023192 Cc1ccc(NC2=CC(N(C2=O)c3ccc(C)cc3)c4cccc(c4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O05 compound treatment 673911.0 198000.0 0.41 674071.0 198000.0 0.43 0.591 0.9997 1587947 ChemDiv1_023193 Cc1ccc(N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O06 compound treatment 638695.0 162000.0 0.34 635666.0 159000.0 0.34 0.4808 0.9999 1980577 ChemDiv1_023194 CC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O07 compound treatment 703156.0 227000.0 0.47 671193.0 195000.0 0.42 0.6293 0.9986 1272651 ChemDiv1_023195 CC1(C)CC(=O)c2cc(C(=O)NCC=C)c(=O)n(c3ccccc3)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O08 compound treatment 620719.0 145000.0 0.3 662257.0 186000.0 0.4 0.4953 0.9892 1293971 ChemDiv1_023196 Cc1ccccc1Nc2coc3ccc4c(C)cc(=O)oc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O09 compound treatment 669312.0 193000.0 0.4 662294.0 186000.0 0.4 0.5662 1.0 1980578 ChemDiv1_023197 NCCC(=O)N1c2ccccc2Sc3ccc(cc13)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O10 compound treatment 660322.0 184000.0 0.38 651760.0 175000.0 0.38 0.537 1.0 1980579 ChemDiv1_023198 CC(=O)Nc1cc2c(C)cc(=O)oc2c3C(=O)/C(=C/c4ccc(Cl)cc4)/Oc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O11 compound treatment 706016.0 230000.0 0.47 665945.0 189000.0 0.41 0.6254 0.9974 1980580 ChemDiv1_023199 O=S(=O)(N1c2ccccc2-c3ccccc3S1(=O)=O)c4ccc5ccccc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O12 compound treatment 664203.0 188000.0 0.39 637454.0 161000.0 0.35 0.5208 0.9985 1980581 ChemDiv1_023200 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O13 compound treatment 674976.0 199000.0 0.41 670530.0 194000.0 0.42 0.5871 0.9999 1240548 ChemDiv1_023201 CC(=O)N1c2c(C)ccc(C)c2-c3ccccc3S1(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O14 compound treatment 673413.0 197000.0 0.41 641864.0 165000.0 0.36 0.541 0.9979 1162382 ChemDiv1_023202 CN1C2NC(=O)N(C2N(C)C1=O)C3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O15 compound treatment 686173.0 210000.0 0.43 712969.0 236000.0 0.51 0.6684 0.9966 1980582 ChemDiv1_023203 [O-][N+](=O)c1cc(Cl)c2NS(=O)(=O)c3ccccc3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O16 compound treatment 664327.0 188000.0 0.39 622504.0 146000.0 0.32 0.4981 0.9948 1198791 ChemDiv1_023204 CN(C)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O17 compound treatment 716894.0 241000.0 0.5 673173.0 197000.0 0.43 0.6523 0.997 1577581 ChemDiv1_023205 COc1ccccc1c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O18 compound treatment 668714.0 193000.0 0.4 658394.0 182000.0 0.39 0.5594 1.0 1980583 ChemDiv1_023206 COc1cc2c(cc1NC(=O)Cc3ccc(cc3)[N+](=O)[O-])oc4ccccc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O19 compound treatment 706870.0 231000.0 0.48 706626.0 230000.0 0.5 0.6889 0.9997 1980584 ChemDiv1_023207 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4cc(OC)c(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O20 compound treatment 701113.0 225000.0 0.46 687081.0 211000.0 0.46 0.6506 1.0 1980585 ChemDiv1_023208 C[C@@]1(Oc2ccccc2C3C1C(=O)Nc4ccccc4)N=c5sc(=Cc6ccc(cc6)[N+](=O)[O-])c(=O)n35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O21 compound treatment 709619.0 233000.0 0.48 681031.0 205000.0 0.44 0.6538 0.9991 1980586 ChemDiv1_023209 CCOC(=O)c1ccc(cc1)n2nnnc2C3(CCCCC3)Nc4ccc(NC(=O)C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O22 compound treatment 688597.0 212000.0 0.44 668723.0 192000.0 0.42 0.6042 0.9997 1980587 ChemDiv1_023210 CC(=O)C1Cn2c(S1)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O23 mock treatment 689659.0 213000.0 0.44 684936.0 208000.0 0.45 0.6306 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 O24 mock treatment 383022.0 -93200.0 -0.19 294274.0 -182000.0 -0.39 -0.4149 -0.9455 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P01 compound treatment 644470.0 168000.0 0.35 604077.0 128000.0 0.28 0.4409 0.9935 1153511 ChemDiv1_023211 COc1ccc(CC(=O)N2CCCc3ccccc23)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P02 compound treatment 671562.0 195000.0 0.4 598908.0 122000.0 0.26 0.4725 0.9792 1650755 ChemDiv1_023212 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P03 compound treatment 673089.0 197000.0 0.41 619706.0 143000.0 0.31 0.5066 0.9911 1784501 ChemDiv1_023213 CC1(CN2CC3(C)CN(C1)C2c4ccccc4[N+](=O)[O-])C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P04 compound treatment 680358.0 204000.0 0.42 618268.0 142000.0 0.31 0.515 0.9878 1980588 ChemDiv1_023214 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P05 compound treatment 664272.0 188000.0 0.39 626513.0 150000.0 0.32 0.5041 0.9961 1980589 ChemDiv1_023215 CCCOc1ccccc1N=c2ssc3c2-c4cc(OC)ccc4NC3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P06 compound treatment 658794.0 183000.0 0.38 629200.0 153000.0 0.33 0.5002 0.9979 1980590 ChemDiv1_023216 CC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P07 compound treatment 689250.0 213000.0 0.44 637678.0 161000.0 0.35 0.5577 0.9934 1637027 ChemDiv1_023217 CC1CC(C)(C)N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P08 compound treatment 680219.0 204000.0 0.42 628746.0 152000.0 0.33 0.5308 0.9926 1980591 ChemDiv1_023218 CCc1ccc(cc1)S(=O)(=O)N(C(=O)c2ccncc2)c3ccc4oc(C)c(C(=O)C)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P09 compound treatment 686197.0 210000.0 0.43 646620.0 170000.0 0.37 0.5669 0.9967 1424937 ChemDiv1_023219 CCOC(=O)c1c(C)n(c2ccc(NS(=O)(=O)c3ccc(CC)cc3)cc12)S(=O)(=O)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P10 compound treatment 676785.0 201000.0 0.41 635749.0 159000.0 0.34 0.5365 0.9958 1538740 ChemDiv1_023220 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P11 compound treatment 705593.0 229000.0 0.47 646447.0 170000.0 0.37 0.5949 0.9922 1245181 ChemDiv1_023221 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CC(C)(C)CC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P12 compound treatment 690093.0 214000.0 0.44 635122.0 159000.0 0.34 0.555 0.9923 1269252 ChemDiv1_023222 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3Cl)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P13 compound treatment 703228.0 227000.0 0.47 613236.0 137000.0 0.3 0.5407 0.9754 1980592 ChemDiv1_023223 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2cc(Cl)c3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P14 compound treatment 674858.0 199000.0 0.41 657663.0 181000.0 0.39 0.5673 0.9997 1864664 ChemDiv1_023224 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(cc3)[N+](=O)[O-])S(=O)(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P15 compound treatment 674194.0 198000.0 0.41 644987.0 168000.0 0.36 0.5469 0.9984 1699770 ChemDiv1_023225 CC1CCc2oc3ccc(NS(=O)(=O)c4ccc(cc4)C(C)(C)C)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P16 compound treatment 708073.0 232000.0 0.48 676301.0 200000.0 0.43 0.6443 0.9987 1864674 ChemDiv1_023226 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P17 compound treatment 690898.0 215000.0 0.44 646547.0 170000.0 0.37 0.5737 0.9957 1383002 ChemDiv1_023227 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CC(C)CCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P18 compound treatment 692431.0 216000.0 0.45 652673.0 176000.0 0.38 0.5853 0.9969 1980593 ChemDiv1_023228 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccc(C)cc3)S(=O)(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P19 compound treatment 680214.0 204000.0 0.42 662303.0 186000.0 0.4 0.5822 0.9997 1517229 ChemDiv1_023229 CC1CCc2c(C1)oc3c2cc(NS(=O)(=O)c4ccc(C)cc4)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P20 compound treatment 703833.0 228000.0 0.47 656419.0 180000.0 0.39 0.6076 0.9956 1226753 ChemDiv1_023230 CCOC(=O)c1c(NC(=S)NCCc2ccccc2)sc3COC(C)(C)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P21 compound treatment 684571.0 208000.0 0.43 650499.0 174000.0 0.38 0.5705 0.9978 1598194 ChemDiv1_023231 COc1ccc(NS(=O)(=O)c2cc(c3NC(=O)c4cccc2c34)S(=O)(=O)c5ccc(OC)cc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P22 compound treatment 726976.0 251000.0 0.52 621870.0 145000.0 0.31 0.5885 0.9715 1190417 ChemDiv1_023232 CCOC(=O)c1c(NC(=S)NC2CCCCC2)sc3COC(C)(CC)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P23 mock treatment 651553.0 175000.0 0.36 618657.0 142000.0 0.31 0.4735 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.652 P24 mock treatment 423893.0 -52300.0 -0.11 468115.0 -8380.0 -0.02 -0.0892 -0.8145 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A01 compound treatment 665247.0 205000.0 0.42 628549.0 153000.0 0.33 0.5338 0.9926 1730327 ChemDiv1_023233 CCC1(CN2CC3(CC)CN(C1)C2c4ccccc4)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A02 compound treatment 675586.0 216000.0 0.44 625933.0 150000.0 0.33 0.5449 0.9882 1980594 ChemDiv1_023234 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccccc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A03 compound treatment 767150.0 307000.0 0.63 719126.0 244000.0 0.53 0.8211 0.9958 1980595 ChemDiv1_023235 CC1(C)CC2(CCO1)N3CC4(CN2CC(C3)([N+](=O)[O-])C4(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A04 compound treatment 689206.0 229000.0 0.47 639983.0 164000.0 0.36 0.5862 0.9902 1980596 ChemDiv1_023236 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(OC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A05 compound treatment 751107.0 291000.0 0.6 685101.0 210000.0 0.45 0.7456 0.9904 1474571 ChemDiv1_023237 Cc1c(C#N)c2nc3CCCc3c(c4ccc(Br)cc4)c2n1c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A06 compound treatment 774148.0 314000.0 0.65 701776.0 226000.0 0.49 0.8048 0.9904 1586210 ChemDiv1_023238 CCCCC(=O)N1C2=C(C(c3ccc(Cl)cc3)c4c1n(C)c(=O)n(C)c4=O)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A07 compound treatment 760884.0 301000.0 0.62 679960.0 204000.0 0.44 0.752 0.9862 1391604 ChemDiv1_023239 Brc1ccc(cc1)C(=O)Cn2cnc3c(C#N)c4CCCCn4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A08 compound treatment 720243.0 260000.0 0.54 669410.0 194000.0 0.42 0.6766 0.9926 1870708 ChemDiv1_023240 CC1(C)N(C(=O)CN2C(=O)c3cccc([N+](=O)[O-])c3C2=O)c4ccccc4-c5c1ssc5=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A09 compound treatment 767109.0 307000.0 0.63 662153.0 187000.0 0.4 0.7339 0.9763 1980597 ChemDiv1_023241 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A10 compound treatment 788860.0 329000.0 0.68 877581.0 402000.0 0.87 1.0953 0.9924 1526786 ChemDiv1_023242 CC1(C)CC(=O)C=C(C1)NCCc2ccc(cc2)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A11 compound treatment 714061.0 254000.0 0.52 663359.0 188000.0 0.41 0.6583 0.9921 1367826 ChemDiv1_023243 CCOc1cc(cc(Br)c1OC)C2CC(=O)Nc3c2ccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A12 compound treatment 751248.0 291000.0 0.6 652077.0 177000.0 0.38 0.6953 0.9761 1980598 ChemDiv1_023244 COc1cc2CC3(CCCC3)N/C(=N\c4ccc(Br)cc4)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A13 compound treatment 672615.0 213000.0 0.44 617576.0 142000.0 0.31 0.5277 0.9849 1923708 ChemDiv1_023245 COc1cccc(c1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A14 compound treatment 737915.0 278000.0 0.57 671590.0 196000.0 0.42 0.7057 0.989 1156319 ChemDiv1_023246 Clc1ccc(NC(=O)N2CCCc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A15 compound treatment 755075.0 295000.0 0.61 680853.0 205000.0 0.44 0.7449 0.988 1980599 ChemDiv1_023247 CCOC(=O)C1=CSC2(S1)C=C(SC3=C2c4cc(OCC)ccc4N(C(=O)Cc5ccccc5)C3(C)C)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A16 compound treatment 1011951.0 552000.0 1.14 876824.0 401000.0 0.87 1.4198 0.991 1928832 ChemDiv1_023248 COc1ccc(C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A17 compound treatment 720002.0 260000.0 0.54 730156.0 255000.0 0.55 0.7692 0.9999 1346840 ChemDiv1_023249 Cc1cc(O)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A18 compound treatment 722567.0 263000.0 0.54 637720.0 162000.0 0.35 0.6315 0.9779 1980600 ChemDiv1_023250 COc1cccc(c1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A19 compound treatment 779262.0 319000.0 0.66 703151.0 228000.0 0.49 0.8144 0.9897 1945899 ChemDiv1_023251 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(OCC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A20 compound treatment 697328.0 237000.0 0.49 614252.0 139000.0 0.3 0.5587 0.9724 1536893 ChemDiv1_023252 COCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cc(OC)ccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A21 compound treatment 713935.0 254000.0 0.52 681381.0 206000.0 0.45 0.6857 0.9967 1980601 ChemDiv1_023253 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(cc3)N(CC)CC)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A22 compound treatment 666847.0 207000.0 0.43 567642.0 92100.0 0.2 0.4429 0.9399 1930518 ChemDiv1_023254 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4cccc(c4)[N+](=O)[O-])c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A23 mock treatment 596940.0 137000.0 0.28 610362.0 135000.0 0.29 0.4062 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 A24 mock treatment 251560.0 -208000.0 -0.43 245592.0 -230000.0 -0.5 -0.6562 -0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B01 compound treatment 646382.0 186000.0 0.38 594286.0 119000.0 0.26 0.4538 0.9808 1319803 ChemDiv1_023255 COc1ccc(cc1)C2N(CCN(C)C)C(=O)C(=C2C(=O)c3ccccc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B02 compound treatment 817210.0 357000.0 0.74 832170.0 357000.0 0.77 1.0672 0.9997 1576318 ChemDiv1_023256 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4ccccc4CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B03 compound treatment 759011.0 299000.0 0.62 743716.0 268000.0 0.58 0.8469 0.9995 1548417 ChemDiv1_023257 CCOC(=O)c1nnn(c1CN2CCN(CC2)c3ccccc3)c4nonc4N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B04 compound treatment 683500.0 223000.0 0.46 669242.0 194000.0 0.42 0.6227 0.9989 1545816 ChemDiv1_023258 CCOC(=O)c1cc(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2Br)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B05 compound treatment 702828.0 243000.0 0.5 672338.0 197000.0 0.43 0.6556 0.9967 1980602 ChemDiv1_023259 CC1CC2(CCCCC2)N(C(=O)C)c3c(C)c(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B06 compound treatment 680100.0 220000.0 0.45 647250.0 172000.0 0.37 0.5841 0.995 1980603 ChemDiv1_023260 c1csc(c1)c2nc3cc4ccccc4cc3nc2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B07 compound treatment 1174863.0 715000.0 1.48 1297482.0 822000.0 1.78 2.3014 0.9957 1980604 ChemDiv1_023261 CCOC(=O)C1=C(Nc2ccc(C)cc2)S/C(=C\c3ccc(O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B08 compound treatment 696558.0 237000.0 0.49 705474.0 230000.0 0.5 0.6972 1.0 1380548 ChemDiv1_023262 CSCCC(N1C2NC(=O)NC2NC1=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B09 compound treatment 754271.0 294000.0 0.61 734457.0 259000.0 0.56 0.8258 0.9992 1528306 ChemDiv1_023263 CCCN1C2C(NC1=O)NC(=O)N2CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B10 compound treatment 740242.0 280000.0 0.58 707025.0 232000.0 0.5 0.7633 0.9974 1980605 ChemDiv1_023264 CC(=C)CSc1nnc2n(c3ccc(C)cc3)c(=O)c4c5CCCCCc5sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B11 compound treatment 732333.0 272000.0 0.56 697858.0 222000.0 0.48 0.7378 0.997 1980606 ChemDiv1_023265 [O-][N+](=O)c1ccc(Cl)c(c1)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B12 compound treatment 730149.0 270000.0 0.56 697812.0 222000.0 0.48 0.7345 0.9973 1980607 ChemDiv1_023266 CCCCCNc1ncnc2c1sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B13 compound treatment 750857.0 291000.0 0.6 731633.0 256000.0 0.55 0.8165 0.9992 1587369 ChemDiv1_023267 C(N1CCn2c3C1CCCc3c4ccccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B14 compound treatment 732633.0 273000.0 0.56 696815.0 221000.0 0.48 0.7366 0.9968 1941075 ChemDiv1_023268 CCC1(C)CC(CCNCc2ccc(OC)cc2)(CCO1)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B15 compound treatment 776471.0 316000.0 0.65 742892.0 267000.0 0.58 0.8711 0.9982 1980608 ChemDiv1_023269 Fc1ccc(cc1)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B16 compound treatment 746968.0 287000.0 0.59 754714.0 279000.0 0.6 0.8461 0.9999 1133307 ChemDiv1_023270 CC(=C)CSc1nnc2n(c3ccccc3C)c(=O)c4c5CCCCc5sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B17 compound treatment 833910.0 374000.0 0.77 769690.0 294000.0 0.64 0.996 0.9954 1866868 ChemDiv1_023271 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B18 compound treatment 672536.0 212000.0 0.44 683335.0 208000.0 0.45 0.6282 0.9999 1565267 ChemDiv1_023272 CC1C=C(C)C2C(C)C1COC2c3ccccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B19 compound treatment 797281.0 337000.0 0.7 754360.0 279000.0 0.6 0.919 0.9975 1181225 ChemDiv1_023273 Cc1ccc(N2COc3ccc4c(C)cc(=O)oc4c3C2)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B20 compound treatment 754006.0 294000.0 0.61 726019.0 251000.0 0.54 0.8125 0.9984 1453745 ChemDiv1_023274 CC1C=C(C)C2C(C)C1(CO)COC2c3ccccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B21 compound treatment 740078.0 280000.0 0.58 661305.0 186000.0 0.4 0.6931 0.9843 1313732 ChemDiv1_023275 CCOC(=O)c1cnc2ccccc2c1Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B22 compound treatment 694408.0 234000.0 0.48 706605.0 231000.0 0.5 0.6958 0.9999 1980609 ChemDiv1_023276 C/C=C/N1C(=S)NC2(O)c3ccccc3C(=O)C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B23 mock treatment 689911.0 230000.0 0.47 618102.0 143000.0 0.31 0.5538 0.9783 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 B24 mock treatment 254105.0 -206000.0 -0.43 230617.0 -245000.0 -0.53 -0.6754 -0.994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C01 compound treatment 653893.0 194000.0 0.4 632400.0 157000.0 0.34 0.5231 0.9967 1730217 ChemDiv1_023277 CC(=O)N1N=C2CC(C)(C)OCC2C1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C02 compound treatment 698070.0 238000.0 0.49 703987.0 228000.0 0.49 0.6971 1.0 1980610 ChemDiv1_023278 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(OC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C03 compound treatment 713976.0 254000.0 0.52 701551.0 226000.0 0.49 0.7166 0.9994 1735517 ChemDiv1_023279 Brc1ccc2n3CCN(Cc4ccccc4)C5CCCc(c53)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C04 compound treatment 662158.0 202000.0 0.42 676126.0 201000.0 0.43 0.6021 0.9998 1947990 ChemDiv1_023280 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(Cl)c(Cl)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C05 compound treatment 744157.0 284000.0 0.59 755068.0 280000.0 0.61 0.8426 0.9999 1337950 ChemDiv1_023281 O=c1n(Cc2ccccc2)cnc3c(C#N)c4CCCCn4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C06 compound treatment 722249.0 262000.0 0.54 698009.0 223000.0 0.48 0.7233 0.9983 1980611 ChemDiv1_023282 COC(=O)C1=C(S/C(=C\2/C(=S)C(C)(C)N(C(=O)C)c3c(C)cc(C)cc23)/S1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C07 compound treatment 742400.0 282000.0 0.58 740049.0 265000.0 0.57 0.817 1.0 1522363 ChemDiv1_023283 NC1=C(C(C2=C(CCCC2=O)N1c3ccccc3)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C08 compound treatment 735699.0 276000.0 0.57 731185.0 256000.0 0.55 0.7937 0.9999 1586732 ChemDiv1_023284 COc1cc(ccc1OC(=O)C)C2C3=C(N(C(=O)C)c4c2c(=O)n(C)c(=O)n4C)c5ccccc5C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C09 compound treatment 740549.0 281000.0 0.58 783965.0 308000.0 0.67 0.8815 0.9975 1648943 ChemDiv1_023285 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4)C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C10 compound treatment 745900.0 286000.0 0.59 719931.0 244000.0 0.53 0.7913 0.9985 1632677 ChemDiv1_023286 CCNC(=S)N1CCN(CCNC2=CC(=O)CC(C)(C)C2)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C11 compound treatment 737492.0 277000.0 0.57 740179.0 265000.0 0.57 0.8101 1.0 1164372 ChemDiv1_023287 CC(C)OC(=O)C1=C(C)NC(=O)CC1c2ccc(Cl)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C12 compound treatment 761220.0 301000.0 0.62 720673.0 245000.0 0.53 0.8148 0.9969 1691873 ChemDiv1_023288 COc1cc2CC3(CCCC3)N=C(c4ccccc4)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C13 compound treatment 775005.0 315000.0 0.65 756595.0 281000.0 0.61 0.8899 0.9994 1160638 ChemDiv1_023289 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccccc4)cc3)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C14 compound treatment 750844.0 291000.0 0.6 765963.0 290000.0 0.63 0.869 0.9997 1735207 ChemDiv1_023290 Fc1ccc(NC(=S)N2CCCc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C15 compound treatment 782477.0 322000.0 0.67 772920.0 297000.0 0.64 0.9258 0.9999 1219631 ChemDiv1_023291 CCOC(=O)c1c(NC(=O)c2c(C)onc2c3ccccc3Cl)sc4CCCCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C16 compound treatment 785675.0 326000.0 0.67 747906.0 272000.0 0.59 0.8922 0.9979 1946108 ChemDiv1_023292 CN(C)c1ccc(cc1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C17 compound treatment 795893.0 336000.0 0.69 779110.0 304000.0 0.66 0.9549 0.9996 1425618 ChemDiv1_023293 CC(Oc1ccc2c3CCCCc3c(=O)oc2c1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C18 compound treatment 751558.0 292000.0 0.6 680565.0 205000.0 0.44 0.7394 0.9888 1946251 ChemDiv1_023294 COc1ccc(OC)c(c1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C19 compound treatment 848993.0 389000.0 0.8 805169.0 330000.0 0.71 1.0723 0.9983 1945988 ChemDiv1_023295 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3cccc(O)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C20 compound treatment 785751.0 326000.0 0.67 710842.0 235000.0 0.51 0.8356 0.9906 1453404 ChemDiv1_023296 COCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(OC)cc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C21 compound treatment 767578.0 308000.0 0.63 757963.0 282000.0 0.61 0.8812 0.9998 1948089 ChemDiv1_023297 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(F)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C22 compound treatment 724999.0 265000.0 0.55 669099.0 194000.0 0.42 0.683 0.9913 1980612 ChemDiv1_023298 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4[N+](=O)[O-])c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C23 mock treatment 694209.0 234000.0 0.48 663637.0 188000.0 0.41 0.6297 0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 C24 mock treatment 220784.0 -239000.0 -0.49 230031.0 -245000.0 -0.53 -0.7249 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D01 compound treatment 669572.0 210000.0 0.43 605574.0 130000.0 0.28 0.5049 0.9784 1709788 ChemDiv1_023299 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(cc3)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D02 compound treatment 643925.0 184000.0 0.38 636127.0 161000.0 0.35 0.5142 0.999 1980613 ChemDiv1_023300 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4cccc(c4)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D03 compound treatment 705423.0 245000.0 0.51 685666.0 210000.0 0.45 0.6798 0.9986 1260422 ChemDiv1_023301 CCOC(=O)c1nnn(c1CN2CCOCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D04 compound treatment 695470.0 235000.0 0.49 661422.0 186000.0 0.4 0.6282 0.9956 1980614 ChemDiv1_023302 CC1CCN(CC(=O)N2c3ccccc3CCc4ccccc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D05 compound treatment 739556.0 280000.0 0.58 668052.0 193000.0 0.42 0.7027 0.9872 1980615 ChemDiv1_023303 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3cccc(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D06 compound treatment 616822.0 157000.0 0.32 533461.0 58000.0 0.13 0.3175 0.9149 1536067 ChemDiv1_023304 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D07 compound treatment 748713.0 289000.0 0.6 726243.0 251000.0 0.54 0.8051 0.9989 1941324 ChemDiv1_023305 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccccc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D08 compound treatment 726079.0 266000.0 0.55 714447.0 239000.0 0.52 0.754 0.9995 1690313 ChemDiv1_023306 COc1cc(C2CC(=O)Nc3c2ccc4ccccc34)c(OC)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D09 compound treatment 731500.0 271000.0 0.56 722713.0 247000.0 0.54 0.7746 0.9997 1462643 ChemDiv1_023307 CCCN1C2NC(=O)N(CCC)C2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D10 compound treatment 725157.0 265000.0 0.55 720184.0 245000.0 0.53 0.7615 0.9999 1704673 ChemDiv1_023308 CC1(C)Cc2nc(N)c(cc2CO1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D11 compound treatment 733897.0 274000.0 0.57 717277.0 242000.0 0.52 0.7698 0.9993 1446984 ChemDiv1_023309 CC1CCc2oc3c(cc(NS(=O)(=O)c4ccc(C)cc4)c5ccccc35)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D12 compound treatment 753154.0 293000.0 0.61 684659.0 209000.0 0.45 0.748 0.9898 1980616 ChemDiv1_023310 CCCCCNc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D13 compound treatment 786335.0 326000.0 0.67 739470.0 264000.0 0.57 0.8803 0.9966 1223883 ChemDiv1_023311 NC(=O)N1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D14 compound treatment 788177.0 328000.0 0.68 848442.0 373000.0 0.81 1.0497 0.9962 1980617 ChemDiv1_023312 CCC1(C)CC(CCNCc2ccc(OC)cc2)(CCO1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D15 compound treatment 786533.0 326000.0 0.67 782781.0 307000.0 0.67 0.9468 1.0 1423085 ChemDiv1_023313 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(OCC(=O)O)cc4)ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D16 compound treatment 824703.0 365000.0 0.75 769579.0 294000.0 0.64 0.9824 0.9965 1980618 ChemDiv1_023314 C1CCC(CC1)Nc2nnnc3c2sc4nc(N5CCOCC5)c6CCCCc6c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D17 compound treatment 934120.0 474000.0 0.98 819341.0 344000.0 0.74 1.2182 0.9909 1430854 ChemDiv1_023315 COc1ccccc1N(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D18 compound treatment 671773.0 212000.0 0.44 700472.0 225000.0 0.49 0.6534 0.9985 1709337 ChemDiv1_023316 COc1ccc(cc1)C2OCC3C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D19 compound treatment 765623.0 306000.0 0.63 688990.0 213000.0 0.46 0.7728 0.9883 1222347 ChemDiv1_023317 COc1ccccc1N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D20 compound treatment 716346.0 256000.0 0.53 765010.0 290000.0 0.63 0.8172 0.9965 1350016 ChemDiv1_023318 CCCNC(=O)OCC1(COC2C3C1C)C(C)CC3(C)Oc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D21 compound treatment 752220.0 292000.0 0.6 699664.0 224000.0 0.49 0.7696 0.9942 1980619 ChemDiv1_023319 CCOC(=O)c1cnc2ccccc2c1Nc3cccc(c3)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D22 compound treatment 734831.0 275000.0 0.57 750809.0 275000.0 0.6 0.8224 0.9997 1980620 ChemDiv1_023320 COc1ccc(CN2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-])cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D23 mock treatment 699674.0 240000.0 0.49 639694.0 164000.0 0.36 0.6011 0.9868 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 D24 mock treatment 217266.0 -243000.0 -0.5 264032.0 -211000.0 -0.46 -0.678 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E01 compound treatment 656822.0 197000.0 0.41 623014.0 148000.0 0.32 0.513 0.9929 1279413 ChemDiv1_023321 O=c1n2CCCc2nc3sc4CCCCc4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E02 compound treatment 734608.0 275000.0 0.57 721702.0 246000.0 0.53 0.7776 0.9995 1980621 ChemDiv1_023322 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(F)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E03 compound treatment 674849.0 215000.0 0.44 672465.0 197000.0 0.43 0.615 0.9998 1238020 ChemDiv1_023323 Clc1ccc(s1)C(=C2CN3CCC2CC3)c4ccc(Cl)s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E04 compound treatment 2027280.0 1570000.0 3.24 2938867.0 2460000.0 5.33 6.0577 0.9713 1949209 ChemDiv1_023324 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E05 compound treatment 684518.0 224000.0 0.46 650815.0 175000.0 0.38 0.596 0.9951 1916552 ChemDiv1_023325 CN(C)/C=C\1/N=C(c2ccccc2)c3cc(Cl)ccc3N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E06 compound treatment 704749.0 245000.0 0.51 672793.0 197000.0 0.43 0.6591 0.9965 1980622 ChemDiv1_023326 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccccc3)c4ccc(OC(=O)c5ccccc5)cc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E07 compound treatment 758570.0 299000.0 0.62 752913.0 277000.0 0.6 0.8603 0.9999 1980623 ChemDiv1_023327 NC1=C(C(C2=C(CCCC2=O)N1c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E08 compound treatment 607610.0 148000.0 0.3 578308.0 103000.0 0.22 0.3727 0.9881 1980624 ChemDiv1_023328 Oc1cccc(c1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E09 compound treatment 741276.0 281000.0 0.58 748533.0 273000.0 0.59 0.8284 1.0 1980625 ChemDiv1_023329 COc1ccc(OC)c(c1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E10 compound treatment 791228.0 331000.0 0.68 782148.0 307000.0 0.66 0.9527 0.9999 1709056 ChemDiv1_023330 CCOc1cc(C=c2sc3nc(nn3c2=O)c4ccc(Cl)cc4)ccc1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E11 compound treatment 748597.0 289000.0 0.6 757171.0 282000.0 0.61 0.8523 0.9999 1194074 ChemDiv1_023331 CCOC(=O)Cc1nnc2c(nc3nonc3n12)N(CC)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E12 compound treatment 787026.0 327000.0 0.67 763352.0 288000.0 0.62 0.9178 0.9992 1980626 ChemDiv1_023332 COc1cc2CC3(CCCC3)N/C(=N\c4ccc(F)c(F)c4)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E13 compound treatment 655514.0 195000.0 0.4 636215.0 161000.0 0.35 0.5313 0.9973 1681329 ChemDiv1_023333 Cn1c2NC3=C(C(c4ccc(OCc5ccccc5)cc4)c2c(=O)[nH]c1=O)C(=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E14 compound treatment 720184.0 260000.0 0.54 673789.0 198000.0 0.43 0.6832 0.9938 1302024 ChemDiv1_023334 O=C(C(c1ccccc1)c2ccccc2)N3CCCc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E15 compound treatment 768746.0 309000.0 0.64 795525.0 320000.0 0.69 0.9404 0.9991 1926441 ChemDiv1_023335 CCOc1ccccc1NC(=O)c2cc(ccc2N3CCN(Cc4ccccc4)CC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E16 compound treatment 751161.0 291000.0 0.6 691245.0 216000.0 0.47 0.7551 0.9922 1945654 ChemDiv1_023336 [O-][N+](=O)c1ccccc1C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E17 compound treatment 1.1518916E7 1.11E7 22.83 2297456.0 1820000.0 3.94 18.9309 0.8171 1948151 ChemDiv1_023337 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(cc3)N(CC)CC)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E18 compound treatment 752583.0 293000.0 0.6 706238.0 231000.0 0.5 0.7801 0.9955 1980627 ChemDiv1_023338 COc1cc(ccc1O)C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E19 compound treatment 882752.0 423000.0 0.87 800428.0 325000.0 0.7 1.1143 0.9943 1948206 ChemDiv1_023339 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(F)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E20 compound treatment 780831.0 321000.0 0.66 714124.0 239000.0 0.52 0.8334 0.9924 1280389 ChemDiv1_023340 COCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(O)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E21 compound treatment 796918.0 337000.0 0.7 757320.0 282000.0 0.61 0.923 0.9979 1948096 ChemDiv1_023341 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E22 compound treatment 746067.0 286000.0 0.59 697042.0 222000.0 0.48 0.7566 0.9947 1492199 ChemDiv1_023342 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccc5OCOc5c4)c6ccc(F)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E23 mock treatment 702568.0 243000.0 0.5 666842.0 191000.0 0.41 0.6468 0.9956 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 E24 mock treatment 272221.0 -188000.0 -0.39 233350.0 -242000.0 -0.52 -0.6448 -0.989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F01 compound treatment 659128.0 199000.0 0.41 614219.0 139000.0 0.3 0.5029 0.9881 1722137 ChemDiv1_023343 CC(C)c1ccc(cc1)C2N(CCN(C)C)C(=O)C(=C2C(=O)c3ccccc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F02 compound treatment 681583.0 222000.0 0.46 666410.0 191000.0 0.41 0.6156 0.9987 1164236 ChemDiv1_023344 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4cccc(c4)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F03 compound treatment 670815.0 211000.0 0.44 704687.0 229000.0 0.5 0.6584 0.9979 1248881 ChemDiv1_023345 CCOC(=O)c1nnn(c1CN2CCC(=O)CC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F04 compound treatment 679252.0 219000.0 0.45 656004.0 181000.0 0.39 0.5962 0.9973 1122967 ChemDiv1_023346 Cc1cc(C)c2N(C(=O)CN3C(=O)c4ccccc4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F05 compound treatment 731156.0 271000.0 0.56 700243.0 225000.0 0.49 0.7397 0.9976 1980628 ChemDiv1_023347 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(cc3)[N+](=O)[O-])/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F06 compound treatment 712379.0 252000.0 0.52 644229.0 169000.0 0.37 0.6266 0.9849 1660899 ChemDiv1_023348 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccc(O)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F07 compound treatment 738922.0 279000.0 0.58 707507.0 232000.0 0.5 0.7621 0.9977 1980629 ChemDiv1_023349 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(OC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F08 compound treatment 743246.0 283000.0 0.58 707310.0 232000.0 0.5 0.7682 0.9971 1527133 ChemDiv1_023350 OC(CN1CCN(CC1)c2ccccc2)Cn3c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F09 compound treatment 803092.0 343000.0 0.71 749241.0 274000.0 0.59 0.9197 0.9961 1980630 ChemDiv1_023351 CCOc1ccccc1NC(=O)C2=C(C)NC(=S)NC2c3c(OC)ccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F10 compound treatment 752331.0 292000.0 0.6 746344.0 271000.0 0.59 0.8412 0.9999 1941849 ChemDiv1_023352 CC1(C)Cc2c(CO1)sc3[nH]c(=S)[nH]c(=S)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F11 compound treatment 754696.0 295000.0 0.61 700339.0 225000.0 0.49 0.7742 0.9939 1980631 ChemDiv1_023353 CCCCN(CCCC)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F12 compound treatment 718174.0 258000.0 0.53 704162.0 229000.0 0.49 0.7267 0.9993 1399667 ChemDiv1_023354 CCN(CC)c1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F13 compound treatment 750494.0 290000.0 0.6 699208.0 224000.0 0.48 0.7663 0.9944 1165417 ChemDiv1_023355 CC(C)COc1ccc2n3CCNC4CCCc(c43)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F14 compound treatment 830044.0 370000.0 0.76 807615.0 332000.0 0.72 1.0484 0.9995 1942058 ChemDiv1_023356 CCC1(C)CC(CCNCc2ccc(F)cc2)(CCO1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F15 compound treatment 813237.0 353000.0 0.73 776814.0 301000.0 0.65 0.9767 0.9985 1980632 ChemDiv1_023357 Cn1c(=O)n(C)c2nc(Cl)n(CC(=O)c3ccc(cc3)[N+](=O)[O-])c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F16 compound treatment 787727.0 328000.0 0.68 815704.0 340000.0 0.74 0.999 0.9991 1534800 ChemDiv1_023358 CN(C)c1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F17 compound treatment 802752.0 343000.0 0.71 740571.0 265000.0 0.57 0.9059 0.9946 1980633 ChemDiv1_023359 COCc1cc(C)nc2sc3c(=O)[nH]nnc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F18 compound treatment 791098.0 331000.0 0.68 767260.0 292000.0 0.63 0.9298 0.9992 1607541 ChemDiv1_023360 CC1C=C(C)C2C(C)C1(CO)COC2c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F19 compound treatment 865252.0 405000.0 0.84 794144.0 319000.0 0.69 1.0791 0.9954 1697170 ChemDiv1_023361 COc1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F20 compound treatment 735615.0 276000.0 0.57 741134.0 266000.0 0.57 0.8088 1.0 1562226 ChemDiv1_023362 CCC(=O)Oc1ccccc1C2OCC3C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F21 compound treatment 799585.0 340000.0 0.7 725467.0 250000.0 0.54 0.8782 0.9918 1272394 ChemDiv1_023363 CCOC(=O)c1cnc2ccccc2c1Nc3cccc(c3)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F22 compound treatment 713691.0 254000.0 0.52 732628.0 257000.0 0.56 0.7638 0.9995 1980634 ChemDiv1_023364 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3cccc(OC)c3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F23 mock treatment 713559.0 254000.0 0.52 660748.0 185000.0 0.4 0.6536 0.9913 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 F24 mock treatment 214606.0 -245000.0 -0.51 248262.0 -227000.0 -0.49 -0.706 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G01 compound treatment 652329.0 192000.0 0.4 589686.0 114000.0 0.25 0.4554 0.974 1499569 ChemDiv1_023365 COc1cc(ccc1O)C2N3CC4(C)CN2CC(C)(C3)C4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G02 compound treatment 711539.0 251000.0 0.52 741180.0 266000.0 0.58 0.7737 0.9987 1980635 ChemDiv1_023366 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G03 compound treatment 682823.0 223000.0 0.46 706782.0 231000.0 0.5 0.6791 0.9991 1235538 ChemDiv1_023367 OC12Oc3ccccc3C=C2N4CCC1CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G04 compound treatment 705418.0 245000.0 0.51 705861.0 230000.0 0.5 0.7107 1.0 1949169 ChemDiv1_023368 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(cc3)[N+](=O)[O-])/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G05 compound treatment 727475.0 267000.0 0.55 705727.0 230000.0 0.5 0.7427 0.9987 1550390 ChemDiv1_023369 CCSc1ncnc2c(C#N)c3CCCCCn3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G06 compound treatment 662712.0 203000.0 0.42 687978.0 212000.0 0.46 0.621 0.9989 1924995 ChemDiv1_023370 CCOC(=O)C1=CS/C(=C\2/C(=S)C(C)(C)Nc3cc(C)ccc23)/S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G07 compound treatment 825331.0 365000.0 0.75 829203.0 354000.0 0.77 1.0745 1.0 1572621 ChemDiv1_023371 Cc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccccc4)C(=O)CCC3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G08 compound treatment 617213.0 157000.0 0.32 618693.0 143000.0 0.31 0.4486 0.9997 1171760 ChemDiv1_023372 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccc(O)c4)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G09 compound treatment 754078.0 294000.0 0.61 737927.0 262000.0 0.57 0.8308 0.9995 1180443 ChemDiv1_023373 COc1cccc2c1oc(=O)c3c(N)nc4CCCCc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G10 compound treatment 883292.0 423000.0 0.87 893987.0 418000.0 0.91 1.2583 0.9998 1980636 ChemDiv1_023374 CN(C)c1ccc(C=c2sc3nc(nn3c2=O)c4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G11 compound treatment 761227.0 301000.0 0.62 729537.0 254000.0 0.55 0.8284 0.9981 1477700 ChemDiv1_023375 CCOC(=O)Cc1nnc2c(Nc3ccccc3C)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G12 compound treatment 732772.0 273000.0 0.56 729531.0 254000.0 0.55 0.7869 0.9999 1980637 ChemDiv1_023376 COc1cc2CC(C)(C)N/C(=N\c3cc(C)ccc3C)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G13 compound treatment 693944.0 234000.0 0.48 690780.0 215000.0 0.47 0.6709 0.9998 1247231 ChemDiv1_023377 COc1ccc(OC)c(c1)C2C3=C(Nc4c2c(=O)[nH]c(=O)n4C)c5ccccc5C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G14 compound treatment 929487.0 469000.0 0.97 946480.0 471000.0 1.02 1.406 0.9997 1223049 ChemDiv1_023378 CCn1c2ccccc2c3cc(ccc13)C4C5CCCC=C5C(=C(N)C4(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G15 compound treatment 964383.0 504000.0 1.04 943222.0 468000.0 1.01 1.452 0.9999 1738152 ChemDiv1_023379 CC(=O)Nc1ccccc1c2n[nH]c(=S)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G16 compound treatment 877933.0 418000.0 0.86 811480.0 336000.0 0.73 1.1242 0.9964 1400506 ChemDiv1_023380 COCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G17 compound treatment 783723.0 324000.0 0.67 762194.0 287000.0 0.62 0.9112 0.9993 1941715 ChemDiv1_023381 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccccc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G18 compound treatment 749561.0 290000.0 0.6 701496.0 226000.0 0.49 0.7685 0.9951 1980638 ChemDiv1_023382 COc1ccc(C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G19 compound treatment 1331292.0 871000.0 1.8 1126443.0 651000.0 1.41 2.268 0.9927 1942894 ChemDiv1_023383 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(O)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G20 compound treatment 722800.0 263000.0 0.54 669772.0 194000.0 0.42 0.6809 0.9921 1435005 ChemDiv1_023384 O=C1N(C(c2c(n[nH]c12)c3ccccc3)c4ccc5OCOc5c4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G21 compound treatment 701572.0 242000.0 0.5 736767.0 261000.0 0.57 0.7524 0.998 1948330 ChemDiv1_023385 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(O)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G22 compound treatment 740065.0 280000.0 0.58 673295.0 198000.0 0.43 0.7115 0.9891 1648770 ChemDiv1_023386 Cc1ccc(cc1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G23 mock treatment 689339.0 229000.0 0.47 699826.0 224000.0 0.49 0.678 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 G24 mock treatment 217517.0 -243000.0 -0.5 260577.0 -215000.0 -0.47 -0.6829 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H01 compound treatment 634487.0 174000.0 0.36 594495.0 119000.0 0.26 0.4367 0.9865 1620932 ChemDiv1_023387 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H02 compound treatment 659555.0 200000.0 0.41 662080.0 187000.0 0.4 0.5768 1.0 1661772 ChemDiv1_023388 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4ccc(cc4)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H03 compound treatment 729962.0 270000.0 0.56 708723.0 233000.0 0.5 0.7509 0.9988 1295069 ChemDiv1_023389 COC(=O)c1nnn(c1CN2CCCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H04 compound treatment 677935.0 218000.0 0.45 646676.0 171000.0 0.37 0.58 0.9954 1980639 ChemDiv1_023390 COc1ccc2N(C(=O)CN3CCC(C)CC3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H05 compound treatment 749689.0 290000.0 0.6 708770.0 233000.0 0.5 0.7798 0.9965 1931534 ChemDiv1_023391 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3cccc(O)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H06 compound treatment 668001.0 208000.0 0.43 665642.0 190000.0 0.41 0.5946 0.9998 1980640 ChemDiv1_023392 Cc1ccc(cc1)N2C(=O)CC(C3=C2CC(C)(C)CC3=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H07 compound treatment 770384.0 310000.0 0.64 724640.0 249000.0 0.54 0.8343 0.9963 1980641 ChemDiv1_023393 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3cccc(O)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H08 compound treatment 766833.0 307000.0 0.63 665968.0 190000.0 0.41 0.7393 0.9784 1637475 ChemDiv1_023394 CC(=O)N1CCN(CC(O)Cn2c3ccccc3c4ccccc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H09 compound treatment 689812.0 230000.0 0.47 649711.0 174000.0 0.38 0.602 0.9935 1980642 ChemDiv1_023395 COc1ccc2ccccc2c1C3NC(=S)NC(=C3C(=O)Nc4cccc(C)c4C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H10 compound treatment 788783.0 329000.0 0.68 739374.0 264000.0 0.57 0.8837 0.9963 1486749 ChemDiv1_023396 C1CCN(CC1)c2ncnc3c2sc4nc(N5CCOCC5)c6CCCCc6c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H11 compound treatment 685023.0 225000.0 0.46 699513.0 224000.0 0.48 0.6712 0.9998 1256379 ChemDiv1_023397 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H12 compound treatment 721325.0 261000.0 0.54 691532.0 216000.0 0.47 0.712 0.9975 1580764 ChemDiv1_023398 CCOc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H13 compound treatment 707066.0 247000.0 0.51 696473.0 221000.0 0.48 0.6988 0.9995 1430581 ChemDiv1_023399 C1CCC(CC1)c2ccc3n4CCNC5CCCc(c54)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H14 compound treatment 808522.0 348000.0 0.72 758218.0 283000.0 0.61 0.9414 0.9968 1941459 ChemDiv1_023400 CCC1(C)CC(CCNCc2ccc(cc2)N(C)C)(CCO1)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H15 compound treatment 789150.0 329000.0 0.68 738508.0 263000.0 0.57 0.8829 0.9961 1980643 ChemDiv1_023401 CC1(C)CC2(CC(C)(C)OC2=O)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H16 compound treatment 794837.0 335000.0 0.69 758296.0 283000.0 0.61 0.9215 0.9982 1980644 ChemDiv1_023402 Brc1cccc(/C=C(/NC(=O)c2ccccc2)\C(=O)NCc3ccco3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H17 compound treatment 949972.0 490000.0 1.01 870403.0 395000.0 0.85 1.3195 0.9965 1315290 ChemDiv1_023403 Cc1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H18 compound treatment 749864.0 290000.0 0.6 739992.0 264000.0 0.57 0.8278 0.9998 1122916 ChemDiv1_023404 CC1C=C(C)C2C(C)C1(CO)COC2c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H19 compound treatment 785714.0 326000.0 0.67 697177.0 222000.0 0.48 0.8146 0.9863 1621934 ChemDiv1_023405 CCOc1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H20 compound treatment 726883.0 267000.0 0.55 718174.0 243000.0 0.53 0.7609 0.9997 1280381 ChemDiv1_023406 COc1cc(ccc1OC(=O)C)C2OCC3(COC(=O)C)C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H21 compound treatment 756121.0 296000.0 0.61 676263.0 201000.0 0.43 0.7394 0.986 1264302 ChemDiv1_023407 CCOC(=O)c1cnc2ccccc2c1Nc3ccc(cc3)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H22 compound treatment 723857.0 264000.0 0.54 693689.0 218000.0 0.47 0.719 0.9975 1980645 ChemDiv1_023408 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccc(F)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H23 mock treatment 707943.0 248000.0 0.51 654023.0 179000.0 0.39 0.6351 0.9904 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 H24 mock treatment 238251.0 -222000.0 -0.46 249655.0 -226000.0 -0.49 -0.6694 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I01 compound treatment 641608.0 182000.0 0.37 589729.0 114000.0 0.25 0.4398 0.9796 1784365 ChemDiv1_023409 COc1ccc(cc1)C2N3CC4(CN2CC(C3)([N+](=O)[O-])C4(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I02 compound treatment 1388406.0 928000.0 1.92 1582284.0 1110000.0 2.4 3.049 0.9939 1950554 ChemDiv1_023410 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I03 compound treatment 696137.0 236000.0 0.49 704157.0 229000.0 0.49 0.6946 1.0 1980646 ChemDiv1_023411 N#C/C(=C/1\CCCCCN1)/c2nnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I04 compound treatment 668673.0 209000.0 0.43 683113.0 208000.0 0.45 0.6223 0.9998 1947911 ChemDiv1_023412 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(O)c(OCC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I05 compound treatment 750564.0 291000.0 0.6 716447.0 241000.0 0.52 0.7928 0.9976 1639681 ChemDiv1_023413 COC(=O)Cn1cnc2c(C#N)c3CCCCCn3c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I06 compound treatment 728589.0 269000.0 0.55 643117.0 168000.0 0.36 0.6485 0.9789 1980647 ChemDiv1_023414 CC1CCN(CC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I07 compound treatment 722113.0 262000.0 0.54 709650.0 234000.0 0.51 0.7409 0.9995 1322612 ChemDiv1_023415 Cc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I08 compound treatment 730426.0 270000.0 0.56 748103.0 273000.0 0.59 0.8119 0.9996 1980648 ChemDiv1_023416 COc1cc(ccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(C)cc6)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I09 compound treatment 748724.0 289000.0 0.6 700849.0 225000.0 0.49 0.7663 0.9951 1980649 ChemDiv1_023417 COC(=O)C1CC(=O)OC21CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I10 compound treatment 741926.0 282000.0 0.58 747825.0 272000.0 0.59 0.8282 1.0 1980650 ChemDiv1_023418 COc1ccc(C=c2sc3nc(nn3c2=O)c4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I11 compound treatment 733975.0 274000.0 0.57 729311.0 254000.0 0.55 0.7883 0.9999 1573701 ChemDiv1_023419 CC1C(O)CC(NC1c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I12 compound treatment 734730.0 275000.0 0.57 695229.0 220000.0 0.48 0.7372 0.9962 1980651 ChemDiv1_023420 COc1cc2CC(C)(C)N/C(=N\c3ccc(Cl)c(Cl)c3)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I13 compound treatment 726330.0 266000.0 0.55 742983.0 267000.0 0.58 0.7981 0.9997 1980652 ChemDiv1_023421 Cn1c2NC3=C(C(c4ccc(o4)[N+](=O)[O-])c2c(=O)[nH]c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I14 compound treatment 889612.0 430000.0 0.89 831109.0 356000.0 0.77 1.1713 0.9975 1734106 ChemDiv1_023422 NC1=C(C#N)C2=CCCCC2C(c3ccc[nH]3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I15 compound treatment 769432.0 309000.0 0.64 710529.0 235000.0 0.51 0.8113 0.9936 1433347 ChemDiv1_023423 CCN(CC)C(=O)CSc1nnc(c2ccccc2)c(n1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I16 compound treatment 736665.0 277000.0 0.57 693123.0 218000.0 0.47 0.7368 0.9954 1355028 ChemDiv1_023424 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I17 compound treatment 788190.0 328000.0 0.68 810036.0 335000.0 0.72 0.991 0.9994 1980653 ChemDiv1_023425 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(cc3)[N+](=O)[O-])/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I18 compound treatment 730907.0 271000.0 0.56 672719.0 197000.0 0.43 0.6972 0.9911 1980654 ChemDiv1_023426 COc1ccccc1C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I19 compound treatment 721497.0 261000.0 0.54 704841.0 229000.0 0.5 0.7326 0.9991 1946194 ChemDiv1_023427 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccccc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I20 compound treatment 727277.0 267000.0 0.55 681564.0 206000.0 0.45 0.7054 0.9944 1304706 ChemDiv1_023428 COc1ccccc1C2N(C(=O)c3[nH]nc(c23)c4ccc(C)cc4)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I21 compound treatment 784378.0 324000.0 0.67 722064.0 247000.0 0.53 0.8508 0.9937 1946098 ChemDiv1_023429 CCOC(=O)C1=C(Nc2cccc3ccccc23)S/C(=C\c4ccc(cc4)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I22 compound treatment 712532.0 252000.0 0.52 591794.0 116000.0 0.25 0.5465 0.9442 1522865 ChemDiv1_023430 Clc1ccc(C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I23 mock treatment 713586.0 254000.0 0.52 678002.0 203000.0 0.44 0.68 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 I24 mock treatment 243194.0 -217000.0 -0.45 239811.0 -236000.0 -0.51 -0.6772 -0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J01 compound treatment 828819.0 369000.0 0.76 699618.0 224000.0 0.49 0.8813 0.9763 1599653 ChemDiv1_023431 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J02 compound treatment 643070.0 183000.0 0.38 645120.0 170000.0 0.37 0.5268 0.9999 1445367 ChemDiv1_023432 CCOC(=O)c1ccc(Nc2c(cnc3c2ccc4ccccc43)C(=O)OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J03 compound treatment 713243.0 253000.0 0.52 683326.0 208000.0 0.45 0.6877 0.9972 1118233 ChemDiv1_023433 COC(=O)c1nnn(c1CN2CCC(C)CC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J04 compound treatment 677764.0 218000.0 0.45 651720.0 176000.0 0.38 0.5875 0.9967 1611239 ChemDiv1_023434 Cc1ccc(cc1)C(=O)Oc2cccc(c2)C3C4=C(Nc5c3c(=O)[nH]c(=O)n5C)c6ccccc6C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J05 compound treatment 646612.0 187000.0 0.39 721665.0 246000.0 0.53 0.6491 0.9873 1931503 ChemDiv1_023435 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J06 compound treatment 700624.0 241000.0 0.5 678493.0 203000.0 0.44 0.6618 0.9981 1401011 ChemDiv1_023436 COc1ccc(cc1)N2C(=O)CC(C3=C2CC(C)(C)CC3=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J07 compound treatment 750010.0 290000.0 0.6 671557.0 196000.0 0.42 0.7233 0.9858 1980655 ChemDiv1_023437 Cc1ccc(cc1Cl)C2OC(=O)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J08 compound treatment 662976.0 203000.0 0.42 669075.0 194000.0 0.42 0.5925 1.0 1296146 ChemDiv1_023438 CCN(C(=O)C1C2CC(C)(NC1=O)Oc3ccccc23)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J09 compound treatment 803279.0 343000.0 0.71 760190.0 285000.0 0.62 0.9367 0.9976 1980656 ChemDiv1_023439 COc1cccc(C2NC(=S)NC(=C2C(=O)Nc3cccc(C)c3C)C)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J10 compound treatment 752179.0 292000.0 0.6 757492.0 282000.0 0.61 0.858 1.0 1477406 ChemDiv1_023440 CCOc1ncnc2c1sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J11 compound treatment 726736.0 267000.0 0.55 753925.0 278000.0 0.6 0.8154 0.999 1505274 ChemDiv1_023441 Cn1c(Br)nc2n(C)c(=O)n(Cc3ccccc3Cl)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J12 compound treatment 778299.0 318000.0 0.66 767260.0 292000.0 0.63 0.9111 0.9998 1694750 ChemDiv1_023442 CC1(C)Cc2c(CO1)c(nc3sc4c(NCC=C)ncnc4c23)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J13 compound treatment 716345.0 256000.0 0.53 715745.0 240000.0 0.52 0.7418 1.0 1919813 ChemDiv1_023443 C1CC2NCCn3c2c(C1)c4cc(ccc34)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J14 compound treatment 722021.0 262000.0 0.54 672362.0 197000.0 0.43 0.6837 0.993 1980657 ChemDiv1_023444 CCC1(C)CC(CCNCc2ccc(F)cc2)(CCO1)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J15 compound treatment 810219.0 350000.0 0.72 781330.0 306000.0 0.66 0.9792 0.999 1980658 ChemDiv1_023445 CCN(CC)C(=O)/C(=C/c1cccc(c1)[N+](=O)[O-])/NC(=O)c2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J16 compound treatment 731749.0 272000.0 0.56 699086.0 224000.0 0.48 0.7388 0.9973 1222045 ChemDiv1_023446 COc1ccc(cc1)C2OCC3(COC(=O)C)C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J17 compound treatment 797063.0 337000.0 0.7 751435.0 276000.0 0.6 0.9142 0.9971 1645822 ChemDiv1_023447 Cc1cc(=O)oc2c3CN(COc3ccc12)c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J18 compound treatment 726970.0 267000.0 0.55 721045.0 246000.0 0.53 0.7654 0.9998 1294445 ChemDiv1_023448 COc1cc(ccc1O)C2OCC3(CO)C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J19 compound treatment 776196.0 316000.0 0.65 668848.0 193000.0 0.42 0.7574 0.9769 1656969 ChemDiv1_023449 CCOC(=O)c1cnc2ccccc2c1Nc3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J20 compound treatment 725288.0 265000.0 0.55 712637.0 237000.0 0.51 0.7501 0.9995 1424448 ChemDiv1_023450 Fc1ccc(cc1)C2N(CCN2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J21 compound treatment 778004.0 318000.0 0.66 685399.0 210000.0 0.45 0.7854 0.9839 1246220 ChemDiv1_023451 CCOC(=O)c1cnc2ccccc2c1Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J22 compound treatment 710670.0 251000.0 0.52 688552.0 213000.0 0.46 0.6919 0.9984 1529164 ChemDiv1_023452 CCc1nc2CC(C)(C)CC(=O)c2c3c4ccccc4[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J23 mock treatment 708910.0 249000.0 0.51 648502.0 173000.0 0.37 0.628 0.9879 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 J24 mock treatment 229130.0 -231000.0 -0.48 228481.0 -247000.0 -0.53 -0.7151 -0.9984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K01 compound treatment 696047.0 236000.0 0.49 593734.0 118000.0 0.26 0.5254 0.9548 1783793 ChemDiv1_023453 CC1(C)C2(CN3CC1(CN(C2)C3c4ccc(Cl)cc4)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K02 compound treatment 1416342.0 956000.0 1.97 1573953.0 1100000.0 2.38 3.077 0.9957 1945675 ChemDiv1_023454 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K03 compound treatment 675818.0 216000.0 0.45 678393.0 203000.0 0.44 0.6255 1.0 1947090 ChemDiv1_023455 [O-][N+](=O)c1ccc(cc1)n2c(=O)c(C#N)cc3[nH]c4ccccc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K04 compound treatment 659217.0 199000.0 0.41 657403.0 182000.0 0.39 0.5691 0.9998 1980659 ChemDiv1_023456 CC1CCN(CC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccc(Cl)cc4)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K05 compound treatment 691334.0 231000.0 0.48 702547.0 227000.0 0.49 0.6851 0.9999 1322823 ChemDiv1_023457 COc1ccc(cc1)C(=O)Cn2cnc3c(C#N)c4CCCCCn4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K06 compound treatment 696578.0 237000.0 0.49 690439.0 215000.0 0.47 0.6742 0.9997 1924425 ChemDiv1_023458 Cc1cc(C)nc(SCC(=O)N2c3ccccc3-c4c(ssc4=S)C2(C)C)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K07 compound treatment 747830.0 288000.0 0.59 767291.0 292000.0 0.63 0.8666 0.9995 1851972 ChemDiv1_023459 Cc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc(cc4)[N+](=O)[O-])C(=O)CCC3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K08 compound treatment 721476.0 261000.0 0.54 721336.0 246000.0 0.53 0.7578 1.0 1870740 ChemDiv1_023460 CCCCC(=O)N1C2=C(C(c3cccc(c3)[N+](=O)[O-])c4c1n(C)c(=O)n(C)c4=O)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K09 compound treatment 797788.0 338000.0 0.7 825684.0 350000.0 0.76 1.0289 0.9991 1980660 ChemDiv1_023461 Oc1ccccc1C2=Nc3ccccc3N=C(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K10 compound treatment 689689.0 230000.0 0.47 737966.0 262000.0 0.57 0.7369 0.996 1980661 ChemDiv1_023462 COc1ccc(C=c2sc3nc(nn3c2=O)c4ccc(Cl)cc4)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K11 compound treatment 765429.0 305000.0 0.63 762972.0 287000.0 0.62 0.8857 1.0 1980662 ChemDiv1_023463 Clc1nc(cc(n1)c2cnc(nc2N3CCCCC3)N4CCCCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K12 compound treatment 711645.0 252000.0 0.52 709098.0 234000.0 0.51 0.7248 0.9999 1980663 ChemDiv1_023464 COc1ccc(/N=C/2\NC(C)(C)Cc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K13 compound treatment 706440.0 246000.0 0.51 705016.0 230000.0 0.5 0.7109 0.9999 1276595 ChemDiv1_023465 Cc1cccc(c1C)n2sc3c(-c4ccccc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K14 compound treatment 736980.0 277000.0 0.57 825606.0 350000.0 0.76 0.9401 0.9903 1951931 ChemDiv1_023466 CC(=O)OCC1(C2C(C(=O)N(C2=O)c3ccccc3)C4(COC(=O)C)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K15 compound treatment 750185.0 290000.0 0.6 782960.0 307000.0 0.67 0.8941 0.9986 1980664 ChemDiv1_023467 Fc1ccc(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K16 compound treatment 708905.0 249000.0 0.51 683621.0 208000.0 0.45 0.6818 0.9979 1123035 ChemDiv1_023468 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K17 compound treatment 750786.0 291000.0 0.6 735749.0 260000.0 0.56 0.8227 0.9995 1940558 ChemDiv1_023469 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(OC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K18 compound treatment 697187.0 237000.0 0.49 668010.0 193000.0 0.42 0.6408 0.9968 1980665 ChemDiv1_023470 COc1cccc(c1)C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K19 compound treatment 720399.0 260000.0 0.54 727639.0 252000.0 0.55 0.7659 1.0 1980666 ChemDiv1_023471 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3cccc(c3)[N+](=O)[O-])/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K20 compound treatment 627756.0 168000.0 0.35 688779.0 213000.0 0.46 0.5712 0.9899 1279417 ChemDiv1_023472 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4F)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K21 compound treatment 770673.0 311000.0 0.64 726647.0 251000.0 0.54 0.8378 0.9966 1948107 ChemDiv1_023473 CCOC(=O)C1=C(Nc2cccc3ccccc23)S/C(=C\c4ccc(cc4)[N+](=O)[O-])/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K22 compound treatment 690479.0 230000.0 0.48 654053.0 179000.0 0.39 0.6096 0.9947 1265632 ChemDiv1_023474 COc1cc(ccc1O)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K23 mock treatment 695635.0 236000.0 0.49 705021.0 230000.0 0.5 0.6952 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 K24 mock treatment 222763.0 -237000.0 -0.49 217014.0 -258000.0 -0.56 -0.742 -0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L01 compound treatment 694673.0 235000.0 0.48 610869.0 135000.0 0.29 0.5497 0.971 1370330 ChemDiv1_023475 C1CCC(CC1)Nc2ncnc3c4ccccc4oc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L02 compound treatment 666364.0 206000.0 0.43 662981.0 187000.0 0.41 0.5881 0.9997 1132951 ChemDiv1_023476 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L03 compound treatment 700451.0 240000.0 0.5 738700.0 263000.0 0.57 0.7537 0.9976 1674056 ChemDiv1_023477 CC(C)OC(=O)c1nnn(c1CN2CCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L04 compound treatment 690404.0 230000.0 0.48 668857.0 193000.0 0.42 0.6322 0.998 1600822 ChemDiv1_023478 Fc1ccc(C2OC3(C4C2C(=O)N(C4=O)c5ccc(Cl)cc5)C(=O)c6ccccc6C3=O)c(F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L05 compound treatment 708947.0 249000.0 0.51 705443.0 230000.0 0.5 0.7152 0.9999 1980667 ChemDiv1_023479 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L06 compound treatment 694714.0 235000.0 0.48 671235.0 196000.0 0.42 0.6421 0.9978 1523691 ChemDiv1_023480 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccccc3)c4cccc(O)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L07 compound treatment 720818.0 261000.0 0.54 718543.0 243000.0 0.53 0.7526 0.9999 1926496 ChemDiv1_023481 Cc1ccc(cc1)C2OC(=O)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L08 compound treatment 718843.0 259000.0 0.53 677435.0 202000.0 0.44 0.6868 0.995 1444633 ChemDiv1_023482 COc1ccccc1NC(=O)C2C3CC(C)(NC2=O)Oc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L09 compound treatment 701878.0 242000.0 0.5 704085.0 229000.0 0.49 0.7028 1.0 1172587 ChemDiv1_023483 CCC(C)(C)C1CCc2oc3ccc(NS(=O)(=O)c4ccc(C)cc4)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L10 compound treatment 760147.0 300000.0 0.62 784111.0 309000.0 0.67 0.9104 0.9993 1389112 ChemDiv1_023484 CC1(C)Cc2c(CO1)c(nc3sc4c(ncnc4c23)N5CCCCC5)N6CCOCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L11 compound treatment 849412.0 389000.0 0.8 724548.0 249000.0 0.54 0.9495 0.9811 1710443 ChemDiv1_023485 Cn1c(=O)n(C)c2ncn(Cc3cccc(Br)c3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L12 compound treatment 690300.0 230000.0 0.48 718586.0 243000.0 0.53 0.7081 0.9987 1527801 ChemDiv1_023486 CCC1(C)CC(CC(=O)O)(CCO1)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L13 compound treatment 682467.0 222000.0 0.46 680157.0 205000.0 0.44 0.6379 0.9998 1706417 ChemDiv1_023487 CC(C)c1ccc2n3CCN(CCC#N)C4CCCc(c43)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L14 compound treatment 679712.0 220000.0 0.45 694823.0 219000.0 0.47 0.6563 0.9997 1933214 ChemDiv1_023488 CCC1(C)CC(CCNCc2ccccc2)(CCO1)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L15 compound treatment 822055.0 362000.0 0.75 826865.0 351000.0 0.76 1.0662 1.0 1980668 ChemDiv1_023489 [O-][N+](=O)c1ccc(/C=C(\NC(=O)c2ccco2)/C(=O)NCC=C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L16 compound treatment 758225.0 298000.0 0.62 734775.0 259000.0 0.56 0.8321 0.9989 1980669 ChemDiv1_023490 COc1ccc(cc1)C2OCC3(COC(=O)Nc4ccccc4)C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L17 compound treatment 738096.0 278000.0 0.57 683582.0 208000.0 0.45 0.7243 0.9928 1261026 ChemDiv1_023491 Cc1cc(=O)oc2c3CN(COc3ccc12)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L18 compound treatment 715602.0 256000.0 0.53 713623.0 238000.0 0.52 0.7375 0.9999 1702761 ChemDiv1_023492 COc1ccc(cc1)C2OCC3(CO)C(C)C=C(C)C2C3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L19 compound treatment 706900.0 247000.0 0.51 623377.0 148000.0 0.32 0.5866 0.9749 1228670 ChemDiv1_023493 CCOC(=O)c1cnc2ccccc2c1Nc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L20 compound treatment 724901.0 265000.0 0.55 718960.0 243000.0 0.53 0.7592 0.9998 1980670 ChemDiv1_023494 CSc1nnc2c3ccccc3n(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L21 compound treatment 742114.0 282000.0 0.58 692093.0 217000.0 0.47 0.7432 0.9942 1326574 ChemDiv1_023495 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L22 compound treatment 723754.0 264000.0 0.54 710000.0 234000.0 0.51 0.7438 0.9994 1485387 ChemDiv1_023496 CCCc1nc2CC(C)(C)CC(=O)c2c3c4cc(Br)ccc4[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L23 mock treatment 696764.0 237000.0 0.49 690182.0 215000.0 0.46 0.6741 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 L24 mock treatment 235288.0 -225000.0 -0.46 305039.0 -170000.0 -0.37 -0.589 -0.9936 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M01 compound treatment 615712.0 156000.0 0.32 598637.0 123000.0 0.27 0.4157 0.9957 1783794 ChemDiv1_023497 CN(C)c1ccc(cc1)C2N3CC4(CN2CC(C3)([N+](=O)[O-])C4(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M02 compound treatment 1292478.0 832000.0 1.72 1689694.0 1210000.0 2.63 3.0734 0.9788 1980671 ChemDiv1_023498 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(O)c(OCC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M03 compound treatment 622307.0 162000.0 0.33 705629.0 230000.0 0.5 0.5891 0.9814 1980672 ChemDiv1_023499 Cn1c2ccccc2c3n(c4ccc(cc4)[N+](=O)[O-])c(=O)c(C#N)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M04 compound treatment 666461.0 206000.0 0.43 671781.0 196000.0 0.42 0.6017 1.0 1980673 ChemDiv1_023500 Cc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5ccccc5C(F)(F)F)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M05 compound treatment 716213.0 256000.0 0.53 694044.0 219000.0 0.47 0.7084 0.9985 1119534 ChemDiv1_023501 O=C(Cn1cnc2c(C#N)c3CCCCn3c2c1=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M06 compound treatment 655857.0 196000.0 0.4 664693.0 189000.0 0.41 0.5754 1.0 1925881 ChemDiv1_023502 COc1ccc2N(C(=O)CSc3nc(C)cc(C)n3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M07 compound treatment 708968.0 249000.0 0.51 717998.0 242000.0 0.52 0.7345 0.9999 1851989 ChemDiv1_023503 Cc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4cccc(c4)[N+](=O)[O-])C(=O)CCC3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M08 compound treatment 593031.0 133000.0 0.27 613439.0 138000.0 0.3 0.4052 0.9991 1356242 ChemDiv1_023504 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M09 compound treatment 732038.0 272000.0 0.56 690054.0 215000.0 0.46 0.7254 0.9956 1980674 ChemDiv1_023505 COc1ccc(C2=Nc3ccccc3N=C(C2)c4ccccc4)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M10 compound treatment 689246.0 229000.0 0.47 723022.0 248000.0 0.54 0.7134 0.9981 1980675 ChemDiv1_023506 Clc1ccc(cc1)c2nc3sc(=Cc4ccco4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M11 compound treatment 659433.0 199000.0 0.41 686134.0 211000.0 0.46 0.6134 0.9987 1980676 ChemDiv1_023507 O=C1C2=C(Nc3ccccc3SC2c4ccc(OCc5ccccc5)cc4)c6ccccc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M12 compound treatment 702511.0 242000.0 0.5 701536.0 226000.0 0.49 0.6999 0.9999 1980677 ChemDiv1_023508 COc1ccc(/N=C/2\NC(C)(C)Cc3cc(OC)c(OC)cc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M13 compound treatment 681266.0 221000.0 0.46 706295.0 231000.0 0.5 0.6761 0.999 1338168 ChemDiv1_023509 Cc1c(Cl)cccc1n2sc3c(-c4ccccc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M14 compound treatment 662967.0 203000.0 0.42 698520.0 223000.0 0.48 0.6375 0.9975 1980678 ChemDiv1_023510 NC1=NNC2(O)C(=O)c3ccccc3C2(O)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M15 compound treatment 730287.0 270000.0 0.56 710675.0 235000.0 0.51 0.7544 0.999 1951172 ChemDiv1_023511 Cc1cccc(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M16 compound treatment 679348.0 219000.0 0.45 653309.0 178000.0 0.38 0.5922 0.9967 1222044 ChemDiv1_023512 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(F)c3)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M17 compound treatment 4470810.0 4010000.0 8.28 1711233.0 1240000.0 2.67 7.7457 0.8902 1980679 ChemDiv1_023513 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M18 compound treatment 719867.0 260000.0 0.54 665582.0 190000.0 0.41 0.6702 0.9914 1980680 ChemDiv1_023514 COc1ccc(OC)c(c1)C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M19 compound treatment 731888.0 272000.0 0.56 679080.0 204000.0 0.44 0.7084 0.9928 1948121 ChemDiv1_023515 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(Cl)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M20 compound treatment 683399.0 223000.0 0.46 657909.0 182000.0 0.39 0.6052 0.997 1275578 ChemDiv1_023516 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccc(F)cc4)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M21 compound treatment 661250.0 201000.0 0.42 723179.0 248000.0 0.54 0.6728 0.992 1923918 ChemDiv1_023517 CCOC(=O)C1=C(Nc2cccc3ccccc23)S/C(=C\c4ccccc4)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M22 compound treatment 690305.0 230000.0 0.48 687360.0 212000.0 0.46 0.6603 0.9998 1234358 ChemDiv1_023518 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M23 mock treatment 679620.0 220000.0 0.45 703910.0 228000.0 0.49 0.6701 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 M24 mock treatment 354905.0 -105000.0 -0.22 359764.0 -116000.0 -0.25 -0.3306 -0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N01 compound treatment 676898.0 217000.0 0.45 595787.0 120000.0 0.26 0.5006 0.9667 1736582 ChemDiv1_023519 CCOC(=O)c1nnn(c1CN2CCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N02 compound treatment 748214.0 288000.0 0.59 710795.0 235000.0 0.51 0.7807 0.997 1147786 ChemDiv1_023520 CCOC(=O)c1cc(sc1NC(=O)c2ccc(Br)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N03 compound treatment 708411.0 248000.0 0.51 674486.0 199000.0 0.43 0.6671 0.9962 1541141 ChemDiv1_023521 CC(C)OC(=O)c1nnn(c1CN2CCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N04 compound treatment 660060.0 200000.0 0.41 655790.0 180000.0 0.39 0.5679 0.9996 1980681 ChemDiv1_023522 Clc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5cccc6ccccc56)C(=O)c7ccccc7C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N05 compound treatment 715146.0 255000.0 0.53 686588.0 211000.0 0.46 0.6954 0.9975 1948140 ChemDiv1_023523 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3cc(OC)c(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N06 compound treatment 684732.0 225000.0 0.46 672822.0 197000.0 0.43 0.63 0.9992 1980682 ChemDiv1_023524 Cc1cc(ccc1Cl)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N07 compound treatment 705470.0 245000.0 0.51 709948.0 234000.0 0.51 0.7171 1.0 1980683 ChemDiv1_023525 Cc1ccc(cc1F)C2OC(=O)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N08 compound treatment 654745.0 195000.0 0.4 685588.0 210000.0 0.45 0.6057 0.9981 1536157 ChemDiv1_023526 Cc1ccc(C)c(NC(=O)C2C3CC(C)(NC2=O)Oc4ccccc34)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N09 compound treatment 718944.0 259000.0 0.53 714214.0 239000.0 0.52 0.7432 0.9999 1219111 ChemDiv1_023527 Brc1ccc(cc1)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N10 compound treatment 728771.0 269000.0 0.55 700045.0 225000.0 0.49 0.7359 0.9978 1980684 ChemDiv1_023528 C1CCN(C1)c2ncnc3c2sc4nc(N5CCOCC5)c6CCCCc6c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N11 compound treatment 775312.0 315000.0 0.65 778180.0 303000.0 0.66 0.9234 1.0 1615825 ChemDiv1_023529 N#CCCN1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N12 compound treatment 701444.0 241000.0 0.5 679788.0 204000.0 0.44 0.665 0.9982 1980685 ChemDiv1_023530 CCC1(C)CC(CCNCc2ccc(OC)cc2)(CCO1)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N13 compound treatment 1194080.0 734000.0 1.52 1206832.0 731000.0 1.58 2.1907 0.9998 1980686 ChemDiv1_023531 Cc1ccc2n3CCN(CC(=O)c4ccc(Br)cc4)C5CCCc(c53)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N14 compound treatment 610308.0 150000.0 0.31 697087.0 222000.0 0.48 0.5585 0.9778 1980687 ChemDiv1_023532 CC(=C)CSc1nnc2n(c3ccccc3C)c(=O)c4c5CCCc5sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N15 compound treatment 720985.0 261000.0 0.54 748376.0 273000.0 0.59 0.7985 0.9989 1980688 ChemDiv1_023533 CCN(CC)C(=O)/C(=C/c1ccc(cc1)[N+](=O)[O-])/NC(=O)c2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N16 compound treatment 661399.0 201000.0 0.42 671459.0 196000.0 0.42 0.5938 0.9999 1418816 ChemDiv1_023534 CC1C=C(C)C2C(C)C1(COC(=O)C)COC2c3ccc(cc3)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N17 compound treatment 742337.0 282000.0 0.58 684601.0 209000.0 0.45 0.7321 0.9922 1438450 ChemDiv1_023535 Cc1cc(=O)oc2c3CN(COc3ccc12)c4cccc(Cl)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N18 compound treatment 962086.0 502000.0 1.04 882816.0 407000.0 0.88 1.3562 0.9968 1291079 ChemDiv1_023536 CC1C=C(C)C2C(C)C1(CO)COC2c3ccc(cc3)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N19 compound treatment 719561.0 260000.0 0.54 665794.0 190000.0 0.41 0.67 0.9916 1706459 ChemDiv1_023537 CCOC(=O)c1cnc2ccccc2c1Nc3ccc(C)c(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N20 compound treatment 730973.0 271000.0 0.56 706471.0 231000.0 0.5 0.749 0.9984 1980689 ChemDiv1_023538 CCSc1nnc2c3ccccc3n(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N21 compound treatment 740867.0 281000.0 0.58 687493.0 212000.0 0.46 0.7344 0.9933 1743406 ChemDiv1_023539 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N22 compound treatment 658286.0 198000.0 0.41 718548.0 243000.0 0.53 0.6613 0.9923 1852179 ChemDiv1_023540 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cc(ccc4C)[N+](=O)[O-])C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N23 mock treatment 692829.0 233000.0 0.48 678216.0 203000.0 0.44 0.65 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 N24 mock treatment 201244.0 -259000.0 -0.53 417317.0 -58200.0 -0.13 -0.4668 -0.8505 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O01 compound treatment 636114.0 176000.0 0.36 585515.0 110000.0 0.24 0.4254 0.979 1980690 ChemDiv1_023541 CC1(C)C2(CN3CC1(CN(C2)C3c4ccc(O)cc4)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O02 compound treatment 1405615.0 946000.0 1.95 1400820.0 925000.0 2.0 2.7964 0.9999 1950710 ChemDiv1_023542 CCOC(=O)C1=C(Nc2ccc(F)cc2)S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O03 compound treatment 731899.0 272000.0 0.56 649492.0 174000.0 0.38 0.6631 0.9812 1980691 ChemDiv1_023543 NC(=O)c1cc2[nH]c3ccccc3c2[n+](c1N)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O04 compound treatment 683104.0 223000.0 0.46 663925.0 188000.0 0.41 0.614 0.9982 1117880 ChemDiv1_023544 CC(C)c1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5ccc(F)cc5)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O05 compound treatment 632769.0 173000.0 0.36 648597.0 173000.0 0.37 0.517 0.9997 1171729 ChemDiv1_023545 Clc1ccccc1Cn2cnc3c(C#N)c4CCCCn4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O06 compound treatment 656495.0 196000.0 0.41 647583.0 172000.0 0.37 0.5501 0.9991 1980692 ChemDiv1_023546 COc1cc(ccc1N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O07 compound treatment 669201.0 209000.0 0.43 674802.0 199000.0 0.43 0.6103 1.0 1417601 ChemDiv1_023547 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O08 compound treatment 597662.0 138000.0 0.28 601716.0 126000.0 0.27 0.394 0.9998 1142952 ChemDiv1_023548 COc1cc(ccc1O)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O09 compound treatment 658062.0 198000.0 0.41 663446.0 188000.0 0.41 0.5767 1.0 1590925 ChemDiv1_023549 CC(C)OC(=O)C1=C(C)NC(=O)CC1c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O10 compound treatment 675492.0 215000.0 0.44 709103.0 234000.0 0.51 0.672 0.998 1980693 ChemDiv1_023550 CCCOC(=O)CCCCC1SCC(NC(=O)c2ccccc2)C1NC(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O11 compound treatment 645539.0 185000.0 0.38 655007.0 180000.0 0.39 0.5455 1.0 1924576 ChemDiv1_023551 COc1ccc(OC)c(c1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O12 compound treatment 659019.0 199000.0 0.41 680800.0 205000.0 0.44 0.6046 0.9992 1980694 ChemDiv1_023552 O=C(Nc1ccc2-c3ccc(NC(=O)C4(CC5CC6CC(C5)C4)C6)cc3S(=O)(=O)c2c1)C7(CC8CC9CC(C8)C7)C9 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O13 compound treatment 689025.0 229000.0 0.47 677511.0 202000.0 0.44 0.6434 0.9992 1980695 ChemDiv1_023553 CCOc1ccc2N(C(=O)C(C)CC)C(C)(C)C(=S)/C(=C/3\SC(=C(S3)c4ccccc4)C(=O)C)/c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O14 compound treatment 694478.0 234000.0 0.48 673028.0 198000.0 0.43 0.6445 0.9981 1410531 ChemDiv1_023554 O=C1N(C(C2=C1NCCN=C2c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O15 compound treatment 692475.0 232000.0 0.48 695058.0 220000.0 0.48 0.6753 1.0 1670109 ChemDiv1_023555 Cc1c(O)ccc2c3CCCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O16 compound treatment 670754.0 211000.0 0.43 615041.0 140000.0 0.3 0.5211 0.9841 1980696 ChemDiv1_023556 COc1ccccc1C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O17 compound treatment 689570.0 230000.0 0.47 709703.0 234000.0 0.51 0.6935 0.9994 1980697 ChemDiv1_023557 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(Cl)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O18 compound treatment 673385.0 213000.0 0.44 588796.0 113000.0 0.25 0.4848 0.9618 1682646 ChemDiv1_023558 COCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O19 compound treatment 695134.0 235000.0 0.49 662871.0 187000.0 0.41 0.6299 0.996 1948169 ChemDiv1_023559 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3cc(OC)c(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O20 compound treatment 677061.0 217000.0 0.45 612353.0 137000.0 0.3 0.5262 0.9798 1980698 ChemDiv1_023560 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccc(cc4)[N+](=O)[O-])c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O21 compound treatment 713465.0 253000.0 0.52 695579.0 220000.0 0.48 0.7067 0.9989 1946101 ChemDiv1_023561 CCOC(=O)C1=C(Nc2cccc3ccccc23)S/C(=C\c4ccc(Cl)cc4)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O22 compound treatment 666120.0 206000.0 0.43 646339.0 171000.0 0.37 0.5623 0.9976 1338595 ChemDiv1_023562 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(C)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O23 mock treatment 676258.0 216000.0 0.45 658880.0 183000.0 0.4 0.5963 0.9983 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 O24 mock treatment 155818.0 -304000.0 -0.63 418688.0 -56800.0 -0.12 -0.531 -0.8298 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P01 compound treatment 627883.0 168000.0 0.35 577913.0 102000.0 0.22 0.4017 0.9767 1381888 ChemDiv1_023563 CCOC(=O)c1nnn(c1CN2CCN(C)CC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P02 compound treatment 678373.0 218000.0 0.45 600618.0 125000.0 0.27 0.5102 0.9703 1205334 ChemDiv1_023564 CCOC(=O)c1cc(sc1NC(=O)c2ccc(C)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P03 compound treatment 653689.0 194000.0 0.4 618083.0 143000.0 0.31 0.5009 0.9918 1328378 ChemDiv1_023565 CC(C)OC(=O)c1nnn(c1CN2CCCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P04 compound treatment 675440.0 215000.0 0.44 597454.0 122000.0 0.26 0.5011 0.969 1980699 ChemDiv1_023566 Cc1cccc(c1)C2OC3(C4C2C(=O)N(C4=O)c5cccc6ccccc56)C(=O)c7ccccc7C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P05 compound treatment 663870.0 204000.0 0.42 589232.0 114000.0 0.25 0.4716 0.9674 1932116 ChemDiv1_023567 CCOC(=O)C1=C(Nc2ccc(cc2)[N+](=O)[O-])S/C(=C\c3ccc(O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P06 compound treatment 670093.0 210000.0 0.43 607867.0 132000.0 0.29 0.5092 0.9798 1527893 ChemDiv1_023568 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P07 compound treatment 661423.0 201000.0 0.42 639300.0 164000.0 0.35 0.5446 0.9969 1980700 ChemDiv1_023569 Clc1ccc(cc1)C2OC(=O)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P08 compound treatment 667124.0 207000.0 0.43 619793.0 144000.0 0.31 0.5231 0.9881 1980701 ChemDiv1_023570 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P09 compound treatment 664011.0 204000.0 0.42 622681.0 147000.0 0.32 0.523 0.9905 1864631 ChemDiv1_023571 CCC(C)(C)C1CCc2oc3c(cc(NS(=O)(=O)c4ccccc4)c5ccccc35)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P10 compound treatment 658911.0 199000.0 0.41 652377.0 177000.0 0.38 0.561 0.9994 1980702 ChemDiv1_023572 CCCCN(CCCC)c1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P11 compound treatment 667276.0 207000.0 0.43 636231.0 161000.0 0.35 0.5485 0.9947 1209889 ChemDiv1_023573 CC(=O)N1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P12 compound treatment 690094.0 230000.0 0.47 638265.0 163000.0 0.35 0.5849 0.9892 1933081 ChemDiv1_023574 CCC1(C)CC(CCNCc2ccc(F)cc2)(CCO1)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P13 compound treatment 658188.0 198000.0 0.41 634162.0 159000.0 0.34 0.532 0.9962 1980703 ChemDiv1_023575 [O-][N+](=O)c1ccc(cc1N2CCCCC2)N3CCN(CC3)C(=O)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P14 compound treatment 665303.0 205000.0 0.42 652470.0 177000.0 0.38 0.5705 0.9987 1980704 ChemDiv1_023576 Cc1ccccc1n2c(=O)c3c4CCCCc4sc3n5c(SCC=C)nnc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P15 compound treatment 663783.0 204000.0 0.42 604373.0 129000.0 0.28 0.4946 0.9801 1980705 ChemDiv1_023577 CCOC(=O)c1ccc(NC(=O)/C(=C\c2ccc3OCOc3c2)/NC(=O)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P16 compound treatment 703079.0 243000.0 0.5 656277.0 181000.0 0.39 0.6314 0.9924 1980706 ChemDiv1_023578 CC1C=C(C)C2C(C)C1(COC(=O)NC3CCCCC3)COC2c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P17 compound treatment 691681.0 232000.0 0.48 664194.0 189000.0 0.41 0.6269 0.9969 1354276 ChemDiv1_023579 CCc1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P18 compound treatment 691800.0 232000.0 0.48 679147.0 204000.0 0.44 0.65 0.9992 1204835 ChemDiv1_023580 CC1C=C(C)C2C(C)C1(CO)COC2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P19 compound treatment 704614.0 245000.0 0.5 614434.0 139000.0 0.3 0.5696 0.9694 1408422 ChemDiv1_023581 CCOC(=O)c1cnc2ccccc2c1Nc3ccccc3CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P20 compound treatment 678770.0 219000.0 0.45 659226.0 184000.0 0.4 0.6005 0.998 1521888 ChemDiv1_023582 OC12N(C(=S)N(c3ccccc3)C2(O)c4ccccc4C1=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P21 compound treatment 684484.0 224000.0 0.46 621658.0 146000.0 0.32 0.5513 0.9827 1119796 ChemDiv1_023583 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Nc4ccc(C)c(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P22 compound treatment 665486.0 205000.0 0.42 638352.0 163000.0 0.35 0.5491 0.9958 1980707 ChemDiv1_023584 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4cc(OC)c(OC)c(OC)c4)C(=O)CCC3)c5cc(ccc5C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P23 mock treatment 643662.0 184000.0 0.38 603145.0 128000.0 0.28 0.4634 0.9879 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.653 P24 mock treatment 191390.0 -269000.0 -0.55 488703.0 13200.0 0.03 -0.3719 -0.6698 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A01 compound treatment 619746.0 161000.0 0.33 596483.0 135000.0 0.29 0.441 0.998 1980708 ChemDiv1_023585 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CCC3)c6cc(ccc6C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A02 compound treatment 633476.0 174000.0 0.36 691374.0 230000.0 0.5 0.6062 0.9875 1980709 ChemDiv1_023586 [O-][N+](=O)c1ccc(Cl)c(c1)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3cc(ccc3Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A03 compound treatment 676808.0 218000.0 0.45 620016.0 158000.0 0.34 0.5603 0.991 1533436 ChemDiv1_023587 COc1ccc(OC)c(c1)N2C(=C(C(C3=C2CCCC3=O)c4ccc5OCOc5c4)C(=O)c6ccccc6)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A04 compound treatment 677964.0 219000.0 0.45 634579.0 173000.0 0.37 0.5843 0.9956 1980710 ChemDiv1_023588 COC(=O)c1ccccc1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A05 compound treatment 707491.0 248000.0 0.51 655888.0 194000.0 0.42 0.66 0.9951 1852303 ChemDiv1_023589 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CCC3)c6cccc(Br)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A06 compound treatment 693580.0 235000.0 0.48 657188.0 196000.0 0.42 0.6417 0.9978 1980711 ChemDiv1_023590 CC(=O)N[C@H]1[C@H](Oc2cccc3ccccc23)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A07 compound treatment 699021.0 240000.0 0.5 663737.0 202000.0 0.44 0.6596 0.9981 1543945 ChemDiv1_023591 OCC1OC(C(O)C1O)n2cnc3c(=O)[nH]cnc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A08 compound treatment 720931.0 262000.0 0.54 671463.0 210000.0 0.45 0.7034 0.9962 1980712 ChemDiv1_023592 FC(F)(F)c1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A09 compound treatment 708629.0 250000.0 0.52 660241.0 199000.0 0.43 0.6683 0.9959 1514188 ChemDiv1_023593 CCN1C(=O)CC(=Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A10 compound treatment 713327.0 254000.0 0.52 667359.0 206000.0 0.45 0.686 0.9966 1980713 ChemDiv1_023594 CCCCN(CCCC)CC(O)CN(c1cccc2ccccc12)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A11 compound treatment 724194.0 265000.0 0.55 661813.0 200000.0 0.43 0.6934 0.9933 1947154 ChemDiv1_023595 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4ccc(F)cc4F)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A12 compound treatment 694288.0 235000.0 0.49 638108.0 176000.0 0.38 0.6135 0.9929 1980714 ChemDiv1_023596 COc1ccccc1N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A13 compound treatment 4573977.0 4110000.0 8.49 4906518.0 4440000.0 9.62 12.8092 0.9981 1980715 ChemDiv1_023597 CN1C=C(C(C[N+](=O)[O-])c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A14 compound treatment 719025.0 260000.0 0.54 670288.0 209000.0 0.45 0.6988 0.9963 1980716 ChemDiv1_023598 COc1ccc(cc1)N(CC(O)CN(CC(C)C)CC(C)C)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A15 compound treatment 720625.0 262000.0 0.54 694509.0 233000.0 0.5 0.7382 0.9994 1355535 ChemDiv1_023599 CCC(=O)OC1N=C(c2ccccc2Cl)c3cc(Br)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A16 compound treatment 718468.0 259000.0 0.54 675288.0 214000.0 0.46 0.7057 0.9973 1980717 ChemDiv1_023600 CCCCN(CCCC)CC(O)CN(c1ccc(OC)cc1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A17 compound treatment 729719.0 271000.0 0.56 663606.0 202000.0 0.44 0.7042 0.9926 1593609 ChemDiv1_023601 CC(=O)OC1N=C(c2ccccc2)c3ccccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A18 compound treatment 1245746.0 787000.0 1.62 659988.0 198000.0 0.43 1.4519 0.8643 1238636 ChemDiv1_023602 Cc1cc(CN2CCCCC2)cc(C)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A19 compound treatment 680641.0 222000.0 0.46 650346.0 189000.0 0.41 0.6123 0.9984 1980718 ChemDiv1_023603 CCOC(=O)C1=C(Nc2ccc(Cl)cc2)S/C(=C\c3ccc(OC)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A20 compound treatment 674552.0 216000.0 0.44 633284.0 172000.0 0.37 0.5773 0.996 1419767 ChemDiv1_023604 CCC(=O)Nc1cccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A21 compound treatment 1057678.0 599000.0 1.24 1026571.0 565000.0 1.22 1.7384 1.0 1980719 ChemDiv1_023605 COC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A22 compound treatment 664217.0 205000.0 0.42 598562.0 137000.0 0.3 0.5091 0.9847 1701266 ChemDiv1_023606 CCOc1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A23 mock treatment 600667.0 142000.0 0.29 606587.0 145000.0 0.31 0.4286 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 A24 mock treatment 226188.0 -233000.0 -0.48 227141.0 -235000.0 -0.51 -0.6988 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B01 compound treatment 664208.0 205000.0 0.42 598462.0 137000.0 0.3 0.5089 0.9847 1980720 ChemDiv1_023607 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3cccc(OC)c3)c4ccc(OC)cc24)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B02 compound treatment 669159.0 210000.0 0.43 622379.0 161000.0 0.35 0.5527 0.994 1980721 ChemDiv1_023608 O=C1C2C(C3=C(CCCC3=O)N=C2c4ccccc14)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B03 compound treatment 669247.0 210000.0 0.43 657315.0 196000.0 0.42 0.6063 0.9999 1570012 ChemDiv1_023609 O=S(=O)(c1nc(Cc2ccccc2)oc1N3CCCCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B04 compound treatment 691181.0 232000.0 0.48 677117.0 215000.0 0.47 0.6687 0.9999 1650679 ChemDiv1_023610 Cc1ccc2N(C(=O)CN3C(=O)CCC3=O)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B05 compound treatment 728529.0 270000.0 0.56 705063.0 243000.0 0.53 0.7659 0.9996 1980722 ChemDiv1_023611 Clc1ccccc1NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B06 compound treatment 715008.0 256000.0 0.53 676178.0 215000.0 0.46 0.702 0.9979 1980723 ChemDiv1_023612 Cc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)C=C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B07 compound treatment 747796.0 289000.0 0.6 728782.0 267000.0 0.58 0.8304 0.9999 1516503 ChemDiv1_023613 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccc(F)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B08 compound treatment 727305.0 268000.0 0.55 700838.0 239000.0 0.52 0.7577 0.9994 1980724 ChemDiv1_023614 Cc1cccc(c1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B09 compound treatment 759873.0 301000.0 0.62 725598.0 264000.0 0.57 0.8431 0.9991 1786529 ChemDiv1_023615 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccccc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B10 compound treatment 741647.0 283000.0 0.58 686729.0 225000.0 0.49 0.757 0.996 1702560 ChemDiv1_023616 CCOc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4cccc(F)c4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B11 compound treatment 769364.0 310000.0 0.64 731649.0 270000.0 0.58 0.8662 0.9989 1980725 ChemDiv1_023617 CC(C)(C)C1CCc2c(C1)sc3c2c(=O)n(c4ccccc4)c5nnc(SCc6ccc(Cl)c(Cl)c6)n53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B12 compound treatment 656036.0 197000.0 0.41 599734.0 138000.0 0.3 0.4989 0.9885 1942908 ChemDiv1_023618 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4cccs4)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B13 compound treatment 737836.0 279000.0 0.58 758689.0 297000.0 0.64 0.8616 0.9985 1554408 ChemDiv1_023619 CNC(=O)N1c2ccccc2C=Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B14 compound treatment 749753.0 291000.0 0.6 709431.0 248000.0 0.54 0.8036 0.9984 1943373 ChemDiv1_023620 CC1(C)N(C(=O)CN2CCOCC2)c3ccccc3-c4c1ssc4=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B15 compound treatment 784174.0 325000.0 0.67 750010.0 288000.0 0.62 0.916 0.9993 1980726 ChemDiv1_023621 COc1ccc(/C=C/C(=O)NCC2(CCOCC2)c3ccc(OC)c(OC)c3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B16 compound treatment 737481.0 278000.0 0.57 712359.0 251000.0 0.54 0.7902 0.9996 1872666 ChemDiv1_023622 Cc1cc2NC(C)(C)c3ssc(=Nc4ccc(Cl)cc4)c3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B17 compound treatment 787084.0 328000.0 0.68 701740.0 240000.0 0.52 0.8463 0.9914 1980727 ChemDiv1_023623 CC(C)C(=O)N1c2cc(C)c(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B18 compound treatment 710455.0 251000.0 0.52 685973.0 224000.0 0.49 0.7103 0.9994 1263506 ChemDiv1_023624 CC1CC(C)(C)N(C(=O)Nc2cccc(Cl)c2)c3ccc(C)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B19 compound treatment 724264.0 265000.0 0.55 699863.0 238000.0 0.52 0.7518 0.9995 1530498 ChemDiv1_023625 Fc1ccccc1C(=O)N2c3ccccc3CCc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B20 compound treatment 709040.0 250000.0 0.52 697939.0 236000.0 0.51 0.7266 1.0 1980728 ChemDiv1_023626 CCOC(=O)C(=O)N1c2cc(C)ccc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B21 compound treatment 747715.0 289000.0 0.6 700594.0 239000.0 0.52 0.7871 0.9975 1542086 ChemDiv1_023627 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B22 compound treatment 704676.0 246000.0 0.51 663541.0 202000.0 0.44 0.6676 0.9973 1628701 ChemDiv1_023628 CC(C)c1ccc(cc1)n2sc3c(-c4cc(C)c(C)cc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B23 mock treatment 667207.0 208000.0 0.43 641360.0 180000.0 0.39 0.5789 0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 B24 mock treatment 233444.0 -226000.0 -0.47 226020.0 -236000.0 -0.51 -0.6899 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C01 compound treatment 644870.0 186000.0 0.38 633155.0 172000.0 0.37 0.5338 0.9999 1980729 ChemDiv1_023629 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4C)[N+](=O)[O-])C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C02 compound treatment 664601.0 206000.0 0.42 671277.0 210000.0 0.45 0.6209 0.9994 1374908 ChemDiv1_023630 CCOc1ccc(c2ccccc12)S(=O)(=O)N3CCCN(CC3)S(=O)(=O)c4ccc(OCC)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C03 compound treatment 720469.0 261000.0 0.54 722388.0 261000.0 0.56 0.7807 0.9998 1736061 ChemDiv1_023631 COc1ccc(OC)c(c1)N2C(=C(C(C3=C2CCCC3=O)c4ccc5OCOc5c4)C(=O)c6ccc(C)cc6)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C04 compound treatment 702741.0 244000.0 0.5 684863.0 223000.0 0.48 0.6974 0.9998 1980730 ChemDiv1_023632 CC(=O)N[C@H]1[C@H](Oc2ccccc2NC(=O)C)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C05 compound treatment 737048.0 278000.0 0.57 713839.0 252000.0 0.55 0.7918 0.9997 1425717 ChemDiv1_023633 COc1ccc(C)cc1S(=O)(=O)n2nnc3cc(Cl)ccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C06 compound treatment 738689.0 280000.0 0.58 700823.0 239000.0 0.52 0.7743 0.9985 1870719 ChemDiv1_023634 Clc1ccc(C2OC3(C4C2C(=O)N(C5CCCC5)C4=O)C(=O)c6ccccc6C3=O)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C07 compound treatment 732794.0 274000.0 0.57 725681.0 264000.0 0.57 0.8037 1.0 1980731 ChemDiv1_023635 C1C(C=C(N2c3ccccc3NC12c4ccccc4)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C08 compound treatment 719341.0 260000.0 0.54 728343.0 267000.0 0.58 0.7882 0.9994 1980732 ChemDiv1_023636 Nc1ccn(C2CC(O)C(COC(c3ccccc3)(c4ccccc4)c5ccccc5)O2)c(=O)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C09 compound treatment 745641.0 287000.0 0.59 735144.0 274000.0 0.59 0.837 1.0 1603489 ChemDiv1_023637 CC1(C)Cc2nc(Cl)c(C#N)cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C10 compound treatment 684834.0 226000.0 0.47 697812.0 236000.0 0.51 0.6911 0.9989 1980733 ChemDiv1_023638 Cc1ccc(cc1)N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C11 compound treatment 763612.0 305000.0 0.63 763587.0 302000.0 0.65 0.9067 0.9998 1948478 ChemDiv1_023639 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4cccc(F)c4F)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C12 compound treatment 721816.0 263000.0 0.54 695174.0 234000.0 0.51 0.741 0.9994 1980734 ChemDiv1_023640 CCCCN(CCCC)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C13 compound treatment 656277.0 197000.0 0.41 656125.0 194000.0 0.42 0.5856 0.9999 1980735 ChemDiv1_023641 CN1C=C(C(C#N)c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C14 compound treatment 716346.0 257000.0 0.53 684028.0 222000.0 0.48 0.716 0.9988 1980736 ChemDiv1_023642 CC(C)CN(CC(C)C)CC(O)CN(c1cccc2ccccc12)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C15 compound treatment 782794.0 324000.0 0.67 745554.0 284000.0 0.61 0.9071 0.9991 1253541 ChemDiv1_023643 CC(C)C(=O)OC1N=C(c2ccccc2Cl)c3cc(Br)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C16 compound treatment 753700.0 295000.0 0.61 754442.0 293000.0 0.63 0.8783 0.9998 1980737 ChemDiv1_023644 CCc1ccccc1N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C17 compound treatment 768562.0 310000.0 0.64 731200.0 270000.0 0.58 0.8644 0.999 1626587 ChemDiv1_023645 CN1C(=O)C(O)N=C(c2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C18 compound treatment 745237.0 286000.0 0.59 721131.0 259000.0 0.56 0.8149 0.9997 1021065 ChemDiv1_023646 CN(C)Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C19 compound treatment 1292841.0 834000.0 1.72 1191529.0 730000.0 1.58 2.3342 0.9991 1980738 ChemDiv1_023647 CCOC(=O)C1=C(Nc2ccc(Cl)cc2)S/C(=C/c3ccc(cc3)N(C)C)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C20 compound treatment 703602.0 245000.0 0.5 720937.0 259000.0 0.56 0.7538 0.9986 1322931 ChemDiv1_023648 CC1(C)Nc2ccccc2-c3c1ssc3=Nc4cccc(NC(=O)c5ccccc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C21 compound treatment 744170.0 285000.0 0.59 761803.0 300000.0 0.65 0.8756 0.9988 1931486 ChemDiv1_023649 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C\c3ccc(O)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C22 compound treatment 713897.0 255000.0 0.53 712259.0 251000.0 0.54 0.7556 0.9999 1356465 ChemDiv1_023650 CCOc1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(F)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C23 mock treatment 659948.0 201000.0 0.41 680262.0 219000.0 0.47 0.6279 0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 C24 mock treatment 209265.0 -250000.0 -0.52 237246.0 -224000.0 -0.49 -0.708 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D01 compound treatment 655056.0 196000.0 0.4 595865.0 134000.0 0.29 0.4916 0.9868 1980739 ChemDiv1_023651 Cc1ccc2N(C(=O)CN3CCC(CC3)C(=O)N)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D02 compound treatment 627613.0 169000.0 0.35 634939.0 173000.0 0.38 0.5113 0.9993 1980740 ChemDiv1_023652 Cc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D03 compound treatment 715820.0 257000.0 0.53 693097.0 231000.0 0.5 0.7291 0.9996 1980741 ChemDiv1_023653 Brc1ccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D04 compound treatment 644651.0 186000.0 0.38 643095.0 181000.0 0.39 0.5487 0.9999 1980742 ChemDiv1_023654 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)CCC3=O)c4cc(OC)ccc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D05 compound treatment 690049.0 231000.0 0.48 724253.0 263000.0 0.57 0.7391 0.9962 1980743 ChemDiv1_023655 Cc1cccc(C)c1NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D06 compound treatment 663145.0 204000.0 0.42 681232.0 220000.0 0.48 0.634 0.9982 1872620 ChemDiv1_023656 Cc1ccc(N=c2ssc3c2-c4ccc(C)cc4NC3(C)C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D07 compound treatment 731505.0 272000.0 0.56 725429.0 264000.0 0.57 0.8015 1.0 1331333 ChemDiv1_023657 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)N6CCOCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D08 compound treatment 703505.0 244000.0 0.5 692009.0 230000.0 0.5 0.7094 1.0 1980744 ChemDiv1_023658 CC(=O)N1c2c(C)cc(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D09 compound treatment 717032.0 258000.0 0.53 747269.0 286000.0 0.62 0.8138 0.9972 1980745 ChemDiv1_023659 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D10 compound treatment 710325.0 251000.0 0.52 712238.0 251000.0 0.54 0.7503 0.9998 1623215 ChemDiv1_023660 CC1(C)N(C(=O)c2cccs2)c3ccccc3-c4c1ssc4=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D11 compound treatment 764573.0 306000.0 0.63 728486.0 267000.0 0.58 0.8544 0.999 1980746 ChemDiv1_023661 COc1ccc(cc1)n2c(=O)c3c4CC(C)(C)OCc4sc3n5c(SCc6ccccc6)nnc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D12 compound treatment 629192.0 170000.0 0.35 568352.0 107000.0 0.23 0.4117 0.9793 1980747 ChemDiv1_023662 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4cc(Br)ccc4O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D13 compound treatment 741840.0 283000.0 0.58 676591.0 215000.0 0.47 0.7418 0.9937 1316840 ChemDiv1_023663 CNC(=O)N1c2ccccc2CCc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D14 compound treatment 722751.0 264000.0 0.54 679994.0 218000.0 0.47 0.7191 0.9975 1980748 ChemDiv1_023664 COc1ccc2N(C(=O)CN3CCCCC3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D15 compound treatment 791889.0 333000.0 0.69 744134.0 282000.0 0.61 0.9182 0.9983 1980749 ChemDiv1_023665 COc1ccc(cc1OC)C2(CNC(=O)/C=C/c3ccccc3)CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D16 compound treatment 743676.0 285000.0 0.59 701230.0 240000.0 0.52 0.7822 0.9981 1298175 ChemDiv1_023666 Cc1cc2NC(C)(C)c3ssc(=Nc4ccc(F)cc4)c3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D17 compound treatment 748516.0 289000.0 0.6 745174.0 284000.0 0.61 0.8565 0.9999 1486117 ChemDiv1_023667 Cc1ccc(cc1)n2sc3c(-c4cc(Br)ccc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D18 compound treatment 714961.0 256000.0 0.53 687424.0 226000.0 0.49 0.7191 0.9992 1980750 ChemDiv1_023668 Cc1ccc2-c3c(ssc3=Nc4cccc(C)c4C)C(C)(C)Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D19 compound treatment 758391.0 299000.0 0.62 748132.0 286000.0 0.62 0.8754 1.0 1980751 ChemDiv1_023669 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)c4ccccc4Cl)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D20 compound treatment 715156.0 256000.0 0.53 715665.0 254000.0 0.55 0.7626 0.9998 1980752 ChemDiv1_023670 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)COc3ccc(Cl)cc3)c4ccc(OC)cc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D21 compound treatment 690909.0 232000.0 0.48 726636.0 265000.0 0.57 0.744 0.996 1374630 ChemDiv1_023671 Cc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D22 compound treatment 715559.0 257000.0 0.53 719299.0 258000.0 0.56 0.7688 0.9997 1870730 ChemDiv1_023672 CC(C)c1ccc(cc1)n2sc3c(-c4cc(C)ccc4N(C)C3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D23 mock treatment 684945.0 226000.0 0.47 669777.0 208000.0 0.45 0.6483 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 D24 mock treatment 198197.0 -261000.0 -0.54 290442.0 -171000.0 -0.37 -0.6427 -0.9834 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E01 compound treatment 661218.0 202000.0 0.42 627466.0 166000.0 0.36 0.5489 0.9972 1980753 ChemDiv1_023673 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4C)[N+](=O)[O-])C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E02 compound treatment 676287.0 217000.0 0.45 647288.0 186000.0 0.4 0.6013 0.9985 1618563 ChemDiv1_023674 Cc1ccc(c(C)c1)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E03 compound treatment 689482.0 230000.0 0.48 701526.0 240000.0 0.52 0.7035 0.999 1980754 ChemDiv1_023675 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CC(C)(C)C3)c6cc(OC)ccc6OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E04 compound treatment 683476.0 224000.0 0.46 652390.0 191000.0 0.41 0.6196 0.9983 1980755 ChemDiv1_023676 CCOC(=O)c1ccccc1OC2OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C2NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E05 compound treatment 692753.0 234000.0 0.48 675775.0 214000.0 0.46 0.6689 0.9998 1473189 ChemDiv1_023677 COc1cc(C)c(cc1S(=O)(=O)n2nnc3ccccc23)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E06 compound treatment 694453.0 235000.0 0.49 680925.0 219000.0 0.47 0.6793 0.9999 1980756 ChemDiv1_023678 CC(=O)OC[C@H]1O[C@@H](Oc2cccc3ccccc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E07 compound treatment 734731.0 276000.0 0.57 706880.0 245000.0 0.53 0.7778 0.9994 1980757 ChemDiv1_023679 COc1ccc(/C=C/2\CCCC3=C2N4c5ccccc5OC\64C(CCC/C6=C\c7ccc(OC)cc7)C3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E08 compound treatment 717277.0 258000.0 0.53 715332.0 254000.0 0.55 0.7652 0.9999 1980758 ChemDiv1_023680 CC(C)(C)c1cc(CCC(=O)OCCSCCOC(=O)CCc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E09 compound treatment 721902.0 263000.0 0.54 735082.0 273000.0 0.59 0.8022 0.9991 1373311 ChemDiv1_023681 CC1(C)Cc2nc3c(N)n[nH]c3cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E10 compound treatment 697354.0 238000.0 0.49 714225.0 253000.0 0.55 0.7345 0.9986 1980759 ChemDiv1_023682 CCCCN(CCCC)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E11 compound treatment 698935.0 240000.0 0.5 753512.0 292000.0 0.63 0.7969 0.9927 1947290 ChemDiv1_023683 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4ccc(F)cc4)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E12 compound treatment 711654.0 253000.0 0.52 691854.0 230000.0 0.5 0.7211 0.9997 1980760 ChemDiv1_023684 CC(C)CN(CC(C)C)CC(O)CN(c1ccccc1)S(=O)(=O)c2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E13 compound treatment 1034005.0 575000.0 1.19 1113111.0 651000.0 1.41 1.8363 0.9963 1425548 ChemDiv1_023685 CN1C=C(C(c2c[nH]c3ccccc23)c4ccccc14)c5ccc6ccccc6n5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E14 compound treatment 677426.0 218000.0 0.45 629200.0 168000.0 0.36 0.5752 0.9942 1980761 ChemDiv1_023686 CC(C)CN(CC(C)C)CC(O)CN(c1ccccc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E15 compound treatment 772629.0 314000.0 0.65 755163.0 294000.0 0.64 0.907 1.0 1390593 ChemDiv1_023687 Clc1ccccc1C2=NC(OC(=O)c3ccccc3)C(=O)Nc4ccc(Br)cc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E16 compound treatment 743051.0 284000.0 0.59 747234.0 286000.0 0.62 0.8517 0.9997 1215759 ChemDiv1_023688 OC(CN(c1cccc2ccccc12)S(=O)(=O)c3ccccc3)CN4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E17 compound treatment 707290.0 248000.0 0.51 709766.0 248000.0 0.54 0.7421 0.9997 1704198 ChemDiv1_023689 Cc1ccc2NC(=O)C(O)N=C(c3ccccc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E18 compound treatment 712253.0 253000.0 0.52 734334.0 273000.0 0.59 0.787 0.9982 1578261 ChemDiv1_023690 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E19 compound treatment 723266.0 264000.0 0.55 730376.0 269000.0 0.58 0.797 0.9995 1950578 ChemDiv1_023691 CCOC(=O)C1=C(Nc2ccc(Cl)cc2)S/C(=C\c3ccc(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E20 compound treatment 722892.0 264000.0 0.54 718757.0 257000.0 0.56 0.7787 0.9999 1980762 ChemDiv1_023692 CCC(CC)C(=O)N1c2ccc(C)cc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E21 compound treatment 721298.0 262000.0 0.54 746327.0 285000.0 0.62 0.8185 0.9979 1124103 ChemDiv1_023693 COc1cc(ccc1Cl)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E22 compound treatment 599343.0 140000.0 0.29 627752.0 166000.0 0.36 0.459 0.9943 1402692 ChemDiv1_023694 Cn1c2NC3=C(C(c4ccc(O)cc4)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E23 mock treatment 662958.0 204000.0 0.42 677036.0 215000.0 0.47 0.6273 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 E24 mock treatment 223172.0 -236000.0 -0.49 212187.0 -249000.0 -0.54 -0.726 -0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F01 compound treatment 665372.0 206000.0 0.43 602174.0 141000.0 0.3 0.5163 0.9864 1980763 ChemDiv1_023695 COc1ccc2N(C(=O)CN3CCC(CC3)C(=O)N)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F02 compound treatment 657820.0 199000.0 0.41 639211.0 178000.0 0.38 0.5619 0.9995 1938875 ChemDiv1_023696 Clc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F03 compound treatment 649960.0 191000.0 0.39 703433.0 242000.0 0.52 0.6488 0.9902 1980764 ChemDiv1_023697 Fc1ccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F04 compound treatment 679544.0 221000.0 0.46 673122.0 211000.0 0.46 0.6456 1.0 1980765 ChemDiv1_023698 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(cc2)C3C4C(=O)c5ccccc5C4=Nc6c3c(=O)n(C)c(=O)n6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F05 compound treatment 713840.0 255000.0 0.53 661931.0 200000.0 0.43 0.6785 0.9954 1742199 ChemDiv1_023699 CCCCC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F06 compound treatment 699355.0 240000.0 0.5 692833.0 231000.0 0.5 0.7046 1.0 1578877 ChemDiv1_023700 CCOc1ccc(N=c2ssc3c2-c4ccc(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F07 compound treatment 741214.0 282000.0 0.58 702204.0 241000.0 0.52 0.7801 0.9984 1980766 ChemDiv1_023701 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccc(cc6)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F08 compound treatment 700075.0 241000.0 0.5 663035.0 201000.0 0.44 0.6601 0.9978 1657205 ChemDiv1_023702 CC1(C)N(CC(=O)c2ccc(F)cc2)c3ccccc3-c4c1ssc4=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F09 compound treatment 748428.0 289000.0 0.6 701001.0 239000.0 0.52 0.7888 0.9975 1980767 ChemDiv1_023703 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)OCC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F10 compound treatment 705021.0 246000.0 0.51 722930.0 261000.0 0.57 0.759 0.9986 1417927 ChemDiv1_023704 Cc1cc2N(C(=O)c3cccs3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F11 compound treatment 752643.0 294000.0 0.61 758785.0 297000.0 0.64 0.8834 0.9996 1932987 ChemDiv1_023705 CCOC(=O)c1c(NC(=S)NCc2ccccc2)sc3COC(C)(CC)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F12 compound treatment 612442.0 153000.0 0.32 595199.0 134000.0 0.29 0.4283 0.999 1980768 ChemDiv1_023706 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4cc(ccc4O)[N+](=O)[O-])C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F13 compound treatment 711204.0 252000.0 0.52 722675.0 261000.0 0.56 0.7676 0.9992 1216772 ChemDiv1_023707 CC1(C)NCCN2C1SCC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F14 compound treatment 699062.0 240000.0 0.5 657140.0 195000.0 0.42 0.6496 0.9969 1980769 ChemDiv1_023708 Cc1cc(C)c2N(C(=O)CN3CCOCC3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F15 compound treatment 760273.0 301000.0 0.62 723554.0 262000.0 0.57 0.8406 0.9989 1389453 ChemDiv1_023709 CC1(C)N(C(=O)c2ccccc2Cl)c3ccccc3-c4c1ssc4=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F16 compound treatment 729493.0 270000.0 0.56 691934.0 230000.0 0.5 0.7473 0.9984 1610228 ChemDiv1_023710 CCOc1ccc2N(C(=O)c3cccc(OC)c3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F17 compound treatment 772735.0 314000.0 0.65 761209.0 300000.0 0.65 0.9164 1.0 1532745 ChemDiv1_023711 Cc1ccc(cc1Cl)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6cccc(Br)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F18 compound treatment 703489.0 244000.0 0.5 682726.0 221000.0 0.48 0.6952 0.9996 1980770 ChemDiv1_023712 Cc1cccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F19 compound treatment 724128.0 265000.0 0.55 721584.0 260000.0 0.56 0.7848 0.9999 1237914 ChemDiv1_023713 Cc1ccc2-c3c(sn(c4ccc(C)c(Cl)c4)c3=S)C(C)(C)Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F20 compound treatment 723233.0 264000.0 0.55 706223.0 245000.0 0.53 0.76 0.9999 1135725 ChemDiv1_023714 Cc1cc2N(C(=O)c3ccc4OCOc4c3)C(C)(C)c5ssc(=S)c5-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F21 compound treatment 770655.0 312000.0 0.64 733357.0 272000.0 0.59 0.8707 0.999 1656679 ChemDiv1_023715 Cc1ccc(cc1C)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F22 compound treatment 692763.0 234000.0 0.48 703633.0 242000.0 0.52 0.7115 0.9992 1478711 ChemDiv1_023716 Cc1cc(C)c2NC(C)(C)c3sn(c4ccc(Br)cc4)c(=S)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F23 mock treatment 685354.0 226000.0 0.47 683887.0 222000.0 0.48 0.6705 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 F24 mock treatment 234010.0 -225000.0 -0.46 240932.0 -221000.0 -0.48 -0.6662 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G01 compound treatment 657883.0 199000.0 0.41 620810.0 159000.0 0.34 0.5339 0.9962 1980771 ChemDiv1_023717 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4cc(OC)c(OC)c(OC)c4)C(=O)CCC3)c5ccc(cc5C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G02 compound treatment 665362.0 206000.0 0.43 658295.0 197000.0 0.43 0.6022 1.0 1627240 ChemDiv1_023718 COc1ccc(Br)cc1S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3cc(Br)ccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G03 compound treatment 734512.0 275000.0 0.57 719775.0 258000.0 0.56 0.7972 1.0 1980772 ChemDiv1_023719 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CCC3)c6cc(OC)ccc6OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G04 compound treatment 680958.0 222000.0 0.46 695625.0 234000.0 0.51 0.6821 0.9987 1980773 ChemDiv1_023720 COc1ccc(O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G05 compound treatment 694398.0 235000.0 0.49 658691.0 197000.0 0.43 0.6451 0.9979 1144211 ChemDiv1_023721 CCc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(CC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G06 compound treatment 691632.0 233000.0 0.48 693197.0 232000.0 0.5 0.6939 0.9998 1980774 ChemDiv1_023722 CC(=O)OC[C@H]1O[C@@H](Oc2ccc(C)cc2)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G07 compound treatment 691137.0 232000.0 0.48 711031.0 249000.0 0.54 0.7205 0.9982 1255643 ChemDiv1_023723 Cn1c(=O)n(C)c2ncn(Cc3cccc(Cl)c3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G08 compound treatment 701098.0 242000.0 0.5 699497.0 238000.0 0.51 0.7174 0.9999 1347124 ChemDiv1_023724 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN2CCCCC2)c3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G09 compound treatment 731345.0 272000.0 0.56 718742.0 257000.0 0.56 0.791 1.0 1522626 ChemDiv1_023725 CC1(C)Cc2nc(Cl)c(cc2CO1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G10 compound treatment 687733.0 229000.0 0.47 757581.0 296000.0 0.64 0.7868 0.9887 1204226 ChemDiv1_023726 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN2CCCCC2)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G11 compound treatment 704521.0 246000.0 0.51 761689.0 300000.0 0.65 0.8176 0.9925 1730494 ChemDiv1_023727 COc1ccccc1NC(=O)c2c(NC(=O)c3ccncc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G12 compound treatment 628827.0 170000.0 0.35 658228.0 197000.0 0.43 0.5487 0.9954 1980775 ChemDiv1_023728 CC(C)CN(CC(C)C)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G13 compound treatment 947985.0 489000.0 1.01 971070.0 509000.0 1.1 1.4934 0.999 1980776 ChemDiv1_023729 N#CC1C(=CN(Cc2ccccc2)c3ccccc13)c4ccc5ccccc5n4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G14 compound treatment 742885.0 284000.0 0.59 765776.0 304000.0 0.66 0.8798 0.9983 1980777 ChemDiv1_023730 CCc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G15 compound treatment 757195.0 298000.0 0.62 754065.0 292000.0 0.63 0.8828 0.9999 1137619 ChemDiv1_023731 Clc1ccccc1C2=NC(OC(=O)c3cccnc3)C(=O)Nc4ccc(Br)cc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G16 compound treatment 703228.0 244000.0 0.5 678898.0 217000.0 0.47 0.689 0.9994 1620981 ChemDiv1_023732 Cc1ccc(C)c(c1)N2C(=O)C3C(C2=O)C4(CO)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G17 compound treatment 708562.0 250000.0 0.52 707736.0 246000.0 0.53 0.7409 0.9999 1676436 ChemDiv1_023733 OC1N=C(c2ccccc2)c3cc(Br)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G18 compound treatment 715697.0 257000.0 0.53 691900.0 230000.0 0.5 0.7271 0.9995 1252080 ChemDiv1_023734 CC1CC(C)CN(C1)S(=O)(=O)c2ccc-3c(Cc4cc(ccc43)S(=O)(=O)N5CC(C)CC(C)C5)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G19 compound treatment 778393.0 319000.0 0.66 796471.0 335000.0 0.72 0.9786 0.9989 1947996 ChemDiv1_023735 CCOC(=O)C1=C(Nc2ccc(Cl)cc2)S/C(=C\c3ccc(O)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G20 compound treatment 708104.0 249000.0 0.51 697641.0 236000.0 0.51 0.7248 1.0 1980778 ChemDiv1_023736 CCC(CC)C(=O)N1c2ccc(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G21 compound treatment 651580.0 193000.0 0.4 710131.0 248000.0 0.54 0.6614 0.9889 1440660 ChemDiv1_023737 COc1ccc(cc1C)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G22 compound treatment 700405.0 241000.0 0.5 707704.0 246000.0 0.53 0.7289 0.9994 1230957 ChemDiv1_023738 CC(=O)Oc1cccc(c1)C2C3=C(N(C(=O)C)c4c2c(=O)n(C)c(=O)n4C)c5ccccc5C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G23 mock treatment 670479.0 211000.0 0.44 653875.0 192000.0 0.42 0.6029 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 G24 mock treatment 217339.0 -242000.0 -0.5 214606.0 -247000.0 -0.53 -0.7309 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H01 compound treatment 648231.0 189000.0 0.39 590263.0 129000.0 0.28 0.473 0.9862 1688804 ChemDiv1_023739 COc1cc(C2CC(=O)Nc3c2ccc4ccccc34)c(Br)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H02 compound treatment 646483.0 187000.0 0.39 614141.0 152000.0 0.33 0.507 0.9969 1980779 ChemDiv1_023740 Brc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H03 compound treatment 689966.0 231000.0 0.48 674618.0 213000.0 0.46 0.6631 0.9999 1980780 ChemDiv1_023741 O=C(C(Cc1ccccc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O)N7CCOCC7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H04 compound treatment 602942.0 144000.0 0.3 600278.0 139000.0 0.3 0.4223 1.0 1659455 ChemDiv1_023742 CCOC(=O)c1c(C)nc2-c3ccccc3C(=O)c2c1c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H05 compound treatment 709979.0 251000.0 0.52 691929.0 230000.0 0.5 0.7188 0.9998 1504433 ChemDiv1_023743 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H06 compound treatment 653000.0 194000.0 0.4 642924.0 181000.0 0.39 0.5606 0.9999 1872622 ChemDiv1_023744 Cc1ccc2-c3c(ssc3=Nc4ccc(C)c(Cl)c4)C(C)(C)Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H07 compound treatment 721476.0 262000.0 0.54 731544.0 270000.0 0.58 0.7962 0.9993 1980781 ChemDiv1_023745 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6cccc(c6)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H08 compound treatment 650727.0 192000.0 0.4 621362.0 160000.0 0.35 0.5243 0.9977 1980782 ChemDiv1_023746 Cc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)C=C)c3ccccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H09 compound treatment 701536.0 243000.0 0.5 651598.0 190000.0 0.41 0.6447 0.9952 1980783 ChemDiv1_023747 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)OC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H10 compound treatment 712880.0 254000.0 0.52 706450.0 245000.0 0.53 0.7452 1.0 1781949 ChemDiv1_023748 Cc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5cccc(Cl)c5Cl)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H11 compound treatment 741226.0 282000.0 0.58 692317.0 231000.0 0.5 0.765 0.997 1317763 ChemDiv1_023749 CC1(CN2CC3(C)CN(C1)C2c4cccc(Br)c4)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H12 compound treatment 548736.0 89700.0 0.19 664473.0 203000.0 0.44 0.4414 0.9264 1980784 ChemDiv1_023750 CCCC(=O)N1c2ccccc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H13 compound treatment 731760.0 273000.0 0.56 688813.0 227000.0 0.49 0.7458 0.9977 1229221 ChemDiv1_023751 O=c1[nH]c(nc2-c3ccccc3CC4(CCCCC4)c21)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H14 compound treatment 714066.0 255000.0 0.53 653415.0 192000.0 0.42 0.6658 0.9931 1980785 ChemDiv1_023752 O=C(CN1CCOCC1)N2c3ccccc3CCc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H15 compound treatment 723379.0 264000.0 0.55 713085.0 251000.0 0.54 0.7707 1.0 1980786 ChemDiv1_023753 Cc1ccc2N(C(=O)c3ccccc3Cl)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H16 compound treatment 702087.0 243000.0 0.5 669967.0 208000.0 0.45 0.6736 0.9986 1980787 ChemDiv1_023754 CCOC(=O)C(=O)N1c2ccc(C)cc2C(C)(CC1(C)C)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H17 compound treatment 742064.0 283000.0 0.58 730735.0 269000.0 0.58 0.825 1.0 1525634 ChemDiv1_023755 COc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6cccc(Br)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H18 compound treatment 678093.0 219000.0 0.45 678159.0 217000.0 0.47 0.6511 0.9998 1980788 ChemDiv1_023756 CCC(C)C(=O)N1c2cc(C)c(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H19 compound treatment 740918.0 282000.0 0.58 718849.0 257000.0 0.56 0.8051 0.9998 1146710 ChemDiv1_023757 Cc1ccc2-c3c(sn(c4cc(C)cc(C)c4)c3=S)C(C)(C)Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H20 compound treatment 692455.0 233000.0 0.48 659497.0 198000.0 0.43 0.6435 0.9983 1404091 ChemDiv1_023758 COc1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H21 compound treatment 738621.0 280000.0 0.58 712243.0 251000.0 0.54 0.7917 0.9995 1538219 ChemDiv1_023759 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H22 compound treatment 714580.0 256000.0 0.53 674463.0 213000.0 0.46 0.6987 0.9977 1782434 ChemDiv1_023760 CN1c2ccc(C)cc2-c3c(sn(c4ccc(Cl)c(Cl)c4)c3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H23 mock treatment 669832.0 211000.0 0.44 659740.0 198000.0 0.43 0.6109 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 H24 mock treatment 229842.0 -229000.0 -0.47 205904.0 -256000.0 -0.55 -0.7259 -0.9969 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I01 compound treatment 646603.0 188000.0 0.39 613876.0 152000.0 0.33 0.5068 0.9968 1980789 ChemDiv1_023761 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CCC3)c6ccc(cc6C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I02 compound treatment 657005.0 198000.0 0.41 657085.0 195000.0 0.42 0.5881 0.9999 1980790 ChemDiv1_023762 CC(=O)N[C@H]1[C@H](Oc2ccccc2)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I03 compound treatment 673333.0 214000.0 0.44 686529.0 225000.0 0.49 0.657 0.9989 1192540 ChemDiv1_023763 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4Cl)C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I04 compound treatment 625485.0 166000.0 0.34 685374.0 224000.0 0.48 0.5854 0.9859 1980791 ChemDiv1_023764 CCCCNC(=O)c1ccccc1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I05 compound treatment 704239.0 245000.0 0.51 695910.0 234000.0 0.51 0.7165 1.0 1355212 ChemDiv1_023765 Clc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I06 compound treatment 677588.0 219000.0 0.45 694379.0 233000.0 0.5 0.6752 0.9985 1980792 ChemDiv1_023766 CC(=O)OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I07 compound treatment 999348.0 540000.0 1.12 878094.0 416000.0 0.9 1.4261 0.9944 1419031 ChemDiv1_023767 CCN(CC)c1ccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I08 compound treatment 725801.0 267000.0 0.55 712985.0 251000.0 0.54 0.7741 1.0 1980793 ChemDiv1_023768 OC(CN(Cc1ccccc1)Cc2ccccc2)CN(c3cccc4ccccc34)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I09 compound treatment 708483.0 249000.0 0.51 677716.0 216000.0 0.47 0.6948 0.9988 1727347 ChemDiv1_023769 CCc1nc2c3cc4COC(C)(C)Cc4nc3sc2c(=O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I10 compound treatment 682036.0 223000.0 0.46 661155.0 200000.0 0.43 0.6309 0.9995 1928727 ChemDiv1_023770 Cc1cccc(c1)N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I11 compound treatment 736822.0 278000.0 0.57 712758.0 251000.0 0.54 0.7898 0.9996 1670008 ChemDiv1_023771 Cc1ccccc1NC(=O)c2c(NC(=O)c3ccncc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I12 compound treatment 622966.0 164000.0 0.34 624635.0 163000.0 0.35 0.4888 0.9998 1980794 ChemDiv1_023772 CC(C)CN(CC(C)C)CC(O)CN(c1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I13 compound treatment 2344043.0 1890000.0 3.89 2979884.0 2520000.0 5.45 6.6056 0.9864 1980795 ChemDiv1_023773 CCCCN1C=C(C(C[N+](=O)[O-])c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I14 compound treatment 641480.0 182000.0 0.38 635009.0 173000.0 0.38 0.5317 1.0 1980796 ChemDiv1_023774 CC(C)CN(CC(C)C)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I15 compound treatment 742029.0 283000.0 0.58 712959.0 251000.0 0.54 0.7977 0.9994 1297004 ChemDiv1_023775 CN1C(=O)C(OC(=O)C)N=C(c2ccccc2Cl)c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I16 compound treatment 710550.0 252000.0 0.52 699634.0 238000.0 0.52 0.7314 1.0 1980797 ChemDiv1_023776 Cc1ccc(cc1)N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I17 compound treatment 714680.0 256000.0 0.53 721234.0 260000.0 0.56 0.7705 0.9995 1167358 ChemDiv1_023777 CN1C(=O)C(O)N=C(c2ccccc2)c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I18 compound treatment 654261.0 195000.0 0.4 677174.0 216000.0 0.47 0.6148 0.9973 1523831 ChemDiv1_023778 CC1CC(C)CN(C1)S(=O)(=O)c2ccc-3c(c2)C(=O)c4cc(ccc43)S(=O)(=O)N5CC(C)CC(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I19 compound treatment 1377587.0 919000.0 1.9 1569010.0 1110000.0 2.4 3.0356 0.9933 1980798 ChemDiv1_023779 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I20 compound treatment 703694.0 245000.0 0.51 701353.0 240000.0 0.52 0.724 0.9999 1980799 ChemDiv1_023780 CCC(CC)C(=O)N1c2cc(C)c(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I21 compound treatment 706213.0 247000.0 0.51 716127.0 254000.0 0.55 0.7503 0.9993 1980800 ChemDiv1_023781 Cc1cc(c(C)cc1Br)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I22 compound treatment 691433.0 232000.0 0.48 701781.0 240000.0 0.52 0.7068 0.9992 1228310 ChemDiv1_023782 COC(=O)c1cc(=O)n2c3ccc(C)cc3sc2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I23 mock treatment 690636.0 232000.0 0.48 682292.0 221000.0 0.48 0.6758 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 I24 mock treatment 235528.0 -223000.0 -0.46 227654.0 -234000.0 -0.51 -0.6843 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J01 compound treatment 660178.0 201000.0 0.42 619387.0 158000.0 0.34 0.535 0.9953 1726654 ChemDiv1_023783 OC(=O)c1c(sc2nncc(=O)n12)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J02 compound treatment 669173.0 210000.0 0.43 636937.0 175000.0 0.38 0.575 0.9978 1416997 ChemDiv1_023784 Cc1cc2N(C(=O)c3ccc(F)cc3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J03 compound treatment 708598.0 250000.0 0.52 670763.0 209000.0 0.45 0.6844 0.9979 1980801 ChemDiv1_023785 [O-][N+](=O)c1ccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J04 compound treatment 675147.0 216000.0 0.45 671398.0 210000.0 0.45 0.6365 1.0 1980802 ChemDiv1_023786 Brc1cccc(c1)C(=O)N2c3ccccc3Sc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J05 compound treatment 701505.0 242000.0 0.5 715872.0 254000.0 0.55 0.743 0.9989 1786526 ChemDiv1_023787 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccc(OC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J06 compound treatment 660097.0 201000.0 0.42 643246.0 182000.0 0.39 0.5714 0.9996 1259978 ChemDiv1_023788 CCOc1ccc2-c3c(ssc3=Nc4ccccc4)C(C)(C)Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J07 compound treatment 721244.0 262000.0 0.54 728111.0 266000.0 0.58 0.7906 0.9995 1786528 ChemDiv1_023789 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccccc6OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J08 compound treatment 681045.0 222000.0 0.46 629439.0 168000.0 0.36 0.5809 0.9934 1980803 ChemDiv1_023790 CCCCc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J09 compound treatment 706911.0 248000.0 0.51 666557.0 205000.0 0.44 0.6755 0.9975 1980804 ChemDiv1_023791 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)OCCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J10 compound treatment 705975.0 247000.0 0.51 707605.0 246000.0 0.53 0.7369 0.9998 1293709 ChemDiv1_023792 Cc1c(Cl)cccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J11 compound treatment 699239.0 240000.0 0.5 722048.0 260000.0 0.56 0.7492 0.998 1144693 ChemDiv1_023793 CC1(CN2CC3(C)CN(C1)C2c4c[nH]c5ccccc45)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J12 compound treatment 722449.0 263000.0 0.54 702972.0 241000.0 0.52 0.7539 0.9998 1980805 ChemDiv1_023794 CCC(=O)N1c2ccccc2C3=C(SC(=C(C(=O)OC)C43SC(=C(S4)C(=O)OC)C(=O)OC)C(=O)OC)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J13 compound treatment 719400.0 260000.0 0.54 696855.0 235000.0 0.51 0.7401 0.9996 1482491 ChemDiv1_023795 O=c1[nH]c(Cc2ccccc2)nc3-c4ccccc4CC5(CCCCC5)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J14 compound treatment 702552.0 244000.0 0.5 712358.0 251000.0 0.54 0.7392 0.9993 1643966 ChemDiv1_023796 CCOc1ccccc1N=c2ssc3c2-c4cc(C)ccc4NC3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J15 compound treatment 736154.0 277000.0 0.57 716575.0 255000.0 0.55 0.7947 0.9998 1132573 ChemDiv1_023797 Clc1ccccc1C(=O)N2c3ccccc3Sc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J16 compound treatment 755754.0 297000.0 0.61 692909.0 231000.0 0.5 0.7871 0.995 1980806 ChemDiv1_023798 Cc1cc2NC(C)(C)c3sn(c4ccc(Cl)c(c4)C(F)(F)F)c(=S)c3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J17 compound treatment 700437.0 241000.0 0.5 712474.0 251000.0 0.54 0.7363 0.9991 1544356 ChemDiv1_023799 Cc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5ccc(F)cc5)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J18 compound treatment 703397.0 244000.0 0.5 702613.0 241000.0 0.52 0.7255 0.9999 1980807 ChemDiv1_023800 CC(=O)C1=C(S/C(=C\2/C(=S)C(C)(C)Nc3cc(C)c(C)cc23)/S1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J19 compound treatment 760255.0 301000.0 0.62 737656.0 276000.0 0.6 0.8621 0.9998 1779459 ChemDiv1_023801 Cn1c2N=C3C(C(c4cc(ccc4O)[N+](=O)[O-])c2c(=O)n(C)c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J20 compound treatment 697202.0 238000.0 0.49 697848.0 236000.0 0.51 0.7092 0.9998 1342318 ChemDiv1_023802 CCOc1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J21 compound treatment 759633.0 301000.0 0.62 723813.0 262000.0 0.57 0.84 0.999 1365609 ChemDiv1_023803 Cc1ccc(CN2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J22 compound treatment 714214.0 255000.0 0.53 688228.0 227000.0 0.49 0.7193 0.9994 1171881 ChemDiv1_023804 CCOc1ccc2N(C(=O)CSc3nccn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J23 mock treatment 706255.0 247000.0 0.51 683738.0 222000.0 0.48 0.7008 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 J24 mock treatment 196040.0 -263000.0 -0.54 241759.0 -220000.0 -0.48 -0.7204 -0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K01 compound treatment 653198.0 194000.0 0.4 621822.0 160000.0 0.35 0.5286 0.9974 1980808 ChemDiv1_023805 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4C(F)(F)F)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K02 compound treatment 651813.0 193000.0 0.4 637787.0 176000.0 0.38 0.551 0.9998 1980809 ChemDiv1_023806 CC(=O)N[C@H]1[C@H](Oc2ccc(NC(=O)C)cc2)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K03 compound treatment 678832.0 220000.0 0.45 697999.0 236000.0 0.51 0.6826 0.9982 1622825 ChemDiv1_023807 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4cc(OC)c(OC)c(OC)c4)C(=O)CCC3)c5ccccc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K04 compound treatment 646499.0 187000.0 0.39 693481.0 232000.0 0.5 0.6285 0.9918 1980810 ChemDiv1_023808 CCCCCCCCNC(=O)c1ccccc1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K05 compound treatment 670060.0 211000.0 0.44 657157.0 196000.0 0.42 0.6073 0.9999 1725179 ChemDiv1_023809 Brc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K06 compound treatment 669567.0 211000.0 0.43 667613.0 206000.0 0.45 0.6226 0.9999 1980811 ChemDiv1_023810 COc1ccccc1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K07 compound treatment 680829.0 222000.0 0.46 671426.0 210000.0 0.45 0.6448 1.0 1224814 ChemDiv1_023811 Cc1c(C)c2ccccc2n1CC(O)CN3CCN(Cc4ccccc4)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K08 compound treatment 689881.0 231000.0 0.48 693764.0 232000.0 0.5 0.6922 0.9997 1980812 ChemDiv1_023812 COc1ccc(cc1N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K09 compound treatment 880641.0 422000.0 0.87 697177.0 236000.0 0.51 0.9759 0.9675 1980813 ChemDiv1_023813 CCOC(=O)C1=C(Nc2ccc(OCC)cc2)S/C(=C\c3ccc(OCC)c(OCC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K10 compound treatment 657327.0 198000.0 0.41 678851.0 217000.0 0.47 0.6219 0.9976 1980814 ChemDiv1_023814 COc1ccc(cc1N(CC(O)CN(CC(C)C)CC(C)C)S(=O)(=O)c2ccccc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K11 compound treatment 723477.0 264000.0 0.55 730243.0 269000.0 0.58 0.7971 0.9995 1247334 ChemDiv1_023815 O=C(Nc1ccccc1)c2c(NC(=O)c3ccncc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K12 compound treatment 669795.0 211000.0 0.44 677859.0 216000.0 0.47 0.6386 0.9993 1980815 ChemDiv1_023816 CCCCN(CCCC)CC(O)CN(c1ccc(OC)cc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K13 compound treatment 721163.0 262000.0 0.54 733535.0 272000.0 0.59 0.7988 0.9991 1980816 ChemDiv1_023817 CN1C=C(Cc2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K14 compound treatment 658826.0 200000.0 0.41 634634.0 173000.0 0.37 0.5564 0.9988 1980817 ChemDiv1_023818 CCCCN(CCCC)CC(O)CN(c1ccccc1OC)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K15 compound treatment 699684.0 241000.0 0.5 712022.0 250000.0 0.54 0.7345 0.9991 1475953 ChemDiv1_023819 CC(=O)OC1N=C(c2ccc(Cl)cc2)c3cc(Br)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K16 compound treatment 590219.0 131000.0 0.27 595045.0 133000.0 0.29 0.3957 0.9995 1928679 ChemDiv1_023820 CC(C)CN(CC(C)C)CC(O)CN(c1cccc(C)c1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K17 compound treatment 739992.0 281000.0 0.58 735116.0 273000.0 0.59 0.8287 0.9999 1451786 ChemDiv1_023821 CN1C(=O)C(OC(=O)C)N=C(c2ccccc2)c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K18 compound treatment 672910.0 214000.0 0.44 691458.0 230000.0 0.5 0.6639 0.9982 1556847 ChemDiv1_023822 COc1ccc(cc1)C2N(CCN2S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K19 compound treatment 709243.0 250000.0 0.52 729846.0 268000.0 0.58 0.7757 0.9983 1948294 ChemDiv1_023823 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3cccc(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K20 compound treatment 654164.0 195000.0 0.4 707139.0 245000.0 0.53 0.6606 0.9907 1980818 ChemDiv1_023824 CCC(CC)C(=O)N1c2cc(C)c(C)cc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K21 compound treatment 704002.0 245000.0 0.51 698120.0 236000.0 0.51 0.7195 1.0 1336862 ChemDiv1_023825 Cc1cc(ccc1Cl)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)c(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K22 compound treatment 698292.0 239000.0 0.49 682924.0 221000.0 0.48 0.6879 0.9999 1577868 ChemDiv1_023826 COC(=O)c1cc(=O)n2c3cc(C)c(C)cc3sc2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K23 mock treatment 655911.0 197000.0 0.41 662530.0 201000.0 0.43 0.5948 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 K24 mock treatment 223999.0 -235000.0 -0.49 236596.0 -225000.0 -0.49 -0.6875 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L01 compound treatment 657636.0 199000.0 0.41 620962.0 159000.0 0.34 0.5337 0.9963 1267672 ChemDiv1_023827 Cc1nnc2sc(C(=O)Nc3ccccc3)c(C(=O)O)n2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L02 compound treatment 667424.0 208000.0 0.43 642078.0 180000.0 0.39 0.5803 0.9988 1724400 ChemDiv1_023828 Cc1cc2N(C(=O)c3cccc(F)c3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L03 compound treatment 687057.0 228000.0 0.47 694223.0 233000.0 0.5 0.6888 0.9994 1980819 ChemDiv1_023829 [O-][N+](=O)c1cccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L04 compound treatment 669753.0 211000.0 0.44 656630.0 195000.0 0.42 0.606 0.9999 1980820 ChemDiv1_023830 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)c4cccc(Br)c4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L05 compound treatment 662203.0 203000.0 0.42 707305.0 246000.0 0.53 0.6726 0.9931 1786527 ChemDiv1_023831 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L06 compound treatment 667978.0 209000.0 0.43 623662.0 162000.0 0.35 0.553 0.9947 1980821 ChemDiv1_023832 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4cccc(Cl)c4Cl)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L07 compound treatment 728375.0 269000.0 0.56 696503.0 235000.0 0.51 0.7526 0.999 1980822 ChemDiv1_023833 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6cc(C)ccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L08 compound treatment 687272.0 228000.0 0.47 702951.0 241000.0 0.52 0.7025 0.9987 1980823 ChemDiv1_023834 Cc1cc2NC(C)(C)c3sn(c4cccc(c4)C(F)(F)F)c(=S)c3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L09 compound treatment 651386.0 192000.0 0.4 663409.0 202000.0 0.44 0.5896 0.9989 1980824 ChemDiv1_023835 CCCCOC(=O)C(CCCC)N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L10 compound treatment 686319.0 227000.0 0.47 713828.0 252000.0 0.55 0.7177 0.9972 1449908 ChemDiv1_023836 Cc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5cccc(Cl)c5C)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L11 compound treatment 746384.0 287000.0 0.59 718714.0 257000.0 0.56 0.8129 0.9995 1546929 ChemDiv1_023837 CC1(N2CC3(C)CN1CC(C)(C2)C3=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L12 compound treatment 687101.0 228000.0 0.47 662148.0 201000.0 0.43 0.6398 0.9992 1980825 ChemDiv1_023838 CC(C)C(=O)N1c2ccccc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L13 compound treatment 701311.0 242000.0 0.5 676998.0 215000.0 0.47 0.6833 0.9994 1250103 ChemDiv1_023839 Cn1c(Cc2ccccc2)nc3-c4ccccc4CC5(CCCCC5)c3c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L14 compound treatment 754638.0 296000.0 0.61 641889.0 180000.0 0.39 0.7074 0.9766 1172524 ChemDiv1_023840 CCOc1ccccc1N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L15 compound treatment 762996.0 304000.0 0.63 731938.0 270000.0 0.59 0.8574 0.9994 1413273 ChemDiv1_023841 O=C(N1c2ccccc2CCc3ccccc13)c4ccc(cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L16 compound treatment 736969.0 278000.0 0.57 714241.0 253000.0 0.55 0.7923 0.9997 1980826 ChemDiv1_023842 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cccc(OC)c4N(C(=O)Cc5ccccc5)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L17 compound treatment 716111.0 257000.0 0.53 753159.0 292000.0 0.63 0.8214 0.9963 1527972 ChemDiv1_023843 Fc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L18 compound treatment 715863.0 257000.0 0.53 676444.0 215000.0 0.46 0.7037 0.9979 1980827 ChemDiv1_023844 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)COc3ccccc3)c4ccc(OC)cc24)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L19 compound treatment 796623.0 338000.0 0.7 742104.0 280000.0 0.61 0.922 0.9976 1125680 ChemDiv1_023845 Cn1c2N=C3C(C(c4ccc(Cl)cc4Cl)c2c(=O)n(C)c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L20 compound treatment 661949.0 203000.0 0.42 711110.0 249000.0 0.54 0.678 0.9921 1872650 ChemDiv1_023846 Cc1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L21 compound treatment 746985.0 288000.0 0.59 721627.0 260000.0 0.56 0.8182 0.9996 1980828 ChemDiv1_023847 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccccc4Cl)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L22 compound treatment 716335.0 257000.0 0.53 697414.0 236000.0 0.51 0.7364 0.9998 1980829 ChemDiv1_023848 Cc1ccc2N(C(=O)CSc3nccn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L23 mock treatment 700711.0 242000.0 0.5 685029.0 223000.0 0.48 0.6947 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 L24 mock treatment 203412.0 -256000.0 -0.53 215559.0 -246000.0 -0.53 -0.7497 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M01 compound treatment 634262.0 175000.0 0.36 609853.0 148000.0 0.32 0.4826 0.9982 1980830 ChemDiv1_023849 COc1ccc(OC)c(c1)N2C(=C(C(C3=C2CC(C)(C)CC3=O)c4cc(OC)c(OC)c(OC)c4)C(=O)c5ccccc5)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M02 compound treatment 627654.0 169000.0 0.35 642090.0 180000.0 0.39 0.5223 0.9984 1980831 ChemDiv1_023850 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M03 compound treatment 636996.0 178000.0 0.37 680901.0 219000.0 0.47 0.5954 0.992 1375024 ChemDiv1_023851 COc1ccc(cc1)C(=O)C2=C(N)N(C3=C(C2c4ccc5OCOc5c4)C(=O)CCC3)c6ccccc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M04 compound treatment 640343.0 181000.0 0.37 664441.0 203000.0 0.44 0.575 0.9969 1980832 ChemDiv1_023852 COc1ccccc1O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M05 compound treatment 688071.0 229000.0 0.47 668626.0 207000.0 0.45 0.6511 0.9996 1980833 ChemDiv1_023853 CCOC(=O)C1=C(Nc2ccc(C)cc2)S/C(=C\c3ccccc3OCC(=O)O)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M06 compound treatment 655239.0 196000.0 0.41 625437.0 164000.0 0.35 0.5371 0.9978 1980834 ChemDiv1_023854 OCC1OC(Oc2cccc3ccccc23)C(O)C(O)C1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M07 compound treatment 701755.0 243000.0 0.5 673512.0 212000.0 0.46 0.6786 0.999 1537037 ChemDiv1_023855 O=C1CC(=Nc2ccccc2N1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M08 compound treatment 690000.0 231000.0 0.48 683350.0 222000.0 0.48 0.6765 1.0 1980835 ChemDiv1_023856 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M09 compound treatment 704902.0 246000.0 0.51 666529.0 205000.0 0.44 0.6725 0.9977 1948383 ChemDiv1_023857 Cc1cc(F)c(F)cc1C(=O)N2CCN(CC2)c3cc(N4CCCCC4)c(F)cc3[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M10 compound treatment 599611.0 141000.0 0.29 635716.0 174000.0 0.38 0.4716 0.9917 1980836 ChemDiv1_023858 COc1ccc(cc1)N(CC(O)CN(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M11 compound treatment 729691.0 271000.0 0.56 715278.0 254000.0 0.55 0.7833 1.0 1720587 ChemDiv1_023859 COc1ccc(NC(=O)c2c(NC(=O)CCC(=O)O)sc3CCCc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M12 compound treatment 654940.0 196000.0 0.4 684848.0 223000.0 0.48 0.6276 0.9961 1980837 ChemDiv1_023860 COc1ccc(cc1N(CC(O)CN(CC(C)C)CC(C)C)S(=O)(=O)c2ccc(C)cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M13 compound treatment 751903.0 293000.0 0.6 742502.0 281000.0 0.61 0.8574 1.0 1980838 ChemDiv1_023861 CCN1C=C(C(C#N)c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M14 compound treatment 668232.0 209000.0 0.43 655216.0 194000.0 0.42 0.6016 0.9999 1980839 ChemDiv1_023862 CCCCN(CCCC)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M15 compound treatment 702199.0 243000.0 0.5 697122.0 235000.0 0.51 0.7154 1.0 1404879 ChemDiv1_023863 OC1N=C(c2ccc(Cl)cc2)c3cc(Br)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M16 compound treatment 656553.0 198000.0 0.41 663610.0 202000.0 0.44 0.5974 0.9994 1980840 ChemDiv1_023864 CCCCN(CCCC)CC(O)CN(c1ccccc1OC)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M17 compound treatment 683379.0 224000.0 0.46 708785.0 247000.0 0.53 0.7057 0.9974 1946090 ChemDiv1_023865 CCOC(=O)C1=C(Nc2ccc(F)cc2)S/C(=C\c3ccccc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M18 compound treatment 686339.0 227000.0 0.47 708457.0 247000.0 0.53 0.7095 0.9979 1488125 ChemDiv1_023866 COc1ccc(cc1)C2N(CCN2S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M19 compound treatment 735279.0 276000.0 0.57 732455.0 271000.0 0.59 0.8177 0.9999 1980841 ChemDiv1_023867 CCOC(=O)C1=C(Nc2ccc(C)cc2)S/C(=C/c3cc(OC)c(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M20 compound treatment 671361.0 212000.0 0.44 695264.0 234000.0 0.51 0.6675 0.9975 1980842 ChemDiv1_023868 CC1CCN(CC(=O)N2c3ccc(C)cc3-c4c(ssc4=S)C2(C)C)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M21 compound treatment 696016.0 237000.0 0.49 710460.0 249000.0 0.54 0.7267 0.9989 1169518 ChemDiv1_023869 COc1ccc(cc1OC)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M22 compound treatment 714664.0 256000.0 0.53 662767.0 201000.0 0.44 0.681 0.9954 1398951 ChemDiv1_023870 CCOc1ccc2c(c1)sc3nc(cc(=O)n23)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M23 mock treatment 664240.0 205000.0 0.42 685252.0 224000.0 0.48 0.6418 0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 M24 mock treatment 219444.0 -240000.0 -0.49 363764.0 -97900.0 -0.21 -0.4995 -0.9284 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N01 compound treatment 654771.0 196000.0 0.4 602422.0 141000.0 0.3 0.5012 0.9903 1378621 ChemDiv1_023871 Clc1cccc2c1ncc3c(=O)n4ccsc4nc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N02 compound treatment 655065.0 196000.0 0.4 660756.0 199000.0 0.43 0.5909 0.9995 1980843 ChemDiv1_023872 Cc1cc2N(C(=O)c3ccccc3Cl)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N03 compound treatment 667936.0 209000.0 0.43 698095.0 236000.0 0.51 0.6668 0.9964 1980844 ChemDiv1_023873 Clc1ccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N04 compound treatment 650070.0 191000.0 0.39 652518.0 191000.0 0.41 0.571 0.9997 1980845 ChemDiv1_023874 CC1(C)N(C(=O)C=C)c2ccccc2-c3c1ssc3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N05 compound treatment 664473.0 205000.0 0.42 697082.0 235000.0 0.51 0.6602 0.9958 1980846 ChemDiv1_023875 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6cccc(C)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N06 compound treatment 673248.0 214000.0 0.44 659677.0 198000.0 0.43 0.6158 0.9999 1980847 ChemDiv1_023876 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6cccc(Cl)c6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N07 compound treatment 684693.0 226000.0 0.47 667696.0 206000.0 0.45 0.6448 0.9998 1529808 ChemDiv1_023877 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6cccc(Cl)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N08 compound treatment 636223.0 177000.0 0.37 681718.0 220000.0 0.48 0.5955 0.9915 1489394 ChemDiv1_023878 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccc(C)cc4-c5c(ssc5=S)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N09 compound treatment 705459.0 246000.0 0.51 688970.0 227000.0 0.49 0.7076 0.9999 1980848 ChemDiv1_023879 COc1ccc(cc1)C(=O)N/C(=C\c2ccc3OCOc3c2)/C(=O)Nc4ccc(cc4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N10 compound treatment 659420.0 200000.0 0.41 671660.0 210000.0 0.45 0.6139 0.9989 1634240 ChemDiv1_023880 Cc1c(Cl)cccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N11 compound treatment 705609.0 247000.0 0.51 710978.0 249000.0 0.54 0.7415 0.9996 1519540 ChemDiv1_023881 O=C(N1CCOCC1)N2c3ccccc3C=Cc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N12 compound treatment 657161.0 198000.0 0.41 617956.0 156000.0 0.34 0.5285 0.9956 1668642 ChemDiv1_023882 CCCC(=O)N1c2c(C)cc(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N13 compound treatment 717213.0 258000.0 0.53 688307.0 227000.0 0.49 0.7238 0.9991 1980849 ChemDiv1_023883 O=c1[nH]c(CN2CCCC2)nc3-c4ccccc4CC5(CCCC5)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N14 compound treatment 637935.0 179000.0 0.37 680114.0 218000.0 0.47 0.5955 0.9925 1980850 ChemDiv1_023884 COc1ccc(OC)c(N=c2ssc3c2-c4ccccc4NC3(C)C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N15 compound treatment 666865.0 208000.0 0.43 664593.0 203000.0 0.44 0.614 0.9999 1424281 ChemDiv1_023885 Clc1cccc(c1)C(=O)N2c3ccccc3CCc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N16 compound treatment 691419.0 232000.0 0.48 687523.0 226000.0 0.49 0.6849 1.0 1980851 ChemDiv1_023886 CCCC(=O)N1c2cc(C)ccc2C(=C3SC(=C(S3)C(=O)OCC)C(=O)OCC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N17 compound treatment 702562.0 244000.0 0.5 747495.0 286000.0 0.62 0.793 0.9947 1568573 ChemDiv1_023887 Clc1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N18 compound treatment 681304.0 222000.0 0.46 709035.0 247000.0 0.54 0.7031 0.997 1870698 ChemDiv1_023888 CN1c2ccc(C)cc2-c3c(ssc3=Nc4cccc(Cl)c4)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N19 compound treatment 709046.0 250000.0 0.52 700512.0 239000.0 0.52 0.7305 1.0 1305305 ChemDiv1_023889 Cn1c2N=C3C(C(c4cccc(I)c4)c2c(=O)n(C)c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N20 compound treatment 701975.0 243000.0 0.5 763074.0 301000.0 0.65 0.816 0.9916 1176806 ChemDiv1_023890 CC(C)c1ccc(cc1)n2sc3c(-c4cc(C)ccc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N21 compound treatment 706921.0 248000.0 0.51 711565.0 250000.0 0.54 0.7443 0.9996 1980852 ChemDiv1_023891 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccc(Cl)cc4Cl)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N22 compound treatment 699072.0 240000.0 0.5 694973.0 233000.0 0.51 0.7075 1.0 1782439 ChemDiv1_023892 Cc1ccc2N(Cc3ccccc3)C(C)(C)c4sn(c5ccc(C)c(C)c5)c(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N23 mock treatment 681521.0 223000.0 0.46 684863.0 223000.0 0.48 0.6664 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 N24 mock treatment 365628.0 -93400.0 -0.19 205213.0 -256000.0 -0.56 -0.5288 -0.9 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O01 compound treatment 633904.0 175000.0 0.36 579781.0 118000.0 0.26 0.4361 0.9857 1656444 ChemDiv1_023893 COc1ccc(OC)c(c1)N2C(=C(C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)C(=O)c6ccccc6)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O02 compound treatment 671291.0 212000.0 0.44 621098.0 159000.0 0.35 0.5539 0.993 1980853 ChemDiv1_023894 CC(=O)N[C@H]1[C@H](Oc2ccc(C)cc2)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O03 compound treatment 678779.0 220000.0 0.45 663948.0 202000.0 0.44 0.6304 0.9998 1537610 ChemDiv1_023895 COc1cccc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(Br)c4)C(=O)c5ccccc5)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O04 compound treatment 646408.0 187000.0 0.39 635716.0 174000.0 0.38 0.5399 0.9999 1980854 ChemDiv1_023896 CC(=O)N[C@H]1[C@H](Oc2ccccc2C(=O)NCc3ccccc3)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O05 compound treatment 666249.0 207000.0 0.43 654587.0 193000.0 0.42 0.5978 0.9999 1980855 ChemDiv1_023897 CCOC(=O)C1=C(Nc2ccc(OC)cc2)S/C(=C\c3ccc(OCC(=O)O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O06 compound treatment 638534.0 180000.0 0.37 620192.0 159000.0 0.34 0.5047 0.9993 1980856 ChemDiv1_023898 OC[C@H]1O[C@@H](Oc2ccc3ccccc3c2)[C@H](O)[C@@H](O)[C@@H]1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O07 compound treatment 683742.0 225000.0 0.46 647662.0 186000.0 0.4 0.6127 0.9975 1732908 ChemDiv1_023899 Cc1ccc2N=C(CC(=O)Nc2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O08 compound treatment 561406.0 102000.0 0.21 575751.0 114000.0 0.25 0.3241 0.997 1980857 ChemDiv1_023900 CC(C)CN(CC(C)C)CC(O)CN(c1cccc(C)c1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O09 compound treatment 646958.0 188000.0 0.39 639003.0 177000.0 0.38 0.5458 1.0 1948348 ChemDiv1_023901 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4ccccc4F)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O10 compound treatment 577563.0 119000.0 0.24 549577.0 87900.0 0.19 0.3076 0.9923 1980858 ChemDiv1_023902 COc1ccc(cc1)N(CC(O)CN(CC(C)C)CC(C)C)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O11 compound treatment 666180.0 207000.0 0.43 673714.0 212000.0 0.46 0.627 0.9994 1129577 ChemDiv1_023903 Fc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O12 compound treatment 596295.0 137000.0 0.28 577105.0 115000.0 0.25 0.3771 0.998 1980859 ChemDiv1_023904 Cc1ccc(cc1)N(CC(O)CN(CC=C)CC=C)S(=O)(=O)c2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O13 compound treatment 2019728.0 1560000.0 3.22 2208036.0 1750000.0 3.78 4.9509 0.9968 1980860 ChemDiv1_023905 CCN1C=C(C(C[N+](=O)[O-])c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O14 compound treatment 642389.0 183000.0 0.38 633488.0 172000.0 0.37 0.5307 1.0 1980861 ChemDiv1_023906 CCCCN(CCCC)CC(O)CN(c1ccccc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O15 compound treatment 682548.0 224000.0 0.46 641745.0 180000.0 0.39 0.6019 0.9965 1435700 ChemDiv1_023907 OC1N=C(c2ccccc2)c3ccccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O16 compound treatment 631184.0 172000.0 0.36 645556.0 184000.0 0.4 0.5328 0.9984 1370384 ChemDiv1_023908 CC(C)CN(CC(C)C)Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O17 compound treatment 711922.0 253000.0 0.52 697208.0 236000.0 0.51 0.7297 0.9999 1980862 ChemDiv1_023909 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C/c3cccc(O)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O18 compound treatment 660245.0 201000.0 0.42 667216.0 206000.0 0.44 0.6083 0.9994 1130464 ChemDiv1_023910 CCOc1ccc2NC(C)(C)c3ssc(=Nc4cccc(NC(=O)C)c4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O19 compound treatment 668158.0 209000.0 0.43 685788.0 224000.0 0.49 0.6483 0.9983 1948110 ChemDiv1_023911 CCOC(=O)C1=C(Nc2ccc(C)cc2)S/C(=C\c3ccc(C)cc3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O20 compound treatment 656611.0 198000.0 0.41 665536.0 204000.0 0.44 0.6005 0.9992 1429695 ChemDiv1_023912 CCOc1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O21 compound treatment 697031.0 238000.0 0.49 684343.0 223000.0 0.48 0.6883 1.0 1636512 ChemDiv1_023913 CCOc1ccc(Br)cc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O22 compound treatment 647540.0 189000.0 0.39 643992.0 182000.0 0.39 0.5543 1.0 1980863 ChemDiv1_023914 Cc1cc2N(C(=O)c3cccc(c3)[N+](=O)[O-])C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O23 mock treatment 660707.0 202000.0 0.42 721908.0 260000.0 0.56 0.6927 0.9889 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 O24 mock treatment 386572.0 -72400.0 -0.15 277436.0 -184000.0 -0.4 -0.3877 -0.9104 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P01 compound treatment 654683.0 196000.0 0.4 580523.0 119000.0 0.26 0.4675 0.9763 1565964 ChemDiv1_023915 Cc1ccc(cc1)S(=O)(=O)c2nc(Cc3ccccc3)oc2NCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P02 compound treatment 667742.0 209000.0 0.43 616629.0 155000.0 0.34 0.5419 0.9923 1157860 ChemDiv1_023916 CC1(C)N(C(=O)CN2C(=O)CCC2=O)c3ccccc3-c4c1ssc4=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P03 compound treatment 632711.0 174000.0 0.36 602117.0 140000.0 0.3 0.4685 0.9966 1980864 ChemDiv1_023917 Clc1cccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P04 compound treatment 637691.0 179000.0 0.37 590310.0 129000.0 0.28 0.4577 0.9904 1980865 ChemDiv1_023918 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)C=C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P05 compound treatment 631936.0 173000.0 0.36 609337.0 148000.0 0.32 0.4784 0.9985 1980866 ChemDiv1_023919 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P06 compound treatment 631833.0 173000.0 0.36 612255.0 151000.0 0.33 0.4828 0.999 1780399 ChemDiv1_023920 COc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6cccc(Cl)c6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P07 compound treatment 641689.0 183000.0 0.38 629698.0 168000.0 0.36 0.5238 0.9998 1526987 ChemDiv1_023921 CCCCC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)Nc6ccc(C)c(Cl)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P08 compound treatment 623380.0 164000.0 0.34 601727.0 140000.0 0.3 0.4543 0.9984 1781655 ChemDiv1_023922 CCCCc1ccc(cc1)n2sc3c(-c4cccc(C)c4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P09 compound treatment 674962.0 216000.0 0.45 632491.0 171000.0 0.37 0.5767 0.9957 1980867 ChemDiv1_023923 COc1ccc(cc1)C(=O)N/C(=C\c2ccc3OCOc3c2)/C(=O)Nc4cccc(c4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P10 compound treatment 667064.0 208000.0 0.43 627646.0 166000.0 0.36 0.5577 0.9961 1308777 ChemDiv1_023924 Cc1c(Cl)cccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P11 compound treatment 676885.0 218000.0 0.45 640819.0 179000.0 0.39 0.5922 0.9973 1203812 ChemDiv1_023925 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)OC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P12 compound treatment 662262.0 203000.0 0.42 637290.0 176000.0 0.38 0.5655 0.9988 1980868 ChemDiv1_023926 Cc1ccc2-c3c(ssc3=Nc4cccc(Cl)c4)C(C)(C)N(Cc5ccccc5)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P13 compound treatment 661146.0 202000.0 0.42 637998.0 176000.0 0.38 0.5649 0.999 1687761 ChemDiv1_023927 COc1ccc(cc1OC)C2(CN)CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P14 compound treatment 658740.0 200000.0 0.41 634420.0 173000.0 0.37 0.556 0.9988 1980869 ChemDiv1_023928 CCc1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P15 compound treatment 664611.0 206000.0 0.42 619431.0 158000.0 0.34 0.5416 0.9942 1537452 ChemDiv1_023929 CCCC(=O)N1c2cc(C)c(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P16 compound treatment 697596.0 239000.0 0.49 629476.0 168000.0 0.36 0.6051 0.9888 1980870 ChemDiv1_023930 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CC(C)C)c3cc(C)ccc23)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P17 compound treatment 722930.0 264000.0 0.54 626688.0 165000.0 0.36 0.6378 0.9791 1334003 ChemDiv1_023931 Clc1ccccc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P18 compound treatment 701811.0 243000.0 0.5 647827.0 186000.0 0.4 0.6393 0.9942 1870666 ChemDiv1_023932 CCOc1ccc2N(C)C(C)(C)c3ssc(=Nc4ccc(C)cc4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P19 compound treatment 701500.0 242000.0 0.5 648410.0 187000.0 0.4 0.6398 0.9944 1415605 ChemDiv1_023933 Cc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P20 compound treatment 685160.0 226000.0 0.47 646564.0 185000.0 0.4 0.6131 0.9971 1657687 ChemDiv1_023934 CC(C)c1ccc(cc1)n2sc3c(-c4ccc(C)cc4NC3(C)C)c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P21 compound treatment 654949.0 196000.0 0.4 604051.0 142000.0 0.31 0.5039 0.991 1980871 ChemDiv1_023935 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccc(F)cc4)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P22 compound treatment 673300.0 214000.0 0.44 626639.0 165000.0 0.36 0.5653 0.9944 1980872 ChemDiv1_023936 Cc1ccc2N(Cc3ccccc3)C(C)(C)c4sn(c5ccc(Br)cc5)c(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P23 mock treatment 645051.0 186000.0 0.38 596034.0 134000.0 0.29 0.4772 0.9906 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.654 P24 mock treatment 380163.0 -78900.0 -0.16 475958.0 14300.0 0.03 -0.0932 -0.5624 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A01 compound treatment 632549.0 169000.0 0.35 589430.0 127000.0 0.27 0.4407 0.9927 1300452 ChemDiv1_023937 Cc1cc2N(C(=O)COc3ccc(Cl)cc3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A02 compound treatment 639322.0 176000.0 0.36 591921.0 129000.0 0.28 0.4544 0.9915 1980873 ChemDiv1_023938 N#CCCNCC1(CCCC1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A03 compound treatment 662657.0 199000.0 0.41 602584.0 140000.0 0.3 0.5048 0.9885 1980874 ChemDiv1_023939 [O-][N+](=O)c1cccc(NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A04 compound treatment 638067.0 175000.0 0.36 596715.0 134000.0 0.29 0.4599 0.9941 1161042 ChemDiv1_023940 COc1ccc(cc1OC)C2(CCCC2)C(=O)NCC3(CCCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A05 compound treatment 700538.0 237000.0 0.49 630278.0 167000.0 0.36 0.6025 0.989 1138374 ChemDiv1_023941 Clc1cc(Cl)c2OC3(CCCCC3=Cc2c1)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A06 compound treatment 698040.0 235000.0 0.48 637897.0 175000.0 0.38 0.6105 0.9926 1089576 ChemDiv1_023942 CC1=C(C)CC(C(C1)C(=O)O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A07 compound treatment 708988.0 246000.0 0.51 643769.0 181000.0 0.39 0.6355 0.9918 1980875 ChemDiv1_023943 CCN1C2N(c3ccccc3C1N(c4ccccc24)S(=O)(=O)c5ccc(C)cc5)S(=O)(=O)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A08 compound treatment 720533.0 257000.0 0.53 665234.0 202000.0 0.44 0.6852 0.9954 1743248 ChemDiv1_023944 COc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc4ccc(F)cc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A09 compound treatment 699994.0 237000.0 0.49 647796.0 185000.0 0.4 0.6285 0.9951 1980876 ChemDiv1_023945 Cc1c(Cl)cccc1N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccc(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A10 compound treatment 685895.0 223000.0 0.46 654447.0 192000.0 0.41 0.6181 0.9987 1582140 ChemDiv1_023946 O=C1N(C(=O)c2c1sc3nnc(c4cccs4)c(=O)n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A11 compound treatment 698520.0 235000.0 0.49 647623.0 185000.0 0.4 0.6261 0.9953 1950755 ChemDiv1_023947 CCOC(=O)C1=NNC2(C1C(=O)N(C2=O)c3cccc(OC)c3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A12 compound treatment 695289.0 232000.0 0.48 630833.0 168000.0 0.36 0.5957 0.9907 1980877 ChemDiv1_023948 CC1(C)CC(=O)c2cc(C(=O)NCCCN3CCOCC3)c(=O)n(c4ccc(Cl)cc4)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A13 compound treatment 715570.0 252000.0 0.52 716096.0 253000.0 0.55 0.7558 0.9997 1734063 ChemDiv1_023949 Cc1ccc(cc1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A14 compound treatment 718303.0 255000.0 0.53 670852.0 208000.0 0.45 0.6905 0.997 1567325 ChemDiv1_023950 O=S(=O)(NC1C(N2CCN(CC2)C(=S)Nc3ccccc3)c4cccc5cccc1c45)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A15 compound treatment 712269.0 249000.0 0.51 674821.0 212000.0 0.46 0.6878 0.9984 1589203 ChemDiv1_023951 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A16 compound treatment 730492.0 267000.0 0.55 660933.0 198000.0 0.43 0.6931 0.9922 1386112 ChemDiv1_023952 Clc1ccc(cc1)S(=O)(=O)NC2C(N3CCOCC3)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A17 compound treatment 729174.0 266000.0 0.55 683534.0 221000.0 0.48 0.7258 0.9976 1491077 ChemDiv1_023953 Nc1ccccc1c2n[nH]c(=S)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A18 compound treatment 793119.0 330000.0 0.68 780502.0 318000.0 0.69 0.9675 1.0 1944410 ChemDiv1_023954 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccc(O)c(OCC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A19 compound treatment 665647.0 202000.0 0.42 642321.0 179000.0 0.39 0.57 0.9993 1352392 ChemDiv1_023955 Cc1ccc(OC2(OC(=O)c3ccccc32)c4ccccc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A20 compound treatment 669215.0 206000.0 0.43 631151.0 168000.0 0.36 0.5581 0.997 1980878 ChemDiv1_023956 CCCC(CCC)C(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCl)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A21 compound treatment 683893.0 221000.0 0.46 639253.0 176000.0 0.38 0.5919 0.9961 1466708 ChemDiv1_023957 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cccc(Br)c4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A22 compound treatment 675671.0 212000.0 0.44 601341.0 138000.0 0.3 0.5219 0.9828 1310577 ChemDiv1_023958 CCC1(C)CC(CCN(Cc2ccccc2)C(=O)C)(CCO1)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A23 mock treatment 623965.0 161000.0 0.33 584631.0 122000.0 0.26 0.4209 0.9935 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 A24 mock treatment 207611.0 -256000.0 -0.53 225245.0 -238000.0 -0.51 -0.7369 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B01 compound treatment 655991.0 193000.0 0.4 592502.0 130000.0 0.28 0.4796 0.9854 1980879 ChemDiv1_023959 CCOC(=O)C(=O)N1CCCc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B02 compound treatment 654305.0 191000.0 0.39 620822.0 158000.0 0.34 0.5205 0.9975 1980880 ChemDiv1_023960 COc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B03 compound treatment 698681.0 235000.0 0.49 689069.0 226000.0 0.49 0.6898 1.0 1980881 ChemDiv1_023961 Cc1ccc2c(c1)N(C(=O)/C=C/c3ccccc3)C(C)(C)CC2(C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B04 compound treatment 671412.0 208000.0 0.43 655145.0 192000.0 0.42 0.598 0.9999 1980882 ChemDiv1_023962 CNC(=O)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B05 compound treatment 702148.0 239000.0 0.49 691012.0 228000.0 0.49 0.6978 1.0 1980883 ChemDiv1_023963 CCOc1ccc-2c(c1)C(=NNC(=O)c3ccncc3)c4cc(OCC)ccc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B06 compound treatment 662917.0 200000.0 0.41 681680.0 219000.0 0.47 0.6262 0.9976 1980884 ChemDiv1_023964 FC(F)(F)c1cccc(NC(=O)C(=O)NCC=C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B07 compound treatment 727590.0 264000.0 0.55 688135.0 225000.0 0.49 0.7305 0.9984 1980885 ChemDiv1_023965 Cc1nc2sccn2c(=O)c1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B08 compound treatment 719346.0 256000.0 0.53 666580.0 204000.0 0.44 0.6855 0.9959 1703065 ChemDiv1_023966 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCc4ccccc4F)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B09 compound treatment 769819.0 307000.0 0.63 711167.0 248000.0 0.54 0.8274 0.9967 1451675 ChemDiv1_023967 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B10 compound treatment 617723.0 154000.0 0.32 630850.0 168000.0 0.36 0.4825 0.9979 1703682 ChemDiv1_023968 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3OCC(=O)O)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B11 compound treatment 750383.0 287000.0 0.59 715522.0 253000.0 0.55 0.8057 0.9992 1705360 ChemDiv1_023969 Cc1cc(=O)oc2c3CN(COc3ccc12)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B12 compound treatment 708213.0 245000.0 0.51 681790.0 219000.0 0.47 0.6925 0.9995 1684797 ChemDiv1_023970 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(Br)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B13 compound treatment 715013.0 252000.0 0.52 716171.0 253000.0 0.55 0.7551 0.9996 1554312 ChemDiv1_023971 Cc1cc2NC(=O)CC(c3cccc(Cl)c3Cl)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B14 compound treatment 744095.0 281000.0 0.58 709384.0 246000.0 0.53 0.7871 0.9991 1657525 ChemDiv1_023972 CCC1(CN2CC3(CC)CN(C1)C2c4cccc(C)c4)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B15 compound treatment 767651.0 304000.0 0.63 731661.0 269000.0 0.58 0.8556 0.9993 1521648 ChemDiv1_023973 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN2CCCC2)c3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B16 compound treatment 735547.0 272000.0 0.56 714611.0 252000.0 0.54 0.7827 0.9999 1682710 ChemDiv1_023974 CC(Cc1ccccc1)NC(=O)C2(CCOCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B17 compound treatment 778004.0 315000.0 0.65 726631.0 264000.0 0.57 0.863 0.9979 1980886 ChemDiv1_023975 Cc1cccc(c1)C2=Nc3ccccc3N=C(C2)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B18 compound treatment 731950.0 269000.0 0.55 709432.0 247000.0 0.53 0.7695 0.9998 1980887 ChemDiv1_023976 CCC(O)C(C)C1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C4(C)CC(=C(O4)C1C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B19 compound treatment 739657.0 276000.0 0.57 703961.0 241000.0 0.52 0.7724 0.999 1980888 ChemDiv1_023977 Cc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B20 compound treatment 714923.0 252000.0 0.52 683040.0 220000.0 0.48 0.7042 0.9991 1980889 ChemDiv1_023978 O=C1N(C2CC2)C(Sc3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B21 compound treatment 730769.0 267000.0 0.55 692411.0 230000.0 0.5 0.7417 0.9986 1980890 ChemDiv1_023979 Cc1ccc(C2=Nc3ccccc3N=C(C2)c4ccc(cc4)C(C)(C)C)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B22 compound treatment 700472.0 237000.0 0.49 644892.0 182000.0 0.39 0.6248 0.9942 1980891 ChemDiv1_023980 CO[C@H]1[C@H](N(C(C(=O)OCc2ccccc2)C(=O)OCc3ccccc3)C1=O)C(C)(C)CSc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B23 mock treatment 679415.0 216000.0 0.45 649436.0 187000.0 0.4 0.601 0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 B24 mock treatment 227727.0 -236000.0 -0.49 209140.0 -254000.0 -0.55 -0.7322 -0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C01 compound treatment 620475.0 157000.0 0.32 606172.0 143000.0 0.31 0.4487 0.9997 1598636 ChemDiv1_023981 COc1ccc(cc1)C(=O)N2c3cc(Cl)ccc3-c4c(ssc4=S)C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C02 compound treatment 676253.0 213000.0 0.44 648231.0 185000.0 0.4 0.5945 0.999 1443506 ChemDiv1_023982 COc1ccc(CC(=O)NCC2(CCCC2)c3ccccc3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C03 compound treatment 705753.0 242000.0 0.5 711104.0 248000.0 0.54 0.7338 0.9994 1980892 ChemDiv1_023983 [O-][N+](=O)c1ccc(NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C04 compound treatment 690068.0 227000.0 0.47 684975.0 222000.0 0.48 0.6709 0.9999 1547464 ChemDiv1_023984 Cc1cc2NC(=O)CC(c3ccccc3Cl)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C05 compound treatment 712069.0 249000.0 0.51 680709.0 218000.0 0.47 0.6965 0.9991 1786036 ChemDiv1_023985 [O-][N+](=O)c1ccc2OC3(CCCCC3=Cc2c1)N4CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C06 compound treatment 716208.0 253000.0 0.52 700701.0 238000.0 0.51 0.7331 1.0 1239248 ChemDiv1_023986 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(Br)ccc1c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C07 compound treatment 731683.0 268000.0 0.55 726867.0 264000.0 0.57 0.7958 0.9999 1980893 ChemDiv1_023987 Cc1ccc(cc1)N2C3N(c4ccccc4C2N(c5ccccc35)S(=O)(=O)c6ccc(C)cc6)S(=O)(=O)c7ccc(C)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C08 compound treatment 758761.0 295000.0 0.61 737318.0 274000.0 0.59 0.8513 0.9999 1402327 ChemDiv1_023988 CCn1cnc2sc(C(=O)N3CCN(Cc4ccccc4)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C09 compound treatment 745232.0 282000.0 0.58 746812.0 284000.0 0.61 0.8461 0.9996 1722779 ChemDiv1_023989 Cc1nc2oc3c(ncnc3c2c4CC(C)(C)OCc14)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C10 compound treatment 759508.0 296000.0 0.61 714849.0 252000.0 0.55 0.818 0.9984 1209536 ChemDiv1_023990 Brc1ccc(cc1)N2C(=O)c3sc4nnc(c5ccccc5)c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C11 compound treatment 742074.0 279000.0 0.58 742166.0 279000.0 0.6 0.8344 0.9997 1980894 ChemDiv1_023991 CCOC(=O)C1=NNC2(C1C(=O)N(C2=O)c3cccc(Br)c3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C12 compound treatment 754525.0 291000.0 0.6 719641.0 257000.0 0.56 0.8181 0.9992 1559694 ChemDiv1_023992 COc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)NCCc4ccccc4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C13 compound treatment 776671.0 313000.0 0.65 706022.0 243000.0 0.53 0.8295 0.9947 1509050 ChemDiv1_023993 Cc1ccc(cc1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C14 compound treatment 765483.0 302000.0 0.62 747831.0 285000.0 0.62 0.8772 1.0 1495945 ChemDiv1_023994 Clc1ccc(cc1)S(=O)(=O)NC2C(N3CCN(CC3)C(=S)Nc4ccccc4)c5cccc6cccc2c56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C15 compound treatment 786795.0 324000.0 0.67 721962.0 259000.0 0.56 0.8687 0.9962 1241199 ChemDiv1_023995 COc1ccc(cc1OC)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C16 compound treatment 758647.0 295000.0 0.61 724770.0 262000.0 0.57 0.8319 0.9993 1195957 ChemDiv1_023996 CCN(CC)C1C(NS(=O)(=O)c2ccccc2)c3cccc4cccc1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C17 compound treatment 754667.0 291000.0 0.6 737876.0 275000.0 0.6 0.8462 1.0 1928481 ChemDiv1_023997 Cc1nn(c(O)c1C(=O)c2ccccc2F)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C18 compound treatment 743074.0 280000.0 0.58 717821.0 255000.0 0.55 0.7986 0.9997 1980895 ChemDiv1_023998 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccccc3OC)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C19 compound treatment 688380.0 225000.0 0.46 677560.0 215000.0 0.46 0.6571 1.0 1037809 ChemDiv1_023999 CC(C)OC1(OC(=O)c2ccccc21)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C20 compound treatment 710497.0 247000.0 0.51 732338.0 269000.0 0.58 0.7732 0.9978 1413705 ChemDiv1_024000 CCCC(CCC)C(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN4CCOCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C21 compound treatment 756293.0 293000.0 0.6 710638.0 248000.0 0.54 0.8069 0.9982 1493420 ChemDiv1_024001 CCN(CC)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C22 compound treatment 699695.0 236000.0 0.49 669262.0 206000.0 0.45 0.6609 0.999 1980896 ChemDiv1_024002 CC(C)Oc1ccc(CNCCC2(CCOC(C)(C)C2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C23 mock treatment 682852.0 220000.0 0.45 678183.0 215000.0 0.47 0.65 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 C24 mock treatment 198993.0 -264000.0 -0.55 224428.0 -238000.0 -0.52 -0.7507 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D01 compound treatment 687258.0 224000.0 0.46 597891.0 135000.0 0.29 0.5335 0.9755 1980897 ChemDiv1_024003 O=C(N1CCCc2ccccc12)C(=O)N3CCCc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D02 compound treatment 649082.0 186000.0 0.38 637656.0 175000.0 0.38 0.5387 1.0 1980898 ChemDiv1_024004 COc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D03 compound treatment 692102.0 229000.0 0.47 667267.0 204000.0 0.44 0.6468 0.9995 1980899 ChemDiv1_024005 COc1ccc(/C=C/C(=O)N2c3cc(C)ccc3C(C)(CC2(C)C)c4ccccc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D04 compound treatment 673042.0 210000.0 0.43 649645.0 187000.0 0.4 0.592 0.9994 1980900 ChemDiv1_024006 FC(F)(F)c1cc(NC(=O)C(=O)NCC=C)ccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D05 compound treatment 715241.0 252000.0 0.52 686514.0 224000.0 0.48 0.71 0.9994 1980901 ChemDiv1_024007 COc1ccc-2c(c1)C(=NNC(=O)c3ccccn3)c4cc(OC)ccc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D06 compound treatment 692620.0 229000.0 0.47 647405.0 184000.0 0.4 0.6171 0.9964 1980902 ChemDiv1_024008 CC(C)CNC(=O)C(=O)Nc1ccc(C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D07 compound treatment 729162.0 266000.0 0.55 697097.0 234000.0 0.51 0.7465 0.9992 1980903 ChemDiv1_024009 Cc1nc2sccn2c(=O)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D08 compound treatment 723944.0 261000.0 0.54 696086.0 233000.0 0.5 0.7374 0.9995 1501993 ChemDiv1_024010 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(OC)c(OC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D09 compound treatment 746229.0 283000.0 0.58 741629.0 279000.0 0.6 0.8396 0.9999 1393560 ChemDiv1_024011 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D10 compound treatment 671926.0 209000.0 0.43 657623.0 195000.0 0.42 0.6026 0.9999 1191484 ChemDiv1_024012 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCC(=O)O)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D11 compound treatment 747721.0 284000.0 0.59 712659.0 250000.0 0.54 0.7974 0.9991 1532069 ChemDiv1_024013 Fc1ccc(cc1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D12 compound treatment 686925.0 224000.0 0.46 683979.0 221000.0 0.48 0.6648 0.9998 1201578 ChemDiv1_024014 Clc1ccc(cc1)C2=Nc3ccccc3N(C(C2)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D13 compound treatment 738820.0 276000.0 0.57 763116.0 300000.0 0.65 0.8617 0.9978 1317512 ChemDiv1_024015 Cc1cc2NC(=O)CC(c3ccc(Cl)cc3Cl)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D14 compound treatment 734679.0 271000.0 0.56 718249.0 255000.0 0.55 0.787 1.0 1296506 ChemDiv1_024016 CCC1(CN2CC3(CC)CN(C1)C2c4ccccc4Cl)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D15 compound treatment 774589.0 311000.0 0.64 732016.0 269000.0 0.58 0.8663 0.9988 1431010 ChemDiv1_024017 Cc1ccc(cc1)N(CC(O)CN2CCCC2)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D16 compound treatment 753406.0 290000.0 0.6 728732.0 266000.0 0.58 0.8303 0.9998 1980904 ChemDiv1_024018 CC(N1CCCC1)C(=O)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D17 compound treatment 779513.0 316000.0 0.65 748207.0 285000.0 0.62 0.8982 0.9996 1980905 ChemDiv1_024019 Oc1ccccc1C2=Nc3ccccc3N=C(C2)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D18 compound treatment 726073.0 263000.0 0.54 682915.0 220000.0 0.48 0.7203 0.9979 1980906 ChemDiv1_024020 CCCCCC(C)C(C)c1cc(OCC(=O)N2CCN(CC2)C3CC3)c4C5=C(CCC5)C(C)(C)Oc4c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D19 compound treatment 750080.0 287000.0 0.59 721395.0 258000.0 0.56 0.8143 0.9996 1980907 ChemDiv1_024021 Cc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D20 compound treatment 712917.0 250000.0 0.52 687121.0 224000.0 0.49 0.7075 0.9995 1100699 ChemDiv1_024022 CN1C(=O)CSC(c2c(C)nn(C)c12)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D21 compound treatment 735110.0 272000.0 0.56 714780.0 252000.0 0.55 0.7823 0.9999 1980908 ChemDiv1_024023 COc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4ccc(C)cc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D22 compound treatment 703064.0 240000.0 0.49 685257.0 222000.0 0.48 0.6903 0.9999 1735631 ChemDiv1_024024 CC1CCN(Cc2cc(O)c(CN3CCC(C)CC3)cc2O)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D23 mock treatment 697162.0 234000.0 0.48 672446.0 210000.0 0.45 0.6621 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 D24 mock treatment 215507.0 -248000.0 -0.51 217224.0 -246000.0 -0.53 -0.7377 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E01 compound treatment 639834.0 177000.0 0.36 611480.0 149000.0 0.32 0.4851 0.9981 1600804 ChemDiv1_024025 CC1(CC(O)CC(N1)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E02 compound treatment 627099.0 164000.0 0.34 605906.0 143000.0 0.31 0.458 0.999 1980909 ChemDiv1_024026 COc1ccc(cc1OC)C2(CNC(=O)C(=O)NC(C)CCc3ccccc3)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E03 compound treatment 685028.0 222000.0 0.46 687571.0 225000.0 0.49 0.6675 0.9995 1980910 ChemDiv1_024027 [O-][N+](=O)c1ccccc1NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E04 compound treatment 585393.0 122000.0 0.25 576566.0 114000.0 0.25 0.3522 0.9999 1980911 ChemDiv1_024028 COc1ccc(cc1)C2=C(Nc3ccc(cc3)C(=O)N)c4ccccc4C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E05 compound treatment 706466.0 243000.0 0.5 675520.0 213000.0 0.46 0.6804 0.9991 1786038 ChemDiv1_024029 [O-][N+](=O)c1ccc2OC3(CCCCC3=Cc2c1)NCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E06 compound treatment 696222.0 233000.0 0.48 699831.0 237000.0 0.51 0.7026 0.9995 1775085 ChemDiv1_024030 OCCN1CCN(CC1)c2nc3c(=O)[nH]cnc3n2C4OC(CO)C(O)C4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E07 compound treatment 743670.0 280000.0 0.58 729444.0 267000.0 0.58 0.8172 1.0 1980912 ChemDiv1_024031 Cc1ccc(cc1)S(=O)(=O)N2C3N(C(N(c4ccccc34)S(=O)(=O)c5ccc(C)cc5)c6ccccc26)c7ccc(SCC(=O)O)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E08 compound treatment 696207.0 233000.0 0.48 729935.0 267000.0 0.58 0.7487 0.9958 1409379 ChemDiv1_024032 Cc1ccccc1n2cc(C(=O)O)c3ccccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E09 compound treatment 762033.0 299000.0 0.62 810559.0 348000.0 0.75 0.9682 0.9951 1471317 ChemDiv1_024033 CC1(C)Cc2c(CO1)c(nc3oc(C(=O)c4ccc(Br)cc4)c(N)c23)c5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E10 compound treatment 695910.0 233000.0 0.48 719996.0 257000.0 0.56 0.733 0.9973 1980913 ChemDiv1_024034 O=C(N/N=C\c1cn(nc1c2cccnc2)c3ccccc3)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E11 compound treatment 717757.0 254000.0 0.53 739425.0 277000.0 0.6 0.7947 0.9979 1567408 ChemDiv1_024035 COc1ccc(cc1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E12 compound treatment 711377.0 248000.0 0.51 717218.0 254000.0 0.55 0.7514 0.9994 1198689 ChemDiv1_024036 COc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)NCCc4ccc(OC)c(OC)c4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E13 compound treatment 720157.0 257000.0 0.53 669721.0 207000.0 0.45 0.6915 0.9964 1980914 ChemDiv1_024037 O=C1N(C(N2CCCN21)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E14 compound treatment 764549.0 301000.0 0.62 695956.0 233000.0 0.5 0.7964 0.9946 1627011 ChemDiv1_024038 C=CCNC(=S)N1CCN(CC1)C2C(NS(=O)(=O)c3ccccc3)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E15 compound treatment 736738.0 273000.0 0.56 756637.0 294000.0 0.64 0.8487 0.9982 1980915 ChemDiv1_024039 COc1cc(/C=C/2\CC(C/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O)C(C)(C)C)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E16 compound treatment 775846.0 313000.0 0.65 740009.0 277000.0 0.6 0.8803 0.9993 1621326 ChemDiv1_024040 CCN(CC)C1C(NS(=O)(=O)c2ccc(Cl)cc2)c3cccc4cccc1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E17 compound treatment 753224.0 290000.0 0.6 741060.0 278000.0 0.6 0.8489 1.0 1939687 ChemDiv1_024041 Cc1nn(c(O)c1C(=O)c2cccc(F)c2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E18 compound treatment 815058.0 352000.0 0.73 841928.0 379000.0 0.82 1.0936 0.9982 1980916 ChemDiv1_024042 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3cc(OC)c(O)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E19 compound treatment 695806.0 233000.0 0.48 669038.0 206000.0 0.45 0.6549 0.9993 1980917 ChemDiv1_024043 CCCCCCCOC1(OC(=O)c2ccccc21)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E20 compound treatment 727601.0 264000.0 0.55 672489.0 210000.0 0.45 0.7066 0.9958 1950283 ChemDiv1_024044 CCCC(CCC)C(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN4CCN(C)CC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E21 compound treatment 693256.0 230000.0 0.47 666893.0 204000.0 0.44 0.6479 0.9993 1476935 ChemDiv1_024045 COc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E22 compound treatment 680219.0 217000.0 0.45 696880.0 234000.0 0.51 0.6748 0.9981 1561221 ChemDiv1_024046 CC(NCCC1(CCOC(C)(C)C1)c2ccc(C)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E23 mock treatment 705233.0 242000.0 0.5 693107.0 230000.0 0.5 0.7055 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 E24 mock treatment 198103.0 -265000.0 -0.55 225549.0 -237000.0 -0.51 -0.7503 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F01 compound treatment 640581.0 177000.0 0.37 588528.0 126000.0 0.27 0.4511 0.9893 1980918 ChemDiv1_024047 O=C(NNc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1Cc5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F02 compound treatment 662971.0 200000.0 0.41 631837.0 169000.0 0.37 0.55 0.9982 1980919 ChemDiv1_024048 COc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F03 compound treatment 701622.0 238000.0 0.49 695795.0 233000.0 0.5 0.7043 0.9999 1378463 ChemDiv1_024049 CC1(C2C(C(=O)N(Cc3ccccc3)C2=O)C4(C)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F04 compound treatment 692579.0 229000.0 0.47 663674.0 201000.0 0.43 0.642 0.9991 1923623 ChemDiv1_024050 OCCCNC(=O)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F05 compound treatment 732777.0 270000.0 0.56 711586.0 249000.0 0.54 0.774 0.9999 1980920 ChemDiv1_024051 CCOc1ccc-2c(c1)C(=NNC(=O)c3ccccn3)c4cc(OCC)ccc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F06 compound treatment 703735.0 240000.0 0.5 667881.0 205000.0 0.44 0.6647 0.9984 1980921 ChemDiv1_024052 COCCCNC(=O)C(=O)Nc1ccc(C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F07 compound treatment 768415.0 305000.0 0.63 722455.0 260000.0 0.56 0.8426 0.9984 1552242 ChemDiv1_024053 OC12NC(=O)N(CC=C)C2(O)c3ccccc3C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F08 compound treatment 696936.0 234000.0 0.48 694529.0 232000.0 0.5 0.6956 0.9998 1419192 ChemDiv1_024054 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC=C)c(Cl)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F09 compound treatment 732627.0 269000.0 0.56 745601.0 283000.0 0.61 0.8258 0.9989 1350871 ChemDiv1_024055 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(C)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F10 compound treatment 650197.0 187000.0 0.39 641672.0 179000.0 0.39 0.5464 1.0 1547141 ChemDiv1_024056 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC(=O)O)c(Cl)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F11 compound treatment 751242.0 288000.0 0.59 725533.0 263000.0 0.57 0.8223 0.9997 1241842 ChemDiv1_024057 CCc1ccc(cc1)N2C(=O)c3sc4nnc(C)c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F12 compound treatment 747008.0 284000.0 0.59 700934.0 238000.0 0.52 0.7785 0.998 1980922 ChemDiv1_024058 Cc1ccc(cc1)C(=O)N2C(CC(=Nc3ccccc23)c4ccc(Cl)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F13 compound treatment 772190.0 309000.0 0.64 697177.0 234000.0 0.51 0.8095 0.9936 1716452 ChemDiv1_024059 Cc1ccc(Cn2c(=O)n(C)c3ncn(C)c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F14 compound treatment 726593.0 263000.0 0.54 725970.0 263000.0 0.57 0.787 0.9997 1980923 ChemDiv1_024060 CC1(C)C2(CN3CC1(CN(C2)C3c4ccccc4Cl)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F15 compound treatment 749206.0 286000.0 0.59 734405.0 271000.0 0.59 0.8329 1.0 1980924 ChemDiv1_024061 OC(CN(c1ccccc1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])CN3CCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F16 compound treatment 734741.0 271000.0 0.56 707274.0 244000.0 0.53 0.7702 0.9996 1271658 ChemDiv1_024062 COc1ccc(cc1OC)C2(CCOCC2)C(=O)NCC3(CCCOC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F17 compound treatment 764077.0 301000.0 0.62 717634.0 255000.0 0.55 0.8289 0.9982 1980925 ChemDiv1_024063 Oc1ccccc1C2=Nc3ccccc3N=C(C2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F18 compound treatment 698914.0 236000.0 0.49 664208.0 201000.0 0.44 0.652 0.9985 1980926 ChemDiv1_024064 CCCCCC(C)C(C)c1cc(OCCCCN2CCOCC2)c3C4=C(CCC4)C(C)(C)Oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F19 compound treatment 735873.0 273000.0 0.56 698555.0 236000.0 0.51 0.7586 0.9988 1980927 ChemDiv1_024065 Cc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F20 compound treatment 715522.0 252000.0 0.52 685719.0 223000.0 0.48 0.7092 0.9993 1303774 ChemDiv1_024066 O=C(OCCN1CCCCC1)C2(CCOc3ccccc32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F21 compound treatment 738893.0 276000.0 0.57 685945.0 223000.0 0.48 0.7437 0.9967 1980928 ChemDiv1_024067 Oc1ccc(Cl)cc1C2=Nc3ccccc3N=C(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F22 compound treatment 721913.0 259000.0 0.53 673093.0 210000.0 0.45 0.6992 0.9968 1283809 ChemDiv1_024068 O=S(=O)(NC1C(N2CCOCC2)c3cccc4cccc1c34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F23 mock treatment 726177.0 263000.0 0.54 698970.0 236000.0 0.51 0.745 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 F24 mock treatment 213747.0 -250000.0 -0.52 215266.0 -248000.0 -0.54 -0.7432 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G01 compound treatment 616672.0 153000.0 0.32 570314.0 107000.0 0.23 0.3883 0.9885 1980929 ChemDiv1_024069 CCCCCCC1(O)C(C)C(NC(C1C)c2ccc(cc2)N(C)C)c3ccc(cc3)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G02 compound treatment 629069.0 166000.0 0.34 652862.0 190000.0 0.41 0.5327 0.9958 1980930 ChemDiv1_024070 CNC(=O)C(=O)NCC1(CCCC1)c2ccc(OC)c(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G03 compound treatment 666176.0 203000.0 0.42 689000.0 226000.0 0.49 0.6422 0.997 1615693 ChemDiv1_024071 CC(C)(C)NC(=O)CSc1nnc2-c3cccc4cccc(-c2n1)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G04 compound treatment 652315.0 189000.0 0.39 678211.0 215000.0 0.47 0.6055 0.9961 1010737 ChemDiv1_024072 CC1CC2(CC(C)OC2=O)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G05 compound treatment 695569.0 232000.0 0.48 683384.0 220000.0 0.48 0.6765 1.0 1786039 ChemDiv1_024073 [O-][N+](=O)c1ccc2OC3(CCCCC3=Cc2c1)NC4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G06 compound treatment 763726.0 300000.0 0.62 792989.0 330000.0 0.71 0.9437 0.9975 1980931 ChemDiv1_024074 O=C(CN1C=C(Cc2ccccc12)c3ccc4ccccc4n3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G07 compound treatment 726642.0 263000.0 0.54 685520.0 223000.0 0.48 0.7251 0.9982 1980932 ChemDiv1_024075 [O-][N+](=O)c1ccc2O/C(=C/COc3ccc(F)cc3)/C(N4CCOCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G08 compound treatment 724912.0 262000.0 0.54 732911.0 270000.0 0.58 0.7951 0.9992 1980933 ChemDiv1_024076 CCOc1ccc(cc1)n2cc(C(=O)O)c3cc(OC)c(OC)cc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G09 compound treatment 744266.0 281000.0 0.58 754673.0 292000.0 0.63 0.8567 0.9991 1604791 ChemDiv1_024077 CC1(C)Cc2c(CO1)c(nc3oc(C(=O)c4ccc(Br)cc4)c(N)c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G10 compound treatment 679927.0 217000.0 0.45 703264.0 240000.0 0.52 0.6841 0.9972 1980934 ChemDiv1_024078 COc1ccc(cc1)c2nn(cc2/C=N\NC(=O)c3ccncc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G11 compound treatment 739352.0 276000.0 0.57 728211.0 265000.0 0.57 0.809 1.0 1685212 ChemDiv1_024079 COc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G12 compound treatment 702164.0 239000.0 0.49 697999.0 235000.0 0.51 0.7085 0.9999 1374074 ChemDiv1_024080 COc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)N4CCN(CCO)CC4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G13 compound treatment 748294.0 285000.0 0.59 714220.0 251000.0 0.54 0.8007 0.9992 1942332 ChemDiv1_024081 Cc1ccc(cc1)C2N(C(=O)N3CCCN23)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G14 compound treatment 764181.0 301000.0 0.62 700711.0 238000.0 0.51 0.8032 0.9956 1512137 ChemDiv1_024082 Clc1ccc(cc1)S(=O)(=O)NC2C(N3CCN(CC3)C(=S)NCC=C)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G15 compound treatment 774956.0 312000.0 0.64 723531.0 261000.0 0.56 0.8538 0.9978 1126451 ChemDiv1_024083 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccccn4)ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G16 compound treatment 738656.0 275000.0 0.57 726385.0 263000.0 0.57 0.8052 1.0 1497594 ChemDiv1_024084 COc1ccc(NC2C(NS(=O)(=O)c3ccccc3)c4cccc5cccc2c45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G17 compound treatment 758923.0 296000.0 0.61 756346.0 293000.0 0.64 0.8806 0.9998 1980935 ChemDiv1_024085 Cc1nn(c(O)c1C(=O)c2ccc(Cl)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G18 compound treatment 704826.0 242000.0 0.5 680483.0 218000.0 0.47 0.6856 0.9996 1980936 ChemDiv1_024086 CCOC(=O)C1=C(Nc2cccc(Cl)c2)S/C(=C/c3cc(OC)c(OC)c(OC)c3)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G19 compound treatment 690286.0 227000.0 0.47 687478.0 225000.0 0.49 0.6751 0.9998 1733080 ChemDiv1_024087 CCCCC(CC)COC1(OC(=O)c2ccccc21)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G20 compound treatment 723055.0 260000.0 0.54 690948.0 228000.0 0.49 0.7282 0.9991 1980937 ChemDiv1_024088 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)C=C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G21 compound treatment 719132.0 256000.0 0.53 682398.0 219000.0 0.48 0.7094 0.9986 1580890 ChemDiv1_024089 CCN(CC)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G22 compound treatment 658148.0 195000.0 0.4 645362.0 182000.0 0.39 0.5637 1.0 1683956 ChemDiv1_024090 CCC(=O)N(CCC1(CCOC(C)(C)C1)c2ccccc2)Cc3ccc(OC(C)C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G23 mock treatment 680267.0 217000.0 0.45 715432.0 253000.0 0.55 0.7032 0.9951 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 G24 mock treatment 212627.0 -251000.0 -0.52 237214.0 -226000.0 -0.49 -0.7113 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H01 compound treatment 633222.0 170000.0 0.35 583073.0 120000.0 0.26 0.432 0.9891 1980938 ChemDiv1_024091 CCC(C)C(=O)N1c2c(C)cc(C)cc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H02 compound treatment 646170.0 183000.0 0.38 610984.0 148000.0 0.32 0.4936 0.9967 1980939 ChemDiv1_024092 COc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H03 compound treatment 671978.0 209000.0 0.43 671516.0 209000.0 0.45 0.6239 0.9997 1308180 ChemDiv1_024093 CC1(C2C(C3c4ccccc41)C(=O)N(Cc5ccccc5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H04 compound treatment 658727.0 195000.0 0.4 648829.0 186000.0 0.4 0.5698 1.0 1939998 ChemDiv1_024094 CCCN(CCC)CCCNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H05 compound treatment 675714.0 212000.0 0.44 692227.0 229000.0 0.5 0.6611 0.9981 1484957 ChemDiv1_024095 CC(=O)Nc1ccccc1N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H06 compound treatment 643383.0 180000.0 0.37 658614.0 196000.0 0.42 0.5624 0.9979 1980940 ChemDiv1_024096 COCCCNC(=O)C(=O)Nc1ccc(C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H07 compound treatment 694014.0 231000.0 0.48 644164.0 181000.0 0.39 0.6142 0.9954 1662104 ChemDiv1_024097 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H08 compound treatment 676055.0 213000.0 0.44 670345.0 207000.0 0.45 0.6281 0.9999 1327388 ChemDiv1_024098 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(OC)c(OCC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H09 compound treatment 696158.0 233000.0 0.48 720603.0 258000.0 0.56 0.7343 0.9973 1724399 ChemDiv1_024099 Clc1ccc(cc1)N2C(=O)c3sc4nc5CCCc5c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H10 compound treatment 662262.0 199000.0 0.41 657009.0 194000.0 0.42 0.5875 0.9999 1358079 ChemDiv1_024100 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)c(OC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H11 compound treatment 730880.0 268000.0 0.55 703597.0 241000.0 0.52 0.759 0.9996 1205506 ChemDiv1_024101 Cc1nnc2sc3C(=O)N(C(=O)c3n2c1=O)c4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H12 compound treatment 734076.0 271000.0 0.56 669995.0 207000.0 0.45 0.7122 0.994 1175082 ChemDiv1_024102 COc1ccc(cc1)C(=O)N2C(CC(=Nc3ccccc23)c4ccc(C)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H13 compound treatment 695163.0 232000.0 0.48 714299.0 251000.0 0.54 0.7232 0.998 1980941 ChemDiv1_024103 CCCN(CCC)CC(O)CN(c1ccccc1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H14 compound treatment 727837.0 265000.0 0.55 663833.0 201000.0 0.43 0.6937 0.9936 1421153 ChemDiv1_024104 Cc1ccccc1C2N3CC4(C)CN2CC(C)(C3)C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H15 compound treatment 718891.0 256000.0 0.53 721606.0 259000.0 0.56 0.769 0.9996 1437288 ChemDiv1_024105 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN2CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H16 compound treatment 729410.0 266000.0 0.55 681574.0 219000.0 0.47 0.7231 0.9972 1980942 ChemDiv1_024106 COc1cccc(c2nc(c([nH]2)c3cc(ccc3OC)[N+](=O)[O-])c4ccccc4)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H17 compound treatment 766755.0 303000.0 0.63 710382.0 247000.0 0.54 0.8217 0.997 1980943 ChemDiv1_024107 Oc1ccccc1C2=Nc3ccccc3N=C(C2)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H18 compound treatment 695765.0 232000.0 0.48 666176.0 203000.0 0.44 0.6505 0.9991 1679966 ChemDiv1_024108 CC(CCc1ccc(F)cc1)c2cc(O)c3C4=C(CCN(CC#C)C4)C(C)(C)Oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H19 compound treatment 737966.0 275000.0 0.57 699537.0 237000.0 0.51 0.7631 0.9987 1980944 ChemDiv1_024109 COc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4cc(C)ccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H20 compound treatment 739147.0 276000.0 0.57 696403.0 233000.0 0.51 0.76 0.9982 1980945 ChemDiv1_024110 O=C1NC(Sc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H21 compound treatment 782795.0 320000.0 0.66 686808.0 224000.0 0.48 0.8091 0.9885 1980946 ChemDiv1_024111 Oc1ccc(Cl)cc1C2=Nc3ccccc3N=C(C2)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H22 compound treatment 710754.0 247000.0 0.51 682065.0 219000.0 0.47 0.6967 0.9993 1558789 ChemDiv1_024112 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3ccc(I)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H23 mock treatment 687983.0 225000.0 0.46 670941.0 208000.0 0.45 0.6464 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 H24 mock treatment 206763.0 -257000.0 -0.53 253906.0 -209000.0 -0.45 -0.6943 -0.9969 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I01 compound treatment 656129.0 193000.0 0.4 634592.0 172000.0 0.37 0.5443 0.9994 1980947 ChemDiv1_024113 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3OC)nc2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I02 compound treatment 636697.0 173000.0 0.36 642313.0 179000.0 0.39 0.5277 0.9992 1701470 ChemDiv1_024114 COc1cc2C(=NCC3(CCCC3)c2cc1OC)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I03 compound treatment 694618.0 231000.0 0.48 691760.0 229000.0 0.5 0.6879 0.9998 1211173 ChemDiv1_024115 O=C(CSc1nnc2-c3cccc4cccc(-c2n1)c34)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I04 compound treatment 664432.0 201000.0 0.42 674721.0 212000.0 0.46 0.6178 0.9988 1674077 ChemDiv1_024116 C[N+]1(C)CCc2cc3OCOc3c4-c5ccccc5CC1c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I05 compound treatment 692396.0 229000.0 0.47 714939.0 252000.0 0.55 0.7202 0.9975 1980948 ChemDiv1_024117 Cc1[nH]c2ccccc2c1C3C4CCCCC4(Oc5ccc(cc35)[N+](=O)[O-])N6CCOCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I06 compound treatment 800627.0 337000.0 0.7 815167.0 352000.0 0.76 1.0315 0.999 1980949 ChemDiv1_024118 C=CCN1C=C(C(C#N)c2ccccc12)c3ccc4ccccc4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I07 compound treatment 726539.0 263000.0 0.54 716212.0 253000.0 0.55 0.772 1.0 1786035 ChemDiv1_024119 CC(C)(O)/C=C\1/Oc2ccccc2C1N3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I08 compound treatment 697923.0 235000.0 0.48 706244.0 243000.0 0.53 0.7149 0.9991 1121450 ChemDiv1_024120 CN1CCN(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I09 compound treatment 713528.0 250000.0 0.52 717016.0 254000.0 0.55 0.7542 0.9995 1980950 ChemDiv1_024121 CC1(C)Cc2c(CO1)c(nc3oc4c(ncnc4c23)c5ccc(Br)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I10 compound treatment 697424.0 234000.0 0.48 742754.0 280000.0 0.61 0.7701 0.9937 1980951 ChemDiv1_024122 COc1ccc(cc1OC)c2nn(cc2/C=N\NC(=O)c3ccncc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I11 compound treatment 735250.0 272000.0 0.56 703244.0 240000.0 0.52 0.7648 0.9993 1537787 ChemDiv1_024123 Cc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I12 compound treatment 723163.0 260000.0 0.54 715119.0 252000.0 0.55 0.7654 1.0 1682852 ChemDiv1_024124 O=S(=O)(NC1C(N2CCNCC2)c3cccc4cccc1c34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I13 compound treatment 723450.0 260000.0 0.54 701225.0 238000.0 0.52 0.7445 0.9998 1980952 ChemDiv1_024125 CC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(c5)C(F)(F)F)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I14 compound treatment 746829.0 284000.0 0.59 727661.0 265000.0 0.57 0.8191 0.9999 1680978 ChemDiv1_024126 O=S(=O)(NC1C(NCc2ccco2)c3cccc4cccc1c34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I15 compound treatment 760106.0 297000.0 0.61 730924.0 268000.0 0.58 0.8435 0.9996 1340927 ChemDiv1_024127 COc1cc(cc(OC)c1OC)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I16 compound treatment 726456.0 263000.0 0.54 721466.0 259000.0 0.56 0.7799 0.9999 1695810 ChemDiv1_024128 COc1ccc(NC2C(NS(=O)(=O)c3ccc(Cl)cc3)c4cccc5cccc2c45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I17 compound treatment 775578.0 312000.0 0.64 722049.0 259000.0 0.56 0.8525 0.9976 1980953 ChemDiv1_024129 Cc1nn(c(O)c1C(=O)c2cccc(Br)c2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I18 compound treatment 697454.0 234000.0 0.48 680517.0 218000.0 0.47 0.6749 0.9999 1980954 ChemDiv1_024130 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(Cc5cccc(c5)C(F)(F)F)c6ccccc46)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I19 compound treatment 705485.0 242000.0 0.5 702650.0 240000.0 0.52 0.7205 0.9998 1021340 ChemDiv1_024131 O=C1OC(Oc2ccccc2)(c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I20 compound treatment 708656.0 245000.0 0.51 702835.0 240000.0 0.52 0.7254 0.9999 1980955 ChemDiv1_024132 COC(=O)N1c2ccccc2C=Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I21 compound treatment 721961.0 259000.0 0.53 700843.0 238000.0 0.51 0.7418 0.9998 1189018 ChemDiv1_024133 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(O)c(O)c4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I22 compound treatment 640607.0 177000.0 0.37 632570.0 170000.0 0.37 0.5185 1.0 1980956 ChemDiv1_024134 Cc1ccc(cc1)C2(CC(=O)OCCCC(C#N)c3ccccc3)CCOC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I23 mock treatment 690642.0 227000.0 0.47 687096.0 224000.0 0.49 0.675 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 I24 mock treatment 209244.0 -254000.0 -0.52 227528.0 -235000.0 -0.51 -0.731 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J01 compound treatment 661795.0 199000.0 0.41 619798.0 157000.0 0.34 0.5299 0.9956 1980957 ChemDiv1_024135 CCN(CC)c1ccc(N=c2ssc3c2-c4cc(C)ccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J02 compound treatment 662112.0 199000.0 0.41 647697.0 185000.0 0.4 0.5731 0.9999 1980958 ChemDiv1_024136 COc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4cc(OC)ccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J03 compound treatment 703874.0 241000.0 0.5 678626.0 216000.0 0.47 0.6813 0.9995 1980959 ChemDiv1_024137 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J04 compound treatment 674336.0 211000.0 0.44 657045.0 194000.0 0.42 0.6052 0.9998 1923326 ChemDiv1_024138 Cc1ccc(NC(=O)C(=O)NCCCO)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J05 compound treatment 698075.0 235000.0 0.48 698166.0 235000.0 0.51 0.7028 0.9997 1574182 ChemDiv1_024139 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J06 compound treatment 663952.0 201000.0 0.41 698808.0 236000.0 0.51 0.654 0.9946 1980960 ChemDiv1_024140 COCCCNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J07 compound treatment 718147.0 255000.0 0.53 711287.0 248000.0 0.54 0.7522 0.9999 1624698 ChemDiv1_024141 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J08 compound treatment 703449.0 240000.0 0.5 702905.0 240000.0 0.52 0.7179 0.9997 1261863 ChemDiv1_024142 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCc4cccc(F)c4)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J09 compound treatment 739216.0 276000.0 0.57 712785.0 250000.0 0.54 0.7852 0.9997 1674579 ChemDiv1_024143 O=C1N(C(=O)c2c1sc3nnc(c4ccccc4)c(=O)n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J10 compound treatment 706099.0 243000.0 0.5 660313.0 197000.0 0.43 0.6566 0.9968 1124734 ChemDiv1_024144 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCc4ccc(F)cc4)C(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J11 compound treatment 737910.0 275000.0 0.57 705558.0 243000.0 0.53 0.7722 0.9993 1337080 ChemDiv1_024145 CC(C)(C)C(=O)Nc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J12 compound treatment 744685.0 281000.0 0.58 699659.0 237000.0 0.51 0.7731 0.998 1980961 ChemDiv1_024146 Fc1ccc(cc1)C2=CC(c3ccc(Cl)cc3)n4c(N2)nc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J13 compound treatment 746540.0 283000.0 0.58 776958.0 314000.0 0.68 0.8941 0.9972 1980962 ChemDiv1_024147 CCCN(CCC)CC(O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J14 compound treatment 736507.0 273000.0 0.56 689290.0 226000.0 0.49 0.7453 0.9975 1459487 ChemDiv1_024148 CC1(CN2CC3(C)CN(C1)C2c4ccc(OCC=C)cc4)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J15 compound treatment 752255.0 289000.0 0.6 722854.0 260000.0 0.56 0.8197 0.9996 1335744 ChemDiv1_024149 Cc1ccc(cc1)N(CC(O)CN2CCCC2)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J16 compound treatment 734847.0 272000.0 0.56 709045.0 246000.0 0.53 0.7731 0.9997 1980963 ChemDiv1_024150 COc1ccc(cc1c2[nH]c(nc2c3ccccc3)c4cc(OC)c(OC)cc4OC)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J17 compound treatment 754131.0 291000.0 0.6 727009.0 264000.0 0.57 0.8288 0.9997 1980964 ChemDiv1_024151 CC(C)(C)c1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J18 compound treatment 736985.0 274000.0 0.57 724552.0 262000.0 0.57 0.8 1.0 1980965 ChemDiv1_024152 OC(=O)c1cn(c2ccc(F)cc2)c3cc(N4CCN(CC(F)(F)F)CC4)c(F)cc3c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J19 compound treatment 761455.0 298000.0 0.62 695224.0 232000.0 0.5 0.7908 0.995 1980966 ChemDiv1_024153 Cc1ccc(C2=Nc3ccccc3N=C(C2)c4ccccc4)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J20 compound treatment 709212.0 246000.0 0.51 685822.0 223000.0 0.48 0.7002 0.9997 1980967 ChemDiv1_024154 Clc1ccc(cc1Cl)C2NC(=O)c3ccccc3S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J21 compound treatment 764459.0 301000.0 0.62 722330.0 259000.0 0.56 0.8367 0.9987 1980968 ChemDiv1_024155 Oc1ccc(Cl)cc1C2=Nc3ccccc3N=C(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J22 compound treatment 727113.0 264000.0 0.54 704666.0 242000.0 0.52 0.7551 0.9998 1564905 ChemDiv1_024156 CCc1ccc(cc1)S(=O)(=O)N2CCSC2c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J23 mock treatment 723482.0 260000.0 0.54 693236.0 230000.0 0.5 0.7323 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 J24 mock treatment 200773.0 -263000.0 -0.54 226565.0 -236000.0 -0.51 -0.7449 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K01 compound treatment 652126.0 189000.0 0.39 611526.0 149000.0 0.32 0.5031 0.9954 1662605 ChemDiv1_024157 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(C)c3C)nc2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K02 compound treatment 644578.0 181000.0 0.37 663195.0 200000.0 0.43 0.5712 0.9973 1980969 ChemDiv1_024158 COc1ccc(cc1OC)C2(CNCC(=O)N)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K03 compound treatment 665348.0 202000.0 0.42 680104.0 217000.0 0.47 0.6274 0.9982 1980970 ChemDiv1_024159 Clc1ccccc1CSc2nnc3-c4cccc5cccc(-c3n2)c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K04 compound treatment 646928.0 184000.0 0.38 685189.0 222000.0 0.48 0.6083 0.993 1448255 ChemDiv1_024160 CC(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K05 compound treatment 668390.0 205000.0 0.42 675510.0 213000.0 0.46 0.6248 0.9991 1640263 ChemDiv1_024161 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(C#Cc3ccccc3)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K06 compound treatment 700304.0 237000.0 0.49 697263.0 234000.0 0.51 0.7047 0.9998 1980971 ChemDiv1_024162 [O-][N+](=O)c1ccc(cc1)C(=O)CN2C=C(C(C#N)c3ccccc23)c4ccc5ccccc5n4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K07 compound treatment 713881.0 251000.0 0.52 701266.0 238000.0 0.52 0.7306 1.0 1980972 ChemDiv1_024163 CC(C)(O)/C=C\1/Oc2ccc(cc2C1N3CCOCC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K08 compound treatment 665628.0 202000.0 0.42 689817.0 227000.0 0.49 0.6426 0.9968 1671328 ChemDiv1_024164 CCC(CO)NCC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K09 compound treatment 747616.0 284000.0 0.59 710591.0 248000.0 0.54 0.7941 0.999 1730439 ChemDiv1_024165 CC1(C)Cc2c(CO1)c(nc3oc(C(=O)c4ccccc4)c(N)c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K10 compound treatment 691572.0 228000.0 0.47 681795.0 219000.0 0.47 0.6682 1.0 1980973 ChemDiv1_024166 Fc1ccc(cc1)c2nn(cc2/C=N\NC(=O)c3ccncc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K11 compound treatment 720189.0 257000.0 0.53 713565.0 251000.0 0.54 0.7586 0.9999 1190760 ChemDiv1_024167 COc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K12 compound treatment 684571.0 221000.0 0.46 680542.0 218000.0 0.47 0.6561 0.9999 1643188 ChemDiv1_024168 Clc1ccc(cc1)S(=O)(=O)NC2C(N3CCNCC3)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K13 compound treatment 734703.0 271000.0 0.56 683795.0 221000.0 0.48 0.7343 0.9969 1682270 ChemDiv1_024169 OC(=O)C1C(C2c3ccccc3C1c4ccccc24)C(=O)NCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K14 compound treatment 666898.0 204000.0 0.42 695329.0 232000.0 0.5 0.6529 0.996 1371288 ChemDiv1_024170 Clc1ccc(cc1)S(=O)(=O)NC2C(NCc3ccco3)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K15 compound treatment 743647.0 280000.0 0.58 711655.0 249000.0 0.54 0.79 0.9993 1691763 ChemDiv1_024171 COc1ccc(OC)c(c1)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K16 compound treatment 730094.0 267000.0 0.55 710811.0 248000.0 0.54 0.7689 0.9999 1170355 ChemDiv1_024172 OCCN1CCN(CC1)C2C(NS(=O)(=O)c3ccc(Cl)cc3)c4cccc5cccc2c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K17 compound treatment 750150.0 287000.0 0.59 705289.0 242000.0 0.52 0.7897 0.9982 1980974 ChemDiv1_024173 OC1(C2CCCCC2=NN1C(=O)COc3ccccc3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K18 compound treatment 628426.0 165000.0 0.34 675539.0 213000.0 0.46 0.5665 0.9891 1249778 ChemDiv1_024174 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K19 compound treatment 683907.0 221000.0 0.46 654638.0 192000.0 0.41 0.6155 0.9989 1413848 ChemDiv1_024175 Cc1cccc(C)c1OC2(OC(=O)c3ccccc32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K20 compound treatment 714341.0 251000.0 0.52 701867.0 239000.0 0.52 0.7322 1.0 1376370 ChemDiv1_024176 CC(=O)OCC1OC(C(OC(=O)C)C(OC(=O)C)C1OC(=O)C)n2cnc3[nH]ncc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K21 compound treatment 677926.0 215000.0 0.44 703756.0 241000.0 0.52 0.6819 0.9967 1708687 ChemDiv1_024177 COc1ccc(cc1OC)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K22 compound treatment 679166.0 216000.0 0.45 654780.0 192000.0 0.42 0.6088 0.9994 1211898 ChemDiv1_024178 COc1ccc(cc1)C2(CCNC(C)c3ccccc3)CCOC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K23 mock treatment 669898.0 207000.0 0.43 675127.0 212000.0 0.46 0.6264 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 K24 mock treatment 222439.0 -241000.0 -0.5 227675.0 -235000.0 -0.51 -0.7116 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L01 compound treatment 657587.0 194000.0 0.4 587264.0 124000.0 0.27 0.474 0.9812 1381501 ChemDiv1_024179 COc1cccc(c1)C(=O)N2c3ccc(Cl)cc3-c4c(ssc4=S)C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L02 compound treatment 675553.0 212000.0 0.44 609187.0 146000.0 0.32 0.5337 0.9873 1130 ChemDiv1_024180 OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L03 compound treatment 679908.0 217000.0 0.45 696337.0 233000.0 0.51 0.6735 0.9981 1980975 ChemDiv1_024181 O=C/1NN(C(=O)\C1=C/C=C/c2ccco2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L04 compound treatment 692649.0 229000.0 0.47 674330.0 211000.0 0.46 0.6584 0.9999 1980976 ChemDiv1_024182 CCNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L05 compound treatment 707808.0 245000.0 0.5 655871.0 193000.0 0.42 0.6523 0.9956 1980977 ChemDiv1_024183 CCNCCC(=O)N1c2ccccc2Sc3ccc(cc13)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L06 compound treatment 682781.0 220000.0 0.45 677055.0 214000.0 0.46 0.6482 0.9999 1980978 ChemDiv1_024184 Clc1ccc(NC(=O)C(=O)NCC2CCCO2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L07 compound treatment 689314.0 226000.0 0.47 708743.0 246000.0 0.53 0.7062 0.9979 1166381 ChemDiv1_024185 OC12OC34CCCCC4CC51CCCC2CC6CCCCC65O3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L08 compound treatment 685101.0 222000.0 0.46 662494.0 200000.0 0.43 0.6293 0.9996 1568118 ChemDiv1_024186 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(OC)c(OCC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L09 compound treatment 738378.0 275000.0 0.57 694883.0 232000.0 0.5 0.7566 0.9981 1401307 ChemDiv1_024187 Cc1cccc(N2C(=O)c3sc4nnc(c5ccccc5)c(=O)n4c3C2=O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L10 compound treatment 752408.0 289000.0 0.6 676694.0 214000.0 0.46 0.7492 0.9921 1227503 ChemDiv1_024188 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3OCC)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L11 compound treatment 742103.0 279000.0 0.58 727612.0 265000.0 0.57 0.8121 1.0 1143365 ChemDiv1_024189 Cc1ccc(cc1)C(=O)Nc2ncnc3oc(c(c4ccccc4)c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L12 compound treatment 725774.0 262000.0 0.54 702179.0 239000.0 0.52 0.7494 0.9997 1584058 ChemDiv1_024190 C1CCC2=C(C1)Nc3nc4ccccc4n3C2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L13 compound treatment 707206.0 244000.0 0.5 701337.0 238000.0 0.52 0.721 0.9999 1980979 ChemDiv1_024191 CCCN(CCC)CC(O)CN(c1cccc(C)c1)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L14 compound treatment 703049.0 240000.0 0.49 675771.0 213000.0 0.46 0.6758 0.9994 1219275 ChemDiv1_024192 Cc1ccccc1C2N3CC4(C)CN2CC(C)(C3)C4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L15 compound treatment 732611.0 269000.0 0.56 732594.0 270000.0 0.58 0.8059 0.9997 1279562 ChemDiv1_024193 Cc1ccc(cc1)S(=O)(=O)N(CC(O)CN2CCCC2)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L16 compound treatment 708973.0 246000.0 0.51 686446.0 224000.0 0.48 0.7008 0.9997 1980980 ChemDiv1_024194 COc1ccc(cc1c2[nH]c(nc2c3ccccc3)c4cccs4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L17 compound treatment 734026.0 271000.0 0.56 707382.0 244000.0 0.53 0.7694 0.9996 1980981 ChemDiv1_024195 Cc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L18 compound treatment 708645.0 245000.0 0.51 684809.0 222000.0 0.48 0.6978 0.9996 1045505 ChemDiv1_024196 COc1cc2CCN(C)C3Cc4ccc(O)c(Oc5cc6C(Cc7ccc(Oc(c1O)c32)cc7)N(C)CCc6cc5OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L19 compound treatment 741652.0 278000.0 0.57 710047.0 247000.0 0.53 0.7846 0.9994 1980982 ChemDiv1_024197 Cc1cccc(c1)C2=Nc3ccccc3N=C(C2)c4ccc(C)cc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L20 compound treatment 745635.0 282000.0 0.58 706073.0 243000.0 0.53 0.7843 0.9987 1715827 ChemDiv1_024198 CC(C)(C)c1ccc(O)c(CN2CCCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L21 compound treatment 732427.0 269000.0 0.56 737070.0 274000.0 0.59 0.8125 0.9995 1980983 ChemDiv1_024199 Oc1ccc(Cl)cc1C2=Nc3ccccc3N=C(C2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L22 compound treatment 702216.0 239000.0 0.49 699350.0 236000.0 0.51 0.7106 0.9998 1980984 ChemDiv1_024200 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L23 mock treatment 699081.0 236000.0 0.49 695294.0 232000.0 0.5 0.6999 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 L24 mock treatment 214836.0 -248000.0 -0.51 245497.0 -217000.0 -0.47 -0.6954 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M01 compound treatment 646161.0 183000.0 0.38 594265.0 131000.0 0.28 0.468 0.9902 1980985 ChemDiv1_024201 COc1ccccc1NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M02 compound treatment 627168.0 164000.0 0.34 649647.0 187000.0 0.4 0.525 0.9961 1236360 ChemDiv1_024202 O=C(N1CCOCC1)C2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M03 compound treatment 659677.0 196000.0 0.41 681574.0 219000.0 0.47 0.6213 0.997 1517005 ChemDiv1_024203 COc1cc(cc(OC)c1OC)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M04 compound treatment 677346.0 214000.0 0.44 644590.0 182000.0 0.39 0.5905 0.9983 1467488 ChemDiv1_024204 OC1=C(C(N(C1=O)c2nncs2)c3ccc(F)cc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M05 compound treatment 667761.0 204000.0 0.42 654039.0 191000.0 0.41 0.591 0.9999 1980986 ChemDiv1_024205 OC1(CCCCC1)/C=C/2\Oc3ccc(cc3C2N4CCOCC4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M06 compound treatment 641775.0 179000.0 0.37 643027.0 180000.0 0.39 0.5362 0.9996 1980987 ChemDiv1_024206 CC(C)N(C(=O)CO[C@H]1[C@H](O[C@@H]2OC(C)(C)O[C@H]12)C3COC(C)(C)O3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M07 compound treatment 705376.0 242000.0 0.5 662739.0 200000.0 0.43 0.6592 0.9974 1980988 ChemDiv1_024207 CC(C)C(=O)C1=Cc2cccc([N+](=O)[O-])c2OC1N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M08 compound treatment 690034.0 227000.0 0.47 705990.0 243000.0 0.53 0.703 0.9983 1130598 ChemDiv1_024208 Cc1ccc(cc1)N2C(=O)c3sc4nc5CCCc5c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M09 compound treatment 923750.0 460000.0 0.95 1109962.0 647000.0 1.4 1.6624 0.9822 1980989 ChemDiv1_024209 Cc1nc2c(oc3nc(c4ccco4)c5COC(C)(C)Cc5c32)c(c6ccc(Br)cc6)c1C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M10 compound treatment 673244.0 210000.0 0.43 657318.0 194000.0 0.42 0.604 0.9999 1980990 ChemDiv1_024210 O=C(N/N=C\c1cn(nc1c2cccs2)c3ccccc3)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M11 compound treatment 705242.0 242000.0 0.5 698727.0 236000.0 0.51 0.7141 0.9999 1433269 ChemDiv1_024211 Cc1ccc(C)c(c1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M12 compound treatment 670833.0 208000.0 0.43 672310.0 209000.0 0.45 0.6235 0.9996 1131027 ChemDiv1_024212 O=C(N1CCN(CC1)C2C(NS(=O)(=O)c3ccccc3)c4cccc5cccc2c45)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M13 compound treatment 701317.0 238000.0 0.49 705088.0 242000.0 0.52 0.7181 0.9995 1513874 ChemDiv1_024213 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(Cc5ccc(F)cc5)C2=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M14 compound treatment 676429.0 213000.0 0.44 665923.0 203000.0 0.44 0.6218 1.0 1306884 ChemDiv1_024214 CN(C)C1C(NS(=O)(=O)c2ccccc2)c3cccc4cccc1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M15 compound treatment 720759.0 257000.0 0.53 690849.0 228000.0 0.49 0.7247 0.9993 1193240 ChemDiv1_024215 COc1ccccc1C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M16 compound treatment 689250.0 226000.0 0.47 677540.0 215000.0 0.46 0.6583 1.0 1980991 ChemDiv1_024216 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4ccccc4)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M17 compound treatment 706306.0 243000.0 0.5 692574.0 230000.0 0.5 0.7062 1.0 1980992 ChemDiv1_024217 OC1(C2CCCCC2=NN1C(=O)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M18 compound treatment 730829.0 268000.0 0.55 668714.0 206000.0 0.45 0.7055 0.9943 1639775 ChemDiv1_024218 CCN(CC)C(=O)C1C2CC(C)(Oc3ccccc23)N(CCO)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M19 compound treatment 721962.0 259000.0 0.53 743246.0 280000.0 0.61 0.8066 0.998 1630486 ChemDiv1_024219 Brc1cccc(c1)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M20 compound treatment 652778.0 190000.0 0.39 677155.0 214000.0 0.46 0.6045 0.9964 1786277 ChemDiv1_024220 CC(=O)OCC1OC(C(OC(=O)C)C(OC(=O)C)C1OC(=O)C)n2cc(F)c(=O)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M21 compound treatment 725675.0 262000.0 0.54 730294.0 267000.0 0.58 0.7922 0.9995 1490205 ChemDiv1_024221 COc1cc(ccc1OCc2ccccc2)C3CC(=O)Nc4ccc5ccccc5c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M22 compound treatment 681651.0 218000.0 0.45 666944.0 204000.0 0.44 0.631 0.9999 1980993 ChemDiv1_024222 COc1ccc(cc1)C2(CCNCc3ccc(Cl)cc3)CCOC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M23 mock treatment 695880.0 233000.0 0.48 681314.0 218000.0 0.47 0.6738 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 M24 mock treatment 358162.0 -105000.0 -0.22 274797.0 -188000.0 -0.41 -0.4413 -0.9566 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N01 compound treatment 637543.0 174000.0 0.36 610451.0 148000.0 0.32 0.4802 0.9982 1277230 ChemDiv1_024223 COc1ccc(OC)c(N=c2ssc3c2-c4ccc(C)cc4NC3(C)C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N02 compound treatment 649667.0 186000.0 0.38 622015.0 159000.0 0.34 0.5156 0.9985 1980994 ChemDiv1_024224 CCNC(=O)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N03 compound treatment 653030.0 190000.0 0.39 615038.0 152000.0 0.33 0.5098 0.9963 1123159 ChemDiv1_024225 CCOc1ccc-2c(c1)C(=O)c3cc(O)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N04 compound treatment 657986.0 195000.0 0.4 633343.0 170000.0 0.37 0.5451 0.9991 1937442 ChemDiv1_024226 OCCCNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N05 compound treatment 719491.0 256000.0 0.53 674627.0 212000.0 0.46 0.698 0.9974 1332453 ChemDiv1_024227 CC(=O)OCC1OC(Sc2cccc3cccnc23)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N06 compound treatment 683239.0 220000.0 0.45 641088.0 178000.0 0.39 0.5938 0.9967 1980995 ChemDiv1_024228 COc1ccc(OC)c(NC(=O)C(=O)NCC2CCCO2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N07 compound treatment 698206.0 235000.0 0.48 695991.0 233000.0 0.5 0.6997 0.9998 1980996 ChemDiv1_024229 Nc1ccc(Br)cc1c2n[nH]c(=S)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N08 compound treatment 665885.0 203000.0 0.42 671404.0 208000.0 0.45 0.6148 0.9993 1716494 ChemDiv1_024230 CCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(OCC=C)c(OC)c3)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N09 compound treatment 753376.0 290000.0 0.6 708655.0 246000.0 0.53 0.7996 0.9983 1524116 ChemDiv1_024231 Clc1ccccc1N2C(=O)c3sc4nnc(c5ccccc5)c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N10 compound treatment 717145.0 254000.0 0.52 651817.0 189000.0 0.41 0.6597 0.9925 1369097 ChemDiv1_024232 COc1ccc(cc1)C(=O)N2C(CC(=Nc3ccccc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N11 compound treatment 713254.0 250000.0 0.52 730388.0 267000.0 0.58 0.7743 0.9984 1707229 ChemDiv1_024233 Fc1ccc(cc1)C(=O)Nc2ncnc3oc(c(c4ccccc4)c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N12 compound treatment 700940.0 238000.0 0.49 678478.0 216000.0 0.47 0.6768 0.9997 1424570 ChemDiv1_024234 Cc1cccc(c1)C2N3CC4(C)CN2CC(C)(C3)C4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N13 compound treatment 708738.0 245000.0 0.51 712911.0 250000.0 0.54 0.7409 0.9995 1980997 ChemDiv1_024235 CCCN(CCC)CC(O)CN(c1ccccc1OC)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N14 compound treatment 717309.0 254000.0 0.52 726134.0 263000.0 0.57 0.7737 0.9991 1599702 ChemDiv1_024236 CC(C)C1(CN2CC3(CN(C1)C2c4ccccc4C)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N15 compound treatment 727425.0 264000.0 0.55 689314.0 226000.0 0.49 0.7321 0.9986 1265999 ChemDiv1_024237 OC(CN(C1CCCCC1)C2CCCCC2)CN(c3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N16 compound treatment 721158.0 258000.0 0.53 665683.0 203000.0 0.44 0.6868 0.9954 1980998 ChemDiv1_024238 COc1ccc(cc1c2[nH]c(nc2c3ccccc3)c4cc(OC)c(OC)c(OC)c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N17 compound treatment 722011.0 259000.0 0.53 707725.0 245000.0 0.53 0.7524 1.0 1980999 ChemDiv1_024239 Cc1cccc(c1)C2=Nc3ccccc3N=C(C2)c4cc(C)ccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N18 compound treatment 704043.0 241000.0 0.5 675747.0 213000.0 0.46 0.6772 0.9993 1280503 ChemDiv1_024240 CC(CCCc1ccc(F)cc1)c2cc(O)c3C4=C(CCN(CC#C)C4)C(C)(C)Oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N19 compound treatment 709656.0 246000.0 0.51 726166.0 263000.0 0.57 0.7625 0.9984 1981000 ChemDiv1_024241 Cc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4ccc(C)cc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N20 compound treatment 693819.0 231000.0 0.48 704779.0 242000.0 0.52 0.7067 0.9989 1461704 ChemDiv1_024242 CCC(C)c1ccc(O)c(CN2CCCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N21 compound treatment 737194.0 274000.0 0.57 735733.0 273000.0 0.59 0.8174 0.9998 1981001 ChemDiv1_024243 COc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4cc(Cl)ccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N22 compound treatment 680925.0 218000.0 0.45 694418.0 232000.0 0.5 0.672 0.9985 1981002 ChemDiv1_024244 CC(C)Oc1ccccc1NC(=O)C2OC3OC4(CCCCC4)OC3C5OC6(CCCCC6)OC52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N23 mock treatment 724966.0 262000.0 0.54 707600.0 245000.0 0.53 0.7565 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 N24 mock treatment 390205.0 -73100.0 -0.15 371985.0 -90900.0 -0.2 -0.2458 -0.9914 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O01 compound treatment 650363.0 187000.0 0.39 572061.0 109000.0 0.24 0.4401 0.9722 1981003 ChemDiv1_024245 Cc1cccc(NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O02 compound treatment 631188.0 168000.0 0.35 604978.0 142000.0 0.31 0.4625 0.9982 1981004 ChemDiv1_024246 CC(C)NC(=O)C1(CCCC1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O03 compound treatment 663482.0 200000.0 0.41 654079.0 191000.0 0.41 0.5848 1.0 1733789 ChemDiv1_024247 CN(C(=O)C)c1ccc(NC(=O)COc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O04 compound treatment 628193.0 165000.0 0.34 623071.0 160000.0 0.35 0.4859 1.0 1981005 ChemDiv1_024248 FC(F)(F)c1ccc(cc1)C2C3C(ON2c4ccc(Cl)cc4)C(=O)N(Cc5ccccc5)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O05 compound treatment 668751.0 205000.0 0.42 653593.0 191000.0 0.41 0.5918 0.9999 1981006 ChemDiv1_024249 Cc1ccc(cc1)S(=O)(=O)N2C3NC(N(c4ccccc34)S(=O)(=O)c5ccc(C)cc5)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O06 compound treatment 639647.0 176000.0 0.36 624465.0 162000.0 0.35 0.5047 0.9998 1981007 ChemDiv1_024250 CC(C)N(C(=O)CO[C@H]1[C@H](O[C@@H]2OC3(CCCCC3)O[C@H]12)C4COC5(CCCCC5)O4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O07 compound treatment 664858.0 202000.0 0.42 660214.0 197000.0 0.43 0.5962 0.9999 1981008 ChemDiv1_024251 CC(C)C(=O)C1=Cc2cc(ccc2OC1N3CCOCC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O08 compound treatment 657045.0 194000.0 0.4 659119.0 196000.0 0.42 0.5831 0.9996 1541817 ChemDiv1_024252 O=C1N(Cc2ccccc2)C(=O)c3c1sc4nnc(c5cccs5)c(=O)n34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O09 compound treatment 703013.0 240000.0 0.49 672967.0 210000.0 0.45 0.6714 0.9991 1949752 ChemDiv1_024253 COC(=O)C1=NNC2(C)C1C(=O)N(C2=O)c3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O10 compound treatment 651848.0 189000.0 0.39 662921.0 200000.0 0.43 0.5814 0.9986 1651584 ChemDiv1_024254 CN1CCN(CC1)C(=O)c2cc3C(=O)CC(C)(C)Cc3n(c4ccc(Cl)cc4)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O11 compound treatment 690123.0 227000.0 0.47 652015.0 189000.0 0.41 0.6205 0.9977 1471722 ChemDiv1_024255 Fc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O12 compound treatment 661381.0 198000.0 0.41 634049.0 171000.0 0.37 0.5511 0.9988 1552022 ChemDiv1_024256 Clc1ccc(cc1)S(=O)(=O)NC2C(N3CCN(CC3)C(=O)c4ccccc4)c5cccc6cccc2c56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O13 compound treatment 703320.0 240000.0 0.5 664853.0 202000.0 0.44 0.6595 0.998 1625788 ChemDiv1_024257 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(C)c(C)c5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O14 compound treatment 667285.0 204000.0 0.42 621570.0 159000.0 0.34 0.5406 0.9949 1178670 ChemDiv1_024258 CN(C)C1C(NS(=O)(=O)c2ccc(Cl)cc2)c3cccc4cccc1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O15 compound treatment 713275.0 250000.0 0.52 665270.0 202000.0 0.44 0.6746 0.9967 1173637 ChemDiv1_024259 Oc1ccc2ccccc2c1CN3CCC(Cc4ccccc4)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O16 compound treatment 667908.0 205000.0 0.42 628864.0 166000.0 0.36 0.5527 0.9967 1941275 ChemDiv1_024260 CCOC(=O)C1=C(Nc2ccccc2)S/C(=C\c3ccccc3Cl)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O17 compound treatment 715522.0 252000.0 0.52 707274.0 244000.0 0.53 0.7422 1.0 1981009 ChemDiv1_024261 CCN1C=CC(=Cc2sc3ccccc3[n+]2CCCS(=O)(=O)O)C=C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O18 compound treatment 703936.0 241000.0 0.5 649676.0 187000.0 0.4 0.6371 0.9948 1651087 ChemDiv1_024262 CCCC(CCC)C(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN4CCN(C)CC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O19 compound treatment 725849.0 263000.0 0.54 685130.0 222000.0 0.48 0.7234 0.9982 1574616 ChemDiv1_024263 CN(C)c1ccc(cc1)C2N(CCN2C(=O)c3ccc(C)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O20 compound treatment 689447.0 226000.0 0.47 649510.0 187000.0 0.4 0.6157 0.9974 1544492 ChemDiv1_024264 Fc1cn(C2OC(COC(=O)c3ccccc3)C(OC(=O)c4ccccc4)C2OC(=O)c5ccccc5)c(=O)[nH]c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O21 compound treatment 730674.0 267000.0 0.55 695134.0 232000.0 0.5 0.7457 0.9989 1981010 ChemDiv1_024265 COc1ccc(cc1)C2CC(=O)C3=C(C2)c4c(NC3c5ccc(OC)c(OC)c5)ccc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O22 compound treatment 649664.0 186000.0 0.38 644096.0 181000.0 0.39 0.5494 1.0 1607393 ChemDiv1_024266 CCC(=O)N(CCC1(CCOC(C)(C)C1)c2ccc(OC)cc2)Cc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O23 mock treatment 684435.0 221000.0 0.46 657246.0 194000.0 0.42 0.6203 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 O24 mock treatment 213538.0 -250000.0 -0.52 306317.0 -157000.0 -0.34 -0.6042 -0.9793 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P01 compound treatment 645000.0 182000.0 0.38 587060.0 124000.0 0.27 0.4553 0.9866 1981011 ChemDiv1_024267 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)Nc3c(OC)cccc23)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P02 compound treatment 655065.0 192000.0 0.4 604085.0 141000.0 0.31 0.496 0.9918 1937364 ChemDiv1_024268 COc1ccc(CCNC(=O)C(=O)Nc2ccc3OCCOc3c2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P03 compound treatment 660327.0 197000.0 0.41 609441.0 147000.0 0.32 0.5119 0.9924 1191185 ChemDiv1_024269 CCOc1ccc-2c(c1)C(=O)c3cc(OCC(=O)OC)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P04 compound treatment 642077.0 179000.0 0.37 592728.0 130000.0 0.28 0.4597 0.9909 1981012 ChemDiv1_024270 CC(C)CNC(=O)C(=O)Nc1cccc(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P05 compound treatment 664730.0 201000.0 0.42 630018.0 167000.0 0.36 0.5498 0.9976 1981013 ChemDiv1_024271 Cc1nc2sccn2c(=O)c1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P06 compound treatment 637901.0 175000.0 0.36 610115.0 147000.0 0.32 0.4802 0.9981 1256764 ChemDiv1_024272 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P07 compound treatment 665064.0 202000.0 0.42 615434.0 153000.0 0.33 0.528 0.9934 1981014 ChemDiv1_024273 CC1(C)CC(=C(C(C2=C(O)CC(C)(C)CC2=O)c3ccc(o3)[N+](=O)[O-])C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P08 compound treatment 639571.0 176000.0 0.36 608784.0 146000.0 0.32 0.4806 0.9975 1305388 ChemDiv1_024274 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(C)C)C(=O)c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P09 compound treatment 649160.0 186000.0 0.38 639563.0 177000.0 0.38 0.5417 1.0 1568271 ChemDiv1_024275 Clc1ccc(cc1Cl)N2C(=O)c3sc4nnc(c5ccccc5)c(=O)n4c3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P10 compound treatment 672516.0 209000.0 0.43 633788.0 171000.0 0.37 0.567 0.997 1981015 ChemDiv1_024276 Cc1ccc(cc1)C(=O)N2C(CC(=Nc3ccccc23)c4ccc(Br)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P11 compound treatment 692927.0 230000.0 0.47 639889.0 177000.0 0.38 0.6061 0.9944 1226573 ChemDiv1_024277 O=C(Nc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4)c5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P12 compound treatment 628095.0 165000.0 0.34 644276.0 181000.0 0.39 0.5182 0.9975 1189908 ChemDiv1_024278 CC(C)C1(CN2CC3(CN(C1)C2c4ccccc4Cl)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P13 compound treatment 626302.0 163000.0 0.34 620379.0 157000.0 0.34 0.479 1.0 1981016 ChemDiv1_024279 CCCN(CCC)CC(O)CN(c1ccc(OC)cc1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P14 compound treatment 663377.0 200000.0 0.41 630488.0 168000.0 0.36 0.5486 0.9979 1423122 ChemDiv1_024280 CC(C)C1(CN2CC3(CN(C1)C2c4ccc(OCC=C)cc4)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P15 compound treatment 666456.0 203000.0 0.42 636232.0 173000.0 0.38 0.5618 0.9985 1337209 ChemDiv1_024281 O=C(N1CC(=O)Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P16 compound treatment 720308.0 257000.0 0.53 643800.0 181000.0 0.39 0.652 0.9888 1981017 ChemDiv1_024282 COc1ccc(cc1c2[nH]c(nc2c3ccccc3)c4cc(OC)c(O)c(OC)c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P17 compound treatment 688115.0 225000.0 0.46 651976.0 189000.0 0.41 0.6176 0.998 1981018 ChemDiv1_024283 Cc1ccc(cc1)C2=Nc3ccccc3N=C(C2)c4cc(C)ccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P18 compound treatment 708941.0 246000.0 0.51 646534.0 184000.0 0.4 0.6396 0.9927 1447757 ChemDiv1_024284 CCOC(=O)CCCN1CCC2=C(C1)c3c(O)cc(cc3OC2(C)C)C(C)CCCc4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P19 compound treatment 708947.0 246000.0 0.51 655194.0 192000.0 0.42 0.6529 0.9952 1981019 ChemDiv1_024285 Cc1ccc(C2=Nc3ccccc3N=C(C2)c4cccc(F)c4)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P20 compound treatment 759005.0 296000.0 0.61 626049.0 163000.0 0.35 0.6814 0.9661 1699483 ChemDiv1_024286 CC(C)(C)c1cc(CN2CCCCC2)c(O)c(c1)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P21 compound treatment 667811.0 205000.0 0.42 651998.0 189000.0 0.41 0.588 0.9999 1981020 ChemDiv1_024287 COc1ccc(O)c(c1)C2=Nc3ccccc3N=C(C2)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P22 compound treatment 681502.0 218000.0 0.45 644320.0 181000.0 0.39 0.5962 0.9977 1981021 ChemDiv1_024288 CCCCCOc1ccc(NC(=O)C2OC3OC4(CCCCC4)OC3C5OC6(CCCCC6)OC52)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P23 mock treatment 621899.0 159000.0 0.33 607737.0 145000.0 0.31 0.4532 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.655 P24 mock treatment 341177.0 -122000.0 -0.25 356864.0 -106000.0 -0.23 -0.3405 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A01 compound treatment 622063.0 152000.0 0.31 587861.0 108000.0 0.23 0.3868 0.9892 1981022 ChemDiv1_024289 CCOC(=O)c1ccc(N=c2ssc3c2-c4ccccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A02 compound treatment 612994.0 143000.0 0.3 567254.0 87000.0 0.19 0.3421 0.9763 1630124 ChemDiv1_024290 CC(C)OC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN4CCN(CCO)CC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A03 compound treatment 634821.0 165000.0 0.34 594968.0 115000.0 0.25 0.4163 0.988 1577882 ChemDiv1_024291 C=CCOc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A04 compound treatment 657131.0 187000.0 0.39 598499.0 118000.0 0.26 0.4543 0.98 1536653 ChemDiv1_024292 O=C(NCC1(CCOCC1)c2ccccc2)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A05 compound treatment 681959.0 212000.0 0.44 611837.0 132000.0 0.28 0.5109 0.9783 1589433 ChemDiv1_024293 CC1(C)CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A06 compound treatment 678917.0 209000.0 0.43 630215.0 150000.0 0.32 0.5346 0.9901 1223905 ChemDiv1_024294 COc1ccc(cc1OC)C2(CCOCC2)C(=O)N3CCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A07 compound treatment 761833.0 292000.0 0.6 695299.0 215000.0 0.47 0.7553 0.9918 1981023 ChemDiv1_024295 Clc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A08 compound treatment 685880.0 216000.0 0.45 633234.0 153000.0 0.33 0.5494 0.9893 1370415 ChemDiv1_024296 CC1C=C(C)C2C(C)C1(COC(=O)C)COC2c3ccc(OC(=O)C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A09 compound treatment 668126.0 198000.0 0.41 642924.0 163000.0 0.35 0.5383 0.9972 1456732 ChemDiv1_024297 CC(=O)N1C(CC(=Nc2ccccc12)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A10 compound treatment 687424.0 218000.0 0.45 634083.0 154000.0 0.33 0.553 0.9892 1536696 ChemDiv1_024298 CN1C(=O)N(C)C(O)(c2ccccc2)C1(O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A11 compound treatment 674773.0 205000.0 0.42 618764.0 139000.0 0.3 0.5111 0.9858 1587958 ChemDiv1_024299 CC1=C(C(C(=C(N1)SCc2ccccc2)C#N)c3ccncc3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A12 compound treatment 682669.0 213000.0 0.44 638065.0 158000.0 0.34 0.5521 0.9923 1187851 ChemDiv1_024300 Cc1c(OCC(=O)OCC=C)ccc2c3CCCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A13 compound treatment 674363.0 204000.0 0.42 657296.0 177000.0 0.38 0.5694 0.9988 1419781 ChemDiv1_024301 N#CC(=C1CCCCC1)c2nc(cs2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A14 compound treatment 687586.0 218000.0 0.45 651136.0 171000.0 0.37 0.5793 0.9953 1981024 ChemDiv1_024302 CCCCCCc1cc2c(cc(=O)oc2cc1OCC(=O)N)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A15 compound treatment 689462.0 220000.0 0.45 632524.0 152000.0 0.33 0.5536 0.9877 1981025 ChemDiv1_024303 Fc1ccc(CN2c3cccc4cccc(c34)S2(=O)=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A16 compound treatment 694483.0 225000.0 0.46 621406.0 141000.0 0.31 0.5439 0.9795 1296695 ChemDiv1_024304 OC1(CCCCC12)OC3(CCCCC3)C4CCCCC24O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A17 compound treatment 706466.0 237000.0 0.49 639058.0 159000.0 0.34 0.5884 0.9852 1378505 ChemDiv1_024305 COc1ccc(CN2CCN(CC(O)Cn3c4ccccc4c5ccccc35)CC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A18 compound treatment 684256.0 214000.0 0.44 640573.0 160000.0 0.35 0.5583 0.9928 1981026 ChemDiv1_024306 CSc1nnc2-c3cccc4cccc(-c2n1)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A19 compound treatment 658673.0 189000.0 0.39 628721.0 148000.0 0.32 0.5028 0.9954 1981027 ChemDiv1_024307 COc1ccc(OC)c(c1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A20 compound treatment 641544.0 172000.0 0.35 633210.0 153000.0 0.33 0.4847 0.9994 1783776 ChemDiv1_024308 O=c1[nH]c(CN2CCCC3(CCCCC3)C2)nc4-c5ccccc5CC6(CCCCC6)c41 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A21 compound treatment 665404.0 196000.0 0.4 608097.0 128000.0 0.28 0.4811 0.983 1981028 ChemDiv1_024309 Brc1cccc(c1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A22 compound treatment 619765.0 150000.0 0.31 587882.0 108000.0 0.23 0.3835 0.9902 1672361 ChemDiv1_024310 CCC1(C)Cc2ccccc2-c3nc4SCCn4c(=O)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A23 mock treatment 611856.0 142000.0 0.29 578609.0 98400.0 0.21 0.3578 0.9877 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 A24 mock treatment 275865.0 -194000.0 -0.4 222324.0 -258000.0 -0.56 -0.678 -0.9867 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B01 compound treatment 606160.0 136000.0 0.28 581881.0 102000.0 0.22 0.3545 0.9926 1641622 ChemDiv1_024311 COc1ccccc1n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6cnnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B02 compound treatment 610617.0 141000.0 0.29 619078.0 139000.0 0.3 0.4179 0.9999 1119128 ChemDiv1_024312 Cc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(F)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B03 compound treatment 648449.0 179000.0 0.37 658664.0 178000.0 0.39 0.5337 0.9997 1707596 ChemDiv1_024313 CCc1ccc(cc1)C2CC(=O)Nc3cc(C)c(C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B04 compound treatment 669312.0 199000.0 0.41 654483.0 174000.0 0.38 0.5578 0.999 1599616 ChemDiv1_024314 COc1ccc(C2N(CCCN(C)C)C(=O)C(=C2C(=O)c3ccc(Cl)cc3)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B05 compound treatment 675198.0 205000.0 0.42 692127.0 212000.0 0.46 0.624 0.9992 1568302 ChemDiv1_024315 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCC5)n6cnnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B06 compound treatment 636114.0 166000.0 0.34 669735.0 189000.0 0.41 0.5326 0.9961 1374637 ChemDiv1_024316 COc1ccc(cc1OC)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccccc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B07 compound treatment 757373.0 287000.0 0.59 770249.0 290000.0 0.63 0.8635 0.9996 1981029 ChemDiv1_024317 Oc1ccc(/C=C\2/SC(=NC2=O)N3CCN(CC3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B08 compound treatment 700543.0 231000.0 0.48 709645.0 229000.0 0.5 0.6878 0.9998 1295932 ChemDiv1_024318 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccccc3F)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B09 compound treatment 736159.0 266000.0 0.55 711377.0 231000.0 0.5 0.7424 0.9989 1418830 ChemDiv1_024319 COc1ccc(cc1)C(=O)c2oc3ccc4c(C)cc(=O)oc4c3c2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B10 compound treatment 692063.0 222000.0 0.46 692713.0 212000.0 0.46 0.6495 1.0 1306820 ChemDiv1_024320 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccc(OCC=C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B11 compound treatment 703997.0 234000.0 0.48 700634.0 220000.0 0.48 0.679 1.0 1981030 ChemDiv1_024321 CC1(C)Cc2ccccc2C3=C(C(=O)N4CCCCC4)C(=O)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B12 compound treatment 687703.0 218000.0 0.45 692138.0 212000.0 0.46 0.6422 1.0 1233001 ChemDiv1_024322 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(F)cc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B13 compound treatment 716489.0 247000.0 0.51 706466.0 226000.0 0.49 0.7062 0.9998 1356668 ChemDiv1_024323 COc1cc2CC(C)(C)N=C(C(C)C)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B14 compound treatment 677103.0 207000.0 0.43 704943.0 225000.0 0.49 0.6464 0.998 1491107 ChemDiv1_024324 CCCOc1ccc(C=c2sc3nc(=O)c(C)nn3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B15 compound treatment 728975.0 259000.0 0.53 727935.0 248000.0 0.54 0.7573 1.0 1551289 ChemDiv1_024325 Clc1ccc(Cn2cnc3c(C#N)c4CCCCn4c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B16 compound treatment 670074.0 200000.0 0.41 654438.0 174000.0 0.38 0.5588 0.9989 1981031 ChemDiv1_024326 COc1ccc(cc1)C2(CCCCC2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B17 compound treatment 715724.0 246000.0 0.51 740827.0 261000.0 0.56 0.7576 0.9986 1174577 ChemDiv1_024327 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccc(Cl)cc3)c4ccco4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B18 compound treatment 671823.0 202000.0 0.42 674071.0 194000.0 0.42 0.5914 1.0 1488392 ChemDiv1_024328 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B19 compound treatment 687356.0 217000.0 0.45 691532.0 211000.0 0.46 0.6408 1.0 1420676 ChemDiv1_024329 CCCOC(=O)c1cccc(c1)N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B20 compound treatment 683176.0 213000.0 0.44 670805.0 191000.0 0.41 0.603 0.9995 1595216 ChemDiv1_024330 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B21 compound treatment 686641.0 217000.0 0.45 672212.0 192000.0 0.42 0.6102 0.9993 1981032 ChemDiv1_024331 CCCCCCSc1nnc2n(c3ccccc3)c(=O)c4c(C)c(C)sc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B22 compound treatment 672198.0 202000.0 0.42 661808.0 182000.0 0.39 0.5732 0.9995 1981033 ChemDiv1_024332 COc1ccccc1C2NC(=S)NC(=C2C(=O)Nc3ccc(C)cc3C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B23 mock treatment 657699.0 188000.0 0.39 794086.0 314000.0 0.68 0.7545 0.9646 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 B24 mock treatment 205035.0 -265000.0 -0.55 231717.0 -249000.0 -0.54 -0.767 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C01 compound treatment 621123.0 151000.0 0.31 617288.0 137000.0 0.3 0.4305 0.9997 1981034 ChemDiv1_024333 CCOC(=O)c1ccc(N=c2ssc3c2-c4cc(OC)ccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C02 compound treatment 655853.0 186000.0 0.38 642500.0 162000.0 0.35 0.5198 0.999 1981035 ChemDiv1_024334 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN(CC)CC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C03 compound treatment 686075.0 216000.0 0.45 675567.0 195000.0 0.42 0.6145 0.9996 1186866 ChemDiv1_024335 O=c1oc2cc(OCC#C)ccc2c3CCCCc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C04 compound treatment 673042.0 203000.0 0.42 660802.0 181000.0 0.39 0.5729 0.9994 1444945 ChemDiv1_024336 COc1ccc(CC(=O)NCC2(CCOCC2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C05 compound treatment 698707.0 229000.0 0.47 682142.0 202000.0 0.44 0.643 0.9992 1355857 ChemDiv1_024337 CC1CC2(CC(C)(OC2=O)c3csc(NCC=C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C06 compound treatment 681733.0 212000.0 0.44 665890.0 186000.0 0.4 0.5933 0.9991 1575159 ChemDiv1_024338 Cc1ccc2N(Cc3ccccc3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C07 compound treatment 836607.0 367000.0 0.76 852142.0 372000.0 0.8 1.1045 0.9995 1981036 ChemDiv1_024339 Fc1ccc(cc1)C2=CC(c3ccccc3)n4c(N2)nc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C08 compound treatment 705134.0 235000.0 0.49 700182.0 220000.0 0.48 0.68 1.0 1605287 ChemDiv1_024340 CC1C=C(C)C2C(C)C1(COC(=O)C)COC2c3ccccc3OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C09 compound treatment 728023.0 258000.0 0.53 723917.0 244000.0 0.53 0.7497 1.0 1604240 ChemDiv1_024341 O=C(N1C(CC(=Nc2ccccc12)c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C10 compound treatment 717506.0 248000.0 0.51 729145.0 249000.0 0.54 0.7424 0.9997 1700240 ChemDiv1_024342 CN1C(=O)NC2(N(C)C(=O)N(C)C12c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C11 compound treatment 726024.0 256000.0 0.53 740582.0 260000.0 0.56 0.7723 0.9995 1981037 ChemDiv1_024343 Brc1ccc(cc1)c2csc(n2)/C(=C/C3CCCCC3)/C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C12 compound treatment 682335.0 212000.0 0.44 713607.0 233000.0 0.51 0.6673 0.9975 1598598 ChemDiv1_024344 Cc1cc(OCC(=O)OCC=C)c2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C13 compound treatment 681213.0 211000.0 0.44 710188.0 230000.0 0.5 0.6604 0.9978 1594469 ChemDiv1_024345 Cc1ccc(cc1)c2csc(n2)C(=C3CCC(CC3)c4ccccc4)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C14 compound treatment 725342.0 255000.0 0.53 722237.0 242000.0 0.52 0.7432 1.0 1981038 ChemDiv1_024346 CCCCCCc1cc2c3CCCCc3c(=O)oc2cc1OCC(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C15 compound treatment 759387.0 290000.0 0.6 750675.0 270000.0 0.59 0.8365 0.9999 1565368 ChemDiv1_024347 Cc1cc2NC(=O)CC(c3ccc(F)c(Br)c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C16 compound treatment 704516.0 235000.0 0.48 717240.0 237000.0 0.51 0.7052 0.9996 1981039 ChemDiv1_024348 OC(=O)c1cccc(NC2=C(N3CCOCC3)C(=O)c4ccccc4C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C17 compound treatment 754903.0 285000.0 0.59 740754.0 261000.0 0.56 0.8147 0.9998 1517374 ChemDiv1_024349 OC(CN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3)Cn4c5ccccc5c6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C18 compound treatment 698641.0 229000.0 0.47 773490.0 293000.0 0.63 0.7827 0.9894 1981040 ChemDiv1_024350 C(Sc1nnc2-c3cccc4cccc(-c2n1)c34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C19 compound treatment 696805.0 227000.0 0.47 721972.0 242000.0 0.52 0.7012 0.9985 1981041 ChemDiv1_024351 O=C(CN1C2=NCCN2c3ccccc13)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C20 compound treatment 685257.0 215000.0 0.44 697792.0 218000.0 0.47 0.6473 0.9996 1783777 ChemDiv1_024352 CC1(C)CC2(CCCN(Cc3nc4-c5ccccc5CC6(CCCCC6)c4c(=O)[nH]3)C2)CCO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C21 compound treatment 700996.0 231000.0 0.48 709807.0 230000.0 0.5 0.6887 0.9998 1981042 ChemDiv1_024353 Fc1ccc(cc1)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C22 compound treatment 701954.0 232000.0 0.48 701399.0 221000.0 0.48 0.6772 1.0 1718251 ChemDiv1_024354 CCSc1nnc2n(c3ccccc3OC)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C23 mock treatment 678226.0 208000.0 0.43 695324.0 215000.0 0.47 0.6333 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 C24 mock treatment 210648.0 -259000.0 -0.54 253006.0 -227000.0 -0.49 -0.7262 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D01 compound treatment 660277.0 190000.0 0.39 596196.0 116000.0 0.25 0.4554 0.9765 1294687 ChemDiv1_024355 COc1ccccc1n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(S)nnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D02 compound treatment 654603.0 185000.0 0.38 643066.0 163000.0 0.35 0.5188 0.9992 1658128 ChemDiv1_024356 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccc(F)cc3)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D03 compound treatment 689015.0 219000.0 0.45 682452.0 202000.0 0.44 0.6293 0.9999 1981043 ChemDiv1_024357 CCOCCOC(=O)C1=C(C)NC(=O)CC1c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D04 compound treatment 686495.0 217000.0 0.45 664080.0 184000.0 0.4 0.5975 0.9983 1468825 ChemDiv1_024358 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccc(F)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D05 compound treatment 699208.0 229000.0 0.47 700588.0 220000.0 0.48 0.672 1.0 1981044 ChemDiv1_024359 Cn1c(CC(=O)Nc2ccccc2C(F)(F)F)c(Sc3ccccc3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D06 compound treatment 696956.0 227000.0 0.47 670205.0 190000.0 0.41 0.6222 0.9979 1717862 ChemDiv1_024360 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccccc3F)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D07 compound treatment 721233.0 251000.0 0.52 683936.0 204000.0 0.44 0.6786 0.9967 1981045 ChemDiv1_024361 Cc1ccccc1N2CCN(CC2)C3=NC(=O)/C(=C\c4ccccc4)/S3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D08 compound treatment 707020.0 237000.0 0.49 690228.0 210000.0 0.45 0.6675 0.9993 1584251 ChemDiv1_024362 CCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(cc3)C(C)(C)C)c4nccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D09 compound treatment 735150.0 265000.0 0.55 698151.0 218000.0 0.47 0.7207 0.9972 1981046 ChemDiv1_024363 C/C(=N\O)/c1oc2ccc3c(C)cc(=O)oc3c2c1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D10 compound treatment 741447.0 272000.0 0.56 698945.0 219000.0 0.47 0.7311 0.9965 1627523 ChemDiv1_024364 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(C)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D11 compound treatment 728288.0 258000.0 0.53 726643.0 246000.0 0.53 0.7543 1.0 1981047 ChemDiv1_024365 CCNC(=O)/C=C/1\NC(C)(C)Cc2c1ccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D12 compound treatment 677303.0 207000.0 0.43 686163.0 206000.0 0.45 0.6179 0.9998 1572517 ChemDiv1_024366 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(F)cc3)c4cccc(Oc5ccccc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D13 compound treatment 737442.0 268000.0 0.55 694828.0 215000.0 0.46 0.719 0.9963 1402349 ChemDiv1_024367 CC(N1CCn2c3C1CCCc3c4cc(C)ccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D14 compound treatment 719080.0 249000.0 0.51 695299.0 215000.0 0.47 0.6929 0.9988 1981048 ChemDiv1_024368 CCCCOc1ccc(C=c2sc3nc(=O)c(C)nn3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D15 compound treatment 738678.0 269000.0 0.55 767407.0 287000.0 0.62 0.8318 0.9984 1410027 ChemDiv1_024369 COC(=O)Cn1cnc2c(C#N)c3CCCCn3c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D16 compound treatment 673075.0 203000.0 0.42 695003.0 215000.0 0.46 0.6253 0.9987 1981049 ChemDiv1_024370 CCc1ccc(OCCCC(=O)Nc2ccc3OCCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D17 compound treatment 822244.0 352000.0 0.73 740963.0 261000.0 0.56 0.9133 0.9921 1494411 ChemDiv1_024371 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D18 compound treatment 728221.0 258000.0 0.53 704357.0 224000.0 0.49 0.7201 0.9989 1362328 ChemDiv1_024372 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3cccc(C)c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D19 compound treatment 727217.0 257000.0 0.53 703900.0 224000.0 0.48 0.7179 0.9989 1479450 ChemDiv1_024373 Clc1ccc(cc1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D20 compound treatment 708624.0 239000.0 0.49 701496.0 221000.0 0.48 0.6871 0.9999 1324496 ChemDiv1_024374 CCOC(=O)c1cccc(Nc2c(cnc3c(C)cc(C)cc23)C(=O)OCC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D21 compound treatment 710100.0 240000.0 0.5 714924.0 235000.0 0.51 0.7098 0.9999 1360949 ChemDiv1_024375 CCOC(=O)c1c(NC(=S)Nc2ccccc2OC)sc3COC(C)(C)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D22 compound treatment 682263.0 212000.0 0.44 616933.0 137000.0 0.3 0.5192 0.9817 1981050 ChemDiv1_024376 N=C/1N2C(=CSC2=NC(=O)\C1=C/c3ccc(OCc4ccccc4)cc3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D23 mock treatment 685403.0 216000.0 0.44 665729.0 185000.0 0.4 0.5985 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 D24 mock treatment 208700.0 -261000.0 -0.54 234973.0 -245000.0 -0.53 -0.7566 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E01 compound treatment 644613.0 175000.0 0.36 608511.0 128000.0 0.28 0.4513 0.9916 1981051 ChemDiv1_024377 CCOC(=O)c1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E02 compound treatment 634863.0 165000.0 0.34 643653.0 163000.0 0.35 0.4909 0.9998 1918966 ChemDiv1_024378 CCNCC(=O)N1c2ccccc2CCc3ccc(NC(=O)OC(C)C)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E03 compound treatment 646495.0 177000.0 0.36 691240.0 211000.0 0.46 0.5807 0.9938 1532296 ChemDiv1_024379 CCCCn1cnc2oc(c(c3ccccc3)c2c1=N)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E04 compound treatment 659718.0 190000.0 0.39 692108.0 212000.0 0.46 0.6013 0.9969 1238837 ChemDiv1_024380 O=C(CC(c1ccccc1)c2ccccc2)NCC3(CCOCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E05 compound treatment 717395.0 248000.0 0.51 690478.0 210000.0 0.46 0.683 0.9983 1288276 ChemDiv1_024381 Cc1ccc(Nc2nc(cs2)C3(C)CC4(CC(C)(C)OC4=O)C(=O)O3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E06 compound treatment 661160.0 191000.0 0.39 674001.0 194000.0 0.42 0.5757 0.9995 1404282 ChemDiv1_024382 CC(=O)Nc1ccc(N=c2ssc3c2-c4ccccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E07 compound treatment 732527.0 263000.0 0.54 748672.0 268000.0 0.58 0.7942 0.9994 1741965 ChemDiv1_024383 COC(=O)c1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E08 compound treatment 653738.0 184000.0 0.38 634437.0 154000.0 0.33 0.5043 0.9979 1509736 ChemDiv1_024384 CCC(=O)OCC1(COC(C2C1C)c3ccccc3OC(=O)CC)C(C)C=C2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E09 compound treatment 797544.0 328000.0 0.68 827880.0 348000.0 0.75 1.0103 0.9986 1981052 ChemDiv1_024385 FC(F)Oc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E10 compound treatment 692102.0 222000.0 0.46 697807.0 218000.0 0.47 0.6573 0.9999 1407099 ChemDiv1_024386 CC(=O)N1C2C(N(C(=O)C)C1=O)N(C(=O)C)C(=O)N2C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E11 compound treatment 814596.0 345000.0 0.71 701098.0 221000.0 0.48 0.8412 0.9813 1643495 ChemDiv1_024387 Oc1ccccc1c2csc(n2)C(=C3CCCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E12 compound treatment 662053.0 192000.0 0.4 680392.0 200000.0 0.43 0.5868 0.999 1159590 ChemDiv1_024388 CC(=CCOc1cc(C)cc2oc(=O)c3CCCCc3c12)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E13 compound treatment 820671.0 351000.0 0.72 724134.0 244000.0 0.53 0.8853 0.9879 1325013 ChemDiv1_024389 Oc1ccccc1c2csc(n2)C(=C3CCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E14 compound treatment 714870.0 245000.0 0.51 706926.0 227000.0 0.49 0.7045 0.9999 1981053 ChemDiv1_024390 CCCCCCc1cc2c3CCCCc3c(=O)oc2cc1OCC(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E15 compound treatment 683810.0 214000.0 0.44 736637.0 256000.0 0.55 0.7047 0.9936 1218499 ChemDiv1_024391 Cc1cc2NC(=O)CC(c3cccc(F)c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E16 compound treatment 705867.0 236000.0 0.49 690330.0 210000.0 0.45 0.666 0.9994 1981054 ChemDiv1_024392 C(c1ccccc1)n2cnc3cccc4cccc2c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E17 compound treatment 710685.0 241000.0 0.5 732361.0 252000.0 0.55 0.7373 0.9989 1342056 ChemDiv1_024393 O=CN1CCN(CC1)S(=O)(=O)c2ccc-3c(Cc4cc(ccc43)S(=O)(=O)N5CCN(CC5)C=O)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E18 compound treatment 683548.0 214000.0 0.44 726959.0 247000.0 0.53 0.6895 0.9955 1981055 ChemDiv1_024394 Brc1ccccc1NC(=O)CSc2nnc3-c4cccc5cccc(-c3n2)c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E19 compound treatment 730006.0 260000.0 0.54 738565.0 258000.0 0.56 0.775 0.9998 1981056 ChemDiv1_024395 O=C(CN1C2=NCCCN2c3ccccc13)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E20 compound treatment 687390.0 218000.0 0.45 686061.0 206000.0 0.45 0.6325 1.0 1783779 ChemDiv1_024396 CC1(C)CC2(CCCN(Cc3nc4-c5ccccc5CC6(CCCC6)c4c(=O)[nH]3)C2)CCO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E21 compound treatment 722010.0 252000.0 0.52 702777.0 223000.0 0.48 0.7086 0.9992 1981057 ChemDiv1_024397 Fc1ccc(cc1)C(=O)CN2C3=NCCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E22 compound treatment 713422.0 244000.0 0.5 670713.0 190000.0 0.41 0.647 0.9951 1981058 ChemDiv1_024398 CCCCSc1nnc2n(c3ccccc3OC)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E23 mock treatment 693839.0 224000.0 0.46 749033.0 269000.0 0.58 0.7383 0.9935 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 E24 mock treatment 221098.0 -249000.0 -0.51 263802.0 -216000.0 -0.47 -0.6944 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F01 compound treatment 634976.0 165000.0 0.34 602937.0 123000.0 0.27 0.4287 0.9924 1616804 ChemDiv1_024399 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SC(C)C)nnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F02 compound treatment 651206.0 181000.0 0.37 649449.0 169000.0 0.37 0.5236 0.9999 1981059 ChemDiv1_024400 Cc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F03 compound treatment 683306.0 213000.0 0.44 674302.0 194000.0 0.42 0.6085 0.9997 1981060 ChemDiv1_024401 Cc1cc2NC(=O)CC(c3cccc(c3)C(F)(F)F)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F04 compound treatment 692481.0 223000.0 0.46 664593.0 184000.0 0.4 0.607 0.9975 1353005 ChemDiv1_024402 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccccc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F05 compound treatment 683708.0 214000.0 0.44 709290.0 229000.0 0.5 0.6626 0.9983 1628141 ChemDiv1_024403 Cn1c(CC(=O)Nc2ccc(F)cc2)c(Sc3ccccc3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F06 compound treatment 696046.0 226000.0 0.47 703880.0 224000.0 0.48 0.6724 0.9998 1554740 ChemDiv1_024404 COc1ccc(cc1OC)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(F)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F07 compound treatment 806819.0 337000.0 0.7 779015.0 299000.0 0.65 0.9491 0.9993 1981061 ChemDiv1_024405 Cc1ccccc1N2CCN(CC2)C3=NC(=O)/C(=C\c4ccc(O)cc4)/S3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F08 compound treatment 740554.0 271000.0 0.56 719277.0 239000.0 0.52 0.7609 0.9993 1531410 ChemDiv1_024406 CCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Oc4ccccc4)c3)c5nccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F09 compound treatment 777147.0 307000.0 0.63 726992.0 247000.0 0.53 0.8261 0.9963 1981062 ChemDiv1_024407 Nc1cccc(c1)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F10 compound treatment 711676.0 242000.0 0.5 724025.0 244000.0 0.53 0.726 0.9996 1606398 ChemDiv1_024408 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(C)cc3)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F11 compound treatment 748730.0 279000.0 0.58 691577.0 211000.0 0.46 0.7305 0.9935 1981063 ChemDiv1_024409 CN1/C(=C\C(=O)C)/c2ccccc2CC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F12 compound treatment 717139.0 247000.0 0.51 690716.0 210000.0 0.46 0.683 0.9984 1450173 ChemDiv1_024410 Cc1c(oc2ccccc12)C(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F13 compound treatment 737978.0 268000.0 0.55 701348.0 221000.0 0.48 0.7297 0.9974 1981064 ChemDiv1_024411 CC(=O)c1c(C)nc2c(C#N)c(C)n(c3ccc(Br)cc3)c2c1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F14 compound treatment 737234.0 267000.0 0.55 725446.0 245000.0 0.53 0.7655 0.9998 1981065 ChemDiv1_024412 CCCCCOc1ccc(C=c2sc3nc(=O)c(C)nn3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F15 compound treatment 729592.0 260000.0 0.54 749603.0 269000.0 0.58 0.7913 0.9991 1670681 ChemDiv1_024413 Clc1ccc(cc1)C(=O)Cn2cnc3c(C#N)c4CCCCCn4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F16 compound treatment 688149.0 218000.0 0.45 667969.0 188000.0 0.41 0.6059 0.9987 1981066 ChemDiv1_024414 CC(C)(C)c1ccc(OCCCC(=O)Nc2ccc3OCCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F17 compound treatment 756198.0 286000.0 0.59 676946.0 197000.0 0.43 0.719 0.987 1981067 ChemDiv1_024415 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Cl)c(Cl)c2)C#N)c3ccncc3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F18 compound treatment 677497.0 208000.0 0.43 657811.0 178000.0 0.38 0.5748 0.9985 1189721 ChemDiv1_024416 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F19 compound treatment 699259.0 229000.0 0.47 679860.0 200000.0 0.43 0.6403 0.999 1723320 ChemDiv1_024417 CCOC(=O)c1cnc2ccc(C)cc2c1Nc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F20 compound treatment 719610.0 250000.0 0.52 702757.0 223000.0 0.48 0.7051 0.9994 1508713 ChemDiv1_024418 CCCOC(=O)c1ccc(Nc2c(cnc3c(C)cc(C)cc23)C(=O)OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F21 compound treatment 725081.0 255000.0 0.53 709431.0 229000.0 0.5 0.7233 0.9995 1519422 ChemDiv1_024419 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccccc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F22 compound treatment 700924.0 231000.0 0.48 687229.0 207000.0 0.45 0.654 0.9995 1981068 ChemDiv1_024420 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F23 mock treatment 711298.0 241000.0 0.5 670163.0 190000.0 0.41 0.643 0.9954 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 F24 mock treatment 207653.0 -262000.0 -0.54 210847.0 -269000.0 -0.58 -0.7951 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G01 compound treatment 631568.0 162000.0 0.33 604933.0 125000.0 0.27 0.4268 0.9944 1491297 ChemDiv1_024421 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=S)[nH]c(=O)c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G02 compound treatment 607110.0 137000.0 0.28 655599.0 175000.0 0.38 0.4687 0.9896 1981069 ChemDiv1_024422 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G03 compound treatment 674226.0 204000.0 0.42 670456.0 190000.0 0.41 0.5894 0.9999 1663915 ChemDiv1_024423 N=c1n(Cc2ccccc2)cnc3oc(c(c4ccccc4)c13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G04 compound treatment 715750.0 246000.0 0.51 644203.0 164000.0 0.35 0.6098 0.9847 1161966 ChemDiv1_024424 COc1ccc(cc1OC)C2(CNC(=O)CC(c3ccccc3)c4ccccc4)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G05 compound treatment 695379.0 225000.0 0.47 705036.0 225000.0 0.49 0.6732 0.9998 1981070 ChemDiv1_024425 CC(=O)C1(C)CC2(CC(C)(C)OC2=O)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G06 compound treatment 649720.0 180000.0 0.37 693321.0 213000.0 0.46 0.5886 0.9942 1673399 ChemDiv1_024426 CC(=O)Nc1ccc(N=c2ssc3c2-c4cc(C)c(C)cc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G07 compound treatment 702926.0 233000.0 0.48 721142.0 241000.0 0.52 0.7088 0.9992 1865370 ChemDiv1_024427 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G08 compound treatment 688980.0 219000.0 0.45 712891.0 233000.0 0.5 0.6759 0.9986 1155861 ChemDiv1_024428 CCn1cc(Br)c(n1)C(=O)OCC2(COC3C4C2C)C(C)CC4(C)Oc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G09 compound treatment 721417.0 252000.0 0.52 756696.0 276000.0 0.6 0.7902 0.9975 1981071 ChemDiv1_024429 O=C(CSc1nnc(c2ccccc2)c(n1)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G10 compound treatment 678412.0 209000.0 0.43 722190.0 242000.0 0.52 0.6747 0.9953 1981072 ChemDiv1_024430 O=CN1C(OC(=O)c2ccccc2)C(OC(=O)c3ccccc3)N(C=O)C(OC(=O)c4ccccc4)C1OC(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G11 compound treatment 704691.0 235000.0 0.48 726309.0 246000.0 0.53 0.7193 0.9989 1312718 ChemDiv1_024431 CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G12 compound treatment 643520.0 174000.0 0.36 683563.0 203000.0 0.44 0.5646 0.9948 1535634 ChemDiv1_024432 CCOC(=O)COc1cc2oc(=O)c3CCCCc3c2cc1CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G13 compound treatment 701235.0 231000.0 0.48 685588.0 205000.0 0.44 0.652 0.9994 1400648 ChemDiv1_024433 Cc1ccc(cc1)c2csc(n2)C(=C3CCCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G14 compound treatment 695544.0 226000.0 0.47 727765.0 248000.0 0.54 0.7082 0.9976 1981073 ChemDiv1_024434 CCCCCCc1cc2c3CCCCc3c(=O)oc2cc1OC/C=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G15 compound treatment 689413.0 220000.0 0.45 749020.0 269000.0 0.58 0.7318 0.9924 1687005 ChemDiv1_024435 Cc1cc2NC(=O)CC(c3ccc(F)c(F)c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G16 compound treatment 718992.0 249000.0 0.51 725478.0 245000.0 0.53 0.7389 0.9999 1981074 ChemDiv1_024436 C=CCn1cnc2cccc3cccc1c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G17 compound treatment 708057.0 238000.0 0.49 715140.0 235000.0 0.51 0.7071 0.9999 1520734 ChemDiv1_024437 O=CN1CCN(CC1)S(=O)(=O)c2ccc-3c(c2)C(=O)c4cc(ccc43)S(=O)(=O)N5CCN(CC5)C=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G18 compound treatment 639164.0 169000.0 0.35 713865.0 234000.0 0.51 0.6046 0.9837 1981075 ChemDiv1_024438 CCCC[B-]1(O)[N+](=C(C)Nc2ccccc21)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G19 compound treatment 683485.0 214000.0 0.44 685714.0 205000.0 0.44 0.6262 1.0 1981076 ChemDiv1_024439 Fc1ccc(CN2C3=NCCN3c4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G20 compound treatment 668357.0 198000.0 0.41 703730.0 223000.0 0.48 0.6317 0.9966 1981077 ChemDiv1_024440 Sc1nnc2n(c3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G21 compound treatment 661191.0 191000.0 0.39 659524.0 179000.0 0.39 0.5536 1.0 1981078 ChemDiv1_024441 Cc1ccc(cc1)C(O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G22 compound treatment 724814.0 255000.0 0.53 710272.0 230000.0 0.5 0.7242 0.9996 1598508 ChemDiv1_024442 CCSc1nnc2n(CCc3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G23 mock treatment 686173.0 216000.0 0.45 691914.0 212000.0 0.46 0.6397 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 G24 mock treatment 196542.0 -273000.0 -0.56 235371.0 -245000.0 -0.53 -0.7738 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H01 compound treatment 634346.0 164000.0 0.34 589855.0 110000.0 0.24 0.4078 0.9846 1636423 ChemDiv1_024443 COc1ccc(Cn2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SC(C)C)nnc26)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H02 compound treatment 636320.0 166000.0 0.34 625972.0 146000.0 0.32 0.466 0.9991 1540976 ChemDiv1_024444 COc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H03 compound treatment 663209.0 193000.0 0.4 646434.0 166000.0 0.36 0.5365 0.9987 1400373 ChemDiv1_024445 Cc1ccc(cc1)C2CC(=O)Nc3cc(C)c(C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H04 compound treatment 677688.0 208000.0 0.43 634362.0 154000.0 0.33 0.5392 0.9923 1646788 ChemDiv1_024446 Cc1ccc(cc1)C2N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(F)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H05 compound treatment 688749.0 219000.0 0.45 683132.0 203000.0 0.44 0.63 0.9999 1629340 ChemDiv1_024447 Clc1cc2OCOc2cc1C3NC(=O)c4c5CCCCc5sc4N3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H06 compound treatment 683965.0 214000.0 0.44 660594.0 180000.0 0.39 0.5885 0.9981 1376500 ChemDiv1_024448 CC(C)c1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H07 compound treatment 703300.0 233000.0 0.48 699294.0 219000.0 0.47 0.6759 1.0 1981079 ChemDiv1_024449 Cc1ccccc1N2CCN(CC2)C3=NC(=O)/C(=C\c4ccc(OCC=C)cc4)/S3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H08 compound treatment 691086.0 221000.0 0.46 688798.0 209000.0 0.45 0.6421 1.0 1441902 ChemDiv1_024450 CC(C)c1ccc(cc1)C2N(CCN(C)C)C(=O)C(=C2C(=O)c3ccc(C)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H09 compound treatment 711513.0 242000.0 0.5 717400.0 237000.0 0.51 0.7156 0.9999 1981080 ChemDiv1_024451 CC1(C)Cc2ccccc2/C(=C\C(=O)N3CCN(CC3)C(=O)/C=C\4/NC(C)(C)Cc5ccccc45)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H10 compound treatment 696900.0 227000.0 0.47 685841.0 206000.0 0.44 0.646 0.9997 1409347 ChemDiv1_024452 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(Cl)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H11 compound treatment 741157.0 271000.0 0.56 687165.0 207000.0 0.45 0.7126 0.9939 1401097 ChemDiv1_024453 COc1cc2CC(C)(C)[N+](=C(C)c2cc1OC)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H12 compound treatment 716542.0 247000.0 0.51 702936.0 223000.0 0.48 0.7009 0.9996 1981081 ChemDiv1_024454 COCCCNC(=O)c1oc2ccccc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H13 compound treatment 792852.0 323000.0 0.67 705031.0 225000.0 0.49 0.8154 0.988 1633861 ChemDiv1_024455 Cc1c(C#N)c2nc3CCCc3c(c4ccccc4)c2n1Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H14 compound treatment 673155.0 203000.0 0.42 709588.0 229000.0 0.5 0.6477 0.9965 1411624 ChemDiv1_024456 Cc1nn2c(=O)c(=Cc3ccc(OCC=C)cc3)sc2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H15 compound treatment 729697.0 260000.0 0.54 726949.0 247000.0 0.53 0.7568 1.0 1981082 ChemDiv1_024457 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C#N)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H16 compound treatment 658004.0 188000.0 0.39 667876.0 188000.0 0.41 0.5617 0.9998 1981083 ChemDiv1_024458 Clc1ccc(OCCCC(=O)Nc2ccc3OCCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H17 compound treatment 756578.0 287000.0 0.59 717352.0 237000.0 0.51 0.7814 0.9975 1672003 ChemDiv1_024459 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)cc2C)C#N)c3ccncc3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H18 compound treatment 706518.0 237000.0 0.49 650211.0 170000.0 0.37 0.6055 0.9902 1425205 ChemDiv1_024460 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccccc3CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H19 compound treatment 737250.0 267000.0 0.55 716894.0 237000.0 0.51 0.7524 0.9993 1065743 ChemDiv1_024461 CC1=Nc2ccc(cc2C1(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H20 compound treatment 676984.0 207000.0 0.43 643949.0 164000.0 0.35 0.5528 0.9956 1981084 ChemDiv1_024462 CCCCOC(=O)c1ccc(Nc2c(cnc3c(C)cc(C)cc23)C(=O)OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H21 compound treatment 752871.0 283000.0 0.58 716096.0 236000.0 0.51 0.774 0.9977 1981085 ChemDiv1_024463 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3cccc(Br)c3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H22 compound treatment 678708.0 209000.0 0.43 690889.0 211000.0 0.46 0.6272 0.9996 1981086 ChemDiv1_024464 CCOc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H23 mock treatment 691895.0 222000.0 0.46 680349.0 200000.0 0.43 0.6303 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 H24 mock treatment 225120.0 -245000.0 -0.51 223999.0 -256000.0 -0.55 -0.7495 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I01 compound treatment 617225.0 147000.0 0.3 597528.0 117000.0 0.25 0.3946 0.996 1679933 ChemDiv1_024465 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=S)[nH]c(=O)c3C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I02 compound treatment 644263.0 174000.0 0.36 654496.0 174000.0 0.38 0.5212 0.9997 1981087 ChemDiv1_024466 OC(=O)CCC(=O)OCCN1CCN(CCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I03 compound treatment 670614.0 201000.0 0.41 685871.0 206000.0 0.45 0.6077 0.9994 1623184 ChemDiv1_024467 C(c1nc2c3c(c(oc3ncn2n1)c4ccccc4)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I04 compound treatment 646564.0 177000.0 0.36 652263.0 172000.0 0.37 0.5212 0.9999 1784796 ChemDiv1_024468 COc1cc2C(=NCC3(CCCC3)c2cc1OC)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I05 compound treatment 666658.0 197000.0 0.41 666589.0 186000.0 0.4 0.5724 1.0 1240591 ChemDiv1_024469 CC(C)COCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I06 compound treatment 719448.0 250000.0 0.52 645090.0 165000.0 0.36 0.6166 0.9839 1499107 ChemDiv1_024470 CCOc1ccc2N(C(=O)CSc3nc(C)cc(=O)[nH]3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I07 compound treatment 672245.0 202000.0 0.42 695414.0 215000.0 0.47 0.6247 0.9985 1865372 ChemDiv1_024471 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(Cl)cc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I08 compound treatment 696332.0 226000.0 0.47 693939.0 214000.0 0.46 0.6576 1.0 1981088 ChemDiv1_024472 O=C(CN1CCCCC1)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I09 compound treatment 724053.0 254000.0 0.52 703382.0 223000.0 0.48 0.7125 0.9991 1650703 ChemDiv1_024473 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccco2)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I10 compound treatment 678636.0 209000.0 0.43 691721.0 211000.0 0.46 0.6284 0.9995 1981089 ChemDiv1_024474 O=C(N1CCN(C2C1N(CCN2C(=O)c3ccccc3)C(=O)c4ccccc4)C(=O)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I11 compound treatment 655034.0 185000.0 0.38 695073.0 215000.0 0.46 0.599 0.9953 1981090 ChemDiv1_024475 NC1=C(C#N)C2(CCCCC2)C(=C3SC4CCCCC4(O)N31)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I12 compound treatment 614994.0 145000.0 0.3 631742.0 151000.0 0.33 0.4437 0.999 1315379 ChemDiv1_024476 CCc1cc2c3CCCCc3c(=O)oc2cc1OC(C)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I13 compound treatment 718457.0 249000.0 0.51 684139.0 204000.0 0.44 0.6749 0.9972 1981091 ChemDiv1_024477 CC1CCC/C(=C(\C#N)/c2nc(cs2)c3ccc(C)cc3)/C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I14 compound treatment 666492.0 197000.0 0.41 715607.0 235000.0 0.51 0.6472 0.9937 1520427 ChemDiv1_024478 CC[N+]1(CCCC2CN3C(CCCC3=O)C4CCC1)C24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I15 compound treatment 660996.0 191000.0 0.39 717549.0 237000.0 0.51 0.6421 0.9915 1981092 ChemDiv1_024479 Cc1cc2NC(=O)CC(c3ccc(OC(F)(F)F)cc3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I16 compound treatment 669484.0 200000.0 0.41 679334.0 199000.0 0.43 0.596 0.9997 1981093 ChemDiv1_024480 CN(C)c1ccc(cc1)c2nc3cccc4cccc([nH]2)c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I17 compound treatment 710884.0 241000.0 0.5 677003.0 197000.0 0.43 0.6529 0.997 1299008 ChemDiv1_024481 CCOc1ccc(CN2CCN(CC(O)Cn3c4ccccc4c5ccccc35)CC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I18 compound treatment 661164.0 191000.0 0.39 692132.0 212000.0 0.46 0.6035 0.9972 1981094 ChemDiv1_024482 N=c1c(C#N)cnc2sc3ccccc3n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I19 compound treatment 649728.0 180000.0 0.37 703833.0 224000.0 0.48 0.6047 0.9914 1981095 ChemDiv1_024483 OC(CN1C2=NCCN2c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I20 compound treatment 694538.0 225000.0 0.46 706533.0 226000.0 0.49 0.6742 0.9996 1660774 ChemDiv1_024484 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6cnnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I21 compound treatment 704255.0 234000.0 0.48 709781.0 230000.0 0.5 0.6934 0.9999 1981096 ChemDiv1_024485 OC(CN1C2=NCCN2c3ccccc13)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I22 compound treatment 665146.0 195000.0 0.4 707436.0 227000.0 0.49 0.6327 0.9951 1364217 ChemDiv1_024486 O=c1c2c(nc3SC(Cn31)C#N)-c4ccccc4CC52CCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I23 mock treatment 702644.0 233000.0 0.48 681223.0 201000.0 0.43 0.6473 0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 I24 mock treatment 213873.0 -256000.0 -0.53 217423.0 -263000.0 -0.57 -0.7759 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J01 compound treatment 654718.0 185000.0 0.38 616574.0 136000.0 0.3 0.4784 0.9919 1709239 ChemDiv1_024487 CCCSc1nnc2n(Cc3ccc(OC)cc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J02 compound treatment 664936.0 195000.0 0.4 665619.0 185000.0 0.4 0.5684 1.0 1372574 ChemDiv1_024488 COc1ccc(C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J03 compound treatment 697112.0 227000.0 0.47 675856.0 196000.0 0.42 0.631 0.9987 1981097 ChemDiv1_024489 COc1ccc(/C=N/c2c(C)n(C)n(c3ccccc3)c2=O)cc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J04 compound treatment 680479.0 211000.0 0.43 627388.0 147000.0 0.32 0.5326 0.9883 1119413 ChemDiv1_024490 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccc(F)cc3)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J05 compound treatment 756572.0 287000.0 0.59 736856.0 257000.0 0.56 0.8112 0.9995 1499533 ChemDiv1_024491 Clc1ccc(cc1)C2NC(=O)c3c4CCCCc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J06 compound treatment 736356.0 266000.0 0.55 698242.0 218000.0 0.47 0.7226 0.9971 1513046 ChemDiv1_024492 COc1ccc(cc1OC)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J07 compound treatment 703197.0 233000.0 0.48 702204.0 222000.0 0.48 0.6803 1.0 1934131 ChemDiv1_024493 CC(=O)c1oc2ccc3c(C)cc(=O)oc3c2c1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J08 compound treatment 705448.0 236000.0 0.49 701394.0 221000.0 0.48 0.6823 1.0 1607850 ChemDiv1_024494 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Cl)c3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J09 compound treatment 793269.0 323000.0 0.67 1265662.0 785000.0 1.7 1.6741 0.9166 1981098 ChemDiv1_024495 CC1(C)Cc2ccccc2C3=CC(=O)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J10 compound treatment 718923.0 249000.0 0.51 701169.0 221000.0 0.48 0.7016 0.9993 1227307 ChemDiv1_024496 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(Cl)cc3)c4cccc(Oc5ccccc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J11 compound treatment 697934.0 228000.0 0.47 716042.0 236000.0 0.51 0.6937 0.9992 1981099 ChemDiv1_024497 CCOC(=O)C1=C2N(C(=O)C1=O)C(C)(C)Cc3cc(OC)c(OC)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J12 compound treatment 757528.0 288000.0 0.59 676301.0 196000.0 0.42 0.7199 0.9864 1981100 ChemDiv1_024498 Cc1ccc(cc1)c2nc3sc(=Cc4ccc(OCc5ccccc5)cc4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J13 compound treatment 741732.0 272000.0 0.56 712474.0 232000.0 0.5 0.7522 0.9985 1202846 ChemDiv1_024499 Cc1csc2c(=O)n3CCCCCc3nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J14 compound treatment 730249.0 260000.0 0.54 728199.0 248000.0 0.54 0.7595 1.0 1397103 ChemDiv1_024500 Cc1nn2c(=O)c(=Cc3ccc(OCc4ccccc4)cc3)sc2nc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J15 compound treatment 762122.0 292000.0 0.6 736963.0 257000.0 0.56 0.8195 0.9992 1981101 ChemDiv1_024501 Cc1ccc(cc1C)C(=O)N/C(=C\c2ccco2)/C(=O)NCCCn3ccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J16 compound treatment 720706.0 251000.0 0.52 701306.0 221000.0 0.48 0.7044 0.9992 1671283 ChemDiv1_024502 CCOC(=O)c1cnc2ccc(OCC)cc2c1Nc3cccc(c3)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J17 compound treatment 764204.0 294000.0 0.61 733407.0 253000.0 0.55 0.8171 0.9987 1981102 ChemDiv1_024503 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)c(Cl)c2)C#N)c3ccncc3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J18 compound treatment 726456.0 257000.0 0.53 722291.0 242000.0 0.52 0.7449 1.0 1358362 ChemDiv1_024504 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J19 compound treatment 2157446.0 1690000.0 3.48 1786962.0 1310000.0 2.83 4.4632 0.9947 1981103 ChemDiv1_024505 CN(/C=C/C=C/C=C/C1=[N+](C)c2ccccc2C1(C)C)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J20 compound treatment 667138.0 197000.0 0.41 675761.0 196000.0 0.42 0.5871 0.9998 1190777 ChemDiv1_024506 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(CC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J21 compound treatment 734355.0 264000.0 0.55 726073.0 246000.0 0.53 0.7623 0.9999 1670730 ChemDiv1_024507 COc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccccc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J22 compound treatment 715368.0 245000.0 0.51 722951.0 243000.0 0.53 0.7298 0.9998 1981104 ChemDiv1_024508 Fc1ccccc1COc2ccc(/C=C\3/C(=N)N4C(=CSC4=NC3=O)c5ccccc5)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J23 mock treatment 712232.0 242000.0 0.5 675525.0 195000.0 0.42 0.6526 0.9965 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 J24 mock treatment 239508.0 -230000.0 -0.48 255770.0 -224000.0 -0.49 -0.6798 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K01 compound treatment 623687.0 154000.0 0.32 595453.0 115000.0 0.25 0.4008 0.9928 1170666 ChemDiv1_024509 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(SC)nc(=O)c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K02 compound treatment 634175.0 164000.0 0.34 640101.0 160000.0 0.35 0.4845 1.0 1981105 ChemDiv1_024510 Cc1nc2c3cc4COC(C)(C)Cc4nc3sc2c(=O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K03 compound treatment 629541.0 160000.0 0.33 678842.0 199000.0 0.43 0.537 0.9914 1981106 ChemDiv1_024511 c1csc(c1)c2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K04 compound treatment 654230.0 184000.0 0.38 628083.0 148000.0 0.32 0.4953 0.9963 1251072 ChemDiv1_024512 COc1ccc(cc1OC)C2(CNC(=O)CC(c3ccccc3)c4ccccc4O)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K05 compound treatment 643919.0 174000.0 0.36 664871.0 185000.0 0.4 0.5366 0.9986 1981107 ChemDiv1_024513 CC(C)CCOCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K06 compound treatment 691517.0 222000.0 0.46 698499.0 218000.0 0.47 0.6575 0.9999 1943235 ChemDiv1_024514 Cc1ccc2nc3c(N)c(Cl)cc4C(=O)c5ccccc5-c(c2c1)c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K07 compound treatment 681059.0 211000.0 0.44 691171.0 211000.0 0.46 0.6311 0.9997 1690738 ChemDiv1_024515 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K08 compound treatment 677283.0 207000.0 0.43 672807.0 193000.0 0.42 0.5974 0.9999 1146719 ChemDiv1_024516 CCOCc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K09 compound treatment 719523.0 250000.0 0.52 699654.0 219000.0 0.47 0.7002 0.9992 1271093 ChemDiv1_024517 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccccc2)C#N)c3ccco3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K10 compound treatment 652002.0 182000.0 0.38 685710.0 205000.0 0.44 0.5803 0.9965 1981108 ChemDiv1_024518 CCCCCCc1cc2c3CCCCc3c(=O)oc2cc1OCC(=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K11 compound treatment 684130.0 214000.0 0.44 677316.0 197000.0 0.43 0.6143 0.9998 1417811 ChemDiv1_024519 Oc1ccc(cc1)c2csc(n2)C(=C3CCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K12 compound treatment 639961.0 170000.0 0.35 606183.0 126000.0 0.27 0.441 0.9922 1336463 ChemDiv1_024520 CCOC(=O)C(C)Oc1cc2oc(=O)c3CCCCc3c2cc1CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K13 compound treatment 695289.0 225000.0 0.47 670578.0 190000.0 0.41 0.6203 0.9982 1981109 ChemDiv1_024521 CC1CCC/C(=C(\C#N)/c2nc(cs2)c3ccccc3)/C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K14 compound treatment 692436.0 223000.0 0.46 680483.0 200000.0 0.43 0.6313 0.9996 1297807 ChemDiv1_024522 C[N+]1(CCCC2CN3C(CCCC3=O)C4CCC1)C24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K15 compound treatment 694828.0 225000.0 0.46 660232.0 180000.0 0.39 0.6038 0.9962 1222284 ChemDiv1_024523 Cc1cc2NC(=O)CC(c3cccc(Cl)c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K16 compound treatment 686988.0 217000.0 0.45 674179.0 194000.0 0.42 0.6137 0.9995 1981110 ChemDiv1_024524 COc1ccc(cc1)c2nc3cccc4cccc([nH]2)c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K17 compound treatment 720522.0 251000.0 0.52 691596.0 211000.0 0.46 0.6893 0.9981 1520252 ChemDiv1_024525 OC(CN1CCN(Cc2ccc(Cl)cc2Cl)CC1)Cn3c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K18 compound treatment 633338.0 163000.0 0.34 641126.0 161000.0 0.35 0.4848 0.9999 1981111 ChemDiv1_024526 CCC[B-]1(CCC)[NH+]=C(N=C2Nc3ccccc3N21)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K19 compound treatment 702332.0 232000.0 0.48 727706.0 247000.0 0.54 0.718 0.9985 1981112 ChemDiv1_024527 CC(C)(C)C(O)CN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K20 compound treatment 676187.0 206000.0 0.43 692510.0 212000.0 0.46 0.626 0.9993 1981113 ChemDiv1_024528 O=c1c2c(nc3SC(Cn31)c4ccccc4)-c5ccccc5CC62CCCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K21 compound treatment 693859.0 224000.0 0.46 722167.0 242000.0 0.52 0.6972 0.9981 1510601 ChemDiv1_024529 Clc1ccc(Cn2cnc3sc4CCCCc4c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K22 compound treatment 689246.0 219000.0 0.45 654310.0 174000.0 0.38 0.5866 0.9958 1557549 ChemDiv1_024530 CC1(C)Cc2ccccc2-c3nc4SC(Cn4c(=O)c31)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K23 mock treatment 683684.0 214000.0 0.44 691413.0 211000.0 0.46 0.6353 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 K24 mock treatment 211381.0 -259000.0 -0.53 246492.0 -234000.0 -0.51 -0.7351 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L01 compound treatment 682997.0 213000.0 0.44 615092.0 135000.0 0.29 0.5174 0.9801 1981114 ChemDiv1_024531 CCCCSc1nnc2n(Cc3ccc(OC)cc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L02 compound treatment 614532.0 145000.0 0.3 658561.0 178000.0 0.39 0.484 0.992 1981115 ChemDiv1_024532 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L03 compound treatment 690375.0 220000.0 0.46 679486.0 199000.0 0.43 0.6268 0.9996 1981116 ChemDiv1_024533 COc1cc(/C=N/c2c(C)n(C)n(c3ccccc3)c2=O)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L04 compound treatment 658822.0 189000.0 0.39 656428.0 176000.0 0.38 0.5454 0.9999 1193347 ChemDiv1_024534 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L05 compound treatment 659727.0 190000.0 0.39 674707.0 194000.0 0.42 0.5747 0.9994 1126026 ChemDiv1_024535 CCOC(=O)c1cnc2ccc(C)cc2c1Nc3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L06 compound treatment 690578.0 221000.0 0.46 647966.0 168000.0 0.36 0.5788 0.9937 1643541 ChemDiv1_024536 CC(C)c1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(C)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L07 compound treatment 730493.0 261000.0 0.54 702409.0 222000.0 0.48 0.7204 0.9984 1684758 ChemDiv1_024537 Cc1cc(=O)oc2c3c(c(oc3ccc12)C(=O)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L08 compound treatment 700568.0 231000.0 0.48 681002.0 201000.0 0.43 0.644 0.999 1981117 ChemDiv1_024538 COc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(Br)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L09 compound treatment 723233.0 253000.0 0.52 700207.0 220000.0 0.48 0.7064 0.9989 1981118 ChemDiv1_024539 COc1cc2CC(C)(C)N3C(=O)C(=O)C(=C3c2cc1OC)c4ccccc4Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L10 compound treatment 689639.0 220000.0 0.45 691869.0 212000.0 0.46 0.6446 1.0 1714113 ChemDiv1_024540 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3F)c4nnc(C)s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L11 compound treatment 714219.0 244000.0 0.5 685447.0 205000.0 0.44 0.6707 0.998 1981119 ChemDiv1_024541 CC1(C)Cc2ccccc2C3=C(C(=O)N4CCCC4)C(=O)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L12 compound treatment 735553.0 266000.0 0.55 706621.0 226000.0 0.49 0.7342 0.9984 1981120 ChemDiv1_024542 C=CCOc1ccc(C=c2sc3nc(nn3c2=O)c4cccnc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L13 compound treatment 695695.0 226000.0 0.47 672690.0 192000.0 0.42 0.6241 0.9984 1220029 ChemDiv1_024543 CCOC(=O)c1cc2c(N)c(oc2nc1C)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L14 compound treatment 732021.0 262000.0 0.54 677816.0 198000.0 0.43 0.685 0.9932 1387774 ChemDiv1_024544 COc1cc(C=c2sc3nc(=O)c(C)nn3c2=O)ccc1OCCC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L15 compound treatment 723629.0 254000.0 0.52 730558.0 250000.0 0.54 0.7535 0.9999 1981121 ChemDiv1_024545 Cc1ccc(cc1C)C(=O)N/C(=C\c2cccs2)/C(=O)NCCCn3ccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L16 compound treatment 718602.0 249000.0 0.51 680815.0 201000.0 0.43 0.67 0.9965 1728822 ChemDiv1_024546 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L17 compound treatment 687625.0 218000.0 0.45 719948.0 240000.0 0.52 0.6847 0.9974 1426255 ChemDiv1_024547 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Cl)cc2)C#N)c3ccncc3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L18 compound treatment 673540.0 204000.0 0.42 679492.0 199000.0 0.43 0.6022 0.9999 1580326 ChemDiv1_024548 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3cccc(c3)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L19 compound treatment 720012.0 250000.0 0.52 686856.0 207000.0 0.45 0.6813 0.9974 1525355 ChemDiv1_024549 CC1(C)CC(=O)C=C(C1)N2CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L20 compound treatment 713691.0 244000.0 0.5 695163.0 215000.0 0.47 0.6848 0.9992 1981122 ChemDiv1_024550 COc1ccc(C2NC(=S)NC(=C2C(=O)Nc3ccc(F)c(F)c3)C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L21 compound treatment 732449.0 263000.0 0.54 726746.0 246000.0 0.53 0.7605 1.0 1534782 ChemDiv1_024551 COc1ccc(C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccccc4)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L22 compound treatment 740128.0 270000.0 0.56 702123.0 222000.0 0.48 0.734 0.9972 1981123 ChemDiv1_024552 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCc5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L23 mock treatment 697016.0 227000.0 0.47 713427.0 233000.0 0.5 0.6884 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 L24 mock treatment 207925.0 -262000.0 -0.54 229633.0 -251000.0 -0.54 -0.7659 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M01 compound treatment 637113.0 167000.0 0.35 607118.0 127000.0 0.27 0.4383 0.9936 1642306 ChemDiv1_024553 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(SCc5ccccc5)nc(=O)c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M02 compound treatment 629730.0 160000.0 0.33 639838.0 160000.0 0.35 0.4776 0.9997 1131737 ChemDiv1_024554 O=C(N1CCCC1)C2(CCOCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M03 compound treatment 659438.0 190000.0 0.39 669128.0 189000.0 0.41 0.5658 0.9998 1981124 ChemDiv1_024555 c1coc(c1)c2nc3c4c(c(oc4ncn3n2)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M04 compound treatment 632346.0 162000.0 0.34 640905.0 161000.0 0.35 0.483 0.9998 1776672 ChemDiv1_024556 COc1cc2C(=NCC3(CCCC3)c2cc1OC)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M05 compound treatment 659537.0 190000.0 0.39 656460.0 176000.0 0.38 0.5465 0.9999 1981125 ChemDiv1_024557 CC(C)CCOCC1CC2(CC(C)(OC2=O)c3csc(NCC=C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M06 compound treatment 666451.0 197000.0 0.41 654372.0 174000.0 0.38 0.5534 0.9993 1175184 ChemDiv1_024558 CC(=O)OC1N=C(c2ccccc2)c3cc(C)ccc3NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M07 compound treatment 694543.0 225000.0 0.46 689857.0 210000.0 0.45 0.6487 0.9999 1390126 ChemDiv1_024559 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(Cl)cc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M08 compound treatment 684746.0 215000.0 0.44 668001.0 188000.0 0.41 0.601 0.999 1628379 ChemDiv1_024560 CC(C)c1ccc(cc1)C2OC(=NN2C(=O)C)c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M09 compound treatment 685472.0 216000.0 0.45 683694.0 203000.0 0.44 0.6261 1.0 1981126 ChemDiv1_024561 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc3ccccc23)C#N)c4ccco4)C(=O)Nc5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M10 compound treatment 650398.0 181000.0 0.37 650306.0 170000.0 0.37 0.5238 1.0 1516723 ChemDiv1_024562 CCN(CC)C(=O)COc1ccc2c(cc(=O)oc2c1C)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M11 compound treatment 712180.0 242000.0 0.5 673883.0 194000.0 0.42 0.65 0.9961 1282485 ChemDiv1_024563 CC1CCC(=C(C#N)c2nc(cs2)c3ccc(C)cc3)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M12 compound treatment 653172.0 183000.0 0.38 667424.0 187000.0 0.41 0.554 0.9994 1294132 ChemDiv1_024564 CCc1cc2c3CCCCc3c(=O)oc2cc1OC(C)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M13 compound treatment 696588.0 227000.0 0.47 729630.0 249000.0 0.54 0.7126 0.9975 1684280 ChemDiv1_024565 S=C1NC2(CCCC2)Nc3sc4CCCCc4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M14 compound treatment 668427.0 199000.0 0.41 688066.0 208000.0 0.45 0.6079 0.9989 1981127 ChemDiv1_024566 COCCCNC(=O)C(=O)Nc1cc(C)ccc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M15 compound treatment 700711.0 231000.0 0.48 698308.0 218000.0 0.47 0.6707 1.0 1708503 ChemDiv1_024567 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)c5ccccc5I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M16 compound treatment 623542.0 154000.0 0.32 617889.0 138000.0 0.3 0.4349 0.9995 1981128 ChemDiv1_024568 Brc1ccc(o1)c2nc3cccc4cccc([nH]2)c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M17 compound treatment 699669.0 230000.0 0.47 680560.0 200000.0 0.43 0.642 0.999 1981129 ChemDiv1_024569 COC(=O)C1(CCCCC1)C(=O)/C=C/c2ccc(Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M18 compound treatment 660783.0 191000.0 0.39 659524.0 179000.0 0.39 0.553 1.0 1330663 ChemDiv1_024570 CCOC(=O)C1Cn2c(S1)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M19 compound treatment 728876.0 259000.0 0.53 699086.0 219000.0 0.47 0.713 0.9982 1981130 ChemDiv1_024571 Clc1ccc(C(=O)CN2C3=NCCCN3c4ccccc24)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M20 compound treatment 682118.0 212000.0 0.44 676618.0 196000.0 0.43 0.6103 0.9999 1657389 ChemDiv1_024572 O=c1c2c(nc3SC(Cn31)c4ccccc4)-c5ccccc5CC62CCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M21 compound treatment 708333.0 238000.0 0.49 704264.0 224000.0 0.48 0.6909 1.0 1451269 ChemDiv1_024573 CC1CCc2c(C1)sc3ncn(Cc4ccccc4Cl)c(=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M22 compound treatment 715941.0 246000.0 0.51 672807.0 193000.0 0.42 0.6539 0.9952 1123112 ChemDiv1_024574 COc1ccc(Cn2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6cnnc26)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M23 mock treatment 705459.0 236000.0 0.49 664469.0 184000.0 0.4 0.6258 0.9951 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 M24 mock treatment 375011.0 -94900.0 -0.2 377461.0 -103000.0 -0.22 -0.2958 -0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N01 compound treatment 646624.0 177000.0 0.36 615756.0 136000.0 0.29 0.4654 0.9941 1981131 ChemDiv1_024575 CCCCCSc1nnc2n(Cc3ccc(OC)cc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N02 compound treatment 652121.0 182000.0 0.38 627169.0 147000.0 0.32 0.4909 0.9965 1706900 ChemDiv1_024576 COc1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(C)cc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N03 compound treatment 696021.0 226000.0 0.47 676998.0 197000.0 0.43 0.6312 0.9989 1981132 ChemDiv1_024577 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SC)nnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N04 compound treatment 636795.0 167000.0 0.34 651633.0 171000.0 0.37 0.5059 0.9993 1545864 ChemDiv1_024578 CC(C)c1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)C(=C2C(=O)c4ccccc4)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N05 compound treatment 664917.0 195000.0 0.4 678808.0 199000.0 0.43 0.5886 0.9995 1189841 ChemDiv1_024579 CC1(C)Cc2ccccc2-c3nc(c4ccccc4)n(Cc5ccccc5)c(=O)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N06 compound treatment 679515.0 210000.0 0.43 657990.0 178000.0 0.38 0.578 0.9983 1981133 ChemDiv1_024580 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N07 compound treatment 654727.0 185000.0 0.38 705444.0 225000.0 0.49 0.6145 0.9927 1450887 ChemDiv1_024581 Cc1ccc(cc1)C(=O)c2oc3ccc4c(C)cc(=O)oc4c3c2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N08 compound treatment 682813.0 213000.0 0.44 674472.0 194000.0 0.42 0.6081 0.9998 1630093 ChemDiv1_024582 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N09 compound treatment 698490.0 229000.0 0.47 712658.0 232000.0 0.5 0.6894 0.9995 1132392 ChemDiv1_024583 COc1cc2CC(C)(C)N=C(Cc3ccccc3Br)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N10 compound treatment 764210.0 294000.0 0.61 662012.0 182000.0 0.39 0.7078 0.9779 1272796 ChemDiv1_024584 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccc(Oc4ccccc4)c3)c5nnc(C)s5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N11 compound treatment 743607.0 274000.0 0.57 864562.0 384000.0 0.83 0.9877 0.9823 1981134 ChemDiv1_024585 O=C1C=C2N(C1=O)C3(CCCC3)Cc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N12 compound treatment 729724.0 260000.0 0.54 716958.0 237000.0 0.51 0.7416 0.9997 1981135 ChemDiv1_024586 CC(=O)Oc1ccccc1c2nc3sc(=Cc4ccc(OCC=C)cc4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N13 compound treatment 687326.0 217000.0 0.45 683757.0 204000.0 0.44 0.6289 1.0 1981136 ChemDiv1_024587 COc1ccc(cc1)n2cnc3nc(C)c(C(=O)C)c(c4ccccc4)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N14 compound treatment 705722.0 236000.0 0.49 693560.0 213000.0 0.46 0.6707 0.9996 1981137 ChemDiv1_024588 CC(C)CCOc1ccc(cc1)c2nn(cc2C=c3sc4nc(=O)c(Cc5ccccc5)nn4c3=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N15 compound treatment 710795.0 241000.0 0.5 732038.0 252000.0 0.54 0.737 0.999 1311413 ChemDiv1_024589 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccc(Cl)cc3)c4ccncc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N16 compound treatment 675647.0 206000.0 0.42 671997.0 192000.0 0.42 0.5938 0.9999 1674521 ChemDiv1_024590 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N17 compound treatment 736181.0 266000.0 0.55 674688.0 194000.0 0.42 0.6863 0.9913 1513618 ChemDiv1_024591 CC(=O)OCC1OC(C(OC(=O)C)C1OC(=O)C)n2ncc(=O)n(Cc3ccccc3)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N18 compound treatment 663975.0 194000.0 0.4 676666.0 196000.0 0.43 0.5839 0.9996 1487691 ChemDiv1_024592 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(cc3)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N19 compound treatment 701164.0 231000.0 0.48 711356.0 231000.0 0.5 0.6913 0.9997 1981138 ChemDiv1_024593 CCOCCOC(=O)C1=C(C)NC(=O)CC1c2cccc(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N20 compound treatment 700751.0 231000.0 0.48 669846.0 190000.0 0.41 0.6272 0.9972 1981139 ChemDiv1_024594 COc1ccc(OC)c(c1)C2NC(=S)NC(=C2C(=O)Nc3ccc(C)cc3C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N21 compound treatment 713877.0 244000.0 0.5 693087.0 213000.0 0.46 0.6819 0.999 1627599 ChemDiv1_024595 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccccc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N22 compound treatment 698631.0 229000.0 0.47 658749.0 178000.0 0.39 0.6071 0.995 1981140 ChemDiv1_024596 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N23 mock treatment 690390.0 221000.0 0.46 675497.0 195000.0 0.42 0.6207 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 N24 mock treatment 531469.0 61600.0 0.13 372917.0 -107000.0 -0.23 -0.0744 -0.2808 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O01 compound treatment 605293.0 135000.0 0.28 593577.0 113000.0 0.25 0.3711 0.9979 1431383 ChemDiv1_024597 CC(C)(C)C(=O)Oc1ccc2c3CCCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O02 compound treatment 632317.0 162000.0 0.34 613415.0 133000.0 0.29 0.4409 0.9972 1214169 ChemDiv1_024598 O=C(N1CCOCC1)C2(CCOCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O03 compound treatment 661835.0 192000.0 0.4 628565.0 148000.0 0.32 0.5072 0.9945 1981141 ChemDiv1_024599 COc1ccc(cc1)c2nc3c4c(c(oc4ncn3n2)c5ccc(OC)cc5)c6ccc(OC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O04 compound treatment 654324.0 184000.0 0.38 634433.0 154000.0 0.33 0.5052 0.9978 1981142 ChemDiv1_024600 O=C(CN1CCOCC1)NCC2(CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O05 compound treatment 613427.0 144000.0 0.3 605583.0 125000.0 0.27 0.4013 0.999 1981143 ChemDiv1_024601 CCCCCC1CC(CC(O)CO)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O06 compound treatment 639855.0 170000.0 0.35 621046.0 141000.0 0.3 0.4636 0.9975 1981144 ChemDiv1_024602 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(S)n42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O07 compound treatment 661644.0 192000.0 0.4 659623.0 179000.0 0.39 0.5544 1.0 1203674 ChemDiv1_024603 CC(=O)N1C(CC(=Nc2ccccc12)c3ccc(I)cc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O08 compound treatment 639041.0 169000.0 0.35 663488.0 183000.0 0.4 0.5274 0.998 1210286 ChemDiv1_024604 CCN1C2C(N(CC)C1=O)N(CC)C(=O)N2CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O09 compound treatment 688896.0 219000.0 0.45 789170.0 309000.0 0.67 0.7925 0.9818 1673845 ChemDiv1_024605 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccncc2)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O10 compound treatment 616866.0 147000.0 0.3 624219.0 144000.0 0.31 0.4349 0.9999 1601719 ChemDiv1_024606 CCN(CC)C(=O)COc1ccc2c3CCCCc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O11 compound treatment 681040.0 211000.0 0.44 659740.0 179000.0 0.39 0.5829 0.9984 1981145 ChemDiv1_024607 Brc1ccc(cc1)c2csc(n2)C(=C3CCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O12 compound treatment 629328.0 159000.0 0.33 638217.0 158000.0 0.34 0.4745 0.9998 1372007 ChemDiv1_024608 CCc1cc2c(cc(=O)oc2cc1OCC(=O)N)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O13 compound treatment 701490.0 232000.0 0.48 688375.0 208000.0 0.45 0.6566 0.9996 1194811 ChemDiv1_024609 S=C1NC2(CCCCC2)Nc3sc4CCCCc4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O14 compound treatment 627785.0 158000.0 0.33 619941.0 140000.0 0.3 0.4443 0.9993 1618767 ChemDiv1_024610 COc1ccc(cc1OC)C2(CNC(=O)C3(CCCC3)c4ccccc4)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O15 compound treatment 682504.0 213000.0 0.44 698996.0 219000.0 0.47 0.6451 0.9993 1363962 ChemDiv1_024611 OC(CN1CCN(Cc2ccc(Cl)cc2)CC1)Cn3c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O16 compound treatment 678435.0 209000.0 0.43 658740.0 178000.0 0.39 0.5776 0.9985 1128756 ChemDiv1_024612 COc1ccc(cc1)c2nnc(SCC(=O)N3CCN(C)CC3)nc2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O17 compound treatment 713708.0 244000.0 0.5 669633.0 189000.0 0.41 0.6457 0.9948 1981146 ChemDiv1_024613 COC(=O)C1(CCCCC1)C(=O)/C=C/c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O18 compound treatment 645099.0 175000.0 0.36 650644.0 170000.0 0.37 0.5165 1.0 1144954 ChemDiv1_024614 CCOC(=O)C1Cn2c(S1)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O19 compound treatment 680224.0 210000.0 0.43 665670.0 185000.0 0.4 0.5908 0.9992 1981147 ChemDiv1_024615 Brc1cccc(c1)C(=O)CN2C3=NCCN3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O20 compound treatment 672648.0 203000.0 0.42 665510.0 185000.0 0.4 0.5795 0.9998 1182245 ChemDiv1_024616 CCC1(C)Cc2ccccc2-c3nc4SC(Cn4c(=O)c31)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O21 compound treatment 699999.0 230000.0 0.48 680123.0 200000.0 0.43 0.6418 0.9989 1664846 ChemDiv1_024617 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)N4CCN(C)CC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O22 compound treatment 671141.0 201000.0 0.42 662225.0 182000.0 0.39 0.5723 0.9996 1981148 ChemDiv1_024618 Cc1ccccc1n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6cnnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O23 mock treatment 669646.0 200000.0 0.41 648018.0 168000.0 0.36 0.5483 0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 O24 mock treatment 409327.0 -60600.0 -0.13 424448.0 -55800.0 -0.12 -0.1738 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P01 compound treatment 631110.0 161000.0 0.33 608039.0 128000.0 0.28 0.4309 0.9958 1981149 ChemDiv1_024619 Cc1cccc(c1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6cnnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P02 compound treatment 623646.0 154000.0 0.32 607955.0 128000.0 0.28 0.4199 0.9976 1487200 ChemDiv1_024620 COc1ccc(C2N(CCCN(C)C)C(=O)C(=C2C(=O)c3ccccc3)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P03 compound treatment 623477.0 154000.0 0.32 622838.0 143000.0 0.31 0.4424 0.9999 1450054 ChemDiv1_024621 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCC5)n6c(S)nnc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P04 compound treatment 619340.0 149000.0 0.31 605472.0 125000.0 0.27 0.4098 0.9979 1178330 ChemDiv1_024622 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccccc3F)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P05 compound treatment 637826.0 168000.0 0.35 620994.0 141000.0 0.3 0.4605 0.9979 1981150 ChemDiv1_024623 CCOc1ccccc1NC(=O)c2cc(ccc2N3CCCCC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P06 compound treatment 666792.0 197000.0 0.41 625607.0 145000.0 0.31 0.5099 0.992 1405550 ChemDiv1_024624 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccccc3F)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P07 compound treatment 662557.0 193000.0 0.4 615627.0 135000.0 0.29 0.4884 0.9887 1170390 ChemDiv1_024625 Cc1cc(=O)oc2c3c(c(oc3ccc12)C(=O)c4ccc(Cl)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P08 compound treatment 679448.0 210000.0 0.43 643010.0 163000.0 0.35 0.555 0.9948 1557538 ChemDiv1_024626 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nnc(C)s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P09 compound treatment 630488.0 161000.0 0.33 613478.0 133000.0 0.29 0.4383 0.9976 1981151 ChemDiv1_024627 CC1(C)Cc2c(ccc3ccccc23)C4=CC(=O)C(=O)N41 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P10 compound treatment 691993.0 222000.0 0.46 648515.0 168000.0 0.36 0.5817 0.9935 1362899 ChemDiv1_024628 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccc(F)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P11 compound treatment 695098.0 225000.0 0.46 641032.0 161000.0 0.35 0.5748 0.9898 1226906 ChemDiv1_024629 CCCC1=NC(C)(C)Cc2cc(OC)c(OC)cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P12 compound treatment 693018.0 223000.0 0.46 650022.0 170000.0 0.37 0.5855 0.9937 1715771 ChemDiv1_024630 COc1cc(C=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)ccc1OCCC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P13 compound treatment 661336.0 191000.0 0.4 607347.0 127000.0 0.28 0.474 0.9843 1689780 ChemDiv1_024631 CCOC(=O)C1CCc2oc3ccc(O)cc3c2C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P14 compound treatment 649021.0 179000.0 0.37 617407.0 137000.0 0.3 0.4714 0.9941 1981152 ChemDiv1_024632 CCOc1ccc(cc1)C2(CCCCC2)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P15 compound treatment 657265.0 187000.0 0.39 663925.0 184000.0 0.4 0.5546 0.9999 1690622 ChemDiv1_024633 COc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P16 compound treatment 701449.0 232000.0 0.48 657515.0 177000.0 0.38 0.6093 0.9941 1458435 ChemDiv1_024634 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P17 compound treatment 680728.0 211000.0 0.44 666010.0 186000.0 0.4 0.5921 0.9992 1344011 ChemDiv1_024635 COc1ccc(Cn2c(=O)cnn(C3OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C3OC(=O)C)c2=O)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P18 compound treatment 929551.0 460000.0 0.95 677164.0 197000.0 0.43 0.9723 0.9347 1499865 ChemDiv1_024636 CCOC(=O)c1ccc(Nc2c(cnc3c(C)cc(C)cc23)C(=O)OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P19 compound treatment 686104.0 216000.0 0.45 659168.0 179000.0 0.39 0.5894 0.9975 1981153 ChemDiv1_024637 CC1(C)Cc2c(C#N)c(NC(=S)NC(=O)c3ccccc3)sc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P20 compound treatment 692236.0 222000.0 0.46 646399.0 166000.0 0.36 0.5788 0.9927 1981154 ChemDiv1_024638 COc1ccc(C2NC(=S)NC(=C2C(=O)Nc3ccc(C)cc3C)C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P21 compound treatment 646127.0 176000.0 0.36 650670.0 170000.0 0.37 0.5181 1.0 1289277 ChemDiv1_024639 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccc(Cl)cc3)C(=O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P22 compound treatment 671847.0 202000.0 0.42 621822.0 142000.0 0.31 0.5115 0.9885 1981155 ChemDiv1_024640 Cc1ccc(OCCOc2ccc(/C=C\3/C(=N)N4C(=CSC4=NC3=O)c5ccccc5)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P23 mock treatment 637602.0 168000.0 0.35 627205.0 147000.0 0.32 0.4697 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.656 P24 mock treatment 182050.0 -288000.0 -0.59 465863.0 -14400.0 -0.03 -0.4422 -0.7431 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A01 compound treatment 636790.0 156000.0 0.32 572160.0 107000.0 0.23 0.3914 0.9867 1981156 ChemDiv1_024641 Cc1ccc(OCCOc2ccc(/C=C\3/C(=N)N4C(=CSC4=NC3=O)c5ccccc5)cc2)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A02 compound treatment 693744.0 213000.0 0.44 640636.0 175000.0 0.38 0.5793 0.9973 1778635 ChemDiv1_024642 CCOc1ccc(cc1)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A03 compound treatment 4771871.0 4290000.0 8.86 598265.0 133000.0 0.29 6.4672 0.7297 1981157 ChemDiv1_024643 CCOc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A04 compound treatment 707191.0 227000.0 0.47 687733.0 222000.0 0.48 0.671 0.9999 1981158 ChemDiv1_024644 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2cccc3ccccc23)c4ccc(Br)cc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A05 compound treatment 676230.0 196000.0 0.4 635168.0 170000.0 0.37 0.5454 0.9989 1981159 ChemDiv1_024645 CC[n+]1c(/C=C/2\Sc3ccccc3N2CCC(=O)O)sc4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A06 compound treatment 682364.0 202000.0 0.42 645297.0 180000.0 0.39 0.5698 0.9994 1981160 ChemDiv1_024646 Fc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5cc(Cl)ccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A07 compound treatment 707040.0 226000.0 0.47 635762.0 170000.0 0.37 0.5912 0.9931 1259288 ChemDiv1_024647 COc1ccc(cc1)c2nnc(SCCN3CCCCC3)nc2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A08 compound treatment 830223.0 350000.0 0.72 782959.0 318000.0 0.69 0.9963 0.9997 1981161 ChemDiv1_024648 COc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A09 compound treatment 706094.0 225000.0 0.47 650473.0 185000.0 0.4 0.6124 0.9972 1219596 ChemDiv1_024649 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCC(C)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A10 compound treatment 772439.0 292000.0 0.6 742514.0 277000.0 0.6 0.8501 1.0 1981162 ChemDiv1_024650 Cc1ccc(cc1)C(=O)[C@H]2[C@H](c3ccccc3F)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A11 compound treatment 669187.0 189000.0 0.39 644324.0 179000.0 0.39 0.5491 1.0 1310189 ChemDiv1_024651 CCCN(CCC)C(=O)c1c(NC(=O)c2cccnc2)sc3CCCCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A12 compound treatment 665717.0 185000.0 0.38 628963.0 164000.0 0.35 0.5205 0.9993 1259846 ChemDiv1_024652 COC(=O)CON1C(N(CC1=O)C(=O)c2ccccc2)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A13 compound treatment 688311.0 208000.0 0.43 607522.0 142000.0 0.31 0.5207 0.9868 1653466 ChemDiv1_024653 CC1CCCCC1NC(=O)c2cc3ccccc3o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A14 compound treatment 1457893.0 977000.0 2.02 1333039.0 868000.0 1.88 2.7544 0.9994 1981163 ChemDiv1_024654 O=C([C@@H]1[C@@H]2C3COC(O3)C(=O)[C@H]2[C@@H]4C=Cc5ccccc5N14)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A15 compound treatment 686593.0 206000.0 0.43 630965.0 166000.0 0.36 0.5541 0.9964 1981164 ChemDiv1_024655 OC/1C2CCN(CC2)\C1=C/c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A16 compound treatment 681588.0 201000.0 0.41 628787.0 163000.0 0.35 0.5434 0.9969 1981165 ChemDiv1_024656 CCCCOc1ccc(cc1)C(=O)NCCCCOc2ccc(cc2C(C)(C)CC)C(C)(C)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A17 compound treatment 684868.0 204000.0 0.42 638805.0 173000.0 0.38 0.5635 0.9983 1981166 ChemDiv1_024657 CN(C)Cc1c(O)ccc2oc(CSc3ccccc3)c(C(=O)C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A18 compound treatment 710465.0 230000.0 0.47 639419.0 174000.0 0.38 0.6018 0.9935 1242762 ChemDiv1_024658 NC1=C(C#N)C(C(=c2sc(=Cc3ccc(Cl)cc3)c(=O)n12)C#N)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A19 compound treatment 671043.0 190000.0 0.39 611817.0 146000.0 0.32 0.5021 0.9943 1981167 ChemDiv1_024659 CCCc1c(C)c2c(C)n[nH]c2oc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A20 compound treatment 661699.0 181000.0 0.37 591790.0 126000.0 0.27 0.4578 0.9883 1981168 ChemDiv1_024660 COc1cc(ccc1O)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A21 compound treatment 725806.0 245000.0 0.51 621926.0 157000.0 0.34 0.5975 0.981 1981169 ChemDiv1_024661 Ic1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A22 compound treatment 640033.0 159000.0 0.33 578017.0 113000.0 0.24 0.4051 0.9891 1981170 ChemDiv1_024662 NC=C1C(=O)N(C(=S)N(C1=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A23 mock treatment 616830.0 136000.0 0.28 547550.0 82200.0 0.18 0.3246 0.9757 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 A24 mock treatment 229926.0 -251000.0 -0.52 240262.0 -225000.0 -0.49 -0.7105 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B01 compound treatment 622508.0 142000.0 0.29 575909.0 111000.0 0.24 0.3763 0.995 1348040 ChemDiv1_024663 CCOC(=O)C1=C(N)SC(C1c2ccccc2)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B02 compound treatment 660824.0 180000.0 0.37 619046.0 154000.0 0.33 0.4982 0.9985 1981171 ChemDiv1_024664 CCOc1cc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B03 compound treatment 880577.0 400000.0 0.83 823191.0 358000.0 0.77 1.1314 0.9995 1981172 ChemDiv1_024665 NC1=C(C#N)C2=CCCC[C@H]2[C@H](c3ccc(F)cc3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B04 compound treatment 666373.0 186000.0 0.38 639232.0 174000.0 0.38 0.5372 1.0 1981173 ChemDiv1_024666 CSC1=N/C(=N\c2cccc(c2)C(F)(F)F)/C3(CCCCC3)N1c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B05 compound treatment 1931446.0 1450000.0 2.99 1944287.0 1480000.0 3.2 4.3811 0.9994 1981174 ChemDiv1_024667 Cc1ccc(cc1)S(=O)(=O)Oc2ccc3ccccc3c2/C=N/NC(=O)C(=O)N\N=C\c4c(OS(=O)(=O)c5ccc(C)cc5)ccc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B06 compound treatment 694818.0 214000.0 0.44 654620.0 189000.0 0.41 0.6023 0.9993 1981175 ChemDiv1_024668 CCN(CC)c1ccc(/C=N/c2c(C)n(C)n(c3ccccc3)c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B07 compound treatment 717490.0 237000.0 0.49 699679.0 234000.0 0.51 0.7043 0.9998 1981176 ChemDiv1_024669 [O-][N+](=O)c1ccc(cc1)N2C(=O)C3C(C4C(=O)CC3c5ccccc45)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B08 compound treatment 721530.0 241000.0 0.5 698752.0 233000.0 0.51 0.7088 1.0 1981177 ChemDiv1_024670 Cc1ccc(/N=C\C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B09 compound treatment 1224845.0 744000.0 1.54 1205535.0 740000.0 1.6 2.2191 0.9998 1981178 ChemDiv1_024671 CC(C)c1ccc(cc1)[C@H]2[C@@H]3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B10 compound treatment 694453.0 214000.0 0.44 693630.0 228000.0 0.49 0.6614 0.9984 1981179 ChemDiv1_024672 ClCCC(=O)NCC1(CCCC1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B11 compound treatment 728644.0 248000.0 0.51 717298.0 252000.0 0.55 0.7476 0.9995 1555896 ChemDiv1_024673 O=c1[nH]c(Cc2ccccc2)nc3-c4ccccc4CC5(CCCC5)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B12 compound treatment 717021.0 236000.0 0.49 691696.0 226000.0 0.49 0.6914 1.0 1536438 ChemDiv1_024674 O=C1N(CCN2CCCc3ccccc23)C(=O)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B13 compound treatment 828861.0 348000.0 0.72 763074.0 298000.0 0.64 0.9639 0.9985 1981180 ChemDiv1_024675 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccc4ccccc34)C(C#N)(C#N)[C@H]5C=Cc6cc(Cl)ccc6N25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B14 compound treatment 722800.0 242000.0 0.5 699502.0 234000.0 0.51 0.7118 1.0 1981181 ChemDiv1_024676 O=C1CC(C#N)C2(CCCCC2)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B15 compound treatment 725998.0 245000.0 0.51 733624.0 268000.0 0.58 0.7687 0.9977 1981182 ChemDiv1_024677 COc1cccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B16 compound treatment 704877.0 224000.0 0.46 669155.0 204000.0 0.44 0.6392 0.9997 1981183 ChemDiv1_024678 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5ccc(cc5)[N+](=O)[O-])ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B17 compound treatment 729482.0 249000.0 0.51 698287.0 233000.0 0.5 0.7197 1.0 1981184 ChemDiv1_024679 O=C(N/N=C/c1cn(nc1c2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B18 compound treatment 679745.0 199000.0 0.41 675118.0 210000.0 0.45 0.6116 0.9988 1608424 ChemDiv1_024680 Cc1ccc(NC(=O)Cc2c(Sc3ccccc3)c4cc(C)ccc4n2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B19 compound treatment 714574.0 234000.0 0.48 679740.0 214000.0 0.46 0.6695 0.9998 1471426 ChemDiv1_024681 Cc1nc2-c3ccccc3CC4(CCCCC4)c2c(=S)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B20 compound treatment 680790.0 200000.0 0.41 661863.0 197000.0 0.43 0.5929 0.9999 1389276 ChemDiv1_024682 CC1CN(CCC1(OC(=O)C)c2ccccc2)C3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B21 compound treatment 731228.0 251000.0 0.52 659258.0 194000.0 0.42 0.6625 0.9946 1645705 ChemDiv1_024683 Clc1ccc(cc1)C2N(CCN2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B22 compound treatment 669224.0 189000.0 0.39 624106.0 159000.0 0.34 0.5182 0.9981 1981185 ChemDiv1_024684 CC1(C)CC(=O)C2=C(C1)C(Nc3ccc4ccccc4c23)c5ccc(o5)c6cccc(c6)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B23 mock treatment 684601.0 204000.0 0.42 633031.0 168000.0 0.36 0.5543 0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 B24 mock treatment 241675.0 -239000.0 -0.49 228711.0 -237000.0 -0.51 -0.711 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C01 compound treatment 656215.0 176000.0 0.36 594009.0 129000.0 0.28 0.4532 0.9915 1981186 ChemDiv1_024685 CCOc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C02 compound treatment 730354.0 250000.0 0.52 751288.0 286000.0 0.62 0.8021 0.9959 1981187 ChemDiv1_024686 Clc1ccc([C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C03 compound treatment 698479.0 218000.0 0.45 677683.0 212000.0 0.46 0.6429 0.9999 1981188 ChemDiv1_024687 Ic1ccc(OC2CCCCO2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C04 compound treatment 732060.0 251000.0 0.52 702133.0 237000.0 0.51 0.7293 1.0 1981189 ChemDiv1_024688 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4ccc(Br)cc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C05 compound treatment 711791.0 231000.0 0.48 698742.0 233000.0 0.51 0.6946 0.9996 1553583 ChemDiv1_024689 CC1(CC2C(C(=O)N3CCOCC3)C(=O)N1)Oc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C06 compound treatment 761251.0 281000.0 0.58 750126.0 285000.0 0.62 0.8454 0.9995 1981190 ChemDiv1_024690 Fc1ccc(cc1)[C@H]2[C@@H](N3[C@@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C07 compound treatment 715937.0 235000.0 0.49 708364.0 243000.0 0.53 0.7153 0.9992 1156114 ChemDiv1_024691 CC(C)C1C(NC(CC1(C)O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C08 compound treatment 839979.0 359000.0 0.74 783932.0 319000.0 0.69 1.0121 0.9993 1981191 ChemDiv1_024692 CC(=O)[C@@H]1[C@@H](c2ccccc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C09 compound treatment 791558.0 311000.0 0.64 693196.0 228000.0 0.49 0.8025 0.9915 1332594 ChemDiv1_024693 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C10 compound treatment 723602.0 243000.0 0.5 705170.0 240000.0 0.52 0.7216 0.9999 1981192 ChemDiv1_024694 CC1=NN(C(=O)C21C(c3ccc(Cl)cc3Cl)C42C(=NN(C4=O)c5ccc(C)c(C)c5)C)c6ccc(C)c(C)c6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C11 compound treatment 754962.0 274000.0 0.57 762936.0 298000.0 0.64 0.8558 0.9979 1408119 ChemDiv1_024695 Cc1ccc(NC(=O)c2c(NC(=O)c3ccccc3F)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C12 compound treatment 726128.0 245000.0 0.51 720189.0 255000.0 0.55 0.7483 0.9991 1981193 ChemDiv1_024696 Cc1ccc(cc1)C(=O)[C@H]2[C@@H]3C4COC(O4)C(=O)[C@H]3[C@H]5N2C=Cc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C13 compound treatment 688685.0 208000.0 0.43 682857.0 218000.0 0.47 0.6365 0.9989 1981194 ChemDiv1_024697 Fc1ccc(cc1)c2cc(nc(Cl)n2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C14 compound treatment 755801.0 275000.0 0.57 711965.0 247000.0 0.53 0.779 0.9995 1981195 ChemDiv1_024698 CC(=O)C1=C(C)NC(=C(C#N)[C@@H]1c2ccccc2[N+](=O)[O-])SCC(=O)NC3(CC4CC5CC(C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C15 compound treatment 751751.0 271000.0 0.56 709786.0 244000.0 0.53 0.7698 0.9996 1428997 ChemDiv1_024699 CC(=O)NC1=C(O)CC(C)(C)CC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C16 compound treatment 785802.0 305000.0 0.63 697354.0 232000.0 0.5 0.8005 0.9937 1981196 ChemDiv1_024700 CC1(C)COP(=O)(OC1)C(Nc2ccc(Cl)cc2)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C17 compound treatment 772271.0 292000.0 0.6 738735.0 273000.0 0.59 0.8441 1.0 1609201 ChemDiv1_024701 CCCc1nc2sc3c(ncnc3c2c4CC(C)(C)OCc14)N5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C18 compound treatment 728056.0 247000.0 0.51 699385.0 234000.0 0.51 0.7193 1.0 1260698 ChemDiv1_024702 NC1=C(C#N)C(C(=c2sc(=Cc3ccc(F)cc3)c(=O)n12)C#N)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C19 compound treatment 726894.0 246000.0 0.51 686109.0 221000.0 0.48 0.6973 0.9995 1981197 ChemDiv1_024703 Cc1ccc(cc1C)C(=O)N/C(=C\c2cccs2)/C(=O)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C20 compound treatment 697293.0 217000.0 0.45 671538.0 206000.0 0.45 0.6318 1.0 1981198 ChemDiv1_024704 Brc1ccc(cc1)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C21 compound treatment 822636.0 342000.0 0.71 816360.0 351000.0 0.76 1.0364 0.9993 1742378 ChemDiv1_024705 Clc1ccc(C2C(N3C=Cc4ccccc4C3C2(C#N)C#N)C(=O)c5ccccc5)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C22 compound treatment 794347.0 314000.0 0.65 780786.0 315000.0 0.68 0.9406 0.9996 1476167 ChemDiv1_024706 Clc1cccc(OC(=O)C2C(c3ccccc3)C(C#N)(C#N)C4C=Cc5ccccc5N24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C23 mock treatment 711550.0 231000.0 0.48 649703.0 184000.0 0.4 0.6192 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 C24 mock treatment 213423.0 -267000.0 -0.55 234104.0 -231000.0 -0.5 -0.744 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D01 compound treatment 639274.0 159000.0 0.33 594832.0 129000.0 0.28 0.4297 0.997 1981199 ChemDiv1_024707 Cc1cc(C)c(cc1[N+](=O)[O-])c2ccc(/C=N/c3c(nc4ccccn34)c5ccco5)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D02 compound treatment 667377.0 187000.0 0.39 626973.0 162000.0 0.35 0.5199 0.9988 1981200 ChemDiv1_024708 Brc1cccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D03 compound treatment 689487.0 209000.0 0.43 647166.0 182000.0 0.39 0.5831 0.999 1981201 ChemDiv1_024709 [O-][N+](=O)c1ccccc1C(=O)Nc2ccc3-c4ccc(NC(=O)c5ccccc5[N+](=O)[O-])cc4S(=O)(=O)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D04 compound treatment 705769.0 225000.0 0.46 634784.0 169000.0 0.37 0.5879 0.9931 1981202 ChemDiv1_024710 COc1ccc(cc1)N2C(=N/C(=N\c3cccc(c3)C(F)(F)F)/C42CCCCC4)SC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D05 compound treatment 735150.0 254000.0 0.53 679644.0 214000.0 0.46 0.6994 0.9981 1981203 ChemDiv1_024711 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4cc(Br)c(O)c(Br)c4O)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D06 compound treatment 693370.0 213000.0 0.44 622395.0 157000.0 0.34 0.5508 0.992 1981204 ChemDiv1_024712 CCC(C)(C)c1ccc(OCCCCNC(=O)c2cccc(c2)C(=O)NCCCCOc3ccc(cc3C(C)(C)CC)C(C)(C)CC)c(c1)C(C)(C)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D07 compound treatment 750914.0 270000.0 0.56 703028.0 238000.0 0.51 0.7582 0.9992 1981205 ChemDiv1_024713 CCOc1ccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(OCC)cc6)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D08 compound treatment 752602.0 272000.0 0.56 693327.0 228000.0 0.49 0.7459 0.9979 1981206 ChemDiv1_024714 O=C1C2C(C(=O)N1c3ccccc3)C4(/C=N\c5ccccc5)c6ccccc6C2c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D09 compound treatment 750028.0 269000.0 0.56 714230.0 249000.0 0.54 0.7741 0.9999 1666797 ChemDiv1_024715 NNc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D10 compound treatment 739306.0 259000.0 0.53 684169.0 219000.0 0.47 0.7124 0.9982 1981207 ChemDiv1_024716 ClCC(=O)NCC1(CCCC1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D11 compound treatment 777572.0 297000.0 0.61 715825.0 250000.0 0.54 0.8167 0.9981 1981208 ChemDiv1_024717 CC(C)c1ccc(/C=N/c2c(C)n(C)n(c3ccccc3)c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D12 compound treatment 732738.0 252000.0 0.52 699147.0 234000.0 0.51 0.7258 0.9999 1981209 ChemDiv1_024718 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5cccc(c5)C(=O)O)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D13 compound treatment 846261.0 366000.0 0.75 783398.0 318000.0 0.69 1.0204 0.9989 1981210 ChemDiv1_024719 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D14 compound treatment 899771.0 419000.0 0.87 796484.0 331000.0 0.72 1.1185 0.9956 1981211 ChemDiv1_024720 Fc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D15 compound treatment 756246.0 276000.0 0.57 700864.0 236000.0 0.51 0.7627 0.9985 1374372 ChemDiv1_024721 CC(C)(C)C1CC=C2C(C1)C(c3ccccc3Cl)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D16 compound treatment 728672.0 248000.0 0.51 685680.0 220000.0 0.48 0.6992 0.9994 1981212 ChemDiv1_024722 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5cc(ccc5Cl)[N+](=O)[O-])ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D17 compound treatment 767242.0 287000.0 0.59 732389.0 267000.0 0.58 0.827 0.9999 1981213 ChemDiv1_024723 C=CCOc1ccc(cc1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D18 compound treatment 793250.0 313000.0 0.65 744152.0 279000.0 0.6 0.883 0.9994 1981214 ChemDiv1_024724 Cc1cccc[n+]1[C@@H]2[C@H](C(=C(S)N[C@]2(C)O)C#N)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D19 compound treatment 781976.0 301000.0 0.62 682635.0 217000.0 0.47 0.7724 0.9905 1981215 ChemDiv1_024725 CSCON1C(N(CC1=O)C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D20 compound treatment 691483.0 211000.0 0.44 702148.0 237000.0 0.51 0.6701 0.9967 1319275 ChemDiv1_024726 CC1CN(C)C(C)(C)CC1(OC(=O)C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D21 compound treatment 755092.0 274000.0 0.57 694303.0 229000.0 0.5 0.751 0.9978 1113525 ChemDiv1_024727 O=S1(=O)c2ccccc2-c3ccccc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D22 compound treatment 713111.0 232000.0 0.48 658471.0 193000.0 0.42 0.6349 0.9976 1981216 ChemDiv1_024728 Oc1c(Br)cc(Cl)cc1C(=O)Nc2cc(Cl)ccc2Oc3ccc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D23 mock treatment 703735.0 223000.0 0.46 664386.0 199000.0 0.43 0.6302 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 D24 mock treatment 237214.0 -243000.0 -0.5 231057.0 -234000.0 -0.51 -0.7139 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E01 compound treatment 620814.0 140000.0 0.29 599362.0 134000.0 0.29 0.4097 1.0 1981217 ChemDiv1_024729 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E02 compound treatment 770236.0 290000.0 0.6 736474.0 271000.0 0.59 0.8376 1.0 1981218 ChemDiv1_024730 Brc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E03 compound treatment 701026.0 220000.0 0.45 677360.0 212000.0 0.46 0.6461 1.0 1261940 ChemDiv1_024731 Oc1ccc(cc1)c2nc3ccccc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E04 compound treatment 755659.0 275000.0 0.57 742041.0 277000.0 0.6 0.8249 0.9996 1981219 ChemDiv1_024732 CCOc1ccc(cc1)C2C([n+]3ccc(C)cc3)C(O)(NC(=C2C#N)[C-](C#N)C#N)C4CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E05 compound treatment 739176.0 259000.0 0.53 687248.0 222000.0 0.48 0.717 0.9986 1125760 ChemDiv1_024733 Cc1cccc(NC(=O)C2C3CC(C)(NC2=O)Oc4ccccc34)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E06 compound treatment 709849.0 229000.0 0.47 712364.0 247000.0 0.53 0.7126 0.9981 1981220 ChemDiv1_024734 Clc1ccc2N3[C@@H]([C@@H](c4ccccc4I)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E07 compound treatment 754295.0 274000.0 0.56 724194.0 259000.0 0.56 0.7956 1.0 1925093 ChemDiv1_024735 Cc1ccsc1/C=C(\NC(=O)c2ccc(C)cc2)/C(=O)NCCCN3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E08 compound treatment 770391.0 290000.0 0.6 787457.0 322000.0 0.7 0.9159 0.9971 1981221 ChemDiv1_024736 Clc1ccc2N3[C@@H]([C@@H](c4ccc(Br)cc4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E09 compound treatment 715019.0 234000.0 0.48 724977.0 260000.0 0.56 0.7394 0.9972 1981222 ChemDiv1_024737 CCN1CCN(C(=O)NC(C(=O)NC2C3SCC(=C(N3C2=O)C(=O)O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E10 compound treatment 898707.0 418000.0 0.86 866075.0 401000.0 0.87 1.2235 1.0 1981223 ChemDiv1_024738 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccc(F)cc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E11 compound treatment 761540.0 281000.0 0.58 741219.0 276000.0 0.6 0.8322 0.9999 1489196 ChemDiv1_024739 CCOc1ccc(NC(=O)c2c(NC(=O)c3ccncc3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E12 compound treatment 751259.0 271000.0 0.56 740407.0 275000.0 0.6 0.8159 0.9995 1172295 ChemDiv1_024740 CCc1c(C)c(C#N)c2nc3ccccc3n2c1Nc4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E13 compound treatment 701480.0 221000.0 0.46 674467.0 209000.0 0.45 0.6424 1.0 1981224 ChemDiv1_024741 Oc1ccccc1c2cc(Cl)ncn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E14 compound treatment 703387.0 223000.0 0.46 717624.0 252000.0 0.55 0.7112 0.9963 1981225 ChemDiv1_024742 CC(=O)C1=C(C)NC(=C(C#N)[C@@H]1c2ccccc2[N+](=O)[O-])SCc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E15 compound treatment 738847.0 258000.0 0.53 694653.0 229000.0 0.5 0.7278 0.9994 1981226 ChemDiv1_024743 CC1=CCC2(C(C1)c3ccc(F)cc3)C(=O)OC(C)(C)OC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E16 compound treatment 736682.0 256000.0 0.53 716064.0 251000.0 0.54 0.7574 0.9999 1981227 ChemDiv1_024744 NC1=C(C#N)C(C(=c2sc(=Cc3ccccc3C(F)(F)F)c(=O)n12)C#N)c4ccccc4C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E17 compound treatment 733713.0 253000.0 0.52 693382.0 228000.0 0.49 0.7184 0.9996 1981228 ChemDiv1_024745 CCCCN(CCCC)c1ncnc2c1sc3nc(CCC)c4COC(C)(C)Cc4c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E18 compound treatment 748057.0 267000.0 0.55 750863.0 286000.0 0.62 0.8273 0.9984 1189169 ChemDiv1_024746 NC1=C(C#N)C(C(=c2sc(=Cc3ccccc3)c(=O)n12)C#N)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E19 compound treatment 706631.0 226000.0 0.47 709943.0 245000.0 0.53 0.7042 0.998 1981229 ChemDiv1_024747 CC(=O)Nc1ccc(cc1)N2C(=O)CC(NCc3ccc(F)cc3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E20 compound treatment 734076.0 253000.0 0.52 724079.0 259000.0 0.56 0.7659 0.9994 1190526 ChemDiv1_024748 COc1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E21 compound treatment 808617.0 328000.0 0.68 789124.0 324000.0 0.7 0.9742 0.9999 1981230 ChemDiv1_024749 Ic1cccc(c1)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E22 compound treatment 693794.0 213000.0 0.44 664758.0 199000.0 0.43 0.6163 1.0 1310707 ChemDiv1_024750 COc1ccc(cc1)C2Nc3ccc4ccccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E23 mock treatment 700814.0 220000.0 0.45 672428.0 207000.0 0.45 0.6383 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 E24 mock treatment 235644.0 -245000.0 -0.51 239843.0 -225000.0 -0.49 -0.7028 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F01 compound treatment 806973.0 326000.0 0.67 744094.0 279000.0 0.6 0.9029 0.9985 1981231 ChemDiv1_024751 NC1=C(C#N)C2=CCCC[C@H]2[C@H](c3ccccc3Cl)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F02 compound treatment 675425.0 195000.0 0.4 636861.0 172000.0 0.37 0.5468 0.9992 1981232 ChemDiv1_024752 Cc1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F03 compound treatment 719362.0 239000.0 0.49 677668.0 212000.0 0.46 0.6734 0.9994 1981233 ChemDiv1_024753 Ic1ccc(cc1)c2nc3ccccc3nc2c4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F04 compound treatment 687693.0 207000.0 0.43 651888.0 187000.0 0.4 0.5877 0.9996 1544974 ChemDiv1_024754 Cc1ccc(NC(c2nnnn2C(C(Oc3ccc(Cl)cc3)n4cncn4)C(C)(C)C)c5cccc(Cl)c5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F05 compound treatment 750944.0 270000.0 0.56 674897.0 210000.0 0.45 0.7152 0.9947 1150360 ChemDiv1_024755 NC1=C(C#N)C2(CCCC2)Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F06 compound treatment 712174.0 232000.0 0.48 681276.0 216000.0 0.47 0.6684 0.9999 1435658 ChemDiv1_024756 Nc1ccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F07 compound treatment 760441.0 280000.0 0.58 748208.0 283000.0 0.61 0.8413 0.9996 1981234 ChemDiv1_024757 CCc1ccccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6Cl)c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F08 compound treatment 731938.0 251000.0 0.52 687395.0 222000.0 0.48 0.7066 0.9993 1780489 ChemDiv1_024758 Cc1ccc(cc1)N2CCN(C2c3cccc(Cl)c3Cl)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F09 compound treatment 765886.0 285000.0 0.59 702215.0 237000.0 0.51 0.7788 0.9976 1413575 ChemDiv1_024759 CCCC(=O)NC1=C(C(=O)OCC)C2(CCCC2)Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F10 compound treatment 738125.0 257000.0 0.53 698864.0 234000.0 0.51 0.7332 0.9997 1981235 ChemDiv1_024760 Brc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F11 compound treatment 778023.0 297000.0 0.61 741476.0 276000.0 0.6 0.8566 0.9999 1981236 ChemDiv1_024761 Cc1ccc(N=c2oc3ccc4ccccc4c3cc2c5nc6ccccc6s5)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F12 compound treatment 745399.0 265000.0 0.55 700924.0 236000.0 0.51 0.747 0.9994 1981237 ChemDiv1_024762 OC(=O)c1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(Br)cc6)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F13 compound treatment 908043.0 427000.0 0.88 872906.0 408000.0 0.88 1.2476 1.0 1981238 ChemDiv1_024763 COc1cc(cc(OC)c1OC)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F14 compound treatment 712485.0 232000.0 0.48 706637.0 241000.0 0.52 0.7077 0.999 1201818 ChemDiv1_024764 CC1CN(CCC1(OC(=O)C)c2ccccc2)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F15 compound treatment 825791.0 345000.0 0.71 780932.0 316000.0 0.68 0.9868 0.9998 1242292 ChemDiv1_024765 CC(C)(C)C1CC=C2C(C1)C(c3ccc(Cl)cc3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F16 compound treatment 742245.0 262000.0 0.54 706875.0 242000.0 0.52 0.7515 0.9999 1981239 ChemDiv1_024766 Cc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6Cl)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F17 compound treatment 775466.0 295000.0 0.61 728007.0 263000.0 0.57 0.8323 0.9994 1981240 ChemDiv1_024767 [O-][N+](=O)c1cccc(c1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F18 compound treatment 731494.0 251000.0 0.52 665734.0 200000.0 0.43 0.6728 0.9961 1981241 ChemDiv1_024768 CC(C)CN1C[C@H](C)C(CC1C)(OC(=O)C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F19 compound treatment 830301.0 350000.0 0.72 650259.0 185000.0 0.4 0.7934 0.9613 1981242 ChemDiv1_024769 CC(C)(C)c1cc(CCOC(=O)CCc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)cc(c1O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F20 compound treatment 731883.0 251000.0 0.52 668459.0 203000.0 0.44 0.6776 0.9966 1273106 ChemDiv1_024770 CCC1CN(C)CCC1(OC(=O)C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F21 compound treatment 740236.0 260000.0 0.54 663897.0 199000.0 0.43 0.6828 0.994 1113524 ChemDiv1_024771 [O-][N+](=O)c1ccc2-c3ccccc3S(=O)(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F22 compound treatment 715379.0 235000.0 0.48 677968.0 213000.0 0.46 0.668 0.9997 1981243 ChemDiv1_024772 CCC1C/C(=C\c2ccc(OC)cc2)/C(=O)\C(=C\c3ccc(OC)cc3)\C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F23 mock treatment 707149.0 226000.0 0.47 755127.0 290000.0 0.63 0.7741 0.9895 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 F24 mock treatment 238104.0 -243000.0 -0.5 217507.0 -248000.0 -0.54 -0.7334 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G01 compound treatment 627422.0 147000.0 0.3 599428.0 134000.0 0.29 0.4194 0.9998 1981244 ChemDiv1_024773 CCOc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G02 compound treatment 832378.0 352000.0 0.73 827298.0 362000.0 0.78 1.0673 0.9993 1981245 ChemDiv1_024774 Clc1ccc(cc1Cl)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G03 compound treatment 696428.0 216000.0 0.45 664313.0 199000.0 0.43 0.6195 0.9999 1317913 ChemDiv1_024775 COc1ccc(cc1)N2C(=O)c3ccc(Oc4ccccc4OC)cc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G04 compound treatment 778042.0 297000.0 0.61 780920.0 316000.0 0.68 0.917 0.9986 1981246 ChemDiv1_024776 Fc1cccc(c1)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G05 compound treatment 743578.0 263000.0 0.54 728100.0 263000.0 0.57 0.7859 0.9997 1981247 ChemDiv1_024777 Cc1nn(c2ccc(Cl)cc2)c3oc(=O)cc(C)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G06 compound treatment 773037.0 292000.0 0.6 812977.0 348000.0 0.75 0.9588 0.994 1981248 ChemDiv1_024778 CCOc1ccc(cc1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G07 compound treatment 724601.0 244000.0 0.5 697924.0 233000.0 0.5 0.712 1.0 1925063 ChemDiv1_024779 COc1ccc(cc1)C(=O)N/C(=C/c2cccs2)/C(=O)NCCN3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G08 compound treatment 934049.0 453000.0 0.94 947799.0 482000.0 1.04 1.4002 0.9985 1981249 ChemDiv1_024780 CC(=O)[C@@H]1[C@@H](c2ccc3OCOc3c2)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G09 compound treatment 745843.0 265000.0 0.55 687939.0 223000.0 0.48 0.7277 0.998 1340656 ChemDiv1_024781 COc1cc(ccc1O)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G10 compound treatment 693969.0 213000.0 0.44 697688.0 232000.0 0.5 0.6669 0.9978 1443175 ChemDiv1_024782 COc1cc(cc(OC)c1OC)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G11 compound treatment 745998.0 265000.0 0.55 729118.0 264000.0 0.57 0.791 0.9998 1588233 ChemDiv1_024783 COc1ccc(NC(=O)c2c(NC(=O)c3ccncc3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G12 compound treatment 710706.0 230000.0 0.47 666912.0 202000.0 0.44 0.6443 0.9991 1981250 ChemDiv1_024784 [O-][N+](=O)c1cccc(c1)c2nc(c([nH]2)c3ccc(cc3)c4nc([nH]c4c5ccccc5)c6cccc(c6)[N+](=O)[O-])c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G13 compound treatment 726265.0 246000.0 0.51 682408.0 217000.0 0.47 0.6907 0.9993 1981251 ChemDiv1_024785 COc1cc(ncn1)c2ccccc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G14 compound treatment 719990.0 239000.0 0.49 689590.0 224000.0 0.49 0.6925 1.0 1625308 ChemDiv1_024786 Nn1cnc2-c3ccccc3CC4(CCCCC4)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G15 compound treatment 716538.0 236000.0 0.49 691458.0 226000.0 0.49 0.6904 1.0 1981252 ChemDiv1_024787 CC1=CCC2(C(C1)c3ccc(Cl)cc3)C(=O)OC(C)(C)OC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G16 compound treatment 699502.0 219000.0 0.45 690864.0 226000.0 0.49 0.6646 0.9993 1981253 ChemDiv1_024788 NC1=C(C#N)C(C(=c2sc(=Cc3ccc(cc3)[N+](=O)[O-])c(=O)n12)C#N)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G17 compound treatment 748934.0 268000.0 0.55 721292.0 256000.0 0.55 0.7833 1.0 1138339 ChemDiv1_024789 CCCCc1nc2sc3c(ncnc3c2c4CC(C)(C)OCc14)N5CCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G18 compound treatment 879108.0 398000.0 0.82 848666.0 383000.0 0.83 1.1683 1.0 1981254 ChemDiv1_024790 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccsc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G19 compound treatment 742554.0 262000.0 0.54 733195.0 268000.0 0.58 0.7922 0.9994 1981255 ChemDiv1_024791 OC(=O)c1ccc2nc(c3cccs3)c(nc2c1)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G20 compound treatment 714738.0 234000.0 0.48 683495.0 218000.0 0.47 0.6755 0.9999 1981256 ChemDiv1_024792 CCCOc1ccc(cc1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G21 compound treatment 904944.0 424000.0 0.88 818235.0 353000.0 0.76 1.1594 0.9977 1981257 ChemDiv1_024793 NC1=C(C#N)C2=CCCCC2C(c3ccc(Cl)c(Cl)c3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G22 compound treatment 683195.0 203000.0 0.42 656232.0 191000.0 0.41 0.5878 1.0 1981258 ChemDiv1_024794 Brc1ccc2nc3c(Nc4ccccc4)ccc5C(=O)c6ccccc6-c(c2c1)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G23 mock treatment 752460.0 272000.0 0.56 660291.0 195000.0 0.42 0.6951 0.9901 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 G24 mock treatment 251393.0 -229000.0 -0.47 279237.0 -186000.0 -0.4 -0.6195 -0.9968 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H01 compound treatment 643160.0 162000.0 0.34 580331.0 115000.0 0.25 0.4132 0.9892 1981259 ChemDiv1_024795 O=C1C2C(C3C(=O)CC2c4ccccc34)C(=O)N1c5ccc(N=Nc6ccccc6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H02 compound treatment 1030681.0 550000.0 1.14 615957.0 151000.0 0.33 1.0333 0.8748 1981260 ChemDiv1_024796 Clc1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H03 compound treatment 688140.0 207000.0 0.43 685998.0 221000.0 0.48 0.6405 0.9985 1718616 ChemDiv1_024797 Nc1ccccc1n2c(c3C(=O)c4ccccc4C(=O)c3c2c5ccc(Cl)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H04 compound treatment 691651.0 211000.0 0.44 645612.0 180000.0 0.39 0.5839 0.9985 1981261 ChemDiv1_024798 CSC1=N/C(=N\c2cccc(c2)C(F)(F)F)/C3(CCCCC3)N1c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H05 compound treatment 710962.0 230000.0 0.48 662230.0 197000.0 0.43 0.6375 0.9985 1981262 ChemDiv1_024799 ClCC(=O)NC1=C(C#N)C2(CCCCC2)Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H06 compound treatment 794034.0 313000.0 0.65 825967.0 361000.0 0.78 1.0093 0.9956 1129679 ChemDiv1_024800 Cc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H07 compound treatment 742429.0 262000.0 0.54 686295.0 221000.0 0.48 0.7202 0.9981 1981263 ChemDiv1_024801 CN(C)c1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H08 compound treatment 732955.0 252000.0 0.52 674151.0 209000.0 0.45 0.6878 0.9975 1981264 ChemDiv1_024802 O=C1C2C(C(=O)N1c3ccccc3)C4(/C=N/c5cccc6ccccc56)c7ccccc7C2c8ccccc84 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H09 compound treatment 740219.0 260000.0 0.54 675516.0 210000.0 0.45 0.7005 0.9967 1469968 ChemDiv1_024803 CCOC(=O)C1=C(NC(=O)CC)c2ccccc2CC31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H10 compound treatment 743475.0 263000.0 0.54 715130.0 250000.0 0.54 0.7659 1.0 1981265 ChemDiv1_024804 COC(=O)c1ccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(C)cc6)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H11 compound treatment 798765.0 318000.0 0.66 807453.0 342000.0 0.74 0.9879 0.9982 1981266 ChemDiv1_024805 [O-][N+](=O)c1ccccc1N=c2oc3ccc4ccccc4c3cc2c5nc6ccccc6s5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H12 compound treatment 696966.0 216000.0 0.45 694929.0 230000.0 0.5 0.6671 0.9986 1981267 ChemDiv1_024806 OC(=O)c1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6cccc7ccccc67)c8ccccc48)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H13 compound treatment 801072.0 320000.0 0.66 743681.0 278000.0 0.6 0.8937 0.9989 1981268 ChemDiv1_024807 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H14 compound treatment 718764.0 238000.0 0.49 687453.0 222000.0 0.48 0.6875 0.9999 1912811 ChemDiv1_024808 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3cccc(c3)[N+](=O)[O-])C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H15 compound treatment 755205.0 275000.0 0.57 717774.0 252000.0 0.55 0.7871 0.9998 1981269 ChemDiv1_024809 COc1ccc(cc1)S(=O)(=O)Oc2ccc(/C=N/NC(=O)C3(CCC3)C(=O)N\N=C\c4ccc(OS(=O)(=O)c5ccc(OC)cc5)cc4)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H16 compound treatment 707196.0 227000.0 0.47 683684.0 218000.0 0.47 0.6648 1.0 1981270 ChemDiv1_024810 Cc1cc(c2ccc(/C=N/c3c(nc4ccccn34)c5ccco5)o2)c(C)cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H17 compound treatment 751423.0 271000.0 0.56 712979.0 248000.0 0.54 0.7742 0.9998 1981271 ChemDiv1_024811 Cc1ccc(cc1)c2nn(cc2/C=N/NC(=O)c3ccc(Br)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H18 compound treatment 744042.0 263000.0 0.54 672161.0 207000.0 0.45 0.701 0.9953 1381582 ChemDiv1_024812 CC(=O)N1c2ccc(NC(=O)c3ccccc3)cc2C(C)(CC1(C)C)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H19 compound treatment 720399.0 240000.0 0.49 686773.0 221000.0 0.48 0.6888 0.9999 1202249 ChemDiv1_024813 CCN(CC)c1ccc(cc1)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H20 compound treatment 825733.0 345000.0 0.71 734456.0 269000.0 0.58 0.9155 0.995 1981272 ChemDiv1_024814 CC(=O)[C@@H]1[C@@H](c2ccc(F)cc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H21 compound treatment 737967.0 257000.0 0.53 661078.0 196000.0 0.42 0.6751 0.9937 1171543 ChemDiv1_024815 Cc1cccc(c1)N2CCN(C2c3ccc(Cl)cc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H22 compound treatment 705438.0 225000.0 0.46 652311.0 187000.0 0.4 0.6142 0.9977 1981273 ChemDiv1_024816 Cc1cccc(C)c1n2nnnc2C3(CCCC3)Nc4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H23 mock treatment 712217.0 232000.0 0.48 655897.0 191000.0 0.41 0.6296 0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 H24 mock treatment 203883.0 -277000.0 -0.57 216020.0 -249000.0 -0.54 -0.7856 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I01 compound treatment 635021.0 154000.0 0.32 581538.0 116000.0 0.25 0.4031 0.9931 1981274 ChemDiv1_024817 CCOc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccccc5OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I02 compound treatment 697888.0 217000.0 0.45 720479.0 255000.0 0.55 0.7075 0.9947 1981275 ChemDiv1_024818 Clc1ccc(cc1Cl)[C@H]2[C@@H](N3C=Cc4ccccc4C3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I03 compound treatment 686129.0 205000.0 0.42 662403.0 197000.0 0.43 0.6015 1.0 1213571 ChemDiv1_024819 COc1ccccc1Oc2ccc3C(=O)N(C(=O)c3c2)c4ccccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I04 compound treatment 717118.0 236000.0 0.49 699441.0 234000.0 0.51 0.7034 0.9998 1981276 ChemDiv1_024820 COc1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I05 compound treatment 679343.0 199000.0 0.41 650740.0 185000.0 0.4 0.5737 0.9999 1660749 ChemDiv1_024821 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I06 compound treatment 832867.0 352000.0 0.73 726539.0 261000.0 0.57 0.9138 0.9923 1981277 ChemDiv1_024822 CC(=O)[C@@H]1[C@@H](c2ccccc2F)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I07 compound treatment 727963.0 247000.0 0.51 723830.0 258000.0 0.56 0.7566 0.999 1924536 ChemDiv1_024823 O=C(NCCCN1CCOCC1)/C(=C/c2cccs2)/NC(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I08 compound treatment 886025.0 405000.0 0.84 843112.0 378000.0 0.82 1.1698 0.9999 1981278 ChemDiv1_024824 CC(=O)Oc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I09 compound treatment 732377.0 252000.0 0.52 697793.0 232000.0 0.5 0.7232 0.9999 1554336 ChemDiv1_024825 Brc1ccc(cc1)C(=O)COC(=O)c2ccc(NC(=O)c3ccccc3Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I10 compound treatment 699107.0 218000.0 0.45 674679.0 209000.0 0.45 0.6392 1.0 1981279 ChemDiv1_024826 COc1ccc(OC)c(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I11 compound treatment 734696.0 254000.0 0.52 696776.0 231000.0 0.5 0.725 0.9997 1340831 ChemDiv1_024827 COc1ccccc1NC(=O)c2c(NC(=O)c3ccc(C)cc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I12 compound treatment 688473.0 208000.0 0.43 675699.0 210000.0 0.46 0.6253 0.9996 1775082 ChemDiv1_024828 OCC1OC(C(O)C1O)n2c(nc3c(=O)[nH]cnc23)N4CCNCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I13 compound treatment 710853.0 230000.0 0.48 709792.0 244000.0 0.53 0.7101 0.9986 1463610 ChemDiv1_024829 CCOc1cc(ncn1)c2ccccc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I14 compound treatment 731505.0 251000.0 0.52 694674.0 229000.0 0.5 0.7171 0.9998 1981280 ChemDiv1_024830 Clc1ccc(N=c2oc3ccccc3cc2c4nc5ccccc5s4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I15 compound treatment 730282.0 250000.0 0.52 734976.0 270000.0 0.58 0.777 0.9981 1675478 ChemDiv1_024831 CC1=CCC(C(C1)c2ccc(F)cc2)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I16 compound treatment 714823.0 234000.0 0.48 676642.0 211000.0 0.46 0.6652 0.9996 1981281 ChemDiv1_024832 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I17 compound treatment 738887.0 258000.0 0.53 726970.0 262000.0 0.57 0.7773 0.9995 1369567 ChemDiv1_024833 CCCc1nc2sc3c(NCCC(C)C)ncnc3c2c4CC(C)(C)OCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I18 compound treatment 695104.0 214000.0 0.44 667447.0 202000.0 0.44 0.6223 1.0 1713628 ChemDiv1_024834 Ic1ccccc1c2c3c(=O)c4ccccc4c3nc5c6ccccc6c(=O)c25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I19 compound treatment 862923.0 382000.0 0.79 967806.0 502000.0 1.09 1.327 0.9876 1981282 ChemDiv1_024835 CCCCOc1ccc2N/C(=C(/C(=C(Cl)Cl)Cl)\[N+](=O)[O-])/c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I20 compound treatment 700792.0 220000.0 0.45 683311.0 218000.0 0.47 0.6549 0.9998 1365206 ChemDiv1_024836 CC(=O)Oc1ccc2oc3CCCC(=O)c3c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I21 compound treatment 749073.0 268000.0 0.55 729107.0 264000.0 0.57 0.7955 0.9999 1645903 ChemDiv1_024837 COc1ccc(OC)c(c1)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I22 compound treatment 721805.0 241000.0 0.5 729587.0 264000.0 0.57 0.7564 0.9976 1981283 ChemDiv1_024838 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I23 mock treatment 715130.0 234000.0 0.48 658781.0 193000.0 0.42 0.6383 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 I24 mock treatment 201223.0 -279000.0 -0.58 219737.0 -246000.0 -0.53 -0.7838 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J01 compound treatment 651492.0 171000.0 0.35 607087.0 142000.0 0.31 0.4663 0.9976 1981284 ChemDiv1_024839 COc1cccc(C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J02 compound treatment 651575.0 171000.0 0.35 641045.0 176000.0 0.38 0.5184 0.9993 1513905 ChemDiv1_024840 Sc1nnc2c(Nc3ccc(Cl)cc3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J03 compound treatment 711046.0 230000.0 0.48 645362.0 180000.0 0.39 0.6118 0.9951 1981285 ChemDiv1_024841 Cc1ccc2N(C(=O)c3ccccc3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J04 compound treatment 671473.0 191000.0 0.39 670032.0 205000.0 0.44 0.5918 0.9983 1733167 ChemDiv1_024842 CN1CCN(CC1)c2c(F)c(N)c3c(=O)c(cn(c4ccc(F)c(F)c4)c3c2F)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J05 compound treatment 840615.0 360000.0 0.74 771813.0 306000.0 0.66 0.9944 0.9984 1981286 ChemDiv1_024843 NC1=C(C#N)C2=CCCC[C@H]2[C@H](c3cccnc3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J06 compound treatment 681127.0 200000.0 0.41 657977.0 193000.0 0.42 0.5874 1.0 1981287 ChemDiv1_024844 CCC(C)N1C(=O)N(C(n2oc(=O)n(c3ccc(Cl)c(Cl)c3)c2=O)C1(C)C)c4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J07 compound treatment 745111.0 264000.0 0.55 723206.0 258000.0 0.56 0.7806 0.9999 1981288 ChemDiv1_024845 Fc1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J08 compound treatment 727919.0 247000.0 0.51 710769.0 245000.0 0.53 0.7365 0.9998 1981289 ChemDiv1_024846 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Br)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J09 compound treatment 789907.0 309000.0 0.64 726352.0 261000.0 0.56 0.8508 0.9981 1981290 ChemDiv1_024847 O=C(NC1=C(C#N)C2(CCCCC2)Cc3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J10 compound treatment 736794.0 256000.0 0.53 679984.0 215000.0 0.46 0.7024 0.9979 1981291 ChemDiv1_024848 Oc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J11 compound treatment 745744.0 265000.0 0.55 716665.0 251000.0 0.54 0.7716 1.0 1981292 ChemDiv1_024849 O(c1ccc(N=c2oc3ccc4ccccc4c3cc2c5nc6ccccc6s5)cc1)c7ccc(N=c8oc9ccc%10ccccc%10c9cc8c%11nc%12ccccc%12s%11)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J12 compound treatment 720872.0 240000.0 0.5 677554.0 212000.0 0.46 0.6754 0.9993 1981293 ChemDiv1_024850 OC(=O)c1ccccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6cccc7ccccc67)c8ccccc48 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J13 compound treatment 708255.0 228000.0 0.47 675033.0 210000.0 0.45 0.6531 0.9999 1981294 ChemDiv1_024851 [O-][N+](=O)c1ccc(NN=C2c3cc(cc([N+](=O)[O-])c3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J14 compound treatment 748370.0 268000.0 0.55 687796.0 222000.0 0.48 0.7312 0.9976 1981295 ChemDiv1_024852 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4cc(Br)c(O)c(O)c4Br)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J15 compound treatment 1065102.0 584000.0 1.21 1121194.0 656000.0 1.42 1.8568 0.9967 1981296 ChemDiv1_024853 NC1=C(C#N)C2=CCN(Cc3ccccc3)CC2C(c4ccc(Br)cc4)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J16 compound treatment 785623.0 305000.0 0.63 740616.0 275000.0 0.6 0.8664 0.9996 1582165 ChemDiv1_024854 O=C([C@@H]1[C@@H](c2ccccc2)C(C#N)(C#N)[C@H]3C=Cc4c(ccc5ccccc45)N13)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J17 compound treatment 755180.0 275000.0 0.57 703259.0 238000.0 0.51 0.7648 0.9989 1981297 ChemDiv1_024855 Brc1cccc(c1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J18 compound treatment 746309.0 266000.0 0.55 700609.0 235000.0 0.51 0.7478 0.9993 1981298 ChemDiv1_024856 CCc1ccc(cc1)c2c3C(=O)c4ccccc4C(=O)c3c(c5ccccc5)n2c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J19 compound treatment 755535.0 275000.0 0.57 681670.0 216000.0 0.47 0.7323 0.9954 1643953 ChemDiv1_024857 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(O)cc3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J20 compound treatment 699087.0 218000.0 0.45 688056.0 223000.0 0.48 0.6597 0.9994 1561479 ChemDiv1_024858 Cc1ccc(NC(=O)C2CC2(c3cccc(C)c3)c4cccc(C)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J21 compound treatment 739873.0 259000.0 0.54 683185.0 218000.0 0.47 0.7118 0.998 1193101 ChemDiv1_024859 COc1ccc(Br)cc1C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J22 compound treatment 703900.0 223000.0 0.46 676974.0 212000.0 0.46 0.6497 1.0 1981299 ChemDiv1_024860 [O-][N+](=O)c1ccc(Cl)c(c1)c2ccc(/C=N/c3c(nc4ccccn34)c5ccco5)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J23 mock treatment 718666.0 238000.0 0.49 669995.0 205000.0 0.44 0.6606 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 J24 mock treatment 229612.0 -251000.0 -0.52 249121.0 -216000.0 -0.47 -0.6974 -0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K01 compound treatment 628606.0 148000.0 0.31 580635.0 115000.0 0.25 0.3924 0.995 1981300 ChemDiv1_024861 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccccc5CC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K02 compound treatment 692818.0 212000.0 0.44 678980.0 214000.0 0.46 0.6366 0.9996 1981301 ChemDiv1_024862 Fc1ccc(cc1)[C@H]2[C@@H](N3C=Cc4ccccc4C3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K03 compound treatment 658152.0 177000.0 0.37 638661.0 173000.0 0.38 0.5243 0.9999 1417464 ChemDiv1_024863 COc1ccccc1Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K04 compound treatment 717240.0 237000.0 0.49 677421.0 212000.0 0.46 0.6699 0.9995 1981302 ChemDiv1_024864 Clc1ccc2N3[C@@H]([C@@H](c4cccnc4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K05 compound treatment 699350.0 219000.0 0.45 663322.0 198000.0 0.43 0.6222 0.9997 1577151 ChemDiv1_024865 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(F)cc2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K06 compound treatment 783779.0 303000.0 0.63 796365.0 331000.0 0.72 0.9491 0.9977 1981303 ChemDiv1_024866 CCOc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K07 compound treatment 694998.0 214000.0 0.44 676253.0 211000.0 0.46 0.6356 0.9999 1388280 ChemDiv1_024867 O=C(COc1ccccc1)Nc2cccc3c(NC(=O)COc4ccccc4)cccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K08 compound treatment 796806.0 316000.0 0.65 735525.0 270000.0 0.58 0.875 0.9985 1981304 ChemDiv1_024868 CCOc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K09 compound treatment 728353.0 248000.0 0.51 685374.0 220000.0 0.48 0.6983 0.9994 1981305 ChemDiv1_024869 FC(F)(F)c1ccc(Cl)c(c1)N2C(=O)C3C4CCC(C4)C3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K10 compound treatment 724701.0 244000.0 0.5 651250.0 186000.0 0.4 0.6407 0.9938 1981306 ChemDiv1_024870 [O-][N+](=O)c1cccc(c1)c2nc(c([nH]2)c3ccc(Br)cc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K11 compound treatment 728144.0 247000.0 0.51 679674.0 214000.0 0.46 0.6893 0.9988 1458981 ChemDiv1_024871 COc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3F)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K12 compound treatment 664185.0 184000.0 0.38 632877.0 168000.0 0.36 0.5243 0.9998 1981307 ChemDiv1_024872 [O-][N+](=O)c1ccc(cc1)c2nc([nH]c2c3ccc(Oc4ccc(cc4)c5nc([nH]c5c6ccc(cc6)[N+](=O)[O-])c7ccccc7)cc3)c8ccccc8 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K13 compound treatment 683152.0 202000.0 0.42 682760.0 217000.0 0.47 0.6283 0.9983 1981308 ChemDiv1_024873 COc1ccc(O)c(c1)c2ccncn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K14 compound treatment 727853.0 247000.0 0.51 647310.0 182000.0 0.39 0.6393 0.9918 1981309 ChemDiv1_024874 Clc1ccccc1/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K15 compound treatment 731250.0 251000.0 0.52 690790.0 225000.0 0.49 0.7108 0.9996 1981310 ChemDiv1_024875 CC1=CCC(C(C1)c2ccc(Br)cc2)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K16 compound treatment 703182.0 223000.0 0.46 664153.0 199000.0 0.43 0.6291 0.9995 1981311 ChemDiv1_024876 COc1ccc(cc1)[C@H]2[C@@H](SC(=C2C#N)N)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K17 compound treatment 721929.0 241000.0 0.5 715008.0 250000.0 0.54 0.7343 0.9992 1981312 ChemDiv1_024877 CCCCCNc1ncnc2c1sc3nc(CCC)c4COC(C)(C)Cc4c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K18 compound treatment 705567.0 225000.0 0.46 695740.0 230000.0 0.5 0.6809 0.9994 1981313 ChemDiv1_024878 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(OCC=C)cc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K19 compound treatment 716808.0 236000.0 0.49 714272.0 249000.0 0.54 0.7257 0.9988 1161475 ChemDiv1_024879 Cc1ccc2nc3c(C#N)c(C)cc(N4CCCCC4)n3c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K20 compound treatment 708811.0 228000.0 0.47 653468.0 188000.0 0.41 0.6209 0.9974 1981314 ChemDiv1_024880 C1CCC2(C1)Cc3ccccc3-c4nc(nc(N5CCCCC5)c42)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K21 compound treatment 808278.0 328000.0 0.68 746963.0 282000.0 0.61 0.9092 0.9987 1720017 ChemDiv1_024881 Clc1ccc(cc1Cl)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K22 compound treatment 691408.0 211000.0 0.44 649004.0 184000.0 0.4 0.5887 0.999 1293598 ChemDiv1_024882 CCN(CC)c1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K23 mock treatment 712911.0 232000.0 0.48 647862.0 183000.0 0.4 0.6183 0.9954 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 K24 mock treatment 216313.0 -264000.0 -0.55 226701.0 -239000.0 -0.52 -0.7511 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L01 compound treatment 650683.0 170000.0 0.35 613661.0 148000.0 0.32 0.4752 0.999 1981315 ChemDiv1_024883 CC(=O)Oc1ccc2ccccc2c1/C=N/c3oc(c(c3C#N)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L02 compound treatment 680062.0 199000.0 0.41 637724.0 172000.0 0.37 0.5549 0.9988 1981316 ChemDiv1_024884 CSC1=N/C(=N\c2cccc(c2)C(F)(F)F)/C3(CCCCC3)N1c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L03 compound treatment 712679.0 232000.0 0.48 664290.0 199000.0 0.43 0.6431 0.9986 1503035 ChemDiv1_024885 Cn1c(CC(=O)Nc2ccc(Cl)cc2)c(Sc3ccccc3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L04 compound treatment 674547.0 194000.0 0.4 664633.0 199000.0 0.43 0.588 0.9993 1981317 ChemDiv1_024886 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccc(Br)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L05 compound treatment 719287.0 239000.0 0.49 689497.0 224000.0 0.49 0.6914 1.0 1186265 ChemDiv1_024887 Cc1ccc(cc1)C2(CC2C(=O)Nc3cccc(C)c3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L06 compound treatment 694759.0 214000.0 0.44 691750.0 226000.0 0.49 0.659 0.9987 1981318 ChemDiv1_024888 CN1C2CCC1[C@H]3[C@H](c4ccc(F)cc4)C(C#N)(C#N)C(=C(C#N)C3=C2)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L07 compound treatment 728650.0 248000.0 0.51 708249.0 243000.0 0.53 0.7337 0.9999 1981319 ChemDiv1_024889 Fc1cccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L08 compound treatment 724184.0 244000.0 0.5 681011.0 216000.0 0.47 0.6855 0.9993 1512271 ChemDiv1_024890 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L09 compound treatment 729267.0 249000.0 0.51 717282.0 252000.0 0.55 0.7485 0.9995 1981320 ChemDiv1_024891 O=C(Cc1ccccc1)NC2=C(C#N)C3(CCCCC3)Cc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L10 compound treatment 732577.0 252000.0 0.52 667009.0 202000.0 0.44 0.6763 0.9962 1981321 ChemDiv1_024892 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5ccc(O)cc5)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L11 compound treatment 793876.0 313000.0 0.65 782248.0 317000.0 0.69 0.9422 0.9996 1981322 ChemDiv1_024893 COc1cc(cc(OC)c1OC)[C@@H]2[C@H](N3[C@H](C=Cc4cc(Cl)ccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L12 compound treatment 723900.0 243000.0 0.5 678584.0 213000.0 0.46 0.6814 0.9991 1254906 ChemDiv1_024894 O=C(Nc1ccc2OCOc2c1)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L13 compound treatment 770341.0 290000.0 0.6 741813.0 276000.0 0.6 0.846 1.0 1720112 ChemDiv1_024895 CC(C)c1ccc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccc(cc4)C(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L14 compound treatment 724961.0 244000.0 0.5 688267.0 223000.0 0.48 0.6978 0.9998 1981323 ChemDiv1_024896 CC(CC=C(c1ccccc1)c2ccccc2)C3CCC4C5CC=C6CCCC(O)C6(C)C5CCC34C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L15 compound treatment 777565.0 297000.0 0.61 727606.0 262000.0 0.57 0.8348 0.9993 1981324 ChemDiv1_024897 COc1cc(cc(OC)c1OC)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L16 compound treatment 710434.0 230000.0 0.47 634296.0 169000.0 0.37 0.594 0.9917 1981325 ChemDiv1_024898 CC1=NN(C(=O)C21C(c3ccccc3Cl)C42C(=NN(C4=O)c5ccc(Cl)cc5C)C)c6ccc(C)cc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L17 compound treatment 756186.0 276000.0 0.57 734769.0 269000.0 0.58 0.8145 0.9999 1981326 ChemDiv1_024899 Cc1ccc(cc1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L18 compound treatment 708494.0 228000.0 0.47 690711.0 225000.0 0.49 0.6775 0.9998 1920159 ChemDiv1_024900 COc1ccc(cc1)c2c3C(=O)c4ccccc4C(=O)c3c(c5ccccc5)n2c6ccc(OC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L19 compound treatment 758148.0 277000.0 0.57 711345.0 246000.0 0.53 0.7815 0.9993 1329063 ChemDiv1_024901 COc1ccc(C2C3CCC=C3C(=C(N)C2(C#N)C#N)C#N)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L20 compound treatment 727152.0 246000.0 0.51 689506.0 224000.0 0.49 0.7029 0.9997 1607971 ChemDiv1_024902 Cc1cccc(c1)C2(CC2C(=O)Nc3ccc(C)cc3C)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L21 compound treatment 878389.0 398000.0 0.82 778349.0 313000.0 0.68 1.0596 0.9954 1981327 ChemDiv1_024903 CCCCOc1ccc(cc1)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L22 compound treatment 691849.0 211000.0 0.44 675609.0 210000.0 0.46 0.6301 0.9998 1981328 ChemDiv1_024904 CCC1C/C(=C\c2ccc(Br)cc2)/C(=O)\C(=C\c3ccc(Br)cc3)\C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L23 mock treatment 750379.0 270000.0 0.56 683195.0 218000.0 0.47 0.7271 0.9966 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 L24 mock treatment 231465.0 -249000.0 -0.51 243298.0 -222000.0 -0.48 -0.7036 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M01 compound treatment 647492.0 167000.0 0.34 578463.0 113000.0 0.24 0.4166 0.986 1981329 ChemDiv1_024905 Cc1ccccc1OCCOc2ccc(/C=C\3/C(=N)N4C(=CSC4=NC3=O)c5ccccc5)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M02 compound treatment 793948.0 313000.0 0.65 760352.0 295000.0 0.64 0.9088 1.0 1303536 ChemDiv1_024906 O=C(C1C(c2cccnc2)C(C#N)(C#N)C3C=Cc4cccnc4N13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M03 compound treatment 746546.0 266000.0 0.55 693889.0 229000.0 0.49 0.7379 0.9987 1981330 ChemDiv1_024907 CN1/C(=C/c2sc3ccccc3[n+]2CCCS(=O)(=O)O)/Sc4cc(C)ccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M04 compound treatment 963008.0 482000.0 1.0 914591.0 449000.0 0.97 1.3916 0.9999 1981331 ChemDiv1_024908 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2cccc3cc(Cl)ccc23)c4cccnc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M05 compound treatment 687835.0 207000.0 0.43 657609.0 192000.0 0.42 0.5966 0.9999 1477221 ChemDiv1_024909 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(F)cc2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M06 compound treatment 701133.0 220000.0 0.46 692390.0 227000.0 0.49 0.6693 0.9993 1981332 ChemDiv1_024910 Clc1ccc2N3[C@@H]([C@@H](c4cccc(I)c4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M07 compound treatment 710429.0 230000.0 0.47 693865.0 229000.0 0.49 0.6851 0.9998 1487397 ChemDiv1_024911 O=C(COc1ccccc1)Nc2ccccc2NC(=O)COc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M08 compound treatment 880392.0 400000.0 0.83 870418.0 405000.0 0.88 1.2034 0.9995 1981333 ChemDiv1_024912 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3F)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M09 compound treatment 711046.0 230000.0 0.48 679152.0 214000.0 0.46 0.6635 0.9999 1737221 ChemDiv1_024913 COc1ccc(NC(=O)c2c(NC(=O)c3ccccc3F)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M10 compound treatment 695835.0 215000.0 0.44 635411.0 170000.0 0.37 0.5744 0.9956 1279268 ChemDiv1_024914 ON1C(N(CC1=O)C(=O)c2ccccc2)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M11 compound treatment 677902.0 197000.0 0.41 672680.0 207000.0 0.45 0.6052 0.9988 1377389 ChemDiv1_024915 COc1ccccc1NC(=O)c2c(NC(=O)c3cccc(Br)c3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M12 compound treatment 657824.0 177000.0 0.37 632570.0 167000.0 0.36 0.5145 1.0 1981334 ChemDiv1_024916 Ic1cccc(c1)c2nc([nH]c2c3ccc(cc3)c4nc([nH]c4c5cccc(I)c5)c6ccccc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M13 compound treatment 732132.0 251000.0 0.52 659447.0 194000.0 0.42 0.6641 0.9945 1981335 ChemDiv1_024917 Oc1ccc(Br)cc1c2ccncn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M14 compound treatment 711965.0 231000.0 0.48 673277.0 208000.0 0.45 0.6559 0.9996 1164471 ChemDiv1_024918 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3cccc(Cl)c3Cl)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M15 compound treatment 717347.0 237000.0 0.49 668849.0 204000.0 0.44 0.6569 0.9987 1981336 ChemDiv1_024919 Cc1cc(=O)oc2n(nc(c12)C(F)(F)F)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M16 compound treatment 681550.0 201000.0 0.41 631494.0 166000.0 0.36 0.5475 0.9975 1981337 ChemDiv1_024920 COc1ccc(cc1)[C@H]2[C@@H](SC(=C2C#N)N)C(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M17 compound treatment 728898.0 248000.0 0.51 678526.0 213000.0 0.46 0.6886 0.9986 1202752 ChemDiv1_024921 CCCc1nc2sc3c(NCCO)ncnc3c2c4CC(C)(C)OCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M18 compound treatment 695820.0 215000.0 0.44 655212.0 190000.0 0.41 0.6046 0.9992 1776404 ChemDiv1_024922 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5ccc(Cl)c(c5)C(=O)O)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M19 compound treatment 659587.0 179000.0 0.37 611263.0 146000.0 0.32 0.4845 0.997 1981338 ChemDiv1_024923 [O-][N+](=O)c1cc(cc2C(=C(C#N)C#N)c3cc(cc([N+](=O)[O-])c3-c21)S(=O)(=O)NCc4ccccc4)S(=O)(=O)NCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M20 compound treatment 863332.0 383000.0 0.79 814143.0 349000.0 0.75 1.0924 0.9997 1981339 ChemDiv1_024924 CCCN1CC=C2C(C1)C(c3ccc(OC)cc3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M21 compound treatment 744398.0 264000.0 0.54 683510.0 218000.0 0.47 0.7189 0.9975 1981340 ChemDiv1_024925 COc1ccc(OC)c(c1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M22 compound treatment 692073.0 211000.0 0.44 639796.0 174000.0 0.38 0.5756 0.9974 1981341 ChemDiv1_024926 CC1(C)OCC(O1)[C@H]2O[C@@H]3OC(C)(C)OC3C2OC(=O)Nc4ccc(Cc5ccc(NC(=O)OC6[C@H](O[C@@H]7OC(C)(C)OC67)C8COC(C)(C)O8)cc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M23 mock treatment 719401.0 239000.0 0.49 666626.0 201000.0 0.44 0.6565 0.9981 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 M24 mock treatment 222418.0 -258000.0 -0.53 362602.0 -103000.0 -0.22 -0.5342 -0.9248 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N01 compound treatment 858105.0 377000.0 0.78 716846.0 252000.0 0.54 0.9358 0.9846 1350502 ChemDiv1_024927 COc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N02 compound treatment 694539.0 214000.0 0.44 636131.0 171000.0 0.37 0.5736 0.9961 1742343 ChemDiv1_024928 CC(C)(C)C(C(Oc1ccc(Cl)cc1)n2cncn2)n3nnnc3C(N4CCCCC4)c5ccccc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N03 compound treatment 698267.0 218000.0 0.45 689059.0 224000.0 0.48 0.66 0.9993 1778402 ChemDiv1_024929 CC(C)c1ccc(cc1)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N04 compound treatment 687806.0 207000.0 0.43 642933.0 178000.0 0.38 0.5741 0.9986 1981342 ChemDiv1_024930 Cc1c(/N=C/c2c(F)cccc2Cl)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N05 compound treatment 700726.0 220000.0 0.45 691834.0 226000.0 0.49 0.6678 0.9993 1264782 ChemDiv1_024931 Cc1cccc(NC(=O)C2CC2(c3ccccc3)c4ccccc4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N06 compound treatment 675960.0 195000.0 0.4 666695.0 201000.0 0.44 0.5932 0.9992 1981343 ChemDiv1_024932 CCOc1ccc(/N=C\C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N07 compound treatment 726604.0 246000.0 0.51 664089.0 199000.0 0.43 0.6632 0.9966 1981344 ChemDiv1_024933 COc1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N08 compound treatment 723097.0 242000.0 0.5 682210.0 217000.0 0.47 0.6858 0.9995 1981345 ChemDiv1_024934 Cc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(Br)cc6)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N09 compound treatment 750156.0 269000.0 0.56 676027.0 211000.0 0.46 0.7158 0.9951 1981346 ChemDiv1_024935 N#CC1=C(/N=C/c2ccccc2)c3ccccc3CC41CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N10 compound treatment 1993980.0 1510000.0 3.12 2268189.0 1800000.0 3.9 4.9681 0.9939 1981347 ChemDiv1_024936 O=c1c2ccc(N/N=C/c3c4ccccc4cc5ccccc35)c6cccc(c7nc8ccccc8n17)c62 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N11 compound treatment 795651.0 315000.0 0.65 836179.0 371000.0 0.8 1.0273 0.9945 1981348 ChemDiv1_024937 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccc(F)c3)C(C#N)(C#N)[C@H]4C=Cc5cc(Cl)ccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N12 compound treatment 653402.0 173000.0 0.36 647644.0 182000.0 0.39 0.5311 0.9987 1163185 ChemDiv1_024938 O=C(Nc1ccc2OCCOc2c1)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N13 compound treatment 817494.0 337000.0 0.7 774551.0 309000.0 0.67 0.9649 0.9998 1516002 ChemDiv1_024939 Cc1cccc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4cccc(C)c4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N14 compound treatment 691582.0 211000.0 0.44 665490.0 200000.0 0.43 0.6142 1.0 1411994 ChemDiv1_024940 CC1(C)CC(C)(NC(=S)N1)c2ccc(O)cc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N15 compound treatment 770194.0 290000.0 0.6 676102.0 211000.0 0.46 0.7452 0.9911 1981349 ChemDiv1_024941 Clc1ccc(cc1)C(=O)N/N=C/c2cn(nc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N16 compound treatment 713929.0 233000.0 0.48 647696.0 182000.0 0.39 0.6196 0.9951 1455534 ChemDiv1_024942 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5cccc(Cl)c5)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N17 compound treatment 752296.0 272000.0 0.56 687655.0 222000.0 0.48 0.7367 0.9971 1981350 ChemDiv1_024943 OC(=O)c1ccccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6[N+](=O)[O-])c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N18 compound treatment 728057.0 247000.0 0.51 664624.0 199000.0 0.43 0.6661 0.9965 1655948 ChemDiv1_024944 CC(C)(C)C(C(Oc1ccc(Cl)cc1)n2cncn2)n3nnnc3C(N4CCCCC4)c5ccc(Cl)cc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N19 compound treatment 724150.0 243000.0 0.5 665610.0 200000.0 0.43 0.6619 0.9973 1613983 ChemDiv1_024945 Cc1ccc(cc1)N2CCN(C2c3ccc(Br)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N20 compound treatment 708905.0 228000.0 0.47 671889.0 207000.0 0.45 0.6493 0.9997 1631037 ChemDiv1_024946 Cc1ccc(NC(=O)Cc2c(Sc3ccccc3)c4ccccc4n2Cc5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N21 compound treatment 734607.0 254000.0 0.52 683593.0 218000.0 0.47 0.7047 0.9987 1434092 ChemDiv1_024947 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(Br)cc3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N22 compound treatment 777685.0 297000.0 0.61 720125.0 255000.0 0.55 0.8235 0.9986 1981351 ChemDiv1_024948 Fc1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N23 mock treatment 713749.0 233000.0 0.48 658515.0 193000.0 0.42 0.6359 0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 N24 mock treatment 437223.0 -43400.0 -0.09 391881.0 -73500.0 -0.16 -0.1758 -0.9633 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O01 compound treatment 642702.0 162000.0 0.33 562613.0 97300.0 0.21 0.3854 0.9751 1981352 ChemDiv1_024949 COc1cc(/C=C\2/C(=N)N3C(=CSC3=NC2=O)c4ccccc4)ccc1OCCOc5ccccc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O02 compound treatment 662444.0 182000.0 0.38 623168.0 158000.0 0.34 0.5069 0.9989 1981353 ChemDiv1_024950 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4cccc(F)c4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O03 compound treatment 714077.0 233000.0 0.48 685768.0 220000.0 0.48 0.678 1.0 1981354 ChemDiv1_024951 COc1ccc2S/C(=C\c3sc4ccccc4[n+]3C)/N(CCCS(=O)(=O)O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O04 compound treatment 693944.0 213000.0 0.44 653158.0 188000.0 0.41 0.5988 0.9992 1981355 ChemDiv1_024952 Clc1ccc2N3[C@@H]([C@@H](c4ccccc4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O05 compound treatment 686403.0 206000.0 0.42 653840.0 188000.0 0.41 0.5888 0.9998 1981356 ChemDiv1_024953 Cc1ccc(o1)c2ccccc2NC(=O)CSc3nnc4-c5cccc6cccc(-c4n3)c56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O06 compound treatment 731628.0 251000.0 0.52 676476.0 211000.0 0.46 0.6894 0.998 1981357 ChemDiv1_024954 COc1cccc(c1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O07 compound treatment 694004.0 213000.0 0.44 663149.0 198000.0 0.43 0.6141 0.9999 1380621 ChemDiv1_024955 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O08 compound treatment 773626.0 293000.0 0.6 691631.0 226000.0 0.49 0.7739 0.9945 1981358 ChemDiv1_024956 Cc1ccc(cc1)C(=O)[C@H]2[C@H](c3ccc(F)cc3)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O09 compound treatment 686422.0 206000.0 0.42 633820.0 168000.0 0.36 0.5582 0.9971 1269207 ChemDiv1_024957 Fc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O10 compound treatment 670130.0 189000.0 0.39 610636.0 145000.0 0.31 0.4989 0.9942 1155113 ChemDiv1_024958 CON1C(N(CC1=O)C(=O)c2ccccc2)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O11 compound treatment 696016.0 215000.0 0.44 644931.0 180000.0 0.39 0.5892 0.9978 1613673 ChemDiv1_024959 COc1ccc(NC(=O)c2c(NC(=O)c3ccccc3Br)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O12 compound treatment 661695.0 181000.0 0.37 589700.0 124000.0 0.27 0.4546 0.987 1981359 ChemDiv1_024960 [O-][N+](=O)c1ccc(cc1)c2nc([nH]c2c3ccccc3)c4cccc(c4)c5nc(c([nH]5)c6ccccc6)c7ccc(cc7)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O13 compound treatment 684960.0 204000.0 0.42 613852.0 149000.0 0.32 0.5255 0.991 1981360 ChemDiv1_024961 CCOC(=O)c1ccc(cc1)N2C(=O)CC(NCc3ccc(OC)cc3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O14 compound treatment 649357.0 169000.0 0.35 603915.0 139000.0 0.3 0.4583 0.9972 1981361 ChemDiv1_024962 Cc1ccc(N/C(=N/OC(=O)c2ccccc2)/c3nonc3N)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O15 compound treatment 718773.0 238000.0 0.49 659258.0 194000.0 0.42 0.6443 0.9969 1981362 ChemDiv1_024963 CN(C)Cc1c(O)ccc2oc(CSCc3ccccc3)c(C(=O)C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O16 compound treatment 712112.0 231000.0 0.48 665651.0 200000.0 0.43 0.6444 0.9988 1191326 ChemDiv1_024964 Cc1ccc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccc(C)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O17 compound treatment 698121.0 217000.0 0.45 666580.0 201000.0 0.44 0.6254 0.9999 1441104 ChemDiv1_024965 CCCN(CCC)c1ncnc2c1sc3nc(CCC)c4COC(C)(C)Cc4c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O18 compound treatment 670428.0 190000.0 0.39 622629.0 157000.0 0.34 0.5177 0.9976 1656497 ChemDiv1_024966 CC(C)CN1C(=O)N(C(n2oc(=O)n(c3cccc(Cl)c3)c2=O)C1(C)C)c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O19 compound treatment 818353.0 338000.0 0.7 721983.0 257000.0 0.56 0.8857 0.9937 1981363 ChemDiv1_024967 Clc1ccc([C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O20 compound treatment 664487.0 184000.0 0.38 633442.0 168000.0 0.36 0.5256 0.9998 1981364 ChemDiv1_024968 CCCCOc1ccc(cc1)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O21 compound treatment 715278.0 235000.0 0.48 679424.0 214000.0 0.46 0.6701 0.9998 1349302 ChemDiv1_024969 COc1ccc(OC)c(c1)C2C(N3C=Cc4ccccc4C3C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O22 compound treatment 683369.0 203000.0 0.42 622608.0 157000.0 0.34 0.5366 0.9948 1981365 ChemDiv1_024970 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccc(F)cc2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O23 mock treatment 693316.0 213000.0 0.44 638496.0 173000.0 0.37 0.5754 0.9969 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 O24 mock treatment 270169.0 -211000.0 -0.43 411536.0 -53800.0 -0.12 -0.3896 -0.866 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P01 compound treatment 655844.0 175000.0 0.36 555652.0 90300.0 0.2 0.3939 0.9583 1164753 ChemDiv1_024971 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(Cl)cc3Cl)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P02 compound treatment 637750.0 157000.0 0.32 602708.0 137000.0 0.3 0.4395 0.9991 1981366 ChemDiv1_024972 FC(F)(F)c1cccc(/N=C/2\NC(=S)N(c3cccc(Cl)c3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P03 compound treatment 687865.0 207000.0 0.43 642197.0 177000.0 0.38 0.5731 0.9985 1981367 ChemDiv1_024973 Cc1ccc(cc1)S(=O)(=O)Oc2ccc3ccccc3c2/C=N/NC(=O)CC(=O)N\N=C\c4c(OS(=O)(=O)c5ccc(C)cc5)ccc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P04 compound treatment 624797.0 144000.0 0.3 590466.0 125000.0 0.27 0.4019 0.9989 1981368 ChemDiv1_024974 COc1ccc(Br)cc1/C=N/c2c(C)n(C)n(c3ccccc3)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P05 compound treatment 625773.0 145000.0 0.3 585354.0 120000.0 0.26 0.3955 0.9975 1222245 ChemDiv1_024975 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccccc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P06 compound treatment 763914.0 283000.0 0.58 702139.0 237000.0 0.51 0.7759 0.9978 1981369 ChemDiv1_024976 Oc1ccc(Br)cc1/C=C/2\SC(=NC2=O)N3CCN(CC3)C4=NC(=O)\C(=C\c5cc(Br)ccc5O)\S4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P07 compound treatment 684693.0 204000.0 0.42 615634.0 150000.0 0.33 0.5278 0.9919 1981370 ChemDiv1_024977 NC1=C(C#N)C2=CCCC[C@H]2[C@H](c3ccccc3C(F)(F)F)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P08 compound treatment 659132.0 178000.0 0.37 601449.0 136000.0 0.29 0.4688 0.9939 1981371 ChemDiv1_024978 CCOC(=O)C1(C#N)C(C(N2C=C(C=CC21)C(=O)N)C(=O)N)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P09 compound treatment 668626.0 188000.0 0.39 631035.0 166000.0 0.36 0.5279 0.9992 1981372 ChemDiv1_024979 O=C(NC(=S)NC1=C(C#N)C2(CCCC2)Cc3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P10 compound treatment 652315.0 172000.0 0.35 601844.0 137000.0 0.3 0.4595 0.9959 1444387 ChemDiv1_024980 NC(=O)CSc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P11 compound treatment 845749.0 365000.0 0.75 768814.0 303000.0 0.66 0.9973 0.9977 1981373 ChemDiv1_024981 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccc(C)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P12 compound treatment 659609.0 179000.0 0.37 603341.0 138000.0 0.3 0.4724 0.9944 1642872 ChemDiv1_024982 O=c1[nH]c(=S)[nH]c2-c3ccccc3CC4(CCCCC4)c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P13 compound treatment 647427.0 167000.0 0.34 593789.0 128000.0 0.28 0.44 0.9944 1981374 ChemDiv1_024983 [O-][N+](=O)c1cccc(c1)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P14 compound treatment 654097.0 173000.0 0.36 630491.0 165000.0 0.36 0.5059 1.0 1597804 ChemDiv1_024984 CC1(C)CC(C)(N(C(=S)N1)c2ccccc2)c3ccc(O)cc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P15 compound treatment 658808.0 178000.0 0.37 616783.0 151000.0 0.33 0.4918 0.9984 1330473 ChemDiv1_024985 COc1ccc(cc1OC)C(C2=C(O)CCCC2=O)C3=C(O)CCCC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P16 compound treatment 663916.0 183000.0 0.38 646763.0 181000.0 0.39 0.5451 0.9998 1920258 ChemDiv1_024986 Cc1cc([N+](=O)[O-])c(C)c(c1)c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P17 compound treatment 659609.0 179000.0 0.37 624854.0 160000.0 0.35 0.5053 0.9994 1981375 ChemDiv1_024987 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc([N+](=O)[O-])c(Cl)cc4Cl)ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P18 compound treatment 676216.0 196000.0 0.4 634296.0 169000.0 0.37 0.544 0.9988 1375029 ChemDiv1_024988 CN1CCC(OC(=O)C)(C2CCCC21)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P19 compound treatment 696901.0 216000.0 0.45 644345.0 179000.0 0.39 0.5896 0.9975 1259158 ChemDiv1_024989 OC1=C(C(C2C(=O)CCCC2=O)c3ccc(Cl)cc3)C(=O)CCC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P20 compound treatment 664255.0 184000.0 0.38 622853.0 158000.0 0.34 0.509 0.9986 1981376 ChemDiv1_024990 CCC(CCC(C)C1CCC2C3CC=C4CC(CCC4(C)C3CCC12C)OC(=O)c5ccccc5)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P21 compound treatment 683268.0 203000.0 0.42 612990.0 148000.0 0.32 0.5217 0.9912 1981377 ChemDiv1_024991 [O-][N+](=O)c1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P22 compound treatment 685740.0 205000.0 0.42 649527.0 184000.0 0.4 0.5812 0.9995 1981378 ChemDiv1_024992 Clc1ccc(cc1Cl)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P23 mock treatment 672662.0 192000.0 0.4 583440.0 118000.0 0.26 0.461 0.9775 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.657 P24 mock treatment 436270.0 -44400.0 -0.09 453967.0 -11400.0 -0.02 -0.0822 -0.8663 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A01 compound treatment 732344.0 251000.0 0.52 665610.0 185000.0 0.4 0.6485 0.9919 1147811 ChemDiv1_024993 CCOc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A02 compound treatment 568486.0 86800.0 0.18 501132.0 20200.0 0.04 0.1576 0.8544 1981379 ChemDiv1_024994 [O-][N+](=O)c1cc2C(C=O)c3cc(cc([N+](=O)[O-])c3-c2c(c1)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A03 compound treatment 659939.0 178000.0 0.37 594463.0 114000.0 0.25 0.4339 0.9807 1981380 ChemDiv1_024995 CC(C)CN1C(=O)N(C(n2oc(=O)n(c3ccc(Cl)c(Cl)c3)c2=O)C1(C)C)c4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A04 compound treatment 700960.0 219000.0 0.45 614799.0 134000.0 0.29 0.5249 0.9767 1981381 ChemDiv1_024996 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccc(I)c3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A05 compound treatment 659123.0 177000.0 0.37 617248.0 136000.0 0.29 0.4676 0.9942 1981382 ChemDiv1_024997 CC1(C)SC(=S)N(/N=C/c2ccco2)C1N(O)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A06 compound treatment 664886.0 183000.0 0.38 622581.0 142000.0 0.31 0.4842 0.9946 1287579 ChemDiv1_024998 OC1=C(C(N(C1=O)c2ccc(Br)cn2)c3ccc(Br)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A07 compound treatment 703818.0 222000.0 0.46 653955.0 173000.0 0.37 0.589 0.9949 1981383 ChemDiv1_024999 CCOC(=O)C1=CN2[C@@H]([C@H]([C@@H]([C@@H]2C=C1)C(=O)C3(CC4CC5CC(C4)C3)C5)c6ccccc6)C(=O)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A08 compound treatment 708114.0 226000.0 0.47 642539.0 162000.0 0.35 0.5778 0.9898 1981384 ChemDiv1_025000 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(OC(=O)c5ccc(Br)cc5)cc4)c(=O)n(c6ccccc6)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A09 compound treatment 820726.0 339000.0 0.7 720560.0 240000.0 0.52 0.8616 0.9891 1981385 ChemDiv1_025001 Fc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A10 compound treatment 703166.0 221000.0 0.46 634591.0 154000.0 0.33 0.5584 0.9878 1981386 ChemDiv1_025002 Cc1cc(C)c(N2C(=O)C3C(C4C(=O)CC3c5ccccc45)C2=O)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A11 compound treatment 682832.0 201000.0 0.42 634158.0 153000.0 0.33 0.5281 0.9938 1981387 ChemDiv1_025003 CSC1=N/C(=N\c2cccc(c2)C(F)(F)F)/C3(CCCCC3)N1c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A12 compound treatment 703715.0 222000.0 0.46 624021.0 143000.0 0.31 0.543 0.9818 1176132 ChemDiv1_025004 CN(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A13 compound treatment 580028.0 98300.0 0.2 532096.0 51100.0 0.11 0.2218 0.9593 1981388 ChemDiv1_025005 COc1ccc(/C=C/2\c3cccnc3-c4ccc(C)cc24)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A14 compound treatment 708816.0 227000.0 0.47 651795.0 171000.0 0.37 0.593 0.9931 1916051 ChemDiv1_025006 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A15 compound treatment 722102.0 240000.0 0.5 658817.0 178000.0 0.38 0.6231 0.9921 1981389 ChemDiv1_025007 CCS/C=C(/NC(=O)c1ccc(C)cc1)\[P+](c2ccccc2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A16 compound treatment 720975.0 239000.0 0.49 622877.0 142000.0 0.31 0.5665 0.9739 1389409 ChemDiv1_025008 CC1(C)C(N(O)C(=O)NC2CCCCC2)N(C3CCCCC3)C(=O)N1CCC(=O)NN 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A17 compound treatment 705670.0 224000.0 0.46 680742.0 200000.0 0.43 0.6327 0.9994 1981390 ChemDiv1_025009 CCOC(=O)c1cc2/C(=N/c3cccc4ccccc34)/c5cc(ccc5-c2nc1C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A18 compound treatment 697424.0 216000.0 0.45 641356.0 160000.0 0.35 0.5604 0.9924 1981391 ChemDiv1_025010 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5cccc(Cl)c5C)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A19 compound treatment 717043.0 235000.0 0.49 636836.0 156000.0 0.34 0.5821 0.9841 1981392 ChemDiv1_025011 Cc1cccc(/N=C\2/c3ccccc3-c4ncccc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A20 compound treatment 674297.0 193000.0 0.4 625615.0 145000.0 0.31 0.5025 0.993 1693425 ChemDiv1_025012 C1CN(C(N1c2ccccc2)c3cccc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A21 compound treatment 677050.0 195000.0 0.4 627882.0 147000.0 0.32 0.51 0.9931 1981393 ChemDiv1_025013 COc1ccc(/C=C/2\c3cc(C)ccc3-c4nc5ccccc5cc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A22 compound treatment 642492.0 161000.0 0.33 628533.0 148000.0 0.32 0.4606 0.9998 1159078 ChemDiv1_025014 COc1cccc(C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A23 mock treatment 623864.0 142000.0 0.29 591620.0 111000.0 0.24 0.3769 0.9949 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 A24 mock treatment 249697.0 -232000.0 -0.48 214292.0 -267000.0 -0.58 -0.7467 -0.9957 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B01 compound treatment 521053.0 39400.0 0.08 578079.0 97100.0 0.21 0.2061 0.9145 1781402 ChemDiv1_025015 CC1(C)CC(=O)C2=C(C1)C(Nc3ccc4ccccc4c23)c5ccc(o5)c6cc(ccc6Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B02 compound treatment 654909.0 173000.0 0.36 623147.0 142000.0 0.31 0.4705 0.9972 1419897 ChemDiv1_025016 Cc1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B03 compound treatment 695836.0 214000.0 0.44 664318.0 183000.0 0.4 0.5932 0.9986 1981394 ChemDiv1_025017 Cc1ccccc1C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B04 compound treatment 690449.0 209000.0 0.43 659240.0 178000.0 0.39 0.5776 0.9985 1981395 ChemDiv1_025018 CCc1ccccc1N2C(=O)C3CCC(C)(C2=O)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B05 compound treatment 711356.0 230000.0 0.47 685423.0 204000.0 0.44 0.6482 0.9994 1355802 ChemDiv1_025019 COC(=O)C1=C(N)n2c(=O)c(=Cc3cc(Br)ccc3F)sc2=C(C#N)C1c4cc(Br)ccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B06 compound treatment 714188.0 233000.0 0.48 667152.0 186000.0 0.4 0.6243 0.9962 1981396 ChemDiv1_025020 Cc1ccc(cc1C)N2C(=O)C3CCC(C)(C2=O)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B07 compound treatment 819807.0 338000.0 0.7 768409.0 287000.0 0.62 0.9335 0.9984 1981397 ChemDiv1_025021 CC(=O)[C@H]1[C@H](c2ccc(F)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B08 compound treatment 739654.0 258000.0 0.53 701398.0 220000.0 0.48 0.7139 0.9985 1606520 ChemDiv1_025022 COc1ccc(NC(=O)Cc2c(Sc3ccccc3)c4ccccc4n2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B09 compound treatment 925866.0 444000.0 0.92 822328.0 341000.0 0.74 1.1708 0.9943 1981398 ChemDiv1_025023 Clc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5cc(Cl)ccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B10 compound treatment 718142.0 236000.0 0.49 673239.0 192000.0 0.42 0.6394 0.9968 1981399 ChemDiv1_025024 Cc1cccc(/N=C/2\NC(=S)N(c3ccc(C)cc3Br)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B11 compound treatment 737171.0 255000.0 0.53 698580.0 218000.0 0.47 0.706 0.9984 1981400 ChemDiv1_025025 CCOC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B12 compound treatment 735430.0 254000.0 0.52 678689.0 198000.0 0.43 0.673 0.995 1163992 ChemDiv1_025026 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccncc3)sc2=C(C#N)C1c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B13 compound treatment 747640.0 266000.0 0.55 710450.0 229000.0 0.5 0.7394 0.9988 1981401 ChemDiv1_025027 Cc1ccccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(Br)cc6)c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B14 compound treatment 897779.0 416000.0 0.86 816173.0 335000.0 0.73 1.1204 0.9965 1981402 ChemDiv1_025028 CC(C)(C)C(=O)[C@H]1[C@H](c2cccc(Br)c2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B15 compound treatment 753206.0 272000.0 0.56 714522.0 234000.0 0.51 0.7538 0.9987 1981403 ChemDiv1_025029 Cc1cccc(c1)n2nnnc2C3(CCCCC3)/N=C/c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B16 compound treatment 745220.0 264000.0 0.54 694508.0 214000.0 0.46 0.7115 0.9967 1981404 ChemDiv1_025030 Cc1cccc(/N=C/2\NC(=S)N(c3ccc(Cl)cc3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B17 compound treatment 767504.0 286000.0 0.59 728980.0 248000.0 0.54 0.7968 0.9989 1663997 ChemDiv1_025031 CCCOC1OC(=O)c2c1ccc(OC)c2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B18 compound treatment 753689.0 272000.0 0.56 685568.0 205000.0 0.44 0.7102 0.9931 1981405 ChemDiv1_025032 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3Cl)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B19 compound treatment 797096.0 315000.0 0.65 693022.0 212000.0 0.46 0.785 0.9854 1981406 ChemDiv1_025033 CCOc1cccc2C3=C(SC(=C(C(=O)OC)C43SC(=C(S4)C(=O)OC)C(=O)OC)C(=O)OC)C(C)(C)N(C(=O)c5ccc(cc5)[N+](=O)[O-])c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B20 compound treatment 723276.0 242000.0 0.5 691186.0 210000.0 0.46 0.6744 0.999 1981407 ChemDiv1_025034 Brc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)C(=O)c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B21 compound treatment 750856.0 269000.0 0.56 717133.0 236000.0 0.51 0.7544 0.9991 1981408 ChemDiv1_025035 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3)C42CCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B22 compound treatment 725495.0 244000.0 0.5 674156.0 193000.0 0.42 0.6516 0.9958 1981409 ChemDiv1_025036 COc1cc(ccc1c2ccc(/C=N/c3c(nc4ccccn34)c5ccco5)o2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B23 mock treatment 693276.0 212000.0 0.44 658363.0 177000.0 0.38 0.5804 0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 B24 mock treatment 232073.0 -250000.0 -0.52 221161.0 -260000.0 -0.56 -0.762 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C01 compound treatment 579819.0 98100.0 0.2 662780.0 182000.0 0.39 0.4215 0.9523 1292505 ChemDiv1_025037 COc1cccc(c1)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C02 compound treatment 622014.0 140000.0 0.29 574599.0 93600.0 0.2 0.3482 0.9847 1981410 ChemDiv1_025038 CC(=O)OC=C1c2cc(cc([N+](=O)[O-])c2-c3c1cc(cc3[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C03 compound treatment 725446.0 244000.0 0.5 694025.0 213000.0 0.46 0.6819 0.9991 1981411 ChemDiv1_025039 COc1ccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C04 compound treatment 753507.0 272000.0 0.56 745427.0 264000.0 0.57 0.8015 1.0 1981412 ChemDiv1_025040 COc1cc(cc(OC)c1OC)[C@@H]2[C@H](N3[C@H](C=Cc4c3ccc5ccccc45)C2(C#N)C#N)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C05 compound treatment 747564.0 266000.0 0.55 727283.0 246000.0 0.53 0.7651 0.9999 1981413 ChemDiv1_025041 CC1(C)SC(=S)N(/N=C/c2ccco2)C1N(O)C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C06 compound treatment 719969.0 238000.0 0.49 687101.0 206000.0 0.45 0.6633 0.9988 1528050 ChemDiv1_025042 COc1ccc(cc1OC)C2N(C)C(=O)C(=C2C(=O)c3ccc(C)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C07 compound treatment 966895.0 485000.0 1.0 763008.0 282000.0 0.61 1.1399 0.9718 1981414 ChemDiv1_025043 NC1=C(C#N)C(c2ccc(cc2)[N+](=O)[O-])c3c(O)ccc(/C=N\c4ccccc4)c3O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C08 compound treatment 745848.0 264000.0 0.55 733741.0 253000.0 0.55 0.7725 1.0 1459772 ChemDiv1_025044 COc1ccc(cc1)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C09 compound treatment 782198.0 301000.0 0.62 772722.0 292000.0 0.63 0.8852 1.0 1588648 ChemDiv1_025045 CCc1ccc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccc(CC)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C10 compound treatment 715480.0 234000.0 0.48 726451.0 245000.0 0.53 0.717 0.9988 1981415 ChemDiv1_025046 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C11 compound treatment 775286.0 294000.0 0.61 736452.0 255000.0 0.55 0.8196 0.999 1137164 ChemDiv1_025047 Cc1ccc2n(C)c(CC(=O)Nc3ccccc3)c(Sc4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C12 compound treatment 715623.0 234000.0 0.48 707674.0 227000.0 0.49 0.6885 1.0 1981416 ChemDiv1_025048 ClCC1=Nc2ccccc2C(O1)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C13 compound treatment 715008.0 233000.0 0.48 668298.0 187000.0 0.41 0.6273 0.9963 1981417 ChemDiv1_025049 Brc1ccc(/C=C\2/c3ccccc3-c4nc5ccccc5cc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C14 compound treatment 783048.0 301000.0 0.62 733775.0 253000.0 0.55 0.8268 0.998 1981418 ChemDiv1_025050 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C15 compound treatment 792690.0 311000.0 0.64 734467.0 254000.0 0.55 0.842 0.9969 1981419 ChemDiv1_025051 COc1ccc(/C=N/N2C(N(O)C(=O)NC3CCCCC3)C(C)(C)SC2=S)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C16 compound treatment 816505.0 335000.0 0.69 801644.0 321000.0 0.69 0.9795 1.0 1981420 ChemDiv1_025052 Cc1ccc2nc(ccc2c1)C3=C(O)c4ccccc4C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C17 compound treatment 759172.0 277000.0 0.57 742577.0 262000.0 0.57 0.8054 1.0 1981421 ChemDiv1_025053 Cc1cnc-2c(c1)/C(=N\c3ccccc3)/c4cccc(C)c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C18 compound treatment 711440.0 230000.0 0.47 721375.0 240000.0 0.52 0.7033 0.9989 1981422 ChemDiv1_025054 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C19 compound treatment 767578.0 286000.0 0.59 721984.0 241000.0 0.52 0.7862 0.9981 1981423 ChemDiv1_025055 Cc1ccc2cc3/C(=N\c4ccccc4)/c5ccccc5-c3nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C20 compound treatment 725370.0 244000.0 0.5 716309.0 235000.0 0.51 0.7159 1.0 1496029 ChemDiv1_025056 Clc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C21 compound treatment 743367.0 262000.0 0.54 704985.0 224000.0 0.48 0.7248 0.9985 1125801 ChemDiv1_025057 Cc1ccc2cc3Cc4ccccc4-c3nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C22 compound treatment 715851.0 234000.0 0.48 712490.0 232000.0 0.5 0.6962 0.9998 1499362 ChemDiv1_025058 COc1ccc(cc1OC)C(C2=C(O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C23 mock treatment 721519.0 240000.0 0.5 692376.0 211000.0 0.46 0.6737 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 C24 mock treatment 235288.0 -246000.0 -0.51 225727.0 -255000.0 -0.55 -0.7503 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D01 compound treatment 552667.0 71000.0 0.15 570378.0 89400.0 0.19 0.2405 0.9906 1981424 ChemDiv1_025059 Cc1ccc(N/C(=N\OCc2ccc(Cl)cc2)/c3nonc3N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D02 compound treatment 686470.0 205000.0 0.42 630327.0 149000.0 0.32 0.5275 0.9912 1781330 ChemDiv1_025060 OC1=C(C(N(C1=O)c2nccs2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D03 compound treatment 705093.0 223000.0 0.46 657672.0 177000.0 0.38 0.5966 0.9957 1981425 ChemDiv1_025061 CCCCOc1ccc(/C=C\2/CCCC\C(=C\c3ccc(OCCCC)cc3)\C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D04 compound treatment 721487.0 240000.0 0.5 704506.0 224000.0 0.48 0.6922 0.9999 1340856 ChemDiv1_025062 Cc1ccc(cc1)C(=O)Nc2ccc3C4C=CCC4CN5CC6CC=CC6c2c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D05 compound treatment 736857.0 255000.0 0.53 696755.0 216000.0 0.47 0.7027 0.9982 1610075 ChemDiv1_025063 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(Br)cc3)sc2=C(C#N)C1c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D06 compound treatment 726987.0 245000.0 0.51 722979.0 242000.0 0.52 0.7285 0.9999 1518098 ChemDiv1_025064 Fc1ccccc1C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D07 compound treatment 822384.0 341000.0 0.7 779443.0 298000.0 0.65 0.9541 0.9991 1981426 ChemDiv1_025065 CC(C)(C)C(=O)[C@H]1[C@H](c2ccsc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D08 compound treatment 737139.0 255000.0 0.53 706699.0 226000.0 0.49 0.7184 0.9993 1981427 ChemDiv1_025066 Ic1cccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D09 compound treatment 847837.0 366000.0 0.76 788648.0 308000.0 0.67 1.0054 0.998 1981428 ChemDiv1_025067 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5cc(Cl)ccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D10 compound treatment 755222.0 274000.0 0.56 726041.0 245000.0 0.53 0.7744 0.9995 1981429 ChemDiv1_025068 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3Cl)C42CCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D11 compound treatment 871055.0 389000.0 0.8 808550.0 328000.0 0.71 1.0697 0.998 1981430 ChemDiv1_025069 O=C(COC(=O)c1ccc2C3C=CCC3CN4CC5CC=CC5c1c42)c6ccc(cc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D12 compound treatment 718693.0 237000.0 0.49 701755.0 221000.0 0.48 0.6839 0.9999 1187623 ChemDiv1_025070 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(OC)c(OC)c3)sc2=C(C#N)C1c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D13 compound treatment 761918.0 280000.0 0.58 725222.0 244000.0 0.53 0.7829 0.999 1923157 ChemDiv1_025071 COc1ccc(/C=C/C(=O)C2(O)CCCCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D14 compound treatment 1043609.0 562000.0 1.16 1004621.0 524000.0 1.13 1.6217 0.9999 1981431 ChemDiv1_025072 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccnc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D15 compound treatment 776646.0 295000.0 0.61 723760.0 243000.0 0.53 0.8022 0.9973 1981432 ChemDiv1_025073 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4cc(Cl)cc([N+](=O)[O-])c4O)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D16 compound treatment 742714.0 261000.0 0.54 686852.0 206000.0 0.45 0.6961 0.9955 1981433 ChemDiv1_025074 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCCC3)N1c4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D17 compound treatment 765769.0 284000.0 0.59 738159.0 257000.0 0.56 0.8083 0.9997 1981434 ChemDiv1_025075 CC(N1C(=S)N/C(=N\c2cc(Cl)ccc2C)/C31CCCCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D18 compound treatment 735833.0 254000.0 0.52 695394.0 214000.0 0.46 0.6992 0.9981 1981435 ChemDiv1_025076 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCCC3)N1c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D19 compound treatment 763890.0 282000.0 0.58 724101.0 243000.0 0.53 0.7841 0.9987 1981436 ChemDiv1_025077 CCCc1ccc(cc1)c2c3C(=O)c4ccccc4C(=O)c3c(c5ccccc5)n2c6ccc(N)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D20 compound treatment 736991.0 255000.0 0.53 702231.0 221000.0 0.48 0.7113 0.9989 1981437 ChemDiv1_025078 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)C(=O)c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D21 compound treatment 767388.0 286000.0 0.59 736957.0 256000.0 0.55 0.8088 0.9995 1981438 ChemDiv1_025079 COc1ccc(cc1)N2C(=S)N/C(=N\c3cc(Cl)ccc3C)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D22 compound treatment 729564.0 248000.0 0.51 803908.0 323000.0 0.7 0.8561 0.9882 1981439 ChemDiv1_025080 [O-][N+](=O)c1cc(ccc1Cl)c2ccc(/C=N/c3c(nc4ccccn34)c5ccco5)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D23 mock treatment 719593.0 238000.0 0.49 677321.0 196000.0 0.43 0.6478 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 D24 mock treatment 224041.0 -258000.0 -0.53 220931.0 -260000.0 -0.56 -0.774 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E01 compound treatment 530970.0 49300.0 0.1 593665.0 113000.0 0.24 0.2444 0.9248 1981440 ChemDiv1_025081 Cc1ccc(C)c(NC=C2C(=O)N(C(=S)N(C2=O)c3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E02 compound treatment 608251.0 127000.0 0.26 605274.0 124000.0 0.27 0.375 0.9999 1981441 ChemDiv1_025082 CN(C)c1cc2C(=O)c3cc(cc([N+](=O)[O-])c3-c2c(c1)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E03 compound treatment 689442.0 208000.0 0.43 711015.0 230000.0 0.5 0.6554 0.9972 1981442 ChemDiv1_025083 COc1c(CC=C)cccc1/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E04 compound treatment 763147.0 281000.0 0.58 783162.0 302000.0 0.65 0.8734 0.9983 1981443 ChemDiv1_025084 COc1cc(cc(OC)c1OC)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E05 compound treatment 1727436.0 1250000.0 2.57 1639402.0 1160000.0 2.51 3.5913 0.9999 1981444 ChemDiv1_025085 CC1(C)SC(=S)N(/N=C/C=C/c2ccc(o2)[N+](=O)[O-])C1N(O)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E06 compound treatment 714997.0 233000.0 0.48 702705.0 222000.0 0.48 0.6799 1.0 1981445 ChemDiv1_025086 OC1=C(C(N(C1=O)c2ccc(Br)cn2)c3ccc(cc3)[N+](=O)[O-])C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E07 compound treatment 1347504.0 866000.0 1.79 998891.0 518000.0 1.12 2.0565 0.9747 1981446 ChemDiv1_025087 COc1ccccc1/N=C\c2ccc(O)c3C(C(=C(N)Oc23)C#N)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E08 compound treatment 757944.0 276000.0 0.57 730603.0 250000.0 0.54 0.7853 0.9996 1929841 ChemDiv1_025088 Cc1c(NC(=O)/C=C/c2ccccc2)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E09 compound treatment 782389.0 301000.0 0.62 754643.0 274000.0 0.59 0.8578 0.9997 1981447 ChemDiv1_025089 NC1=C(C#N)C(C(=c2sc(=Cc3ccccc3I)c(=O)n12)C#N)c4ccccc4I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E10 compound treatment 739783.0 258000.0 0.53 720571.0 240000.0 0.52 0.7435 0.9999 1662670 ChemDiv1_025090 COc1ccc2C(O)OC(=O)c2c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E11 compound treatment 704173.0 222000.0 0.46 729410.0 248000.0 0.54 0.705 0.9969 1981448 ChemDiv1_025091 Cc1ccccc1/N=C\2/c3ccccc3-c4nc5ccccc5cc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E12 compound treatment 722535.0 241000.0 0.5 716835.0 236000.0 0.51 0.7126 0.9999 1981449 ChemDiv1_025092 Clc1ccc(C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E13 compound treatment 739504.0 258000.0 0.53 729570.0 249000.0 0.54 0.7568 1.0 1981450 ChemDiv1_025093 Cc1ccc(Nc2nc3nonc3[nH]c2=N/N=C/c4ccc(Cl)cc4Cl)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E14 compound treatment 762303.0 281000.0 0.58 714807.0 234000.0 0.51 0.7675 0.9977 1981451 ChemDiv1_025094 CN1C2C(N(C)C1=O)N(C)C(=O)N2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E15 compound treatment 759740.0 278000.0 0.57 751775.0 271000.0 0.59 0.8203 0.9999 1981452 ChemDiv1_025095 [O-][N+](=O)c1ccc(cc1)C2=Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E16 compound treatment 705273.0 224000.0 0.46 714114.0 233000.0 0.5 0.6832 0.999 1933122 ChemDiv1_025096 COc1ccc(/C=C/C(=O)C2(C)CCCCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E17 compound treatment 756062.0 274000.0 0.57 755713.0 275000.0 0.59 0.821 0.9997 1981453 ChemDiv1_025097 Cc1ccc2/C(=N/c3ccccc3)/c4cc5cccc(C)c5nc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E18 compound treatment 729444.0 248000.0 0.51 703407.0 222000.0 0.48 0.7021 0.9995 1144675 ChemDiv1_025098 CON1C(=O)CN(C(=O)c2ccccc2)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E19 compound treatment 722930.0 241000.0 0.5 681535.0 201000.0 0.43 0.6591 0.9977 1171924 ChemDiv1_025099 Cc1cccc2cc3C(=O)c4ccccc4-c3nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E20 compound treatment 712606.0 231000.0 0.48 696192.0 215000.0 0.47 0.6665 0.9999 1178824 ChemDiv1_025100 Cc1ccc(cc1)C(=O)OC2CC(OC2CO)n3cc(C)c(=O)[nH]c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E21 compound treatment 739199.0 258000.0 0.53 707912.0 227000.0 0.49 0.7232 0.9992 1981454 ChemDiv1_025101 COc1ccc(cc1)/C(=N\NC(=O)c2ccccc2)/C3C(=NN(C3=O)c4ccccc4)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E22 compound treatment 715269.0 234000.0 0.48 705603.0 225000.0 0.49 0.6848 1.0 1981455 ChemDiv1_025102 CCCCCCOc1ccc(cc1)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E23 mock treatment 726626.0 245000.0 0.51 700996.0 220000.0 0.48 0.6943 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 E24 mock treatment 230942.0 -251000.0 -0.52 235392.0 -246000.0 -0.53 -0.7418 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F01 compound treatment 549364.0 67700.0 0.14 594799.0 114000.0 0.25 0.273 0.9639 1981456 ChemDiv1_025103 Cc1ccc(N/C(=N\OCc2ccccc2Cl)/c3nonc3N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F02 compound treatment 653849.0 172000.0 0.36 647892.0 167000.0 0.36 0.5068 1.0 1981457 ChemDiv1_025104 COc1ccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F03 compound treatment 708405.0 227000.0 0.47 693610.0 213000.0 0.46 0.6564 1.0 1981458 ChemDiv1_025105 COc1ccc(cc1)N2C(=O)C3CCC(C)(C2=O)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F04 compound treatment 841744.0 360000.0 0.74 689586.0 209000.0 0.45 0.8449 0.9715 1981459 ChemDiv1_025106 O=C1C2C(C(CCC2c3ccccc3)c4ccccc4)C(=O)N1c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F05 compound treatment 804968.0 323000.0 0.67 715724.0 235000.0 0.51 0.8312 0.9909 1981460 ChemDiv1_025107 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccccc3I)sc2=C(C#N)C1c4ccccc4I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F06 compound treatment 698900.0 217000.0 0.45 690508.0 210000.0 0.45 0.6378 1.0 1981461 ChemDiv1_025108 CC1=NN(c2ccccc2)C3(SC(=NN3c4ccccc4)c5ccccc5)c6ccccc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F07 compound treatment 806287.0 325000.0 0.67 793295.0 312000.0 0.68 0.9518 1.0 1981462 ChemDiv1_025109 CC(C)(C)C(=O)[C@H]1[C@H](c2ccccc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F08 compound treatment 734015.0 252000.0 0.52 728496.0 248000.0 0.54 0.7472 0.9999 1779044 ChemDiv1_025110 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F09 compound treatment 782667.0 301000.0 0.62 742588.0 262000.0 0.57 0.8398 0.9989 1981463 ChemDiv1_025111 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)N(N=C(c4ccc(CC)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F10 compound treatment 740690.0 259000.0 0.53 729123.0 248000.0 0.54 0.7579 1.0 1981464 ChemDiv1_025112 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCC3)N1c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F11 compound treatment 872015.0 390000.0 0.81 939751.0 459000.0 0.99 1.2719 0.9946 1121236 ChemDiv1_025113 Brc1ccc(cc1)C(=O)COC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F12 compound treatment 840585.0 359000.0 0.74 799499.0 319000.0 0.69 1.0114 0.9994 1981465 ChemDiv1_025114 COc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F13 compound treatment 766346.0 285000.0 0.59 734882.0 254000.0 0.55 0.8041 0.9994 1981466 ChemDiv1_025115 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F14 compound treatment 2416411.0 1930000.0 3.99 2321489.0 1840000.0 3.98 5.6409 1.0 1981467 ChemDiv1_025116 CC(C)(C)C(=O)[C@@H]1[C@@H](c2ccccc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F15 compound treatment 785361.0 304000.0 0.63 751049.0 270000.0 0.58 0.8566 0.9994 1981468 ChemDiv1_025117 CC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F16 compound treatment 776827.0 295000.0 0.61 716941.0 236000.0 0.51 0.792 0.9962 1981469 ChemDiv1_025118 COc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(C)c3)/C42CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F17 compound treatment 778325.0 297000.0 0.61 746062.0 265000.0 0.57 0.8387 0.9995 1981470 ChemDiv1_025119 Cc1ccc(Cl)cc1/N=C/2\NC(=S)N(CCN3CCOCC3)C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F18 compound treatment 717982.0 236000.0 0.49 719883.0 239000.0 0.52 0.7106 0.9996 1981471 ChemDiv1_025120 Cc1cccc(/N=C/2\NC(=S)N(c3cccc(C)c3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F19 compound treatment 742331.0 261000.0 0.54 700864.0 220000.0 0.48 0.717 0.9981 1923372 ChemDiv1_025121 Cc1ccccc1N/C(=N\OCc2ccccc2)/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F20 compound treatment 1014771.0 533000.0 1.1 904766.0 424000.0 0.92 1.4268 0.9959 1498266 ChemDiv1_025122 O=C(Nc1ccccc1)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F21 compound treatment 776247.0 295000.0 0.61 749073.0 268000.0 0.58 0.8403 0.9997 1422017 ChemDiv1_025123 CC1(C)SC(=S)N(CCN2CCOCC2)C1N(O)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F22 compound treatment 747993.0 266000.0 0.55 724275.0 243000.0 0.53 0.7611 0.9998 1981472 ChemDiv1_025124 Cc1ccc(N=c2oc3ccccc3cc2c4nc5ccccc5s4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F23 mock treatment 716090.0 234000.0 0.48 669897.0 189000.0 0.41 0.6313 0.9965 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 F24 mock treatment 249361.0 -232000.0 -0.48 229465.0 -251000.0 -0.54 -0.724 -0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G01 compound treatment 523640.0 42000.0 0.09 588244.0 107000.0 0.23 0.2254 0.9096 1981473 ChemDiv1_025125 [O-][N+](=O)c1ccc(cc1)c2nc([nH]c2c3ccccc3)c4ccc(cc4)c5nc(c([nH]5)c6ccccc6)c7ccc(cc7)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G02 compound treatment 617268.0 136000.0 0.28 638970.0 158000.0 0.34 0.4397 0.995 1981474 ChemDiv1_025126 CN(C)c1ccc(/C=C/2\c3cc(ccc3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G03 compound treatment 683418.0 202000.0 0.42 708130.0 227000.0 0.49 0.6421 0.9966 1981475 ChemDiv1_025127 Brc1ccc(cc1)C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G04 compound treatment 754626.0 273000.0 0.56 712458.0 232000.0 0.5 0.7527 0.9983 1981476 ChemDiv1_025128 COc1cc(cc(OC)c1OC)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G05 compound treatment 775111.0 293000.0 0.61 729868.0 249000.0 0.54 0.8093 0.9983 1981477 ChemDiv1_025129 CCOC(=O)c1ccc(/N=C/2\NC(=S)N(c3ccccc3Cl)C42CCCCC4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G06 compound treatment 691577.0 210000.0 0.43 654110.0 173000.0 0.37 0.5714 0.9974 1981478 ChemDiv1_025130 OC1=C(C(N(C1=O)c2ccc(Br)cc2)c3ccc(Br)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G07 compound treatment 972919.0 491000.0 1.01 1104550.0 624000.0 1.35 1.6714 0.9901 1981479 ChemDiv1_025131 NC1=C(C#N)[C@H](c2ccccc2[N+](=O)[O-])c3c(O)ccc(/C=N\c4ccccc4)c3O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G08 compound treatment 766931.0 285000.0 0.59 758141.0 277000.0 0.6 0.8406 1.0 1565278 ChemDiv1_025132 Cc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G09 compound treatment 764428.0 283000.0 0.58 733462.0 253000.0 0.55 0.7992 0.9995 1224573 ChemDiv1_025133 CCON1C(N(CC1=O)C(=O)OC)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G10 compound treatment 731777.0 250000.0 0.52 726966.0 246000.0 0.53 0.7416 0.9999 1676053 ChemDiv1_025134 Cc1cccc(c1)C2(CC2C(=O)Nc3cccc(Cl)c3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G11 compound treatment 754501.0 273000.0 0.56 728381.0 247000.0 0.54 0.7769 0.9997 1981480 ChemDiv1_025135 CCOC(=O)c1cc2/C(=N/C3CCCCC3)/c4ccccc4-c2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G12 compound treatment 695224.0 214000.0 0.44 700076.0 219000.0 0.47 0.6471 0.9993 1981481 ChemDiv1_025136 N1C(OC(c2ccccc2)(c3ccccc3)c4ccccc14)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G13 compound treatment 739685.0 258000.0 0.53 738361.0 257000.0 0.56 0.7705 0.9997 1981482 ChemDiv1_025137 CC1=NN(C(=O)C1C(C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)c4ccc(cc4)[N+](=O)[O-])c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G14 compound treatment 734260.0 253000.0 0.52 706078.0 225000.0 0.49 0.7132 0.9994 1156194 ChemDiv1_025138 COc1ccc(cc1OC)C2(CCCC2)C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G15 compound treatment 778871.0 297000.0 0.61 742365.0 261000.0 0.57 0.8339 0.9992 1981483 ChemDiv1_025139 CC1Oc2ccc(cc2C3OC(c4ccccc4)(c5ccccc5)c6ccccc6N13)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G16 compound treatment 743418.0 262000.0 0.54 705965.0 225000.0 0.49 0.7264 0.9987 1981484 ChemDiv1_025140 COc1cc(ccc1OCc2ccc(Cl)cc2Cl)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G17 compound treatment 816746.0 335000.0 0.69 804023.0 323000.0 0.7 0.9835 1.0 1981485 ChemDiv1_025141 Cc1ccc-2c(c1)/C(=C/c3ccc(cc3)[N+](=O)[O-])/c4cc5ccccc5nc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G18 compound treatment 731827.0 250000.0 0.52 712148.0 231000.0 0.5 0.719 0.9999 1981486 ChemDiv1_025142 [O-][N+](=O)c1nnn(n1)[C@@H]2[C@H](CC(=CC2=O)c3cccs3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G19 compound treatment 765192.0 284000.0 0.59 730592.0 250000.0 0.54 0.7959 0.9992 1981487 ChemDiv1_025143 Cc1ccc-2c(c1)/C(=C\c3ccc(Br)cc3)/c4cc5ccccc5nc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G20 compound treatment 697974.0 216000.0 0.45 693754.0 213000.0 0.46 0.6414 0.9999 1981488 ChemDiv1_025144 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(c(OS(=O)(=O)c3ccc(C)cc3)c2)C4(C)CC(C)(C)NC(=S)N4c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G21 compound treatment 471769.0 -9910.0 -0.02 424238.0 -56700.0 -0.12 -0.1013 -0.8138 1981489 ChemDiv1_025145 CCCCCCCCCCCCOC=C1c2cc(cc([N+](=O)[O-])c2-c3c1cc(cc3[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G22 compound treatment 725768.0 244000.0 0.5 701454.0 220000.0 0.48 0.6937 0.9996 1549697 ChemDiv1_025146 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccc(Cl)c(Cl)c3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G23 mock treatment 716649.0 235000.0 0.49 703931.0 223000.0 0.48 0.6842 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 G24 mock treatment 215737.0 -266000.0 -0.55 252409.0 -229000.0 -0.49 -0.738 -0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H01 compound treatment 541018.0 59300.0 0.12 633662.0 153000.0 0.33 0.3203 0.9088 1316312 ChemDiv1_025147 Cc1ccccc1C2(CC2C(=O)Nc3ccc(Br)cc3)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H02 compound treatment 654341.0 173000.0 0.36 624280.0 143000.0 0.31 0.4714 0.9976 1188952 ChemDiv1_025148 CC1(C)OC(=O)N(CCC(=O)O)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H03 compound treatment 709307.0 228000.0 0.47 691002.0 210000.0 0.45 0.6537 0.9999 1527404 ChemDiv1_025149 Cc1ccccc1C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H04 compound treatment 657592.0 176000.0 0.36 664167.0 183000.0 0.4 0.5372 0.999 1981490 ChemDiv1_025150 Cc1ccc(Cl)cc1/N=C/2\NC(=S)N(C3CCCCC3)C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H05 compound treatment 873587.0 392000.0 0.81 871322.0 390000.0 0.84 1.1695 0.9998 1672002 ChemDiv1_025151 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(O)cc3)sc2=C(C#N)C1c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H06 compound treatment 757112.0 275000.0 0.57 696232.0 215000.0 0.47 0.7315 0.9951 1359781 ChemDiv1_025152 CC(C)c1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H07 compound treatment 967954.0 486000.0 1.0 821103.0 340000.0 0.74 1.2304 0.9884 1981491 ChemDiv1_025153 Cc1ccc2N3[C@@H]([C@@H](c4ccc(Br)cc4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H08 compound treatment 730475.0 249000.0 0.51 704151.0 223000.0 0.48 0.7047 0.9995 1981492 ChemDiv1_025154 CC1(CCN2CCC(C)(c3ccccc3)c4cc(cc1c24)[N+](=O)[O-])c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H09 compound treatment 756234.0 275000.0 0.57 706735.0 226000.0 0.49 0.7463 0.9973 1515266 ChemDiv1_025155 C(Oc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H10 compound treatment 735885.0 254000.0 0.52 730836.0 250000.0 0.54 0.7535 0.9999 1981493 ChemDiv1_025156 Cc1cccc(/N=C/2\NC(=S)N(CC#N)C32CCCC3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H11 compound treatment 743612.0 262000.0 0.54 719153.0 238000.0 0.52 0.7469 0.9997 1981494 ChemDiv1_025157 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)c2ccc3C4C=CCC4CN5CC6CC=CC6c2c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H12 compound treatment 848448.0 367000.0 0.76 778676.0 298000.0 0.64 0.991 0.9968 1733392 ChemDiv1_025158 NC1=C(C#N)C2=CCCCC2C(c3ccc(F)cc3F)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H13 compound treatment 764410.0 283000.0 0.58 702082.0 221000.0 0.48 0.7511 0.9951 1981495 ChemDiv1_025159 CCOC(=O)C1=NN(c2ccc(OC)cc2)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H14 compound treatment 747159.0 265000.0 0.55 751798.0 271000.0 0.59 0.802 0.9994 1981496 ChemDiv1_025160 COCON1C(N(CC1=O)C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H15 compound treatment 785074.0 303000.0 0.63 731716.0 251000.0 0.54 0.8266 0.9975 1981497 ChemDiv1_025161 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H16 compound treatment 730000.0 248000.0 0.51 692416.0 211000.0 0.46 0.6861 0.9984 1981498 ChemDiv1_025162 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3C)C42CCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H17 compound treatment 744910.0 263000.0 0.54 754307.0 273000.0 0.59 0.8026 0.9991 1981499 ChemDiv1_025163 CC(C)N1C(=S)N/C(=N\c2cc(Cl)ccc2C)/C31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H18 compound treatment 756868.0 275000.0 0.57 704794.0 224000.0 0.48 0.7443 0.9969 1981500 ChemDiv1_025164 Cc1cccc(/N=C/2\NC(=S)N(c3ccc(I)cc3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H19 compound treatment 751254.0 270000.0 0.56 698383.0 217000.0 0.47 0.7262 0.9965 1981501 ChemDiv1_025165 Cc1cccc(c1)n2nnnc2C3(CCCCC3)/N=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H20 compound treatment 740923.0 259000.0 0.54 703243.0 222000.0 0.48 0.7186 0.9986 1981502 ChemDiv1_025166 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccccc2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H21 compound treatment 768592.0 287000.0 0.59 745554.0 265000.0 0.57 0.8237 0.9999 1165632 ChemDiv1_025167 Cc1cccc(c1)C2(CC2C(=O)Nc3ccc(Cl)c(Cl)c3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H22 compound treatment 828727.0 347000.0 0.72 802165.0 321000.0 0.7 0.9982 0.9999 1228658 ChemDiv1_025168 COc1cc(cc(OC)c1OC)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H23 mock treatment 723922.0 242000.0 0.5 702138.0 221000.0 0.48 0.6921 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 H24 mock treatment 239403.0 -242000.0 -0.5 249843.0 -231000.0 -0.5 -0.7074 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I01 compound treatment 619086.0 137000.0 0.28 581429.0 100000.0 0.22 0.3543 0.9914 1981503 ChemDiv1_025169 [O-][N+](=O)c1ccc(cc1)c2nc([nH]c2c3ccc(Oc4ccc(cc4)c5nc([nH]c5c6ccc(cc6)[N+](=O)[O-])c7ccc(Br)cc7)cc3)c8ccc(Br)cc8 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I02 compound treatment 636710.0 155000.0 0.32 615481.0 135000.0 0.29 0.4322 0.9989 1981504 ChemDiv1_025170 [O-][N+](=O)c1ccc-2c(c1)C(=C(C#N)C#N)c3cccc([N+](=O)[O-])c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I03 compound treatment 709532.0 228000.0 0.47 729382.0 248000.0 0.54 0.7128 0.9978 1340685 ChemDiv1_025171 Cc1ccc(cc1)C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I04 compound treatment 677003.0 195000.0 0.4 668723.0 188000.0 0.41 0.5725 1.0 1981505 ChemDiv1_025172 [O-][N+](=O)c1cccc(c1)[C@H]2CC(=CC(=O)[C@@H]2n3nnc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I05 compound treatment 720044.0 238000.0 0.49 694698.0 214000.0 0.46 0.6751 0.9995 1981506 ChemDiv1_025173 C1Oc2ccccc2C3OC(c4ccccc4)(c5ccccc5)c6ccccc6N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I06 compound treatment 737718.0 256000.0 0.53 676221.0 195000.0 0.42 0.6726 0.9939 1276130 ChemDiv1_025174 N#Cc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I07 compound treatment 899647.0 418000.0 0.86 821825.0 341000.0 0.74 1.1318 0.997 1981507 ChemDiv1_025175 COc1ccc(/N=C\c2ccc(O)c3C(C(=C(N)Oc23)C#N)c4cccc(c4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I08 compound treatment 721671.0 240000.0 0.5 709113.0 228000.0 0.49 0.6995 1.0 1227634 ChemDiv1_025176 CC(C)Oc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I09 compound treatment 2072209.0 1590000.0 3.28 2466811.0 1990000.0 4.3 5.3609 0.9912 1981508 ChemDiv1_025177 CC1(C)SC(=S)N(/N=C/C=C/c2ccc(o2)[N+](=O)[O-])C1N(O)C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I10 compound treatment 725926.0 244000.0 0.5 719110.0 238000.0 0.52 0.721 0.9999 1981509 ChemDiv1_025178 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccc(cc2)[N+](=O)[O-])c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I11 compound treatment 673765.0 192000.0 0.4 641753.0 161000.0 0.35 0.5265 0.9979 1981510 ChemDiv1_025179 Cc1cc(C)c(/N=C/2\c3ccccc3-c4ncccc24)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I12 compound treatment 692476.0 211000.0 0.44 674194.0 193000.0 0.42 0.6034 0.9998 1585950 ChemDiv1_025180 COC(=O)c1ccc(cc1)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I13 compound treatment 696362.0 215000.0 0.44 713307.0 232000.0 0.5 0.669 0.998 1981511 ChemDiv1_025181 CC(=O)c1cccc(NC(=O)C2CC2c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I14 compound treatment 671688.0 190000.0 0.39 641407.0 160000.0 0.35 0.5229 0.9982 1437382 ChemDiv1_025182 CCCOc1ccc(cc1)C2(CNC(=O)Cc3ccc(OC)c(OC)c3)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I15 compound treatment 772839.0 291000.0 0.6 753683.0 273000.0 0.59 0.8424 1.0 1383602 ChemDiv1_025183 COc1ccc(cc1OC)C2(CNC(=O)CC#N)CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I16 compound treatment 748940.0 267000.0 0.55 737707.0 257000.0 0.56 0.7831 1.0 1526495 ChemDiv1_025184 CCOC(=O)COc1ccc(cc1OC)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I17 compound treatment 788563.0 307000.0 0.63 726692.0 246000.0 0.53 0.824 0.9962 1394623 ChemDiv1_025185 CCOC(=O)c1cc2C(=O)c3ccccc3-c2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I18 compound treatment 712001.0 230000.0 0.48 721562.0 241000.0 0.52 0.7044 0.999 1981512 ChemDiv1_025186 [O-][N+](=O)c1nnn(n1)[C@@H]2[C@H](CC(=CC2=O)c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I19 compound treatment 737301.0 256000.0 0.53 714653.0 234000.0 0.51 0.7308 0.9998 1981513 ChemDiv1_025187 Cc1ccc-2c(c1)/C(=N/c3ccccc3)/c4cc5cccc(C)c5nc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I20 compound treatment 702434.0 221000.0 0.46 712316.0 231000.0 0.5 0.6763 0.9989 1981514 ChemDiv1_025188 CCOC(=O)c1cc2/C(=N\c3ccc-4c(Cc5ccccc54)c3)/c6ccccc6-c2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I21 compound treatment 728282.0 247000.0 0.51 719014.0 238000.0 0.52 0.7243 1.0 1981515 ChemDiv1_025189 CCO/C=C/1\c2cc(ccc2-c3c1cc(cc3[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I22 compound treatment 689590.0 208000.0 0.43 687747.0 207000.0 0.45 0.62 0.9998 1981516 ChemDiv1_025190 CC(C)C(=O)OC1CC(OC1CO)n2cc(C)c(=O)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I23 mock treatment 717422.0 236000.0 0.49 689546.0 209000.0 0.45 0.6633 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 I24 mock treatment 212313.0 -269000.0 -0.56 236492.0 -244000.0 -0.53 -0.7673 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J01 compound treatment 645367.0 164000.0 0.34 601709.0 121000.0 0.26 0.4237 0.9919 1981517 ChemDiv1_025191 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3cc(C)ccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J02 compound treatment 681541.0 200000.0 0.41 635164.0 154000.0 0.33 0.5277 0.9945 1499369 ChemDiv1_025192 CCOC(=O)c1nnn(c1CN2CCN(Cc3ccccc3)CC2)c4nonc4N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J03 compound treatment 739691.0 258000.0 0.53 736475.0 256000.0 0.55 0.7677 0.9998 1981518 ChemDiv1_025193 COc1ccc(Br)cc1C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4cc(Br)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J04 compound treatment 682620.0 201000.0 0.41 667982.0 187000.0 0.4 0.5795 0.9999 1223491 ChemDiv1_025194 Cc1cccc2-c3c(ssc3=Nc4cccc(Cl)c4)C(C)(C)Nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J05 compound treatment 821454.0 340000.0 0.7 840864.0 360000.0 0.78 1.0468 0.9986 1981519 ChemDiv1_025195 Fc1ccc(cc1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J06 compound treatment 712695.0 231000.0 0.48 705928.0 225000.0 0.49 0.6815 0.9999 1981520 ChemDiv1_025196 CCCCCCOc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J07 compound treatment 871110.0 389000.0 0.8 925183.0 444000.0 0.96 1.2483 0.996 1981521 ChemDiv1_025197 NC1=C(C#N)C(c2cccc(c2)[N+](=O)[O-])c3c(O)ccc(/C=N\c4ccccc4)c3O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J08 compound treatment 749660.0 268000.0 0.55 725114.0 244000.0 0.53 0.7648 0.9997 1600738 ChemDiv1_025198 OC(=O)c1ccc2noc(c3ccccc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J09 compound treatment 734898.0 253000.0 0.52 742691.0 262000.0 0.57 0.7702 0.9992 1230912 ChemDiv1_025199 CCOC(=O)c1nnn(c1CN2CCCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J10 compound treatment 751682.0 270000.0 0.56 716138.0 235000.0 0.51 0.754 0.999 1981522 ChemDiv1_025200 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCCC3)N1c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J11 compound treatment 796747.0 315000.0 0.65 830037.0 349000.0 0.76 0.9941 0.9972 1118284 ChemDiv1_025201 Brc1ccc(cc1)C(=O)COC(=O)c2ccc3C4C=CCC4CN5CC6CC=CC6c2c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J12 compound treatment 882557.0 401000.0 0.83 736755.0 256000.0 0.55 0.9766 0.9809 1338732 ChemDiv1_025202 COC(=O)C1=C(N)n2c(=O)c(=Cc3ccccc3)sc2=C(C#N)C1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J13 compound treatment 726129.0 244000.0 0.5 725997.0 245000.0 0.53 0.7318 0.9997 1981523 ChemDiv1_025203 CC(=O)C1=NN(c2ccccc2Cl)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J14 compound treatment 739969.0 258000.0 0.53 734882.0 254000.0 0.55 0.7656 0.9999 1461625 ChemDiv1_025204 COc1cc(ccc1OC(=O)C)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J15 compound treatment 798329.0 317000.0 0.65 772136.0 291000.0 0.63 0.9078 0.9998 1981524 ChemDiv1_025205 CNC(=O)N(O)C1N(/N=C/c2ccccc2)C(=S)SC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J16 compound treatment 773614.0 292000.0 0.6 722572.0 242000.0 0.52 0.7959 0.9975 1981525 ChemDiv1_025206 Cc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(C)c3)/C42CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J17 compound treatment 739193.0 258000.0 0.53 615516.0 135000.0 0.29 0.5818 0.9599 1981526 ChemDiv1_025207 Cc1ccc(N/C(=N\OCc2ccccc2[N+](=O)[O-])/c3nonc3N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J18 compound treatment 759125.0 277000.0 0.57 715225.0 234000.0 0.51 0.7635 0.9982 1981527 ChemDiv1_025208 CCOC(=O)c1cc2/C(=N\c3cccc4ccccc34)/c5ccccc5-c2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J19 compound treatment 740691.0 259000.0 0.53 705769.0 225000.0 0.49 0.7221 0.9989 1981528 ChemDiv1_025209 COc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(C)c3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J20 compound treatment 668043.0 186000.0 0.38 707631.0 227000.0 0.49 0.6189 0.9928 1981529 ChemDiv1_025210 C(=C/c1nc2ccccc2[nH]1)\c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J21 compound treatment 758480.0 277000.0 0.57 740435.0 259000.0 0.56 0.8012 1.0 1981530 ChemDiv1_025211 Cc1cc(ccc1[N+](=O)[O-])c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J22 compound treatment 753989.0 272000.0 0.56 771530.0 291000.0 0.63 0.8422 0.9984 1981531 ChemDiv1_025212 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccc(OC)c(OC)c3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J23 mock treatment 727909.0 246000.0 0.51 726270.0 245000.0 0.53 0.7349 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 J24 mock treatment 233623.0 -248000.0 -0.51 258210.0 -223000.0 -0.48 -0.703 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K01 compound treatment 653889.0 172000.0 0.36 575099.0 94100.0 0.2 0.3954 0.9651 1981532 ChemDiv1_025213 Cc1ccc(NC=C2C(=O)N(C(=S)N(C2=O)c3ccccc3)c4ccccc4)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K02 compound treatment 637569.0 156000.0 0.32 626594.0 146000.0 0.32 0.4504 0.9999 1981533 ChemDiv1_025214 CCCCCOc1ccc(/C=C/2\c3cc(ccc3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K03 compound treatment 689935.0 208000.0 0.43 688798.0 208000.0 0.45 0.6221 0.9997 1981534 ChemDiv1_025215 CC1(C)SC(=S)N(/N=C/c2ccco2)C1N(O)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K04 compound treatment 671459.0 190000.0 0.39 682475.0 202000.0 0.44 0.5854 0.9986 1981535 ChemDiv1_025216 O=C1C=C(C[C@@H]([C@H]1n2nnc3ccccc23)c4cccs4)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K05 compound treatment 712437.0 231000.0 0.48 700248.0 219000.0 0.47 0.6724 1.0 1981536 ChemDiv1_025217 CN(C)c1ccc(cc1)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K06 compound treatment 654709.0 173000.0 0.36 674010.0 193000.0 0.42 0.548 0.997 1138833 ChemDiv1_025218 Clc1cccc(c1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K07 compound treatment 789842.0 308000.0 0.64 784480.0 304000.0 0.66 0.9143 0.9999 1504962 ChemDiv1_025219 CC1CC=C2C(C1)C(c3cccc(Cl)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K08 compound treatment 861152.0 379000.0 0.78 704486.0 224000.0 0.48 0.896 0.9732 1981537 ChemDiv1_025220 COc1ccc(OC2OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C2OC(=O)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K09 compound treatment 757813.0 276000.0 0.57 712017.0 231000.0 0.5 0.7567 0.9979 1981538 ChemDiv1_025221 CC1(C)SC(=S)N(/N=C/c2ccc(Cl)cc2)C1N(O)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K10 compound treatment 689275.0 208000.0 0.43 690059.0 209000.0 0.45 0.623 0.9996 1981539 ChemDiv1_025222 CCc1ccc(cc1)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K11 compound treatment 682992.0 201000.0 0.42 677321.0 196000.0 0.43 0.5944 0.9999 1981540 ChemDiv1_025223 Cc1ccc-2c(c1)/C(=N\c3c(C)cc(C)cc3C)/c4cccnc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K12 compound treatment 699776.0 218000.0 0.45 692331.0 211000.0 0.46 0.6418 1.0 1981541 ChemDiv1_025224 O=C(NC1=C(C#N)C2(CCCC2)Cc3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K13 compound treatment 746084.0 264000.0 0.55 713022.0 232000.0 0.5 0.7411 0.9991 1981542 ChemDiv1_025225 CCS/C=C(\NC(=O)c1ccccc1)/[P+](c2ccccc2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K14 compound treatment 724852.0 243000.0 0.5 713807.0 233000.0 0.5 0.7113 1.0 1981543 ChemDiv1_025226 CC(=O)OCC1OC(Oc2ccc(C(=O)OCCCN3CCOCC3)c(O)c2)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K15 compound treatment 730686.0 249000.0 0.51 748898.0 268000.0 0.58 0.7735 0.9982 1981544 ChemDiv1_025227 CSc1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)[N+](=O)[O-])c4ccc(Oc5ccc(cc5)c6[nH]c(nc6c7ccc(cc7)[N+](=O)[O-])c8ccc(SC)cc8)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K16 compound treatment 680521.0 199000.0 0.41 701679.0 221000.0 0.48 0.628 0.9971 1981545 ChemDiv1_025228 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc([N+](=O)[O-])c(cc4N5CCCCC5)N6CCCCC6)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K17 compound treatment 708660.0 227000.0 0.47 727930.0 247000.0 0.53 0.7093 0.9978 1981546 ChemDiv1_025229 Cc1cc2/C(=N/c3ccccc3)/c4cc5ccccc5nc4-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K18 compound treatment 708307.0 227000.0 0.47 674874.0 194000.0 0.42 0.6276 0.9985 1981547 ChemDiv1_025230 [O-][N+](=O)c1nnn(n1)[C@@H]2[C@H](CC(=CC2=O)/C=C/c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K19 compound treatment 733195.0 252000.0 0.52 736159.0 255000.0 0.55 0.7577 0.9995 1981548 ChemDiv1_025231 Cc1ccc2/C(=C/c3ccc(Br)cc3)/c4cc5ccccc5nc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K20 compound treatment 708405.0 227000.0 0.47 699619.0 219000.0 0.47 0.6656 1.0 1981549 ChemDiv1_025232 Cc1ccc(/N=C\2/c3ccccc3-c4nc5ccccc5cc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K21 compound treatment 658758.0 177000.0 0.37 626948.0 146000.0 0.32 0.4819 0.9974 1981550 ChemDiv1_025233 CCOc1ccc(C=C2c3cc(cc([N+](=O)[O-])c3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K22 compound treatment 723846.0 242000.0 0.5 706455.0 225000.0 0.49 0.6986 0.9999 1981551 ChemDiv1_025234 COc1ccc(cc1Br)C(c2c(C)n(C)n(c3ccccc3)c2=O)c4c(C)n(C)n(c5ccccc5)c4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K23 mock treatment 735519.0 254000.0 0.52 713939.0 233000.0 0.5 0.7271 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 K24 mock treatment 245016.0 -237000.0 -0.49 244073.0 -237000.0 -0.51 -0.708 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L01 compound treatment 611701.0 130000.0 0.27 630859.0 150000.0 0.32 0.4192 0.9956 1777542 ChemDiv1_025235 CC1(C2C(C(=O)N(C2=O)c3cccc(c3)[N+](=O)[O-])C4(C)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L02 compound treatment 657045.0 175000.0 0.36 651716.0 171000.0 0.37 0.5173 0.9999 1243048 ChemDiv1_025236 CCOC(=O)C1CCN(Cc2c(nnn2c3nonc3N)C(=O)OCC)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L03 compound treatment 719834.0 238000.0 0.49 719845.0 239000.0 0.52 0.7132 0.9997 1298630 ChemDiv1_025237 NC1=C(C#N)C(C(=c2sc(=Cc3cccc(Cl)c3Cl)c(=O)n12)C#N)c4cccc(Cl)c4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L04 compound treatment 666852.0 185000.0 0.38 650982.0 170000.0 0.37 0.5305 0.9998 1981552 ChemDiv1_025238 Cc1ccccc1N/C(=N\OCc2ccc(Cl)cc2Cl)/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L05 compound treatment 797603.0 316000.0 0.65 784468.0 304000.0 0.66 0.9257 1.0 1981553 ChemDiv1_025239 Fc1ccc(cc1)C(=O)[C@H]2[C@H](c3cccc(F)c3)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L06 compound treatment 687194.0 206000.0 0.42 667170.0 186000.0 0.4 0.585 0.9997 2408 ChemDiv1_025240 NCCC(O)(P(=O)(O)O)P(=O)(O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L07 compound treatment 705315.0 224000.0 0.46 721271.0 240000.0 0.52 0.6942 0.9982 1426906 ChemDiv1_025241 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(cc3)C(C)C)sc2=C(C#N)C1c4ccc(cc4)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L08 compound treatment 713665.0 232000.0 0.48 736367.0 255000.0 0.55 0.7295 0.9974 1981554 ChemDiv1_025242 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cc(C)ccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L09 compound treatment 743247.0 262000.0 0.54 704794.0 224000.0 0.48 0.7244 0.9985 1568314 ChemDiv1_025243 CC1(C)OC(=O)N(CCO)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L10 compound treatment 740730.0 259000.0 0.53 696910.0 216000.0 0.47 0.7086 0.9977 1131330 ChemDiv1_025244 Cc1cccc(c1)C2(CC2C(=O)Nc3ccc(C#N)cc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L11 compound treatment 825473.0 344000.0 0.71 843237.0 362000.0 0.78 1.0563 0.9988 1393689 ChemDiv1_025245 Clc1ccc(cc1)C(=O)COC(=O)c2ccc3C4C=CCC4CN5CC6CC=CC6c2c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L12 compound treatment 746252.0 265000.0 0.55 707611.0 227000.0 0.49 0.7331 0.9986 1312730 ChemDiv1_025246 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3cccnc3)sc2=C(C#N)C1c4cccnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L13 compound treatment 733987.0 252000.0 0.52 714690.0 234000.0 0.51 0.726 0.9999 1981555 ChemDiv1_025247 Clc1ccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L14 compound treatment 749794.0 268000.0 0.55 727634.0 247000.0 0.53 0.7689 0.9998 1981556 ChemDiv1_025248 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccc(Br)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L15 compound treatment 783233.0 302000.0 0.62 760369.0 279000.0 0.6 0.8678 0.9999 1981557 ChemDiv1_025249 CC1(C)SC(=S)N(/N=C/c2ccccc2)C1N(O)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L16 compound treatment 736372.0 255000.0 0.53 715077.0 234000.0 0.51 0.7301 0.9998 1981558 ChemDiv1_025250 Cc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(C)c3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L17 compound treatment 769917.0 288000.0 0.6 770588.0 290000.0 0.63 0.864 0.9997 1414275 ChemDiv1_025251 COc1ccc(cc1)c2c3C(=O)c4ccccc4C(=O)c3c(c5ccccc5)n2c6ccc(N)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L18 compound treatment 724041.0 242000.0 0.5 714415.0 233000.0 0.51 0.7111 1.0 1981559 ChemDiv1_025252 CCCCNC(=O)N(O)C1N(CCc2ccc(OC)c(OC)c2)C(=S)SC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L19 compound treatment 750132.0 268000.0 0.55 699219.0 218000.0 0.47 0.7259 0.9968 1981560 ChemDiv1_025253 Cc1cccc(/N=C/2\NC(=S)N(CC#N)C32CCCCC3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L20 compound treatment 725560.0 244000.0 0.5 733629.0 253000.0 0.55 0.7427 0.9991 1553970 ChemDiv1_025254 CCOc1ccc2NC(C)(C)c3ssc(=Nc4cccc(F)c4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L21 compound treatment 744634.0 263000.0 0.54 767389.0 286000.0 0.62 0.8222 0.9978 1781329 ChemDiv1_025255 OC1=C(C(N(C1=O)c2nccs2)c3ccc(cc3)[N+](=O)[O-])C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L22 compound treatment 701291.0 220000.0 0.45 721746.0 241000.0 0.52 0.6891 0.9976 1249763 ChemDiv1_025256 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L23 mock treatment 757784.0 276000.0 0.57 724373.0 243000.0 0.53 0.7756 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 L24 mock treatment 224407.0 -257000.0 -0.53 226523.0 -254000.0 -0.55 -0.7649 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M01 compound treatment 610346.0 129000.0 0.27 597824.0 117000.0 0.25 0.3667 0.9997 1981561 ChemDiv1_025257 C=CCNC=C1C(=O)N(C(=S)N(C1=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M02 compound treatment 621554.0 140000.0 0.29 627654.0 147000.0 0.32 0.4287 0.9989 1981562 ChemDiv1_025258 CCCCCCOc1ccc(/C=C/2\c3cc(ccc3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M03 compound treatment 691087.0 209000.0 0.43 671217.0 190000.0 0.41 0.5968 0.9997 1981563 ChemDiv1_025259 CC1(C)SC(=S)N(/N=C/c2ccco2)C1N(O)C(=O)Nc3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M04 compound treatment 644569.0 163000.0 0.34 667941.0 187000.0 0.4 0.5239 0.9958 1981564 ChemDiv1_025260 O=C1C=C(C[C@@H]([C@H]1n2nnc3ccccc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M05 compound treatment 941823.0 460000.0 0.95 629246.0 148000.0 0.32 0.8986 0.8963 1981565 ChemDiv1_025261 CC1=Nc2ccccc2C(O1)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M06 compound treatment 686949.0 205000.0 0.42 676291.0 195000.0 0.42 0.5986 1.0 1483661 ChemDiv1_025262 Cc1cccc(c1)C2(CC2C(=O)Nc3c(C)cc(C)cc3C)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M07 compound treatment 878804.0 397000.0 0.82 792800.0 312000.0 0.67 1.0569 0.9953 1597488 ChemDiv1_025263 CCOC(=O)N1CC=C2C(C1)C(c3cccc(Cl)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M08 compound treatment 705763.0 224000.0 0.46 682476.0 202000.0 0.44 0.6355 0.9996 1981566 ChemDiv1_025264 OCC1OC(Oc2ccc(Br)cc2)C(O)C(O)C1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M09 compound treatment 721756.0 240000.0 0.5 706864.0 226000.0 0.49 0.6962 1.0 1981567 ChemDiv1_025265 CCCCNC(=O)N(O)C1N(/N=C/c2ccco2)C(=S)SC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M10 compound treatment 678345.0 197000.0 0.41 662421.0 181000.0 0.39 0.5648 0.9999 1981568 ChemDiv1_025266 Cc1ccc(cc1)C(=O)O/N=C(\Nc2cc(C)ccc2C)/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M11 compound treatment 736884.0 255000.0 0.53 700812.0 220000.0 0.48 0.709 0.9987 1490325 ChemDiv1_025267 Cc1cc2Cc3cc4ccccc4nc3-c2c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M12 compound treatment 703931.0 222000.0 0.46 699953.0 219000.0 0.47 0.6596 0.9999 1981569 ChemDiv1_025268 O=C(NC(=S)NC1=C(C#N)C2(CCCCC2)Cc3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M13 compound treatment 725834.0 244000.0 0.5 688356.0 207000.0 0.45 0.6738 0.9983 1981570 ChemDiv1_025269 Cl/C(=C(/NC=O)\[P+](c1ccccc1)(c2ccccc2)c3ccccc3)/SCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M14 compound treatment 727338.0 246000.0 0.51 720184.0 239000.0 0.52 0.7247 0.9999 1981571 ChemDiv1_025270 CC(=O)OCC1OC(Oc2ccc(cc2OC3OC(COC(=O)C)C(OC(=O)C)C(OC(=O)C)C3OC(=O)C)C(=O)O)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M15 compound treatment 689876.0 208000.0 0.43 713086.0 232000.0 0.5 0.6592 0.997 1981572 ChemDiv1_025271 [O-][N+](=O)c1ccccc1S(=O)(=O)Oc2ccccc2/C=N/NC(=O)C3(CCC3)C(=O)N\N=C/c4ccccc4OS(=O)(=O)c5ccccc5[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M16 compound treatment 665959.0 184000.0 0.38 699274.0 218000.0 0.47 0.6031 0.9942 1870288 ChemDiv1_025272 [O-][N+](=O)c1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M17 compound treatment 737059.0 255000.0 0.53 728430.0 247000.0 0.54 0.7515 1.0 1379622 ChemDiv1_025273 Cc1ccc-2c(c1)C(=O)c3cc4ccccc4nc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M18 compound treatment 724221.0 243000.0 0.5 695294.0 214000.0 0.46 0.6821 0.9993 1981573 ChemDiv1_025274 [O-][N+](=O)c1cn(cn1)[C@@H]2[C@H](CC(=CC2=O)c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M19 compound treatment 743086.0 261000.0 0.54 737966.0 257000.0 0.56 0.7749 0.9999 1981574 ChemDiv1_025275 COc1ccc(/C=C\2/c3cc(C)ccc3-c4nc5ccccc5cc24)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M20 compound treatment 671566.0 190000.0 0.39 688189.0 207000.0 0.45 0.5943 0.9977 1981575 ChemDiv1_025276 COc1ccc(/C=C\2/c3ccccc3-c4nc5ccccc5cc24)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M21 compound treatment 666336.0 185000.0 0.38 673356.0 192000.0 0.42 0.564 0.999 1981576 ChemDiv1_025277 CCCCCOc1ccc(C=C2c3cc(cc([N+](=O)[O-])c3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M22 compound treatment 706011.0 224000.0 0.46 699057.0 218000.0 0.47 0.6612 1.0 1456736 ChemDiv1_025278 OC1=C2C(Sc3ccccc3N=C2c4ccccc14)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M23 mock treatment 709286.0 228000.0 0.47 684489.0 204000.0 0.44 0.6437 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 M24 mock treatment 353890.0 -128000.0 -0.26 384268.0 -96700.0 -0.21 -0.3345 -0.9934 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N01 compound treatment 605901.0 124000.0 0.26 591757.0 111000.0 0.24 0.3509 0.9994 1981577 ChemDiv1_025279 COc1ccc(CO/N=C(\Nc2ccc(C)cc2)/c3nonc3N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N02 compound treatment 669465.0 188000.0 0.39 649414.0 168000.0 0.36 0.5319 0.9995 1172113 ChemDiv1_025280 Cc1cccc(c1)C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N03 compound treatment 708463.0 227000.0 0.47 730807.0 250000.0 0.54 0.7134 0.9974 1401797 ChemDiv1_025281 NC1=C(C#N)C(C(=c2sc(=Cc3cc(Br)ccc3F)c(=O)n12)C#N)c4cc(Br)ccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N04 compound treatment 665849.0 184000.0 0.38 665348.0 184000.0 0.4 0.551 0.9997 1981578 ChemDiv1_025282 Clc1ccc(N=c2scc(c3ccccc3)n2c4ccccc4)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N05 compound treatment 793485.0 312000.0 0.64 769862.0 289000.0 0.63 0.8973 0.9999 1981579 ChemDiv1_025283 O=C([C@H]1[C@H](c2ccsc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N06 compound treatment 680205.0 199000.0 0.41 672437.0 191000.0 0.41 0.5828 1.0 1164136 ChemDiv1_025284 CN(C)c1ccc(cc1)C2N(CCN2c3cccc(C)c3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N07 compound treatment 715639.0 234000.0 0.48 702133.0 221000.0 0.48 0.68 1.0 1571956 ChemDiv1_025285 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(F)cc3)sc2=C(C#N)C1c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N08 compound treatment 714993.0 233000.0 0.48 705836.0 225000.0 0.49 0.6847 1.0 1981580 ChemDiv1_025286 CCCS(=O)(=O)c1c(C(=O)N/N=C/C(C)C)n2cccc(C)c2c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N09 compound treatment 735217.0 254000.0 0.52 753171.0 272000.0 0.59 0.7867 0.9983 1981581 ChemDiv1_025287 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccccc2)c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N10 compound treatment 687431.0 206000.0 0.42 695038.0 214000.0 0.46 0.628 0.9991 1458733 ChemDiv1_025288 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccccc3F)sc2=C(C#N)C1c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N11 compound treatment 768103.0 286000.0 0.59 712122.0 231000.0 0.5 0.7719 0.9965 1981582 ChemDiv1_025289 CC1(C)C2CCC1(C)C(=O)N(C2=O)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N12 compound treatment 748870.0 267000.0 0.55 718548.0 238000.0 0.51 0.7536 0.9994 1981583 ChemDiv1_025290 CC(C)(C)C(=O)[C@H]1[C@H](c2ccc(Br)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N13 compound treatment 716872.0 235000.0 0.49 736728.0 256000.0 0.55 0.7347 0.9979 1657388 ChemDiv1_025291 COc1ccc(cc1)c2oc(NC(=O)C)c(C#N)c2c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N14 compound treatment 706058.0 224000.0 0.46 708697.0 228000.0 0.49 0.6761 0.9995 1981584 ChemDiv1_025292 Cc1cccc(/N=C/2\NC(=S)N(c3ccc(Br)cc3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N15 compound treatment 746852.0 265000.0 0.55 748765.0 268000.0 0.58 0.7969 0.9996 1518255 ChemDiv1_025293 Clc1ccc(OC(=O)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N16 compound treatment 699655.0 218000.0 0.45 697359.0 216000.0 0.47 0.6494 0.9998 1981585 ChemDiv1_025294 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N17 compound treatment 748277.0 267000.0 0.55 731556.0 251000.0 0.54 0.7727 1.0 1981586 ChemDiv1_025295 CC(C)c1ccc(cc1)n2c(c3C(=O)c4ccccc4C(=O)c3c2c5ccc(Cl)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N18 compound treatment 718521.0 237000.0 0.49 700085.0 219000.0 0.47 0.6811 0.9999 1336760 ChemDiv1_025296 COc1ccc(CCN2C(N(O)C(=O)NC3CCCCC3)C(C)(C)SC2=S)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N19 compound treatment 769334.0 288000.0 0.59 745543.0 265000.0 0.57 0.8248 0.9998 1981587 ChemDiv1_025297 CCOC(=O)c1ccc(cc1)N2C(=S)N/C(=N\c3cccc(C)c3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N20 compound treatment 742925.0 261000.0 0.54 717341.0 236000.0 0.51 0.7431 0.9997 1240625 ChemDiv1_025298 CCOc1ccc2NC(C)(C)c3ssc(=Nc4cccc(Cl)c4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N21 compound treatment 761635.0 280000.0 0.58 732321.0 251000.0 0.54 0.7933 0.9995 1364339 ChemDiv1_025299 Cc1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N22 compound treatment 735246.0 254000.0 0.52 718955.0 238000.0 0.52 0.7344 1.0 1981588 ChemDiv1_025300 CC(C)c1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(cc5)[N+](=O)[O-])C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N23 mock treatment 715612.0 234000.0 0.48 686032.0 205000.0 0.44 0.6553 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 N24 mock treatment 240785.0 -241000.0 -0.5 376121.0 -105000.0 -0.23 -0.5121 -0.9368 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O01 compound treatment 616869.0 135000.0 0.28 585202.0 104000.0 0.23 0.3569 0.9944 1981589 ChemDiv1_025301 COc1ccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O02 compound treatment 628283.0 147000.0 0.3 623763.0 143000.0 0.31 0.4325 0.9999 1981590 ChemDiv1_025302 CCCCCCCCOc1ccc(/C=C/2\c3cc(ccc3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O03 compound treatment 667054.0 185000.0 0.38 652253.0 171000.0 0.37 0.5327 0.9999 1981591 ChemDiv1_025303 CNC(=O)N(O)C1N(/N=C/c2ccco2)C(=S)SC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O04 compound treatment 677693.0 196000.0 0.4 657887.0 177000.0 0.38 0.5569 0.9996 1981592 ChemDiv1_025304 O=C1C=C(C[C@@H]([C@H]1n2nnc3ccccc23)c4cccs4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O05 compound treatment 674307.0 193000.0 0.4 657757.0 177000.0 0.38 0.5518 0.9998 1916846 ChemDiv1_025305 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc(Br)ccc4O)ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O06 compound treatment 660806.0 179000.0 0.37 632823.0 152000.0 0.33 0.4939 0.9983 1981593 ChemDiv1_025306 COc1ccc(cc1C(c2c(C)n(C)n(c3ccccc3)c2=O)c4c(C)n(C)n(c5ccccc5)c4=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O07 compound treatment 890177.0 408000.0 0.84 817750.0 337000.0 0.73 1.1117 0.9974 1320077 ChemDiv1_025307 CC(C)(C)OC(=O)N1CC=C2C(C1)C(c3cccc(Cl)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O08 compound treatment 705846.0 224000.0 0.46 679462.0 199000.0 0.43 0.631 0.9993 1981594 ChemDiv1_025308 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O09 compound treatment 966430.0 485000.0 1.0 690024.0 209000.0 0.45 1.0275 0.9356 1981595 ChemDiv1_025309 CC1(C)SC(=S)N(/N=C/c2ccco2)C1N(O)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O10 compound treatment 679559.0 198000.0 0.41 655514.0 175000.0 0.38 0.556 0.9992 1981596 ChemDiv1_025310 COc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6)c7ccccc47)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O11 compound treatment 693396.0 212000.0 0.44 677393.0 196000.0 0.43 0.6097 0.9999 1344742 ChemDiv1_025311 Cc1cc2C(=O)c3cc4ccccc4nc3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O12 compound treatment 666677.0 185000.0 0.38 579478.0 98500.0 0.21 0.4208 0.9621 1981597 ChemDiv1_025312 O=c1c2c(-c3ccccc3CC42CCCCC4)n5cnnc5n1c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O13 compound treatment 710383.0 229000.0 0.47 682803.0 202000.0 0.44 0.6427 0.9992 1981598 ChemDiv1_025313 Cc1ccc(cc1)C(=O)N/C(=C(\C#N)/[P+](c2ccccc2)(c3ccccc3)c4ccccc4)/S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O14 compound treatment 662185.0 181000.0 0.37 661572.0 181000.0 0.39 0.5399 0.9997 1441887 ChemDiv1_025314 CCOC(=O)c1c(NC(=S)NCC=C)sc2COC(C)(C)Cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O15 compound treatment 705722.0 224000.0 0.46 678364.0 197000.0 0.43 0.6291 0.9992 1981599 ChemDiv1_025315 CCOC(=O)c1cc2C(=O)c3cc(ccc3-c2nc1C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O16 compound treatment 671239.0 190000.0 0.39 672362.0 191000.0 0.41 0.5696 0.9996 1981600 ChemDiv1_025316 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(OC)cc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O17 compound treatment 695540.0 214000.0 0.44 686896.0 206000.0 0.45 0.6273 1.0 1774205 ChemDiv1_025317 Cc1cc-2c(cc1[N+](=O)[O-])C(=O)c3cc4ccccc4nc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O18 compound treatment 691879.0 210000.0 0.43 678622.0 198000.0 0.43 0.6093 1.0 1981601 ChemDiv1_025318 [O-][N+](=O)c1ncn(n1)[C@@H]2[C@H](CC(=CC2=O)c3ccccc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O19 compound treatment 726719.0 245000.0 0.51 685247.0 204000.0 0.44 0.6703 0.9978 1981602 ChemDiv1_025319 COc1ccc(/C=C/2\c3ccc(C)cc3-c4nc5ccccc5cc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O20 compound treatment 735806.0 254000.0 0.52 658547.0 178000.0 0.38 0.6427 0.9883 1504455 ChemDiv1_025320 Cc1cccc(NC(=O)C2CC2c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O21 compound treatment 719394.0 238000.0 0.49 700040.0 219000.0 0.47 0.6823 0.9999 1981603 ChemDiv1_025321 COc1ccc(/C=C/2\c3cc(ccc3-c4c2cc(cc4[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O22 compound treatment 692400.0 211000.0 0.43 677388.0 196000.0 0.43 0.6082 0.9999 1299926 ChemDiv1_025322 COc1cc(ccc1OC(=O)C)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O23 mock treatment 690913.0 209000.0 0.43 670316.0 189000.0 0.41 0.5952 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 O24 mock treatment 325134.0 -157000.0 -0.32 425746.0 -55200.0 -0.12 -0.313 -0.9085 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P01 compound treatment 606054.0 124000.0 0.26 579384.0 98400.0 0.21 0.3322 0.9957 1312865 ChemDiv1_025323 COc1cccc(C2N(CCN2c3ccccc3)c4ccccc4)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P02 compound treatment 639084.0 157000.0 0.32 599995.0 119000.0 0.26 0.4119 0.9934 1981604 ChemDiv1_025324 CC(=O)C1=NN(c2ccccc2Cl)C3(S1)N(N=C(c4ccc(Br)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P03 compound treatment 655136.0 173000.0 0.36 616960.0 136000.0 0.29 0.4613 0.9953 1562244 ChemDiv1_025325 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3cc(Br)ccc3F)sc2=C(C#N)C1c4cc(Br)ccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P04 compound treatment 637631.0 156000.0 0.32 626412.0 145000.0 0.31 0.4502 0.9999 1981605 ChemDiv1_025326 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cccc(C)c4N(C(=O)Cc5ccccc5)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P05 compound treatment 1538154.0 1060000.0 2.18 1345116.0 864000.0 1.87 2.8647 0.9971 1981606 ChemDiv1_025327 CC(C)(C)C(=O)[C@@H]1[C@@H](c2ccc(F)cc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P06 compound treatment 674957.0 193000.0 0.4 632483.0 152000.0 0.33 0.514 0.9953 1981607 ChemDiv1_025328 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)c(OC)c2)n3cccc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P07 compound treatment 680258.0 199000.0 0.41 636273.0 155000.0 0.34 0.5276 0.9951 1125174 ChemDiv1_025329 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(CC)cc3)sc2=C(C#N)C1c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P08 compound treatment 643289.0 162000.0 0.33 640004.0 159000.0 0.34 0.4793 0.9999 1981608 ChemDiv1_025330 CN(C=O)C1(CCCCC1)c2nnnn2c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P09 compound treatment 697545.0 216000.0 0.45 629233.0 148000.0 0.32 0.542 0.987 1981609 ChemDiv1_025331 Fc1cccc(Cl)c1/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P10 compound treatment 702619.0 221000.0 0.46 653242.0 172000.0 0.37 0.5862 0.995 1382128 ChemDiv1_025332 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc(Cl)cc3Cl)sc2=C(C#N)C1c4ccc(Cl)cc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P11 compound treatment 675818.0 194000.0 0.4 632495.0 152000.0 0.33 0.5153 0.9951 1372640 ChemDiv1_025333 Cc1cc(C)c(C2N(Cc3ccccc3)CCN2Cc4ccccc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P12 compound treatment 687282.0 206000.0 0.42 640581.0 160000.0 0.35 0.5444 0.9948 1981610 ChemDiv1_025334 CC(C)(C)C(=O)[C@H]1[C@H](c2ccc(cc2)[N+](=O)[O-])C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P13 compound treatment 684329.0 203000.0 0.42 644513.0 164000.0 0.35 0.5461 0.9965 1981611 ChemDiv1_025335 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCCC3)N1c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P14 compound treatment 662031.0 180000.0 0.37 644823.0 164000.0 0.35 0.514 0.9997 1981612 ChemDiv1_025336 Cc1cccc(c1)n2nnnc2C3(CCCCC3)/N=C/c4ccc(Cl)cc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P15 compound treatment 670773.0 189000.0 0.39 634863.0 154000.0 0.33 0.5116 0.9969 1331962 ChemDiv1_025337 Clc1ccc(cc1)C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P16 compound treatment 677868.0 196000.0 0.4 669396.0 188000.0 0.41 0.5748 1.0 1981613 ChemDiv1_025338 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCC3)N1c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P17 compound treatment 692495.0 211000.0 0.44 657717.0 177000.0 0.38 0.5782 0.9979 1981614 ChemDiv1_025339 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccc(C)cc3)c4cc(OC)ccc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P18 compound treatment 682838.0 201000.0 0.42 647979.0 167000.0 0.36 0.5492 0.9976 1981615 ChemDiv1_025340 CCOc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5cccc(C)c5)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P19 compound treatment 683698.0 202000.0 0.42 668422.0 187000.0 0.41 0.5818 0.9999 1981616 ChemDiv1_025341 Cc1cccc(/N=C/2\NC(=S)N(c3cccc(c3)C(F)(F)F)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P20 compound treatment 692853.0 211000.0 0.44 646296.0 165000.0 0.36 0.5613 0.9952 1719201 ChemDiv1_025342 COc1ccc2N(C(=O)c3ccccc3)C(C)(C)c4ssc(=S)c4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P21 compound treatment 677660.0 196000.0 0.4 658596.0 178000.0 0.38 0.5579 0.9997 1704681 ChemDiv1_025343 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P22 compound treatment 678140.0 196000.0 0.41 651527.0 171000.0 0.37 0.5478 0.9989 1981617 ChemDiv1_025344 CC(C)c1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(Cl)cc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P23 mock treatment 667756.0 186000.0 0.38 633201.0 152000.0 0.33 0.5046 0.9971 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.658 P24 mock treatment 338402.0 -143000.0 -0.3 465183.0 -15800.0 -0.03 -0.2333 -0.7835 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A01 compound treatment 642385.0 171000.0 0.35 615457.0 146000.0 0.32 0.4733 0.9984 1981618 ChemDiv1_025345 O=C(COC(=O)c1cc2C3C=CCC3CN4CC5CC=CC5c(c1)c42)c6ccc(cc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A02 compound treatment 643722.0 173000.0 0.36 591493.0 122000.0 0.26 0.4385 0.9892 1981619 ChemDiv1_025346 CCOC(=O)c1ccc(cc1)N2C(=O)/C(=C/c3ccc(Cl)cc3)/C=C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A03 compound treatment 637977.0 167000.0 0.34 594192.0 125000.0 0.27 0.4343 0.9928 1699633 ChemDiv1_025347 CCOC(=O)COc1ccc(cc1)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A04 compound treatment 633925.0 163000.0 0.34 600107.0 131000.0 0.28 0.4374 0.9963 1981620 ChemDiv1_025348 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5[N+](=O)[O-])C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A05 compound treatment 660888.0 190000.0 0.39 624773.0 155000.0 0.34 0.5145 0.9971 1981621 ChemDiv1_025349 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(Br)cc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A06 compound treatment 682470.0 211000.0 0.44 618170.0 149000.0 0.32 0.5359 0.9888 1653004 ChemDiv1_025350 Cc1ccccc1C2(CC2C(=O)Nc3ccccc3)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A07 compound treatment 679429.0 208000.0 0.43 651778.0 182000.0 0.39 0.5829 0.9991 1981622 ChemDiv1_025351 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccccc2I)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A08 compound treatment 695515.0 224000.0 0.46 640136.0 171000.0 0.37 0.5886 0.9937 1981623 ChemDiv1_025352 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)c(OC)c2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A09 compound treatment 671104.0 200000.0 0.41 648136.0 179000.0 0.39 0.5652 0.9995 1981624 ChemDiv1_025353 CCc1ccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6[N+](=O)[O-])c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A10 compound treatment 736170.0 265000.0 0.55 649913.0 180000.0 0.39 0.6629 0.9864 1981625 ChemDiv1_025354 O=P(Cc1cccc(CP(=O)(c2ccccc2)c3ccccc3)n1)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A11 compound treatment 704193.0 233000.0 0.48 641425.0 172000.0 0.37 0.6032 0.992 1981626 ChemDiv1_025355 CCc1ccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6Cl)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A12 compound treatment 693849.0 223000.0 0.46 628217.0 159000.0 0.34 0.5679 0.9897 1117632 ChemDiv1_025356 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(OCC=C)cc3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A13 compound treatment 705001.0 234000.0 0.48 633205.0 164000.0 0.35 0.5918 0.9885 1638806 ChemDiv1_025357 COc1c(I)cccc1C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A14 compound treatment 720576.0 249000.0 0.51 635850.0 166000.0 0.36 0.6186 0.9847 1981627 ChemDiv1_025358 Nc1nonc1n2nnc(C(=O)N/N=C/c3cccc(Cl)c3Cl)c2CN4CCCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A15 compound treatment 701389.0 230000.0 0.48 648110.0 179000.0 0.39 0.6094 0.9948 1981628 ChemDiv1_025359 Cc1cccc(c1)n2nnnc2C3(CCCCC3)/N=C/c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A16 compound treatment 715846.0 245000.0 0.51 658659.0 189000.0 0.41 0.6466 0.9946 1074320 ChemDiv1_025360 O=C1c2ccccc2-c3ncccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A17 compound treatment 707388.0 236000.0 0.49 662553.0 193000.0 0.42 0.6402 0.9971 1981629 ChemDiv1_025361 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(OC)c2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A18 compound treatment 706399.0 235000.0 0.49 635654.0 166000.0 0.36 0.5976 0.9891 1779312 ChemDiv1_025362 Cc1ccc(cc1NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A19 compound treatment 700507.0 229000.0 0.47 642903.0 173000.0 0.38 0.6001 0.9934 1981630 ChemDiv1_025363 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(cc3)[N+](=O)[O-])O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A20 compound treatment 683844.0 213000.0 0.44 633604.0 164000.0 0.36 0.5616 0.9945 1213828 ChemDiv1_025364 CC(C)c1ccc(cc1)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A21 compound treatment 669772.0 199000.0 0.41 624700.0 155000.0 0.34 0.5274 0.9951 1125630 ChemDiv1_025365 CCc1ccc(cc1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A22 compound treatment 662507.0 191000.0 0.39 617762.0 148000.0 0.32 0.5062 0.9947 1549776 ChemDiv1_025366 CN(C)c1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A23 mock treatment 607527.0 136000.0 0.28 588977.0 119000.0 0.26 0.3819 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 A24 mock treatment 236314.0 -235000.0 -0.48 200344.0 -269000.0 -0.58 -0.7548 -0.9958 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B01 compound treatment 642442.0 171000.0 0.35 583920.0 114000.0 0.25 0.4251 0.9849 1292383 ChemDiv1_025367 COc1ccc(cc1)c2nn(CN3CCC(CC3)C(=O)N)c(=S)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B02 compound treatment 657950.0 187000.0 0.39 621654.0 152000.0 0.33 0.5055 0.9969 1981631 ChemDiv1_025368 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)c4ccc(Br)cc4)/C=C2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B03 compound treatment 859634.0 388000.0 0.8 802711.0 333000.0 0.72 1.077 0.9986 1981632 ChemDiv1_025369 NC1=C(C#N)C2=CCCCC2C(c3cccc4ccccc34)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B04 compound treatment 692783.0 222000.0 0.46 646352.0 177000.0 0.38 0.5941 0.9961 1981633 ChemDiv1_025370 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cccc(Br)c4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B05 compound treatment 739709.0 268000.0 0.55 681694.0 212000.0 0.46 0.7167 0.9956 1479652 ChemDiv1_025371 Clc1cccc(NC(=O)C2(CCCCC2)NC(=O)COc3ccc(Cl)cc3Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B06 compound treatment 716532.0 245000.0 0.51 670992.0 202000.0 0.44 0.6665 0.9972 1981634 ChemDiv1_025372 CN1C(=O)N(C)C2(N=c3sc(=Cc4cccc(c4)[N+](=O)[O-])c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B07 compound treatment 750669.0 279000.0 0.58 709755.0 240000.0 0.52 0.7756 0.9987 1165189 ChemDiv1_025373 Brc1cccc(c1)c2nn(CN3CCCCC3)c(=S)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B08 compound treatment 727370.0 256000.0 0.53 690903.0 221000.0 0.48 0.7128 0.9988 1981635 ChemDiv1_025374 CCCCCCCCCCCCN1C(=O)OC2(CCCCC2)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B09 compound treatment 881421.0 410000.0 0.85 793492.0 324000.0 0.7 1.0947 0.9956 1981636 ChemDiv1_025375 CSc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B10 compound treatment 738502.0 267000.0 0.55 711345.0 242000.0 0.52 0.7603 0.9997 1573467 ChemDiv1_025376 Cc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B11 compound treatment 667908.0 197000.0 0.41 677122.0 208000.0 0.45 0.6049 0.9987 1981637 ChemDiv1_025377 OC(=O)c1ccc2NC(C3CC(Sc4ccccc4[N+](=O)[O-])C(Cl)C3c2c1)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B12 compound treatment 714632.0 243000.0 0.5 685900.0 216000.0 0.47 0.6865 0.9994 1981638 ChemDiv1_025378 CC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B13 compound treatment 769519.0 298000.0 0.62 706683.0 237000.0 0.51 0.7985 0.9959 1981639 ChemDiv1_025379 COc1ccc(cc1)N2C(=O)C3ON(C4SC(=S)N(C)C4(C)C)C(C3C2=O)c5cccc(c5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B14 compound treatment 744370.0 273000.0 0.56 698722.0 229000.0 0.5 0.7496 0.998 1180464 ChemDiv1_025380 CN1C(=S)NC(C)(C)CC1(C)c2ccc(OC(=O)C)cc2OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B15 compound treatment 777553.0 306000.0 0.63 723406.0 254000.0 0.55 0.8358 0.9976 1981640 ChemDiv1_025381 OC1=C(C(N(C1=O)c2ccc(Br)cc2)c3ccc(Br)cc3)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B16 compound treatment 764943.0 294000.0 0.61 726478.0 257000.0 0.56 0.8221 0.9991 1945240 ChemDiv1_025382 Clc1ccccc1C=c2sc3nnc(c4ccccc4Cl)n3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B17 compound treatment 824542.0 353000.0 0.73 806818.0 337000.0 0.73 1.032 1.0 1495269 ChemDiv1_025383 N#CC(=C1NC2(CCCCC2)Cc3ccccc13)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B18 compound treatment 762267.0 291000.0 0.6 700156.0 231000.0 0.5 0.7779 0.9958 1981641 ChemDiv1_025384 N(=c1scc(c2ccc(cc2)c3ccccc3)n1c4ccccc4)c5ccccn5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B19 compound treatment 743172.0 272000.0 0.56 665302.0 196000.0 0.42 0.6967 0.9904 1981642 ChemDiv1_025385 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B20 compound treatment 729454.0 258000.0 0.53 681054.0 212000.0 0.46 0.7007 0.9971 1981643 ChemDiv1_025386 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc(Br)cc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B21 compound treatment 761870.0 291000.0 0.6 699081.0 230000.0 0.5 0.7757 0.9956 1981644 ChemDiv1_025387 Clc1ccccc1c2nnc3sc(=Cc4ccc(Br)cc4)c(=O)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B22 compound treatment 714633.0 243000.0 0.5 665142.0 196000.0 0.42 0.6548 0.9964 1734017 ChemDiv1_025388 Cc1ccc(cc1)N2CCN(C2c3cc(Cl)cc(Cl)c3O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B23 mock treatment 694238.0 223000.0 0.46 654714.0 185000.0 0.4 0.609 0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 B24 mock treatment 222659.0 -249000.0 -0.51 250011.0 -219000.0 -0.48 -0.6987 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C01 compound treatment 632649.0 161000.0 0.33 599045.0 130000.0 0.28 0.4339 0.9963 1528900 ChemDiv1_025389 Cc1cccc(c1)N2C(=O)C3C(C2=O)C4(C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C02 compound treatment 671969.0 201000.0 0.41 639622.0 170000.0 0.37 0.5534 0.9983 1981645 ChemDiv1_025390 [O-][N+](=O)c1ccccc1N2C(=O)C3C(C2=O)C4(/C=N/c5cccc(Cl)c5Cl)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C03 compound treatment 689231.0 218000.0 0.45 684611.0 215000.0 0.47 0.6475 0.9999 1981646 ChemDiv1_025391 Cc1ccc2/C(=N\c3ccccc3)/c4cc5ccccc5nc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C04 compound treatment 682992.0 212000.0 0.44 672807.0 203000.0 0.44 0.6203 1.0 1981647 ChemDiv1_025392 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)c(OC)c2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C05 compound treatment 716207.0 245000.0 0.51 721163.0 252000.0 0.54 0.7428 0.9993 1981648 ChemDiv1_025393 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(OC)c(OC)c(OC)c2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C06 compound treatment 687532.0 216000.0 0.45 703417.0 234000.0 0.51 0.6738 0.998 1981649 ChemDiv1_025394 Cc1cccc2-c3c(ssc3=Nc4cccc(Cl)c4C)C(C)(C)Nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C07 compound treatment 732995.0 262000.0 0.54 721741.0 252000.0 0.55 0.7682 1.0 1981650 ChemDiv1_025395 Cc1cc2Cc3cccnc3-c2cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C08 compound treatment 745100.0 274000.0 0.57 743252.0 274000.0 0.59 0.8188 0.9997 1981651 ChemDiv1_025396 CCCS(=O)(=O)c1c(C(=O)N/N=C/C=C/c2ccccc2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C09 compound treatment 754095.0 283000.0 0.58 718987.0 250000.0 0.54 0.7948 0.9992 1981652 ChemDiv1_025397 OC(=O)C1C(C(=O)NCc2ccccc2)C3(Br)c4ccccc4C1(Br)c5ccccc53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C10 compound treatment 1209934.0 739000.0 1.52 1119685.0 650000.0 1.41 2.0734 0.9992 1981653 ChemDiv1_025398 Cc1ccc(cc1C)N2C(=O)/C(=C/c3ccc(Cl)cc3)/C=C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C11 compound treatment 760309.0 289000.0 0.6 736047.0 267000.0 0.58 0.83 0.9999 1981654 ChemDiv1_025399 CCCS(=O)(=O)c1c(C(=O)N/N=C/C=C/c2ccccc2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C12 compound treatment 755163.0 284000.0 0.59 701775.0 232000.0 0.5 0.77 0.9971 1981655 ChemDiv1_025400 CCCCCOc1ccc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C13 compound treatment 776771.0 306000.0 0.63 731638.0 262000.0 0.57 0.8472 0.9986 1981656 ChemDiv1_025401 Brc1ccc(cc1)N2N=C(SC23N(N=C(c4ccc(Br)cc4)c5ccccc53)c6ccccc6)C(=O)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C14 compound treatment 768733.0 298000.0 0.61 746126.0 277000.0 0.6 0.8577 0.9999 1981657 ChemDiv1_025402 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5ccc(C)cc5C)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C15 compound treatment 761154.0 290000.0 0.6 767926.0 298000.0 0.65 0.88 0.9993 1981658 ChemDiv1_025403 Cc1cccc(/N=C/2\NC(=S)N(c3ccc(Cl)cc3)C42CCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C16 compound treatment 758868.0 288000.0 0.59 736671.0 267000.0 0.58 0.8288 0.9999 1774207 ChemDiv1_025404 Cc1cc2C(=O)c3cccnc3-c2cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C17 compound treatment 769849.0 299000.0 0.62 745946.0 276000.0 0.6 0.859 0.9999 1981659 ChemDiv1_025405 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(c2)[N+](=O)[O-])n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C18 compound treatment 731273.0 260000.0 0.54 694643.0 225000.0 0.49 0.7242 0.9988 1981660 ChemDiv1_025406 O=C1C2C(C3C(=O)CC2c4ccccc34)C(=O)N1c5cccnc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C19 compound treatment 734434.0 263000.0 0.54 708427.0 239000.0 0.52 0.7499 0.9997 1981661 ChemDiv1_025407 Cc1ccc(Cl)cc1/N=C/2\NC(=S)N(c3ccc(O)cc3)C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C20 compound treatment 752096.0 281000.0 0.58 752413.0 283000.0 0.61 0.843 0.9996 1981662 ChemDiv1_025408 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccccc2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C21 compound treatment 740389.0 269000.0 0.56 718014.0 249000.0 0.54 0.7733 0.9999 1981663 ChemDiv1_025409 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5cccc(Cl)c5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C22 compound treatment 1076964.0 606000.0 1.25 808203.0 339000.0 0.73 1.4026 0.9676 1245614 ChemDiv1_025410 Cc1cccc(c1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C23 mock treatment 689260.0 218000.0 0.45 693964.0 224000.0 0.49 0.6618 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 C24 mock treatment 221214.0 -250000.0 -0.52 252691.0 -217000.0 -0.47 -0.6967 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D01 compound treatment 619590.0 148000.0 0.31 592321.0 123000.0 0.27 0.4046 0.9975 1981664 ChemDiv1_025411 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D02 compound treatment 662267.0 191000.0 0.39 632611.0 163000.0 0.35 0.5285 0.9985 1981665 ChemDiv1_025412 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5ccc(C)cc5)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D03 compound treatment 695539.0 224000.0 0.46 654851.0 185000.0 0.4 0.6111 0.9974 1981666 ChemDiv1_025413 [O-][n+]1ccc(CP(=O)(c2ccccc2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D04 compound treatment 688410.0 217000.0 0.45 651197.0 182000.0 0.39 0.5951 0.9979 1981667 ChemDiv1_025414 Sc1nnc2c3ccccc3n(CC=C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D05 compound treatment 725680.0 254000.0 0.53 694408.0 225000.0 0.49 0.7157 0.9993 1694880 ChemDiv1_025415 Clc1cccc(NC(=O)C2(CCCCC2)NC(=O)c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D06 compound treatment 758039.0 287000.0 0.59 710837.0 241000.0 0.52 0.7881 0.998 1661056 ChemDiv1_025416 CN(C)c1ccc(C=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D07 compound treatment 787393.0 316000.0 0.65 705166.0 236000.0 0.51 0.8222 0.9926 1739271 ChemDiv1_025417 NC(=O)C1CCN(Cn2nc(c3cccc(F)c3)n(c4ccccc4)c2=S)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D08 compound treatment 751376.0 280000.0 0.58 718624.0 249000.0 0.54 0.7902 0.9994 1981668 ChemDiv1_025418 COc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D09 compound treatment 779324.0 308000.0 0.64 599291.0 130000.0 0.28 0.6484 0.9325 1377732 ChemDiv1_025419 Cc1cc(C)c(C2N(CCN2c3ccccc3)c4ccccc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D10 compound treatment 817542.0 346000.0 0.71 790391.0 321000.0 0.69 0.9967 0.9999 1127425 ChemDiv1_025420 O=C1c2ccccc2-c3ccc(cc13)c4nc([nH]c4c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D11 compound treatment 674472.0 203000.0 0.42 627723.0 158000.0 0.34 0.5389 0.9949 1981669 ChemDiv1_025421 OC(=O)c1ccc2NC(C3CC(Sc4ccccc4[N+](=O)[O-])C(Cl)C3c2c1)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D12 compound treatment 757956.0 287000.0 0.59 693226.0 224000.0 0.48 0.761 0.995 1981670 ChemDiv1_025422 COc1ccc(CCN2C(=O)C3C(C4C(=O)CC3c5ccccc45)C2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D13 compound treatment 792455.0 321000.0 0.66 699426.0 230000.0 0.5 0.8208 0.99 1981671 ChemDiv1_025423 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(c(OS(=O)(=O)c3ccc(C)cc3)c2)C4(C)CC(C)(C)NC(=S)N4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D14 compound treatment 780446.0 309000.0 0.64 669581.0 200000.0 0.43 0.7576 0.9821 1479101 ChemDiv1_025424 COc1ccc(NC(=O)C2C3CCCC2C3c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D15 compound treatment 809018.0 338000.0 0.7 739561.0 270000.0 0.58 0.9064 0.9962 1981672 ChemDiv1_025425 COc1cc(/C=C/2\CCC/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D16 compound treatment 792150.0 321000.0 0.66 722200.0 253000.0 0.55 0.8552 0.9955 1981673 ChemDiv1_025426 CC(=O)C1=NN(C(N1c2ccc(cc2)N3CCOCC3)c4ccc5OCOc5c4)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D17 compound treatment 782782.0 312000.0 0.64 688130.0 219000.0 0.47 0.7894 0.9886 1981674 ChemDiv1_025427 FC(F)(F)C1(N=C(OC(=N1)c2cccc(Cl)c2)N3CCCCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D18 compound treatment 740446.0 269000.0 0.56 705691.0 236000.0 0.51 0.7545 0.9991 1717800 ChemDiv1_025428 N(=c1scc(c2ccccc2)n1c3ccccc3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D19 compound treatment 791123.0 320000.0 0.66 794544.0 325000.0 0.7 0.9645 0.9995 1981675 ChemDiv1_025429 COc1ccc(/C=N/c2cc3C(CCN4CCC(c5ccccc5)c(c2)c43)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D20 compound treatment 739130.0 268000.0 0.55 695264.0 226000.0 0.49 0.7366 0.9981 1981676 ChemDiv1_025430 FC(F)(F)C1(N=C(OC(=N1)c2ccco2)N3CCOCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D21 compound treatment 760554.0 289000.0 0.6 740134.0 271000.0 0.59 0.8366 1.0 1231862 ChemDiv1_025431 CCN(CC)c1ccc(cc1)C2N(CCN2S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D22 compound treatment 738469.0 267000.0 0.55 696293.0 227000.0 0.49 0.7372 0.9983 1239261 ChemDiv1_025432 Cc1ccc(NC(=O)C2C3CCCC2C3c4ccccc4)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D23 mock treatment 706600.0 235000.0 0.49 680555.0 211000.0 0.46 0.6666 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 D24 mock treatment 232408.0 -239000.0 -0.49 210176.0 -259000.0 -0.56 -0.7454 -0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E01 compound treatment 596782.0 126000.0 0.26 605107.0 136000.0 0.29 0.3909 0.9981 1935645 ChemDiv1_025433 COc1ccc(cc1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E02 compound treatment 642103.0 171000.0 0.35 636270.0 167000.0 0.36 0.5047 0.9999 1981677 ChemDiv1_025434 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccncc2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E03 compound treatment 687013.0 216000.0 0.45 691369.0 222000.0 0.48 0.6546 0.9993 1981678 ChemDiv1_025435 Cc1cccc(/N=C/2\c3ccccc3-c4nc5ccccc5cc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E04 compound treatment 677597.0 206000.0 0.43 686739.0 217000.0 0.47 0.6338 0.9988 1540563 ChemDiv1_025436 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(OC(=O)c5ccccc5)cc4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E05 compound treatment 716505.0 245000.0 0.51 721800.0 252000.0 0.55 0.7442 0.9993 1981679 ChemDiv1_025437 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(cc2)N(C)C)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E06 compound treatment 712195.0 241000.0 0.5 670130.0 201000.0 0.43 0.6588 0.9977 1981680 ChemDiv1_025438 CCc1ccc(N=c2ssc3c2-c4cc(C)ccc4NC3(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E07 compound treatment 732416.0 261000.0 0.54 658278.0 189000.0 0.41 0.6702 0.9906 1981681 ChemDiv1_025439 Cc1ccc(/N=C\2/c3ccccc3-c4ncccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E08 compound treatment 732905.0 262000.0 0.54 714744.0 245000.0 0.53 0.7573 1.0 1981682 ChemDiv1_025440 Clc1ccc(C(=O)N/N=C/c2ccc(Sc3nnc(c4ccccc4)n3c5ccccc5)o2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E09 compound treatment 751154.0 280000.0 0.58 711550.0 242000.0 0.52 0.7791 0.9988 1981683 ChemDiv1_025441 Ic1ccc(/C=N/c2oc(c(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E10 compound treatment 754892.0 284000.0 0.59 731705.0 262000.0 0.57 0.8154 0.9999 1651501 ChemDiv1_025442 COC(=O)c1ccc(NC(=O)C2CC2(c3cccc(C)c3)c4cccc(C)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E11 compound treatment 791915.0 321000.0 0.66 685359.0 216000.0 0.47 0.7985 0.9854 1981684 ChemDiv1_025443 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)cc2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E12 compound treatment 758373.0 287000.0 0.59 700711.0 231000.0 0.5 0.773 0.9965 1551232 ChemDiv1_025444 COc1ccc(cc1OC)c2nn(CN3CCC(C)CC3)c(=S)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E13 compound treatment 797089.0 326000.0 0.67 671903.0 202000.0 0.44 0.7855 0.9784 1981685 ChemDiv1_025445 [O-][N+](=O)c1cc2c3N(CCC2(c4ccccc4)c5ccccc5)CCC(c6ccccc6)(c7ccccc7)c3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E14 compound treatment 759435.0 288000.0 0.59 746004.0 277000.0 0.6 0.8439 1.0 1981686 ChemDiv1_025446 Cc1ccccc1N2C(=O)C3C(C(CCC3c4ccccc4)c5ccccc5)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E15 compound treatment 778626.0 307000.0 0.63 747240.0 278000.0 0.6 0.8738 0.9996 1981687 ChemDiv1_025447 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCC3)N1c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E16 compound treatment 744352.0 273000.0 0.56 702741.0 233000.0 0.5 0.7557 0.9985 1334944 ChemDiv1_025448 CC1=C(C#Cc2ccccc2)c3ccccc3OC1(NCc4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E17 compound treatment 777196.0 306000.0 0.63 732027.0 263000.0 0.57 0.8484 0.9986 1981688 ChemDiv1_025449 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccccc2I)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E18 compound treatment 737898.0 267000.0 0.55 716760.0 247000.0 0.54 0.7677 0.9999 1352990 ChemDiv1_025450 COc1ccc(cc1OC)C2N(CCO)C(=O)C(=C2C(=O)c3ccc(Cl)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E19 compound treatment 745808.0 275000.0 0.57 709937.0 240000.0 0.52 0.7688 0.9991 1981689 ChemDiv1_025451 Cc1ccsc1/C=N/NC(=O)c2nnn(c3nonc3N)c2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E20 compound treatment 736114.0 265000.0 0.55 699061.0 230000.0 0.5 0.738 0.9989 1498450 ChemDiv1_025452 CCc1ccccc1NC(=O)C2CC2(c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E21 compound treatment 851060.0 380000.0 0.78 806225.0 337000.0 0.73 1.0698 0.9993 1554746 ChemDiv1_025453 O=C([C@@H]1[C@@H](c2ccccc2)C(C#N)(C#N)[C@@H]3N1C=Cc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E22 compound treatment 715888.0 245000.0 0.51 691939.0 222000.0 0.48 0.6976 0.9997 1981690 ChemDiv1_025454 COc1cccc(CSC2=C(C#N)[C@@H](C(=C(C)N2)C(=O)C)c3ccccc3[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E23 mock treatment 692207.0 221000.0 0.46 700670.0 231000.0 0.5 0.6764 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 E24 mock treatment 209265.0 -262000.0 -0.54 266755.0 -203000.0 -0.44 -0.6926 -0.9946 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F01 compound treatment 611871.0 141000.0 0.29 611058.0 142000.0 0.31 0.422 0.9996 1981691 ChemDiv1_025455 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F02 compound treatment 657479.0 186000.0 0.38 647262.0 178000.0 0.38 0.544 1.0 1981692 ChemDiv1_025456 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5cccc(Cl)c5)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F03 compound treatment 717576.0 246000.0 0.51 703289.0 234000.0 0.51 0.7174 1.0 1981693 ChemDiv1_025457 CC(C)Sc1nnc2c3ccccc3n(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F04 compound treatment 694624.0 223000.0 0.46 833716.0 364000.0 0.79 0.8836 0.9674 1044658 ChemDiv1_025458 Sc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F05 compound treatment 729322.0 258000.0 0.53 705052.0 236000.0 0.51 0.7373 0.9998 1320011 ChemDiv1_025459 Cc1cc(I)cc(C)c1NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F06 compound treatment 755459.0 284000.0 0.59 700639.0 231000.0 0.5 0.7687 0.9969 1933230 ChemDiv1_025460 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccc(cc4)[N+](=O)[O-])c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F07 compound treatment 738028.0 267000.0 0.55 733713.0 264000.0 0.57 0.7939 0.9998 1614830 ChemDiv1_025461 CC1CCN(Cn2nc(c3cccc(F)c3)n(c4ccccc4)c2=S)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F08 compound treatment 763981.0 293000.0 0.6 723933.0 254000.0 0.55 0.8168 0.9989 1372156 ChemDiv1_025462 COc1ccc(cc1OC)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F09 compound treatment 785930.0 315000.0 0.65 750786.0 281000.0 0.61 0.8899 0.9995 1569286 ChemDiv1_025463 CC(=O)OC1C(OC(=O)c2ccc(C)cc2)C(COC(=O)c3ccc(C)cc3)OC1n4cc(I)c(=O)[nH]c4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F10 compound treatment 767559.0 296000.0 0.61 709051.0 240000.0 0.52 0.7992 0.9966 1981694 ChemDiv1_025464 CCOC(=O)C1(C)C=C(Nc2ccc(cc2)[N+](=O)[O-])C(=O)N1c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F11 compound treatment 786328.0 315000.0 0.65 631519.0 162000.0 0.35 0.708 0.958 1340324 ChemDiv1_025465 CSc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F12 compound treatment 786174.0 315000.0 0.65 691716.0 222000.0 0.48 0.7999 0.989 1339187 ChemDiv1_025466 CC1CCC(CC1)(NC(=O)COc2ccc(Cl)cc2Cl)C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F13 compound treatment 787907.0 317000.0 0.65 676291.0 207000.0 0.45 0.7788 0.9829 1981695 ChemDiv1_025467 CC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F14 compound treatment 743687.0 272000.0 0.56 744755.0 275000.0 0.6 0.819 0.9996 1782327 ChemDiv1_025468 COC(=O)C1(O)N(C(=O)C(=C1C(=O)c2ccc(cc2)[N+](=O)[O-])O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F15 compound treatment 745145.0 274000.0 0.57 747784.0 278000.0 0.6 0.8258 0.9995 1981696 ChemDiv1_025469 CC(C)c1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F16 compound treatment 780048.0 309000.0 0.64 723900.0 254000.0 0.55 0.8402 0.9973 1363708 ChemDiv1_025470 CCc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F17 compound treatment 796753.0 326000.0 0.67 738638.0 269000.0 0.58 0.8871 0.9975 1537952 ChemDiv1_025471 O=C1C2C(C(=O)N1Cc3ccccc3)C4(C#N)c5ccccc5C2c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F18 compound treatment 766152.0 295000.0 0.61 690434.0 221000.0 0.48 0.7687 0.9929 1981697 ChemDiv1_025472 N(=c1scc(c2ccc(cc2)c3ccccc3)n1c4ccccc4)c5nc(cs5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F19 compound treatment 785962.0 315000.0 0.65 530511.0 61000.0 0.13 0.5528 0.8338 1981698 ChemDiv1_025473 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OCc5ccccc5)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F20 compound treatment 705330.0 234000.0 0.48 678961.0 209000.0 0.45 0.6623 0.9995 1981699 ChemDiv1_025474 CCN(CC)C1=NC(N=C(O1)c2cccc(Cl)c2)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F21 compound treatment 758844.0 288000.0 0.59 746339.0 277000.0 0.6 0.8436 1.0 1458269 ChemDiv1_025475 CCN(CC)Cc1c(nnn1c2nonc2N)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F22 compound treatment 737149.0 266000.0 0.55 711477.0 242000.0 0.52 0.7585 0.9997 1780522 ChemDiv1_025476 Brc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F23 mock treatment 721460.0 250000.0 0.52 684416.0 215000.0 0.47 0.6942 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 F24 mock treatment 246953.0 -224000.0 -0.46 201883.0 -268000.0 -0.58 -0.7369 -0.9938 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G01 compound treatment 596141.0 125000.0 0.26 593983.0 124000.0 0.27 0.3729 0.9998 1935517 ChemDiv1_025477 Fc1ccc(cc1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G02 compound treatment 652492.0 181000.0 0.37 648925.0 179000.0 0.39 0.5392 0.9998 1981700 ChemDiv1_025478 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(c2)[N+](=O)[O-])n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G03 compound treatment 685257.0 214000.0 0.44 674906.0 205000.0 0.44 0.6268 1.0 1981701 ChemDiv1_025479 N#CCCC1(CCC#N)c2ccccc2-c3nc4ccccc4cc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G04 compound treatment 679601.0 208000.0 0.43 687816.0 218000.0 0.47 0.6383 0.9989 1981702 ChemDiv1_025480 Cc1ccc(Cl)cc1/N=C/2\NC(=S)N(Cc3c(F)cccc3F)C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G05 compound treatment 714061.0 243000.0 0.5 713243.0 244000.0 0.53 0.7275 0.9997 1981703 ChemDiv1_025481 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(OC)c(OC)c(OC)c2)n3cccc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G06 compound treatment 683718.0 213000.0 0.44 682427.0 213000.0 0.46 0.6361 0.9997 1981704 ChemDiv1_025482 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccccc3I)c4cc(OC)ccc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G07 compound treatment 729984.0 259000.0 0.53 716122.0 247000.0 0.53 0.7552 1.0 1927724 ChemDiv1_025483 Cc1ccc(cc1)C(=O)N2CCN(C2)C(=O)CN3CCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G08 compound treatment 751283.0 280000.0 0.58 726101.0 257000.0 0.56 0.8016 0.9998 1981705 ChemDiv1_025484 CN(C)c1ccc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G09 compound treatment 761371.0 290000.0 0.6 742194.0 273000.0 0.59 0.8409 1.0 1981706 ChemDiv1_025485 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2c[nH]c3ccccc23)n4ccccc4c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G10 compound treatment 745693.0 274000.0 0.57 669349.0 200000.0 0.43 0.7065 0.9911 1306837 ChemDiv1_025486 C=CCNC(=O)C1CC2c3ccccc3C1c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G11 compound treatment 756595.0 285000.0 0.59 727014.0 258000.0 0.56 0.8107 0.9996 1981707 ChemDiv1_025487 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(cc2)N(C)C)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G12 compound treatment 745249.0 274000.0 0.57 672498.0 203000.0 0.44 0.7107 0.9922 1981708 ChemDiv1_025488 CCc1ccccc1/N=C\C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(OC)cc6)c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G13 compound treatment 780099.0 309000.0 0.64 749235.0 280000.0 0.61 0.879 0.9997 1981709 ChemDiv1_025489 Oc1cc2ccccc2cc1C(=O)N/N=C/c3ccc(Sc4nnc(c5ccccc5)n4c6ccccc6)o3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G14 compound treatment 741612.0 270000.0 0.56 700889.0 231000.0 0.5 0.7489 0.9985 1981710 ChemDiv1_025490 COc1cc(C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5)c(Br)cc1OCc6ccc(Cl)cc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G15 compound treatment 756033.0 285000.0 0.59 735974.0 266000.0 0.58 0.8236 1.0 1981711 ChemDiv1_025491 Cc1cccc(c1)n2nnnc2C3(CCCCC3)/N=C/c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G16 compound treatment 751980.0 281000.0 0.58 729537.0 260000.0 0.56 0.8078 0.9999 1981712 ChemDiv1_025492 COc1cc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)cc(Br)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G17 compound treatment 789712.0 319000.0 0.66 757962.0 288000.0 0.62 0.9064 0.9997 1981713 ChemDiv1_025493 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(F)c2)n3cccc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G18 compound treatment 703294.0 232000.0 0.48 689428.0 220000.0 0.48 0.6754 1.0 1424905 ChemDiv1_025494 OC1=C(C(N(C1=O)c2ccc(O)cc2)c3ccccc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G19 compound treatment 746425.0 275000.0 0.57 717757.0 248000.0 0.54 0.7817 0.9996 1689354 ChemDiv1_025495 Brc1ccc(OC(=O)c2ccccc2)c(c1)C3NC(=O)c4c5CCCCc5sc4N3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G20 compound treatment 731045.0 260000.0 0.54 689058.0 220000.0 0.48 0.7153 0.9982 1704458 ChemDiv1_025496 CN1C(=S)NC(C)(C)CC1(C)c2ccc(O)cc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G21 compound treatment 748921.0 278000.0 0.57 688110.0 219000.0 0.47 0.74 0.9955 1981714 ChemDiv1_025497 Cc1cccc(c1)N2C(=O)C3CCC(C)(C2=O)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G22 compound treatment 771333.0 300000.0 0.62 781431.0 312000.0 0.68 0.9155 0.9991 1981715 ChemDiv1_025498 FC(F)(F)c1ccc(cc1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G23 mock treatment 697293.0 226000.0 0.47 733284.0 264000.0 0.57 0.7337 0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 G24 mock treatment 246597.0 -225000.0 -0.46 205527.0 -264000.0 -0.57 -0.7318 -0.9946 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H01 compound treatment 629300.0 158000.0 0.33 610308.0 141000.0 0.3 0.4463 0.9994 1681287 ChemDiv1_025499 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccccc3F)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H02 compound treatment 659204.0 188000.0 0.39 629668.0 160000.0 0.35 0.5196 0.9984 1935649 ChemDiv1_025500 Cc1ccc(cc1S(=O)(=O)n2nnc3ccccc23)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H03 compound treatment 710894.0 240000.0 0.49 696176.0 227000.0 0.49 0.6968 1.0 1981716 ChemDiv1_025501 CN1C(=S)SC(N2OC3C(C2c4ccc(Cl)cc4)C(=O)N(C3=O)c5ccccc5)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H04 compound treatment 701175.0 230000.0 0.47 662908.0 193000.0 0.42 0.6317 0.998 1447750 ChemDiv1_025502 COC(=O)c1nnn(c1CN2CCOCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H05 compound treatment 703848.0 233000.0 0.48 637534.0 168000.0 0.36 0.5968 0.9906 1981717 ChemDiv1_025503 CCCCCCCCCCCCN1C(=C)C2(CCCCC2)OC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H06 compound treatment 753741.0 283000.0 0.58 683379.0 214000.0 0.46 0.7398 0.9935 1701939 ChemDiv1_025504 CC1(C)CC2(CC(Oc3cc(O)ccc32)c4ccccc4)NC(=S)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H07 compound treatment 763461.0 292000.0 0.6 713930.0 244000.0 0.53 0.8007 0.9979 1981718 ChemDiv1_025505 O=C(CSc1nnc2c3ccccc3[nH]c2n1)NCCOc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H08 compound treatment 769162.0 298000.0 0.62 716804.0 247000.0 0.54 0.8134 0.9976 1318610 ChemDiv1_025506 OC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H09 compound treatment 781939.0 311000.0 0.64 744117.0 275000.0 0.59 0.8739 0.9993 1981719 ChemDiv1_025507 Cc1cccc(N2C(=O)C3C(C(CCC3c4ccccc4)c5ccccc5)C2=O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H10 compound treatment 769272.0 298000.0 0.62 737729.0 268000.0 0.58 0.8456 0.9996 1359326 ChemDiv1_025508 Cn1c(CC(=O)Nc2ccccc2)c(Sc3ccccc3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H11 compound treatment 762134.0 291000.0 0.6 660480.0 191000.0 0.41 0.717 0.9834 1241527 ChemDiv1_025509 COc1cc(ccc1OC(=O)C)C2N(CCN2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H12 compound treatment 727705.0 256000.0 0.53 691418.0 222000.0 0.48 0.7141 0.9988 1981720 ChemDiv1_025510 Brc1cccc(NC2=CC(N(C2=O)c3cccc(Br)c3)c4cccc5ccccc45)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H13 compound treatment 746471.0 275000.0 0.57 703233.0 234000.0 0.51 0.7595 0.9983 1981721 ChemDiv1_025511 CC(=O)C1=NN(c2ccccc2C)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H14 compound treatment 747959.0 277000.0 0.57 695510.0 226000.0 0.49 0.7499 0.997 1981722 ChemDiv1_025512 CC(C)(C)c1ccc(cc1)C2C=C(Nc3cccc(Cl)c3)C(=O)N2c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H15 compound treatment 750021.0 279000.0 0.58 696780.0 227000.0 0.49 0.7548 0.9969 1981723 ChemDiv1_025513 CCCn1c2ccccc2c3nnc(SC(C)C)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H16 compound treatment 739827.0 269000.0 0.55 657287.0 188000.0 0.41 0.6795 0.9883 1779901 ChemDiv1_025514 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)cc5Cl)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H17 compound treatment 776933.0 306000.0 0.63 734294.0 265000.0 0.57 0.8515 0.9988 1981724 ChemDiv1_025515 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H18 compound treatment 707419.0 236000.0 0.49 668482.0 199000.0 0.43 0.6493 0.9981 1981725 ChemDiv1_025516 CCCCCC1(CCCCC)NN(C(=S)N1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H19 compound treatment 752372.0 281000.0 0.58 700355.0 231000.0 0.5 0.7637 0.9972 1981726 ChemDiv1_025517 CN(C)C1=NC(N=C(O1)c2ccc(F)cc2)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H20 compound treatment 725151.0 254000.0 0.52 693834.0 224000.0 0.49 0.714 0.9993 1239759 ChemDiv1_025518 CC1(C)OC(=O)N(CCC#N)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H21 compound treatment 758457.0 287000.0 0.59 715575.0 246000.0 0.53 0.7959 0.9986 1208506 ChemDiv1_025519 Cc1cccc(c1)C2(CC2C(=O)Nc3ccccc3F)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H22 compound treatment 728442.0 257000.0 0.53 709030.0 240000.0 0.52 0.7421 0.9999 1981727 ChemDiv1_025520 c1ccc(cc1)c2ccc(cc2)c3nc([nH]c3c4ccc(cc4)c5ccccc5)c6c7ccccc7cc8ccccc68 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H23 mock treatment 717037.0 246000.0 0.51 699036.0 230000.0 0.5 0.7101 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 H24 mock treatment 243728.0 -227000.0 -0.47 199809.0 -270000.0 -0.58 -0.7448 -0.9942 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I01 compound treatment 618475.0 147000.0 0.3 580416.0 111000.0 0.24 0.3847 0.9932 1429387 ChemDiv1_025521 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3cc(Br)c(O)c(Br)c3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I02 compound treatment 652965.0 182000.0 0.38 636508.0 167000.0 0.36 0.5209 0.9998 1981728 ChemDiv1_025522 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(OC)c(OC)c(OC)c2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I03 compound treatment 682306.0 211000.0 0.44 675544.0 206000.0 0.45 0.6235 0.9999 1981729 ChemDiv1_025523 [O-][N+](=O)c1ccc-2c(Cc3cccnc32)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I04 compound treatment 685174.0 214000.0 0.44 671969.0 202000.0 0.44 0.6222 1.0 1981730 ChemDiv1_025524 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccncc2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I05 compound treatment 708047.0 237000.0 0.49 692530.0 223000.0 0.48 0.6871 1.0 1981731 ChemDiv1_025525 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(O)cc(O)c2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I06 compound treatment 707082.0 236000.0 0.49 683859.0 214000.0 0.46 0.6724 0.9997 1981732 ChemDiv1_025526 Cc1ccccc1C2(CC2C(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I07 compound treatment 723130.0 252000.0 0.52 705010.0 236000.0 0.51 0.7282 1.0 1981733 ChemDiv1_025527 Cc1ccc(cc1)C(=O)N2CCN(C2)C(=O)CN3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I08 compound treatment 734389.0 263000.0 0.54 712343.0 243000.0 0.53 0.7558 0.9999 1981734 ChemDiv1_025528 Nc1nonc1n2nnc(C(=O)N/N=C/C=C/c3ccccc3)c2CN4CCCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I09 compound treatment 754861.0 284000.0 0.59 717336.0 248000.0 0.54 0.7934 0.999 1981735 ChemDiv1_025529 CCCS(=O)(=O)c1c(C(=O)N/N=C/C(C)C)n2ccccc2c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I10 compound treatment 740026.0 269000.0 0.55 717432.0 248000.0 0.54 0.7719 0.9999 1678862 ChemDiv1_025530 Cc1ccc(cc1)C2(CC2C(=O)Nc3ccc(I)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I11 compound treatment 754720.0 284000.0 0.59 702404.0 233000.0 0.5 0.7703 0.9972 1981736 ChemDiv1_025531 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(OC)c(OC)c(OC)c2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I12 compound treatment 737121.0 266000.0 0.55 663099.0 194000.0 0.42 0.6845 0.9911 1359998 ChemDiv1_025532 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C)c5ccccc5C3(C)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I13 compound treatment 747332.0 276000.0 0.57 715581.0 246000.0 0.53 0.7797 0.9994 1981737 ChemDiv1_025533 OC(=O)C1C2CC3C(OC(=O)C13)C2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I14 compound treatment 747801.0 277000.0 0.57 720065.0 251000.0 0.54 0.7872 0.9997 1981738 ChemDiv1_025534 CCN(CC)c1ccc(C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5)c(OCc6ccc(Cl)cc6)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I15 compound treatment 712180.0 241000.0 0.5 740264.0 271000.0 0.59 0.7662 0.9967 1981739 ChemDiv1_025535 CN(C)C1(CCCCC1)c2nnnn2c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I16 compound treatment 691463.0 220000.0 0.45 647462.0 178000.0 0.39 0.5939 0.9966 1981740 ChemDiv1_025536 CCOC(=O)C1(N=C(OC(=N1)c2ccc(F)cc2)N3CCCCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I17 compound treatment 771388.0 300000.0 0.62 721508.0 252000.0 0.55 0.8239 0.998 1981741 ChemDiv1_025537 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cc(O)cc(O)c2)n3cccc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I18 compound treatment 727952.0 257000.0 0.53 703397.0 234000.0 0.51 0.7328 0.9997 1981742 ChemDiv1_025538 Brc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I19 compound treatment 716516.0 245000.0 0.51 685861.0 216000.0 0.47 0.6892 0.9992 1521728 ChemDiv1_025539 CC(=O)Oc1ccc(c(OC(=O)C)c1)C2(C)CC(C)(C)NC(=S)N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I20 compound treatment 717229.0 246000.0 0.51 726840.0 257000.0 0.56 0.753 0.9989 1340543 ChemDiv1_025540 NC(=O)C1CCN(Cn2nc(c3ccccc3Cl)n(c4ccccc4)c2=S)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I21 compound treatment 747170.0 276000.0 0.57 745646.0 276000.0 0.6 0.8255 0.9997 1981743 ChemDiv1_025541 CCc1ccccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6[N+](=O)[O-])c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I22 compound treatment 948003.0 477000.0 0.98 884670.0 415000.0 0.9 1.3314 0.999 1981744 ChemDiv1_025542 O=C([C@H]1[C@H](c2cccnc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I23 mock treatment 703417.0 232000.0 0.48 689497.0 220000.0 0.48 0.6757 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 I24 mock treatment 222491.0 -249000.0 -0.51 172876.0 -297000.0 -0.64 -0.817 -0.9939 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J01 compound treatment 655906.0 185000.0 0.38 611189.0 142000.0 0.31 0.4865 0.9942 1981745 ChemDiv1_025543 CCOC(=O)C1(C)C=C(Nc2ccc(Br)cc2)C(=O)N1c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J02 compound treatment 661780.0 191000.0 0.39 652377.0 183000.0 0.4 0.5581 1.0 1779897 ChemDiv1_025544 CCc1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J03 compound treatment 693321.0 222000.0 0.46 701546.0 232000.0 0.5 0.6794 0.999 1981746 ChemDiv1_025545 CN1C(=S)SC(N2OC3C(C2c4cccc(c4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J04 compound treatment 692023.0 221000.0 0.46 683572.0 214000.0 0.46 0.65 1.0 1981747 ChemDiv1_025546 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5cccc(C)c5C)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J05 compound treatment 750103.0 279000.0 0.58 691448.0 222000.0 0.48 0.7468 0.996 1688771 ChemDiv1_025547 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(I)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J06 compound treatment 728893.0 258000.0 0.53 643726.0 174000.0 0.38 0.6428 0.9858 1981748 ChemDiv1_025548 CC(C)CC1C(=C(NC(=C1C(=O)C)C)SCc2cccc(c2)[N+](=O)[O-])C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J07 compound treatment 757492.0 286000.0 0.59 721320.0 252000.0 0.55 0.8033 0.9992 1981749 ChemDiv1_025549 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J08 compound treatment 745462.0 274000.0 0.57 721411.0 252000.0 0.55 0.7859 0.9998 1981750 ChemDiv1_025550 O=C1c2ccccc2-c3ccc(cc13)c4nc([nH]c4c5ccccc5)c6ccc(C#Cc7ccccc7)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J09 compound treatment 757468.0 286000.0 0.59 742520.0 273000.0 0.59 0.8357 1.0 1981751 ChemDiv1_025551 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J10 compound treatment 729013.0 258000.0 0.53 700533.0 231000.0 0.5 0.7299 0.9995 1120922 ChemDiv1_025552 COc1ccc(OC)c(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J11 compound treatment 760788.0 290000.0 0.6 762297.0 293000.0 0.63 0.8708 0.9996 1981752 ChemDiv1_025553 COc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(Cl)c3)/C42CCC(C)CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J12 compound treatment 742064.0 271000.0 0.56 718805.0 249000.0 0.54 0.7769 0.9998 1370410 ChemDiv1_025554 CCC1(CC(NC(=S)N1)c2ccccc2)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J13 compound treatment 757445.0 286000.0 0.59 722622.0 253000.0 0.55 0.8052 0.9993 1981753 ChemDiv1_025555 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J14 compound treatment 747112.0 276000.0 0.57 665908.0 196000.0 0.43 0.7033 0.9896 1981754 ChemDiv1_025556 Clc1ccc2N=C(NN=C(c3ccccc3)c2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J15 compound treatment 716920.0 246000.0 0.51 738570.0 269000.0 0.58 0.7705 0.9976 1981755 ChemDiv1_025557 CCCSc1nnc2c3ccccc3n(CCC)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J16 compound treatment 774875.0 304000.0 0.63 738774.0 269000.0 0.58 0.8554 0.9993 1124317 ChemDiv1_025558 OCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(I)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J17 compound treatment 935116.0 464000.0 0.96 960592.0 491000.0 1.06 1.4288 0.9986 1981756 ChemDiv1_025559 CC(=O)C1=NN(C(N1c2ccc(Cl)cc2)c3cccs3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J18 compound treatment 766749.0 296000.0 0.61 725031.0 256000.0 0.55 0.8225 0.9988 1945725 ChemDiv1_025560 CN1CCN(CC1)C2=NC(=O)/C(=C/c3ccc(Cl)cc3)/S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J19 compound treatment 765441.0 294000.0 0.61 748114.0 279000.0 0.6 0.8559 1.0 1398481 ChemDiv1_025561 Cc1ccc(cc1)N2NC3(CCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J20 compound treatment 757807.0 287000.0 0.59 722059.0 253000.0 0.55 0.8049 0.9992 1981757 ChemDiv1_025562 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4ccc(Cl)c(Cl)c4NC3c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J21 compound treatment 755868.0 285000.0 0.59 647775.0 178000.0 0.39 0.6884 0.9792 1651831 ChemDiv1_025563 Clc1cccc(Cl)c1NC(=O)C2CC2(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J22 compound treatment 760117.0 289000.0 0.6 718104.0 249000.0 0.54 0.8022 0.9987 1981758 ChemDiv1_025564 COc1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)c4ccccc4)c5ccc(cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J23 mock treatment 729068.0 258000.0 0.53 708567.0 239000.0 0.52 0.7423 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 J24 mock treatment 242900.0 -228000.0 -0.47 240963.0 -229000.0 -0.49 -0.683 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K01 compound treatment 635674.0 164000.0 0.34 574387.0 105000.0 0.23 0.4006 0.9809 1311803 ChemDiv1_025565 Cc1ccc2ccc(cc2c1)S(=O)(=O)n3nnc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K02 compound treatment 630912.0 160000.0 0.33 631110.0 162000.0 0.35 0.4805 0.9996 1277592 ChemDiv1_025566 O=C(Oc1ccccc1)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K03 compound treatment 670009.0 199000.0 0.41 662935.0 193000.0 0.42 0.5862 0.9999 1981759 ChemDiv1_025567 Cc1cnc-2c(c1)/C(=N\c3cccc4ccccc34)/c5cccc(C)c52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K04 compound treatment 678765.0 208000.0 0.43 661907.0 192000.0 0.42 0.5975 0.9999 1458812 ChemDiv1_025568 CC(C)Oc1ccccc1C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K05 compound treatment 714193.0 243000.0 0.5 705170.0 236000.0 0.51 0.7154 1.0 1981760 ChemDiv1_025569 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2c[nH]c3ccccc23)n4ccc(cc4c1S(=O)(=O)CCC)c5ccncc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K06 compound treatment 691106.0 220000.0 0.45 676629.0 207000.0 0.45 0.638 1.0 1195392 ChemDiv1_025570 CC(=O)OCC1OC(C(OC(=O)C)C1OC(=O)C)n2ccc(O)nc2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K07 compound treatment 733742.0 263000.0 0.54 695093.0 226000.0 0.49 0.7285 0.9986 1981761 ChemDiv1_025571 Cc1c(/N=C/c2cccc3ccccc23)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K08 compound treatment 727107.0 256000.0 0.53 704686.0 235000.0 0.51 0.7335 0.9998 1981762 ChemDiv1_025572 CC(/C=N/NC(=O)c1nnn(c1CN2CCCCCC2)c3nonc3N)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K09 compound treatment 741858.0 271000.0 0.56 714220.0 245000.0 0.53 0.7696 0.9996 1981763 ChemDiv1_025573 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(cc2)[N+](=O)[O-])n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K10 compound treatment 727859.0 257000.0 0.53 700411.0 231000.0 0.5 0.728 0.9996 1372447 ChemDiv1_025574 Cc1cccc(c1)C2(CC2C(=O)Nc3ccc(I)cc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K11 compound treatment 719594.0 248000.0 0.51 689270.0 220000.0 0.48 0.6989 0.9993 1981764 ChemDiv1_025575 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(c2)[N+](=O)[O-])n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K12 compound treatment 789822.0 319000.0 0.66 750792.0 281000.0 0.61 0.8956 0.9993 1981765 ChemDiv1_025576 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc3ccccc23)n4ccc5ccccc5c4c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K13 compound treatment 736779.0 266000.0 0.55 713449.0 244000.0 0.53 0.761 0.9998 1981766 ChemDiv1_025577 [O-][N+](=O)c1ccccc1C(=O)N/N=C/c2ccc(Sc3nnc(c4ccccc4)n3c5ccccc5)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K14 compound treatment 714548.0 243000.0 0.5 695690.0 226000.0 0.49 0.7014 0.9999 1981767 ChemDiv1_025578 CC1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K15 compound treatment 778997.0 308000.0 0.64 725293.0 256000.0 0.55 0.8408 0.9976 1981768 ChemDiv1_025579 Cc1cccc(/N=C/2\NC(=S)N(c3cccc(C)c3)C42CCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K16 compound treatment 718982.0 248000.0 0.51 687199.0 218000.0 0.47 0.6949 0.9992 1981769 ChemDiv1_025580 Cc1ccc(c(C)c1)c2cnc3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K17 compound treatment 770280.0 299000.0 0.62 745445.0 276000.0 0.6 0.8589 0.9999 1981770 ChemDiv1_025581 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(OC)c2)n3cccc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K18 compound treatment 751675.0 280000.0 0.58 671413.0 202000.0 0.44 0.7184 0.9904 1981771 ChemDiv1_025582 CCCC1Oc2ccc(cc2C3OC(c4ccccc4)(c5ccccc5)c6ccccc6N13)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K19 compound treatment 743326.0 272000.0 0.56 727496.0 258000.0 0.56 0.7921 1.0 1981772 ChemDiv1_025583 Cc1cccc(Nc2nc3nonc3[nH]c2=N/N=C\c4cn(Cc5ccc(Cl)cc5Cl)c6ccccc46)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K20 compound treatment 724694.0 253000.0 0.52 704826.0 235000.0 0.51 0.7302 0.9999 1499087 ChemDiv1_025584 CC1CCN(Cn2nc(c3ccc(cc3)C(C)(C)C)n(c4ccccc4)c2=S)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K21 compound treatment 753824.0 283000.0 0.58 730818.0 261000.0 0.57 0.8125 0.9999 1981773 ChemDiv1_025585 O=C(Cc1cccc2ccccc12)Nc3cc4C5CCCC5CN6CC7CCCC7c(c3)c64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K22 compound treatment 721892.0 251000.0 0.52 701868.0 232000.0 0.5 0.7216 0.9999 1981774 ChemDiv1_025586 CC(=O)C1=C(C)NC(=C(C#N)[C@@H]1c2ccccc2[N+](=O)[O-])SCc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K23 mock treatment 708291.0 237000.0 0.49 700410.0 231000.0 0.5 0.6995 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 K24 mock treatment 286682.0 -185000.0 -0.38 221224.0 -248000.0 -0.54 -0.6493 -0.9858 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L01 compound treatment 640152.0 169000.0 0.35 601761.0 132000.0 0.29 0.449 0.9952 1981775 ChemDiv1_025587 Clc1cccc(c1)n2nnnc2C3(CCCCC3)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L02 compound treatment 664813.0 194000.0 0.4 665101.0 196000.0 0.42 0.582 0.9996 1981776 ChemDiv1_025588 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(cc5)C(=O)C)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L03 compound treatment 704259.0 233000.0 0.48 707901.0 238000.0 0.52 0.7051 0.9994 1981777 ChemDiv1_025589 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OCc5ccc(C)cc5)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L04 compound treatment 707736.0 237000.0 0.49 692878.0 223000.0 0.48 0.6871 1.0 1981778 ChemDiv1_025590 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5cc(C)ccc5C)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L05 compound treatment 763927.0 293000.0 0.6 732055.0 263000.0 0.57 0.8291 0.9995 1516118 ChemDiv1_025591 CCOC(=O)c1cccc(c1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L06 compound treatment 719142.0 248000.0 0.51 673873.0 204000.0 0.44 0.6747 0.9974 1981779 ChemDiv1_025592 CC(=O)C1SC(=C(C#N)C1c2ccc(Cl)c(Cl)c2)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L07 compound treatment 916589.0 445000.0 0.92 877885.0 408000.0 0.88 1.2751 0.9998 1351025 ChemDiv1_025593 CC(C)(C)OC(=O)N1CC=C2C(C1)C(c3ccsc3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L08 compound treatment 750039.0 279000.0 0.58 712138.0 243000.0 0.53 0.7784 0.999 1160840 ChemDiv1_025594 COc1ccc(c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L09 compound treatment 739391.0 268000.0 0.55 711760.0 242000.0 0.52 0.7622 0.9996 1981780 ChemDiv1_025595 CC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L10 compound treatment 726773.0 256000.0 0.53 697682.0 228000.0 0.49 0.7223 0.9995 1665730 ChemDiv1_025596 CC(=O)Oc1ccc2c(OC(CC32CC(C)(C)NC(=S)N3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L11 compound treatment 748410.0 277000.0 0.57 733557.0 264000.0 0.57 0.8088 1.0 1273530 ChemDiv1_025597 CC1(C)CC(C)(N(C(=S)N1)c2cccc(Cl)c2)c3ccc(O)cc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L12 compound treatment 738678.0 267000.0 0.55 719722.0 250000.0 0.54 0.7734 1.0 1981781 ChemDiv1_025598 CC(C)C1CCC(C)CC1OC(=O)c2cccc(c2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L13 compound treatment 758868.0 288000.0 0.59 730658.0 261000.0 0.57 0.8196 0.9997 1442081 ChemDiv1_025599 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(C)c5C)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L14 compound treatment 752320.0 281000.0 0.58 630067.0 161000.0 0.35 0.6561 0.97 1981782 ChemDiv1_025600 C(Cn1c(csc1=Nc2ccccc2)c3ccc(cc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L15 compound treatment 767071.0 296000.0 0.61 742274.0 273000.0 0.59 0.8494 0.9999 1981783 ChemDiv1_025601 CCCn1c2ccccc2c3nnc(S)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L16 compound treatment 698107.0 227000.0 0.47 714722.0 245000.0 0.53 0.7065 0.9981 1186452 ChemDiv1_025602 COc1ccc(cc1F)c2csc(=Nc3ccc(F)cc3)n2CCc4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L17 compound treatment 776252.0 305000.0 0.63 750727.0 281000.0 0.61 0.8757 0.9999 1981784 ChemDiv1_025603 COc1ccc(NC2=CC(N(C2=O)c3ccc(OC)cc3)c4cccc(OC)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L18 compound treatment 753765.0 283000.0 0.58 736153.0 267000.0 0.58 0.8206 1.0 1257291 ChemDiv1_025604 CCCS(=O)(=O)c1c(C(=O)c2ccc(Br)cc2)n3cc(C)cc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L19 compound treatment 753423.0 282000.0 0.58 776996.0 308000.0 0.67 0.8826 0.9978 1981785 ChemDiv1_025605 COc1ccc(cc1)c2oc(/N=C/c3ccc(cc3)N(C)C)c(C#N)c2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L20 compound treatment 748219.0 277000.0 0.57 664735.0 195000.0 0.42 0.7032 0.9889 1981786 ChemDiv1_025606 Cc1ccc(cc1)C(=O)OCC2OC(C(OC(=O)c3ccc(C)cc3)C2OC(=O)c4ccc(C)cc4)n5cc(C)c(=O)[nH]c5=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L21 compound treatment 766067.0 295000.0 0.61 759023.0 290000.0 0.63 0.8735 0.9999 1557044 ChemDiv1_025607 Oc1cccc(c1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L22 compound treatment 735290.0 264000.0 0.55 726899.0 257000.0 0.56 0.7794 0.9999 1258693 ChemDiv1_025608 O(c1ccccc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L23 mock treatment 712922.0 242000.0 0.5 734489.0 265000.0 0.57 0.7584 0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 L24 mock treatment 225559.0 -246000.0 -0.51 196197.0 -273000.0 -0.59 -0.7768 -0.9971 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M01 compound treatment 626261.0 155000.0 0.32 596623.0 127000.0 0.28 0.4209 0.9972 1935672 ChemDiv1_025609 Brc1ccc(c(Br)c1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M02 compound treatment 691781.0 221000.0 0.46 680925.0 211000.0 0.46 0.6456 1.0 1981787 ChemDiv1_025610 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccccc2)c3ccccc3[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M03 compound treatment 642911.0 172000.0 0.35 611452.0 142000.0 0.31 0.4679 0.9975 1981788 ChemDiv1_025611 Cc1ccnc2-c3ccccc3/C(=N/c4ccccc4)/c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M04 compound treatment 665385.0 194000.0 0.4 661509.0 192000.0 0.42 0.5773 0.9998 1541835 ChemDiv1_025612 CCOc1ccc(cc1OC)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M05 compound treatment 684533.0 213000.0 0.44 703202.0 234000.0 0.51 0.6691 0.9976 1981789 ChemDiv1_025613 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccncc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M06 compound treatment 678183.0 207000.0 0.43 648302.0 179000.0 0.39 0.5758 0.9988 1102519 ChemDiv1_025614 S=C1NC2(CCCCCC2)NN1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M07 compound treatment 722226.0 251000.0 0.52 686392.0 217000.0 0.47 0.6984 0.9988 1321685 ChemDiv1_025615 Cc1cccc(C)c1NC(=O)C2(CCC(CC2)C(C)(C)C)N(Cc3ccccc3)C(=O)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M08 compound treatment 708260.0 237000.0 0.49 668570.0 199000.0 0.43 0.6507 0.998 1981790 ChemDiv1_025616 C/C(=N\NC(=O)c1nnn(c1CN2CCCCCC2)c3nonc3N)/c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M09 compound treatment 763376.0 292000.0 0.6 707990.0 239000.0 0.52 0.7915 0.997 1981791 ChemDiv1_025617 CCOC(=O)C1(C)C=C(Nc2ccc(cc2)C(=O)C)C(=O)N1c3ccc(cc3)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M10 compound treatment 690761.0 220000.0 0.45 676471.0 207000.0 0.45 0.6373 1.0 1981792 ChemDiv1_025618 Clc1ccc(Cl)c(c1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M11 compound treatment 742041.0 271000.0 0.56 707792.0 238000.0 0.52 0.76 0.9992 1981793 ChemDiv1_025619 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)c(OC)c2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M12 compound treatment 718533.0 247000.0 0.51 687111.0 218000.0 0.47 0.6941 0.9992 1981794 ChemDiv1_025620 CCCS(=O)(=O)c1c(C(=O)N/N=C/C(C)C)n2ccc3ccccc3c2c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M13 compound treatment 733501.0 262000.0 0.54 695450.0 226000.0 0.49 0.7287 0.9987 1981795 ChemDiv1_025621 Cc1cccc(/N=C/2\NC(=S)N(c3ccccc3C)C42CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M14 compound treatment 725245.0 254000.0 0.52 713565.0 244000.0 0.53 0.7444 1.0 1981796 ChemDiv1_025622 COc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6cccc7ccccc67)c8ccccc48)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M15 compound treatment 754756.0 284000.0 0.59 696463.0 227000.0 0.49 0.7613 0.9962 1981797 ChemDiv1_025623 CC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M16 compound treatment 729261.0 258000.0 0.53 667137.0 198000.0 0.43 0.6792 0.9941 1981798 ChemDiv1_025624 CC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M17 compound treatment 748754.0 278000.0 0.57 710570.0 241000.0 0.52 0.7741 0.9989 1981799 ChemDiv1_025625 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(OC)c2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M18 compound treatment 885628.0 414000.0 0.86 907966.0 438000.0 0.95 1.276 0.9987 1639159 ChemDiv1_025626 COc1ccccc1C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M19 compound treatment 752860.0 282000.0 0.58 702624.0 233000.0 0.5 0.7679 0.9975 1981800 ChemDiv1_025627 CCN(CC)Cc1c(nnn1c2nonc2N)C(=O)N/N=C/CCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M20 compound treatment 727979.0 257000.0 0.53 673699.0 204000.0 0.44 0.6873 0.9959 1981801 ChemDiv1_025628 CCOC(=O)C1=NN(c2ccc(C)cc2)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M21 compound treatment 750197.0 279000.0 0.58 710826.0 241000.0 0.52 0.7766 0.9988 1779215 ChemDiv1_025629 Oc1c(cc(cc1c2nc(c([nH]2)c3ccccc3)c4ccccc4)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M22 compound treatment 714473.0 243000.0 0.5 695033.0 226000.0 0.49 0.7003 0.9999 1712557 ChemDiv1_025630 COC(=O)C1=C(N)n2c(=O)c(=Cc3ccccc3OC)sc2=C(C1c4ccccc4OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M23 mock treatment 708167.0 237000.0 0.49 684893.0 215000.0 0.47 0.6756 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 M24 mock treatment 194867.0 -276000.0 -0.57 370330.0 -99200.0 -0.21 -0.5551 -0.9108 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N01 compound treatment 630582.0 159000.0 0.33 612699.0 143000.0 0.31 0.4518 0.9996 1981802 ChemDiv1_025631 CC1CCC/2(CC1)N(CC#N)C(=S)N\C2=N/c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N02 compound treatment 670093.0 199000.0 0.41 660657.0 191000.0 0.41 0.5829 1.0 1981803 ChemDiv1_025632 Cc1cccc(c1)N2C(=O)C3C(C(CCC3c4ccccc4)c5ccccc5)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N03 compound treatment 681300.0 210000.0 0.43 659533.0 190000.0 0.41 0.5975 0.9997 1981804 ChemDiv1_025633 CCCCCCCOc1ccc(cc1)C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N04 compound treatment 693650.0 222000.0 0.46 681728.0 212000.0 0.46 0.6495 1.0 1981805 ChemDiv1_025634 Clc1cccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6Cl)c7ccccc47)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N05 compound treatment 701719.0 231000.0 0.48 642522.0 173000.0 0.37 0.6013 0.993 1981806 ChemDiv1_025635 CC1(C)CC(C)(N(C(=S)N1)c2ccccc2)c3ccc(OC(=O)c4ccccc4)cc3OC(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N06 compound treatment 684145.0 213000.0 0.44 635812.0 166000.0 0.36 0.5654 0.9951 1981807 ChemDiv1_025636 Cc1ccccc1[C@H]2[C@@H](SC(=C2C#N)N)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N07 compound treatment 924199.0 453000.0 0.94 934374.0 465000.0 1.01 1.3727 0.9993 1981808 ChemDiv1_025637 CC(C)(C)OC(=O)N1CC=C2C(C1)C(c3ccoc3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N08 compound treatment 709019.0 238000.0 0.49 683583.0 214000.0 0.46 0.6748 0.9996 1399416 ChemDiv1_025638 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4cc(OC)cc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N09 compound treatment 774651.0 303000.0 0.63 766188.0 297000.0 0.64 0.897 0.9999 1718347 ChemDiv1_025639 CN1C2CCC1C3C(c4ccccc4F)C(C#N)(C#N)C(=C(C#N)C3=C2)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N10 compound treatment 720103.0 249000.0 0.51 689817.0 220000.0 0.48 0.7005 0.9993 1981809 ChemDiv1_025640 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N11 compound treatment 743206.0 272000.0 0.56 723412.0 254000.0 0.55 0.7857 0.9999 1343913 ChemDiv1_025641 CC1(C)Cc2ccccc2C(=C(C#N)C#N)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N12 compound treatment 728997.0 258000.0 0.53 695449.0 226000.0 0.49 0.7221 0.9991 1981810 ChemDiv1_025642 O=C(OCc1ccccc1)c2ccc(cc2)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N13 compound treatment 732978.0 262000.0 0.54 664766.0 195000.0 0.42 0.681 0.9926 1981811 ChemDiv1_025643 CC1(C)OC(=O)N(CC=C)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N14 compound treatment 726544.0 255000.0 0.53 703177.0 234000.0 0.51 0.7304 0.9998 1981812 ChemDiv1_025644 Fc1ccc(N=c2scc(c3ccc(cc3)c4ccccc4)n2CCc5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N15 compound treatment 733719.0 263000.0 0.54 745261.0 276000.0 0.6 0.8052 0.9988 1566822 ChemDiv1_025645 Clc1ccc(cc1)C(=O)NC2(CCCCC2)C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N16 compound treatment 710618.0 239000.0 0.49 706260.0 237000.0 0.51 0.7118 0.9998 1981813 ChemDiv1_025646 CCc1ccccc1N2C(=O)C3C(C(CCC3c4ccccc4)c5ccccc5)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N17 compound treatment 762798.0 292000.0 0.6 730050.0 261000.0 0.56 0.8244 0.9995 1331936 ChemDiv1_025647 CC1CCN(C(C)C1)C(=O)CSc2nnc3c4ccccc4[nH]c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N18 compound treatment 736524.0 265000.0 0.55 693894.0 224000.0 0.49 0.7307 0.9982 1981814 ChemDiv1_025648 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc5ccccc5c4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N19 compound treatment 756667.0 285000.0 0.59 732466.0 263000.0 0.57 0.8192 0.9998 1981815 ChemDiv1_025649 COc1ccc(cc1)c2oc(/N=C/c3ccc(cc3)[N+](=O)[O-])c(C#N)c2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N20 compound treatment 728408.0 257000.0 0.53 660996.0 192000.0 0.41 0.6685 0.9925 1981816 ChemDiv1_025650 CC1(C)c2ccccc2N3CC(=O)NC31/C=C/c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N21 compound treatment 752677.0 281000.0 0.58 705598.0 236000.0 0.51 0.7722 0.998 1981817 ChemDiv1_025651 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccc(OC)cc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N22 compound treatment 737194.0 266000.0 0.55 689556.0 220000.0 0.48 0.7251 0.9975 1981818 ChemDiv1_025652 COc1cccc(c1)c2nc(c([nH]2)c3ccc(cc3)c4ccccc4)c5ccc(cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N23 mock treatment 737537.0 266000.0 0.55 699031.0 230000.0 0.5 0.7401 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 N24 mock treatment 209035.0 -262000.0 -0.54 370246.0 -99200.0 -0.21 -0.5346 -0.9181 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O01 compound treatment 620519.0 149000.0 0.31 583235.0 114000.0 0.25 0.392 0.9938 1625084 ChemDiv1_025653 COc1cc(ccc1OCC=C)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O02 compound treatment 641386.0 170000.0 0.35 604554.0 135000.0 0.29 0.4551 0.9958 1981819 ChemDiv1_025654 CCCCOc1ccc(cc1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O03 compound treatment 649807.0 179000.0 0.37 597222.0 128000.0 0.28 0.4562 0.9899 1920531 ChemDiv1_025655 COc1ccc(/C=C\2/c3ccc(C)cc3-c4nc5ccccc5cc24)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O04 compound treatment 651355.0 180000.0 0.37 621686.0 152000.0 0.33 0.4959 0.9982 1981820 ChemDiv1_025656 ClC(Cl)(Cl)C1=Nc2ccccc2C(O1)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O05 compound treatment 682070.0 211000.0 0.44 678369.0 209000.0 0.45 0.6275 0.9998 1981821 ChemDiv1_025657 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2ccccc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O06 compound treatment 657927.0 187000.0 0.39 628267.0 159000.0 0.34 0.5156 0.9984 1981822 ChemDiv1_025658 CCCC1(CCC)NN(C(=S)N1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O07 compound treatment 703008.0 232000.0 0.48 664181.0 195000.0 0.42 0.6363 0.998 1981823 ChemDiv1_025659 CC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)N(N=C(c4ccc(Br)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O08 compound treatment 718292.0 247000.0 0.51 653397.0 184000.0 0.4 0.6421 0.9925 1981824 ChemDiv1_025660 CCC(N1CCCCC1)C2=Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O09 compound treatment 722026.0 251000.0 0.52 675412.0 206000.0 0.45 0.6813 0.9972 1981825 ChemDiv1_025661 Cc1c(Cl)cccc1/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6[N+](=O)[O-])c7ccccc47 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O10 compound treatment 677336.0 206000.0 0.43 660133.0 191000.0 0.41 0.5927 0.9999 1981826 ChemDiv1_025662 CCCCOc1ccc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O11 compound treatment 749899.0 279000.0 0.58 724520.0 255000.0 0.55 0.7971 0.9998 1408696 ChemDiv1_025663 Nc1cc2C(CCN3CCC(c4ccccc4)c(c1)c32)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O12 compound treatment 696332.0 225000.0 0.46 653177.0 184000.0 0.4 0.6097 0.997 1981827 ChemDiv1_025664 COc1cc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O13 compound treatment 703366.0 232000.0 0.48 673451.0 204000.0 0.44 0.651 0.9992 1981828 ChemDiv1_025665 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCCC3)N1c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O14 compound treatment 720017.0 249000.0 0.51 639897.0 170000.0 0.37 0.624 0.9868 1981829 ChemDiv1_025666 COc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N\c5ccccc5C)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O15 compound treatment 739045.0 268000.0 0.55 673911.0 204000.0 0.44 0.7038 0.9939 1981830 ChemDiv1_025667 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(F)c2)n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O16 compound treatment 688518.0 217000.0 0.45 654049.0 185000.0 0.4 0.5997 0.9983 1981831 ChemDiv1_025668 CC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O17 compound treatment 727425.0 256000.0 0.53 687081.0 218000.0 0.47 0.707 0.9983 1213312 ChemDiv1_025669 COc1ccc2n(C)c(CC(=O)Nc3ccc(C)cc3)c(Sc4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O18 compound treatment 690330.0 219000.0 0.45 655123.0 186000.0 0.4 0.604 0.9983 1252250 ChemDiv1_025670 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3cccc(O)c3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O19 compound treatment 719030.0 248000.0 0.51 699375.0 230000.0 0.5 0.7136 0.9999 1981832 ChemDiv1_025671 CN1CCN(CC1)c2cc(N3CCN(C)CC3)c(cc2C4Nc5ccc6ccccc6c5C7=C4C(=O)CC(C)(C)C7)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O20 compound treatment 678583.0 207000.0 0.43 651492.0 182000.0 0.39 0.5813 0.9991 1705376 ChemDiv1_025672 Cc1ccc(cc1)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O21 compound treatment 902895.0 432000.0 0.89 816843.0 347000.0 0.75 1.1617 0.9964 1981833 ChemDiv1_025673 COC(=O)c1cccc(c1)N2C(=O)/C(=C/c3ccc(Br)cc3)/C=C2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O22 compound treatment 703095.0 232000.0 0.48 666207.0 197000.0 0.43 0.6396 0.9983 1474007 ChemDiv1_025674 CCOC(=O)C1=c2sc(=Cc3ccccc3OC)c(=O)n2C(=C(C1c4ccccc4OC)C(=O)OC)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O23 mock treatment 696332.0 225000.0 0.46 649786.0 180000.0 0.39 0.6045 0.9962 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 O24 mock treatment 404217.0 -67000.0 -0.14 270755.0 -199000.0 -0.43 -0.4019 -0.8896 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P01 compound treatment 623288.0 152000.0 0.31 579046.0 110000.0 0.24 0.3897 0.9904 1981834 ChemDiv1_025675 Clc1cccc(c1)n2nnnc2C3(CCCCC3)NC=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P02 compound treatment 641322.0 170000.0 0.35 591141.0 122000.0 0.26 0.4345 0.9899 1981835 ChemDiv1_025676 Cc1cc(ccc1S(=O)(=O)n2nnc3ccccc23)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P03 compound treatment 613135.0 142000.0 0.29 608143.0 139000.0 0.3 0.4194 0.9999 1981836 ChemDiv1_025677 CCCS(=O)(=O)c1c(C(=O)N/N=C/c2cccc(F)c2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P04 compound treatment 657372.0 186000.0 0.38 607917.0 138000.0 0.3 0.4836 0.9924 1637607 ChemDiv1_025678 COc1ccc(C2N(Cc3ccccc3)CCN2Cc4ccccc4)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P05 compound treatment 654323.0 183000.0 0.38 630154.0 161000.0 0.35 0.5132 0.9991 1981837 ChemDiv1_025679 CCc1ccc(/N=C\C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccc(OC)cc6)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P06 compound treatment 662212.0 191000.0 0.39 606293.0 137000.0 0.3 0.4882 0.99 1981838 ChemDiv1_025680 CC(C)N1CC(C)C(CC1C)(OC(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P07 compound treatment 827014.0 356000.0 0.73 695554.0 226000.0 0.49 0.8653 0.9805 1981839 ChemDiv1_025681 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P08 compound treatment 666451.0 195000.0 0.4 624592.0 155000.0 0.34 0.5224 0.9959 1271372 ChemDiv1_025682 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4ccc(OC)cc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P09 compound treatment 701949.0 231000.0 0.48 637821.0 168000.0 0.36 0.5944 0.9912 1981840 ChemDiv1_025683 OC(=O)c1ccc2NC(C3CC(Sc4ccccc4[N+](=O)[O-])C(Cl)C3c2c1)c5ccccc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P10 compound treatment 664181.0 193000.0 0.4 633342.0 164000.0 0.35 0.5325 0.9983 1981841 ChemDiv1_025684 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)N(N=C(c4ccccc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P11 compound treatment 694379.0 223000.0 0.46 632139.0 163000.0 0.35 0.5747 0.9912 1184254 ChemDiv1_025685 COc1ccc(NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P12 compound treatment 688066.0 217000.0 0.45 642073.0 173000.0 0.37 0.5807 0.996 1481008 ChemDiv1_025686 O=C(CN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)OC6CCCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P13 compound treatment 662098.0 191000.0 0.39 627580.0 158000.0 0.34 0.5206 0.9975 1345018 ChemDiv1_025687 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3)c4ccc(cc4)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P14 compound treatment 656058.0 185000.0 0.38 631035.0 162000.0 0.35 0.5171 0.999 1981842 ChemDiv1_025688 Cc1cc(Cl)cc2C(=NNC(=Nc12)c3ccc(Br)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P15 compound treatment 662335.0 191000.0 0.39 633467.0 164000.0 0.35 0.5299 0.9986 1981843 ChemDiv1_025689 CCOC(=O)c1ccc(/N=C/2\NC3(CCCCC3)Cc4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P16 compound treatment 693022.0 222000.0 0.46 665105.0 196000.0 0.42 0.6232 0.9992 1294613 ChemDiv1_025690 COc1ccccc1C(=O)Nc2cc3C4CCCC4CN5CC6CCCC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P17 compound treatment 682070.0 211000.0 0.44 639215.0 170000.0 0.37 0.5676 0.9964 1146386 ChemDiv1_025691 COc1ccc(CCNC(=O)CSc2nnc3c4ccccc4[nH]c3n2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P18 compound treatment 675175.0 204000.0 0.42 650679.0 181000.0 0.39 0.575 0.9994 1981844 ChemDiv1_025692 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc(Cl)cc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P19 compound treatment 673394.0 202000.0 0.42 656697.0 187000.0 0.41 0.5816 0.9999 1981845 ChemDiv1_025693 CC(C)c1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(C)cc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P20 compound treatment 664433.0 193000.0 0.4 645112.0 176000.0 0.38 0.5508 0.9997 1243797 ChemDiv1_025694 CNC(=O)CN1c2ccccc2C(C)(C)C31Oc4ccc5ccccc5c4C=C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P21 compound treatment 665220.0 194000.0 0.4 637261.0 168000.0 0.36 0.54 0.9988 1981846 ChemDiv1_025695 [O-][N+](=O)c1ccc(cc1)C2N(N=C(N2c3ccc(cc3)N4CCOCC4)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P22 compound treatment 684159.0 213000.0 0.44 619483.0 150000.0 0.32 0.5404 0.9889 1981847 ChemDiv1_025696 Cc1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)c4ccccc4)c5ccc(cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P23 mock treatment 652756.0 182000.0 0.37 632334.0 163000.0 0.35 0.5142 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.659 P24 mock treatment 259739.0 -211000.0 -0.44 459109.0 -10400.0 -0.02 -0.3246 -0.7425 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A01 compound treatment 624850.0 141000.0 0.29 583070.0 114000.0 0.25 0.3795 0.9966 1981848 ChemDiv1_025697 c1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)c4ccccc4)c5ccc(cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A02 compound treatment 607511.0 123000.0 0.25 587131.0 118000.0 0.26 0.3604 1.0 1981849 ChemDiv1_025698 Cc1cccc(c1)C(O)(C(=O)NN(C(=O)c2cccnc2Cl)c3ccccc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A03 compound treatment 622753.0 139000.0 0.29 599179.0 130000.0 0.28 0.4011 1.0 1981850 ChemDiv1_025699 CC(=O)C1=NN(c2ccccc2C)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A04 compound treatment 628283.0 144000.0 0.3 598017.0 129000.0 0.28 0.4074 0.9995 1686736 ChemDiv1_025700 Cc1ccc(cc1)N2NC3(CCCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A05 compound treatment 654789.0 171000.0 0.35 613723.0 144000.0 0.31 0.4701 0.9982 1981851 ChemDiv1_025701 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A06 compound treatment 657529.0 173000.0 0.36 629418.0 160000.0 0.35 0.4981 0.9999 1389828 ChemDiv1_025702 O=C1CC(C2COC1O2)n3nc(COc4ccccc4)n(c5ccccc5)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A07 compound treatment 673611.0 189000.0 0.39 645919.0 177000.0 0.38 0.5469 0.9999 1981852 ChemDiv1_025703 CCOC(=O)c1ccc(NC2=CC(C)(N(C2=O)c3ccccc3)C(=O)OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A08 compound treatment 654394.0 170000.0 0.35 646750.0 177000.0 0.38 0.5201 0.999 1981853 ChemDiv1_025704 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccc(cc3)[N+](=O)[O-])c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A09 compound treatment 666899.0 183000.0 0.38 645233.0 176000.0 0.38 0.536 1.0 1604643 ChemDiv1_025705 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccc(Cl)cc3)O)c4ccc(Br)cn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A10 compound treatment 649991.0 166000.0 0.34 641608.0 172000.0 0.37 0.5058 0.9991 1981854 ChemDiv1_025706 Fc1ccc(cc1)c2nc3c([nH]2)c4cc(I)ccc4c5ccc(I)cc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A11 compound treatment 642594.0 158000.0 0.33 635243.0 166000.0 0.36 0.4852 0.9989 1981855 ChemDiv1_025707 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A12 compound treatment 741037.0 257000.0 0.53 686519.0 217000.0 0.47 0.7074 0.9982 1246710 ChemDiv1_025708 N#CC(=C1NC2(CCCC2)Cc3ccccc13)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A13 compound treatment 689778.0 206000.0 0.42 648759.0 179000.0 0.39 0.5748 0.999 1464213 ChemDiv1_025709 OC1=C(C(N(C1=O)c2ccccn2)c3ccccc3)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A14 compound treatment 672530.0 188000.0 0.39 648846.0 180000.0 0.39 0.5498 1.0 1924671 ChemDiv1_025710 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(c5)C(=O)O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A15 compound treatment 662348.0 178000.0 0.37 652275.0 183000.0 0.4 0.5401 0.9993 1981856 ChemDiv1_025711 FC(F)(F)c1cccc(c1)N2C(=S)N/C(=N\c3ccccc3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A16 compound treatment 667013.0 183000.0 0.38 668191.0 199000.0 0.43 0.5713 0.9978 1475708 ChemDiv1_025712 NC(=O)C1C2CCCC1C2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A17 compound treatment 680977.0 197000.0 0.41 663888.0 195000.0 0.42 0.5851 0.9998 1981857 ChemDiv1_025713 CC1(C2C(C(=O)N(C2=O)c3ccc(Cl)c(c3)C(F)(F)F)C4(C=O)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A18 compound treatment 653424.0 169000.0 0.35 640195.0 171000.0 0.37 0.5086 0.9996 1981858 ChemDiv1_025714 CCN1/C(=C\2/SC(=S)N(Cc3ccccc3)C2=O)/Sc4ccc(Cl)cc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A19 compound treatment 689753.0 206000.0 0.42 641297.0 172000.0 0.37 0.5633 0.9979 1924982 ChemDiv1_025715 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cccc(c5)C(F)(F)F)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A20 compound treatment 662512.0 178000.0 0.37 618740.0 149000.0 0.32 0.4891 0.9979 1342478 ChemDiv1_025716 COc1cc(cc(OC)c1OC(=O)C)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A21 compound treatment 657600.0 173000.0 0.36 602231.0 133000.0 0.29 0.4566 0.9941 1981859 ChemDiv1_025717 C(Cn1c(csc1=Nc2ccccc2)c3ccc(cc3)C4CCCCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A22 compound treatment 631457.0 147000.0 0.3 604910.0 136000.0 0.29 0.4226 0.9998 1981860 ChemDiv1_025718 CCCCOc1ccc(cc1)C2C=C(Nc3ccc(F)cc3)C(=O)N2c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A23 mock treatment 620535.0 136000.0 0.28 589779.0 120000.0 0.26 0.3835 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 A24 mock treatment 218763.0 -265000.0 -0.55 198218.0 -271000.0 -0.59 -0.8023 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B01 compound treatment 625851.0 142000.0 0.29 580887.0 112000.0 0.24 0.3776 0.9955 1191949 ChemDiv1_025719 COc1ccc(cc1OC)c2nc3c([nH]2)c4ccccc4c5ccc(I)cc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B02 compound treatment 659208.0 175000.0 0.36 628066.0 159000.0 0.34 0.4985 0.9997 1215420 ChemDiv1_025720 CC1(CC2c3ccccc3C1c4ccccc24)C(=O)NCc5cccnc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B03 compound treatment 695309.0 211000.0 0.44 648180.0 179000.0 0.39 0.582 0.9983 1981861 ChemDiv1_025721 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4cc(C)ccc4C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B04 compound treatment 694239.0 210000.0 0.43 643147.0 174000.0 0.38 0.5727 0.9975 1981862 ChemDiv1_025722 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C=C)c3cc(C)c(C)cc23)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B05 compound treatment 710838.0 227000.0 0.47 652642.0 183000.0 0.4 0.6115 0.9966 1981863 ChemDiv1_025723 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(N5CCC(Cc6ccccc6)CC5)c(c4)[N+](=O)[O-])ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B06 compound treatment 713713.0 230000.0 0.47 624466.0 155000.0 0.34 0.5726 0.9858 1981864 ChemDiv1_025724 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B07 compound treatment 739001.0 255000.0 0.53 704795.0 236000.0 0.51 0.7324 0.9999 1981865 ChemDiv1_025725 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cc(Br)ccc4NC3c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B08 compound treatment 726735.0 243000.0 0.5 708010.0 239000.0 0.52 0.7194 0.9999 1981866 ChemDiv1_025726 CC(=O)C1=NN(C(N1c2ccc(Cl)c(Cl)c2)c3ccccc3OCc4c(Cl)cccc4Cl)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B09 compound treatment 752819.0 269000.0 0.55 725418.0 256000.0 0.55 0.7841 1.0 1232332 ChemDiv1_025727 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B10 compound treatment 755452.0 271000.0 0.56 717346.0 248000.0 0.54 0.7756 0.9998 1981867 ChemDiv1_025728 CC(C)(C)c1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)c6ccc(cc6)[N+](=O)[O-])c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B11 compound treatment 736226.0 252000.0 0.52 706761.0 237000.0 0.51 0.7314 1.0 1402475 ChemDiv1_025729 COc1cc2C(OC3=C(C(=O)c4ccccc34)c2cc1OC)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B12 compound treatment 745531.0 261000.0 0.54 679960.0 211000.0 0.46 0.7039 0.9965 1981868 ChemDiv1_025730 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccc(cc3)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B13 compound treatment 753971.0 270000.0 0.56 708343.0 239000.0 0.52 0.7597 0.9993 1929796 ChemDiv1_025731 Clc1ccc(cc1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B14 compound treatment 721983.0 238000.0 0.49 701032.0 232000.0 0.5 0.7018 0.9999 1939877 ChemDiv1_025732 Fc1ccc(cc1)C2C3(OC(c4ccc(Cl)cc4)C25C(=O)c6ccccc6C5=O)C(=O)c7ccccc7C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B15 compound treatment 780592.0 296000.0 0.61 740907.0 272000.0 0.59 0.8484 0.9998 1454664 ChemDiv1_025733 CC1(C)CC(=O)c2cc(c3ccc(Br)cc3)n(CC(=O)OCC(=O)c4ccc(Br)cc4)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B16 compound treatment 728353.0 244000.0 0.5 694358.0 225000.0 0.49 0.7009 0.9999 1543517 ChemDiv1_025734 CC(C)COCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4Cl)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B17 compound treatment 766578.0 282000.0 0.58 750903.0 282000.0 0.61 0.8432 0.9998 1981869 ChemDiv1_025735 Clc1ccc(C=c2sc3nnc(c4ccccc4)n3c2=O)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B18 compound treatment 730017.0 246000.0 0.51 693192.0 224000.0 0.48 0.7015 0.9997 1133759 ChemDiv1_025736 CC(C)COCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccc(C)cc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B19 compound treatment 746096.0 262000.0 0.54 708619.0 239000.0 0.52 0.7486 0.9998 1981870 ChemDiv1_025737 Clc1ccc(cc1)c2nc([nH]c2c3ccccc3)c4ccc(C#Cc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B20 compound treatment 717341.0 233000.0 0.48 670516.0 201000.0 0.44 0.6483 0.9988 1981871 ChemDiv1_025738 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cccc(C(=O)N5CCCC5)c4NC3c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B21 compound treatment 742994.0 259000.0 0.53 695464.0 226000.0 0.49 0.724 0.999 1981872 ChemDiv1_025739 CCOC(=O)C1=NN(C2C1C(=O)N(C2=O)c3ccccc3Cl)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B22 compound treatment 679951.0 196000.0 0.4 658390.0 189000.0 0.41 0.5752 1.0 1981873 ChemDiv1_025740 CCOC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccccc5C)c6ccccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B23 mock treatment 710722.0 227000.0 0.47 649995.0 181000.0 0.39 0.6073 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 B24 mock treatment 216554.0 -268000.0 -0.55 221695.0 -248000.0 -0.54 -0.7696 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C01 compound treatment 622994.0 139000.0 0.29 596834.0 128000.0 0.28 0.3978 0.9998 1981874 ChemDiv1_025741 O(c1ccccc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5cccc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C02 compound treatment 649532.0 165000.0 0.34 636454.0 167000.0 0.36 0.4972 0.9996 1604216 ChemDiv1_025742 CC1(CC2c3ccccc3C1c4ccccc24)C(=O)NCc5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C03 compound treatment 697464.0 213000.0 0.44 701837.0 233000.0 0.5 0.6672 0.9978 1981875 ChemDiv1_025743 COc1ccc(C=c2sc3nnc(c4ccc(C)cc4)n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C04 compound treatment 690226.0 206000.0 0.43 688970.0 220000.0 0.48 0.637 0.9985 1667712 ChemDiv1_025744 CCN(CC)Cc1c(nnn1c2nonc2N)C(=O)OC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C05 compound treatment 695499.0 211000.0 0.44 692639.0 223000.0 0.48 0.6503 0.9987 1981876 ChemDiv1_025745 CC(=O)C1=NN(c2ccccc2[N+](=O)[O-])C3(S1)N(N=C(c4ccc(C)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C06 compound treatment 710423.0 226000.0 0.47 686949.0 218000.0 0.47 0.6634 1.0 1594285 ChemDiv1_025746 Cc1ccc(OCc2nn(C3CC(=O)C4OCC3O4)c(=S)n2C)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C07 compound treatment 719137.0 235000.0 0.49 718559.0 249000.0 0.54 0.7245 0.9986 1981877 ChemDiv1_025747 CC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C08 compound treatment 727584.0 243000.0 0.5 717597.0 248000.0 0.54 0.7353 0.9994 1656285 ChemDiv1_025748 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3ccc(Cl)cc3)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C09 compound treatment 729421.0 245000.0 0.51 741288.0 272000.0 0.59 0.7743 0.9972 1172841 ChemDiv1_025749 Cc1ccc(NC(=O)C2C3CCCC2C3c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C10 compound treatment 720690.0 237000.0 0.49 710371.0 241000.0 0.52 0.7142 0.9994 1619528 ChemDiv1_025750 CC1CCN(Cc2c(nnn2c3nonc3N)C(=O)O)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C11 compound treatment 742789.0 259000.0 0.53 715745.0 246000.0 0.53 0.7547 1.0 1981878 ChemDiv1_025751 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(cc5)C(=O)O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C12 compound treatment 719829.0 236000.0 0.49 719025.0 250000.0 0.54 0.7262 0.9986 1145485 ChemDiv1_025752 CC1(C)Cc2ccccc2C(=C3C(=O)CCCC3=O)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C13 compound treatment 746269.0 262000.0 0.54 729790.0 261000.0 0.56 0.7813 0.9998 1981879 ChemDiv1_025753 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccccc3F)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C14 compound treatment 728584.0 244000.0 0.5 753336.0 284000.0 0.61 0.7915 0.9952 1174602 ChemDiv1_025754 COc1ccc(cc1OC)C2(CNC(=O)C(c3ccccc3)c4ccccc4)CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C15 compound treatment 767779.0 284000.0 0.59 796012.0 327000.0 0.71 0.914 0.9956 1981880 ChemDiv1_025755 CC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C16 compound treatment 713174.0 229000.0 0.47 736761.0 267000.0 0.58 0.7436 0.9949 1210773 ChemDiv1_025756 Cc1ccc(NC(=O)C2C3CCCC2C3c4ccccc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C17 compound treatment 742812.0 259000.0 0.53 762424.0 293000.0 0.63 0.8262 0.9963 1981881 ChemDiv1_025757 O=C(Cc1cccc2ccccc12)N/N=C/c3ccc(Sc4nnc(c5ccccc5)n4c6ccccc6)o3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C18 compound treatment 690893.0 207000.0 0.43 755991.0 287000.0 0.62 0.7405 0.9833 1174751 ChemDiv1_025758 CCCc1n2CC(=C(C)c2cc3nc(C(=O)OCC)c(C)c13)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C19 compound treatment 692167.0 208000.0 0.43 734216.0 265000.0 0.57 0.7091 0.9898 1169133 ChemDiv1_025759 CCOc1cc(cc(Br)c1O)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C20 compound treatment 707128.0 223000.0 0.46 693416.0 224000.0 0.49 0.6685 0.9997 1981882 ChemDiv1_025760 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4ccc(cc4)C5CCCCC5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C21 compound treatment 699522.0 215000.0 0.44 730631.0 261000.0 0.57 0.7143 0.9929 1981883 ChemDiv1_025761 CC1(C)SC(=S)N(/N=C/c2cccnc2)C1N(O)C(=O)Nc3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C22 compound treatment 695615.0 211000.0 0.44 683534.0 214000.0 0.46 0.6365 0.9995 1981884 ChemDiv1_025762 CC(C)CCC1(C)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C23 mock treatment 686955.0 203000.0 0.42 681507.0 212000.0 0.46 0.6208 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 C24 mock treatment 244503.0 -240000.0 -0.49 217172.0 -252000.0 -0.55 -0.7357 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D01 compound treatment 622464.0 138000.0 0.29 587725.0 118000.0 0.26 0.3831 0.9986 1981885 ChemDiv1_025763 CCOC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4ccc(cc4)C(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D02 compound treatment 613357.0 129000.0 0.27 596756.0 127000.0 0.28 0.3837 0.9999 1981886 ChemDiv1_025764 CCCCCCCC(=O)N1C2CCN(C)CC2c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D03 compound treatment 708785.0 225000.0 0.46 679654.0 210000.0 0.46 0.6498 1.0 1981887 ChemDiv1_025765 COC(=O)c1cccc(c1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3(C)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D04 compound treatment 693585.0 209000.0 0.43 678035.0 209000.0 0.45 0.6252 0.9998 1981888 ChemDiv1_025766 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)c(C)cc4N(C(=O)C=C)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D05 compound treatment 731505.0 247000.0 0.51 687096.0 218000.0 0.47 0.6944 0.9992 1981889 ChemDiv1_025767 CN(C)c1ccc2c3c(ccc(N(C)C)c13)C4(OC2(c5ccc(N(C)C)c6c(ccc4c56)N(C)C)C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D06 compound treatment 627018.0 143000.0 0.29 597133.0 128000.0 0.28 0.4042 0.9995 1981890 ChemDiv1_025768 CCCCCCCCCC(=O)N1C2CCN(C)CC2c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D07 compound treatment 745243.0 261000.0 0.54 716452.0 247000.0 0.53 0.7594 1.0 1981891 ChemDiv1_025769 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cc(Cl)cc(Cl)c4NC3c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D08 compound treatment 888481.0 404000.0 0.83 877399.0 408000.0 0.88 1.2148 0.9996 1981892 ChemDiv1_025770 CC(=O)C1=NN(C(N1c2ccc(Cl)cc2)c3ccccc3OCc4ccc(Cl)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D09 compound treatment 702470.0 218000.0 0.45 659911.0 191000.0 0.41 0.6104 0.999 1037816 ChemDiv1_025771 O=C1OC(OC2CCCCC2)(c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D10 compound treatment 712758.0 229000.0 0.47 688268.0 219000.0 0.47 0.6688 1.0 1981893 ChemDiv1_025772 CCOc1ccc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C(C)(C)N(C(=O)Cc4ccc(F)cc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D11 compound treatment 765108.0 281000.0 0.58 734176.0 265000.0 0.57 0.8155 1.0 1981894 ChemDiv1_025773 CN1CCC2C(C1)c3cc(C)ccc3N2C(=S)NC4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D12 compound treatment 731539.0 247000.0 0.51 693714.0 224000.0 0.49 0.7046 0.9997 1545107 ChemDiv1_025774 COc1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D13 compound treatment 750325.0 266000.0 0.55 715140.0 246000.0 0.53 0.7648 0.9999 1718266 ChemDiv1_025775 Clc1ccc(C(=O)Nc2oc(c(c2C#N)c3ccccc3)c4ccccc4)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D14 compound treatment 739336.0 255000.0 0.53 720184.0 251000.0 0.54 0.7564 0.9999 1981895 ChemDiv1_025776 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cccc(OC)c4N(C(=O)c5ccc(F)cc5)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D15 compound treatment 798448.0 314000.0 0.65 769807.0 301000.0 0.65 0.9187 1.0 1704533 ChemDiv1_025777 CC1(C)CC(=O)c2cc(c3ccccc3)n(CC(=O)OCC(=O)c4ccccc4)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D16 compound treatment 744134.0 260000.0 0.54 708447.0 239000.0 0.52 0.7455 0.9998 1202155 ChemDiv1_025778 O=C(Cc1c(Sc2ccccc2)c3ccccc3n1Cc4ccccc4)Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D17 compound treatment 786488.0 302000.0 0.62 745664.0 276000.0 0.6 0.8643 0.9998 1981896 ChemDiv1_025779 O(c1ccccc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5ccc(C#Cc6ccccc6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D18 compound treatment 710738.0 227000.0 0.47 731461.0 262000.0 0.57 0.732 0.9954 1696132 ChemDiv1_025780 COc1ccc(NC(=O)c2c(NC(=O)c3cccc(C)c3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D19 compound treatment 748545.0 264000.0 0.55 739646.0 270000.0 0.59 0.7997 0.9994 1981897 ChemDiv1_025781 COc1ccc(/C=C/C23NC(=O)CN3c4ccccc4C2(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D20 compound treatment 729808.0 246000.0 0.51 686549.0 217000.0 0.47 0.6911 0.9993 1924772 ChemDiv1_025782 CC(=O)c1cccc(c1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D21 compound treatment 754295.0 270000.0 0.56 730453.0 261000.0 0.57 0.794 1.0 1981898 ChemDiv1_025783 COc1ccc2ccccc2c1C3N(CCN3c4ccc(C)cc4)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D22 compound treatment 712906.0 229000.0 0.47 689832.0 221000.0 0.48 0.6714 1.0 1981899 ChemDiv1_025784 Cc1ccccc1C2(SC3(SC(=NN3c4ccccc4)C(=O)c5ccccc5)c6ccccc62)c7ccccc7C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D23 mock treatment 715878.0 232000.0 0.48 682948.0 214000.0 0.46 0.6652 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 D24 mock treatment 219213.0 -265000.0 -0.55 192689.0 -277000.0 -0.6 -0.8101 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E01 compound treatment 602441.0 118000.0 0.24 580639.0 111000.0 0.24 0.3431 1.0 1190152 ChemDiv1_025785 Oc1ccc(cc1O)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E02 compound treatment 619467.0 135000.0 0.28 607553.0 138000.0 0.3 0.4091 0.9994 1981900 ChemDiv1_025786 FC(F)(F)c1cccc(N=c2scc(c3ccc(Br)cc3)n2CCc4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E03 compound treatment 693620.0 209000.0 0.43 671524.0 202000.0 0.44 0.6152 1.0 1981901 ChemDiv1_025787 CCOC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E04 compound treatment 667359.0 183000.0 0.38 688858.0 220000.0 0.48 0.6034 0.9936 1981902 ChemDiv1_025788 Ic1ccc2c(c1)c3nc([nH]c3c4cc(I)ccc42)c5cccc(Oc6ccccc6)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E05 compound treatment 698247.0 214000.0 0.44 699918.0 231000.0 0.5 0.6655 0.9982 1981903 ChemDiv1_025789 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E06 compound treatment 718655.0 234000.0 0.48 673296.0 204000.0 0.44 0.6545 0.9989 1301890 ChemDiv1_025790 O=C1CC(C2COC1O2)n3nc(Cc4ccccc4)n(c5ccccc5)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E07 compound treatment 719647.0 235000.0 0.49 706880.0 238000.0 0.51 0.7073 0.9996 1930067 ChemDiv1_025791 CCOC(=O)C1(C)C=C(Nc2ccc(OC)cc2)C(=O)N1c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E08 compound treatment 729444.0 245000.0 0.51 728953.0 260000.0 0.56 0.7554 0.9986 1981904 ChemDiv1_025792 COc1ccc(cc1)N2C(=O)CC(C3=C2CC(C)(C)CC3=O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E09 compound treatment 744301.0 260000.0 0.54 733418.0 264000.0 0.57 0.7839 0.9995 1981905 ChemDiv1_025793 COc1ccc(cc1Br)c2csc(=Nc3ccc(F)cc3)n2CCc4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E10 compound treatment 702143.0 218000.0 0.45 697934.0 229000.0 0.49 0.6681 0.9989 1596274 ChemDiv1_025794 CCN1C(=c2sc(=C3SC(=S)N(C4CCCCC4)C3=O)n(CC)c2=O)C=Cc5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E11 compound treatment 707072.0 223000.0 0.46 689615.0 220000.0 0.48 0.6626 0.9998 1981906 ChemDiv1_025795 CNc1oc(nc1P(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E12 compound treatment 702082.0 218000.0 0.45 709530.0 240000.0 0.52 0.6858 0.9974 1575922 ChemDiv1_025796 CCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccccc4O)C(=O)CC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E13 compound treatment 706807.0 223000.0 0.46 703038.0 234000.0 0.51 0.6827 0.9988 1981907 ChemDiv1_025797 S=c1sc2SCC(=C(C#N)C#N)CSc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E14 compound treatment 696393.0 212000.0 0.44 719255.0 250000.0 0.54 0.6923 0.9945 1254910 ChemDiv1_025798 COc1ccc(cc1OC)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E15 compound treatment 738333.0 254000.0 0.52 777998.0 309000.0 0.67 0.8435 0.9928 1138631 ChemDiv1_025799 Ic1ccc(NC(=O)C2C3CCCC2C3c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E16 compound treatment 770052.0 286000.0 0.59 732839.0 264000.0 0.57 0.8207 0.9999 1588730 ChemDiv1_025800 CCCS(=O)(=O)c1c(C(=O)c2ccc(CC)cc2)n3cc(C)cc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E17 compound treatment 738255.0 254000.0 0.52 756999.0 288000.0 0.62 0.8112 0.9964 1981908 ChemDiv1_025801 O=C(N/N=C/c1ccc(Sc2nnc(c3ccccc3)n2c4ccccc4)o1)c5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E18 compound treatment 690059.0 206000.0 0.43 701949.0 233000.0 0.5 0.6566 0.9964 1981909 ChemDiv1_025802 CCCCCc1n2CC(=C(C)c2cc3nc(C(=O)OCC)c(C)c13)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E19 compound treatment 716478.0 232000.0 0.48 711634.0 242000.0 0.52 0.71 0.999 1981910 ChemDiv1_025803 Fc1ccc(N=c2scc(c3ccc(cc3)C4CCCCC4)n2CCc5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E20 compound treatment 694234.0 210000.0 0.43 678422.0 209000.0 0.45 0.6267 0.9998 1282526 ChemDiv1_025804 O=C1CCCC(=O)C1=C2NC3(Cc4ccccc24)CCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E21 compound treatment 711749.0 228000.0 0.47 707538.0 238000.0 0.52 0.6968 0.9989 1981911 ChemDiv1_025805 CCCC1(CCC)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E22 compound treatment 710178.0 226000.0 0.47 721416.0 252000.0 0.55 0.7158 0.997 1222258 ChemDiv1_025806 COc1ccc(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E23 mock treatment 697243.0 213000.0 0.44 694734.0 225000.0 0.49 0.6561 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 E24 mock treatment 236031.0 -248000.0 -0.51 239235.0 -230000.0 -0.5 -0.7143 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F01 compound treatment 640973.0 157000.0 0.32 603983.0 135000.0 0.29 0.435 0.9986 1981912 ChemDiv1_025807 COC(=O)c1ccc(cc1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F02 compound treatment 688557.0 204000.0 0.42 653907.0 185000.0 0.4 0.5809 0.9996 1981913 ChemDiv1_025808 Brc1ccc(cc1)C2=CC(NC(=S)N2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F03 compound treatment 716495.0 232000.0 0.48 690884.0 222000.0 0.48 0.6783 1.0 1981914 ChemDiv1_025809 Cc1ccc(cc1)c2[nH]c(nc2c3ccccc3)c4ccc(cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F04 compound treatment 695715.0 212000.0 0.44 688641.0 219000.0 0.47 0.6445 0.9991 1981915 ChemDiv1_025810 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)c(C)cc4N(C(=O)C(F)(F)F)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F05 compound treatment 733317.0 249000.0 0.51 673601.0 204000.0 0.44 0.6764 0.9972 1945297 ChemDiv1_025811 COc1ccc2ccccc2c1c3nnc4ccc5ccccc5n34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F06 compound treatment 717912.0 234000.0 0.48 696222.0 227000.0 0.49 0.6885 1.0 1182467 ChemDiv1_025812 COc1ccc(cc1)c2nn(CN3CCC4(CC3)OCCO4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F07 compound treatment 738135.0 254000.0 0.52 717416.0 248000.0 0.54 0.7505 0.9999 1981916 ChemDiv1_025813 CCOC(=O)c1ccc2NC(C3CC(Sc4ccccc4[N+](=O)[O-])C(Cl)C3c2c1)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F08 compound treatment 769236.0 285000.0 0.59 765240.0 296000.0 0.64 0.869 0.9991 1981917 ChemDiv1_025814 CC(=O)C1=NN(C(N1c2ccc(Cl)c(Cl)c2)c3ccccc3OCc4c(Cl)cccc4Cl)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F09 compound treatment 766438.0 282000.0 0.58 743544.0 274000.0 0.59 0.8318 1.0 1981918 ChemDiv1_025815 COc1ccc(/C=C/2\CC(C/C(=C\c3ccc(OC)c(OC)c3)/C2=O)C(C)(C)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F10 compound treatment 774881.0 291000.0 0.6 780269.0 311000.0 0.67 0.9003 0.9984 1981919 ChemDiv1_025816 Clc1ccc(cc1)c2nn(cc2/C=C(\NC(=O)c3ccc(Cl)cc3Cl)/C(=O)NCc4ccccn4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F11 compound treatment 763793.0 280000.0 0.58 760064.0 291000.0 0.63 0.8532 0.9991 1338055 ChemDiv1_025817 CC1(C)c2ccccc2N(CC=C)C31Oc4ccc5ccccc5c4C=C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F12 compound treatment 736160.0 252000.0 0.52 714136.0 245000.0 0.53 0.7426 1.0 1981920 ChemDiv1_025818 CC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)SC(c4ccccc43)(c5ccccc5C)c6ccccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F13 compound treatment 796109.0 312000.0 0.64 793753.0 324000.0 0.7 0.9519 0.9991 1229370 ChemDiv1_025819 COc1ccc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccc(OC)c(OC)c4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F14 compound treatment 863240.0 379000.0 0.78 859304.0 390000.0 0.84 1.1502 0.9993 1705353 ChemDiv1_025820 NS(=O)(=O)c1ccc(cc1)n2c(c3C(=O)c4ccccc4C(=O)c3c2c5ccc(Cl)cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F15 compound treatment 868742.0 385000.0 0.79 781976.0 313000.0 0.68 1.0399 0.9968 1158416 ChemDiv1_025821 CCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F16 compound treatment 712590.0 228000.0 0.47 746264.0 277000.0 0.6 0.7573 0.9929 1712230 ChemDiv1_025822 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cccc(OCc5ccccc5F)c4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F17 compound treatment 748590.0 264000.0 0.55 747379.0 278000.0 0.6 0.8116 0.9988 1981921 ChemDiv1_025823 [O-][N+](=O)c1ccc(cc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5c6ccccc6c(Cl)c7ccccc57 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F18 compound treatment 669108.0 185000.0 0.38 661563.0 192000.0 0.42 0.5642 0.9991 1176218 ChemDiv1_025824 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N2CCCCC2)c3ccccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F19 compound treatment 769119.0 285000.0 0.59 755269.0 286000.0 0.62 0.8536 0.9997 1729213 ChemDiv1_025825 COc1cccc(c1)C2N(CC=C)C(=O)C(=C2C(=O)c3ccc(Br)cc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F20 compound treatment 741675.0 258000.0 0.53 730703.0 261000.0 0.57 0.776 0.9995 1981922 ChemDiv1_025826 Sc1nnc2c3ccccc3n(CCc4ccccc4)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F21 compound treatment 733217.0 249000.0 0.51 701791.0 233000.0 0.5 0.7194 0.9999 1487392 ChemDiv1_025827 CC1C(O)CCN(C)C1c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F22 compound treatment 3148560.0 2660000.0 5.5 3663457.0 3190000.0 6.91 8.7777 0.9936 1179903 ChemDiv1_025828 Nc1c2-c3ccccc3C(=O)c4cccc(n(C5CCCCC5)c1=O)c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F23 mock treatment 707949.0 224000.0 0.46 669377.0 200000.0 0.43 0.6329 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 F24 mock treatment 213266.0 -271000.0 -0.56 252796.0 -216000.0 -0.47 -0.7268 -0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G01 compound treatment 621822.0 138000.0 0.28 577228.0 108000.0 0.23 0.3661 0.9953 1130140 ChemDiv1_025829 CCOc1cc(cc(Br)c1O)C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G02 compound treatment 659794.0 176000.0 0.36 635406.0 166000.0 0.36 0.5106 1.0 1981923 ChemDiv1_025830 FC(F)(F)c1cccc(N=c2scc(c3ccc(cc3)C4CCCCC4)n2CCc5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G03 compound treatment 703013.0 219000.0 0.45 675770.0 206000.0 0.45 0.6355 1.0 1981924 ChemDiv1_025831 CC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G04 compound treatment 693640.0 209000.0 0.43 660435.0 191000.0 0.41 0.5983 0.9998 1981925 ChemDiv1_025832 COc1cc2C(OC(=O)c2cc1OC)C(Cl)(Cl)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G05 compound treatment 711450.0 227000.0 0.47 688440.0 219000.0 0.47 0.6672 1.0 1981926 ChemDiv1_025833 CCc1ccc(NC2=CC(N(C2=O)c3ccc(CC)cc3)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G06 compound treatment 710152.0 226000.0 0.47 676215.0 207000.0 0.45 0.6466 0.9998 1981927 ChemDiv1_025834 O=C(CSc1nc(cc(n1)c2ccccc2)c3ccccc3)NCc4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G07 compound treatment 729824.0 246000.0 0.51 740537.0 271000.0 0.59 0.7737 0.9973 1981928 ChemDiv1_025835 COc1ccc2S/C(=C/3\SC(=S)N(C)C3=O)/N(C4CCCCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G08 compound treatment 738327.0 254000.0 0.52 732532.0 263000.0 0.57 0.7739 0.9992 1675313 ChemDiv1_025836 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(Nc5cccc(Cl)c5)ccc1c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G09 compound treatment 723000.0 239000.0 0.49 706363.0 237000.0 0.51 0.7114 0.9998 1981929 ChemDiv1_025837 Fc1ccc(NC2=CC(N(C2=O)c3ccc(F)cc3)c4cccc5ccccc45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G10 compound treatment 775454.0 291000.0 0.6 770630.0 301000.0 0.65 0.8864 0.9992 1981930 ChemDiv1_025838 CCn1c(=O)c(=C/C=C\2/N(C)c3ccc(cc3C2(C)C)c4ccccc4)sc1=C5C(=NN(C5=O)c6ccccc6)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G11 compound treatment 708947.0 225000.0 0.46 688248.0 219000.0 0.47 0.6632 0.9999 1950132 ChemDiv1_025839 Clc1ccc(cc1)c2nc(c(o2)N3CCOCC3)P(=O)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G12 compound treatment 711156.0 227000.0 0.47 702501.0 233000.0 0.5 0.6883 0.9993 1981931 ChemDiv1_025840 CC(C)(C)C1=CC2(Nc3ccccc3OC2c4ccccc4)C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G13 compound treatment 721590.0 237000.0 0.49 744278.0 275000.0 0.6 0.7674 0.9953 1543965 ChemDiv1_025841 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccc(C)cc3)O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G14 compound treatment 718741.0 235000.0 0.48 732066.0 263000.0 0.57 0.7446 0.9968 1981932 ChemDiv1_025842 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccccc5)c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G15 compound treatment 731955.0 248000.0 0.51 743905.0 275000.0 0.59 0.782 0.9972 1981933 ChemDiv1_025843 CC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G16 compound treatment 712353.0 228000.0 0.47 720206.0 251000.0 0.54 0.7171 0.9975 1589077 ChemDiv1_025844 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3cccc(C(=O)N)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G17 compound treatment 741402.0 257000.0 0.53 751663.0 282000.0 0.61 0.8076 0.9975 1380995 ChemDiv1_025845 Fc1cccc(c1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G18 compound treatment 709082.0 225000.0 0.46 709176.0 240000.0 0.52 0.6954 0.9984 1981934 ChemDiv1_025846 NS(=O)(=O)c1ccc(CCn2c(csc2=Nc3ccccc3)c4ccc(cc4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G19 compound treatment 741316.0 257000.0 0.53 704902.0 236000.0 0.51 0.7359 0.9998 1981935 ChemDiv1_025847 CSC1=N/C(=N\c2ccccc2)/C3(CCCCC3)N1c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G20 compound treatment 726910.0 243000.0 0.5 699056.0 230000.0 0.5 0.706 1.0 1614944 ChemDiv1_025848 Cc1c(oc2c(C)c3oc(=O)cc(C)c3cc12)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G21 compound treatment 703607.0 219000.0 0.45 682799.0 214000.0 0.46 0.6471 0.9999 1981936 ChemDiv1_025849 CCCCCCC1(C)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G22 compound treatment 705026.0 221000.0 0.46 724944.0 256000.0 0.55 0.7137 0.9954 1981937 ChemDiv1_025850 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(Cc5ccc(Cl)c(Cl)c5)nc4c6ccccc6)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G23 mock treatment 704702.0 221000.0 0.46 696413.0 227000.0 0.49 0.6695 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 G24 mock treatment 208627.0 -276000.0 -0.57 188144.0 -281000.0 -0.61 -0.8325 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H01 compound treatment 639562.0 155000.0 0.32 612555.0 143000.0 0.31 0.4461 0.9999 1981938 ChemDiv1_025851 Clc1c2ccccc2c(c3nc(c([nH]3)c4ccc(Oc5ccccc5)cc4)c6ccc(Oc7ccccc7)cc6)c8ccccc18 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H02 compound treatment 681078.0 197000.0 0.41 638678.0 169000.0 0.37 0.5467 0.9987 1981939 ChemDiv1_025852 CC(C)(C)C1=CC2(Nc3cc(Cl)ccc3OC2c4ccc(cc4)[N+](=O)[O-])C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H03 compound treatment 698783.0 215000.0 0.44 680013.0 211000.0 0.46 0.6358 0.9999 1234232 ChemDiv1_025853 CCc1ccc(cc1)C2(CC2C(=O)Nc3ccc(F)cc3)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H04 compound treatment 683810.0 200000.0 0.41 676477.0 207000.0 0.45 0.6085 0.9991 1981940 ChemDiv1_025854 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccccc4N(C(=O)C(C)C)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H05 compound treatment 687723.0 204000.0 0.42 653632.0 184000.0 0.4 0.5793 0.9997 1945370 ChemDiv1_025855 C1Oc2ccc(cc2O1)c3nnc4ccc5ccccc5n34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H06 compound treatment 845076.0 361000.0 0.75 789324.0 320000.0 0.69 1.0166 0.9993 1981941 ChemDiv1_025856 CC(=O)C1=NN(C(N1c2ccc(C)cc2)c3cccc(OCc4c(Cl)cccc4Cl)c3)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H07 compound treatment 726320.0 242000.0 0.5 690834.0 222000.0 0.48 0.6925 0.9998 1981942 ChemDiv1_025857 CCOc1ccccc1/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H08 compound treatment 737910.0 254000.0 0.52 679152.0 210000.0 0.45 0.6916 0.9975 1981943 ChemDiv1_025858 CCOC(=O)C1(C)C=C(Nc2cccc(c2)[N+](=O)[O-])C(=O)N1c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H09 compound treatment 744548.0 260000.0 0.54 721142.0 252000.0 0.55 0.7655 1.0 1981944 ChemDiv1_025859 CC(C)(C)C1C/C(=C\c2cccc(Br)c2)/C(=O)\C(=C\c3cccc(Br)c3)\C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H10 compound treatment 737437.0 253000.0 0.52 646369.0 177000.0 0.38 0.6407 0.9884 1523616 ChemDiv1_025860 COc1ccc(cc1)C2(CC(NC(=S)N2)c3ccccc3)c4ccc(OC(=O)C)cc4OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H11 compound treatment 733865.0 250000.0 0.52 725452.0 256000.0 0.55 0.7565 0.9993 1981945 ChemDiv1_025861 CCOC(=O)C(NC(=O)c1ccccc1)(Nc2nc3ccccc3nc2C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H12 compound treatment 703115.0 219000.0 0.45 693939.0 225000.0 0.49 0.6634 0.9993 1660165 ChemDiv1_025862 CNC1(Oc2ccccc2C(=C1C)C#Cc3ccccc3)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H13 compound treatment 729730.0 246000.0 0.51 770914.0 302000.0 0.65 0.8201 0.9922 1981946 ChemDiv1_025863 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc(F)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H14 compound treatment 705479.0 221000.0 0.46 679932.0 211000.0 0.46 0.6454 1.0 1981947 ChemDiv1_025864 CC(C)CCOCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H15 compound treatment 766815.0 283000.0 0.58 781735.0 312000.0 0.68 0.8908 0.9973 1981948 ChemDiv1_025865 NC1=C(C#N)C(C(=c2sc(=Cc3ccc(OCc4ccccc4)cc3)c(=O)n12)C#N)c5ccc(OCc6ccccc6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H16 compound treatment 751523.0 267000.0 0.55 706957.0 238000.0 0.51 0.754 0.9994 1981949 ChemDiv1_025866 OC(=O)CN1C(=O)/C(=C/2\Sc3ccccc3N2CCCS(=O)(=O)O)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H17 compound treatment 712970.0 229000.0 0.47 729681.0 260000.0 0.56 0.7325 0.9961 1780526 ChemDiv1_025867 [O-][N+](=O)c1cc(ccc1Br)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H18 compound treatment 637396.0 153000.0 0.32 603160.0 134000.0 0.29 0.4285 0.999 1981950 ChemDiv1_025868 OC(=O)c1cccc2C3C(Cl)C(CC3C(Nc12)c4cccc(Br)c4)Sc5ccccc5[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H19 compound treatment 728595.0 244000.0 0.5 701679.0 232000.0 0.5 0.7124 1.0 1981951 ChemDiv1_025869 CCOC(=O)C1N(C(=O)C(=C1C)Nc2ccc(OC)cc2)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H20 compound treatment 724221.0 240000.0 0.5 704578.0 235000.0 0.51 0.7105 0.9999 1981952 ChemDiv1_025870 CCN1C(=O)/C(=C/2\Sc3ccc(OC)cc3N2C4CCCCC4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H21 compound treatment 725555.0 241000.0 0.5 729493.0 260000.0 0.56 0.7506 0.9981 1434947 ChemDiv1_025871 Ic1ccc(cc1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H22 compound treatment 701505.0 217000.0 0.45 698171.0 229000.0 0.5 0.6675 0.9988 1981953 ChemDiv1_025872 O=P(CCCCOc1ccccc1CP(=O)(c2ccccc2)c3ccccc3)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H23 mock treatment 714648.0 230000.0 0.48 688710.0 219000.0 0.47 0.6722 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 H24 mock treatment 219255.0 -265000.0 -0.55 194123.0 -275000.0 -0.6 -0.8078 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I01 compound treatment 615520.0 131000.0 0.27 589376.0 120000.0 0.26 0.3755 0.9998 1981954 ChemDiv1_025873 C1Oc2ccc(cc2O1)C3N(N=C(N3c4ccc(cc4)N5CCOCC5)c6ccccc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I02 compound treatment 650039.0 166000.0 0.34 684654.0 215000.0 0.47 0.5717 0.9885 1981955 ChemDiv1_025874 Fc1ccc(cc1)c2csc(=Nc3cccc(c3)C(F)(F)F)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I03 compound treatment 695514.0 211000.0 0.44 679252.0 210000.0 0.45 0.6298 0.9998 1981956 ChemDiv1_025875 CCCCOC(=O)c1ccc(cc1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I04 compound treatment 681454.0 197000.0 0.41 667433.0 198000.0 0.43 0.5912 0.9997 1981957 ChemDiv1_025876 CC(=O)C1=NN(c2ccccc2C)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I05 compound treatment 713111.0 229000.0 0.47 681396.0 212000.0 0.46 0.6588 0.9999 1981958 ChemDiv1_025877 COc1cc(/C=N/c2c(C)n(C)n(c3ccccc3)c2=O)cc(OC)c1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I06 compound treatment 699223.0 215000.0 0.44 659542.0 190000.0 0.41 0.6051 0.9993 1981959 ChemDiv1_025878 FC(F)(F)c1cccc(N=c2scc(c3ccc4ccccc4c3)n2CCc5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I07 compound treatment 742194.0 258000.0 0.53 728287.0 259000.0 0.56 0.773 0.9997 1981960 ChemDiv1_025879 CCN1C(=O)/C(=C\2/Sc3ccccc3N2c4ccccc4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I08 compound treatment 724243.0 240000.0 0.5 685690.0 216000.0 0.47 0.6816 0.9996 1981961 ChemDiv1_025880 COc1cccc(C=c2sc3nnc(c4ccccc4)n3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I09 compound treatment 719362.0 235000.0 0.49 705913.0 237000.0 0.51 0.7055 0.9996 1981962 ChemDiv1_025881 CN(C)c1ccc(cc1)C2C=C(Nc3ccc(F)cc3)C(=O)N2c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I10 compound treatment 783932.0 300000.0 0.62 749219.0 280000.0 0.61 0.866 0.9999 1780542 ChemDiv1_025882 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4c5ccccc5cc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I11 compound treatment 742161.0 258000.0 0.53 723238.0 254000.0 0.55 0.7652 0.9999 1981963 ChemDiv1_025883 O=c1sc2SC3CCCCCCCCCCC3Sc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I12 compound treatment 701271.0 217000.0 0.45 658875.0 190000.0 0.41 0.6071 0.999 1981964 ChemDiv1_025884 CC(C)(C)C1=CC2(Nc3cc(Cl)ccc3OC2C=C)C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I13 compound treatment 741356.0 257000.0 0.53 723770.0 254000.0 0.55 0.7649 0.9998 1981965 ChemDiv1_025885 O=C(COc1cccc2ccccc12)N/N=C/c3ccc(Sc4nnc(c5ccccc5)n4c6ccccc6)o3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I14 compound treatment 727063.0 243000.0 0.5 695189.0 226000.0 0.49 0.7003 0.9999 1981966 ChemDiv1_025886 Brc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I15 compound treatment 725010.0 241000.0 0.5 713871.0 245000.0 0.53 0.7259 0.9995 1981967 ChemDiv1_025887 CC(=O)C1=NN(c2ccccc2[N+](=O)[O-])C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I16 compound treatment 720221.0 236000.0 0.49 727557.0 258000.0 0.56 0.7398 0.9977 1333637 ChemDiv1_025888 CCCS(=O)(=O)c1c(C(=O)c2ccc(OC)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I17 compound treatment 722113.0 238000.0 0.49 724553.0 255000.0 0.55 0.738 0.9983 1487625 ChemDiv1_025889 Fc1ccc(cc1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I18 compound treatment 685456.0 201000.0 0.42 694559.0 225000.0 0.49 0.6386 0.9968 1275789 ChemDiv1_025890 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Cl)cc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I19 compound treatment 721616.0 237000.0 0.49 704306.0 235000.0 0.51 0.7063 0.9998 1981968 ChemDiv1_025891 Cc1ccc(cc1C)c2csc(=Nc3ccccc3)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I20 compound treatment 694214.0 210000.0 0.43 711760.0 242000.0 0.52 0.6777 0.9955 1981969 ChemDiv1_025892 CCCCCC(=O)N1C2CCN(C)CC2c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I21 compound treatment 725860.0 242000.0 0.5 751616.0 282000.0 0.61 0.7849 0.9949 1144083 ChemDiv1_025893 CC(C)OC(=O)c1ccc2C(=O)c3ccccc3-c4onc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I22 compound treatment 708364.0 224000.0 0.46 684679.0 215000.0 0.47 0.6569 1.0 1981970 ChemDiv1_025894 CC(C)(C)C1=CC2(Nc3cc(Br)ccc3OC2c4ccccc4)C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I23 mock treatment 705706.0 222000.0 0.46 684013.0 215000.0 0.46 0.652 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 I24 mock treatment 219255.0 -265000.0 -0.55 206187.0 -263000.0 -0.57 -0.7894 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J01 compound treatment 632255.0 148000.0 0.31 611414.0 142000.0 0.31 0.4337 1.0 1981971 ChemDiv1_025895 CCOC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4ccc(cc4)C(C)(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J02 compound treatment 672882.0 189000.0 0.39 645289.0 176000.0 0.38 0.5448 0.9999 1981972 ChemDiv1_025896 CC(C)(C)C1=CC2(Nc3cc(Br)ccc3OC2c4ccc(cc4)[N+](=O)[O-])C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J03 compound treatment 686441.0 202000.0 0.42 674666.0 205000.0 0.44 0.6096 0.9995 1981973 ChemDiv1_025897 Fc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J04 compound treatment 681232.0 197000.0 0.41 670927.0 202000.0 0.44 0.5962 0.9994 1981974 ChemDiv1_025898 CCCCC(=O)N1c2ccc(OC)cc2C3=C(SC(=C(C(=O)OCC)C43SC(=C(S4)C(=O)OCC)C(=O)OCC)C(=O)OCC)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J05 compound treatment 715024.0 231000.0 0.48 687434.0 218000.0 0.47 0.6708 1.0 1945519 ChemDiv1_025899 Ic1cccc(c1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J06 compound treatment 772375.0 288000.0 0.59 760933.0 292000.0 0.63 0.867 0.9996 1981975 ChemDiv1_025900 COc1ccc(cc1)N2C(N(N=C2C(=O)C)c3ccc(Cl)cc3)c4ccc(OCc5c(Cl)cccc5Cl)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J07 compound treatment 751540.0 267000.0 0.55 716686.0 247000.0 0.54 0.7689 0.9999 1981976 ChemDiv1_025901 CCOc1cc(/C=N/NC(=O)c2nnn(c2CN3CCCCCC3)c4nonc4N)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J08 compound treatment 727513.0 243000.0 0.5 704486.0 235000.0 0.51 0.7152 1.0 1981977 ChemDiv1_025902 FC(F)(F)c1cccc(c1)N2C(c3c(n[nH]c3C2=O)c4ccccc4)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J09 compound treatment 747234.0 263000.0 0.54 737267.0 268000.0 0.58 0.7941 0.9995 1981978 ChemDiv1_025903 CC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J10 compound treatment 713723.0 230000.0 0.47 725757.0 256000.0 0.56 0.7276 0.9969 1507996 ChemDiv1_025904 CN(C)c1ccc(cc1)C(O)P(=O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J11 compound treatment 741880.0 258000.0 0.53 756673.0 287000.0 0.62 0.816 0.997 1981979 ChemDiv1_025905 CCOC(=O)C(NC(=O)c1ccc(OC)cc1)(Nc2nc3ccccc3nc2C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J12 compound treatment 734227.0 250000.0 0.52 738118.0 269000.0 0.58 0.7764 0.9982 1981980 ChemDiv1_025906 CC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)N(N=C(c4ccc(cc4)C(C)(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J13 compound treatment 742218.0 258000.0 0.53 736957.0 268000.0 0.58 0.7863 0.9991 1177282 ChemDiv1_025907 COc1cc2C(OC3=C(C(=O)c4ccccc34)c2cc1OC)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J14 compound treatment 720857.0 237000.0 0.49 718580.0 249000.0 0.54 0.727 0.9988 1981981 ChemDiv1_025908 CCCCOCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccc(C)cc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J15 compound treatment 808799.0 325000.0 0.67 839182.0 370000.0 0.8 1.04 0.9961 1981982 ChemDiv1_025909 Clc1c2ccccc2c(c3nc(c([nH]3)c4ccc(Br)cc4)c5ccc(Br)cc5)c6ccccc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J16 compound treatment 725277.0 241000.0 0.5 732672.0 263000.0 0.57 0.755 0.9977 1981983 ChemDiv1_025910 COc1ccc(cc1[N+](=O)[O-])c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J17 compound treatment 739430.0 255000.0 0.53 783290.0 314000.0 0.68 0.8532 0.9921 1780515 ChemDiv1_025911 [O-][N+](=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)c4nc([nH]c4c5ccccc5)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J18 compound treatment 742171.0 258000.0 0.53 730746.0 261000.0 0.57 0.7767 0.9995 1981984 ChemDiv1_025912 CC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4ccc(cc4)C(C)(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J19 compound treatment 727277.0 243000.0 0.5 723835.0 255000.0 0.55 0.7444 0.9989 1981985 ChemDiv1_025913 S(c1ccccc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J20 compound treatment 738186.0 254000.0 0.52 718078.0 249000.0 0.54 0.7515 0.9999 1705477 ChemDiv1_025914 CCOC(=O)c1nnn(c1CN2CCN(CC2)c3ccccn3)c4nonc4N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J21 compound treatment 752407.0 268000.0 0.55 723261.0 254000.0 0.55 0.7802 1.0 1981986 ChemDiv1_025915 CC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J22 compound treatment 725871.0 242000.0 0.5 718393.0 249000.0 0.54 0.7341 0.9992 1981987 ChemDiv1_025916 O=P(COc1ccccc1CP(=O)(c2ccccc2)c3ccccc3)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J23 mock treatment 732528.0 248000.0 0.51 717944.0 249000.0 0.54 0.7431 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 J24 mock treatment 218240.0 -266000.0 -0.55 223256.0 -246000.0 -0.53 -0.7647 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K01 compound treatment 628156.0 144000.0 0.3 599831.0 131000.0 0.28 0.41 0.9997 1981988 ChemDiv1_025917 CCOC(=O)C1=NN(c2ccc(C)cc2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K02 compound treatment 646833.0 163000.0 0.34 636937.0 168000.0 0.36 0.494 0.9992 1981989 ChemDiv1_025918 COc1ccc(cc1F)c2csc(=Nc3cccc(c3)C(F)(F)F)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K03 compound treatment 695349.0 211000.0 0.44 668515.0 199000.0 0.43 0.6132 1.0 1554616 ChemDiv1_025919 CN(C(=O)C1C2CCCC1C2c3ccccc3)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K04 compound treatment 1027182.0 543000.0 1.12 920989.0 452000.0 0.98 1.4839 0.9977 1981990 ChemDiv1_025920 CN(C)c1ccc(cc1)C2N(N=C(N2c3ccc(Cl)c(Cl)c3)C(=O)C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K05 compound treatment 694948.0 211000.0 0.44 684610.0 215000.0 0.47 0.6372 0.9994 1981991 ChemDiv1_025921 COc1ccc(NC2=CC(N(C2=O)c3ccc(OC)cc3)c4cccc5ccccc45)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K06 compound treatment 692893.0 209000.0 0.43 638306.0 169000.0 0.37 0.5633 0.9967 1459888 ChemDiv1_025922 COc1ccc(cc1)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K07 compound treatment 719673.0 235000.0 0.49 734406.0 265000.0 0.57 0.7495 0.9966 1981992 ChemDiv1_025923 CN1C(=O)/C(=C\2/Sc3ccccc3N2c4ccccc4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K08 compound treatment 712143.0 228000.0 0.47 703664.0 234000.0 0.51 0.6915 0.9993 1981993 ChemDiv1_025924 Clc1cccc(c1)N2C(=S)N/C(=N\c3ccccc3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K09 compound treatment 721249.0 237000.0 0.49 687404.0 218000.0 0.47 0.6799 0.9998 1981994 ChemDiv1_025925 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)C4CCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K10 compound treatment 745658.0 261000.0 0.54 758159.0 289000.0 0.63 0.8238 0.9973 1981995 ChemDiv1_025926 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4c5ccccc5c(Cl)c6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K11 compound treatment 742263.0 258000.0 0.53 710769.0 241000.0 0.52 0.7463 1.0 1981996 ChemDiv1_025927 CC(=O)c1ccc(/N=C/2\NC(C)(C)Cc3cc(C)c(C)cc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K12 compound treatment 724504.0 240000.0 0.5 721994.0 253000.0 0.55 0.7376 0.9988 1981997 ChemDiv1_025928 [O-][N+](=O)c1ccc2OC3=CCCCC3=Cc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K13 compound treatment 726440.0 242000.0 0.5 697525.0 228000.0 0.49 0.7029 1.0 1981998 ChemDiv1_025929 CSC1=N/C(=N\c2ccccc2)/C3(CCCCC3)N1c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K14 compound treatment 699319.0 215000.0 0.44 704085.0 235000.0 0.51 0.6734 0.9977 1195272 ChemDiv1_025930 Oc1ccc2oc3CCCC(=O)c3c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K15 compound treatment 693749.0 210000.0 0.43 704424.0 235000.0 0.51 0.6658 0.9967 1981999 ChemDiv1_025931 CCCCC1(CCCC)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K16 compound treatment 698196.0 214000.0 0.44 692168.0 223000.0 0.48 0.6535 0.999 1708071 ChemDiv1_025932 CC(C)C(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)OC6CC(C)CCC6C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K17 compound treatment 721994.0 238000.0 0.49 729151.0 260000.0 0.56 0.7449 0.9977 1152262 ChemDiv1_025933 Clc1cccc(c1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K18 compound treatment 666410.0 182000.0 0.38 681126.0 212000.0 0.46 0.5902 0.9952 1948604 ChemDiv1_025934 CC(C)CCC1(C)NN(C(=S)N1)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K19 compound treatment 742194.0 258000.0 0.53 731167.0 262000.0 0.57 0.7774 0.9995 1982000 ChemDiv1_025935 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc(cc4)C5CCCCC5)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K20 compound treatment 678641.0 194000.0 0.4 718377.0 249000.0 0.54 0.6651 0.9895 1982001 ChemDiv1_025936 CCCCOc1ccc(cc1)C2C=C(Nc3ccc(C)c(C)c3)C(=O)N2c4ccc(C)c(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K21 compound treatment 736328.0 252000.0 0.52 722578.0 253000.0 0.55 0.7557 0.9997 1982002 ChemDiv1_025937 COc1cc2CC(C)(C)N/C(=N\c3ccc(Cl)cc3)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K22 compound treatment 713238.0 229000.0 0.47 711388.0 242000.0 0.52 0.7049 0.9987 1982003 ChemDiv1_025938 CC(C)(C)C1=CC2(Nc3cc(Cl)ccc3OC2c4ccccc4)C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K23 mock treatment 704907.0 221000.0 0.46 698065.0 229000.0 0.5 0.6723 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 K24 mock treatment 245372.0 -239000.0 -0.49 196699.0 -273000.0 -0.59 -0.7658 -0.996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L01 compound treatment 666529.0 182000.0 0.38 610420.0 141000.0 0.31 0.4822 0.9946 1530367 ChemDiv1_025939 COc1ccc(cc1)c2nn(CN3CCC(CC3)c4ccccc4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L02 compound treatment 671067.0 187000.0 0.39 657654.0 188000.0 0.41 0.5611 0.9996 1982004 ChemDiv1_025940 CC(C)(C)C1=CC2(Nc3cc(ccc3OC2c4ccccc4)[N+](=O)[O-])C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L03 compound treatment 679314.0 195000.0 0.4 689024.0 220000.0 0.48 0.6211 0.9966 1982005 ChemDiv1_025941 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cn(Cc5ccccc5)c6ccccc46)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L04 compound treatment 674066.0 190000.0 0.39 695900.0 227000.0 0.49 0.624 0.9938 1982006 ChemDiv1_025942 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccc(C)cc4N(C(=O)C(F)(F)F)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L05 compound treatment 722898.0 239000.0 0.49 710775.0 241000.0 0.52 0.7181 0.9996 1982007 ChemDiv1_025943 CCCC(=O)N1C2CCN(C)CC2c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L06 compound treatment 730055.0 246000.0 0.51 708166.0 239000.0 0.52 0.7245 1.0 1982008 ChemDiv1_025944 COc1cc(ccc1OCc2c(Cl)cccc2Cl)C3N(N=C(N3c4ccccc4)C(=O)C)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L07 compound treatment 719394.0 235000.0 0.49 689132.0 220000.0 0.48 0.6798 0.9999 1610732 ChemDiv1_025945 Clc1ccc(cc1)c2nc([nH]c2c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L08 compound treatment 714463.0 230000.0 0.48 672540.0 203000.0 0.44 0.6472 0.9993 1448632 ChemDiv1_025946 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L09 compound treatment 755724.0 272000.0 0.56 704547.0 235000.0 0.51 0.7564 0.9988 1982009 ChemDiv1_025947 Cc1ccc(C)c(c1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(cc5)[N+](=O)[O-])c6ccccc6)c7ccccc27 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L10 compound treatment 703376.0 219000.0 0.45 697536.0 228000.0 0.49 0.6693 0.999 1982010 ChemDiv1_025948 CCCCCCCCCCCCCCCCCNN=C1CSc2sc(=S)sc2SC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L11 compound treatment 738588.0 254000.0 0.53 727831.0 259000.0 0.56 0.7671 0.9995 1982011 ChemDiv1_025949 [O-][N+](=O)c1ccc(OC/C=C\2/Oc3ccc(cc3C2N4CCOCC4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L12 compound treatment 732906.0 249000.0 0.51 734383.0 265000.0 0.57 0.7688 0.9985 1982012 ChemDiv1_025950 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)N(N=C(c4ccc(cc4)C(C)(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L13 compound treatment 755938.0 272000.0 0.56 683680.0 214000.0 0.46 0.7248 0.9956 1982013 ChemDiv1_025951 CN1CCC2C(C1)c3cc(C)ccc3N2C(=S)Nc4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L14 compound treatment 700400.0 216000.0 0.45 735278.0 266000.0 0.58 0.7227 0.9921 1725848 ChemDiv1_025952 CC(C)COCC1CC2(CC(C)(OC2=O)c3csc(N)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L15 compound treatment 743911.0 260000.0 0.54 756240.0 287000.0 0.62 0.8183 0.9973 1982014 ChemDiv1_025953 OCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L16 compound treatment 729487.0 245000.0 0.51 742406.0 273000.0 0.59 0.7761 0.997 1982015 ChemDiv1_025954 CCCOCC1CC2(CC(C)(OC2=O)c3csc(N)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L17 compound treatment 721557.0 237000.0 0.49 762081.0 293000.0 0.63 0.7946 0.9919 1982016 ChemDiv1_025955 OC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6cc(ccc65)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L18 compound treatment 704434.0 220000.0 0.45 740271.0 271000.0 0.59 0.7362 0.9921 1982017 ChemDiv1_025956 CC(C)CNC(=O)/C(=C/c1cn(nc1c2ccc(Cl)cc2)c3ccccc3)/NC(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L19 compound treatment 740071.0 256000.0 0.53 735784.0 267000.0 0.58 0.7814 0.999 1982018 ChemDiv1_025957 Cc1cccc(c1)N2C(C(=C(O)C2=O)C(=O)c3ccc(Cl)cc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L20 compound treatment 730454.0 246000.0 0.51 714045.0 245000.0 0.53 0.7341 0.9998 1982019 ChemDiv1_025958 Cc1ccc(cc1)C2(SC3(SC(=NN3c4ccccc4)C(=O)c5ccccc5)c6ccccc62)c7ccc(C)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L21 compound treatment 762876.0 279000.0 0.58 765089.0 296000.0 0.64 0.8595 0.9986 1516109 ChemDiv1_025959 Cn1c(Cc2ccccc2)nn(C3CC(=O)C4OCC3O4)c1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L22 compound treatment 722448.0 238000.0 0.49 713206.0 244000.0 0.53 0.7211 0.9994 1982020 ChemDiv1_025960 CN1CCN(CC1)C23CCCCC3=Cc4cc(ccc4O2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L23 mock treatment 704871.0 221000.0 0.46 713898.0 245000.0 0.53 0.6965 0.9972 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 L24 mock treatment 234460.0 -250000.0 -0.52 210585.0 -259000.0 -0.56 -0.7604 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M01 compound treatment 716032.0 232000.0 0.48 629924.0 161000.0 0.35 0.5843 0.9877 1982021 ChemDiv1_025961 CCN(CC)c1ccc(C=c2sc3nnc(c4ccc(C)cc4)n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M02 compound treatment 703659.0 219000.0 0.45 610235.0 141000.0 0.31 0.5361 0.9815 1982022 ChemDiv1_025962 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M03 compound treatment 702803.0 219000.0 0.45 694864.0 226000.0 0.49 0.6644 0.9992 1982023 ChemDiv1_025963 CCOC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M04 compound treatment 658556.0 174000.0 0.36 639432.0 170000.0 0.37 0.5149 0.9999 1982024 ChemDiv1_025964 Cc1ccc2N=C(NN=C(c3ccc(Br)cc3)c2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M05 compound treatment 695429.0 211000.0 0.44 666451.0 197000.0 0.43 0.6101 0.9999 1780527 ChemDiv1_025965 CN(C)c1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M06 compound treatment 683806.0 200000.0 0.41 671880.0 203000.0 0.44 0.6015 0.9995 1586037 ChemDiv1_025966 Clc1ccc(cc1)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M07 compound treatment 728391.0 244000.0 0.5 705521.0 236000.0 0.51 0.718 1.0 1982025 ChemDiv1_025967 CN1C(=O)/C(=C\2/Sc3ccc(Cl)cc3N2C4CCCCC4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M08 compound treatment 690646.0 206000.0 0.43 658544.0 189000.0 0.41 0.591 0.9998 1982026 ChemDiv1_025968 CCOC(=O)CN1C(=S)N/C(=N\c2ccccc2)/C31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M09 compound treatment 733830.0 250000.0 0.52 681247.0 212000.0 0.46 0.6888 0.9983 1982027 ChemDiv1_025969 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)C4CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M10 compound treatment 702466.0 218000.0 0.45 659650.0 190000.0 0.41 0.61 0.999 1642193 ChemDiv1_025970 CC1COc2c(N3CCN(C)CC3)c(F)cc4c(=O)c(cn1c24)C(=O)Nc5ccc(F)c(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M11 compound treatment 711791.0 228000.0 0.47 662571.0 193000.0 0.42 0.6281 0.9983 1982028 ChemDiv1_025971 Clc1cc(Cl)cc(/N=C/2\NC3(CCCCC3)Cc4ccccc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M12 compound treatment 709943.0 226000.0 0.47 679941.0 211000.0 0.46 0.652 0.9999 1982029 ChemDiv1_025972 FC(F)(F)c1cccc(N=c2scc(c3ccc(Cl)cc3)n2CCc4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M13 compound treatment 725358.0 241000.0 0.5 688429.0 219000.0 0.47 0.6874 0.9997 1982030 ChemDiv1_025973 Clc1ccc(cc1)N2C(=S)N/C(=N\c3ccccc3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M14 compound treatment 725446.0 241000.0 0.5 699548.0 230000.0 0.5 0.7046 1.0 1228741 ChemDiv1_025974 COc1ccc2oc3C(=NCC(=O)Nc3c2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M15 compound treatment 729746.0 246000.0 0.51 697833.0 229000.0 0.49 0.7082 0.9999 1982031 ChemDiv1_025975 CCOc1ccc(NC2=CC(N(C2=O)c3ccc(OCC)cc3)c4ccc(cc4)C(C)(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M16 compound treatment 683946.0 200000.0 0.41 687121.0 218000.0 0.47 0.625 0.9978 1982032 ChemDiv1_025976 Cc1cccc(C)c1n2nnnc2C3(CCCCC3)N4CCCC4C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M17 compound treatment 736379.0 252000.0 0.52 689575.0 220000.0 0.48 0.7053 0.999 1294449 ChemDiv1_025977 CCOC(=O)C1C(NC(=S)NC1(O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M18 compound treatment 696900.0 213000.0 0.44 691423.0 222000.0 0.48 0.6505 0.999 1982033 ChemDiv1_025978 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5ccc6C(=O)OCc6c5)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M19 compound treatment 715714.0 232000.0 0.48 697903.0 229000.0 0.49 0.6879 0.9998 1982034 ChemDiv1_025979 Cc1ccc(C)c(c1)c2csc(=Nc3ccc(F)cc3)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M20 compound treatment 709092.0 225000.0 0.46 678055.0 209000.0 0.45 0.6478 0.9999 1982035 ChemDiv1_025980 CCCCOc1ccc(cc1)C2C=C(Nc3ccc(CC)cc3)C(=O)N2c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M21 compound treatment 736423.0 252000.0 0.52 718425.0 249000.0 0.54 0.7495 0.9998 1982036 ChemDiv1_025981 COc1cc2CC(C)(C)N/C(=N\c3ccc(F)c(F)c3)/c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M22 compound treatment 705170.0 221000.0 0.46 690978.0 222000.0 0.48 0.6619 0.9997 1982037 ChemDiv1_025982 CC(C)(C)C1=CC2(Nc3cc(Br)ccc3OC2C=C)C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M23 mock treatment 719384.0 235000.0 0.49 669512.0 200000.0 0.43 0.6498 0.9984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 M24 mock treatment 390541.0 -93600.0 -0.19 383064.0 -86200.0 -0.19 -0.2686 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N01 compound treatment 754083.0 270000.0 0.56 714309.0 245000.0 0.53 0.769 0.9997 1409191 ChemDiv1_025983 CCOc1cc(C=c2sc3=C(C#N)C(C(=C(N)n3c2=O)C#N)c4ccc(OC)c(OCC)c4)ccc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N02 compound treatment 681285.0 197000.0 0.41 655140.0 186000.0 0.4 0.5722 1.0 1982038 ChemDiv1_025984 CC(C)(C)C1=CC2(Nc3ccc(cc3OC2c4ccccc4)[N+](=O)[O-])C=C(C1=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N03 compound treatment 702502.0 218000.0 0.45 688184.0 219000.0 0.47 0.6537 0.9997 1982039 ChemDiv1_025985 Cc1ccc(cc1)S(=O)(=O)Oc2ccc3c(OC(CC43CC(C)(C)NC(=S)N4)c5ccccc5)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N04 compound treatment 677469.0 193000.0 0.4 674161.0 205000.0 0.44 0.5957 0.9986 1982040 ChemDiv1_025986 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(OCC)ccc4N(C(=O)Cc5ccccc5)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N05 compound treatment 706450.0 222000.0 0.46 700075.0 231000.0 0.5 0.6777 0.9991 1982041 ChemDiv1_025987 [O-][N+](=O)c1ccc(cc1)C2Nc3c(Cl)cc(Cl)cc3C4C(Cl)C(CC42)Sc5ccccc5[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N06 compound treatment 792384.0 308000.0 0.64 877200.0 408000.0 0.88 1.0742 0.9871 1982042 ChemDiv1_025988 COc1ccc(cc1)N2C(N(N=C2C(=O)C)c3ccccc3)c4cccc(OCc5ccc(Cl)cc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N07 compound treatment 714373.0 230000.0 0.48 705831.0 237000.0 0.51 0.698 0.9993 1524477 ChemDiv1_025989 CCCS(=O)(=O)c1c(C(=O)c2ccc(C)cc2C)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N08 compound treatment 687282.0 203000.0 0.42 675076.0 206000.0 0.45 0.6114 0.9995 1188273 ChemDiv1_025990 Cc1ccc(cc1)n2c(=O)c3c([nH]c2=S)-c4ccccc4CC53CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N09 compound treatment 711739.0 228000.0 0.47 715592.0 246000.0 0.53 0.7091 0.998 1982043 ChemDiv1_025991 CC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N10 compound treatment 692853.0 209000.0 0.43 677754.0 208000.0 0.45 0.6237 0.9997 1184642 ChemDiv1_025992 CC1(C)OC(=O)N(CC(=O)O)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N11 compound treatment 707331.0 223000.0 0.46 702542.0 233000.0 0.5 0.6827 0.999 1982044 ChemDiv1_025993 OC(C(=O)NN(C(=O)c1ccccc1F)c2ccccc2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N12 compound treatment 659740.0 176000.0 0.36 619917.0 151000.0 0.33 0.4868 0.9986 1982045 ChemDiv1_025994 Cc1cc2N(C(=O)C=C)C(C)(C)c3ssc(=S)c3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N13 compound treatment 735358.0 251000.0 0.52 707238.0 238000.0 0.52 0.7308 1.0 1982046 ChemDiv1_025995 COc1ccc(cc1)N2C(=S)N/C(=N\c3ccccc3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N14 compound treatment 915789.0 432000.0 0.89 869541.0 400000.0 0.87 1.2426 0.9999 1982047 ChemDiv1_025996 CC(=O)C1=NN(C(N1C(C)(C)C)c2ccccc2OCc3ccc(Cl)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N15 compound treatment 728117.0 244000.0 0.5 745025.0 276000.0 0.6 0.7781 0.9964 1982048 ChemDiv1_025997 [O-][N+](=O)c1cccc(C=c2sc3nnc(c4ccccc4Cl)n3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N16 compound treatment 646633.0 162000.0 0.34 624870.0 156000.0 0.34 0.4753 1.0 1982049 ChemDiv1_025998 CCCCN(CCCC)Cc1c(nnn1c2nonc2N)C(=O)OC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N17 compound treatment 761203.0 277000.0 0.57 734132.0 265000.0 0.57 0.8097 1.0 1149062 ChemDiv1_025999 Cc1onc(c1C(=O)Nc2sc3CCCCc3c2C#N)c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N18 compound treatment 726073.0 242000.0 0.5 718211.0 249000.0 0.54 0.7341 0.9993 1982050 ChemDiv1_026000 CC1=NN(C(=O)C1C(C(C#N)C#N)c2ccccc2Cl)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N19 compound treatment 737538.0 253000.0 0.52 714177.0 245000.0 0.53 0.7446 1.0 1159075 ChemDiv1_026001 CC(C)Sc1nnc2c3ccccc3n(CCc4ccccc4)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N20 compound treatment 715183.0 231000.0 0.48 699568.0 230000.0 0.5 0.6896 0.9998 1982051 ChemDiv1_026002 CC(=O)C1=NN(c2ccccc2C)C3(S1)SC(c4ccccc43)(c5ccccc5C)c6ccccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N21 compound treatment 747929.0 264000.0 0.54 732761.0 263000.0 0.57 0.7882 0.9997 1982052 ChemDiv1_026003 CC(C)(NCCNC(C)(C)P(=O)(O)O)P(=O)(O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N22 compound treatment 694938.0 211000.0 0.44 675081.0 206000.0 0.45 0.6226 0.9999 1784371 ChemDiv1_026004 [O-][N+](=O)c1cccc2C=C3CCCCC3(Oc12)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N23 mock treatment 708171.0 224000.0 0.46 690192.0 221000.0 0.48 0.6651 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 N24 mock treatment 380781.0 -103000.0 -0.21 393075.0 -76200.0 -0.16 -0.2676 -0.9919 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O01 compound treatment 649475.0 165000.0 0.34 599172.0 130000.0 0.28 0.4401 0.9954 1945254 ChemDiv1_026005 COc1ccc(C=c2sc3nnc(c4ccc(C)cc4)n3c2=O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O02 compound treatment 641080.0 157000.0 0.32 594013.0 125000.0 0.27 0.4199 0.9959 1982053 ChemDiv1_026006 Cc1cn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)nc1N5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O03 compound treatment 686388.0 202000.0 0.42 632524.0 163000.0 0.35 0.545 0.9966 1982054 ChemDiv1_026007 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O04 compound treatment 657054.0 173000.0 0.36 635147.0 166000.0 0.36 0.5062 1.0 1517464 ChemDiv1_026008 CCCS(=O)(=O)c1c(C(=O)c2cc(C)ccc2C)n3cc(C)cc(C)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O05 compound treatment 688022.0 204000.0 0.42 622564.0 153000.0 0.33 0.5321 0.9931 1982055 ChemDiv1_026009 Brc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O06 compound treatment 654576.0 170000.0 0.35 641003.0 172000.0 0.37 0.5115 0.9996 1982056 ChemDiv1_026010 CC(=O)C1=NN(c2cccc(Cl)c2C)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O07 compound treatment 702567.0 218000.0 0.45 660856.0 192000.0 0.41 0.612 0.9991 1982057 ChemDiv1_026011 CCN1C(=O)/C(=C\2/Sc3ccccc3N2C4CCCCC4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O08 compound treatment 677098.0 193000.0 0.4 660300.0 191000.0 0.41 0.5739 0.9998 1982058 ChemDiv1_026012 [O-][N+](=O)c1ccc2OC3(CCCCC3=Cc2c1)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O09 compound treatment 729229.0 245000.0 0.51 662166.0 193000.0 0.42 0.6529 0.9954 1982059 ChemDiv1_026013 CC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)SC(c4ccccc43)(c5ccc(C)cc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O10 compound treatment 673028.0 189000.0 0.39 647683.0 178000.0 0.39 0.5487 1.0 1239211 ChemDiv1_026014 CCC1(CC)Cc2ccccc2C(=C3C(=O)CC(C)(C)CC3=O)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O11 compound treatment 689566.0 205000.0 0.42 652937.0 184000.0 0.4 0.5809 0.9995 1982060 ChemDiv1_026015 CCOC(=O)C1(C)C=C(Nc2ccc(OCC)cc2)C(=O)N1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O12 compound treatment 672990.0 189000.0 0.39 663368.0 194000.0 0.42 0.5726 0.9993 1265219 ChemDiv1_026016 CC1(C)c2ccccc2N(CC(=O)NCC=C)C31Oc4ccc5ccccc5c4C=C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O13 compound treatment 713866.0 230000.0 0.47 689659.0 220000.0 0.48 0.6726 1.0 1982061 ChemDiv1_026017 OC(=O)c1cccc(c1)N2C(=S)N/C(=N\c3ccccc3)/C42CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O14 compound treatment 679917.0 196000.0 0.4 636378.0 167000.0 0.36 0.5415 0.9985 1406553 ChemDiv1_026018 Cc1ccc(NC(=O)Cc2[nH]c3ccccc3c2Sc4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O15 compound treatment 736271.0 252000.0 0.52 719851.0 251000.0 0.54 0.7515 0.9998 1982062 ChemDiv1_026019 CC1(C2C(C(=O)N(C2=O)c3ccccc3Br)C4(C=O)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O16 compound treatment 698884.0 215000.0 0.44 633504.0 164000.0 0.36 0.5647 0.994 1982063 ChemDiv1_026020 COc1cc(ccc1OCc2cc3OCOc3cc2Cl)C4Nc5ccc6ccccc6c5C7=C4C(=O)CC(C)(C)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O17 compound treatment 731994.0 248000.0 0.51 699188.0 230000.0 0.5 0.7136 0.9999 1982064 ChemDiv1_026021 COc1ccc(cc1N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O18 compound treatment 684868.0 201000.0 0.41 685544.0 216000.0 0.47 0.6239 0.9981 1982065 ChemDiv1_026022 COc1cc(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)ccc1OCc6ccc(Cl)cc6Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O19 compound treatment 745773.0 262000.0 0.54 683161.0 214000.0 0.46 0.7092 0.9971 1982066 ChemDiv1_026023 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4cc(C)ccc4C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O20 compound treatment 724314.0 240000.0 0.5 676510.0 207000.0 0.45 0.6677 0.9988 1982067 ChemDiv1_026024 CCCCOc1ccc(cc1)C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O21 compound treatment 728424.0 244000.0 0.5 673337.0 204000.0 0.44 0.6688 0.9978 1982068 ChemDiv1_026025 Fc1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc(Sc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O22 compound treatment 701199.0 217000.0 0.45 684586.0 215000.0 0.47 0.6463 0.9998 1508187 ChemDiv1_026026 Clc1cccc(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O23 mock treatment 692003.0 208000.0 0.43 661749.0 192000.0 0.42 0.5979 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 O24 mock treatment 408028.0 -76100.0 -0.16 413610.0 -55700.0 -0.12 -0.1964 -0.9914 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P01 compound treatment 611437.0 127000.0 0.26 585283.0 116000.0 0.25 0.3633 0.9997 1982069 ChemDiv1_026027 COc1cc(ccc1OCc2c(F)cccc2Cl)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P02 compound treatment 625311.0 141000.0 0.29 601697.0 132000.0 0.29 0.4087 1.0 1982070 ChemDiv1_026028 [O-][N+](=O)c1ccc2O/C(=C/COc3ccc(Cl)cc3Cl)/C(N4CCOCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P03 compound treatment 654745.0 171000.0 0.35 603681.0 134000.0 0.29 0.4547 0.9955 1437718 ChemDiv1_026029 CC1(CC(c2ccccc2)C3(C#N)C(=N)O1)C3(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P04 compound treatment 649042.0 165000.0 0.34 607519.0 138000.0 0.3 0.4522 0.9979 1982071 ChemDiv1_026030 Cc1ccc2NC(C)(C)c3sn(c4ccc(cc4)C(F)(F)F)c(=S)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P05 compound treatment 651004.0 167000.0 0.34 608791.0 140000.0 0.3 0.457 0.9979 1982072 ChemDiv1_026031 [O-][N+](=O)c1ccc2NC(C3CC(Sc4ccccc4[N+](=O)[O-])C(Cl)C3c2c1)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P06 compound treatment 768421.0 284000.0 0.59 810627.0 341000.0 0.74 0.9373 0.9935 1982073 ChemDiv1_026032 COc1cc(ccc1OCc2ccc(Cl)cc2)C3N(N=C(N3c4ccccc4)C(=O)C)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P07 compound treatment 660165.0 176000.0 0.36 631936.0 163000.0 0.35 0.5058 0.9999 1652382 ChemDiv1_026033 CCCS(=O)(=O)c1c(C(=O)c2ccc(CC)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P08 compound treatment 667378.0 183000.0 0.38 610884.0 142000.0 0.31 0.4841 0.9946 1982074 ChemDiv1_026034 CCOC(=O)C1=NN(c2ccc(Cl)cc2)C3(S1)N(N=C(c4ccc(cc4)C(C)(C)C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P09 compound treatment 639202.0 155000.0 0.32 627222.0 158000.0 0.34 0.468 0.9995 1982075 ChemDiv1_026035 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)N(N=C(c4cc(C)ccc4C)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P10 compound treatment 663975.0 180000.0 0.37 655550.0 186000.0 0.4 0.5475 0.9991 1982076 ChemDiv1_026036 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)cc5[N+](=O)[O-])c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P11 compound treatment 665185.0 181000.0 0.37 622046.0 153000.0 0.33 0.498 0.9981 1982077 ChemDiv1_026037 Clc1cccc(C=c2sc3nnc(c4ccccc4)n3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P12 compound treatment 697510.0 213000.0 0.44 668265.0 199000.0 0.43 0.6159 0.9999 1780819 ChemDiv1_026038 Fc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5ccc(Cl)c(Cl)c5)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P13 compound treatment 681227.0 197000.0 0.41 638771.0 169000.0 0.37 0.547 0.9987 1159778 ChemDiv1_026039 Cc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P14 compound treatment 670931.0 187000.0 0.39 631469.0 162000.0 0.35 0.5208 0.9989 1982078 ChemDiv1_026040 CCCCOCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P15 compound treatment 693929.0 210000.0 0.43 649160.0 180000.0 0.39 0.5815 0.9986 1982079 ChemDiv1_026041 COc1ccc(C=c2sc3nnc(c4ccccc4Cl)n3c2=O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P16 compound treatment 679429.0 195000.0 0.4 660042.0 191000.0 0.41 0.577 0.9999 1982080 ChemDiv1_026042 CC1(C)Cc2ccccc2/C(=C/C(=O)N)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P17 compound treatment 700772.0 217000.0 0.45 674270.0 205000.0 0.44 0.6299 1.0 1982081 ChemDiv1_026043 Brc1ccc(cc1)c2nc(c([nH]2)c3ccccc3Br)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P18 compound treatment 697742.0 214000.0 0.44 654084.0 185000.0 0.4 0.5946 0.9988 1982082 ChemDiv1_026044 CC1=NN(C(=O)C1C(C(C#N)C#N)c2cccc(Cl)c2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P19 compound treatment 680824.0 197000.0 0.41 655795.0 187000.0 0.4 0.5725 1.0 1780525 ChemDiv1_026045 [O-][N+](=O)c1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc(Oc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P20 compound treatment 731600.0 247000.0 0.51 631147.0 162000.0 0.35 0.6089 0.9831 1982083 ChemDiv1_026046 Clc1ccc(cc1)C2(SC3(SC(=NN3c4ccccc4)C(=O)c5ccccc5)c6ccccc62)c7ccc(Cl)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P21 compound treatment 687160.0 203000.0 0.42 652757.0 183000.0 0.4 0.5771 0.9996 1661694 ChemDiv1_026047 COc1ccc(CCNC(=O)C2(C)CC3c4ccccc4C2c5ccccc35)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P22 compound treatment 669377.0 185000.0 0.38 641037.0 172000.0 0.37 0.5332 0.9999 1528830 ChemDiv1_026048 CN1CCC(OC(=O)C)(c2ccccc2)C(C)(C)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P23 mock treatment 643378.0 159000.0 0.33 625972.0 157000.0 0.34 0.4722 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.660 P24 mock treatment 451088.0 -33100.0 -0.07 471727.0 2440.0 0.01 -0.0446 -0.6504 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A01 compound treatment 623921.0 143000.0 0.3 566670.0 109000.0 0.24 0.3763 0.9938 1590592 ChemDiv1_026049 CCC1CN(C)CCC1(OC(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A02 compound treatment 611426.0 131000.0 0.27 570405.0 113000.0 0.24 0.3638 0.9988 1307000 ChemDiv1_026050 COc1cccc(c1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A03 compound treatment 676832.0 196000.0 0.41 592255.0 135000.0 0.29 0.4927 0.987 1982084 ChemDiv1_026051 Cc1c(oc2c(C)c3oc(=O)cc(C)c3cc12)/C(=N/O)/c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A04 compound treatment 654319.0 174000.0 0.36 585021.0 128000.0 0.28 0.4488 0.9916 1982085 ChemDiv1_026052 Cc1ccc(cc1C)S(=O)(=O)n2nnc3cc(Cl)ccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A05 compound treatment 635787.0 155000.0 0.32 592703.0 135000.0 0.29 0.4335 0.999 1563932 ChemDiv1_026053 COc1ccc(cc1)C2(Oc3ccccc3C(=C2C)C#Cc4ccccc4)N5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A06 compound treatment 665417.0 185000.0 0.38 612932.0 155000.0 0.34 0.5077 0.998 1253856 ChemDiv1_026054 COC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN4CCCCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A07 compound treatment 676960.0 196000.0 0.41 630010.0 173000.0 0.37 0.5507 0.9992 1982086 ChemDiv1_026055 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A08 compound treatment 684081.0 203000.0 0.42 653238.0 196000.0 0.42 0.5966 1.0 1151411 ChemDiv1_026056 NC1=C(C#N)C2=CCCCC2C(c3cccc(Oc4ccccc4)c3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A09 compound treatment 670866.0 190000.0 0.39 631164.0 174000.0 0.38 0.5435 0.9998 1982087 ChemDiv1_026057 NS(=O)(=O)c1ccc(CCn2c(csc2=Nc3ccc(OC(F)(F)Cl)cc3)c4ccc(Cl)s4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A10 compound treatment 694953.0 214000.0 0.44 647549.0 190000.0 0.41 0.6038 0.9993 1982088 ChemDiv1_026058 COc1cc(ccc1OCc2ccc(Cl)cc2)C3N(N=C(N3c4ccc(cc4)N5CCOCC5)C(=O)C)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A11 compound treatment 649864.0 169000.0 0.35 640531.0 183000.0 0.4 0.5272 0.998 1982089 ChemDiv1_026059 CC(=O)C1=C(O)C(=O)N(C1c2ccc3OCOc3c2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A12 compound treatment 696262.0 216000.0 0.45 636198.0 179000.0 0.39 0.5883 0.9975 1645841 ChemDiv1_026060 COc1ccc(cc1)C(=O)C2=C(O)C(=O)NC2c3ccc(OC)cc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A13 compound treatment 702307.0 222000.0 0.46 634020.0 177000.0 0.38 0.5938 0.996 1982090 ChemDiv1_026061 CCC(=O)N(C)C1(CCC(C)CC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A14 compound treatment 657372.0 177000.0 0.36 657130.0 200000.0 0.43 0.5636 0.9965 1742914 ChemDiv1_026062 Cc1ccsc1C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A15 compound treatment 764937.0 284000.0 0.59 765933.0 308000.0 0.67 0.8871 0.9979 1485914 ChemDiv1_026063 CCCOc1ccc(cc1OCC)C2C3CN(C)CC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A16 compound treatment 676211.0 196000.0 0.4 624700.0 167000.0 0.36 0.5414 0.9985 1982091 ChemDiv1_026064 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)ccc4N(C(=O)C(C)C)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A17 compound treatment 681276.0 201000.0 0.41 644323.0 187000.0 0.4 0.5789 0.9999 1380277 ChemDiv1_026065 Cc1cc(=O)oc2c(C)c3oc(C(=O)c4ccc(Cl)cc4)c(c5ccccc5)c3cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A18 compound treatment 668422.0 188000.0 0.39 643443.0 186000.0 0.4 0.5587 0.9998 1639712 ChemDiv1_026066 CN1C(=O)OC2(CCCCC2)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A19 compound treatment 671973.0 191000.0 0.4 639864.0 182000.0 0.39 0.5585 1.0 1193224 ChemDiv1_026067 COc1ccc(cc1)C2(CC(NC(=S)N2)c3ccco3)c4ccc(O)cc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A20 compound treatment 676117.0 196000.0 0.4 593256.0 136000.0 0.29 0.4932 0.9878 1982092 ChemDiv1_026068 CC(C)CC1C(=C(NC(=C1C(=O)C)C)SCC(=O)Nc2ccc(Br)cc2)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A21 compound treatment 798573.0 318000.0 0.66 702639.0 245000.0 0.53 0.8393 0.9944 1982093 ChemDiv1_026069 CCOC(=O)C(NC(=O)c1ccc(F)cc1)(Nc2sc3CCCCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A22 compound treatment 640819.0 160000.0 0.33 568131.0 111000.0 0.24 0.4032 0.9874 1782232 ChemDiv1_026070 Cc1ccc(cc1C)c2nc([nH]c2c3ccccc3)c4ccc(cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A23 mock treatment 603938.0 123000.0 0.25 554289.0 96800.0 0.21 0.3282 0.9953 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 A24 mock treatment 222742.0 -258000.0 -0.53 282368.0 -175000.0 -0.38 -0.6444 -0.9862 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B01 compound treatment 670181.0 190000.0 0.39 577743.0 120000.0 0.26 0.4608 0.9803 1982094 ChemDiv1_026071 CCN1/C(=C\2/SC(=S)N(CC=C)C2=O)/Sc3ccc(OC)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B02 compound treatment 627666.0 147000.0 0.3 574493.0 117000.0 0.25 0.3937 0.9959 1870721 ChemDiv1_026072 Cc1ccc2N(C(=O)Nc3cccc(Cl)c3)C(C)(C)CC(C)(c4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B03 compound treatment 731522.0 251000.0 0.52 642505.0 185000.0 0.4 0.6494 0.9919 1982095 ChemDiv1_026073 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccc(OC)cc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B04 compound treatment 783862.0 303000.0 0.63 712453.0 255000.0 0.55 0.8329 0.998 1982096 ChemDiv1_026074 CCOC(=O)c1cc2/C(=N\NC(=S)N)/c3ccccc3-c2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B05 compound treatment 729779.0 249000.0 0.51 658821.0 201000.0 0.44 0.6718 0.9966 1631279 ChemDiv1_026075 Cc1c(oc2c(C)c3oc(=O)cc(C)c3cc12)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B06 compound treatment 729450.0 249000.0 0.51 656518.0 199000.0 0.43 0.6678 0.9962 1982097 ChemDiv1_026076 COc1ccc(cc1)C(C(=O)NN(C)c2ccccc2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B07 compound treatment 761467.0 281000.0 0.58 677022.0 220000.0 0.48 0.746 0.9951 1982098 ChemDiv1_026077 CC(=O)C1=NN(c2ccccc2C)C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B08 compound treatment 741140.0 261000.0 0.54 695063.0 238000.0 0.51 0.7439 0.9997 1982099 ChemDiv1_026078 CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B09 compound treatment 775267.0 295000.0 0.61 684528.0 227000.0 0.49 0.7776 0.9944 1537114 ChemDiv1_026079 CC1CC(=O)N(Cc2ccccc2)c3ccccc3N1C=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B10 compound treatment 742800.0 262000.0 0.54 684280.0 227000.0 0.49 0.7298 0.9988 1380331 ChemDiv1_026080 CCCS(=O)(=O)c1c(C(=O)c2ccc(Br)cc2)n3cccc(C(=O)N)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B11 compound treatment 764767.0 284000.0 0.59 702445.0 245000.0 0.53 0.7897 0.9987 1949022 ChemDiv1_026081 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B12 compound treatment 745571.0 265000.0 0.55 664862.0 207000.0 0.45 0.7041 0.9952 1184314 ChemDiv1_026082 OC(=O)CCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B13 compound treatment 798183.0 318000.0 0.66 697465.0 240000.0 0.52 0.8308 0.9933 1415916 ChemDiv1_026083 CCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cc(Cl)ccc5C)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B14 compound treatment 752343.0 272000.0 0.56 693904.0 236000.0 0.51 0.7585 0.9989 1213142 ChemDiv1_026084 CCOC(=O)c1ccc(cc1)N2C(=O)C(=C(C(=O)c3ccccc3)C2(O)C(=O)OC)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B15 compound treatment 763956.0 283000.0 0.58 719808.0 262000.0 0.57 0.8151 0.9999 1602397 ChemDiv1_026085 CCCc1ccc(OC(C)C(=O)Nc2sc3CCCCCc3c2C#N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B16 compound treatment 749323.0 269000.0 0.55 673921.0 216000.0 0.47 0.7235 0.9965 1589244 ChemDiv1_026086 OC1=C(C(N(C1=O)c2cccc(Cl)c2)c3ccc4OCOc4c3)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B17 compound treatment 788770.0 308000.0 0.64 714352.0 257000.0 0.56 0.8429 0.9977 1982100 ChemDiv1_026087 CC(C)(C)c1ccc(cc1)c2nnc3sc(=Cc4ccccc4)c(=O)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B18 compound treatment 6692052.0 6210000.0 12.82 6736899.0 6280000.0 13.59 18.6771 0.9996 1580886 ChemDiv1_026088 Cc1c(nc2nc(c3ccccc3)c(nn12)c4ccccc4)c5ccc(O)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B19 compound treatment 747704.0 267000.0 0.55 690458.0 233000.0 0.5 0.7464 0.999 1300332 ChemDiv1_026089 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3cccnc3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B20 compound treatment 723135.0 243000.0 0.5 652232.0 195000.0 0.42 0.6521 0.9963 1401148 ChemDiv1_026090 COc1ccc2n(C)c(CC(=O)Nc3cccc(Cl)c3)c(Sc4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B21 compound treatment 730199.0 250000.0 0.52 672011.0 215000.0 0.46 0.6926 0.9986 1264713 ChemDiv1_026091 CCc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B22 compound treatment 853589.0 373000.0 0.77 761515.0 304000.0 0.66 1.0097 0.9969 1982101 ChemDiv1_026092 COc1ccc(CC2N(C)CCc3cc(OC)c(OC)cc23)c(Oc4cc5CC6CN(C)Cc7cc(OC)c(O)c(-c5cc4OC)c67)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B23 mock treatment 692018.0 211000.0 0.44 630767.0 173000.0 0.38 0.5738 0.9971 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 B24 mock treatment 228512.0 -252000.0 -0.52 186018.0 -271000.0 -0.59 -0.7834 -0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C01 compound treatment 661340.0 181000.0 0.37 584231.0 127000.0 0.27 0.4578 0.9885 1209744 ChemDiv1_026093 CN1CCC(OC(=O)c2ccccc2)(c3ccccc3)C(C)(C)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C02 compound treatment 650022.0 169000.0 0.35 643773.0 186000.0 0.4 0.5324 0.9975 1369431 ChemDiv1_026094 Clc1ccc(cc1Cl)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C03 compound treatment 701353.0 221000.0 0.46 641352.0 184000.0 0.4 0.6036 0.9977 1982102 ChemDiv1_026095 CC(=O)c1oc2c(C)c3oc(=O)cc(C)c3cc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C04 compound treatment 695841.0 215000.0 0.44 636941.0 179000.0 0.39 0.5888 0.9977 1782950 ChemDiv1_026096 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C05 compound treatment 742348.0 262000.0 0.54 667054.0 210000.0 0.45 0.7028 0.9962 1332468 ChemDiv1_026097 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(Cl)cc3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C06 compound treatment 729840.0 249000.0 0.51 672869.0 215000.0 0.47 0.6934 0.9988 1262639 ChemDiv1_026098 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C07 compound treatment 737391.0 257000.0 0.53 695249.0 238000.0 0.51 0.7387 0.9999 1982103 ChemDiv1_026099 CC(=O)C1=NN(c2ccccc2C)C3(S1)SC(c4ccccc43)(c5ccc(Cl)cc5)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C08 compound treatment 737814.0 257000.0 0.53 692415.0 235000.0 0.51 0.735 0.9998 1982104 ChemDiv1_026100 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C09 compound treatment 762315.0 282000.0 0.58 707071.0 250000.0 0.54 0.7932 0.9993 1982105 ChemDiv1_026101 COc1ccc(cc1F)c2csc(=Nc3ccc(OC(F)(F)Cl)cc3)n2CCc4ccc(cc4)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C10 compound treatment 731295.0 251000.0 0.52 659096.0 202000.0 0.44 0.6745 0.9964 1982106 ChemDiv1_026102 CCN(CC)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C11 compound treatment 989295.0 509000.0 1.05 942476.0 485000.0 1.05 1.4848 1.0 1982107 ChemDiv1_026103 CC(=O)C1=NN(C(N1C(C)(C)C)c2cccc(OCc3ccc(Cl)cc3)c2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C12 compound treatment 796497.0 316000.0 0.65 769886.0 312000.0 0.68 0.9392 0.9998 1982108 ChemDiv1_026104 Oc1ccc(C=c2sc3=NN=C(C(c4ccccc4)n3c2=O)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C13 compound treatment 743149.0 263000.0 0.54 710559.0 253000.0 0.55 0.7705 1.0 1404367 ChemDiv1_026105 Cc1ccc(cc1C)c2nc([nH]c2c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C14 compound treatment 755630.0 275000.0 0.57 714648.0 257000.0 0.56 0.795 1.0 1982109 ChemDiv1_026106 COC(=O)C12Nc3ccccc3NC(=C2C(=O)C(=O)N1c4cccc(c4)C(F)(F)F)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C15 compound treatment 758540.0 278000.0 0.57 727124.0 270000.0 0.58 0.8184 1.0 1157442 ChemDiv1_026107 COc1ccc(cc1)C2NC(=S)NC(=C2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C16 compound treatment 751218.0 271000.0 0.56 720286.0 263000.0 0.57 0.7972 1.0 1982110 ChemDiv1_026108 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cccc(OC)c4N(C(=O)C=C)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C17 compound treatment 763141.0 283000.0 0.58 720248.0 263000.0 0.57 0.8146 0.9999 1423309 ChemDiv1_026109 COc1cccc(c1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C18 compound treatment 732116.0 252000.0 0.52 711078.0 254000.0 0.55 0.7552 0.9996 1982111 ChemDiv1_026110 [O-][N+](=O)c1cccc(c1)C2NC(C(C(=O)C2c3ccccc3)c4ccccc4)c5cccc(c5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C19 compound treatment 791974.0 311000.0 0.64 719335.0 262000.0 0.57 0.8552 0.998 1588756 ChemDiv1_026111 CC(=O)Oc1cc2OC(CC3(CC(C)(C)NC(=S)N3)c2cc1Cl)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C20 compound treatment 708380.0 228000.0 0.47 691567.0 234000.0 0.51 0.6907 0.9993 1314051 ChemDiv1_026112 CCN1C(=S)N(CC)C2(O)c3ccccc3C(=O)C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C21 compound treatment 738125.0 258000.0 0.53 705495.0 248000.0 0.54 0.7555 1.0 1945233 ChemDiv1_026113 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3ccccc3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C22 compound treatment 704069.0 223000.0 0.46 662926.0 205000.0 0.44 0.6406 0.9998 1982112 ChemDiv1_026114 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C23 mock treatment 683481.0 203000.0 0.42 636874.0 179000.0 0.39 0.5707 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 C24 mock treatment 214993.0 -266000.0 -0.55 209768.0 -248000.0 -0.54 -0.7668 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D01 compound treatment 665629.0 185000.0 0.38 591558.0 134000.0 0.29 0.4753 0.9908 1345824 ChemDiv1_026115 CCCN1C(=O)C(=c2sc(=C3C=Cc4ccccc4N3CC)c(=O)n2Cc5ccccc5)SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D02 compound treatment 643220.0 163000.0 0.34 631696.0 174000.0 0.38 0.504 0.9983 1870724 ChemDiv1_026116 Cc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4ccc(cc4)c5ccccc5)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D03 compound treatment 698500.0 218000.0 0.45 626309.0 169000.0 0.37 0.5764 0.9947 1982113 ChemDiv1_026117 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D04 compound treatment 766054.0 285000.0 0.59 716250.0 259000.0 0.56 0.8127 0.9997 1982114 ChemDiv1_026118 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccc(cc3)N(C)C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D05 compound treatment 746263.0 266000.0 0.55 684557.0 227000.0 0.49 0.7353 0.9985 1458472 ChemDiv1_026119 Cc1cc(=O)oc2c(C)c3oc(C(O)c4ccccc4)c(c5ccccc5)c3cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D06 compound treatment 717075.0 236000.0 0.49 627711.0 170000.0 0.37 0.6057 0.9904 1659882 ChemDiv1_026120 OC(=O)c1c2Cc3ccccc3-c2nc4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D07 compound treatment 766658.0 286000.0 0.59 704095.0 247000.0 0.53 0.795 0.9987 1982115 ChemDiv1_026121 CCc1ccc(cc1)C2(SC3(SC(=NN3c4ccc(cc4)[N+](=O)[O-])C(=O)C)c5ccccc52)c6ccc(CC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D08 compound treatment 778978.0 298000.0 0.62 730040.0 273000.0 0.59 0.8527 0.9998 1982116 ChemDiv1_026122 CCCCN1/C(=C\2/SC(=S)N(CC)C2=O)/Sc3ccc(OC)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D09 compound treatment 787630.0 307000.0 0.63 718725.0 261000.0 0.57 0.848 0.9984 1182196 ChemDiv1_026123 CN1C(=O)CC(Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D10 compound treatment 725653.0 245000.0 0.51 701281.0 244000.0 0.53 0.7308 0.9998 1982117 ChemDiv1_026124 OS(=O)(=O)c1cc2Cc3cc(cc([N+](=O)[O-])c3-c2c(c1)[N+](=O)[O-])S(=O)(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D11 compound treatment 776353.0 296000.0 0.61 713112.0 256000.0 0.55 0.8229 0.9988 1982118 ChemDiv1_026125 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4c(NC3c5ccccc5F)ccc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D12 compound treatment 883334.0 403000.0 0.83 836012.0 379000.0 0.82 1.1672 1.0 1264486 ChemDiv1_026126 CC(C)c1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccc(C)cc4)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D13 compound treatment 2129308.0 1650000.0 3.4 1490661.0 1030000.0 2.24 3.9878 0.9792 1424899 ChemDiv1_026127 O=C(N1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D14 compound treatment 712474.0 232000.0 0.48 696106.0 239000.0 0.52 0.7036 0.9993 1266884 ChemDiv1_026128 CC1(O)N(C2CC(C)(C)NC(C)(C)C2)C(=O)OC31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D15 compound treatment 775199.0 295000.0 0.61 759160.0 302000.0 0.65 0.8917 0.9994 1181858 ChemDiv1_026129 Clc1ncccc1C(=O)Nc2sc3CCCCCc3c2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D16 compound treatment 744387.0 264000.0 0.54 705686.0 248000.0 0.54 0.7649 1.0 1491095 ChemDiv1_026130 COC(c1oc2c(C)c3oc(=O)cc(C)c3cc2c1c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D17 compound treatment 769530.0 289000.0 0.6 755677.0 298000.0 0.65 0.8781 0.9992 1982119 ChemDiv1_026131 CC(C)(C)c1ccc(cc1)c2nnc3sc(=Cc4ccccc4Cl)c(=O)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D18 compound treatment 736580.0 256000.0 0.53 680579.0 223000.0 0.48 0.7151 0.999 1982120 ChemDiv1_026132 CC1(C)c2ccccc2N3CCC(=O)NC31/C=C/c4cccnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D19 compound treatment 785227.0 305000.0 0.63 725244.0 268000.0 0.58 0.8544 0.9992 1982121 ChemDiv1_026133 CC(=O)C1=NN(c2ccc(Br)cc2)C3(CCC(=NN3c4ccccc4)c5ccccc5)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D20 compound treatment 743441.0 263000.0 0.54 697041.0 240000.0 0.52 0.7503 0.9997 1982122 ChemDiv1_026134 CCOc1ccccc1NC(=O)c2c(NC(=O)c3cc(ccc3Cl)[N+](=O)[O-])sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D21 compound treatment 723520.0 243000.0 0.5 684616.0 227000.0 0.49 0.7022 0.9999 1700675 ChemDiv1_026135 CC(C)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D22 compound treatment 733496.0 253000.0 0.52 667687.0 210000.0 0.45 0.6908 0.9976 1212572 ChemDiv1_026136 Cn1c(=O)n(Cc2ccccc2F)c(=O)c3n(Cc4ccccc4)cnc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D23 mock treatment 715089.0 235000.0 0.48 674467.0 217000.0 0.47 0.6743 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 D24 mock treatment 242461.0 -238000.0 -0.49 214983.0 -243000.0 -0.52 -0.7188 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E01 compound treatment 654487.0 174000.0 0.36 587535.0 130000.0 0.28 0.4528 0.9927 1982123 ChemDiv1_026137 CCCCCCCCCCCCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(Cl)cc2)c3ccc(I)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E02 compound treatment 657600.0 177000.0 0.37 618043.0 161000.0 0.35 0.5041 0.9997 1320803 ChemDiv1_026138 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(o4)c5ccccc5F)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E03 compound treatment 728617.0 248000.0 0.51 692614.0 235000.0 0.51 0.7219 1.0 1512611 ChemDiv1_026139 CCOc1ccc(NC(=O)c2c(NC(=O)COc3ccccc3)sc4CCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E04 compound treatment 676490.0 196000.0 0.4 666525.0 209000.0 0.45 0.6059 0.9984 1982124 ChemDiv1_026140 COc1cccc2C3C(Cl)C(CC3C(Nc12)c4ccc(cc4)[N+](=O)[O-])Sc5ccccc5[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E05 compound treatment 902810.0 422000.0 0.87 929604.0 472000.0 1.02 1.3388 0.9969 1982125 ChemDiv1_026141 COc1ccc(cc1)N2C(N(N=C2C(=O)C)c3ccc(Cl)cc3)c4ccc(OCc5ccc(Cl)cc5)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E06 compound treatment 725418.0 245000.0 0.51 682041.0 225000.0 0.49 0.701 0.9998 1178463 ChemDiv1_026142 COc1ccc(C2N(Cc3ccccc3)C(=O)C(=C2C(=O)c4ccccc4)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E07 compound treatment 740572.0 260000.0 0.54 707082.0 250000.0 0.54 0.7615 1.0 1982126 ChemDiv1_026143 CCOC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccc(Cl)cc5)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E08 compound treatment 729305.0 249000.0 0.51 704902.0 247000.0 0.54 0.7417 0.9998 1982127 ChemDiv1_026144 Cc1cc(Cl)ccc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E09 compound treatment 742434.0 262000.0 0.54 726982.0 269000.0 0.58 0.7946 0.9993 1534064 ChemDiv1_026145 COc1cc2CC(C)(C)N=C(CC#N)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E10 compound treatment 744181.0 264000.0 0.54 626692.0 169000.0 0.37 0.6437 0.9814 1982128 ChemDiv1_026146 COc1ccc(cc1)C(=O)N2N=C3N(C2N4CCCCC4)S(=O)(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E11 compound treatment 750069.0 269000.0 0.56 667474.0 210000.0 0.45 0.7147 0.995 1491970 ChemDiv1_026147 Cc1ccc(cc1)N2CCN(C2c3ccc(OCC(=O)N)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E12 compound treatment 739759.0 259000.0 0.54 718735.0 261000.0 0.57 0.7781 0.9996 1607383 ChemDiv1_026148 COc1ccc(C=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E13 compound treatment 742555.0 262000.0 0.54 725937.0 268000.0 0.58 0.7932 0.9994 1982129 ChemDiv1_026149 Clc1ccc(C=c2sc3nnc(c4ccccc4Cl)n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E14 compound treatment 728843.0 248000.0 0.51 722534.0 265000.0 0.57 0.768 0.9984 1308809 ChemDiv1_026150 COC(=O)C1(OC)N(C(=O)C(=C1C(=O)c2ccc(Cl)cc2)OC(c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E15 compound treatment 783055.0 302000.0 0.62 769481.0 312000.0 0.68 0.919 0.9992 1696038 ChemDiv1_026151 CC1(C)CC2(CC(Oc3cc(O)c(Cl)cc32)c4ccccc4)NC(=S)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E16 compound treatment 896486.0 416000.0 0.86 909335.0 452000.0 0.98 1.2986 0.9979 1187230 ChemDiv1_026152 CC(=O)Nc1c2-c3ccccc3C(=O)c4cccc(n(C)c1=O)c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E17 compound treatment 753482.0 273000.0 0.56 758033.0 301000.0 0.65 0.8583 0.9974 1982130 ChemDiv1_026153 CCOC(=O)C(NC(=O)c1ccccc1Cl)(Nc2sc3CCCCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E18 compound treatment 732678.0 252000.0 0.52 684771.0 227000.0 0.49 0.7158 0.9996 1634605 ChemDiv1_026154 COC(=O)C1(O)N(C(=O)C(=C1C(=O)c2ccccc2)O)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E19 compound treatment 748503.0 268000.0 0.55 762351.0 305000.0 0.66 0.8576 0.9961 1591432 ChemDiv1_026155 C(#Cc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E20 compound treatment 731677.0 251000.0 0.52 719502.0 262000.0 0.57 0.7675 0.999 1782537 ChemDiv1_026156 Cn1c(=O)c([N+](=O)[O-])c(Cl)c2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E21 compound treatment 750617.0 270000.0 0.56 704105.0 247000.0 0.53 0.7716 0.9998 1982131 ChemDiv1_026157 Cc1ccnc2-c3ccc(cc3C(=O)c21)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E22 compound treatment 718110.0 238000.0 0.49 691766.0 234000.0 0.51 0.7052 0.9999 1982132 ChemDiv1_026158 OCCN1C(C(=C(O)C1=O)C(=O)c2ccc(Br)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E23 mock treatment 692619.0 212000.0 0.44 656375.0 199000.0 0.43 0.6139 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 E24 mock treatment 235445.0 -245000.0 -0.51 220177.0 -237000.0 -0.51 -0.721 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F01 compound treatment 621254.0 141000.0 0.29 595949.0 138000.0 0.3 0.4172 0.9999 1982133 ChemDiv1_026159 Clc1ccc(cc1)C(=O)CSc2sc(=S)sc2SCC(=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F02 compound treatment 685461.0 205000.0 0.42 642415.0 185000.0 0.4 0.582 0.9996 1982134 ChemDiv1_026160 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C(C)C)c3c(C)cc(C)cc23)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F03 compound treatment 1.6398449E7 1.59E7 32.86 1.0820223E7 1.04E7 22.43 39.0947 0.9827 1603666 ChemDiv1_026161 CCCCN1C(=O)C(=c2sc(=C3Sc4ccc(OC)cc4N3CC)c(=O)n2CC=C)SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F04 compound treatment 705067.0 224000.0 0.46 1421940.0 964000.0 2.09 1.8037 0.8435 1129635 ChemDiv1_026162 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccccc4O)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F05 compound treatment 2065285.0 1580000.0 3.27 2022702.0 1570000.0 3.39 4.7086 0.9998 1678516 ChemDiv1_026163 COc1cc(ccc1OCc2ccccc2F)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F06 compound treatment 730089.0 250000.0 0.52 661817.0 204000.0 0.44 0.6769 0.9971 1982135 ChemDiv1_026164 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccc(cc3)C(C)(C)C)c4ccc(OCC)cc24)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F07 compound treatment 755382.0 275000.0 0.57 726434.0 269000.0 0.58 0.8127 0.9999 1982136 ChemDiv1_026165 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4ccccc4N(C(=O)CC(C)C)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F08 compound treatment 759131.0 279000.0 0.57 690963.0 233000.0 0.51 0.7639 0.9979 1982137 ChemDiv1_026166 OCC1OC(C(O)C1O)n2ccc(=O)[nH]c2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F09 compound treatment 799083.0 318000.0 0.66 713749.0 256000.0 0.55 0.8571 0.9964 1201466 ChemDiv1_026167 C=CCN1C(=O)CC(Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F10 compound treatment 782578.0 302000.0 0.62 720168.0 263000.0 0.57 0.8428 0.9989 1176901 ChemDiv1_026168 CCOC(=O)c1nnn(c1CN2CCN(CC2)C(c3ccccc3)c4ccccc4)c5nonc5N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F11 compound treatment 805465.0 325000.0 0.67 768801.0 311000.0 0.67 0.9506 1.0 1982138 ChemDiv1_026169 c1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccc5c(c4)sc6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F12 compound treatment 823212.0 343000.0 0.71 711052.0 254000.0 0.55 0.8882 0.9921 1982139 ChemDiv1_026170 CC(C)c1ccc(/C=C/2\C(=O)N(C3=C2C(N(C3=O)c4ccc(C)cc4)c5ccccc5)c6ccc(C)cc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F13 compound treatment 737950.0 257000.0 0.53 720651.0 263000.0 0.57 0.7784 0.9994 1436542 ChemDiv1_026171 CCOc1ccc(NC(=O)c2c(NC(=O)C)sc3CCCc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F14 compound treatment 767291.0 287000.0 0.59 713402.0 256000.0 0.55 0.8101 0.9995 1982140 ChemDiv1_026172 CC1(O)N(CCCCCCN2C(=O)OC3(CCCCC3)C2(C)O)C(=O)OC41CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F15 compound treatment 791539.0 311000.0 0.64 746090.0 289000.0 0.62 0.8956 0.9999 1139335 ChemDiv1_026173 COc1cccc(c1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccc(O)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F16 compound treatment 769935.0 289000.0 0.6 735632.0 278000.0 0.6 0.848 1.0 1982141 ChemDiv1_026174 [O-][N+](=O)c1ccc(N2CCN(Cc3ccccc3)CC2)c(c1)C(=O)Nc4ccc(OC(F)(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F17 compound treatment 812223.0 332000.0 0.68 747303.0 290000.0 0.63 0.9276 0.999 1982142 ChemDiv1_026175 CCc1ccc(cc1)C2(SC3(SC(=NN3c4ccc(Cl)cc4)C(=O)C)c5ccccc52)c6ccc(CC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F18 compound treatment 736462.0 256000.0 0.53 671370.0 214000.0 0.46 0.7008 0.9978 1982143 ChemDiv1_026176 Cc1ccc2N3CCC(=O)NC3(/C=C/c4cccnc4)C(C)(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F19 compound treatment 773322.0 293000.0 0.6 737668.0 280000.0 0.61 0.8561 1.0 1982144 ChemDiv1_026177 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(Nc4ccccc4S3)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F20 compound treatment 755411.0 275000.0 0.57 704358.0 247000.0 0.53 0.779 0.9996 1546935 ChemDiv1_026178 CCC(C)(C)C1CCC2(CC1)NN(C(=S)N2)c3cccc(C)c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F21 compound treatment 733747.0 253000.0 0.52 720635.0 263000.0 0.57 0.7722 0.9991 1525290 ChemDiv1_026179 Cc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F22 compound treatment 1123321.0 643000.0 1.33 1069125.0 612000.0 1.32 1.8742 1.0 1982145 ChemDiv1_026180 CCOC(=O)C1CCN(CC1)c2ccc(cc2C(=O)Nc3ccc(OC(F)(F)F)cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F23 mock treatment 711350.0 231000.0 0.48 699158.0 242000.0 0.52 0.7067 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 F24 mock treatment 243277.0 -237000.0 -0.49 180594.0 -277000.0 -0.6 -0.7702 -0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G01 compound treatment 620770.0 140000.0 0.29 590237.0 133000.0 0.29 0.4078 1.0 1625119 ChemDiv1_026181 COc1cc(ccc1O)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G02 compound treatment 660811.0 180000.0 0.37 602655.0 145000.0 0.31 0.4852 0.9965 1982146 ChemDiv1_026182 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)c2nc(c([nH]2)c3ccccc3)c4ccc5c(c4)sc6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G03 compound treatment 703177.0 223000.0 0.46 646308.0 189000.0 0.41 0.6139 0.9983 1982147 ChemDiv1_026183 Cc1cc2CSC(SCc2cc1C)c3cc(Cl)cc(Cl)c3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G04 compound treatment 663852.0 183000.0 0.38 644978.0 187000.0 0.41 0.5544 0.9994 1982148 ChemDiv1_026184 ClCCC(=O)N1C(CC(=O)Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G05 compound treatment 727689.0 247000.0 0.51 679467.0 222000.0 0.48 0.7004 0.9996 1927437 ChemDiv1_026185 CCC1(CC)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G06 compound treatment 717586.0 237000.0 0.49 687174.0 230000.0 0.5 0.6974 1.0 1982149 ChemDiv1_026186 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N/Nc2ccccc2OC)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G07 compound treatment 729294.0 249000.0 0.51 678073.0 221000.0 0.48 0.7006 0.9993 1982150 ChemDiv1_026187 CC(=O)C1=NN(c2cccc(Cl)c2)C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G08 compound treatment 722448.0 242000.0 0.5 647957.0 190000.0 0.41 0.6445 0.9955 1783167 ChemDiv1_026188 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2cc(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G09 compound treatment 757546.0 277000.0 0.57 712843.0 255000.0 0.55 0.7951 0.9999 1661009 ChemDiv1_026189 CCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(c3ccc(C)cc3)C2(O)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G10 compound treatment 729509.0 249000.0 0.51 679204.0 222000.0 0.48 0.7026 0.9994 1982151 ChemDiv1_026190 COc1ccc2NC(C)(C)c3ssc(=Nc4cc(Cl)cc(Cl)c4)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G11 compound treatment 780805.0 300000.0 0.62 730260.0 273000.0 0.59 0.8557 0.9997 1982152 ChemDiv1_026191 CCCOc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G12 compound treatment 736957.0 256000.0 0.53 701047.0 244000.0 0.53 0.7469 1.0 1528622 ChemDiv1_026192 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccco4)c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G13 compound treatment 768110.0 288000.0 0.59 716159.0 259000.0 0.56 0.8156 0.9996 1982153 ChemDiv1_026193 Cc1ccc(cc1)c2nnc3sc(=Cc4ccc(cc4)[N+](=O)[O-])c(=O)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G14 compound treatment 736609.0 256000.0 0.53 705170.0 248000.0 0.54 0.7528 1.0 1363542 ChemDiv1_026194 COC(=O)C1(OC)N(C(=O)C(=C1C(=O)c2ccc(C)cc2)OC(c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G15 compound treatment 797227.0 317000.0 0.65 773651.0 316000.0 0.68 0.946 0.9997 1982154 ChemDiv1_026195 [O-][N+](=O)c1cc(ccc1Cl)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G16 compound treatment 733067.0 252000.0 0.52 701287.0 244000.0 0.53 0.7416 1.0 1982155 ChemDiv1_026196 CC(=O)C1=NN(c2ccc(C)cc2)C3(S1)SC(c4ccccc43)(c5ccc(Cl)cc5)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G17 compound treatment 820324.0 340000.0 0.7 816546.0 359000.0 0.78 1.0454 0.9987 1982156 ChemDiv1_026197 CC(C)(C)C(=O)[C@H]1[C@H](c2cccc(Cl)c2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G18 compound treatment 754219.0 274000.0 0.56 713269.0 256000.0 0.55 0.7909 0.9999 1982157 ChemDiv1_026198 [O-][N+](=O)c1cc2OCOc2cc1C=c3sc4nc5cc(Br)cnc5n4c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G19 compound treatment 777359.0 297000.0 0.61 735979.0 278000.0 0.6 0.8594 1.0 1982158 ChemDiv1_026199 CC(=O)Oc1ccc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G20 compound treatment 932180.0 452000.0 0.93 680604.0 223000.0 0.48 1.0006 0.9531 1982159 ChemDiv1_026200 [O-][N+](=O)c1c(N2CCOCC2)c3ccccc3n(c4ccccc4)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G21 compound treatment 745347.0 265000.0 0.55 690221.0 233000.0 0.5 0.7426 0.9992 1267208 ChemDiv1_026201 CCCS(=O)(=O)c1c(C(=O)c2ccccc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G22 compound treatment 704173.0 224000.0 0.46 693450.0 236000.0 0.51 0.6875 0.9987 1464759 ChemDiv1_026202 Cc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G23 mock treatment 697727.0 217000.0 0.45 654346.0 197000.0 0.43 0.6182 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 G24 mock treatment 214554.0 -266000.0 -0.55 191663.0 -266000.0 -0.58 -0.7952 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H01 compound treatment 622979.0 142000.0 0.29 585966.0 128000.0 0.28 0.4045 0.9996 1982160 ChemDiv1_026203 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc(Br)cc(Br)c4OCc5ccc(Cl)cc5Cl)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H02 compound treatment 670642.0 190000.0 0.39 593891.0 136000.0 0.3 0.4862 0.9902 1522402 ChemDiv1_026204 Cc1cc(=O)oc2c3c(Nc4ccc(Cl)c(Cl)c4)coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H03 compound treatment 781906.0 301000.0 0.62 720910.0 263000.0 0.57 0.843 0.9991 1782536 ChemDiv1_026205 Cc1cccc(Oc2c([N+](=O)[O-])c(=O)n(C)c3ccccc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H04 compound treatment 692450.0 212000.0 0.44 641898.0 184000.0 0.4 0.5915 0.999 1579111 ChemDiv1_026206 CC(=O)NCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H05 compound treatment 745296.0 265000.0 0.55 665513.0 208000.0 0.45 0.7047 0.9954 1581691 ChemDiv1_026207 COc1cc(cc(Br)c1OC(=O)C)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H06 compound treatment 707631.0 227000.0 0.47 655461.0 198000.0 0.43 0.6344 0.999 1982161 ChemDiv1_026208 CCOC(=O)C1=NN(C(N1C(C)(C)C)c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H07 compound treatment 731034.0 250000.0 0.52 691126.0 234000.0 0.51 0.7231 0.9999 1519669 ChemDiv1_026209 O=C(N1CCC(=O)Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H08 compound treatment 709322.0 229000.0 0.47 670544.0 213000.0 0.46 0.6599 0.9999 1982162 ChemDiv1_026210 CCN(CC)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H09 compound treatment 767187.0 287000.0 0.59 678226.0 221000.0 0.48 0.7561 0.9944 1982163 ChemDiv1_026211 CCc1ccc(cc1)n2nc(C)c(C(c3c(C)nn(c3O)c4ccc(CC)cc4)c5ccccc5O)c2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H10 compound treatment 714278.0 234000.0 0.48 687160.0 230000.0 0.5 0.6926 0.9999 1461661 ChemDiv1_026212 CC(=O)Nc1cc2c(C)cc(=O)oc2c3c(Nc4ccccc4)coc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H11 compound treatment 781976.0 301000.0 0.62 723548.0 266000.0 0.58 0.8471 0.9993 1982164 ChemDiv1_026213 Fc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc5c(c4)sc6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H12 compound treatment 2768722.0 2290000.0 4.72 3839524.0 3380000.0 7.32 8.516 0.9775 1982165 ChemDiv1_026214 c1ccc(cc1)c2nc3nc(c4ccccc4)c(nn3c2c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H13 compound treatment 757730.0 277000.0 0.57 719910.0 262000.0 0.57 0.8061 1.0 1427814 ChemDiv1_026215 Cc1cccc(c1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H14 compound treatment 763026.0 282000.0 0.58 645284.0 188000.0 0.41 0.6997 0.9844 1421795 ChemDiv1_026216 COc1cc(cc(OC)c1O)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H15 compound treatment 768556.0 288000.0 0.59 730177.0 273000.0 0.59 0.8377 1.0 1227677 ChemDiv1_026217 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C)C2c3ccc(OC)cc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H16 compound treatment 740009.0 259000.0 0.54 678069.0 221000.0 0.48 0.7162 0.9984 1982166 ChemDiv1_026218 CCN1CCN(CC1)c2ccc(cc2C(=O)Nc3ccc(OC(F)(F)F)cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H17 compound treatment 760813.0 280000.0 0.58 737769.0 280000.0 0.61 0.838 0.9997 1982167 ChemDiv1_026219 CCc1ccc(cc1)C2(SC3(SC(=NN3c4cccc(Cl)c4C)C(=O)C)c5ccccc52)c6ccc(CC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H18 compound treatment 727694.0 247000.0 0.51 666971.0 209000.0 0.45 0.6813 0.9983 1982168 ChemDiv1_026220 CC(C)(C)C1CCC2(CC1)NN(C(=S)N2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H19 compound treatment 752284.0 272000.0 0.56 678851.0 221000.0 0.48 0.7354 0.9969 1651735 ChemDiv1_026221 CCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(C)c(Cl)c5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H20 compound treatment 727415.0 247000.0 0.51 636240.0 179000.0 0.39 0.6338 0.9908 1912937 ChemDiv1_026222 [O-][N+](=O)c1ccccc1C2=Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H21 compound treatment 733808.0 253000.0 0.52 707704.0 250000.0 0.54 0.7525 0.9998 1438746 ChemDiv1_026223 Cc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H22 compound treatment 725768.0 245000.0 0.51 693734.0 236000.0 0.51 0.7194 1.0 1598995 ChemDiv1_026224 OC(=O)CCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H23 mock treatment 702000.0 221000.0 0.46 669206.0 212000.0 0.46 0.6472 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 H24 mock treatment 239958.0 -241000.0 -0.5 219664.0 -238000.0 -0.51 -0.7152 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I01 compound treatment 620890.0 140000.0 0.29 580492.0 123000.0 0.27 0.393 0.9991 1336867 ChemDiv1_026225 C1CCC(C1)Sc2nnc(c3ccccc3)c(n2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I02 compound treatment 700156.0 220000.0 0.45 646538.0 189000.0 0.41 0.6098 0.9987 1364838 ChemDiv1_026226 CC1(C)CC2(CC(Oc3cc(O)ccc32)c4ccccc4Cl)NC(=S)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I03 compound treatment 687850.0 207000.0 0.43 645655.0 188000.0 0.41 0.5905 0.9997 1456243 ChemDiv1_026227 Brc1cc(Br)c2OC3(CCCCC3=Cc2c1)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I04 compound treatment 695755.0 215000.0 0.44 648053.0 191000.0 0.41 0.6057 0.9993 1544276 ChemDiv1_026228 Cc1cccc2C(=C3C(=O)CCCC3=O)NC(C)(C)Cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I05 compound treatment 731616.0 251000.0 0.52 682080.0 225000.0 0.49 0.7101 0.9995 1135069 ChemDiv1_026229 CC1CCC2(CC1)NN(C(=S)N2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I06 compound treatment 704136.0 224000.0 0.46 656844.0 199000.0 0.43 0.6314 0.9994 1783170 ChemDiv1_026230 COc1ccc(OC)c(c1)S(=O)(=O)n2c(C)ncc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I07 compound treatment 717640.0 237000.0 0.49 693750.0 236000.0 0.51 0.7076 0.9998 1982169 ChemDiv1_026231 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I08 compound treatment 711928.0 231000.0 0.48 676538.0 219000.0 0.47 0.6729 1.0 1982170 ChemDiv1_026232 [O-][N+](=O)c1ccccc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I09 compound treatment 750541.0 270000.0 0.56 709040.0 252000.0 0.54 0.779 0.9999 1982171 ChemDiv1_026233 CN1CCC2C(C1)c3cc(C)ccc3N2S(=O)(=O)c4c(C)[nH]c(=O)[nH]c4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I10 compound treatment 725435.0 245000.0 0.51 655559.0 198000.0 0.43 0.6605 0.9966 1982172 ChemDiv1_026234 COc1ccc(N=c2ssc3c2-c4cc(OC)ccc4NC3(C)C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I11 compound treatment 743710.0 263000.0 0.54 631156.0 174000.0 0.38 0.6498 0.9838 1982173 ChemDiv1_026235 COC(=O)C1=NNC2(C)C1C(=O)N(C2=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I12 compound treatment 737279.0 257000.0 0.53 662307.0 205000.0 0.44 0.6881 0.9961 1982174 ChemDiv1_026236 CN1C(=O)N(C)C2(N=c3sc(=Cc4cc5OCOc5cc4Br)c(=O)n3NC12c6ccccc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I13 compound treatment 1700259.0 1220000.0 2.52 682398.0 225000.0 0.49 2.1245 0.8285 1982175 ChemDiv1_026237 Cc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)CN3C(=O)c4ccccc4C3=O)c5ccc(cc52)C(c6ccccc6)(c7ccccc7)c8ccccc8 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I14 compound treatment 731866.0 251000.0 0.52 711245.0 254000.0 0.55 0.7551 0.9996 1982176 ChemDiv1_026238 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccccc4Br)c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I15 compound treatment 810138.0 330000.0 0.68 758767.0 301000.0 0.65 0.9421 0.9998 1782679 ChemDiv1_026239 CCOC(=O)N1CC=C2C(C1)C(c3cccs3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I16 compound treatment 727853.0 247000.0 0.51 688817.0 231000.0 0.5 0.7149 1.0 1982177 ChemDiv1_026240 CC(=O)C1=NN(c2ccc(cc2)[N+](=O)[O-])C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I17 compound treatment 1.3679223E7 1.32E7 27.25 1.3604019E7 1.31E7 28.45 39.386 0.9998 1353266 ChemDiv1_026241 Cc1ccc2C(=O)c3ccccc3-c4c(N)c(=O)[nH]c1c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I18 compound treatment 754436.0 274000.0 0.57 685301.0 228000.0 0.49 0.7484 0.9977 1165778 ChemDiv1_026242 Cc1ccc(cc1C)c2nc([nH]c2c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I19 compound treatment 1003356.0 523000.0 1.08 956374.0 499000.0 1.08 1.5266 1.0 1982178 ChemDiv1_026243 Fc1cccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I20 compound treatment 741145.0 261000.0 0.54 698732.0 241000.0 0.52 0.7495 0.9999 1924071 ChemDiv1_026244 [O-][N+](=O)c1c(NC2CCCCC2)c3ccccc3n(c4ccccc4)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I21 compound treatment 1697422.0 1220000.0 2.51 2059863.0 1600000.0 3.47 4.2285 0.9875 1436725 ChemDiv1_026245 CN1CC=C2C(C1)C(c3cccc(O)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I22 compound treatment 689679.0 209000.0 0.43 676548.0 219000.0 0.47 0.6404 0.9989 1982179 ChemDiv1_026246 OC1=C(C(N(C1=O)c2ccc(F)cc2)c3ccc(Br)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I23 mock treatment 710591.0 230000.0 0.47 635323.0 178000.0 0.38 0.6079 0.9946 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 I24 mock treatment 217905.0 -263000.0 -0.54 256514.0 -201000.0 -0.44 -0.691 -0.994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J01 compound treatment 630920.0 150000.0 0.31 586949.0 129000.0 0.28 0.4175 0.9987 1779034 ChemDiv1_026247 COc1ccc(cc1[N+](=O)[O-])c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J02 compound treatment 679635.0 199000.0 0.41 638251.0 181000.0 0.39 0.5672 0.9997 1982180 ChemDiv1_026248 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cc(Cl)cc(C(=O)c5ccccc5)c4NC3c6ccccc6F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J03 compound treatment 737520.0 257000.0 0.53 687336.0 230000.0 0.5 0.7268 0.9995 1982181 ChemDiv1_026249 Cn1c(=O)c([N+](=O)[O-])c(Sc2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J04 compound treatment 700747.0 220000.0 0.45 668459.0 211000.0 0.46 0.6442 1.0 1252957 ChemDiv1_026250 COc1ccc(cc1)C2N(CCNC(=O)C)C(=O)C(=C2C(=O)c3ccccc3)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J05 compound treatment 945987.0 465000.0 0.96 673272.0 216000.0 0.47 1.0096 0.9451 1982182 ChemDiv1_026251 CCc1c(oc2ccc3c(C)cc(=O)oc3c12)/C(=N/O)/C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J06 compound treatment 717565.0 237000.0 0.49 678145.0 221000.0 0.48 0.6836 0.9999 1982183 ChemDiv1_026252 CC(=O)Oc1cc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)ccc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J07 compound treatment 738559.0 258000.0 0.53 729393.0 272000.0 0.59 0.7927 0.9988 1709338 ChemDiv1_026253 CC(=O)N1C(CC(=O)N(C(=O)C)c2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J08 compound treatment 752173.0 272000.0 0.56 687988.0 230000.0 0.5 0.7492 0.9983 1982184 ChemDiv1_026254 CCOC(=O)C1=NN(c2cccc(Cl)c2)C3(Nc4ccccc4S3)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J09 compound treatment 749614.0 269000.0 0.56 690656.0 233000.0 0.5 0.7495 0.9989 1982185 ChemDiv1_026255 N#Cc1ccc(CSc2nnc(c3ccco3)n2c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J10 compound treatment 723678.0 243000.0 0.5 658587.0 201000.0 0.44 0.6626 0.9975 1982186 ChemDiv1_026256 CCOc1ccccc1NC(=O)c2cc(ccc2N3CCCCCC3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J11 compound treatment 762171.0 282000.0 0.58 732644.0 275000.0 0.6 0.8321 0.9999 1588794 ChemDiv1_026257 CC(C)C1Nc2c(cc(Cl)cc2C3C=CCC31)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J12 compound treatment 904511.0 424000.0 0.88 969751.0 512000.0 1.11 1.4028 0.9931 1982187 ChemDiv1_026258 c1ccc(cc1)c2c(nc3nc(c4ccccc4)c(nn23)c5ccccc5)c6ccc(cc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J13 compound treatment 774744.0 294000.0 0.61 698262.0 241000.0 0.52 0.7978 0.9971 1417289 ChemDiv1_026259 Cc1cccc(c1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J14 compound treatment 722897.0 242000.0 0.5 699731.0 242000.0 0.52 0.7244 0.9997 1154382 ChemDiv1_026260 COc1cc(cc(OC)c1OC)C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J15 compound treatment 770224.0 290000.0 0.6 704851.0 247000.0 0.54 0.8013 0.9985 1982188 ChemDiv1_026261 COc1ccc(C=c2sc3nnc(c4ccc(C)cc4)n3c2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J16 compound treatment 741903.0 261000.0 0.54 715623.0 258000.0 0.56 0.7765 0.9998 1982189 ChemDiv1_026262 Cc1ccc(cc1)N2C(C/3=C(N(C(=O)\C3=C/c4cccc(c4)[N+](=O)[O-])c5ccc(C)cc5)C2=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J17 compound treatment 773912.0 293000.0 0.61 755181.0 298000.0 0.64 0.8837 0.9995 1982190 ChemDiv1_026263 OC1=C(C(N(C1=O)c2nccs2)c3ccc(F)cc3)C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J18 compound treatment 726112.0 246000.0 0.51 702726.0 245000.0 0.53 0.7337 0.9997 1274173 ChemDiv1_026264 Cc1cccc2C(=C3C(=O)CC(C)(C)CC3=O)NC(C)(C)Cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J19 compound treatment 796129.0 316000.0 0.65 733786.0 276000.0 0.6 0.8834 0.9991 1589101 ChemDiv1_026265 Clc1ccccc1c2nn(CN3CCC(Cc4ccccc4)CC3)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J20 compound treatment 728958.0 248000.0 0.51 712964.0 255000.0 0.55 0.7535 0.9993 1912939 ChemDiv1_026266 [O-][N+](=O)c1cccc(c1)C2=Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J21 compound treatment 762098.0 282000.0 0.58 723434.0 266000.0 0.58 0.8179 1.0 1033403 ChemDiv1_026267 COC1OC(COC(c2ccccc2)(c3ccccc3)c4ccccc4)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J22 compound treatment 728540.0 248000.0 0.51 680531.0 223000.0 0.48 0.7033 0.9996 1982191 ChemDiv1_026268 COc1ccccc1/C=C/2\C(=O)N(C3=C2C(N(C3=O)c4ccc(C)cc4)c5ccccc5)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J23 mock treatment 745888.0 265000.0 0.55 685627.0 228000.0 0.49 0.7364 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 J24 mock treatment 190259.0 -290000.0 -0.6 205736.0 -252000.0 -0.54 -0.8091 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K01 compound treatment 970453.0 490000.0 1.01 902168.0 445000.0 0.96 1.3956 0.9997 1982192 ChemDiv1_026269 COc1ccc2S/C(=C/3\SC(=S)N(CC(=O)O)C3=O)/N(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K02 compound treatment 641288.0 161000.0 0.33 621170.0 164000.0 0.35 0.4851 0.9995 1300529 ChemDiv1_026270 CC1(C)CC2(CC(Oc3cc(O)c(Cl)cc32)c4ccccc4Cl)NC(=S)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K03 compound treatment 724134.0 244000.0 0.5 637228.0 180000.0 0.39 0.6306 0.992 1256336 ChemDiv1_026271 CCc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K04 compound treatment 692723.0 212000.0 0.44 662275.0 205000.0 0.44 0.623 1.0 1945666 ChemDiv1_026272 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccc4OCOc4c3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K05 compound treatment 709072.0 228000.0 0.47 668274.0 211000.0 0.46 0.6561 0.9999 1982193 ChemDiv1_026273 CCOC(=O)C1=NN(c2ccc(Br)cc2)C3(S1)SC(c4ccccc43)(c5ccc(Cl)cc5)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K06 compound treatment 700218.0 220000.0 0.45 672118.0 215000.0 0.46 0.649 0.9999 1783169 ChemDiv1_026274 COc1ccc(cc1OC)S(=O)(=O)n2c(C)ncc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K07 compound treatment 718570.0 238000.0 0.49 676832.0 219000.0 0.47 0.683 0.9999 1982194 ChemDiv1_026275 CCOC(=O)C1=NN(c2ccccc2)C3(S1)SC(c4ccccc43)(c5ccccc5C)c6ccccc6C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K08 compound treatment 710460.0 230000.0 0.47 657883.0 200000.0 0.43 0.6422 0.999 1783168 ChemDiv1_026276 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2ccc(C)cc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K09 compound treatment 740588.0 260000.0 0.54 670516.0 213000.0 0.46 0.7055 0.9971 1517526 ChemDiv1_026277 Cc1cc(C)c2NC(C)(C)c3sn(c4ccc(Cl)cc4)c(=S)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K10 compound treatment 738310.0 258000.0 0.53 651901.0 194000.0 0.42 0.6737 0.9932 1722106 ChemDiv1_026278 COc1ccc(N=c2ssc3c2-c4ccc(C)cc4NC3(C)C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K11 compound treatment 757843.0 277000.0 0.57 709426.0 252000.0 0.55 0.7903 0.9997 1506371 ChemDiv1_026279 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(ccc1c24)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K12 compound treatment 678307.0 198000.0 0.41 617853.0 160000.0 0.35 0.534 0.9967 1560604 ChemDiv1_026280 CC1=C(C(CC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OC3CCCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K13 compound treatment 762393.0 282000.0 0.58 668052.0 211000.0 0.46 0.7336 0.9927 1982195 ChemDiv1_026281 Fc1ccc(cc1)C2OC3(C(c4ccc(Cl)cc4)C25C(=O)c6ccccc6C5=O)C(=O)c7ccccc7C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K14 compound treatment 2133834.0 1650000.0 3.41 1991306.0 1530000.0 3.32 4.7606 0.9999 1982196 ChemDiv1_026282 CN(C)c1ccc(C=c2sc3=NN=C(C(c4ccccc4)n3c2=O)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K15 compound treatment 720592.0 240000.0 0.5 682837.0 225000.0 0.49 0.6952 1.0 1982197 ChemDiv1_026283 Clc1ccc(cc1)c2[nH]c(nc2c3ccccc3)c4cccc(C#Cc5ccccc5)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K16 compound treatment 714235.0 234000.0 0.48 680305.0 223000.0 0.48 0.682 1.0 1328131 ChemDiv1_026284 O=C1Nc2ccccc2NC(=O)C3C4c5ccccc5C(C31)c6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K17 compound treatment 890859.0 410000.0 0.85 814651.0 357000.0 0.77 1.1455 0.999 1196399 ChemDiv1_026285 CC(=O)Nc1ccc2n(C)c(=O)cc3-c4ccccc4C(=O)c1c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K18 compound treatment 708661.0 228000.0 0.47 669646.0 212000.0 0.46 0.6576 0.9999 1982198 ChemDiv1_026286 CCOc1ccc2N(C(=O)COc3ccc(F)cc3)C(C)(C)C(=S)C(=C4SC(=C(S4)C(=O)OC)C(=O)OC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K19 compound treatment 755275.0 275000.0 0.57 685408.0 228000.0 0.49 0.7498 0.9976 1226215 ChemDiv1_026287 CC1=C(C#Cc2ccccc2)c3ccccc3OC1(N4CCCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K20 compound treatment 971079.0 490000.0 1.01 843008.0 386000.0 0.83 1.306 0.9954 1912601 ChemDiv1_026288 CCC/C=C/1\CC(c2ccccc2)C(C#N)(C#N)C(=C1C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K21 compound treatment 761431.0 281000.0 0.58 678493.0 221000.0 0.48 0.7482 0.9954 1982199 ChemDiv1_026289 CC(=O)c1c(C)cc(C)c(CSc2nnc(c3ccco3)n2c4ccccc4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K22 compound treatment 718816.0 238000.0 0.49 674939.0 217000.0 0.47 0.6805 0.9998 1124110 ChemDiv1_026290 OC1=C(C(N(C1=O)c2ccc(F)cc2)c3ccc(F)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K23 mock treatment 718725.0 238000.0 0.49 657833.0 200000.0 0.43 0.6542 0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 K24 mock treatment 243539.0 -237000.0 -0.49 208511.0 -249000.0 -0.54 -0.7271 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L01 compound treatment 633871.0 153000.0 0.32 596678.0 139000.0 0.3 0.4367 0.9997 1982200 ChemDiv1_026291 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccc(cc3)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L02 compound treatment 684261.0 204000.0 0.42 653362.0 196000.0 0.42 0.597 1.0 1701560 ChemDiv1_026292 COc1cc(SC)ccc1C(=O)Nc2ccc3CCc4ccccc4N(C(=O)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L03 compound treatment 790754.0 310000.0 0.64 761413.0 304000.0 0.66 0.9179 0.9999 1982201 ChemDiv1_026293 Cn1c(=O)c([N+](=O)[O-])c(N2CCCC2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L04 compound treatment 672868.0 192000.0 0.4 668644.0 211000.0 0.46 0.6038 0.9975 1982202 ChemDiv1_026294 CC1(CC1(Cl)Cl)C(=O)Nc2ccc3OC4(CCCCC4)Oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L05 compound treatment 700711.0 220000.0 0.45 693949.0 236000.0 0.51 0.6832 0.9982 1982203 ChemDiv1_026295 COc1ccc(Br)cc1/C=C/2\CC(C/C(=C\c3cc(Br)ccc3OC)/C2=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L06 compound treatment 702629.0 222000.0 0.46 658372.0 201000.0 0.43 0.6315 0.9997 1450205 ChemDiv1_026296 CC1CC(C)(C)NC(=S)N1c2cccc(O)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L07 compound treatment 720248.0 240000.0 0.49 697339.0 240000.0 0.52 0.7169 0.9997 1276558 ChemDiv1_026297 CCC(=O)N1CC(C)C(=O)N(Cc2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L08 compound treatment 720539.0 240000.0 0.5 667280.0 210000.0 0.45 0.6713 0.9991 1186251 ChemDiv1_026298 CCN1C2NC(=O)NC2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L09 compound treatment 743217.0 263000.0 0.54 687478.0 230000.0 0.5 0.7353 0.9991 1347026 ChemDiv1_026299 Cc1ccc(Nc2coc3ccc4c(C)cc(=O)oc4c23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L10 compound treatment 722654.0 242000.0 0.5 681107.0 224000.0 0.48 0.6956 0.9999 1982204 ChemDiv1_026300 CCN1C(NNC(=S)N)C(NNC(=S)N)N(CC)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L11 compound treatment 719502.0 239000.0 0.49 703187.0 246000.0 0.53 0.7247 0.9993 1982205 ChemDiv1_026301 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cc(Cl)cc(C(=O)c5ccccc5)c4NC3c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L12 compound treatment 751979.0 271000.0 0.56 706606.0 249000.0 0.54 0.7774 0.9998 1982206 ChemDiv1_026302 Cc1nc2nc(cn2nc1C)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L13 compound treatment 867484.0 387000.0 0.8 647975.0 190000.0 0.41 0.8563 0.9527 1982207 ChemDiv1_026303 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccc(OC)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L14 compound treatment 694479.0 214000.0 0.44 670135.0 213000.0 0.46 0.6376 0.9998 1537991 ChemDiv1_026304 Fc1ccccc1C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L15 compound treatment 750856.0 270000.0 0.56 714077.0 257000.0 0.56 0.7872 1.0 1470836 ChemDiv1_026305 COc1ccc(cc1OC)C2SCCN2S(=O)(=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L16 compound treatment 733964.0 253000.0 0.52 695710.0 238000.0 0.52 0.7344 1.0 1485204 ChemDiv1_026306 CC(=O)Nc1cc2c(C)cc(=O)oc2c3c(Nc4cccc(C)c4)coc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L17 compound treatment 750851.0 270000.0 0.56 718575.0 261000.0 0.57 0.7941 1.0 1982208 ChemDiv1_026307 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3ccc(F)c(F)c3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L18 compound treatment 717672.0 237000.0 0.49 673272.0 216000.0 0.47 0.6763 0.9997 1156642 ChemDiv1_026308 CC(=O)Nc1cc2c(C)cc(=O)oc2c3c(Nc4ccc(Cl)cc4)coc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L19 compound treatment 748458.0 268000.0 0.55 714538.0 257000.0 0.56 0.7844 1.0 1395333 ChemDiv1_026309 CC1CCCN(Cn2nc(c3ccccc3Cl)n(c4ccccc4)c2=S)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L20 compound treatment 723119.0 243000.0 0.5 655403.0 198000.0 0.43 0.6569 0.997 1982209 ChemDiv1_026310 CCC(C)(C)C1CCC2(CC1)NN(C(=S)N2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L21 compound treatment 770994.0 290000.0 0.6 733056.0 276000.0 0.6 0.8456 1.0 1403353 ChemDiv1_026311 CCc1ccccc1Nc2coc3ccc4c(C)cc(=O)oc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L22 compound treatment 763370.0 283000.0 0.58 725457.0 268000.0 0.58 0.8229 1.0 1982210 ChemDiv1_026312 COc1cc2CC(C)(C)N=C(NC(CCSC)C(=O)O)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L23 mock treatment 735396.0 255000.0 0.53 679635.0 222000.0 0.48 0.7119 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 L24 mock treatment 222554.0 -258000.0 -0.53 255110.0 -202000.0 -0.44 -0.6864 -0.9953 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M01 compound treatment 654456.0 174000.0 0.36 580625.0 123000.0 0.27 0.4422 0.9893 1982211 ChemDiv1_026313 Clc1ccc(cc1)c2csc(n2)/C(=C/C3CCCCC3)/C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M02 compound treatment 666506.0 186000.0 0.38 611991.0 154000.0 0.33 0.5078 0.9976 1982212 ChemDiv1_026314 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccccc2Cl)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M03 compound treatment 721411.0 241000.0 0.5 642026.0 185000.0 0.4 0.6339 0.9941 1982213 ChemDiv1_026315 Cc1cc(=O)oc2c3C(=O)/C(=C/c4cccc(c4)[N+](=O)[O-])/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M04 compound treatment 684076.0 203000.0 0.42 640335.0 183000.0 0.4 0.5768 0.9996 1982214 ChemDiv1_026316 CCSC1=C(C#N)[C@@H](C(=C(C)N1)C(=O)C)c2ccccc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M05 compound treatment 719078.0 238000.0 0.49 604339.0 147000.0 0.32 0.5728 0.9776 1982215 ChemDiv1_026317 CC(=O)C1=NN(c2ccccc2)C3(S1)SC(c4ccccc43)(c5ccc(Br)cc5)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M06 compound treatment 676230.0 196000.0 0.4 649777.0 192000.0 0.42 0.5798 0.9999 1982216 ChemDiv1_026318 Clc1ccc(c(Cl)c1Cl)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M07 compound treatment 698818.0 218000.0 0.45 655368.0 198000.0 0.43 0.6214 0.9997 1982217 ChemDiv1_026319 CC(=O)C1=NN(C(N1C(C)(C)C)c2ccccc2OCc3c(Cl)cccc3Cl)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M08 compound treatment 684775.0 204000.0 0.42 653172.0 196000.0 0.42 0.5975 1.0 1982218 ChemDiv1_026320 Clc1ccc2n(nnc2c1)S(=O)(=O)c3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M09 compound treatment 742092.0 262000.0 0.54 691557.0 234000.0 0.51 0.7399 0.9995 1982219 ChemDiv1_026321 COc1ccc(/C=C/2\C(=O)N(C3=C2C(N(C3=O)c4ccccc4)c5ccc(Br)cc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M10 compound treatment 705815.0 225000.0 0.46 651224.0 194000.0 0.42 0.6252 0.9987 1982220 ChemDiv1_026322 CC1(C)Nc2ccccc2-c3c1ssc3=Nc4cc(Cl)cc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M11 compound treatment 707735.0 227000.0 0.47 674962.0 217000.0 0.47 0.6644 1.0 1721495 ChemDiv1_026323 CC1CN(CC(C)O1)C2(CCC(CC2)C(C)(C)C)n3nnc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M12 compound treatment 687449.0 207000.0 0.43 637589.0 180000.0 0.39 0.5776 0.999 1982221 ChemDiv1_026324 CCOC(=O)C1=C(S/C(=C\2/C(=S)C(C)(C)N(C)c3ccc(C)cc23)/S1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M13 compound treatment 731450.0 251000.0 0.52 663204.0 206000.0 0.45 0.681 0.9972 1982222 ChemDiv1_026325 [O-][N+](=O)CC(c1ccccc1)P(=O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M14 compound treatment 700614.0 220000.0 0.45 684518.0 227000.0 0.49 0.6686 0.9992 1982223 ChemDiv1_026326 COc1ccc(cc1)c2nc(c([nH]2)c3ccc4c(c3)sc5cc(ccc54)c6nc([nH]c6c7ccccc7)c8ccc(OC)cc8)c9ccccc9 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M15 compound treatment 741145.0 261000.0 0.54 688321.0 231000.0 0.5 0.7336 0.9993 1737049 ChemDiv1_026327 COc1cc(ccc1OCc2ccccc2)C3N(Cc4ccccc4)CCN3Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M16 compound treatment 707347.0 227000.0 0.47 664171.0 207000.0 0.45 0.6473 0.9997 1507453 ChemDiv1_026328 CC1(O)N(CCCC(=O)O)C(=O)OC21CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M17 compound treatment 761196.0 281000.0 0.58 693719.0 236000.0 0.51 0.7711 0.9981 1185840 ChemDiv1_026329 Brc1ccc2n(C3CCCCC3)c(=O)cc4-c5ccccc5C(=O)c1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M18 compound treatment 723228.0 243000.0 0.5 681763.0 224000.0 0.49 0.6974 0.9999 1982224 ChemDiv1_026330 CCOc1cccc2C3=C(SC(=C(C(=O)OC)C43SC(=C(S4)C(=O)OC)C(=O)OC)C(=O)OC)C(C)(C)N(C(=O)Cc5ccc(F)cc5)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M19 compound treatment 751962.0 271000.0 0.56 696051.0 239000.0 0.52 0.7612 0.9992 1255720 ChemDiv1_026331 CC1=C(C#Cc2ccccc2)c3ccccc3OC1(NC4CCCCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M20 compound treatment 748963.0 268000.0 0.55 686632.0 229000.0 0.5 0.7424 0.9985 1130774 ChemDiv1_026332 O=C1CCCc2c1sc3nc4CCCCCn4c(=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M21 compound treatment 754620.0 274000.0 0.57 704938.0 247000.0 0.54 0.7787 0.9996 1982225 ChemDiv1_026333 CC(C)c1ccc(cc1)C2C=C(Nc3cccc(Cl)c3)C(=O)N2c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M22 compound treatment 724971.0 244000.0 0.5 675241.0 218000.0 0.47 0.69 0.9994 1982226 ChemDiv1_026334 CC1(C)OC2OC(C3OC(C)(C)OC3C2O1)C(=O)NC(CCC(=O)O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M23 mock treatment 717150.0 237000.0 0.49 670032.0 213000.0 0.46 0.6706 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 M24 mock treatment 382205.0 -98400.0 -0.2 375398.0 -82100.0 -0.18 -0.2693 -0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N01 compound treatment 655145.0 175000.0 0.36 598648.0 141000.0 0.31 0.4708 0.9966 1278353 ChemDiv1_026335 COc1cc(cc(OC)c1OC)C(=O)N2c3ccc(C)cc3-c4c(ssc4=S)C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N02 compound treatment 745981.0 265000.0 0.55 714420.0 257000.0 0.56 0.7806 1.0 1982227 ChemDiv1_026336 CCCCCCCc1n2C(C)C(=C(C)c2cc3nc(C(=O)OCC)c(C)c13)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N03 compound treatment 738135.0 258000.0 0.53 711005.0 253000.0 0.55 0.7639 0.9999 1620124 ChemDiv1_026337 OC(CN1CCN(CC1)c2ccccn2)Cn3c4ccc(Cl)cc4c5cc(Cl)ccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N04 compound treatment 655328.0 175000.0 0.36 644233.0 187000.0 0.4 0.5408 0.9984 1982228 ChemDiv1_026338 CCC(C)(C)C1C/C(=C\c2cc(OC)c(OC)c(OC)c2)/C(=O)\C(=C\c3cc(OC)c(OC)c(OC)c3)\C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N05 compound treatment 698606.0 218000.0 0.45 692938.0 235000.0 0.51 0.6786 0.9981 1982229 ChemDiv1_026339 CC(C)(C)c1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4c2ccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N06 compound treatment 671610.0 191000.0 0.39 678073.0 221000.0 0.48 0.6164 0.9955 1982230 ChemDiv1_026340 CN1C2NNC(=O)NC2N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N07 compound treatment 705887.0 225000.0 0.47 681959.0 224000.0 0.49 0.6724 0.9998 1407135 ChemDiv1_026341 O=CN1CCC(=O)N(Cc2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N08 compound treatment 747633.0 267000.0 0.55 688032.0 231000.0 0.5 0.7426 0.9988 1982231 ChemDiv1_026342 O=C/1N=C(S\C1=C/c2ccccc2)N3CCN(CC3)C(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N09 compound treatment 750412.0 270000.0 0.56 719797.0 262000.0 0.57 0.7953 1.0 1982232 ChemDiv1_026343 Fc1ccc(cc1)c2nc(c([nH]2)c3ccc4c(c3)sc5ccccc54)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N10 compound treatment 708016.0 227000.0 0.47 678493.0 221000.0 0.48 0.6702 1.0 1982233 ChemDiv1_026344 COc1ccc(cc1)C2C=C(Nc3ccc(C)cc3)C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N11 compound treatment 718142.0 238000.0 0.49 696277.0 239000.0 0.52 0.7122 0.9997 1706978 ChemDiv1_026345 CCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)c(c5)C(=O)OC)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N12 compound treatment 758814.0 278000.0 0.57 727031.0 270000.0 0.58 0.8186 1.0 1665926 ChemDiv1_026346 Cc1nc2nc(c(c3ccccc3)n2nc1C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N13 compound treatment 684829.0 204000.0 0.42 639762.0 182000.0 0.39 0.5771 0.9994 1982234 ChemDiv1_026347 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccc(C)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N14 compound treatment 701572.0 221000.0 0.46 669327.0 212000.0 0.46 0.6468 1.0 1130503 ChemDiv1_026348 Clc1cccc(c1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N15 compound treatment 726981.0 246000.0 0.51 685583.0 228000.0 0.49 0.7087 0.9999 1190976 ChemDiv1_026349 COc1ccc(OC)c(c1)C2=NCC(=O)Nc3c2oc4ccc(Br)cc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N16 compound treatment 701847.0 221000.0 0.46 695594.0 238000.0 0.52 0.6874 0.9982 1982235 ChemDiv1_026350 Brc1ccc(C=c2sc3=NN=C(C(c4ccccc4)n3c2=O)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N17 compound treatment 728920.0 248000.0 0.51 711718.0 254000.0 0.55 0.7515 0.9994 1945359 ChemDiv1_026351 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3ccc(F)cc3F)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N18 compound treatment 702164.0 222000.0 0.46 678464.0 221000.0 0.48 0.6616 0.9998 1345335 ChemDiv1_026352 Cc1ccc(cc1)c2n[nH]c3C(=O)N(C(c23)c4ccccc4Cl)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N19 compound treatment 715713.0 235000.0 0.49 682519.0 225000.0 0.49 0.6876 1.0 1377401 ChemDiv1_026353 Oc1ccc(cc1O)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N20 compound treatment 727513.0 247000.0 0.51 688120.0 231000.0 0.5 0.7134 0.9999 1982236 ChemDiv1_026354 CC(C)CC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N21 compound treatment 735138.0 255000.0 0.53 718923.0 261000.0 0.57 0.7717 0.9993 1982237 ChemDiv1_026355 Cc1ccc(cc1)N2C3=C(C(C4=C2CC(C)(C)CC4=O)c5ccccc5)C(=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N22 compound treatment 712654.0 232000.0 0.48 665275.0 208000.0 0.45 0.6567 0.9995 1339836 ChemDiv1_026356 NC(=O)C1CCN(Cn2nc(c3ccccc3)n(c4ccccc4)c2=S)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N23 mock treatment 695454.0 215000.0 0.44 699066.0 242000.0 0.52 0.6833 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 N24 mock treatment 383221.0 -97400.0 -0.2 382959.0 -74500.0 -0.16 -0.2562 -0.9941 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O01 compound treatment 636274.0 156000.0 0.32 572632.0 115000.0 0.25 0.4035 0.9921 1982238 ChemDiv1_026357 S=c1sc2SC3CCCCCCCCCCC3Sc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O02 compound treatment 640934.0 160000.0 0.33 605138.0 148000.0 0.32 0.46 0.9998 1172583 ChemDiv1_026358 CC(C)(C)C1CC=C2C(C1)C(c3c[nH]c4ccccc34)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O03 compound treatment 695755.0 215000.0 0.44 651972.0 194000.0 0.42 0.6117 0.9996 1982239 ChemDiv1_026359 CCCCN1/C(=C\2/SC(=S)N(C)C2=O)/Sc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O04 compound treatment 942791.0 462000.0 0.95 781653.0 324000.0 0.7 1.1708 0.9886 1982240 ChemDiv1_026360 Fc1ccc([C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5)c(F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O05 compound treatment 684664.0 204000.0 0.42 630199.0 173000.0 0.37 0.5622 0.9982 1982241 ChemDiv1_026361 Brc1ccc(cc1)C2(SC3(SC(=NN3c4ccccc4)C(=O)c5ccccc5)c6ccccc62)c7ccc(Br)cc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O06 compound treatment 672948.0 192000.0 0.4 631618.0 174000.0 0.38 0.5473 0.9997 1783166 ChemDiv1_026362 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O07 compound treatment 897096.0 417000.0 0.86 824485.0 367000.0 0.79 1.1696 0.9992 1982242 ChemDiv1_026363 COc1ccc(cc1)N2C(N(N=C2C(=O)C)c3ccccc3)c4ccccc4OCc5c(Cl)cccc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O08 compound treatment 660309.0 180000.0 0.37 610644.0 153000.0 0.33 0.4967 0.9984 1982243 ChemDiv1_026364 Cc1ccc(cc1C)C2=C/C(=C\3/c4ccccc4-c5ncccc35)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O09 compound treatment 760021.0 279000.0 0.58 717085.0 260000.0 0.56 0.8052 0.9999 1982244 ChemDiv1_026365 Fc1ccc(/C=C/2\C(=O)N(C3=C2C(N(C3=O)c4ccccc4)c5ccc(Br)cc5)c6ccccc6)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O10 compound treatment 689930.0 209000.0 0.43 617885.0 160000.0 0.35 0.551 0.9941 1255478 ChemDiv1_026366 COc1cccc(C2C3CC(CC=C3C(=C(N)C2(C#N)C#N)C#N)C(C)(C)C)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O11 compound treatment 688110.0 208000.0 0.43 638733.0 181000.0 0.39 0.5803 0.999 1377721 ChemDiv1_026367 CN1C2C(N(C)C1=O)N(CCNC(=O)C)C(=O)N2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O12 compound treatment 621478.0 141000.0 0.29 621006.0 164000.0 0.35 0.4559 0.9953 1982245 ChemDiv1_026368 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O13 compound treatment 709964.0 229000.0 0.47 656960.0 199000.0 0.43 0.6401 0.9989 1982246 ChemDiv1_026369 Fc1cccc2[nH]c3nc(S)nnc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O14 compound treatment 679740.0 199000.0 0.41 639800.0 182000.0 0.39 0.5697 0.9998 1982247 ChemDiv1_026370 CCOC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)ccc4N(C(=O)CC)C3(C)C)C(=O)OCC)C(=O)OCC)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O15 compound treatment 734959.0 254000.0 0.53 668983.0 211000.0 0.46 0.695 0.9977 1612765 ChemDiv1_026371 CC(=O)Oc1ccc2c(OC(CC32CC(C)(C)NC(=O)N3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O16 compound treatment 675634.0 195000.0 0.4 629853.0 172000.0 0.37 0.5485 0.9993 1317172 ChemDiv1_026372 CCC(C)C(=O)N1c2ccccc2C(C)(CC1(C)C)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O17 compound treatment 4240734.0 3760000.0 7.76 3604888.0 3150000.0 6.81 10.3055 0.9979 1717689 ChemDiv1_026373 Cn1c(=O)c(NC2CCCCC2)c3-c4ccccc4C(=O)c5cccc1c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O18 compound treatment 694034.0 213000.0 0.44 631693.0 174000.0 0.38 0.5782 0.997 1982248 ChemDiv1_026374 COC(=O)C1=C(SC2(S1)C(=C(SC3=C2c4cc(C)c(C)cc4N(C(=O)c5ccc6OCOc6c5)C3(C)C)C(=O)OC)C(=O)OC)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O19 compound treatment 724063.0 243000.0 0.5 660146.0 203000.0 0.44 0.6655 0.9977 1982249 ChemDiv1_026375 Cc1ccc(C2SCc3cc(C)c(C)cc3CS2)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O20 compound treatment 690672.0 210000.0 0.43 621434.0 164000.0 0.35 0.5575 0.995 1581273 ChemDiv1_026376 S=C(Nc1ccccc1)N2CCn3c4C2CCCc4c5cc(ccc35)C6CCCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O21 compound treatment 733122.0 253000.0 0.52 663939.0 206000.0 0.45 0.6846 0.9971 1982250 ChemDiv1_026377 CCc1ccc(NC2=CC(N(C2=O)c3ccc(CC)cc3)c4ccc(cc4)C(C)(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O22 compound treatment 698378.0 218000.0 0.45 610957.0 153000.0 0.33 0.5528 0.9889 1982251 ChemDiv1_026378 CCN1/C(=C/2\SC(=S)N(Cc3ccccc3)C2=O)/Sc4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O23 mock treatment 707331.0 227000.0 0.47 611685.0 154000.0 0.33 0.5669 0.9862 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 O24 mock treatment 419966.0 -60600.0 -0.13 414793.0 -42700.0 -0.09 -0.1539 -0.9889 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P01 compound treatment 627940.0 147000.0 0.3 557256.0 99800.0 0.22 0.3678 0.9859 1982252 ChemDiv1_026379 CCCCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P02 compound treatment 634071.0 153000.0 0.32 580073.0 123000.0 0.27 0.4116 0.9961 1982253 ChemDiv1_026380 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(Cc3ccccc3)c4ccc(C)cc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P03 compound treatment 638222.0 158000.0 0.33 600125.0 143000.0 0.31 0.4484 0.9997 1482407 ChemDiv1_026381 CCCn1c(=O)c(=C2C=Cc3ccccc3N2CC)sc1=C4SC(=S)N(C4=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P04 compound treatment 673117.0 193000.0 0.4 624773.0 167000.0 0.36 0.537 0.9989 1245339 ChemDiv1_026382 Fc1ccc(CC(=O)Nc2ccc3OC4(CCCCC4)Oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P05 compound treatment 635880.0 155000.0 0.32 608476.0 151000.0 0.33 0.4577 1.0 1982254 ChemDiv1_026383 CCc1ccc(cc1)C2(SC3(SC(=NN3c4ccc(Br)cc4)C(=O)C)c5ccccc52)c6ccc(CC)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P06 compound treatment 661105.0 181000.0 0.37 596767.0 139000.0 0.3 0.4766 0.9945 1982255 ChemDiv1_026384 CC(=O)C1=NN(c2ccccc2)C3(CCC(=NN3c4ccccc4)c5ccccc5)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P07 compound treatment 646525.0 166000.0 0.34 613267.0 156000.0 0.34 0.4806 1.0 1209872 ChemDiv1_026385 CC1CN(C=O)c2ccccc2N(Cc3ccccc3)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P08 compound treatment 636156.0 156000.0 0.32 610208.0 153000.0 0.33 0.4608 0.9999 1982256 ChemDiv1_026386 CSCCC1(NC(C2C1C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P09 compound treatment 716558.0 236000.0 0.49 698671.0 241000.0 0.52 0.7135 0.9994 1948831 ChemDiv1_026387 CN(C)c1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P10 compound treatment 659420.0 179000.0 0.37 609914.0 152000.0 0.33 0.4943 0.9984 1982257 ChemDiv1_026388 COc1cc(ccc1O)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P11 compound treatment 640543.0 160000.0 0.33 626525.0 169000.0 0.37 0.4922 0.9987 1539269 ChemDiv1_026389 CCOC(=O)c1cccc(c1)N2C(=O)C3C(C2=O)C4(CC)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P12 compound treatment 677037.0 196000.0 0.41 628430.0 171000.0 0.37 0.5483 0.9989 1982258 ChemDiv1_026390 Cc1ccc(cc1)c2cn3nc(C)c(C)nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P13 compound treatment 641727.0 161000.0 0.33 599939.0 142000.0 0.31 0.4532 0.9993 1215478 ChemDiv1_026391 CC(=O)Nc1ccc(Nc2coc3ccc4c(C)cc(=O)oc4c23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P14 compound treatment 663916.0 183000.0 0.38 617244.0 160000.0 0.35 0.5121 0.999 1524122 ChemDiv1_026392 Cc1ccc(cc1Cl)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P15 compound treatment 679257.0 199000.0 0.41 611147.0 154000.0 0.33 0.5251 0.9946 1982259 ChemDiv1_026393 CN1C(NNC(=S)N)C(NNC(=S)N)N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P16 compound treatment 717634.0 237000.0 0.49 658970.0 201000.0 0.44 0.6543 0.9983 1982260 ChemDiv1_026394 CCCCCCc1c(nc2nc(c3ccccc3)c(nn12)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P17 compound treatment 685846.0 205000.0 0.42 624951.0 167000.0 0.36 0.5559 0.997 1129550 ChemDiv1_026395 OC1=C(C(N(C1=O)c2ccccn2)c3cccnc3)C(=O)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P18 compound treatment 669020.0 188000.0 0.39 647536.0 190000.0 0.41 0.5659 0.9996 1685206 ChemDiv1_026396 COc1ccc(Cl)cc1S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3cc(Cl)ccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P19 compound treatment 679664.0 199000.0 0.41 623368.0 166000.0 0.36 0.5444 0.9977 1212705 ChemDiv1_026397 COc1ccc(cc1OC)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P20 compound treatment 662867.0 182000.0 0.38 600159.0 143000.0 0.31 0.4844 0.9952 1374798 ChemDiv1_026398 COc1ccc(cc1O)C(=O)OC2CC(=CCC3(C)CCC(O)(C(C)C)C23)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P21 compound treatment 682934.0 202000.0 0.42 603133.0 146000.0 0.32 0.5182 0.9904 1390234 ChemDiv1_026399 Cn1c2NC3=C(C(c4ccc(Cl)cc4Cl)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P22 compound treatment 682726.0 202000.0 0.42 621931.0 164000.0 0.36 0.5467 0.9969 1679305 ChemDiv1_026400 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(O)cc4)ccc5ncccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P23 mock treatment 658592.0 178000.0 0.37 584135.0 127000.0 0.27 0.4536 0.9896 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.661 P24 mock treatment 289834.0 -191000.0 -0.39 437087.0 -20400.0 -0.04 -0.3097 -0.7816 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A01 compound treatment 623296.0 166000.0 0.34 555473.0 108000.0 0.23 0.4076 0.9825 1982261 ChemDiv1_026753 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4cccc(c4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A02 compound treatment 612279.0 155000.0 0.32 570007.0 122000.0 0.26 0.4137 0.9956 1982262 ChemDiv1_026754 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A03 compound treatment 632732.0 176000.0 0.36 588019.0 140000.0 0.3 0.4711 0.9962 1982263 ChemDiv1_026755 CCc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4ccccc4C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A04 compound treatment 628054.0 171000.0 0.35 576976.0 129000.0 0.28 0.4474 0.9935 1982264 ChemDiv1_026756 Cc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A05 compound treatment 624915.0 168000.0 0.35 600458.0 153000.0 0.33 0.4788 0.9997 1982265 ChemDiv1_026757 CCc1ccc(N/C(=C(/C#N)\C(=O)N)/SC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A06 compound treatment 667234.0 210000.0 0.43 623469.0 176000.0 0.38 0.5758 0.9979 1982266 ChemDiv1_026758 Cc1ccc(C)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A07 compound treatment 683810.0 227000.0 0.47 653738.0 206000.0 0.45 0.6463 0.9997 1982267 ChemDiv1_026759 Cc1ccccc1CS/C(=C(\C#N)/C(=O)NCc2ccco2)/Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A08 compound treatment 654305.0 197000.0 0.41 629443.0 182000.0 0.39 0.566 0.9999 1982268 ChemDiv1_026760 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cc(OC)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A09 compound treatment 668270.0 211000.0 0.44 632927.0 185000.0 0.4 0.5917 0.9991 1982269 ChemDiv1_026761 CCc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A10 compound treatment 651589.0 194000.0 0.4 639948.0 192000.0 0.42 0.5781 0.9998 1982270 ChemDiv1_026762 CCc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A11 compound treatment 644887.0 188000.0 0.39 631920.0 184000.0 0.4 0.5561 0.9999 1982271 ChemDiv1_026763 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccc(C)cc3C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A12 compound treatment 677226.0 220000.0 0.45 629997.0 182000.0 0.39 0.6003 0.9976 1982272 ChemDiv1_026764 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A13 compound treatment 683089.0 226000.0 0.47 633675.0 186000.0 0.4 0.6145 0.9973 1982273 ChemDiv1_026765 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A14 compound treatment 651237.0 194000.0 0.4 636278.0 189000.0 0.41 0.572 1.0 1982274 ChemDiv1_026766 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A15 compound treatment 669591.0 212000.0 0.44 640930.0 193000.0 0.42 0.6059 0.9997 1982275 ChemDiv1_026767 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A16 compound treatment 669526.0 212000.0 0.44 637198.0 190000.0 0.41 0.6001 0.9995 1982276 ChemDiv1_026768 OC1(C[N+](=C2SCCCN21)c3ccc(Cl)cc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A17 compound treatment 671833.0 215000.0 0.44 653251.0 206000.0 0.45 0.628 1.0 1982277 ChemDiv1_026769 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A18 compound treatment 648319.0 191000.0 0.39 636454.0 189000.0 0.41 0.568 0.9998 1982278 ChemDiv1_026770 COc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A19 compound treatment 662726.0 206000.0 0.42 617430.0 170000.0 0.37 0.5599 0.9974 1982279 ChemDiv1_026771 OC1(C[N+](=C2SCCN21)c3ccccc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A20 compound treatment 643606.0 186000.0 0.38 608680.0 161000.0 0.35 0.5186 0.9988 1982280 ChemDiv1_026772 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A21 compound treatment 625465.0 168000.0 0.35 596886.0 149000.0 0.32 0.4741 0.9993 1982281 ChemDiv1_026773 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A22 compound treatment 615336.0 158000.0 0.33 572309.0 125000.0 0.27 0.4217 0.9955 1982282 ChemDiv1_026774 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A23 mock treatment 580206.0 123000.0 0.25 555336.0 108000.0 0.23 0.3444 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 A24 mock treatment 205171.0 -252000.0 -0.52 209705.0 -238000.0 -0.51 -0.732 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B01 compound treatment 654594.0 197000.0 0.41 569375.0 122000.0 0.26 0.4745 0.9778 1982283 ChemDiv1_026775 Cc1cccc([N+]2=C3CCCCN3C(O)(C2)c4ccc(F)cc4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B02 compound treatment 688832.0 232000.0 0.48 613286.0 166000.0 0.36 0.5917 0.99 1529683 ChemDiv1_026776 COc1ccc(Cl)cc1NC(=O)c2c(NCc3cccnc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B03 compound treatment 716127.0 259000.0 0.53 656987.0 209000.0 0.45 0.6984 0.9966 1982284 ChemDiv1_026777 CCc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B04 compound treatment 704465.0 247000.0 0.51 666848.0 219000.0 0.47 0.6965 0.9993 1671525 ChemDiv1_026778 CCn1cnc2sc(C(=O)N3C(C)CCc4cc(F)ccc34)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B05 compound treatment 742268.0 285000.0 0.59 674185.0 227000.0 0.49 0.7629 0.9959 1982285 ChemDiv1_026779 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B06 compound treatment 721147.0 264000.0 0.54 656938.0 209000.0 0.45 0.7057 0.9958 1349933 ChemDiv1_026780 Cc1c(sc2ncn(Cc3ccccc3F)c(=O)c12)C(=O)N4CCCc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B07 compound treatment 761791.0 305000.0 0.63 708338.0 261000.0 0.56 0.8437 0.9985 1982286 ChemDiv1_026781 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B08 compound treatment 731949.0 275000.0 0.57 676234.0 229000.0 0.49 0.751 0.9977 1982287 ChemDiv1_026782 C(Cc1ccccc1)Sc2nnc(c3ccncc3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B09 compound treatment 751593.0 294000.0 0.61 708884.0 261000.0 0.57 0.8296 0.9994 1982288 ChemDiv1_026783 Cc1ccccc1[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B10 compound treatment 724047.0 267000.0 0.55 691706.0 244000.0 0.53 0.7631 0.9998 1702960 ChemDiv1_026784 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N3CCc4ccccc4C3CN5C(=O)c6ccccc6C5=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B11 compound treatment 753124.0 296000.0 0.61 662853.0 215000.0 0.47 0.7614 0.9911 1221879 ChemDiv1_026785 Brc1cccc(Cn2cnc3sc4CCCCc4c3c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B12 compound treatment 746749.0 290000.0 0.6 673699.0 226000.0 0.49 0.7687 0.9951 1170563 ChemDiv1_026786 Fc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B13 compound treatment 770212.0 313000.0 0.65 688699.0 241000.0 0.52 0.8259 0.9944 1982289 ChemDiv1_026787 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccccc4O)/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B14 compound treatment 736524.0 279000.0 0.58 678488.0 231000.0 0.5 0.7611 0.9975 1145210 ChemDiv1_026788 Fc1ccc(cc1F)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B15 compound treatment 753082.0 296000.0 0.61 724601.0 277000.0 0.6 0.8558 1.0 1296208 ChemDiv1_026789 CCN(CC)C(=O)CSc1nc2ccccc2nc1Cc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B16 compound treatment 722480.0 265000.0 0.55 694668.0 247000.0 0.53 0.7654 0.9999 1212626 ChemDiv1_026790 Clc1ccc(s1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B17 compound treatment 780655.0 323000.0 0.67 723038.0 275000.0 0.6 0.8937 0.9984 1982290 ChemDiv1_026791 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCCN4CCOCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B18 compound treatment 781824.0 325000.0 0.67 767169.0 320000.0 0.69 0.9629 0.9999 1982291 ChemDiv1_026792 COc1cc(OC)c(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B19 compound treatment 728920.0 272000.0 0.56 677811.0 230000.0 0.5 0.749 0.9983 1982292 ChemDiv1_026793 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])cc1F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B20 compound treatment 768588.0 311000.0 0.64 751137.0 304000.0 0.66 0.9191 0.9999 1982293 ChemDiv1_026794 COc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B21 compound treatment 744146.0 287000.0 0.59 697328.0 250000.0 0.54 0.8011 0.999 1289262 ChemDiv1_026795 COc1ccc(OC)c(NC(=O)c2c(NCc3cccc(OC)c3OC)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B22 compound treatment 678707.0 222000.0 0.46 637426.0 190000.0 0.41 0.6139 0.9986 1454003 ChemDiv1_026796 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B23 mock treatment 680234.0 223000.0 0.46 634016.0 186000.0 0.4 0.6109 0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 B24 mock treatment 241340.0 -216000.0 -0.45 222774.0 -225000.0 -0.49 -0.6592 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C01 compound treatment 632898.0 176000.0 0.36 573687.0 126000.0 0.27 0.4494 0.9902 1982294 ChemDiv1_026797 CCc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4cccc(c4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C02 compound treatment 649973.0 193000.0 0.4 636102.0 189000.0 0.41 0.5699 0.9999 1982295 ChemDiv1_026798 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C03 compound treatment 668672.0 211000.0 0.44 661495.0 214000.0 0.46 0.636 0.9996 1982296 ChemDiv1_026799 CCc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4cccc(F)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C04 compound treatment 646525.0 189000.0 0.39 651079.0 203000.0 0.44 0.5878 0.9982 1982297 ChemDiv1_026800 COc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C05 compound treatment 691107.0 234000.0 0.48 663003.0 215000.0 0.47 0.6711 0.9998 1982298 ChemDiv1_026801 CCc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccccc2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C06 compound treatment 693536.0 236000.0 0.49 693859.0 246000.0 0.53 0.7219 0.999 1982299 ChemDiv1_026802 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C07 compound treatment 711403.0 254000.0 0.52 676979.0 229000.0 0.5 0.7221 0.9996 1982300 ChemDiv1_026803 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C08 compound treatment 724020.0 267000.0 0.55 717608.0 270000.0 0.58 0.8027 0.9996 1982301 ChemDiv1_026804 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C09 compound treatment 714363.0 257000.0 0.53 717043.0 269000.0 0.58 0.7878 0.9989 1982302 ChemDiv1_026805 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C10 compound treatment 704316.0 247000.0 0.51 711985.0 264000.0 0.57 0.7653 0.9984 1982303 ChemDiv1_026806 CCc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C11 compound treatment 718308.0 261000.0 0.54 713464.0 266000.0 0.58 0.788 0.9995 1982304 ChemDiv1_026807 Cc1ccc(CS/C(=C(\C#N)/C(=O)NCc2ccco2)/Nc3ccccc3C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C12 compound treatment 697510.0 240000.0 0.5 695520.0 248000.0 0.54 0.7302 0.9992 1982305 ChemDiv1_026808 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C13 compound treatment 731472.0 274000.0 0.57 720447.0 273000.0 0.59 0.8179 0.9998 1982306 ChemDiv1_026809 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C14 compound treatment 731644.0 274000.0 0.57 705170.0 258000.0 0.56 0.7948 1.0 1982307 ChemDiv1_026810 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C15 compound treatment 746200.0 289000.0 0.6 721024.0 273000.0 0.59 0.8403 1.0 1982308 ChemDiv1_026811 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C16 compound treatment 735194.0 278000.0 0.57 720329.0 273000.0 0.59 0.8232 0.9999 1982309 ChemDiv1_026812 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C17 compound treatment 733624.0 276000.0 0.57 711335.0 264000.0 0.57 0.8071 1.0 1982310 ChemDiv1_026813 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C18 compound treatment 689734.0 233000.0 0.48 671011.0 223000.0 0.48 0.6814 1.0 1982311 ChemDiv1_026814 Cc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C19 compound treatment 723830.0 267000.0 0.55 665679.0 218000.0 0.47 0.723 0.9971 1982312 ChemDiv1_026815 COc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C20 compound treatment 686969.0 230000.0 0.47 673530.0 226000.0 0.49 0.6812 0.9999 1982313 ChemDiv1_026816 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C21 compound treatment 696498.0 239000.0 0.49 679272.0 232000.0 0.5 0.7039 1.0 1982314 ChemDiv1_026817 OC1(C[N+](=C2SCCCN21)c3ccc(Br)cc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C22 compound treatment 658947.0 202000.0 0.42 644504.0 197000.0 0.43 0.5958 0.9999 1982315 ChemDiv1_026818 COc1ccc(cc1OC)C2(O)C[N+](=C3CCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C23 mock treatment 663054.0 206000.0 0.42 654705.0 207000.0 0.45 0.6175 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 C24 mock treatment 244461.0 -213000.0 -0.44 192406.0 -255000.0 -0.55 -0.7011 -0.9935 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D01 compound treatment 667189.0 210000.0 0.43 579471.0 132000.0 0.29 0.5083 0.9794 1982316 ChemDiv1_026819 CCOc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D02 compound treatment 682070.0 225000.0 0.46 632301.0 185000.0 0.4 0.6109 0.9972 1668904 ChemDiv1_026820 CC1CCCCN1C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D03 compound treatment 703269.0 246000.0 0.51 668297.0 221000.0 0.48 0.697 0.9995 1982317 ChemDiv1_026821 CCc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D04 compound treatment 718116.0 261000.0 0.54 639211.0 192000.0 0.41 0.6741 0.9917 1572813 ChemDiv1_026822 CCn1cnc2sc(C(=O)N3CCC(C)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D05 compound treatment 725675.0 268000.0 0.55 665302.0 218000.0 0.47 0.7251 0.9967 1982318 ChemDiv1_026823 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D06 compound treatment 703689.0 246000.0 0.51 646499.0 199000.0 0.43 0.6642 0.9965 1569450 ChemDiv1_026824 CC1CCc2cc(F)ccc2N1C(=O)c3sc4ncn(Cc5ccccc5Cl)c(=O)c4c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D07 compound treatment 725664.0 268000.0 0.55 697748.0 250000.0 0.54 0.7747 0.9999 1982319 ChemDiv1_026825 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D08 compound treatment 750167.0 293000.0 0.6 690004.0 242000.0 0.52 0.7986 0.9975 1629066 ChemDiv1_026826 Cc1ccc(cc1C)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D09 compound treatment 751201.0 294000.0 0.61 708915.0 261000.0 0.57 0.8291 0.9994 1982320 ChemDiv1_026827 Cc1ccc(c(C)c1)C2(O)C[N+](=C3CCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D10 compound treatment 724031.0 267000.0 0.55 730742.0 283000.0 0.61 0.8228 0.9986 1502805 ChemDiv1_026828 COc1ccc(Br)cc1S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D11 compound treatment 752906.0 296000.0 0.61 674684.0 227000.0 0.49 0.7792 0.9942 1689521 ChemDiv1_026829 CC(C)(C)c1ccc(Cn2cnc3sc4CCCCc4c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D12 compound treatment 721084.0 264000.0 0.54 666364.0 219000.0 0.47 0.72 0.9976 1707699 ChemDiv1_026830 Clc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D13 compound treatment 803219.0 346000.0 0.71 748418.0 301000.0 0.65 0.9655 0.9989 1982321 ChemDiv1_026831 COc1cc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D14 compound treatment 730210.0 273000.0 0.56 680363.0 233000.0 0.5 0.7547 0.9984 1396686 ChemDiv1_026832 O=S(=O)(Cc1ccccc1)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D15 compound treatment 731666.0 274000.0 0.57 685116.0 238000.0 0.51 0.7641 0.9988 1269383 ChemDiv1_026833 COC(=O)CSc1nc2ccccc2nc1Cc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D16 compound treatment 731001.0 274000.0 0.57 704264.0 257000.0 0.56 0.7925 1.0 1513760 ChemDiv1_026834 Fc1ccc(cc1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D17 compound treatment 764162.0 307000.0 0.63 715809.0 268000.0 0.58 0.8586 0.999 1982322 ChemDiv1_026835 COc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D18 compound treatment 760315.0 303000.0 0.63 814926.0 367000.0 0.8 1.0046 0.993 1982323 ChemDiv1_026836 COc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D19 compound treatment 733987.0 277000.0 0.57 701062.0 253000.0 0.55 0.7919 0.9998 1189563 ChemDiv1_026837 O=c1cccc2C3CC(CN(CCC#N)C3)Cn21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D20 compound treatment 721341.0 264000.0 0.55 718971.0 271000.0 0.59 0.8009 0.9993 1982324 ChemDiv1_026838 Cc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D21 compound treatment 722442.0 265000.0 0.55 711775.0 264000.0 0.57 0.7915 0.9998 1525063 ChemDiv1_026839 COc1ccc(OC)c(NC(=O)c2c(NCc3ccc(OC)c(OC)c3)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D22 compound treatment 681391.0 224000.0 0.46 684416.0 237000.0 0.51 0.6897 0.9987 1161196 ChemDiv1_026840 Cc1c(sc2ncn(C)c(=O)c12)C(=O)N3CCN(Cc4ccccc4)CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D23 mock treatment 673305.0 216000.0 0.45 656343.0 209000.0 0.45 0.6349 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 D24 mock treatment 223067.0 -234000.0 -0.48 213936.0 -234000.0 -0.51 -0.6994 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E01 compound treatment 625254.0 168000.0 0.35 580439.0 133000.0 0.29 0.4486 0.9956 1982325 ChemDiv1_026841 CCc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E02 compound treatment 628692.0 171000.0 0.35 620080.0 172000.0 0.37 0.5143 0.9996 1982326 ChemDiv1_026842 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E03 compound treatment 698136.0 241000.0 0.5 671016.0 223000.0 0.48 0.6936 0.9999 1982327 ChemDiv1_026843 Cc1ccccc1CS/C(=C(\C#N)/C(=O)N)/Nc2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E04 compound treatment 689226.0 232000.0 0.48 665605.0 218000.0 0.47 0.6723 1.0 1982328 ChemDiv1_026844 Cc1cccc([N+]2=C3SCCCN3C(O)(C2)c4ccccc4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E05 compound treatment 721422.0 264000.0 0.55 653902.0 206000.0 0.45 0.7014 0.9951 1982329 ChemDiv1_026845 CCc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E06 compound treatment 684916.0 228000.0 0.47 684809.0 237000.0 0.51 0.6954 0.999 1982330 ChemDiv1_026846 Cc1ccc(C)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E07 compound treatment 708743.0 252000.0 0.52 688768.0 241000.0 0.52 0.7363 1.0 1982331 ChemDiv1_026847 Cc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccccc3C)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E08 compound treatment 715464.0 258000.0 0.53 694934.0 247000.0 0.54 0.7555 1.0 1982332 ChemDiv1_026848 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E09 compound treatment 700431.0 243000.0 0.5 707455.0 260000.0 0.56 0.7527 0.9984 1982333 ChemDiv1_026849 Cc1ccc(CS/C(=C(\C#N)/C(=O)N)/Nc2ccccc2C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E10 compound treatment 713080.0 256000.0 0.53 685515.0 238000.0 0.51 0.7376 0.9999 1982334 ChemDiv1_026850 CCc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E11 compound treatment 721897.0 265000.0 0.55 692878.0 245000.0 0.53 0.7618 0.9999 1982335 ChemDiv1_026851 Cc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3cccc(c3)[N+](=O)[O-])cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E12 compound treatment 736687.0 279000.0 0.58 690924.0 243000.0 0.53 0.7804 0.999 1982336 ChemDiv1_026852 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E13 compound treatment 743641.0 286000.0 0.59 675307.0 228000.0 0.49 0.7666 0.9959 1982337 ChemDiv1_026853 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3cccc(c3)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E14 compound treatment 712837.0 256000.0 0.53 687909.0 240000.0 0.52 0.7409 1.0 1982338 ChemDiv1_026854 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E15 compound treatment 726720.0 270000.0 0.56 723591.0 276000.0 0.6 0.8158 0.9994 1982339 ChemDiv1_026855 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E16 compound treatment 703300.0 246000.0 0.51 701673.0 254000.0 0.55 0.7481 0.9992 1982340 ChemDiv1_026856 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E17 compound treatment 718869.0 262000.0 0.54 686886.0 239000.0 0.52 0.7482 0.9998 1982341 ChemDiv1_026857 Cc1ccc(cc1)C2(O)C[N+](=C3SCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E18 compound treatment 705320.0 248000.0 0.51 684198.0 237000.0 0.51 0.7243 1.0 1982342 ChemDiv1_026858 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E19 compound treatment 730033.0 273000.0 0.56 717565.0 270000.0 0.58 0.8114 0.9998 1982343 ChemDiv1_026859 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E20 compound treatment 686827.0 230000.0 0.47 683249.0 236000.0 0.51 0.6958 0.9993 1982344 ChemDiv1_026860 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E21 compound treatment 693929.0 237000.0 0.49 692584.0 245000.0 0.53 0.7205 0.9992 1982345 ChemDiv1_026861 COc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E22 compound treatment 661091.0 204000.0 0.42 681328.0 234000.0 0.51 0.6553 0.9958 1982346 ChemDiv1_026862 COc1ccc(c(F)c1)C2(O)C[N+](=C3CCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E23 mock treatment 653796.0 197000.0 0.41 664835.0 217000.0 0.47 0.6194 0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 E24 mock treatment 221622.0 -236000.0 -0.49 177966.0 -270000.0 -0.58 -0.7565 -0.9959 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F01 compound treatment 658376.0 201000.0 0.42 594777.0 147000.0 0.32 0.5189 0.9914 1982347 ChemDiv1_026863 Cc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F02 compound treatment 689723.0 233000.0 0.48 634512.0 187000.0 0.4 0.6255 0.9964 1729808 ChemDiv1_026864 CCC1CCCCN1C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F03 compound treatment 724618.0 267000.0 0.55 707642.0 260000.0 0.56 0.7883 1.0 1982348 ChemDiv1_026865 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F04 compound treatment 696523.0 239000.0 0.49 655946.0 208000.0 0.45 0.6682 0.999 1730294 ChemDiv1_026866 CCn1cnc2sc(C(=O)N3CCCC(C)C3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F05 compound treatment 739102.0 282000.0 0.58 698995.0 251000.0 0.54 0.7962 0.9994 1982349 ChemDiv1_026867 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F06 compound treatment 742760.0 286000.0 0.59 765363.0 318000.0 0.69 0.9032 0.9971 1185815 ChemDiv1_026868 CC1CCc2cc(F)ccc2N1C(=O)c3sc4ncn(Cc5cccc(F)c5)c(=O)c4c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F07 compound treatment 749387.0 292000.0 0.6 703238.0 256000.0 0.55 0.8178 0.9991 1982350 ChemDiv1_026869 COc1ccc(cc1OC)C2(O)C[N+](=C3CCCCN32)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F08 compound treatment 751476.0 294000.0 0.61 684057.0 236000.0 0.51 0.7914 0.9964 1311316 ChemDiv1_026870 CCc1ccc(cc1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F09 compound treatment 755713.0 299000.0 0.62 714823.0 267000.0 0.58 0.8447 0.9995 1982351 ChemDiv1_026871 COc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F10 compound treatment 779155.0 322000.0 0.66 727754.0 280000.0 0.61 0.8987 0.999 1597583 ChemDiv1_026872 COc1ccc(Cl)cc1S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F11 compound treatment 713476.0 256000.0 0.53 679238.0 232000.0 0.5 0.7286 0.9996 1511565 ChemDiv1_026873 Cc1ccccc1Cn2cnc3sc4CCCCc4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F12 compound treatment 749788.0 293000.0 0.6 726697.0 279000.0 0.6 0.8542 1.0 1389043 ChemDiv1_026874 O=C1N(CC2N(CCc3ccccc23)S(=O)(=O)c4cccs4)C(=O)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F13 compound treatment 760638.0 303000.0 0.63 723379.0 276000.0 0.6 0.865 0.9997 1982352 ChemDiv1_026875 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccccc4Cl)/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F14 compound treatment 717565.0 260000.0 0.54 717693.0 270000.0 0.58 0.7934 0.9991 1593953 ChemDiv1_026876 Fc1ccc(cc1Cl)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F15 compound treatment 748468.0 291000.0 0.6 693271.0 246000.0 0.53 0.8012 0.9981 1982353 ChemDiv1_026877 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCC#N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F16 compound treatment 750348.0 293000.0 0.61 680238.0 233000.0 0.5 0.784 0.9958 1683077 ChemDiv1_026878 Clc1ccc(cc1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F17 compound treatment 769371.0 312000.0 0.64 754372.0 307000.0 0.66 0.9252 0.9999 1982354 ChemDiv1_026879 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F18 compound treatment 945209.0 488000.0 1.01 1023466.0 576000.0 1.25 1.5937 0.9944 1982355 ChemDiv1_026880 COc1cc(OC)c(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F19 compound treatment 739760.0 283000.0 0.58 704049.0 256000.0 0.56 0.8049 0.9997 1982356 ChemDiv1_026881 CCOC(=O)C1CC/C(=C\c2ccccc2)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F20 compound treatment 809947.0 353000.0 0.73 816366.0 369000.0 0.8 1.0793 0.999 1982357 ChemDiv1_026882 COc1ccccc1C2C=C(Nc3nc4ccccc4n23)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F21 compound treatment 744100.0 287000.0 0.59 735676.0 288000.0 0.62 0.8597 0.9997 1982358 ChemDiv1_026883 COc1ccc(OC)c(NC(=O)c2c(NCc3ccc(OC)c(OC)c3OC)sc4CCCCCc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F22 compound treatment 693585.0 236000.0 0.49 665895.0 218000.0 0.47 0.6791 0.9999 1727114 ChemDiv1_026884 CCCN1CCN(CC1)C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F23 mock treatment 676363.0 219000.0 0.45 664826.0 217000.0 0.47 0.6524 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 F24 mock treatment 261194.0 -196000.0 -0.4 187390.0 -260000.0 -0.56 -0.6843 -0.9868 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G01 compound treatment 629619.0 172000.0 0.36 590382.0 143000.0 0.31 0.4702 0.9975 1982359 ChemDiv1_026885 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccccc3C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G02 compound treatment 654678.0 197000.0 0.41 621970.0 174000.0 0.38 0.5551 0.9993 1982360 ChemDiv1_026886 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G03 compound treatment 689748.0 233000.0 0.48 673478.0 226000.0 0.49 0.6852 1.0 1982361 ChemDiv1_026887 Cc1ccccc1N/C(=C(/C#N)\C(=O)N)/SCc2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G04 compound treatment 676424.0 219000.0 0.45 661676.0 214000.0 0.46 0.6476 0.9999 1982362 ChemDiv1_026888 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G05 compound treatment 688763.0 232000.0 0.48 715421.0 268000.0 0.58 0.7479 0.9954 1982363 ChemDiv1_026889 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(Cl)cc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G06 compound treatment 692137.0 235000.0 0.48 657703.0 210000.0 0.45 0.6645 0.9995 1982364 ChemDiv1_026890 Cc1ccc(C)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G07 compound treatment 731029.0 274000.0 0.57 680329.0 233000.0 0.5 0.7559 0.9983 1982365 ChemDiv1_026891 Cc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccc(Cl)cc3)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G08 compound treatment 697550.0 240000.0 0.5 666806.0 219000.0 0.47 0.6863 0.9998 1982366 ChemDiv1_026892 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G09 compound treatment 714701.0 257000.0 0.53 664620.0 217000.0 0.47 0.708 0.9981 1982367 ChemDiv1_026893 Cc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccccc2C)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G10 compound treatment 719943.0 263000.0 0.54 692888.0 245000.0 0.53 0.7589 0.9999 1982368 ChemDiv1_026894 CCc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G11 compound treatment 743625.0 286000.0 0.59 701032.0 253000.0 0.55 0.806 0.9993 1982369 ChemDiv1_026895 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G12 compound treatment 760291.0 303000.0 0.63 701179.0 254000.0 0.55 0.8305 0.9979 1982370 ChemDiv1_026896 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G13 compound treatment 762375.0 305000.0 0.63 702486.0 255000.0 0.55 0.8356 0.9978 1982371 ChemDiv1_026897 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccc(C)cc3C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G14 compound treatment 737961.0 281000.0 0.58 732266.0 285000.0 0.62 0.8455 0.9995 1982372 ChemDiv1_026898 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)cc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G15 compound treatment 752613.0 295000.0 0.61 721746.0 274000.0 0.59 0.8508 0.9999 1982373 ChemDiv1_026899 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G16 compound treatment 707891.0 251000.0 0.52 665670.0 218000.0 0.47 0.6997 0.9989 1982374 ChemDiv1_026900 Cc1ccc(cc1)C2(O)C[N+](=C3SCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G17 compound treatment 731805.0 275000.0 0.57 734478.0 287000.0 0.62 0.8399 0.999 1982375 ChemDiv1_026901 OC1(C[N+](=C2SCCN21)c3ccccc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G18 compound treatment 724482.0 267000.0 0.55 671393.0 224000.0 0.48 0.7327 0.9979 1982376 ChemDiv1_026902 Cc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G19 compound treatment 723000.0 266000.0 0.55 704743.0 257000.0 0.56 0.7815 1.0 1982377 ChemDiv1_026903 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G20 compound treatment 698408.0 241000.0 0.5 696448.0 249000.0 0.54 0.7329 0.9992 1982378 ChemDiv1_026904 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G21 compound treatment 693655.0 236000.0 0.49 702312.0 255000.0 0.55 0.735 0.9982 1982379 ChemDiv1_026905 OC1(C[N+](=C2SCCCN21)c3ccc(Br)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G22 compound treatment 681410.0 224000.0 0.46 662904.0 215000.0 0.47 0.6568 1.0 1982380 ChemDiv1_026906 COc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G23 mock treatment 663925.0 207000.0 0.43 643993.0 196000.0 0.43 0.6023 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 G24 mock treatment 221109.0 -236000.0 -0.49 182793.0 -265000.0 -0.57 -0.7499 -0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H01 compound treatment 640913.0 184000.0 0.38 589426.0 142000.0 0.31 0.4852 0.9945 1982381 ChemDiv1_026907 Cc1ccc(C)c(c1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H02 compound treatment 676543.0 219000.0 0.45 619670.0 172000.0 0.37 0.5835 0.9953 1633885 ChemDiv1_026908 CC1CCN(CC1)C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H03 compound treatment 715671.0 258000.0 0.53 676790.0 229000.0 0.5 0.7281 0.9993 1982382 ChemDiv1_026909 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H04 compound treatment 687356.0 230000.0 0.48 664492.0 217000.0 0.47 0.6679 1.0 1728913 ChemDiv1_026910 CCn1cnc2sc(C(=O)N3CCCc4ccccc34)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H05 compound treatment 714542.0 257000.0 0.53 685106.0 238000.0 0.51 0.7391 0.9999 1982383 ChemDiv1_026911 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H06 compound treatment 696156.0 239000.0 0.49 633554.0 186000.0 0.4 0.6334 0.9949 1982384 ChemDiv1_026912 Brc1ccc(cc1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H07 compound treatment 725948.0 269000.0 0.55 706249.0 259000.0 0.56 0.7881 1.0 1982385 ChemDiv1_026913 Cc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H08 compound treatment 717202.0 260000.0 0.54 681574.0 234000.0 0.51 0.7376 0.9996 1449629 ChemDiv1_026914 Cc1c(Cl)cccc1n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H09 compound treatment 736024.0 279000.0 0.58 708333.0 261000.0 0.56 0.806 1.0 1982386 ChemDiv1_026915 CCOc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H10 compound treatment 742280.0 285000.0 0.59 697616.0 250000.0 0.54 0.7988 0.9991 1448021 ChemDiv1_026916 Fc1ccc(c(F)c1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H11 compound treatment 756050.0 299000.0 0.62 685320.0 238000.0 0.51 0.8001 0.9959 1541057 ChemDiv1_026917 Fc1cccc(Cl)c1Cn2cnc3sc4CCCCc4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H12 compound treatment 742143.0 285000.0 0.59 681430.0 234000.0 0.51 0.7738 0.9972 1982387 ChemDiv1_026918 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H13 compound treatment 745226.0 288000.0 0.59 684286.0 237000.0 0.51 0.7827 0.9972 1982388 ChemDiv1_026919 COc1ccc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H14 compound treatment 725337.0 268000.0 0.55 668871.0 221000.0 0.48 0.73 0.9974 1505842 ChemDiv1_026920 COc1ccc(Br)cc1S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H15 compound treatment 727935.0 271000.0 0.56 709708.0 262000.0 0.57 0.7963 1.0 1982389 ChemDiv1_026921 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H16 compound treatment 712138.0 255000.0 0.53 680119.0 233000.0 0.5 0.728 0.9998 1664055 ChemDiv1_026922 Cc1ccc(C)c(c1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H17 compound treatment 729460.0 272000.0 0.56 702475.0 255000.0 0.55 0.7875 1.0 1982390 ChemDiv1_026923 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCC(=O)Nc4ccc(F)cc4F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H18 compound treatment 854481.0 397000.0 0.82 915754.0 468000.0 1.01 1.2964 0.9945 1982391 ChemDiv1_026924 COc1ccc(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H19 compound treatment 692485.0 235000.0 0.49 696729.0 249000.0 0.54 0.7247 0.9986 1982392 ChemDiv1_026925 COc1ccc(NC(=O)/C=C/C(=O)O)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H20 compound treatment 821321.0 364000.0 0.75 877526.0 430000.0 0.93 1.1895 0.9944 1982393 ChemDiv1_026926 COc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H21 compound treatment 694484.0 237000.0 0.49 723428.0 276000.0 0.6 0.7685 0.9952 1320369 ChemDiv1_026927 COc1ccc(NC(=O)c2c(NCc3cccc(OC)c3OC)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H22 compound treatment 656419.0 199000.0 0.41 670708.0 223000.0 0.48 0.6323 0.9968 1337777 ChemDiv1_026928 CC1CC(C)CN(C1)C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H23 mock treatment 660503.0 203000.0 0.42 649147.0 202000.0 0.44 0.6052 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 H24 mock treatment 212658.0 -245000.0 -0.5 211213.0 -236000.0 -0.51 -0.7187 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I01 compound treatment 631316.0 174000.0 0.36 585184.0 138000.0 0.3 0.4647 0.9956 1982394 ChemDiv1_026929 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3cccc(c3)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I02 compound treatment 666161.0 209000.0 0.43 612520.0 165000.0 0.36 0.5574 0.9956 1982395 ChemDiv1_026930 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I03 compound treatment 684334.0 227000.0 0.47 658273.0 211000.0 0.46 0.654 0.9999 1982396 ChemDiv1_026931 Cc1ccccc1N/C(=C(/C#N)\C(=O)N)/SCc2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I04 compound treatment 690691.0 233000.0 0.48 658857.0 211000.0 0.46 0.6642 0.9997 1982397 ChemDiv1_026932 Cc1cccc([N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-])c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I05 compound treatment 715979.0 259000.0 0.53 665560.0 218000.0 0.47 0.7113 0.9981 1982398 ChemDiv1_026933 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(C)cc2C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I06 compound treatment 769499.0 312000.0 0.64 654461.0 207000.0 0.45 0.7725 0.9841 1982399 ChemDiv1_026934 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I07 compound treatment 739130.0 282000.0 0.58 688287.0 241000.0 0.52 0.7799 0.9985 1982400 ChemDiv1_026935 Cc1ccc(CS/C(=C(\C#N)/C(=O)NCc2ccco2)/Nc3ccc(C)c(C)c3)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I08 compound treatment 731527.0 274000.0 0.57 671263.0 224000.0 0.48 0.7427 0.997 1982401 ChemDiv1_026936 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I09 compound treatment 701878.0 245000.0 0.51 679702.0 232000.0 0.5 0.7124 1.0 1982402 ChemDiv1_026937 CCOc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I10 compound treatment 701628.0 244000.0 0.5 671267.0 224000.0 0.48 0.6991 0.9998 1982403 ChemDiv1_026938 CCc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)cc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I11 compound treatment 734892.0 278000.0 0.57 665340.0 218000.0 0.47 0.7386 0.9953 1982404 ChemDiv1_026939 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I12 compound treatment 726232.0 269000.0 0.56 668644.0 221000.0 0.48 0.731 0.9972 1982405 ChemDiv1_026940 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I13 compound treatment 756969.0 300000.0 0.62 691919.0 244000.0 0.53 0.8115 0.9969 1982406 ChemDiv1_026941 COc1cccc(N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I14 compound treatment 721389.0 264000.0 0.55 670997.0 223000.0 0.48 0.7275 0.9982 1982407 ChemDiv1_026942 OC1(C[N+](=C2SCCCN21)c3ccc(Cl)cc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I15 compound treatment 732349.0 275000.0 0.57 705206.0 258000.0 0.56 0.7959 1.0 1982408 ChemDiv1_026943 CCOc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccccc2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I16 compound treatment 706306.0 249000.0 0.51 691820.0 244000.0 0.53 0.7374 0.9999 1982409 ChemDiv1_026944 Cc1ccccc1[N+]2=C3SCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I17 compound treatment 720980.0 264000.0 0.54 731744.0 284000.0 0.62 0.8199 0.9982 1982410 ChemDiv1_026945 COc1ccc(cc1)C2(O)C[N+](=C3SCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I18 compound treatment 710743.0 254000.0 0.52 692843.0 245000.0 0.53 0.7454 1.0 1982411 ChemDiv1_026946 Cc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I19 compound treatment 721449.0 264000.0 0.55 691101.0 244000.0 0.53 0.7584 0.9999 1982412 ChemDiv1_026947 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I20 compound treatment 686969.0 230000.0 0.47 677189.0 230000.0 0.5 0.6868 0.9997 1982413 ChemDiv1_026948 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I21 compound treatment 705459.0 248000.0 0.51 678560.0 231000.0 0.5 0.7159 0.9999 1982414 ChemDiv1_026949 OC1(C[N+](=C2SCCCN21)c3ccc(Br)cc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I22 compound treatment 655030.0 198000.0 0.41 661245.0 214000.0 0.46 0.6158 0.9981 1982415 ChemDiv1_026950 COc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I23 mock treatment 654239.0 197000.0 0.41 641672.0 194000.0 0.42 0.5846 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 I24 mock treatment 244838.0 -212000.0 -0.44 182102.0 -265000.0 -0.57 -0.7163 -0.9911 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J01 compound treatment 645104.0 188000.0 0.39 601067.0 153000.0 0.33 0.5092 0.997 1982416 ChemDiv1_026951 COc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J02 compound treatment 674208.0 217000.0 0.45 628210.0 181000.0 0.39 0.5932 0.9977 1701969 ChemDiv1_026952 CCOC(=O)c1c(NC(=O)c2ccccc2F)sc3CN(CCc13)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J03 compound treatment 706001.0 249000.0 0.51 687757.0 240000.0 0.52 0.7307 1.0 1982417 ChemDiv1_026953 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J04 compound treatment 680886.0 224000.0 0.46 652942.0 205000.0 0.44 0.6408 0.9998 1400654 ChemDiv1_026954 CCCn1cnc2sc(C(=O)NCCN3CCOCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J05 compound treatment 724286.0 267000.0 0.55 706368.0 259000.0 0.56 0.7859 1.0 1982418 ChemDiv1_026955 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J06 compound treatment 724667.0 267000.0 0.55 649336.0 202000.0 0.44 0.6992 0.9932 1353397 ChemDiv1_026956 S=c1[nH]nc(c2ccco2)n1c3ccc(Oc4ccccc4)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J07 compound treatment 746611.0 289000.0 0.6 726516.0 279000.0 0.6 0.8493 1.0 1982419 ChemDiv1_026957 Cc1ccccc1[N+]2=C3CCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J08 compound treatment 735256.0 278000.0 0.57 671449.0 224000.0 0.48 0.7485 0.9964 1982420 ChemDiv1_026958 N#CCCSc1nnc(c2ccncc2)n1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J09 compound treatment 741943.0 285000.0 0.59 695630.0 248000.0 0.54 0.7952 0.999 1982421 ChemDiv1_026959 Cc1cccc(c1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J10 compound treatment 727520.0 270000.0 0.56 688857.0 241000.0 0.52 0.7638 0.9995 1982422 ChemDiv1_026960 Cc1ccc(cc1S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J11 compound treatment 700299.0 243000.0 0.5 694893.0 247000.0 0.54 0.7333 0.9995 1247464 ChemDiv1_026961 Fc1ccccc1Cn2cnc3sc4CCCCc4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J12 compound treatment 752765.0 296000.0 0.61 703407.0 256000.0 0.55 0.8229 0.9988 1288201 ChemDiv1_026962 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J13 compound treatment 753065.0 296000.0 0.61 704682.0 257000.0 0.56 0.8253 0.9989 1289375 ChemDiv1_026963 Fc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J14 compound treatment 729984.0 273000.0 0.56 693042.0 245000.0 0.53 0.7738 0.9996 1604788 ChemDiv1_026964 COc1ccc(Cl)cc1S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J15 compound treatment 744152.0 287000.0 0.59 700705.0 253000.0 0.55 0.8062 0.9992 1982423 ChemDiv1_026965 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCC(=O)NC4CCCCC4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J16 compound treatment 695023.0 238000.0 0.49 696739.0 249000.0 0.54 0.7285 0.9989 1426419 ChemDiv1_026966 Cc1cc(ccc1F)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J17 compound treatment 727815.0 271000.0 0.56 725789.0 278000.0 0.6 0.8208 0.9993 1982424 ChemDiv1_026967 Cc1cccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J18 compound treatment 770981.0 314000.0 0.65 767334.0 320000.0 0.69 0.9474 0.9995 1982425 ChemDiv1_026968 Cc1ccc(cc1)C2=CC(c3ccc(F)cc3)n4c(N2)nc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J19 compound treatment 719336.0 262000.0 0.54 705144.0 258000.0 0.56 0.7768 0.9999 1982426 ChemDiv1_026969 COc1cccc(NC(=O)/C=C/C(=O)O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J20 compound treatment 822252.0 365000.0 0.75 792378.0 345000.0 0.75 1.0605 1.0 1982427 ChemDiv1_026970 COc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J21 compound treatment 706037.0 249000.0 0.51 732883.0 285000.0 0.62 0.7998 0.9958 1181659 ChemDiv1_026971 COc1ccc(NC(=O)c2c(NCc3ccc(OC)c(OC)c3)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J22 compound treatment 663573.0 206000.0 0.43 678007.0 230000.0 0.5 0.6539 0.9969 1120877 ChemDiv1_026972 CCN1CCN(CC1)C(=O)c2sc3ncn(C)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J23 mock treatment 665518.0 208000.0 0.43 672254.0 225000.0 0.49 0.6479 0.9981 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 J24 mock treatment 226680.0 -231000.0 -0.48 214313.0 -233000.0 -0.5 -0.6935 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K01 compound treatment 635963.0 179000.0 0.37 585845.0 138000.0 0.3 0.4725 0.9946 1982428 ChemDiv1_026973 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4ccccc4C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K02 compound treatment 637670.0 180000.0 0.37 622452.0 175000.0 0.38 0.531 1.0 1982429 ChemDiv1_026974 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K03 compound treatment 666631.0 209000.0 0.43 639461.0 192000.0 0.42 0.5993 0.9998 1982430 ChemDiv1_026975 Cc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(Cl)cc2)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K04 compound treatment 667914.0 211000.0 0.43 662726.0 215000.0 0.47 0.6368 0.9994 1982431 ChemDiv1_026976 Cc1cccc([N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-])c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K05 compound treatment 711959.0 255000.0 0.53 657444.0 210000.0 0.45 0.693 0.9973 1982432 ChemDiv1_026977 Cc1ccccc1N/C(=C(/C#N)\C(=O)N)/SCc2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K06 compound treatment 684771.0 228000.0 0.47 674226.0 227000.0 0.49 0.679 0.9998 1982433 ChemDiv1_026978 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K07 compound treatment 751429.0 294000.0 0.61 658174.0 211000.0 0.46 0.7518 0.99 1982434 ChemDiv1_026979 Cc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3cccc(Br)c3)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K08 compound treatment 697434.0 240000.0 0.5 647927.0 200000.0 0.43 0.6573 0.9978 1982435 ChemDiv1_026980 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K09 compound treatment 727365.0 270000.0 0.56 694918.0 247000.0 0.54 0.7729 0.9998 1982436 ChemDiv1_026981 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccccc2Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K10 compound treatment 703362.0 246000.0 0.51 658219.0 211000.0 0.46 0.6817 0.9985 1982437 ChemDiv1_026982 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K11 compound treatment 738180.0 281000.0 0.58 684188.0 237000.0 0.51 0.7722 0.9981 1982438 ChemDiv1_026983 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K12 compound treatment 714907.0 258000.0 0.53 638365.0 191000.0 0.41 0.6681 0.9922 1982439 ChemDiv1_026984 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K13 compound treatment 731622.0 274000.0 0.57 670139.0 223000.0 0.48 0.7412 0.9967 1982440 ChemDiv1_026985 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K14 compound treatment 739538.0 282000.0 0.58 649938.0 202000.0 0.44 0.7218 0.9901 1982441 ChemDiv1_026986 OC1(C[N+](=C2SCCCN21)c3ccc(Cl)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K15 compound treatment 729923.0 273000.0 0.56 690998.0 243000.0 0.53 0.7706 0.9995 1982442 ChemDiv1_026987 CS/C(=C(\C#N)/C(=O)NCc1cccs1)/Nc2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K16 compound treatment 695690.0 238000.0 0.49 679798.0 232000.0 0.5 0.7035 0.9999 1982443 ChemDiv1_026988 Cc1ccccc1[N+]2=C3SCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K17 compound treatment 729162.0 272000.0 0.56 698651.0 251000.0 0.54 0.7812 0.9999 1982444 ChemDiv1_026989 OC1(C[N+](=C2SCCN21)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K18 compound treatment 698884.0 242000.0 0.5 648450.0 201000.0 0.43 0.6602 0.9976 1982445 ChemDiv1_026990 Cc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K19 compound treatment 802184.0 345000.0 0.71 700503.0 253000.0 0.55 0.8906 0.9916 1982446 ChemDiv1_026991 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K20 compound treatment 685633.0 228000.0 0.47 646062.0 198000.0 0.43 0.6372 0.9989 1982447 ChemDiv1_026992 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K21 compound treatment 698247.0 241000.0 0.5 678712.0 231000.0 0.5 0.7056 1.0 1982448 ChemDiv1_026993 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K22 compound treatment 665513.0 208000.0 0.43 655043.0 207000.0 0.45 0.6216 0.9998 1982449 ChemDiv1_026994 Cc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K23 mock treatment 668871.0 212000.0 0.44 651654.0 204000.0 0.44 0.6213 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 K24 mock treatment 225413.0 -232000.0 -0.48 222502.0 -225000.0 -0.49 -0.6828 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L01 compound treatment 637214.0 180000.0 0.37 601855.0 154000.0 0.33 0.4989 0.9986 1982450 ChemDiv1_026995 Cc1ccc(C)c(c1)[N+]2=C3CCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L02 compound treatment 682939.0 226000.0 0.47 632098.0 185000.0 0.4 0.6119 0.997 1502973 ChemDiv1_026996 CCOC(=O)c1c(NC(=O)c2ccc(F)cc2)sc3CN(CCc13)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L03 compound treatment 690944.0 234000.0 0.48 688656.0 241000.0 0.52 0.7101 0.9992 1982451 ChemDiv1_026997 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L04 compound treatment 690449.0 233000.0 0.48 664514.0 217000.0 0.47 0.6725 0.9999 1339981 ChemDiv1_026998 CCCn1cnc2sc(C(=O)N3CCC(CC3)C(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L05 compound treatment 720830.0 264000.0 0.54 675993.0 228000.0 0.49 0.7344 0.9988 1982452 ChemDiv1_026999 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L06 compound treatment 755867.0 299000.0 0.62 687586.0 240000.0 0.52 0.8033 0.9964 1205922 ChemDiv1_027000 Cc1ccc(c(C)c1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L07 compound treatment 716048.0 259000.0 0.53 720856.0 273000.0 0.59 0.7961 0.9987 1982453 ChemDiv1_027001 COc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L08 compound treatment 703356.0 246000.0 0.51 680756.0 233000.0 0.5 0.7162 1.0 1982454 ChemDiv1_027002 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L09 compound treatment 724389.0 267000.0 0.55 687836.0 240000.0 0.52 0.7577 0.9996 1427712 ChemDiv1_027003 COc1cccc(OC)c1C(=O)Nc2ccc(Oc3ccc(Br)c4ccccc34)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L10 compound treatment 704023.0 247000.0 0.51 654514.0 207000.0 0.45 0.677 0.9979 1982455 ChemDiv1_027004 [O-][N+](=O)c1cccc(c1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L11 compound treatment 723135.0 266000.0 0.55 672672.0 225000.0 0.49 0.7327 0.9982 1320061 ChemDiv1_027005 Clc1ccccc1Cn2cnc3sc4CCCCc4c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L12 compound treatment 713180.0 256000.0 0.53 673347.0 226000.0 0.49 0.7192 0.9992 1574854 ChemDiv1_027006 Cc1ccc(C)c(c1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L13 compound treatment 720120.0 263000.0 0.54 680014.0 232000.0 0.5 0.7395 0.9993 1168230 ChemDiv1_027007 Fc1ccc(Cc2nc3ccccc3nc2SCC(=O)NC4CCCCC4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L14 compound treatment 719523.0 262000.0 0.54 692883.0 245000.0 0.53 0.7583 1.0 1982456 ChemDiv1_027008 Cc1ccc(cc1S(=O)(=O)N(CC2CCCO2)Cc3ccco3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L15 compound treatment 715252.0 258000.0 0.53 755636.0 308000.0 0.67 0.8481 0.9938 1982457 ChemDiv1_027009 CCCCNC(=O)CSc1nc2ccccc2nc1Cc3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L16 compound treatment 718457.0 261000.0 0.54 701296.0 254000.0 0.55 0.7696 1.0 1178587 ChemDiv1_027010 Cc1ccc(cc1)C2CC(c3cccs3)n4ncnc4N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L17 compound treatment 726237.0 269000.0 0.56 691622.0 244000.0 0.53 0.7662 0.9997 1982458 ChemDiv1_027011 COC(=O)CSc1nc2ccccc2nc1Cc3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L18 compound treatment 818521.0 361000.0 0.75 857480.0 410000.0 0.89 1.1547 0.9963 1982459 ChemDiv1_027012 COc1ccc(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L19 compound treatment 712274.0 255000.0 0.53 716579.0 269000.0 0.58 0.784 0.9987 1982460 ChemDiv1_027013 COc1ccc(C)cc1NC(=O)/C=C/C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L20 compound treatment 728997.0 272000.0 0.56 749422.0 302000.0 0.65 0.8587 0.9971 1982461 ChemDiv1_027014 Fc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L21 compound treatment 704749.0 248000.0 0.51 727245.0 280000.0 0.61 0.7893 0.9965 1205092 ChemDiv1_027015 COc1ccc(NC(=O)c2c(NCc3ccc(OC)c(OC)c3OC)sc4CCCCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L22 compound treatment 666157.0 209000.0 0.43 669535.0 222000.0 0.48 0.6447 0.9986 1394216 ChemDiv1_027016 CCn1cnc2sc(C(=O)N3CCC(CC3)C(=O)N)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L23 mock treatment 653486.0 196000.0 0.41 665367.0 218000.0 0.47 0.6198 0.9972 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 L24 mock treatment 224062.0 -233000.0 -0.48 225025.0 -223000.0 -0.48 -0.6809 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M01 compound treatment 645621.0 188000.0 0.39 581229.0 134000.0 0.29 0.4796 0.9894 1982462 ChemDiv1_027017 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4cccc(F)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M02 compound treatment 692649.0 235000.0 0.49 621983.0 174000.0 0.38 0.6106 0.9922 1982463 ChemDiv1_027018 COc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M03 compound treatment 697934.0 241000.0 0.5 641335.0 194000.0 0.42 0.6479 0.9964 1982464 ChemDiv1_027019 Cc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(c2)[N+](=O)[O-])cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M04 compound treatment 686231.0 229000.0 0.47 621110.0 174000.0 0.38 0.5999 0.9935 1982465 ChemDiv1_027020 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M05 compound treatment 835651.0 378000.0 0.78 625485.0 178000.0 0.39 0.8247 0.9469 1982466 ChemDiv1_027021 Cc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(Br)c2)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M06 compound treatment 688243.0 231000.0 0.48 632483.0 185000.0 0.4 0.6202 0.9962 1982467 ChemDiv1_027022 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M07 compound treatment 724422.0 267000.0 0.55 666415.0 219000.0 0.47 0.725 0.9971 1982468 ChemDiv1_027023 CCOc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M08 compound treatment 691651.0 234000.0 0.48 676519.0 229000.0 0.5 0.6926 0.9999 1982469 ChemDiv1_027024 COc1ccc(OC)c(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M09 compound treatment 727305.0 270000.0 0.56 653822.0 206000.0 0.45 0.7099 0.9939 1982470 ChemDiv1_027025 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(c2)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M10 compound treatment 712369.0 255000.0 0.53 611876.0 164000.0 0.36 0.6239 0.9817 1982471 ChemDiv1_027026 COc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M11 compound treatment 726686.0 269000.0 0.56 659605.0 212000.0 0.46 0.7178 0.9954 1982472 ChemDiv1_027027 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M12 compound treatment 703146.0 246000.0 0.51 614830.0 167000.0 0.36 0.6149 0.9862 1982473 ChemDiv1_027028 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M13 compound treatment 702153.0 245000.0 0.51 633163.0 186000.0 0.4 0.6416 0.9935 1982474 ChemDiv1_027029 CCOc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccc(C)cc2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M14 compound treatment 712864.0 256000.0 0.53 669043.0 221000.0 0.48 0.7121 0.9988 1982475 ChemDiv1_027030 CCOc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M15 compound treatment 749836.0 293000.0 0.6 672878.0 225000.0 0.49 0.7719 0.9944 1982476 ChemDiv1_027031 Cc1ccccc1CS/C(=C(\C#N)/C(=O)NCc2cccs2)/Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M16 compound treatment 695143.0 238000.0 0.49 609329.0 162000.0 0.35 0.5948 0.9862 1982477 ChemDiv1_027032 Cc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M17 compound treatment 707439.0 250000.0 0.52 673145.0 226000.0 0.49 0.7105 0.9996 1982478 ChemDiv1_027033 OC1(C[N+](=C2SCCN21)c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M18 compound treatment 669763.0 213000.0 0.44 666603.0 219000.0 0.47 0.6455 0.9993 1982479 ChemDiv1_027034 Cc1ccc(c(C)c1)C2(O)C[N+](=C3SCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M19 compound treatment 721584.0 264000.0 0.55 743710.0 296000.0 0.64 0.8391 0.9968 1982480 ChemDiv1_027035 Cc1ccc(c(C)c1)C2(O)C[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M20 compound treatment 674887.0 218000.0 0.45 639063.0 191000.0 0.41 0.6108 0.9992 1982481 ChemDiv1_027036 Cc1cccc(c1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M21 compound treatment 678942.0 222000.0 0.46 692142.0 245000.0 0.53 0.6979 0.9974 1982482 ChemDiv1_027037 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M22 compound treatment 656862.0 200000.0 0.41 666976.0 219000.0 0.47 0.6272 0.9975 1982483 ChemDiv1_027038 COc1ccc(cc1OC)C2(O)C[N+](=C3CCCCN32)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M23 mock treatment 640560.0 183000.0 0.38 652695.0 205000.0 0.44 0.5815 0.9969 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 M24 mock treatment 395525.0 -61700.0 -0.13 361775.0 -85800.0 -0.19 -0.2214 -0.983 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N01 compound treatment 691157.0 234000.0 0.48 633458.0 186000.0 0.4 0.626 0.9959 1982484 ChemDiv1_027039 CCOc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N02 compound treatment 666681.0 209000.0 0.43 680464.0 233000.0 0.5 0.6622 0.9971 1557250 ChemDiv1_027040 Cc1cc2NC(=O)CC(c3cc(Br)ccc3F)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N03 compound treatment 688626.0 231000.0 0.48 675454.0 228000.0 0.49 0.6865 0.9999 1982485 ChemDiv1_027041 CCOc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N04 compound treatment 677397.0 220000.0 0.45 646187.0 199000.0 0.43 0.6254 0.9996 1174099 ChemDiv1_027042 CCCn1cnc2sc(C(=O)N3C(C)CCc4cc(F)ccc34)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N05 compound treatment 693684.0 236000.0 0.49 700502.0 253000.0 0.55 0.7323 0.9984 1982486 ChemDiv1_027043 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(OCC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N06 compound treatment 670605.0 213000.0 0.44 659280.0 212000.0 0.46 0.6355 0.9998 1630723 ChemDiv1_027044 COc1cccc(c1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N07 compound treatment 700217.0 243000.0 0.5 717939.0 270000.0 0.59 0.7685 0.9971 1982487 ChemDiv1_027045 Cc1ccccc1[N+]2=C3CCCCN3C(O)(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N08 compound treatment 688405.0 231000.0 0.48 662085.0 214000.0 0.46 0.6658 0.9999 1460350 ChemDiv1_027046 Fc1ccc(cc1F)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N09 compound treatment 705057.0 248000.0 0.51 679539.0 232000.0 0.5 0.7168 1.0 1139934 ChemDiv1_027047 Fc1cccc(F)c1C(=O)Nc2ccc(Oc3ccc(Br)c4ccccc34)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N10 compound treatment 700980.0 244000.0 0.5 655541.0 208000.0 0.45 0.6741 0.9984 1982488 ChemDiv1_027048 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N11 compound treatment 700990.0 244000.0 0.5 642582.0 195000.0 0.42 0.6543 0.9962 1982489 ChemDiv1_027049 FC(F)(F)c1ccc(Cn2cnc3sc4CCCCc4c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N12 compound treatment 662767.0 206000.0 0.42 639927.0 192000.0 0.42 0.5944 1.0 1542337 ChemDiv1_027050 Cc1cc(ccc1F)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N13 compound treatment 694509.0 237000.0 0.49 654363.0 207000.0 0.45 0.6628 0.999 1982490 ChemDiv1_027051 CCCCNC(=O)CSc1nc2ccccc2nc1Cc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N14 compound treatment 688798.0 232000.0 0.48 681612.0 234000.0 0.51 0.6962 0.9996 1982491 ChemDiv1_027052 [O-][N+](=O)c1cccc(c1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N15 compound treatment 717864.0 261000.0 0.54 685018.0 237000.0 0.51 0.7439 0.9997 1982492 ChemDiv1_027053 CN(C)c1ccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N16 compound treatment 672366.0 215000.0 0.44 679438.0 232000.0 0.5 0.6689 0.9981 1684078 ChemDiv1_027054 CSc1ccc(cc1)C2CC(Nc3ncnn23)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N17 compound treatment 685237.0 228000.0 0.47 745589.0 298000.0 0.64 0.7889 0.988 1982493 ChemDiv1_027055 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc4cccc(c4)[N+](=O)[O-])c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N18 compound treatment 798527.0 341000.0 0.7 835014.0 387000.0 0.84 1.0912 0.9963 1354173 ChemDiv1_027056 COc1cc(OC)c(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N19 compound treatment 691111.0 234000.0 0.48 704629.0 257000.0 0.56 0.7348 0.9975 1982494 ChemDiv1_027057 COc1ccc(OC)c(NC(=O)/C=C/C(=O)O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N20 compound treatment 695239.0 238000.0 0.49 756868.0 309000.0 0.67 0.8208 0.9884 1982495 ChemDiv1_027058 Cc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N21 compound treatment 673366.0 216000.0 0.45 741915.0 294000.0 0.64 0.766 0.9848 1197899 ChemDiv1_027059 CCOc1ccccc1NC(=O)c2c(NCc3ccncc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N22 compound treatment 655519.0 198000.0 0.41 690810.0 243000.0 0.53 0.6617 0.9923 1430253 ChemDiv1_027060 CCN1CCN(CC1)C(=O)c2sc3ncn(CC)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N23 mock treatment 616306.0 159000.0 0.33 650206.0 203000.0 0.44 0.5423 0.9899 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 N24 mock treatment 379420.0 -77800.0 -0.16 372540.0 -75100.0 -0.16 -0.2284 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O01 compound treatment 614165.0 157000.0 0.32 563915.0 116000.0 0.25 0.4071 0.9922 1982496 ChemDiv1_027061 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccc3OCOc3c2)/SCc4ccc(C)cc4C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O02 compound treatment 660974.0 204000.0 0.42 595467.0 148000.0 0.32 0.5238 0.9909 1982497 ChemDiv1_027062 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4ccccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O03 compound treatment 691077.0 234000.0 0.48 691393.0 244000.0 0.53 0.7145 0.999 1982498 ChemDiv1_027063 CCOc1ccc(N/C(=C(/C#N)\C(=O)N)/SC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O04 compound treatment 664671.0 207000.0 0.43 615128.0 168000.0 0.36 0.5592 0.9966 1982499 ChemDiv1_027064 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O05 compound treatment 674995.0 218000.0 0.45 599451.0 152000.0 0.33 0.5503 0.9881 1982500 ChemDiv1_027065 CCOc1ccc(N/C(=C(/C#N)\C(=O)NCc2ccco2)/SCc3ccccc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O06 compound treatment 650022.0 193000.0 0.4 612578.0 165000.0 0.36 0.534 0.9985 1982501 ChemDiv1_027066 CCc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4cc(OC)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O07 compound treatment 667844.0 211000.0 0.43 611193.0 164000.0 0.35 0.5579 0.9948 1982502 ChemDiv1_027067 CCc1ccc(N/C(=C(/C#N)\C(=O)N)/SCc2ccccc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O08 compound treatment 685997.0 229000.0 0.47 613388.0 166000.0 0.36 0.5877 0.9908 1982503 ChemDiv1_027068 COc1ccc(c(F)c1)C2(O)C[N+](=C3SCCCN32)c4cc(OC)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O09 compound treatment 702342.0 245000.0 0.51 628124.0 181000.0 0.39 0.6341 0.9918 1982504 ChemDiv1_027069 COc1cccc(N/C(=C(/C#N)\C(=O)N)/SCc2cccc(F)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O10 compound treatment 667428.0 210000.0 0.43 648445.0 201000.0 0.43 0.6143 1.0 1982505 ChemDiv1_027070 CCc1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O11 compound treatment 694338.0 237000.0 0.49 642573.0 195000.0 0.42 0.6446 0.9973 1982506 ChemDiv1_027071 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O12 compound treatment 634050.0 177000.0 0.37 581829.0 134000.0 0.29 0.4636 0.9936 1982507 ChemDiv1_027072 CCOc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O13 compound treatment 660879.0 204000.0 0.42 636161.0 189000.0 0.41 0.5859 0.9999 1982508 ChemDiv1_027073 CCOc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O14 compound treatment 663464.0 206000.0 0.43 620275.0 173000.0 0.37 0.5654 0.9979 1982509 ChemDiv1_027074 OC1(C[N+](=C2SCCCN21)c3ccc(Cl)cc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O15 compound treatment 696926.0 240000.0 0.49 656964.0 209000.0 0.45 0.6704 0.999 1982510 ChemDiv1_027075 Cc1ccccc1N/C(=C(/C#N)\C(=O)NCc2cccs2)/SCc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O16 compound treatment 661504.0 204000.0 0.42 637944.0 190000.0 0.41 0.5895 0.9999 1982511 ChemDiv1_027076 Cc1ccccc1[N+]2=C3SCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O17 compound treatment 677117.0 220000.0 0.45 655358.0 208000.0 0.45 0.639 1.0 1982512 ChemDiv1_027077 OC1(C[N+](=C2SCCN21)c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O18 compound treatment 680713.0 224000.0 0.46 646083.0 198000.0 0.43 0.63 0.9994 1982513 ChemDiv1_027078 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O19 compound treatment 705506.0 248000.0 0.51 662981.0 215000.0 0.47 0.6921 0.9989 1982514 ChemDiv1_027079 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O20 compound treatment 643121.0 186000.0 0.38 640364.0 193000.0 0.42 0.5664 0.9991 1982515 ChemDiv1_027080 COc1ccc(cc1OC)C2(O)C[N+](=C3SCCCN32)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O21 compound treatment 664752.0 208000.0 0.43 666940.0 219000.0 0.47 0.6387 0.9987 1982516 ChemDiv1_027081 Cc1ccc(cc1)[N+]2=C3SCCCN3C(O)(C2)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O22 compound treatment 627115.0 170000.0 0.35 607702.0 160000.0 0.35 0.4931 1.0 1982517 ChemDiv1_027082 Cc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4cccc(C)c4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O23 mock treatment 617861.0 161000.0 0.33 624539.0 177000.0 0.38 0.5053 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 O24 mock treatment 326810.0 -130000.0 -0.27 414437.0 -33200.0 -0.07 -0.2411 -0.8654 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P01 compound treatment 624280.0 167000.0 0.34 554605.0 107000.0 0.23 0.4077 0.9812 1982518 ChemDiv1_027083 COc1ccc(cc1OC)C2(O)C[N+](=C3CCCCN32)c4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P02 compound treatment 627441.0 170000.0 0.35 589117.0 142000.0 0.31 0.4651 0.9977 1117850 ChemDiv1_027084 CCOC(=O)C1CCN(CC1)C(=O)c2sc3ncn(CC)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P03 compound treatment 633529.0 176000.0 0.36 592655.0 145000.0 0.31 0.4794 0.9973 1982519 ChemDiv1_027085 COc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P04 compound treatment 634117.0 177000.0 0.37 590750.0 143000.0 0.31 0.4773 0.9967 1514650 ChemDiv1_027086 CCCn1cnc2sc(C(=O)N3CCC(Cc4ccccc4)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P05 compound treatment 636189.0 179000.0 0.37 600223.0 153000.0 0.33 0.4949 0.9984 1982520 ChemDiv1_027087 CCOc1ccc(cc1)[N+]2=C3CCCCN3C(O)(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P06 compound treatment 650789.0 194000.0 0.4 608768.0 161000.0 0.35 0.5292 0.9977 1982521 ChemDiv1_027088 C=CCSc1nnc(c2ccncc2)n1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P07 compound treatment 632707.0 176000.0 0.36 589041.0 141000.0 0.31 0.4727 0.9965 1982522 ChemDiv1_027089 CCOc1ccc(cc1)C2(O)C[N+](=C3CCCCN32)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P08 compound treatment 632330.0 175000.0 0.36 603088.0 155000.0 0.34 0.4936 0.9994 1679105 ChemDiv1_027090 O=C1N(CC2N(CCc3ccccc23)S(=O)(=O)Cc4ccccc4)C(=O)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P09 compound treatment 629997.0 173000.0 0.36 602523.0 155000.0 0.34 0.4893 0.9995 1640075 ChemDiv1_027091 COc1cccc2C=CC3(Oc12)N(C)c4ccccc4-c5ccccc53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P10 compound treatment 644603.0 187000.0 0.39 603043.0 155000.0 0.34 0.5115 0.9976 1226616 ChemDiv1_027092 Clc1ccc(s1)S(=O)(=O)N2CCc3ccccc3C2CN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P11 compound treatment 602569.0 145000.0 0.3 608996.0 161000.0 0.35 0.4592 0.9971 1982523 ChemDiv1_027093 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccccc4[N+](=O)[O-])/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P12 compound treatment 613407.0 156000.0 0.32 584468.0 137000.0 0.3 0.4375 0.9991 1982524 ChemDiv1_027094 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P13 compound treatment 618843.0 162000.0 0.33 594301.0 147000.0 0.32 0.4605 0.9997 1513071 ChemDiv1_027095 CC(C)(C)C(=O)CSc1nc2ccccc2nc1Cc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P14 compound treatment 650530.0 193000.0 0.4 597503.0 150000.0 0.32 0.5116 0.9947 1982525 ChemDiv1_027096 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N(CC2CCCO2)Cc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P15 compound treatment 625855.0 169000.0 0.35 601330.0 154000.0 0.33 0.4815 0.9997 1982526 ChemDiv1_027097 CC(C)(C)C(=O)CSc1nc2ccccc2nc1Cc3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P16 compound treatment 669451.0 212000.0 0.44 624801.0 177000.0 0.38 0.581 0.9978 1308093 ChemDiv1_027098 Cc1ccsc1C2CC(Nc3ncnn23)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P17 compound treatment 636946.0 180000.0 0.37 629673.0 182000.0 0.39 0.541 0.9995 1982527 ChemDiv1_027099 [O-][N+](=O)c1cccc(Cc2nc3ccccc3nc2SCC(=O)Nc4ccc(F)c(Cl)c4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P18 compound treatment 775934.0 319000.0 0.66 743549.0 296000.0 0.64 0.9182 0.9999 1982528 ChemDiv1_027100 COc1ccc(cc1OC)C2C=C(Nc3nc4ccccc4n23)c5cccc(Br)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P19 compound treatment 645794.0 189000.0 0.39 626944.0 179000.0 0.39 0.5498 1.0 1982529 ChemDiv1_027101 COc1cc(NC(=O)/C=C/C(=O)O)cc(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P20 compound treatment 626212.0 169000.0 0.35 618534.0 171000.0 0.37 0.5083 0.9996 1982530 ChemDiv1_027102 Cc1c(sc2ncn(C)c(=O)c12)C(=O)N3CCC(CC3)(N4CCCCC4)C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P21 compound treatment 618253.0 161000.0 0.33 588736.0 141000.0 0.31 0.4511 0.9991 1537404 ChemDiv1_027103 CCOc1ccccc1NC(=O)c2c(NCc3ccc(OC)c(OC)c3OC)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P22 compound treatment 615253.0 158000.0 0.33 614470.0 167000.0 0.36 0.4861 0.9987 1228615 ChemDiv1_027104 CCCn1cnc2sc(C(=O)N3CCN(CC3)C(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P23 mock treatment 585429.0 128000.0 0.26 592608.0 145000.0 0.31 0.4091 0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.663 P24 mock treatment 423422.0 -33800.0 -0.07 457894.0 10300.0 0.02 -0.0335 -0.4582 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A01 compound treatment 656736.0 185000.0 0.38 597129.0 112000.0 0.24 0.4426 0.9761 1239638 ChemDiv1_027105 CCCn1cnc2sc(C(=O)N3CCC4(CC3)OCCO4)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A02 compound treatment 677103.0 206000.0 0.42 642116.0 157000.0 0.34 0.5411 0.994 1982531 ChemDiv1_027106 COc1ccc(cc1)[C@@H]2[C@@H]([n+]3cccc4cc(Cl)ccc34)[C@@](O)(NC(=C2C#N)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A03 compound treatment 625327.0 154000.0 0.32 588233.0 103000.0 0.22 0.3831 0.9853 1982532 ChemDiv1_027107 COc1ccc(c(F)c1)C2(O)C(C)[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A04 compound treatment 632056.0 161000.0 0.33 575936.0 91200.0 0.2 0.3741 0.9692 1119085 ChemDiv1_027108 CC1OC(Sc2ccccn2)C(OC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A05 compound treatment 648580.0 177000.0 0.37 607710.0 123000.0 0.27 0.4469 0.9878 1982533 ChemDiv1_027109 CCOCCn1cnc2sc(C(=O)NC3CCCC(C)C3C)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A06 compound treatment 662516.0 191000.0 0.39 617584.0 133000.0 0.29 0.4823 0.9879 1982534 ChemDiv1_027110 NC(=O)[C@H]1[C@H](c2ccc(F)c(Br)c2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A07 compound treatment 660124.0 189000.0 0.39 629554.0 145000.0 0.31 0.4971 0.9942 1982535 ChemDiv1_027111 CCOCCn1cnc2sc(C(=O)NCC(OCC)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A08 compound treatment 659551.0 188000.0 0.39 616539.0 132000.0 0.29 0.4764 0.9885 1174106 ChemDiv1_027112 CN(C)Cc1c(O)ccc2oc3CCCC(=O)c3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A09 compound treatment 660440.0 189000.0 0.39 618332.0 134000.0 0.29 0.4804 0.9891 1982536 ChemDiv1_027113 CCOCCn1cnc2sc(C(=O)NCCN3CCOCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A10 compound treatment 667364.0 196000.0 0.4 627931.0 143000.0 0.31 0.5052 0.9913 1549383 ChemDiv1_027114 Cc1ccc(cc1)N2CCN(C2c3ccc(Cl)cc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A11 compound treatment 658642.0 187000.0 0.39 623812.0 139000.0 0.3 0.4862 0.9923 1594843 ChemDiv1_027115 COCCn1cnc2sc(C(=O)N3CCC(C)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A12 compound treatment 675161.0 204000.0 0.42 647749.0 163000.0 0.35 0.5469 0.9962 1982537 ChemDiv1_027116 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4cc(c(O)c(c4)C(C)(C)C)C(C)(C)C)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A13 compound treatment 671169.0 200000.0 0.41 632064.0 147000.0 0.32 0.5171 0.9919 1021486 ChemDiv1_027117 Cc1ccc(O)c(CN2CCCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A14 compound treatment 694703.0 223000.0 0.46 633239.0 148000.0 0.32 0.5533 0.9844 1982538 ChemDiv1_027118 C/C(=N\NC(=O)C1C(C(C1c2ccccc2)C(=O)N3CCOCC3)c4ccccc4)/c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A15 compound treatment 670219.0 199000.0 0.41 645971.0 161000.0 0.35 0.537 0.9967 1555697 ChemDiv1_027119 COC(=O)Nc1ccc2CCc3ccccc3Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A16 compound treatment 1133921.0 663000.0 1.37 1118167.0 633000.0 1.37 1.9365 1.0 1982539 ChemDiv1_027120 CC(=O)[C@@H]1[C@H]2C3COC(O3)C(=O)[C@@H]2[C@H]4C=Cc5ccccc5N14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A17 compound treatment 696659.0 225000.0 0.47 627809.0 143000.0 0.31 0.5478 0.9805 1982540 ChemDiv1_027121 CCN(CC)CC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CN(CC)CC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A18 compound treatment 653844.0 182000.0 0.38 644823.0 160000.0 0.35 0.5113 0.9991 1374073 ChemDiv1_027122 CCOC(=O)C1C(C(=O)OCC)C2(CCCCC2)OC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A19 compound treatment 649244.0 178000.0 0.37 636311.0 152000.0 0.33 0.4916 0.9984 1982541 ChemDiv1_027123 CC1=NN(C(=O)C1C(C2C(=NN(C2=O)c3ccc(C)cc3)C)c4ccccc4)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A20 compound treatment 638754.0 167000.0 0.35 618963.0 134000.0 0.29 0.4497 0.9963 1929928 ChemDiv1_027124 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4c(Cl)cccc4Cl)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A21 compound treatment 632661.0 161000.0 0.33 616054.0 131000.0 0.28 0.4364 0.9969 1982542 ChemDiv1_027125 Cc1cccc[n+]1C2C(C(=C(NC2(O)C3CC3)[C-](C#N)C#N)C#N)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A22 compound treatment 626045.0 155000.0 0.32 624595.0 140000.0 0.3 0.4398 0.9996 1982543 ChemDiv1_027126 NC(=O)[C@H]1[C@H](c2ccccc2F)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A23 mock treatment 595335.0 124000.0 0.26 595747.0 111000.0 0.24 0.3508 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 A24 mock treatment 181097.0 -290000.0 -0.6 229978.0 -255000.0 -0.55 -0.8136 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B01 compound treatment 736772.0 265000.0 0.55 645786.0 161000.0 0.35 0.6339 0.9762 1982544 ChemDiv1_027127 CC(=O)[C@@H]1[C@@H](c2ccc(Cl)cc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B02 compound treatment 675634.0 204000.0 0.42 626110.0 141000.0 0.31 0.5145 0.9876 1982545 ChemDiv1_027128 CCOC(=O)[C@@H]1[C@H](C(=C(N[C@]1(C)O)SCC(=O)NC2CC2)C#N)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B03 compound treatment 715968.0 245000.0 0.5 665417.0 181000.0 0.39 0.6335 0.992 1479813 ChemDiv1_027129 Cc1cc2Cc3cc4ccccc4nc3-c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B04 compound treatment 752478.0 281000.0 0.58 661159.0 176000.0 0.38 0.6803 0.9794 1783894 ChemDiv1_027130 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B05 compound treatment 737228.0 266000.0 0.55 678951.0 194000.0 0.42 0.6853 0.9913 1982546 ChemDiv1_027131 Cc1ccc-2c(c1)/C(=C/c3ccccc3)/c4cc5ccccc5nc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B06 compound treatment 723375.0 252000.0 0.52 673497.0 189000.0 0.41 0.6567 0.9928 1982547 ChemDiv1_027132 CCCCNC(=O)N(O)C1N(CCN2CCOCC2)C(=S)SC1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B07 compound treatment 760129.0 289000.0 0.6 730647.0 246000.0 0.53 0.7978 0.9984 1982548 ChemDiv1_027133 Cc1nnc(SCc2nc(oc2CSc3nnc(C)c(=O)[nH]3)c4ccccc4)[nH]c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B08 compound treatment 727734.0 256000.0 0.53 692768.0 208000.0 0.45 0.6926 0.9968 1387435 ChemDiv1_027134 CCOC(=O)c1nnn(c1CN(CC)CC)c2nonc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B09 compound treatment 793602.0 322000.0 0.67 710361.0 226000.0 0.49 0.8156 0.9884 1982549 ChemDiv1_027135 O=C(O/N=C/1\CCCc2c1sc3nc4CCCCCn4c(=O)c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B10 compound treatment 724710.0 253000.0 0.52 686695.0 202000.0 0.44 0.6789 0.996 1288159 ChemDiv1_027136 Cc1cccc(NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B11 compound treatment 732566.0 261000.0 0.54 703064.0 218000.0 0.47 0.7154 0.9978 1982550 ChemDiv1_027137 CCOC(=O)C1(C)C=C(Nc2ccc(O)cc2)C(=O)N1c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B12 compound treatment 817176.0 346000.0 0.71 776396.0 292000.0 0.63 0.9511 0.9981 1982551 ChemDiv1_027138 CC(C)(C)C(=O)[C@H]1[C@H](c2ccccc2F)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B13 compound treatment 734719.0 263000.0 0.54 708494.0 224000.0 0.48 0.7268 0.9983 1652227 ChemDiv1_027139 CC1(C)Cc2ccccc2C3=C(C(=O)N4CCCC4)C(O)(CC=C)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B14 compound treatment 738611.0 267000.0 0.55 681199.0 196000.0 0.43 0.6907 0.9917 1982552 ChemDiv1_027140 CN(C(=O)C)C1(CCCCC1)c2nnnn2c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B15 compound treatment 751400.0 280000.0 0.58 716054.0 231000.0 0.5 0.7628 0.9974 1982553 ChemDiv1_027141 [O-][N+](=O)c1ncn(n1)[C@@H]2[C@H](CC(=CC2=O)c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B16 compound treatment 712422.0 241000.0 0.5 710115.0 225000.0 0.49 0.6968 1.0 1982554 ChemDiv1_027142 CCCS(=O)(=O)c1c(C(=O)N/N=C\c2c[nH]c3ccccc23)n4cccc(C)c4c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B17 compound treatment 751142.0 280000.0 0.58 745940.0 261000.0 0.57 0.8081 0.9999 1982555 ChemDiv1_027143 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B18 compound treatment 721136.0 250000.0 0.52 698874.0 214000.0 0.46 0.6923 0.9986 1982556 ChemDiv1_027144 Brc1ccc(CSc2nnc(c3ccco3)n2c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B19 compound treatment 846246.0 375000.0 0.77 795768.0 311000.0 0.67 1.0232 0.9976 1982557 ChemDiv1_027145 Fc1ccc2N3[C@@H]([C@@H](c4ccccc4Cl)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B20 compound treatment 726505.0 255000.0 0.53 710382.0 226000.0 0.49 0.7177 0.9993 1982558 ChemDiv1_027146 O=C1C2C(C3C(=O)CC2c4ccccc34)C(=O)N1Cc5cccnc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B21 compound treatment 1903822.0 1430000.0 2.96 1994763.0 1510000.0 3.27 4.4019 0.9988 1982559 ChemDiv1_027147 CC(C)(C)C(=O)[C@@H]1[C@@H](c2cccs2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B22 compound treatment 688680.0 217000.0 0.45 671235.0 186000.0 0.4 0.6026 0.9986 1982560 ChemDiv1_027148 Cc1c(CSc2nnc(c3ccco3)n2c4ccccc4)cccc1c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B23 mock treatment 731778.0 260000.0 0.54 759531.0 275000.0 0.59 0.8007 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 B24 mock treatment 218617.0 -253000.0 -0.52 229392.0 -255000.0 -0.55 -0.7597 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C01 compound treatment 710838.0 239000.0 0.49 669502.0 185000.0 0.4 0.6323 0.9945 1317907 ChemDiv1_027149 CCCn1cnc2sc(C(=O)N3CC(C)CC(C)C3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C02 compound treatment 1149959.0 679000.0 1.4 1353758.0 869000.0 1.88 2.3205 0.9895 1982561 ChemDiv1_027150 COc1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C03 compound treatment 712743.0 241000.0 0.5 711502.0 227000.0 0.49 0.6994 1.0 1704871 ChemDiv1_027151 Cn1c(=O)n(C)c2nc3SCC(=O)n3c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C04 compound treatment 760195.0 289000.0 0.6 780067.0 295000.0 0.64 0.8736 0.9994 1982562 ChemDiv1_027152 OC1=C(C#N)[C@@H]([C@@H]([n+]2cccc3ccccc23)[C@@](O)(N1)c4ccccc4)c5cccc(I)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C05 compound treatment 727964.0 257000.0 0.53 695665.0 211000.0 0.46 0.6973 0.9973 1982563 ChemDiv1_027153 CCOCCn1cnc2sc(C(=O)N3CCCc4ccccc34)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C06 compound treatment 698646.0 227000.0 0.47 666594.0 182000.0 0.39 0.6101 0.9962 1982564 ChemDiv1_027154 CN1CC2(C)OC(=O)C(=C2CC1c3ccccc3)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C07 compound treatment 737413.0 266000.0 0.55 725245.0 240000.0 0.52 0.7564 0.9996 1982565 ChemDiv1_027155 CCOCCn1cnc2sc(C(=O)N3CCN(CC3)C(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C08 compound treatment 734417.0 263000.0 0.54 716426.0 232000.0 0.5 0.7385 0.9992 1156457 ChemDiv1_027156 CCS(=O)(=O)c1c(C(=O)c2ccc(Cl)cc2)n3ccc4ccccc4c3c1S(=O)(=O)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C09 compound treatment 761286.0 290000.0 0.6 727326.0 243000.0 0.53 0.7944 0.9979 1982566 ChemDiv1_027157 CCCCNC(=O)c1sc2ncn(CCOCC)c(=O)c2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C10 compound treatment 736238.0 265000.0 0.55 700818.0 216000.0 0.47 0.7173 0.997 1982567 ChemDiv1_027158 C(N1CCCCC1)C2=Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C11 compound treatment 750238.0 279000.0 0.58 720867.0 236000.0 0.51 0.7684 0.9982 1982568 ChemDiv1_027159 FC(F)(F)c1cccc(c1)C(=O)Nc2ccc3c(c2)-c4cc(NC(=O)c5cccc(c5)C(F)(F)F)ccc4S3(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C12 compound treatment 734450.0 263000.0 0.54 705681.0 221000.0 0.48 0.7221 0.998 1982569 ChemDiv1_027160 Oc1cccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C13 compound treatment 762405.0 291000.0 0.6 738090.0 253000.0 0.55 0.8125 0.999 1982570 ChemDiv1_027161 CC1(C2C(C(=O)O)C3(CC(=C)C4(O)C3)C(CC4)C52OC1=O)C(O)C=C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C14 compound treatment 732905.0 262000.0 0.54 715522.0 231000.0 0.5 0.7349 0.9992 1982571 ChemDiv1_027162 CSC1=N/C(=N\c2cccc(c2)C(F)(F)F)/C3(CCCCC3)N1c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C15 compound treatment 735805.0 264000.0 0.55 714913.0 230000.0 0.5 0.7382 0.999 1236632 ChemDiv1_027163 CCOC(=O)Nc1ccc2CCc3ccccc3Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C16 compound treatment 775310.0 304000.0 0.63 764374.0 280000.0 0.61 0.8716 0.9998 1982572 ChemDiv1_027164 COc1cccc(/C=C\2/SC(=NC2=O)N3CCN(CC3)C4=NC(=O)/C(=C\c5cccc(OC)c5)/S4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C17 compound treatment 783487.0 312000.0 0.64 773434.0 289000.0 0.62 0.8974 0.9999 1931302 ChemDiv1_027165 CN(C)CC(=O)N1c2ccccc2CCc3ccc(NC(=O)N)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C18 compound treatment 714923.0 244000.0 0.5 686661.0 202000.0 0.44 0.6645 0.9976 1982573 ChemDiv1_027166 C[C@@]12CCC3C(=CCC4=CC(=O)CC[C@]34C)C2CC[C@]1(O)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C19 compound treatment 722129.0 251000.0 0.52 711215.0 226000.0 0.49 0.7126 0.9996 1982574 ChemDiv1_027167 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4cccc([N+](=O)[O-])c4O)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C20 compound treatment 713617.0 242000.0 0.5 703879.0 219000.0 0.47 0.689 0.9996 1982575 ChemDiv1_027168 CC(C)(C)N1C(=O)C2C(C3C(=O)CC2c4ccccc34)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C21 compound treatment 761660.0 290000.0 0.6 747541.0 263000.0 0.57 0.8259 0.9997 1982576 ChemDiv1_027169 COc1ccccc1C2C([n+]3ccc(C)cc3)C(O)(NC(=C2C#N)[C-](C#N)C#N)C4CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C22 compound treatment 680474.0 209000.0 0.43 701276.0 217000.0 0.47 0.6366 0.9992 1781407 ChemDiv1_027170 O=C(Nc1cc2C3CCCC3CN4CC5CCCC5c(c1)c42)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C23 mock treatment 674302.0 203000.0 0.42 673972.0 189000.0 0.41 0.5858 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 C24 mock treatment 220376.0 -251000.0 -0.52 244094.0 -241000.0 -0.52 -0.7347 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D01 compound treatment 779619.0 308000.0 0.64 670461.0 186000.0 0.4 0.7342 0.9755 1982577 ChemDiv1_027171 CC(=O)[C@@H]1[C@@H](c2ccc(Br)cc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D02 compound treatment 690557.0 219000.0 0.45 667714.0 183000.0 0.4 0.6 0.9978 1982578 ChemDiv1_027172 [O-][N+](=O)c1ncn(n1)[C@@H]2[C@H](CC(=CC2=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D03 compound treatment 694089.0 223000.0 0.46 672160.0 187000.0 0.41 0.6119 0.998 1067287 ChemDiv1_027173 C1c2ccccc2-c3nc4ccccc4cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D04 compound treatment 708156.0 237000.0 0.49 666354.0 182000.0 0.39 0.6236 0.9942 1982579 ChemDiv1_027174 Clc1ccc(cc1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D05 compound treatment 740264.0 269000.0 0.56 685179.0 200000.0 0.43 0.6993 0.9926 1524517 ChemDiv1_027175 Cc1ccc2C(=O)c3cc4ccccc4nc3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D06 compound treatment 726965.0 256000.0 0.53 665546.0 181000.0 0.39 0.6498 0.9892 1703239 ChemDiv1_027176 CC1(C)SC(=S)N(CCN2CCOCC2)C1N(O)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D07 compound treatment 749736.0 278000.0 0.57 683292.0 199000.0 0.43 0.7102 0.9897 1639660 ChemDiv1_027177 CC(C)c1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D08 compound treatment 693161.0 222000.0 0.46 679999.0 195000.0 0.42 0.6226 0.9992 1982580 ChemDiv1_027178 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2cccs2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D09 compound treatment 760177.0 289000.0 0.6 702312.0 218000.0 0.47 0.7545 0.9932 1603643 ChemDiv1_027179 O=c1n2CCCCc2nc3sc4CCCCc4c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D10 compound treatment 767394.0 296000.0 0.61 709171.0 224000.0 0.49 0.7756 0.9935 1608820 ChemDiv1_027180 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccsc3)sc2=C(C#N)C1c4ccsc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D11 compound treatment 753930.0 283000.0 0.58 725943.0 241000.0 0.52 0.7816 0.9985 1982581 ChemDiv1_027181 Oc1ccc(cc1O)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D12 compound treatment 855685.0 384000.0 0.79 795637.0 311000.0 0.67 1.0368 0.9966 1982582 ChemDiv1_027182 CSc1ccc(cc1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D13 compound treatment 794034.0 323000.0 0.67 723200.0 238000.0 0.52 0.8359 0.992 1982583 ChemDiv1_027183 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D14 compound treatment 769291.0 298000.0 0.62 719835.0 235000.0 0.51 0.7947 0.9956 1481822 ChemDiv1_027184 COc1ccc(CCN2C(N(O)C(=O)NC(C)C)C(C)(C)SC2=S)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D15 compound treatment 792052.0 321000.0 0.66 745347.0 261000.0 0.56 0.8669 0.9968 1479393 ChemDiv1_027185 CCN1C(=O)N(CC)C2(O)c3ccccc3C(=O)C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D16 compound treatment 944570.0 473000.0 0.98 885448.0 401000.0 0.87 1.304 0.9982 1982584 ChemDiv1_027186 COc1ccc(cc1OC)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D17 compound treatment 794314.0 323000.0 0.67 728997.0 244000.0 0.53 0.8452 0.9934 1264729 ChemDiv1_027187 Brc1ccc(s1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D18 compound treatment 744559.0 273000.0 0.56 686212.0 201000.0 0.44 0.7071 0.9919 1982585 ChemDiv1_027188 CCN(CC)Cc1c(nnn1c2nonc2N)C(=O)N/N=C/C3CCC=CC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D19 compound treatment 953145.0 482000.0 0.99 842552.0 358000.0 0.77 1.2508 0.9923 1982586 ChemDiv1_027189 Fc1ccc2N3[C@@H]([C@@H](c4ccccc4F)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D20 compound treatment 750249.0 279000.0 0.58 692480.0 208000.0 0.45 0.725 0.9925 1982587 ChemDiv1_027190 CCOC(=O)c1ccc(cc1)N2C(=N/C(=N\c3cccc(C)c3)/C42CCCCC4)SC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D21 compound treatment 1148015.0 677000.0 1.4 1141715.0 657000.0 1.42 1.9931 1.0 1982588 ChemDiv1_027191 CC(=O)[C@H]1[C@H](c2cccs2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D22 compound treatment 707845.0 236000.0 0.49 685987.0 201000.0 0.44 0.6532 0.9984 1982589 ChemDiv1_027192 Cc1cccc(Nc2nc3nonc3[nH]c2=N/N=C/c4cc5OCOc5cc4Br)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D23 mock treatment 707995.0 237000.0 0.49 695540.0 211000.0 0.46 0.668 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 D24 mock treatment 212679.0 -259000.0 -0.53 213716.0 -271000.0 -0.59 -0.7924 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E01 compound treatment 649886.0 179000.0 0.37 599812.0 115000.0 0.25 0.4367 0.9818 1523827 ChemDiv1_027193 CCCn1cnc2sc(C(=O)N3CCN(CC)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E02 compound treatment 765107.0 294000.0 0.61 685277.0 201000.0 0.43 0.7357 0.9866 1507642 ChemDiv1_027194 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E03 compound treatment 714320.0 243000.0 0.5 665513.0 181000.0 0.39 0.6313 0.9925 1982590 ChemDiv1_027195 CCOCCn1cnc2sc(C(=O)NC3CCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E04 compound treatment 734825.0 263000.0 0.54 701852.0 217000.0 0.47 0.7168 0.9973 1982591 ChemDiv1_027196 O=C([C@@H]1[C@@H]2C3COC(O3)C(=O)[C@H]2[C@H]4N1C=Cc5ccccc45)C6(CC7CC8CC(C7)C6)C8 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E05 compound treatment 738683.0 267000.0 0.55 709568.0 225000.0 0.49 0.7343 0.998 1982592 ChemDiv1_027197 CCOCCn1cnc2sc(C(=O)NCCOC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E06 compound treatment 701566.0 230000.0 0.48 673413.0 189000.0 0.41 0.6248 0.9971 1697983 ChemDiv1_027198 CCS(=O)(=O)c1c(C(=O)c2ccc(C)cc2)n3ccc(cc3c1S(=O)(=O)CC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E07 compound treatment 720157.0 249000.0 0.51 690271.0 206000.0 0.44 0.6777 0.9974 1982593 ChemDiv1_027199 CCOCCn1cnc2sc(C(=O)NCC(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E08 compound treatment 735267.0 264000.0 0.54 736502.0 252000.0 0.54 0.7705 1.0 1476146 ChemDiv1_027200 CCS(=O)(=O)c1c(C(=O)c2ccccc2)n3ccc4ccccc4c3c1S(=O)(=O)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E09 compound treatment 757897.0 287000.0 0.59 735497.0 251000.0 0.54 0.802 0.9991 1982594 ChemDiv1_027201 CCOCCn1cnc2sc(C(=O)N3CCOCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E10 compound treatment 731411.0 260000.0 0.54 702077.0 217000.0 0.47 0.7122 0.9978 1982595 ChemDiv1_027202 CC1(C)OCC(O1)[C@H]2O[C@@H]3OC(C)(C)OC3C2OC(=O)Nc4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E11 compound treatment 753818.0 282000.0 0.58 749259.0 265000.0 0.57 0.8171 1.0 1982596 ChemDiv1_027203 CC(=O)NC1C(O)C2OC(C)(C)OCC2OC1OCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E12 compound treatment 768886.0 298000.0 0.61 704542.0 220000.0 0.48 0.7707 0.992 1982597 ChemDiv1_027204 CC(=O)N(C(=O)C)C1=C(C#N)C2(CCCC2)Cc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E13 compound treatment 760590.0 289000.0 0.6 716617.0 232000.0 0.5 0.777 0.9963 1116124 ChemDiv1_027205 CS(=O)(=O)OCC1OC(C(OS(=O)(=O)C)C1OS(=O)(=O)C)n2ccc(=O)[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E14 compound treatment 735402.0 264000.0 0.55 697570.0 213000.0 0.46 0.7111 0.9965 1347892 ChemDiv1_027206 CC(C)(C)C(C(Oc1ccc(Cl)cc1)n2cncn2)n3nnnc3C4(N)CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E15 compound treatment 765794.0 294000.0 0.61 768519.0 284000.0 0.61 0.8641 1.0 1918987 ChemDiv1_027207 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)C(C)N4CCCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E16 compound treatment 1093809.0 622000.0 1.28 1076532.0 592000.0 1.28 1.8143 1.0 1982598 ChemDiv1_027208 Oc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C4=NC(=O)\C(=C\c5ccc(O)cc5)\S4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E17 compound treatment 761563.0 290000.0 0.6 737594.0 253000.0 0.55 0.8106 0.999 1918320 ChemDiv1_027209 CN(C)CC(=O)N1c2ccccc2CCc3ccc(N)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E18 compound treatment 917373.0 446000.0 0.92 823212.0 338000.0 0.73 1.169 0.9936 1982599 ChemDiv1_027210 Fc1ccccc1[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E19 compound treatment 1023718.0 552000.0 1.14 945459.0 461000.0 1.0 1.5114 0.9978 1982600 ChemDiv1_027211 Clc1cccc(c1)[C@H]2[C@@H](N3[C@@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E20 compound treatment 741749.0 270000.0 0.56 683007.0 198000.0 0.43 0.6981 0.9916 1982601 ChemDiv1_027212 Cc1ccc(cc1Cl)c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E21 compound treatment 749526.0 278000.0 0.57 709056.0 224000.0 0.49 0.7493 0.9965 1982602 ChemDiv1_027213 Cc1cc[n+](cc1)C2C(C(=C(S)NC2(O)C3CC3)C#N)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E22 compound treatment 688317.0 217000.0 0.45 693660.0 209000.0 0.45 0.6364 1.0 1982603 ChemDiv1_027214 CC1(C)SC(=S)N(/N=C/c2ccccc2)C1N(O)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E23 mock treatment 683616.0 212000.0 0.44 705691.0 221000.0 0.48 0.648 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 E24 mock treatment 215266.0 -256000.0 -0.53 178761.0 -306000.0 -0.66 -0.8421 -0.9938 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F01 compound treatment 869313.0 398000.0 0.82 796260.0 312000.0 0.67 1.0576 0.9952 1982604 ChemDiv1_027215 CC(=O)[C@H]1[C@H](c2ccc(Cl)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F02 compound treatment 687605.0 216000.0 0.45 645517.0 161000.0 0.35 0.5617 0.9924 1611677 ChemDiv1_027216 Cc1ccc(cc1)S(=O)(=O)N2CCN(C2c3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F03 compound treatment 477906.0 6540.0 0.01 432909.0 -51800.0 -0.11 -0.0698 -0.6176 1982605 ChemDiv1_027217 Cc1ccc-2c(c1)/C(=C/c3ccccc3)/c4cccnc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F04 compound treatment 718468.0 247000.0 0.51 683219.0 198000.0 0.43 0.6644 0.9963 1307906 ChemDiv1_027218 COC(OC)C1(C2C(C3c4ccccc41)C(=O)N(CCO)C2=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F05 compound treatment 750447.0 279000.0 0.58 674245.0 189000.0 0.41 0.6974 0.9861 1982606 ChemDiv1_027219 CC1=NN(C(=O)C1/C(=N\NC(=O)c2ccccc2)/c3ccc(Br)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F06 compound treatment 743710.0 272000.0 0.56 670969.0 186000.0 0.4 0.6825 0.9867 1505781 ChemDiv1_027220 CC1(C)SC(=S)N(CCN2CCOCC2)C1N(O)C(=O)Nc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F07 compound treatment 826709.0 355000.0 0.73 720678.0 236000.0 0.51 0.8798 0.9843 1616058 ChemDiv1_027221 CC1(C)Cc2ccccc2C3=C(C(=O)N4CCCCC4)C(O)(CC=C)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F08 compound treatment 703207.0 232000.0 0.48 687425.0 203000.0 0.44 0.6486 0.9991 1982607 ChemDiv1_027222 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccc(F)cc2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F09 compound treatment 771703.0 300000.0 0.62 724009.0 239000.0 0.52 0.8046 0.996 1982608 ChemDiv1_027223 FC(F)(F)c1cccc(c1)N2C(=O)C3C(C4C(=O)CC3c5ccccc45)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F10 compound treatment 779765.0 308000.0 0.64 728183.0 243000.0 0.53 0.8227 0.9956 1134769 ChemDiv1_027224 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccco3)sc2=C(C#N)C1c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F11 compound treatment 787836.0 316000.0 0.65 749312.0 265000.0 0.57 0.8668 0.9978 1982609 ChemDiv1_027225 N1C(=Nc2ccccc2C1(c3ccccc3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F12 compound treatment 1182623.0 711000.0 1.47 1161237.0 676000.0 1.46 2.0735 1.0 1982610 ChemDiv1_027226 COc1ccc(cc1)C(=O)[C@@H]2[C@H]3C4COC(O4)C(=O)[C@@H]3[C@H]5C=Cc6ccccc6N25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F13 compound treatment 775373.0 304000.0 0.63 715448.0 231000.0 0.5 0.7968 0.9936 1982611 ChemDiv1_027227 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc([N+](=O)[O-])c(cc4N5CCOCC5)N6CCOCC6)ccc7ccccc37 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F14 compound treatment 778186.0 307000.0 0.63 719421.0 235000.0 0.51 0.807 0.994 1327308 ChemDiv1_027228 Cc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F15 compound treatment 769039.0 298000.0 0.61 762490.0 278000.0 0.6 0.8596 0.9999 1982612 ChemDiv1_027229 Cc1ccc(cc1)C(=O)O/N=C(\Nc2ccccc2C)/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F16 compound treatment 759329.0 288000.0 0.59 740520.0 256000.0 0.55 0.8118 0.9994 1512631 ChemDiv1_027230 Cc1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(Cl)cc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F17 compound treatment 780825.0 309000.0 0.64 749410.0 265000.0 0.57 0.8568 0.9985 1982613 ChemDiv1_027231 [O-][N+](=O)c1ncn(n1)[C@@H]2[C@H](CC(=CC2=O)c3cccs3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F18 compound treatment 738876.0 268000.0 0.55 710680.0 226000.0 0.49 0.7363 0.9982 1982614 ChemDiv1_027232 [O-][N+](=O)c1ccc2OCN3C(OC(c4ccccc4)(c5ccccc5)c6ccccc36)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F19 compound treatment 1177486.0 706000.0 1.46 1108267.0 624000.0 1.35 1.985 0.9993 1982615 ChemDiv1_027233 Fc1ccc(cc1)C(=O)[C@@H]2[C@H]3C4COC(O4)C(=O)[C@@H]3[C@H]5C=Cc6ccccc6N25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F20 compound treatment 759417.0 288000.0 0.59 703874.0 219000.0 0.47 0.7558 0.9937 1982616 ChemDiv1_027234 Cc1cccc(c1)n2nnnc2C3(CCCCC3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F21 compound treatment 828264.0 357000.0 0.74 853597.0 369000.0 0.8 1.0855 0.9992 1982617 ChemDiv1_027235 CC(C)(C)C(=O)[C@H]1[C@H](c2ccc(Cl)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F22 compound treatment 717197.0 246000.0 0.51 714733.0 230000.0 0.5 0.7108 1.0 1168225 ChemDiv1_027236 OCC1OC(CC1O)n2cc(I)c(O)nc2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F23 mock treatment 716303.0 245000.0 0.51 694554.0 210000.0 0.45 0.6786 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 F24 mock treatment 226449.0 -245000.0 -0.51 209674.0 -275000.0 -0.6 -0.7785 -0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G01 compound treatment 648192.0 177000.0 0.37 577522.0 92800.0 0.2 0.4001 0.9604 1982618 ChemDiv1_027237 OC1(C[N+](=C2SCCCN21)c3ccccc3)c4ccc(OC(F)F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G02 compound treatment 750558.0 279000.0 0.58 722865.0 238000.0 0.52 0.772 0.9984 1982619 ChemDiv1_027238 Cc1ccc(cc1)C(=O)[C@H]2[C@H](c3ccccc3)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G03 compound treatment 693271.0 222000.0 0.46 646577.0 162000.0 0.35 0.5716 0.9912 1982620 ChemDiv1_027239 CCOCCn1cnc2sc(C(=O)N(C)C3CCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G04 compound treatment 1182826.0 711000.0 1.47 1152168.0 667000.0 1.44 2.06 1.0 1982621 ChemDiv1_027240 Cc1ccc(cc1)C(=O)[C@@H]2[C@H]3C4COC(O4)C(=O)[C@@H]3[C@H]5C=Cc6ccccc6N25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G05 compound treatment 732883.0 262000.0 0.54 670577.0 186000.0 0.4 0.6661 0.9895 1982622 ChemDiv1_027241 CCOCCn1cnc2sc(C(=O)NC(C)C)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G06 compound treatment 709124.0 238000.0 0.49 679133.0 194000.0 0.42 0.6445 0.9971 1982623 ChemDiv1_027242 NC(=O)[C@H]1[C@H](c2ccc(Cl)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G07 compound treatment 737351.0 266000.0 0.55 698480.0 214000.0 0.46 0.7154 0.9964 1982624 ChemDiv1_027243 CCCCN(C)C(=O)c1sc2ncn(CCOCC)c(=O)c2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G08 compound treatment 729488.0 258000.0 0.53 705717.0 221000.0 0.48 0.715 0.9985 1358171 ChemDiv1_027244 CCC1CN(C)CCC1(OC(=O)CC)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G09 compound treatment 757130.0 286000.0 0.59 730747.0 246000.0 0.53 0.7936 0.9987 1442185 ChemDiv1_027245 COCCn1cnc2sc(C(=O)NC3CCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G10 compound treatment 742560.0 271000.0 0.56 648781.0 164000.0 0.36 0.6469 0.9758 1577324 ChemDiv1_027246 CC(C)OC(=O)C1=C(N)SC(C1c2ccccc2)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G11 compound treatment 729691.0 258000.0 0.53 714431.0 230000.0 0.5 0.7286 0.9994 1982625 ChemDiv1_027247 CC(=O)NC1C(O)C2OC(OCC2OC1OCc3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G12 compound treatment 737537.0 266000.0 0.55 711838.0 227000.0 0.49 0.7361 0.9985 1982626 ChemDiv1_027248 CSc1nc(nc2-c3ccccc3CC4(CCCCC4)c12)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G13 compound treatment 768201.0 297000.0 0.61 731733.0 247000.0 0.53 0.8113 0.9977 1982627 ChemDiv1_027249 COc1ccc(cc1)C(OCC2OC(CC2OS(=O)(=O)C)n3cc(C)c(=O)[nH]c3=O)(c4ccccc4)c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G14 compound treatment 756501.0 285000.0 0.59 738683.0 254000.0 0.55 0.8048 0.9994 1982628 ChemDiv1_027250 CC1(C)Cc2c(CO1)sc3c2c(=O)n(c4ccccc4)c5nncn53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G15 compound treatment 766888.0 296000.0 0.61 744369.0 260000.0 0.56 0.8287 0.9992 1229837 ChemDiv1_027251 CCOC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN(CC)CC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G16 compound treatment 778406.0 307000.0 0.63 717033.0 232000.0 0.5 0.8037 0.9934 1687115 ChemDiv1_027252 Cc1ccc(N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G17 compound treatment 775984.0 305000.0 0.63 736412.0 252000.0 0.54 0.8298 0.9974 1919246 ChemDiv1_027253 CN1CCN(CCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G18 compound treatment 737870.0 267000.0 0.55 727996.0 243000.0 0.53 0.7613 0.9998 1391051 ChemDiv1_027254 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G19 compound treatment 780061.0 309000.0 0.64 747286.0 263000.0 0.57 0.8524 0.9984 1982629 ChemDiv1_027255 NC(=O)[C@H]1[C@H](c2ccc(Cl)c(Cl)c2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G20 compound treatment 746350.0 275000.0 0.57 709687.0 225000.0 0.49 0.7456 0.9971 1982630 ChemDiv1_027256 C[C@]1(O)NC(=C(C#N)[C@@H]([C@H]1[n+]2ccccc2)c3ccc(F)cc3)[C-](C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G21 compound treatment 742920.0 272000.0 0.56 713749.0 229000.0 0.5 0.7469 0.9981 1982631 ChemDiv1_027257 Cc1ccc[n+](c1)C2C(C(=C(S)NC2(O)C3CC3)C#N)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G22 compound treatment 715640.0 244000.0 0.5 681704.0 197000.0 0.43 0.658 0.9965 1269892 ChemDiv1_027258 CNC(=O)N(O)C1N(C)C(=O)N(CCC2=CCCCC2)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G23 mock treatment 691260.0 220000.0 0.45 701250.0 216000.0 0.47 0.6523 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 G24 mock treatment 214753.0 -257000.0 -0.53 250419.0 -234000.0 -0.51 -0.7332 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H01 compound treatment 842898.0 372000.0 0.77 828179.0 343000.0 0.74 1.0679 0.9999 1982632 ChemDiv1_027259 CC(=O)[C@H]1[C@H](c2ccc(Br)cc2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H02 compound treatment 678340.0 207000.0 0.43 639274.0 155000.0 0.33 0.5386 0.9927 1161838 ChemDiv1_027260 COCON1C(N(CC1=O)C(=O)C)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H03 compound treatment 535343.0 64000.0 0.13 492723.0 7970.0 0.02 0.1056 0.7927 1982633 ChemDiv1_027261 Cc1ccc-2c(c1)/C(=C/c3ccc4OCOc4c3)/c5cccnc52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H04 compound treatment 705284.0 234000.0 0.48 645293.0 161000.0 0.35 0.5871 0.987 1127193 ChemDiv1_027262 CCOc1ccccc1N2C(=O)C3C(C2=O)C4(C(OC)OC)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H05 compound treatment 539717.0 68400.0 0.14 473822.0 -10900.0 -0.02 0.083 0.5804 1982634 ChemDiv1_027263 CCCOC=C1c2cc(cc([N+](=O)[O-])c2-c3c1cc(cc3[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H06 compound treatment 759435.0 288000.0 0.59 683340.0 199000.0 0.43 0.7244 0.9873 1335078 ChemDiv1_027264 Cc1ccccc1N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H07 compound treatment 724216.0 253000.0 0.52 703931.0 219000.0 0.47 0.7045 0.9989 1982635 ChemDiv1_027265 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(O)c(c4)[N+](=O)[O-])c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H08 compound treatment 724580.0 253000.0 0.52 707767.0 223000.0 0.48 0.7109 0.9992 1982636 ChemDiv1_027266 [O-][N+](=O)c1ncn(n1)[C@@H]2[C@H](CC(=CC2=O)/C=C/c3cccs3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H09 compound treatment 762978.0 292000.0 0.6 755140.0 270000.0 0.59 0.8395 0.9999 1260255 ChemDiv1_027267 CCN(CC)c1ccc(C2N(Cc3ccccc3)CCN2Cc4ccccc4)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H10 compound treatment 717358.0 246000.0 0.51 681353.0 197000.0 0.43 0.66 0.9961 1707247 ChemDiv1_027268 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3cccc(Br)c3)sc2=C(C#N)C1c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H11 compound treatment 742194.0 271000.0 0.56 729284.0 245000.0 0.53 0.7696 0.9996 1982637 ChemDiv1_027269 CCc1ccc(cc1)C2=NN(c3ccccc3)C4(SC(=NN4c5ccc(Cl)cc5)C(=O)C)c6ccccc26 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H12 compound treatment 934148.0 463000.0 0.96 765757.0 281000.0 0.61 1.1056 0.9762 1982638 ChemDiv1_027270 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccsc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H13 compound treatment 758082.0 287000.0 0.59 711319.0 227000.0 0.49 0.7653 0.9956 1982639 ChemDiv1_027271 [O-][N+](=O)c1cn(cn1)[C@@H]2[C@H](CC(=CC2=O)/C=C/c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H14 compound treatment 761077.0 290000.0 0.6 734791.0 250000.0 0.54 0.8056 0.9988 1251473 ChemDiv1_027272 Cn1c2nnnn2c(=O)c3c4CC(C)(C)OCc4sc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H15 compound treatment 793674.0 322000.0 0.67 729156.0 244000.0 0.53 0.8445 0.9935 1940351 ChemDiv1_027273 CC1=NN(C(=O)C1C(C(C#N)C#N)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H16 compound treatment 728600.0 257000.0 0.53 700370.0 216000.0 0.47 0.7055 0.9979 1935646 ChemDiv1_027274 O=S(=O)(c1cccc2ccccc12)n3nnc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H17 compound treatment 743928.0 273000.0 0.56 747136.0 262000.0 0.57 0.7994 1.0 1649925 ChemDiv1_027275 COC(=O)N1CC(=O)N(OCN2C(=O)c3ccccc3C2=O)C1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H18 compound treatment 724585.0 253000.0 0.52 718255.0 234000.0 0.51 0.727 0.9999 1982640 ChemDiv1_027276 COC(=O)C1=NNC2(C1C(=O)N(C2=O)c3ccccc3)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H19 compound treatment 751359.0 280000.0 0.58 735571.0 251000.0 0.54 0.7926 0.9995 1982641 ChemDiv1_027277 Clc1ccc(C(=O)N/C(=C/c2ccccc2)/C(=O)NCc3ccco3)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H20 compound treatment 706922.0 236000.0 0.49 703438.0 219000.0 0.47 0.6785 0.9999 1982642 ChemDiv1_027278 Fc1cccc(F)c1CSc2nnc(c3ccco3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H21 compound treatment 846907.0 376000.0 0.78 862307.0 378000.0 0.82 1.126 0.9997 1982643 ChemDiv1_027279 CC(C)(C)C(=O)[C@H]1[C@H](c2cccs2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H22 compound treatment 696473.0 225000.0 0.46 673399.0 189000.0 0.41 0.6173 0.9979 1545950 ChemDiv1_027280 Cc1cc(I)ccc1NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H23 mock treatment 691839.0 220000.0 0.46 694973.0 210000.0 0.45 0.6436 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 H24 mock treatment 263519.0 -208000.0 -0.43 229842.0 -255000.0 -0.55 -0.6935 -0.9923 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I01 compound treatment 642847.0 171000.0 0.35 570334.0 85600.0 0.19 0.3813 0.9544 1982644 ChemDiv1_027281 OC1(C[N+](=C2SCCCN21)c3ccc(Br)cc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I02 compound treatment 683282.0 212000.0 0.44 669233.0 184000.0 0.4 0.5917 0.999 1982645 ChemDiv1_027282 Cc1ccc(cc1)[C@]2(O)NC(=C(C#N)[C@@H]([C@H]2[n+]3ccccc3)c4ccc(F)cc4)S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I03 compound treatment 701001.0 230000.0 0.47 654044.0 169000.0 0.37 0.5943 0.9919 1982646 ChemDiv1_027283 CCOCCn1cnc2sc(C(=O)N3CCC(CC3)C(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I04 compound treatment 910089.0 439000.0 0.91 858181.0 373000.0 0.81 1.2119 0.9984 1982647 ChemDiv1_027284 NC1=C(C#N)C2=CCCC[C@H]2[C@H](c3ccccc3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I05 compound treatment 715995.0 245000.0 0.5 703849.0 219000.0 0.47 0.6924 0.9995 1982648 ChemDiv1_027285 CCOCCn1cnc2sc(C(=O)NCCCOC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I06 compound treatment 749457.0 278000.0 0.57 655430.0 171000.0 0.37 0.6671 0.9773 1982649 ChemDiv1_027286 CCOc1ccc(C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5)c(OCC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I07 compound treatment 739064.0 268000.0 0.55 706595.0 222000.0 0.48 0.7303 0.9975 1982650 ChemDiv1_027287 CCOCCn1cnc2sc(C(=O)N3CCC4(CC3)OCCO4)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I08 compound treatment 1414453.0 943000.0 1.95 1611372.0 1130000.0 2.44 3.1008 0.9938 1982651 ChemDiv1_027288 Clc1ccc(cc1)C(=O)[C@H]2[C@H](c3cccc4ccccc34)C(C#N)(C#N)[C@H]5N2C=Cc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I09 compound treatment 744467.0 273000.0 0.56 708343.0 224000.0 0.48 0.7408 0.9971 1483147 ChemDiv1_027289 CCC(C)NC(=O)c1sc2ncn(CCOC)c(=O)c2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I10 compound treatment 814939.0 344000.0 0.71 777678.0 293000.0 0.63 0.9498 0.9984 1982652 ChemDiv1_027290 Cc1cc(c2c(n1)sc3c(O)cc(=O)[nH]c32)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I11 compound treatment 758379.0 287000.0 0.59 693640.0 209000.0 0.45 0.7386 0.9911 1215879 ChemDiv1_027291 NNC(=O)CN1C(=O)CN=C(c2ccccc2)c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I12 compound treatment 722048.0 251000.0 0.52 702230.0 217000.0 0.47 0.6988 0.9989 1467931 ChemDiv1_027292 O=C1C2C(C3c4ccccc4C2c5ccccc35)C(=O)N1CNCc6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I13 compound treatment 749742.0 278000.0 0.57 707471.0 223000.0 0.48 0.7472 0.9962 1982653 ChemDiv1_027293 COc1ccc(cc1)C(OCC2OC(C(O)C2O[Si](C)(C)C(C)(C)C)n3ccc(=O)[nH]c3=O)(c4ccccc4)c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I14 compound treatment 878908.0 408000.0 0.84 826094.0 341000.0 0.74 1.1173 0.9979 1982654 ChemDiv1_027294 Brc1ccc(cc1)[C@@H]2[C@H](N3[C@H](C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I15 compound treatment 760159.0 289000.0 0.6 747969.0 263000.0 0.57 0.8244 0.9997 1457841 ChemDiv1_027295 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc3CCc4ccccc4N(C(=O)CCN(C)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I16 compound treatment 726593.0 255000.0 0.53 693450.0 209000.0 0.45 0.692 0.9971 1039224 ChemDiv1_027296 c1ccc(cc1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I17 compound treatment 776184.0 305000.0 0.63 725359.0 241000.0 0.52 0.8132 0.9956 1982655 ChemDiv1_027297 OCCN1CCN(CCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I18 compound treatment 735991.0 265000.0 0.55 713707.0 229000.0 0.5 0.7367 0.9988 1982656 ChemDiv1_027298 FC(F)(F)c1cccc(/N=C/2\NC(=S)N(CC#N)C32CCCCC3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I19 compound treatment 1023043.0 552000.0 1.14 985589.0 501000.0 1.08 1.5718 0.9997 1431710 ChemDiv1_027299 O=C(C1CC1)C2C(c3ccccc3)C(C#N)(C#N)C4C=CC(=CN24)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I20 compound treatment 741903.0 271000.0 0.56 722107.0 237000.0 0.51 0.7582 0.9991 1382384 ChemDiv1_027300 Clc1ccccc1Nc2nc3nonc3n4cnnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I21 compound treatment 899998.0 429000.0 0.88 994843.0 510000.0 1.1 1.4063 0.994 1982657 ChemDiv1_027301 Cc1cc[n+](cc1)C2C(C(=C(S)NC2(O)C3CC3)C#N)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I22 compound treatment 701510.0 230000.0 0.48 677730.0 193000.0 0.42 0.6313 0.9979 1982658 ChemDiv1_027302 CC1(C)SC(=S)N(/N=C/c2ccc(O)cc2)C1N(O)C(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I23 mock treatment 699639.0 228000.0 0.47 710335.0 226000.0 0.49 0.6785 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 I24 mock treatment 226596.0 -245000.0 -0.51 189254.0 -295000.0 -0.64 -0.8095 -0.9932 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J01 compound treatment 660589.0 189000.0 0.39 605616.0 121000.0 0.26 0.4612 0.981 1210834 ChemDiv1_027303 Cc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J02 compound treatment 649527.0 178000.0 0.37 637636.0 153000.0 0.33 0.494 0.9986 1982659 ChemDiv1_027304 N1C(c2ccccc2)c3c(N=C1c4ccccc4)ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J03 compound treatment 655278.0 184000.0 0.38 656607.0 172000.0 0.37 0.5315 0.9999 1982660 ChemDiv1_027305 Cc1ccccc1/N=C\2/c3ccccc3-c4ncccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J04 compound treatment 679602.0 208000.0 0.43 659177.0 174000.0 0.38 0.5709 0.9979 1982661 ChemDiv1_027306 CSC1=N/C(=N\c2cccc(C)c2)/C3(CCCC3)N1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J05 compound treatment 703839.0 232000.0 0.48 709980.0 225000.0 0.49 0.684 1.0 1694977 ChemDiv1_027307 OC1=C(C(N(C1=O)c2ccc(Br)cn2)c3ccccc3)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J06 compound treatment 700848.0 229000.0 0.47 686002.0 201000.0 0.44 0.643 0.9991 1982662 ChemDiv1_027308 Brc1ccc(cc1)C2=Nc3ccccc3SC(C2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J07 compound treatment 740764.0 269000.0 0.56 695449.0 211000.0 0.46 0.7157 0.9951 1982663 ChemDiv1_027309 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(OCc5ccccc5)cc4)c(=O)n(c6ccccc6)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J08 compound treatment 749818.0 278000.0 0.57 739663.0 255000.0 0.55 0.7966 0.9998 1982664 ChemDiv1_027310 Cc1ccccc1C(=O)Nc2ccc3C4C=CCC4CN5CC6CC=CC6c2c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J09 compound treatment 746929.0 276000.0 0.57 732761.0 248000.0 0.54 0.7818 0.9996 1327748 ChemDiv1_027311 C(N1CCN(Cc2ccccc2)C1c3cccc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J10 compound treatment 893169.0 422000.0 0.87 864655.0 380000.0 0.82 1.1971 0.9996 1982665 ChemDiv1_027312 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccc(Br)c3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J11 compound treatment 734842.0 263000.0 0.54 736895.0 252000.0 0.55 0.7705 1.0 1982666 ChemDiv1_027313 COc1ccc(cc1)C(OCC2OC(CC2O)n3cc(C)c(=O)[nH]c3=O)(c4ccccc4)c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J12 compound treatment 2515748.0 2040000.0 4.22 1796242.0 1310000.0 2.84 4.9913 0.9814 1129543 ChemDiv1_027314 CC(C)(C)C(=O)[C@@H]1[C@@H](c2cccnc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J13 compound treatment 783951.0 313000.0 0.65 1307927.0 823000.0 1.78 1.7161 0.9056 1982667 ChemDiv1_027315 O=C1C=C(C[C@@H]([C@H]1n2nnc3ccccc23)c4cccs4)/C=C/c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J14 compound treatment 752824.0 281000.0 0.58 726708.0 242000.0 0.52 0.7811 0.9987 1504466 ChemDiv1_027316 COCON1C(N(CC1=O)C(=O)OC)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J15 compound treatment 763261.0 292000.0 0.6 767823.0 283000.0 0.61 0.8593 1.0 1584021 ChemDiv1_027317 CC(C)(C)C(C(Oc1ccc(Cl)cc1)n2cncn2)n3nnnc3C(N4CCCCC4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J16 compound treatment 743779.0 272000.0 0.56 730105.0 245000.0 0.53 0.7731 0.9996 1392961 ChemDiv1_027318 COC(=O)COc1ccc(cc1)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J17 compound treatment 751066.0 280000.0 0.58 705191.0 220000.0 0.48 0.7456 0.9955 1140729 ChemDiv1_027319 CSCON1C(N(CC1=O)C(=O)C)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J18 compound treatment 742851.0 271000.0 0.56 746657.0 262000.0 0.57 0.7971 1.0 1278424 ChemDiv1_027320 CC1(C2C(C3c4ccccc41)C(=O)N(CCO)C2=O)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J19 compound treatment 900233.0 429000.0 0.89 920646.0 436000.0 0.94 1.2931 0.9995 1982668 ChemDiv1_027321 FC(F)(F)c1ccccc1[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J20 compound treatment 863943.0 393000.0 0.81 870418.0 386000.0 0.83 1.1633 0.9999 1982669 ChemDiv1_027322 O=C([C@@H]1[C@@H](c2cccnc2)C(C#N)(C#N)[C@@H]3N1C=Cc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J21 compound treatment 853832.0 382000.0 0.79 812408.0 328000.0 0.71 1.0597 0.9986 1982670 ChemDiv1_027323 Ic1ccccc1C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J22 compound treatment 709066.0 238000.0 0.49 718372.0 234000.0 0.51 0.7045 0.9999 1982671 ChemDiv1_027324 CCOC(=O)C1(C)C=C(Nc2cccc(c2)C(F)(F)F)C(=O)N1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J23 mock treatment 700035.0 229000.0 0.47 720582.0 236000.0 0.51 0.6947 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 J24 mock treatment 227130.0 -244000.0 -0.5 209663.0 -275000.0 -0.6 -0.7775 -0.9966 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K01 compound treatment 653460.0 182000.0 0.38 578687.0 93900.0 0.2 0.4096 0.9584 1338596 ChemDiv1_027325 Cc1c(sc2nc3ccccc3c(=O)n12)C(=O)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K02 compound treatment 704408.0 233000.0 0.48 640858.0 156000.0 0.34 0.5791 0.9851 1267667 ChemDiv1_027326 COc1ccc(cc1OC)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K03 compound treatment 699178.0 228000.0 0.47 643087.0 158000.0 0.34 0.5749 0.9879 1982672 ChemDiv1_027327 CCOCCn1cnc2sc(C(=O)N3CCCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K04 compound treatment 683582.0 212000.0 0.44 640824.0 156000.0 0.34 0.5486 0.9918 1982673 ChemDiv1_027328 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(C)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K05 compound treatment 712023.0 241000.0 0.5 666566.0 182000.0 0.39 0.6295 0.9933 1982674 ChemDiv1_027329 CCOCCn1cnc2sc(C(=O)NCCCN(CC)CC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K06 compound treatment 700818.0 229000.0 0.47 628729.0 144000.0 0.31 0.5553 0.9794 1268071 ChemDiv1_027330 O=C(ON1C(N(CC1=O)C(=O)c2ccco2)c3ccccc3)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K07 compound treatment 724788.0 253000.0 0.52 664565.0 180000.0 0.39 0.6451 0.9894 1982675 ChemDiv1_027331 CCOCCn1cnc2sc(C(=O)N3CC(C)CC(C)C3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K08 compound treatment 696197.0 225000.0 0.46 678688.0 194000.0 0.42 0.625 0.9987 1982676 ChemDiv1_027332 COc1ccc(/N=C/C2(C3C(C4c5ccccc52)C(=O)N(C3=O)c6ccccc6Cl)c7ccccc47)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K09 compound treatment 736311.0 265000.0 0.55 668922.0 184000.0 0.4 0.6686 0.9879 1648736 ChemDiv1_027333 CCOC(=O)C1CCN(CC1)C(=O)c2sc3ncn(CCOC)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K10 compound treatment 712658.0 241000.0 0.5 684539.0 200000.0 0.43 0.658 0.9975 1337636 ChemDiv1_027334 CN(C)c1ccc(cc1)C2N3CC4(C)CN2CC(C)(C3)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K11 compound treatment 747483.0 276000.0 0.57 693625.0 209000.0 0.45 0.7227 0.9934 1001900 ChemDiv1_027335 Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K12 compound treatment 728133.0 257000.0 0.53 655755.0 171000.0 0.37 0.6365 0.9846 1982677 ChemDiv1_027336 ON1C(N(CC1=O)C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K13 compound treatment 761202.0 290000.0 0.6 718073.0 233000.0 0.5 0.7802 0.9964 1982678 ChemDiv1_027337 COc1ccc(cc1)C(OCC2OC(C(O[Si](C)(C)C(C)(C)C)C2O)n3ccc(NC(=O)c4ccccc4)nc3=O)(c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K14 compound treatment 726254.0 255000.0 0.53 703480.0 219000.0 0.47 0.7068 0.9986 1655776 ChemDiv1_027338 Cn1c(=O)[nH]c(=O)c2c3CC(C)(C)OCc3sc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K15 compound treatment 751886.0 281000.0 0.58 706063.0 221000.0 0.48 0.7482 0.9956 1584409 ChemDiv1_027339 CC(C)OC(=O)Nc1ccc2CCc3ccccc3N(C(=O)CCN4CCCCC4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K16 compound treatment 742172.0 271000.0 0.56 715188.0 230000.0 0.5 0.748 0.9984 1471525 ChemDiv1_027340 CC(C)Sc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K17 compound treatment 778149.0 307000.0 0.63 724221.0 239000.0 0.52 0.8143 0.9951 1219687 ChemDiv1_027341 O=C(Nc1ccc2CCc3ccccc3Nc2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K18 compound treatment 735739.0 264000.0 0.55 696051.0 211000.0 0.46 0.7093 0.9961 1982679 ChemDiv1_027342 CCSc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K19 compound treatment 772468.0 301000.0 0.62 713908.0 229000.0 0.5 0.7902 0.9937 1982680 ChemDiv1_027343 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4ccc(Cl)c(Cl)c4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K20 compound treatment 733998.0 263000.0 0.54 704275.0 220000.0 0.48 0.7193 0.9978 1546841 ChemDiv1_027344 O=C(CSc1nnc2c3ccccc3[nH]c2n1)CSc4nnc5c6ccccc6[nH]c5n4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K21 compound treatment 795597.0 324000.0 0.67 783684.0 299000.0 0.65 0.9308 0.9999 1982681 ChemDiv1_027345 OC1(NC(=C(C#N)C(C1[n+]2ccccc2)c3ccccc3Br)S)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K22 compound treatment 1031959.0 561000.0 1.16 1069801.0 585000.0 1.27 1.7137 0.999 1982682 ChemDiv1_027346 COc1cccc(/N=C\c2ccc(O)c3[C@H](C(=C(N)Oc23)C#N)c4ccccc4[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K23 mock treatment 706094.0 235000.0 0.48 699735.0 215000.0 0.47 0.6717 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 K24 mock treatment 239759.0 -232000.0 -0.48 212187.0 -273000.0 -0.59 -0.7552 -0.9946 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L01 compound treatment 658592.0 187000.0 0.39 597588.0 113000.0 0.24 0.446 0.9755 1982683 ChemDiv1_027347 CC1(C)C(N(O)C(=O)NC2CCCCC2)N(C3CCCCC3)C(=O)N1CCC4=CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L02 compound treatment 654399.0 183000.0 0.38 646724.0 162000.0 0.35 0.5151 0.9993 1593853 ChemDiv1_027348 CCOC(=O)c1nnn(c1CN2CCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L03 compound treatment 725719.0 254000.0 0.53 737425.0 253000.0 0.55 0.758 0.9998 1982684 ChemDiv1_027349 CCOC(=O)c1c(C)nc(SC)nc1c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L04 compound treatment 682528.0 211000.0 0.44 668857.0 184000.0 0.4 0.59 0.999 1514104 ChemDiv1_027350 Cc1cc2CC(C)(C)NC(=C3C(=O)CC(C)(C)CC3=O)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L05 compound treatment 734971.0 264000.0 0.54 686965.0 202000.0 0.44 0.6943 0.9942 1199383 ChemDiv1_027351 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCCO)C2c3ccc(OC)cc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L06 compound treatment 688238.0 217000.0 0.45 681251.0 196000.0 0.43 0.6173 0.9997 1184642 ChemDiv1_027352 CC1(C)OC(=O)N(CC(=O)O)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L07 compound treatment 685310.0 214000.0 0.44 684241.0 199000.0 0.43 0.6176 0.9999 1287886 ChemDiv1_027353 CC1CN(C(N1c2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L08 compound treatment 698242.0 227000.0 0.47 673846.0 189000.0 0.41 0.6206 0.9977 1688168 ChemDiv1_027354 OC1CC(N(C1)C(=O)Oc2ccccc2)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L09 compound treatment 731844.0 260000.0 0.54 721298.0 237000.0 0.51 0.7422 0.9997 1411345 ChemDiv1_027355 CC1(C)Cc2ccccc2C3=C(C(=O)N4CCOCC4)C(O)(CC=C)C(=O)N31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L10 compound treatment 831847.0 360000.0 0.74 776477.0 292000.0 0.63 0.9727 0.9967 1982685 ChemDiv1_027356 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccc(Cl)cc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L11 compound treatment 735603.0 264000.0 0.55 665835.0 181000.0 0.39 0.6628 0.9869 1982686 ChemDiv1_027357 O=C(NC1=C2C(=O)CCc3c[nH][n+](c23)[B-](N1)(c4ccccc4)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L12 compound treatment 1330907.0 860000.0 1.77 1476047.0 991000.0 2.15 2.7718 0.9955 1982687 ChemDiv1_027358 CC(C)(C)C(=O)[C@@H]1[C@@H](c2ccc(Cl)cc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L13 compound treatment 746413.0 275000.0 0.57 697989.0 213000.0 0.46 0.7278 0.9947 1982688 ChemDiv1_027359 [O-][N+](=O)c1nnn(n1)[C@@H]2[C@H](CC(=CC2=O)c3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L14 compound treatment 728391.0 257000.0 0.53 722720.0 238000.0 0.52 0.7394 0.9999 1579530 ChemDiv1_027360 Cc1ccc(NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L15 compound treatment 766200.0 295000.0 0.61 762526.0 278000.0 0.6 0.8555 1.0 1251897 ChemDiv1_027361 CCOC(=O)COc1ccc(cc1OC)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L16 compound treatment 725517.0 254000.0 0.52 733897.0 249000.0 0.54 0.7523 0.9999 1303388 ChemDiv1_027362 COc1ccc(C2NC(=O)C(=C2C(=O)c3ccccc3)O)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L17 compound treatment 1095412.0 624000.0 1.29 1210436.0 726000.0 1.57 2.0215 0.9952 1488547 ChemDiv1_027363 Clc1ccc(cc1)C(=O)COC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L18 compound treatment 730250.0 259000.0 0.53 772821.0 288000.0 0.62 0.8188 0.9971 1982689 ChemDiv1_027364 OC(=O)C1C2C(Br)C3OC(=O)C1C3C42CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L19 compound treatment 811213.0 340000.0 0.7 853680.0 369000.0 0.8 1.0607 0.9979 1982690 ChemDiv1_027365 O=C([C@H]1[C@H](c2cccs2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L20 compound treatment 742143.0 271000.0 0.56 747610.0 263000.0 0.57 0.7975 1.0 1193526 ChemDiv1_027366 Cc1nnc2c(Nc3cccc(C)c3C)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L21 compound treatment 821306.0 350000.0 0.72 827752.0 343000.0 0.74 1.0357 0.9999 1982691 ChemDiv1_027367 Cc1ccccc1C(=O)[C@@H]2[C@@H](c3ccccc3)C(C#N)(C#N)[C@H]4C=Cc5cc(Cl)ccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L22 compound treatment 713149.0 242000.0 0.5 729196.0 244000.0 0.53 0.727 0.9996 1982692 ChemDiv1_027368 Cc1ccc(c(C)c1)c2cnc3ccccc3[n+]2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L23 mock treatment 702363.0 231000.0 0.48 745802.0 261000.0 0.57 0.7367 0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 L24 mock treatment 204124.0 -267000.0 -0.55 285227.0 -200000.0 -0.43 -0.6955 -0.9927 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M01 compound treatment 637210.0 166000.0 0.34 576666.0 91900.0 0.2 0.3828 0.9666 1982693 ChemDiv1_027369 CC(C)(C)c1ccc(cc1)C2(O)C[N+](=C3SCCCN32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M02 compound treatment 670391.0 199000.0 0.41 630232.0 145000.0 0.31 0.5132 0.9914 1322595 ChemDiv1_027370 CC(C)ON1C(N(CC1=O)C(=O)c2ccccc2)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M03 compound treatment 710758.0 239000.0 0.49 676947.0 192000.0 0.42 0.6436 0.9963 1982694 ChemDiv1_027371 CCOCCn1cnc2sc(C(=O)N3CCN(C)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M04 compound treatment 679821.0 208000.0 0.43 652920.0 168000.0 0.36 0.5617 0.9965 1982695 ChemDiv1_027372 Oc1ccc(cc1)C(Nc2ccc(Cl)cc2)P3(=O)OCCCO3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M05 compound treatment 717187.0 246000.0 0.51 662794.0 178000.0 0.39 0.6313 0.9908 1982696 ChemDiv1_027373 CCOCCn1cnc2sc(C(=O)NC3CCCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M06 compound treatment 710455.0 239000.0 0.49 630215.0 145000.0 0.31 0.5716 0.9764 1158553 ChemDiv1_027374 Brc1cccc(c1)c2c3c(=O)c4ccccc4c3nc5c6ccccc6c(=O)c25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M07 compound treatment 744065.0 273000.0 0.56 689162.0 204000.0 0.44 0.7109 0.9929 1982697 ChemDiv1_027375 CCOCCn1cnc2sc(C(=O)N3CCCC(C3)C(=O)OCC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M08 compound treatment 712211.0 241000.0 0.5 636710.0 152000.0 0.33 0.5841 0.9799 1122160 ChemDiv1_027376 CC1(CN2CC3(C)CN(C1)C2c4cn(Cc5ccccc5)c6ccccc46)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M09 compound treatment 737104.0 266000.0 0.55 691156.0 206000.0 0.45 0.7038 0.9948 1159040 ChemDiv1_027377 COCCn1cnc2sc(C(=O)N3CCCCCC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M10 compound treatment 707367.0 236000.0 0.49 677630.0 193000.0 0.42 0.6397 0.997 1176620 ChemDiv1_027378 Nc1nc2nonc2n3nnnc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M11 compound treatment 742463.0 271000.0 0.56 701975.0 217000.0 0.47 0.7282 0.9962 1554034 ChemDiv1_027379 OC(=O)C1C(C2CCC1C2)C(=O)N3CC4CC(C3)c5cccc(=O)n5C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M12 compound treatment 702654.0 231000.0 0.48 656902.0 172000.0 0.37 0.6011 0.9925 1333980 ChemDiv1_027380 COc1ccc(cc1OC)C(C2C(=O)CC(C)(C)CC2=O)C3=C(O)CC(C)(C)CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M13 compound treatment 683675.0 212000.0 0.44 596207.0 111000.0 0.24 0.4805 0.9604 1982698 ChemDiv1_027381 CC(C)(C)[Si](C)(C)OCC1OC(CC1O[Si](C)(C)C(C)(C)C)n2ccc(N)nc2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M14 compound treatment 731744.0 260000.0 0.54 690563.0 206000.0 0.45 0.6951 0.9956 1231318 ChemDiv1_027382 CCS(=O)(=O)c1c(C(=O)c2ccccc2)n3cccc(C)c3c1S(=O)(=O)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M15 compound treatment 754042.0 283000.0 0.58 703423.0 219000.0 0.47 0.7473 0.9946 1735521 ChemDiv1_027383 CNCCC(=O)N1c2ccccc2CCc3ccc(NC(=O)OC)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M16 compound treatment 714944.0 244000.0 0.5 683713.0 199000.0 0.43 0.66 0.997 1982699 ChemDiv1_027384 CCOc1ccc(cc1)N2C(=O)C3C(C2=O)C4(/C=N/c5ccccc5C(=O)O)c6ccccc6C3c7ccccc74 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M17 compound treatment 751634.0 280000.0 0.58 711482.0 227000.0 0.49 0.7561 0.9966 1616888 ChemDiv1_027385 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc3CCc4ccccc4Nc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M18 compound treatment 725288.0 254000.0 0.52 696669.0 212000.0 0.46 0.695 0.9978 1249504 ChemDiv1_027386 Cc1c(N(CC(=O)NCc2ccccc2)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M19 compound treatment 780201.0 309000.0 0.64 765969.0 281000.0 0.61 0.8812 0.9997 1982700 ChemDiv1_027387 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4ccncc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M20 compound treatment 716425.0 245000.0 0.51 707845.0 223000.0 0.48 0.6991 0.9997 1692447 ChemDiv1_027388 CC1(C)N(O)C(=O)CN1C(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M21 compound treatment 835332.0 364000.0 0.75 824747.0 340000.0 0.74 1.0516 0.9999 1982701 ChemDiv1_027389 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2cccc3cc(Cl)ccc23)c4ccsc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M22 compound treatment 726035.0 255000.0 0.53 719808.0 235000.0 0.51 0.7315 0.9999 1982702 ChemDiv1_027390 NC(=O)[C@@H]1[C@@H](c2cccc(Br)c2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M23 mock treatment 707823.0 236000.0 0.49 697686.0 213000.0 0.46 0.671 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 M24 mock treatment 395399.0 -76000.0 -0.16 411850.0 -72900.0 -0.16 -0.2225 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N01 compound treatment 646167.0 175000.0 0.36 596277.0 112000.0 0.24 0.4258 0.9809 1224002 ChemDiv1_027391 CC(=O)Oc1cc2oc3CC(C)(C)CC(=O)c3c2cc1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N02 compound treatment 673615.0 202000.0 0.42 644758.0 160000.0 0.35 0.5401 0.9957 1648831 ChemDiv1_027392 CCC1(C)OC(=O)N(CCO)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N03 compound treatment 690750.0 219000.0 0.45 687704.0 203000.0 0.44 0.6308 0.9999 1982703 ChemDiv1_027393 Cc1ccc([N+](=O)[O-])c2cc3C(=O)c4ccccc4-c3nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N04 compound treatment 692783.0 221000.0 0.46 643443.0 159000.0 0.34 0.5661 0.9901 1583902 ChemDiv1_027394 CCC(C)N1C(=O)N(C(n2oc(=O)n(c3cccc(Cl)c3)c2=O)C1(C)C)c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N05 compound treatment 702705.0 231000.0 0.48 687077.0 202000.0 0.44 0.6473 0.9991 1982704 ChemDiv1_027395 CCOC(=O)C1(C)C=C(Nc2ccc(cc2)S(=O)(=O)N)C(=O)N1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N06 compound treatment 665367.0 194000.0 0.4 664341.0 180000.0 0.39 0.558 0.9999 1244129 ChemDiv1_027396 CC(N1C(=O)OC(C)(C)C1(C)O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N07 compound treatment 1477671.0 1010000.0 2.08 1248357.0 764000.0 1.65 2.6375 0.9936 1296963 ChemDiv1_027397 C1C=CC2C1CN3CC4CC=CC4c5cccc2c35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N08 compound treatment 689477.0 218000.0 0.45 664400.0 180000.0 0.39 0.5933 0.9973 1982705 ChemDiv1_027398 Clc1ccc(cc1Cl)N2C(=O)C3C(C4C(=O)CC3c5ccccc45)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N09 compound treatment 681161.0 210000.0 0.43 716053.0 231000.0 0.5 0.6602 0.9974 1594217 ChemDiv1_027399 COc1ccc2C(OC(=O)C)OC(=O)c2c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N10 compound treatment 1908302.0 1440000.0 2.97 2045586.0 1560000.0 3.38 4.4863 0.9979 1982706 ChemDiv1_027400 CC(C)(C)C(=O)[C@@H]1[C@@H](c2ccccc2Cl)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N11 compound treatment 716213.0 245000.0 0.51 708770.0 224000.0 0.48 0.7002 0.9998 1514018 ChemDiv1_027401 CCN1C(=O)N(C(n2oc(=O)n(c3ccc(Cl)cc3)c2=O)C1(C)C)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N12 compound treatment 679085.0 208000.0 0.43 650504.0 166000.0 0.36 0.5569 0.9961 1386871 ChemDiv1_027402 COc1ccc(cc1O)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N13 compound treatment 703105.0 232000.0 0.48 721357.0 237000.0 0.51 0.7004 0.9994 1982707 ChemDiv1_027403 [O-][N+](=O)c1cn(cn1)[C@@H]2[C@H](CC(=CC2=O)/C=C/c3cccs3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N14 compound treatment 716909.0 246000.0 0.51 681276.0 197000.0 0.43 0.6592 0.9962 1108233 ChemDiv1_027404 CCCCCc1nnc2SCC(=Nn12)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N15 compound treatment 713749.0 242000.0 0.5 727480.0 243000.0 0.53 0.7253 0.9997 1982708 ChemDiv1_027405 CCS(=O)(=O)c1c(C(=O)c2ccccc2)n3cc(ccc3c1S(=O)(=O)CC)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N16 compound treatment 698212.0 227000.0 0.47 686916.0 202000.0 0.44 0.6405 0.9994 1324281 ChemDiv1_027406 OC(=O)CCC1(CCC(=O)O)c2ccccc2-c3nc4ccccc4cc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N17 compound treatment 799474.0 328000.0 0.68 731167.0 246000.0 0.53 0.8561 0.993 1591806 ChemDiv1_027407 NC1=C(C#N)C(C(=c2sc(=Cc3ccccc3F)c(=O)n12)C#N)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N18 compound treatment 703474.0 232000.0 0.48 706001.0 221000.0 0.48 0.6774 1.0 1982709 ChemDiv1_027408 OC(=O)C1C2C(Cl)C3OC(=O)C1C3C42CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N19 compound treatment 1192370.0 721000.0 1.49 1343153.0 858000.0 1.86 2.3662 0.994 1982710 ChemDiv1_027409 CC(C)(C)C(=O)[C@@H]1[C@H]2C3COC(O3)C(=O)[C@@H]2[C@H]4C=Cc5ccccc5N14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N20 compound treatment 683200.0 212000.0 0.44 727299.0 243000.0 0.52 0.6804 0.9959 1658671 ChemDiv1_027410 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N21 compound treatment 786091.0 315000.0 0.65 792566.0 308000.0 0.67 0.9305 0.9999 1982711 ChemDiv1_027411 Clc1ccc2N3[C@@H]([C@@H](c4ccccc4)C(C#N)(C#N)[C@H]3C=Cc2c1)C(=O)c5ccsc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N22 compound treatment 691631.0 220000.0 0.45 709259.0 225000.0 0.49 0.6651 0.9994 1037062 ChemDiv1_027412 O=C1c2ccccc2-c3nc4ccccc4cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N23 mock treatment 682311.0 211000.0 0.44 698449.0 214000.0 0.46 0.635 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 N24 mock treatment 253037.0 -218000.0 -0.45 403243.0 -81500.0 -0.18 -0.4434 -0.9162 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O01 compound treatment 674076.0 203000.0 0.42 577329.0 92600.0 0.2 0.4376 0.9431 1982712 ChemDiv1_027413 CCc1ccc(cc1)[N+]2=C3CCCCCN3CC2(O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O02 compound treatment 676833.0 205000.0 0.42 601198.0 116000.0 0.25 0.4781 0.9691 1553164 ChemDiv1_027414 CC(=O)OCC1OC(Sc2ccccn2)C(OC(=O)C)C(OC(=O)C)C1COC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O03 compound treatment 712517.0 241000.0 0.5 637332.0 153000.0 0.33 0.5855 0.9801 1982713 ChemDiv1_027415 CCOCCn1cnc2sc(C(=O)N3CCC(C)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O04 compound treatment 702077.0 231000.0 0.48 622857.0 138000.0 0.3 0.5481 0.9748 1982714 ChemDiv1_027416 CC(=O)[C@@H]1SC(=C(C#N)[C@H]1c2cccs2)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O05 compound treatment 706849.0 235000.0 0.49 663514.0 179000.0 0.39 0.6173 0.9936 1982715 ChemDiv1_027417 CCOCCn1cnc2sc(C(=O)NCCN(CC)CC)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O06 compound treatment 750704.0 279000.0 0.58 697828.0 213000.0 0.46 0.7338 0.9939 1982716 ChemDiv1_027418 Cc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3Cl)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O07 compound treatment 747455.0 276000.0 0.57 680358.0 196000.0 0.42 0.7024 0.9893 1982717 ChemDiv1_027419 CCOCCn1cnc2sc(C(=O)N3CCN(CC)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O08 compound treatment 650749.0 179000.0 0.37 648951.0 164000.0 0.36 0.5131 0.9998 1982718 ChemDiv1_027420 COc1ccc(cc1C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O09 compound treatment 693316.0 222000.0 0.46 669062.0 184000.0 0.4 0.6061 0.9976 1584011 ChemDiv1_027421 CCC1CCCCN1C(=O)c2sc3ncn(CCOC)c(=O)c3c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O10 compound treatment 671782.0 200000.0 0.41 632251.0 147000.0 0.32 0.5183 0.9918 1982719 ChemDiv1_027422 C[C@@H]1CC2C3CC=C4CCCC(OC(=O)C)C4(C)C3CCC2(C)[C@@]1(C)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O11 compound treatment 682422.0 211000.0 0.44 643859.0 159000.0 0.34 0.5516 0.9932 1607776 ChemDiv1_027423 OC(=O)C1CCCCC1C(=O)N2CC3CC(C2)c4cccc(=O)n4C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O12 compound treatment 656929.0 186000.0 0.38 623852.0 139000.0 0.3 0.4837 0.9929 1982720 ChemDiv1_027424 Brc1ccc(/C=N/NC(=O)C2C(C(C2c3ccccc3)C(=O)N4CCOCC4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O13 compound treatment 694528.0 223000.0 0.46 664140.0 179000.0 0.39 0.6003 0.9964 1147219 ChemDiv1_027425 CC(C)OC(=O)Nc1ccc2CCc3ccccc3Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O14 compound treatment 691890.0 221000.0 0.46 640696.0 156000.0 0.34 0.5606 0.9892 1692904 ChemDiv1_027426 CCC(C)N1C(=O)N(C(n2oc(=O)n(c3cccc4ccccc34)c2=O)C1(C)C)c5cccc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O15 compound treatment 729444.0 258000.0 0.53 704321.0 220000.0 0.48 0.7128 0.9984 1917352 ChemDiv1_027427 CN(C)CC(=O)N1c2ccccc2CCc3ccc(NC(=O)c4ccccc4)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O16 compound treatment 692544.0 221000.0 0.46 644758.0 160000.0 0.35 0.5677 0.9907 1776405 ChemDiv1_027428 [O-][N+](=O)c1ccc(Cl)c(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O17 compound treatment 729967.0 259000.0 0.53 686680.0 202000.0 0.44 0.6865 0.9951 1121064 ChemDiv1_027429 CCCC(CCC)C(=O)Nc1ccc2CCc3ccccc3Nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O18 compound treatment 724476.0 253000.0 0.52 698763.0 214000.0 0.46 0.697 0.9982 1982721 ChemDiv1_027430 O=C/1N=C(S\C1=C/c2ccc3OCOc3c2)N4CCN(CC4)C5=NC(=O)/C(=C/c6ccc7OCOc7c6)/S5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O19 compound treatment 705361.0 234000.0 0.48 720436.0 236000.0 0.51 0.7023 0.9996 1982722 ChemDiv1_027431 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccc3ccccc3c2)c4ccc(F)cc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O20 compound treatment 689674.0 218000.0 0.45 679070.0 194000.0 0.42 0.6161 0.9994 1645945 ChemDiv1_027432 O=C(Oc1ccc(cc1)C2NC(=O)c3c4CCCCc4sc3N2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O21 compound treatment 764543.0 293000.0 0.61 746956.0 262000.0 0.57 0.8292 0.9995 1982723 ChemDiv1_027433 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2cccc3cc(Cl)ccc23)c4ccc(F)cc4)S)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O22 compound treatment 728321.0 257000.0 0.53 719530.0 235000.0 0.51 0.7344 0.9998 1399752 ChemDiv1_027434 CC(C)(C)C1CC=C2C(C1)C(c3cccc(Cl)c3)C(C#N)(C#N)C(=C2C#N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O23 mock treatment 682210.0 211000.0 0.44 677564.0 193000.0 0.42 0.6029 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 O24 mock treatment 397483.0 -73900.0 -0.15 436584.0 -48200.0 -0.1 -0.1816 -0.9828 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P01 compound treatment 534874.0 63500.0 0.13 495833.0 11100.0 0.02 0.1097 0.8228 1982724 ChemDiv1_027435 COc1ccc(/C=C/2\c3cccnc3-c4ccc(C)cc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P02 compound treatment 644457.0 173000.0 0.36 582978.0 98200.0 0.21 0.403 0.9692 1982725 ChemDiv1_027436 NC1=C(C#N)[C@H]([C@@H](S1)C(=O)c2ccc(Br)cc2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P03 compound treatment 604884.0 134000.0 0.28 595203.0 110000.0 0.24 0.3639 0.9975 1982726 ChemDiv1_027437 N(=C/1\c2ccccc2-c3nc4ccccc4cc13)/c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P04 compound treatment 634445.0 163000.0 0.34 580261.0 95500.0 0.21 0.3842 0.9726 1471434 ChemDiv1_027438 CC1(C)SC(=S)N(CCN2CCOCC2)C1N(O)C(=O)Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P05 compound treatment 620136.0 149000.0 0.31 595144.0 110000.0 0.24 0.3861 0.9923 1455106 ChemDiv1_027439 COc1ccc(cc1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4ccc(Br)cn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P06 compound treatment 636248.0 165000.0 0.34 605457.0 121000.0 0.26 0.4254 0.9915 1228566 ChemDiv1_027440 CCOC(=O)c1nnn(c1CN2CCC(C)CC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P07 compound treatment 653964.0 183000.0 0.38 621662.0 137000.0 0.3 0.4761 0.9929 1982727 ChemDiv1_027441 Cc1c(Cc2cc3C4C=CCC4CN5CC6CC=CC6c(c2C)c53)cc7C8C=CCC8CN9CC%10CC=CC%10c1c97 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P08 compound treatment 653526.0 182000.0 0.38 619213.0 134000.0 0.29 0.4717 0.992 1982728 ChemDiv1_027442 COc1ccc(cc1)c2oc(NC(=O)C(F)(F)F)c(C#N)c2c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P09 compound treatment 633825.0 162000.0 0.34 609869.0 125000.0 0.27 0.4286 0.9944 1982729 ChemDiv1_027443 CC(C)N1C(=O)C2C(C3C(=O)CC2c4ccccc34)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P10 compound treatment 706233.0 235000.0 0.48 689172.0 204000.0 0.44 0.6557 0.999 1982730 ChemDiv1_027444 CC(C)(C)C(=O)[C@H]1[C@H](c2ccc(Cl)c(Cl)c2)C(C#N)(C#N)[C@H]3N1C=Cc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P11 compound treatment 659190.0 188000.0 0.39 629131.0 144000.0 0.31 0.4951 0.9943 1939026 ChemDiv1_027445 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P12 compound treatment 640415.0 169000.0 0.35 642522.0 158000.0 0.34 0.4882 0.9999 1982731 ChemDiv1_027446 COc1ccc(cc1)N2C(=N/C(=N\c3cccc(C)c3)/C42CCCCC4)SC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P13 compound treatment 637429.0 166000.0 0.34 618019.0 133000.0 0.29 0.4464 0.9963 1982732 ChemDiv1_027447 O=C1C=C(C[C@@H]([C@H]1n2cncn2)c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P14 compound treatment 638416.0 167000.0 0.34 616724.0 132000.0 0.29 0.4458 0.9956 1527855 ChemDiv1_027448 CCOC(=O)c1nnn(c1CN2CCCCC2C)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P15 compound treatment 667474.0 196000.0 0.4 638619.0 154000.0 0.33 0.5217 0.9953 1372744 ChemDiv1_027449 CCC(=O)Cc1nnc2c(Nc3ccc(Cl)cc3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P16 compound treatment 672198.0 201000.0 0.41 648214.0 163000.0 0.35 0.5433 0.9969 1982733 ChemDiv1_027450 COC1=NC(N=C(O1)N2CCCCC2)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P17 compound treatment 676985.0 206000.0 0.42 651452.0 167000.0 0.36 0.5553 0.9967 1405917 ChemDiv1_027451 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3cccc(OC)c3)sc2=C(C#N)C1c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P18 compound treatment 678913.0 208000.0 0.43 646438.0 162000.0 0.35 0.5504 0.995 1982734 ChemDiv1_027452 OC(=O)C1C2C3CCC1C(Cl)C3OC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P19 compound treatment 1830104.0 1360000.0 2.8 1333076.0 848000.0 1.84 3.2816 0.9789 1982735 ChemDiv1_027453 CC(C)(C)C(=O)[C@@H]1[C@@H](c2ccsc2)C(C#N)(C#N)[C@H]3C=Cc4ccccc4N13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P20 compound treatment 668214.0 197000.0 0.41 640974.0 156000.0 0.34 0.5264 0.9958 1183446 ChemDiv1_027454 COc1ccc(cc1OC)c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P21 compound treatment 764519.0 293000.0 0.61 756269.0 272000.0 0.59 0.8435 0.9999 1982736 ChemDiv1_027455 Fc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3c(F)cccc3Cl)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P22 compound treatment 651848.0 180000.0 0.37 627654.0 143000.0 0.31 0.4822 0.9957 1709251 ChemDiv1_027456 C(N1CCN(Cc2ccccc2)C1c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P23 mock treatment 627360.0 156000.0 0.32 627323.0 143000.0 0.31 0.4459 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.664 P24 mock treatment 387116.0 -84200.0 -0.17 479476.0 -5280.0 -0.01 -0.1311 -0.7519 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A01 compound treatment 611487.0 153000.0 0.32 584008.0 122000.0 0.26 0.4101 0.996 1982737 ChemDiv1_027457 OC1(C2CCCCCC2=NN1C(=O)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A02 compound treatment 591384.0 133000.0 0.27 570786.0 109000.0 0.24 0.3606 0.9971 1982738 ChemDiv1_027458 C(Sc1nnc2c3ccccc3[nH]c2n1)/C=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A03 compound treatment 671160.0 213000.0 0.44 628983.0 167000.0 0.36 0.5661 0.9953 1982739 ChemDiv1_027459 Brc1ccccc1[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A04 compound treatment 637004.0 179000.0 0.37 573772.0 112000.0 0.24 0.4317 0.9792 1579545 ChemDiv1_027460 CC1(C)c2ccccc2N(CC(=O)NCc3ccccc3)C41Oc5ccc6ccccc6c5C=C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A05 compound treatment 685243.0 227000.0 0.47 628001.0 166000.0 0.36 0.5851 0.9915 1912494 ChemDiv1_027461 COc1ccc(cc1)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A06 compound treatment 651716.0 193000.0 0.4 601352.0 139000.0 0.3 0.4954 0.9905 1982740 ChemDiv1_027462 Cc1ccc(cc1)N2NC3(CCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A07 compound treatment 654328.0 196000.0 0.4 610424.0 148000.0 0.32 0.5131 0.9935 1982741 ChemDiv1_027463 CCC(=O)N(C)C1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A08 compound treatment 659952.0 201000.0 0.42 618087.0 156000.0 0.34 0.533 0.9947 1870552 ChemDiv1_027464 Cc1ccc(cc1)c2csc(=Nc3ccccc3)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A09 compound treatment 661671.0 203000.0 0.42 623897.0 162000.0 0.35 0.5444 0.996 1982742 ChemDiv1_027465 CN1C(=S)SC(N2OC3C(C2c4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A10 compound treatment 646689.0 188000.0 0.39 632906.0 171000.0 0.37 0.5364 0.9997 1982743 ChemDiv1_027466 Cc1ccc-2c(c1)/C(=N/c3ccccc3)/c4cc5ccccc5nc42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A11 compound treatment 647705.0 189000.0 0.39 605013.0 143000.0 0.31 0.4952 0.9934 1982744 ChemDiv1_027467 Clc1cccc(c1)n2nnnc2C3(CCCC3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A12 compound treatment 792247.0 334000.0 0.69 793922.0 332000.0 0.72 0.9953 0.9998 1982745 ChemDiv1_027468 NC1=C(C#N)C2=CCCCC2C(c3ccccc3F)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A13 compound treatment 662553.0 204000.0 0.42 624014.0 162000.0 0.35 0.5459 0.9958 1464383 ChemDiv1_027469 COC(=O)c1nnn(c1CN2CCCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A14 compound treatment 778293.0 320000.0 0.66 706316.0 244000.0 0.53 0.8408 0.994 1619689 ChemDiv1_027470 Cc1oc2c(c1c3ccccc3)c(=O)oc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A15 compound treatment 651088.0 193000.0 0.4 636916.0 175000.0 0.38 0.5489 0.9997 1982746 ChemDiv1_027471 CC(C)(C)N1C(N(N=C1c2ccccc2)c3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A16 compound treatment 660200.0 202000.0 0.42 621166.0 159000.0 0.34 0.5381 0.9956 1413383 ChemDiv1_027472 Cc1ccc(cc1)C(=O)c2nn(c3ccccc3)c4nc5ccccc5nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A17 compound treatment 670652.0 212000.0 0.44 631419.0 169000.0 0.37 0.5691 0.9961 1573934 ChemDiv1_027473 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccccc4)c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A18 compound treatment 648049.0 190000.0 0.39 632131.0 170000.0 0.37 0.5372 0.9995 1982747 ChemDiv1_027474 C1CCC2(CC1)Cc3ccccc3C(=N2)Nn4cnnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A19 compound treatment 636273.0 178000.0 0.37 635432.0 173000.0 0.38 0.525 0.9999 1982748 ChemDiv1_027475 Clc1ccc(cc1)c2nc3ccccc3nc2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A20 compound treatment 636064.0 178000.0 0.37 633184.0 171000.0 0.37 0.5213 1.0 1982749 ChemDiv1_027476 COc1ccccc1C(=O)N2N=C3N(C2N(C)C)S(=O)(=O)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A21 compound treatment 618328.0 160000.0 0.33 610617.0 149000.0 0.32 0.4609 0.9999 1982750 ChemDiv1_027477 COc1cccc(c1)C2C=C(Nc3ccc(F)cc3)C(=O)N2c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A22 compound treatment 608695.0 150000.0 0.31 580964.0 119000.0 0.26 0.4014 0.9957 1982751 ChemDiv1_027478 CC1(C)c2ccccc2N3CCC(=O)NC31/C=C/c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A23 mock treatment 569782.0 111000.0 0.23 571767.0 110000.0 0.24 0.3305 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 A24 mock treatment 193558.0 -265000.0 -0.55 231958.0 -230000.0 -0.5 -0.7387 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B01 compound treatment 643225.0 185000.0 0.38 575613.0 114000.0 0.25 0.4436 0.9775 1318631 ChemDiv1_027479 COc1cc(ccc1O)C2N(CCN2S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B02 compound treatment 664812.0 206000.0 0.43 611953.0 150000.0 0.32 0.5308 0.991 1982752 ChemDiv1_027480 NC(=S)NN=C1CSc2sc(=O)sc2SC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B03 compound treatment 704228.0 246000.0 0.51 664085.0 202000.0 0.44 0.6681 0.9973 1948712 ChemDiv1_027481 CC(C)(C)c1ccc(C=c2sc3nnc(c4ccccc4)n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B04 compound treatment 683297.0 225000.0 0.46 632375.0 170000.0 0.37 0.589 0.9935 1982753 ChemDiv1_027482 CC12CC(C)(C)NC(=S)N2c3ccccc3N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B05 compound treatment 734277.0 276000.0 0.57 687497.0 226000.0 0.49 0.7478 0.9971 1982754 ChemDiv1_027483 C1CCC2(CC1)Cc3ccccc3C(=N2)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B06 compound treatment 682784.0 224000.0 0.46 628811.0 167000.0 0.36 0.5828 0.9924 1982755 ChemDiv1_027484 O=C(NN=C1CSc2sc(=S)sc2SC1)c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B07 compound treatment 729973.0 272000.0 0.56 700985.0 239000.0 0.52 0.7621 0.9992 1982756 ChemDiv1_027485 COc1ccc(/C=C/C23NC(=O)CN3c4ccccc4C2(C)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B08 compound treatment 694963.0 237000.0 0.49 691185.0 229000.0 0.5 0.696 1.0 1415400 ChemDiv1_027486 CC1(C)Nc2ccccc2-c3c1sn(Cc4ccc(Cl)cc4)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B09 compound treatment 755334.0 297000.0 0.61 705692.0 244000.0 0.53 0.8064 0.9972 1691722 ChemDiv1_027487 Clc1cccc(c1)N2CCN(CC2)c3ccc4nnnn4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B10 compound treatment 650999.0 193000.0 0.4 622042.0 160000.0 0.35 0.526 0.9977 1982757 ChemDiv1_027488 c1[nH]c2ccccc2c1c3nnc4ccc5ccccc5n34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B11 compound treatment 724368.0 266000.0 0.55 686481.0 225000.0 0.49 0.7317 0.9982 1982758 ChemDiv1_027489 COc1ccc(c2nnc3ccc4ccccc4n23)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B12 compound treatment 730260.0 272000.0 0.56 687355.0 225000.0 0.49 0.7417 0.9976 1612770 ChemDiv1_027490 COc1ccc2SC(=c3sc(=C4N(C)C(=S)N(C)C4=O)n(Cc5ccccc5)c3=O)N(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B13 compound treatment 733262.0 275000.0 0.57 670852.0 209000.0 0.45 0.7208 0.9937 1291805 ChemDiv1_027491 CCOc1ccc(CC2=NCCc3cc(OCC)c(OCC)cc23)cc1OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B14 compound treatment 723076.0 265000.0 0.55 689442.0 227000.0 0.49 0.7344 0.9987 1982759 ChemDiv1_027492 O=C(NNc1ccccc1)C(=O)NN=C2CSc3sc(=O)sc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B15 compound treatment 756649.0 298000.0 0.62 719105.0 257000.0 0.56 0.8288 0.9987 1982760 ChemDiv1_027493 CCOC(=O)C1=NN(C2C1C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B16 compound treatment 714537.0 256000.0 0.53 702450.0 240000.0 0.52 0.7418 1.0 1661820 ChemDiv1_027494 CC1CCC(=C(C#N)c2nc(cs2)c3ccc(Br)cc3)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B17 compound treatment 755588.0 297000.0 0.61 723130.0 261000.0 0.57 0.8334 0.9992 1982761 ChemDiv1_027495 Fc1cccc(c1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B18 compound treatment 697032.0 239000.0 0.49 685685.0 224000.0 0.48 0.6906 1.0 1633443 ChemDiv1_027496 COc1ccc2SC(=c3sc(=C4SC(=S)N(C5CCCCC5)C4=O)n(C6CCCCC6)c3=O)N(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B19 compound treatment 711702.0 253000.0 0.52 682866.0 221000.0 0.48 0.7077 0.999 1982762 ChemDiv1_027497 COc1ccc(NC(=S)N2C3CCN(C)CC3c4cc(C)ccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B20 compound treatment 707657.0 249000.0 0.51 679979.0 218000.0 0.47 0.6974 0.9991 1381403 ChemDiv1_027498 COc1ccc(cc1)c2csc(=Nc3ccccn3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B21 compound treatment 671347.0 213000.0 0.44 708270.0 246000.0 0.53 0.6877 0.9954 1342117 ChemDiv1_027499 Clc1ccc(cc1)c2nc([nH]c2c3ccccc3)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B22 compound treatment 639931.0 181000.0 0.37 647006.0 185000.0 0.4 0.5481 0.9994 1982763 ChemDiv1_027500 CCOC(=O)C(NC(=O)c1ccccc1F)(Nc2sc3CCCCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B23 mock treatment 668566.0 210000.0 0.43 659308.0 197000.0 0.43 0.6087 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 B24 mock treatment 205810.0 -253000.0 -0.52 238722.0 -223000.0 -0.48 -0.7105 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C01 compound treatment 633118.0 175000.0 0.36 600331.0 138000.0 0.3 0.4667 0.9957 1982764 ChemDiv1_027501 OC1(C2CCCCCC2=NN1C(=O)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C02 compound treatment 633072.0 175000.0 0.36 606980.0 145000.0 0.31 0.4768 0.9976 1982765 ChemDiv1_027502 Fc1ccccc1CSc2nnc(c3ccco3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C03 compound treatment 704934.0 246000.0 0.51 736569.0 275000.0 0.59 0.78 0.997 1982766 ChemDiv1_027503 CSc1cccc(c1)[C@H]2[C@@H](N3C=Cc4ccccc4[C@H]3C2(C#N)C#N)C(=O)C5(CC6CC7CC(C6)C5)C7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C04 compound treatment 664752.0 206000.0 0.43 644560.0 183000.0 0.4 0.5806 0.9993 1982767 ChemDiv1_027504 CCN(CC)c1ccc(/C=C/C23NC(=O)CCN3c4ccc(C)cc4C2(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C05 compound treatment 853634.0 395000.0 0.82 834482.0 373000.0 0.81 1.1469 1.0 1599090 ChemDiv1_027505 COc1ccccc1C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C06 compound treatment 654927.0 196000.0 0.41 603288.0 141000.0 0.31 0.5031 0.9903 1982768 ChemDiv1_027506 CC1(C)c2ccccc2N3CCC(=O)NC31/C=C/c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C07 compound treatment 705765.0 247000.0 0.51 676918.0 215000.0 0.47 0.69 0.9989 1982769 ChemDiv1_027507 COc1ccc(cc1)N2C(=O)C3ON(C4SC(=S)N(C)C4(C)C)C(C3C2=O)c5ccc(cc5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C08 compound treatment 701485.0 243000.0 0.5 683195.0 221000.0 0.48 0.6933 0.9997 1982770 ChemDiv1_027508 Fc1ccc(N=c2scc(c3ccc(F)cc3)n2CCc4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C09 compound treatment 729608.0 271000.0 0.56 710858.0 249000.0 0.54 0.7767 0.9998 1982771 ChemDiv1_027509 COc1ccc(cc1)N2C(=O)C3ON(C4SC(=S)N(C)C4(C)C)C(C3C2=O)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C10 compound treatment 688670.0 230000.0 0.48 625713.0 164000.0 0.35 0.5866 0.9896 1357999 ChemDiv1_027510 O=C1CC(C2COC1O2)n3nnn(c4ccccc4)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C11 compound treatment 728490.0 270000.0 0.56 706021.0 244000.0 0.53 0.7677 0.9996 1982772 ChemDiv1_027511 CCC(=O)NC1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C12 compound treatment 1037473.0 579000.0 1.2 998084.0 536000.0 1.16 1.6657 0.9999 1480242 ChemDiv1_027512 Cc1ccc(cc1)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C13 compound treatment 684091.0 226000.0 0.47 665826.0 204000.0 0.44 0.6413 0.9996 1982773 ChemDiv1_027513 CC(=O)C1=NN(C(N1C(C)(C)C)c2cccs2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C14 compound treatment 720254.0 262000.0 0.54 713465.0 251000.0 0.54 0.767 1.0 1982774 ChemDiv1_027514 CC1CCCCC21NN(C(=S)N2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C15 compound treatment 743458.0 285000.0 0.59 749264.0 287000.0 0.62 0.8557 0.9996 1553125 ChemDiv1_027515 CC1CC(=O)NC2(C)N1c3ccccc3C2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C16 compound treatment 731040.0 273000.0 0.56 717155.0 255000.0 0.55 0.7884 1.0 1982775 ChemDiv1_027516 Cc1cn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)[nH]c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C17 compound treatment 744662.0 286000.0 0.59 687478.0 226000.0 0.49 0.7629 0.9955 1982776 ChemDiv1_027517 OC(=O)CCc1nn2cc(nc2[nH]c1=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C18 compound treatment 696071.0 238000.0 0.49 682224.0 220000.0 0.48 0.6839 0.9999 1982777 ChemDiv1_027518 Ic1ccc(/N=C/2\NC3(CCCCC3)Cc4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C19 compound treatment 697913.0 239000.0 0.49 706781.0 245000.0 0.53 0.7242 0.9994 1982778 ChemDiv1_027519 CCCCC1(C)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C20 compound treatment 696941.0 238000.0 0.49 671618.0 210000.0 0.45 0.669 0.9992 1982779 ChemDiv1_027520 CCCOC(=O)c1ccc(cc1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C21 compound treatment 691205.0 233000.0 0.48 701057.0 239000.0 0.52 0.7056 0.9993 1982780 ChemDiv1_027521 BrC1(C2C(C(=O)N(Cc3cccnc3)C2=O)C4(Br)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C22 compound treatment 646529.0 188000.0 0.39 784748.0 323000.0 0.7 0.7685 0.9616 1982781 ChemDiv1_027522 CC(C)c1ccc(/C=C/C23NC(=O)CCN3c4ccccc4C2(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C23 mock treatment 651769.0 193000.0 0.4 663679.0 202000.0 0.44 0.5909 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 C24 mock treatment 233403.0 -225000.0 -0.46 227727.0 -234000.0 -0.51 -0.687 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D01 compound treatment 655546.0 197000.0 0.41 598904.0 137000.0 0.3 0.4973 0.9879 1541231 ChemDiv1_027523 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(C2c3ccccc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D02 compound treatment 674571.0 216000.0 0.45 629599.0 168000.0 0.36 0.572 0.9947 1982782 ChemDiv1_027524 S=c1sc2SCC(=NNc3ccccc3)CSc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D03 compound treatment 702395.0 244000.0 0.5 744163.0 282000.0 0.61 0.788 0.9954 1342692 ChemDiv1_027525 OC1=C(C(N(C1=O)c2ccccc2)c3ccc4OCOc4c3)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D04 compound treatment 671357.0 213000.0 0.44 644269.0 182000.0 0.39 0.5898 0.9986 1645633 ChemDiv1_027526 C=CCSc1nnc2c3ccccc3n(CCc4ccccc4)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D05 compound treatment 699822.0 241000.0 0.5 668983.0 207000.0 0.45 0.6691 0.9986 1982783 ChemDiv1_027527 Fc1ccc(/N=C/2\NC3(CCCCC3)Cc4ccccc24)cc1F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D06 compound treatment 672854.0 214000.0 0.44 648236.0 186000.0 0.4 0.598 0.9989 1982784 ChemDiv1_027528 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C(C)C)c3ccccc23)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D07 compound treatment 729786.0 271000.0 0.56 681251.0 219000.0 0.47 0.7317 0.9966 1982785 ChemDiv1_027529 O=C(N1N=C2N(C1N3CCCCC3)S(=O)(=O)c4ccccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D08 compound treatment 807007.0 349000.0 0.72 792266.0 330000.0 0.71 1.0143 1.0 1634808 ChemDiv1_027530 Cc1ccc(cc1)C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D09 compound treatment 742160.0 284000.0 0.59 721497.0 260000.0 0.56 0.8113 0.9998 1656651 ChemDiv1_027531 C1CN(CCN1c2ccccc2)c3ccc4nnnn4n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D10 compound treatment 725403.0 267000.0 0.55 682157.0 220000.0 0.48 0.7266 0.9974 1982786 ChemDiv1_027532 COc1c(Cl)cc(Cl)cc1c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D11 compound treatment 740793.0 282000.0 0.58 719990.0 258000.0 0.56 0.807 0.9998 1982787 ChemDiv1_027533 COc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D12 compound treatment 718078.0 260000.0 0.54 677384.0 215000.0 0.47 0.7086 0.9976 1386278 ChemDiv1_027534 COc1ccc2SC(=c3sc(=C4N(C(=S)N(C)C4=O)c5ccccc5)n(C6CCCCC6)c3=O)N(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D13 compound treatment 751610.0 293000.0 0.61 690261.0 228000.0 0.49 0.7773 0.9949 1615525 ChemDiv1_027535 Cn1c(=O)[nH]c(=O)c2n(Cc3ccccc3)cnc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D14 compound treatment 745796.0 287000.0 0.59 715294.0 253000.0 0.55 0.8071 0.9992 1982788 ChemDiv1_027536 O=C(NN=C1CSc2sc(=O)sc2SC1)c3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D15 compound treatment 758212.0 300000.0 0.62 755009.0 293000.0 0.63 0.886 0.9999 1300991 ChemDiv1_027537 CCCCC1(CC(=O)Nc2ccc(F)cc2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D16 compound treatment 887157.0 429000.0 0.88 901731.0 440000.0 0.95 1.2988 0.9993 1982789 ChemDiv1_027538 Fc1ccccc1C2N(C(=O)C3=C2/C(=C/c4ccccc4)/C(=O)N3c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D17 compound treatment 762646.0 304000.0 0.63 718083.0 256000.0 0.55 0.836 0.9981 1945748 ChemDiv1_027539 FC(F)(F)c1cccc(c1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D18 compound treatment 721773.0 263000.0 0.54 722859.0 261000.0 0.56 0.7836 0.9998 1982790 ChemDiv1_027540 CN1C(=c2sc(=C3SC(=S)N(C4CCCCC4)C3=O)n(C5CCCCC5)c2=O)Sc6ccccc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D19 compound treatment 745427.0 287000.0 0.59 681203.0 219000.0 0.47 0.7544 0.9939 1982791 ChemDiv1_027541 CCn1c2ccccc2c3nnc(SCC#C)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D20 compound treatment 755588.0 297000.0 0.61 742760.0 281000.0 0.61 0.8635 1.0 1982792 ChemDiv1_027542 Brc1ccc(cc1)C2N(C(=O)C3=C2/C(=C/c4ccc5OCOc5c4)/C(=O)N3c6ccccc6)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D21 compound treatment 726817.0 268000.0 0.55 728276.0 266000.0 0.58 0.7993 0.9998 1686816 ChemDiv1_027543 Brc1ccc(cc1)N2C(=O)C3C(N4CCCN4C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D22 compound treatment 686280.0 228000.0 0.47 662044.0 200000.0 0.43 0.6388 0.9992 1982793 ChemDiv1_027544 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccccc4)/Oc3c(NC=O)cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D23 mock treatment 679975.0 222000.0 0.46 706497.0 245000.0 0.53 0.6976 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 D24 mock treatment 232554.0 -226000.0 -0.47 210061.0 -252000.0 -0.55 -0.7153 -0.997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E01 compound treatment 621378.0 163000.0 0.34 587493.0 126000.0 0.27 0.4299 0.9944 1982794 ChemDiv1_027545 CC1Sc2sc(=O)sc2SC(C)(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E02 compound treatment 666672.0 208000.0 0.43 626749.0 165000.0 0.36 0.5561 0.9957 1910341 ChemDiv1_027546 Nc1c(sc2sc(C(=O)c3ccccc3)c(N)c12)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E03 compound treatment 678402.0 220000.0 0.45 684732.0 223000.0 0.48 0.662 0.9995 1425334 ChemDiv1_027547 Cc1ccc(NC(=O)C2CCCN2C(=O)Oc3ccccc3)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E04 compound treatment 679635.0 221000.0 0.46 643541.0 182000.0 0.39 0.6007 0.9972 1164116 ChemDiv1_027548 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E05 compound treatment 698206.0 240000.0 0.49 700522.0 239000.0 0.52 0.715 0.9998 1303168 ChemDiv1_027549 Cc1c(N(CC(=O)O)S(=O)(=O)c2ccccc2)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E06 compound treatment 685140.0 227000.0 0.47 673052.0 211000.0 0.46 0.6539 0.9999 1982795 ChemDiv1_027550 CCOC(=O)C1=NN(C2C1C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E07 compound treatment 708973.0 251000.0 0.52 673563.0 212000.0 0.46 0.6895 0.9982 1982796 ChemDiv1_027551 Cc1nnc2SCC(=Nn12)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E08 compound treatment 700950.0 242000.0 0.5 690400.0 228000.0 0.49 0.7036 1.0 1982797 ChemDiv1_027552 COC(=O)C1(O)N(C(=O)C(=C1C(=O)c2ccc(Br)cc2)O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E09 compound treatment 704969.0 247000.0 0.51 709238.0 247000.0 0.54 0.7383 0.9997 1982798 ChemDiv1_027553 CN1C(=S)SC(N2OC3C(C2c4ccccc4)C(=O)N(C3=O)c5ccccc5)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E10 compound treatment 691270.0 233000.0 0.48 681921.0 220000.0 0.48 0.6765 1.0 1368059 ChemDiv1_027554 O=C1CC(C2COC1O2)n3nc(c4ccccc4)n(c5ccccc5)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E11 compound treatment 738656.0 280000.0 0.58 713575.0 252000.0 0.54 0.7941 0.9995 1982799 ChemDiv1_027555 CNC1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E12 compound treatment 908420.0 450000.0 0.93 869462.0 407000.0 0.88 1.2804 0.9997 1982800 ChemDiv1_027556 NC1=C(C#N)C2=CCCCC2C(c3cccc(F)c3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E13 compound treatment 791344.0 333000.0 0.69 781444.0 319000.0 0.69 0.9748 1.0 1982801 ChemDiv1_027557 CC(=O)C1=NN(C(N1c2ccccc2)c3cccs3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E14 compound treatment 719711.0 261000.0 0.54 675392.0 213000.0 0.46 0.708 0.997 1131990 ChemDiv1_027558 CCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(c3ccccc3)C2(O)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E15 compound treatment 592848.0 134000.0 0.28 479141.0 17200.0 0.04 0.2224 0.7947 1982802 ChemDiv1_027559 CC1CN2c3ccccc3C(C)(C)C2(NC1=O)/C=C/c4ccc(cc4)N(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E16 compound treatment 729360.0 271000.0 0.56 661876.0 200000.0 0.43 0.7014 0.992 1982803 ChemDiv1_027560 CCC(=O)N1C2CCN(C)CC2c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E17 compound treatment 745842.0 287000.0 0.59 731478.0 270000.0 0.58 0.832 1.0 1693572 ChemDiv1_027561 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccc(Br)cc4)c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E18 compound treatment 699660.0 241000.0 0.5 706172.0 244000.0 0.53 0.7258 0.9996 1982804 ChemDiv1_027562 Cc1ccc(cc1)C(=O)Sc2sc(=S)sc2SC(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E19 compound treatment 705196.0 247000.0 0.51 696568.0 235000.0 0.51 0.7192 1.0 1718787 ChemDiv1_027563 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc5ccccc5[nH]4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E20 compound treatment 717795.0 259000.0 0.54 685340.0 223000.0 0.48 0.7204 0.9987 1373568 ChemDiv1_027564 CC1(C2C(C(=O)N(C2=O)c3cccc(Br)c3)C4(C=O)c5ccccc51)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E21 compound treatment 706973.0 249000.0 0.51 707673.0 246000.0 0.53 0.7388 0.9998 1982805 ChemDiv1_027565 Oc1ccc(Br)cc1CP(=O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E22 compound treatment 679530.0 221000.0 0.46 679668.0 218000.0 0.47 0.6559 0.9999 1243542 ChemDiv1_027566 CC(C)c1ccc(cc1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E23 mock treatment 676495.0 218000.0 0.45 679171.0 217000.0 0.47 0.6507 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 E24 mock treatment 276692.0 -182000.0 -0.38 190437.0 -272000.0 -0.59 -0.6809 -0.9765 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F01 compound treatment 635712.0 177000.0 0.37 606175.0 144000.0 0.31 0.4794 0.9969 1147290 ChemDiv1_027567 CCN1C2NC(=O)N(CC)C2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F02 compound treatment 652871.0 194000.0 0.4 612870.0 151000.0 0.33 0.5147 0.9948 1982806 ChemDiv1_027568 Oc1ccc(cc1c2nc(c([nH]2)c3ccccc3)c4ccc(Cl)cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F03 compound treatment 708848.0 250000.0 0.52 689930.0 228000.0 0.49 0.7144 0.9997 1982807 ChemDiv1_027569 Clc1cccc(Cl)c1c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F04 compound treatment 684416.0 226000.0 0.47 675071.0 213000.0 0.46 0.656 1.0 1982808 ChemDiv1_027570 CC(=O)Oc1ccc(c(OC(=O)C)c1)C2(C)CC(C)(C)NC(=S)N2c3cccc(c3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F05 compound treatment 723526.0 265000.0 0.55 715612.0 254000.0 0.55 0.7751 1.0 1982809 ChemDiv1_027571 CC(=O)C1=C(O)C(=O)N(C1c2ccc3OCOc3c2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F06 compound treatment 706912.0 248000.0 0.51 657524.0 196000.0 0.42 0.662 0.9954 1982810 ChemDiv1_027572 CCOC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C(C)C)c3ccc(OC)cc23)S1)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F07 compound treatment 748283.0 290000.0 0.6 692137.0 230000.0 0.5 0.7753 0.9959 1982811 ChemDiv1_027573 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F08 compound treatment 737487.0 279000.0 0.58 696966.0 235000.0 0.51 0.7669 0.9981 1638269 ChemDiv1_027574 COc1cc(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)ccc1OCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F09 compound treatment 803038.0 345000.0 0.71 779607.0 318000.0 0.69 0.9891 0.9999 1323307 ChemDiv1_027575 O=C(COC(=O)CSc1nc(cc(n1)c2ccccc2)c3ccccc3)NC4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F10 compound treatment 714161.0 256000.0 0.53 755866.0 294000.0 0.64 0.823 0.9957 1943249 ChemDiv1_027576 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(F)cc5)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F11 compound treatment 748317.0 290000.0 0.6 680243.0 218000.0 0.47 0.7572 0.9932 1418933 ChemDiv1_027577 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)C4(CC5CC6CC(C5)C4)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F12 compound treatment 737876.0 279000.0 0.58 705216.0 243000.0 0.53 0.7801 0.999 1982812 ChemDiv1_027578 CCN1C(=O)/C(=C/2\Sc3ccc(Cl)cc3N2C4CCCCC4)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F13 compound treatment 832824.0 374000.0 0.77 713491.0 252000.0 0.54 0.9314 0.9853 1706536 ChemDiv1_027579 COc1ccc(cc1)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F14 compound treatment 760220.0 302000.0 0.62 712212.0 250000.0 0.54 0.8235 0.9976 1142145 ChemDiv1_027580 CN(C)c1ccc(cc1)C2CC(Nc3ncnn23)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F15 compound treatment 756667.0 298000.0 0.62 760764.0 299000.0 0.65 0.8926 0.9997 1779829 ChemDiv1_027581 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4c[nH]nc4c5ccccc5)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F16 compound treatment 756945.0 298000.0 0.62 772363.0 310000.0 0.67 0.9107 0.9991 1982813 ChemDiv1_027582 CCOC(=O)NC(Nc1ccccn1)(C(=O)OCC)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F17 compound treatment 762405.0 304000.0 0.63 712832.0 251000.0 0.54 0.8276 0.9974 1945703 ChemDiv1_027583 FC(F)(F)c1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F18 compound treatment 762357.0 304000.0 0.63 763999.0 302000.0 0.65 0.9058 0.9998 1982814 ChemDiv1_027584 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(OC(=O)c5ccc(Cl)cc5)cc4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F19 compound treatment 739912.0 281000.0 0.58 751581.0 290000.0 0.63 0.8541 0.9993 1982815 ChemDiv1_027585 CN1C(=O)N(C)C2(NC(=N)NNC12c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F20 compound treatment 745266.0 287000.0 0.59 707331.0 245000.0 0.53 0.7942 0.9985 1982816 ChemDiv1_027586 CC1CCC(CC1)(NC(=O)C)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F21 compound treatment 760363.0 302000.0 0.62 707865.0 246000.0 0.53 0.817 0.9969 1982817 ChemDiv1_027587 S(c1ccccc1)c2ccc(cc2)c3nc([nH]c3c4ccccc4)c5cccc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F22 compound treatment 676187.0 218000.0 0.45 666433.0 204000.0 0.44 0.6307 1.0 1424831 ChemDiv1_027588 CC1=C(C(CC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F23 mock treatment 687150.0 229000.0 0.47 675425.0 213000.0 0.46 0.6605 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 F24 mock treatment 221653.0 -237000.0 -0.49 186301.0 -276000.0 -0.6 -0.7676 -0.9951 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G01 compound treatment 625150.0 167000.0 0.34 585230.0 123000.0 0.27 0.432 0.9921 1139570 ChemDiv1_027589 C1CN(CCO1)c2nc(nc3c4ccccc4oc23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G02 compound treatment 671744.0 213000.0 0.44 645798.0 184000.0 0.4 0.5927 0.9987 1742226 ChemDiv1_027590 CCCS(=O)(=O)c1c(C(=O)c2ccc(Br)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G03 compound treatment 688691.0 230000.0 0.48 677854.0 216000.0 0.47 0.6665 1.0 1611552 ChemDiv1_027591 COc1ccc(cc1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G04 compound treatment 684644.0 226000.0 0.47 648964.0 187000.0 0.4 0.6163 0.9975 1153906 ChemDiv1_027592 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G05 compound treatment 701714.0 243000.0 0.5 705897.0 244000.0 0.53 0.7284 0.9997 1592486 ChemDiv1_027593 COC(=O)c1nnn(c1CN2CCCC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G06 compound treatment 679826.0 221000.0 0.46 684581.0 223000.0 0.48 0.6638 0.9997 1982818 ChemDiv1_027594 O=C1CSc2sc(=O)sc2S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G07 compound treatment 713586.0 255000.0 0.53 711041.0 249000.0 0.54 0.7536 0.9999 1982819 ChemDiv1_027595 [O-][N+](=O)c1ccccc1SC2CC3C(C2Cl)c4cc(Cl)ccc4NC3c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G08 compound treatment 696780.0 238000.0 0.49 705588.0 244000.0 0.53 0.7207 0.9994 1776016 ChemDiv1_027596 COc1ccc(cc1Cl)c2ccc(o2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CC(C)(C)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G09 compound treatment 750908.0 292000.0 0.6 700273.0 238000.0 0.52 0.7916 0.9969 1434475 ChemDiv1_027597 Nc1nc(=O)n(cc1Br)C2OC(CO)C(O)C2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G10 compound treatment 722183.0 264000.0 0.54 678541.0 217000.0 0.47 0.7164 0.9972 1255967 ChemDiv1_027598 Clc1ccccc1c2nn(C3CC(=O)C4OCC3O4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G11 compound treatment 713961.0 256000.0 0.53 675969.0 214000.0 0.46 0.7005 0.9979 1982820 ChemDiv1_027599 CCC1(C)Cc2ccccc2/C(=C/3\C(=NN(C3=O)c4ccccc4)C)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G12 compound treatment 843075.0 385000.0 0.79 820259.0 358000.0 0.78 1.1098 0.9999 1428150 ChemDiv1_027600 NC1=C(C#N)C2=CCCCC2C(c3ccccc3I)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G13 compound treatment 783927.0 325000.0 0.67 748654.0 287000.0 0.62 0.9138 0.9992 1982821 ChemDiv1_027601 COc1ccc(cc1)N2C(N(N=C2C(=O)C)c3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G14 compound treatment 759227.0 301000.0 0.62 703653.0 242000.0 0.52 0.8089 0.9964 1439963 ChemDiv1_027602 COC(=O)C1(Nc2c(Cl)cccc2Cl)N(C(=O)C(=C1C(=O)c3ccc(C)cc3)O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G15 compound treatment 746229.0 288000.0 0.59 718414.0 256000.0 0.56 0.8125 0.9994 1278751 ChemDiv1_027603 OC12NC(=O)N(c3ccccc3)C2(O)c4ccccc4C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G16 compound treatment 727584.0 269000.0 0.56 683858.0 222000.0 0.48 0.7324 0.9974 1349328 ChemDiv1_027604 CCCCC1(CC(=O)OC)C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G17 compound treatment 763376.0 305000.0 0.63 719319.0 257000.0 0.56 0.8389 0.9981 1340686 ChemDiv1_027605 CN1C(=O)N(C)C2(N=c3sc(=Cc4ccccc4F)c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G18 compound treatment 703285.0 245000.0 0.51 698011.0 236000.0 0.51 0.7186 1.0 1982822 ChemDiv1_027606 OC1=C(C(N(C1=O)c2cccc(c2)C(F)(F)F)c3ccccc3F)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G19 compound treatment 750541.0 292000.0 0.6 721660.0 260000.0 0.56 0.8238 0.9994 1292777 ChemDiv1_027607 Nc1nonc1n2nnc(C(=O)O)c2CN3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G20 compound treatment 728645.0 270000.0 0.56 696317.0 234000.0 0.51 0.753 0.9989 1982823 ChemDiv1_027608 O=C(N/N=C/c1ccc(Sc2nnc(c3ccccc3)n2c4ccccc4)o1)c5ccncc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G21 compound treatment 722118.0 264000.0 0.54 680809.0 219000.0 0.47 0.7198 0.9976 1297450 ChemDiv1_027609 CC1(O)N(CCC#N)C(=O)OC21CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G22 compound treatment 706337.0 248000.0 0.51 700253.0 238000.0 0.52 0.7265 1.0 1982824 ChemDiv1_027610 CCn1c(=O)c(=C/C=C/2\SC(=C(N2C)c3ccccc3)c4ccccc4)sc1=C5C(=NN(C5=O)c6ccccc6)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G23 mock treatment 684863.0 226000.0 0.47 671351.0 209000.0 0.45 0.6509 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 G24 mock treatment 205108.0 -253000.0 -0.52 177641.0 -284000.0 -0.62 -0.805 -0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H01 compound treatment 634075.0 176000.0 0.36 597081.0 135000.0 0.29 0.4631 0.9943 1982825 ChemDiv1_027611 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4ccc5ccccc5c4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H02 compound treatment 648558.0 190000.0 0.39 604085.0 142000.0 0.31 0.495 0.9927 1982826 ChemDiv1_027612 CC1(C)c2ccccc2N3CC(=O)NC31/C=C/c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H03 compound treatment 677945.0 219000.0 0.45 671585.0 210000.0 0.45 0.6412 1.0 1982827 ChemDiv1_027613 Clc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H04 compound treatment 671960.0 214000.0 0.44 638893.0 177000.0 0.38 0.5824 0.9975 1325791 ChemDiv1_027614 CCN(CC)c1ccc(cc1)C2CC(C)NC(=S)N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H05 compound treatment 708645.0 250000.0 0.52 694953.0 233000.0 0.5 0.7218 0.9999 1594031 ChemDiv1_027615 CCCCC1(CC(=O)Nc2ccc(CC)cc2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H06 compound treatment 684752.0 226000.0 0.47 654643.0 193000.0 0.42 0.6252 0.9984 1982828 ChemDiv1_027616 CCCCC(=O)N1c2ccc(OC)cc2C(=C3SC(=C(S3)C(=O)OCC)C(=O)OCC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H07 compound treatment 829588.0 371000.0 0.77 755950.0 294000.0 0.64 0.9917 0.9957 1982829 ChemDiv1_027617 CN1C(=O)/C(=C\2/Sc3ccccc3N2CCCS(=O)(=O)O)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H08 compound treatment 704635.0 246000.0 0.51 686363.0 224000.0 0.49 0.7028 0.9997 1290873 ChemDiv1_027618 C1CCC(CC1)Nc2nc(nc3c4ccccc4oc23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H09 compound treatment 726112.0 268000.0 0.55 677787.0 216000.0 0.47 0.721 0.9965 1982830 ChemDiv1_027619 CCOC(=O)C1=NNC2(C)C1C(=O)N(C2=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H10 compound treatment 780919.0 322000.0 0.67 711351.0 249000.0 0.54 0.8524 0.9946 1943246 ChemDiv1_027620 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5cc(ccc5Cl)C(F)(F)F)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H11 compound treatment 724177.0 266000.0 0.55 724830.0 263000.0 0.57 0.7902 0.9998 1982831 ChemDiv1_027621 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H12 compound treatment 704655.0 246000.0 0.51 684713.0 223000.0 0.48 0.7003 0.9997 1127503 ChemDiv1_027622 COc1cc(ccc1O)C2N(CCN2S(=O)(=O)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H13 compound treatment 703566.0 245000.0 0.51 703576.0 242000.0 0.52 0.7275 0.9999 1663895 ChemDiv1_027623 O=C1CC(C2COC1O2)n3nnn(c4cccc5ccccc45)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H14 compound treatment 728380.0 270000.0 0.56 736238.0 274000.0 0.59 0.8138 0.9995 1228268 ChemDiv1_027624 C1C(Nc2ncnn2C1c3ccco3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H15 compound treatment 731328.0 273000.0 0.56 712743.0 251000.0 0.54 0.7821 0.9998 1281697 ChemDiv1_027625 CN(C)CCn1c-2c(CCCn3cnnc23)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H16 compound treatment 712743.0 254000.0 0.52 728914.0 267000.0 0.58 0.7797 0.9989 1625508 ChemDiv1_027626 CCN1C(=c2sc(=C3C(=O)c4ccccc4C3=O)n(CC)c2=O)C=Cc5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H17 compound treatment 715560.0 257000.0 0.53 722789.0 261000.0 0.56 0.7745 0.9995 1982832 ChemDiv1_027627 Fc1cccc(c1)c2nnc3ccc4cc(ccc4n23)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H18 compound treatment 691904.0 233000.0 0.48 677578.0 216000.0 0.47 0.6707 0.9999 1982833 ChemDiv1_027628 NS(=O)(=O)c1ccc(CCn2c(csc2=Nc3ccc(OC(F)(F)F)cc3)c4ccc(Cl)s4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H19 compound treatment 710005.0 252000.0 0.52 689024.0 227000.0 0.49 0.7147 0.9996 1982834 ChemDiv1_027629 [O-][N+](=O)c1ccc2O/C(=C/COc3ccc4ccccc4c3Br)/C(N5CCOCC5)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H20 compound treatment 690152.0 232000.0 0.48 699781.0 238000.0 0.51 0.7022 0.9993 1982835 ChemDiv1_027630 CCOc1cccc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C(C)(C)N(C(=O)Cc4ccc(F)cc4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H21 compound treatment 718511.0 260000.0 0.54 691374.0 229000.0 0.5 0.7307 0.9992 1982836 ChemDiv1_027631 O=C(COC(=O)CSc1nc(cc(n1)c2ccccc2)c3ccccc3)NCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H22 compound treatment 682456.0 224000.0 0.46 702961.0 241000.0 0.52 0.6958 0.9982 1432728 ChemDiv1_027632 CCOC(=O)c1nc2cc3C(=CC(C)n3c(C)c2c1C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H23 mock treatment 677018.0 219000.0 0.45 695379.0 233000.0 0.51 0.6763 0.9984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 H24 mock treatment 232554.0 -226000.0 -0.47 193725.0 -268000.0 -0.58 -0.7403 -0.9941 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I01 compound treatment 635511.0 177000.0 0.37 581195.0 119000.0 0.26 0.4409 0.9855 1448220 ChemDiv1_027633 O=C(CSCC(=O)N1CCCc2ccccc12)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I02 compound treatment 652938.0 194000.0 0.4 617221.0 155000.0 0.34 0.5215 0.9961 1982837 ChemDiv1_027634 CN1C(NC(=O)NCCO)C(NC(=O)NCCO)N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I03 compound treatment 699020.0 241000.0 0.5 665458.0 203000.0 0.44 0.6626 0.9982 1982838 ChemDiv1_027635 COCC(=O)NC1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I04 compound treatment 696468.0 238000.0 0.49 662681.0 201000.0 0.43 0.6546 0.9981 1328807 ChemDiv1_027636 Cc1cc(C)cc(NC(=O)C2CC(O)CN2C(=O)Oc3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I05 compound treatment 719991.0 262000.0 0.54 698020.0 236000.0 0.51 0.743 0.9996 1148040 ChemDiv1_027637 Fc1ccccc1C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I06 compound treatment 694748.0 236000.0 0.49 667244.0 205000.0 0.44 0.6591 0.9989 1982839 ChemDiv1_027638 OC1CSc2sc(=S)sc2SC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I07 compound treatment 720937.0 262000.0 0.54 686817.0 225000.0 0.49 0.7273 0.9986 1982840 ChemDiv1_027639 Clc1cccc(c1)n2nnnc2C3(CCCC3)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I08 compound treatment 732494.0 274000.0 0.57 673832.0 212000.0 0.46 0.7243 0.9946 1572344 ChemDiv1_027640 COc1ccc(cc1OC)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I09 compound treatment 722151.0 264000.0 0.54 697823.0 236000.0 0.51 0.7459 0.9995 1686012 ChemDiv1_027641 C=C1N(CCc2ccccc2)C(=O)OC31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I10 compound treatment 708530.0 250000.0 0.52 656799.0 195000.0 0.42 0.6632 0.995 1266070 ChemDiv1_027642 COc1ccc(cc1OC)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I11 compound treatment 740617.0 282000.0 0.58 691151.0 229000.0 0.5 0.7626 0.9968 1982841 ChemDiv1_027643 CN(C)C1=NC(N=C(O1)c2ccco2)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I12 compound treatment 811760.0 353000.0 0.73 756774.0 295000.0 0.64 0.9669 0.9978 1448709 ChemDiv1_027644 NC1=C(C#N)C2=CCCCC2C(c3ccncc3)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I13 compound treatment 756121.0 298000.0 0.61 682871.0 221000.0 0.48 0.7726 0.9923 1634728 ChemDiv1_027645 O=C(CSc1nnc2c3ccccc3[nH]c2n1)NCC4CCCO4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I14 compound treatment 741311.0 283000.0 0.58 709885.0 248000.0 0.54 0.7923 0.9991 1119728 ChemDiv1_027646 COC(=O)C1(O)N(C(=O)C(=C1C(=O)c2ccc(OC)cc2)O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I15 compound treatment 771019.0 313000.0 0.65 724846.0 263000.0 0.57 0.8586 0.998 1982842 ChemDiv1_027647 Clc1ccc(cc1)N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I16 compound treatment 741539.0 283000.0 0.58 704871.0 243000.0 0.53 0.785 0.9986 1982843 ChemDiv1_027648 COc1ccc(NC2=CC(N(C2=O)c3ccc(OC)cc3)c4ccc(F)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I17 compound treatment 751588.0 293000.0 0.61 700976.0 239000.0 0.52 0.7937 0.997 1614636 ChemDiv1_027649 CN(C)c1ccc(cc1)C2N(CCN2C(=O)c3ccccc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I18 compound treatment 1043340.0 585000.0 1.21 1090695.0 629000.0 1.36 1.816 0.9982 1982844 ChemDiv1_027650 Cc1ccccc1NC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I19 compound treatment 736481.0 278000.0 0.57 683481.0 222000.0 0.48 0.7448 0.996 1982845 ChemDiv1_027651 CCNC1(CCC(C)CC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I20 compound treatment 710963.0 253000.0 0.52 684125.0 222000.0 0.48 0.7086 0.9992 1982846 ChemDiv1_027652 COc1ccc(CCn2c(csc2=Nc3ccccc3)c4ccc(C)c(C)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I21 compound treatment 739216.0 281000.0 0.58 692689.0 231000.0 0.5 0.7629 0.9972 1982847 ChemDiv1_027653 Nc1nonc1n2nnc(C(=O)N/N=C\C3CCC=CC3)c2CN4CCCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I22 compound treatment 692838.0 234000.0 0.48 697213.0 235000.0 0.51 0.7021 0.9997 1695758 ChemDiv1_027654 COc1ccc(c2nc3c([nH]2)c4ccccc4c5ccc(I)cc35)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I23 mock treatment 691131.0 233000.0 0.48 690849.0 229000.0 0.5 0.6899 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 I24 mock treatment 224481.0 -234000.0 -0.48 181034.0 -281000.0 -0.61 -0.7715 -0.9935 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J01 compound treatment 640858.0 182000.0 0.38 595489.0 134000.0 0.29 0.4706 0.9915 1724117 ChemDiv1_027655 Cn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J02 compound treatment 751733.0 293000.0 0.61 715628.0 254000.0 0.55 0.8163 0.9988 1982848 ChemDiv1_027656 CN(C)c1ccc(/C=C/C=C/C23NC(=O)CN3c4ccccc4C2(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J03 compound treatment 657050.0 199000.0 0.41 693097.0 231000.0 0.5 0.6436 0.9951 1212576 ChemDiv1_027657 CC1CCC2C3(C)COC(C)(C)OC3CCC2(C)C41CCC(C)(CO)O4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J04 compound treatment 675251.0 217000.0 0.45 688911.0 227000.0 0.49 0.6638 0.9989 1552445 ChemDiv1_027658 CCCN1C(=O)NC2(O)C(=O)c3ccccc3C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J05 compound treatment 710936.0 252000.0 0.52 698307.0 236000.0 0.51 0.7302 1.0 1161305 ChemDiv1_027659 CC1(O)N(CCN2C(=O)OC3(CCCCC3)C2(C)O)C(=O)OC41CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J06 compound treatment 669730.0 211000.0 0.44 664185.0 202000.0 0.44 0.6179 1.0 1982849 ChemDiv1_027660 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)C)c3c(C)cc(C)cc23)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J07 compound treatment 731517.0 273000.0 0.56 775186.0 313000.0 0.68 0.8779 0.9958 1982850 ChemDiv1_027661 NS(=O)(=O)c1ccc(CCn2c(csc2=Nc3ccccc3)c4ccc(cc4)C5CCCCC5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J08 compound treatment 701638.0 243000.0 0.5 710533.0 249000.0 0.54 0.7354 0.9994 1295902 ChemDiv1_027662 COCc1ccc2n3CCNC4CCCc(c43)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J09 compound treatment 739030.0 281000.0 0.58 717358.0 255000.0 0.55 0.8004 0.9997 1376006 ChemDiv1_027663 COc1ccc(OC)c(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J10 compound treatment 726292.0 268000.0 0.55 706994.0 245000.0 0.53 0.766 0.9998 1982851 ChemDiv1_027664 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccccc5C#N)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J11 compound treatment 728161.0 270000.0 0.56 710879.0 249000.0 0.54 0.7746 0.9999 1445727 ChemDiv1_027665 COc1ccc(cc1OC)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J12 compound treatment 724868.0 266000.0 0.55 699005.0 237000.0 0.51 0.7516 0.9994 1232729 ChemDiv1_027666 CC(C)OC(=O)c1nnn(c1CN2CCN(CC2)c3ccccn3)c4nonc4N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J13 compound treatment 746720.0 288000.0 0.6 704713.0 243000.0 0.53 0.7923 0.9981 1982852 ChemDiv1_027667 CCC1(CC)NN(C(=S)N1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J14 compound treatment 720845.0 262000.0 0.54 689221.0 227000.0 0.49 0.7308 0.9988 1612903 ChemDiv1_027668 Clc1cc(Cl)c2OC3(CCCCC3=Cc2c1)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J15 compound treatment 727815.0 269000.0 0.56 721449.0 259000.0 0.56 0.7903 1.0 1982853 ChemDiv1_027669 C(Oc1ccc(cc1)c2nnc3ccc4ccccc4n23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J16 compound treatment 717384.0 259000.0 0.53 706094.0 244000.0 0.53 0.7516 1.0 1586506 ChemDiv1_027670 COC(=O)CSc1sc(=O)sc1SCC#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J17 compound treatment 713496.0 255000.0 0.53 709551.0 248000.0 0.54 0.7512 1.0 1945262 ChemDiv1_027671 Fc1ccccc1c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J18 compound treatment 726621.0 268000.0 0.55 668251.0 206000.0 0.45 0.7071 0.9943 1982854 ChemDiv1_027672 COc1ccc(cc1F)c2csc(=Nc3ccc(OC(F)(F)F)cc3)n2CCc4ccc(cc4)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J19 compound treatment 721007.0 263000.0 0.54 741926.0 280000.0 0.61 0.8117 0.9985 1982855 ChemDiv1_027673 CCOC(=O)C(NC(=O)c1ccc(F)cc1)(Nc2nc3ccccc3nc2C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J20 compound treatment 730686.0 272000.0 0.56 725893.0 264000.0 0.57 0.8013 1.0 1317594 ChemDiv1_027674 CC(C)OC(=O)c1nnn(c1CN2CCC(CC2)C(=O)N)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J21 compound treatment 694603.0 236000.0 0.49 697525.0 236000.0 0.51 0.7052 0.9997 1982856 ChemDiv1_027675 CC1(CN2C(=O)N(C(=O)c3ccccc3)C(C)(C)C2=O)CC1(Cl)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J22 compound treatment 690266.0 232000.0 0.48 704543.0 243000.0 0.53 0.7096 0.9989 1982857 ChemDiv1_027676 CCOC(=O)C1(N=C(OC(=N1)c2ccccc2F)N(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J23 mock treatment 688887.0 230000.0 0.48 714548.0 253000.0 0.55 0.7229 0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 J24 mock treatment 217088.0 -241000.0 -0.5 190385.0 -272000.0 -0.59 -0.768 -0.9966 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K01 compound treatment 643743.0 185000.0 0.38 573612.0 112000.0 0.24 0.4413 0.9755 1198126 ChemDiv1_027677 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K02 compound treatment 1083384.0 625000.0 1.29 956564.0 495000.0 1.07 1.6691 0.9957 1982858 ChemDiv1_027678 COc1ccc(/C=C/C23NC(=O)CCN3c4ccccc4C2(C)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K03 compound treatment 688758.0 230000.0 0.48 670540.0 209000.0 0.45 0.6554 0.9997 1982859 ChemDiv1_027679 CNC1(CCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K04 compound treatment 679181.0 221000.0 0.46 635762.0 174000.0 0.38 0.5882 0.9955 1982860 ChemDiv1_027680 COc1ccc(CCn2c(csc2=Nc3ccccc3)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K05 compound treatment 700975.0 243000.0 0.5 672826.0 211000.0 0.46 0.6767 0.9989 1982861 ChemDiv1_027681 C=C1N(C2CCCCC2)C(=O)OC31CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K06 compound treatment 663372.0 205000.0 0.42 652862.0 191000.0 0.41 0.5913 0.9999 1982862 ChemDiv1_027682 S=c1sc2SCCCSc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K07 compound treatment 710251.0 252000.0 0.52 690079.0 228000.0 0.49 0.7166 0.9997 1982863 ChemDiv1_027683 CCN1C(=C)C2(CCCCC2)OC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K08 compound treatment 664391.0 206000.0 0.43 638179.0 176000.0 0.38 0.5703 0.9985 1775427 ChemDiv1_027684 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4cc(cc([N+](=O)[O-])c4O)[N+](=O)[O-])ccc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K09 compound treatment 727513.0 269000.0 0.56 674444.0 212000.0 0.46 0.7179 0.9956 1721862 ChemDiv1_027685 COc1cccc(C2N(CCN2c3ccc(C)cc3)c4ccc(C)cc4)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K10 compound treatment 722502.0 264000.0 0.55 669140.0 207000.0 0.45 0.7025 0.9953 1305635 ChemDiv1_027686 O=C1CC(C2COC1O2)n3nc(c4ccco4)n(c5ccccc5)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K11 compound treatment 775224.0 317000.0 0.65 649230.0 187000.0 0.41 0.749 0.9735 1982864 ChemDiv1_027687 CCC1(CC)Cc2ccccc2/C(=C/3\C(=NN(C3=O)c4ccccc4)C)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K12 compound treatment 705279.0 247000.0 0.51 678207.0 216000.0 0.47 0.6912 0.9991 1717168 ChemDiv1_027688 COC(=O)c1nnn(c1CN2CCN(C)CC2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K13 compound treatment 708385.0 250000.0 0.52 688022.0 226000.0 0.49 0.7108 0.9996 1982865 ChemDiv1_027689 Fc1ccc(cc1)C2=NC(N=C(O2)N3CCOCC3)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K14 compound treatment 711277.0 253000.0 0.52 680364.0 218000.0 0.47 0.7033 0.9988 1982866 ChemDiv1_027690 CC12CCCCC23NC(=O)CN3c4ccccc41 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K15 compound treatment 749241.0 291000.0 0.6 699002.0 237000.0 0.51 0.7872 0.9969 1982867 ChemDiv1_027691 CCOC(=O)C1(C)C=C(Nc2ccc(cc2)S(=O)(=O)N)C(=O)N1c3ccc(cc3)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K16 compound treatment 724336.0 266000.0 0.55 675529.0 214000.0 0.46 0.7149 0.9963 1743175 ChemDiv1_027692 Cc1cn(c2nc(oc2c3ccccc3)c4ccccc4)c(=O)nc1Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K17 compound treatment 723516.0 265000.0 0.55 689916.0 228000.0 0.49 0.7358 0.9987 1348495 ChemDiv1_027693 Oc1ccc(cc1Br)C2N(CCN2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K18 compound treatment 726582.0 268000.0 0.55 694793.0 233000.0 0.5 0.7477 0.9989 1982868 ChemDiv1_027694 O=Cc1ccc(Sc2nnc(c3ccccc3)n2c4ccccc4)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K19 compound treatment 736800.0 278000.0 0.57 693530.0 232000.0 0.5 0.7607 0.9977 1982869 ChemDiv1_027695 CN(C)C1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K20 compound treatment 712816.0 254000.0 0.53 703049.0 241000.0 0.52 0.7402 1.0 1169310 ChemDiv1_027696 Cc1ccc(cc1C)c2csc(=Nc3ccc(F)cc3)n2CCc4ccc(cc4)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K21 compound treatment 726249.0 268000.0 0.55 713396.0 251000.0 0.54 0.7757 1.0 1982870 ChemDiv1_027697 CC(O)[C@]12CC=CC[C@@H]2CC3C4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@@]31C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K22 compound treatment 680670.0 222000.0 0.46 686433.0 224000.0 0.49 0.6679 0.9996 1982871 ChemDiv1_027698 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4ccc(F)cc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K23 mock treatment 688218.0 230000.0 0.47 673723.0 212000.0 0.46 0.6595 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 K24 mock treatment 224795.0 -234000.0 -0.48 253068.0 -209000.0 -0.45 -0.6608 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L01 compound treatment 641881.0 183000.0 0.38 602177.0 140000.0 0.3 0.4823 0.994 1395056 ChemDiv1_027699 Clc1ccc(cc1)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L02 compound treatment 657797.0 199000.0 0.41 650640.0 189000.0 0.41 0.5797 1.0 1684468 ChemDiv1_027700 CC1(C)c2cc(Br)ccc2N3CCC(=O)NC31C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L03 compound treatment 683370.0 225000.0 0.46 679266.0 217000.0 0.47 0.6609 1.0 1982872 ChemDiv1_027701 COc1ccc(cc1F)c2csc(=Nc3ccccc3)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L04 compound treatment 672587.0 214000.0 0.44 667645.0 206000.0 0.45 0.6273 1.0 1181104 ChemDiv1_027702 O=C1CC(C2COC1O2)n3nnn(C4CCCCC4)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L05 compound treatment 647583.0 189000.0 0.39 634788.0 173000.0 0.37 0.5406 0.9998 1982873 ChemDiv1_027703 FC(F)Oc1ccc(c2cn3Cc4ccccc4-c3n2)c(OC(F)F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L06 compound treatment 674005.0 216000.0 0.44 684300.0 222000.0 0.48 0.6549 0.9992 1454865 ChemDiv1_027704 OC(CSc1ccccc1)CN2CC3CC(C2)c4cccc(=O)n4C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L07 compound treatment 735351.0 277000.0 0.57 700319.0 238000.0 0.52 0.769 0.9987 1982874 ChemDiv1_027705 O/C(=C\C(=O)c1ccccc1)/C(=O)/C=C/2\NC3(CCCCC3)Cc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L08 compound treatment 699852.0 241000.0 0.5 697071.0 235000.0 0.51 0.7122 0.9999 1982875 ChemDiv1_027706 CCOC(=O)C1(C)C/C(=N\NC(=O)c2ccccc2)/C(=O)N1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L09 compound treatment 715612.0 257000.0 0.53 696187.0 234000.0 0.51 0.7338 0.9997 1982876 ChemDiv1_027707 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccccc4Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L10 compound treatment 735172.0 277000.0 0.57 700543.0 239000.0 0.52 0.769 0.9987 1982877 ChemDiv1_027708 CCOC(=O)c1cccc(c1)N2C(=O)C3C(C2=O)C4(C(=O)C)c5ccccc5C3c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L11 compound treatment 715326.0 257000.0 0.53 696518.0 235000.0 0.51 0.7339 0.9998 1156079 ChemDiv1_027709 CC1(O)N(CCN)C(=O)OC21CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L12 compound treatment 703162.0 245000.0 0.51 661972.0 200000.0 0.43 0.6633 0.997 1982878 ChemDiv1_027710 S=C(NN=C1CSc2sc(=S)sc2SC1)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L13 compound treatment 722464.0 264000.0 0.54 701164.0 239000.0 0.52 0.7514 0.9997 1185930 ChemDiv1_027711 COc1cc(OC)cc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L14 compound treatment 729134.0 271000.0 0.56 720275.0 258000.0 0.56 0.7904 1.0 1982879 ChemDiv1_027712 Fc1ccccc1C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L15 compound treatment 738961.0 281000.0 0.58 739702.0 278000.0 0.6 0.8345 0.9998 1982880 ChemDiv1_027713 Brc1ccccc1c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L16 compound treatment 710231.0 252000.0 0.52 719020.0 257000.0 0.56 0.7609 0.9994 1328722 ChemDiv1_027714 OC1=C(C(N(C1=O)c2ccccn2)c3cccnc3)C(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L17 compound treatment 720270.0 262000.0 0.54 709843.0 248000.0 0.54 0.7615 1.0 1362834 ChemDiv1_027715 CCOC(=O)C1CCCn2c1nc3cc(sc3c2=O)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L18 compound treatment 708671.0 250000.0 0.52 693241.0 231000.0 0.5 0.7192 0.9999 1982881 ChemDiv1_027716 CC(C)n1c2ccccc2c3nnc(S)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L19 compound treatment 699386.0 241000.0 0.5 700289.0 238000.0 0.52 0.7164 0.9998 1982882 ChemDiv1_027717 CCOC(=O)C(NC(=O)c1ccccc1F)(Nc2nc3ccccc3nc2C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L20 compound treatment 720409.0 262000.0 0.54 713934.0 252000.0 0.55 0.768 1.0 1982883 ChemDiv1_027718 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(c2)C(F)(F)F)C#N)c3ccncc3)C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L21 compound treatment 710105.0 252000.0 0.52 731766.0 270000.0 0.58 0.7802 0.9983 1448276 ChemDiv1_027719 O=C1NC23NC(=O)NC3(N1)c4ccccc4-c5ccccc52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L22 compound treatment 1197621.0 739000.0 1.53 1202306.0 740000.0 1.6 2.212 0.9997 1982884 ChemDiv1_027720 CN(C)c1ccc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L23 mock treatment 690425.0 232000.0 0.48 709718.0 248000.0 0.54 0.7178 0.9984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 L24 mock treatment 229078.0 -229000.0 -0.47 224156.0 -238000.0 -0.51 -0.6988 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M01 compound treatment 634337.0 176000.0 0.36 563126.0 101000.0 0.22 0.4115 0.9707 1982885 ChemDiv1_027721 [O-][N+](=O)c1ccccc1C2CC(=Nc3ccccc3N2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M02 compound treatment 660354.0 202000.0 0.42 599783.0 138000.0 0.3 0.5056 0.9865 1982886 ChemDiv1_027722 COc1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M03 compound treatment 709447.0 251000.0 0.52 673926.0 212000.0 0.46 0.6908 0.9982 1982887 ChemDiv1_027723 Clc1cccc(c1)n2nnnc2C3(CCCCC3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M04 compound treatment 694263.0 236000.0 0.49 667848.0 206000.0 0.45 0.6593 0.999 1982888 ChemDiv1_027724 OC(=O)c1ccc2nc(c3ccc(cc3)c4ccccc4)c(nc2c1)c5ccc(cc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M05 compound treatment 687473.0 229000.0 0.47 676405.0 214000.0 0.46 0.6625 1.0 1982889 ChemDiv1_027725 CCCCN(CCCC)Cc1c(nnn1c2nonc2N)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M06 compound treatment 691146.0 233000.0 0.48 667872.0 206000.0 0.45 0.6548 0.9993 1203207 ChemDiv1_027726 CC1(C)CC(=C(C(C2C(=O)CC(C)(C)CC2=O)c3cccc(OCc4ccccc4)c3)C(=O)C1)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M07 compound treatment 720168.0 262000.0 0.54 669698.0 208000.0 0.45 0.6999 0.9958 1573362 ChemDiv1_027727 Fc1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M08 compound treatment 691265.0 233000.0 0.48 658156.0 196000.0 0.42 0.6401 0.9981 1982890 ChemDiv1_027728 COc1c(I)cc(I)cc1C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M09 compound treatment 736828.0 278000.0 0.57 677535.0 216000.0 0.47 0.7362 0.9947 1381303 ChemDiv1_027729 OC1=C(C(N(C1=O)c2nccs2)c3ccccc3)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M10 compound treatment 711193.0 253000.0 0.52 664890.0 203000.0 0.44 0.6795 0.9963 1669949 ChemDiv1_027730 Cn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M11 compound treatment 741140.0 283000.0 0.58 694974.0 233000.0 0.5 0.7692 0.9974 1982891 ChemDiv1_027731 FC(F)(F)C(F)(F)C1=NC(N=C(O1)c2cc(Cl)cc(Cl)c2)(C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M12 compound treatment 711488.0 253000.0 0.52 659267.0 197000.0 0.43 0.6713 0.995 1982892 ChemDiv1_027732 NC(=O)CSc1nc(cc(n1)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M13 compound treatment 747906.0 289000.0 0.6 676761.0 215000.0 0.46 0.7512 0.9923 1715080 ChemDiv1_027733 NS(=O)(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M14 compound treatment 938672.0 480000.0 0.99 941116.0 479000.0 1.04 1.4343 0.9997 1567311 ChemDiv1_027734 Brc1ccc(NC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M15 compound treatment 742120.0 284000.0 0.59 687453.0 225000.0 0.49 0.7591 0.9959 1581423 ChemDiv1_027735 Cc1ccc(s1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M16 compound treatment 708760.0 250000.0 0.52 640539.0 179000.0 0.39 0.6387 0.9898 1982893 ChemDiv1_027736 C/C(=N\O)/C=C/1\NC(C)(C)Cc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M17 compound treatment 718099.0 260000.0 0.54 680550.0 219000.0 0.47 0.7135 0.9981 1465898 ChemDiv1_027737 Oc1ccc(cc1O)c2nc(c([nH]2)c3ccccc3)c4ccc-5c(c4)C(=O)c6ccccc65 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M18 compound treatment 714611.0 256000.0 0.53 668895.0 207000.0 0.45 0.6906 0.9966 1982894 ChemDiv1_027738 COc1ccc(cc1)N2C(=N/C(=N\c3ccccc3)/C42CCCCC4)SC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M19 compound treatment 759340.0 301000.0 0.62 712801.0 251000.0 0.54 0.8231 0.9977 1982895 ChemDiv1_027739 COc1ccc(CCn2c(csc2=Nc3ccccc3)c4ccc(cc4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M20 compound treatment 704182.0 246000.0 0.51 667664.0 206000.0 0.45 0.6735 0.9979 1935974 ChemDiv1_027740 CC(=O)c1ccc2C(=O)c3ccccc3-c4onc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M21 compound treatment 721115.0 263000.0 0.54 710932.0 249000.0 0.54 0.7644 1.0 1982896 ChemDiv1_027741 CC(O)[C@]12CCCC[C@@H]2CC3C4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@@]31C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M22 compound treatment 711193.0 253000.0 0.52 683006.0 221000.0 0.48 0.7072 0.9991 1982897 ChemDiv1_027742 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4ccc(cc4)[N+](=O)[O-])cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M23 mock treatment 679506.0 221000.0 0.46 686485.0 225000.0 0.49 0.6663 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 M24 mock treatment 380477.0 -78000.0 -0.16 442585.0 -19400.0 -0.04 -0.1435 -0.8626 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N01 compound treatment 977551.0 519000.0 1.07 865138.0 403000.0 0.87 1.3747 0.9948 1677341 ChemDiv1_027743 Clc1ccc(NC(=O)c2cc3C4C=CCC4CN5CC6CC=CC6c(c2)c53)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N02 compound treatment 657488.0 199000.0 0.41 634571.0 173000.0 0.37 0.5547 0.9989 1131476 ChemDiv1_027744 CCc1ccc(cc1)C2(CC2C(=O)Nc3cccc(Br)c3)c4ccc(CC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N03 compound treatment 699943.0 241000.0 0.5 680958.0 219000.0 0.47 0.6876 0.9997 1982898 ChemDiv1_027745 CCCCOc1ccc(cc1)C2C=C(Nc3ccccc3)C(=O)N2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N04 compound treatment 652245.0 194000.0 0.4 632151.0 170000.0 0.37 0.5433 0.9991 1386572 ChemDiv1_027746 O=C1CC(C2COC1O2)n3nnn(Cc4ccccc4)c3=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N05 compound treatment 686339.0 228000.0 0.47 669358.0 207000.0 0.45 0.65 0.9997 1564049 ChemDiv1_027747 CC1(O)N(CC=C)C(=O)OC21CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N06 compound treatment 632923.0 174000.0 0.36 665638.0 204000.0 0.44 0.5664 0.995 1982899 ChemDiv1_027748 Fc1cccc(c1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N07 compound treatment 741806.0 283000.0 0.58 775846.0 314000.0 0.68 0.894 0.9972 1982900 ChemDiv1_027749 O[C@]1(NC(=C(C#N)[C@@H]([C@H]1[n+]2ccccc2)c3ccccc3F)S)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N08 compound treatment 698788.0 240000.0 0.5 661839.0 200000.0 0.43 0.6567 0.9977 1982901 ChemDiv1_027750 CC(C)COCC1CC2(CC(C)(OC2=O)C(=O)C)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N09 compound treatment 678340.0 220000.0 0.45 716744.0 255000.0 0.55 0.7109 0.9953 1982902 ChemDiv1_027751 CCC1(CC)Cc2ccccc2C(=N1)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N10 compound treatment 685802.0 227000.0 0.47 676458.0 214000.0 0.46 0.6601 1.0 1329918 ChemDiv1_027752 COc1cccc(c1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N11 compound treatment 686422.0 228000.0 0.47 675024.0 213000.0 0.46 0.6588 0.9999 1982903 ChemDiv1_027753 Cc1cc2CC(C)(C)N/C(=N\c3ccc(F)c(F)c3)/c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N12 compound treatment 625579.0 167000.0 0.34 647189.0 185000.0 0.4 0.5274 0.9972 1982904 ChemDiv1_027754 O=C(NN=C1CSc2sc(=S)sc2SC1)c3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N13 compound treatment 686231.0 228000.0 0.47 689782.0 228000.0 0.49 0.6811 0.9997 1193639 ChemDiv1_027755 COc1cc(OC)cc(c1)c2nc(c([nH]2)c3ccccc3)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N14 compound treatment 688405.0 230000.0 0.47 679616.0 218000.0 0.47 0.6687 1.0 1982905 ChemDiv1_027756 [O-][N+](=O)c1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N15 compound treatment 681290.0 223000.0 0.46 705165.0 243000.0 0.53 0.6975 0.9977 1982906 ChemDiv1_027757 COc1ccc(cc1OC)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N16 compound treatment 699831.0 241000.0 0.5 682837.0 221000.0 0.48 0.6904 0.9998 1982907 ChemDiv1_027758 CC1(C)CC2(CC(Oc3cc(O)ccc32)c4ccccc4)N=C(N1)SCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N17 compound treatment 686042.0 228000.0 0.47 708510.0 247000.0 0.53 0.7095 0.998 1194601 ChemDiv1_027759 COc1ccc(cc1)c2cc3nc4COCCn4c(=O)c3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N18 compound treatment 669024.0 211000.0 0.43 684324.0 222000.0 0.48 0.6477 0.9987 1982908 ChemDiv1_027760 CC1=C(CCC2(C)OC(=O)OC2=C)C(C)(C)CCC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N19 compound treatment 688046.0 230000.0 0.47 732316.0 270000.0 0.59 0.7489 0.9945 1982909 ChemDiv1_027761 OC1(C2CCCCCC2=NN1C(=O)COc3ccccc3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N20 compound treatment 681430.0 223000.0 0.46 698753.0 237000.0 0.51 0.6879 0.9986 1783174 ChemDiv1_027762 CC1(C)C2(CN3CN(C2)CC1(C3)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N21 compound treatment 705954.0 247000.0 0.51 714558.0 253000.0 0.55 0.7478 0.9994 1982910 ChemDiv1_027763 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)C4CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N22 compound treatment 665028.0 207000.0 0.43 701235.0 239000.0 0.52 0.6677 0.9953 1487431 ChemDiv1_027764 Cc1cc(=O)oc2c3c(Nc4ccccc4)coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N23 mock treatment 638661.0 180000.0 0.37 681405.0 219000.0 0.47 0.5989 0.9927 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 N24 mock treatment 378414.0 -80000.0 -0.17 473686.0 11700.0 0.03 -0.0989 -0.5917 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O01 compound treatment 723011.0 265000.0 0.55 631849.0 170000.0 0.37 0.6462 0.9815 1982911 ChemDiv1_027765 COc1ccc(cc1)C(=O)[C@H]2[C@H](c3ccc(SC)cc3)C(C#N)(C#N)[C@H]4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O02 compound treatment 638889.0 180000.0 0.37 592590.0 131000.0 0.28 0.4633 0.9907 1982912 ChemDiv1_027766 Cc1ccc(/C=C/C23NC(=O)CCN3c4ccccc4C2(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O03 compound treatment 687973.0 230000.0 0.47 601484.0 140000.0 0.3 0.5485 0.9763 1293333 ChemDiv1_027767 Ic1ccc(Nc2nc3nonc3n4cnnc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O04 compound treatment 664886.0 206000.0 0.43 605104.0 143000.0 0.31 0.5204 0.9877 1503314 ChemDiv1_027768 CCOC(=O)c1cnc2sc3ccccc3n2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O05 compound treatment 697606.0 239000.0 0.49 652496.0 191000.0 0.41 0.6407 0.996 1690735 ChemDiv1_027769 CCOC(=O)c1nnn(c1CNC(C)C)c2nonc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O06 compound treatment 647024.0 189000.0 0.39 619734.0 158000.0 0.34 0.5167 0.9979 1982913 ChemDiv1_027770 COc1ccc(cc1Br)c2csc(=Nc3ccccc3)n2CCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O07 compound treatment 695158.0 237000.0 0.49 649580.0 188000.0 0.41 0.6326 0.9958 1982914 ChemDiv1_027771 COc1ccc(cc1)N2C(=O)C3ON(C4SC(=S)N(C)C4(C)C)C(C3C2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O08 compound treatment 661227.0 203000.0 0.42 656433.0 194000.0 0.42 0.5936 1.0 1982915 ChemDiv1_027772 Cc1ccc(C)c(/N=C/2\c3ccccc3-c4nc5ccccc5cc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O09 compound treatment 696347.0 238000.0 0.49 668654.0 207000.0 0.45 0.6636 0.9989 1982916 ChemDiv1_027773 CC(=O)NC1(CCCCC1)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O10 compound treatment 628115.0 170000.0 0.35 622986.0 161000.0 0.35 0.4941 1.0 1563682 ChemDiv1_027774 Clc1ccc(cc1)c2csc(=Nc3ccccn3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O11 compound treatment 913268.0 455000.0 0.94 647623.0 186000.0 0.4 0.948 0.9283 1982917 ChemDiv1_027775 FC(F)(F)C1(N=C(OC(=N1)c2ccco2)N3CCCCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O12 compound treatment 666502.0 208000.0 0.43 653079.0 191000.0 0.41 0.5962 0.9998 1982918 ChemDiv1_027776 CC(=O)C1=NN(C(N1c2ccc(C)cc2)c3cccs3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O13 compound treatment 692441.0 234000.0 0.48 679381.0 217000.0 0.47 0.6743 0.9999 1543347 ChemDiv1_027777 CC1(C)OC(=O)N(CCN2C(=O)OC(C)(C)C2(C)O)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O14 compound treatment 664565.0 206000.0 0.43 619515.0 158000.0 0.34 0.542 0.994 1982919 ChemDiv1_027778 O=C(CC#N)NN=C1CSc2sc(=S)sc2SC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O15 compound treatment 715793.0 257000.0 0.53 694808.0 233000.0 0.5 0.732 0.9997 1244588 ChemDiv1_027779 CCC1(C)OC(=O)N(CCC#N)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O16 compound treatment 646521.0 188000.0 0.39 671936.0 210000.0 0.45 0.5959 0.9969 1982920 ChemDiv1_027780 CC1(C)Cc2ccccc2/C(=N\c3ccc(F)c(F)c3)/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O17 compound treatment 710387.0 252000.0 0.52 665097.0 203000.0 0.44 0.6786 0.9965 1480239 ChemDiv1_027781 COc1ccc(cc1)c2nc([nH]c2c3ccc(OC)cc3)c4cc(OC)ccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O18 compound treatment 650912.0 192000.0 0.4 647454.0 185000.0 0.4 0.5648 1.0 1453218 ChemDiv1_027782 Brc1cccc(c1)n2c3ccccc3cc4c(=O)[nH]c(=O)nc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O19 compound treatment 704466.0 246000.0 0.51 673789.0 212000.0 0.46 0.6833 0.9987 1301252 ChemDiv1_027783 NS(=O)(=O)c1ccc(CCn2c(csc2=Nc3ccc(F)cc3)c4ccc5ccccc5c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O20 compound treatment 638678.0 180000.0 0.37 638082.0 176000.0 0.38 0.5326 0.9999 1982921 ChemDiv1_027784 CC1CCC(CC1)(N(C)C)c2nnnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O21 compound treatment 701862.0 243000.0 0.5 663902.0 202000.0 0.44 0.6643 0.9976 1287877 ChemDiv1_027785 CCCS(=O)(=O)c1c(C(=O)c2ccc(C)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O22 compound treatment 676060.0 218000.0 0.45 666400.0 204000.0 0.44 0.6305 1.0 1982922 ChemDiv1_027786 CN(C)c1ccc(cc1)C2N(N=C(N2c3ccc(C)cc3)C(=O)C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O23 mock treatment 671974.0 214000.0 0.44 650693.0 189000.0 0.41 0.6005 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 O24 mock treatment 326527.0 -132000.0 -0.27 411725.0 -50200.0 -0.11 -0.2695 -0.9189 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P01 compound treatment 609075.0 151000.0 0.31 567263.0 105000.0 0.23 0.381 0.9883 1412022 ChemDiv1_027787 COc1ccc(cc1)C(=O)CCNc2ccc3OCCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P02 compound treatment 650552.0 192000.0 0.4 582426.0 120000.0 0.26 0.4647 0.9793 1425783 ChemDiv1_027788 CCCS(=O)(=O)c1c(C(=O)c2ccc(Cl)cc2)n3ccncc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P03 compound treatment 600693.0 142000.0 0.29 565614.0 104000.0 0.22 0.3662 0.9912 1982923 ChemDiv1_027789 C1CCC2(CC1)Cc3ccccc3/C(=N/c4ccccc4)/N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P04 compound treatment 605533.0 147000.0 0.3 559369.0 97400.0 0.21 0.3637 0.9841 1941107 ChemDiv1_027790 CN1C(=O)N(C)C2(N(N)C(=N)NC12c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P05 compound treatment 602821.0 144000.0 0.3 586703.0 125000.0 0.27 0.4016 0.9988 1287809 ChemDiv1_027791 CCN1C(=O)OC2(CCCCC2)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P06 compound treatment 614865.0 156000.0 0.32 588872.0 127000.0 0.27 0.4225 0.9968 1165394 ChemDiv1_027792 CCOC(=O)Cn1c2ccccc2n3nc(C)c(=O)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P07 compound treatment 631168.0 173000.0 0.36 607186.0 145000.0 0.31 0.4743 0.998 1982924 ChemDiv1_027793 COc1ccc(CCn2c(csc2=Nc3cccc(c3)C(F)(F)F)c4ccc(cc4)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P08 compound treatment 631970.0 174000.0 0.36 616815.0 155000.0 0.34 0.4903 0.9994 1982925 ChemDiv1_027794 CCCOCC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4Cl)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P09 compound treatment 636802.0 178000.0 0.37 587710.0 126000.0 0.27 0.4528 0.9889 1697771 ChemDiv1_027795 CC1(C)CC2(CC(Oc3cc(O)ccc32)c4ccccc4)NC(=O)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P10 compound treatment 616771.0 158000.0 0.33 612112.0 150000.0 0.32 0.4609 1.0 1306676 ChemDiv1_027796 CCN1C(=c2sc(=C3C(=O)c4ccccc4C3=O)n(C)c2=O)C=Cc5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P11 compound treatment 640093.0 182000.0 0.37 624854.0 163000.0 0.35 0.5144 0.9995 1670350 ChemDiv1_027797 O=C1CC(=O)N(C(=S)N1c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P12 compound treatment 613061.0 155000.0 0.32 626590.0 165000.0 0.36 0.4776 0.9985 1982926 ChemDiv1_027798 O=c1sc2SCC(=NNC(=S)Nc3ccccc3)CSc2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P13 compound treatment 626412.0 168000.0 0.35 620296.0 158000.0 0.34 0.4875 1.0 1982927 ChemDiv1_027799 COc1cccc(c2nnc3ccc4ccccc4n23)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P14 compound treatment 615329.0 157000.0 0.32 613520.0 152000.0 0.33 0.4609 1.0 1132706 ChemDiv1_027800 COc1ccccc1C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P15 compound treatment 647609.0 189000.0 0.39 606767.0 145000.0 0.31 0.4977 0.9941 1945546 ChemDiv1_027801 Brc1ccc2[nH]cc(c3nnc4ccc5ccccc5n34)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P16 compound treatment 672643.0 214000.0 0.44 637118.0 175000.0 0.38 0.5807 0.9971 1982928 ChemDiv1_027802 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccc(O)cc4)/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P17 compound treatment 658776.0 200000.0 0.41 633317.0 171000.0 0.37 0.5546 0.9985 1506410 ChemDiv1_027803 CCOC(=O)C1=NN(C2C1C(=O)N(C2=O)c3ccc(Cl)cc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P18 compound treatment 647132.0 189000.0 0.39 634771.0 173000.0 0.37 0.5399 0.9998 1526037 ChemDiv1_027804 S=c1n(CN2CCC3(CC2)OCCO3)nc(c4ccccc4)n1c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P19 compound treatment 656339.0 198000.0 0.41 604297.0 142000.0 0.31 0.5067 0.9903 1595446 ChemDiv1_027805 NNc1nc(N)c2c(n1)-c3ccccc3CC42CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P20 compound treatment 641284.0 183000.0 0.38 596557.0 135000.0 0.29 0.4728 0.9918 1783173 ChemDiv1_027806 [O-][N+](=O)C1(CN2CN3C1)CC(C2)(C3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P21 compound treatment 632454.0 174000.0 0.36 621078.0 159000.0 0.34 0.4975 0.9998 1982929 ChemDiv1_027807 NC(=O)NN=C1CSc2sc(=S)sc2SC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P22 compound treatment 636186.0 178000.0 0.37 614227.0 152000.0 0.33 0.4924 0.9986 1982930 ChemDiv1_027808 Cc1cc2CSC(SCc2cc1C)c3cc(Br)ccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P23 mock treatment 620132.0 162000.0 0.33 615155.0 153000.0 0.33 0.4704 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.665 P24 mock treatment 223821.0 -235000.0 -0.48 204752.0 -257000.0 -0.56 -0.7362 -0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A01 compound treatment 609148.0 151000.0 0.31 573626.0 105000.0 0.23 0.3809 0.9878 1982931 ChemDiv1_027809 Cc1cc2CSC(SCc2cc1C)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A02 compound treatment 570405.0 112000.0 0.23 557553.0 88700.0 0.19 0.2997 0.9956 1395871 ChemDiv1_027810 O=C1CC(C2COC1O2)n3c(=S)n(Cc4ccccc4)c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A03 compound treatment 613454.0 155000.0 0.32 582777.0 114000.0 0.25 0.4012 0.9916 1782957 ChemDiv1_027811 COc1ccc(Br)cc1S(=O)(=O)n2c(C)ncc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A04 compound treatment 619189.0 161000.0 0.33 588538.0 120000.0 0.26 0.4183 0.9924 1434476 ChemDiv1_027812 Fc1ccccc1Nc2nc3nonc3n4nnnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A05 compound treatment 642971.0 185000.0 0.38 601120.0 132000.0 0.29 0.4723 0.99 1982932 ChemDiv1_027813 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2ccc(C)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A06 compound treatment 648568.0 190000.0 0.39 642269.0 173000.0 0.38 0.5435 0.9997 1496976 ChemDiv1_027814 Clc1ccc(cc1)C2C3C(N4CCCN24)C(=O)N(C3=O)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A07 compound treatment 1277712.0 820000.0 1.69 1298757.0 830000.0 1.8 2.4665 0.9996 1338661 ChemDiv1_027815 COc1cc(C=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)cc(Br)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A08 compound treatment 661064.0 203000.0 0.42 631448.0 163000.0 0.35 0.5451 0.9962 1347843 ChemDiv1_027816 CCOc1ccccc1NC(=O)c2c(NC(=O)c3cccc(F)c3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A09 compound treatment 637513.0 179000.0 0.37 625194.0 156000.0 0.34 0.5012 0.999 1982933 ChemDiv1_027817 CCOc1ccc(cc1)N2C(=O)C(=O)C3=C(Nc4ccccc4SC23C(=O)OC)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A10 compound treatment 642035.0 184000.0 0.38 620355.0 152000.0 0.33 0.5004 0.9973 1349886 ChemDiv1_027818 CC1(C)OC(=O)N(C2CC(C)(C)NC(C)(C)C2)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A11 compound treatment 639465.0 181000.0 0.37 613704.0 145000.0 0.31 0.4865 0.9961 1982934 ChemDiv1_027819 CC(=O)C1=C(S/C(=C\2/C(=S)C(C)(C)Nc3ccc(C)cc23)/S1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A12 compound treatment 650202.0 192000.0 0.4 624199.0 155000.0 0.34 0.5182 0.9966 1982935 ChemDiv1_027820 Cc1cc(C)c(C2C(=O)[C@@H]3[C@H](N4CCCN4[C@@H]3C2=O)c5ccccc5)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A13 compound treatment 649401.0 191000.0 0.39 621002.0 152000.0 0.33 0.5121 0.9959 1532628 ChemDiv1_027821 CN1c2ccc(Cl)cc2-c3c(sn(c4cccc(C)c4)c3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A14 compound treatment 666820.0 209000.0 0.43 621798.0 153000.0 0.33 0.5388 0.9915 1257837 ChemDiv1_027822 CC(=O)OC1CCC2(C=O)C3CCC4(C)CC(CC4(O)C3CCC2(O)C1)C5=CC(=O)OC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A15 compound treatment 726571.0 268000.0 0.55 679156.0 210000.0 0.46 0.7138 0.9952 1982936 ChemDiv1_027823 CCN1/C(=C\2/SC(=S)NC2=O)/Sc3ccc(OC)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A16 compound treatment 673447.0 215000.0 0.44 626180.0 157000.0 0.34 0.5552 0.9913 1949594 ChemDiv1_027824 Oc1ccc(Br)cc1c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A17 compound treatment 1101223.0 643000.0 1.33 950618.0 482000.0 1.04 1.6761 0.9929 1417630 ChemDiv1_027825 CCN1C(=c2sc(=C3SC(=S)N(C)C3=O)n(CC=C)c2=O)Sc4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A18 compound treatment 844485.0 386000.0 0.8 849105.0 380000.0 0.82 1.146 0.9999 1729923 ChemDiv1_027826 NC1=C(C#N)C2=CCN(Cc3ccccc3)CC2C(c4cccc5ccccc45)C1(C#N)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A19 compound treatment 647614.0 190000.0 0.39 656214.0 187000.0 0.41 0.5634 0.9998 1365468 ChemDiv1_027827 CC1CC(=O)Nc2ccccc2N1C(=O)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A20 compound treatment 629028.0 171000.0 0.35 611360.0 143000.0 0.31 0.4676 0.9978 1982937 ChemDiv1_027828 CNC1(CCCCC1)c2nnnn2c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A21 compound treatment 597488.0 139000.0 0.29 585592.0 117000.0 0.25 0.3822 0.9979 1982938 ChemDiv1_027829 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccc(cc2)S(=O)(=O)N)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A22 compound treatment 618649.0 161000.0 0.33 606194.0 137000.0 0.3 0.4446 0.9985 1671843 ChemDiv1_027830 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)c(Cl)c2)C#N)c3ccco3)C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A23 mock treatment 574510.0 116000.0 0.24 576033.0 107000.0 0.23 0.334 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 A24 mock treatment 190825.0 -267000.0 -0.55 208386.0 -260000.0 -0.56 -0.7887 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B01 compound treatment 628087.0 170000.0 0.35 578734.0 110000.0 0.24 0.4163 0.982 1523176 ChemDiv1_027831 CN1C2C(N(CN3CCCCC3)C1=O)N(CN4CCCCC4)C(=O)N2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B02 compound treatment 653353.0 195000.0 0.4 604505.0 136000.0 0.29 0.4926 0.9879 1982939 ChemDiv1_027832 CCN(CC)P(=NN=Nc1ccc2nnnn2n1)(N(CC)CC)N(CC)CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B03 compound treatment 883478.0 425000.0 0.88 861376.0 393000.0 0.85 1.2217 0.9999 1982940 ChemDiv1_027833 CC(=O)C1=NN(C(N1c2ccc(C)cc2)c3c[nH]c4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B04 compound treatment 677969.0 220000.0 0.45 656933.0 188000.0 0.41 0.6088 0.9985 1711433 ChemDiv1_027834 Cn1c(=O)n(C)c2nc3n(Cc4ccccc4)c(cn3c2c1=O)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B05 compound treatment 717768.0 260000.0 0.54 693002.0 224000.0 0.49 0.7221 0.9988 1982941 ChemDiv1_027835 CCOc1cccc(C2N(N=C(N2c3ccc(Cl)cc3)C(=O)C)c4ccccc4)c1OCc5ccccc5Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B06 compound treatment 776683.0 319000.0 0.66 728332.0 259000.0 0.56 0.8622 0.9969 1678689 ChemDiv1_027836 C1CCc2nn3cc(nc3nc2C1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B07 compound treatment 709792.0 252000.0 0.52 691701.0 223000.0 0.48 0.7085 0.9993 1472804 ChemDiv1_027837 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccc(Br)cc4)c5ccc(Oc6ccccc6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B08 compound treatment 700137.0 242000.0 0.5 679569.0 211000.0 0.46 0.6758 0.999 1982942 ChemDiv1_027838 Ic1cccc(c1)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B09 compound treatment 731202.0 273000.0 0.56 710486.0 242000.0 0.52 0.7685 0.9993 1982943 ChemDiv1_027839 COc1cc2CC(C)(C)N=C(CCCCCl)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B10 compound treatment 727892.0 270000.0 0.56 688724.0 220000.0 0.48 0.7303 0.9969 1489229 ChemDiv1_027840 OCCCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B11 compound treatment 723690.0 266000.0 0.55 681843.0 213000.0 0.46 0.7137 0.9963 1718663 ChemDiv1_027841 Cc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B12 compound treatment 720206.0 262000.0 0.54 694163.0 225000.0 0.49 0.7274 0.9987 1176172 ChemDiv1_027842 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(Cl)c2)C#N)c3ccco3)C(=O)Nc4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B13 compound treatment 743452.0 285000.0 0.59 715597.0 247000.0 0.53 0.7942 0.9988 1982944 ChemDiv1_027843 Brc1ccc2N(CC(=O)N/N=C/c3ccccc3)C(=O)CN=C(c4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B14 compound treatment 717011.0 259000.0 0.53 684815.0 216000.0 0.47 0.7085 0.9978 1284846 ChemDiv1_027844 COc1c(Cl)cc(Cl)cc1C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B15 compound treatment 788796.0 331000.0 0.68 714178.0 245000.0 0.53 0.8582 0.9923 1478857 ChemDiv1_027845 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B16 compound treatment 730095.0 272000.0 0.56 699005.0 230000.0 0.5 0.7493 0.9982 1361704 ChemDiv1_027846 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B17 compound treatment 741049.0 283000.0 0.58 718233.0 249000.0 0.54 0.7947 0.9992 1534039 ChemDiv1_027847 O=C1N(C(C2=C1NCCN=C2c3ccccc3)c4ccc5OCOc5c4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B18 compound treatment 695935.0 238000.0 0.49 672671.0 204000.0 0.44 0.6591 0.9986 1982945 ChemDiv1_027848 CCOC(=O)C(NC(=O)c1ccccc1F)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B19 compound treatment 729444.0 271000.0 0.56 745721.0 277000.0 0.6 0.8198 0.9994 1982946 ChemDiv1_027849 Cc1cc(=O)oc2c3c(Nc4cccc(c4)[N+](=O)[O-])coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B20 compound treatment 704521.0 246000.0 0.51 675283.0 206000.0 0.45 0.6757 0.9979 1400336 ChemDiv1_027850 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B21 compound treatment 684295.0 226000.0 0.47 699644.0 231000.0 0.5 0.6834 0.9994 1982947 ChemDiv1_027851 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)CNCCCO 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B22 compound treatment 671773.0 214000.0 0.44 667945.0 199000.0 0.43 0.6166 0.9999 1516542 ChemDiv1_027852 COc1ccc(C2N(C(=O)c3[nH]nc(c23)c4ccc(C)cc4)c5ccc(F)cc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B23 mock treatment 661762.0 204000.0 0.42 660670.0 192000.0 0.42 0.5909 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 B24 mock treatment 314150.0 -144000.0 -0.3 188301.0 -281000.0 -0.61 -0.6395 -0.9459 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C01 compound treatment 623405.0 165000.0 0.34 581201.0 112000.0 0.24 0.4133 0.9862 1389618 ChemDiv1_027853 COc1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C02 compound treatment 642282.0 184000.0 0.38 624841.0 156000.0 0.34 0.5076 0.9982 1982948 ChemDiv1_027854 CN1C(=O)N(C)C2(NC(=S)NNC12c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C03 compound treatment 685637.0 228000.0 0.47 701700.0 233000.0 0.5 0.6885 0.9994 1982949 ChemDiv1_027855 CCC1(C(c2ccc(Br)cc2)C1(C(=O)OC)C(=O)OC)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C04 compound treatment 679860.0 222000.0 0.46 676605.0 208000.0 0.45 0.6417 1.0 1631056 ChemDiv1_027856 Cn1cnc2n(C)c(=O)n(Cc3cccc(F)c3)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C05 compound treatment 684086.0 226000.0 0.47 674302.0 205000.0 0.44 0.6443 0.9997 1731920 ChemDiv1_027857 COc1ccc(c2ccccc12)S(=O)(=O)n3nnc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C06 compound treatment 657614.0 200000.0 0.41 664690.0 196000.0 0.42 0.591 0.9999 1982950 ChemDiv1_027858 O=C/1OC(=C\C1=C\2/c3ccccc3-c4ncccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C07 compound treatment 703720.0 246000.0 0.51 710685.0 242000.0 0.52 0.7287 0.9999 1532578 ChemDiv1_027859 CCN1CCN(Cc2c(nnn2c3nonc3N)C(=O)OC(C)C)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C08 compound treatment 692600.0 235000.0 0.48 713111.0 244000.0 0.53 0.7162 0.999 1388540 ChemDiv1_027860 COC(=O)C1C2c3ccccc3O[C@]1(C)N=c4sc(=Cc5cccc(OC)c5)c(=O)n24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C09 compound treatment 968622.0 511000.0 1.05 1026025.0 557000.0 1.21 1.598 0.9977 1982951 ChemDiv1_027861 Nc1nc2cccc3C(=O)c4ccccc4-c(c1C#N)c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C10 compound treatment 678340.0 220000.0 0.45 675874.0 207000.0 0.45 0.6383 1.0 1982952 ChemDiv1_027862 ClCCNc1ccccc1CP(=O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C11 compound treatment 713174.0 255000.0 0.53 682659.0 214000.0 0.46 0.6996 0.9979 1982953 ChemDiv1_027863 CCOc1ccc2N(C(=O)C(C)CC)C(C)(C)C(=S)C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C12 compound treatment 672207.0 214000.0 0.44 676415.0 208000.0 0.45 0.6302 1.0 1982954 ChemDiv1_027864 Brc1ccc(cc1)C2NC(=S)NC(=C2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C13 compound treatment 703392.0 245000.0 0.51 698237.0 229000.0 0.5 0.7091 1.0 1982955 ChemDiv1_027865 CCCCC(=O)N1c2ccc(OCC)cc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C14 compound treatment 682597.0 225000.0 0.46 698747.0 230000.0 0.5 0.6796 0.9994 1982956 ChemDiv1_027866 FC(F)(F)C1(N=C(OC(=N1)c2ccncc2)N3CCCCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C15 compound treatment 741886.0 284000.0 0.59 744921.0 276000.0 0.6 0.8368 1.0 1982957 ChemDiv1_027867 CCN/1C(=C(C)S\C1=C\2/SC(=S)N(N)C2=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C16 compound treatment 713549.0 255000.0 0.53 717939.0 249000.0 0.54 0.7541 0.9999 1982958 ChemDiv1_027868 CCOC(=O)C(NC(=O)c1cccc(c1)C(F)(F)F)(Nc2sc3CCCCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C17 compound treatment 752548.0 294000.0 0.61 736991.0 268000.0 0.58 0.8402 0.9997 1725861 ChemDiv1_027869 COc1ccc(C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C18 compound treatment 715300.0 257000.0 0.53 698479.0 230000.0 0.5 0.7269 0.9995 1982959 ChemDiv1_027870 Cn1c2Oc3ccccc3NC(c4ccc(cc4)[N+](=O)[O-])c2c(=O)n(C)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C19 compound treatment 717336.0 259000.0 0.54 779916.0 311000.0 0.67 0.8545 0.9935 1667444 ChemDiv1_027871 CC(=O)N1CCC(=O)N(C(=O)c2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C20 compound treatment 668927.0 211000.0 0.44 663765.0 195000.0 0.42 0.6061 0.9999 1141527 ChemDiv1_027872 Cc1cc(=O)oc2c3c(Nc4ccc(O)cc4)coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C21 compound treatment 679592.0 222000.0 0.46 693680.0 225000.0 0.49 0.6674 0.9995 1982960 ChemDiv1_027873 CC1(C)CC2(CC(Oc3cc(O)c(Cl)cc32)c4ccccc4Cl)N=C(N1)SCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C22 compound treatment 641305.0 183000.0 0.38 669628.0 201000.0 0.43 0.5747 0.9976 1256872 ChemDiv1_027874 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C23 mock treatment 652439.0 194000.0 0.4 673925.0 205000.0 0.44 0.5976 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 C24 mock treatment 218491.0 -240000.0 -0.49 211957.0 -257000.0 -0.56 -0.7429 -0.9983 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D01 compound treatment 656866.0 199000.0 0.41 606309.0 137000.0 0.3 0.5005 0.9875 1982961 ChemDiv1_027875 CCC1(CC)Cc2cc(OC)c(OC)cc2C(=N1)CCl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D02 compound treatment 663236.0 205000.0 0.42 632653.0 164000.0 0.35 0.5502 0.9961 1982962 ChemDiv1_027876 Cc1c2CCN3C(=O)OC(C)(C)C3(C)c4cccc(n1C)c24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D03 compound treatment 1277626.0 820000.0 1.69 1321214.0 852000.0 1.84 2.5008 0.9991 1982963 ChemDiv1_027877 CC(=O)C1=NN(C(N1c2ccc(F)cc2)c3c[nH]c4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D04 compound treatment 687014.0 229000.0 0.47 669011.0 200000.0 0.43 0.6405 0.9991 1444540 ChemDiv1_027878 Cc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D05 compound treatment 849329.0 391000.0 0.81 928691.0 460000.0 1.0 1.2749 0.9946 1982964 ChemDiv1_027879 CC(=O)C1=NN(C(N1c2ccc(N3CCCCC3)c(Cl)c2)c4c[nH]c5ccccc45)c6ccc(C)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D06 compound treatment 678240.0 220000.0 0.45 644556.0 176000.0 0.38 0.5903 0.9961 1982965 ChemDiv1_027880 [O-][N+](=O)c1cc(C2Oc3[nH]c(=O)[nH]c(=O)c23)c(cc1N4CCOCC4)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D07 compound treatment 709641.0 252000.0 0.52 704228.0 235000.0 0.51 0.7274 1.0 1663027 ChemDiv1_027881 CC(C)N1C(C2C(C)NC(=O)N(C(C)C)C2NC1=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D08 compound treatment 684916.0 227000.0 0.47 706001.0 237000.0 0.51 0.6941 0.9989 1982966 ChemDiv1_027882 Clc1ccc(cc1Cl)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D09 compound treatment 721443.0 263000.0 0.54 711272.0 242000.0 0.52 0.7554 0.9998 1982967 ChemDiv1_027883 Clc1ccc(NC(=O)Cc2c(Sc3ccccc3)c4ccccc4n2Cc5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D10 compound treatment 723386.0 265000.0 0.55 697168.0 228000.0 0.49 0.7367 0.9987 1638663 ChemDiv1_027884 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccncc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D11 compound treatment 707725.0 250000.0 0.52 723835.0 255000.0 0.55 0.7546 0.9994 1296316 ChemDiv1_027885 COc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D12 compound treatment 687679.0 230000.0 0.47 676362.0 208000.0 0.45 0.6527 0.9996 1371779 ChemDiv1_027886 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(Cl)c2C)C#N)c3ccco3)C(=O)Nc4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D13 compound treatment 703561.0 245000.0 0.51 699279.0 230000.0 0.5 0.711 1.0 1982968 ChemDiv1_027887 COc1ccc-2c(c1)C(=NNC(=N)N)c3cc(OC)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D14 compound treatment 736469.0 278000.0 0.57 707533.0 239000.0 0.52 0.7717 0.9986 1385060 ChemDiv1_027888 CCOc1cc(ccc1OCc2ccccc2)C3C4=C(CC(C)(C)CC4=O)N(C)C5=C3C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D15 compound treatment 765866.0 308000.0 0.64 738333.0 269000.0 0.58 0.8617 0.9991 1495106 ChemDiv1_027889 Oc1ccc2NS(=O)(=O)c3ccc(Cl)cc3-c2c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D16 compound treatment 733981.0 276000.0 0.57 716643.0 248000.0 0.54 0.782 0.9995 1616757 ChemDiv1_027890 COc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D17 compound treatment 767981.0 310000.0 0.64 779740.0 311000.0 0.67 0.9282 0.9997 1644439 ChemDiv1_027891 COc1ccc(cc1)C2NC(=S)NC(=C2)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D18 compound treatment 716739.0 259000.0 0.53 692584.0 224000.0 0.48 0.72 0.9988 1982969 ChemDiv1_027892 CCOC(=O)C(NC(=O)c1ccc(F)cc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D19 compound treatment 737922.0 280000.0 0.58 701541.0 233000.0 0.5 0.7646 0.9977 1982970 ChemDiv1_027893 CCOC(=O)C1(C)C=C(Nc2cccc(Cl)c2)C(=O)N1c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D20 compound treatment 716750.0 259000.0 0.53 680814.0 212000.0 0.46 0.702 0.9971 1362969 ChemDiv1_027894 COc1cccc(c1)C(=O)Cn2c(Br)nc3n(C)c(=O)n(C)c(=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D21 compound treatment 735330.0 277000.0 0.57 723895.0 255000.0 0.55 0.795 0.9998 1737536 ChemDiv1_027895 Cc1ccc(cc1)C(=O)N2C(CC(=Nc3ccccc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D22 compound treatment 699649.0 242000.0 0.5 669856.0 201000.0 0.44 0.6602 0.9977 1982971 ChemDiv1_027896 Cc1ccc(cc1)C(O)(C(=O)NN(C(=O)c2cccnc2Cl)c3ccccc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D23 mock treatment 682663.0 225000.0 0.46 682509.0 214000.0 0.46 0.6548 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 D24 mock treatment 247005.0 -211000.0 -0.44 206637.0 -262000.0 -0.57 -0.7094 -0.9915 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E01 compound treatment 626721.0 169000.0 0.35 573432.0 105000.0 0.23 0.4062 0.9783 1982972 ChemDiv1_027897 Fc1ccc(cc1)C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5cccc(c5)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E02 compound treatment 651395.0 193000.0 0.4 610489.0 142000.0 0.31 0.4989 0.9915 1263755 ChemDiv1_027898 OC(=O)c1ccc(cc1O)N2C(C(=C(O)C2=O)C(=O)c3ccccc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E03 compound treatment 719657.0 262000.0 0.54 698464.0 230000.0 0.5 0.7332 0.9991 1326908 ChemDiv1_027899 N(c1ccccc1)c2nc3nonc3n4cnnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E04 compound treatment 683471.0 225000.0 0.47 667082.0 198000.0 0.43 0.6324 0.9992 1624225 ChemDiv1_027900 OC12NC(=S)N(CC=C)C2(O)C(=O)c3ccccc31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E05 compound treatment 705728.0 248000.0 0.51 662744.0 194000.0 0.42 0.6582 0.9952 1782956 ChemDiv1_027901 COc1ccc(Cl)cc1S(=O)(=O)n2c(C)ncc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E06 compound treatment 709160.0 251000.0 0.52 665445.0 197000.0 0.43 0.6674 0.9952 1982973 ChemDiv1_027902 Cc1cc(=O)oc2c3C(=O)/C(=C/c4cc(Br)ccc4O)/Oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E07 compound treatment 707596.0 250000.0 0.52 691091.0 222000.0 0.48 0.7043 0.9994 1377848 ChemDiv1_027903 CC(=O)Nc1nc2CCC(Cc2c3c4ccccc4oc(=O)c13)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E08 compound treatment 694484.0 236000.0 0.49 687370.0 219000.0 0.47 0.6795 0.9999 1539745 ChemDiv1_027904 COC(=O)c1cc(ccc1Cl)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)c(c3)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E09 compound treatment 708702.0 251000.0 0.52 716378.0 248000.0 0.54 0.7447 0.9998 1671054 ChemDiv1_027905 CCOC(=O)c1nc2cc3C(=C(C)C(C)n3c(CC(C)C)c2c1C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E10 compound treatment 673922.0 216000.0 0.45 673192.0 204000.0 0.44 0.6278 1.0 1982974 ChemDiv1_027906 COc1ccc(cc1)C2=NN(C(=O)C)C3(SC(=NN3c4ccccc4)C(=O)C)N2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E11 compound treatment 703428.0 245000.0 0.51 708556.0 240000.0 0.52 0.725 0.9999 1927704 ChemDiv1_027907 O=C(N1CCSC1c2ccc3CCc4cccc2c43)C5=CC6C=CC=CC6OC5=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E12 compound treatment 716026.0 258000.0 0.53 705454.0 237000.0 0.51 0.7386 0.9998 1537140 ChemDiv1_027908 Clc1cc(Cl)c2OC3(CCCCCC3=Cc2c1)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E13 compound treatment 715533.0 257000.0 0.53 691869.0 223000.0 0.48 0.7171 0.9988 1982975 ChemDiv1_027909 CCCN1c2ccccc2C3=C(SC(=C(C(=O)OC)C43SC(=C(S4)C(=O)OC)C(=O)OC)C(=O)OC)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E14 compound treatment 702327.0 244000.0 0.5 675321.0 206000.0 0.45 0.6725 0.9982 1982976 ChemDiv1_027910 FC(F)(F)C1(N=C(OC(=N1)c2ccncc2)N3CCOCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E15 compound treatment 741704.0 284000.0 0.59 733669.0 265000.0 0.57 0.8193 0.9999 1714682 ChemDiv1_027911 CCOC(=O)c1ccc(cc1)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)cc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E16 compound treatment 711298.0 253000.0 0.52 707512.0 239000.0 0.52 0.7349 1.0 1413655 ChemDiv1_027912 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccccc4)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E17 compound treatment 743870.0 286000.0 0.59 711644.0 243000.0 0.53 0.7887 0.9983 1982977 ChemDiv1_027913 CCc1c(oc2ccc3c(C)cc(=O)oc3c12)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E18 compound treatment 707688.0 250000.0 0.52 699776.0 231000.0 0.5 0.7178 0.9999 1352687 ChemDiv1_027914 C1C(Nc2ncnn2C1c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E19 compound treatment 725915.0 268000.0 0.55 695143.0 226000.0 0.49 0.7373 0.9982 1524730 ChemDiv1_027915 CC(=O)N1CCC(=O)N(Cc2ccccc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E20 compound treatment 714669.0 257000.0 0.53 678536.0 210000.0 0.45 0.6955 0.997 1482190 ChemDiv1_027916 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc3CCc4ccccc4N(C(=O)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E21 compound treatment 700233.0 242000.0 0.5 694253.0 225000.0 0.49 0.6984 0.9999 1712737 ChemDiv1_027917 COC(=O)C1(OC)N(C(=O)C(=C1C(=O)c2ccc(Cl)cc2)OC)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E22 compound treatment 681440.0 223000.0 0.46 669080.0 200000.0 0.43 0.6325 0.9995 1583917 ChemDiv1_027918 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4cc(C)ccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E23 mock treatment 674745.0 217000.0 0.45 687811.0 219000.0 0.47 0.6514 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 E24 mock treatment 248775.0 -209000.0 -0.43 254461.0 -214000.0 -0.46 -0.6336 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F01 compound treatment 615143.0 157000.0 0.32 606675.0 138000.0 0.3 0.4402 0.9991 1982978 ChemDiv1_027919 [O-][N+](=O)c1ccc2N3C4C5C6CC7N(CCC74c2c1)CC6=CCOC5CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F02 compound treatment 677583.0 220000.0 0.45 660142.0 191000.0 0.41 0.6132 0.999 1982979 ChemDiv1_027920 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccco3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F03 compound treatment 1815059.0 1360000.0 2.8 1971817.0 1500000.0 3.25 4.281 0.9972 1982980 ChemDiv1_027921 CC(=O)C1=NN(C(N1c2ccc(C)cc2)c3c[nH]c4ccccc34)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F04 compound treatment 700961.0 243000.0 0.5 671510.0 203000.0 0.44 0.6647 0.9978 1444389 ChemDiv1_027922 Cc1cccc(c1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F05 compound treatment 717138.0 259000.0 0.53 665582.0 197000.0 0.43 0.6792 0.9936 1285763 ChemDiv1_027923 Cn1c(=O)n(C)c2ncn(Cc3ccc(cc3)C(C)(C)C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F06 compound treatment 700538.0 242000.0 0.5 682504.0 214000.0 0.46 0.6809 0.9992 1982981 ChemDiv1_027924 [O-][N+](=O)c1cc(C2Oc3[nH]c(=S)[nH]c(=O)c23)c(cc1N4CCOCC4)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F07 compound treatment 736013.0 278000.0 0.57 728903.0 260000.0 0.56 0.8037 1.0 1687534 ChemDiv1_027925 Cn1c(=O)n(C)c2nc3n(Cc4ccco4)c(cn3c2c1=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F08 compound treatment 723613.0 266000.0 0.55 683263.0 214000.0 0.46 0.7157 0.9966 1982982 ChemDiv1_027926 CCCCCCC1Oc2ccc(cc2C3OC(c4ccccc4)(c5ccccc5)c6ccccc6N13)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F09 compound treatment 731606.0 274000.0 0.56 748823.0 280000.0 0.61 0.8277 0.9994 1982983 ChemDiv1_027927 FC(F)(F)c1ccccc1NC(=O)Cc2c(Sc3ccccc3)c4ccccc4n2Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F10 compound treatment 666833.0 209000.0 0.43 675557.0 207000.0 0.45 0.6211 0.9998 1982984 ChemDiv1_027928 CCCCOc1cccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F11 compound treatment 718613.0 261000.0 0.54 735228.0 266000.0 0.58 0.788 0.9994 1450767 ChemDiv1_027929 COc1c(Cl)cc(Cl)cc1C=c2sc3nc(c(c4ccccc4)n3c2=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F12 compound treatment 748399.0 290000.0 0.6 704028.0 235000.0 0.51 0.7837 0.9967 1503557 ChemDiv1_027930 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)cc2)C#N)c3ccco3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F13 compound treatment 713322.0 255000.0 0.53 696322.0 227000.0 0.49 0.7207 0.9994 1982985 ChemDiv1_027931 CCCOc1ccc-2c(c1)C(=NNC(=S)N)c3cc(OCCC)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F14 compound treatment 726735.0 269000.0 0.55 706720.0 238000.0 0.51 0.7562 0.9993 1306104 ChemDiv1_027932 Oc1cccc(c1)C(=O)NC2(CCCCC2)C(=O)Nc3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F15 compound treatment 741169.0 283000.0 0.58 754295.0 285000.0 0.62 0.8501 0.9996 1717564 ChemDiv1_027933 Cc1cccc(C)c1NC(=O)C2(CCCCC2)N(Cc3ccccc3)C(=O)CO 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F16 compound treatment 713491.0 255000.0 0.53 725086.0 256000.0 0.55 0.765 0.9997 1982986 ChemDiv1_027934 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(OC(F)(F)F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F17 compound treatment 769230.0 311000.0 0.64 774340.0 305000.0 0.66 0.9217 0.9999 1982987 ChemDiv1_027935 c1ccc(cc1)c2cnc(nn2)c3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F18 compound treatment 714855.0 257000.0 0.53 700761.0 232000.0 0.5 0.7297 0.9996 1728940 ChemDiv1_027936 N#Cc1cc2Oc3cc4ccccc4cc3-c5nnc(c6ccccc6)n5-c2cc1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F19 compound treatment 736732.0 279000.0 0.58 728809.0 260000.0 0.56 0.8046 0.9999 1719711 ChemDiv1_027937 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F20 compound treatment 728155.0 270000.0 0.56 698595.0 230000.0 0.5 0.7458 0.9984 1311059 ChemDiv1_027938 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5cc(C(C)C)c(O)cc5C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F21 compound treatment 737582.0 279000.0 0.58 710894.0 242000.0 0.52 0.7784 0.9988 1942387 ChemDiv1_027939 CCOC(=O)C1(C)C=C(Nc2ccccc2)C(=O)N1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F22 compound treatment 690247.0 232000.0 0.48 678722.0 210000.0 0.45 0.6601 0.9996 1982988 ChemDiv1_027940 OC(C(=O)NNc1cc(Cl)ccc1Cl)(c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F23 mock treatment 671258.0 213000.0 0.44 691681.0 223000.0 0.48 0.6522 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 F24 mock treatment 204459.0 -254000.0 -0.52 173903.0 -295000.0 -0.64 -0.8216 -0.9952 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G01 compound treatment 585280.0 127000.0 0.26 552617.0 83800.0 0.18 0.3139 0.9836 1982989 ChemDiv1_027941 CCCCCCCCN1C(=C)C2(CCCCC2)OC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G02 compound treatment 659271.0 201000.0 0.42 625595.0 157000.0 0.34 0.5336 0.995 1340754 ChemDiv1_027942 CC(=O)NC1CC(C)(C)N(O)C(C)(C)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G03 compound treatment 700792.0 243000.0 0.5 684674.0 216000.0 0.47 0.6846 0.9994 1982990 ChemDiv1_027943 COc1ccc(C2=C/C(=C\3/c4ccccc4-c5ncccc35)/C(=O)O2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G04 compound treatment 693884.0 236000.0 0.49 665542.0 197000.0 0.43 0.6452 0.9978 1314442 ChemDiv1_027944 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccccc4)c5ccc(C#N)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G05 compound treatment 708843.0 251000.0 0.52 679596.0 211000.0 0.46 0.6886 0.998 1982991 ChemDiv1_027945 Cc1ccc(C)c(c1)C2=C/C(=C\3/c4ccccc4-c5ncccc35)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G06 compound treatment 685988.0 228000.0 0.47 661218.0 192000.0 0.42 0.6271 0.9981 1982992 ChemDiv1_027946 CC1(C)Cc2c(ccc3ccccc23)C4=C(C#N)C(=O)C(=O)N41 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G07 compound treatment 713238.0 255000.0 0.53 715204.0 246000.0 0.53 0.7495 1.0 1729993 ChemDiv1_027947 O=c1[nH]c2nc(cn2[nH]c1=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G08 compound treatment 693535.0 235000.0 0.49 683805.0 215000.0 0.47 0.6727 0.9998 1982993 ChemDiv1_027948 OC(=O)CC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccc(O)cc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G09 compound treatment 718827.0 261000.0 0.54 711455.0 243000.0 0.53 0.7519 0.9999 1174096 ChemDiv1_027949 CCOC(=O)c1nc2cc3C(=C(CCC(=O)O)C(C)n3c(C)c2c1C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G10 compound treatment 683398.0 225000.0 0.47 618923.0 150000.0 0.32 0.5586 0.9846 1982994 ChemDiv1_027950 CC1(C)c2ccccc2N3CC(=O)N(Cc4ccccc4)C31/C=C/c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G11 compound treatment 700894.0 243000.0 0.5 700975.0 232000.0 0.5 0.7097 1.0 1516811 ChemDiv1_027951 COc1ccc(cc1OC)c2nn(C3CC(=O)C4OCC3O4)c(=S)n2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G12 compound treatment 697108.0 239000.0 0.49 680329.0 211000.0 0.46 0.6726 0.9993 1982995 ChemDiv1_027952 Cc1c(NC(=O)/C=C/C(=O)O)c(=O)n(C)n1c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G13 compound treatment 733234.0 275000.0 0.57 715665.0 247000.0 0.53 0.7794 0.9995 1982996 ChemDiv1_027953 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccccc3)c4ccc(C)cc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G14 compound treatment 756115.0 298000.0 0.62 741607.0 273000.0 0.59 0.8525 0.9998 1438296 ChemDiv1_027954 CCc1ccc2c3c(CCN4C(=O)OC(C)(C)C42C)c(C)[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G15 compound treatment 735116.0 277000.0 0.57 722448.0 254000.0 0.55 0.7925 0.9998 1982997 ChemDiv1_027955 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3ccc(F)cc3)c4ccccc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G16 compound treatment 734865.0 277000.0 0.57 712059.0 243000.0 0.53 0.7762 0.9992 1682843 ChemDiv1_027956 CC(C)c1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G17 compound treatment 752337.0 294000.0 0.61 692148.0 223000.0 0.48 0.7713 0.9936 1982998 ChemDiv1_027957 CCOC(=O)C1=NN(C(N1C(C)(C)C)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G18 compound treatment 726204.0 268000.0 0.55 713686.0 245000.0 0.53 0.7661 0.9998 1982999 ChemDiv1_027958 CC(=O)Nc1ccc(C=c2sc3nc4cc(Br)cnc4n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G19 compound treatment 757706.0 300000.0 0.62 728969.0 260000.0 0.56 0.8355 0.9989 1435357 ChemDiv1_027959 CC1CC(=O)N(Cc2ccccc2)c3ccccc3N1C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G20 compound treatment 718195.0 260000.0 0.54 688233.0 219000.0 0.47 0.7154 0.9981 1297412 ChemDiv1_027960 Cn1c(=O)n(Cc2ccccc2)c3n(C)c(=O)n(C)c(=O)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G21 compound treatment 772054.0 314000.0 0.65 730194.0 261000.0 0.57 0.8583 0.9977 1983000 ChemDiv1_027961 CCCCSc1ccc2C(=O)c3ccccc3-c4onc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G22 compound treatment 674707.0 217000.0 0.45 671329.0 202000.0 0.44 0.6261 0.9999 1585031 ChemDiv1_027962 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G23 mock treatment 733473.0 275000.0 0.57 687429.0 219000.0 0.47 0.7365 0.9958 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 G24 mock treatment 220093.0 -238000.0 -0.49 239445.0 -229000.0 -0.5 -0.6985 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H01 compound treatment 626883.0 169000.0 0.35 593523.0 125000.0 0.27 0.4372 0.992 1157219 ChemDiv1_027963 Cc1cc(=O)oc2c3c(Nc4ccc(Br)c(Cl)c4)coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H02 compound treatment 647458.0 189000.0 0.39 624725.0 156000.0 0.34 0.515 0.9973 1333393 ChemDiv1_027964 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H03 compound treatment 2164554.0 1710000.0 3.52 2072960.0 1600000.0 3.47 4.9459 1.0 1983001 ChemDiv1_027965 CC(=O)C1=NN(C(N1c2ccc(F)cc2)c3c[nH]c4ccccc34)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H04 compound treatment 673864.0 216000.0 0.45 671034.0 202000.0 0.44 0.6244 1.0 1442707 ChemDiv1_027966 COc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H05 compound treatment 681352.0 223000.0 0.46 676696.0 208000.0 0.45 0.644 0.9999 1284852 ChemDiv1_027967 Cc1ccc(cc1C)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H06 compound treatment 679008.0 221000.0 0.46 658849.0 190000.0 0.41 0.6133 0.9987 1983002 ChemDiv1_027968 Cn1c2OC(c2c(=O)n(C)c1=O)c3cc([N+](=O)[O-])c(cc3N4CCOCC4)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H07 compound treatment 719352.0 261000.0 0.54 684291.0 215000.0 0.47 0.7111 0.9974 1983003 ChemDiv1_027969 O=C(COc1ccccc1)NN=C2CSc3sc(=O)sc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H08 compound treatment 706833.0 249000.0 0.51 704254.0 235000.0 0.51 0.7234 1.0 1983004 ChemDiv1_027970 Oc1ccc(Br)cc1C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H09 compound treatment 746137.0 288000.0 0.59 736682.0 268000.0 0.58 0.8304 0.9999 1983005 ChemDiv1_027971 CCCCOc1cccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3OC)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H10 compound treatment 706838.0 249000.0 0.51 699684.0 231000.0 0.5 0.7164 0.9999 1613280 ChemDiv1_027972 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Oc3ccccc3)cc2)C#N)c4ccccc4)C(=O)Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H11 compound treatment 709045.0 251000.0 0.52 721487.0 253000.0 0.55 0.753 0.9996 1983006 ChemDiv1_027973 [O-][N+](=O)c1ccc(C=c2sc3=NN=C(C(c4ccccc4)n3c2=O)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H12 compound treatment 760483.0 302000.0 0.62 718345.0 249000.0 0.54 0.8233 0.9974 1514468 ChemDiv1_027974 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)cc2C)C#N)c3ccco3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H13 compound treatment 708608.0 251000.0 0.52 689142.0 220000.0 0.48 0.7028 0.9992 1983007 ChemDiv1_027975 CCOc1ccc-2c(c1)C(=NNC(=N)N)c3cc(OCC)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H14 compound treatment 700844.0 243000.0 0.5 712253.0 243000.0 0.53 0.7269 0.9997 1530400 ChemDiv1_027976 CC(Oc1cc(Cl)c(Cl)cc1Cl)C(=O)N(Cc2ccco2)C(C)(C)C(=O)Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H15 compound treatment 731178.0 273000.0 0.56 703171.0 234000.0 0.51 0.7573 0.9986 1983008 ChemDiv1_027977 COc1cccc(NC2(CCCC2)c3nnnn3c4ccccc4C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H16 compound treatment 705335.0 247000.0 0.51 670010.0 201000.0 0.44 0.6688 0.9969 1529281 ChemDiv1_027978 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H17 compound treatment 721363.0 263000.0 0.54 725315.0 256000.0 0.56 0.7768 0.9999 1390725 ChemDiv1_027979 CCc1c(oc2ccc3c(C)cc(=O)oc3c12)C(=O)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H18 compound treatment 688739.0 231000.0 0.48 670698.0 202000.0 0.44 0.6456 0.9991 1536690 ChemDiv1_027980 Cc1cc2NC(=O)CC(c3ccc(Cl)c(Cl)c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H19 compound treatment 729327.0 271000.0 0.56 713765.0 245000.0 0.53 0.7708 0.9996 1524034 ChemDiv1_027981 CCc1c(oc2c(C)c3oc(=O)cc(C)c3cc12)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H20 compound treatment 664085.0 206000.0 0.43 670218.0 201000.0 0.44 0.6089 0.9999 1983009 ChemDiv1_027982 CCCCC(=O)NC(Nc1cc(C)ccn1)(C(=O)OCC)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H21 compound treatment 702021.0 244000.0 0.5 681776.0 213000.0 0.46 0.6819 0.999 1129728 ChemDiv1_027983 CCOc1ccc(cc1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(F)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H22 compound treatment 671118.0 213000.0 0.44 684873.0 216000.0 0.47 0.6416 0.9995 1983010 ChemDiv1_027984 Cc1ccc(cc1)C(O)(C(=O)NN(C(=O)c2cccnc2N3CCCCC3)c4ccccc4)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H23 mock treatment 655755.0 198000.0 0.41 673070.0 204000.0 0.44 0.6011 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 H24 mock treatment 255781.0 -202000.0 -0.42 210501.0 -258000.0 -0.56 -0.6907 -0.9897 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I01 compound treatment 629447.0 171000.0 0.35 570725.0 102000.0 0.22 0.4061 0.9741 1465901 ChemDiv1_027985 CC1(O)N(C2CC(C)(C)NC(C)(C)C2)C(=O)OC31CC(C)(C)NC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I02 compound treatment 657489.0 199000.0 0.41 621110.0 152000.0 0.33 0.5241 0.9939 1445803 ChemDiv1_027986 CC(=O)NC1CC(C)(C)N(OC(=O)C)C(C)(C)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I03 compound treatment 693595.0 236000.0 0.49 664062.0 195000.0 0.42 0.6425 0.9976 1983011 ChemDiv1_027987 COc1ccc(cc1OC)S(=O)(=O)n2nnc3cc(Cl)ccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I04 compound treatment 694738.0 237000.0 0.49 647480.0 179000.0 0.39 0.6188 0.9933 1408664 ChemDiv1_027988 CN1C2NC(=O)N(CCC(=O)O)C2N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I05 compound treatment 711188.0 253000.0 0.52 676794.0 208000.0 0.45 0.6877 0.9972 1983012 ChemDiv1_027989 COc1ccc(cc1)C2=C/C(=C/3\c4ccccc4-c5ncccc35)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I06 compound treatment 699908.0 242000.0 0.5 667110.0 198000.0 0.43 0.6564 0.9972 1983013 ChemDiv1_027990 CSCCC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccc(O)cc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I07 compound treatment 731994.0 274000.0 0.57 687958.0 219000.0 0.47 0.7352 0.9962 1983014 ChemDiv1_027991 COC(=O)C12Nc3ccccc3NC(=C2C(=O)C(=O)N1c4ccc(C)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I08 compound treatment 698934.0 241000.0 0.5 678350.0 210000.0 0.45 0.6722 0.9989 1626763 ChemDiv1_027992 Cc1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccc(C)cc4)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I09 compound treatment 720146.0 262000.0 0.54 682634.0 214000.0 0.46 0.7097 0.997 1319780 ChemDiv1_027993 CCN1C2C(N(CC)C1=O)N(C(=O)C)C(=O)N2C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I10 compound treatment 678321.0 220000.0 0.45 672836.0 204000.0 0.44 0.6337 0.9999 1983015 ChemDiv1_027994 Cc1ccc2N3CC(=O)NC3(/C=C/c4cccnc4)C(C)(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I11 compound treatment 705985.0 248000.0 0.51 677878.0 209000.0 0.45 0.6818 0.9981 1304955 ChemDiv1_027995 Cc1cc2n(Cc3ccccc3Cl)c(=S)n(C4CC(=O)C5OCC4O5)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I12 compound treatment 690987.0 233000.0 0.48 679697.0 211000.0 0.46 0.6627 0.9997 1983016 ChemDiv1_027996 Cc1cc2CC(C)(C)N/C(=N\c3ccc(Cl)cc3)/c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I13 compound treatment 691597.0 234000.0 0.48 687283.0 218000.0 0.47 0.6752 1.0 1983017 ChemDiv1_027997 CC(=O)N1N=C(OC1c2ccc(C)cc2)c3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I14 compound treatment 724732.0 267000.0 0.55 708603.0 240000.0 0.52 0.7562 0.9996 1199842 ChemDiv1_027998 CCN1CCCC(C1)N2C(=O)OC(C)(C)C2(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I15 compound treatment 766474.0 308000.0 0.64 718318.0 249000.0 0.54 0.832 0.9966 1778622 ChemDiv1_027999 Oc1cccc(c1)c2nc(c([nH]2)c3ccccc3)c4ccc(cc4)c5ccc(cc5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I16 compound treatment 721093.0 263000.0 0.54 703592.0 235000.0 0.51 0.7432 0.9995 1983018 ChemDiv1_028000 COc1ccc(cc1)C(O)(C(=O)NNc2cccc(Cl)c2)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I17 compound treatment 764313.0 306000.0 0.63 729597.0 261000.0 0.56 0.8461 0.9984 1983019 ChemDiv1_028001 CCOC(=O)C1=C(N)n2c(=O)c(=Cc3ccc4OCOc4c3)sc2=C(C1c5ccc6OCOc6c5)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I18 compound treatment 716457.0 258000.0 0.53 687655.0 219000.0 0.47 0.712 0.9982 1128714 ChemDiv1_028002 CC1(C)CC(CC(C)(C)N1)NCCC(=O)NC2CC(C)(C)NC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I19 compound treatment 739243.0 281000.0 0.58 675142.0 206000.0 0.45 0.7261 0.9916 1267731 ChemDiv1_028003 CC(=O)N1C(CC(=O)N(Cc2ccccc2)c3ccccc13)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I20 compound treatment 730514.0 272000.0 0.56 675610.0 207000.0 0.45 0.7141 0.9936 1983020 ChemDiv1_028004 CSC1=NC2(CC(c3ccccc3)c4cc(Cl)c(O)cc4O2)CC(C)(C)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I21 compound treatment 732877.0 275000.0 0.57 729553.0 261000.0 0.56 0.8001 1.0 1720372 ChemDiv1_028005 Cc1cc(C)c(C(=O)C2=C(O)C(=O)N(C2c3cccnc3)c4ccccn4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I22 compound treatment 700233.0 242000.0 0.5 691725.0 223000.0 0.48 0.6946 0.9998 1482149 ChemDiv1_028006 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccc(C)c(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I23 mock treatment 700024.0 242000.0 0.5 678822.0 210000.0 0.45 0.6745 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 I24 mock treatment 238094.0 -220000.0 -0.45 207454.0 -261000.0 -0.57 -0.7212 -0.9941 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J01 compound treatment 637257.0 179000.0 0.37 597909.0 129000.0 0.28 0.4591 0.9904 1983021 ChemDiv1_028007 CCCCCCC(=O)OC1CC[C@]2(C)C3CC[C@@]4(C)C(CCC4=O)C3CC=C2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J02 compound treatment 639080.0 181000.0 0.37 613100.0 144000.0 0.31 0.485 0.996 1466621 ChemDiv1_028008 CCC1OC(=Nc2ccccc12)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J03 compound treatment 924244.0 466000.0 0.96 1062990.0 594000.0 1.29 1.5898 0.9898 1983022 ChemDiv1_028009 COc1cccc(C2N(N=C(N2c3ccc(C)c(C)c3)C(=O)C)c4ccccc4)c1OCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J04 compound treatment 675264.0 217000.0 0.45 650557.0 182000.0 0.39 0.5951 0.9979 1983023 ChemDiv1_028010 CCCCCCCCOc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J05 compound treatment 659880.0 202000.0 0.42 708057.0 239000.0 0.52 0.6607 0.9942 1983024 ChemDiv1_028011 COC(=O)C1(N=C(OC(=N1)c2ccc(Cl)cc2)N3CCOCC3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J06 compound treatment 664853.0 207000.0 0.43 677307.0 208000.0 0.45 0.6209 0.9996 1983025 ChemDiv1_028012 Cc1ccc(C2=Nc3ccccc3N=C(C2)c4cccc(Br)c4)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J07 compound treatment 677678.0 220000.0 0.45 691210.0 222000.0 0.48 0.6609 0.9996 1983026 ChemDiv1_028013 CC1(C)CC2(CC(c3ccccc3)c4ccc(O)c(O)c4O2)NC(=N1)SCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J08 compound treatment 688940.0 231000.0 0.48 688169.0 219000.0 0.47 0.6726 1.0 1983027 ChemDiv1_028014 COc1ccccc1C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J09 compound treatment 702072.0 244000.0 0.5 753100.0 284000.0 0.62 0.7912 0.9951 1873297 ChemDiv1_028015 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccc(I)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J10 compound treatment 684465.0 226000.0 0.47 698738.0 230000.0 0.5 0.6823 0.9995 1333155 ChemDiv1_028016 COc1cccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J11 compound treatment 686344.0 228000.0 0.47 678631.0 210000.0 0.45 0.6543 0.9998 1134338 ChemDiv1_028017 COc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J12 compound treatment 712758.0 255000.0 0.53 765168.0 296000.0 0.64 0.8252 0.9951 1983028 ChemDiv1_028018 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Cl)cc2)C#N)c3ccco3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J13 compound treatment 744387.0 286000.0 0.59 714278.0 245000.0 0.53 0.7935 0.9986 1983029 ChemDiv1_028019 COC(=O)c1ccc(C=c2sc3nnc(c4ccccc4)n3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J14 compound treatment 700441.0 242000.0 0.5 732482.0 264000.0 0.57 0.7572 0.9979 1719094 ChemDiv1_028020 CC(Oc1cc(Cl)c(Cl)cc1Cl)C(=O)N(Cc2ccccc2)C(C)(C)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J15 compound treatment 712406.0 254000.0 0.53 687277.0 218000.0 0.47 0.7055 0.9986 1983030 ChemDiv1_028021 CCC(C)(NC)c1nnnn1c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J16 compound treatment 797142.0 339000.0 0.7 832630.0 364000.0 0.79 1.0517 0.9983 1212415 ChemDiv1_028022 COc1cccc(c1)c2cn3nc(C)c(C)nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J17 compound treatment 715745.0 258000.0 0.53 731661.0 263000.0 0.57 0.7783 0.9994 1983031 ChemDiv1_028023 Nc1ccc2N3C4C5C6CC7N(CCC74c2c1)CC6=CCOC5CC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J18 compound treatment 702128.0 244000.0 0.5 718430.0 250000.0 0.54 0.7382 0.9994 1983032 ChemDiv1_028024 COc1cc2CC(C)(C)N=C(Nc3ccc(Cl)cc3Cl)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J19 compound treatment 760261.0 302000.0 0.62 763093.0 294000.0 0.64 0.8914 0.9999 1983033 ChemDiv1_028025 CCC1C/C(=C\c2ccc(OCC(=O)N)cc2)/C(=O)\C(=C\c3ccc(OCC(=O)N)cc3)\C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J20 compound treatment 700365.0 242000.0 0.5 711147.0 242000.0 0.52 0.7245 0.9997 1983034 ChemDiv1_028026 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)CCCN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J21 compound treatment 727655.0 270000.0 0.56 743143.0 274000.0 0.59 0.8133 0.9995 1707284 ChemDiv1_028027 Cc1[nH]c2ccc(Cl)c3c2c1CCN4C(=O)OC(C)(C)C43C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J22 compound treatment 690860.0 233000.0 0.48 701653.0 233000.0 0.5 0.6961 0.9997 1983035 ChemDiv1_028028 COc1ccccc1N(NC(=O)C(O)(c2ccc(F)cc2)c3ccc(F)cc3)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J23 mock treatment 676956.0 219000.0 0.45 692604.0 224000.0 0.48 0.6619 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 J24 mock treatment 219936.0 -238000.0 -0.49 246115.0 -223000.0 -0.48 -0.6885 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K01 compound treatment 822727.0 365000.0 0.75 763752.0 295000.0 0.64 0.9836 0.9966 1275551 ChemDiv1_028029 CCCS(=O)(=O)c1c(C(=O)c2ccc(OC)c(OC)c2)n3cccc(N)c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K02 compound treatment 692743.0 235000.0 0.48 618035.0 149000.0 0.32 0.5709 0.9806 1983036 ChemDiv1_028030 NC(=O)CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3[N+](=O)[O-])c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K03 compound treatment 700131.0 242000.0 0.5 654811.0 186000.0 0.4 0.6379 0.9942 1782953 ChemDiv1_028031 Cc1ncc([N+](=O)[O-])n1S(=O)(=O)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K04 compound treatment 754796.0 297000.0 0.61 705206.0 236000.0 0.51 0.7948 0.996 1333463 ChemDiv1_028032 CC1CCC2(CC1)NC(=S)c3c4CCC(C)Cc4sc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K05 compound treatment 705278.0 247000.0 0.51 650640.0 182000.0 0.39 0.639 0.9917 1649733 ChemDiv1_028033 OC1=C(C(N(C1=O)c2ccccn2)c3cccnc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K06 compound treatment 679903.0 222000.0 0.46 648789.0 180000.0 0.39 0.5992 0.9968 1983037 ChemDiv1_028034 CCN1C(=O)C2C(NC(CCSC)(C2C1=O)C(=O)O)c3ccccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K07 compound treatment 706699.0 249000.0 0.51 685461.0 217000.0 0.47 0.6944 0.999 1983038 ChemDiv1_028035 COC(=O)C12Sc3ccccc3NC(=C2C(=O)C(=O)N1c4ccccc4)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K08 compound treatment 715597.0 258000.0 0.53 678860.0 210000.0 0.45 0.6973 0.997 1335709 ChemDiv1_028036 Oc1ccc(cc1)C2N(C(=O)c3[nH]nc(c23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K09 compound treatment 713143.0 255000.0 0.53 676571.0 208000.0 0.45 0.6902 0.9969 1983039 ChemDiv1_028037 Cc1cc2CSC(SCc2cc1C)c3c(O)ccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K10 compound treatment 710073.0 252000.0 0.52 666557.0 198000.0 0.43 0.6704 0.9953 1983040 ChemDiv1_028038 Cc1ccc(cc1)N2C(=N/C(=N\c3cccc(C)c3)/C42CCCC4)SCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K11 compound treatment 723602.0 266000.0 0.55 699634.0 231000.0 0.5 0.7408 0.9989 1318701 ChemDiv1_028039 Clc1ccc(c2nn(C3CC(=O)C4OCC3O4)c(=S)n2CC=C)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K12 compound treatment 685661.0 228000.0 0.47 632106.0 163000.0 0.35 0.582 0.9901 1983041 ChemDiv1_028040 CC1(C)c2ccccc2N3CC(=O)NC31/C=C/c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K13 compound treatment 739470.0 281000.0 0.58 706011.0 237000.0 0.51 0.7737 0.9981 1120604 ChemDiv1_028041 Cc1cc(N2CCN(CC2)c3ncccn3)n4c5ccccc5nc4c1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K14 compound treatment 694128.0 236000.0 0.49 685412.0 217000.0 0.47 0.676 0.9998 1371062 ChemDiv1_028042 Clc1ccccc1C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K15 compound treatment 725686.0 268000.0 0.55 699238.0 230000.0 0.5 0.7432 0.9987 1943194 ChemDiv1_028043 CCOC(=O)C1=CS/C(=C\2/C(=S)C(C)(C)Nc3ccc(C)cc23)/S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K16 compound treatment 735340.0 277000.0 0.57 675629.0 207000.0 0.45 0.7212 0.9926 1983042 ChemDiv1_028044 OC(C(=O)NN(C(=O)c1ccco1)c2cccc(Cl)c2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K17 compound treatment 749352.0 291000.0 0.6 699081.0 230000.0 0.5 0.7775 0.9956 1983043 ChemDiv1_028045 CC(O)(/C=C\1/Oc2ccc(cc2C1N3CCOCC3)[N+](=O)[O-])C4CC5CC4C=C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K18 compound treatment 720163.0 262000.0 0.54 674547.0 206000.0 0.45 0.6974 0.9953 1309122 ChemDiv1_028046 COC(=O)CCC1(CCC(=O)OC)C(=O)CC(C)(C)CC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K19 compound treatment 741419.0 283000.0 0.58 701455.0 233000.0 0.5 0.7696 0.9972 1411006 ChemDiv1_028047 Cc1cc(=O)oc2c3c(Nc4cccc5ccccc45)coc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K20 compound treatment 720942.0 263000.0 0.54 686334.0 217000.0 0.47 0.7165 0.9975 1983044 ChemDiv1_028048 CC1(C)CC2(CC(c3ccccc3)c4cc(Cl)c(O)cc4O2)N=C(N1)SCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K21 compound treatment 735228.0 277000.0 0.57 712217.0 243000.0 0.53 0.777 0.9991 1433340 ChemDiv1_028049 Clc1ccc(cc1)c2nc(N3CCCCC3)c4oc5ccccc5c4n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K22 compound treatment 701292.0 243000.0 0.5 668775.0 200000.0 0.43 0.661 0.9973 1420283 ChemDiv1_028050 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3OC)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K23 mock treatment 685744.0 228000.0 0.47 675619.0 207000.0 0.45 0.6488 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 K24 mock treatment 221350.0 -237000.0 -0.49 228408.0 -240000.0 -0.52 -0.7135 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L01 compound treatment 638695.0 181000.0 0.37 593884.0 125000.0 0.27 0.455 0.9876 1983045 ChemDiv1_028051 CC(C)CC1(C)NN(C(=S)N1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L02 compound treatment 658111.0 200000.0 0.41 639723.0 171000.0 0.37 0.5535 0.9985 1983046 ChemDiv1_028052 CCCCCCCCOc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L03 compound treatment 703357.0 245000.0 0.51 723542.0 255000.0 0.55 0.7478 0.9991 1983047 ChemDiv1_028053 CCOC(=O)C1=NN(C(N1c2ccc(C)cc2)c3c[nH]c4ccccc34)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L04 compound treatment 674114.0 216000.0 0.45 668501.0 200000.0 0.43 0.6209 0.9999 1210050 ChemDiv1_028054 Cn1c(=O)n(C)c2nc3n(Cc4ccco4)c(cn3c2c1=O)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L05 compound treatment 667257.0 209000.0 0.43 683689.0 215000.0 0.46 0.6341 0.9993 1362773 ChemDiv1_028055 CCC1(C(c2ccccc2)C1(C(=O)OC)C(=O)OC)C(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L06 compound treatment 697913.0 240000.0 0.5 676002.0 207000.0 0.45 0.6671 0.9988 1412384 ChemDiv1_028056 Brc1ccc(cc1)C2=Nc3ccccc3N(C(C2)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L07 compound treatment 698990.0 241000.0 0.5 660223.0 191000.0 0.41 0.6445 0.9959 1983048 ChemDiv1_028057 COc1cc2CC3(CCCC3)N=C(Nn4cnnc4)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L08 compound treatment 672277.0 214000.0 0.44 671552.0 203000.0 0.44 0.6229 1.0 1983049 ChemDiv1_028058 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L09 compound treatment 694668.0 237000.0 0.49 709118.0 240000.0 0.52 0.7131 0.9995 1522739 ChemDiv1_028059 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L10 compound treatment 674939.0 217000.0 0.45 673968.0 205000.0 0.44 0.6305 1.0 1184125 ChemDiv1_028060 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L11 compound treatment 708874.0 251000.0 0.52 724265.0 255000.0 0.55 0.757 0.9995 1983050 ChemDiv1_028061 FC(F)(F)c1cccc(c1)N2NC3(CCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L12 compound treatment 678951.0 221000.0 0.46 687411.0 219000.0 0.47 0.6569 0.9998 1573881 ChemDiv1_028062 CC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L13 compound treatment 677326.0 219000.0 0.45 659636.0 191000.0 0.41 0.612 0.999 1983051 ChemDiv1_028063 CCCCCC1(C)NN(C(=S)N1)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L14 compound treatment 701756.0 244000.0 0.5 720049.0 251000.0 0.54 0.7401 0.9992 1983052 ChemDiv1_028064 CNC(C)(C)c1nnnn1c2c(C)cccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L15 compound treatment 710790.0 253000.0 0.52 716393.0 248000.0 0.54 0.7477 0.9999 1983053 ChemDiv1_028065 FC(F)(F)c1cccc(c1)n2nnnc2C3(CCCCC3)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L16 compound treatment 773391.0 315000.0 0.65 792222.0 323000.0 0.7 0.9552 0.9993 1342226 ChemDiv1_028066 COc1cccc(c1)c2cn3nc4CCCCc4nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L17 compound treatment 706203.0 248000.0 0.51 728441.0 260000.0 0.56 0.7595 0.9989 1983054 ChemDiv1_028067 C1C=C[C@@H]2[C@H]1[C@@H](Nc3ccc(cc23)[C@]4(C[C@@H]5CC6C[C@@H](C5)C4)C6)c7cccnc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L18 compound treatment 703325.0 245000.0 0.51 695765.0 227000.0 0.49 0.7053 0.9999 1983055 ChemDiv1_028068 COc1cc2CC(C)(C)N=C(C3=NC(C)(C)Cc4cc(OC)c(OC)cc34)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L19 compound treatment 717085.0 259000.0 0.53 701985.0 233000.0 0.5 0.7349 0.9996 1983056 ChemDiv1_028069 CCCCC1(CC)NN(C(=S)N1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L20 compound treatment 680709.0 223000.0 0.46 706978.0 238000.0 0.52 0.6894 0.9984 1983057 ChemDiv1_028070 COc1cc(cc(OC)c1OC)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L21 compound treatment 738689.0 281000.0 0.58 805774.0 337000.0 0.73 0.9252 0.9935 1202791 ChemDiv1_028071 Cc1[nH]c2c(Br)ccc3c2c1CCN4C(=O)OC(C)(C)C43C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L22 compound treatment 681536.0 223000.0 0.46 698454.0 230000.0 0.5 0.6776 0.9993 1983058 ChemDiv1_028072 COc1ccccc1N(NC(=O)C(O)(c2ccccc2OC)c3ccccc3OC)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L23 mock treatment 684999.0 227000.0 0.47 696926.0 228000.0 0.49 0.6803 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 L24 mock treatment 283782.0 -174000.0 -0.36 242743.0 -226000.0 -0.49 -0.6005 -0.9886 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M01 compound treatment 640828.0 183000.0 0.38 571739.0 103000.0 0.22 0.4242 0.9684 1983059 ChemDiv1_028073 Clc1ccc(cc1)C2=NCCNC3=C2C(N(C3=O)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M02 compound treatment 688773.0 231000.0 0.48 610621.0 142000.0 0.31 0.5537 0.9774 1714847 ChemDiv1_028074 CCOc1ccc(cc1)n2c(n[nH]c2=S)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M03 compound treatment 694124.0 236000.0 0.49 671086.0 202000.0 0.44 0.6541 0.9986 1983060 ChemDiv1_028075 Cc1ccc(I)cc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M04 compound treatment 672343.0 214000.0 0.44 641915.0 173000.0 0.37 0.5776 0.9966 1983061 ChemDiv1_028076 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M05 compound treatment 692604.0 235000.0 0.48 669410.0 201000.0 0.43 0.6493 0.9985 1639303 ChemDiv1_028077 OC1=C(C(N(C1=O)c2ccccn2)c3cccnc3)C(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M06 compound treatment 683210.0 225000.0 0.46 660616.0 192000.0 0.42 0.6221 0.9984 1741115 ChemDiv1_028078 COc1ccc(cc1)C2(CC(NC(=S)N2)c3ccccc3Cl)c4ccc(O)cc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M07 compound treatment 714415.0 256000.0 0.53 699411.0 231000.0 0.5 0.727 0.9996 1983062 ChemDiv1_028079 CCOc1ccc(cc1)N2C(=O)C(=C(C(=O)c3ccccc3)C2(Nc4cccc(c4)C(F)(F)F)C(=O)OC)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M08 compound treatment 747303.0 289000.0 0.6 710554.0 242000.0 0.52 0.7921 0.9978 1700656 ChemDiv1_028080 Clc1ccc(cc1)c2cn3nc(c4ccccc4)c(nc3n2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M09 compound treatment 708646.0 251000.0 0.52 672587.0 204000.0 0.44 0.6776 0.9968 1360232 ChemDiv1_028081 Cn1c(=O)n(C)c2ncn(CC(=O)c3ccccc3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M10 compound treatment 698702.0 241000.0 0.5 625712.0 157000.0 0.34 0.5913 0.9828 1477786 ChemDiv1_028082 O=C1NC2NC(=O)N(C2N1)C3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M11 compound treatment 724423.0 266000.0 0.55 688165.0 219000.0 0.47 0.7244 0.9973 1164850 ChemDiv1_028083 CCC(=O)Nc1ccc2OCCOc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M12 compound treatment 652143.0 194000.0 0.4 576129.0 107000.0 0.23 0.4475 0.9664 1983063 ChemDiv1_028084 CC1(C)c2ccccc2N3CCC(=O)NC31/C=C/c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M13 compound treatment 711156.0 253000.0 0.52 678832.0 210000.0 0.45 0.6908 0.9976 1665953 ChemDiv1_028085 CC(C)(C)NCC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M14 compound treatment 730061.0 272000.0 0.56 687924.0 219000.0 0.47 0.7323 0.9965 1678697 ChemDiv1_028086 OC(=O)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M15 compound treatment 738096.0 280000.0 0.58 707590.0 239000.0 0.52 0.7741 0.9984 1983064 ChemDiv1_028087 COc1ccccc1C2N(C(=O)C(=C2C(=O)c3ccc(Br)cc3)O)c4cccc(c4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M16 compound treatment 709494.0 251000.0 0.52 669205.0 200000.0 0.43 0.6736 0.996 1632452 ChemDiv1_028088 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M17 compound treatment 754885.0 297000.0 0.61 667936.0 199000.0 0.43 0.7379 0.9852 1550752 ChemDiv1_028089 CC(=O)N1C(CC(=O)Nc2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M18 compound treatment 688414.0 230000.0 0.48 675577.0 207000.0 0.45 0.6526 0.9995 1686344 ChemDiv1_028090 COc1ccc(C2Nc3ccc4ncccc4c3C5=C2C(=O)CC(C)(C)C5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M19 compound treatment 752291.0 294000.0 0.61 729415.0 261000.0 0.56 0.8282 0.9993 1741274 ChemDiv1_028091 CCC1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(Cl)c(c5)C(=O)O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M20 compound treatment 694414.0 236000.0 0.49 659415.0 191000.0 0.41 0.6366 0.9965 1983065 ChemDiv1_028092 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2ccc(Br)cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M21 compound treatment 714009.0 256000.0 0.53 708178.0 239000.0 0.52 0.7399 1.0 1377782 ChemDiv1_028093 COc1ccc(C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M22 compound treatment 691884.0 234000.0 0.48 696262.0 227000.0 0.49 0.6893 1.0 1378778 ChemDiv1_028094 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccccc3)SCC(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M23 mock treatment 672601.0 215000.0 0.44 690943.0 222000.0 0.48 0.653 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 M24 mock treatment 207936.0 -250000.0 -0.52 454009.0 -14800.0 -0.03 -0.3878 -0.7496 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N01 compound treatment 639194.0 181000.0 0.37 591816.0 123000.0 0.27 0.4526 0.9861 1641634 ChemDiv1_028095 CCCCC1(C)NN(C(=S)N1)c2cccc(C)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N02 compound treatment 654563.0 196000.0 0.41 634637.0 166000.0 0.36 0.5405 0.9981 1444970 ChemDiv1_028096 COc1ccccc1Cn2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N03 compound treatment 662721.0 205000.0 0.42 680704.0 212000.0 0.46 0.6229 0.9992 1983066 ChemDiv1_028097 CCOC(=O)C1=NN(C(N1c2ccc(C)cc2)c3c[nH]c4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N04 compound treatment 673474.0 215000.0 0.44 639237.0 170000.0 0.37 0.5752 0.9957 1983067 ChemDiv1_028098 CCCCCCOc1cccc(c1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N05 compound treatment 678741.0 221000.0 0.46 685909.0 217000.0 0.47 0.6543 0.9999 1548947 ChemDiv1_028099 Cc1cccc2c(Sc3ccccc3)c(CC(=O)Nc4ccccc4)n(Cc5ccccc5)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N06 compound treatment 656232.0 198000.0 0.41 651101.0 182000.0 0.39 0.5682 0.9998 1350420 ChemDiv1_028100 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(Cl)c2C)C#N)c3ccco3)C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N07 compound treatment 687767.0 230000.0 0.47 672282.0 203000.0 0.44 0.6466 0.9993 1983068 ChemDiv1_028101 COc1cc2CC(C)(C)N=C(C(Cl)Cl)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N08 compound treatment 661831.0 204000.0 0.42 677240.0 208000.0 0.45 0.6163 0.9994 1983069 ChemDiv1_028102 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4cc(Br)cc5cccnc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N09 compound treatment 655528.0 197000.0 0.41 688768.0 220000.0 0.48 0.6248 0.997 1130377 ChemDiv1_028103 N#Cc1cc2Oc3ccccc3-c4nnc(c5ccccc5)n4-c2cc1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N10 compound treatment 688542.0 230000.0 0.48 675114.0 206000.0 0.45 0.6521 0.9995 1983070 ChemDiv1_028104 CCCCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)Nc3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N11 compound treatment 821173.0 363000.0 0.75 818298.0 349000.0 0.76 1.0648 1.0 1983071 ChemDiv1_028105 CC(=O)C1=NN(C(N1c2ccc(F)cc2)c3cccc(OCc4ccc(Cl)cc4)c3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N12 compound treatment 646950.0 189000.0 0.39 650806.0 182000.0 0.39 0.5542 1.0 1484857 ChemDiv1_028106 OC(CNC1CC1)Cn2c3ccccc3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N13 compound treatment 670540.0 212000.0 0.44 700670.0 232000.0 0.5 0.6649 0.9978 1983072 ChemDiv1_028107 Clc1ccc(cc1)N2NC3(CCCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N14 compound treatment 671160.0 213000.0 0.44 726550.0 258000.0 0.56 0.7054 0.9931 1983073 ChemDiv1_028108 COc1cccc(NC2(CCCC2)c3nnnn3c4ccc(C)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N15 compound treatment 666750.0 209000.0 0.43 719910.0 251000.0 0.54 0.6888 0.9934 1983074 ChemDiv1_028109 CN(O)C1(CCCCC1)c2nnnn2c3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N16 compound treatment 678517.0 220000.0 0.46 707771.0 239000.0 0.52 0.6874 0.998 1983075 ChemDiv1_028110 OC(C(=O)NNc1cccc2ccccc12)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N17 compound treatment 4251195.0 3790000.0 7.83 4609808.0 4140000.0 8.96 11.8743 0.9977 1322666 ChemDiv1_028111 Nc1c2-c3ccccc3C(=O)c4c(Cl)ccc([nH]c1=O)c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N18 compound treatment 674311.0 216000.0 0.45 693107.0 224000.0 0.49 0.6588 0.9991 1983076 ChemDiv1_028112 CC1(C)Cc2ccccc2/C(=C/[N+](=O)[O-])/N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N19 compound treatment 1227727.0 770000.0 1.59 1363205.0 894000.0 1.94 2.4922 0.9952 1983077 ChemDiv1_028113 COc1cccc(C2N(N=C(N2c3cccc(C)c3)C(=O)C)c4ccc(C)cc4)c1OCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N20 compound treatment 663363.0 205000.0 0.42 692858.0 224000.0 0.48 0.6425 0.9977 1983078 ChemDiv1_028114 CC(CC=C(c1ccccc1)c2ccccc2)C3CCC4C5CCC6CC(CCC6(C)C5C[C@H](OC(=O)C)C34C)OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N21 compound treatment 694718.0 237000.0 0.49 687880.0 219000.0 0.47 0.6806 0.9999 1934551 ChemDiv1_028115 Cc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N22 compound treatment 661863.0 204000.0 0.42 711198.0 242000.0 0.52 0.6684 0.994 1983079 ChemDiv1_028116 OC(C(=O)N(/N=C/c1ccccc1)c2ccccc2)(c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N23 mock treatment 644306.0 186000.0 0.38 666806.0 198000.0 0.43 0.5748 0.9985 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 N24 mock treatment 377671.0 -80400.0 -0.17 478105.0 9260.0 0.02 -0.1032 -0.6173 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O01 compound treatment 650499.0 192000.0 0.4 573592.0 105000.0 0.23 0.4412 0.9646 1983080 ChemDiv1_028117 COc1ccc(I)cc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O02 compound treatment 663026.0 205000.0 0.42 602377.0 134000.0 0.29 0.5035 0.9827 1657728 ChemDiv1_028118 COc1cc(cc(OC)c1O)c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O03 compound treatment 700726.0 243000.0 0.5 627274.0 158000.0 0.34 0.5966 0.9829 1983081 ChemDiv1_028119 Cc1ccc(C)c(c1)S(=O)(=O)n2nnc3cc(Cl)ccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O04 compound treatment 831926.0 374000.0 0.77 799698.0 331000.0 0.72 1.052 0.9993 1983082 ChemDiv1_028120 COc1ccc(/C=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O05 compound treatment 716032.0 258000.0 0.53 657493.0 189000.0 0.41 0.6652 0.9914 1983083 ChemDiv1_028121 CN1C(=O)N(C)C2(N=c3sc(=C/C=C\c4ccc(o4)[N+](=O)[O-])c(=O)n3NC12c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O06 compound treatment 678140.0 220000.0 0.45 619011.0 150000.0 0.33 0.551 0.9865 1269524 ChemDiv1_028122 COc1ccc(Nc2nc3nonc3n4cnnc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O07 compound treatment 881445.0 423000.0 0.87 826299.0 357000.0 0.77 1.165 0.9982 1983084 ChemDiv1_028123 COc1cc(C=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O08 compound treatment 764683.0 307000.0 0.63 702828.0 234000.0 0.51 0.8056 0.9939 1983085 ChemDiv1_028124 Cc1nc2nc(cn2nc1C)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O09 compound treatment 683897.0 226000.0 0.47 659578.0 191000.0 0.41 0.6215 0.9982 1296500 ChemDiv1_028125 OC(=O)c1ccc(Cl)c(c1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O10 compound treatment 663336.0 205000.0 0.42 627858.0 159000.0 0.34 0.543 0.9947 1983086 ChemDiv1_028126 CN1C2NNC(=S)N(C)C2N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O11 compound treatment 648019.0 190000.0 0.39 620638.0 152000.0 0.33 0.5096 0.9961 1656516 ChemDiv1_028127 COc1ccc(cc1)C2Sc3ccccc3N=C4C2=C(O)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O12 compound treatment 663938.0 206000.0 0.42 632488.0 164000.0 0.35 0.5509 0.9959 1983087 ChemDiv1_028128 COc1ccc2CC3N(C)CCc4c(OC)c(OC)c(OC)c(Oc5cc6C(Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O13 compound treatment 680877.0 223000.0 0.46 636631.0 168000.0 0.36 0.582 0.9932 1946077 ChemDiv1_028129 [O-][N+](=O)c1c(N2CCN(CC2)c3ccccn3)c4ccccc4n(c5ccccc5)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O14 compound treatment 678589.0 221000.0 0.46 667770.0 199000.0 0.43 0.6263 0.9996 1702208 ChemDiv1_028130 NC1=C(c2nc(cs2)c3ccccc3)C4(CCCCC4)C(=C(N1)SCC(=O)Nc5ccccc5)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O15 compound treatment 676580.0 218000.0 0.45 670493.0 202000.0 0.44 0.6275 0.9999 1983088 ChemDiv1_028131 Cn1c(=O)c([N+](=O)[O-])c(Nc2ccc(Cl)cc2)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O16 compound treatment 803674.0 346000.0 0.71 813003.0 344000.0 0.74 1.0312 0.9998 1281586 ChemDiv1_028132 Cc1ccc(cc1)c2cn3nc(c4ccccc4)c(nc3n2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O17 compound treatment 703792.0 246000.0 0.51 690725.0 222000.0 0.48 0.6982 0.9996 1139195 ChemDiv1_028133 Clc1ccc(C(=O)N2CCC(=O)Nc3ccccc23)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O18 compound treatment 652951.0 195000.0 0.4 649637.0 181000.0 0.39 0.5611 0.9999 1484121 ChemDiv1_028134 OCCN(CCO)c1nc(nc2c3ccccc3oc12)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O19 compound treatment 689502.0 231000.0 0.48 677208.0 208000.0 0.45 0.6567 0.9996 1983089 ChemDiv1_028135 Cc1ccc(NC2=C(CC(=O)O)C(N(C2=O)c3ccc(C)cc3)c4ccc(Br)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O20 compound treatment 657475.0 199000.0 0.41 663710.0 195000.0 0.42 0.5893 0.9999 1983090 ChemDiv1_028136 CCOC(=O)C/1(C)N(C(=O)C(=O)\C1=N\Nc2cccc(Cl)c2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O21 compound treatment 682321.0 224000.0 0.46 676529.0 208000.0 0.45 0.6452 0.9999 1661638 ChemDiv1_028137 COc1cc(cc(OC)c1OC)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O22 compound treatment 694308.0 236000.0 0.49 719170.0 250000.0 0.54 0.7279 0.9986 1681641 ChemDiv1_028138 COc1ccc(cc1)c2nc3ncc(nn3c2C)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O23 mock treatment 661681.0 204000.0 0.42 656714.0 188000.0 0.41 0.5847 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 O24 mock treatment 227895.0 -230000.0 -0.48 412814.0 -56000.0 -0.12 -0.4218 -0.86 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P01 compound treatment 609291.0 151000.0 0.31 568530.0 99700.0 0.22 0.3733 0.9837 1983091 ChemDiv1_028139 CCOc1ccc(cc1)c2nnc3sc(=Cc4ccc(Cl)cc4)c(=O)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P02 compound treatment 632118.0 174000.0 0.36 582503.0 114000.0 0.25 0.428 0.9829 1508511 ChemDiv1_028140 Cn1c(=O)n(C)c2nc3n(Cc4ccc5OCOc5c4)c(cn3c2c1=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P03 compound treatment 660747.0 203000.0 0.42 621294.0 152000.0 0.33 0.5291 0.9931 1983092 ChemDiv1_028141 CCOC(=O)C1=NN(C(N1c2ccc(OC)cc2)c3c[nH]c4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P04 compound treatment 637800.0 180000.0 0.37 580509.0 112000.0 0.24 0.4332 0.9784 1249451 ChemDiv1_028142 Clc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P05 compound treatment 620710.0 163000.0 0.34 596767.0 128000.0 0.28 0.4332 0.9954 1484939 ChemDiv1_028143 Cc1ccc(cc1Br)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P06 compound treatment 656688.0 199000.0 0.41 603650.0 135000.0 0.29 0.4962 0.9861 1983093 ChemDiv1_028144 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Cl)c(Cl)c2)C#N)c3ccco3)C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P07 compound treatment 632707.0 175000.0 0.36 604062.0 135000.0 0.29 0.4618 0.9947 1983094 ChemDiv1_028145 COc1cc2CC(C)(C)N=C(CCCCl)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P08 compound treatment 636777.0 179000.0 0.37 614611.0 146000.0 0.32 0.4839 0.997 1983095 ChemDiv1_028146 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccc(N=Nc5ccccc5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P09 compound treatment 660639.0 203000.0 0.42 591663.0 123000.0 0.27 0.4836 0.9761 1983096 ChemDiv1_028147 O=C(Nc1ccc2-c3ccc(NC(=O)c4cccs4)cc3S(=O)(=O)c2c1)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P10 compound treatment 631134.0 173000.0 0.36 611638.0 143000.0 0.31 0.4711 0.9974 1656653 ChemDiv1_028148 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Cl)cc2)C#N)c3ccco3)C(=O)Nc4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P11 compound treatment 633138.0 175000.0 0.36 592008.0 123000.0 0.27 0.444 0.9888 1983097 ChemDiv1_028149 CN(C)c1ccc(/C=N/NC(=O)CN2C(=O)CN=C(c3ccccc3)c4cc(Br)ccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P12 compound treatment 620590.0 163000.0 0.34 637446.0 169000.0 0.36 0.4952 0.9991 1983098 ChemDiv1_028150 FC(F)(F)c1cccc(c1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P13 compound treatment 617608.0 160000.0 0.33 614235.0 145000.0 0.31 0.4554 0.9997 1983099 ChemDiv1_028151 Clc1ccc(cc1)N2NC3(CCCCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P14 compound treatment 649042.0 191000.0 0.39 616889.0 148000.0 0.32 0.5053 0.9947 1983100 ChemDiv1_028152 CCC(C)(NC)c1nnnn1c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P15 compound treatment 636426.0 178000.0 0.37 631937.0 163000.0 0.35 0.5099 0.9998 1983101 ChemDiv1_028153 CN(O)C1(CCCCC1)c2nnnn2c3c(C)cccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P16 compound treatment 656974.0 199000.0 0.41 632811.0 164000.0 0.35 0.5413 0.9974 1983102 ChemDiv1_028154 CCOC(=O)C(NC(=O)c1ccccc1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P17 compound treatment 661948.0 204000.0 0.42 633517.0 165000.0 0.36 0.5496 0.9966 1515078 ChemDiv1_028155 O=C1N2CN(CN3C2C4N1CN(CN4C3=O)C5CCCCC5)C6CCCCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P18 compound treatment 639122.0 181000.0 0.37 629373.0 161000.0 0.35 0.5099 0.9993 1632305 ChemDiv1_028156 OC1=C(C(N(CCN2CCNCC2)C1=O)c3ccccc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P19 compound treatment 677783.0 220000.0 0.45 669493.0 201000.0 0.43 0.6278 0.9998 1983103 ChemDiv1_028157 CC(=O)C1=NN(C(N1C2CCCCC2)c3c[nH]c4ccccc34)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P20 compound treatment 605126.0 147000.0 0.3 613119.0 144000.0 0.31 0.4354 0.9999 1983104 ChemDiv1_028158 CCOC(=O)C(NC(=O)c1ccccc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P21 compound treatment 632599.0 175000.0 0.36 633252.0 164000.0 0.36 0.5063 1.0 1983105 ChemDiv1_028159 CCc1ccc(cc1)c2nnc3ccc4ccccc4n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P22 compound treatment 623276.0 165000.0 0.34 613205.0 144000.0 0.31 0.4621 0.999 1983106 ChemDiv1_028160 Cc1ccccc1C(O)(C(=O)NN(C(=O)c2ccc(Br)o2)c3ccccc3)c4ccccc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P23 mock treatment 603866.0 146000.0 0.3 623610.0 155000.0 0.33 0.4497 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.666 P24 mock treatment 345617.0 -112000.0 -0.23 324757.0 -144000.0 -0.31 -0.3847 -0.9894 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A01 compound treatment 610358.0 128000.0 0.26 557244.0 83500.0 0.18 0.3147 0.9828 1983107 ChemDiv1_028161 Cc1cccc(c1)C(O)(C(=O)NN(C(=O)c2ccc(Br)o2)c3ccccc3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A02 compound treatment 597984.0 116000.0 0.24 551593.0 77800.0 0.17 0.288 0.9854 1983108 ChemDiv1_028162 COc1c(Cl)cc(Cl)cc1C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A03 compound treatment 633118.0 151000.0 0.31 574137.0 100000.0 0.22 0.3738 0.9845 1983109 ChemDiv1_028163 Clc1ccc(CN2CCN(Cc3ccc(Cl)cc3)C2c4c(Cl)cccc4Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A04 compound treatment 622922.0 141000.0 0.29 584868.0 111000.0 0.24 0.3753 0.9956 1983110 ChemDiv1_028164 COC(=O)C1=NN(c2ccc(Br)cc2)C3(Nc4ccccc4S3)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A05 compound treatment 675799.0 193000.0 0.4 594189.0 120000.0 0.26 0.4667 0.9786 1659470 ChemDiv1_028165 Nc1cccc2C3CCCC3C(Nc12)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A06 compound treatment 656188.0 174000.0 0.36 616420.0 143000.0 0.31 0.4721 0.9972 1983111 ChemDiv1_028166 COC(=O)C(NC(=O)c1ccccc1Cl)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A07 compound treatment 648092.0 166000.0 0.34 615343.0 142000.0 0.31 0.4587 0.9985 1300481 ChemDiv1_028167 CC(C)C1N(CC2N1CCc3ccccc23)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A08 compound treatment 656406.0 174000.0 0.36 614748.0 141000.0 0.31 0.4699 0.9967 1166295 ChemDiv1_028168 Clc1ccc(CN2CCN(Cc3ccc(Cl)cc3)C2c4ccncc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A09 compound treatment 639961.0 158000.0 0.33 622725.0 149000.0 0.32 0.4581 1.0 1983112 ChemDiv1_028169 OCCOCCN1CCN(CC(=O)N2c3ccccc3Sc4ccc(Cl)cc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A10 compound treatment 660824.0 179000.0 0.37 628324.0 155000.0 0.33 0.4971 0.9988 1983113 ChemDiv1_028170 COc1ccc(cc1)C(O)(C(=O)NN(C(=O)c2ccccc2)c3ccccc3C)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A11 compound treatment 680396.0 198000.0 0.41 625599.0 152000.0 0.33 0.5215 0.9941 1983114 ChemDiv1_028171 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)CN4CCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A12 compound treatment 664345.0 182000.0 0.38 621062.0 147000.0 0.32 0.4912 0.9967 1983115 ChemDiv1_028172 CCOCCOC(=O)C1=C(C)NC(=O)CC1c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A13 compound treatment 656223.0 174000.0 0.36 618051.0 144000.0 0.31 0.4747 0.9976 1983116 ChemDiv1_028173 Cc1[nH]c2CC(C)(C)CC(=O)c2c1CC(Cl)(Cl)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A14 compound treatment 668630.0 186000.0 0.38 635114.0 161000.0 0.35 0.5189 0.9988 1247737 ChemDiv1_028174 Brc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A15 compound treatment 656831.0 175000.0 0.36 629853.0 156000.0 0.34 0.4936 0.9995 1983117 ChemDiv1_028175 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(F)c(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A16 compound treatment 658210.0 176000.0 0.36 571831.0 98100.0 0.21 0.4069 0.9673 1983118 ChemDiv1_028176 COC(=O)c1ccc(cc1)N2C(=O)CC(NCc3ccc(OC)c(OC)c3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A17 compound treatment 685617.0 203000.0 0.42 589495.0 116000.0 0.25 0.4739 0.9696 1270794 ChemDiv1_028177 Cc1c(CC(=O)O)c2C(=O)CC(C)(C)Cc2n1c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A18 compound treatment 648659.0 166000.0 0.34 631787.0 158000.0 0.34 0.4847 1.0 1542454 ChemDiv1_028178 COc1ccccc1C(O)(C(=O)NN(c2ccccc2)c3ccccc3)c4ccccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A19 compound treatment 676552.0 194000.0 0.4 606625.0 133000.0 0.29 0.4869 0.9867 1983119 ChemDiv1_028179 Cn1c(=O)n(Cc2cccc(c2)C(F)(F)F)c(=O)c3n(Cc4ccccc4)cnc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A20 compound treatment 667753.0 185000.0 0.38 583764.0 110000.0 0.24 0.439 0.9739 1731457 ChemDiv1_028180 Cn1c(=O)n(C)c2nc3n(Cc4ccccn4)c(cn3c2c1=O)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A21 compound treatment 639449.0 157000.0 0.32 592008.0 118000.0 0.26 0.4103 0.9931 1291026 ChemDiv1_028181 O=C(CSc1nnc2c3ccccc3[nH]c2n1)NCCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A22 compound treatment 638180.0 156000.0 0.32 580416.0 107000.0 0.23 0.3908 0.9867 1118473 ChemDiv1_028182 Fc1ccc(cc1)c2n[nH]cc2C3Nc4ccc5ccccc5c4C6=C3C(=O)CCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A23 mock treatment 608645.0 126000.0 0.26 560982.0 87200.0 0.19 0.3179 0.9874 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 A24 mock treatment 267362.0 -215000.0 -0.44 228282.0 -245000.0 -0.53 -0.6894 -0.996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B01 compound treatment 643190.0 161000.0 0.33 561449.0 87700.0 0.19 0.369 0.9648 1432021 ChemDiv1_028183 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5cccc6OCCOc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B02 compound treatment 673333.0 191000.0 0.39 613934.0 140000.0 0.3 0.4934 0.9916 1983120 ChemDiv1_028184 CC1=NN(C(=O)N)C2(O)CC3C(C12)C3(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B03 compound treatment 706518.0 224000.0 0.46 655830.0 182000.0 0.39 0.6059 0.9968 1130917 ChemDiv1_028185 Cc1ccc(cc1C)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B04 compound treatment 695906.0 214000.0 0.44 647015.0 173000.0 0.38 0.5769 0.9968 1561529 ChemDiv1_028186 Cc1cccc(C)c1NC(=O)C2(CCC(CC2)C(C)(C)C)NC(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B05 compound treatment 725179.0 243000.0 0.5 672977.0 199000.0 0.43 0.6594 0.9972 1983121 ChemDiv1_028187 Clc1cccc2nnc(c3ccc(Br)cc3)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B06 compound treatment 703735.0 221000.0 0.46 648903.0 175000.0 0.38 0.5913 0.9957 1983122 ChemDiv1_028188 COc1ccc(cc1)c2c[n+](CC(=O)OC3CC(C)CCC3C(C)C)c4CCCCCn24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B07 compound treatment 744922.0 263000.0 0.54 685763.0 212000.0 0.46 0.7078 0.9966 1648756 ChemDiv1_028189 CCOC(=O)c1nnn(c1CN2CC(C)OC(C)C2)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B08 compound treatment 711356.0 229000.0 0.47 692162.0 218000.0 0.47 0.6686 1.0 1983123 ChemDiv1_028190 CCOP(=O)(OCC)c1nc(oc1NCc2ccco2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B09 compound treatment 745456.0 263000.0 0.54 689359.0 216000.0 0.47 0.7141 0.9971 1983124 ChemDiv1_028191 CCOC(=O)C1C(C(C(=O)OCC)C(=O)C=C1C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B10 compound treatment 717234.0 235000.0 0.48 662726.0 189000.0 0.41 0.6321 0.9964 1159475 ChemDiv1_028192 Cc1ccc(NC(=O)C(NC(=O)c2ccc(C)cc2)C3(CC4CC5CC(C4)C3)C5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B11 compound treatment 718575.0 236000.0 0.49 700675.0 227000.0 0.49 0.6922 1.0 1330314 ChemDiv1_028193 CCN(CC)C(=O)N1CCN(CC1)c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B12 compound treatment 727135.0 245000.0 0.51 663058.0 189000.0 0.41 0.6471 0.9946 1935280 ChemDiv1_028194 Cc1nccn1S(=O)(=O)c2ccc(Cl)c(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B13 compound treatment 735525.0 253000.0 0.52 692461.0 219000.0 0.47 0.7043 0.9988 1983125 ChemDiv1_028195 CC(C)CCCC(C)C1CCC2C3CC=C4CC(CCC4(C)C3CCC12C)OC(=O)CC5CCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B14 compound treatment 736789.0 254000.0 0.53 701449.0 228000.0 0.49 0.7199 0.9995 1366043 ChemDiv1_028196 Clc1ccc(N2C(=O)C3C(C2=O)C4(C=O)c5ccccc5C3c6ccccc64)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B15 compound treatment 750687.0 268000.0 0.55 719824.0 246000.0 0.53 0.7683 0.9998 1983126 ChemDiv1_028197 Nc1ccc(cc1c2n[nH]c(=S)[nH]c2=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B16 compound treatment 731390.0 249000.0 0.51 640675.0 167000.0 0.36 0.619 0.9851 1983127 ChemDiv1_028198 C/C(=C/1\C2C3CCCCC3(NC1=O)Oc4ccccc24)/O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B17 compound treatment 767517.0 285000.0 0.59 666589.0 193000.0 0.42 0.7114 0.9858 1552290 ChemDiv1_028199 COc1ccc(Br)cc1C2N(CCN2c3cccc(C)c3)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B18 compound treatment 730067.0 248000.0 0.51 683205.0 209000.0 0.45 0.6822 0.9982 1983128 ChemDiv1_028200 CCCCSc1nnc2c3ccccc3n(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B19 compound treatment 757801.0 275000.0 0.57 725938.0 252000.0 0.55 0.7881 0.9998 1983129 ChemDiv1_028201 COc1ccc(/C=C/2\CCC/C(=C\c3ccc(cc3)N(C)C)/C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B20 compound treatment 713248.0 231000.0 0.48 669646.0 196000.0 0.42 0.6369 0.9983 1779361 ChemDiv1_028202 [O-][N+](=O)c1cc2OCOc2cc1C3N(Cc4ccccc4)CCN3Cc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B21 compound treatment 726790.0 244000.0 0.5 677802.0 204000.0 0.44 0.6691 0.9978 1983130 ChemDiv1_028203 CCCCCCCCn1c2cc(Cl)cc(Cl)c2c3c(Cl)cc(Cl)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B22 compound treatment 3947900.0 3470000.0 7.15 4201410.0 3730000.0 8.07 10.7637 0.9982 1983131 ChemDiv1_028204 CCOC(=O)c1cc2n(CC)c(/C=C/C=C3N(CC)c4cc(Cl)c(Cl)cc4N3CC)[n+](CC)c2cc1C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B23 mock treatment 849442.0 367000.0 0.76 772487.0 299000.0 0.65 0.9931 0.9969 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 B24 mock treatment 223434.0 -259000.0 -0.53 400185.0 -73600.0 -0.16 -0.4905 -0.8796 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C01 compound treatment 631870.0 150000.0 0.31 578266.0 105000.0 0.23 0.3783 0.9883 1948406 ChemDiv1_028205 CC1CCN(CC1)c2cc(N3CCN(CC3)C(=O)c4ccc(F)c(F)c4)c(cc2F)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C02 compound treatment 734870.0 253000.0 0.52 683916.0 210000.0 0.45 0.6903 0.9977 1983132 ChemDiv1_028206 CN(C)c1ccc(/C=C/C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C03 compound treatment 694079.0 212000.0 0.44 667521.0 194000.0 0.42 0.6057 0.9998 1983133 ChemDiv1_028207 Oc1c(Cl)cc(Cl)cc1C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C04 compound treatment 680238.0 198000.0 0.41 652854.0 179000.0 0.39 0.563 0.9997 1983134 ChemDiv1_028208 Clc1ccc(CN2CCN(Cc3ccc(Cl)cc3)C2/C=C/c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C05 compound treatment 711105.0 229000.0 0.47 698363.0 225000.0 0.49 0.6777 0.9999 1650022 ChemDiv1_028209 CC1(O)N(CCN2C(=O)OC3(CC(C)(C)NC(C)(C)C3)C2(C)O)C(=O)OC41CC(C)(C)NC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C06 compound treatment 693410.0 211000.0 0.44 657731.0 184000.0 0.4 0.5897 0.999 1983135 ChemDiv1_028210 Cc1cc(O)cc2OC3(CC(c4ccccc4)c12)CC(C)(C)N=C(N3)SCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C07 compound treatment 701082.0 219000.0 0.45 708182.0 234000.0 0.51 0.6781 0.9983 1371534 ChemDiv1_028211 Cc1ccc(cc1)S(=O)(=O)N2CC3N(CCc4ccccc34)C2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C08 compound treatment 702097.0 220000.0 0.45 711492.0 238000.0 0.51 0.6847 0.998 1983136 ChemDiv1_028212 CCOc1cccc(C2NC(CCSC)(C3C2C(=O)N(Cc4ccccc4)C3=O)C(=O)O)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C09 compound treatment 754855.0 273000.0 0.56 702445.0 229000.0 0.49 0.7478 0.998 1983137 ChemDiv1_028213 OCCN1CCN(CC(=O)N2c3ccccc3Sc4ccc(Cl)cc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C10 compound treatment 710879.0 229000.0 0.47 680219.0 206000.0 0.45 0.6496 0.9996 1329101 ChemDiv1_028214 Cc1ccc(Nc2nc3nonc3n4c(CC(=O)N)nnc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C11 compound treatment 739453.0 257000.0 0.53 708530.0 235000.0 0.51 0.7347 0.9998 1361117 ChemDiv1_028215 CC(C)C1=NCCc2cc(O)c(O)cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C12 compound treatment 685525.0 203000.0 0.42 647840.0 174000.0 0.38 0.5631 0.9986 1730790 ChemDiv1_028216 C(c1nnc2CCCCCn12)c3nnc4CCCCCn34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C13 compound treatment 747286.0 265000.0 0.55 687424.0 214000.0 0.46 0.7138 0.9965 1983138 ChemDiv1_028217 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(F)cc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C14 compound treatment 737785.0 255000.0 0.53 714336.0 241000.0 0.52 0.7411 1.0 1459263 ChemDiv1_028218 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2Cc5ccccn5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C15 compound treatment 730802.0 248000.0 0.51 724336.0 251000.0 0.54 0.7462 0.9996 1983139 ChemDiv1_028219 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(C)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C16 compound treatment 725320.0 243000.0 0.5 658075.0 184000.0 0.4 0.6368 0.9936 1983140 ChemDiv1_028220 COc1ccc(cc1)C(O)(C(=O)NN(C(=O)c2ccccc2)c3cccc(C)c3)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C17 compound treatment 748713.0 266000.0 0.55 666360.0 193000.0 0.42 0.6836 0.9907 1983141 ChemDiv1_028221 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3cc(ccc3Cl)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C18 compound treatment 726379.0 244000.0 0.5 707906.0 234000.0 0.51 0.7146 1.0 1983142 ChemDiv1_028222 Cc1cc(Br)ccc1N(NC(=O)C(O)(c2ccc(Cl)cc2)c3ccc(Cl)cc3)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C19 compound treatment 721325.0 239000.0 0.49 710732.0 237000.0 0.51 0.7116 0.9998 1983143 ChemDiv1_028223 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccc(C)cc4C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C20 compound treatment 710696.0 228000.0 0.47 697147.0 223000.0 0.48 0.6753 0.9999 1647018 ChemDiv1_028224 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc6OCCOc6c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C21 compound treatment 696689.0 214000.0 0.44 682615.0 209000.0 0.45 0.6326 0.9999 1983144 ChemDiv1_028225 CCOC(=O)C(NC(=O)c1cccc(Cl)c1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C22 compound treatment 695700.0 213000.0 0.44 681647.0 208000.0 0.45 0.6296 0.9999 1554600 ChemDiv1_028226 CCOc1cc(cc(Br)c1O)C2Nc3ccc4ccccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C23 mock treatment 794217.0 312000.0 0.64 716979.0 243000.0 0.53 0.8275 0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 C24 mock treatment 237602.0 -245000.0 -0.51 278536.0 -195000.0 -0.42 -0.656 -0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D01 compound treatment 640824.0 159000.0 0.33 583105.0 109000.0 0.24 0.3987 0.9874 1519447 ChemDiv1_028227 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(OC)c(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D02 compound treatment 664904.0 183000.0 0.38 621847.0 148000.0 0.32 0.4932 0.9968 1723682 ChemDiv1_028228 Clc1ccccc1C2=NCC(=O)Nc3ccc(Br)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D03 compound treatment 705459.0 223000.0 0.46 663752.0 190000.0 0.41 0.6165 0.9984 1176181 ChemDiv1_028229 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2Cc5ccccn5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D04 compound treatment 712332.0 230000.0 0.47 660662.0 187000.0 0.4 0.6218 0.9968 1983145 ChemDiv1_028230 OC(C(=O)NN(C(=O)c1cccs1)c2ccccc2)(c3ccc(Cl)cc3)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D05 compound treatment 757296.0 275000.0 0.57 701393.0 228000.0 0.49 0.7498 0.9975 1983146 ChemDiv1_028231 Fc1cccc(Cl)c1c2nnc3cccc(Cl)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D06 compound treatment 687106.0 205000.0 0.42 692684.0 219000.0 0.47 0.634 0.9984 1983147 ChemDiv1_028232 Cc1ccc(cc1)c2cnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D07 compound treatment 722843.0 241000.0 0.5 731295.0 258000.0 0.56 0.7452 0.9983 1983148 ChemDiv1_028233 Cn1c(=O)n(Cc2ccc(Cn3c(=O)n(C)c4ncn(Cc5ccccc5)c4c3=O)cc2)c(=O)c6n(Cc7ccccc7)cnc16 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D08 compound treatment 707181.0 225000.0 0.46 709494.0 236000.0 0.51 0.689 0.9989 1983149 ChemDiv1_028234 CC(=O)c1oc2ccc3c(C)cc(=O)oc3c2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D09 compound treatment 746911.0 265000.0 0.55 719169.0 245000.0 0.53 0.7618 0.9999 1480325 ChemDiv1_028235 C1CCN(C1)c2nc3nonc3n4nnnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D10 compound treatment 698383.0 216000.0 0.45 683931.0 210000.0 0.45 0.6371 1.0 1983150 ChemDiv1_028236 O=C(NC(=C(Oc1ccccc1)Oc2ccccc2)[P+](c3ccccc3)(c4ccccc4)c5ccccc5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D11 compound treatment 4.830176E7 4.78E7 98.71 3.8279308E7 3.78E7 81.83 127.6609 0.9957 1158532 ChemDiv1_028237 C=CCNc1ccc2c3nc4ccccc4n3c(=O)c5cccc1c52 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D12 compound treatment 721627.0 239000.0 0.49 668232.0 194000.0 0.42 0.647 0.9968 1374664 ChemDiv1_028238 CCOc1ccc(NC(=O)C(NC(=O)c2ccccc2)C3(CC4CC5CC(C4)C3)C5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D13 compound treatment 734652.0 252000.0 0.52 692829.0 219000.0 0.47 0.7036 0.9989 1983151 ChemDiv1_028239 CCCCOc1ccc(cc1)C(=O)Oc2ccc(cc2)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D14 compound treatment 752255.0 270000.0 0.56 730780.0 257000.0 0.56 0.7874 1.0 1915103 ChemDiv1_028240 Cc1ccc2c3c(C)c(cn3ccn12)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D15 compound treatment 779619.0 297000.0 0.61 768189.0 294000.0 0.64 0.8846 0.9998 1661460 ChemDiv1_028241 O=c1nc2[nH]c3ccccc3nc2c(=O)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D16 compound treatment 711943.0 230000.0 0.47 676505.0 203000.0 0.44 0.6455 0.9993 1421536 ChemDiv1_028242 O=S(=O)(c1nc(Cc2ccccc2)oc1NCc3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D17 compound treatment 768556.0 286000.0 0.59 685486.0 212000.0 0.46 0.7419 0.9921 1413912 ChemDiv1_028243 CN1C2CCC1C=C(C2)N(CCc3ccccc3)C(=O)c4cc(C)cc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D18 compound treatment 697792.0 215000.0 0.44 688764.0 215000.0 0.47 0.6436 0.9997 1187759 ChemDiv1_028244 O=C(N1c2ccccc2Sc3ccccc13)c4ccc(cc4)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D19 compound treatment 707875.0 226000.0 0.47 709661.0 236000.0 0.51 0.6903 0.9989 1983152 ChemDiv1_028245 [O-][N+](=O)c1cc(C(=O)N2CC(=O)Nc3ccccc23)c(Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D20 compound treatment 768005.0 286000.0 0.59 787676.0 314000.0 0.68 0.8975 0.9975 1463148 ChemDiv1_028246 Brc1ccc(cc1)c2cn3c(C(=S)NCC=C)c(c4CCCCn2c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D21 compound treatment 738435.0 256000.0 0.53 732761.0 259000.0 0.56 0.7702 0.9996 1540991 ChemDiv1_028247 COc1cccc(Nc2ccc3noc4-c5ccccc5C(=O)c2c43)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D22 compound treatment 787927.0 306000.0 0.63 787887.0 314000.0 0.68 0.9269 0.9993 1983153 ChemDiv1_028248 CCCCCCC(CCN1/C(=C/C=C/c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)/N(CC)c4cc(Cl)c(Cl)cc14)S(=O)(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D23 mock treatment 769574.0 287000.0 0.59 665697.0 192000.0 0.42 0.7131 0.9849 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 D24 mock treatment 239947.0 -242000.0 -0.5 223957.0 -250000.0 -0.54 -0.7361 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E01 compound treatment 647110.0 165000.0 0.34 579722.0 106000.0 0.23 0.4027 0.9816 1732494 ChemDiv1_028249 CC1(C)CC(CC(C)(C)N1)NC(=O)CCC(=O)N2C(C)(C)CC(N)CC2(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E02 compound treatment 679133.0 197000.0 0.41 602873.0 129000.0 0.28 0.4849 0.9833 1171602 ChemDiv1_028250 CSc1ccc(Cl)c(c1)C(=O)Nc2ccc3CCc4ccccc4N(C(=O)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E03 compound treatment 694484.0 212000.0 0.44 658093.0 184000.0 0.4 0.5918 0.9989 1983154 ChemDiv1_028251 Clc1ccc(CN2CCN(Cc3ccc(Cl)cc3)C2c4cccc(Br)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E04 compound treatment 692142.0 210000.0 0.43 666732.0 193000.0 0.42 0.6016 0.9998 1983155 ChemDiv1_028252 OC(C(=O)NNc1ccc(Br)cc1Br)(c2ccc(Cl)cc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E05 compound treatment 765064.0 283000.0 0.58 666631.0 193000.0 0.42 0.7079 0.9865 1360757 ChemDiv1_028253 Cn1c(=O)n(C)c2nc3[nH]c4ccccc4c3nc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E06 compound treatment 693949.0 212000.0 0.44 661736.0 188000.0 0.41 0.5966 0.9994 1983156 ChemDiv1_028254 COc1cc(/C=N/n2cnnc2n3nc(C)cc3C)cc([N+](=O)[O-])c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E07 compound treatment 725141.0 243000.0 0.5 693575.0 220000.0 0.48 0.6909 0.9997 1983157 ChemDiv1_028255 CC(=O)Nc1ccc(cc1)C2Nc3ccccc3C(O2)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E08 compound treatment 724471.0 242000.0 0.5 710298.0 237000.0 0.51 0.7155 0.9999 1657249 ChemDiv1_028256 Cc1ccc(cc1C)N2NC3(CCCCC3)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E09 compound treatment 751066.0 269000.0 0.55 703392.0 230000.0 0.5 0.7437 0.9985 1602539 ChemDiv1_028257 COc1ccc(cc1)C2N(CC3N2CCc4ccccc34)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E10 compound treatment 717790.0 235000.0 0.49 694014.0 220000.0 0.48 0.6808 1.0 1400140 ChemDiv1_028258 CCC(=O)Nc1nc2CCCCc2c3c4ccccc4oc(=O)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E11 compound treatment 748887.0 267000.0 0.55 725103.0 251000.0 0.54 0.7738 1.0 1983158 ChemDiv1_028259 Clc1ccc2Sc3ccccc3N(C(=O)CNCc4cccnc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E12 compound treatment 727359.0 245000.0 0.51 645224.0 171000.0 0.37 0.6201 0.9884 1983159 ChemDiv1_028260 CCOC(=O)C1(C)CC(=O)C(=O)N1c2cccc(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E13 compound treatment 736727.0 254000.0 0.53 673892.0 200000.0 0.43 0.6777 0.9954 1983160 ChemDiv1_028261 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3cc(ccc3C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E14 compound treatment 743287.0 261000.0 0.54 703540.0 230000.0 0.5 0.7326 0.9992 1459142 ChemDiv1_028262 Cn1c(=O)n(C)c2nc3n(Cc4ccccc4)c(cn3c2c1=O)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E15 compound treatment 741088.0 259000.0 0.53 685563.0 212000.0 0.46 0.7019 0.9971 1983161 ChemDiv1_028263 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E16 compound treatment 731151.0 249000.0 0.51 708863.0 235000.0 0.51 0.723 1.0 1983162 ChemDiv1_028264 COc1ccc(cc1)C(C(=O)NN(C(=O)C)c2ccccc2)(c3ccc(F)cc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E17 compound treatment 760897.0 279000.0 0.58 676092.0 202000.0 0.44 0.7163 0.991 1983163 ChemDiv1_028265 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CCCc2n1c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E18 compound treatment 727699.0 245000.0 0.51 671637.0 198000.0 0.43 0.661 0.9965 1983164 ChemDiv1_028266 COc1ccccc1C(O)(C(=O)NN(C(=O)c2ccccc2)c3ccccc3Cl)c4ccccc4OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E19 compound treatment 717688.0 235000.0 0.49 696468.0 223000.0 0.48 0.6844 1.0 1983165 ChemDiv1_028267 Cn1c(c(C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5)c6ccccc16)c7ccccc7 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E20 compound treatment 710863.0 229000.0 0.47 695123.0 221000.0 0.48 0.6724 1.0 1230631 ChemDiv1_028268 COc1ccc(cc1OC)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E21 compound treatment 716356.0 234000.0 0.48 696026.0 222000.0 0.48 0.6818 1.0 1983166 ChemDiv1_028269 COC(=O)C(NC(=O)c1ccc(Cl)cc1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E22 compound treatment 672755.0 190000.0 0.39 665725.0 192000.0 0.42 0.5718 0.9996 1983167 ChemDiv1_028270 Fc1ccccc1COc2ccc(cc2)C3Nc4ccc5ccccc5c4C6=C3C(=O)CCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E23 mock treatment 689758.0 207000.0 0.43 660147.0 186000.0 0.4 0.5881 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 E24 mock treatment 202920.0 -279000.0 -0.58 240136.0 -234000.0 -0.51 -0.7654 -0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F01 compound treatment 673182.0 191000.0 0.39 595607.0 122000.0 0.26 0.4651 0.981 1983168 ChemDiv1_028271 OCCOCCN1CCN(CC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F02 compound treatment 666921.0 185000.0 0.38 625328.0 152000.0 0.33 0.5014 0.9972 1604042 ChemDiv1_028272 CC(C)(C)C(=O)OCCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F03 compound treatment 720173.0 238000.0 0.49 685856.0 212000.0 0.46 0.6718 0.9994 1735945 ChemDiv1_028273 Cn1c(=O)n(C)c2nc3n(Cc4ccccc4)c(cn3c2c1=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F04 compound treatment 519653.0 37300.0 0.08 474492.0 742.0 0.0 0.0556 0.7217 1402195 ChemDiv1_028274 CCCOc1ccc-2c(c1)C(=O)c3cc(O)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F05 compound treatment 702138.0 220000.0 0.45 684863.0 211000.0 0.46 0.644 1.0 1983169 ChemDiv1_028275 [O-][N+](=O)c1ccc(/C=C/CSc2nnc(c3ccco3)n2c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F06 compound treatment 721024.0 239000.0 0.49 671712.0 198000.0 0.43 0.6514 0.9976 1509102 ChemDiv1_028276 CCOC(=O)C1C(C(C(=O)OCC)S(=O)(=O)CS1(=O)=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F07 compound treatment 766602.0 284000.0 0.59 681040.0 207000.0 0.45 0.7322 0.9912 1552257 ChemDiv1_028277 COc1ccc(cc1OC)c2nn(CN3CCCCC3)c(=S)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F08 compound treatment 752149.0 270000.0 0.56 718612.0 245000.0 0.53 0.7686 0.9997 1547314 ChemDiv1_028278 COc1ccc(Nc2c3-c4ccccc4C(=O)c5cccc(n(C)c2=O)c53)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F09 compound treatment 480827.0 -1490.0 0.0 460271.0 -13500.0 -0.03 -0.0228 -0.7775 1983170 ChemDiv1_028279 FC(F)(F)c1nc2cccc3cccc([nH]1)c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F10 compound treatment 647393.0 165000.0 0.34 623015.0 149000.0 0.32 0.4694 0.9996 1983171 ChemDiv1_028280 COC(=O)C1C(C(C(=O)OC)S(=O)(=O)C(=NNc2ccc(OC)cc2[N+](=O)[O-])S1(=O)=O)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F11 compound treatment 719325.0 237000.0 0.49 746823.0 273000.0 0.59 0.7639 0.9956 1983172 ChemDiv1_028281 COC(C)C(=O)C1(CC2CC3CC(C2)C1)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F12 compound treatment 736170.0 254000.0 0.52 712332.0 239000.0 0.52 0.7357 1.0 1983173 ChemDiv1_028282 Cc1cn([C@@H]2O[C@H](CO)[C@H](O)C2O)c(=O)[nH]c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F13 compound treatment 738661.0 256000.0 0.53 716282.0 243000.0 0.52 0.7454 1.0 1983174 ChemDiv1_028283 CCCCOc1ccc(cc1)C(=O)Oc2ccc(C#N)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F14 compound treatment 728738.0 246000.0 0.51 712585.0 239000.0 0.52 0.7252 1.0 1983175 ChemDiv1_028284 CCOC(=O)C1=NN(c2ccccc2)C3(S1)N(N=C(c4ccc(Cl)cc4)c5ccccc53)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F15 compound treatment 735738.0 253000.0 0.52 739992.0 266000.0 0.58 0.7774 0.9988 1983176 ChemDiv1_028285 CC(=O)Nc1ccc2OCCOCCOc3cc(NC(=O)C)ccc3OCCOCCOc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F16 compound treatment 734842.0 253000.0 0.52 728386.0 255000.0 0.55 0.7583 0.9996 1138215 ChemDiv1_028286 CN1CCN(CC(O)Cn2c3ccccc3c4ccccc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F17 compound treatment 764102.0 282000.0 0.58 693819.0 220000.0 0.48 0.7481 0.9951 1584429 ChemDiv1_028287 CN1C2CCC1C=C(C2)N(C(=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F18 compound treatment 718345.0 236000.0 0.49 684499.0 211000.0 0.46 0.6671 0.9995 1983177 ChemDiv1_028288 CC(=O)c1cccc(c1)N2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F19 compound treatment 740185.0 258000.0 0.53 720452.0 247000.0 0.53 0.754 1.0 1983178 ChemDiv1_028289 [O-][N+](=O)c1cc(ccc1N2CCOCC2)C(=O)N3CC(=O)Nc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F20 compound treatment 725538.0 243000.0 0.5 689941.0 216000.0 0.47 0.6859 0.9994 1983179 ChemDiv1_028290 CN1C2NNC(=N)NC2N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F21 compound treatment 740628.0 258000.0 0.53 744938.0 271000.0 0.59 0.7921 0.9989 1184164 ChemDiv1_028291 CCOc1ccc(Nc2ccc3noc4-c5ccccc5C(=O)c2c43)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F22 compound treatment 378404.0 -104000.0 -0.21 367608.0 -106000.0 -0.23 -0.3141 -0.9994 1983180 ChemDiv1_028292 CCN1C=C/C(=C/C=C\c2ccc3ccccc3[n+]2CC)/c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F23 mock treatment 693057.0 211000.0 0.44 676263.0 203000.0 0.44 0.6175 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 F24 mock treatment 216418.0 -266000.0 -0.55 217067.0 -257000.0 -0.56 -0.781 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G01 compound treatment 646044.0 164000.0 0.34 575260.0 102000.0 0.22 0.3943 0.9782 1983181 ChemDiv1_028293 CCOC(=O)C(NC(=O)c1ccccc1F)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G02 compound treatment 684309.0 202000.0 0.42 662589.0 189000.0 0.41 0.5838 1.0 1478305 ChemDiv1_028294 CCc1ccc(OCC(=O)Nc2ccc3CCc4ccccc4N(C(=O)C)c3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G03 compound treatment 710627.0 228000.0 0.47 669382.0 196000.0 0.42 0.6327 0.9986 1983182 ChemDiv1_028295 C(N1CCN(Cc2ccccc2)C1/C=C/c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G04 compound treatment 699613.0 217000.0 0.45 651105.0 177000.0 0.38 0.5886 0.997 1983183 ChemDiv1_028296 COC(=O)C(NC(=O)c1ccc(C)cc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G05 compound treatment 714993.0 233000.0 0.48 669707.0 196000.0 0.42 0.6395 0.9981 1092518 ChemDiv1_028297 OCCN1CCN(CC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G06 compound treatment 694873.0 213000.0 0.44 658637.0 185000.0 0.4 0.5932 0.9989 1983184 ChemDiv1_028298 COc1cc(/C=N/n2cnnc2n3nc(C)cc3C)cc(Br)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G07 compound treatment 736311.0 254000.0 0.52 681752.0 208000.0 0.45 0.6891 0.9971 1983185 ChemDiv1_028299 COCc1cc(C)c2c3noc(c4ccccc4)c3sc2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G08 compound treatment 718955.0 237000.0 0.49 683147.0 209000.0 0.45 0.6659 0.9993 1983186 ChemDiv1_028300 COC(=O)C(NC(=O)C)(Nc1ccccn1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G09 compound treatment 761443.0 279000.0 0.58 678564.0 205000.0 0.44 0.7209 0.9916 1405212 ChemDiv1_028301 COc1ccc(cc1)C2N(CC3N2CCc4ccccc34)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G10 compound treatment 732293.0 250000.0 0.52 667798.0 194000.0 0.42 0.6619 0.9948 1518021 ChemDiv1_028302 CCc1ccc(cc1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G11 compound treatment 741846.0 260000.0 0.54 719175.0 245000.0 0.53 0.7544 1.0 1983187 ChemDiv1_028303 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)CCCCCN4C(=O)c5ccccc5C4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G12 compound treatment 723358.0 241000.0 0.5 697202.0 223000.0 0.48 0.6938 0.9999 1446231 ChemDiv1_028304 Cc1ccc(cc1)N2C(C3=C(NCCN=C3c4ccc(Cl)cc4)C2=O)c5ccc(O)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G13 compound treatment 726396.0 244000.0 0.5 712869.0 239000.0 0.52 0.7222 0.9999 1983188 ChemDiv1_028305 CCOC(=O)Cn1c(C)c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G14 compound treatment 729879.0 248000.0 0.51 718474.0 245000.0 0.53 0.7359 0.9998 1159619 ChemDiv1_028306 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccc(Br)cc4)c5cccc6ccccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G15 compound treatment 750465.0 268000.0 0.55 723770.0 250000.0 0.54 0.774 0.9999 1983189 ChemDiv1_028307 CN(C)n1c(C)c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G16 compound treatment 741044.0 259000.0 0.53 721643.0 248000.0 0.54 0.757 1.0 1983190 ChemDiv1_028308 COc1ccc(cc1)N(NC(=O)C(c2ccc(C)cc2)(c3ccc(C)cc3)c4ccc(OC)cc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G17 compound treatment 780825.0 299000.0 0.62 686739.0 213000.0 0.46 0.7617 0.9898 1983191 ChemDiv1_028309 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G18 compound treatment 734556.0 252000.0 0.52 634600.0 161000.0 0.35 0.6144 0.9808 1983192 ChemDiv1_028310 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CNCc4cccnc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G19 compound treatment 726215.0 244000.0 0.5 729918.0 256000.0 0.55 0.7481 0.9988 1315305 ChemDiv1_028311 Cn1c(=O)n(C)c2nc(O)n(Cc3ccc(Cl)cc3Cl)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G20 compound treatment 718414.0 236000.0 0.49 698322.0 225000.0 0.49 0.6883 1.0 1983193 ChemDiv1_028312 CCCCCCCCOc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G21 compound treatment 765586.0 283000.0 0.58 717661.0 244000.0 0.53 0.7868 0.9987 1983194 ChemDiv1_028313 CCOC(=O)C(NC(=O)c1cccc(Cl)c1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G22 compound treatment 696629.0 214000.0 0.44 674391.0 201000.0 0.43 0.6199 1.0 1983195 ChemDiv1_028314 COC(=O)C(NC(=O)c1cccc(Cl)c1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G23 mock treatment 680785.0 198000.0 0.41 669057.0 195000.0 0.42 0.5886 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 G24 mock treatment 215067.0 -267000.0 -0.55 205538.0 -268000.0 -0.58 -0.8006 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H01 compound treatment 615568.0 133000.0 0.28 582570.0 109000.0 0.24 0.361 0.997 1983196 ChemDiv1_028315 Clc1cccc(Cl)c1c2nnc3cccc(Cl)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H02 compound treatment 668107.0 186000.0 0.38 611097.0 137000.0 0.3 0.4814 0.9921 1005423 ChemDiv1_028316 O=C1OC(c2ccccc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H03 compound treatment 1250073.0 768000.0 1.58 1081030.0 607000.0 1.31 2.0501 0.9957 1510360 ChemDiv1_028317 C1CCc2nn3cc(nc3nc2C1)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H04 compound treatment 719754.0 237000.0 0.49 632914.0 159000.0 0.34 0.5902 0.9851 1983197 ChemDiv1_028318 COc1ccc(cc1)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H05 compound treatment 672282.0 190000.0 0.39 691661.0 218000.0 0.47 0.6108 0.9958 1983198 ChemDiv1_028319 Clc1cccc2nnc(c3cccc(I)c3)n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H06 compound treatment 677146.0 195000.0 0.4 665830.0 192000.0 0.42 0.5784 0.9999 1983199 ChemDiv1_028320 COc1ccc(cc1)c2c[n+](CC(=O)c3ccccc3)c4CCCCCn24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H07 compound treatment 716941.0 235000.0 0.48 697092.0 223000.0 0.48 0.6843 1.0 1432408 ChemDiv1_028321 Clc1ccc(cc1)c2nn(CN3CCC4(CC3)OCCO4)c(=S)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H08 compound treatment 699664.0 217000.0 0.45 667798.0 194000.0 0.42 0.6142 0.9995 1486214 ChemDiv1_028322 CCSc1nnc2c3cccc(C)c3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H09 compound treatment 722313.0 240000.0 0.5 704085.0 230000.0 0.5 0.7028 1.0 1983200 ChemDiv1_028323 CCCCN1CCCCC1C(=O)Nc2c(C)ccc(c2C)S(=O)(=O)N3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H10 compound treatment 705908.0 224000.0 0.46 678860.0 205000.0 0.44 0.6403 0.9998 1460868 ChemDiv1_028324 CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H11 compound treatment 714293.0 232000.0 0.48 726626.0 253000.0 0.55 0.7256 0.9978 1983201 ChemDiv1_028325 Oc1c(Cl)cc(Cl)cc1C(=O)Nc2ccc(Oc3ccc4ccccc4c3Br)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H12 compound treatment 686900.0 205000.0 0.42 686007.0 212000.0 0.46 0.6235 0.9991 1248815 ChemDiv1_028326 Cc1cn(C2CC(OC(=O)c3ccccc3)C(COC(=O)c4ccccc4)O2)c(=O)[nH]c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H13 compound treatment 1401186.0 919000.0 1.9 1045430.0 572000.0 1.24 2.2162 0.9786 1146340 ChemDiv1_028327 O=C1c2ccccc2-c3onc4ccc(Oc5ccccc5)c1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H14 compound treatment 688537.0 206000.0 0.43 700315.0 227000.0 0.49 0.6478 0.9975 1646988 ChemDiv1_028328 COC(=O)C1C2CC(C)(NC1=O)Oc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H15 compound treatment 703264.0 221000.0 0.46 734640.0 261000.0 0.56 0.7218 0.9944 1983202 ChemDiv1_028329 COC(=O)CCC/C=C\1/SCC(NC(=O)c2ccccc2)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H16 compound treatment 738717.0 256000.0 0.53 711938.0 238000.0 0.52 0.7388 0.9999 1381229 ChemDiv1_028330 CCCS(=O)(=O)c1c(C(=O)c2ccccc2)n3ccc4ccccc4c3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H17 compound treatment 728782.0 246000.0 0.51 687690.0 214000.0 0.46 0.6872 0.9989 1119678 ChemDiv1_028331 Cc1ccc2NC(=O)CN=C(c3ccccc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H18 compound treatment 685959.0 204000.0 0.42 677274.0 204000.0 0.44 0.6087 0.9997 1196166 ChemDiv1_028332 CC(C)C(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H19 compound treatment 715040.0 233000.0 0.48 733685.0 260000.0 0.56 0.7375 0.9969 1983203 ChemDiv1_028333 [O-][N+](=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc(cc3)[N+](=O)[O-])c4ccc(Oc5ccc(cc5)c6[nH]c(nc6c7ccc(cc7)[N+](=O)[O-])c8ccc(cc8)[N+](=O)[O-])cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H20 compound treatment 697439.0 215000.0 0.44 661273.0 188000.0 0.41 0.601 0.999 1406845 ChemDiv1_028334 Cc1nn2cc(nc2[nH]c1=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H21 compound treatment 715788.0 233000.0 0.48 693112.0 219000.0 0.47 0.6765 1.0 1983204 ChemDiv1_028335 Brc1ccc(cc1)c2nnc3CCCCCn23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H22 compound treatment 1.1833898E7 1.14E7 23.43 1.1564467E7 1.11E7 24.0 33.5435 0.9999 1983205 ChemDiv1_028336 CN1/C(=C/C=C/c2n(CCCOC(=O)C)c3cc(Cl)c(Cl)cc3[n+]2C)/N(CCCOC(=O)C)c4cc(Cl)c(Cl)cc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H23 mock treatment 716345.0 234000.0 0.48 666673.0 193000.0 0.42 0.6369 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 H24 mock treatment 233214.0 -249000.0 -0.51 189066.0 -285000.0 -0.62 -0.7993 -0.996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I01 compound treatment 648131.0 166000.0 0.34 575102.0 101000.0 0.22 0.3971 0.9769 1508851 ChemDiv1_028337 CCC(=O)Nc1nc2CCC(Cc2c3c4ccccc4oc(=O)c13)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I02 compound treatment 682027.0 200000.0 0.41 610567.0 137000.0 0.3 0.5009 0.9868 1341001 ChemDiv1_028338 Cc1ccsc1C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I03 compound treatment 724215.0 242000.0 0.5 647154.0 173000.0 0.38 0.6185 0.9901 1560530 ChemDiv1_028339 Fc1ccc(cc1)C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I04 compound treatment 736108.0 254000.0 0.52 661399.0 188000.0 0.41 0.6576 0.9921 1983206 ChemDiv1_028340 COC(=O)C(NC(=O)c1ccccc1Cl)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I05 compound treatment 712606.0 230000.0 0.48 655964.0 182000.0 0.39 0.615 0.9957 1667999 ChemDiv1_028341 Cc1cc(=O)oc2c3cc(Nc4ccccc4)oc3ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I06 compound treatment 714833.0 233000.0 0.48 683655.0 210000.0 0.45 0.6606 0.9996 1247552 ChemDiv1_028342 Cc1ccccc1NC(=O)c2c(NC(=O)c3ccc(F)cc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I07 compound treatment 736592.0 254000.0 0.52 687277.0 214000.0 0.46 0.6979 0.998 1983207 ChemDiv1_028343 Cc1cc(C)c2c3noc(c4ccccc4)c3sc2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I08 compound treatment 728122.0 246000.0 0.51 674656.0 201000.0 0.43 0.6663 0.997 1983208 ChemDiv1_028344 COC(=O)C(NC(=O)C)(Nc1ccc(C)cn1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I09 compound treatment 744484.0 262000.0 0.54 690019.0 216000.0 0.47 0.7137 0.9974 1587072 ChemDiv1_028345 O=S(=O)(N1CC2N(CCc3ccccc23)C1c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I10 compound treatment 726604.0 244000.0 0.5 682210.0 208000.0 0.45 0.6756 0.9985 1677143 ChemDiv1_028346 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4cccnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I11 compound treatment 742457.0 260000.0 0.54 637345.0 164000.0 0.35 0.6301 0.9796 1377803 ChemDiv1_028347 CC1(C)CC(CC(C)(C)N1)NCc2ccccc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I12 compound treatment 741544.0 259000.0 0.54 608231.0 134000.0 0.29 0.5842 0.959 1700871 ChemDiv1_028348 OC1=C(C(=O)c2cccc(Br)c2)C3(OC1=O)C(=O)c4ccccc4C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I13 compound treatment 712332.0 230000.0 0.47 671753.0 198000.0 0.43 0.6388 0.9987 1983209 ChemDiv1_028349 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CCCc2n1c3ccccc3[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I14 compound treatment 786239.0 304000.0 0.63 757052.0 283000.0 0.61 0.8772 0.9999 1409040 ChemDiv1_028350 COc1ccc(cc1)c2cn3nc(C)c(C)nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I15 compound treatment 734277.0 252000.0 0.52 681887.0 208000.0 0.45 0.6863 0.9974 1983210 ChemDiv1_028351 CCCCCn1c(C)c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I16 compound treatment 733569.0 251000.0 0.52 701383.0 228000.0 0.49 0.7151 0.9997 1983211 ChemDiv1_028352 COc1ccc(cc1)C(C(=O)NN(C(=O)c2ccccc2OC)c3ccccc3)(c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I17 compound treatment 731589.0 249000.0 0.51 669605.0 196000.0 0.42 0.6636 0.9954 1983212 ChemDiv1_028353 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CCCc2n1c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I18 compound treatment 721773.0 239000.0 0.49 686412.0 213000.0 0.46 0.675 0.9994 1704424 ChemDiv1_028354 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccc(OCc5ccccc5F)cc4)ccc6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I19 compound treatment 739153.0 257000.0 0.53 712985.0 239000.0 0.52 0.741 0.9999 1553137 ChemDiv1_028355 CCOC(=O)Cc1nnc2c(Nc3ccc(Cl)cc3)nc4nonc4n12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I20 compound treatment 734875.0 253000.0 0.52 673888.0 200000.0 0.43 0.675 0.9958 1983213 ChemDiv1_028356 CC1(C)OC(=O)N(C2CC2)C1(C)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I21 compound treatment 787933.0 306000.0 0.63 707403.0 234000.0 0.51 0.8037 0.994 1983214 ChemDiv1_028357 COC(=O)C(NC(=O)c1ccc(Cl)cc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I22 compound treatment 698211.0 216000.0 0.45 662871.0 189000.0 0.41 0.6046 0.9991 1195303 ChemDiv1_028358 CCOc1cc(ccc1OC)C2N(CC3N2CCc4ccccc34)S(=O)(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I23 mock treatment 731217.0 249000.0 0.51 670763.0 197000.0 0.43 0.6648 0.9957 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 I24 mock treatment 224418.0 -258000.0 -0.53 205391.0 -268000.0 -0.58 -0.7872 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J01 compound treatment 632948.0 151000.0 0.31 598904.0 125000.0 0.27 0.4114 0.9976 1948243 ChemDiv1_028359 C(Sc1nnc(c2ccco2)n1c3ccccc3)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J02 compound treatment 642749.0 160000.0 0.33 631213.0 157000.0 0.34 0.4752 0.9999 1240065 ChemDiv1_028360 CN(C(=O)c1ccccc1F)C2(CCC(CC2)C(C)(C)C)C(=O)Nc3c(C)cccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J03 compound treatment 705572.0 223000.0 0.46 681723.0 208000.0 0.45 0.6442 0.9999 1983215 ChemDiv1_028361 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4cc(Br)cc(Cl)c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J04 compound treatment 672063.0 190000.0 0.39 632301.0 159000.0 0.34 0.5196 0.9978 1559 ChemDiv1_028362 Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J05 compound treatment 718457.0 236000.0 0.49 683277.0 210000.0 0.45 0.6654 0.9993 1983216 ChemDiv1_028363 FC(F)(F)c1ccc(cc1)c2nnc3cccc(Cl)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J06 compound treatment 702731.0 220000.0 0.45 704141.0 230000.0 0.5 0.6743 0.999 1983217 ChemDiv1_028364 CCCCCc1ccc(cc1)c2ccc(cc2)C(=O)OC34CCC5(CCC)CC4CCC5C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J07 compound treatment 726561.0 244000.0 0.5 723607.0 250000.0 0.54 0.7389 0.9994 1418249 ChemDiv1_028365 COc1cccc(c1)c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J08 compound treatment 819661.0 337000.0 0.7 748823.0 275000.0 0.6 0.9134 0.997 1615257 ChemDiv1_028366 COc1ccc(cc1)C2C(N3C(C=Cc4ccccc34)C2(C#N)C#N)C(=O)c5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J09 compound treatment 728128.0 246000.0 0.51 673384.0 200000.0 0.43 0.6643 0.9968 1983218 ChemDiv1_028367 O/N=C/1\C2CCN(CC2)\C1=C\c3cccc(O)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J10 compound treatment 705794.0 223000.0 0.46 666935.0 193000.0 0.42 0.6219 0.9988 1983219 ChemDiv1_028368 Cc1ccc(cc1)C(=O)N/C(=C\c2cn(nc2c3ccc(F)cc3)c4ccccc4)/C(=O)NCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J11 compound treatment 708754.0 226000.0 0.47 669712.0 196000.0 0.42 0.6304 0.9988 1247964 ChemDiv1_028369 CC(C)(C)c1cc(CN2CCCCCC2)cc(c1O)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J12 compound treatment 697364.0 215000.0 0.44 695055.0 221000.0 0.48 0.6526 0.9993 1983220 ChemDiv1_028370 CCOC(=O)/C=C/1\NC(C)(C)Cc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J13 compound treatment 715098.0 233000.0 0.48 705155.0 231000.0 0.5 0.6939 0.9998 1632208 ChemDiv1_028371 CCN(CC)CCOc1cc2C(=O)c3cc(OCCN(CC)CC)c(Cl)cc3-c2cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J14 compound treatment 728029.0 246000.0 0.51 711025.0 237000.0 0.51 0.7218 1.0 1983221 ChemDiv1_028372 CN1CCC2(NC(=O)/C(=C(/C)\O)/C3C2C1)Oc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J15 compound treatment 721541.0 239000.0 0.49 726511.0 253000.0 0.55 0.736 0.9987 1983222 ChemDiv1_028373 COC(=O)CCCCC1SCC(NC(=O)c2ccccc2)C1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J16 compound treatment 711938.0 230000.0 0.47 707436.0 234000.0 0.51 0.6928 0.9995 1983223 ChemDiv1_028374 CCCS(=O)(=O)c1c(C(=O)c2ccc(cc2)[N+](=O)[O-])n3ccc(cc3c1S(=O)(=O)CCC)c4ccncc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J17 compound treatment 707102.0 225000.0 0.46 684445.0 211000.0 0.46 0.6506 1.0 1602871 ChemDiv1_028375 CN(C)C1(CCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J18 compound treatment 694373.0 212000.0 0.44 720555.0 247000.0 0.53 0.6873 0.9951 1426761 ChemDiv1_028376 Cc1ccc2n(CC(O)CN3C(=O)CCC3=O)c(c(c4ccccc4)c2c1)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J19 compound treatment 716414.0 234000.0 0.48 687004.0 213000.0 0.46 0.6681 0.9997 1597278 ChemDiv1_028377 CCC(=O)NCC1(CC2CC3C1)CC(C2)(C3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J20 compound treatment 734210.0 252000.0 0.52 700040.0 226000.0 0.49 0.714 0.9996 1983224 ChemDiv1_028378 CN(C)c1oc(nc1P(=O)(c2ccccc2)c3ccccc3)c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J21 compound treatment 748782.0 266000.0 0.55 716516.0 243000.0 0.53 0.7605 0.9997 1348727 ChemDiv1_028379 CN1C(=O)CC(=Nc2ccc(C)cc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J22 compound treatment 752132.0 270000.0 0.56 736440.0 263000.0 0.57 0.7959 0.9999 1983225 ChemDiv1_028380 C[N+]1=C(/C(=C/C=C/C=C/c2c(c3ccccc3)n(C)c4ccccc24)/c5ccccc15)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J23 mock treatment 717538.0 235000.0 0.49 689240.0 215000.0 0.47 0.6731 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 J24 mock treatment 212983.0 -269000.0 -0.56 228910.0 -245000.0 -0.53 -0.7679 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K01 compound treatment 657784.0 175000.0 0.36 579634.0 106000.0 0.23 0.4182 0.9756 1703872 ChemDiv1_028381 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K02 compound treatment 679979.0 198000.0 0.41 610262.0 137000.0 0.3 0.4974 0.9874 1139057 ChemDiv1_028382 CSc1ccccc1C(=O)Nc2ccc3CCc4ccccc4N(C(=O)C)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K03 compound treatment 724770.0 242000.0 0.5 667853.0 194000.0 0.42 0.651 0.9962 1983226 ChemDiv1_028383 CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3)c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K04 compound treatment 696614.0 214000.0 0.44 641531.0 168000.0 0.36 0.5696 0.9952 1983227 ChemDiv1_028384 COC(=O)C(NC(=O)c1ccccc1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K05 compound treatment 696172.0 214000.0 0.44 626818.0 153000.0 0.33 0.5464 0.99 1983228 ChemDiv1_028385 [O-][N+](=O)c1cc(F)c(cc1N2CCN(CC2)C(=O)c3ccc(F)cc3)N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K06 compound treatment 716240.0 234000.0 0.48 688709.0 215000.0 0.47 0.6704 0.9998 1292273 ChemDiv1_028386 O=C(NCc1cccnc1)c2c(NC(=O)c3cccnc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K07 compound treatment 740202.0 258000.0 0.53 684295.0 211000.0 0.46 0.6987 0.997 1983229 ChemDiv1_028387 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K08 compound treatment 718463.0 236000.0 0.49 643361.0 170000.0 0.37 0.6043 0.9902 1983230 ChemDiv1_028388 COC(=O)C(NC(=O)C)(Nc1ccc(Cl)cn1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K09 compound treatment 719169.0 237000.0 0.49 654186.0 180000.0 0.39 0.6219 0.9938 1341635 ChemDiv1_028389 Cc1ccc(Cn2c(=O)n(C)c3ncn(Cc4ccccc4)c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K10 compound treatment 713728.0 231000.0 0.48 672301.0 199000.0 0.43 0.6417 0.9986 1983231 ChemDiv1_028390 CCCCOc1ccc(cc1)c2nc(NC(=O)CC)c3c(=O)oc4ccccc4c3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K11 compound treatment 745348.0 263000.0 0.54 661831.0 188000.0 0.41 0.6718 0.9899 1572880 ChemDiv1_028391 Cc1c(CC(=O)O)c2C(=O)CC(C)(C)Cc2n1c3ccc(C)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K12 compound treatment 704444.0 222000.0 0.46 652796.0 179000.0 0.39 0.5983 0.9965 1983232 ChemDiv1_028392 COc1cc2CC(C)(C)N=C(NC(Cc3ccccc3)C(=O)O)c2cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K13 compound treatment 735452.0 253000.0 0.52 687248.0 213000.0 0.46 0.6962 0.9981 1983233 ChemDiv1_028393 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K14 compound treatment 881100.0 399000.0 0.82 812983.0 339000.0 0.73 1.1013 0.9984 1320651 ChemDiv1_028394 COc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K15 compound treatment 761767.0 279000.0 0.58 696805.0 223000.0 0.48 0.7493 0.9961 1983234 ChemDiv1_028395 Cc1c(CC(=O)O)c2C(=O)CC(C)(C)Cc2n1c3cc(ccc3Cl)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K16 compound treatment 733028.0 251000.0 0.52 695931.0 222000.0 0.48 0.706 0.9993 1983235 ChemDiv1_028396 CC(=O)C1(C2C(C3c4ccccc41)C(=O)N(C2=O)c5ccc(cc5Br)[N+](=O)[O-])c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K17 compound treatment 754053.0 272000.0 0.56 679262.0 206000.0 0.44 0.7112 0.9934 1983236 ChemDiv1_028397 Cc1c(CC(=O)O)c2C(=O)CC(C)(C)Cc2n1c3cc(ccc3C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K18 compound treatment 726052.0 244000.0 0.5 676547.0 203000.0 0.44 0.6661 0.9977 1983237 ChemDiv1_028398 CN(C)CCN(C)CC(=O)N1c2ccccc2Sc3ccc(cc13)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K19 compound treatment 761124.0 279000.0 0.58 715830.0 242000.0 0.52 0.7775 0.9989 1983238 ChemDiv1_028399 Cc1ccc(cc1)C(O)(C(=O)NN(C(=O)c2ccc(Br)o2)c3ccccc3)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K20 compound treatment 732883.0 251000.0 0.52 661944.0 188000.0 0.41 0.6538 0.993 1983239 ChemDiv1_028400 CC(=O)N1CCN(CC1)C2=NC(=O)/C(=C\c3ccc(OCC=C)cc3)/S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K21 compound treatment 761497.0 279000.0 0.58 682258.0 209000.0 0.45 0.7266 0.9927 1710614 ChemDiv1_028401 COc1cc(ccc1OCc2ccc(Cl)cc2)C3C4=C(CC(C)(C)CC4=O)N(CC(=O)O)C5=C3C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K22 compound treatment 723760.0 241000.0 0.5 679932.0 206000.0 0.45 0.668 0.9985 1514748 ChemDiv1_028402 COc1ccc(cc1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K23 mock treatment 713433.0 231000.0 0.48 677478.0 204000.0 0.44 0.6491 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 K24 mock treatment 266608.0 -216000.0 -0.45 236649.0 -237000.0 -0.51 -0.6777 -0.9975 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L01 compound treatment 641574.0 159000.0 0.33 599849.0 126000.0 0.27 0.4254 0.9957 1719041 ChemDiv1_028403 Cc1cccc(c1)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L02 compound treatment 668672.0 186000.0 0.38 627871.0 154000.0 0.33 0.5079 0.9975 1983240 ChemDiv1_028404 COc1ccc(cc1)N2C(=S)N/C(=N\c3cccc(c3)C(F)(F)F)/C42CCC(CC4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L03 compound treatment 702793.0 220000.0 0.46 685018.0 211000.0 0.46 0.6452 1.0 1983241 ChemDiv1_028405 CCOc1ccccc1C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L04 compound treatment 685486.0 203000.0 0.42 665000.0 191000.0 0.41 0.5893 1.0 1177848 ChemDiv1_028406 CCN1C(=c2sc(=C3C(=NN(C3=O)c4ccc(Cl)cc4)C)n(CC)c2=O)C=Cc5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L05 compound treatment 704439.0 222000.0 0.46 688307.0 215000.0 0.46 0.6526 1.0 1983242 ChemDiv1_028407 Clc1ccc(cc1)c2nnc3cccc(Cl)n23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L06 compound treatment 674024.0 192000.0 0.4 670423.0 197000.0 0.43 0.5808 0.9993 1983243 ChemDiv1_028408 OCCOCCOc1ccc-2c(c1)C(=O)c3cc(OCCOCCO)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L07 compound treatment 688582.0 206000.0 0.43 668168.0 194000.0 0.42 0.5986 1.0 1173492 ChemDiv1_028409 CCCCC(CC)Cn1c(nc2ccccc12)c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L08 compound treatment 701322.0 219000.0 0.45 673808.0 200000.0 0.43 0.6259 0.9998 1578518 ChemDiv1_028410 O=C1Nc2ccc(c3cccc1c23)S(=O)(=O)NC4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L09 compound treatment 710408.0 228000.0 0.47 678961.0 205000.0 0.44 0.647 0.9996 1459427 ChemDiv1_028411 CN1CCC(CC1)(NC(=O)C)NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L10 compound treatment 776290.0 294000.0 0.61 638606.0 165000.0 0.36 0.6814 0.9679 1983244 ChemDiv1_028412 CCCCNS(=O)(=O)c1ccc-2c(Cc3cc(ccc32)S(=O)(=O)NCCCC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L11 compound treatment 713507.0 231000.0 0.48 696418.0 223000.0 0.48 0.6782 1.0 1777512 ChemDiv1_028413 COc1cc(cc2C=CC3(Oc12)N(c4ccccc4C3(C)C)c5ccccc5)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L12 compound treatment 698991.0 217000.0 0.45 677526.0 204000.0 0.44 0.6281 1.0 1694853 ChemDiv1_028414 COC(=O)C1=C(C)NC2(O)c3ccccc3C(=O)C12O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L13 compound treatment 751090.0 269000.0 0.55 680142.0 206000.0 0.45 0.7082 0.9942 1983245 ChemDiv1_028415 CCN(CC)CCOc1cc2C(=NNC(=O)N)c3cc(OCCN(CC)CC)c(Cl)cc3-c2cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L14 compound treatment 707082.0 225000.0 0.46 695770.0 222000.0 0.48 0.6679 0.9998 1983246 ChemDiv1_028416 c1ccc2[nH]c(nc2c1)c3cc4ccccc4n5c6ccccc6nc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L15 compound treatment 693994.0 212000.0 0.44 694413.0 221000.0 0.48 0.6467 0.999 1011369 ChemDiv1_028417 CC1=C(CCC(C)(O)C#C)C(C)(C)CCC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L16 compound treatment 707969.0 226000.0 0.47 698924.0 225000.0 0.49 0.674 0.9997 1983247 ChemDiv1_028418 [O-][N+](=O)c1ccccc1S(=O)(=O)N2c3cccc4cccc(c34)S2(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L17 compound treatment 741505.0 259000.0 0.54 707844.0 234000.0 0.51 0.7366 0.9996 1983248 ChemDiv1_028419 CN(C)CCCSc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L18 compound treatment 704799.0 222000.0 0.46 687934.0 214000.0 0.46 0.6525 1.0 1983249 ChemDiv1_028420 Clc1ccccc1C=c2sc3nnc(c4ccccc4)n3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L19 compound treatment 734350.0 252000.0 0.52 723689.0 250000.0 0.54 0.7504 0.9998 1983250 ChemDiv1_028421 CCc1ccc(NC(c2cc(Cl)cc(Cl)c2OC)P3(=O)OCC(C)(C)CO3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L20 compound treatment 715432.0 233000.0 0.48 679295.0 206000.0 0.44 0.6548 0.9992 1983251 ChemDiv1_028422 CCN(CC)c1c([N+](=O)[O-])c(=O)n(C)c2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L21 compound treatment 864370.0 382000.0 0.79 790702.0 317000.0 0.69 1.0428 0.9976 1983252 ChemDiv1_028423 COP(=O)(OC)C(Nc1cccc2ccccc12)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L22 compound treatment 1839589.0 1360000.0 2.8 1708903.0 1240000.0 2.67 3.8715 0.9997 1983253 ChemDiv1_028424 CCN1/C(=C\C=C\c2n(CC)c3ccc(cc3[n+]2CC)[N+](C)(C)C)/N(CC)c4cc(ccc14)[N+](C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L23 mock treatment 719556.0 237000.0 0.49 672160.0 198000.0 0.43 0.6499 0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 L24 mock treatment 256974.0 -225000.0 -0.47 219988.0 -254000.0 -0.55 -0.7173 -0.9966 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M01 compound treatment 665872.0 184000.0 0.38 571743.0 98000.0 0.21 0.4179 0.9624 1181880 ChemDiv1_028425 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M02 compound treatment 684625.0 202000.0 0.42 605955.0 132000.0 0.29 0.4976 0.983 1983254 ChemDiv1_028426 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M03 compound treatment 739261.0 257000.0 0.53 634225.0 160000.0 0.35 0.6207 0.9789 1983255 ChemDiv1_028427 CC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccc(O)cc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M04 compound treatment 709693.0 227000.0 0.47 639300.0 166000.0 0.36 0.5853 0.9911 1983256 ChemDiv1_028428 COC(=O)C(NC(=O)c1ccc(OC)cc1)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M05 compound treatment 710089.0 228000.0 0.47 646508.0 173000.0 0.37 0.5969 0.9936 1983257 ChemDiv1_028429 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)CN4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M06 compound treatment 705562.0 223000.0 0.46 633471.0 160000.0 0.35 0.5703 0.99 1631232 ChemDiv1_028430 CCC(=O)Nc1nc(C)cc2c3ccccc3oc(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M07 compound treatment 729917.0 248000.0 0.51 670010.0 196000.0 0.42 0.6618 0.9958 1983258 ChemDiv1_028431 CC1(O)N(CCCCCCN2C(=O)OC3(CC(C)(C)NC(C)(C)C3)C2(C)O)C(=O)OC41CC(C)(C)NC(C)(C)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M08 compound treatment 717448.0 235000.0 0.49 652831.0 179000.0 0.39 0.6173 0.9938 1983259 ChemDiv1_028432 COC(=O)C(NC(=O)C)(Nc1ccc(Br)cn1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M09 compound treatment 704208.0 222000.0 0.46 622371.0 149000.0 0.32 0.5513 0.985 1444051 ChemDiv1_028433 Cn1c(=O)n(Cc2ccc(cc2)C(C)(C)C)c(=O)c3n(Cc4ccccc4)cnc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M10 compound treatment 692952.0 211000.0 0.43 638847.0 165000.0 0.36 0.5601 0.9953 1983260 ChemDiv1_028434 CCN1CCN(CC1)C2=NC(=O)/C(=C/c3ccc(OCc4ccccc4)cc3)/S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M11 compound treatment 725043.0 243000.0 0.5 690078.0 216000.0 0.47 0.6854 0.9994 1983261 ChemDiv1_028435 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CCCc2n1c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M12 compound treatment 701863.0 220000.0 0.45 639664.0 166000.0 0.36 0.5744 0.9934 1983262 ChemDiv1_028436 CCCCOc1ccccc1n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M13 compound treatment 692947.0 211000.0 0.43 614001.0 140000.0 0.3 0.5221 0.9846 1983263 ChemDiv1_028437 CCCCn1c(C)c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M14 compound treatment 733524.0 251000.0 0.52 676192.0 202000.0 0.44 0.6765 0.9965 1237474 ChemDiv1_028438 CCOC(=O)c1nnn(c1CN(C)C)c2nonc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M15 compound treatment 715645.0 233000.0 0.48 680444.0 207000.0 0.45 0.6569 0.9993 1983264 ChemDiv1_028439 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M16 compound treatment 711036.0 229000.0 0.47 852473.0 379000.0 0.82 0.9135 0.9657 1308795 ChemDiv1_028440 COc1ccc(cc1)C(O)(C(=O)NN(c2ccccc2)c3ccccc3)c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M17 compound treatment 748962.0 267000.0 0.55 645370.0 172000.0 0.37 0.6519 0.9817 1983265 ChemDiv1_028441 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M18 compound treatment 678026.0 196000.0 0.4 667802.0 194000.0 0.42 0.5827 0.9998 1945034 ChemDiv1_028442 C(Sc1nnc(c2ccco2)n1c3ccccc3)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M19 compound treatment 763557.0 281000.0 0.58 713201.0 239000.0 0.52 0.777 0.9984 1983266 ChemDiv1_028443 COC(=O)C(NC(=O)c1ccccc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M20 compound treatment 741652.0 259000.0 0.54 646777.0 173000.0 0.37 0.6434 0.9847 1983267 ChemDiv1_028444 Clc1ccc(/C=C\2/SC(=NC2=O)N3CCN(CCC#N)CC3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M21 compound treatment 755353.0 273000.0 0.56 693754.0 220000.0 0.48 0.7352 0.9965 1983268 ChemDiv1_028445 COc1ccc2ccccc2c1C3N(Cc4ccc(Cl)cc4)CCN3Cc5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M22 compound treatment 736423.0 254000.0 0.52 659808.0 186000.0 0.4 0.6557 0.9915 1183418 ChemDiv1_028446 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(OC)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M23 mock treatment 711943.0 230000.0 0.47 678746.0 205000.0 0.44 0.6489 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 M24 mock treatment 413034.0 -69300.0 -0.14 444449.0 -29300.0 -0.06 -0.146 -0.933 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N01 compound treatment 641676.0 159000.0 0.33 587990.0 114000.0 0.25 0.4074 0.9901 1473111 ChemDiv1_028447 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4ccc(Br)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N02 compound treatment 660341.0 178000.0 0.37 631329.0 158000.0 0.34 0.501 0.9993 1983269 ChemDiv1_028448 CSC1=N/C(=N\c2ccccc2C)/C3(CCC(CC3)C(C)(C)C)N1c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N03 compound treatment 684033.0 202000.0 0.42 658916.0 185000.0 0.4 0.5778 0.9998 1983270 ChemDiv1_028449 CC1C(C)C(CCN1C)(OC(=O)CCl)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N04 compound treatment 690745.0 208000.0 0.43 654084.0 180000.0 0.39 0.5802 0.9988 1983271 ChemDiv1_028450 [O-][N+](=O)/C(=C(\Nc1cccc2ccccc12)/Sc3ccccc3)/C(=C(Cl)Cl)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N05 compound treatment 689477.0 207000.0 0.43 688282.0 215000.0 0.46 0.6307 0.9992 1534955 ChemDiv1_028451 COc1ccc(C2N(C(=O)C3=C2C(=NCCN3)c4ccccc4)c5ccccc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N06 compound treatment 664775.0 182000.0 0.38 617367.0 144000.0 0.31 0.4861 0.9955 1178975 ChemDiv1_028452 CC(C)CCOc1ccc-2c(c1)C(=O)c3cc(OCCC(C)C)ccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N07 compound treatment 706182.0 224000.0 0.46 671814.0 198000.0 0.43 0.6299 0.9993 1983272 ChemDiv1_028453 CCOC(=O)C1C(C(C(=O)OCC)C(=O)C=C1O)c2ccc(OC)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N08 compound treatment 689822.0 208000.0 0.43 654248.0 180000.0 0.39 0.5791 0.9989 1983273 ChemDiv1_028454 OC(CN1CCN(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)CC1)Cn5c6ccc(Cl)cc6c7cc(Cl)ccc57 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N09 compound treatment 693895.0 212000.0 0.44 712916.0 239000.0 0.52 0.6749 0.9964 1983274 ChemDiv1_028455 O=C1OC(c2ccccc12)(c3ccc(Oc4ccc(C#N)c(C#N)c4)cc3)c5ccc(Oc6ccc(C#N)c(C#N)c6)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N10 compound treatment 680819.0 198000.0 0.41 654568.0 181000.0 0.39 0.5665 0.9997 1983275 ChemDiv1_028456 ON=C1c2cc(cc([N+](=O)[O-])c2-c3c1cc(cc3[N+](=O)[O-])S(=O)(=O)N4CCCCCC4)S(=O)(=O)N5CCCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N11 compound treatment 704666.0 222000.0 0.46 638036.0 164000.0 0.36 0.576 0.992 1425074 ChemDiv1_028457 CC(=O)Nc1ccc2OCCOCCOCCOc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N12 compound treatment 668278.0 186000.0 0.38 657968.0 184000.0 0.4 0.5534 0.9998 1983276 ChemDiv1_028458 Fc1c(F)c(F)c(C2Nc3cccc4cccc(N2)c34)c(F)c1F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N13 compound treatment 631209.0 149000.0 0.31 627181.0 153000.0 0.33 0.4521 0.9993 1983277 ChemDiv1_028459 NC(=S)NN=C1c2cc(OCCN3CCCCC3)ccc2-c4ccc(OCCN5CCCCC5)cc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N14 compound treatment 677336.0 195000.0 0.4 673855.0 200000.0 0.43 0.5909 0.9993 1942841 ChemDiv1_028460 CCOC(=O)c1ccc(/N=C/2\NC(C)(C)Cc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N15 compound treatment 704106.0 222000.0 0.46 692958.0 219000.0 0.47 0.6592 0.9998 1775030 ChemDiv1_028461 CCC(C)(Nc1ccc(C)cc1)c2nnnn2C(/C=C/c3ccc(Cl)cc3Cl)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N16 compound treatment 689245.0 207000.0 0.43 681285.0 208000.0 0.45 0.6197 0.9997 1983278 ChemDiv1_028462 CC(=O)c1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N17 compound treatment 713470.0 231000.0 0.48 724504.0 251000.0 0.54 0.7212 0.9979 1717916 ChemDiv1_028463 CCN(CC)C(=O)CSc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N18 compound treatment 1008335.0 526000.0 1.09 990646.0 517000.0 1.12 1.5589 0.9999 1983279 ChemDiv1_028464 Clc1ccc(/C=C/2\C=C(N(C2=O)c3ccc4ccccc4c3)c5ccccc5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N19 compound treatment 737104.0 255000.0 0.53 699801.0 226000.0 0.49 0.7179 0.9993 1983280 ChemDiv1_028465 CCN/1C(=C(C)S\C1=C\2/SC(=S)N(NC(=O)C)C2=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N20 compound treatment 706776.0 224000.0 0.46 687811.0 214000.0 0.46 0.6552 1.0 1678335 ChemDiv1_028466 COc1ccc(cc1OC)C(=O)Nc2sc3CCCCc3c2c4nc5ccccc5s4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N21 compound treatment 756466.0 274000.0 0.57 711193.0 237000.0 0.51 0.7636 0.9988 1983281 ChemDiv1_028467 COc1c(Cl)cc(Cl)cc1C(Nc2cccc3ccccc23)P4(=O)OCC(C)(C)CO4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N22 compound treatment 704388.0 222000.0 0.46 664711.0 191000.0 0.41 0.6164 0.9987 1279528 ChemDiv1_028468 Cc1nc(c(o1)N2CCOCC2)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N23 mock treatment 691587.0 209000.0 0.43 686247.0 212000.0 0.46 0.6307 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 N24 mock treatment 163756.0 -319000.0 -0.66 413149.0 -60600.0 -0.13 -0.5578 -0.8318 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O01 compound treatment 640522.0 158000.0 0.33 558757.0 85000.0 0.18 0.361 0.9631 1983282 ChemDiv1_028469 FC(F)(F)c1cccc(c1)C2N(Cc3ccc(Cl)cc3)CCN2Cc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O02 compound treatment 661409.0 179000.0 0.37 615465.0 142000.0 0.31 0.4783 0.9957 1983283 ChemDiv1_028470 COC(=O)C1=NN(c2ccc(OC)cc2)C3(Nc4ccccc4S3)S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O03 compound treatment 689024.0 207000.0 0.43 634779.0 161000.0 0.35 0.5482 0.995 1983284 ChemDiv1_028471 CSCCC1(NC(C2C1C(=O)N(C2=O)c3ccc(Br)cc3)c4ccccc4O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O04 compound treatment 659785.0 177000.0 0.37 590328.0 117000.0 0.25 0.4375 0.9834 1983285 ChemDiv1_028472 COC(=O)C(NC(=O)c1ccccc1OC)(Nc2sc3CC(CCc3c2C#N)C(C)(C)C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O05 compound treatment 697979.0 216000.0 0.45 609095.0 135000.0 0.29 0.5219 0.9794 1526252 ChemDiv1_028473 Oc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O06 compound treatment 664601.0 182000.0 0.38 589668.0 116000.0 0.25 0.4435 0.9806 1491719 ChemDiv1_028474 CC(=O)N1c2ccccc2CCc3ccc(NC(=O)CCC4CCCC4)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O07 compound treatment 695991.0 214000.0 0.44 627756.0 154000.0 0.33 0.5476 0.9905 1128950 ChemDiv1_028475 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O08 compound treatment 692222.0 210000.0 0.43 630615.0 157000.0 0.34 0.5465 0.9927 1983286 ChemDiv1_028476 COC(=O)C(NC(=O)c1ccc(OC)cc1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O09 compound treatment 708483.0 226000.0 0.47 629439.0 156000.0 0.34 0.5684 0.9872 1255117 ChemDiv1_028477 Cn1c(=O)n(Cc2cccc(Cl)c2)c(=O)c3n(Cc4ccccc4)cnc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O10 compound treatment 678149.0 196000.0 0.4 603590.0 130000.0 0.28 0.4846 0.9842 1983287 ChemDiv1_028478 CCOCCOC(=O)C1=C(C)NC(=O)CC1c2cccc(Cl)c2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O11 compound treatment 774700.0 292000.0 0.6 643199.0 169000.0 0.37 0.6861 0.9715 1983288 ChemDiv1_028479 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1CCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O12 compound treatment 640573.0 158000.0 0.33 595261.0 122000.0 0.26 0.417 0.9942 1513953 ChemDiv1_028480 COc1ccc(cc1OC)n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O13 compound treatment 701184.0 219000.0 0.45 628406.0 155000.0 0.33 0.5562 0.9891 1983289 ChemDiv1_028481 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CCCc2n1N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O14 compound treatment 732382.0 250000.0 0.52 645772.0 172000.0 0.37 0.6283 0.9871 1983290 ChemDiv1_028482 CCN1CCN(CC1)C2=NC(=O)/C(=C\c3ccc(OC)cc3)/S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O15 compound treatment 735402.0 253000.0 0.52 660874.0 187000.0 0.41 0.6558 0.9921 1983291 ChemDiv1_028483 Cc1c(CC(Cl)(Cl)Cl)c2C(=O)CC(C)(C)Cc2n1c3ccc(OC(F)(F)F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O16 compound treatment 689364.0 207000.0 0.43 609141.0 135000.0 0.29 0.5094 0.983 1983292 ChemDiv1_028484 CCCCC(O)(CCCC)C1=NN(C(=O)C(O1)(c2ccccc2)c3ccccc3)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O17 compound treatment 721941.0 240000.0 0.49 679209.0 205000.0 0.44 0.6642 0.9986 1619640 ChemDiv1_028485 Cc1c(CC(=O)O)c2C(=O)CCCc2n1c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O18 compound treatment 683747.0 201000.0 0.42 639533.0 166000.0 0.36 0.5477 0.9973 1715646 ChemDiv1_028486 COc1cccc(c1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccc(C)c(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O19 compound treatment 725796.0 243000.0 0.5 677051.0 203000.0 0.44 0.6665 0.9978 1983293 ChemDiv1_028487 COC(=O)C(NC(=O)c1cccc(Cl)c1)(Nc2sc3CC(C)CCc3c2C#N)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O20 compound treatment 740457.0 258000.0 0.53 624130.0 150000.0 0.33 0.6069 0.972 1983294 ChemDiv1_028488 CC(C)Oc1ccccc1/C=C\2/SC(=NC2=O)N3CCN(CC3)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O21 compound treatment 699923.0 218000.0 0.45 649462.0 176000.0 0.38 0.5865 0.9966 1983295 ChemDiv1_028489 COc1cc(C2N(Cc3ccccc3)CCCN2Cc4ccccc4)c(cc1OC)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O22 compound treatment 694079.0 212000.0 0.44 628029.0 154000.0 0.33 0.5452 0.9912 1441641 ChemDiv1_028490 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O23 mock treatment 697521.0 215000.0 0.44 621594.0 148000.0 0.32 0.5404 0.987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 O24 mock treatment 188542.0 -294000.0 -0.61 299720.0 -174000.0 -0.38 -0.6952 -0.9738 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P01 compound treatment 604255.0 122000.0 0.25 591917.0 118000.0 0.26 0.3588 1.0 1366559 ChemDiv1_028491 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2c5cccc(C)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P02 compound treatment 641885.0 160000.0 0.33 572588.0 98800.0 0.21 0.3842 0.9782 1983296 ChemDiv1_028492 CSC1=N/C(=N\c2ccccc2C)/C3(CCC(CC3)C(C)(C)C)N1c4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P03 compound treatment 644061.0 162000.0 0.33 584450.0 111000.0 0.24 0.4055 0.9868 1303270 ChemDiv1_028493 CCCCC1(Nc2ccc(C)cc2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P04 compound treatment 636832.0 155000.0 0.32 567560.0 93800.0 0.2 0.3691 0.9762 1183517 ChemDiv1_028494 CCC1C(NC(CC1(O)Cc2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P05 compound treatment 642073.0 160000.0 0.33 571977.0 98200.0 0.21 0.3835 0.9774 1983297 ChemDiv1_028495 CCOC(=O)C1C(NC(=S)NC1(C)O)c2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P06 compound treatment 637278.0 155000.0 0.32 587461.0 114000.0 0.25 0.4002 0.9916 1983298 ChemDiv1_028496 CCOP(=O)(OCC)c1nc(oc1N2CCOCC2)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P07 compound treatment 626513.0 144000.0 0.3 587378.0 114000.0 0.25 0.3844 0.9955 1983299 ChemDiv1_028497 CCOC(=O)C1C(C(C(=O)OCC)C(=O)C=C1C)c2ccc(OC)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P08 compound treatment 634042.0 152000.0 0.31 599477.0 126000.0 0.27 0.4139 0.9975 1944945 ChemDiv1_028498 CC(C)OP(=O)(OC(C)C)C(Nc1ccc(Br)cc1)c2ccc(O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P09 compound treatment 639351.0 157000.0 0.32 611964.0 138000.0 0.3 0.4407 0.9992 1534215 ChemDiv1_028499 CN1c2ccccc2C(C)(C)C31Oc4ccc5ccccc5c4N=C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P10 compound treatment 648367.0 166000.0 0.34 585401.0 112000.0 0.24 0.4133 0.9854 1983300 ChemDiv1_028500 [O-][N+](=O)c1cc(cc2C(=O)c3cc(cc([N+](=O)[O-])c3-c21)S(=O)(=O)N4CCCCCC4)S(=O)(=O)N5CCCCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P11 compound treatment 625559.0 143000.0 0.3 583881.0 110000.0 0.24 0.3776 0.9943 1983301 ChemDiv1_028501 CC(C)CCCC(C)C1CCC2C3CC=C4CC(CCC4(C)C3CCC12C)OC(=O)C5CCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P12 compound treatment 599682.0 117000.0 0.24 593585.0 120000.0 0.26 0.3547 0.9994 1362371 ChemDiv1_028502 COc1ccc(cc1O)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P13 compound treatment 3.610266E7 3.56E7 73.53 3.42466E7 3.38E7 73.1 103.6822 1.0 1391190 ChemDiv1_028503 OCCNc1ccc2c(=O)n3c4ccccc4nc3c5cccc1c25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P14 compound treatment 648515.0 166000.0 0.34 600671.0 127000.0 0.27 0.4368 0.9939 1983302 ChemDiv1_028504 O=C(Sc1sc(=S)sc1SC(=O)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P15 compound treatment 666474.0 184000.0 0.38 610655.0 137000.0 0.3 0.4783 0.9924 1103083 ChemDiv1_028505 COc1ccc(cc1)C2N(CCN2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P16 compound treatment 661708.0 179000.0 0.37 617912.0 144000.0 0.31 0.4825 0.9964 1983303 ChemDiv1_028506 CCCSc1nnc2c3ccccc3n(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P17 compound treatment 680383.0 198000.0 0.41 623626.0 150000.0 0.32 0.5185 0.9934 1983304 ChemDiv1_028507 COc1ccccc1/C=C/2\CCC/C(=C\c3ccccc3OC)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P18 compound treatment 652575.0 170000.0 0.35 634788.0 161000.0 0.35 0.495 1.0 1779362 ChemDiv1_028508 COc1cc(C2N(Cc3ccccc3)CCN2Cc4ccccc4)c(cc1OC)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P19 compound treatment 678918.0 197000.0 0.41 625158.0 151000.0 0.33 0.5187 0.9944 1216755 ChemDiv1_028509 OCC1OC(C(O)C1O)n2c(NCc3ccccc3)nc4c(=O)[nH]cnc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P20 compound treatment 666902.0 185000.0 0.38 628758.0 155000.0 0.34 0.5067 0.998 1344784 ChemDiv1_028510 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P21 compound treatment 651057.0 169000.0 0.35 606004.0 132000.0 0.29 0.4487 0.9952 1476173 ChemDiv1_028511 Cc1nc2CCCC(=O)c2c3c4ccccc4[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P22 compound treatment 630475.0 148000.0 0.31 592611.0 119000.0 0.26 0.3982 0.9963 1983305 ChemDiv1_028512 Cc1ccc(cc1)[N+]2=C3CCCCCN3CC2(O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P23 mock treatment 621414.0 139000.0 0.29 593020.0 119000.0 0.26 0.3856 0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.667 P24 mock treatment 465958.0 -16400.0 -0.03 451444.0 -22300.0 -0.05 -0.058 -0.9847 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A01 compound treatment 612349.0 148000.0 0.31 535908.0 101000.0 0.22 0.3706 0.9866 1640911 ChemDiv1_028513 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A02 compound treatment 625846.0 161000.0 0.33 523174.0 88300.0 0.19 0.3708 0.9652 1134700 ChemDiv1_028514 Cc1ccc(C)c(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(Cl)cc3Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A03 compound treatment 627258.0 163000.0 0.34 539768.0 105000.0 0.23 0.3983 0.9818 1613748 ChemDiv1_028515 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2c(C)cc(C)cc2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A04 compound treatment 653667.0 189000.0 0.39 531940.0 97100.0 0.21 0.4248 0.9577 1727956 ChemDiv1_028516 CCc1ccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A05 compound treatment 643044.0 179000.0 0.37 545310.0 110000.0 0.24 0.4298 0.978 1164432 ChemDiv1_028517 Cc1cccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(Cl)cc3Cl)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A06 compound treatment 649672.0 185000.0 0.38 560490.0 126000.0 0.27 0.4627 0.986 1163779 ChemDiv1_028518 CCc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A07 compound treatment 672568.0 208000.0 0.43 572662.0 138000.0 0.3 0.5147 0.9841 1258985 ChemDiv1_028519 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A08 compound treatment 648558.0 184000.0 0.38 616740.0 182000.0 0.39 0.5472 0.9998 1482825 ChemDiv1_028520 COc1ccc(cc1)C(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A09 compound treatment 639410.0 175000.0 0.36 580192.0 145000.0 0.31 0.4779 0.9976 1727298 ChemDiv1_028521 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)c(Cl)c2)C#N)c3cc(OC)c(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A10 compound treatment 661177.0 197000.0 0.41 577191.0 142000.0 0.31 0.5051 0.9907 1237975 ChemDiv1_028522 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccc(C)c(C)c4)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A11 compound treatment 683500.0 219000.0 0.45 589675.0 155000.0 0.34 0.5567 0.9891 1675504 ChemDiv1_028523 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)Nc4cc(OC)c(Cl)cc4OC)c(N)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A12 compound treatment 691136.0 227000.0 0.47 578009.0 143000.0 0.31 0.55 0.9799 1983306 ChemDiv1_028524 OC(=O)COc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A13 compound treatment 673229.0 209000.0 0.43 576177.0 141000.0 0.31 0.5211 0.9859 1983307 ChemDiv1_028525 COc1ccc(cc1OC)c2c(C#N)c(SCC(=O)N)nc(C)c2C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A14 compound treatment 693869.0 229000.0 0.47 601885.0 167000.0 0.36 0.5906 0.9911 1983308 ChemDiv1_028526 CN(C)c1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A15 compound treatment 688950.0 225000.0 0.46 596122.0 161000.0 0.35 0.5746 0.9902 1172700 ChemDiv1_028527 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A16 compound treatment 669187.0 205000.0 0.42 574918.0 140000.0 0.3 0.5133 0.9867 1572343 ChemDiv1_028528 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3nnc[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A17 compound treatment 700706.0 236000.0 0.49 601858.0 167000.0 0.36 0.6005 0.9891 1325198 ChemDiv1_028529 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A18 compound treatment 672156.0 208000.0 0.43 597703.0 163000.0 0.35 0.5525 0.9953 1983309 ChemDiv1_028530 CCOC(=O)C(Sc1ncn[nH]1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A19 compound treatment 669488.0 205000.0 0.42 591823.0 157000.0 0.34 0.5396 0.9941 1252482 ChemDiv1_028531 CCc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A20 compound treatment 658952.0 195000.0 0.4 571083.0 136000.0 0.29 0.4925 0.9885 1983310 ChemDiv1_028532 C(CNc1ncnc2ccccc12)CNc3ncnc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A21 compound treatment 632301.0 168000.0 0.35 561344.0 126000.0 0.27 0.4387 0.9932 1315856 ChemDiv1_028533 Cc1ccccc1NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A22 compound treatment 605081.0 141000.0 0.29 570921.0 136000.0 0.29 0.4136 1.0 1387008 ChemDiv1_028534 Brc1ccccc1Oc2coc3cc(OC(=O)c4cccs4)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A23 mock treatment 600510.0 136000.0 0.28 537130.0 102000.0 0.22 0.3552 0.993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 A24 mock treatment 199150.0 -265000.0 -0.55 217465.0 -217000.0 -0.47 -0.7199 -0.9971 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B01 compound treatment 636412.0 172000.0 0.36 543627.0 109000.0 0.24 0.4175 0.9801 1983311 ChemDiv1_028535 CN(C)c1ccc(cc1)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B02 compound treatment 685768.0 221000.0 0.46 553244.0 118000.0 0.26 0.5043 0.9626 1258853 ChemDiv1_028536 O=c1cccc2C3CC(CN(C3)C(=S)NC4CCCCC4)Cn21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B03 compound treatment 783939.0 320000.0 0.66 645107.0 210000.0 0.46 0.7882 0.9836 1217631 ChemDiv1_028537 CCOC(=O)COc1cc(Br)c(cc1OC)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B04 compound treatment 699852.0 235000.0 0.49 589340.0 154000.0 0.33 0.5801 0.9833 1551128 ChemDiv1_028538 Cc1ccccc1Nc2nc(cs2)C3(C)CC4(CC(C)(C)OC4=O)C(=O)O3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B05 compound treatment 726888.0 262000.0 0.54 613821.0 179000.0 0.39 0.657 0.9865 1578424 ChemDiv1_028539 COc1ccc(cc1)N2C3=C(C(C4=C2CC(C)(C)CC4=O)c5ccccc5)C(=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B06 compound treatment 727590.0 263000.0 0.54 596388.0 162000.0 0.35 0.6314 0.9773 1340746 ChemDiv1_028540 CC(C)C1(CN2CC3(CN(C1)C2c4c[nH]c5ccccc45)C(C)C)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B07 compound treatment 731899.0 267000.0 0.55 630833.0 196000.0 0.42 0.6904 0.9915 1602419 ChemDiv1_028541 CC(NC(=O)CSc1nnc2c3ccccc3[nH]c2n1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B08 compound treatment 734355.0 270000.0 0.56 616598.0 182000.0 0.39 0.6722 0.9855 1983312 ChemDiv1_028542 CC1(C)N2CC3(CN1CC(C2)([N+](=O)[O-])C3(C)C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B09 compound treatment 752718.0 288000.0 0.6 645690.0 211000.0 0.46 0.7435 0.9914 1227625 ChemDiv1_028543 Cc1ccc(c(C)c1)S(=O)(=O)Nc2cc3c4C(=O)CC(C)(C)Cc4oc3c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B10 compound treatment 730161.0 266000.0 0.55 635206.0 200000.0 0.43 0.6945 0.9932 1269522 ChemDiv1_028544 Cc1ccc(cc1C)S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(C)c(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B11 compound treatment 747651.0 283000.0 0.58 648672.0 214000.0 0.46 0.7407 0.9933 1221093 ChemDiv1_028545 COc1ccc(CC(=O)NCC2(CCOCC2)c3ccc(OC)c(OC)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B12 compound treatment 712553.0 248000.0 0.51 622902.0 188000.0 0.41 0.65 0.9935 1716934 ChemDiv1_028546 O=C(N1CCOCC1)C2(CCC(=O)N2Cc3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B13 compound treatment 754379.0 290000.0 0.6 655216.0 220000.0 0.48 0.7605 0.9937 1555568 ChemDiv1_028547 Cc1ccc(cc1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(Br)s5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B14 compound treatment 744525.0 280000.0 0.58 636844.0 202000.0 0.44 0.718 0.9905 1983313 ChemDiv1_028548 Ic1ccc(cc1)C2=Nc3ccccc3N(C(C2)c4ccccc4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B15 compound treatment 761377.0 297000.0 0.61 670573.0 236000.0 0.51 0.7942 0.9958 1983314 ChemDiv1_028549 CCOc1ccc(cc1)C2C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C(=O)N2c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B16 compound treatment 747651.0 283000.0 0.58 658763.0 224000.0 0.48 0.7561 0.9957 1983315 ChemDiv1_028550 Clc1ccc(cc1)S(=O)(=O)c2nc(/C=C/c3ccccc3)oc2NCc4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B17 compound treatment 761335.0 297000.0 0.61 660856.0 226000.0 0.49 0.7793 0.9938 1475437 ChemDiv1_028551 CC1(C)Cc2ccccc2-c3nc4SCCn4c(=O)c31 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B18 compound treatment 702148.0 238000.0 0.49 628521.0 194000.0 0.42 0.6434 0.9969 1450253 ChemDiv1_028552 OC(=O)c1cn(c2ccccc2)c3cc(N4CCNCC4)c(F)cc3c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B19 compound treatment 743572.0 279000.0 0.58 653251.0 218000.0 0.47 0.7417 0.9952 1454166 ChemDiv1_028553 Cc1sc2c(=O)n3CCCCCc3nc2c1C(=O)NCCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B20 compound treatment 700823.0 236000.0 0.49 622175.0 187000.0 0.41 0.6318 0.9958 1626294 ChemDiv1_028554 CC(C)(C)NC(=O)CSc1nnc(c2ccccc2)c(n1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B21 compound treatment 716894.0 252000.0 0.52 624761.0 190000.0 0.41 0.6592 0.9931 1473200 ChemDiv1_028555 CCOc1ccccc1NC(=O)c2c(NC(=O)c3ccccc3C)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B22 compound treatment 683698.0 219000.0 0.45 589045.0 154000.0 0.33 0.5561 0.9888 1983316 ChemDiv1_028556 Clc1ccc2nc(nc(c3ccccc3)c2c1)c4cc5ccccc5oc4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B23 mock treatment 671249.0 207000.0 0.43 584101.0 149000.0 0.32 0.5303 0.9905 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 B24 mock treatment 277436.0 -187000.0 -0.39 215297.0 -220000.0 -0.48 -0.6089 -0.9947 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C01 compound treatment 642616.0 178000.0 0.37 539217.0 104000.0 0.23 0.4198 0.9726 1465804 ChemDiv1_028557 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C02 compound treatment 669270.0 205000.0 0.42 557746.0 123000.0 0.27 0.4871 0.975 1658065 ChemDiv1_028558 CC(=O)Nc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C03 compound treatment 722351.0 258000.0 0.53 619757.0 185000.0 0.4 0.6595 0.9901 1227228 ChemDiv1_028559 Nc1c(sc2nc3CCCCc3c(c4ccco4)c12)C(=O)Nc5cccc(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C04 compound treatment 711733.0 247000.0 0.51 606667.0 172000.0 0.37 0.624 0.9879 1393679 ChemDiv1_028560 Cc1ccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C05 compound treatment 719202.0 255000.0 0.53 619202.0 184000.0 0.4 0.654 0.9907 1740205 ChemDiv1_028561 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C06 compound treatment 702946.0 239000.0 0.49 589726.0 155000.0 0.34 0.5852 0.9824 1170990 ChemDiv1_028562 O=C(CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)NCc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C07 compound treatment 738791.0 274000.0 0.57 627825.0 193000.0 0.42 0.6958 0.9888 1241939 ChemDiv1_028563 COc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC(C)C)c3ccc(Cl)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C08 compound treatment 729174.0 265000.0 0.55 637076.0 202000.0 0.44 0.696 0.9939 1983317 ChemDiv1_028564 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3cccs3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C09 compound treatment 756862.0 292000.0 0.6 643250.0 208000.0 0.45 0.7458 0.9897 1509316 ChemDiv1_028565 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C10 compound treatment 747205.0 283000.0 0.58 619785.0 185000.0 0.4 0.6958 0.9831 1368996 ChemDiv1_028566 Cc1ccc(Cl)cc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C11 compound treatment 757462.0 293000.0 0.6 646548.0 212000.0 0.46 0.7517 0.9906 1412738 ChemDiv1_028567 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(Cl)cc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C12 compound treatment 707456.0 243000.0 0.5 625433.0 191000.0 0.41 0.6464 0.9953 1983318 ChemDiv1_028568 [O-][N+](=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=O)NC(=S)N(CC=C)C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C13 compound treatment 842060.0 378000.0 0.78 704841.0 270000.0 0.58 0.9644 0.9899 1554664 ChemDiv1_028569 COc1cccc(NC(=O)c2sc3nc(N)c(C#N)c(c4ccc(cc4)C(C)C)c3c2N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C14 compound treatment 748945.0 285000.0 0.59 666985.0 232000.0 0.5 0.7706 0.997 1983319 ChemDiv1_028570 Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1c5ccc(Cl)c(Cl)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C15 compound treatment 775971.0 312000.0 0.64 676766.0 242000.0 0.52 0.825 0.9948 1983320 ChemDiv1_028571 CC(=O)c1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C16 compound treatment 781559.0 317000.0 0.65 665504.0 231000.0 0.5 0.8159 0.991 1478999 ChemDiv1_028572 COC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C17 compound treatment 755973.0 292000.0 0.6 658587.0 224000.0 0.48 0.768 0.9942 1494297 ChemDiv1_028573 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C18 compound treatment 702634.0 238000.0 0.49 630957.0 196000.0 0.42 0.6479 0.9973 1321517 ChemDiv1_028574 Clc1cccc(Nc2ncnc3ccc(Br)cc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C19 compound treatment 743939.0 280000.0 0.58 642492.0 208000.0 0.45 0.7258 0.9924 1570535 ChemDiv1_028575 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C20 compound treatment 715405.0 251000.0 0.52 638323.0 203000.0 0.44 0.6778 0.9967 1983321 ChemDiv1_028576 C(CNc1nc(nc2ccccc12)c3ccccc3)CN4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C21 compound treatment 736137.0 272000.0 0.56 631176.0 196000.0 0.42 0.6971 0.9906 1446468 ChemDiv1_028577 Cc1cccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C22 compound treatment 698161.0 234000.0 0.48 612866.0 178000.0 0.39 0.6136 0.9938 1300279 ChemDiv1_028578 COc1ccc(Oc2coc3cc(OC(=O)c4ccc(Br)cc4)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C23 mock treatment 680612.0 216000.0 0.45 610108.0 175000.0 0.38 0.5838 0.9967 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 C24 mock treatment 208972.0 -255000.0 -0.53 204407.0 -230000.0 -0.5 -0.7256 -0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D01 compound treatment 629636.0 165000.0 0.34 551896.0 117000.0 0.25 0.4203 0.9893 1919315 ChemDiv1_028579 Cc1c(C(c2c(C)n(C)n(c3ccccc3)c2=O)c4ccccc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D02 compound treatment 684649.0 220000.0 0.45 564959.0 130000.0 0.28 0.5206 0.9735 1983322 ChemDiv1_028580 CCN(CC)CCN1C2=NCCN2c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D03 compound treatment 718714.0 254000.0 0.52 604297.0 169000.0 0.37 0.6305 0.9846 1457259 ChemDiv1_028581 Fc1ccccc1C(=O)Nc2sc3CCCCCc3c2C(=O)Nc4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D04 compound treatment 608339.0 144000.0 0.3 528709.0 93900.0 0.2 0.3537 0.9828 1241116 ChemDiv1_028582 CCOc1cc(ccc1O)C2C3=C(NC4=C2C(=O)CC(C)(C)C4)c5ccccc5C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D05 compound treatment 705444.0 241000.0 0.5 620938.0 186000.0 0.4 0.6366 0.9945 1983323 ChemDiv1_028583 CC1(C)CC(=O)C2=C(C1)N(C3=C(C2c4ccccc4)C(=O)c5ccccc35)c6ccccc6F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D06 compound treatment 727568.0 263000.0 0.54 622287.0 187000.0 0.41 0.671 0.9897 1983324 ChemDiv1_028584 CCCC(=O)N(c1ccc2oc(C)c(C(=O)C)c2c1)S(=O)(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D07 compound treatment 706719.0 242000.0 0.5 641134.0 206000.0 0.45 0.6694 0.9984 1614286 ChemDiv1_028585 Cc1nc(N2CCCCC2)c3oc4ccccc4c3n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D08 compound treatment 716361.0 252000.0 0.52 633055.0 198000.0 0.43 0.6711 0.9954 1378600 ChemDiv1_028586 CNS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D09 compound treatment 742018.0 278000.0 0.57 654967.0 220000.0 0.48 0.7421 0.9958 1864640 ChemDiv1_028587 CC(C)(C)C1CCc2oc3ccc(NS(=O)(=O)c4ccc(cc4)C(C)(C)C)cc3c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D10 compound treatment 723793.0 259000.0 0.54 646080.0 211000.0 0.46 0.7019 0.9969 1983325 ChemDiv1_028588 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D11 compound treatment 757504.0 293000.0 0.61 686266.0 251000.0 0.54 0.8126 0.9986 1776654 ChemDiv1_028589 Cc1ccc(cc1)S(=O)(=O)N2CN3CC(C2)(CN(CC3)S(=O)(=O)c4ccc(C)cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D12 compound treatment 701113.0 237000.0 0.49 609818.0 175000.0 0.38 0.6133 0.9921 1599862 ChemDiv1_028590 CCn1cnc2sc(C(=O)N3CCC(=O)CC3)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D13 compound treatment 756809.0 292000.0 0.6 686632.0 252000.0 0.54 0.8121 0.9987 1944274 ChemDiv1_028591 CC1(C)N(C(=O)c2ccc(F)cc2)c3ccccc3N(Cc4ccc(cc4)[N+](=O)[O-])C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D14 compound treatment 689408.0 225000.0 0.46 637265.0 202000.0 0.44 0.6382 0.9996 1393981 ChemDiv1_028592 CC(=O)OC1CCCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D15 compound treatment 789195.0 325000.0 0.67 695284.0 260000.0 0.56 0.8727 0.9963 1521065 ChemDiv1_028593 CN1C2CCC1CC(C2)NC(=O)CCN3CCCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D16 compound treatment 733657.0 269000.0 0.56 653189.0 218000.0 0.47 0.7272 0.9967 1031007 ChemDiv1_028594 [O-][N+]1=C(c2ccccc2)c3cc(Cl)ccc3NC(=O)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D17 compound treatment 744473.0 280000.0 0.58 687414.0 253000.0 0.55 0.7953 0.9996 1983326 ChemDiv1_028595 Clc1ccc(cc1)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D18 compound treatment 680953.0 217000.0 0.45 638547.0 204000.0 0.44 0.6278 1.0 1983327 ChemDiv1_028596 CC(C)N(CCOC(=O)C1(CCOc2ccccc21)c3ccccc3)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D19 compound treatment 764507.0 300000.0 0.62 686774.0 252000.0 0.55 0.8236 0.998 1372907 ChemDiv1_028597 COc1cc(ccc1O)C2N(C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4nncs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D20 compound treatment 744100.0 280000.0 0.58 668283.0 233000.0 0.51 0.7655 0.9978 1983328 ChemDiv1_028598 CC(=O)c1c(C)oc2c1cc(O)c3n(nc(c4ccc(cc4)[N+](=O)[O-])c23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D21 compound treatment 730177.0 266000.0 0.55 657591.0 223000.0 0.48 0.7288 0.9979 1983329 ChemDiv1_028599 COc1cccc(C(c2c(C)nn(c2O)c3ccccc3)c4c(C)nn(c4O)c5ccccc5)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D22 compound treatment 693530.0 229000.0 0.47 686754.0 252000.0 0.55 0.72 0.9975 1983330 ChemDiv1_028600 Clc1ccc2oc(=O)c(cc2c1)c3nc(c4ccccc4)c5cc(Cl)ccc5n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D23 mock treatment 694528.0 230000.0 0.48 618494.0 184000.0 0.4 0.6169 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 D24 mock treatment 225716.0 -239000.0 -0.49 221989.0 -213000.0 -0.46 -0.6742 -0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E01 compound treatment 646166.0 182000.0 0.38 552288.0 117000.0 0.25 0.445 0.982 1652286 ChemDiv1_028601 COc1cc(ccc1OCc2ccccc2)C3CC(=O)NC(=C3C#N)SCC(=O)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E02 compound treatment 646728.0 182000.0 0.38 555495.0 121000.0 0.26 0.4508 0.9841 1661818 ChemDiv1_028602 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(C(=O)OC)C(=O)N2)c3ccccc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E03 compound treatment 734545.0 270000.0 0.56 592615.0 158000.0 0.34 0.6358 0.9723 1185364 ChemDiv1_028603 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2c(C)cc(C)cc2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E04 compound treatment 698242.0 234000.0 0.48 599790.0 165000.0 0.36 0.5937 0.989 1623829 ChemDiv1_028604 Cc1cc(C)c(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E05 compound treatment 742548.0 278000.0 0.57 624902.0 190000.0 0.41 0.6968 0.9866 1244028 ChemDiv1_028605 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(CC)cc2)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E06 compound treatment 732205.0 268000.0 0.55 653561.0 219000.0 0.47 0.7256 0.997 1276251 ChemDiv1_028606 CCOc1ccc(NC(=O)c2sc3nc4CCCCc4c(c5ccco5)c3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E07 compound treatment 736440.0 272000.0 0.56 636588.0 202000.0 0.44 0.7058 0.9923 1711529 ChemDiv1_028607 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(F)cc2)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E08 compound treatment 742778.0 278000.0 0.57 639915.0 205000.0 0.44 0.7202 0.9919 1319099 ChemDiv1_028608 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2cccs2)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E09 compound treatment 740673.0 276000.0 0.57 606736.0 172000.0 0.37 0.6663 0.9786 1474983 ChemDiv1_028609 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3ccco3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E10 compound treatment 738865.0 274000.0 0.57 593779.0 159000.0 0.34 0.6438 0.9714 1399088 ChemDiv1_028610 CC(=O)Nc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E11 compound treatment 772283.0 308000.0 0.64 669313.0 234000.0 0.51 0.8082 0.9938 1148826 ChemDiv1_028611 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E12 compound treatment 715612.0 251000.0 0.52 646629.0 212000.0 0.46 0.6908 0.9981 1983331 ChemDiv1_028612 CC1=NN(C(=O)C1/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E13 compound treatment 973272.0 509000.0 1.05 832249.0 397000.0 0.86 1.351 0.9951 1163720 ChemDiv1_028613 Nc1c(sc2nc3CCCCc3c(c4ccco4)c12)C(=O)Nc5nccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E14 compound treatment 724732.0 260000.0 0.54 644448.0 210000.0 0.45 0.7008 0.9965 1983332 ChemDiv1_028614 CCOC(=O)COc1c(Br)cc(/C=C/2\SC(=O)N(C)C2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E15 compound treatment 769377.0 305000.0 0.63 684572.0 250000.0 0.54 0.8273 0.9971 1547716 ChemDiv1_028615 Nc1c(sc2nc3CCCCc3c(c4ccco4)c12)C(=O)Nc5cccc(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E16 compound treatment 716176.0 252000.0 0.52 635406.0 201000.0 0.43 0.6744 0.996 1983333 ChemDiv1_028616 COc1ccc(Oc2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E17 compound treatment 752208.0 288000.0 0.59 683243.0 248000.0 0.54 0.8002 0.9988 1144067 ChemDiv1_028617 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(C)cc2C)C#N)c3ccco3)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E18 compound treatment 734540.0 270000.0 0.56 661263.0 226000.0 0.49 0.7408 0.9979 1164201 ChemDiv1_028618 Clc1ccc(Nc2ncnc3ccc(Br)cc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E19 compound treatment 767736.0 303000.0 0.63 673681.0 239000.0 0.52 0.8083 0.9955 1601346 ChemDiv1_028619 Cc1cc(C)c(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E20 compound treatment 719057.0 255000.0 0.53 638268.0 203000.0 0.44 0.683 0.9961 1332465 ChemDiv1_028620 CC1(CC2CC(C)(C)C1)CN2c3ncnc4ccc(Br)cc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E21 compound treatment 753576.0 289000.0 0.6 644139.0 209000.0 0.45 0.7424 0.9907 1726177 ChemDiv1_028621 Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E22 compound treatment 731400.0 267000.0 0.55 615508.0 181000.0 0.39 0.6662 0.9859 1376058 ChemDiv1_028622 COc1ccc(Oc2coc3cc(OC(=O)c4ccc(OC)c(OC)c4)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E23 mock treatment 694808.0 230000.0 0.48 603926.0 169000.0 0.37 0.5951 0.9916 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 E24 mock treatment 226355.0 -238000.0 -0.49 218868.0 -216000.0 -0.47 -0.678 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F01 compound treatment 634254.0 170000.0 0.35 555067.0 120000.0 0.26 0.4319 0.9892 1983334 ChemDiv1_028623 CN(Cc1ccccc1)c2ccn(c3nc(oc3c4ccccc4)c5ccccc5)c(=O)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F02 compound treatment 675445.0 211000.0 0.44 592499.0 158000.0 0.34 0.5493 0.9927 1732933 ChemDiv1_028624 CC1CCc2c(C#N)c(NC(=O)c3c(C)onc3c4ccccc4Cl)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F03 compound treatment 722984.0 259000.0 0.53 617699.0 183000.0 0.4 0.6573 0.9892 1983335 ChemDiv1_028625 Clc1ccc(C2CC(=Nc3ccccc3S2)c4cccs4)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F04 compound treatment 698575.0 234000.0 0.48 624381.0 190000.0 0.41 0.6319 0.9967 1983336 ChemDiv1_028626 Fc1ccc(cc1)C2OC3(C4C2C(=O)N(C4=O)c5ccccc5C(F)(F)F)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F05 compound treatment 718426.0 254000.0 0.52 663765.0 229000.0 0.5 0.7211 0.9996 1983337 ChemDiv1_028627 CCN(CC)CCC(=O)N1c2ccccc2Sc3ccc(cc13)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F06 compound treatment 717629.0 253000.0 0.52 625879.0 191000.0 0.41 0.662 0.9933 1336069 ChemDiv1_028628 COc1ccc(cc1)n2c(SCc3ccccc3)nc4nc5CC(C)(C)OCc5cc4c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F07 compound treatment 745479.0 281000.0 0.58 620124.0 185000.0 0.4 0.6938 0.9837 1395774 ChemDiv1_028629 Brc1ccc2oc3C(=NCC(=O)Nc3c2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F08 compound treatment 724553.0 260000.0 0.54 649667.0 215000.0 0.46 0.7085 0.9974 1148848 ChemDiv1_028630 CCOc1ccccc1N2COc3ccc4c(C)cc(=O)oc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F09 compound treatment 744915.0 280000.0 0.58 667737.0 233000.0 0.5 0.7659 0.9976 1864646 ChemDiv1_028631 Cc1ccc(c(C)c1)S(=O)(=O)Nc2cc3c4CC(CCc4oc3c5ccccc25)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F10 compound treatment 733959.0 270000.0 0.56 661772.0 227000.0 0.49 0.7407 0.9981 1599109 ChemDiv1_028632 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(C)cc3)nc2c4ccc(OC)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F11 compound treatment 746009.0 282000.0 0.58 718837.0 284000.0 0.61 0.8457 0.9996 1346258 ChemDiv1_028633 CN1c2ccc(C)c(C)c2C(C)(C)C31Oc4ccc5ncccc5c4N=C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F12 compound treatment 723699.0 259000.0 0.54 658822.0 224000.0 0.48 0.7212 0.9988 1609622 ChemDiv1_028634 CCn1cnc2sc(C(=O)N3CCC4(CC3)OCCO4)c(C)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F13 compound treatment 741636.0 277000.0 0.57 687611.0 253000.0 0.55 0.7915 0.9997 1477575 ChemDiv1_028635 CSc1ccc(cc1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F14 compound treatment 742503.0 278000.0 0.57 655587.0 221000.0 0.48 0.7437 0.9958 1580061 ChemDiv1_028636 Nc1c(Cl)cc(cc1Cl)C(=O)NC2CCS(=O)(=O)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F15 compound treatment 759950.0 296000.0 0.61 662399.0 228000.0 0.49 0.7796 0.9944 1465080 ChemDiv1_028637 COc1ccc(C2CC(=O)Nc3c2cc(Br)c4ccccc34)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F16 compound treatment 756963.0 293000.0 0.6 666893.0 232000.0 0.5 0.7822 0.9958 1983338 ChemDiv1_028638 COC(=O)[C@]1(C[C@H](CN2CCC3(CC2)N(CNC3=O)c4ccccc4)Oc5ccc(OC)cc51)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F17 compound treatment 757326.0 293000.0 0.6 695249.0 260000.0 0.56 0.8261 0.9994 1983339 ChemDiv1_028639 COc1cccc(c1)N2C(C(N3C(=O)c4ccc(cc4C3=O)[N+](=O)[O-])C2=O)c5cccc(F)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F18 compound treatment 713517.0 249000.0 0.51 668130.0 233000.0 0.5 0.7206 1.0 1508751 ChemDiv1_028640 CN1CCN(CC2(CCCOc3ccccc32)c4ccccc4)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F19 compound treatment 751675.0 287000.0 0.59 655194.0 220000.0 0.48 0.7565 0.9942 1662851 ChemDiv1_028641 Cc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccc(F)cc3)c4ccccn4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F20 compound treatment 746563.0 282000.0 0.58 672241.0 237000.0 0.51 0.7752 0.998 1350731 ChemDiv1_028642 Cc1cccc(NC(=O)Nc2sc3CCCCc3c2c4nc5ccccc5s4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F21 compound treatment 742160.0 278000.0 0.57 684649.0 250000.0 0.54 0.7877 0.9996 1983340 ChemDiv1_028643 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F22 compound treatment 713865.0 249000.0 0.51 629200.0 194000.0 0.42 0.6616 0.995 1280664 ChemDiv1_028644 Clc1cccc(NC(=O)N2C[C@H]3C[C@@H](C2)c4cccc(=O)n4C3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F23 mock treatment 690257.0 226000.0 0.47 646478.0 212000.0 0.46 0.6535 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 F24 mock treatment 247518.0 -217000.0 -0.45 260817.0 -174000.0 -0.38 -0.583 -0.9963 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G01 compound treatment 658548.0 194000.0 0.4 544885.0 110000.0 0.24 0.4518 0.9691 1662362 ChemDiv1_028645 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2c(C)cc(C)cc2C)C#N)c3ccccc3OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G02 compound treatment 679038.0 215000.0 0.44 566408.0 132000.0 0.28 0.5146 0.9772 1552026 ChemDiv1_028646 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)Nc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G03 compound treatment 747199.0 283000.0 0.58 620511.0 186000.0 0.4 0.6969 0.9834 1197117 ChemDiv1_028647 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G04 compound treatment 694168.0 230000.0 0.47 630121.0 195000.0 0.42 0.6342 0.9983 1433242 ChemDiv1_028648 CCOC(=O)CSc1nc2CCCCc2c(c3ccc(C)o3)c1C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G05 compound treatment 745007.0 281000.0 0.58 644926.0 210000.0 0.45 0.7311 0.9928 1570236 ChemDiv1_028649 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(Cl)c2)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G06 compound treatment 753783.0 289000.0 0.6 656036.0 221000.0 0.48 0.7609 0.994 1573950 ChemDiv1_028650 Cc1cccc(NC(=O)c2sc3nc4CCCCc4c(c5ccco5)c3c2N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G07 compound treatment 694883.0 230000.0 0.48 606626.0 172000.0 0.37 0.5993 0.9926 1489074 ChemDiv1_028651 CCOc1ccc(cc1)C2C(C(=O)OC)C(=O)NC(=C2C#N)SCc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G08 compound treatment 809071.0 345000.0 0.71 667747.0 233000.0 0.5 0.8595 0.9858 1622519 ChemDiv1_028652 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(F)cc4)c(N)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G09 compound treatment 744272.0 280000.0 0.58 607955.0 173000.0 0.37 0.6734 0.978 1296148 ChemDiv1_028653 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4cccc(Cl)c4)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G10 compound treatment 729019.0 265000.0 0.55 621658.0 187000.0 0.4 0.6721 0.989 1932364 ChemDiv1_028654 CN1C(=O)C2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G11 compound treatment 775878.0 311000.0 0.64 632786.0 198000.0 0.43 0.7576 0.9805 1152603 ChemDiv1_028655 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cc(OC)c(Cl)cc2OC)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G12 compound treatment 853733.0 389000.0 0.8 734378.0 300000.0 0.65 1.0267 0.9943 1983341 ChemDiv1_028656 Cc1ccc(cc1)N2C(=O)/C(=C\c3ccc(o3)c4ccccc4C(=O)O)/C(=O)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G13 compound treatment 779154.0 315000.0 0.65 674486.0 240000.0 0.52 0.8262 0.9938 1983342 ChemDiv1_028657 CCOc1ccccc1C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccc(cc4)C(=O)C)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G14 compound treatment 742611.0 278000.0 0.57 640344.0 205000.0 0.44 0.7206 0.992 1983343 ChemDiv1_028658 CCOc1cccc(c1)N2C(=O)NC(=O)/C(=C/c3ccc(Oc4ccc(cn4)[N+](=O)[O-])cc3)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G15 compound treatment 787188.0 323000.0 0.67 696931.0 262000.0 0.57 0.8722 0.9968 1137160 ChemDiv1_028659 Nc1c(sc2nc3CCCCc3c(c4ccco4)c12)C(=O)Nc5ccc(Cl)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G16 compound treatment 735716.0 271000.0 0.56 635356.0 201000.0 0.43 0.7029 0.9921 1983344 ChemDiv1_028660 COc1ccc(Oc2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G17 compound treatment 774216.0 310000.0 0.64 687926.0 253000.0 0.55 0.8395 0.997 1983345 ChemDiv1_028661 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G18 compound treatment 752912.0 288000.0 0.6 642620.0 208000.0 0.45 0.7391 0.9904 1983346 ChemDiv1_028662 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)c4ccncc4)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G19 compound treatment 776827.0 312000.0 0.64 664981.0 230000.0 0.5 0.8082 0.9919 1222991 ChemDiv1_028663 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G20 compound treatment 754531.0 290000.0 0.6 667631.0 233000.0 0.5 0.7797 0.9963 1118306 ChemDiv1_028664 COc1ccccc1C(=O)Oc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G21 compound treatment 776071.0 312000.0 0.64 645945.0 211000.0 0.46 0.778 0.9859 1368238 ChemDiv1_028665 Nc1c(sc2nc3CCCC(=O)c3cc12)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G22 compound treatment 727743.0 263000.0 0.54 632180.0 197000.0 0.43 0.6864 0.9929 1307086 ChemDiv1_028666 COc1ccc(Oc2coc3cc(OC(=O)c4c(OC)cccc4OC)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G23 mock treatment 713380.0 249000.0 0.51 618772.0 184000.0 0.4 0.6449 0.992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 G24 mock treatment 233246.0 -231000.0 -0.48 241309.0 -194000.0 -0.42 -0.6336 -0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H01 compound treatment 626688.0 162000.0 0.33 541306.0 106000.0 0.23 0.3998 0.9833 1743388 ChemDiv1_028667 Cn1c(=O)n(C)c2nc(Cl)n(CC(=O)c3ccc(Br)cc3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H02 compound treatment 671987.0 208000.0 0.43 564559.0 130000.0 0.28 0.5015 0.979 1983347 ChemDiv1_028668 CC1(C)C2(CN3CC1(CN(C2)C3c4cc(Br)ccc4O)[N+](=O)[O-])[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H03 compound treatment 704856.0 240000.0 0.5 641992.0 207000.0 0.45 0.668 0.9987 1672535 ChemDiv1_028669 Clc1ccc(cc1)N2OC3C(C2c4cccs4)C(=O)N(Cc5ccccc5)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H04 compound treatment 693595.0 229000.0 0.47 611728.0 177000.0 0.38 0.6052 0.9945 1229303 ChemDiv1_028670 CC1(C)CC(=O)c2cc(C(=O)NCCc3ccccc3)c(=O)n(c4ccccc4)c2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H05 compound treatment 689605.0 225000.0 0.46 634291.0 199000.0 0.43 0.6339 0.9993 1631783 ChemDiv1_028671 COc1ccccc1CC(=O)N2CCCc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H06 compound treatment 687684.0 223000.0 0.46 605081.0 170000.0 0.37 0.5864 0.9938 1571419 ChemDiv1_028672 CSc1nc2nc3CC(C)(C)OCc3cc2c(=O)n1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H07 compound treatment 726839.0 262000.0 0.54 648633.0 214000.0 0.46 0.7102 0.9969 1928011 ChemDiv1_028673 COC(=O)C(CC(C)C)NC(=O)CSc1nnc2c3ccccc3[nH]c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H08 compound treatment 706109.0 242000.0 0.5 622143.0 187000.0 0.41 0.6394 0.9947 1983348 ChemDiv1_028674 CC1CCN(CC(=O)N2c3ccccc3Sc4ccccc24)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H09 compound treatment 712432.0 248000.0 0.51 654271.0 219000.0 0.47 0.6978 0.9993 1324587 ChemDiv1_028675 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H10 compound treatment 699579.0 235000.0 0.49 623780.0 189000.0 0.41 0.6324 0.9964 1135057 ChemDiv1_028676 COc1ccc(cc1)c2nnc(SCC(=O)NC(C)(C)C)nc2c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H11 compound treatment 1259534.0 795000.0 1.64 1177213.0 742000.0 1.61 2.2968 0.9999 1111260 ChemDiv1_028677 Nc1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H12 compound treatment 686437.0 222000.0 0.46 597739.0 163000.0 0.35 0.5734 0.9916 1708663 ChemDiv1_028678 CCC(CO)NCC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H13 compound treatment 705877.0 241000.0 0.5 655510.0 221000.0 0.48 0.6902 0.9998 1232497 ChemDiv1_028679 CC(=O)Nc1ccc(cc1)N(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H14 compound treatment 713196.0 249000.0 0.51 617071.0 182000.0 0.39 0.642 0.9915 1983349 ChemDiv1_028680 CC(C)(C)c1ccc(OS(=O)(=O)O)c(CN2CCCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H15 compound treatment 761617.0 297000.0 0.61 681627.0 247000.0 0.53 0.8115 0.9976 1983350 ChemDiv1_028681 CCCCCCCCOc1ccc(cc1)C2Nc3cc(C)ccc3C(=O)CS2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H16 compound treatment 726341.0 262000.0 0.54 628840.0 194000.0 0.42 0.6792 0.9922 1983351 ChemDiv1_028682 CCOC(=O)C(C(Sc1ccccc1)C(C)(C)C2OCCO2)(N3C(=O)c4ccccc4C3=O)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H17 compound treatment 755299.0 291000.0 0.6 665670.0 231000.0 0.5 0.7779 0.9958 1737671 ChemDiv1_028683 Cc1cccc(c1)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H18 compound treatment 682548.0 218000.0 0.45 635754.0 201000.0 0.43 0.6259 0.9998 1355507 ChemDiv1_028684 CC(C)COCC1CC2(CC(C)(OC2=O)c3csc(NCC=C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H19 compound treatment 721995.0 258000.0 0.53 677303.0 242000.0 0.52 0.747 1.0 1196950 ChemDiv1_028685 Oc1ccc(Br)cc1c2nc3c([nH]2)c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H20 compound treatment 718714.0 254000.0 0.52 638513.0 204000.0 0.44 0.6829 0.9962 1391287 ChemDiv1_028686 CCn1nc(CC(=O)c2ccc(Br)cc2)c(=O)n3c4ccccc4nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H21 compound treatment 703669.0 239000.0 0.49 664149.0 229000.0 0.5 0.7002 1.0 1983352 ChemDiv1_028687 COC(=O)C1=NNC2C1C(=O)N(C2=O)c3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H22 compound treatment 734976.0 271000.0 0.56 679410.0 245000.0 0.53 0.7692 0.9996 1983353 ChemDiv1_028688 O=C(Nc1nc(cn1/N=C/c2ccccc2)c3ccco3)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H23 mock treatment 691835.0 227000.0 0.47 622557.0 188000.0 0.41 0.6192 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 H24 mock treatment 255330.0 -209000.0 -0.43 210229.0 -225000.0 -0.49 -0.649 -0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I01 compound treatment 667714.0 203000.0 0.42 567236.0 132000.0 0.29 0.4994 0.9827 1700381 ChemDiv1_028689 CCOC(=O)c1sc2nc(cc(c3ccco3)c2c1N)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I02 compound treatment 692713.0 228000.0 0.47 559683.0 125000.0 0.27 0.5243 0.9651 1537165 ChemDiv1_028690 CCOc1ccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I03 compound treatment 727662.0 263000.0 0.54 593490.0 159000.0 0.34 0.627 0.9755 1187370 ChemDiv1_028691 COc1ccc(cc1)C2C(=C(NC3=C2C(=O)CC(C)(C)C3)SCC(=O)Nc4ccccc4C)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I04 compound treatment 716547.0 252000.0 0.52 611926.0 177000.0 0.38 0.639 0.9887 1197477 ChemDiv1_028692 Cc1ccccc1NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I05 compound treatment 738689.0 274000.0 0.57 603443.0 169000.0 0.36 0.6584 0.9774 1518217 ChemDiv1_028693 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3cccc(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I06 compound treatment 724378.0 260000.0 0.54 604626.0 170000.0 0.37 0.6393 0.9829 1539790 ChemDiv1_028694 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I07 compound treatment 735542.0 271000.0 0.56 635444.0 201000.0 0.43 0.7028 0.9921 1739802 ChemDiv1_028695 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2c(C)cccc2C)C#N)c3ccccc3OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I08 compound treatment 734445.0 270000.0 0.56 630916.0 196000.0 0.42 0.6942 0.9909 1563995 ChemDiv1_028696 CC1=C(C(C(=C(N1)SCC(=O)Nc2c(C)cc(C)cc2C)C#N)c3cccs3)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I09 compound treatment 769193.0 305000.0 0.63 657430.0 223000.0 0.48 0.7855 0.9913 1983354 ChemDiv1_028697 COc1ccc(cc1OC)c2c(C#N)c(SCC(=O)Nc3ccccc3)nc(C)c2C(=O)Nc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I10 compound treatment 737194.0 273000.0 0.56 617387.0 183000.0 0.4 0.6775 0.985 1983355 ChemDiv1_028698 Brc1ccc2NC(=O)/C(=C\c3nc4ccccc4c(=O)n3c5ccccc5)/c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I11 compound treatment 759172.0 295000.0 0.61 638331.0 203000.0 0.44 0.7417 0.9874 1636928 ChemDiv1_028699 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccccc4)c(N)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I12 compound treatment 723575.0 259000.0 0.53 628635.0 194000.0 0.42 0.6749 0.9927 1983356 ChemDiv1_028700 CCOC(=O)COc1ccc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I13 compound treatment 755684.0 291000.0 0.6 658920.0 224000.0 0.48 0.7681 0.9943 1391516 ChemDiv1_028701 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)c(C)c2)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I14 compound treatment 740190.0 276000.0 0.57 644892.0 210000.0 0.45 0.724 0.9938 1983357 ChemDiv1_028702 [O-][N+](=O)c1ccc(Oc2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4F)cc2)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I15 compound treatment 766486.0 302000.0 0.62 653645.0 219000.0 0.47 0.7758 0.9908 1533624 ChemDiv1_028703 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2CC)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I16 compound treatment 752759.0 288000.0 0.6 649965.0 215000.0 0.47 0.7501 0.9926 1983358 ChemDiv1_028704 COc1ccc(Oc2c(oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I17 compound treatment 775984.0 312000.0 0.64 667609.0 233000.0 0.5 0.811 0.9927 1547334 ChemDiv1_028705 CCOc1ccccc1C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4cccc(C)c4)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I18 compound treatment 733424.0 269000.0 0.56 643263.0 208000.0 0.45 0.7116 0.9947 1983359 ChemDiv1_028706 FC(F)(F)c1oc2cc(OC(=O)c3ccco3)ccc2c(=O)c1c4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I19 compound treatment 768666.0 304000.0 0.63 659042.0 224000.0 0.49 0.7872 0.9919 1983360 ChemDiv1_028707 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I20 compound treatment 729240.0 265000.0 0.55 650193.0 215000.0 0.47 0.7161 0.9968 1586750 ChemDiv1_028708 COc1ccc(cc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I21 compound treatment 766425.0 302000.0 0.62 642047.0 207000.0 0.45 0.7579 0.9869 1293076 ChemDiv1_028709 CCc1ccc(NC(=O)c2sc3nc(N)c(C#N)c(c4ccc(OC)c(OC)c4)c3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I22 compound treatment 736862.0 272000.0 0.56 614462.0 180000.0 0.39 0.6726 0.9837 1983361 ChemDiv1_028710 COc1ccc(Oc2coc3cc(OC(=O)c4cc(OC)c(OC)c(OC)c4)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I23 mock treatment 721265.0 257000.0 0.53 617315.0 182000.0 0.39 0.6542 0.9895 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 I24 mock treatment 224303.0 -240000.0 -0.5 215664.0 -219000.0 -0.47 -0.6859 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J01 compound treatment 626582.0 162000.0 0.33 560829.0 126000.0 0.27 0.4295 0.9948 1635005 ChemDiv1_028711 Clc1ccccc1C2=Nc3ccccc3NC(=O)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J02 compound treatment 667267.0 203000.0 0.42 584114.0 149000.0 0.32 0.5245 0.9918 1681928 ChemDiv1_028712 CC1CC2(CC(C)(OC2=O)c3csc(N)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J03 compound treatment 772821.0 308000.0 0.64 677655.0 243000.0 0.53 0.8218 0.9955 1983362 ChemDiv1_028713 COc1ccc(cc1OC)C2=N/C(=C/c3ccccc3OC)/C(=O)N2c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J04 compound treatment 679061.0 215000.0 0.44 650298.0 215000.0 0.47 0.643 0.9997 1576309 ChemDiv1_028714 CC(=O)N1c2ccc(C)cc2-c3ccccc3S1(=O)=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J05 compound treatment 756086.0 292000.0 0.6 661241.0 226000.0 0.49 0.7722 0.9948 1983363 ChemDiv1_028715 CC(=O)C1=C(C)NC(=C(C#N)C1c2sccc2C)SCC(=O)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J06 compound treatment 710643.0 246000.0 0.51 621970.0 187000.0 0.4 0.6458 0.9937 1300669 ChemDiv1_028716 CC1(C)Cc2nc3nc(SCC=C)n(c4ccccc4)c(=O)c3cc2CO1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J07 compound treatment 740520.0 276000.0 0.57 686221.0 251000.0 0.54 0.7877 0.9997 1983364 ChemDiv1_028717 CC(=O)c1c(C)n(c2ccc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc12)S(=O)(=O)c4ccc(cc4)C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J08 compound treatment 715825.0 251000.0 0.52 635197.0 200000.0 0.43 0.6736 0.996 1651263 ChemDiv1_028718 CCN(CC)c1ncnc2c1sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J09 compound treatment 762544.0 298000.0 0.62 640046.0 205000.0 0.44 0.7492 0.9872 1983365 ChemDiv1_028719 FC(F)(F)c1ccc(cc1)C(CC(=O)c2cccs2)SCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J10 compound treatment 699558.0 235000.0 0.49 625412.0 191000.0 0.41 0.6349 0.9967 1529157 ChemDiv1_028720 Cc1nc2oc(C(=O)c3ccc(Br)cc3)c(N)c2c4CC(C)(C)OCc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J11 compound treatment 707860.0 243000.0 0.5 660820.0 226000.0 0.49 0.7012 0.9999 1983366 ChemDiv1_028721 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CSC4=NCCS4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J12 compound treatment 706662.0 242000.0 0.5 639843.0 205000.0 0.44 0.6673 0.9982 1245457 ChemDiv1_028722 Cc1cc(=O)oc2c3CN(COc3ccc12)c4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J13 compound treatment 740298.0 276000.0 0.57 598651.0 164000.0 0.35 0.6534 0.974 1511247 ChemDiv1_028723 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J14 compound treatment 714146.0 250000.0 0.52 655225.0 220000.0 0.48 0.7018 0.9992 1672568 ChemDiv1_028724 CNCC1OC(Cc2c(O)c(O)ccc12)C3(CC4CC5CC(C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J15 compound treatment 740185.0 276000.0 0.57 682586.0 248000.0 0.54 0.7817 0.9996 1983367 ChemDiv1_028725 Clc1c2C(=O)N(C3C(N(C3=O)c4ccc(Br)cc4)c5cccs5)C(=O)c2c(Cl)c(Cl)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J16 compound treatment 719256.0 255000.0 0.53 699908.0 265000.0 0.57 0.7776 0.9991 1983368 ChemDiv1_028726 Clc1ccc(cc1)C2NC(=O)c3ccccc3S2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J17 compound treatment 745145.0 281000.0 0.58 656232.0 221000.0 0.48 0.7486 0.9955 1983369 ChemDiv1_028727 COc1ccc(cc1)N2C(=O)CC(C3=C2CCCC3=O)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J18 compound treatment 716048.0 252000.0 0.52 669940.0 235000.0 0.51 0.7271 0.9999 1983370 ChemDiv1_028728 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J19 compound treatment 744938.0 281000.0 0.58 657565.0 223000.0 0.48 0.7503 0.9958 1660058 ChemDiv1_028729 Oc1c(Br)cc2oc3CCCCc3c2c1CNc4ccccc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J20 compound treatment 725478.0 261000.0 0.54 654394.0 220000.0 0.48 0.7171 0.998 1350555 ChemDiv1_028730 CC(C)C1(CC2C(CC1)C(=O)O)OC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J21 compound treatment 729548.0 265000.0 0.55 675184.0 240000.0 0.52 0.7548 0.9997 1534721 ChemDiv1_028731 CN1c2ccccc2C(C)(C)C31Oc4c(cc5ccccc5c4N=C3)C(=O)N6CCOCC6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J22 compound treatment 715872.0 251000.0 0.52 645012.0 210000.0 0.45 0.6887 0.9978 1983371 ChemDiv1_028732 Cc1cc(C)c-2c(CC(C)(C)c3nc4c(cccc4nc32)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J23 mock treatment 694863.0 230000.0 0.48 647809.0 213000.0 0.46 0.6623 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 J24 mock treatment 207360.0 -257000.0 -0.53 234575.0 -200000.0 -0.43 -0.6817 -0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K01 compound treatment 664482.0 200000.0 0.41 544747.0 110000.0 0.24 0.4602 0.9656 1310680 ChemDiv1_028733 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2nccs2)C#N)c3ccccc3OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K02 compound treatment 686827.0 222000.0 0.46 553599.0 119000.0 0.26 0.5064 0.9624 1129829 ChemDiv1_028734 CC(C)c1ccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K03 compound treatment 718827.0 254000.0 0.53 599958.0 165000.0 0.36 0.624 0.9824 1276981 ChemDiv1_028735 CC1=C(C(C(=C(N1)SCC(=O)Nc2nccs2)C#N)c3ccco3)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K04 compound treatment 651233.0 187000.0 0.39 616720.0 182000.0 0.39 0.551 0.9999 1350514 ChemDiv1_028736 O=C(CSc1nc2CCCCc2c(c3ccco3)c1C#N)Nc4nccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K05 compound treatment 710978.0 247000.0 0.51 599075.0 164000.0 0.36 0.6112 0.9846 1701041 ChemDiv1_028737 CCOc1ccc(cc1)C2C(C(=O)OC)C(=O)NC(=C2C#N)SCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K06 compound treatment 698879.0 234000.0 0.48 608193.0 173000.0 0.38 0.6075 0.9921 1983372 ChemDiv1_028738 CC(=O)c1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K07 compound treatment 725043.0 261000.0 0.54 629586.0 195000.0 0.42 0.6785 0.9927 1531109 ChemDiv1_028739 CCOC(=O)C1C(C(=C(NC1=O)SCc2ccc(Cl)cc2)C#N)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K08 compound treatment 730735.0 266000.0 0.55 631353.0 197000.0 0.43 0.6895 0.992 1517187 ChemDiv1_028740 COc1cc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OCC=C)c3cccs3)c(OC)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K09 compound treatment 756779.0 292000.0 0.6 633974.0 199000.0 0.43 0.7315 0.9864 1983373 ChemDiv1_028741 CCc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(Cl)cc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K10 compound treatment 733485.0 269000.0 0.56 611929.0 177000.0 0.38 0.6638 0.9836 1983374 ChemDiv1_028742 CCN1C(=O)C2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K11 compound treatment 748104.0 284000.0 0.59 689674.0 255000.0 0.55 0.8041 0.9996 1643856 ChemDiv1_028743 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(F)cc2)C#N)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K12 compound treatment 729918.0 266000.0 0.55 622881.0 188000.0 0.41 0.6753 0.9893 1983375 ChemDiv1_028744 Clc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc4OCOc4cc3Br)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K13 compound treatment 715093.0 251000.0 0.52 659569.0 225000.0 0.49 0.7098 0.9995 1175179 ChemDiv1_028745 Clc1ccc(NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K14 compound treatment 746789.0 282000.0 0.58 634250.0 199000.0 0.43 0.7173 0.9891 1983376 ChemDiv1_028746 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(Cl)cc(Br)c3O)/C(=O)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K15 compound treatment 775835.0 311000.0 0.64 669178.0 234000.0 0.51 0.8132 0.9931 1235080 ChemDiv1_028747 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(Cl)c2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K16 compound treatment 714833.0 250000.0 0.52 589801.0 155000.0 0.34 0.6027 0.9781 1983377 ChemDiv1_028748 CCOC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K17 compound treatment 740719.0 276000.0 0.57 661985.0 227000.0 0.49 0.7509 0.9973 1318270 ChemDiv1_028749 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3c(C)cc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K18 compound treatment 731544.0 267000.0 0.55 641723.0 207000.0 0.45 0.7065 0.9947 1983378 ChemDiv1_028750 Cc1cc(C)cc(Oc2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K19 compound treatment 786545.0 322000.0 0.66 645440.0 211000.0 0.46 0.7925 0.983 1276598 ChemDiv1_028751 COc1ccc(NC(=O)c2sc3nc4CC(C)(C)CC(=O)c4cc3c2N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K20 compound treatment 745243.0 281000.0 0.58 641561.0 207000.0 0.45 0.7263 0.9918 1351175 ChemDiv1_028752 COc1ccc(cc1OC)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K21 compound treatment 754743.0 290000.0 0.6 644560.0 210000.0 0.45 0.7447 0.9906 1983379 ChemDiv1_028753 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(cc2)C(=O)C)C#N)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K22 compound treatment 731706.0 267000.0 0.55 623610.0 189000.0 0.41 0.679 0.9891 1983380 ChemDiv1_028754 COc1ccc(Oc2c(oc3cc(OC(=O)c4cccs4)ccc3c2=O)C(F)(F)F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K23 mock treatment 726341.0 262000.0 0.54 608991.0 174000.0 0.38 0.6488 0.9844 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 K24 mock treatment 197370.0 -267000.0 -0.55 236460.0 -198000.0 -0.43 -0.6934 -0.9924 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L01 compound treatment 732027.0 268000.0 0.55 653680.0 219000.0 0.47 0.7255 0.9971 1983381 ChemDiv1_028755 COc1ccc(cc1)C(=O)C2C(c3cccnc3)C(C#N)(C#N)C4N2C=Cc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L02 compound treatment 664629.0 200000.0 0.41 591188.0 156000.0 0.34 0.5315 0.9951 1725430 ChemDiv1_028756 CC1CC2(CC(C)(OC2=O)c3csc(Nc4ccccc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L03 compound treatment 695940.0 232000.0 0.48 637728.0 203000.0 0.44 0.6484 0.9991 1776505 ChemDiv1_028757 CCOC(=O)/C(=C\1/NC(C)(C)Cc2ccccc12)/C(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L04 compound treatment 695755.0 231000.0 0.48 613248.0 178000.0 0.39 0.6107 0.9944 1675199 ChemDiv1_028758 Cc1ccc2N(C(=O)c3ccccc3)S(=O)(=O)c4ccccc4-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L05 compound treatment 701633.0 237000.0 0.49 626549.0 192000.0 0.41 0.6396 0.9966 1983382 ChemDiv1_028759 COc1cc(cc(Br)c1O)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C5)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L06 compound treatment 700894.0 236000.0 0.49 617455.0 183000.0 0.4 0.6247 0.9945 1513753 ChemDiv1_028760 CCOC(=O)c1c(NC(=S)Nc2ccc(OC)cc2)sc3COC(C)(C)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L07 compound treatment 711917.0 248000.0 0.51 648903.0 214000.0 0.46 0.6889 0.9988 1429865 ChemDiv1_028761 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L08 compound treatment 698444.0 234000.0 0.48 629123.0 194000.0 0.42 0.6389 0.9976 1156443 ChemDiv1_028762 Cc1nc2CC(C)(C)CC(O)c2c3c4ccccc4[nH]c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L09 compound treatment 722372.0 258000.0 0.53 670871.0 236000.0 0.51 0.7378 0.9998 1306397 ChemDiv1_028763 CCc1nc2c(sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c32)c(=O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L10 compound treatment 718527.0 254000.0 0.52 625271.0 190000.0 0.41 0.6624 0.9929 1270117 ChemDiv1_028764 CCOC(=O)c1oc2nc(C)c3COC(C)(C)Cc3c2c1N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L11 compound treatment 733541.0 269000.0 0.56 649248.0 214000.0 0.46 0.721 0.996 1943991 ChemDiv1_028765 CN1CCN(CC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L12 compound treatment 730619.0 266000.0 0.55 648092.0 213000.0 0.46 0.7149 0.9962 1139255 ChemDiv1_028766 CC(C)(C)c1ccc(cc1)C(=O)N(CCc2ccccc2)C3CCS(=O)(=O)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L13 compound treatment 719561.0 255000.0 0.53 649344.0 214000.0 0.46 0.7007 0.998 1783649 ChemDiv1_028767 Cc1ccc(cc1)N(CC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)S(=O)(=O)c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L14 compound treatment 705206.0 241000.0 0.5 656397.0 222000.0 0.48 0.6905 0.9998 1983383 ChemDiv1_028768 CC(NC(=O)C(CC(=O)N)NC(=O)OC(C)(C)C)C(=O)NC1CCN(C1)c2nc3n(cc(C(=O)O)c(=O)c3cc2F)c4ccc(F)cc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L15 compound treatment 728358.0 264000.0 0.54 671936.0 237000.0 0.51 0.7481 0.9996 1983384 ChemDiv1_028769 [O-][N+](=O)c1cc(Cl)ccc1N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L16 compound treatment 692142.0 228000.0 0.47 656875.0 222000.0 0.48 0.6722 0.9999 1651764 ChemDiv1_028770 CC(C)(C)c1ccc(O)c(CN2CCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L17 compound treatment 762255.0 298000.0 0.61 688469.0 254000.0 0.55 0.8229 0.9984 1931043 ChemDiv1_028771 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccccc3OC)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L18 compound treatment 708785.0 244000.0 0.5 637598.0 203000.0 0.44 0.667 0.9976 1128895 ChemDiv1_028772 Brc1ccc(cc1)c2csc(n2)C(=C3CCCCC3)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L19 compound treatment 706560.0 242000.0 0.5 629430.0 195000.0 0.42 0.6512 0.9964 1177827 ChemDiv1_028773 Fc1cccc(c1)C2Nc3cccc4cccc(N2)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L20 compound treatment 702895.0 238000.0 0.49 677735.0 243000.0 0.53 0.7198 0.9995 1983385 ChemDiv1_028774 Cc1ccc(Cl)cc1NC(=O)/C(=C/c2ccc3OCOc3c2)/NC(=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L21 compound treatment 752080.0 288000.0 0.59 690652.0 256000.0 0.55 0.8114 0.9994 1983386 ChemDiv1_028775 [O-][N+](=O)c1ccc(/C=C/2\N3C(=NC2=O)N(CCN4CCOCC4)c5ccccc35)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L22 compound treatment 741836.0 277000.0 0.57 729581.0 295000.0 0.64 0.856 0.9986 1983387 ChemDiv1_028776 Cc1cc2N=C(CC(=Nc2cc1C)C(F)(F)F)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L23 mock treatment 692461.0 228000.0 0.47 622753.0 188000.0 0.41 0.6204 0.9973 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 L24 mock treatment 210365.0 -254000.0 -0.52 216617.0 -218000.0 -0.47 -0.7048 -0.9986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M01 compound treatment 658700.0 194000.0 0.4 549483.0 115000.0 0.25 0.459 0.9733 1501219 ChemDiv1_028777 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(C)c2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M02 compound treatment 694573.0 230000.0 0.48 562381.0 128000.0 0.28 0.5311 0.9666 1427468 ChemDiv1_028778 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M03 compound treatment 715904.0 251000.0 0.52 591681.0 157000.0 0.34 0.6071 0.9788 1133037 ChemDiv1_028779 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(Cl)c2C)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M04 compound treatment 723922.0 260000.0 0.54 590299.0 155000.0 0.34 0.6167 0.9749 1725505 ChemDiv1_028780 COc1cccc(NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M05 compound treatment 740440.0 276000.0 0.57 593629.0 159000.0 0.34 0.6459 0.9707 1315440 ChemDiv1_028781 Brc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc4OCOc4c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M06 compound treatment 698065.0 234000.0 0.48 600443.0 166000.0 0.36 0.5945 0.9893 1983388 ChemDiv1_028782 CC(=O)c1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M07 compound treatment 743630.0 279000.0 0.58 626480.0 192000.0 0.41 0.7008 0.987 1386220 ChemDiv1_028783 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)c(C)c2)C#N)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M08 compound treatment 717827.0 253000.0 0.52 622211.0 187000.0 0.41 0.6566 0.9921 1545020 ChemDiv1_028784 CC1=C(C(C(=C(N1)SCC(=O)Nc2nccs2)C#N)c3cccs3)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M09 compound treatment 740173.0 276000.0 0.57 631345.0 196000.0 0.43 0.7032 0.9897 1717437 ChemDiv1_028785 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(OC)cc2)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M10 compound treatment 728887.0 264000.0 0.55 604941.0 170000.0 0.37 0.6464 0.9816 1983389 ChemDiv1_028786 COC(=O)COc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(cc3)C(C)(C)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M11 compound treatment 744967.0 281000.0 0.58 616153.0 181000.0 0.39 0.687 0.982 1740786 ChemDiv1_028787 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)c(C)c2)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M12 compound treatment 714838.0 250000.0 0.52 590537.0 156000.0 0.34 0.6038 0.9785 1983390 ChemDiv1_028788 CN1C(=O)S/C(=C\c2cc(C)n(c2C)c3ccc(Br)cc3F)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M13 compound treatment 757980.0 294000.0 0.61 632272.0 197000.0 0.43 0.7307 0.9854 1351027 ChemDiv1_028789 Fc1cccc(NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M14 compound treatment 846320.0 382000.0 0.79 758946.0 324000.0 0.7 1.0535 0.9983 1983391 ChemDiv1_028790 OC(=O)c1ccc(Cl)c(c1)c2ccc(/C=C\3/C(=O)NC(=S)N(CC=C)C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M15 compound treatment 764743.0 300000.0 0.62 657274.0 222000.0 0.48 0.7788 0.9922 1642644 ChemDiv1_028791 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(F)c2)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M16 compound treatment 716430.0 252000.0 0.52 618035.0 183000.0 0.4 0.6482 0.991 1941406 ChemDiv1_028792 Oc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1CN4CCCC4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M17 compound treatment 745053.0 281000.0 0.58 631226.0 196000.0 0.43 0.7102 0.9884 1127220 ChemDiv1_028793 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M18 compound treatment 734299.0 270000.0 0.56 631399.0 197000.0 0.43 0.6948 0.9911 1983392 ChemDiv1_028794 CN1CCN(Cc2c(O)ccc3c(=O)c(Oc4cc(C)cc(C)c4)c(oc23)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M19 compound treatment 766548.0 302000.0 0.62 664661.0 230000.0 0.5 0.7927 0.9937 1367282 ChemDiv1_028795 Cc1ccc(Cl)cc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M20 compound treatment 746009.0 282000.0 0.58 633812.0 199000.0 0.43 0.7155 0.9891 1663361 ChemDiv1_028796 COc1cccc(OC)c1C(=O)Oc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M21 compound treatment 724689.0 260000.0 0.54 641450.0 207000.0 0.45 0.6961 0.9958 1234701 ChemDiv1_028797 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4cccc(C)c4C)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M22 compound treatment 727447.0 263000.0 0.54 613217.0 178000.0 0.39 0.6569 0.986 1983393 ChemDiv1_028798 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3cc(OC)c(OC)cc3OC)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M23 mock treatment 704856.0 240000.0 0.5 626798.0 192000.0 0.42 0.6447 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 M24 mock treatment 395075.0 -69300.0 -0.14 351209.0 -83600.0 -0.18 -0.2292 -0.9932 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N01 compound treatment 651329.0 187000.0 0.39 573524.0 139000.0 0.3 0.4851 0.9923 1983394 ChemDiv1_028799 COc1ccc(cc1)c2cc(nc3sc4c(O)cc(=O)[nH]c4c23)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N02 compound treatment 679937.0 216000.0 0.44 578738.0 144000.0 0.31 0.5348 0.9848 1334677 ChemDiv1_028800 CC1(C)CC2(CC(C)(OC2=O)c3csc(NCC=C)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N03 compound treatment 704804.0 240000.0 0.5 599105.0 164000.0 0.36 0.6023 0.9866 1983395 ChemDiv1_028801 COc1ccccc1C(O)(C(=O)N(NC(=O)C)c2ccccc2)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N04 compound treatment 696599.0 232000.0 0.48 594653.0 160000.0 0.35 0.5835 0.9872 1225214 ChemDiv1_028802 Cc1ccc(C)c-2c1NS(=O)(=O)c3ccccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N05 compound treatment 721233.0 257000.0 0.53 628549.0 194000.0 0.42 0.6713 0.9932 1983396 ChemDiv1_028803 Cc1cc(C)c(C2=NON3N(C(=O)C4(CC5CC6CC(C5)C4)C6)c7ccccc7N32)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N06 compound treatment 710277.0 246000.0 0.51 619499.0 185000.0 0.4 0.6415 0.993 1537090 ChemDiv1_028804 CCOC(=O)c1c(NC(=S)NC2CCCCC2)sc3COC(C)(C)Cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N07 compound treatment 711586.0 247000.0 0.51 638834.0 204000.0 0.44 0.673 0.9974 1233654 ChemDiv1_028805 CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CC(C)(C)CC(=O)c4c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N08 compound treatment 692133.0 228000.0 0.47 630364.0 196000.0 0.42 0.6316 0.9986 1983397 ChemDiv1_028806 COc1ccc(c(C)c1)S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N09 compound treatment 704162.0 240000.0 0.49 638669.0 204000.0 0.44 0.6619 0.9984 1669885 ChemDiv1_028807 CCN(CC)CCC(=O)N1c2ccccc2CCc3ccc(NC(=O)C(C)C)cc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N10 compound treatment 693365.0 229000.0 0.47 623441.0 189000.0 0.41 0.6228 0.9973 1636837 ChemDiv1_028808 COc1cc(cc(OC)c1O)C2CC(=O)Nc3ccc4ccccc4c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N11 compound treatment 746569.0 282000.0 0.58 643855.0 209000.0 0.45 0.7317 0.9922 1332446 ChemDiv1_028809 CCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N12 compound treatment 693008.0 229000.0 0.47 616188.0 181000.0 0.39 0.6112 0.9958 1692986 ChemDiv1_028810 CCC(=O)Nc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N13 compound treatment 712896.0 248000.0 0.51 625088.0 190000.0 0.41 0.6539 0.9941 1525085 ChemDiv1_028811 Cc1ccc(cc1)N(CC(O)CN2CCCCC2)S(=O)(=O)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N14 compound treatment 723922.0 260000.0 0.54 650903.0 216000.0 0.47 0.7095 0.9977 1983398 ChemDiv1_028812 Cc1nn(c(O)c1C(c2c(C)nn(c2O)c3ccccc3)c4ccc(Cl)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N15 compound treatment 733290.0 269000.0 0.56 643349.0 208000.0 0.45 0.7116 0.9947 1983399 ChemDiv1_028813 COc1ccc(cc1Cl)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N16 compound treatment 675681.0 211000.0 0.44 633001.0 198000.0 0.43 0.6116 1.0 1397153 ChemDiv1_028814 CC(C)(C)c1cc(Cl)c(O)c(CN2CCCCC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N17 compound treatment 714542.0 250000.0 0.52 666161.0 231000.0 0.5 0.7191 0.9999 1357544 ChemDiv1_028815 CCCCn1c(=O)nc2n(c3ccc(OCC)cc3)c4ccccc4cc2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N18 compound treatment 712180.0 248000.0 0.51 646976.0 212000.0 0.46 0.6863 0.9985 1225110 ChemDiv1_028816 O=C(N1CCOCC1)N2c3ccccc3CC(N4CCOCC4)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N19 compound treatment 722935.0 259000.0 0.53 651382.0 217000.0 0.47 0.7087 0.9979 1950873 ChemDiv1_028817 CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N20 compound treatment 750033.0 286000.0 0.59 688999.0 254000.0 0.55 0.8059 0.9994 1588170 ChemDiv1_028818 Nc1ncnc2oc(c3ccoc3)c(c4ccco4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N21 compound treatment 736007.0 272000.0 0.56 682379.0 248000.0 0.54 0.7753 0.9997 1593432 ChemDiv1_028819 COc1ccc2c(=S)c(c(C)oc2c1)c3ccccn3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N22 compound treatment 709062.0 245000.0 0.51 625766.0 191000.0 0.41 0.6493 0.995 1214436 ChemDiv1_028820 Cc1ccc2nc(c3ccc(F)cc3)c(nc2c1)c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N23 mock treatment 695876.0 231000.0 0.48 646772.0 212000.0 0.46 0.6622 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 N24 mock treatment 373901.0 -90500.0 -0.19 441318.0 6470.0 0.01 -0.1222 -0.6523 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O01 compound treatment 630809.0 166000.0 0.34 536324.0 101000.0 0.22 0.3982 0.9767 1166044 ChemDiv1_028821 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Cl)cc2)C#N)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O02 compound treatment 668635.0 204000.0 0.42 521188.0 86300.0 0.19 0.4302 0.933 1447023 ChemDiv1_028822 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O03 compound treatment 726473.0 262000.0 0.54 564090.0 129000.0 0.28 0.5803 0.9529 1264466 ChemDiv1_028823 Cc1cccc(NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O04 compound treatment 689181.0 225000.0 0.46 575480.0 141000.0 0.3 0.5433 0.9791 1554868 ChemDiv1_028824 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccc(Br)cc4)C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O05 compound treatment 716361.0 252000.0 0.52 593593.0 159000.0 0.34 0.6107 0.9797 1120931 ChemDiv1_028825 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cc(OC)c(Cl)cc2OC)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O06 compound treatment 670191.0 206000.0 0.42 567123.0 132000.0 0.29 0.5028 0.9816 1585229 ChemDiv1_028826 COc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O07 compound treatment 711493.0 247000.0 0.51 563438.0 129000.0 0.28 0.5575 0.9594 1696062 ChemDiv1_028827 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc4OCOc4c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O08 compound treatment 704990.0 241000.0 0.5 568021.0 133000.0 0.29 0.555 0.9665 1983400 ChemDiv1_028828 CC1=C(C(C(=C(N1)SCC(=O)Nc2ccc(Br)cc2)C#N)c3cccs3)C(=O)OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O09 compound treatment 778180.0 314000.0 0.65 600249.0 165000.0 0.36 0.7111 0.9609 1713858 ChemDiv1_028829 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Cl)c(Cl)c2)C#N)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O10 compound treatment 750511.0 286000.0 0.59 604429.0 170000.0 0.37 0.6771 0.9738 1983401 ChemDiv1_028830 CCOc1cc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3C)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O11 compound treatment 724585.0 260000.0 0.54 606694.0 172000.0 0.37 0.6428 0.9839 1680488 ChemDiv1_028831 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4OCC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O12 compound treatment 701362.0 237000.0 0.49 588395.0 154000.0 0.33 0.5809 0.9823 1983402 ChemDiv1_028832 CCOc1ccc(cc1)N2C(=O)/C(=C\C3C(=NN(C3=O)c4ccccc4)C)/C(=O)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O13 compound treatment 758468.0 294000.0 0.61 603590.0 169000.0 0.37 0.6875 0.9704 1252951 ChemDiv1_028833 Cc1ccc(NC(=O)CSc2nc3CCCCc3c(c4ccco4)c2C#N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O14 compound treatment 705722.0 241000.0 0.5 620806.0 186000.0 0.4 0.6368 0.9944 1983403 ChemDiv1_028834 CCOc1ccc(cc1)N2C(=O)/C(=C\c3ccc(o3)c4ccc(cc4)[N+](=O)[O-])/C(=O)NC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O15 compound treatment 735716.0 271000.0 0.56 650062.0 215000.0 0.47 0.7254 0.9958 1983404 ChemDiv1_028835 Clc1cccc(NC(=O)CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O16 compound treatment 689566.0 225000.0 0.46 582223.0 147000.0 0.32 0.5542 0.9831 1983405 ChemDiv1_028836 CC1CN(Cc2c(O)ccc3c(=O)c(Oc4cccc(C)c4)c(oc23)C(F)(F)F)CC(C)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O17 compound treatment 734299.0 270000.0 0.56 617738.0 183000.0 0.4 0.6738 0.986 1444604 ChemDiv1_028837 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O18 compound treatment 704810.0 240000.0 0.5 595449.0 161000.0 0.35 0.5967 0.9848 1983406 ChemDiv1_028838 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4cc(C)cc(C)c4)c(oc23)C(F)(F)F)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O19 compound treatment 750657.0 286000.0 0.59 636467.0 202000.0 0.44 0.7264 0.9889 1367638 ChemDiv1_028839 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)Nc4ccc(Cl)c(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O20 compound treatment 709530.0 245000.0 0.51 586999.0 152000.0 0.33 0.5906 0.9784 1547551 ChemDiv1_028840 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4Br)coc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O21 compound treatment 747442.0 283000.0 0.58 634008.0 199000.0 0.43 0.7179 0.9888 1224307 ChemDiv1_028841 COc1ccccc1NC(=O)C2=C(C)NC(=C(C#N)C2c3ccc(C)o3)SCC(=O)Nc4nccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O22 compound treatment 703751.0 239000.0 0.49 598618.0 164000.0 0.35 0.6 0.9867 1983407 ChemDiv1_028842 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3cc(OC)c(O)c(OC)c3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O23 mock treatment 705057.0 241000.0 0.5 594730.0 160000.0 0.35 0.5959 0.9844 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 O24 mock treatment 197474.0 -267000.0 -0.55 220229.0 -215000.0 -0.46 -0.7181 -0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P01 compound treatment 608580.0 144000.0 0.3 528439.0 93600.0 0.2 0.3537 0.9824 1477818 ChemDiv1_028843 CC(=O)n1c2C(C(=C(N)Oc2c3ccccc13)C#N)c4cc(Br)ccc4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P02 compound treatment 671390.0 207000.0 0.43 538293.0 103000.0 0.22 0.4604 0.9545 1672689 ChemDiv1_028844 CC1CC2(CC(C)(OC2=O)c3csc(Nc4ccc(C)cc4)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P03 compound treatment 671880.0 207000.0 0.43 544974.0 110000.0 0.24 0.4714 0.9617 1983408 ChemDiv1_028845 CC(=O)Oc1ccccc1c2nc3sc(=Cc4ccc(C)cc4)c(=O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P04 compound treatment 640479.0 176000.0 0.36 541480.0 107000.0 0.23 0.4202 0.976 1983409 ChemDiv1_028846 CCOC(=O)C1C(NC(=S)NC1(O)C(F)(F)F)c2ccc(O)c(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P05 compound treatment 642898.0 178000.0 0.37 560109.0 125000.0 0.27 0.4522 0.9886 1671753 ChemDiv1_028847 O=C(CSc1nnc2c3ccccc3[nH]c2n1)C4CC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P06 compound treatment 659163.0 195000.0 0.4 560799.0 126000.0 0.27 0.477 0.9821 1983410 ChemDiv1_028848 CC1(C)Cc2c(CO1)sc3nc[nH]c(=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P07 compound treatment 656791.0 192000.0 0.4 562407.0 128000.0 0.28 0.476 0.9842 1421054 ChemDiv1_028849 O=C1CCCc2oc3c(cc(NS(=O)(=O)c4ccc5ccccc5c4)c6ccccc36)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P08 compound treatment 667862.0 203000.0 0.42 569590.0 135000.0 0.29 0.5032 0.9841 1460054 ChemDiv1_028850 COc1c(Cl)c(Cl)ccc1S(=O)(=O)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P09 compound treatment 642950.0 179000.0 0.37 571615.0 137000.0 0.3 0.4699 0.9941 1983411 ChemDiv1_028851 CCC1(C)CC(CCNCc2ccc(OC)c(OC)c2)(CCO1)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P10 compound treatment 665137.0 201000.0 0.41 560350.0 125000.0 0.27 0.4851 0.979 1609354 ChemDiv1_028852 Cc1cc2NC(=O)CC(c3ccccc3Br)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P11 compound treatment 659803.0 195000.0 0.4 580702.0 146000.0 0.32 0.5084 0.9926 1374724 ChemDiv1_028853 CCOc1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(OC)c(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P12 compound treatment 647722.0 183000.0 0.38 554312.0 119000.0 0.26 0.4504 0.9828 1219889 ChemDiv1_028854 OC(CN(c1ccccc1)S(=O)(=O)c2ccccc2)CN3CCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P13 compound treatment 652187.0 188000.0 0.39 576991.0 142000.0 0.31 0.4916 0.9934 1549055 ChemDiv1_028855 Cc1cccc(c1)N2C(C(N3C(=O)c4ccccc4C3=O)C2=O)c5ccc(F)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P14 compound treatment 649143.0 185000.0 0.38 564849.0 130000.0 0.28 0.4686 0.9888 1983412 ChemDiv1_028856 CC(CCCCc1ccc(F)cc1)c2cc(O)c3C4=C(CCN(CC#C)C4)C(C)(C)Oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P15 compound treatment 669275.0 205000.0 0.42 599849.0 165000.0 0.36 0.5516 0.9965 1983413 ChemDiv1_028857 Clc1cc(Cl)cc(c1)N2C(C(N3C(=O)c4c(C3=O)c(Cl)c(Cl)c(Cl)c4Cl)C2=O)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P16 compound treatment 648676.0 184000.0 0.38 589563.0 155000.0 0.33 0.5057 0.998 1268164 ChemDiv1_028858 Oc1ccc(Br)cc1CN2CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P17 compound treatment 665835.0 201000.0 0.42 582447.0 148000.0 0.32 0.5199 0.9915 1926960 ChemDiv1_028859 CN1C(NC(=O)NC(C)(C)C)C(NC(=O)NC(C)(C)C)N(C)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P18 compound treatment 681848.0 217000.0 0.45 595588.0 161000.0 0.35 0.5634 0.9921 1618189 ChemDiv1_028860 CC1(C)CC2(CC(C)(OC2=O)c3csc(N)n3)C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P19 compound treatment 681300.0 217000.0 0.45 595023.0 160000.0 0.35 0.5617 0.992 1632233 ChemDiv1_028861 O=C(Nc1ccccn1)c2c(NC(=O)c3ccccc3)sc4CCCCCc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P20 compound treatment 667041.0 203000.0 0.42 601176.0 166000.0 0.36 0.5503 0.9972 1983414 ChemDiv1_028862 Brc1ccc2oc(=O)c(cc2c1)c3nc(c4ccccc4)c5cc(Br)ccc5n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P21 compound treatment 624195.0 160000.0 0.33 581222.0 146000.0 0.32 0.4572 0.9998 1983415 ChemDiv1_028863 CCCc1nc2SCC(=Nn2n1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P22 compound treatment 644246.0 180000.0 0.37 583606.0 149000.0 0.32 0.4902 0.9975 1119958 ChemDiv1_028864 CC(C)NC(=O)c1ccc2c3nc4ccccc4n3c(=S)[nH]c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P23 mock treatment 623328.0 159000.0 0.33 565130.0 130000.0 0.28 0.4313 0.9972 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.668 P24 mock treatment 180489.0 -284000.0 -0.59 436930.0 2080.0 0.0 -0.4113 -0.7017 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A01 mock treatment 16733.0 -212000.0 -0.44 15288.0 -210000.0 -0.45 -0.6305 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A02 mock treatment 17341.0 -211000.0 -0.44 17351.0 -208000.0 -0.45 -0.6264 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A03 compound treatment 575182.0 347000.0 0.72 526787.0 302000.0 0.65 0.9675 0.999 1923215 CBMicro_000001 Cc1cccc(NC(=O)/C=C/c2ccc(Cl)cc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A04 compound treatment 590007.0 361000.0 0.75 539400.0 314000.0 0.68 1.0085 0.9989 1664611 CBMicro_000002 Cc1cccc(NC(=O)COc2ccccc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A05 compound treatment 592136.0 364000.0 0.75 541769.0 317000.0 0.69 1.0152 0.999 1923216 CBMicro_000003 COc1cc(/C=N/n2c(C)nnc2C)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A06 compound treatment 602832.0 374000.0 0.77 577349.0 352000.0 0.76 1.0853 1.0 1437046 CBMicro_000004 O=S(=O)(Nc1ccc(OCc2ccccc2)cc1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A07 compound treatment 610583.0 382000.0 0.79 564064.0 339000.0 0.73 1.0762 0.9993 1923217 CBMicro_000005 CCOC(=O)C(C)P(=O)(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A08 compound treatment 616751.0 388000.0 0.8 587153.0 362000.0 0.78 1.1206 0.9999 1923218 CBMicro_000006 [O-][N+](=O)c1cccc2C(=O)N(N3C(=O)c4ccccc4C3=O)C(=O)c21 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A09 compound treatment 617059.0 388000.0 0.8 586860.0 362000.0 0.78 1.1206 0.9999 1923219 CBMicro_000007 O=C(Nc1ccc2OCOc2c1)C(=O)Nc3ccc4OCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A10 compound treatment 612913.0 384000.0 0.79 578352.0 353000.0 0.76 1.1015 0.9998 1700429 CBMicro_000008 O=C(COc1ccc2ccccc2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A11 compound treatment 610737.0 382000.0 0.79 569775.0 345000.0 0.75 1.0852 0.9996 1625595 CBMicro_000009 Cc1cc(C)c2oc(nc2c1)c3cccc(NC(=O)c4ccccc4C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A12 compound treatment 640493.0 412000.0 0.85 581342.0 356000.0 0.77 1.1463 0.9988 1179080 CBMicro_000010 COC(=O)c1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A13 compound treatment 669293.0 441000.0 0.91 584281.0 359000.0 0.78 1.1929 0.9969 1155892 CBMicro_000011 COc1ccc(CNS(=O)(=O)c2ccc(OC)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A14 compound treatment 638344.0 410000.0 0.85 573793.0 349000.0 0.75 1.1316 0.9984 1923220 CBMicro_000012 OCCCNC(=O)c1ccccc1NC(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A15 compound treatment 1200676.0 972000.0 2.01 593811.0 369000.0 0.8 1.9831 0.9183 1923221 CBMicro_000013 CCOC(=O)C(CC)P(=O)(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A16 compound treatment 641250.0 413000.0 0.85 646058.0 421000.0 0.91 1.2465 0.9994 1923222 CBMicro_000014 COc1ccc(cc1)C(=O)/C=C/c2ccc(\C=C\C(=O)c3ccc(OC)cc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A17 compound treatment 660689.0 432000.0 0.89 565581.0 340000.0 0.74 1.1517 0.9955 1923223 CBMicro_000015 Cc1cc(C)n(n1)C(=O)COc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A18 compound treatment 570847.0 342000.0 0.71 516513.0 291000.0 0.63 0.9455 0.9984 1923224 CBMicro_000016 [O-][N+](=O)c1ccccc1/C=C/2\SC(=N)NC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A19 compound treatment 606031.0 377000.0 0.78 549023.0 324000.0 0.7 1.0466 0.9986 1923225 CBMicro_000017 Cc1c(Cl)cccc1NC(=O)/C=C/c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A20 compound treatment 624644.0 396000.0 0.82 553133.0 328000.0 0.71 1.08 0.9975 1344693 CBMicro_000018 Oc1ccccc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)C(=O)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A21 compound treatment 596078.0 367000.0 0.76 565137.0 340000.0 0.74 1.0567 0.9999 1923226 CBMicro_000019 Cn1cnnc1SCC(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A22 compound treatment 578404.0 350000.0 0.72 537298.0 312000.0 0.68 0.9883 0.9994 1474845 CBMicro_000020 CCC(CC)NCc1cc(Br)ccc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A23 mock treatment 550203.0 322000.0 0.66 541497.0 316000.0 0.68 0.9536 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 A24 mock treatment 202595.0 -26000.0 -0.05 273310.0 48200.0 0.1 0.0357 0.3046 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B01 mock treatment 17184.0 -211000.0 -0.44 15634.0 -210000.0 -0.45 -0.6293 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B02 mock treatment 19058.0 -210000.0 -0.43 17351.0 -208000.0 -0.45 -0.6239 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B03 compound treatment 629258.0 401000.0 0.83 588255.0 363000.0 0.79 1.1405 0.9997 1923227 CBMicro_000021 C=CCN1C(=O)/C(=C\c2ccc(C=O)cc2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B04 compound treatment 623848.0 395000.0 0.82 689236.0 464000.0 1.0 1.2872 0.9947 1183696 CBMicro_000022 Clc1cccc(NC(=O)COc2ccccc2)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B05 compound treatment 643649.0 415000.0 0.86 622975.0 398000.0 0.86 1.2147 1.0 1476611 CBMicro_000023 COc1ccc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(C)c4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B06 compound treatment 647914.0 419000.0 0.87 585877.0 361000.0 0.78 1.1641 0.9987 1240051 CBMicro_000024 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)Nc4cccc(Cl)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B07 compound treatment 648536.0 420000.0 0.87 608526.0 383000.0 0.83 1.1997 0.9998 1185469 CBMicro_000025 Ic1cccc(NC(=O)c2ccc(cc2)c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B08 compound treatment 647175.0 419000.0 0.86 647849.0 423000.0 0.91 1.2579 0.9996 1923228 CBMicro_000026 CC1(C)CC(=O)C=C(C1)NNC(=O)c2ccc(O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B09 compound treatment 678197.0 450000.0 0.93 644949.0 420000.0 0.91 1.2987 0.9999 1538098 CBMicro_000027 COc1cccc(OC)c1C(=O)Nc2ccccc2I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B10 compound treatment 664629.0 436000.0 0.9 617094.0 392000.0 0.85 1.2363 0.9996 1923229 CBMicro_000028 CC(=O)N(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B11 compound treatment 689832.0 461000.0 0.95 652664.0 428000.0 0.93 1.3275 0.9999 1923230 CBMicro_000029 COc1ccc(CNC(=O)C(=O)Nc2cccc(Cl)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B12 compound treatment 661291.0 433000.0 0.89 606610.0 381000.0 0.83 1.2154 0.9992 1923231 CBMicro_000030 [O-][N+](=O)c1cccc(/C=C/C(=O)c2ccc3OCCOc3c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B13 compound treatment 691324.0 463000.0 0.96 647496.0 422000.0 0.91 1.3218 0.9998 1698658 CBMicro_000031 CC1CC(N(C(=O)c2ccco2)c3ccccc3)c4ccccc4N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B14 compound treatment 667391.0 439000.0 0.91 614083.0 389000.0 0.84 1.2357 0.9993 1923232 CBMicro_000032 [O-][N+](=O)c1ccc(NC(=O)COc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B15 compound treatment 692147.0 464000.0 0.96 631697.0 407000.0 0.88 1.2988 0.9991 1923233 CBMicro_000033 Clc1ccc(/C=C/2\SC(=N)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B16 compound treatment 689713.0 461000.0 0.95 614129.0 389000.0 0.84 1.2684 0.9981 1133273 CBMicro_000034 CCOc1cccc(c1)C2NC(=O)NC(=C2C(=O)OCc3ccc(OC)cc3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B17 compound treatment 680110.0 451000.0 0.93 642069.0 417000.0 0.9 1.2971 0.9999 1150721 CBMicro_000035 CC1=C(C(NC(=O)N1)c2ccccc2F)C(=O)OCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B18 compound treatment 656875.0 428000.0 0.88 599972.0 375000.0 0.81 1.1988 0.9991 1923234 CBMicro_000036 CC(C)CN(CC(C)C)C(=O)/C=C/c1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B19 compound treatment 666268.0 438000.0 0.9 617280.0 392000.0 0.85 1.239 0.9995 1923235 CBMicro_000037 OCCNC(=O)C(=O)NCc1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B20 compound treatment 710152.0 482000.0 0.99 628382.0 403000.0 0.87 1.32 0.9979 1923236 CBMicro_000038 CCOc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1OC(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B21 compound treatment 656424.0 428000.0 0.88 610370.0 385000.0 0.83 1.214 0.9996 1923237 CBMicro_000039 COc1ccc(cc1)S(=O)(=O)Nc2ccc(Br)cc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B22 compound treatment 599585.0 371000.0 0.77 563369.0 338000.0 0.73 1.0591 0.9997 1923238 CBMicro_000040 FC(F)C(F)(F)COC(=O)CCCC(=O)Nc1ccc(F)cc1F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B23 mock treatment 612259.0 384000.0 0.79 576783.0 352000.0 0.76 1.0981 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 B24 mock treatment 248744.0 20100.0 0.04 348036.0 123000.0 0.27 0.2174 0.8078 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C01 mock treatment 16953.0 -212000.0 -0.44 15728.0 -209000.0 -0.45 -0.6295 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C02 mock treatment 16314.0 -212000.0 -0.44 16346.0 -209000.0 -0.45 -0.6295 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C03 compound treatment 633014.0 404000.0 0.83 588416.0 363000.0 0.79 1.1462 0.9996 1404707 CBMicro_000041 Cc1c(Cl)cccc1NC(=O)COc2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C04 compound treatment 635943.0 407000.0 0.84 579203.0 354000.0 0.77 1.1364 0.9989 1923239 CBMicro_000042 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C05 compound treatment 649431.0 421000.0 0.87 599682.0 375000.0 0.81 1.1875 0.9994 1923240 CBMicro_000043 [O-][N+](=O)c1ccccc1C(=O)ON2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C06 compound treatment 648119.0 420000.0 0.87 600940.0 376000.0 0.81 1.1875 0.9995 1923241 CBMicro_000044 Clc1ccc(OCCCC(=O)NCCCn2ccnc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C07 compound treatment 664007.0 435000.0 0.9 635327.0 410000.0 0.89 1.2633 1.0 1923242 CBMicro_000045 CCP(=O)(CC)C(C)(C)CP(=O)(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C08 compound treatment 713443.0 485000.0 1.0 630339.0 405000.0 0.88 1.3278 0.9978 1023186 CBMicro_000046 Clc1ccc(cc1)N2C(=O)CSC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C09 compound treatment 698712.0 470000.0 0.97 632380.0 407000.0 0.88 1.3094 0.9988 1072093 CBMicro_000047 Oc1ccc(cc1)C(=S)N2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C10 compound treatment 678178.0 450000.0 0.93 630562.0 405000.0 0.88 1.2767 0.9996 1923243 CBMicro_000048 Cc1cc(C)c(c(C)c1)S(=O)(=O)c2ccccc2C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C11 compound treatment 684300.0 456000.0 0.94 629742.0 405000.0 0.88 1.2844 0.9994 1923244 CBMicro_000049 Brc1ccccc1C(=O)Nc2ccc(OCc3ccccc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C12 compound treatment 671922.0 443000.0 0.92 627523.0 402000.0 0.87 1.2629 0.9997 1657824 CBMicro_000050 OC(=O)c1ccc(CN2CCOCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C13 compound treatment 687414.0 459000.0 0.95 623437.0 398000.0 0.86 1.2792 0.9989 1923245 CBMicro_000051 CC(C)N(Cc1ccccc1)C(=O)CCCOc2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C14 compound treatment 684115.0 456000.0 0.94 634308.0 409000.0 0.89 1.2911 0.9996 1923246 CBMicro_000052 COc1ccc(cc1OC)C(=O)Nc2cc(ccc2Cl)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C15 compound treatment 701378.0 473000.0 0.98 649641.0 424000.0 0.92 1.3397 0.9995 1923247 CBMicro_000053 CCCS(=O)(=O)c1c(C(=O)c2ccc(cc2)[N+](=O)[O-])n3ccccc3c1S(=O)(=O)CCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C16 compound treatment 684474.0 456000.0 0.94 620578.0 395000.0 0.86 1.2706 0.9989 1923248 CBMicro_000054 COc1ccc(C=O)c2c(OC)cccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C17 compound treatment 698687.0 470000.0 0.97 638890.0 414000.0 0.9 1.3194 0.9992 1923249 CBMicro_000055 Fc1ccc(cc1)C2=N/C(=C\c3ccc4OCOc4c3)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C18 compound treatment 660358.0 432000.0 0.89 619412.0 394000.0 0.85 1.2336 0.9998 1261766 CBMicro_000056 Clc1ccc(NC(=O)COc2ccc(Cl)cc2Cl)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C19 compound treatment 698697.0 470000.0 0.97 623888.0 399000.0 0.86 1.2964 0.9983 1923250 CBMicro_000057 Cc1ccc(C)c(NC(=O)/C=C/c2ccc(Cl)cc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C20 compound treatment 644096.0 415000.0 0.86 594452.0 369000.0 0.8 1.1717 0.9994 1778663 CBMicro_000058 [O-][N+](=O)c1ccc(cc1)c2ccc(NC(=O)c3cccs3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C21 compound treatment 664067.0 435000.0 0.9 618482.0 393000.0 0.85 1.2376 0.9996 1923251 CBMicro_000059 CCCOC(=O)c1ccc(NC(=O)/C=C\C(=O)O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C22 compound treatment 724863.0 496000.0 1.02 571019.0 346000.0 0.75 1.2537 0.9881 1586771 CBMicro_000060 CN(C)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C23 mock treatment 618431.0 390000.0 0.8 580087.0 355000.0 0.77 1.1122 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 C24 mock treatment 217014.0 -11600.0 -0.02 215486.0 -9670.0 -0.02 -0.0317 -0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D01 mock treatment 16482.0 -212000.0 -0.44 15738.0 -209000.0 -0.45 -0.6302 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D02 mock treatment 16733.0 -212000.0 -0.44 16074.0 -209000.0 -0.45 -0.6293 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D03 compound treatment 638762.0 410000.0 0.85 589218.0 364000.0 0.79 1.1559 0.9994 1923252 CBMicro_000061 CCOC(=O)c1c(NC(=O)/C=C/c2ccco2)sc3CCCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D04 compound treatment 644914.0 416000.0 0.86 595647.0 370000.0 0.8 1.1747 0.9994 1923253 CBMicro_000062 CCOC(=O)c1conc1c2ccc(Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D05 compound treatment 641825.0 413000.0 0.85 611069.0 386000.0 0.84 1.1938 0.9999 1923254 CBMicro_000063 Brc1ccc(cc1)c2nocc2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D06 compound treatment 646737.0 418000.0 0.86 594737.0 370000.0 0.8 1.176 0.9993 1923255 CBMicro_000064 CC(C)(C)C1CCC2(CC1)NNC(=S)NN2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D07 compound treatment 6435135.0 6210000.0 12.81 5649585.0 5420000.0 11.74 17.3614 0.999 1125544 CBMicro_000065 O=C1c2ccccc2-c3onc4ccc(N5CCCCC5)c1c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D08 compound treatment 657851.0 429000.0 0.89 624850.0 400000.0 0.87 1.2383 0.9999 1923256 CBMicro_000066 COc1cccc(C=C2C(=O)NC(=S)NC2=O)c1OCC#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D09 compound treatment 681507.0 453000.0 0.93 663354.0 438000.0 0.95 1.3317 1.0 1445986 CBMicro_000067 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D10 compound treatment 685296.0 457000.0 0.94 639711.0 415000.0 0.9 1.3011 0.9997 1252079 CBMicro_000068 COc1ccc(NC(=O)c2ccc(OC)c(OC)c2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D11 compound treatment 678283.0 450000.0 0.93 651827.0 427000.0 0.92 1.3094 1.0 1923257 CBMicro_000069 Clc1ccccc1/C=C\2/SC(=N)NC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D12 compound treatment 679908.0 451000.0 0.93 633750.0 409000.0 0.88 1.2841 0.9997 1923258 CBMicro_000070 COc1ccc(OCCNc2cc(Cl)ccc2[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D13 compound treatment 699350.0 471000.0 0.97 630722.0 406000.0 0.88 1.3078 0.9987 1428330 CBMicro_000071 CC1CC(C)(C)N(c2ccccc12)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D14 compound treatment 663852.0 435000.0 0.9 636139.0 411000.0 0.89 1.2643 1.0 1923259 CBMicro_000072 CC1=C(C(NC(=O)N1)c2ccc(O)c(c2)[N+](=O)[O-])C(=O)OCc3ccc4OCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D15 compound treatment 697833.0 469000.0 0.97 665720.0 441000.0 0.95 1.3592 1.0 1923260 CBMicro_000073 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D16 compound treatment 695439.0 467000.0 0.96 636630.0 411000.0 0.89 1.3112 0.9992 1633745 CBMicro_000074 COC(=O)c1ccccc1N(Cc2ccccc2)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D17 compound treatment 685179.0 457000.0 0.94 641731.0 417000.0 0.9 1.304 0.9998 1923261 CBMicro_000075 COc1ccc2oc(cc(=O)c2c1)C(Cl)(Cl)Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D18 compound treatment 659366.0 431000.0 0.89 623264.0 398000.0 0.86 1.238 0.9999 1923262 CBMicro_000076 [O-][N+](=O)c1ccccc1c2ccc(/C=C/C(=O)c3ccc(F)cc3)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D19 compound treatment 683543.0 455000.0 0.94 641019.0 416000.0 0.9 1.3005 0.9998 1383810 CBMicro_000077 OC(=O)c1ccccc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D20 compound treatment 682060.0 453000.0 0.94 652796.0 428000.0 0.93 1.3164 1.0 1923263 CBMicro_000078 CCOc1cc(/C=C/2\SC(=S)N(C2=O)c3ccccc3)ccc1OC(=O)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D21 compound treatment 633533.0 405000.0 0.84 604509.0 379000.0 0.82 1.1716 1.0 1923264 CBMicro_000079 COc1ccc(C=O)c2c(O)cccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D22 compound treatment 632011.0 403000.0 0.83 586985.0 362000.0 0.78 1.1426 0.9995 1923265 CBMicro_000080 CCOP(=O)(CCN(CC)CC)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D23 mock treatment 624708.0 396000.0 0.82 584971.0 360000.0 0.78 1.1288 0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 D24 mock treatment 207527.0 -21100.0 -0.04 260315.0 35200.0 0.08 0.023 0.2627 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E01 mock treatment 15749.0 -213000.0 -0.44 16304.0 -209000.0 -0.45 -0.6304 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E02 mock treatment 15278.0 -213000.0 -0.44 14628.0 -211000.0 -0.46 -0.6336 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E03 compound treatment 632902.0 404000.0 0.83 568744.0 344000.0 0.74 1.116 0.9983 1923266 CBMicro_000081 Clc1ccccc1/C=C/C(=O)Nc2nccs2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E04 compound treatment 642577.0 414000.0 0.85 567911.0 343000.0 0.74 1.1288 0.9975 1923267 CBMicro_000082 COc1ccc(Cl)cc1NC(=O)c2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E05 compound treatment 655955.0 427000.0 0.88 608488.0 383000.0 0.83 1.2105 0.9995 1724203 CBMicro_000083 O=C(N1CCOCC1)n2nnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E06 compound treatment 685067.0 456000.0 0.94 600193.0 375000.0 0.81 1.2402 0.9972 1599451 CBMicro_000084 COc1ccc(CNS(=O)(=O)c2ccc(C)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E07 compound treatment 693411.0 465000.0 0.96 655737.0 431000.0 0.93 1.3374 0.9999 1923268 CBMicro_000085 OC1(c2ccccc2-c3ncccc31)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E08 compound treatment 684082.0 455000.0 0.94 602610.0 377000.0 0.82 1.2425 0.9975 1470304 CBMicro_000086 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(O)c(CN(C)C)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E09 compound treatment 718014.0 489000.0 1.01 627266.0 402000.0 0.87 1.3298 0.9972 1923269 CBMicro_000087 CC(NC(=O)c1ccccc1Cl)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E10 compound treatment 670984.0 442000.0 0.91 621014.0 396000.0 0.86 1.2516 0.9995 1923270 CBMicro_000088 CC(=O)c1cccc(NC(=O)Nc2cccc3ccccc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E11 compound treatment 795466.0 567000.0 1.17 647480.0 422000.0 0.91 1.4738 0.9925 1923271 CBMicro_000089 CC1CCN(CC1)C(=O)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E12 compound treatment 692317.0 464000.0 0.96 627935.0 403000.0 0.87 1.2933 0.9989 1411639 CBMicro_000090 COc1ccc(CNc2cccc(SC)c2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E13 compound treatment 740861.0 512000.0 1.06 632719.0 408000.0 0.88 1.3715 0.9959 1923272 CBMicro_000091 [O-][N+](=O)c1ccccc1S(=O)(=O)Nc2ccc(OCc3ccccc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E14 compound treatment 668052.0 439000.0 0.91 607140.0 382000.0 0.83 1.226 0.9989 1454503 CBMicro_000092 COc1ccc(C)cc1NC(=O)c2cccc(I)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E15 compound treatment 713306.0 485000.0 1.0 642291.0 417000.0 0.9 1.3459 0.9987 1356945 CBMicro_000093 COc1ccc(Nc2nc(cs2)c3ccc(Cl)c(Cl)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E16 compound treatment 710439.0 482000.0 0.99 620375.0 395000.0 0.86 1.3082 0.9972 1401790 CBMicro_000094 Cc1ccc(cc1C)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E17 compound treatment 729862.0 501000.0 1.03 633966.0 409000.0 0.88 1.3573 0.997 1923273 CBMicro_000095 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3oc(nc3c2)c4cccc(Br)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E18 compound treatment 681806.0 453000.0 0.94 611150.0 386000.0 0.84 1.2523 0.9984 1923274 CBMicro_000096 COc1cccc(NC(=O)C(=O)NCC(C)C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E19 compound treatment 685846.0 457000.0 0.94 615980.0 391000.0 0.85 1.2655 0.9985 1923275 CBMicro_000097 CCOc1ccc(NC(=O)/C=C/c2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E20 compound treatment 670735.0 442000.0 0.91 594480.0 369000.0 0.8 1.2106 0.9978 1223119 CBMicro_000098 Cc1cccc(Cc2cnc(N)s2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E21 compound treatment 701016.0 472000.0 0.98 618927.0 394000.0 0.85 1.2922 0.9977 1338620 CBMicro_000099 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2cccc(Cl)c2)Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E22 compound treatment 657300.0 429000.0 0.88 585820.0 361000.0 0.78 1.1777 0.998 1242474 CBMicro_000100 Fc1ccc(cc1)S(=O)(=O)Nc2cccnc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E23 mock treatment 663391.0 435000.0 0.9 589354.0 364000.0 0.79 1.192 0.9979 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 E24 mock treatment 212103.0 -16500.0 -0.03 295154.0 70000.0 0.15 0.083 0.5347 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F01 mock treatment 15456.0 -213000.0 -0.44 16074.0 -209000.0 -0.45 -0.6311 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F02 mock treatment 15236.0 -213000.0 -0.44 16074.0 -209000.0 -0.45 -0.6315 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F03 compound treatment 634629.0 406000.0 0.84 596601.0 371000.0 0.8 1.1611 0.9998 1923276 CBMicro_000101 Cc1cccc(N2C(=O)c3ccc(Oc4ccc(cc4)[N+](=O)[O-])cc3C2=O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F04 compound treatment 641161.0 413000.0 0.85 590758.0 366000.0 0.79 1.1617 0.9993 1923277 CBMicro_000102 CCC(=O)CC(O)(c1ccccc1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F05 compound treatment 662031.0 433000.0 0.89 636823.0 412000.0 0.89 1.2627 1.0 1923278 CBMicro_000103 [O-][N+](=O)c1cccc(/C=C\2/C(=O)NN(C2=O)c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F06 compound treatment 620970.0 392000.0 0.81 603605.0 378000.0 0.82 1.1519 1.0 1923279 CBMicro_000104 [O-][N+](=O)c1ccc2NC(=O)C3(NN=C(S3)c4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F07 compound treatment 669234.0 441000.0 0.91 659141.0 434000.0 0.94 1.3074 0.9999 1923280 CBMicro_000105 CCC(C)(c1ccc(C=O)s1)c2ccc(C=O)s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F08 compound treatment 661608.0 433000.0 0.89 623953.0 399000.0 0.86 1.2424 0.9998 1923281 CBMicro_000106 S=C(Nc1ccccc1)Nc2ccc(C#N)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F09 compound treatment 677046.0 448000.0 0.93 661948.0 437000.0 0.95 1.3231 0.9999 1567239 CBMicro_000107 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2c(OC)cccc2OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F10 compound treatment 661758.0 433000.0 0.89 630142.0 405000.0 0.88 1.2521 1.0 1923282 CBMicro_000108 COc1cccc(OCCNc2cc(Cl)ccc2[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F11 compound treatment 697092.0 468000.0 0.97 936277.0 711000.0 1.54 1.7722 0.9749 1923283 CBMicro_000109 COCCNC(=O)C(=O)Nc1cccc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F12 compound treatment 674138.0 446000.0 0.92 650144.0 425000.0 0.92 1.3007 1.0 1923284 CBMicro_000110 [O-][N+](=O)c1ccc(NCCNC(=O)c2cccc(Br)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F13 compound treatment 695725.0 467000.0 0.96 688518.0 463000.0 1.0 1.391 0.9998 1923285 CBMicro_000111 COc1ccc(cc1)C(=O)CSc2nc(C)cc(C)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F14 compound treatment 760531.0 532000.0 1.1 658336.0 433000.0 0.94 1.4394 0.9969 1695675 CBMicro_000112 Cc1ccc(N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F15 compound treatment 703069.0 474000.0 0.98 667340.0 442000.0 0.96 1.3693 0.9999 1719298 CBMicro_000113 CC1(C2C(C(=O)NC2=O)C3(C)c4ccccc41)c5ccccc53 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F16 compound treatment 658354.0 430000.0 0.89 638843.0 414000.0 0.9 1.2604 1.0 1923286 CBMicro_000114 CSCCOC(=O)C1=C(C)NC(=O)NC1c2ccc(O)c(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F17 compound treatment 1824706.0 1600000.0 3.29 1893215.0 1670000.0 3.61 4.8827 0.999 1923287 CBMicro_000115 CCOc1cc(/C=N/N2C(=O)/C(=C/c3ccc(O)c(OCC)c3)/SC2=S)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F18 compound treatment 702404.0 474000.0 0.98 634316.0 409000.0 0.89 1.3178 0.9988 1923288 CBMicro_000116 COc1cccc(c1)C(c2c(O)c3ccccc3oc2=O)c4c(O)c5ccccc5oc4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F19 compound treatment 679588.0 451000.0 0.93 655951.0 431000.0 0.93 1.3176 1.0 1923289 CBMicro_000117 Cc1cccc(N2C(=O)c3ccc(Oc4cccc(c4)[N+](=O)[O-])cc3C2=O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F20 compound treatment 674811.0 446000.0 0.92 693984.0 469000.0 1.01 1.3688 0.9988 1923290 CBMicro_000118 CCOC(=O)CCN(CP(=O)(C)OC(C)C)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F21 compound treatment 671759.0 443000.0 0.91 705908.0 481000.0 1.04 1.3826 0.9979 1923291 CBMicro_000119 COc1ccccc1CNCCc2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F22 compound treatment 623908.0 395000.0 0.82 613193.0 388000.0 0.84 1.1709 0.9999 1923292 CBMicro_000120 CC(C)OP(=O)(C)CN(CC=C)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F23 mock treatment 635448.0 407000.0 0.84 606870.0 382000.0 0.83 1.178 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 F24 mock treatment 224638.0 -3970.0 -0.01 303919.0 78800.0 0.17 0.1147 0.6723 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G01 mock treatment 16838.0 -212000.0 -0.44 16136.0 -209000.0 -0.45 -0.629 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G02 mock treatment 15770.0 -213000.0 -0.44 14115.0 -211000.0 -0.46 -0.6337 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G03 compound treatment 636655.0 408000.0 0.84 583302.0 358000.0 0.78 1.1437 0.9991 1923293 CBMicro_000121 CCOC(=O)c1cccc(NC(=O)/C=C/c2ccccc2Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G04 compound treatment 639851.0 411000.0 0.85 566411.0 341000.0 0.74 1.1225 0.9976 1923294 CBMicro_000122 [O-][N+](=O)c1ccccc1C(=O)Nc2ccccc2I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G05 compound treatment 654914.0 426000.0 0.88 595423.0 370000.0 0.8 1.1889 0.9989 1923295 CBMicro_000123 CCc1ccccc1NC(=O)/C=C/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G06 compound treatment 639406.0 411000.0 0.85 594928.0 370000.0 0.8 1.1655 0.9996 1362228 CBMicro_000124 Clc1ccc(cc1)C(=O)N2CCC(Cc3ccccc3)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G07 compound treatment 669307.0 441000.0 0.91 626013.0 401000.0 0.87 1.2568 0.9997 1407226 CBMicro_000125 CN1C(CC(O)(CC1c2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G08 compound treatment 669280.0 441000.0 0.91 634408.0 409000.0 0.89 1.2696 0.9999 1015525 CBMicro_000126 OC(C(=O)Nc1ccccn1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G09 compound treatment 685378.0 457000.0 0.94 635695.0 411000.0 0.89 1.295 0.9996 1923296 CBMicro_000127 COc1ccc(cc1)C(=O)Nc2cc(ccc2Cl)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G10 compound treatment 678316.0 450000.0 0.93 623364.0 398000.0 0.86 1.2659 0.9993 1638944 CBMicro_000128 COc1ccc(NC2(OC(=O)c3ccccc32)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G11 compound treatment 710026.0 481000.0 0.99 665574.0 440000.0 0.95 1.3767 0.9998 1923297 CBMicro_000129 CC1CC(C)CN(C1)C(=O)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G12 compound treatment 681469.0 453000.0 0.93 613607.0 388000.0 0.84 1.2555 0.9986 1185006 CBMicro_000130 Cc1ccc2c(C)nc(Nc3nc(O)c4ccccc4n3)nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G13 compound treatment 701500.0 473000.0 0.98 648946.0 424000.0 0.92 1.3389 0.9995 1531984 CBMicro_000131 Clc1ccccc1C(=O)N2CCc3ccccc3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G14 compound treatment 702414.0 474000.0 0.98 631275.0 406000.0 0.88 1.3131 0.9986 1923298 CBMicro_000132 Cc1cccc(NC(=O)Cc2ccccc2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G15 compound treatment 710267.0 482000.0 0.99 670671.0 446000.0 0.96 1.3849 0.9999 1670166 CBMicro_000133 CCCc1nc2n(Cc3ccccc3)nnc2c(=O)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G16 compound treatment 699649.0 471000.0 0.97 660969.0 436000.0 0.94 1.3545 0.9999 1923299 CBMicro_000134 CCOc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G17 compound treatment 737357.0 509000.0 1.05 649384.0 424000.0 0.92 1.3919 0.9978 1923300 CBMicro_000135 CCC(C(=O)O)P(=O)(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G18 compound treatment 699371.0 471000.0 0.97 617391.0 392000.0 0.85 1.2874 0.9977 1923301 CBMicro_000136 CC(=O)c1cccc(c1)N2C(=O)c3ccc(Oc4ccc(cc4)[N+](=O)[O-])cc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G19 compound treatment 706989.0 478000.0 0.99 627817.0 403000.0 0.87 1.3145 0.9981 1923302 CBMicro_000137 COc1cccc2sc(NC(=O)/C=C/c3ccc(cc3)[N+](=O)[O-])nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G20 compound treatment 633384.0 405000.0 0.84 574093.0 349000.0 0.76 1.1249 0.9987 1923303 CBMicro_000138 [O-][N+](=O)c1ccccc1NC(=O)/C=C/c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G21 compound treatment 2685895.0 2460000.0 5.07 2251724.0 2030000.0 4.39 6.6884 0.9974 1923304 CBMicro_000139 OC(=O)c1cc(ccc1O)c2ccc(/C=C\3/Sc4ccccc4C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G22 compound treatment 668877.0 440000.0 0.91 597251.0 372000.0 0.81 1.2121 0.9982 1923305 CBMicro_000140 [O-][N+](=O)c1cccc(NC(=O)COc2ccccc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G23 mock treatment 659330.0 431000.0 0.89 608388.0 383000.0 0.83 1.2152 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 G24 mock treatment 219161.0 -9450.0 -0.02 215569.0 -9590.0 -0.02 -0.0285 -0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H01 mock treatment 15634.0 -213000.0 -0.44 16409.0 -209000.0 -0.45 -0.6304 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H02 mock treatment 15005.0 -214000.0 -0.44 13885.0 -211000.0 -0.46 -0.6351 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H03 compound treatment 631271.0 403000.0 0.83 583302.0 358000.0 0.78 1.1359 0.9994 1546765 CBMicro_000141 COc1ccc2oc(=O)c(cc2c1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H04 compound treatment 631156.0 403000.0 0.83 558737.0 334000.0 0.72 1.0981 0.9975 1699854 CBMicro_000142 CCOc1ccc(cc1)C(=O)Nc2ccncc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H05 compound treatment 651575.0 423000.0 0.87 605716.0 381000.0 0.82 1.1998 0.9996 1655866 CBMicro_000143 O=C(Nc1c[nH]c(=O)[nH]c1=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccccc4c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H06 compound treatment 633480.0 405000.0 0.84 598834.0 374000.0 0.81 1.1629 0.9999 1923306 CBMicro_000144 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H07 compound treatment 648388.0 420000.0 0.87 619384.0 394000.0 0.85 1.2161 1.0 1632859 CBMicro_000145 COc1ccc(cc1Br)C(=O)Nc2nc3ccc(C)cc3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H08 compound treatment 639190.0 411000.0 0.85 614603.0 389000.0 0.84 1.1953 1.0 1240178 CBMicro_000146 Clc1ccc(cc1)c2ccc(o2)C(=O)Nc3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H09 compound treatment 664995.0 436000.0 0.9 636618.0 411000.0 0.89 1.2667 1.0 1923307 CBMicro_000147 CCCSc1nnc(o1)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H10 compound treatment 649855.0 421000.0 0.87 617438.0 392000.0 0.85 1.2152 0.9999 1421671 CBMicro_000148 CC1C(N(C)C(C(C)C1(O)Cc2ccccc2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H11 compound treatment 684324.0 456000.0 0.94 638564.0 413000.0 0.89 1.2979 0.9997 1923308 CBMicro_000149 CCOc1ccc2S/C(=C\NCCc3ccccc3)/C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H12 compound treatment 664670.0 436000.0 0.9 616834.0 392000.0 0.85 1.2359 0.9996 1923309 CBMicro_000150 COc1ccc(/C=C/2\SC(=O)N(C2=O)c3cccc(C)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H13 compound treatment 666898.0 438000.0 0.9 625011.0 400000.0 0.87 1.2517 0.9998 1923310 CBMicro_000151 Cc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCCc5ccccc45)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H14 compound treatment 658650.0 430000.0 0.89 634525.0 409000.0 0.89 1.2542 1.0 1923311 CBMicro_000152 O=C(/C=C/c1ccc(OCc2ccccc2)cc1)c3ccc4OCCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H15 compound treatment 696830.0 468000.0 0.97 682399.0 457000.0 0.99 1.3832 0.9999 1923312 CBMicro_000153 O=C1NC(=O)C(=Cc2ccccc2OCCOc3ccccc3)C(=O)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H16 compound treatment 687326.0 459000.0 0.95 918403.0 693000.0 1.5 1.7306 0.9754 1453788 CBMicro_000154 Clc1ccc(OCC(=O)NS(=O)(=O)c2ccccc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H17 compound treatment 680248.0 452000.0 0.93 666774.0 442000.0 0.96 1.3351 0.9999 1923313 CBMicro_000155 COc1ccc2c(=O)cc(oc2c1)C(F)(F)C(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H18 compound treatment 653229.0 425000.0 0.88 625672.0 401000.0 0.87 1.2328 1.0 1923314 CBMicro_000156 CC(C)OC(=O)/C=C(\N)/c1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H19 compound treatment 667428.0 439000.0 0.91 636525.0 411000.0 0.89 1.2701 1.0 1239457 CBMicro_000157 Cc1cc(Br)ccc1NCc2ccccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H20 compound treatment 641348.0 413000.0 0.85 636781.0 412000.0 0.89 1.2324 0.9998 1923315 CBMicro_000158 Clc1ccc(COc2ccccc2/C=C/3\SC(=S)NC3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H21 compound treatment 673384.0 445000.0 0.92 625680.0 401000.0 0.87 1.2622 0.9996 1923316 CBMicro_000159 OCCCNC(=O)C(=O)Nc1ccc(F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H22 compound treatment 619487.0 391000.0 0.81 600447.0 375000.0 0.81 1.1449 1.0 1923317 CBMicro_000160 Fc1ccc(CC(=O)Nc2ccc(Cl)cc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H23 mock treatment 612015.0 383000.0 0.79 599765.0 375000.0 0.81 1.133 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 H24 mock treatment 247278.0 18700.0 0.04 244440.0 19300.0 0.04 0.0568 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I01 mock treatment 15770.0 -213000.0 -0.44 15320.0 -210000.0 -0.45 -0.6318 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I02 mock treatment 15602.0 -213000.0 -0.44 13874.0 -211000.0 -0.46 -0.6343 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I03 compound treatment 643541.0 415000.0 0.86 583539.0 358000.0 0.78 1.1541 0.9988 1923318 CBMicro_000161 Clc1ccccc1/C=C/C(=O)N2CCCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I04 compound treatment 645530.0 417000.0 0.86 573626.0 348000.0 0.75 1.1419 0.9978 1923319 CBMicro_000162 CC1CC(C)CN(C1)C(=O)c2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I05 compound treatment 666636.0 438000.0 0.9 594104.0 369000.0 0.8 1.204 0.9981 1923320 CBMicro_000163 Oc1ccc(CCN/C=C\2/C(=O)CNC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I06 compound treatment 641186.0 413000.0 0.85 594038.0 369000.0 0.8 1.1668 0.9995 1923321 CBMicro_000164 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I07 compound treatment 676339.0 448000.0 0.92 610370.0 385000.0 0.83 1.2431 0.9987 1075879 CBMicro_000165 Clc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I08 compound treatment 671745.0 443000.0 0.91 622243.0 397000.0 0.86 1.2546 0.9995 1619105 CBMicro_000166 O=C(Nc1ccccc1C(=O)N2CCCC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I09 compound treatment 662467.0 434000.0 0.9 569798.0 345000.0 0.75 1.1607 0.9959 1923322 CBMicro_000167 Cc1cccc(OCC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I10 compound treatment 666051.0 437000.0 0.9 608442.0 383000.0 0.83 1.2251 0.9991 1923323 CBMicro_000168 [O-][N+](=O)c1ccccc1NC(=O)COc2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I11 compound treatment 703761.0 475000.0 0.98 645107.0 420000.0 0.91 1.3363 0.9993 1923324 CBMicro_000169 COC(=O)c1cc(NS(=O)(=O)c2c(C)cc(C)cc2C)cc(c1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I12 compound treatment 666792.0 438000.0 0.9 615061.0 390000.0 0.84 1.2363 0.9994 1604325 CBMicro_000170 Cc1ccc(C(=O)CC(=O)c2ccccc2C)c(O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I13 compound treatment 699329.0 471000.0 0.97 644053.0 419000.0 0.91 1.3282 0.9994 1180761 CBMicro_000171 CC(NS(=O)(=O)c1ccc2OCCOc2c1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I14 compound treatment 698686.0 470000.0 0.97 634829.0 410000.0 0.89 1.3131 0.999 1223175 CBMicro_000172 OC(=O)c1ccc(Oc2cccc(NC(=O)c3ccc(cc3)c4ccccc4)c2)cc1C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I15 compound treatment 729217.0 501000.0 1.03 653062.0 428000.0 0.93 1.3856 0.9985 1349745 CBMicro_000173 OP(=O)(CP(=O)(O)c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I16 compound treatment 670177.0 442000.0 0.91 623877.0 399000.0 0.86 1.2548 0.9996 1156946 CBMicro_000174 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2ccc(O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I17 compound treatment 707548.0 479000.0 0.99 665142.0 440000.0 0.95 1.3725 0.9998 1923325 CBMicro_000175 O=C(Nc1ccc(Nc2ccccc2)c3C(=O)c4ccccc4C(=O)c13)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I18 compound treatment 731655.0 503000.0 1.04 615811.0 391000.0 0.85 1.3322 0.9948 1923326 CBMicro_000176 Cc1ccc(NC(=O)C(=O)NCCCO)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I19 compound treatment 684082.0 455000.0 0.94 629447.0 404000.0 0.88 1.2836 0.9994 1923327 CBMicro_000177 O=C(c1ccccc1)c2ccc3[nH]c(nc3c2)c4cccnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I20 compound treatment 674688.0 446000.0 0.92 622556.0 397000.0 0.86 1.2593 0.9994 1609110 CBMicro_000178 Cc1onc(c1C(=O)NCc2ccncc2)c3c(Cl)cccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I21 compound treatment 686309.0 458000.0 0.94 624502.0 399000.0 0.86 1.2793 0.999 1923328 CBMicro_000179 COc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I22 compound treatment 633804.0 405000.0 0.84 600207.0 375000.0 0.81 1.1654 0.9999 1923329 CBMicro_000180 CCN(CC)c1ccc(cc1)N2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I23 mock treatment 638800.0 410000.0 0.85 566451.0 341000.0 0.74 1.1211 0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 I24 mock treatment 226261.0 -2350.0 0.0 228481.0 3320.0 0.01 0.0017 0.1903 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J01 mock treatment 15173.0 -213000.0 -0.44 15948.0 -209000.0 -0.45 -0.6317 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J02 mock treatment 14869.0 -214000.0 -0.44 14587.0 -211000.0 -0.46 -0.6343 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J03 compound treatment 596933.0 368000.0 0.76 570550.0 345000.0 0.75 1.0662 1.0 1923330 CBMicro_000181 COc1cc(/C=N/Nc2ccnc3cc(Cl)ccc23)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J04 compound treatment 609618.0 381000.0 0.79 600167.0 375000.0 0.81 1.1301 0.9999 1923331 CBMicro_000182 CCOC(=O)c1cccc(NC(=O)/C=C/c2ccccc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J05 compound treatment 639397.0 411000.0 0.85 609834.0 385000.0 0.83 1.1883 1.0 1923332 CBMicro_000183 Cc1onc(c1C(=O)N)c2c(Cl)cccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J06 compound treatment 609291.0 381000.0 0.79 599588.0 374000.0 0.81 1.1287 0.9999 1923333 CBMicro_000184 [O-][N+](=O)c1ccccc1C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J07 compound treatment 686275.0 458000.0 0.94 636182.0 411000.0 0.89 1.2971 0.9995 1216889 CBMicro_000185 C(Sc1ncnc2nc[nH]c12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J08 compound treatment 638564.0 410000.0 0.85 630458.0 405000.0 0.88 1.2187 0.9998 1923334 CBMicro_000186 COc1ccccc1N/C(=N/OC(=O)C)/c2nonc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J09 compound treatment 671721.0 443000.0 0.91 649318.0 424000.0 0.92 1.296 1.0 1505061 CBMicro_000187 COC(=O)c1cc(NC(=O)c2ccccc2Br)cc(c1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J10 compound treatment 697071.0 468000.0 0.97 635452.0 410000.0 0.89 1.3117 0.9991 1680887 CBMicro_000188 Cc1nccn1S(=O)(=O)c2ccc(Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J11 compound treatment 666870.0 438000.0 0.9 653539.0 428000.0 0.93 1.2953 0.9999 1923335 CBMicro_000189 COc1ccc(CCNCc2cccc(Br)c2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J12 compound treatment 651791.0 423000.0 0.87 633454.0 408000.0 0.88 1.2426 1.0 1923336 CBMicro_000190 CCOc1ccc(cc1)N2C(=O)S/C(=C\c3ccc(OC)cc3)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J13 compound treatment 683277.0 455000.0 0.94 657058.0 432000.0 0.93 1.3247 1.0 1329858 CBMicro_000191 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccc(Br)cc4)C(=O)CC(C)(C)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J14 compound treatment 666529.0 438000.0 0.9 705495.0 480000.0 1.04 1.3744 0.9976 1923337 CBMicro_000192 [O-][N+](=O)c1ccc(NCCCNC(=O)c2cccc(Br)c2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J15 compound treatment 706507.0 478000.0 0.99 668556.0 443000.0 0.96 1.3762 0.9999 1923338 CBMicro_000193 Cc1cc(C)nc(NC(=N)Nc2cc(Cl)cc(Cl)c2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J16 compound treatment 653508.0 425000.0 0.88 655234.0 430000.0 0.93 1.2784 0.9996 1621690 CBMicro_000194 Cc1cn(cn1)S(=O)(=O)c2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J17 compound treatment 676794.0 448000.0 0.93 666875.0 442000.0 0.96 1.3302 0.9999 1923339 CBMicro_000195 CCOC(=O)c1ccccc1NC(=O)c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J18 compound treatment 664222.0 436000.0 0.9 660349.0 435000.0 0.94 1.3019 0.9997 1165590 CBMicro_000196 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J19 compound treatment 673691.0 445000.0 0.92 648541.0 423000.0 0.92 1.2976 1.0 1923340 CBMicro_000197 Cc1ccc(CNC(=O)c2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J20 compound treatment 643002.0 414000.0 0.86 630784.0 406000.0 0.88 1.2257 0.9999 1923341 CBMicro_000198 Cc1ccc(NC(=O)Cc2ccc(F)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J21 compound treatment 703207.0 475000.0 0.98 656728.0 432000.0 0.93 1.3533 0.9997 1923342 CBMicro_000199 CCOC(=O)c1ccc(N/C=C/C(=O)c2cccs2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J22 compound treatment 630920.0 402000.0 0.83 618736.0 394000.0 0.85 1.1896 0.9999 1657231 CBMicro_000200 Fc1ccc(CC(=O)Nc2ccccc2Br)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J23 mock treatment 635603.0 407000.0 0.84 621650.0 396000.0 0.86 1.2009 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 J24 mock treatment 190238.0 -38400.0 -0.08 293049.0 67900.0 0.15 0.0479 0.2869 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K01 mock treatment 15550.0 -213000.0 -0.44 14922.0 -210000.0 -0.46 -0.6328 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K02 mock treatment 15152.0 -213000.0 -0.44 15037.0 -210000.0 -0.45 -0.6332 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K03 compound treatment 620778.0 392000.0 0.81 572078.0 347000.0 0.75 1.1034 0.9993 1923343 CBMicro_000201 CCOC(=O)c1ccc(NC(=O)/C=C/c2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K04 compound treatment 619757.0 391000.0 0.81 560031.0 335000.0 0.72 1.0835 0.9985 1923344 CBMicro_000202 CCCOC(=O)c1ccc(NC(=O)c2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K05 compound treatment 647310.0 419000.0 0.86 580035.0 355000.0 0.77 1.1543 0.9983 1923345 CBMicro_000203 CCOc1ccc(NC(=O)/C=C/c2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K06 compound treatment 638877.0 410000.0 0.85 570479.0 345000.0 0.75 1.1274 0.9981 1923346 CBMicro_000204 [O-][N+](=O)c1ccc(NC(=O)CCCOc2ccc(Cl)cc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K07 compound treatment 633026.0 404000.0 0.83 599693.0 375000.0 0.81 1.1635 0.9999 1923347 CBMicro_000205 Cc1ccc(cc1N2C(=O)C=CC2=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K08 compound treatment 644728.0 416000.0 0.86 603439.0 378000.0 0.82 1.1863 0.9997 1923348 CBMicro_000206 COCCNC(=O)C(=O)NCCc1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K09 compound treatment 695425.0 467000.0 0.96 631829.0 407000.0 0.88 1.3038 0.999 1923349 CBMicro_000207 FC(F)(F)c1cc(NC(=O)C(c2ccccc2)c3ccccc3)ccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K10 compound treatment 652430.0 424000.0 0.87 622826.0 398000.0 0.86 1.2272 1.0 1197446 CBMicro_000208 Clc1ccc(OCC(=O)N(c2ccccc2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K11 compound treatment 673121.0 445000.0 0.92 619610.0 394000.0 0.85 1.2525 0.9994 1923350 CBMicro_000209 CN1CCN(CC1)C(=O)c2cccc([N+](=O)[O-])c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K12 compound treatment 660214.0 432000.0 0.89 604448.0 379000.0 0.82 1.2105 0.9992 1923351 CBMicro_000210 OCCN/C=C\1/c2ccccc2-c3ncccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K13 compound treatment 683103.0 454000.0 0.94 671660.0 447000.0 0.97 1.3468 0.9999 1923352 CBMicro_000211 COCCCNC(=O)/C(=C\C=C\c1ccccc1)/NC(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K14 compound treatment 674316.0 446000.0 0.92 652403.0 427000.0 0.92 1.3045 1.0 1923353 CBMicro_000212 OC1(CC(=O)c2cc(Cl)ccc2O1)C(F)(F)C(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K15 compound treatment 710272.0 482000.0 0.99 651070.0 426000.0 0.92 1.3549 0.9993 1923354 CBMicro_000213 CCOC(=O)C1(CC1)P(=O)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K16 compound treatment 667225.0 439000.0 0.91 630458.0 405000.0 0.88 1.2605 0.9999 1923355 CBMicro_000214 COc1ccccc1N2C(=O)/C(=C/c3cccc(Cl)c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K17 compound treatment 702604.0 474000.0 0.98 652642.0 427000.0 0.93 1.3461 0.9996 1923356 CBMicro_000215 CC/1=NN(C(=S)\C1=C\Nc2c(C)cc(C)cc2C)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K18 compound treatment 652007.0 423000.0 0.87 592485.0 367000.0 0.8 1.1802 0.9989 1923357 CBMicro_000216 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K19 compound treatment 694768.0 466000.0 0.96 616716.0 392000.0 0.85 1.2797 0.998 1923358 CBMicro_000217 CC(=O)c1cccc(NC(=O)/C=C/c2ccccc2Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K20 compound treatment 667747.0 439000.0 0.91 605856.0 381000.0 0.82 1.2236 0.9989 1923359 CBMicro_000218 OC(=O)c1ccccc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K21 compound treatment 690701.0 462000.0 0.95 629660.0 405000.0 0.88 1.2936 0.9991 1923360 CBMicro_000219 COc1ccc(cc1)N(CC(=O)Nc2cc(OC)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K22 compound treatment 644909.0 416000.0 0.86 593742.0 369000.0 0.8 1.1718 0.9993 1153062 CBMicro_000220 COC(=O)c1ccc(NS(=O)(=O)c2ccc(OC)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K23 mock treatment 642779.0 414000.0 0.85 603416.0 378000.0 0.82 1.1835 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 K24 mock treatment 258608.0 30000.0 0.06 291196.0 66000.0 0.14 0.1448 0.9299 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L01 mock treatment 14492.0 -214000.0 -0.44 11152.0 -214000.0 -0.46 -0.6401 -0.9997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L02 mock treatment 14733.0 -214000.0 -0.44 13477.0 -212000.0 -0.46 -0.6362 -0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L03 compound treatment 628172.0 400000.0 0.82 586393.0 361000.0 0.78 1.1361 0.9996 1923361 CBMicro_000221 CC(C)CNC(=O)C(=O)Nc1cccc(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L04 compound treatment 621530.0 393000.0 0.81 574962.0 350000.0 0.76 1.1089 0.9994 1923362 CBMicro_000222 O=C(Nc1ccc2ccccc2c1)c3ccc4C(=O)N(N5C(=O)c6ccccc6C5=O)C(=O)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L05 compound treatment 635662.0 407000.0 0.84 603635.0 378000.0 0.82 1.1734 0.9999 1923363 CBMicro_000223 COc1cc(C=O)ccc1Oc2nc(Nc3ccc(F)cc3F)nc(n2)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L06 compound treatment 599120.0 371000.0 0.76 581114.0 356000.0 0.77 1.0856 1.0 1151262 CBMicro_000224 Clc1ccc(Br)cc1C(=O)Nc2ccc-3c(Cc4ccccc43)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L07 compound treatment 717288.0 489000.0 1.01 601056.0 376000.0 0.81 1.2886 0.9943 1923364 CBMicro_000225 [O-][N+](=O)c1ccc(NCCCN2CCOCC2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L08 compound treatment 637990.0 409000.0 0.85 657905.0 433000.0 0.94 1.2599 0.9987 1923365 CBMicro_000226 Cc1c(Cl)cccc1c2ccc(C=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L09 compound treatment 647175.0 419000.0 0.86 626814.0 402000.0 0.87 1.2257 1.0 1923366 CBMicro_000227 CNC(=O)C(=O)Nc1ccc(OC)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L10 compound treatment 632595.0 404000.0 0.83 610439.0 385000.0 0.83 1.1793 1.0 1923367 CBMicro_000228 Cc1ccc(cc1)C(=O)NCCNc2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L11 compound treatment 666479.0 438000.0 0.9 658525.0 433000.0 0.94 1.3024 0.9998 1923368 CBMicro_000229 CC(C)(C)C1(O)CC(=NO1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L12 compound treatment 644302.0 416000.0 0.86 639838.0 415000.0 0.9 1.2414 0.9997 1250050 CBMicro_000230 Cc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L13 compound treatment 684941.0 456000.0 0.94 633292.0 408000.0 0.88 1.2907 0.9995 1461919 CBMicro_000231 Clc1ccc(NC(=O)N2CCN(CC2)c3ccccc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L14 compound treatment 664117.0 436000.0 0.9 640501.0 415000.0 0.9 1.2714 1.0 1923369 CBMicro_000232 FC(F)(F)c1ccc(Cl)c(c1)N2C(=O)C3C4C=CC(C3C2=O)C54CC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L15 compound treatment 675904.0 447000.0 0.92 674241.0 449000.0 0.97 1.3402 0.9997 1923370 CBMicro_000233 CC(=O)c1cccc(c1)N2C(=O)C3C(C2=O)C4(C)c5ccccc5C3(C)c6ccccc64 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L16 compound treatment 651254.0 423000.0 0.87 635771.0 411000.0 0.89 1.2453 1.0 1461270 CBMicro_000234 COc1ccc(cc1OC)S(=O)(=O)Nc2ccc(C)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L17 compound treatment 677393.0 449000.0 0.93 665009.0 440000.0 0.95 1.3282 0.9999 1337447 CBMicro_000235 Cc1ccc(C)c(NC(=O)c2cc3ccccc3oc2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L18 compound treatment 649575.0 421000.0 0.87 644815.0 420000.0 0.91 1.2567 0.9998 1353601 CBMicro_000236 Cc1c(NC(=O)c2ccc(Cl)c(Cl)c2)c(=O)n(c3ccccc3)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L19 compound treatment 655621.0 427000.0 0.88 659267.0 434000.0 0.94 1.2877 0.9995 1923371 CBMicro_000237 COc1ccc(NC(=O)CCN2C(=O)/C(=C/c3ccc(F)cc3)/SC2=S)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L20 compound treatment 660182.0 432000.0 0.89 620000.0 395000.0 0.85 1.2342 0.9998 1122649 CBMicro_000238 Clc1ccc(OCC(=O)Nc2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L21 compound treatment 657632.0 429000.0 0.89 656616.0 431000.0 0.93 1.2866 0.9996 1923372 CBMicro_000239 Cc1ccccc1N/C(=N\OCc2ccccc2)/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L22 compound treatment 641754.0 413000.0 0.85 666120.0 441000.0 0.95 1.2779 0.9984 1491422 CBMicro_000240 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CCCC3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L23 mock treatment 627633.0 399000.0 0.82 613790.0 389000.0 0.84 1.1772 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 L24 mock treatment 250744.0 22100.0 0.05 209936.0 -15200.0 -0.03 0.009 0.1599 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M01 mock treatment 14974.0 -214000.0 -0.44 15707.0 -209000.0 -0.45 -0.6324 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M02 mock treatment 14628.0 -214000.0 -0.44 14251.0 -211000.0 -0.46 -0.6351 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M03 compound treatment 653008.0 424000.0 0.88 605738.0 381000.0 0.82 1.2019 0.9995 1923373 CBMicro_000241 COC(=O)c1ccccc1NC(=O)/C=C/c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M04 compound treatment 618506.0 390000.0 0.8 565095.0 340000.0 0.74 1.0894 0.999 1923374 CBMicro_000242 [O-][N+](=O)c1ccccc1C(=O)Nc2ccccc2F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M05 compound treatment 661286.0 433000.0 0.89 587263.0 362000.0 0.78 1.1857 0.9979 1428998 CBMicro_000243 CC(=O)Nc1ccc(NC(=O)N2CCOCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M06 compound treatment 630109.0 401000.0 0.83 565999.0 341000.0 0.74 1.1077 0.9983 1205740 CBMicro_000244 CCc1cccc(C)c1NS(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M07 compound treatment 655412.0 427000.0 0.88 598377.0 373000.0 0.81 1.1942 0.9991 1378251 CBMicro_000245 COc1ccc(cc1)C(=O)NC(Cc2cnc[nH]2)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M08 compound treatment 651958.0 423000.0 0.87 576218.0 351000.0 0.76 1.1552 0.9976 1923375 CBMicro_000246 OCCCNC(=O)C(=O)NCc1ccc(Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M09 compound treatment 661359.0 433000.0 0.89 612792.0 388000.0 0.84 1.2249 0.9995 1923376 CBMicro_000247 COc1ccc(C)cc1NS(=O)(=O)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M10 compound treatment 655309.0 427000.0 0.88 609699.0 385000.0 0.83 1.2114 0.9996 1075917 CBMicro_000248 COc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M11 compound treatment 691225.0 463000.0 0.95 620742.0 396000.0 0.86 1.2807 0.9985 1923377 CBMicro_000249 [O-][N+](=O)c1ccc(C(=O)N(Cc2ccccc2)c3ccccn3)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M12 compound treatment 648724.0 420000.0 0.87 609525.0 384000.0 0.83 1.2015 0.9998 1704788 CBMicro_000250 COc1ccc2nc(NC(=O)c3ccc(OC)c(Br)c3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M13 compound treatment 698884.0 470000.0 0.97 646824.0 422000.0 0.91 1.3318 0.9995 1923378 CBMicro_000251 CC(=O)/C=C(\N)/NC(=O)c1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M14 compound treatment 674797.0 446000.0 0.92 636131.0 411000.0 0.89 1.2803 0.9998 1310984 CBMicro_000252 CCOc1ccc(NC2(C(=O)c3ccccc3C2=O)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M15 compound treatment 683180.0 455000.0 0.94 635327.0 410000.0 0.89 1.2913 0.9996 1923379 CBMicro_000253 OC(=O)CC(C(=O)O)P(=O)(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M16 compound treatment 657189.0 429000.0 0.88 606877.0 382000.0 0.83 1.2098 0.9994 1923380 CBMicro_000254 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cc(ccc2C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M17 compound treatment 682857.0 454000.0 0.94 636756.0 412000.0 0.89 1.293 0.9997 1923381 CBMicro_000255 O=P(C1CCOCC1)(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M18 compound treatment 680791.0 452000.0 0.93 694358.0 469000.0 1.02 1.3781 0.9991 1923382 CBMicro_000256 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M19 compound treatment 672461.0 444000.0 0.92 626269.0 401000.0 0.87 1.2618 0.9996 1923383 CBMicro_000257 CCOc1ccccc1NC(=O)/C=C/c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M20 compound treatment 639978.0 411000.0 0.85 605002.0 380000.0 0.82 1.1818 0.9999 1716346 CBMicro_000258 Fc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M21 compound treatment 683572.0 455000.0 0.94 628348.0 403000.0 0.87 1.2812 0.9993 1923384 CBMicro_000259 Cc1cc(C)c(cc1[N+](=O)[O-])c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M22 compound treatment 635687.0 407000.0 0.84 590856.0 366000.0 0.79 1.1539 0.9996 1923385 CBMicro_000260 Cc1ccc2oc(cc(=O)c2c1)C(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M23 mock treatment 680142.0 452000.0 0.93 606724.0 382000.0 0.83 1.2431 0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 M24 mock treatment 379577.0 151000.0 0.31 318202.0 93000.0 0.2 0.3628 0.9777 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N01 mock treatment 15676.0 -213000.0 -0.44 15623.0 -210000.0 -0.45 -0.6315 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N02 mock treatment 14597.0 -214000.0 -0.44 15257.0 -210000.0 -0.45 -0.6336 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N03 compound treatment 613158.0 385000.0 0.79 575247.0 350000.0 0.76 1.0971 0.9997 1477274 CBMicro_000261 Cc1cccc(N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cccc(O)c4)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N04 compound treatment 600036.0 371000.0 0.77 577149.0 352000.0 0.76 1.0809 1.0 1741849 CBMicro_000262 Cc1onc(c1C(=O)Nc2ccc(C)cc2C)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N05 compound treatment 633654.0 405000.0 0.84 614564.0 389000.0 0.84 1.1872 1.0 1923386 CBMicro_000263 Cc1cccc(c1)C2OC3(C(c4ccc(Br)cc4)C25C(=O)c6ccccc6C5=O)C(=O)c7ccccc7C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N06 compound treatment 609876.0 381000.0 0.79 579039.0 354000.0 0.77 1.0981 0.9999 1923387 CBMicro_000264 Clc1ccc(cc1)C2SCC(=O)N2c3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N07 compound treatment 624409.0 396000.0 0.82 602309.0 377000.0 0.82 1.1549 1.0 1923388 CBMicro_000265 CCC1CCCCN1C(=O)c2cnn3c(cc(nc23)c4ccc(C)cc4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N08 compound treatment 613474.0 385000.0 0.79 594199.0 369000.0 0.8 1.1266 1.0 1661907 CBMicro_000266 CCC(=O)Nc1cccc(NC(=O)c2ccc(Cl)c(Cl)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N09 compound treatment 635231.0 407000.0 0.84 607909.0 383000.0 0.83 1.1793 1.0 1923389 CBMicro_000267 COC(=O)c1cccc(NC(=O)/C=C/c2ccccc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N10 compound treatment 1106729.0 878000.0 1.81 1090324.0 865000.0 1.87 2.6059 0.9999 1923390 CBMicro_000268 Fc1ccc(cc1Cl)c2ccc(/C=C\3/NC(=S)NC3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N11 compound treatment 675837.0 447000.0 0.92 619130.0 394000.0 0.85 1.2558 0.9992 1923391 CBMicro_000269 COc1ccc2oc(cc(=O)c2c1)C(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N12 compound treatment 616357.0 388000.0 0.8 625717.0 401000.0 0.87 1.179 0.9992 1923392 CBMicro_000270 COc1ccc(/C=C/2\SC(=O)N(CC(=O)NC(C)(C)C)C2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N13 compound treatment 634563.0 406000.0 0.84 624199.0 399000.0 0.86 1.2033 0.9999 1535664 CBMicro_000271 O=C(NCc1ccc2OCOc2c1)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N14 compound treatment 629029.0 400000.0 0.83 612874.0 388000.0 0.84 1.1779 1.0 1923393 CBMicro_000272 [O-][N+](=O)[N-][n+]1cnn(CC(=O)N2CCN(CC2)C(=O)Cn3c[n+]([N-][N+](=O)[O-])cn3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N15 compound treatment 635482.0 407000.0 0.84 650338.0 425000.0 0.92 1.2446 0.999 1923394 CBMicro_000273 [O-][N+](=O)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N16 compound treatment 625052.0 396000.0 0.82 606617.0 381000.0 0.83 1.1625 1.0 1923395 CBMicro_000274 [O-][N+](=O)c1cc(Cl)ccc1NCCNC(=O)c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N17 compound treatment 617007.0 388000.0 0.8 614795.0 390000.0 0.84 1.1633 0.9997 1923396 CBMicro_000275 Cc1cc(NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])ccc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N18 compound treatment 623188.0 395000.0 0.81 673931.0 449000.0 0.97 1.2628 0.9962 1923397 CBMicro_000276 CC(=O)Nc1ccc(NC2=C(Cl)C(=O)c3c2c(Cl)c(Cl)c(Cl)c3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N19 compound treatment 657238.0 429000.0 0.88 674637.0 449000.0 0.97 1.3136 0.9989 1923398 CBMicro_000277 COC(=O)c1ccccc1NC(=O)/C=C/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N20 compound treatment 610578.0 382000.0 0.79 616165.0 391000.0 0.85 1.156 0.9994 1923399 CBMicro_000278 CC1CCc2c(C1)sc3nc([nH]c(=O)c23)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N21 compound treatment 634871.0 406000.0 0.84 631176.0 406000.0 0.88 1.2144 0.9997 1172800 CBMicro_000279 CC(C)C(=O)N1C(C)CC(N(C(=O)c2ccc(F)cc2)c3ccccc3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N22 compound treatment 618586.0 390000.0 0.81 604032.0 379000.0 0.82 1.1491 1.0 1262142 CBMicro_000280 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N23 mock treatment 614356.0 386000.0 0.8 606515.0 381000.0 0.83 1.1467 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 N24 mock treatment 377283.0 149000.0 0.31 364131.0 139000.0 0.3 0.4297 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O01 mock treatment 15236.0 -213000.0 -0.44 15068.0 -210000.0 -0.45 -0.633 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O02 mock treatment 14723.0 -214000.0 -0.44 14534.0 -211000.0 -0.46 -0.6346 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O03 compound treatment 617948.0 389000.0 0.8 561706.0 337000.0 0.73 1.0834 0.9988 1923400 CBMicro_000281 Cc1ccc(NC(=O)/C=C/c2ccccc2Cl)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O04 compound treatment 585131.0 357000.0 0.74 546554.0 321000.0 0.7 1.0123 0.9996 1562705 CBMicro_000282 Cc1nc2ccccc2c(=O)n1c3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O05 compound treatment 623034.0 394000.0 0.81 580992.0 356000.0 0.77 1.1203 0.9996 1246134 CBMicro_000283 CCN(CC)C(=O)c1ccccc1NC(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O06 compound treatment 666713.0 438000.0 0.9 546007.0 321000.0 0.69 1.1305 0.9915 1923401 CBMicro_000284 COc1ccc(cc1)C(=O)Nc2ccc(cc2C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O07 compound treatment 641527.0 413000.0 0.85 586567.0 361000.0 0.78 1.1558 0.9991 1289235 CBMicro_000285 Nc1ccc2oc(nc2c1)c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O08 compound treatment 607943.0 379000.0 0.78 563971.0 339000.0 0.73 1.0722 0.9995 1923402 CBMicro_000286 CC(=O)c1cccc(NC(=O)Nc2cccc(Cl)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O09 compound treatment 622958.0 394000.0 0.81 573864.0 349000.0 0.75 1.1093 0.9993 1923403 CBMicro_000287 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O10 compound treatment 615681.0 387000.0 0.8 567988.0 343000.0 0.74 1.0897 0.9993 1081907 CBMicro_000288 Clc1ccc(OCC(=O)Nc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O11 compound treatment 636081.0 407000.0 0.84 588804.0 364000.0 0.79 1.1513 0.9994 1404309 CBMicro_000289 Fc1ccc(cc1)S(=O)(=O)NCc2ccncc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O12 compound treatment 709197.0 481000.0 0.99 613127.0 388000.0 0.84 1.2953 0.9966 1537054 CBMicro_000290 Cc1ccc(NC2(C(=O)c3ccccc3C2=O)c4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O13 compound treatment 633924.0 405000.0 0.84 604134.0 379000.0 0.82 1.1716 1.0 1923404 CBMicro_000291 CCCCOC(=O)c1ccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O14 compound treatment 620076.0 391000.0 0.81 583215.0 358000.0 0.77 1.1194 0.9998 1011843 CBMicro_000292 CCOC(=O)C(=O)C1C(=O)C(C)C(=O)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O15 compound treatment 639622.0 411000.0 0.85 609384.0 384000.0 0.83 1.188 0.9999 1608210 CBMicro_000293 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4ccco4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O16 compound treatment 637430.0 409000.0 0.84 583775.0 359000.0 0.78 1.1456 0.9991 1725662 CBMicro_000294 OC(=O)CCC(=O)Nc1ccccc1c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O17 compound treatment 657730.0 429000.0 0.89 606568.0 381000.0 0.83 1.2101 0.9994 1923405 CBMicro_000295 COc1ccc(NC(=O)C(c2ccccc2)c3ccccc3)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O18 compound treatment 624453.0 396000.0 0.82 587746.0 363000.0 0.78 1.1327 0.9998 1923406 CBMicro_000296 CCn1c2ccccc2c3cc(CNCCc4ccc(OC)c(OC)c4)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O19 compound treatment 643130.0 415000.0 0.86 609880.0 385000.0 0.83 1.1939 0.9999 1923407 CBMicro_000297 Cn1cnnc1SCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O20 compound treatment 609314.0 381000.0 0.79 588744.0 364000.0 0.79 1.1122 1.0 1367245 CBMicro_000298 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O21 compound treatment 630299.0 402000.0 0.83 598098.0 373000.0 0.81 1.1571 0.9999 1923408 CBMicro_000299 COc1cccc(/C=C\2/SC(=N)NC2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O22 compound treatment 824069.0 595000.0 1.23 566235.0 341000.0 0.74 1.3912 0.9702 1923409 CBMicro_000300 COc1ccc(NC(=O)/C=C/c2ccccc2Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O23 mock treatment 623231.0 395000.0 0.81 581832.0 357000.0 0.77 1.1219 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 O24 mock treatment 250074.0 21500.0 0.04 181337.0 -43800.0 -0.09 -0.0357 -0.3414 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P01 mock treatment 15100.0 -214000.0 -0.44 15393.0 -210000.0 -0.45 -0.6327 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P02 mock treatment 15152.0 -213000.0 -0.44 15686.0 -209000.0 -0.45 -0.6322 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P03 compound treatment 607347.0 379000.0 0.78 565303.0 340000.0 0.74 1.0734 0.9995 1923410 CBMicro_000301 ClC(Cl)(Cl)C(=O)CC(=O)/C=C/c1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P04 compound treatment 571428.0 343000.0 0.71 546864.0 322000.0 0.7 0.9928 1.0 1686764 CBMicro_000302 Ic1ccc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P05 compound treatment 560522.0 332000.0 0.69 556472.0 331000.0 0.72 0.9915 0.9997 1923411 CBMicro_000303 CCC(=O)/N=C(\N)/Nc1nc(C)c2cc(C)cc(C)c2n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P06 compound treatment 578717.0 350000.0 0.72 573445.0 348000.0 0.75 1.0441 0.9998 1730991 CBMicro_000304 Clc1ccc(cc1NC(=O)c2cc(I)ccc2Cl)c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P07 compound treatment 579979.0 351000.0 0.73 557395.0 332000.0 0.72 1.0214 1.0 1923412 CBMicro_000305 COc1ccc(N2C(=O)C3C4C=CC(C3C2=O)C54CC5)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P08 compound treatment 584008.0 355000.0 0.73 556415.0 331000.0 0.72 1.0257 0.9999 1923413 CBMicro_000306 CCC(=O)Nc1cccc(NC(=O)c2ccc(cc2)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P09 compound treatment 589913.0 361000.0 0.75 552791.0 328000.0 0.71 1.0288 0.9997 1148467 CBMicro_000307 COc1ccc(C)cc1NC(=O)c2cccnc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P10 compound treatment 601337.0 373000.0 0.77 564500.0 339000.0 0.73 1.0634 0.9997 1923414 CBMicro_000308 [O-][N+](=O)[N-][n+]1cnn(CC(=O)Nc2ccc(cc2)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P11 compound treatment 586375.0 358000.0 0.74 560845.0 336000.0 0.73 1.036 1.0 1669763 CBMicro_000309 Clc1ccc(OCC(=O)Nc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P12 compound treatment 595780.0 367000.0 0.76 566704.0 342000.0 0.74 1.0587 0.9999 1923415 CBMicro_000310 Brc1ccc(OCc2ccccc2)c(/C=C/3\SC(=N)NC3=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P13 compound treatment 585798.0 357000.0 0.74 568781.0 344000.0 0.74 1.0473 1.0 1582596 CBMicro_000311 Cc1cn(cn1)S(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P14 compound treatment 600454.0 372000.0 0.77 589635.0 364000.0 0.79 1.1006 0.9999 1923416 CBMicro_000312 [O-][N+](=O)[N-][n+]1cnn(CC(=O)Nc2ccc(NC(=O)Cn3c[n+]([N-][N+](=O)[O-])cn3)cc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P15 compound treatment 582292.0 354000.0 0.73 578932.0 354000.0 0.77 1.0577 0.9997 1683237 CBMicro_000313 CC(C)CC(=O)N1c2ccc(C)cc2-c3c(ssc3=S)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P16 compound treatment 599082.0 370000.0 0.76 552149.0 327000.0 0.71 1.0412 0.9993 1923417 CBMicro_000314 Oc1cc(ccc1NC(=S)Nc2ccccc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P17 compound treatment 601352.0 373000.0 0.77 589013.0 364000.0 0.79 1.1009 0.9999 1923418 CBMicro_000315 Cc1cc(Br)ccc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P18 compound treatment 596723.0 368000.0 0.76 578640.0 353000.0 0.77 1.0783 1.0 1530214 CBMicro_000316 NC(=O)c1cc(NC(=O)C(c2ccccc2)c3ccccc3)ccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P19 compound treatment 608173.0 380000.0 0.78 587915.0 363000.0 0.79 1.1092 1.0 1923419 CBMicro_000317 FC(F)(F)C(=O)CC(=O)/C=C/c1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P20 compound treatment 594158.0 366000.0 0.75 582205.0 357000.0 0.77 1.08 0.9999 1520687 CBMicro_000318 Clc1ccc(NC(=O)C2CCC(=O)N2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P21 compound treatment 588194.0 360000.0 0.74 577100.0 352000.0 0.76 1.0635 0.9999 1923420 CBMicro_000319 Oc1ccc(cc1)N2C(=O)/C(=C/c3ccccc3Cl)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P22 compound treatment 588165.0 360000.0 0.74 576935.0 352000.0 0.76 1.0632 0.9999 1923421 CBMicro_000320 Clc1cccc(Cl)c1/C=C/C(=O)c2ccc3OCCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P23 mock treatment 575102.0 346000.0 0.72 568235.0 343000.0 0.74 1.0308 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.686 P24 mock treatment 402761.0 174000.0 0.36 422333.0 197000.0 0.43 0.556 0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A01 mock treatment 16032.0 -206000.0 -0.43 17215.0 -215000.0 -0.46 -0.6297 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A02 mock treatment 17194.0 -205000.0 -0.42 17362.0 -214000.0 -0.46 -0.6278 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A03 compound treatment 608212.0 386000.0 0.8 542295.0 310000.0 0.67 1.0383 0.9964 1923422 CBMicro_000321 COc1ccc(cc1OC)C(=O)/C=C/Nc2ccc(cc2)S(=O)(=O)NC(=N)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A04 compound treatment 583267.0 361000.0 0.74 542243.0 310000.0 0.67 1.0018 0.9987 1923423 CBMicro_000322 Cc1ccccc1C(=O)Nc2cccc(NC(=O)c3ccccc3[N+](=O)[O-])c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A05 compound treatment 593442.0 371000.0 0.77 546561.0 315000.0 0.68 1.0233 0.9983 1923424 CBMicro_000323 CC(C)CN1C(=O)c2ccc(Oc3ccc(cc3)[N+](=O)[O-])cc2C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A06 compound treatment 619885.0 397000.0 0.82 558747.0 327000.0 0.71 1.0805 0.9973 1365184 CBMicro_000324 CC1=C(C(NC(=O)N1)c2cccc(O)c2)C(=O)OCc3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A07 compound treatment 628950.0 407000.0 0.84 579255.0 347000.0 0.75 1.1252 0.9985 1923425 CBMicro_000325 CC(=O)c1ccc(NC(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A08 compound treatment 638678.0 416000.0 0.86 579840.0 348000.0 0.75 1.1402 0.9978 1923426 CBMicro_000326 COc1ccccc1OCCNc2cc(Cl)ccc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A09 compound treatment 619562.0 397000.0 0.82 598377.0 367000.0 0.79 1.1407 0.9999 1233749 CBMicro_000327 CCc1ccc(OCC(=O)Nc2ccc(F)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A10 compound treatment 648921.0 427000.0 0.88 590126.0 358000.0 0.78 1.1709 0.998 1283032 CBMicro_000328 O=C(NCc1ccccn1)c2ccccc2Oc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A11 compound treatment 646525.0 424000.0 0.88 586521.0 355000.0 0.77 1.1619 0.9979 1923427 CBMicro_000329 Clc1ccc(cc1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A12 compound treatment 600735.0 378000.0 0.78 609133.0 377000.0 0.82 1.1297 0.9998 1923428 CBMicro_000330 Cc1nn(CC(=O)Nc2sc(C)c(C)c2C(=O)N)c(C)c1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A13 compound treatment 630648.0 408000.0 0.84 584305.0 352000.0 0.76 1.1354 0.9988 1923429 CBMicro_000331 COc1ccc(OC)c(/C=C/C(=O)Nc2cccc(Br)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A14 compound treatment 640437.0 418000.0 0.86 600525.0 369000.0 0.8 1.1745 0.9992 1186155 CBMicro_000332 COc1ccc(NS(=O)(=O)c2ccc(OC)c(OC)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A15 compound treatment 617414.0 395000.0 0.82 601659.0 370000.0 0.8 1.1426 1.0 1923430 CBMicro_000333 Cc1cc(I)ccc1NC(=O)/C=C/c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A16 compound treatment 644070.0 422000.0 0.87 619471.0 388000.0 0.84 1.2088 0.9998 1689572 CBMicro_000334 Clc1ccccc1N2CCN(CC2)C(=O)CN3C(=O)c4ccccc4C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A17 compound treatment 631473.0 409000.0 0.84 615308.0 383000.0 0.83 1.184 1.0 1923431 CBMicro_000335 COc1ccc(cc1OC)C(=O)/C=C/Nc2ccccc2I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A18 compound treatment 619690.0 397000.0 0.82 612928.0 381000.0 0.82 1.1632 1.0 1923432 CBMicro_000336 C(C#CCn1c2ccccc2c3ccccc13)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A19 compound treatment 691995.0 470000.0 0.97 598125.0 366000.0 0.79 1.2461 0.995 1923433 CBMicro_000337 COc1ccc(cc1OC)C(=O)NC2=NCCS2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A20 compound treatment 592881.0 370000.0 0.76 581653.0 350000.0 0.76 1.0762 1.0 1692766 CBMicro_000338 O=C(N1CCSCC1)c2cnn3c(cc(nc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A21 compound treatment 590219.0 368000.0 0.76 557530.0 326000.0 0.7 1.0354 0.9993 1145282 CBMicro_000339 CCOC(=O)c1ccccc1NC(=O)c2cc(OC)cc(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A22 compound treatment 582717.0 360000.0 0.74 548406.0 317000.0 0.69 1.0105 0.9992 1117735 CBMicro_000340 CCOc1ccc(c2ccccc12)S(=O)(=O)Nc3ccccn3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A23 mock treatment 548667.0 326000.0 0.67 543691.0 312000.0 0.67 0.9535 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 A24 mock treatment 284462.0 62100.0 0.13 252660.0 20800.0 0.05 0.1225 0.9017 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B01 mock treatment 16691.0 -206000.0 -0.42 16786.0 -215000.0 -0.47 -0.6294 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B02 mock treatment 16827.0 -206000.0 -0.42 17864.0 -214000.0 -0.46 -0.6275 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B03 compound treatment 639168.0 417000.0 0.86 636236.0 404000.0 0.88 1.2273 1.0 1149757 CBMicro_000341 Fc1ccccc1NC(=O)c2ccc3nccnc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B04 compound treatment 639647.0 417000.0 0.86 610100.0 378000.0 0.82 1.188 0.9997 1923434 CBMicro_000342 FC(F)(F)c1ccc(Cl)c(NC(=O)c2nc3nc(cc(n3n2)C(F)(F)F)c4ccccc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B05 compound treatment 671529.0 449000.0 0.93 648951.0 417000.0 0.9 1.294 0.9999 1923435 CBMicro_000343 Cn1ccnc1c2ccc(cc2)c3nccn3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B06 compound treatment 659898.0 438000.0 0.9 627727.0 396000.0 0.86 1.2445 0.9997 1923436 CBMicro_000344 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccccc3Oc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B07 compound treatment 686065.0 464000.0 0.96 686383.0 455000.0 0.98 1.3725 0.9999 1386203 CBMicro_000345 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B08 compound treatment 675255.0 453000.0 0.93 659303.0 427000.0 0.93 1.3153 1.0 1218193 CBMicro_000346 O=C(NCCN1CCCCC1)c2cc3ccccc3o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B09 compound treatment 842605.0 620000.0 1.28 831102.0 599000.0 1.3 1.8225 1.0 1923437 CBMicro_000347 COc1ccc(cc1)c2nc(NC(=O)c3ccco3)sc2c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B10 compound treatment 726232.0 504000.0 1.04 667077.0 435000.0 0.94 1.4016 0.9988 1254668 CBMicro_000348 CCOc1cc(ccc1OC(=O)Cc2ccccc2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B11 compound treatment 703177.0 481000.0 0.99 691532.0 460000.0 0.99 1.4053 1.0 1500919 CBMicro_000349 CCOc1cc(cc(OCC)c1OCC)C(=O)NC(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B12 compound treatment 649065.0 427000.0 0.88 671613.0 440000.0 0.95 1.2959 0.9992 1185186 CBMicro_000350 O=C1NC(Nc2ccccc12)c3ccccc3OCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B13 compound treatment 707294.0 485000.0 1.0 706362.0 475000.0 1.03 1.434 0.9999 1434033 CBMicro_000351 COc1ccccc1OCC(=O)Nc2ccc3OCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B14 compound treatment 981849.0 759000.0 1.57 841340.0 610000.0 1.32 2.0414 0.9963 1923438 CBMicro_000352 COc1ccc(cc1)c2nc(NC(=O)c3ccccc3F)sc2c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B15 compound treatment 710172.0 488000.0 1.01 758510.0 527000.0 1.14 1.5181 0.9981 1740104 CBMicro_000353 COC(=O)c1sccc1NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B16 compound treatment 721508.0 499000.0 1.03 672221.0 440000.0 0.95 1.4025 0.9992 1923439 CBMicro_000354 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)Nc3cccnc3)C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B17 compound treatment 654049.0 432000.0 0.89 692664.0 461000.0 1.0 1.3354 0.9984 1923440 CBMicro_000355 CC1=NN(C(=O)c2ccccc2)C(C)(O)C1(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B18 compound treatment 655683.0 433000.0 0.89 664240.0 432000.0 0.94 1.2942 0.9997 1706376 CBMicro_000356 CN(Cc1ccccc1)C(=O)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B19 compound treatment 675950.0 454000.0 0.94 675307.0 443000.0 0.96 1.3408 0.9999 1923441 CBMicro_000357 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2cc(OC)ccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B20 compound treatment 622644.0 400000.0 0.83 641250.0 409000.0 0.89 1.2108 0.9994 1244374 CBMicro_000358 COc1ccc(cc1)C(=O)N(C2CC(C)Nc3ccccc23)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B21 compound treatment 635126.0 413000.0 0.85 667110.0 435000.0 0.94 1.2686 0.9987 1688339 CBMicro_000359 Clc1ccc(C(=O)Nc2ccc(cc2Cl)N3C(=O)c4ccccc4C3=O)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B22 compound treatment 600503.0 378000.0 0.78 605696.0 374000.0 0.81 1.1241 0.9998 1923442 CBMicro_000360 CC1CN(CCN1C(=O)c2ccc(C)o2)c3ccc(cc3Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B23 mock treatment 580611.0 358000.0 0.74 619479.0 388000.0 0.84 1.1162 0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 B24 mock treatment 217810.0 -4590.0 -0.01 209391.0 -22400.0 -0.05 -0.041 -0.8294 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C01 mock treatment 16796.0 -206000.0 -0.42 16094.0 -216000.0 -0.47 -0.6303 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C02 mock treatment 16262.0 -206000.0 -0.43 16953.0 -215000.0 -0.47 -0.6298 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C03 compound treatment 657108.0 435000.0 0.9 630228.0 398000.0 0.86 1.2443 0.9998 1923443 CBMicro_000361 Cc1cc(C)c2oc(nc2c1)c3ccc(NC(=O)c4ccccc4[N+](=O)[O-])cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C04 compound treatment 748718.0 526000.0 1.09 750768.0 519000.0 1.12 1.5625 0.9999 1923444 CBMicro_000362 Brc1ccc(NC(=O)/C=C/c2ccco2)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C05 compound treatment 665927.0 444000.0 0.92 646980.0 415000.0 0.9 1.2828 1.0 1923445 CBMicro_000363 COc1cccc(CNCCc2ccccc2F)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C06 compound treatment 653207.0 431000.0 0.89 616771.0 385000.0 0.83 1.218 0.9995 1923446 CBMicro_000364 [O-][N+](=O)c1ccccc1NCCNC(=O)c2ccc(Br)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C07 compound treatment 697671.0 475000.0 0.98 675444.0 444000.0 0.96 1.3727 0.9999 1923447 CBMicro_000365 CCOC(=O)N(CC(=O)OC)CP(=O)(OCC)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C08 compound treatment 713554.0 491000.0 1.01 686431.0 455000.0 0.98 1.4127 0.9999 1417852 CBMicro_000366 COc1cc(cc(Cl)c1O)C2NC(=O)NC(=C2C(=O)OCCc3ccccc3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C09 compound treatment 705557.0 483000.0 1.0 686114.0 454000.0 0.98 1.4005 1.0 1144322 CBMicro_000367 CCC(=O)Nc1ccc(NC(=O)c2ccc(Br)o2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C10 compound treatment 706212.0 484000.0 1.0 677545.0 446000.0 0.96 1.3884 0.9998 1445684 CBMicro_000368 COc1ccc(CNC(=O)C2c3ccccc3Oc4ccccc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C11 compound treatment 716446.0 494000.0 1.02 705206.0 473000.0 1.02 1.4456 1.0 1181784 CBMicro_000369 OCCCC(=O)c1ccc2OCCOc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C12 compound treatment 697143.0 475000.0 0.98 678393.0 447000.0 0.97 1.3764 1.0 1495436 CBMicro_000370 O=C(NCc1ccco1)c2cnn3c(cc(nc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C13 compound treatment 725467.0 503000.0 1.04 705954.0 474000.0 1.03 1.4599 1.0 1923448 CBMicro_000371 C/C(=N\NC(=O)c1ccc(O)cc1)/Cn2nnc(n2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C14 compound treatment 701001.0 479000.0 0.99 685603.0 454000.0 0.98 1.3931 1.0 1923449 CBMicro_000372 CC1CCN(CC1)C(=O)c2ccc3nc4c5ccccc5c6ccccc6c4nc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C15 compound treatment 740122.0 518000.0 1.07 711167.0 479000.0 1.04 1.4893 0.9999 1923450 CBMicro_000373 C=CCOc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C16 compound treatment 708301.0 486000.0 1.0 682109.0 450000.0 0.97 1.3984 0.9999 1533708 CBMicro_000374 COc1ccc(NC(=O)c2ccc(cc2)N3C(=O)CCC3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C17 compound treatment 715125.0 493000.0 1.02 693395.0 462000.0 1.0 1.4256 1.0 1923451 CBMicro_000375 Brc1ccc(o1)C(=O)Nc2ccc3c(c2)oc4ccccc43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C18 compound treatment 660300.0 438000.0 0.9 650298.0 418000.0 0.91 1.2796 1.0 1585741 CBMicro_000376 Cc1cc(N2CCOCC2)c3n(C)c4ccccc4c3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C19 compound treatment 676947.0 455000.0 0.94 690345.0 459000.0 0.99 1.3652 0.9996 1382483 CBMicro_000377 CCOc1ccc2nc(NC(=O)c3cccc(Cl)c3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C20 compound treatment 621963.0 400000.0 0.82 660129.0 428000.0 0.93 1.2387 0.9983 1923452 CBMicro_000378 [O-][N+](=O)c1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)NCCc4ccccc4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C21 compound treatment 689207.0 467000.0 0.96 677659.0 446000.0 0.96 1.3637 1.0 1569137 CBMicro_000379 Cc1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C22 compound treatment 601551.0 379000.0 0.78 637193.0 405000.0 0.88 1.1738 0.9984 1923453 CBMicro_000380 COc1ccccc1/C=C\2/SC(=O)N(CNc3cccc(Cl)c3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C23 mock treatment 602930.0 381000.0 0.79 619921.0 388000.0 0.84 1.1494 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 C24 mock treatment 283154.0 60800.0 0.13 215486.0 -16300.0 -0.04 0.0637 0.4886 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D01 mock treatment 16691.0 -206000.0 -0.42 16283.0 -216000.0 -0.47 -0.6302 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D02 mock treatment 15916.0 -206000.0 -0.43 16807.0 -215000.0 -0.47 -0.6305 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D03 compound treatment 659831.0 437000.0 0.9 652275.0 420000.0 0.91 1.282 1.0 1923454 CBMicro_000381 COCCCN1C(=C(C(=O)OC)/C(=C/c2ccccc2O)/C1=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D04 compound treatment 649821.0 427000.0 0.88 659060.0 427000.0 0.92 1.2778 0.9997 1923455 CBMicro_000382 Clc1ccc(cc1Cl)c2ccc(/C=C\3/SC(=S)N(CC=C)C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D05 compound treatment 674015.0 452000.0 0.93 683902.0 452000.0 0.98 1.3511 0.9997 1923456 CBMicro_000383 Cc1c(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(Cl)cc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D06 compound treatment 675837.0 453000.0 0.94 678440.0 447000.0 0.97 1.3454 0.9999 1599491 CBMicro_000384 O=C(NCc1ccco1)C2c3ccccc3Oc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D07 compound treatment 706838.0 484000.0 1.0 689541.0 458000.0 0.99 1.4076 1.0 1923457 CBMicro_000385 CCCNC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D08 compound treatment 682355.0 460000.0 0.95 692539.0 461000.0 1.0 1.3765 0.9997 1923458 CBMicro_000386 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2cccc(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D09 compound treatment 725926.0 504000.0 1.04 715326.0 483000.0 1.05 1.475 1.0 1923459 CBMicro_000387 Cc1nn(CC(=O)Nc2ccc(Cl)cc2Cl)c(C)c1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D10 compound treatment 686778.0 464000.0 0.96 670191.0 438000.0 0.95 1.3487 1.0 1923460 CBMicro_000388 Cc1onc(c1C(=O)N2CCN(CC2)c3c(Cl)cccc3[N+](=O)[O-])c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D11 compound treatment 687840.0 465000.0 0.96 715920.0 484000.0 1.05 1.4203 0.9991 1923461 CBMicro_000389 COc1cc(ccc1OC(=O)c2ccc(cc2)[N+](=O)[O-])C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D12 compound treatment 703895.0 481000.0 0.99 701179.0 469000.0 1.02 1.4211 0.9999 1500636 CBMicro_000390 COc1ccc(cc1)N(CC(O)CN2C(=O)NC(C)(C)C2=O)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D13 compound treatment 709229.0 487000.0 1.0 715878.0 484000.0 1.05 1.4514 0.9998 1208980 CBMicro_000391 O=C(CSc1nc2ccccc2[nH]1)c3ccc(cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D14 compound treatment 703602.0 481000.0 0.99 731289.0 499000.0 1.08 1.4668 0.9991 1261835 CBMicro_000392 COc1ccc(NC(=O)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D15 compound treatment 700899.0 479000.0 0.99 740134.0 508000.0 1.1 1.4764 0.9986 1923462 CBMicro_000393 Clc1ccc(Cl)c(c1)C(=O)N2CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D16 compound treatment 725032.0 503000.0 1.04 719421.0 488000.0 1.06 1.4799 1.0 1923463 CBMicro_000394 CCCC(C)NS(=O)(=O)c1ccc(cc1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D17 compound treatment 718372.0 496000.0 1.02 726910.0 495000.0 1.07 1.4817 0.9997 1923464 CBMicro_000395 COc1cc(cc(OC)c1OC(=O)c2cccc(c2)[N+](=O)[O-])C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D18 compound treatment 712106.0 490000.0 1.01 727617.0 496000.0 1.07 1.4736 0.9996 1923465 CBMicro_000396 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(C)c(Cl)c3)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D19 compound treatment 665330.0 443000.0 0.91 704300.0 472000.0 1.02 1.3696 0.9984 1414250 CBMicro_000397 CCOc1ccc(cc1OCC)C(=O)Nc2cccc(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D20 compound treatment 639075.0 417000.0 0.86 673423.0 442000.0 0.96 1.2841 0.9986 1414493 CBMicro_000398 CC1CCCC(C)N1C(=O)c2c(C)onc2c3c(Cl)cccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D21 compound treatment 656094.0 434000.0 0.9 695200.0 463000.0 1.0 1.3422 0.9984 1923466 CBMicro_000399 CC(=O)c1cccc(NC(=O)c2cnn3c(cc(nc23)c4ccccc4)c5ccccc5)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D22 compound treatment 606343.0 384000.0 0.79 648567.0 417000.0 0.9 1.1982 0.9979 1447869 CBMicro_000400 COc1ccc(cc1)c2csc(Nc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D23 mock treatment 606713.0 384000.0 0.79 653092.0 421000.0 0.91 1.2057 0.9976 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 D24 mock treatment 227099.0 4700.0 0.01 187736.0 -44100.0 -0.1 -0.0606 -0.632 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E01 mock treatment 16136.0 -206000.0 -0.43 15644.0 -216000.0 -0.47 -0.6319 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E02 mock treatment 15079.0 -207000.0 -0.43 15550.0 -216000.0 -0.47 -0.6336 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E03 compound treatment 667497.0 445000.0 0.92 639135.0 407000.0 0.88 1.2731 0.9998 1475104 CBMicro_000401 CCc1ccc(OCC(=O)Nc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E04 compound treatment 664954.0 443000.0 0.91 660684.0 429000.0 0.93 1.3023 1.0 1383035 CBMicro_000402 CCC(=O)Nc1ccc2oc(nc2c1)c3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E05 compound treatment 710539.0 488000.0 1.01 655590.0 424000.0 0.92 1.3611 0.9989 1923467 CBMicro_000403 CC(C)OP(=O)(C)CN1CCCC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E06 compound treatment 664139.0 442000.0 0.91 652426.0 421000.0 0.91 1.2885 1.0 1697140 CBMicro_000404 COc1ccc(C(=O)Nc2cc(C)cc(C)c2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E07 compound treatment 810743.0 588000.0 1.21 754444.0 523000.0 1.13 1.6586 0.9994 1923468 CBMicro_000405 COc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1OC(=O)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E08 compound treatment 696287.0 474000.0 0.98 678126.0 446000.0 0.97 1.3748 1.0 1147208 CBMicro_000406 CC1=C(C(NC(=O)N1)c2ccc(O)cc2)C(=O)OCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E09 compound treatment 722292.0 500000.0 1.03 673709.0 442000.0 0.96 1.406 0.9993 1923469 CBMicro_000407 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E10 compound treatment 714674.0 492000.0 1.02 696528.0 465000.0 1.01 1.4298 1.0 1237496 CBMicro_000408 CCOc1cc(cc(OCC)c1OCC)C(=O)N(C)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E11 compound treatment 719851.0 497000.0 1.03 683200.0 451000.0 0.98 1.4169 0.9997 1923470 CBMicro_000409 COc1ccc(OC)c(/C=C/C(=O)Oc2cc(C)cc(C)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E12 compound treatment 732844.0 510000.0 1.05 698327.0 466000.0 1.01 1.459 0.9998 1923471 CBMicro_000410 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCc5ccccc5C4)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E13 compound treatment 734478.0 512000.0 1.06 721028.0 489000.0 1.06 1.4962 1.0 1111356 CBMicro_000411 c1ccc(cc1)c2nnnn2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E14 compound treatment 712811.0 490000.0 1.01 678717.0 447000.0 0.97 1.3998 0.9997 1178448 CBMicro_000412 CCc1ccccc1NC(=O)c2cc3cc(OC)ccc3oc2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E15 compound treatment 729014.0 507000.0 1.05 699319.0 467000.0 1.01 1.455 0.9999 1285878 CBMicro_000413 O=C(C1CC1)c2ccc3OCCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E16 compound treatment 703464.0 481000.0 0.99 692009.0 460000.0 1.0 1.4065 1.0 1923472 CBMicro_000414 CCN(CC)CCCNC(=O)c1ccc(Cl)cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E17 compound treatment 738452.0 516000.0 1.07 718843.0 487000.0 1.05 1.4986 1.0 1215640 CBMicro_000415 Cc1ccccc1OCC(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E18 compound treatment 665666.0 443000.0 0.92 1426580.0 1190000.0 2.59 2.4755 0.9025 1923473 CBMicro_000416 Cc1oc2ccccc2c1/C=N/n3cnc4sc5CCCCc5c4c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E19 compound treatment 673798.0 451000.0 0.93 692818.0 461000.0 1.0 1.3644 0.9994 1281894 CBMicro_000417 C=CCNC(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E20 compound treatment 664927.0 443000.0 0.91 697712.0 466000.0 1.01 1.359 0.9988 1923474 CBMicro_000418 CCOC(=O)c1cnn2c(cc(nc12)c3ccco3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E21 compound treatment 669581.0 447000.0 0.92 672099.0 440000.0 0.95 1.3266 0.9999 1923475 CBMicro_000419 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C\c3ccc4OCOc4c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E22 compound treatment 613026.0 391000.0 0.81 693480.0 462000.0 1.0 1.2767 0.9943 1260212 CBMicro_000420 COC(=O)c1cc(NC(=O)c2cc(OC)cc(OC)c2)cc(c1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E23 mock treatment 616204.0 394000.0 0.81 648563.0 417000.0 0.9 1.2126 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 E24 mock treatment 269289.0 46900.0 0.1 249089.0 17300.0 0.04 0.0949 0.9143 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F01 mock treatment 15466.0 -207000.0 -0.43 15948.0 -216000.0 -0.47 -0.6325 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F02 mock treatment 14566.0 -208000.0 -0.43 15424.0 -216000.0 -0.47 -0.6346 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F03 compound treatment 747975.0 526000.0 1.08 663938.0 432000.0 0.94 1.4285 0.9973 1923476 CBMicro_000421 FC(F)(F)c1ccc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F04 compound treatment 648240.0 426000.0 0.88 647080.0 415000.0 0.9 1.2571 0.9999 1923477 CBMicro_000422 [O-][N+](=O)c1cc(Br)ccc1N2C(=O)C3C(C4C=CC3C5CC54)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F05 compound treatment 656558.0 434000.0 0.9 684149.0 452000.0 0.98 1.326 0.999 1923478 CBMicro_000423 [O-][N+](=O)c1ccc2[nH]c(nc2c1)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F06 compound treatment 718998.0 497000.0 1.03 677792.0 446000.0 0.97 1.4074 0.9995 1466897 CBMicro_000424 O=C(Nc1ccccc1)C2CCC(=O)N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F07 compound treatment 717821.0 495000.0 1.02 736777.0 505000.0 1.09 1.496 0.9995 1923479 CBMicro_000425 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(cc3Cl)[N+](=O)[O-])/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F08 compound treatment 723439.0 501000.0 1.03 699375.0 468000.0 1.01 1.4469 0.9999 1560169 CBMicro_000426 COc1cc(cc(OC)c1OC(=O)c2ccc(C)cc2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F09 compound treatment 707170.0 485000.0 1.0 709917.0 478000.0 1.03 1.4393 0.9999 1923480 CBMicro_000427 Cc1ccccc1OCCSc2nc3ccc(Br)cc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F10 compound treatment 716617.0 494000.0 1.02 694524.0 463000.0 1.0 1.4295 1.0 1582464 CBMicro_000428 COc1ccc(cc1)C(=O)Oc2cccc(c2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F11 compound treatment 739652.0 517000.0 1.07 724547.0 493000.0 1.07 1.5091 1.0 1447625 CBMicro_000429 S=C(Nc1ccc2nc(c3ccccc3)c(nc2c1)c4ccccc4)N5CCN(CC5)c6ccccn6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F12 compound treatment 723694.0 501000.0 1.03 719110.0 487000.0 1.05 1.4775 1.0 1923481 CBMicro_000430 Cc1occc1C(=O)NNS(=O)(=O)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F13 compound treatment 719948.0 498000.0 1.03 726303.0 494000.0 1.07 1.483 0.9998 1708367 CBMicro_000431 COc1cccc(OCC(=O)NCc2ccncc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F14 compound treatment 717538.0 495000.0 1.02 693989.0 462000.0 1.0 1.4301 0.9999 1609970 CBMicro_000432 COc1ccc(Cl)cc1C(=O)Nc2cc(C)on2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F15 compound treatment 712390.0 490000.0 1.01 728347.0 497000.0 1.07 1.4751 0.9995 1640523 CBMicro_000433 O=C(N1CCC(C1)c2ccccc2)c3cc4ccccc4o3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F16 compound treatment 682625.0 460000.0 0.95 684926.0 453000.0 0.98 1.3652 0.9999 1923482 CBMicro_000434 COc1ccc(cc1OC)/C(=N/OC(=O)c2ccccc2I)/N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F17 compound treatment 706275.0 484000.0 1.0 750144.0 518000.0 1.12 1.4996 0.9983 1556185 CBMicro_000435 Clc1cccc(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F18 compound treatment 660833.0 438000.0 0.91 706218.0 474000.0 1.03 1.366 0.998 1923483 CBMicro_000436 O=C1NC(=S)NC(=O)C1=Cc2ccc(OCc3cccc4ccccc34)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F19 compound treatment 666014.0 444000.0 0.92 741670.0 510000.0 1.1 1.4278 0.9957 1923484 CBMicro_000437 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N(Cc2ccccc2)c3ccccn3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F20 compound treatment 642163.0 420000.0 0.87 697006.0 465000.0 1.01 1.3247 0.9972 1923485 CBMicro_000438 CN(Cc1ccccc1)C(=O)c2cc(Cl)ccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F21 compound treatment 650565.0 428000.0 0.88 721201.0 489000.0 1.06 1.3739 0.996 1923486 CBMicro_000439 Clc1ccc(C(=O)Nc2cc(NC(=O)c3cccs3)ccc2Cl)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F22 compound treatment 594170.0 372000.0 0.77 669034.0 437000.0 0.95 1.2118 0.9946 1923487 CBMicro_000440 CCN(CC)c1ccc(cc1)C(=O)Nc2ccccc2C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F23 mock treatment 600271.0 378000.0 0.78 667290.0 435000.0 0.94 1.218 0.9956 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 F24 mock treatment 247571.0 25200.0 0.05 216868.0 -15000.0 -0.03 0.0138 0.2261 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G01 mock treatment 15560.0 -207000.0 -0.43 14995.0 -217000.0 -0.47 -0.6338 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G02 mock treatment 15068.0 -207000.0 -0.43 15047.0 -217000.0 -0.47 -0.6344 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G03 compound treatment 701709.0 479000.0 0.99 649620.0 418000.0 0.9 1.339 0.999 1611708 CBMicro_000441 COc1ccc(cc1Br)C(=O)Nc2ccncc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G04 compound treatment 679745.0 457000.0 0.94 654527.0 423000.0 0.91 1.3145 0.9999 1114616 CBMicro_000442 Cc1ccc2nc(sc2c1)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G05 compound treatment 726199.0 504000.0 1.04 693092.0 461000.0 1.0 1.4413 0.9998 1923488 CBMicro_000443 CCOP(=O)(CN1CCCC1=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G06 compound treatment 689049.0 467000.0 0.96 636429.0 405000.0 0.88 1.3004 0.9989 1923489 CBMicro_000444 Cc1ccc(C(=O)CSc2nc(O)cc(O)n2)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G07 compound treatment 722632.0 500000.0 1.03 671856.0 440000.0 0.95 1.4036 0.9992 1923490 CBMicro_000445 Clc1ccc(C(=O)Nc2ccc(NC(=O)/C=C/c3ccco3)cc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G08 compound treatment 719389.0 497000.0 1.03 670619.0 439000.0 0.95 1.397 0.9993 1923491 CBMicro_000446 Cc1cccc(NCN2C(=O)S/C(=C/c3ccccc3Cl)/C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G09 compound treatment 759884.0 537000.0 1.11 699877.0 468000.0 1.01 1.5009 0.999 1923492 CBMicro_000447 N/C(=N/OCC(=O)Nc1ccc(F)cc1)/c2nonc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G10 compound treatment 748863.0 526000.0 1.09 680925.0 449000.0 0.97 1.4558 0.9984 1923493 CBMicro_000448 O=C(Oc1ccc(cc1)C(=S)N2CCOCC2)/C=C/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G11 compound treatment 752467.0 530000.0 1.09 697087.0 465000.0 1.01 1.4858 0.9991 1923494 CBMicro_000449 Nc1c(Cl)cc(cc1Cl)N2C(=O)C=CC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G12 compound treatment 718875.0 496000.0 1.02 671580.0 440000.0 0.95 1.3977 0.9993 1923495 CBMicro_000450 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N3CCc4ccccc4C3)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G13 compound treatment 774527.0 552000.0 1.14 726861.0 495000.0 1.07 1.5636 0.9995 1923496 CBMicro_000451 CCN(CC)c1ccc(NC(=O)/C=C/c2cc(OC)ccc2OC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G14 compound treatment 726598.0 504000.0 1.04 696553.0 465000.0 1.01 1.4472 0.9999 1315275 CBMicro_000452 COc1ccc(C(=O)N(Cc2ccccc2)c3ccccn3)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G15 compound treatment 744944.0 523000.0 1.08 718238.0 486000.0 1.05 1.5072 0.9999 1923497 CBMicro_000453 O/N=C\C(=O)NCCCNCc1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G16 compound treatment 705980.0 484000.0 1.0 703988.0 472000.0 1.02 1.4285 0.9999 1299669 CBMicro_000454 COc1ccc2oc(=O)c(cc2c1)C(=O)Nc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G17 compound treatment 762592.0 540000.0 1.12 725599.0 494000.0 1.07 1.5442 0.9998 1719090 CBMicro_000455 CCOc1ccc2N(C(=O)CN3C(=O)CCC3=O)C(C)(C)C=C(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G18 compound treatment 676083.0 454000.0 0.94 690498.0 459000.0 0.99 1.3642 0.9996 1923498 CBMicro_000456 Clc1ccc(OCC(=O)NCCCn2ccnc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G19 compound treatment 703936.0 482000.0 0.99 701459.0 470000.0 1.02 1.4216 0.9999 1690849 CBMicro_000457 COc1ccc(C(=O)Nc2ccc(Br)cc2C)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G20 compound treatment 690044.0 468000.0 0.97 678913.0 447000.0 0.97 1.3669 1.0 1923499 CBMicro_000458 Cc1c(Br)c(nn1CC(=O)N2CCc3ccccc3C2)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G21 compound treatment 669140.0 447000.0 0.92 682171.0 450000.0 0.97 1.3413 0.9996 1204253 CBMicro_000459 COc1cc(OC)cc(c1)C(=O)Nc2cccc(Cl)c2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G22 compound treatment 625344.0 403000.0 0.83 659519.0 428000.0 0.93 1.2427 0.9986 1632218 CBMicro_000460 COc1cc(OC)cc(c1)C(=O)Nc2cc(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G23 mock treatment 622094.0 400000.0 0.83 653729.0 422000.0 0.91 1.2291 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 G24 mock treatment 234890.0 12500.0 0.03 225926.0 -5910.0 -0.01 0.0092 0.3195 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H01 mock treatment 14503.0 -208000.0 -0.43 15121.0 -217000.0 -0.47 -0.6351 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H02 mock treatment 13958.0 -208000.0 -0.43 14974.0 -217000.0 -0.47 -0.6361 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H03 compound treatment 644539.0 422000.0 0.87 630635.0 399000.0 0.86 1.2265 1.0 1923500 CBMicro_000461 COc1ccc(OC)c(NC(=O)C(=O)NCc2ccncc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H04 compound treatment 634817.0 412000.0 0.85 629332.0 397000.0 0.86 1.2104 1.0 1923501 CBMicro_000462 CCN1C(=O)/C(=C\c2ccc(Cl)c(c2)[N+](=O)[O-])/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H05 compound treatment 666314.0 444000.0 0.92 701991.0 470000.0 1.02 1.3675 0.9986 1923502 CBMicro_000463 CCOC(=O)Cn1nc(c(Cl)c1C)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H06 compound treatment 675293.0 453000.0 0.93 669902.0 438000.0 0.95 1.3315 1.0 1923503 CBMicro_000464 Clc1c(sc2ccccc12)C(=O)Oc3ccc(C=O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H07 compound treatment 776515.0 554000.0 1.14 725882.0 494000.0 1.07 1.565 0.9994 1923504 CBMicro_000465 CCOc1cc(/C=C/2\SC(=S)N(C2=O)c3ccc(F)cc3)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H08 compound treatment 687311.0 465000.0 0.96 676804.0 445000.0 0.96 1.3596 1.0 1923505 CBMicro_000466 COc1ccccc1NC(=O)c2ccc(C)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H09 compound treatment 708848.0 486000.0 1.0 691855.0 460000.0 1.0 1.4141 1.0 1923506 CBMicro_000467 COc1ccc(OC)c(c1)C2=C/C(=C\c3c(OC)ccc4ccccc34)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H10 compound treatment 700649.0 478000.0 0.99 661395.0 430000.0 0.93 1.3555 0.9996 1227046 CBMicro_000468 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc(cc2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H11 compound treatment 700061.0 478000.0 0.99 675738.0 444000.0 0.96 1.3766 0.9999 1430858 CBMicro_000469 CC1(CC2CC3(C)C1)CC(CNC(=O)Nc4ccccc4)(C2)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H12 compound treatment 718463.0 496000.0 1.02 667691.0 436000.0 0.94 1.3912 0.9992 1923507 CBMicro_000470 NC1=NC(=O)CC(S1)C(=O)Nc2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H13 compound treatment 680685.0 458000.0 0.95 678426.0 447000.0 0.97 1.3524 0.9999 1291323 CBMicro_000471 COc1ccc(NC(=O)COc2ccccc2OC)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H14 compound treatment 732155.0 510000.0 1.05 706781.0 475000.0 1.03 1.471 0.9999 1352434 CBMicro_000472 Cn1c(NC(=O)c2ccc3OCOc3c2)cc(=O)n(C)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H15 compound treatment 717298.0 495000.0 1.02 711508.0 480000.0 1.04 1.4565 1.0 1872637 CBMicro_000473 Cc1cccc(c1)C2OC3(C4C2C(=O)N(C4=O)c5ccccc5Br)C(=O)c6ccccc6C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H16 compound treatment 648929.0 427000.0 0.88 699061.0 467000.0 1.01 1.3377 0.9976 1923508 CBMicro_000474 Cc1occc1C(=O)O/N=C(\N)/c2cccnc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H17 compound treatment 892136.0 670000.0 1.38 709796.0 478000.0 1.03 1.7091 0.9898 1602273 CBMicro_000475 COc1ccc(cc1)C(=O)Oc2cc(ccc2OC)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H18 compound treatment 762086.0 540000.0 1.11 787181.0 555000.0 1.2 1.6377 0.9993 1923509 CBMicro_000476 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1OC(=O)c3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H19 compound treatment 655492.0 433000.0 0.89 693027.0 461000.0 1.0 1.338 0.9985 1619681 CBMicro_000477 Cc1cccc(NC(=O)CC(c2ccccc2)c3ccccc3)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H20 compound treatment 640458.0 418000.0 0.86 648123.0 416000.0 0.9 1.2473 0.9998 1923510 CBMicro_000478 Clc1ccc(Cl)c(c1)C(=O)N2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H21 compound treatment 676685.0 454000.0 0.94 704223.0 472000.0 1.02 1.3861 0.9991 1923511 CBMicro_000479 FC(F)(F)c1cc(nc2c(cnn12)C(=O)NCCCn3ccnc3)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H22 compound treatment 589642.0 367000.0 0.76 633089.0 401000.0 0.87 1.1502 0.9977 1923512 CBMicro_000480 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2nc3ccccc3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H23 mock treatment 611654.0 389000.0 0.8 656817.0 425000.0 0.92 1.2186 0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 H24 mock treatment 238439.0 16000.0 0.03 259896.0 28100.0 0.06 0.0664 0.9593 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I01 mock treatment 15267.0 -207000.0 -0.43 14995.0 -217000.0 -0.47 -0.6342 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I02 mock treatment 14597.0 -208000.0 -0.43 13016.0 -219000.0 -0.47 -0.6382 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I03 compound treatment 867993.0 646000.0 1.33 792977.0 561000.0 1.21 1.8012 0.9989 1571724 CBMicro_000481 CCCC(=O)Nc1ccc(NC(=O)c2cc(Br)ccc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I04 compound treatment 713618.0 491000.0 1.01 669493.0 438000.0 0.95 1.3868 0.9994 2493 CBMicro_000482 CCC(=O)Nc1ccc(Cl)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I05 compound treatment 733696.0 511000.0 1.06 682350.0 451000.0 0.98 1.4358 0.9992 1923513 CBMicro_000483 CCOC(=O)N(CCCC(=O)OC)CP(=O)(OCC)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I06 compound treatment 685998.0 464000.0 0.96 658062.0 426000.0 0.92 1.329 0.9998 1923514 CBMicro_000484 Cc1cc(O)nc(SCC(=O)c2ccc(Br)cc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I07 compound treatment 752636.0 530000.0 1.09 686168.0 454000.0 0.98 1.4693 0.9986 1923515 CBMicro_000485 COc1ccc(cc1OC)C(=O)/C=C/Nc2ccccc2Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I08 compound treatment 719931.0 498000.0 1.03 662126.0 430000.0 0.93 1.3848 0.9988 1366821 CBMicro_000486 C(c1ccccc1)n2c(nc3ccccc23)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I09 compound treatment 723320.0 501000.0 1.03 675048.0 443000.0 0.96 1.4095 0.9993 1610117 CBMicro_000487 OC(c1ccccc1)P(=O)(O)CCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I10 compound treatment 724395.0 502000.0 1.04 651009.0 419000.0 0.91 1.3743 0.9978 1563301 CBMicro_000488 COc1cc(cc(OC)c1OC)C(=O)N2CCc3ccccc3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I11 compound treatment 806596.0 584000.0 1.21 677945.0 446000.0 0.97 1.5355 0.9939 1923516 CBMicro_000489 O/N=C/c1cn(nc1c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I12 compound treatment 736198.0 514000.0 1.06 675014.0 443000.0 0.96 1.4283 0.9987 1154658 CBMicro_000490 COc1ccc(OC)c(NC(=O)C2c3ccccc3Oc4ccccc24)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I13 compound treatment 718078.0 496000.0 1.02 682090.0 450000.0 0.97 1.4126 0.9997 1923517 CBMicro_000491 Clc1ccccc1/C=C/C(=O)Nc2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I14 compound treatment 725598.0 503000.0 1.04 703859.0 472000.0 1.02 1.4569 1.0 1923518 CBMicro_000492 COc1ccc(NC(=O)C(=O)NCc2ccco2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I15 compound treatment 775709.0 553000.0 1.14 710580.0 479000.0 1.04 1.5404 0.9988 1923519 CBMicro_000493 Brc1cccc(c1)C(=O)Nc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I16 compound treatment 714304.0 492000.0 1.02 682881.0 451000.0 0.98 1.4083 0.9998 1923520 CBMicro_000494 CN(C)C(=O)c1sc2ccccc2c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I17 compound treatment 711245.0 489000.0 1.01 721924.0 490000.0 1.06 1.4636 0.9997 1675691 CBMicro_000495 COc1cc(OC)cc(c1)C(=O)Nc2c(C)cccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I18 compound treatment 658435.0 436000.0 0.9 678097.0 446000.0 0.97 1.3195 0.9994 1923521 CBMicro_000496 CN(C)/C=N/n1cnc2scc(c3ccc(Cl)cc3)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I19 compound treatment 688302.0 466000.0 0.96 692848.0 461000.0 1.0 1.3856 0.9998 1923522 CBMicro_000497 Cc1ccc(C)c(NCN2C(=O)S/C(=C/c3cccc(Br)c3)/C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I20 compound treatment 659912.0 438000.0 0.9 728133.0 496000.0 1.07 1.3982 0.9963 1339405 CBMicro_000498 Cc1ccnc(NS(=O)(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I21 compound treatment 697048.0 475000.0 0.98 683635.0 452000.0 0.98 1.3843 1.0 1181779 CBMicro_000499 COc1cc(OC)cc(c1)C(=O)Nc2cccc(c2)c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I22 compound treatment 605746.0 383000.0 0.79 651289.0 419000.0 0.91 1.2015 0.9977 1148435 CBMicro_000500 COc1cccc2cc(C(=O)Nc3ccc(I)cc3)c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I23 mock treatment 616314.0 394000.0 0.81 642009.0 410000.0 0.89 1.2027 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 I24 mock treatment 258053.0 35700.0 0.07 237884.0 6050.0 0.01 0.0613 0.8201 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J01 mock treatment 14450.0 -208000.0 -0.43 15623.0 -216000.0 -0.47 -0.6344 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J02 mock treatment 14094.0 -208000.0 -0.43 15320.0 -217000.0 -0.47 -0.6354 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J03 compound treatment 673601.0 451000.0 0.93 648833.0 417000.0 0.9 1.2968 0.9999 1923523 CBMicro_000501 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3cc(F)c(F)cc3Cl)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J04 compound treatment 665527.0 443000.0 0.91 645621.0 414000.0 0.9 1.2801 0.9999 1923524 CBMicro_000502 COc1ccc(N2C(=O)C3C(C4C=CC3C5CC54)C2=O)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J05 compound treatment 686427.0 464000.0 0.96 677374.0 446000.0 0.96 1.3592 1.0 1923525 CBMicro_000503 Cc1c(Cl)c(nn1CC(=O)NCc2ccc(Cl)cc2)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J06 compound treatment 661133.0 439000.0 0.91 649803.0 418000.0 0.9 1.2801 1.0 1616677 CBMicro_000504 NC1=C(C#N)C(c2ccc(Cl)cc2Cl)c3ccc4cccnc4c3O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J07 compound treatment 690622.0 468000.0 0.97 584012.0 352000.0 0.76 1.2225 0.9931 1413227 CBMicro_000505 Nc1nc2CCc3ccccc3-c2s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J08 compound treatment 687615.0 465000.0 0.96 669707.0 438000.0 0.95 1.3492 1.0 1229118 CBMicro_000506 COc1cccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C#N)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J09 compound treatment 704794.0 482000.0 1.0 704064.0 472000.0 1.02 1.4269 0.9999 1923526 CBMicro_000507 Fc1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J10 compound treatment 697016.0 475000.0 0.98 669457.0 438000.0 0.95 1.3626 0.9999 1541106 CBMicro_000508 COc1cc(cc(OC)c1OC(=O)c2ccc(Br)cc2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J11 compound treatment 721541.0 499000.0 1.03 731328.0 499000.0 1.08 1.493 0.9997 1656248 CBMicro_000509 CCOC(=O)C1CCN(CC1)C(=O)C2c3ccccc3Oc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J12 compound treatment 683210.0 461000.0 0.95 688415.0 457000.0 0.99 1.3714 0.9998 1634622 CBMicro_000510 O=C(CN1C(=O)c2ccccc2C1=O)NC(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J13 compound treatment 708390.0 486000.0 1.0 713787.0 482000.0 1.04 1.447 0.9998 1286741 CBMicro_000511 COc1cccc(OCC(=O)Nc2ccc3OCCOc3c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J14 compound treatment 682008.0 460000.0 0.95 693007.0 461000.0 1.0 1.3767 0.9997 1207216 CBMicro_000512 COC(=O)c1c(NC(=O)Nc2ccc(Cl)c(Cl)c2)sc3CCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J15 compound treatment 692978.0 471000.0 0.97 696634.0 465000.0 1.01 1.3983 0.9998 1781318 CBMicro_000513 Cc1csc(NC(=O)c2ccc(Cl)cc2[N+](=O)[O-])n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J16 compound treatment 676917.0 455000.0 0.94 703049.0 471000.0 1.02 1.3846 0.9991 1414942 CBMicro_000514 Clc1ccc(NC(=O)NCc2ccccn2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J17 compound treatment 668098.0 446000.0 0.92 673747.0 442000.0 0.96 1.3269 0.9998 1472330 CBMicro_000515 Cc1onc(c1C(=O)Nc2ccccc2Oc3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J18 compound treatment 699032.0 477000.0 0.98 729090.0 497000.0 1.08 1.4568 0.999 1923527 CBMicro_000516 COc1cc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)ccc1OC(=O)c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J19 compound treatment 654195.0 432000.0 0.89 708073.0 476000.0 1.03 1.3592 0.9974 1629141 CBMicro_000517 Clc1cccc(Cl)c1C(=O)NCC2CCCO2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J20 compound treatment 613376.0 391000.0 0.81 697742.0 466000.0 1.01 1.2838 0.9939 1923528 CBMicro_000518 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3c(Cl)cccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J21 compound treatment 626887.0 404000.0 0.83 708327.0 476000.0 1.03 1.3197 0.9945 1923529 CBMicro_000519 CCOC(=O)c1c(C)nc2CC(C)(C)C/C(=N\O)/c2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J22 compound treatment 585344.0 363000.0 0.75 667211.0 435000.0 0.94 1.1961 0.9935 1781606 CBMicro_000520 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCN(C)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J23 mock treatment 587024.0 365000.0 0.75 655746.0 424000.0 0.92 1.181 0.9952 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 J24 mock treatment 200961.0 -21400.0 -0.04 448878.0 217000.0 0.47 0.3009 0.6377 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K01 mock treatment 14555.0 -208000.0 -0.43 14765.0 -217000.0 -0.47 -0.6356 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K02 mock treatment 14702.0 -208000.0 -0.43 14409.0 -217000.0 -0.47 -0.6359 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K03 compound treatment 690691.0 468000.0 0.97 641122.0 409000.0 0.89 1.31 0.999 1190794 CBMicro_000521 CCOc1cccc(c1)C(=O)Nc2cccc(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K04 compound treatment 680358.0 458000.0 0.95 623924.0 392000.0 0.85 1.2686 0.9985 1923530 CBMicro_000522 COc1ccc(CO/N=C(/N)\c2nonc2N)cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K05 compound treatment 1237791.0 1020000.0 2.1 1106145.0 874000.0 1.89 2.8202 0.9987 1923531 CBMicro_000523 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1OC(=O)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K06 compound treatment 695284.0 473000.0 0.98 642981.0 411000.0 0.89 1.3195 0.9989 1923532 CBMicro_000524 COc1ccc(cc1)C(=O)CSc2nc(N)cc(O)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K07 compound treatment 725517.0 503000.0 1.04 656920.0 425000.0 0.92 1.385 0.9982 1923533 CBMicro_000525 O=C(Nc1ccc(NC(=O)c2ccco2)cc1)/C=C/c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K08 compound treatment 906210.0 684000.0 1.41 867679.0 636000.0 1.38 1.9713 0.9999 1923534 CBMicro_000526 Cn1c(/C=C/c2ccco2)nc3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K09 compound treatment 749335.0 527000.0 1.09 686475.0 455000.0 0.98 1.465 0.9987 1256853 CBMicro_000527 Cc1ccccc1OCC(=O)Nc2cccc(c2)c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K10 compound treatment 726565.0 504000.0 1.04 665009.0 433000.0 0.94 1.3989 0.9986 1923535 CBMicro_000528 COCCNC(=O)Nc1ccc2nccnc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K11 compound treatment 713206.0 491000.0 1.01 671077.0 439000.0 0.95 1.3887 0.9995 1923536 CBMicro_000529 CC(=C1C2C=CC1C3C2C(=O)N(C3=O)c4ccccc4[N+](=O)[O-])C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K12 compound treatment 699462.0 477000.0 0.98 659006.0 427000.0 0.92 1.3501 0.9995 1923537 CBMicro_000530 C=CCNC(=O)Nc1ccc2nccnc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K13 compound treatment 727623.0 505000.0 1.04 683781.0 452000.0 0.98 1.4292 0.9995 1496333 CBMicro_000531 COc1ccc(cc1)C(=O)N2CCC(C2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K14 compound treatment 690938.0 469000.0 0.97 654883.0 423000.0 0.92 1.3314 0.9996 1923538 CBMicro_000532 FC(F)(F)c1cc(nc2c(cnn12)C(=O)N3CCCc4ccccc34)c5cccs5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K15 compound treatment 720834.0 498000.0 1.03 681535.0 450000.0 0.97 1.4158 0.9996 1504163 CBMicro_000533 C=CCNS(=O)(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K16 compound treatment 672235.0 450000.0 0.93 680440.0 449000.0 0.97 1.3432 0.9998 1664826 CBMicro_000534 O=C(N1CCOCC1)c2cnn3c(cc(nc23)c4ccccc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K17 compound treatment 704964.0 483000.0 1.0 702798.0 471000.0 1.02 1.4252 0.9999 1536601 CBMicro_000535 Cc1ccc(cc1C)S(=O)(=O)NCc2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K18 compound treatment 675080.0 453000.0 0.93 681434.0 450000.0 0.97 1.3489 0.9998 1923539 CBMicro_000536 Oc1cc(nn1c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K19 compound treatment 671217.0 449000.0 0.93 693341.0 462000.0 1.0 1.3615 0.9993 1923540 CBMicro_000537 COc1ccc(cc1OC)C(=O)Nc2ncc(s2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K20 compound treatment 634717.0 412000.0 0.85 668603.0 437000.0 0.95 1.2703 0.9986 1923541 CBMicro_000538 CCOC(=O)/C(=C\Nc1ccc(F)c(F)c1F)/[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K21 compound treatment 637918.0 416000.0 0.86 700243.0 468000.0 1.01 1.3234 0.9965 1571421 CBMicro_000539 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K22 compound treatment 611243.0 389000.0 0.8 653999.0 422000.0 0.91 1.2137 0.9979 1559668 CBMicro_000540 COc1ccc(C(=O)Nc2ccc(Br)c(C)c2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K23 mock treatment 604164.0 382000.0 0.79 663984.0 432000.0 0.94 1.2186 0.9964 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 K24 mock treatment 227455.0 5060.0 0.01 266231.0 34400.0 0.07 0.06 0.7984 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L01 mock treatment 14283.0 -208000.0 -0.43 14691.0 -217000.0 -0.47 -0.6361 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L02 mock treatment 14210.0 -208000.0 -0.43 12922.0 -219000.0 -0.47 -0.6389 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L03 compound treatment 666916.0 445000.0 0.92 634162.0 402000.0 0.87 1.2646 0.9997 1923542 CBMicro_000541 COc1ccc(NC(=O)C(=O)NCc2ccccn2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L04 compound treatment 657301.0 435000.0 0.9 631519.0 400000.0 0.87 1.2465 0.9998 1778802 CBMicro_000542 Cc1c(Cl)cccc1NC(=O)Cn2cnc(n2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L05 compound treatment 673070.0 451000.0 0.93 675615.0 444000.0 0.96 1.337 0.9999 1923543 CBMicro_000543 Cc1c(Cl)c(nn1CC(=O)Nc2ccccc2C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L06 compound treatment 657802.0 435000.0 0.9 653251.0 421000.0 0.91 1.2805 1.0 1624282 CBMicro_000544 COc1ccccc1N2CCN(CC2)C(=O)c3ccccc3Oc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L07 compound treatment 694284.0 472000.0 0.97 671305.0 439000.0 0.95 1.3614 0.9999 1923544 CBMicro_000545 COc1ccc(Cl)cc1NC(=O)Cn2nc(cc2C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L08 compound treatment 676054.0 454000.0 0.94 702895.0 471000.0 1.02 1.3831 0.9991 1133397 CBMicro_000546 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C#N)C3c4ccc(cc4)N(C)C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L09 compound treatment 683869.0 461000.0 0.95 757147.0 525000.0 1.14 1.4776 0.9961 1923545 CBMicro_000547 [O-][N+](=O)c1ccc(Cl)c(c1)N2CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L10 compound treatment 665298.0 443000.0 0.91 646252.0 414000.0 0.9 1.2807 1.0 1433000 CBMicro_000548 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2cccc(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L11 compound treatment 691354.0 469000.0 0.97 670284.0 438000.0 0.95 1.3556 1.0 1923546 CBMicro_000549 Fc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(F)c(Cl)c3)C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L12 compound treatment 644840.0 422000.0 0.87 636697.0 405000.0 0.88 1.2363 1.0 1483673 CBMicro_000550 CCC(C(=O)N1CCN(CC1)c2cccc(Cl)c2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L13 compound treatment 695595.0 473000.0 0.98 677864.0 446000.0 0.97 1.3733 1.0 1631729 CBMicro_000551 COc1ccc(OCC(=O)Nc2ccc3OCCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L14 compound treatment 665418.0 443000.0 0.91 694248.0 462000.0 1.0 1.3544 0.999 1923547 CBMicro_000552 COc1ccc(NC(=O)c2sc3cc(C)ccc3c2Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L15 compound treatment 686637.0 464000.0 0.96 708665.0 477000.0 1.03 1.4074 0.9993 1923548 CBMicro_000553 CN(C)CCNC(=O)/C(=N\O)/c1ccccn1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L16 compound treatment 648057.0 426000.0 0.88 675312.0 443000.0 0.96 1.3001 0.999 1923549 CBMicro_000554 CCCCOc1ccc(NC(=O)c2cccc(OC)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L17 compound treatment 676932.0 455000.0 0.94 704768.0 473000.0 1.02 1.3873 0.9991 1398369 CBMicro_000555 Cc1ccc(o1)C(=O)Nc2ccccc2Oc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L18 compound treatment 643271.0 421000.0 0.87 673798.0 442000.0 0.96 1.2907 0.9988 1193813 CBMicro_000556 NC(=O)c1cc(NC(=O)c2ccc(Cl)c(Cl)c2)ccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L19 compound treatment 627364.0 405000.0 0.84 686314.0 454000.0 0.98 1.2867 0.9967 1923550 CBMicro_000557 Cc1onc(c1C(=O)NCCNc2c(Cl)cccc2[N+](=O)[O-])c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L20 compound treatment 607959.0 386000.0 0.8 698161.0 466000.0 1.01 1.2765 0.9931 1923551 CBMicro_000558 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc(cc2)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L21 compound treatment 632152.0 410000.0 0.85 712980.0 481000.0 1.04 1.3345 0.9947 1923552 CBMicro_000559 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C/c3ccco3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L22 compound treatment 591098.0 369000.0 0.76 674090.0 442000.0 0.96 1.215 0.9936 1781604 CBMicro_000560 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L23 mock treatment 571331.0 349000.0 0.72 664049.0 432000.0 0.94 1.1708 0.9917 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 L24 mock treatment 263750.0 41400.0 0.09 230376.0 -1460.0 0.0 0.0581 0.6805 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M01 mock treatment 14251.0 -208000.0 -0.43 14398.0 -217000.0 -0.47 -0.6366 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M02 mock treatment 14398.0 -208000.0 -0.43 12304.0 -220000.0 -0.48 -0.6396 -0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M03 compound treatment 700426.0 478000.0 0.99 624110.0 392000.0 0.85 1.2981 0.9972 1923553 CBMicro_000561 COc1ccc(cc1OC)C(=O)/C=C/Nc2ccccc2NS(=O)(=O)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M04 compound treatment 657770.0 435000.0 0.9 612811.0 381000.0 0.82 1.2186 0.9991 1923554 CBMicro_000562 Ic1ccc(/C=N/N2C(=O)C3C(C4CCC3C=C4)C2=O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M05 compound treatment 691765.0 469000.0 0.97 655047.0 423000.0 0.92 1.3328 0.9996 1574349 CBMicro_000563 COc1ccccc1NC(=O)C2CCC(=O)N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M06 compound treatment 677042.0 455000.0 0.94 619738.0 388000.0 0.84 1.2573 0.9985 1923555 CBMicro_000564 COc1ccc(cc1)C(=O)CSc2nc(C)cc(O)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M07 compound treatment 691185.0 469000.0 0.97 647219.0 415000.0 0.9 1.32 0.9993 1923556 CBMicro_000565 COc1ccc(cc1OC)C(=O)/C=C/Nc2ccc(Cl)cc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M08 compound treatment 683229.0 461000.0 0.95 636206.0 404000.0 0.88 1.2915 0.9991 1923557 CBMicro_000566 Cn1cc(c2nc3ccccc3[nH]2)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M09 compound treatment 711456.0 489000.0 1.01 654466.0 423000.0 0.91 1.3607 0.9988 1923558 CBMicro_000567 COc1ccccc1/C=C\2/SC(=O)N(CNc3cccc(c3)[N+](=O)[O-])C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M10 compound treatment 748405.0 526000.0 1.09 635783.0 404000.0 0.87 1.386 0.9942 1783008 CBMicro_000568 [O-][N+](=O)c1ccc(CC(=O)NCc2ccccn2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M11 compound treatment 717661.0 495000.0 1.02 668807.0 437000.0 0.95 1.3917 0.9992 1923559 CBMicro_000569 Cc1ccc(cc1[N+](=O)[O-])N2C(=O)C=CC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M12 compound treatment 951716.0 729000.0 1.51 952147.0 720000.0 1.56 2.167 0.9998 1923560 CBMicro_000570 Cc1cc(co1)c2cc(nc(N)c2C#N)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M13 compound treatment 704434.0 482000.0 1.0 678946.0 447000.0 0.97 1.3879 0.9999 1923561 CBMicro_000571 COC(=O)c1ccc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M14 compound treatment 665445.0 443000.0 0.91 641642.0 410000.0 0.89 1.2739 0.9999 1923562 CBMicro_000572 CCOC(=O)c1c(NC(=O)Cn2nc(cc2C)C(F)(F)F)sc3CC(C)CCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M15 compound treatment 680056.0 458000.0 0.94 652686.0 421000.0 0.91 1.3121 0.9998 1546150 CBMicro_000573 Cc1ccc2N(C(=O)CSc3nc4ccccc4o3)C(C)(C)c5ssc(=S)c5-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M16 compound treatment 668204.0 446000.0 0.92 665422.0 434000.0 0.94 1.3143 1.0 1135482 CBMicro_000574 CCC(=O)Nc1ccc2C(=O)N(C)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M17 compound treatment 713085.0 491000.0 1.01 680291.0 448000.0 0.97 1.4026 0.9998 1122859 CBMicro_000575 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cccc(OC)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M18 compound treatment 642462.0 420000.0 0.87 648044.0 416000.0 0.9 1.2502 0.9998 1923563 CBMicro_000576 CN(C1CCN(C)CC1)S(=O)(=O)c2ccccc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M19 compound treatment 653340.0 431000.0 0.89 680623.0 449000.0 0.97 1.3159 0.999 1255309 CBMicro_000577 Cc1ccc(cc1C)C(=O)N2CCN(CC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M20 compound treatment 601491.0 379000.0 0.78 665973.0 434000.0 0.94 1.2178 0.9959 1568434 CBMicro_000578 O=C1N(C(=O)c2ccccc12)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M21 compound treatment 622613.0 400000.0 0.83 727760.0 496000.0 1.07 1.3432 0.9916 1704966 CBMicro_000579 CCOc1ccc(c2ccccc12)S(=O)(=O)Nc3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M22 compound treatment 578017.0 356000.0 0.73 667679.0 436000.0 0.94 1.1861 0.9923 1250738 CBMicro_000580 CCOc1ccc(NC(=O)c2ccc(cc2)N3C(=O)c4cccnc4C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M23 mock treatment 600364.0 378000.0 0.78 648406.0 417000.0 0.9 1.1893 0.9974 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 M24 mock treatment 272514.0 50100.0 0.1 157378.0 -74500.0 -0.16 -0.0408 -0.213 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N01 mock treatment 14838.0 -208000.0 -0.43 15414.0 -216000.0 -0.47 -0.6342 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N02 mock treatment 14346.0 -208000.0 -0.43 14670.0 -217000.0 -0.47 -0.636 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N03 compound treatment 699178.0 477000.0 0.98 638184.0 406000.0 0.88 1.3179 0.9984 1923564 CBMicro_000581 Cc1c(Br)c(nn1CC(=O)Nc2cc(ccc2Cl)C(F)(F)F)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N04 compound treatment 691810.0 469000.0 0.97 624866.0 393000.0 0.85 1.2867 0.9979 1125113 CBMicro_000582 CCOC(=O)c1[nH]cnc1C(=O)N2CCCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N05 compound treatment 652456.0 430000.0 0.89 663195.0 431000.0 0.93 1.2879 0.9997 1923565 CBMicro_000583 COCCNC(=O)c1cnn2c(cc(nc12)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N06 compound treatment 650227.0 428000.0 0.88 642578.0 411000.0 0.89 1.2531 1.0 1158852 CBMicro_000584 Brc1cccc(NC(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N07 compound treatment 646174.0 424000.0 0.87 699816.0 468000.0 1.01 1.3348 0.9973 1923566 CBMicro_000585 CN1C(=O)C2(NN=C(S2)c3cccc4ccccc34)c5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N08 compound treatment 643374.0 421000.0 0.87 629879.0 398000.0 0.86 1.2237 1.0 1156046 CBMicro_000586 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2ccc(C)c(C)c2)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N09 compound treatment 657578.0 435000.0 0.9 642060.0 410000.0 0.89 1.2631 1.0 1585728 CBMicro_000587 Cc1cc(nc2cc(nn12)C(=O)N3CCCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N10 compound treatment 652090.0 430000.0 0.89 646728.0 415000.0 0.9 1.2622 1.0 1579170 CBMicro_000588 CN(Cc1ccccc1)C(=O)c2ccc3OCCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N11 compound treatment 648245.0 426000.0 0.88 674915.0 443000.0 0.96 1.2997 0.9991 1923567 CBMicro_000589 COCCNC(=O)c1cc2nc(cc(c3ccccc3)n2n1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N12 compound treatment 630598.0 408000.0 0.84 636487.0 405000.0 0.88 1.2151 0.9998 1923568 CBMicro_000590 CCCCOc1ccc(NC(=O)c2ccncc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N13 compound treatment 661377.0 439000.0 0.91 653136.0 421000.0 0.91 1.2856 1.0 1733716 CBMicro_000591 COc1ccccc1OCC(=O)N2CCN(C)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N14 compound treatment 662712.0 440000.0 0.91 672039.0 440000.0 0.95 1.3164 0.9997 1923569 CBMicro_000592 OCCN(C(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N15 compound treatment 638552.0 416000.0 0.86 653627.0 422000.0 0.91 1.253 0.9995 1669013 CBMicro_000593 Clc1ccc(CC(=O)Nc2ccc3OCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N16 compound treatment 624219.0 402000.0 0.83 688155.0 456000.0 0.99 1.2849 0.9962 1923570 CBMicro_000594 COc1cc(/C=C\2/SC(=S)N(CC(=O)N3CCOCC3)C2=O)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N17 compound treatment 652421.0 430000.0 0.89 683031.0 451000.0 0.98 1.3182 0.9989 1164465 CBMicro_000595 CN(C)c1cccc(c1)C(=O)NCC2CCCO2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N18 compound treatment 615202.0 393000.0 0.81 637454.0 406000.0 0.88 1.1942 0.9992 1507234 CBMicro_000596 COc1cc(NC(=O)c2ccccc2)c(Cl)cc1NC(=O)c3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N19 compound treatment 599749.0 377000.0 0.78 666801.0 435000.0 0.94 1.2165 0.9956 1923571 CBMicro_000597 CC1CN(CCN1C(=O)c2c(C)onc2c3ccccc3Cl)c4ccc(cc4Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N20 compound treatment 626859.0 404000.0 0.83 639135.0 407000.0 0.88 1.2137 0.9996 1923572 CBMicro_000598 CC(=O)Nc1ccc(cc1)C(=O)Nc2ncc(s2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N21 compound treatment 617335.0 395000.0 0.82 660919.0 429000.0 0.93 1.2332 0.9979 1923573 CBMicro_000599 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCc3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N22 compound treatment 588033.0 366000.0 0.75 647540.0 416000.0 0.9 1.1699 0.9962 1573383 CBMicro_000600 CC(=O)Nc1ccc(cc1)C(=O)NCc2ccccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N23 mock treatment 582366.0 360000.0 0.74 650898.0 419000.0 0.91 1.1668 0.9951 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 N24 mock treatment 394834.0 172000.0 0.36 186783.0 -45000.0 -0.1 0.1828 0.4952 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O01 mock treatment 15508.0 -207000.0 -0.43 14691.0 -217000.0 -0.47 -0.6343 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O02 mock treatment 14461.0 -208000.0 -0.43 14587.0 -217000.0 -0.47 -0.636 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O03 compound treatment 659754.0 437000.0 0.9 618872.0 387000.0 0.84 1.2307 0.9993 1707863 CBMicro_000601 OC(=O)c1ccccc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O04 compound treatment 662062.0 440000.0 0.91 584882.0 353000.0 0.76 1.1821 0.9963 1268034 CBMicro_000602 CCOc1ccc2nc(NC(=O)CCC(=O)O)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O05 compound treatment 649436.0 427000.0 0.88 617000.0 385000.0 0.83 1.2128 0.9996 1124779 CBMicro_000603 CN(CP(=O)(O)CCc1ccccc1)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O06 compound treatment 622524.0 400000.0 0.83 606126.0 374000.0 0.81 1.1569 1.0 1923574 CBMicro_000604 Oc1cccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O07 compound treatment 705944.0 484000.0 1.0 667691.0 436000.0 0.94 1.3729 0.9996 1923575 CBMicro_000605 COc1ccc(cc1OC)C(=O)/C=C/NCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O08 compound treatment 646529.0 424000.0 0.88 613595.0 382000.0 0.83 1.2034 0.9996 1738368 CBMicro_000606 Cc1oc(cc1C(=O)c2ccccc2)c3nc4ccccc4n3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O09 compound treatment 656143.0 434000.0 0.9 613365.0 382000.0 0.83 1.217 0.9992 1295910 CBMicro_000607 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(NC(=O)c4ccc(Cl)cc4Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O10 compound treatment 634270.0 412000.0 0.85 614865.0 383000.0 0.83 1.1874 0.9999 1542934 CBMicro_000608 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(NC(=O)C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O11 compound treatment 639881.0 417000.0 0.86 604978.0 373000.0 0.81 1.1805 0.9995 1873848 CBMicro_000609 CCOC(=O)/C=C(/C)\Nc1c(C)n(C)n(c2ccccc2)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O12 compound treatment 610262.0 388000.0 0.8 593092.0 361000.0 0.78 1.1191 0.9999 1923576 CBMicro_000610 COc1ccc(CCNC(=O)C(=O)NCc2ccc(C)cc2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O13 compound treatment 645431.0 423000.0 0.87 596527.0 365000.0 0.79 1.1756 0.9987 1456180 CBMicro_000611 CC(Oc1ccccc1)C(=O)Nc2cccc(NC(=O)C(C)Oc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O14 compound treatment 624377.0 402000.0 0.83 619873.0 388000.0 0.84 1.1806 1.0 1923577 CBMicro_000612 CC(C)OC(=O)c1cnn2c(cc(nc12)c3ccc(F)cc3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O15 compound treatment 637593.0 415000.0 0.86 628910.0 397000.0 0.86 1.2138 1.0 1923578 CBMicro_000613 COc1ccccc1/C=C\2/SC(=S)N(CNc3ccc(C)c(Cl)c3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O16 compound treatment 621098.0 399000.0 0.82 613419.0 382000.0 0.83 1.166 1.0 1524172 CBMicro_000614 Clc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)cc2Cl)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O17 compound treatment 635967.0 414000.0 0.85 654084.0 422000.0 0.91 1.2499 0.9994 1226247 CBMicro_000615 Cc1ccc(cc1C)S(=O)(=O)Nc2ccccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O18 compound treatment 596177.0 374000.0 0.77 624607.0 393000.0 0.85 1.1467 0.9988 1598096 CBMicro_000616 CCOc1cc(cc(OCC)c1OCC)C(=O)NCc2ccccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O19 compound treatment 613361.0 391000.0 0.81 624058.0 392000.0 0.85 1.171 0.9997 1658690 CBMicro_000617 Clc1ccccc1NC(=O)c2ccc3nccnc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O20 compound treatment 578328.0 356000.0 0.73 606066.0 374000.0 0.81 1.0923 0.9988 1779881 CBMicro_000618 [O-][N+](=O)c1cccc(c1)N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Br)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O21 compound treatment 590939.0 369000.0 0.76 633044.0 401000.0 0.87 1.152 0.9978 1501777 CBMicro_000619 COc1cc(OC)cc(c1)C(=O)Nc2ccc(C)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O22 compound treatment 567286.0 345000.0 0.71 587214.0 355000.0 0.77 1.0473 0.9993 1537068 CBMicro_000620 COc1ccc(CNC(=O)c2cc(OC)cc(OC)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O23 mock treatment 573326.0 351000.0 0.72 625117.0 393000.0 0.85 1.1141 0.9968 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 O24 mock treatment 207663.0 -14700.0 -0.03 386509.0 155000.0 0.33 0.2152 0.6402 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P01 mock treatment 15445.0 -207000.0 -0.43 15152.0 -217000.0 -0.47 -0.6337 -0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P02 mock treatment 15162.0 -207000.0 -0.43 15560.0 -216000.0 -0.47 -0.6335 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P03 compound treatment 592386.0 370000.0 0.76 557359.0 326000.0 0.7 1.0383 0.9992 1134342 CBMicro_000621 Cc1c(NC(=O)c2cc3nc(cc(C)n3n2)c4ccccc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P04 compound treatment 642586.0 420000.0 0.87 620642.0 389000.0 0.84 1.2084 0.9999 1923579 CBMicro_000622 OC(=O)CN1C(=O)/C(=C\c2ccc(OC(=O)c3ccc(Cl)cc3Cl)cc2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P05 compound treatment 592200.0 370000.0 0.76 557401.0 326000.0 0.7 1.0381 0.9992 1923580 CBMicro_000623 [O-][N+](=O)c1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCCc5ccccc45)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P06 compound treatment 604796.0 382000.0 0.79 566411.0 335000.0 0.72 1.0702 0.9991 1358338 CBMicro_000624 Cc1cccc(NC(=O)Nc2ccc(cc2)c3nc4ccccc4s3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P07 compound treatment 614740.0 392000.0 0.81 612466.0 381000.0 0.82 1.1552 1.0 1923581 CBMicro_000625 Cc1cccc(c1)C(=O)Oc2ccc(/C=C\3/SC(=S)NC3=O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P08 compound treatment 600294.0 378000.0 0.78 604187.0 372000.0 0.81 1.1215 0.9999 1923582 CBMicro_000626 CCOC(=O)c1c(C)c(sc1N)C(=O)Nc2ccccc2F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P09 compound treatment 611050.0 389000.0 0.8 569117.0 337000.0 0.73 1.0835 0.9989 1390584 CBMicro_000627 Cc1cc(nc2cc(nn12)C(=O)Nc3ccc(Cl)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P10 compound treatment 589203.0 367000.0 0.76 566175.0 334000.0 0.72 1.0471 0.9997 1923583 CBMicro_000628 Cc1ccc(o1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P11 compound treatment 596247.0 374000.0 0.77 571770.0 340000.0 0.74 1.066 0.9997 1555779 CBMicro_000629 CCOC(=O)c1nc[nH]c1C(=O)NCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P12 compound treatment 582985.0 361000.0 0.74 563257.0 331000.0 0.72 1.0336 0.9998 1923584 CBMicro_000630 COc1ccc(cc1[N+](=O)[O-])C(=O)n2c(C)nc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P13 compound treatment 590006.0 368000.0 0.76 561060.0 329000.0 0.71 1.0405 0.9995 1139096 CBMicro_000631 COc1ccccc1OCC(=O)Nc2ccc(Nc3ccccc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P14 compound treatment 566717.0 344000.0 0.71 583535.0 352000.0 0.76 1.0409 0.9994 1923585 CBMicro_000632 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P15 compound treatment 573200.0 351000.0 0.72 579147.0 347000.0 0.75 1.0436 0.9998 1285248 CBMicro_000633 COc1ccc2NC(C)(C)c3sn(c4ccc(OC)c(OC)c4)c(=S)c3-c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P16 compound treatment 581282.0 359000.0 0.74 595997.0 364000.0 0.79 1.0812 0.9995 1579622 CBMicro_000634 Fc1ccccc1C(=O)NCc2ccc3OCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P17 compound treatment 588001.0 366000.0 0.75 601491.0 370000.0 0.8 1.0994 0.9996 1781612 CBMicro_000635 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P18 compound treatment 569866.0 347000.0 0.72 592873.0 361000.0 0.78 1.0597 0.9991 1574330 CBMicro_000636 COc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4ccc(F)cc4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P19 compound treatment 560715.0 338000.0 0.7 590385.0 359000.0 0.78 1.0426 0.9986 1215827 CBMicro_000637 CCOc1ccc(cc1OCC)C(=O)N2CCC(Cc3ccccc3)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P20 compound treatment 548094.0 326000.0 0.67 572904.0 341000.0 0.74 0.9974 0.9989 1126726 CBMicro_000638 CN(C)c1cccc(c1)C(=O)Nc2ccncc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P21 compound treatment 550316.0 328000.0 0.68 582844.0 351000.0 0.76 1.0159 0.9983 1923586 CBMicro_000639 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCCC3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P22 compound treatment 542142.0 320000.0 0.66 573162.0 341000.0 0.74 0.9891 0.9984 1405479 CBMicro_000640 COc1ccc(CC(=O)NCC2CCCO2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P23 mock treatment 563681.0 341000.0 0.7 578262.0 346000.0 0.75 1.0284 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.687 P24 mock treatment 430500.0 208000.0 0.43 424521.0 193000.0 0.42 0.5987 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A01 mock treatment 15519.0 -236000.0 -0.49 16398.0 -221000.0 -0.48 -0.6839 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A02 mock treatment 16702.0 -235000.0 -0.49 16670.0 -221000.0 -0.48 -0.6818 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A03 compound treatment 662726.0 411000.0 0.85 598236.0 360000.0 0.78 1.1513 0.9991 1923587 CBMicro_000641 Cn1c(/C=C/c2ccc(o2)C(=O)c3ccccc3)nc4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A04 compound treatment 605811.0 354000.0 0.73 563632.0 326000.0 0.71 1.0152 0.9998 1260435 CBMicro_000642 CSc1ccc(cc1)C2NC(=O)c3ccccc3N2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A05 compound treatment 619622.0 368000.0 0.76 560294.0 322000.0 0.7 1.0303 0.9991 1923588 CBMicro_000643 [O-][N+](=O)c1cc(Cl)ccc1N2CCN(CC2)C(=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A06 compound treatment 637084.0 385000.0 0.8 582689.0 345000.0 0.75 1.09 0.9995 1187671 CBMicro_000644 COc1ccc(cc1)N(CC(=O)NCC2CCCO2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A07 compound treatment 648619.0 397000.0 0.82 603968.0 366000.0 0.79 1.1395 0.9999 1923589 CBMicro_000645 COCCOC(=O)c1ccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A08 compound treatment 637135.0 385000.0 0.8 599414.0 362000.0 0.78 1.1157 1.0 1923590 CBMicro_000646 Clc1cccc(/C=C/2\SC(=O)N(C2=O)c3ccccc3)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A09 compound treatment 630640.0 379000.0 0.78 584936.0 347000.0 0.75 1.0841 0.9998 1923591 CBMicro_000647 O=C1c2ccccc2C(=O)c3c(cccc13)S(=O)(=O)NNc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A10 compound treatment 647914.0 396000.0 0.82 602182.0 364000.0 0.79 1.1357 0.9998 1643770 CBMicro_000648 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)Nc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A11 compound treatment 636160.0 384000.0 0.79 597887.0 360000.0 0.78 1.112 1.0 1923592 CBMicro_000649 Brc1ccc(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A12 compound treatment 662080.0 410000.0 0.85 607370.0 370000.0 0.8 1.1643 0.9996 1923593 CBMicro_000650 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\SC(=S)N(C3=O)c4cccc(Cl)c4)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A13 compound treatment 676386.0 424000.0 0.88 599510.0 362000.0 0.78 1.1732 0.9984 1487231 CBMicro_000651 CCC(C(=O)Nc1ccccc1I)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A14 compound treatment 650000.0 398000.0 0.82 609206.0 371000.0 0.8 1.1495 0.9999 1923594 CBMicro_000652 Oc1ccc(cc1NC(=O)CN2C(=O)/C(=C/c3ccccc3)/SC2=S)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A15 compound treatment 681088.0 429000.0 0.89 607802.0 370000.0 0.8 1.1927 0.9987 1923595 CBMicro_000653 COc1ccccc1/C=C\2/SC(=S)N(Cc3ccccc3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A16 compound treatment 653287.0 401000.0 0.83 613743.0 376000.0 0.81 1.1612 1.0 1923596 CBMicro_000654 COc1ccc(/C=C\2/SC(=S)N(Cc3ccccc3)C2=O)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A17 compound treatment 672099.0 420000.0 0.87 622677.0 385000.0 0.83 1.2024 0.9998 1923597 CBMicro_000655 NC(=O)C(=O)Nc1ccc(Oc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A18 compound treatment 668034.0 416000.0 0.86 594140.0 356000.0 0.77 1.1528 0.9986 1923598 CBMicro_000656 Clc1ccc(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A19 compound treatment 660643.0 409000.0 0.84 594909.0 357000.0 0.77 1.1431 0.999 1585720 CBMicro_000657 Clc1ccc(c(Cl)c1)c2nc3ccccc3c(=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A20 compound treatment 647836.0 396000.0 0.82 583208.0 345000.0 0.75 1.1065 0.999 1432241 CBMicro_000658 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A21 compound treatment 714373.0 462000.0 0.95 645301.0 407000.0 0.88 1.2987 0.9992 1923599 CBMicro_000659 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(C)n(c3C)c4ccccc4)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A22 compound treatment 633014.0 381000.0 0.79 555403.0 318000.0 0.69 1.0423 0.9977 1923600 CBMicro_000660 OC(=O)CN1C(=O)/C(=C/c2ccccc2OCc3ccc(cc3)[N+](=O)[O-])/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A23 mock treatment 591943.0 340000.0 0.7 551212.0 313000.0 0.68 0.976 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 A24 mock treatment 284002.0 32100.0 0.07 222428.0 -15400.0 -0.03 0.0233 0.3143 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B01 mock treatment 15445.0 -236000.0 -0.49 16545.0 -221000.0 -0.48 -0.6838 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B02 mock treatment 18576.0 -233000.0 -0.48 16786.0 -221000.0 -0.48 -0.6789 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B03 compound treatment 700879.0 449000.0 0.93 626245.0 388000.0 0.84 1.2498 0.9988 1923601 CBMicro_000661 COC(=O)c1ccc(/C=C/2\SC(=S)N(C2=O)c3cccc(C)c3C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B04 compound treatment 671095.0 419000.0 0.87 622865.0 385000.0 0.83 1.2012 0.9998 1718553 CBMicro_000662 COc1cc2ccccc2cc1C(=O)Nc3ccc(Cl)c(NC(=O)c4ccccc4)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B05 compound treatment 1124093.0 872000.0 1.8 970162.0 732000.0 1.59 2.3939 0.998 1923602 CBMicro_000663 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C/c3ccc(I)o3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B06 compound treatment 687532.0 436000.0 0.9 628532.0 391000.0 0.85 1.2338 0.9995 1923603 CBMicro_000664 Clc1ccc(cc1Cl)S(=O)(=O)NCc2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B07 compound treatment 720528.0 469000.0 0.97 650547.0 413000.0 0.89 1.3157 0.9992 1923604 CBMicro_000665 COc1cc(/C=C/2\SC(=S)N(C2=O)c3ccc(cc3)[N+](=O)[O-])ccc1OC(=O)C4(C[C@H]5C[C@@H]6C[C@H](C5)C4)C6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B08 compound treatment 719213.0 467000.0 0.96 646698.0 409000.0 0.89 1.3079 0.9991 1923605 CBMicro_000666 CCOC(=O)c1cc(ccc1Cl)c2ccc(C=C3C(=O)N(C)C(=O)N(C)C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B09 compound treatment 719625.0 468000.0 0.97 673352.0 436000.0 0.94 1.3493 0.9999 1923606 CBMicro_000667 [O-][N+](=O)c1ccc(COc2ccccc2/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B10 compound treatment 711350.0 459000.0 0.95 648737.0 411000.0 0.89 1.2995 0.9995 1923607 CBMicro_000668 Cc1cccc(C(=O)O)c1NC(=O)c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B11 compound treatment 718885.0 467000.0 0.96 656129.0 418000.0 0.91 1.3218 0.9995 1261828 CBMicro_000669 Cc1cc(C)c(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)C(=O)Nc5c(C)cc(C)cc5C)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B12 compound treatment 703592.0 452000.0 0.93 661749.0 424000.0 0.92 1.3081 1.0 1557176 CBMicro_000670 Brc1cc(NC(=O)c2cc3ccccc3o2)ccc1NC(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B13 compound treatment 740719.0 489000.0 1.01 672142.0 434000.0 0.94 1.3782 0.9994 1007834 CBMicro_000671 CCOC(=O)CNc1cccc(NCC(=O)OCC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B14 compound treatment 721449.0 470000.0 0.97 661055.0 423000.0 0.92 1.3331 0.9996 1161648 CBMicro_000672 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B15 compound treatment 738854.0 487000.0 1.01 677341.0 440000.0 0.95 1.3835 0.9996 1923608 CBMicro_000673 CCN(CC)C(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B16 compound treatment 712069.0 460000.0 0.95 666571.0 429000.0 0.93 1.3279 0.9999 1780724 CBMicro_000674 CCOc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc(o4)[N+](=O)[O-])cc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B17 compound treatment 735519.0 484000.0 1.0 678149.0 440000.0 0.95 1.3798 0.9997 1562434 CBMicro_000675 CC(=O)Oc1ccc(C)cc1N2C(=O)c3ccc(cc3C2=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B18 compound treatment 716638.0 465000.0 0.96 651457.0 414000.0 0.9 1.3114 0.9994 1923609 CBMicro_000676 CCOC(=O)CSc1nnc(o1)c2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B19 compound treatment 715713.0 464000.0 0.96 663423.0 426000.0 0.92 1.3284 0.9998 1923610 CBMicro_000677 Cc1ccccc1C(=O)Nc2cccc(NC(=O)c3ccc(o3)[N+](=O)[O-])c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B20 compound treatment 693570.0 442000.0 0.91 632694.0 395000.0 0.85 1.249 0.9995 1923611 CBMicro_000678 CC(C)CCSc1nc2ccccc2[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B21 compound treatment 710900.0 459000.0 0.95 649230.0 411000.0 0.89 1.2996 0.9995 1593877 CBMicro_000679 COc1ccc2oc(=O)c(cc2c1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B22 compound treatment 686642.0 435000.0 0.9 612193.0 374000.0 0.81 1.2075 0.9987 1923612 CBMicro_000680 Cc1ccccc1C(=O)Nc2ccc(cn2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B23 mock treatment 692475.0 441000.0 0.91 617545.0 380000.0 0.82 1.2242 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 B24 mock treatment 243309.0 -8610.0 -0.02 282085.0 44300.0 0.1 0.0552 0.5663 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C01 mock treatment 15225.0 -237000.0 -0.49 16105.0 -222000.0 -0.48 -0.6848 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C02 mock treatment 16471.0 -235000.0 -0.49 16702.0 -221000.0 -0.48 -0.6821 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C03 compound treatment 704002.0 452000.0 0.93 626769.0 389000.0 0.84 1.2552 0.9987 1923613 CBMicro_000681 Cn1cc(cc1c2nc3ccccc3n2C)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C04 compound treatment 692564.0 441000.0 0.91 630347.0 393000.0 0.85 1.244 0.9994 1923614 CBMicro_000682 COC(=O)C1=C(C)N/C(=C/c2cccc(Br)c2)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C05 compound treatment 701174.0 449000.0 0.93 649619.0 412000.0 0.89 1.286 0.9998 1923615 CBMicro_000683 CC(=O)c1cccc(NC(=O)Cn2cnc(n2)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C06 compound treatment 703900.0 452000.0 0.93 663150.0 425000.0 0.92 1.3107 1.0 1406740 CBMicro_000684 COc1cc(ccc1OC(=O)C)C(=S)N2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C07 compound treatment 719154.0 467000.0 0.96 682562.0 445000.0 0.96 1.3627 1.0 1923616 CBMicro_000685 CC1=N/C(=C/c2ccc(OCc3ccc(Cl)cc3)cc2)/C(=O)O1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C08 compound treatment 716851.0 465000.0 0.96 666028.0 428000.0 0.93 1.334 0.9998 1923617 CBMicro_000686 CCOc1ccc(cc1)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C09 compound treatment 749113.0 497000.0 1.03 696609.0 459000.0 0.99 1.4279 0.9999 1440506 CBMicro_000687 CCN(CC)C(=O)c1cc(nc2ccccc12)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C10 compound treatment 703807.0 452000.0 0.93 658655.0 421000.0 0.91 1.3037 0.9999 1923618 CBMicro_000688 OCCN(CC#CCC(O)(c1ccccc1)c2ccccc2)Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C11 compound treatment 747685.0 496000.0 1.02 728914.0 491000.0 1.06 1.4753 0.9998 1923619 CBMicro_000689 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C12 compound treatment 724487.0 473000.0 0.98 688675.0 451000.0 0.98 1.3798 1.0 1923620 CBMicro_000690 Cc1nn(C(=O)CN2C(=O)c3ccccc3C2=O)c(C)c1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C13 compound treatment 774403.0 522000.0 1.08 730028.0 492000.0 1.07 1.516 1.0 1923621 CBMicro_000691 CCC(C(=O)Nc1ccc(Br)cc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C14 compound treatment 727639.0 476000.0 0.98 688483.0 451000.0 0.98 1.3841 1.0 1698355 CBMicro_000692 O=C(N1CCCC1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C15 compound treatment 762327.0 510000.0 1.05 704727.0 467000.0 1.01 1.4596 0.9998 1536354 CBMicro_000693 CCOc1ccccc1NC(=O)c2ccc(OC)cc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C16 compound treatment 737351.0 485000.0 1.0 697853.0 460000.0 1.0 1.4127 1.0 1522397 CBMicro_000694 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C17 compound treatment 765271.0 513000.0 1.06 725598.0 488000.0 1.06 1.4959 1.0 1923622 CBMicro_000695 COC(=O)C/1=C(C)N(CC(C)C)C(=O)\C1=C/c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C18 compound treatment 728436.0 477000.0 0.98 682606.0 445000.0 0.96 1.3763 0.9999 1436906 CBMicro_000696 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C19 compound treatment 740440.0 489000.0 1.01 701403.0 464000.0 1.0 1.4226 1.0 1923623 CBMicro_000697 OCCCNC(=O)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C20 compound treatment 722599.0 471000.0 0.97 652082.0 414000.0 0.9 1.3211 0.9992 1923624 CBMicro_000698 Clc1ccccc1COc2ccccc2/C=C/3\SC(=O)NC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C21 compound treatment 715697.0 464000.0 0.96 679649.0 442000.0 0.96 1.3532 1.0 1463330 CBMicro_000699 COC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(SC)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C22 compound treatment 715236.0 463000.0 0.96 652474.0 415000.0 0.9 1.3109 0.9995 1248495 CBMicro_000700 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2c(Cl)cccc2Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C23 mock treatment 710199.0 458000.0 0.95 661286.0 423000.0 0.92 1.3171 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 C24 mock treatment 248178.0 -3740.0 -0.01 211946.0 -25900.0 -0.06 -0.045 -0.7971 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D01 mock treatment 14911.0 -237000.0 -0.49 15519.0 -222000.0 -0.48 -0.6862 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D02 mock treatment 14429.0 -237000.0 -0.49 15812.0 -222000.0 -0.48 -0.6864 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D03 compound treatment 701847.0 450000.0 0.93 629430.0 392000.0 0.85 1.2561 0.999 1923625 CBMicro_000701 Cc1ccc(NC(=S)NC(=O)c2sc3ccccc3c2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D04 compound treatment 674457.0 423000.0 0.87 645824.0 408000.0 0.88 1.2412 1.0 1697707 CBMicro_000702 Ic1ccc(cc1)C(=O)Nc2ccc3nn(nc3c2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D05 compound treatment 689808.0 438000.0 0.9 663387.0 426000.0 0.92 1.2905 1.0 1177461 CBMicro_000703 CCN(CC)c1ccc(cc1)C(=O)Nc2ccccc2F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D06 compound treatment 675733.0 424000.0 0.87 658064.0 420000.0 0.91 1.2618 0.9998 1276687 CBMicro_000704 Cc1csc(NC(=O)c2ccco2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D07 compound treatment 697722.0 446000.0 0.92 710335.0 473000.0 1.02 1.3739 0.9986 1923626 CBMicro_000705 [O-][N+](=O)c1ccc(cc1)C(=O)/C=C/c2c[nH]c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D08 compound treatment 708016.0 456000.0 0.94 688778.0 451000.0 0.98 1.356 0.9998 1923627 CBMicro_000706 Cc1ccc(cc1C)S(=O)(=O)N/N=C/2\C(=O)Nc3ccc(Br)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D09 compound treatment 717346.0 465000.0 0.96 725566.0 488000.0 1.06 1.4259 0.9989 1923628 CBMicro_000707 CN(C)CCCNC(=O)c1c(Cl)cccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D10 compound treatment 719464.0 468000.0 0.97 707274.0 469000.0 1.02 1.401 0.9997 1469784 CBMicro_000708 COc1cccc(c1)C(=O)Nc2ccc(cc2)c3cc4ccccc4oc3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D11 compound treatment 746211.0 494000.0 1.02 744215.0 506000.0 1.1 1.4965 0.9994 1516699 CBMicro_000709 OC(=O)c1cc(NC(=O)c2ccccc2)cc(c1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D12 compound treatment 735906.0 484000.0 1.0 713818.0 476000.0 1.03 1.435 0.9999 1204576 CBMicro_000710 CCOC(=O)c1ccc(cc1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D13 compound treatment 760327.0 508000.0 1.05 733435.0 496000.0 1.07 1.5007 0.9999 1497292 CBMicro_000711 Cc1ccc(cc1C)n2c(=O)c3cc4c(=O)n(c5ccc(C)c(C)c5)c(=O)c4c(C(=O)c6ccccc6)c3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D14 compound treatment 748544.0 497000.0 1.03 704357.0 467000.0 1.01 1.439 1.0 1236579 CBMicro_000712 Cc1ccc2nc(oc2c1)c3cc(NC(=O)COc4ccccc4)ccc3OC(=O)COc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D15 compound treatment 731417.0 479000.0 0.99 715900.0 478000.0 1.03 1.4316 0.9998 1449646 CBMicro_000713 CN(C)c1cccc(c1)C(=O)Nc2ccc(Br)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D16 compound treatment 755541.0 504000.0 1.04 711681.0 474000.0 1.03 1.4604 1.0 1923629 CBMicro_000714 Cc1ccc(cc1NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(cc4)[N+](=O)[O-])C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D17 compound treatment 762291.0 510000.0 1.05 734724.0 497000.0 1.08 1.5055 0.9999 1923630 CBMicro_000715 Cc1cc(C)c(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(Sc5ccc(cc5)[N+](=O)[O-])cc4)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D18 compound treatment 712743.0 461000.0 0.95 692197.0 454000.0 0.98 1.3681 0.9999 1923631 CBMicro_000716 CC(N1C(=O)/C(=C/c2ccc(cc2)[N+](=O)[O-])/SC1=S)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D19 compound treatment 746933.0 495000.0 1.02 731189.0 493000.0 1.07 1.4777 0.9998 1923632 CBMicro_000717 COc1cc2nc(oc(=O)c2cc1OC)c3ccc(Oc4cccc(c4)c5nc6cc(OC)c(OC)cc6c(=O)o5)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D20 compound treatment 718746.0 467000.0 0.96 701317.0 464000.0 1.0 1.3908 0.9998 1923633 CBMicro_000718 COc1cccc(N/C(=N/S(=O)(=O)c2ccc(C)cc2)/Nc3nc(C)cc(C)n3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D21 compound treatment 737678.0 486000.0 1.0 710063.0 472000.0 1.02 1.4318 1.0 1430289 CBMicro_000719 COc1ccc(cc1NC(=O)c2cccc(F)c2)C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D22 compound treatment 720119.0 468000.0 0.97 681786.0 444000.0 0.96 1.3629 1.0 1458516 CBMicro_000720 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D23 mock treatment 755559.0 504000.0 1.04 683075.0 445000.0 0.96 1.4166 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 D24 mock treatment 277834.0 25900.0 0.05 207328.0 -30500.0 -0.07 -0.0088 -0.1038 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E01 mock treatment 14545.0 -237000.0 -0.49 14974.0 -223000.0 -0.48 -0.6875 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E02 mock treatment 15393.0 -237000.0 -0.49 14796.0 -223000.0 -0.48 -0.6866 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E03 compound treatment 697802.0 446000.0 0.92 632537.0 395000.0 0.85 1.255 0.9993 1599965 CBMicro_000721 Cn1c(nc2c1c3ccccc3c4ccccc24)c5ccco5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E04 compound treatment 679176.0 427000.0 0.88 628565.0 391000.0 0.85 1.2217 0.9998 1683021 CBMicro_000722 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4CCc5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E05 compound treatment 794890.0 543000.0 1.12 755914.0 518000.0 1.12 1.5855 1.0 1923634 CBMicro_000723 COc1ccc(C2=C/C(=C\c3c(OC)ccc4ccccc34)/C(=O)O2)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E06 compound treatment 679133.0 427000.0 0.88 660029.0 422000.0 0.91 1.2698 0.9998 1331408 CBMicro_000724 COc1cc(OC)c(NC(=O)c2cccc(F)c2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E07 compound treatment 741208.0 489000.0 1.01 675368.0 438000.0 0.95 1.3839 0.9995 1118405 CBMicro_000725 CCOc1cc(ccc1O)C2NC(=O)N(C)C(=C2C(=O)OCCc3ccccc3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E08 compound treatment 715772.0 464000.0 0.96 659222.0 421000.0 0.91 1.322 0.9997 1923635 CBMicro_000726 COc1ccc(/C=C\2/SC(=O)N(CNc3cc(C)ccc3C)C2=O)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E09 compound treatment 754926.0 503000.0 1.04 696484.0 459000.0 0.99 1.4362 0.9997 1170338 CBMicro_000727 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)COc4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E10 compound treatment 731478.0 480000.0 0.99 670675.0 433000.0 0.94 1.3625 0.9996 1307304 CBMicro_000728 Cc1cc(C)n(n1)C(=O)CNC(=O)COc2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E11 compound treatment 743538.0 492000.0 1.01 705541.0 468000.0 1.01 1.4335 1.0 1923636 CBMicro_000729 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CC(C)OC(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E12 compound treatment 751979.0 500000.0 1.03 711760.0 474000.0 1.03 1.4553 1.0 1170747 CBMicro_000730 CCN(CC)c1ccc(cc1)C(=O)Nc2nccs2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E13 compound treatment 746339.0 494000.0 1.02 684474.0 447000.0 0.97 1.4053 0.9996 1923637 CBMicro_000731 Clc1ccc(CNC(=O)c2ccc(Br)cc2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E14 compound treatment 750330.0 498000.0 1.03 680531.0 443000.0 0.96 1.4051 0.9994 1923638 CBMicro_000732 COc1ccc(cc1)N2C(=O)/C(=C\c3cc4OCOc4cc3[N+](=O)[O-])/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E15 compound treatment 753423.0 502000.0 1.04 702000.0 464000.0 1.0 1.4425 0.9999 1923639 CBMicro_000733 COc1ccc(/C=C/C(=O)n2nc(C)cc2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E16 compound treatment 738961.0 487000.0 1.01 716558.0 479000.0 1.04 1.4436 0.9999 1721475 CBMicro_000734 CN(C)c1ccc2C(=O)N(C)C(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E17 compound treatment 758397.0 506000.0 1.05 712001.0 474000.0 1.03 1.465 1.0 1393703 CBMicro_000735 COc1ccc(CC(=O)N2CCC(Cc3ccccc3)CC2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E18 compound treatment 745174.0 493000.0 1.02 691092.0 453000.0 0.98 1.4137 0.9998 1923640 CBMicro_000736 CCCOCc1ccc(O)c2ncccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E19 compound treatment 743464.0 492000.0 1.01 688774.0 451000.0 0.98 1.4077 0.9998 1923641 CBMicro_000737 O=C/1N(Cc2ccccc2)C(=S)S\C1=C\c3ccsc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E20 compound treatment 720528.0 469000.0 0.97 682591.0 445000.0 0.96 1.3647 1.0 1507213 CBMicro_000738 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(Br)cc2F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E21 compound treatment 747003.0 495000.0 1.02 687052.0 449000.0 0.97 1.4102 0.9997 1923642 CBMicro_000739 CCOc1cccc2C(=C3SC(=C(S3)C(=O)OC)C(=O)OC)C(=S)C(C)(C)N(C(=O)c4ccc(OC)cc4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E22 compound treatment 726872.0 475000.0 0.98 657685.0 420000.0 0.91 1.3359 0.9993 1923643 CBMicro_000740 COc1cc(ccc1NC(=O)c2cccc(F)c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E23 mock treatment 728915.0 477000.0 0.98 657318.0 420000.0 0.91 1.3383 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 E24 mock treatment 289290.0 37400.0 0.08 220700.0 -17100.0 -0.04 0.0284 0.3316 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F01 mock treatment 14367.0 -238000.0 -0.49 14744.0 -223000.0 -0.48 -0.6881 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F02 mock treatment 14398.0 -238000.0 -0.49 14367.0 -223000.0 -0.48 -0.6887 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F03 compound treatment 704954.0 453000.0 0.94 649016.0 411000.0 0.89 1.2906 0.9997 1923644 CBMicro_000741 COC(=O)C1=C(C)NC(=S)NC1c2cccs2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F04 compound treatment 687576.0 436000.0 0.9 651870.0 414000.0 0.9 1.2696 1.0 1486489 CBMicro_000742 Cc1c(cccc1n2c(=O)c3cc4c(=O)n(c5cccc(C(=O)O)c5C)c(=O)c4cc3c2=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F05 compound treatment 720366.0 468000.0 0.97 686637.0 449000.0 0.97 1.3707 1.0 1923645 CBMicro_000743 COCCNC(=O)c1ccc(NC(=O)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F06 compound treatment 676557.0 425000.0 0.88 694174.0 456000.0 0.99 1.3183 0.9982 1923646 CBMicro_000744 C/C(=C(/C#N)\C(=O)N)/NCCc1ccccc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F07 compound treatment 736704.0 485000.0 1.0 753247.0 515000.0 1.12 1.4965 0.9985 1923647 CBMicro_000745 Cc1cc(ccc1[N+](=O)[O-])c2ccc(C=C3C(=O)NC(=O)NC3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F08 compound treatment 927263.0 675000.0 1.39 698767.0 461000.0 1.0 1.6913 0.9865 1923648 CBMicro_000746 COc1ccc(NC(=O)CSCCc2ccccn2)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F09 compound treatment 722637.0 471000.0 0.97 716547.0 479000.0 1.04 1.4198 0.9995 1642159 CBMicro_000747 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F10 compound treatment 737194.0 485000.0 1.0 716521.0 479000.0 1.04 1.441 0.9999 1430677 CBMicro_000748 COc1ccc(NC(=O)c2ccc(OC(=O)C)cc2)cc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F11 compound treatment 851262.0 599000.0 1.24 723819.0 486000.0 1.05 1.6187 0.9967 1923649 CBMicro_000749 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2ccc3oc(nc3c2)c4cccc5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F12 compound treatment 759196.0 507000.0 1.05 704317.0 467000.0 1.01 1.4544 0.9998 1707743 CBMicro_000750 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(N)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F13 compound treatment 738559.0 487000.0 1.0 731539.0 494000.0 1.07 1.466 0.9995 1923650 CBMicro_000751 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F14 compound treatment 728910.0 477000.0 0.98 710738.0 473000.0 1.02 1.4201 0.9998 1295944 CBMicro_000752 Cc1cc(Cl)ccc1OCC(=O)NC2CC(C)(C)NC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F15 compound treatment 753671.0 502000.0 1.04 723499.0 486000.0 1.05 1.4757 1.0 1699752 CBMicro_000753 COc1cc(NC(=O)c2cccc(F)c2)c(OC)cc1NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F16 compound treatment 729564.0 478000.0 0.99 707414.0 470000.0 1.02 1.4159 0.9999 1478613 CBMicro_000754 COC(=O)c1ccccc1NC(=O)c2cc(OC(=O)C)cc(c2)C(=O)Nc3ccccc3C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F17 compound treatment 753229.0 501000.0 1.03 733948.0 496000.0 1.07 1.4911 0.9998 1459698 CBMicro_000755 O=C(Nc1ccc(NC(=O)c2ccc3ccccc3c2)cc1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F18 compound treatment 690775.0 439000.0 0.91 710167.0 472000.0 1.02 1.3635 0.9982 1923651 CBMicro_000756 Cc1ccc(cc1)N2C3=[N+](CC2(O)c4cccc(c4)[N+](=O)[O-])CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F19 compound treatment 749469.0 498000.0 1.03 729625.0 492000.0 1.06 1.479 0.9998 1395083 CBMicro_000757 CCc1ccc2oc(nc2c1)c3cccc(NC(=O)c4ccccc4C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F20 compound treatment 725855.0 474000.0 0.98 715932.0 478000.0 1.03 1.4235 0.9996 1923652 CBMicro_000758 FC(F)(F)c1nc2ccccc2n1CC(=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F21 compound treatment 756026.0 504000.0 1.04 755328.0 518000.0 1.12 1.5279 0.9993 1923653 CBMicro_000759 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F22 compound treatment 746587.0 495000.0 1.02 682794.0 445000.0 0.96 1.4031 0.9996 1923654 CBMicro_000760 COc1ccc(cc1[N+](=O)[O-])C(=O)n2cnc3cc(C)c(C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F23 mock treatment 703997.0 452000.0 0.93 684547.0 447000.0 0.97 1.3436 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 F24 mock treatment 227444.0 -24500.0 -0.05 221653.0 -16200.0 -0.03 -0.0604 -0.9838 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G01 mock treatment 15079.0 -237000.0 -0.49 14754.0 -223000.0 -0.48 -0.6871 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G02 mock treatment 14628.0 -237000.0 -0.49 14335.0 -223000.0 -0.48 -0.6884 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G03 compound treatment 705268.0 453000.0 0.94 644302.0 406000.0 0.88 1.2839 0.9995 1923655 CBMicro_000761 CC(Nc1cc(ccc1[N+](=O)[O-])N2CCN(C)CC2)C3(C[C@H]4C[C@@H]5C[C@H](C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G04 compound treatment 807399.0 555000.0 1.15 742365.0 505000.0 1.09 1.583 0.9997 1923656 CBMicro_000762 COc1cc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G05 compound treatment 726664.0 475000.0 0.98 668362.0 431000.0 0.93 1.3519 0.9997 1217772 CBMicro_000763 CCOC(=O)c1c(C)nc2ccc(Cl)cc2c1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G06 compound treatment 714072.0 462000.0 0.95 658659.0 421000.0 0.91 1.3187 0.9997 1376482 CBMicro_000764 CCOc1ccc(cc1OCC)C(=O)N2CC(C)OC(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G07 compound treatment 730144.0 478000.0 0.99 676936.0 439000.0 0.95 1.3701 0.9998 1131673 CBMicro_000765 CCN1C(=C(C(NC1=O)c2ccc(Br)cc2)C(=O)OCC=C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G08 compound treatment 729741.0 478000.0 0.99 670246.0 432000.0 0.94 1.3593 0.9997 1452732 CBMicro_000766 Cc1ccc(cc1N2C(=O)C3C4CC(C=C4)C3C2=O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G09 compound treatment 746674.0 495000.0 1.02 704995.0 467000.0 1.01 1.4372 1.0 1923657 CBMicro_000767 CC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G10 compound treatment 741009.0 489000.0 1.01 707305.0 470000.0 1.02 1.4325 1.0 1923658 CBMicro_000768 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)NC3=NCCS3)C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G11 compound treatment 766201.0 514000.0 1.06 695825.0 458000.0 0.99 1.4517 0.9994 1653727 CBMicro_000769 COc1cc(NC(=O)CC(c2ccccc2)c3ccccc3)c(OC)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G12 compound treatment 724656.0 473000.0 0.98 683810.0 446000.0 0.97 1.3726 1.0 1923659 CBMicro_000770 [O-][N+](=O)c1ccc(COc2ccccc2/C=C/3\SC(=N)NC3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G13 compound treatment 765987.0 514000.0 1.06 703510.0 466000.0 1.01 1.4631 0.9997 1468359 CBMicro_000771 Cc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G14 compound treatment 759782.0 508000.0 1.05 716766.0 479000.0 1.04 1.4743 1.0 1923660 CBMicro_000772 OC(=O)CN1C(=O)/C(=C\c2ccc(OCc3ccccc3)cc2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G15 compound treatment 772437.0 521000.0 1.07 713111.0 475000.0 1.03 1.4872 0.9998 1923661 CBMicro_000773 COc1ccc(cc1)N2C(=O)/C(=C\c3ccsc3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G16 compound treatment 726516.0 475000.0 0.98 720200.0 482000.0 1.04 1.431 0.9995 1652669 CBMicro_000774 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NC(C(C)C)C(=O)Nc3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G17 compound treatment 770169.0 518000.0 1.07 714971.0 477000.0 1.03 1.4868 0.9998 1294540 CBMicro_000775 CCOC(=O)C1CCN(CC1)C(=O)CC(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G18 compound treatment 738768.0 487000.0 1.01 676899.0 439000.0 0.95 1.3827 0.9996 1488446 CBMicro_000776 COc1ccc(Cl)cc1NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G19 compound treatment 800806.0 549000.0 1.13 697147.0 459000.0 0.99 1.5042 0.9979 1923662 CBMicro_000777 COc1ccc(OC)c(c1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G20 compound treatment 718730.0 467000.0 0.96 691156.0 453000.0 0.98 1.3752 1.0 1536389 CBMicro_000778 NC(=O)c1cc(NC(=O)c2cccc(F)c2)c(Cl)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G21 compound treatment 766955.0 515000.0 1.06 693625.0 456000.0 0.99 1.4494 0.9993 1923663 CBMicro_000779 Cc1ccc2cc(ccc2c1)C3=C/C(=C/c4ccccn4)/C(=O)O3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G22 compound treatment 765890.0 514000.0 1.06 726030.0 488000.0 1.06 1.4974 1.0 1923664 CBMicro_000780 COc1cc(/C=C/2\SC(=S)N(C)C2=O)ccc1OC(=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G23 mock treatment 727398.0 475000.0 0.98 656143.0 418000.0 0.91 1.3343 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 G24 mock treatment 244953.0 -6970.0 -0.01 198480.0 -39300.0 -0.09 -0.0704 -0.815 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H01 mock treatment 14377.0 -238000.0 -0.49 14555.0 -223000.0 -0.48 -0.6884 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H02 mock treatment 14011.0 -238000.0 -0.49 14231.0 -224000.0 -0.48 -0.6894 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H03 compound treatment 676804.0 425000.0 0.88 651610.0 414000.0 0.9 1.2535 0.9999 1923665 CBMicro_000781 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(NC(=O)c3ccccc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H04 compound treatment 674476.0 423000.0 0.87 664135.0 426000.0 0.92 1.2693 0.9996 1923666 CBMicro_000782 [O-][N+](=O)c1ccc(Oc2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H05 compound treatment 705536.0 454000.0 0.94 667110.0 429000.0 0.93 1.3192 1.0 1923667 CBMicro_000783 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H06 compound treatment 666281.0 414000.0 0.86 646200.0 408000.0 0.88 1.2299 0.9999 1923668 CBMicro_000784 Cc1cccc2sc(NC(=O)/C=C\C(=O)O)nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H07 compound treatment 710722.0 459000.0 0.95 685009.0 447000.0 0.97 1.3541 0.9999 1299978 CBMicro_000785 COC(=O)CNC(=O)c1ccc(NC(=O)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H08 compound treatment 704789.0 453000.0 0.93 654634.0 417000.0 0.9 1.299 0.9998 1923669 CBMicro_000786 CCCc1ccc(OCCNc2ccc([N+](=O)[O-])c3cccnc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H09 compound treatment 691661.0 440000.0 0.91 700441.0 463000.0 1.0 1.3499 0.9988 1285113 CBMicro_000787 COc1ccc(OC)c(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(Cl)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H10 compound treatment 725817.0 474000.0 0.98 665986.0 428000.0 0.93 1.3471 0.9996 1289444 CBMicro_000788 Cc1ccccc1C(=O)Nc2cccc(Oc3ccc4C(=O)N(C(=O)c4c3)c5ccccc5)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H11 compound treatment 734166.0 482000.0 1.0 702869.0 465000.0 1.01 1.4157 1.0 1923670 CBMicro_000789 CC1=C(C(NC(=S)N1)c2ccccc2F)C(=O)Nc3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H12 compound treatment 711267.0 459000.0 0.95 733786.0 496000.0 1.07 1.4296 0.9981 1125473 CBMicro_000790 O=C(Nc1ccc-2c(Cc3ccccc32)c1)c4cc5ccccc5o4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H13 compound treatment 726582.0 475000.0 0.98 721400.0 484000.0 1.05 1.433 0.9995 1741389 CBMicro_000791 CCC(=O)Nc1ccc(cc1)c2nc3ccccc3o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H14 compound treatment 706771.0 455000.0 0.94 683834.0 446000.0 0.97 1.3466 0.9999 1923671 CBMicro_000792 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=O)NC2c3ccccc3Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H15 compound treatment 737098.0 485000.0 1.0 726729.0 489000.0 1.06 1.4565 0.9996 1923672 CBMicro_000793 O=C/1N(Cc2ccccc2)/C(=N/Cc3ccccc3)/S\C1=C/c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H16 compound treatment 732294.0 480000.0 0.99 697782.0 460000.0 1.0 1.4052 1.0 1923673 CBMicro_000794 O=c1n(/N=C/c2ccccn2)cnc3scc(c4ccccc4)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H17 compound treatment 739766.0 488000.0 1.01 725658.0 488000.0 1.06 1.4587 0.9997 1257942 CBMicro_000795 COc1cccc(c1)C(=O)Nc2ccc(Br)cc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H18 compound treatment 712943.0 461000.0 0.95 723683.0 486000.0 1.05 1.4166 0.9988 1923674 CBMicro_000796 COc1cc(/C=C/2\S\C(=N/C(=O)C)\NC2=O)cc(Br)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H19 compound treatment 724162.0 472000.0 0.97 730863.0 493000.0 1.07 1.4439 0.999 1923675 CBMicro_000797 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2cccc(Oc3ccc4C(=O)N(C(=O)c4c3)c5ccccc5)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H20 compound treatment 715740.0 464000.0 0.96 679333.0 442000.0 0.96 1.3528 1.0 1923676 CBMicro_000798 [O-][N+](=O)c1ccc(Cn2cc(c3ccc(Cl)c(Cl)c3)[n+]4CCCc24)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H21 compound treatment 712117.0 460000.0 0.95 695920.0 458000.0 0.99 1.3729 0.9998 1627442 CBMicro_000799 Brc1ccc(NC(=O)CNC(=O)OCc2ccccc2)c(c1)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H22 compound treatment 680814.0 429000.0 0.89 1746474.0 1510000.0 3.27 2.935 0.8675 1923677 CBMicro_000800 COc1ccc(OC(C)C(=O)Nc2ccc(cc2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H23 mock treatment 690543.0 439000.0 0.91 670554.0 433000.0 0.94 1.3026 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 H24 mock treatment 188395.0 -63500.0 -0.13 268881.0 31100.0 0.07 -0.0452 -0.3064 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I01 mock treatment 15037.0 -237000.0 -0.49 14450.0 -223000.0 -0.48 -0.6876 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I02 mock treatment 14147.0 -238000.0 -0.49 14000.0 -224000.0 -0.48 -0.6896 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I03 compound treatment 699512.0 448000.0 0.92 647983.0 410000.0 0.89 1.2811 0.9998 1923678 CBMicro_000801 Cc1cccc(c1)C(=O)Oc2ccc(/C=C\3/SC(=S)N(C3=O)c4ccccc4)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I04 compound treatment 702762.0 451000.0 0.93 641369.0 404000.0 0.87 1.2757 0.9995 1923679 CBMicro_000802 Cc1cc(ccc1c2ccc(/C=C/3\SC(=S)N(CC=C)C3=O)o2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I05 compound treatment 841590.0 590000.0 1.22 803179.0 565000.0 1.22 1.726 1.0 1923680 CBMicro_000803 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1OC(=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I06 compound treatment 708843.0 457000.0 0.94 647657.0 410000.0 0.89 1.2942 0.9995 1923681 CBMicro_000804 CCOc1ccc(cc1)N(CC(=O)NCCSc2ccccc2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I07 compound treatment 749084.0 497000.0 1.03 695008.0 457000.0 0.99 1.4254 0.9998 1605201 CBMicro_000805 COc1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I08 compound treatment 744525.0 493000.0 1.02 667678.0 430000.0 0.93 1.3769 0.999 1468992 CBMicro_000806 Clc1cccc(Cl)c1C(=O)NCc2cccnc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I09 compound treatment 729647.0 478000.0 0.99 685719.0 448000.0 0.97 1.3828 1.0 1353463 CBMicro_000807 CCC1CCc2c(C#N)c(NC(=O)CCC(=O)O)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I10 compound treatment 1169297.0 917000.0 1.89 1307168.0 1070000.0 2.31 2.9757 0.995 1923682 CBMicro_000808 Cc1ccccc1/C=C\2/SC(=NC2=O)Nc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I11 compound treatment 759071.0 507000.0 1.05 693700.0 456000.0 0.99 1.438 0.9996 1923683 CBMicro_000809 CCOc1ccc(cc1OCC)C(=O)Nc2ccc(cc2)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I12 compound treatment 700527.0 449000.0 0.93 656514.0 419000.0 0.91 1.2956 0.9999 1423271 CBMicro_000810 CCN(CC)c1ccc(cc1)C(=O)n2cnc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I13 compound treatment 783729.0 532000.0 1.1 728547.0 491000.0 1.06 1.5273 0.9999 1923684 CBMicro_000811 OC(=O)c1cccc(NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I14 compound treatment 756512.0 505000.0 1.04 682616.0 445000.0 0.96 1.4173 0.9992 1472382 CBMicro_000812 Cc1cc(C)c(NC(=O)CN2C(=O)c3ccccc3C2=O)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I15 compound treatment 768525.0 517000.0 1.07 707803.0 470000.0 1.02 1.4734 0.9997 1923685 CBMicro_000813 CCOc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1OCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I16 compound treatment 730177.0 478000.0 0.99 687096.0 449000.0 0.97 1.3857 1.0 1244837 CBMicro_000814 Clc1ccc(NC(=O)Nc2nnc(s2)c3ccccc3Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I17 compound treatment 913371.0 661000.0 1.37 852029.0 614000.0 1.33 1.9056 0.9999 1923686 CBMicro_000815 Nc1ccc(cc1)C(=O)/C=C/c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I18 compound treatment 742388.0 490000.0 1.01 693815.0 456000.0 0.99 1.4138 0.9999 1620456 CBMicro_000816 COc1cc(NC(=O)c2c(Cl)cccc2Cl)c(OC)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I19 compound treatment 762990.0 511000.0 1.06 730448.0 493000.0 1.07 1.5 1.0 1923687 CBMicro_000817 CCCN(CCC)CCCNC(=O)C(=O)NCc1ccco1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I20 compound treatment 806192.0 554000.0 1.14 746379.0 509000.0 1.1 1.5874 0.9998 1923688 CBMicro_000818 COc1cc(/C=C/2\C(=O)NC(=O)N(CC=C)C2=O)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I21 compound treatment 771092.0 519000.0 1.07 704475.0 467000.0 1.01 1.472 0.9996 1414009 CBMicro_000819 CCOc1ccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(OC)c(OC)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I22 compound treatment 763304.0 511000.0 1.06 736795.0 499000.0 1.08 1.5101 0.9999 1923689 CBMicro_000820 COc1cc(/C=C/2\SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I23 mock treatment 741550.0 490000.0 1.01 661101.0 423000.0 0.92 1.3625 0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 I24 mock treatment 263142.0 11200.0 0.02 254901.0 17100.0 0.04 0.0425 0.9746 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J01 mock treatment 14524.0 -237000.0 -0.49 15519.0 -222000.0 -0.48 -0.6867 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J02 mock treatment 14021.0 -238000.0 -0.49 12942.0 -225000.0 -0.49 -0.6914 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J03 compound treatment 660395.0 408000.0 0.84 652951.0 415000.0 0.9 1.2316 0.9995 1923690 CBMicro_000821 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3Cl)C2=O)/c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J04 compound treatment 671538.0 420000.0 0.87 662930.0 425000.0 0.92 1.2631 0.9995 1336611 CBMicro_000822 Oc1ccc(NC(=O)c2cccc(F)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J05 compound treatment 688051.0 436000.0 0.9 693510.0 456000.0 0.99 1.3341 0.999 1321599 CBMicro_000823 NC(=O)c1cc(NC(=O)c2cccc(F)c2)ccc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J06 compound treatment 712295.0 460000.0 0.95 672873.0 435000.0 0.94 1.3379 1.0 1923691 CBMicro_000824 CN1C(=O)N(C)C(=O)C(=Cc2ccc(o2)c3cc(ccc3O)[N+](=O)[O-])C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J07 compound treatment 702608.0 451000.0 0.93 675335.0 438000.0 0.95 1.3275 1.0 1923692 CBMicro_000825 COc1cc(ccc1NS(=O)(=O)c2ccc(F)cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J08 compound treatment 804391.0 552000.0 1.14 774862.0 537000.0 1.16 1.6284 1.0 1923693 CBMicro_000826 CN(C)c1ccc(/C=C/2\SC(=O)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J09 compound treatment 1090338.0 838000.0 1.73 1127101.0 889000.0 1.92 2.5849 0.9986 1923694 CBMicro_000827 Ic1ccc(/C=C/2\SC(=S)N(CC=C)C2=O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J10 compound treatment 695309.0 443000.0 0.92 688714.0 451000.0 0.98 1.3373 0.9995 1274489 CBMicro_000828 Cc1ccc(cc1)n2nc3ccc(NC(=O)c4cc(Cl)ccc4I)cc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J11 compound treatment 740492.0 489000.0 1.01 716016.0 478000.0 1.04 1.445 0.9999 1416418 CBMicro_000829 COc1cc(ccc1O)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J12 compound treatment 750546.0 499000.0 1.03 700873.0 463000.0 1.0 1.4365 0.9999 1923695 CBMicro_000830 Fc1ccccc1c2nc(=O)[nH]c3ccc(Cl)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J13 compound treatment 721584.0 470000.0 0.97 719691.0 482000.0 1.04 1.4231 0.9993 1923696 CBMicro_000831 Cc1ccccc1C(=O)Nc2cccc(NC(=O)c3cccc(Cl)c3)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J14 compound treatment 739868.0 488000.0 1.01 699644.0 462000.0 1.0 1.4191 1.0 1923697 CBMicro_000832 COc1ccc(cc1OC)C(=O)NCCNc2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J15 compound treatment 737465.0 486000.0 1.0 719406.0 482000.0 1.04 1.4458 0.9998 1371632 CBMicro_000833 Nc1ccc(cc1)C(=O)Nc2cccc(O)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J16 compound treatment 730476.0 479000.0 0.99 701037.0 463000.0 1.0 1.4075 1.0 1585447 CBMicro_000834 CCOc1ccc(cc1)C(=O)Nc2cc(=O)n(C)c(=O)n2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J17 compound treatment 832795.0 581000.0 1.2 800036.0 562000.0 1.22 1.7084 1.0 1923698 CBMicro_000835 Cc1ccc(/C=C/2\SC(=S)N(C2=O)c3ccc(C)c(C)c3)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J18 compound treatment 735648.0 484000.0 1.0 648084.0 410000.0 0.89 1.334 0.9983 1923699 CBMicro_000836 CN(C)/C=C\1/CCc2c([nH]c3ccccc23)C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J19 compound treatment 750174.0 498000.0 1.03 713728.0 476000.0 1.03 1.4557 1.0 1583428 CBMicro_000837 Cc1cc(NC(=O)c2ccccc2I)ccc1c3cc4ccccc4oc3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J20 compound treatment 724553.0 473000.0 0.98 694619.0 457000.0 0.99 1.389 1.0 1923700 CBMicro_000838 Clc1ccc(cc1)C(=O)CSc2nnc(Cc3ccccc3)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J21 compound treatment 723602.0 472000.0 0.97 716564.0 479000.0 1.04 1.4212 0.9995 1923701 CBMicro_000839 OC(=O)CCC(=O)N1N=C(CC1c2ccco2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J22 compound treatment 724863.0 473000.0 0.98 733624.0 496000.0 1.07 1.4492 0.9989 1923702 CBMicro_000840 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)Nc3ccccn3)C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J23 mock treatment 716856.0 465000.0 0.96 674307.0 437000.0 0.94 1.3467 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 J24 mock treatment 240712.0 -11200.0 -0.02 252241.0 14400.0 0.03 0.0057 0.1475 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K01 mock treatment 14450.0 -237000.0 -0.49 14262.0 -224000.0 -0.48 -0.6888 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K02 mock treatment 14587.0 -237000.0 -0.49 14220.0 -224000.0 -0.48 -0.6886 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K03 compound treatment 701847.0 450000.0 0.93 636807.0 399000.0 0.86 1.2674 0.9993 1923703 CBMicro_000841 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(Cl)cc3Cl)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K04 compound treatment 708926.0 457000.0 0.94 663451.0 426000.0 0.92 1.3185 0.9999 1923704 CBMicro_000842 Ic1ccccc1C(=O)Oc2ccc(/C=C/3\SC(=S)NC3=O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K05 compound treatment 728089.0 476000.0 0.98 668904.0 431000.0 0.93 1.3548 0.9997 1923705 CBMicro_000843 C=CCN1C(=O)/C(=C\c2ccc(OCc3ccccc3)cc2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K06 compound treatment 683093.0 431000.0 0.89 623147.0 385000.0 0.83 1.2191 0.9995 1157231 CBMicro_000844 CCN(CC)c1ccc(cc1)C(=O)Nc2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K07 compound treatment 739884.0 488000.0 1.01 677721.0 440000.0 0.95 1.3855 0.9996 1923706 CBMicro_000845 Oc1cccc(c1)C(=O)NCCNC(=O)c2cccc(O)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K08 compound treatment 706393.0 454000.0 0.94 646045.0 408000.0 0.88 1.2882 0.9996 1331173 CBMicro_000846 CCN(CC)c1ccc(cc1)C(=O)Nc2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K09 compound treatment 733897.0 482000.0 0.99 695013.0 457000.0 0.99 1.4033 1.0 1923707 CBMicro_000847 CCOc1cc(/C=C\2/SC(=S)N(CC)C2=O)ccc1OCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K10 compound treatment 692783.0 441000.0 0.91 616755.0 379000.0 0.82 1.2235 0.9987 1923708 CBMicro_000848 COc1cccc(c1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K11 compound treatment 756175.0 504000.0 1.04 672774.0 435000.0 0.94 1.4018 0.9987 1145335 CBMicro_000849 CC(=O)Nc1ccc(cc1)C(=O)N2CCc3ccccc3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K12 compound treatment 714574.0 463000.0 0.96 660413.0 423000.0 0.91 1.3221 0.9998 1197215 CBMicro_000850 COc1ccc(cc1NC(=O)c2cccc(F)c2)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K13 compound treatment 765138.0 513000.0 1.06 680550.0 443000.0 0.96 1.4267 0.9987 1923709 CBMicro_000851 Cc1nnc(NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K14 compound treatment 753560.0 502000.0 1.04 670563.0 433000.0 0.94 1.3946 0.9987 1923710 CBMicro_000852 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(Sc5ccc(cc5)[N+](=O)[O-])cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K15 compound treatment 771715.0 520000.0 1.07 699948.0 462000.0 1.0 1.466 0.9994 1923711 CBMicro_000853 COc1ccc(cc1)N2C(=O)/C(=C\c3cccc(c3)C(F)(F)F)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K16 compound treatment 717746.0 466000.0 0.96 678188.0 440000.0 0.95 1.3539 1.0 1365108 CBMicro_000854 COc1ccc(OC)c(c1)S(=O)(=O)NCc2ccccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K17 compound treatment 789460.0 538000.0 1.11 704743.0 467000.0 1.01 1.4993 0.9989 1592394 CBMicro_000855 COc1cccc(c1)C(=O)Nc2ccc(cc2)c3cnc(nc3)c4ccc(NC(=O)c5cccc(OC)c5)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K18 compound treatment 715931.0 464000.0 0.96 669688.0 432000.0 0.93 1.3383 0.9999 1711288 CBMicro_000856 COc1cc(C=O)cc(Br)c1OCc2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K19 compound treatment 757939.0 506000.0 1.04 697409.0 460000.0 0.99 1.442 0.9997 1222907 CBMicro_000857 CC(C)c1nccn1S(=O)(=O)c2cc(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K20 compound treatment 721768.0 470000.0 0.97 677179.0 439000.0 0.95 1.3583 1.0 1923712 CBMicro_000858 Cc1ccc(cc1N2C(=O)c3ccc(cc3C2=O)C(=O)c4cccc(c4)[N+](=O)[O-])C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K21 compound treatment 913916.0 662000.0 1.37 711875.0 474000.0 1.03 1.6918 0.99 1923713 CBMicro_000859 COc1ccc(/C=C\2/SC(=S)N(C2=O)c3cccc(Cl)c3)c4ccccc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K22 compound treatment 705299.0 453000.0 0.94 662667.0 425000.0 0.92 1.312 1.0 1628096 CBMicro_000860 COc1cccc(NC(=O)c2c(Cl)cccc2Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K23 mock treatment 734059.0 482000.0 1.0 655715.0 418000.0 0.9 1.3434 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 K24 mock treatment 261498.0 9580.0 0.02 281855.0 44100.0 0.1 0.0814 0.836 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L01 mock treatment 14471.0 -237000.0 -0.49 13958.0 -224000.0 -0.48 -0.6892 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L02 mock treatment 13477.0 -238000.0 -0.49 13246.0 -225000.0 -0.49 -0.6917 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L03 compound treatment 685447.0 434000.0 0.89 678202.0 440000.0 0.95 1.3068 0.9995 1501828 CBMicro_000861 Nc1ncc(Cc2ccc(Cl)c(Cl)c2)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L04 compound treatment 661939.0 410000.0 0.85 639469.0 402000.0 0.87 1.2132 0.9999 1923714 CBMicro_000862 COc1ccc(cc1Br)C(=O)Nc2ccc3nn(nc3c2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L05 compound treatment 680411.0 428000.0 0.88 666898.0 429000.0 0.93 1.2822 0.9997 1923715 CBMicro_000863 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3cccc(F)c3)c4c(OC)cccc24)S1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L06 compound treatment 666585.0 415000.0 0.86 654612.0 417000.0 0.9 1.2432 0.9997 1550220 CBMicro_000864 CC1(C)Cc2c(sc3ncn4nc(CSc5nc6ccccc6o5)nc4c23)C(C)(C)N1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L07 compound treatment 696996.0 445000.0 0.92 677231.0 439000.0 0.95 1.3222 0.9999 1663814 CBMicro_000865 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCC2CCCO2)Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L08 compound treatment 687767.0 436000.0 0.9 662894.0 425000.0 0.92 1.2868 0.9999 1923716 CBMicro_000866 [O-][N+](=O)c1ccc(NC(=O)C(c2ccccc2)c3ccccc3)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L09 compound treatment 712243.0 460000.0 0.95 691725.0 454000.0 0.98 1.3666 0.9999 1673043 CBMicro_000867 CCOC(=O)c1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L10 compound treatment 716734.0 465000.0 0.96 663108.0 425000.0 0.92 1.3294 0.9998 1923717 CBMicro_000868 CCN(CC)C(=S)SCC(=O)Nc1cc(C)ccc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L11 compound treatment 724329.0 472000.0 0.98 679644.0 442000.0 0.96 1.3658 1.0 1923718 CBMicro_000869 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cc(OC)ccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L12 compound treatment 710100.0 458000.0 0.95 673549.0 436000.0 0.94 1.3357 1.0 1481675 CBMicro_000870 Nc1nc(cs1)c2ccc3OCOc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L13 compound treatment 698686.0 447000.0 0.92 691478.0 454000.0 0.98 1.3465 0.9995 1675788 CBMicro_000871 Clc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L14 compound treatment 725032.0 473000.0 0.98 672073.0 434000.0 0.94 1.3552 0.9998 1603450 CBMicro_000872 COc1cc(NC(=O)c2ccccc2I)ccc1NC(=O)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L15 compound treatment 753007.0 501000.0 1.03 746638.0 509000.0 1.1 1.5102 0.9995 1923719 CBMicro_000873 Oc1ccc(/C=C/2\SC(=S)N(Cc3ccccc3)C2=O)cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L16 compound treatment 710994.0 459000.0 0.95 678402.0 441000.0 0.95 1.3444 1.0 1923720 CBMicro_000874 CCCOC(=O)c1cccc(NC(=O)/C=C/c2ccc(OC)c(Br)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L17 compound treatment 710769.0 459000.0 0.95 701281.0 463000.0 1.0 1.3791 0.9996 1719123 CBMicro_000875 Cc1ccc(NC(=O)c2cc(NC(=O)c3ccccc3)cc(NC(=O)c4ccccc4)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L18 compound treatment 702644.0 451000.0 0.93 668687.0 431000.0 0.93 1.3174 1.0 1923721 CBMicro_000876 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(Br)cc2C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L19 compound treatment 730907.0 479000.0 0.99 705644.0 468000.0 1.01 1.4152 0.9999 1923722 CBMicro_000877 Oc1ccc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(cc4)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L20 compound treatment 714235.0 462000.0 0.95 677464.0 440000.0 0.95 1.3477 1.0 1292888 CBMicro_000878 Clc1cccc(c1)N2C(=C)c3ccccc3NC2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L21 compound treatment 755163.0 503000.0 1.04 701459.0 464000.0 1.0 1.4442 0.9999 1229300 CBMicro_000879 OC(=O)c1ccc(C=c2sc3=NCCn3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L22 compound treatment 702915.0 451000.0 0.93 678283.0 440000.0 0.95 1.3324 0.9999 1923723 CBMicro_000880 Cn1c(NC(=O)c2ccc(cc2Cl)[N+](=O)[O-])cc(=O)n(C)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L23 mock treatment 723775.0 472000.0 0.97 657744.0 420000.0 0.91 1.3315 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 L24 mock treatment 224512.0 -27400.0 -0.06 187966.0 -49800.0 -0.11 -0.1163 -0.9546 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M01 mock treatment 14052.0 -238000.0 -0.49 14293.0 -224000.0 -0.48 -0.6893 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M02 mock treatment 14168.0 -238000.0 -0.49 12408.0 -225000.0 -0.49 -0.692 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M03 compound treatment 700924.0 449000.0 0.93 624175.0 386000.0 0.84 1.2467 0.9987 1232470 CBMicro_000881 Fc1ccccc1C(=O)Nc2nc(c(s2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M04 compound treatment 678207.0 426000.0 0.88 728310.0 491000.0 1.06 1.3729 0.9957 1923724 CBMicro_000882 COc1ccc(OC)c(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(c4)[N+](=O)[O-])c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M05 compound treatment 708385.0 456000.0 0.94 660910.0 423000.0 0.92 1.3138 0.9999 1777749 CBMicro_000883 Cc1c(Br)c(nn1CC(=O)NCc2cccs2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M06 compound treatment 754024.0 502000.0 1.04 683684.0 446000.0 0.97 1.4153 0.9994 1923725 CBMicro_000884 COc1cc(/C=C/2\SC(=S)N(CC(=O)O)C2=O)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M07 compound treatment 717544.0 466000.0 0.96 664748.0 427000.0 0.92 1.3331 0.9998 1094448 CBMicro_000885 CCOC(=O)c1c(C)c(C)sc1NC(=S)NCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M08 compound treatment 771338.0 519000.0 1.07 655091.0 417000.0 0.9 1.3968 0.9964 1923726 CBMicro_000886 CCOc1ccc(cc1OCC)C(=O)Nc2ncc(s2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M09 compound treatment 717437.0 466000.0 0.96 667908.0 430000.0 0.93 1.3378 0.9999 1545432 CBMicro_000887 CN(c1ccc(cc1)C(=O)O)S(=O)(=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M10 compound treatment 681372.0 429000.0 0.89 635001.0 397000.0 0.86 1.2348 0.9999 1542486 CBMicro_000888 COc1ccc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccccc4c5ccccc5)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M11 compound treatment 734188.0 482000.0 1.0 675576.0 438000.0 0.95 1.3739 0.9997 1500163 CBMicro_000889 COc1ccccc1N2CCN(CC2)C(=O)c3c(Cl)cccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M12 compound treatment 696488.0 445000.0 0.92 645993.0 408000.0 0.88 1.2736 0.9998 1228115 CBMicro_000890 COc1ccccc1CC(=O)N2CCc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M13 compound treatment 726625.0 475000.0 0.98 685014.0 447000.0 0.97 1.3774 1.0 1923727 CBMicro_000891 COc1ccc(cc1OC)C2CC(=NN2C(=O)c3ccccc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M14 compound treatment 729388.0 477000.0 0.99 709301.0 471000.0 1.02 1.4186 0.9998 1923728 CBMicro_000892 C/C(=N\OCc1nc2c3c4CC(C)(C)NC(C)(C)c4sc3ncn2n1)/c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M15 compound treatment 788802.0 537000.0 1.11 681473.0 444000.0 0.96 1.4627 0.9974 1923729 CBMicro_000893 FC(F)(F)c1cccc(/C=C\2/SC(=S)N(C2=O)c3cccc(Cl)c3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M16 compound treatment 732033.0 480000.0 0.99 673056.0 435000.0 0.94 1.3669 0.9997 1726263 CBMicro_000894 CCOC(=O)c1ccc(NC(=O)CCNC(=O)c2ccccc2NC(=O)c3ccc(OC)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M17 compound treatment 741904.0 490000.0 1.01 685836.0 448000.0 0.97 1.4009 0.9998 1340720 CBMicro_000895 Cc1cc(NC(=O)C(c2ccccc2)c3ccccc3)no1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M18 compound treatment 803481.0 552000.0 1.14 684465.0 447000.0 0.97 1.4887 0.9967 1923730 CBMicro_000896 O=C(Nc1ccc(/C=C/C(=O)c2ccco2)cc1)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M19 compound treatment 745842.0 494000.0 1.02 707185.0 469000.0 1.02 1.4393 1.0 1639533 CBMicro_000897 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2ccc(Cl)cc2Cl)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M20 compound treatment 753765.0 502000.0 1.04 662266.0 424000.0 0.92 1.3822 0.9982 1923731 CBMicro_000898 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCc3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M21 compound treatment 755801.0 504000.0 1.04 685320.0 448000.0 0.97 1.4204 0.9994 1923732 CBMicro_000899 FC(F)(F)c1cccc(/C=C\2/SC(=S)N(C2=O)c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M22 compound treatment 705108.0 453000.0 0.94 647531.0 410000.0 0.89 1.2886 0.9996 1548394 CBMicro_000900 COC(=O)c1ccccc1N(Cc2ccccc2)S(=O)(=O)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M23 mock treatment 747014.0 495000.0 1.02 668686.0 431000.0 0.93 1.3821 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 M24 mock treatment 212554.0 -39400.0 -0.08 371346.0 134000.0 0.29 0.1469 0.4893 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N01 mock treatment 14178.0 -238000.0 -0.49 14754.0 -223000.0 -0.48 -0.6884 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N02 mock treatment 13204.0 -239000.0 -0.49 13812.0 -224000.0 -0.48 -0.6913 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N03 compound treatment 660888.0 409000.0 0.84 636064.0 398000.0 0.86 1.2065 0.9999 1582901 CBMicro_000901 Clc1ccc(cc1)S(=O)(=O)NCC(N2CCN(CCC#N)CC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N04 compound treatment 653189.0 401000.0 0.83 635189.0 397000.0 0.86 1.1939 0.9998 1780265 CBMicro_000902 [O-][N+](=O)c1cccc(c1)C(=O)Nc2ccc(Cc3ccncc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N05 compound treatment 670270.0 418000.0 0.86 671193.0 433000.0 0.94 1.2739 0.9991 1923733 CBMicro_000903 OC(=O)[C@@H]1CC=CC[C@@H]1C(=O)Nc2cccc(F)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N06 compound treatment 645967.0 394000.0 0.81 624704.0 387000.0 0.84 1.1673 0.9999 1586756 CBMicro_000904 Cc1cc(I)ccc1S(=O)(=O)N2CCN(CC2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N07 compound treatment 684028.0 432000.0 0.89 671875.0 434000.0 0.94 1.2951 0.9997 1144762 CBMicro_000905 Cc1ccc(cc1N2C(=O)c3ccc(cc3C2=O)S(=O)(=O)c4ccc(cc4)C(=O)O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N08 compound treatment 660273.0 408000.0 0.84 637909.0 400000.0 0.87 1.2084 0.9999 1923734 CBMicro_000906 [O-][N+](=O)c1cccc(c1)C(=O)Nc2cccc(Oc3ccc4C(=O)N(C(=O)c4c3)c5ccccc5)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N09 compound treatment 700940.0 449000.0 0.93 668029.0 430000.0 0.93 1.3139 1.0 1923735 CBMicro_000907 Cc1c(C)c(ccc1[N+](=O)[O-])c2ccc(C=O)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N10 compound treatment 663473.0 412000.0 0.85 654949.0 417000.0 0.9 1.2392 0.9995 1389076 CBMicro_000908 O=C(Nc1ccccc1)c2ccccc2C(=O)N3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N11 compound treatment 702445.0 451000.0 0.93 670475.0 433000.0 0.94 1.3198 1.0 1923736 CBMicro_000909 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc2ccc(cc2)c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N12 compound treatment 658521.0 407000.0 0.84 652077.0 414000.0 0.9 1.2275 0.9995 1678639 CBMicro_000910 Cc1ccc(cc1C)S(=O)(=O)N2CCC(Cc3ccccc3)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N13 compound treatment 707585.0 456000.0 0.94 669656.0 432000.0 0.93 1.3261 1.0 1923737 CBMicro_000911 OC(=O)/C=C/C(=O)Nc1ccc(cc1)C2(c3ccccc3-c4ccccc42)c5ccc(NC(=O)\C=C\C(=O)O)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N14 compound treatment 687742.0 436000.0 0.9 671491.0 434000.0 0.94 1.2999 0.9998 1134870 CBMicro_000912 CCOC(=O)c1c(NC(=O)C(C)Oc2ccc(OC)cc2)sc3CC(C)CCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N15 compound treatment 711822.0 460000.0 0.95 669382.0 432000.0 0.93 1.3318 1.0 1392348 CBMicro_000913 CC(N1C(=O)c2ccccc2C1=O)C(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N16 compound treatment 687674.0 436000.0 0.9 668339.0 431000.0 0.93 1.295 0.9998 1923738 CBMicro_000914 [O-][N+](=O)c1ccc(Cl)c(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N17 compound treatment 704290.0 452000.0 0.93 679200.0 441000.0 0.96 1.3359 0.9999 1923739 CBMicro_000915 COc1ccc(NC(=O)c2ccc(Br)o2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N18 compound treatment 700141.0 448000.0 0.93 690192.0 452000.0 0.98 1.3466 0.9996 1923740 CBMicro_000916 CCOc1ccc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)c(OCC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N19 compound treatment 737549.0 486000.0 1.0 685964.0 448000.0 0.97 1.3948 0.9999 1923741 CBMicro_000917 CC(=O)Nc1ccc(cc1)S(=O)(=O)NN2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N20 compound treatment 738463.0 487000.0 1.0 660883.0 423000.0 0.92 1.3577 0.9989 1383837 CBMicro_000918 COc1ccc2nc(NC(=O)CN3C(=O)c4ccccc4C3=O)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N21 compound treatment 724416.0 472000.0 0.98 677255.0 439000.0 0.95 1.3623 0.9999 1923742 CBMicro_000919 CC(=O)NC1C(OCCOc2ccc(Cl)cc2Cl)OC(COC(=O)C)C(OC(=O)C)C1OC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N22 compound treatment 682437.0 431000.0 0.89 693296.0 455000.0 0.99 1.3255 0.9987 1676069 CBMicro_000920 Clc1ccc(Cl)c(c1)N2C(=O)CC(Sc3nnc[nH]3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N23 mock treatment 715283.0 463000.0 0.96 649318.0 412000.0 0.89 1.3062 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 N24 mock treatment 399347.0 147000.0 0.3 378027.0 140000.0 0.3 0.4298 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O01 mock treatment 14953.0 -237000.0 -0.49 15162.0 -223000.0 -0.48 -0.6866 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O02 mock treatment 15979.0 -236000.0 -0.49 13895.0 -224000.0 -0.48 -0.6871 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O03 compound treatment 678827.0 427000.0 0.88 626330.0 389000.0 0.84 1.2178 0.9997 1781531 CBMicro_000921 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2nc(c(s2)c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O04 compound treatment 672798.0 421000.0 0.87 586803.0 349000.0 0.76 1.1485 0.9976 1245832 CBMicro_000922 CCN(CC)c1ccc(cc1)C(=O)Nc2cccc(F)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O05 compound treatment 727332.0 475000.0 0.98 660933.0 423000.0 0.92 1.3415 0.9994 1923743 CBMicro_000923 Cc1c(Cl)cccc1NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O06 compound treatment 643374.0 391000.0 0.81 597639.0 360000.0 0.78 1.1221 0.9998 1284637 CBMicro_000924 CCOc1ccccc1NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O07 compound treatment 694263.0 442000.0 0.91 640067.0 402000.0 0.87 1.2613 0.9997 1503193 CBMicro_000925 CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O08 compound treatment 674368.0 422000.0 0.87 617588.0 380000.0 0.82 1.1979 0.9996 1601234 CBMicro_000926 CC(=O)Nc1ccccc1C(=O)N2CCC(Cc3ccccc3)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O09 compound treatment 700751.0 449000.0 0.93 631895.0 394000.0 0.85 1.2583 0.9991 1207014 CBMicro_000927 Cc1cc(C)n(CC(=O)n2c3ccccc3c4ccccc24)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O10 compound treatment 681955.0 430000.0 0.89 622432.0 385000.0 0.83 1.2164 0.9995 1923744 CBMicro_000928 COc1cc(/C=C/2\SC(=S)N(C)C2=O)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O11 compound treatment 689615.0 438000.0 0.9 689458.0 452000.0 0.98 1.3301 0.9992 1781595 CBMicro_000929 COC(=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)N2CCc3ccccc3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O12 compound treatment 615312.0 363000.0 0.75 615784.0 378000.0 0.82 1.1089 0.9991 1923745 CBMicro_000930 Cc1ccccc1/C=C/2\S/C(=N\Cc3ccccc3)/N(Cc4ccccc4)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O13 compound treatment 702844.0 451000.0 0.93 630532.0 393000.0 0.85 1.2593 0.999 1565277 CBMicro_000931 CC(Oc1ccccc1)C(=O)Nc2cc(Cl)cc(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O14 compound treatment 697359.0 445000.0 0.92 614932.0 377000.0 0.82 1.2274 0.9982 1923746 CBMicro_000932 Clc1cccc(c1)c2ncnn2c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O15 compound treatment 708203.0 456000.0 0.94 652637.0 415000.0 0.9 1.3009 0.9997 1156068 CBMicro_000933 CCOc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)Cc4ccc(F)cc4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O16 compound treatment 696052.0 444000.0 0.92 634341.0 397000.0 0.86 1.2552 0.9995 1923747 CBMicro_000934 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCCC(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O17 compound treatment 699735.0 448000.0 0.92 664075.0 426000.0 0.92 1.3061 1.0 1703406 CBMicro_000935 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C(=S)N3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O18 compound treatment 666488.0 415000.0 0.86 613318.0 376000.0 0.81 1.1798 0.9997 1923748 CBMicro_000936 Cc1nnc(NC(=O)c2cccc(F)c2)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O19 compound treatment 707351.0 455000.0 0.94 633958.0 396000.0 0.86 1.2711 0.9989 1166155 CBMicro_000937 O=C(COc1nc2ccccc2s1)n3c4ccccc4c5ccccc35 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O20 compound treatment 705665.0 454000.0 0.94 615524.0 378000.0 0.82 1.2404 0.9977 1182182 CBMicro_000938 COc1ccc(cc1)C(=O)N2C(C)CC(N(C(=O)c3cccs3)c4ccccc4)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O21 compound treatment 719711.0 468000.0 0.97 658574.0 421000.0 0.91 1.3268 0.9996 1923749 CBMicro_000939 FC(F)(F)c1cccc(c1)N2C(=O)/C(=C\c3ccsc3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O22 compound treatment 692798.0 441000.0 0.91 618023.0 380000.0 0.82 1.2255 0.9987 1923750 CBMicro_000940 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(OC)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O23 mock treatment 712412.0 460000.0 0.95 621882.0 384000.0 0.83 1.26 0.9978 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 O24 mock treatment 293510.0 41600.0 0.09 391996.0 154000.0 0.33 0.2967 0.861 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P01 mock treatment 14597.0 -237000.0 -0.49 15456.0 -222000.0 -0.48 -0.6867 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P02 mock treatment 15257.0 -237000.0 -0.49 14995.0 -223000.0 -0.48 -0.6865 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P03 compound treatment 597306.0 345000.0 0.71 569301.0 331000.0 0.72 1.0115 1.0 1159939 CBMicro_000941 COc1cccc(OC)c1C(=O)NCC2(CC3CC4C2)CC(CNC(=O)c5c(OC)cccc5OC)(C3)C4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P04 compound treatment 595269.0 343000.0 0.71 560545.0 323000.0 0.7 0.9951 1.0 1405602 CBMicro_000942 COc1ccc(OC)c(c1)S(=O)(=O)n2c(C)nc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P05 compound treatment 592077.0 340000.0 0.7 561487.0 324000.0 0.7 0.9919 1.0 1127833 CBMicro_000943 COC(=O)c1ccccc1NC(=O)c2c(Cl)cccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P06 compound treatment 613665.0 362000.0 0.75 581191.0 343000.0 0.74 1.0536 1.0 1490007 CBMicro_000944 COc1cc(F)ccc1S(=O)(=O)n2cnc3cc(C)c(C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P07 compound treatment 616736.0 365000.0 0.75 573786.0 336000.0 0.73 1.0467 0.9998 1480322 CBMicro_000945 CCN(CC)c1ccc(cc1)C(=O)Nc2ccc(Cl)c(Cl)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P08 compound treatment 617861.0 366000.0 0.76 578290.0 340000.0 0.74 1.0553 0.9999 1553214 CBMicro_000946 CCOc1ccc(Nc2nc(cs2)c3cccnc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P09 compound treatment 632177.0 380000.0 0.78 583419.0 346000.0 0.75 1.084 0.9997 1923751 CBMicro_000947 CCCC(=O)Nc1ccc(NC(=O)c2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P10 compound treatment 657555.0 406000.0 0.84 616602.0 379000.0 0.82 1.1718 0.9999 1683870 CBMicro_000948 COc1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccccc4I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P11 compound treatment 615583.0 364000.0 0.75 575755.0 338000.0 0.73 1.0481 0.9999 1923752 CBMicro_000949 OC(=O)c1ccccc1NC(=O)CN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P12 compound treatment 621354.0 369000.0 0.76 586696.0 349000.0 0.76 1.0732 1.0 1923753 CBMicro_000950 COC(=S)N/C(=N/S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P13 compound treatment 622697.0 371000.0 0.77 580772.0 343000.0 0.74 1.0661 0.9999 1923754 CBMicro_000951 CC1CN(CCN1C(=O)c2ccc(F)cc2)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P14 compound treatment 632620.0 381000.0 0.79 571899.0 334000.0 0.72 1.067 0.9991 1923755 CBMicro_000952 Brc1ccc(NC2=NC(=O)CS2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P15 compound treatment 628770.0 377000.0 0.78 586714.0 349000.0 0.76 1.0841 0.9999 1565191 CBMicro_000953 OC(=O)c1ccc(Oc2ccc(NC(=O)c3cccc(F)c3)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P16 compound treatment 645409.0 393000.0 0.81 588022.0 350000.0 0.76 1.1104 0.9994 1923756 CBMicro_000954 O=C(CCCN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P17 compound treatment 641608.0 390000.0 0.8 589128.0 351000.0 0.76 1.1065 0.9996 1923757 CBMicro_000955 COc1ccc(OC)c(/C=C/C(=O)Nc2ccc(C)c(Cl)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P18 compound treatment 627177.0 375000.0 0.77 629738.0 392000.0 0.85 1.1476 0.999 1611288 CBMicro_000956 CCOc1cc(ccc1O)C(=S)N2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P19 compound treatment 645769.0 394000.0 0.81 618059.0 380000.0 0.82 1.1569 1.0 1262258 CBMicro_000957 Cc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccc(Br)cc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P20 compound treatment 657892.0 406000.0 0.84 581478.0 344000.0 0.74 1.1186 0.9982 1923758 CBMicro_000958 Cc1ccc(OCCOc2ccc(C=O)cc2)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P21 compound treatment 642184.0 390000.0 0.81 578533.0 341000.0 0.74 1.0911 0.999 1923759 CBMicro_000959 Brc1ccc(NC(=O)CNC(=O)CNC(=O)OCc2ccccc2)c(c1)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P22 compound treatment 645095.0 393000.0 0.81 593902.0 356000.0 0.77 1.1189 0.9997 1136253 CBMicro_000960 Cc1cc(C)n(n1)C(=O)CNC(=O)c2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P23 mock treatment 640033.0 388000.0 0.8 596008.0 358000.0 0.78 1.1147 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.688 P24 mock treatment 417002.0 165000.0 0.34 426500.0 189000.0 0.41 0.5298 0.996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A01 mock treatment 15414.0 -226000.0 -0.47 14786.0 -217000.0 -0.47 -0.6624 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A02 mock treatment 17833.0 -224000.0 -0.46 17194.0 -215000.0 -0.46 -0.6552 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A03 compound treatment 694478.0 453000.0 0.94 541923.0 310000.0 0.67 1.1356 0.9867 1923760 CBMicro_000961 O=C(/C=C/c1cn(nc1c2ccccc2)c3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A04 compound treatment 591975.0 350000.0 0.72 542340.0 310000.0 0.67 0.9866 0.9993 1923761 CBMicro_000962 CN1CCN(CC1)C(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A05 compound treatment 615143.0 374000.0 0.77 570837.0 339000.0 0.73 1.064 0.9997 1536804 CBMicro_000963 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A06 compound treatment 619010.0 378000.0 0.78 581289.0 349000.0 0.76 1.0856 0.9999 1314591 CBMicro_000964 COc1ccc(cc1)C(O)c2coc3ccc(O)c(CN(C)C)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A07 compound treatment 637572.0 396000.0 0.82 587296.0 355000.0 0.77 1.1219 0.9995 1923762 CBMicro_000965 COc1ccc2nc(SC)nc(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A08 compound treatment 1167416.0 926000.0 1.91 587796.0 356000.0 0.77 1.8961 0.9201 1667538 CBMicro_000966 CC(C)c1cccc(C(C)C)c1NC(=O)COc2cc(C)c(Cl)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A09 compound treatment 640722.0 399000.0 0.82 592805.0 361000.0 0.78 1.135 0.9996 1923763 CBMicro_000967 Brc1cccc(c1)C(=O)NNc2nc(cs2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A10 compound treatment 633712.0 392000.0 0.81 619205.0 387000.0 0.84 1.1651 0.9999 1923764 CBMicro_000968 FC(F)(F)c1cccc(NC(=O)/C=C/c2cc(Br)cs2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A11 compound treatment 599813.0 358000.0 0.74 578703.0 347000.0 0.75 1.0537 1.0 1923765 CBMicro_000969 Cc1cc(ccc1NC(=O)/C=C/c2ccccc2Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A12 compound treatment 654084.0 413000.0 0.85 574815.0 343000.0 0.74 1.1269 0.9976 1740500 CBMicro_000970 CCOC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A13 compound treatment 654332.0 413000.0 0.85 575274.0 343000.0 0.74 1.128 0.9977 1408475 CBMicro_000971 CC(NC(=O)NS(=O)(=O)c1ccc(C)cc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A14 compound treatment 660698.0 419000.0 0.87 579881.0 348000.0 0.75 1.1443 0.9976 1448814 CBMicro_000972 Clc1ccc(OCc2nn(CN3CCCCC3)c(=S)o2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A15 compound treatment 653203.0 412000.0 0.85 587875.0 356000.0 0.77 1.1456 0.9988 1923766 CBMicro_000973 CCC(C)c1ccc(NC(=O)/C=C/c2cccc(c2)[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A16 compound treatment 630681.0 389000.0 0.8 604490.0 373000.0 0.81 1.1382 1.0 1676552 CBMicro_000974 Cc1nnc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A17 compound treatment 635369.0 394000.0 0.81 590606.0 359000.0 0.78 1.1238 0.9997 1923767 CBMicro_000975 Cc1ccccc1c2nc3cc(NC(=O)c4ccccc4[N+](=O)[O-])ccc3o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A18 compound treatment 626038.0 385000.0 0.79 589531.0 358000.0 0.77 1.1085 0.9999 1675423 CBMicro_000976 COc1ccc(cc1)S(=O)(=O)N(CC(=O)O)Cc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A19 compound treatment 654905.0 413000.0 0.85 597873.0 366000.0 0.79 1.1634 0.9993 1923768 CBMicro_000977 CCOc1ccccc1NC(=O)CN2C(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A20 compound treatment 642594.0 401000.0 0.83 583369.0 351000.0 0.76 1.1233 0.9991 1923769 CBMicro_000978 CCOc1ccc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A21 compound treatment 638614.0 397000.0 0.82 588280.0 356000.0 0.77 1.125 0.9995 1230867 CBMicro_000979 COc1ccc(Cl)cc1NC(=O)c2cc(Cl)ccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A22 compound treatment 608108.0 367000.0 0.76 560897.0 329000.0 0.71 1.0385 0.9995 1923770 CBMicro_000980 OC(=O)c1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A23 mock treatment 598080.0 357000.0 0.74 552772.0 321000.0 0.69 1.0114 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 A24 mock treatment 234816.0 -6680.0 -0.01 214972.0 -17000.0 -0.04 -0.0358 -0.9102 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B01 mock treatment 15341.0 -226000.0 -0.47 15592.0 -216000.0 -0.47 -0.6613 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B02 mock treatment 16629.0 -225000.0 -0.46 16587.0 -215000.0 -0.47 -0.6579 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B03 compound treatment 657537.0 416000.0 0.86 627654.0 396000.0 0.86 1.2128 1.0 1923771 CBMicro_000981 Cn1nnnc1NC(=O)c2ccccc2F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B04 compound treatment 645842.0 404000.0 0.83 617106.0 385000.0 0.83 1.1796 1.0 1923772 CBMicro_000982 CN1C(=O)/C(=C/c2ccccc2F)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B05 compound treatment 713728.0 472000.0 0.97 657802.0 426000.0 0.92 1.341 0.9996 1597460 CBMicro_000983 Cc1cc(C)nc(SCC(=O)OCC(=O)Nc2ccc(cc2)S(=O)(=O)N)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B06 compound treatment 665968.0 424000.0 0.88 607217.0 375000.0 0.81 1.1939 0.9993 1243645 CBMicro_000984 Cc1ccc(CNC(=O)CN(Cc2ccccc2)S(=O)(=O)c3ccc(C)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B07 compound treatment 691795.0 450000.0 0.93 663409.0 431000.0 0.93 1.3176 1.0 1923773 CBMicro_000985 COc1ccc(NC(=O)c2ccc(CSc3ccc(Br)cc3)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B08 compound treatment 684984.0 443000.0 0.92 633151.0 401000.0 0.87 1.2613 0.9997 1472575 CBMicro_000986 Cc1ccc(NC(=O)c2cccc(n2)C(=O)Nc3ccc(C)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B09 compound treatment 713823.0 472000.0 0.98 737188.0 505000.0 1.09 1.4626 0.9984 1518924 CBMicro_000987 Cc1ccc(NC2CC(=O)N(C2=O)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B10 compound treatment 686334.0 445000.0 0.92 651554.0 420000.0 0.91 1.2915 1.0 1923774 CBMicro_000988 COc1ccc(/C=C/C(=O)Nc2cccc(c2)[N+](=O)[O-])cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B11 compound treatment 682461.0 441000.0 0.91 644965.0 413000.0 0.89 1.2757 1.0 1923775 CBMicro_000989 COc1cccc(NC(=O)/C(=C/c2ccccc2)/c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B12 compound treatment 700350.0 459000.0 0.95 657085.0 425000.0 0.92 1.3204 0.9999 1475658 CBMicro_000990 COc1cccc(c1)C(=O)N2CCN(Cc3cc(OC)c(OC)cc3OC)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B13 compound treatment 746425.0 505000.0 1.04 690345.0 458000.0 0.99 1.4385 0.9997 1222971 CBMicro_000991 Cn1c(Sc2nc3ccccc3n2Cc4ccccc4)nc5n(C)c(=O)n(C)c(=O)c15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B14 compound treatment 933145.0 692000.0 1.43 881703.0 650000.0 1.41 2.004 1.0 1636387 CBMicro_000992 Cc1ccc(C)n1c2cc(ccc2C)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B15 compound treatment 725402.0 484000.0 1.0 671590.0 440000.0 0.95 1.3791 0.9997 1923776 CBMicro_000993 COc1ccc(Cn2c(SC)nc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B16 compound treatment 717837.0 476000.0 0.98 660399.0 428000.0 0.93 1.351 0.9996 1923777 CBMicro_000994 COc1cc(cc(OC)c1OC)C(=O)NCCOc2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B17 compound treatment 745623.0 504000.0 1.04 697163.0 465000.0 1.01 1.4478 0.9999 1374005 CBMicro_000995 Cc1ccc(NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B18 compound treatment 705675.0 464000.0 0.96 653619.0 422000.0 0.91 1.3228 0.9997 1275805 CBMicro_000996 Cc1cccc(NC(=O)COc2c(C)cc(C)cc2C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B19 compound treatment 734121.0 493000.0 1.02 703628.0 472000.0 1.02 1.4409 1.0 1285802 CBMicro_000997 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N4CCOCC4)C(=O)CC(C)(C)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B20 compound treatment 688597.0 447000.0 0.92 651826.0 420000.0 0.91 1.2952 1.0 1304019 CBMicro_000998 CC(C)CCc1c(O)nc(SCCN2CCOCC2)n(c3ccccc3)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B21 compound treatment 743601.0 502000.0 1.04 702046.0 470000.0 1.02 1.4523 1.0 1436478 CBMicro_000999 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3cccc(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B22 compound treatment 673197.0 432000.0 0.89 634654.0 403000.0 0.87 1.2464 0.9999 1923778 CBMicro_001000 COCCNC(=S)Nc1ccc(F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B23 mock treatment 662758.0 421000.0 0.87 648371.0 416000.0 0.9 1.2522 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 B24 mock treatment 208365.0 -33100.0 -0.07 219601.0 -12400.0 -0.03 -0.0673 -0.9163 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C01 mock treatment 15738.0 -226000.0 -0.47 14786.0 -217000.0 -0.47 -0.6619 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C02 mock treatment 16199.0 -225000.0 -0.47 14461.0 -218000.0 -0.47 -0.6618 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C03 compound treatment 686798.0 445000.0 0.92 637635.0 406000.0 0.88 1.2708 0.9997 1923779 CBMicro_001001 Cc1cc(C)n(n1)C(=O)CNC(=O)c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C04 compound treatment 660097.0 419000.0 0.86 663848.0 432000.0 0.93 1.272 0.9992 1923780 CBMicro_001002 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C05 compound treatment 682230.0 441000.0 0.91 659466.0 427000.0 0.93 1.2976 1.0 1923781 CBMicro_001003 O=C(CCCN1C(=O)/C(=C\c2cccs2)/SC1=S)NC3(CC4CC5CC(C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C06 compound treatment 693904.0 452000.0 0.93 656429.0 424000.0 0.92 1.31 1.0 1923782 CBMicro_001004 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)Nc3nccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C07 compound treatment 718869.0 477000.0 0.99 684625.0 453000.0 0.98 1.3896 1.0 1923783 CBMicro_001005 Cc1ccc(cc1)S(=O)(=O)/N=C(\N)/Nc2nc(C)c3ccccc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C08 compound treatment 712090.0 471000.0 0.97 665151.0 433000.0 0.94 1.3499 0.9998 1923784 CBMicro_001006 COc1ccc(cc1OC)c2cc3c(ccc4ccccc43)oc2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C09 compound treatment 735682.0 494000.0 1.02 690553.0 459000.0 0.99 1.4232 0.9999 1698830 CBMicro_001007 COc1ccc2nc(NC(=O)COc3ccc(Cl)cc3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C10 compound treatment 706311.0 465000.0 0.96 681107.0 449000.0 0.97 1.3658 1.0 1923785 CBMicro_001008 Fc1ccc(N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4cc5ccccc5oc4=O)c(F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C11 compound treatment 1301173.0 1060000.0 2.19 1237837.0 1010000.0 2.18 3.0862 1.0 1923786 CBMicro_001009 Fc1ccc(NC2=NC(=O)/C(=C/c3cccs3)/S2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C12 compound treatment 737256.0 496000.0 1.02 662835.0 431000.0 0.93 1.383 0.9989 1923787 CBMicro_001010 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2)C(=N1)O)/c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C13 compound treatment 728435.0 487000.0 1.01 675794.0 444000.0 0.96 1.39 0.9997 1365166 CBMicro_001011 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C14 compound treatment 686539.0 445000.0 0.92 658102.0 426000.0 0.92 1.3018 1.0 1923788 CBMicro_001012 COc1cccc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C15 compound treatment 749603.0 508000.0 1.05 684557.0 453000.0 0.98 1.4343 0.9994 1580796 CBMicro_001013 COc1ccc(OC(C)C(=O)Nc2ccc(C)c(Cl)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C16 compound treatment 732494.0 491000.0 1.01 686637.0 455000.0 0.98 1.4125 0.9999 1923789 CBMicro_001014 CC(C)CCNC(=O)c1ccc([N+](=O)[O-])c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C17 compound treatment 740862.0 499000.0 1.03 695525.0 464000.0 1.0 1.4383 0.9999 1320485 CBMicro_001015 CCOc1cccc(c1)C(=O)Nc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C18 compound treatment 1110818.0 869000.0 1.79 1037517.0 806000.0 1.74 2.5018 0.9999 1923790 CBMicro_001016 On1c(=O)c(c2cccs2)[n+]([O-])c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C19 compound treatment 729124.0 488000.0 1.01 685764.0 454000.0 0.98 1.4063 0.9999 1923791 CBMicro_001017 OC(=O)CCN1C(=O)/C(=C/c2cccc(OCc3ccccc3)c2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C20 compound treatment 757029.0 516000.0 1.06 713628.0 482000.0 1.04 1.4896 0.9999 1923792 CBMicro_001018 COc1cc(/C=C\2/SC(=S)N(CC(=O)Nc3cccc(c3)C(=O)O)C2=O)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C21 compound treatment 730752.0 489000.0 1.01 697939.0 466000.0 1.01 1.4273 1.0 1208900 CBMicro_001019 CC(Oc1cccc(Cl)c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)nc(C)n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C22 compound treatment 704172.0 463000.0 0.96 659276.0 427000.0 0.92 1.3293 0.9999 1923793 CBMicro_001020 OS(=O)(=O)c1ccc(/C=C\2/SC(=N)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C23 mock treatment 705278.0 464000.0 0.96 646157.0 414000.0 0.9 1.3108 0.9995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 C24 mock treatment 207464.0 -34000.0 -0.07 260179.0 28200.0 0.06 -0.0065 -0.0701 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D01 mock treatment 14670.0 -227000.0 -0.47 14806.0 -217000.0 -0.47 -0.6635 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D02 mock treatment 15288.0 -226000.0 -0.47 15131.0 -217000.0 -0.47 -0.6621 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D03 compound treatment 664112.0 423000.0 0.87 655657.0 424000.0 0.92 1.2653 0.9997 1923794 CBMicro_001021 CSc1nccn1CC(=O)Nc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D04 compound treatment 798231.0 557000.0 1.15 788874.0 557000.0 1.21 1.6649 0.9997 1923795 CBMicro_001022 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D05 compound treatment 695229.0 454000.0 0.94 709823.0 478000.0 1.03 1.3936 0.9988 1132275 CBMicro_001023 Oc1ccc2occ(C(=O)C3CC3)c2c1CN4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D06 compound treatment 674967.0 433000.0 0.89 659469.0 427000.0 0.93 1.287 0.9999 1256598 CBMicro_001024 Clc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)COc3ccc4ccccc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D07 compound treatment 698323.0 457000.0 0.94 703505.0 472000.0 1.02 1.3885 0.9992 1923796 CBMicro_001025 COc1ccc(C)cc1NC(=O)C(=O)NCCc2ccc(OC)c(OC)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D08 compound treatment 722394.0 481000.0 0.99 684893.0 453000.0 0.98 1.3951 1.0 1923797 CBMicro_001026 O=C1NC(=O)/C(=C/c2ccc(OCCOc3ccccc3)cc2)/C(=O)N1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D09 compound treatment 731600.0 490000.0 1.01 714405.0 482000.0 1.04 1.4537 0.9999 1923798 CBMicro_001027 OC1=N/C(=N/N=C/c2cccc(O)c2)/SC1CC(=O)Nc3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D10 compound treatment 684261.0 443000.0 0.91 698328.0 466000.0 1.01 1.36 0.9988 1923799 CBMicro_001028 COc1ccc(/C=C/C(=O)N(C)C2CCCCC2)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D11 compound treatment 727798.0 486000.0 1.0 747906.0 516000.0 1.12 1.4994 0.9986 1141497 CBMicro_001029 CN(C)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D12 compound treatment 719100.0 478000.0 0.99 697550.0 466000.0 1.01 1.4097 0.9999 1783409 CBMicro_001030 OC1=C(C(N(CC2CCCO2)C1=O)c3ccc(cc3)[N+](=O)[O-])C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D13 compound treatment 729036.0 488000.0 1.01 776928.0 545000.0 1.18 1.5457 0.9969 1780068 CBMicro_001031 CCSc1nc2ccccc2n1Cc3ccc(OC)c(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D14 compound treatment 719057.0 478000.0 0.99 706424.0 474000.0 1.03 1.4232 0.9998 1923800 CBMicro_001032 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)/C=C/c2ccccc2)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D15 compound treatment 702286.0 461000.0 0.95 693581.0 462000.0 1.0 1.3791 0.9997 1688742 CBMicro_001033 Cc1ccc(c2ccccc2)n1c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D16 compound treatment 724650.0 483000.0 1.0 691839.0 460000.0 1.0 1.409 1.0 1923801 CBMicro_001034 Cc1ccccc1NC(=O)C(=O)NCCCN2CCOCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D17 compound treatment 735413.0 494000.0 1.02 726363.0 494000.0 1.07 1.4776 0.9997 1923802 CBMicro_001035 COC(=O)c1ccc(cc1)n2c(C)ccc2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D18 compound treatment 672572.0 431000.0 0.89 655314.0 423000.0 0.92 1.2771 0.9999 1189947 CBMicro_001036 Cc1cc(C)c(OCC(=O)Nc2cccc3ccccc23)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D19 compound treatment 744065.0 503000.0 1.04 726183.0 494000.0 1.07 1.4899 0.9999 1494040 CBMicro_001037 CS(=O)(=O)N1CCN(CC1)C(=O)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D20 compound treatment 707232.0 466000.0 0.96 685082.0 453000.0 0.98 1.3733 1.0 1923803 CBMicro_001038 [O-][N+](=O)c1cccc(c1)C(=O)c2ccc3C(=O)N(NC(=O)c4ccco4)C(=O)c3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D21 compound treatment 728732.0 487000.0 1.01 706803.0 475000.0 1.03 1.4379 0.9999 1923804 CBMicro_001039 COc1ccccc1NC(=O)/C(=C/c2ccccc2)/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D22 compound treatment 726166.0 485000.0 1.0 709463.0 477000.0 1.03 1.4382 0.9999 1923805 CBMicro_001040 CC(=O)/N=C\1/NC(=O)/C(=C\c2ccc(cc2)C(C)(C)C)/S1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D23 mock treatment 701541.0 460000.0 0.95 662480.0 430000.0 0.93 1.3304 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 D24 mock treatment 240042.0 -1460.0 0.0 216931.0 -15100.0 -0.03 -0.0252 -0.7691 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E01 mock treatment 14806.0 -227000.0 -0.47 14681.0 -217000.0 -0.47 -0.6635 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E02 mock treatment 15330.0 -226000.0 -0.47 15047.0 -217000.0 -0.47 -0.6621 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E03 compound treatment 675582.0 434000.0 0.9 643353.0 411000.0 0.89 1.2632 1.0 1923806 CBMicro_001041 CC(C)c1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E04 compound treatment 656022.0 415000.0 0.86 615183.0 383000.0 0.83 1.1915 0.9999 1923807 CBMicro_001042 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E05 compound treatment 700228.0 459000.0 0.95 664391.0 432000.0 0.94 1.3314 1.0 1923808 CBMicro_001043 COc1ccc(Br)cc1C(=O)NCCNc2ccc(Cl)cc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E06 compound treatment 694818.0 453000.0 0.94 672957.0 441000.0 0.95 1.3366 1.0 1923809 CBMicro_001044 OC(=O)c1ccc(N/C(=N\S(=O)(=O)c2ccc(Cl)cc2)/c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E07 compound treatment 712722.0 471000.0 0.97 691939.0 460000.0 1.0 1.3918 0.9999 1658274 CBMicro_001045 NC(=O)C1CCCc2c1[nH]c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E08 compound treatment 705985.0 464000.0 0.96 666189.0 434000.0 0.94 1.3425 0.9999 1923810 CBMicro_001046 COc1ccccc1/C=C/C(=O)c2ccc(cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E09 compound treatment 724324.0 483000.0 1.0 703428.0 471000.0 1.02 1.4263 0.9999 1923811 CBMicro_001047 Cc1nc2ccc(NC(=S)Nc3cccc(c3)[N+](=O)[O-])cc2nc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E10 compound treatment 688706.0 447000.0 0.92 681527.0 450000.0 0.97 1.3408 0.9997 1923812 CBMicro_001048 CN(C1=NC(=O)/C(=C\C=C\c2ccccc2)/S1)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E11 compound treatment 751137.0 510000.0 1.05 687899.0 456000.0 0.99 1.4417 0.9995 1923813 CBMicro_001049 O=C(CCCN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3ccccn3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E12 compound treatment 711089.0 470000.0 0.97 673052.0 441000.0 0.95 1.3605 1.0 1923814 CBMicro_001050 COc1ccc(CC(=O)O/N=C(\N)/c2ccccn2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E13 compound treatment 735817.0 494000.0 1.02 688523.0 457000.0 0.99 1.4203 0.9999 1590999 CBMicro_001051 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCN(Cc3ccccc3)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E14 compound treatment 716985.0 475000.0 0.98 647940.0 416000.0 0.9 1.3307 0.9991 1669471 CBMicro_001052 O=C(N1CCc2ccccc2C1)c3cc(nc4ccccc34)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E15 compound treatment 754974.0 513000.0 1.06 685632.0 454000.0 0.98 1.4438 0.9993 1923815 CBMicro_001053 Cc1cc(OCc2nc(no2)c3ccncc3)ccc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E16 compound treatment 729267.0 488000.0 1.01 688685.0 457000.0 0.99 1.4109 1.0 1338733 CBMicro_001054 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4cc(Cl)ccc4Cl)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E17 compound treatment 759686.0 518000.0 1.07 709370.0 477000.0 1.03 1.487 0.9998 1293828 CBMicro_001055 CCCC(=O)Nc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E18 compound treatment 727677.0 486000.0 1.0 671487.0 440000.0 0.95 1.3823 0.9996 1923816 CBMicro_001056 COc1cccc(/C=C/2\SC(=S)N(C)C2=O)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E19 compound treatment 745479.0 504000.0 1.04 659244.0 427000.0 0.92 1.3896 0.9983 1923817 CBMicro_001057 Fc1ccc(N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4ccc(Cl)s4)c(F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E20 compound treatment 657148.0 416000.0 0.86 654040.0 422000.0 0.91 1.2527 0.9995 1923818 CBMicro_001058 CC(=O)C1=C(S/C(=C\2/C(=S)C(C)(C)Nc3ccccc23)/S1)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E21 compound treatment 693521.0 452000.0 0.93 692168.0 460000.0 1.0 1.3641 0.9995 1923819 CBMicro_001059 COc1ccccc1C/C(=N/OC(=O)c2ccc(Cl)cc2)/N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E22 compound treatment 672765.0 431000.0 0.89 654683.0 423000.0 0.91 1.2764 0.9999 1923820 CBMicro_001060 [O-][N+](=O)c1ccc(cc1)c2noc(CCc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E23 mock treatment 731899.0 490000.0 1.01 654345.0 422000.0 0.91 1.3622 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 E24 mock treatment 201726.0 -39800.0 -0.08 214124.0 -17900.0 -0.04 -0.0854 -0.9409 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F01 mock treatment 14377.0 -227000.0 -0.47 15005.0 -217000.0 -0.47 -0.6636 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F02 mock treatment 14775.0 -227000.0 -0.47 14419.0 -218000.0 -0.47 -0.6639 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F03 compound treatment 665876.0 424000.0 0.88 662731.0 431000.0 0.93 1.2787 0.9995 1923821 CBMicro_001061 CCC(=O)Nc1nc(C)c(s1)c2csc(Nc3ccc(cc3)N(C)C)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F04 compound treatment 664043.0 423000.0 0.87 657121.0 425000.0 0.92 1.2674 0.9996 1923822 CBMicro_001062 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F05 compound treatment 709275.0 468000.0 0.97 682350.0 450000.0 0.97 1.3721 1.0 1923823 CBMicro_001063 Clc1ccc(C(=O)Nc2nc(cs2)c3cccs3)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F06 compound treatment 691151.0 450000.0 0.93 693336.0 461000.0 1.0 1.3624 0.9993 1923824 CBMicro_001064 CC/C(=C/1\C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2)/N4CCCCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F07 compound treatment 717059.0 476000.0 0.98 705583.0 474000.0 1.03 1.419 0.9998 1335911 CBMicro_001065 O=C(Nc1cccc2ccccc12)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F08 compound treatment 697802.0 456000.0 0.94 688135.0 456000.0 0.99 1.3642 0.9997 1923825 CBMicro_001066 Oc1ccc(NC(=O)c2cccc(c2)N3C(=O)c4cccc([N+](=O)[O-])c4C3=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F09 compound treatment 757676.0 516000.0 1.07 769653.0 538000.0 1.16 1.5763 0.999 1592066 CBMicro_001067 Oc1ccccc1c2cc([nH]n2)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F10 compound treatment 699523.0 458000.0 0.95 689679.0 458000.0 0.99 1.3691 0.9997 1680843 CBMicro_001068 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F11 compound treatment 671553.0 430000.0 0.89 663140.0 431000.0 0.93 1.2876 0.9997 1923826 CBMicro_001069 CCCCOC(=O)c1cccc(NC(=O)C(C)Oc2ccc(OC)cc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F12 compound treatment 715549.0 474000.0 0.98 688194.0 456000.0 0.99 1.3902 1.0 1499074 CBMicro_001070 CS(=O)(=O)N1CCN(CCCc2ccccc2)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F13 compound treatment 835318.0 594000.0 1.23 844853.0 613000.0 1.33 1.8048 0.9992 1923827 CBMicro_001071 Cc1ccc(/C=C/2\C=C(OC2=O)c3ccc(Cl)cc3)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F14 compound treatment 730515.0 489000.0 1.01 697424.0 465000.0 1.01 1.4261 1.0 1331016 CBMicro_001072 COc1cc(N)ccc1n2c(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F15 compound treatment 728210.0 487000.0 1.0 689837.0 458000.0 0.99 1.4112 1.0 1923828 CBMicro_001073 CC(=O)c1ccc(cc1)n2c(C)ccc2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F16 compound treatment 728364.0 487000.0 1.01 703146.0 471000.0 1.02 1.4318 1.0 1923829 CBMicro_001074 COc1ccc(cc1OC)C(=O)NCCOc2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F17 compound treatment 757987.0 516000.0 1.07 734825.0 503000.0 1.09 1.5235 0.9999 1706062 CBMicro_001075 Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F18 compound treatment 739323.0 498000.0 1.03 706119.0 474000.0 1.03 1.4523 1.0 1923830 CBMicro_001076 CCOc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F19 compound treatment 792566.0 551000.0 1.14 719663.0 488000.0 1.06 1.5508 0.9993 1923831 CBMicro_001077 COc1ccc(/C=C/C(=O)Nc2ccccc2Cl)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F20 compound treatment 706136.0 465000.0 0.96 702061.0 470000.0 1.02 1.3977 0.9996 1923832 CBMicro_001078 Cc1cc(C=O)c(C)n1c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F21 compound treatment 771369.0 530000.0 1.09 704897.0 473000.0 1.02 1.4972 0.9995 1923833 CBMicro_001079 COc1ccc(/C=C/C(=O)NCC2CCCO2)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F22 compound treatment 707009.0 466000.0 0.96 699547.0 468000.0 1.01 1.3951 0.9997 1787289 CBMicro_001080 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(CC2)C(=O)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F23 mock treatment 674250.0 433000.0 0.89 693018.0 461000.0 1.0 1.3373 0.9985 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 F24 mock treatment 292599.0 51100.0 0.11 246555.0 14600.0 0.03 0.0969 0.88 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G01 mock treatment 15225.0 -226000.0 -0.47 14566.0 -217000.0 -0.47 -0.663 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G02 mock treatment 15110.0 -226000.0 -0.47 14503.0 -217000.0 -0.47 -0.6633 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G03 compound treatment 689462.0 448000.0 0.92 653995.0 422000.0 0.91 1.2998 1.0 1872843 CBMicro_001081 Cc1c(NC(=O)c2cccs2)cccc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G04 compound treatment 678012.0 437000.0 0.9 644207.0 412000.0 0.89 1.2681 1.0 1923834 CBMicro_001082 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)CCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G05 compound treatment 738350.0 497000.0 1.03 682036.0 450000.0 0.97 1.414 0.9997 1923835 CBMicro_001083 COc1cc(/C=C\2/SC(=S)N(CC(=O)NCCCN3CCOCC3)C2=O)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G06 compound treatment 694099.0 453000.0 0.93 653658.0 422000.0 0.91 1.306 0.9999 1162406 CBMicro_001084 Cc1ccc(NS(=O)(=O)c2ccc3OCCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G07 compound treatment 728743.0 487000.0 1.01 678760.0 447000.0 0.97 1.395 0.9998 1923836 CBMicro_001085 CC(CNC(=O)CN(c1ccc(C)cc1)S(=O)(=O)C)NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G08 compound treatment 714542.0 473000.0 0.98 681675.0 450000.0 0.97 1.3787 1.0 1923837 CBMicro_001086 CCOC(=O)c1ccccc1NC(=O)c2cc(Cl)ccc2[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G09 compound treatment 743143.0 502000.0 1.04 683669.0 452000.0 0.98 1.4235 0.9996 1923838 CBMicro_001087 O=C(NCc1ccco1)C(=O)N2CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G10 compound treatment 714870.0 473000.0 0.98 658192.0 426000.0 0.92 1.3433 0.9996 1923839 CBMicro_001088 FC(F)Oc1ccc(cc1)C(=O)Nc2ccccc2Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G11 compound treatment 734568.0 493000.0 1.02 682650.0 451000.0 0.98 1.4095 0.9998 1475836 CBMicro_001089 COc1ccc(OC(C)C(=O)Nc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G12 compound treatment 705531.0 464000.0 0.96 672793.0 441000.0 0.95 1.352 1.0 1446341 CBMicro_001090 Cc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(O)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G13 compound treatment 752977.0 511000.0 1.06 684596.0 453000.0 0.98 1.4393 0.9993 1923840 CBMicro_001091 Cc1ccc(cc1Cl)n2nc3ccc(NC(=O)c4cccs4)cc3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G14 compound treatment 717304.0 476000.0 0.98 680925.0 449000.0 0.97 1.3816 1.0 1923841 CBMicro_001092 Cc1n(C)c2ccccc2[n+]1Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G15 compound treatment 758194.0 517000.0 1.07 674651.0 443000.0 0.96 1.4317 0.9986 1257443 CBMicro_001093 COc1ccc(OC(C)C(=O)Nc2ccc(F)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G16 compound treatment 672634.0 431000.0 0.89 590599.0 359000.0 0.78 1.1782 0.9977 1923842 CBMicro_001094 CCCCOC(=O)c1ccc(NC(=O)c2cc(Cl)ccc2[N+](=O)[O-])cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G17 compound treatment 760123.0 519000.0 1.07 711151.0 479000.0 1.04 1.4904 0.9999 1317091 CBMicro_001095 CCC(=O)Nc1ccc(NC(=O)c2cccc(Cl)c2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G18 compound treatment 732171.0 491000.0 1.01 700370.0 468000.0 1.01 1.4331 1.0 1223395 CBMicro_001096 Cc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NCc3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G19 compound treatment 786308.0 545000.0 1.12 788223.0 556000.0 1.2 1.6465 0.9994 1359055 CBMicro_001097 CC(C)c1ccccc1NC(=O)C2C(C3CC2C=C3)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G20 compound treatment 724177.0 483000.0 1.0 661554.0 430000.0 0.93 1.362 0.9994 1923843 CBMicro_001098 COC(=O)c1ccc(C(=O)OC)c(NC(=O)/C=C/c2ccccc2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G21 compound treatment 731844.0 490000.0 1.01 695329.0 463000.0 1.0 1.4249 1.0 1188699 CBMicro_001099 Fc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G22 compound treatment 707377.0 466000.0 0.96 703223.0 471000.0 1.02 1.4012 0.9996 1923844 CBMicro_001100 OC1=N/C(=N/N=C/c2ccccc2)/SC1CC(=O)Nc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G23 mock treatment 728837.0 487000.0 1.01 691939.0 460000.0 1.0 1.4153 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 G24 mock treatment 209925.0 -31600.0 -0.07 240104.0 8120.0 0.02 -0.0337 -0.4986 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H01 mock treatment 15173.0 -226000.0 -0.47 14880.0 -217000.0 -0.47 -0.6626 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H02 mock treatment 14304.0 -227000.0 -0.47 14073.0 -218000.0 -0.47 -0.6651 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H03 compound treatment 660716.0 419000.0 0.87 659717.0 428000.0 0.93 1.2666 0.9994 1923845 CBMicro_001101 COc1ccccc1/C=C/2\C=C(OC2=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H04 compound treatment 647253.0 406000.0 0.84 643113.0 411000.0 0.89 1.2215 0.9995 1923846 CBMicro_001102 Cc1nnc(SCC(=O)Nc2nnc(s2)c3ccccc3)[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H05 compound treatment 692689.0 451000.0 0.93 673079.0 441000.0 0.95 1.3337 0.9999 1598829 CBMicro_001103 CCN1C(=O)c2cccc3c(NC(=O)c4ccc(cc4)S(=O)(=O)N(C)C)ccc1c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H06 compound treatment 669136.0 428000.0 0.88 678645.0 447000.0 0.97 1.3078 0.999 1521210 CBMicro_001104 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H07 compound treatment 649221.0 408000.0 0.84 666861.0 435000.0 0.94 1.2607 0.9984 1923847 CBMicro_001105 O=C(/C=C/c1ccc(OCc2ccccc2)cc1)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H08 compound treatment 685315.0 444000.0 0.92 650425.0 418000.0 0.91 1.2882 1.0 1923848 CBMicro_001106 Cc1cc(C=O)c(C)n1c2cccc(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H09 compound treatment 713275.0 472000.0 0.97 696498.0 465000.0 1.01 1.3996 0.9999 1203448 CBMicro_001107 CCCC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H10 compound treatment 679865.0 438000.0 0.9 670088.0 438000.0 0.95 1.3104 0.9997 1923849 CBMicro_001108 CN(C)c1ccc(/C=C/2\C(=O)c3cccc([N+](=O)[O-])c3C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H11 compound treatment 709605.0 468000.0 0.97 678722.0 447000.0 0.97 1.367 1.0 1487317 CBMicro_001109 Clc1cccc(c1)N2CCN(CC2)C(=O)Cc3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H12 compound treatment 688670.0 447000.0 0.92 698894.0 467000.0 1.01 1.3673 0.999 1374720 CBMicro_001110 COc1ccc(OC)c(COc2ccc(cc2)c3nc4sc5CCCCc5c4c(=O)[nH]3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H13 compound treatment 729140.0 488000.0 1.01 703479.0 471000.0 1.02 1.4334 1.0 1259284 CBMicro_001111 CCc1cccc(C)c1NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H14 compound treatment 854216.0 613000.0 1.26 849247.0 617000.0 1.34 1.8391 0.9996 1371747 CBMicro_001112 Cc1ccc(C)n1c2cccc(C(=O)O)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H15 compound treatment 726768.0 485000.0 1.0 687924.0 456000.0 0.99 1.4061 1.0 1711947 CBMicro_001113 CC(NC(=O)C(C)N1C(=O)c2ccccc2C1=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H16 compound treatment 714934.0 473000.0 0.98 686754.0 455000.0 0.98 1.3871 1.0 1174632 CBMicro_001114 COc1ccc(NC(=O)COc2c(C)cc(C)cc2C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H17 compound treatment 699036.0 458000.0 0.94 707492.0 476000.0 1.03 1.3956 0.9991 1275689 CBMicro_001115 O=C(Sc1nc2ccccc2[nH]1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H18 compound treatment 677849.0 436000.0 0.9 669726.0 438000.0 0.95 1.3069 0.9997 1416804 CBMicro_001116 CC(Sc1nc2ccccc2s1)C(=O)Nc3c(C)cc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H19 compound treatment 718297.0 477000.0 0.98 701832.0 470000.0 1.02 1.4151 0.9999 1923850 CBMicro_001117 COc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H20 compound treatment 728743.0 487000.0 1.01 675302.0 443000.0 0.96 1.3897 0.9997 1530620 CBMicro_001118 COc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccc(OC)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H21 compound treatment 697666.0 456000.0 0.94 708619.0 477000.0 1.03 1.3953 0.999 1923851 CBMicro_001119 Cc1cccc(n1)N2C(=O)C3CC=CCC3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H22 compound treatment 693371.0 452000.0 0.93 688105.0 456000.0 0.99 1.3577 0.9996 1686384 CBMicro_001120 Cc1cccc(C)c1OCC(=O)Nc2ccccc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H23 mock treatment 679410.0 438000.0 0.9 672977.0 441000.0 0.95 1.3141 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 H24 mock treatment 177254.0 -64200.0 -0.13 195024.0 -37000.0 -0.08 -0.1503 -0.9707 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I01 mock treatment 15519.0 -226000.0 -0.47 14670.0 -217000.0 -0.47 -0.6624 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I02 mock treatment 13791.0 -228000.0 -0.47 13309.0 -219000.0 -0.47 -0.6671 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I03 compound treatment 685642.0 444000.0 0.92 643714.0 412000.0 0.89 1.2784 0.9999 1652301 CBMicro_001121 COc1ccc(Cl)cc1C(=O)Nc2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I04 compound treatment 673949.0 432000.0 0.89 634922.0 403000.0 0.87 1.2479 0.9999 1923852 CBMicro_001122 CCOc1ccc(/C=C/C(=O)Nc2cc(ccc2C)[N+](=O)[O-])cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I05 compound treatment 705325.0 464000.0 0.96 695179.0 463000.0 1.0 1.3859 0.9997 1659081 CBMicro_001123 CC(C)(C)NC(=O)c1cc(nc2ccccc12)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I06 compound treatment 702195.0 461000.0 0.95 655830.0 424000.0 0.92 1.3211 0.9998 1923853 CBMicro_001124 Cc1ccc(cc1)C(=O)Sc2[nH]c(nc2S(=O)(=O)c3ccc(C)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I07 compound treatment 742755.0 501000.0 1.03 697626.0 466000.0 1.01 1.4443 0.9999 1923854 CBMicro_001125 CCOc1cc(C=C2C(=O)c3ccccc3C2=O)cc(Br)c1OCc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I08 compound treatment 711015.0 470000.0 0.97 663222.0 431000.0 0.93 1.3453 0.9998 1923855 CBMicro_001126 Cc1ccc(NC(=O)c2ccc(OCc3ccccc3)cc2)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I09 compound treatment 750488.0 509000.0 1.05 697364.0 465000.0 1.01 1.4552 0.9998 1492074 CBMicro_001127 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I10 compound treatment 719389.0 478000.0 0.99 677208.0 445000.0 0.96 1.379 0.9999 1706867 CBMicro_001128 CC1CCN(CC1)c2nc(nc3ccccc23)c4ccccc4O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I11 compound treatment 740315.0 499000.0 1.03 683355.0 451000.0 0.98 1.4189 0.9997 1325287 CBMicro_001129 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3c(F)cccc3F)cc2)ncn1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I12 compound treatment 735575.0 494000.0 1.02 659975.0 428000.0 0.93 1.3762 0.9988 1577584 CBMicro_001130 Cc1ccc(cc1)c2ccc(OCC(=O)Nc3nnc[nH]3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I13 compound treatment 760638.0 519000.0 1.07 706229.0 474000.0 1.03 1.4836 0.9998 1923856 CBMicro_001131 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)Nc3ccc4OCOc4c3)C2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I14 compound treatment 744634.0 503000.0 1.04 669140.0 437000.0 0.95 1.4035 0.9989 1423397 CBMicro_001132 NNC(=O)c1ccc(cc1)n2c(ccc2c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I15 compound treatment 760081.0 519000.0 1.07 699629.0 468000.0 1.01 1.4727 0.9996 1554827 CBMicro_001133 COc1ccc(OC(C)C(=O)NCCc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I16 compound treatment 729713.0 488000.0 1.01 664560.0 433000.0 0.94 1.3747 0.9993 1231089 CBMicro_001134 COc1ccc(Oc2coc3cc(OC(=O)c4ccccc4Cl)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I17 compound treatment 747021.0 506000.0 1.04 711451.0 479000.0 1.04 1.4717 1.0 1340152 CBMicro_001135 CCC(=O)Nc1ccc2oc(nc2c1)c3ccccc3Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I18 compound treatment 718810.0 477000.0 0.99 673446.0 441000.0 0.96 1.3724 0.9999 1923857 CBMicro_001136 Cc1ccc(NC(=O)c2cc(I)ccc2Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I19 compound treatment 766468.0 525000.0 1.08 748474.0 516000.0 1.12 1.5568 0.9999 1923858 CBMicro_001137 CCOc1ccc(/C=C/C(=O)NC(c2ccccc2)c3ccccc3)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I20 compound treatment 699350.0 458000.0 0.95 674472.0 442000.0 0.96 1.3455 1.0 1923859 CBMicro_001138 CCC(C(=O)Nc1cccc(Br)c1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I21 compound treatment 749887.0 508000.0 1.05 696484.0 465000.0 1.01 1.453 0.9998 1923860 CBMicro_001139 CC1CCc2c(C(=O)N)c(NC(=O)/C=C/c3ccccc3)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I22 compound treatment 717273.0 476000.0 0.98 683080.0 451000.0 0.98 1.3849 1.0 1923861 CBMicro_001140 COc1ccccc1c2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I23 mock treatment 713961.0 472000.0 0.98 663068.0 431000.0 0.93 1.3494 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 I24 mock treatment 222606.0 -18900.0 -0.04 239822.0 7840.0 0.02 -0.0156 -0.3663 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J01 mock treatment 14995.0 -227000.0 -0.47 14838.0 -217000.0 -0.47 -0.663 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J02 mock treatment 13717.0 -228000.0 -0.47 14073.0 -218000.0 -0.47 -0.666 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J03 compound treatment 663578.0 422000.0 0.87 648843.0 417000.0 0.9 1.2541 0.9998 1923862 CBMicro_001141 Nc1ccc(Nc2nc(cs2)c3ccc(Br)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J04 compound treatment 639863.0 398000.0 0.82 630924.0 399000.0 0.86 1.192 0.9997 1712078 CBMicro_001142 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J05 compound treatment 696548.0 455000.0 0.94 671267.0 439000.0 0.95 1.3365 1.0 1200299 CBMicro_001143 CCCOc1cccc(NC(=O)c2cc(C)oc2C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J06 compound treatment 681098.0 440000.0 0.91 683520.0 452000.0 0.98 1.3327 0.9993 1464711 CBMicro_001144 Brc1cccc(c1)C2CC(=O)Nc3c2cc(Br)c4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J07 compound treatment 692540.0 451000.0 0.93 682128.0 450000.0 0.97 1.3473 0.9997 1923863 CBMicro_001145 NC(=O)C(=O)Nc1cccc2ccccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J08 compound treatment 733078.0 492000.0 1.01 752057.0 520000.0 1.13 1.5135 0.9987 1923864 CBMicro_001146 CCN1C(=O)C(=Cc2ccc(o2)c3cccc(c3)C(=O)O)C(=O)N(CC)C1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J09 compound treatment 694449.0 453000.0 0.94 727754.0 496000.0 1.07 1.4199 0.9976 1923865 CBMicro_001147 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(Cl)cc3)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J10 compound treatment 690049.0 449000.0 0.93 686046.0 454000.0 0.98 1.3497 0.9996 1153029 CBMicro_001148 CCC(=O)Nc1cccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(OC)cc4)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J11 compound treatment 710094.0 469000.0 0.97 699426.0 467000.0 1.01 1.3994 0.9997 1168063 CBMicro_001149 CN(C)c1ccc(cc1)C(=O)NCc2ccc(cc2)S(=O)(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J12 compound treatment 691547.0 450000.0 0.93 673295.0 441000.0 0.96 1.3323 0.9999 1452250 CBMicro_001150 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)NCc3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J13 compound treatment 712948.0 471000.0 0.97 725871.0 494000.0 1.07 1.444 0.9989 1923866 CBMicro_001151 COC(=O)c1ccccc1NC(=O)CSc2nc[nH]n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J14 compound treatment 722416.0 481000.0 0.99 693830.0 462000.0 1.0 1.4088 1.0 1923867 CBMicro_001152 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)/C=C/c2ccccc2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J15 compound treatment 730282.0 489000.0 1.01 706648.0 475000.0 1.03 1.4399 1.0 1787294 CBMicro_001153 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCN(CC2)C(=O)c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J16 compound treatment 732644.0 491000.0 1.01 689236.0 457000.0 0.99 1.4167 0.9999 1923868 CBMicro_001154 CCc1ccccc1NC(=O)C(=O)NCc2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J17 compound treatment 742006.0 501000.0 1.03 737814.0 506000.0 1.09 1.5047 0.9996 1131101 CBMicro_001155 Cc1nc(NC(=O)c2ccccc2)sc1c3csc(Nc4cccc(c4)C(=O)O)n3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J18 compound treatment 662976.0 421000.0 0.87 677498.0 446000.0 0.96 1.2971 0.9987 1495006 CBMicro_001156 CC(C)Oc1ccccc1NC(=O)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J19 compound treatment 724167.0 483000.0 1.0 808049.0 576000.0 1.25 1.5862 0.9938 1923869 CBMicro_001157 CC(C)NC(=O)/C(=C/c1ccccc1)/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J20 compound treatment 709650.0 468000.0 0.97 721088.0 489000.0 1.06 1.4319 0.999 1923870 CBMicro_001158 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J21 compound treatment 700915.0 459000.0 0.95 712201.0 480000.0 1.04 1.4056 0.999 1923871 CBMicro_001159 Cc1cc(NC(=O)CCCOc2ccc(Cl)cc2Cl)no1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J22 compound treatment 652315.0 411000.0 0.85 682113.0 450000.0 0.97 1.2886 0.9976 1143991 CBMicro_001160 Cc1ccc(c2ccccc2)n1c3ccc(cc3)C(=O)NN 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J23 mock treatment 705412.0 464000.0 0.96 686593.0 455000.0 0.98 1.3729 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 J24 mock treatment 197359.0 -44100.0 -0.09 190867.0 -41100.0 -0.09 -0.1274 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K01 mock treatment 15005.0 -226000.0 -0.47 14157.0 -218000.0 -0.47 -0.664 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K02 mock treatment 14063.0 -227000.0 -0.47 12838.0 -219000.0 -0.47 -0.6674 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K03 compound treatment 671095.0 430000.0 0.89 643044.0 411000.0 0.89 1.2562 1.0 1470335 CBMicro_001161 COc1ccccc1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K04 compound treatment 677383.0 436000.0 0.9 624846.0 393000.0 0.85 1.2375 0.9996 1590107 CBMicro_001162 Cc1cccc(N2CCN(CC2)C(=O)Nc3ccc(Cl)cc3)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K05 compound treatment 683011.0 442000.0 0.91 648315.0 416000.0 0.9 1.2816 1.0 1229618 CBMicro_001163 COc1ccc(Cl)cc1C(=O)N2CCN(CC2)c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K06 compound treatment 692957.0 451000.0 0.93 657385.0 425000.0 0.92 1.31 1.0 1923872 CBMicro_001164 Clc1ccccc1c2ccc(/C=C/C(=O)c3ccc4ccccc4c3)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K07 compound treatment 721029.0 480000.0 0.99 676330.0 444000.0 0.96 1.38 0.9999 1284898 CBMicro_001165 Cc1ccccc1N2C(=O)CC(SC3=NCCS3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K08 compound treatment 689684.0 448000.0 0.93 732066.0 500000.0 1.08 1.4196 0.9969 1923873 CBMicro_001166 COc1cc(NC(=O)c2ccc(o2)c3cccc(c3)[N+](=O)[O-])ccc1NC(=O)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K09 compound treatment 736142.0 495000.0 1.02 692544.0 461000.0 1.0 1.4269 0.9999 1923874 CBMicro_001167 CCOC(=O)C1=C(C)N/C(=C/c2ccc(OCC)cc2)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K10 compound treatment 685501.0 444000.0 0.92 671193.0 439000.0 0.95 1.3203 0.9998 1923875 CBMicro_001168 [O-][N+](=O)c1ccc(NC(=O)N(CCCCN2C(=O)c3ccccc3C2=O)c4ccc(Cl)cc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K11 compound treatment 705970.0 464000.0 0.96 726314.0 494000.0 1.07 1.4345 0.9985 1923876 CBMicro_001169 CC(C)OP(=O)(OC(C)C)c1nc2ccccc2c(Nc3ccccc3)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K12 compound treatment 713232.0 472000.0 0.97 636739.0 405000.0 0.88 1.308 0.9986 1923877 CBMicro_001170 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2C)C(=N1)O)/c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K13 compound treatment 738090.0 497000.0 1.03 676890.0 445000.0 0.96 1.4058 0.9995 1615858 CBMicro_001171 COC(=O)c1cc(NC(=O)CCc2ccccc2)cc(c1)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K14 compound treatment 719512.0 478000.0 0.99 661635.0 430000.0 0.93 1.3553 0.9996 1923878 CBMicro_001172 [O-][N+](=O)c1cccc(c1)C2=Nn3c(Cc4ccccc4)nnc3SC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K15 compound treatment 735732.0 494000.0 1.02 675435.0 443000.0 0.96 1.4001 0.9995 1923879 CBMicro_001173 COC(=O)c1sc(NC(=O)c2cc(ccc2Cl)[N+](=O)[O-])c(C(=O)OC)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K16 compound treatment 735402.0 494000.0 1.02 702885.0 471000.0 1.02 1.4416 1.0 1577881 CBMicro_001174 COc1ccc(OC(C)C(=O)Nc2ccccc2F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K17 compound treatment 739532.0 498000.0 1.03 709087.0 477000.0 1.03 1.4572 1.0 1923880 CBMicro_001175 COc1ccc(cc1OC)C(=O)NCCCNc2ccc(cc2Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K18 compound treatment 709745.0 468000.0 0.97 676202.0 444000.0 0.96 1.3633 1.0 1551570 CBMicro_001176 CC(=O)Nc1ccc(NS(=O)(=O)Cc2ccccc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K19 compound treatment 829894.0 588000.0 1.21 819980.0 588000.0 1.27 1.7588 0.9997 1923881 CBMicro_001177 CC(C)c1ccc(/C=C/2\SC(=NC2=O)Nc3ccc(F)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K20 compound treatment 729119.0 488000.0 1.01 682181.0 450000.0 0.97 1.4008 0.9999 1298764 CBMicro_001178 CCNC(=O)N1c2ccc(OC)cc2C(=CC1(C)C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K21 compound treatment 719389.0 478000.0 0.99 701893.0 470000.0 1.02 1.4167 0.9999 1923882 CBMicro_001179 COc1ccccc1C2CC(=NN2C(=O)C)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K22 compound treatment 708988.0 467000.0 0.97 681050.0 449000.0 0.97 1.3697 1.0 1718245 CBMicro_001180 CN1CCN(Cc2c(C)nc3ccc(C)cc3c2O)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K23 mock treatment 730243.0 489000.0 1.01 701531.0 470000.0 1.02 1.432 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 K24 mock treatment 266755.0 25300.0 0.05 214742.0 -17200.0 -0.04 0.0105 0.1635 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L01 mock treatment 14628.0 -227000.0 -0.47 14314.0 -218000.0 -0.47 -0.6643 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L02 mock treatment 13026.0 -228000.0 -0.47 12063.0 -220000.0 -0.48 -0.6701 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L03 compound treatment 661046.0 420000.0 0.87 657833.0 426000.0 0.92 1.2642 0.9995 1923883 CBMicro_001181 CCC(=O)Nc1nc(C)c(s1)c2csc(Nc3cc(C)ccn3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L04 compound treatment 653534.0 412000.0 0.85 634129.0 402000.0 0.87 1.2169 0.9999 1923884 CBMicro_001182 Brc1ccc2[nH]c(=O)c(NC(=O)CN3CCOCC3)c(c4ccccc4)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L05 compound treatment 713174.0 472000.0 0.97 671590.0 440000.0 0.95 1.3613 0.9999 1214731 CBMicro_001183 O=C(CSC1=NCCS1)NCc2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L06 compound treatment 664551.0 423000.0 0.87 638953.0 407000.0 0.88 1.2404 1.0 1867285 CBMicro_001184 [O-][N+](=O)c1c(Cl)c2ccccc2n(c3ccccc3)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L07 compound treatment 690439.0 449000.0 0.93 663656.0 432000.0 0.93 1.316 1.0 1276571 CBMicro_001185 Cc1cc(C)c2sc(NC(=O)c3cccc(Cl)c3)nc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L08 compound treatment 675062.0 434000.0 0.9 653965.0 422000.0 0.91 1.2787 0.9999 1679397 CBMicro_001186 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L09 compound treatment 698767.0 457000.0 0.94 686226.0 454000.0 0.98 1.3627 0.9998 1923885 CBMicro_001187 NC(=O)c1ccccc1NC(=O)/C(=C/c2ccccc2)/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L10 compound treatment 690458.0 449000.0 0.93 666364.0 434000.0 0.94 1.3201 1.0 1923886 CBMicro_001188 Clc1cccc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L11 compound treatment 699456.0 458000.0 0.95 698692.0 467000.0 1.01 1.3827 0.9995 1923887 CBMicro_001189 Cc1ccnc(Nc2nc(cs2)c3ccc(Br)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L12 compound treatment 757950.0 516000.0 1.07 671777.0 440000.0 0.95 1.4269 0.9984 1923888 CBMicro_001190 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)/C=C/c2ccccc2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L13 compound treatment 699924.0 458000.0 0.95 666838.0 435000.0 0.94 1.3347 1.0 1642178 CBMicro_001191 CCOc1ccc(Nc2nc(cs2)c3sc(NC(=O)CC)nc3C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L14 compound treatment 937596.0 696000.0 1.44 872299.0 640000.0 1.39 1.9961 0.9998 1233766 CBMicro_001192 Cc1ccc(C)n1c2ccc(cc2C)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L15 compound treatment 718056.0 477000.0 0.98 681228.0 449000.0 0.97 1.3832 1.0 1923889 CBMicro_001193 COc1ccc(/C=C/C(=O)Nc2ccc(F)cc2)cc1Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L16 compound treatment 692952.0 451000.0 0.93 678264.0 446000.0 0.97 1.342 0.9998 1923890 CBMicro_001194 Cc1cccc(NC(=O)C(=O)NCc2ccco2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L17 compound treatment 729090.0 488000.0 1.01 694009.0 462000.0 1.0 1.4188 1.0 1273549 CBMicro_001195 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L18 compound treatment 699446.0 458000.0 0.95 684678.0 453000.0 0.98 1.3613 0.9998 1923891 CBMicro_001196 FC(F)(F)c1cccc(NC(=O)C(=O)NCc2ccco2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L19 compound treatment 731661.0 490000.0 1.01 758981.0 527000.0 1.14 1.522 0.9982 1403671 CBMicro_001197 CS(=O)(=O)N1CCN(CC1)C(=O)COc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L20 compound treatment 726631.0 485000.0 1.0 715560.0 484000.0 1.05 1.4482 0.9998 1923892 CBMicro_001198 Fc1ccccc1COc2ccc(/C=C/3\C(=O)NN(C3=O)c4ccccc4)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L21 compound treatment 723813.0 482000.0 1.0 705644.0 474000.0 1.03 1.4289 0.9999 1923893 CBMicro_001199 CCOC(=O)c1c(N)scc1c2ccc(cc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L22 compound treatment 744336.0 503000.0 1.04 687639.0 456000.0 0.99 1.4313 0.9997 1385046 CBMicro_001200 COc1ccc(Cl)cc1NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L23 mock treatment 715400.0 474000.0 0.98 684174.0 452000.0 0.98 1.3838 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 L24 mock treatment 234555.0 -6940.0 -0.01 232450.0 467.0 0.0 -0.0094 -0.6556 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M01 mock treatment 15204.0 -226000.0 -0.47 14607.0 -217000.0 -0.47 -0.663 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M02 mock treatment 14314.0 -227000.0 -0.47 12461.0 -220000.0 -0.48 -0.6676 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M03 compound treatment 701240.0 460000.0 0.95 664094.0 432000.0 0.94 1.3324 1.0 1923894 CBMicro_001201 CCOC(=O)C(=O)Nc1ccc(cc1)C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M04 compound treatment 659402.0 418000.0 0.86 636828.0 405000.0 0.88 1.2296 1.0 1923895 CBMicro_001202 Cc1cccc(NC(=O)C2CC(=O)N=C(N)S2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M05 compound treatment 678903.0 437000.0 0.9 669837.0 438000.0 0.95 1.3086 0.9997 1923896 CBMicro_001203 CC(C)CCNC(=O)c1ccc(Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M06 compound treatment 676202.0 435000.0 0.9 647775.0 416000.0 0.9 1.2709 1.0 1923897 CBMicro_001204 CCOc1ccc(NC(=S)NC(NC(=O)c2cccc(I)c2)C(Cl)(Cl)Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M07 compound treatment 717394.0 476000.0 0.98 723830.0 492000.0 1.06 1.4474 0.9992 1320675 CBMicro_001205 Brc1ccc(N=c2sc(NC(=O)c3ccco3)c(c4ccccc4)n2CC=C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M08 compound treatment 694758.0 453000.0 0.94 645116.0 413000.0 0.89 1.2939 0.9997 1923898 CBMicro_001206 COc1ccc(Cl)cc1N2C(=O)C3C(OC4(C3C2=O)C(=O)c5ccccc5C4=O)c6ccc(Cl)cc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M09 compound treatment 704249.0 463000.0 0.96 683046.0 451000.0 0.98 1.3658 0.9999 1923899 CBMicro_001207 Cc1ccc(cc1C)N2CC(=O)NN=C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M10 compound treatment 718628.0 477000.0 0.98 637910.0 406000.0 0.88 1.3177 0.9984 1923900 CBMicro_001208 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc([N+](=O)[O-])c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M11 compound treatment 756406.0 515000.0 1.06 672662.0 441000.0 0.95 1.426 0.9985 1923901 CBMicro_001209 Cc1cccc(NC2=NC(=O)/C(=C\c3ccc(cc3)[N+](=O)[O-])/S2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M12 compound treatment 690330.0 449000.0 0.93 646400.0 414000.0 0.9 1.2894 0.9999 1923902 CBMicro_001210 CC1=C/C(=N\N=C\2/SC(CC(=O)Nc3ccc(cc3)C(=O)O)C(=N2)O)/CC(C)(C)C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M13 compound treatment 722578.0 481000.0 0.99 686549.0 455000.0 0.98 1.3979 1.0 1357975 CBMicro_001211 CC(Oc1ccccc1)C(=O)Nc2ccc(I)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M14 compound treatment 710423.0 469000.0 0.97 654794.0 423000.0 0.92 1.3316 0.9996 1923903 CBMicro_001212 CCN1CN=C2SC(CO)(CO)C(=O)N2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M15 compound treatment 686373.0 445000.0 0.92 663966.0 432000.0 0.93 1.3105 1.0 1923904 CBMicro_001213 OC(CC#CCN1CCC(C1)c2ccccc2)(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M16 compound treatment 663099.0 422000.0 0.87 629492.0 398000.0 0.86 1.2238 1.0 1547419 CBMicro_001214 C(Nc1cccc(c1)c2nc3ccccc3s2)c4cccnc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M17 compound treatment 723520.0 482000.0 1.0 696488.0 465000.0 1.01 1.4145 1.0 1923905 CBMicro_001215 COc1ccc(Cl)cc1NC(=O)C2=C(C)NC(=S)NC2c3ccccc3Br 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M18 compound treatment 727782.0 486000.0 1.0 684154.0 452000.0 0.98 1.4018 0.9999 1706233 CBMicro_001216 CCC(C(=O)Nc1ccccc1CC)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M19 compound treatment 710774.0 469000.0 0.97 672610.0 441000.0 0.95 1.3594 1.0 1681329 CBMicro_001217 Cn1c2NC3=C(C(c4ccc(OCc5ccccc5)cc4)c2c(=O)[nH]c1=O)C(=O)c6ccccc36 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M20 compound treatment 753129.0 512000.0 1.06 676757.0 445000.0 0.96 1.4275 0.9989 1687704 CBMicro_001218 COc1cc(C)nc(Nc2nc(C)c3ccc(C)cc3n2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M21 compound treatment 727310.0 486000.0 1.0 708900.0 477000.0 1.03 1.439 0.9999 1923906 CBMicro_001219 Clc1cc(Cl)c(NC(=O)CCc2ccccc2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M22 compound treatment 711383.0 470000.0 0.97 674241.0 442000.0 0.96 1.3627 1.0 1398916 CBMicro_001220 CCOC(=O)c1cnc2cc(nn2c1O)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M23 mock treatment 716542.0 475000.0 0.98 670428.0 438000.0 0.95 1.3644 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 M24 mock treatment 393242.0 152000.0 0.31 372634.0 141000.0 0.3 0.4368 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N01 mock treatment 14670.0 -227000.0 -0.47 14325.0 -218000.0 -0.47 -0.6642 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N02 mock treatment 13738.0 -228000.0 -0.47 12911.0 -219000.0 -0.47 -0.6677 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N03 compound treatment 641822.0 400000.0 0.83 630603.0 399000.0 0.86 1.1944 0.9998 1923907 CBMicro_001221 O=C/1OC(=N\C1=C/c2ccccc2)C3(CC4CC5CC(C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N04 compound treatment 654155.0 413000.0 0.85 622669.0 391000.0 0.85 1.2003 1.0 1377941 CBMicro_001222 O=C(N1CCN(CC1)C(=O)c2ccc(cc2)c3ccccc3)c4cccs4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N05 compound treatment 671731.0 430000.0 0.89 654736.0 423000.0 0.92 1.275 0.9999 1343819 CBMicro_001223 CCOc1ccc2nc(NC(=O)c3cccc(Br)c3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N06 compound treatment 669424.0 428000.0 0.88 632234.0 400000.0 0.87 1.2372 1.0 1923908 CBMicro_001224 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cccc(OCCOc4ccccc4)c3)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N07 compound treatment 665477.0 424000.0 0.88 667119.0 435000.0 0.94 1.2848 0.9993 1923909 CBMicro_001225 COc1ccc2occ(C(=O)c3ccc(cc3)[N+](=O)[O-])c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N08 compound treatment 700472.0 459000.0 0.95 628123.0 396000.0 0.86 1.2762 0.9988 1140474 CBMicro_001226 COc1ccc(NC(=O)CN(CCc2ccccc2)S(=O)(=O)c3ccccc3)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N09 compound treatment 680564.0 439000.0 0.91 646357.0 414000.0 0.9 1.2751 1.0 1923910 CBMicro_001227 Clc1ccccc1CSc2nnnn2c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N10 compound treatment 664940.0 423000.0 0.87 636437.0 404000.0 0.88 1.2371 1.0 1134483 CBMicro_001228 COc1ccccc1C(=O)N2CCN(CC2)C(=O)COc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N11 compound treatment 696297.0 455000.0 0.94 667059.0 435000.0 0.94 1.3297 1.0 1398039 CBMicro_001229 OC(=O)c1ccc(Nc2nc(cs2)c3ccc(Br)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N12 compound treatment 648737.0 407000.0 0.84 626623.0 395000.0 0.85 1.1984 1.0 1187775 CBMicro_001230 Cc1ccc(C)n1c2cc(ccc2O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N13 compound treatment 688316.0 447000.0 0.92 635545.0 404000.0 0.87 1.2698 0.9996 1923911 CBMicro_001231 CC(=O)Nc1ccc(Nc2nc(cs2)c3ccc(Br)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N14 compound treatment 672802.0 431000.0 0.89 634717.0 403000.0 0.87 1.2459 0.9999 1923912 CBMicro_001232 Cc1ccc(cc1)S(=O)(=O)N2CCN(Cc3ccccc3[N+](=O)[O-])CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N15 compound treatment 701873.0 460000.0 0.95 667220.0 435000.0 0.94 1.3381 1.0 1923913 CBMicro_001233 [O-][N+](=C1C=CC2(N(Cc3ccccc3)C4=CC=CC=CC4=[N+]2Cc5ccccc5)C(=C1)[N+](=O)[O-])[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N16 compound treatment 700848.0 459000.0 0.95 629936.0 398000.0 0.86 1.2796 0.9988 1923914 CBMicro_001234 [O-][N+](=O)c1cccc(/C=N/N2C(=O)c3cccc4cccc(C2=O)c34)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N17 compound treatment 722903.0 481000.0 0.99 719920.0 488000.0 1.06 1.4495 0.9995 1923915 CBMicro_001235 Cc1cc2NC(C)(C)c3ssc(=S)c3-c2cc1[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N18 compound treatment 680517.0 439000.0 0.91 681627.0 450000.0 0.97 1.329 0.9994 1923916 CBMicro_001236 CCc1ccc(NC(=O)C(=O)NCc2ccc3OCOc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N19 compound treatment 717022.0 476000.0 0.98 684655.0 453000.0 0.98 1.3869 1.0 1627136 CBMicro_001237 O=C(NCCc1c[nH]c2ccccc12)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N20 compound treatment 715789.0 474000.0 0.98 671179.0 439000.0 0.95 1.3645 0.9999 1923917 CBMicro_001238 CCOC(=O)C1=C(N=C2SCC(=O)N2C1c3ccc(OC)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N21 compound treatment 698499.0 457000.0 0.94 675671.0 444000.0 0.96 1.3461 1.0 1386495 CBMicro_001239 CCc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N22 compound treatment 672709.0 431000.0 0.89 665950.0 434000.0 0.94 1.2936 0.9996 1923918 CBMicro_001240 CCOC(=O)C1=C(Nc2cccc3ccccc23)S/C(=C\c4ccccc4)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N23 mock treatment 715177.0 474000.0 0.98 671384.0 439000.0 0.95 1.3639 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 N24 mock treatment 234513.0 -6990.0 -0.01 161829.0 -70200.0 -0.15 -0.1176 -0.7708 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O01 mock treatment 14503.0 -227000.0 -0.47 14555.0 -217000.0 -0.47 -0.6641 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O02 mock treatment 14126.0 -227000.0 -0.47 14398.0 -218000.0 -0.47 -0.6649 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O03 compound treatment 645245.0 404000.0 0.83 621602.0 390000.0 0.84 1.1856 1.0 1315068 CBMicro_001241 Ic1ccc(cc1)S(=O)(=O)N2CCCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O04 compound treatment 672887.0 431000.0 0.89 625210.0 393000.0 0.85 1.2315 0.9997 1923919 CBMicro_001242 O=C(CCN1C(=O)/C(=C/c2cccs2)/SC1=S)NC3(CC4CC5CC(C4)C3)C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O05 compound treatment 660747.0 419000.0 0.87 637686.0 406000.0 0.88 1.2329 1.0 1287245 CBMicro_001243 CCSc1nnc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O06 compound treatment 629940.0 388000.0 0.8 597713.0 366000.0 0.79 1.1267 1.0 1923920 CBMicro_001244 CC(=O)Nc1nc(cs1)c2cc(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O07 compound treatment 719185.0 478000.0 0.99 644767.0 413000.0 0.89 1.329 0.9988 1923921 CBMicro_001245 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O08 compound treatment 644982.0 403000.0 0.83 612004.0 380000.0 0.82 1.1706 1.0 1783022 CBMicro_001246 COc1cc(C(=O)N2CCCc3ccccc23)c(cc1OC)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O09 compound treatment 679405.0 438000.0 0.9 643378.0 411000.0 0.89 1.2688 1.0 1712468 CBMicro_001247 O=C(CN(Cc1ccccc1)S(=O)(=O)c2ccccc2)NCc3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O10 compound treatment 656741.0 415000.0 0.86 629660.0 398000.0 0.86 1.2147 1.0 1923922 CBMicro_001248 CCOc1ccc(NC(=S)NC(NC(=O)c2cc(OC)c(OC)c(OC)c2)C(Cl)(Cl)Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O11 compound treatment 675081.0 434000.0 0.9 639220.0 407000.0 0.88 1.2562 1.0 1923923 CBMicro_001249 CCN1C(=C)c2ccc(C)cc2NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O12 compound treatment 663801.0 422000.0 0.87 597077.0 365000.0 0.79 1.1752 0.9988 1923924 CBMicro_001250 FC(F)(F)c1cccc(c1)C(=O)Nc2ccc(cc2)c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O13 compound treatment 685369.0 444000.0 0.92 635783.0 404000.0 0.87 1.2659 0.9997 1923925 CBMicro_001251 CCOC(=O)Nc1sc2CC(CC)CCc2c1C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O14 compound treatment 665536.0 424000.0 0.88 611926.0 380000.0 0.82 1.2004 0.9995 1320945 CBMicro_001252 Cc1cccc(OCC(=O)Nc2ccc3OCOc3c2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O15 compound treatment 697318.0 456000.0 0.94 639736.0 408000.0 0.88 1.2894 0.9995 1666569 CBMicro_001253 Cc1ccnc(SC2CC(=O)N(C2=O)c3ccccc3)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O16 compound treatment 691681.0 450000.0 0.93 625477.0 393000.0 0.85 1.2593 0.9991 1923926 CBMicro_001254 Cc1cc(C)n(n1)C(=O)CNC(=O)c2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O17 compound treatment 703423.0 462000.0 0.95 668024.0 436000.0 0.94 1.3416 1.0 1923927 CBMicro_001255 [O-][N+](=O)c1ccc(cc1)c2ccc(o2)C(=O)NCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O18 compound treatment 687674.0 446000.0 0.92 629923.0 398000.0 0.86 1.2603 0.9994 1709888 CBMicro_001256 COc1ccc(Cl)cc1C(=O)N(Cc2ccccc2)C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O19 compound treatment 696770.0 455000.0 0.94 669976.0 438000.0 0.95 1.3349 1.0 1269622 CBMicro_001257 COc1ccc(Cl)cc1C(=O)Nc2ccccc2I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O20 compound treatment 711099.0 470000.0 0.97 641509.0 410000.0 0.89 1.3122 0.999 1923928 CBMicro_001258 Cc1cc(C)n(n1)C(=O)CNC(=O)c2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O21 compound treatment 710095.0 469000.0 0.97 677012.0 445000.0 0.96 1.3651 1.0 1923929 CBMicro_001259 COc1cccc(C2NC(=S)NC(=C2C(=O)Nc3ccc(Br)cc3)C)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O22 compound treatment 680425.0 439000.0 0.91 623783.0 392000.0 0.85 1.2403 0.9995 1561943 CBMicro_001260 Cc1cccc(OCC(=O)Nc2cccc(c2)C(=O)O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O23 mock treatment 698667.0 457000.0 0.94 654443.0 422000.0 0.91 1.3139 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 O24 mock treatment 210878.0 -30600.0 -0.06 401578.0 170000.0 0.37 0.2149 0.5769 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P01 mock treatment 14838.0 -227000.0 -0.47 14052.0 -218000.0 -0.47 -0.6644 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P02 mock treatment 15100.0 -226000.0 -0.47 15026.0 -217000.0 -0.47 -0.6625 -1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P03 compound treatment 604952.0 363000.0 0.75 561070.0 329000.0 0.71 1.0342 0.9997 1485288 CBMicro_001261 Cc1cc2ncn(CC(=O)N3CCOCC3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P04 compound treatment 602945.0 361000.0 0.75 561292.0 329000.0 0.71 1.0316 0.9997 1076350 CBMicro_001262 O=c1oc(nc2ccccc12)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P05 compound treatment 610223.0 369000.0 0.76 556565.0 325000.0 0.7 1.035 0.9992 1524092 CBMicro_001263 O=C(Nc1nc(c(s1)c2ccccc2)c3ccccc3)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P06 compound treatment 623908.0 382000.0 0.79 567163.0 335000.0 0.73 1.0712 0.9991 1382931 CBMicro_001264 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3cc(OC)ccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P07 compound treatment 665120.0 424000.0 0.87 562443.0 330000.0 0.72 1.1241 0.995 1431832 CBMicro_001265 Cn1c2ccccc2c3nnc(SCC(=O)N(c4ccccc4)c5ccccc5)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P08 compound treatment 782483.0 541000.0 1.12 706751.0 475000.0 1.03 1.5163 0.9991 1548212 CBMicro_001266 CCOC(=O)C1=C(N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4ccc(OC)cc4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P09 compound treatment 624179.0 383000.0 0.79 564413.0 332000.0 0.72 1.0674 0.9989 1923930 CBMicro_001267 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)c4ccc(cc4Cl)[N+](=O)[O-])/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P10 compound treatment 645133.0 404000.0 0.83 588725.0 357000.0 0.77 1.1352 0.9993 1176579 CBMicro_001268 Clc1ccc2c(=O)oc(nc2c1)c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P11 compound treatment 625583.0 384000.0 0.79 565909.0 334000.0 0.72 1.0717 0.9989 1137616 CBMicro_001269 Cn1c(SCC(=O)Nc2ccc(F)cc2)nc3n(C)c(=O)n(C)c(=O)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P12 compound treatment 665913.0 424000.0 0.88 603156.0 371000.0 0.8 1.1876 0.9991 1124337 CBMicro_001270 COc1cc(C(=O)O)c(cc1OC)n2c(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P13 compound treatment 641536.0 400000.0 0.83 559768.0 328000.0 0.71 1.0856 0.9971 1923931 CBMicro_001271 CO/N=C(\N1CCN(CC1)c2ccc(cc2)[N+](=O)[O-])/c3nonc3N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P14 compound treatment 594715.0 353000.0 0.73 546573.0 315000.0 0.68 0.997 0.9994 1360703 CBMicro_001272 Cc1ccc(C)n1c2ccc(O)cc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P15 compound treatment 655140.0 414000.0 0.85 576253.0 344000.0 0.75 1.1307 0.9977 1787296 CBMicro_001273 COc1ccccc1C(=O)N2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P16 compound treatment 659114.0 418000.0 0.86 576373.0 344000.0 0.75 1.1367 0.9974 1923932 CBMicro_001274 Fc1ccccc1OCCNC(=O)c2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P17 compound treatment 661767.0 420000.0 0.87 583606.0 352000.0 0.76 1.1516 0.9979 1283992 CBMicro_001275 Cc1ccc(OCC(=O)Nc2ccc(C)c(C)c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P18 compound treatment 673164.0 432000.0 0.89 595651.0 364000.0 0.79 1.1867 0.9981 1923933 CBMicro_001276 CCc1ccc(NC(=O)C(=O)NCCCN2CCOCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P19 compound treatment 653530.0 412000.0 0.85 590505.0 359000.0 0.78 1.1501 0.999 1639449 CBMicro_001277 CCOc1ccccc1NC(=O)CCN2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P20 compound treatment 648057.0 407000.0 0.84 592954.0 361000.0 0.78 1.1459 0.9994 1923934 CBMicro_001278 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OCCOc4ccc(C)cc4)c(OC)c3)/C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P21 compound treatment 671833.0 430000.0 0.89 589232.0 357000.0 0.77 1.1749 0.9976 1923935 CBMicro_001279 Cc1cc(O)nc(SCc2ccc(Cl)cc2Cl)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P22 compound treatment 649444.0 408000.0 0.84 581391.0 349000.0 0.76 1.1302 0.9986 1660969 CBMicro_001280 CC1CC(C)(C)N(C(=O)Nc2ccccc2)c3cc(C)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P23 mock treatment 643147.0 402000.0 0.83 587808.0 356000.0 0.77 1.1309 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.689 P24 mock treatment 325752.0 84300.0 0.17 220878.0 -11100.0 -0.02 0.106 0.6037 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A01 mock treatment 17403.0 -225000.0 -0.46 15812.0 -221000.0 -0.48 -0.6656 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A02 mock treatment 17728.0 -224000.0 -0.46 17068.0 -219000.0 -0.47 -0.6632 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A03 compound treatment 597784.0 356000.0 0.73 557456.0 321000.0 0.7 1.0105 0.9996 1923936 CBMicro_001281 Fc1ccc(cc1)c2ccc(/C=C/3\C(=O)NN(C3=O)c4ccccc4)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A04 compound treatment 589192.0 347000.0 0.72 564958.0 329000.0 0.71 1.0094 1.0 1379566 CBMicro_001282 Cc1cccc(C)c1NC(=O)CSc2nc3ccccc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A05 compound treatment 595504.0 353000.0 0.73 568228.0 332000.0 0.72 1.0236 1.0 1923937 CBMicro_001283 O/N=C(/CC1(O)C(=O)Nc2ccccc21)\c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A06 compound treatment 632131.0 390000.0 0.8 575425.0 339000.0 0.73 1.0881 0.9989 1923938 CBMicro_001284 Cc1cccc(C)c1NC(=O)CSCC(=O)Nc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A07 compound treatment 615124.0 373000.0 0.77 580422.0 344000.0 0.74 1.0709 0.9999 1162093 CBMicro_001285 CCOC(=O)c1cnc2cc(nn2c1O)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A08 compound treatment 652033.0 410000.0 0.85 585475.0 349000.0 0.76 1.1326 0.9984 1923939 CBMicro_001286 OC(=O)c1ccc(NC(=O)CC2S/C(=N\N=C\c3ccccc3)/N=C2O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A09 compound treatment 652527.0 410000.0 0.85 620496.0 384000.0 0.83 1.1869 1.0 1923940 CBMicro_001287 [O-][N+](=O)c1ccc2nc(NC(=O)c3cccc(Oc4ccccc4)c3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A10 compound treatment 646071.0 404000.0 0.83 582036.0 346000.0 0.75 1.1186 0.9985 1923941 CBMicro_001288 COc1cccc(OCCNC(=O)c2cc(OC)c(OC)c(OC)c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A11 compound treatment 625040.0 383000.0 0.79 576480.0 340000.0 0.74 1.0794 0.9994 1923942 CBMicro_001289 CN1C2=CC=CC=CC2=[N+](C)C31C=CC(=[N+]([O-])[O-])C=C3[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A12 compound treatment 629501.0 387000.0 0.8 599406.0 363000.0 0.79 1.121 1.0 1923943 CBMicro_001290 Cn1c(SCc2ccc(cc2)[N+](=O)[O-])nc3n(C)c(=O)n(C)c(=O)c13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A13 compound treatment 644900.0 403000.0 0.83 610300.0 374000.0 0.81 1.1601 0.9999 1923944 CBMicro_001291 CC(C)c1ccc(CNC(=O)CSCC(=O)Nc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A14 compound treatment 684232.0 442000.0 0.91 621602.0 385000.0 0.83 1.2348 0.999 1495182 CBMicro_001292 COc1ccc(cc1OC)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A15 compound treatment 763563.0 521000.0 1.08 719808.0 483000.0 1.05 1.5009 0.9999 1323734 CBMicro_001293 Cc1ccc(C)n1c2ccc(Br)cc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A16 compound treatment 710392.0 468000.0 0.97 635553.0 399000.0 0.86 1.2944 0.9984 1923945 CBMicro_001294 Fc1ccccc1COc2ccccc2/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A17 compound treatment 647979.0 406000.0 0.84 588241.0 352000.0 0.76 1.1309 0.9989 1923946 CBMicro_001295 Oc1cc(O)nc(SCc2ccc(Cl)cc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A18 compound treatment 651663.0 409000.0 0.85 604217.0 368000.0 0.8 1.1607 0.9996 1923947 CBMicro_001296 CN1C(=O)N(C)C(=O)C(=Cc2ccc(O)c(c2)[N+](=O)[O-])C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A19 compound treatment 648803.0 407000.0 0.84 606302.0 370000.0 0.8 1.1597 0.9997 1923948 CBMicro_001297 Cc1cc(C(=O)Nc2cccc3ccccc23)c(C)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A20 compound treatment 622432.0 380000.0 0.78 589693.0 353000.0 0.76 1.0958 0.9999 1923949 CBMicro_001298 Fc1ccccc1COc2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A21 compound treatment 637450.0 395000.0 0.82 592313.0 356000.0 0.77 1.1217 0.9996 1215989 CBMicro_001299 COc1ccc(N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A22 compound treatment 624054.0 382000.0 0.79 566900.0 331000.0 0.72 1.0633 0.9988 1497881 CBMicro_001300 COc1cc(ccc1O)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A23 mock treatment 616169.0 374000.0 0.77 560789.0 324000.0 0.7 1.0424 0.9989 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 A24 mock treatment 196563.0 -45700.0 -0.09 222711.0 -13600.0 -0.03 -0.0875 -0.8858 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B01 mock treatment 17372.0 -225000.0 -0.46 15833.0 -220000.0 -0.48 -0.6657 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B02 mock treatment 17644.0 -225000.0 -0.46 17037.0 -219000.0 -0.47 -0.6634 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B03 compound treatment 666985.0 425000.0 0.88 646227.0 410000.0 0.89 1.2474 1.0 1635923 CBMicro_001301 COc1ccc(Cc2noc(n2)c3ccc(OC)c(OC)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B04 compound treatment 650491.0 408000.0 0.84 619818.0 384000.0 0.83 1.1829 1.0 1722025 CBMicro_001302 COc1ccccc1C=c2sc3nc4c(Br)c(C)c(C)cc4n3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B05 compound treatment 684455.0 442000.0 0.91 652046.0 416000.0 0.9 1.2818 1.0 1923950 CBMicro_001303 [O-][N+](=O)c1cccc(c1)c2noc(CCc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B06 compound treatment 651311.0 409000.0 0.84 636752.0 400000.0 0.87 1.21 0.9999 1310332 CBMicro_001304 Cn1c(=O)n(C)c2nc(S)n(Cc3ccccc3Cl)c2c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B07 compound treatment 702026.0 460000.0 0.95 677378.0 441000.0 0.95 1.3462 1.0 1923951 CBMicro_001305 OC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)NN(C3=O)c4ccccc4)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B08 compound treatment 662235.0 420000.0 0.87 665669.0 429000.0 0.93 1.2702 0.9994 1225450 CBMicro_001306 Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B09 compound treatment 705037.0 463000.0 0.96 699989.0 464000.0 1.0 1.3852 0.9997 1923952 CBMicro_001307 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B10 compound treatment 742331.0 500000.0 1.03 665784.0 429000.0 0.93 1.3873 0.9986 1923953 CBMicro_001308 [O-][N+](=O)c1ccc(cc1)C2NC(=O)NC(=C2c3ccc4ccccc4n3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B11 compound treatment 711398.0 469000.0 0.97 661263.0 425000.0 0.92 1.3352 0.9997 1216181 CBMicro_001309 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B12 compound treatment 704157.0 462000.0 0.95 683572.0 447000.0 0.97 1.3588 1.0 1923954 CBMicro_001310 Cc1ccc2ncnc(NCCCN3CCOCC3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B13 compound treatment 727096.0 485000.0 1.0 707305.0 471000.0 1.02 1.4286 1.0 1624684 CBMicro_001311 Fc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc5OCOc5c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B14 compound treatment 710753.0 469000.0 0.97 670512.0 434000.0 0.94 1.3484 0.9999 1683356 CBMicro_001312 CCN(CC)CCN1C(Nc2ccccc2C1=O)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B15 compound treatment 722605.0 480000.0 0.99 720678.0 484000.0 1.05 1.4425 0.9996 1659738 CBMicro_001313 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCc2ccco2)Cc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B16 compound treatment 710162.0 468000.0 0.97 675472.0 439000.0 0.95 1.3551 1.0 1559257 CBMicro_001314 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(C)c3)cc2)ncn1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B17 compound treatment 715968.0 474000.0 0.98 680201.0 444000.0 0.96 1.3709 1.0 1424218 CBMicro_001315 CCCc1cc(O)n2nc(cc2n1)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B18 compound treatment 700538.0 458000.0 0.95 656419.0 420000.0 0.91 1.3119 0.9998 1923955 CBMicro_001316 Cc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B19 compound treatment 738418.0 496000.0 1.02 686905.0 451000.0 0.98 1.4139 0.9997 1923956 CBMicro_001317 Cc1ccsc1/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B20 compound treatment 680095.0 438000.0 0.9 638898.0 403000.0 0.87 1.2553 0.9998 1923957 CBMicro_001318 CC(=O)c1cccc(Nc2ncnc3ccc(C)cc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B21 compound treatment 698029.0 456000.0 0.94 686519.0 450000.0 0.97 1.3543 0.9998 1923958 CBMicro_001319 Cc1cc(C=O)c(C)n1c2ccc(C)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B22 compound treatment 648406.0 406000.0 0.84 632222.0 396000.0 0.86 1.1988 0.9999 1570528 CBMicro_001320 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B23 mock treatment 664871.0 423000.0 0.87 654883.0 419000.0 0.91 1.2575 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 B24 mock treatment 217318.0 -24900.0 -0.05 231434.0 -4880.0 -0.01 -0.0438 -0.835 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C01 mock treatment 17121.0 -225000.0 -0.46 15225.0 -221000.0 -0.48 -0.667 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C02 mock treatment 17152.0 -225000.0 -0.46 15843.0 -220000.0 -0.48 -0.666 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C03 compound treatment 665551.0 423000.0 0.87 655875.0 420000.0 0.91 1.26 0.9998 1923959 CBMicro_001321 COc1ccc2nc(N/C(=N/C(=O)Cc3ccc(Cl)cc3)/N)nc(C)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C04 compound treatment 650017.0 408000.0 0.84 642727.0 406000.0 0.88 1.2172 0.9998 1595124 CBMicro_001322 O=C1NC(=O)c2ccc3CCc4ccc1c2c43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C05 compound treatment 685822.0 444000.0 0.92 666093.0 430000.0 0.93 1.3053 1.0 1923960 CBMicro_001323 COc1ccccc1/C=N/N=C/2\SC(CC(=O)Nc3cccc(C)c3C)C(=N2)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C06 compound treatment 697833.0 456000.0 0.94 635921.0 400000.0 0.86 1.2766 0.9991 1923961 CBMicro_001324 COc1cc(cc(OC)c1OC)C(=O)NCCOc2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C07 compound treatment 696483.0 454000.0 0.94 650298.0 414000.0 0.9 1.2966 0.9997 1567230 CBMicro_001325 CCCOC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C08 compound treatment 685934.0 444000.0 0.92 662444.0 426000.0 0.92 1.2998 1.0 1172702 CBMicro_001326 O=C(Nc1ccc(OCc2ccccc2)cc1)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C09 compound treatment 716266.0 474000.0 0.98 701867.0 466000.0 1.01 1.4045 0.9999 1923962 CBMicro_001327 CCn1c2ccccc2c3nnc(SC)nc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C10 compound treatment 712379.0 470000.0 0.97 657251.0 421000.0 0.91 1.3305 0.9995 1923963 CBMicro_001328 COc1cccc(OCCNC(=O)Cc2cccc3ccccc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C11 compound treatment 754850.0 513000.0 1.06 668038.0 432000.0 0.93 1.409 0.9981 1787291 CBMicro_001329 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C12 compound treatment 729476.0 487000.0 1.01 680958.0 445000.0 0.96 1.3917 0.9998 1282085 CBMicro_001330 Cn1c(nc2n(C)c(=O)n(C)c(=O)c12)n3ccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C13 compound treatment 748770.0 507000.0 1.05 707274.0 471000.0 1.02 1.4602 0.9999 1923964 CBMicro_001331 Fc1ccc(NC(=O)C(=O)NCCCN2CCOCC2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C14 compound treatment 733345.0 491000.0 1.01 709489.0 473000.0 1.02 1.441 1.0 1923965 CBMicro_001332 COc1ccccc1NC(=O)C2=C(C)NC(=S)NC2c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C15 compound treatment 749433.0 507000.0 1.05 720840.0 485000.0 1.05 1.4819 1.0 1629952 CBMicro_001333 CCc1ccc(CN2CCN(CC2)C(=O)CC(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C16 compound treatment 758480.0 516000.0 1.07 742829.0 507000.0 1.1 1.5288 0.9999 1452170 CBMicro_001334 Cc1ccc(C)n1c2ccc(OCC(=O)O)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C17 compound treatment 729774.0 488000.0 1.01 676547.0 440000.0 0.95 1.3854 0.9996 1923966 CBMicro_001335 CCCCOc1ccc(cc1)C(=O)Nc2ccccc2OC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C18 compound treatment 735637.0 493000.0 1.02 672446.0 436000.0 0.94 1.3877 0.9993 1923967 CBMicro_001336 CC1(C)CC(CC(C)(C)N1)NC(=S)Nc2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C19 compound treatment 680738.0 439000.0 0.91 681598.0 445000.0 0.96 1.3216 0.9995 1923968 CBMicro_001337 CCCCOc1ccc(cc1)C(=O)NCCOc2ccc(C)c(C)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C20 compound treatment 765776.0 524000.0 1.08 669308.0 433000.0 0.94 1.4269 0.9975 1923969 CBMicro_001338 OC(=O)CCC(=O)N1N=C(CC1c2ccc(cc2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C21 compound treatment 712022.0 470000.0 0.97 680522.0 444000.0 0.96 1.3656 1.0 1923970 CBMicro_001339 O=C(NCCCN1CCOCC1)C(=O)NCc2ccco2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C22 compound treatment 676932.0 435000.0 0.9 632305.0 396000.0 0.86 1.2406 0.9997 1923971 CBMicro_001340 Cc1nc2cc(nn2c(C)c1Cl)c3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C23 mock treatment 698110.0 456000.0 0.94 646382.0 410000.0 0.89 1.293 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 C24 mock treatment 218575.0 -23700.0 -0.05 210501.0 -25800.0 -0.06 -0.074 -0.9977 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D01 mock treatment 15759.0 -226000.0 -0.47 14838.0 -221000.0 -0.48 -0.6695 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D02 mock treatment 16775.0 -225000.0 -0.47 14419.0 -222000.0 -0.48 -0.6687 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D03 compound treatment 656755.0 415000.0 0.86 658318.0 422000.0 0.91 1.2509 0.9995 1923972 CBMicro_001341 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2C(F)(F)F)C(=N1)O)/c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D04 compound treatment 652620.0 410000.0 0.85 657695.0 421000.0 0.91 1.2439 0.9993 1923973 CBMicro_001342 COc1cccc(/C=C\2/C(=O)NN(C2=O)c3ccc(Br)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D05 compound treatment 685267.0 443000.0 0.91 680612.0 444000.0 0.96 1.3267 0.9997 1542233 CBMicro_001343 Cc1ccc(cc1C)c2n[nH]c(=S)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D06 compound treatment 666921.0 425000.0 0.88 648463.0 412000.0 0.89 1.2507 1.0 1716452 CBMicro_001344 Cc1ccc(Cn2c(=O)n(C)c3ncn(C)c3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D07 compound treatment 673483.0 431000.0 0.89 673761.0 437000.0 0.95 1.299 0.9995 1290732 CBMicro_001345 OC(=O)c1cc(NC(=O)c2ccco2)cc(c1)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D08 compound treatment 670494.0 428000.0 0.88 681425.0 445000.0 0.96 1.3064 0.9991 1923974 CBMicro_001346 CCc1cc(=O)oc2cc(OCC(=O)C)ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D09 compound treatment 707056.0 465000.0 0.96 710575.0 474000.0 1.03 1.4043 0.9994 1281963 CBMicro_001347 Clc1ccccc1CSc2nc3cccnc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D10 compound treatment 720792.0 479000.0 0.99 707740.0 471000.0 1.02 1.42 0.9999 1923975 CBMicro_001348 CC(=O)Oc1ccc2c(C)c(C)c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D11 compound treatment 709463.0 467000.0 0.96 776296.0 540000.0 1.17 1.5084 0.9954 1289374 CBMicro_001349 O=C(CC1Sc2ccccc2NC1=O)Nc3ccccc3NC(=O)CC4Sc5ccccc5NC4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D12 compound treatment 708880.0 467000.0 0.96 694169.0 458000.0 0.99 1.3819 0.9999 1923976 CBMicro_001350 Cc1ccc(N2C(=O)C(=C(Nc3ccc(C)c(C)c3)C2=O)Cl)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D13 compound treatment 730072.0 488000.0 1.01 735525.0 499000.0 1.08 1.4761 0.9994 1923977 CBMicro_001351 OC1=N/C(=N/N=C/2\CCCc3ccccc23)/SC1CC(=O)Nc4ccccc4C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D14 compound treatment 716952.0 475000.0 0.98 667179.0 431000.0 0.93 1.3524 0.9997 1923978 CBMicro_001352 COc1ccc(cc1)c2cc(O)n3nc(cc3n2)c4cccc(C)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D15 compound treatment 716926.0 475000.0 0.98 726746.0 490000.0 1.06 1.4435 0.9992 1923979 CBMicro_001353 COc1ccc(NC(=S)NCc2ccc(Cl)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D16 compound treatment 719572.0 477000.0 0.99 712432.0 476000.0 1.03 1.4254 0.9997 1730196 CBMicro_001354 COc1cc2ccccc2cc1C(=O)Nc3ccc4C(=O)N(C)C(=O)c4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D17 compound treatment 755115.0 513000.0 1.06 731572.0 495000.0 1.07 1.5066 1.0 1151088 CBMicro_001355 Cn1cnc2n(C)c(=O)n(Cc3ccc(F)cc3)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D18 compound treatment 696800.0 455000.0 0.94 691860.0 456000.0 0.99 1.3607 0.9997 1785997 CBMicro_001356 CC1=C(C)CC2C(C1)C(=O)N(C2=O)c3ccc(cc3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D19 compound treatment 721071.0 479000.0 0.99 709979.0 474000.0 1.03 1.4239 0.9998 1624050 CBMicro_001357 Cn1c(Sc2nc3ccccc3o2)nc4n(C)c(=O)n(C)c(=O)c14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D20 compound treatment 711329.0 469000.0 0.97 685461.0 449000.0 0.97 1.3721 1.0 1923980 CBMicro_001358 [O-][N+](=O)c1ccc(cc1)C(=O)C(=C2Nc3ccccc3N2)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D21 compound treatment 719824.0 478000.0 0.99 724074.0 488000.0 1.06 1.4436 0.9994 1134339 CBMicro_001359 COc1ccc(cc1)N(CC(=O)NCc2ccncc2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D22 compound treatment 698752.0 457000.0 0.94 667511.0 431000.0 0.93 1.3263 1.0 1923981 CBMicro_001360 COc1ccc(OCC(=O)Nc2cccc(c2)C(=O)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D23 mock treatment 683398.0 441000.0 0.91 663879.0 428000.0 0.93 1.2983 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 D24 mock treatment 222711.0 -19500.0 -0.04 246932.0 10600.0 0.02 -0.0122 -0.2639 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E01 mock treatment 16053.0 -226000.0 -0.47 14346.0 -222000.0 -0.48 -0.6699 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E02 mock treatment 15393.0 -227000.0 -0.47 14890.0 -221000.0 -0.48 -0.67 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E03 compound treatment 766693.0 524000.0 1.08 761072.0 525000.0 1.14 1.5687 0.9997 1923982 CBMicro_001361 OC(=O)COc1ccccc1/C=C\2/SC(=S)N(NC(=O)c3ccc(Cl)cc3)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E04 compound treatment 657640.0 415000.0 0.86 634421.0 398000.0 0.86 1.2157 1.0 1923983 CBMicro_001362 Clc1ccccc1OCCNC(=O)C(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E05 compound treatment 704820.0 463000.0 0.95 735940.0 500000.0 1.08 1.4399 0.9981 1505278 CBMicro_001363 COc1ccc(CC(=O)NC2C3CC4CC(C3)CC2C4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E06 compound treatment 682639.0 440000.0 0.91 644311.0 408000.0 0.88 1.2673 0.9999 1552159 CBMicro_001364 COc1cc(cc(OC)c1OC)C(=O)NCc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E07 compound treatment 735077.0 493000.0 1.02 685354.0 449000.0 0.97 1.4066 0.9997 1717978 CBMicro_001365 C1Oc2ccccc2OC1c3[nH]nc(c3c4nc5ccccc5[nH]4)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E08 compound treatment 701199.0 459000.0 0.95 685929.0 450000.0 0.97 1.3581 0.9999 1923984 CBMicro_001366 Clc1ccc(cc1)C2c3c(Oc4c2c(=O)oc5ccccc45)c6ccccc6oc3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E09 compound treatment 719980.0 478000.0 0.99 690266.0 454000.0 0.98 1.3921 1.0 1923985 CBMicro_001367 COc1ccc(C)cc1NC(=O)C(=O)NCCCO 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E10 compound treatment 700965.0 459000.0 0.95 683708.0 447000.0 0.97 1.3543 0.9999 1923986 CBMicro_001368 Cc1occc1C(=O)Nc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E11 compound treatment 757332.0 515000.0 1.06 687336.0 451000.0 0.98 1.4422 0.9991 1462071 CBMicro_001369 COc1cc(cc(OC)c1OC)C(=O)N2CCN(CC2)C(=O)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E12 compound treatment 718580.0 476000.0 0.98 695405.0 459000.0 0.99 1.3979 1.0 1282005 CBMicro_001370 CCSc1nc2ccccc2n1CC(=O)Nc3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E13 compound treatment 779242.0 537000.0 1.11 688223.0 452000.0 0.98 1.4755 0.9981 1923987 CBMicro_001371 Cc1cc(co1)C(=O)Nc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E14 compound treatment 720576.0 478000.0 0.99 681059.0 445000.0 0.96 1.3789 0.9999 1637620 CBMicro_001372 CCc1nc2ccc(Oc3ccc4nc(CC)[nH]c4c3)cc2[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E15 compound treatment 722329.0 480000.0 0.99 705702.0 469000.0 1.02 1.4192 0.9999 1923988 CBMicro_001373 [O-][N+](=O)c1ccc(cc1)n2cccc2/C=C/3\C(=O)NN(C3=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E16 compound treatment 747691.0 505000.0 1.04 688439.0 452000.0 0.98 1.4298 0.9995 1632686 CBMicro_001374 O=C(Nc1nccs1)c2cccc(c2)N3C(=O)c4ccccc4C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E17 compound treatment 746391.0 504000.0 1.04 695690.0 459000.0 0.99 1.439 0.9997 1923989 CBMicro_001375 Fc1ccccc1OCCNC(=O)c2ccc(F)c3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E18 compound treatment 1057516.0 815000.0 1.68 998580.0 762000.0 1.65 2.3567 1.0 1923990 CBMicro_001376 COC(=O)c1ccc(cc1)n2c(C)cc(/C=C/3\S\C(=N/C(=O)C)\NC3=O)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E19 compound treatment 739907.0 498000.0 1.03 709520.0 473000.0 1.02 1.4507 1.0 1923991 CBMicro_001377 CCNC(=O)CCC(=O)Nc1cc(Cl)ccc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E20 compound treatment 720388.0 478000.0 0.99 668783.0 432000.0 0.94 1.3598 0.9996 1923992 CBMicro_001378 CCCc1c(O)nc(SCCN2CCOCC2)n(c3ccccc3)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E21 compound treatment 731738.0 490000.0 1.01 685944.0 450000.0 0.97 1.4027 0.9998 1923993 CBMicro_001379 CC(C)c1ccc(C)cc1OCCNC(=O)c2ccc(Cl)cc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E22 compound treatment 710058.0 468000.0 0.97 659060.0 423000.0 0.91 1.3299 0.9996 1157580 CBMicro_001380 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)COc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E23 mock treatment 691567.0 449000.0 0.93 682741.0 446000.0 0.97 1.3391 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 E24 mock treatment 233968.0 -8260.0 -0.02 282044.0 45700.0 0.1 0.0579 0.5768 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F01 mock treatment 15445.0 -227000.0 -0.47 14607.0 -222000.0 -0.48 -0.6703 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F02 mock treatment 14786.0 -227000.0 -0.47 14817.0 -221000.0 -0.48 -0.671 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F03 compound treatment 609891.0 368000.0 0.76 608641.0 372000.0 0.81 1.1065 0.9996 1923994 CBMicro_001381 CCc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F04 compound treatment 677564.0 435000.0 0.9 717027.0 481000.0 1.04 1.3712 0.9973 1198795 CBMicro_001382 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F05 compound treatment 706564.0 464000.0 0.96 675042.0 439000.0 0.95 1.3492 1.0 1923995 CBMicro_001383 Clc1ccc(cc1)c2noc(n2)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F06 compound treatment 688537.0 446000.0 0.92 685408.0 449000.0 0.97 1.3388 0.9996 1923996 CBMicro_001384 [O-][N+](=O)c1ccc(cc1)C2=NNC(=O)C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F07 compound treatment 743311.0 501000.0 1.03 725288.0 489000.0 1.06 1.4798 0.9999 1516787 CBMicro_001385 CCC(=O)OCCn1c(=O)c2ccccc2c3ccccc3c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F08 compound treatment 699908.0 458000.0 0.94 711603.0 475000.0 1.03 1.3955 0.9991 1923997 CBMicro_001386 CCc1ccccc1NC(=O)CC2S/C(=N\N=C(/C)\C=C\c3ccc(OC)cc3)/N=C2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F09 compound treatment 709755.0 468000.0 0.97 781716.0 545000.0 1.18 1.5172 0.995 1923998 CBMicro_001387 CC/1=NN(C(=O)\C1=C/c2ccc3OCOc3c2)c4nc(cs4)c5ccc(Br)cc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F10 compound treatment 701500.0 459000.0 0.95 728012.0 492000.0 1.06 1.4229 0.9983 1373731 CBMicro_001388 Cc1onc(c1C(=O)Nc2ccc(O)c(c2)C(=O)O)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F11 compound treatment 723738.0 482000.0 0.99 796753.0 560000.0 1.21 1.5606 0.9951 1700563 CBMicro_001389 COc1cc(cc(OC)c1OC)C(=O)c2cc(Br)ccc2NC(=O)COc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F12 compound treatment 695825.0 454000.0 0.94 716123.0 480000.0 1.04 1.3964 0.9987 1923999 CBMicro_001390 C/C(=N\N=C\1/SC(CC(=O)Nc2ccc(C)c(Cl)c2)C(=N1)O)/c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F13 compound treatment 725763.0 484000.0 1.0 728002.0 492000.0 1.06 1.4583 0.9995 1924000 CBMicro_001391 Cc1cc(C)cc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F14 compound treatment 700339.0 458000.0 0.95 720157.0 484000.0 1.05 1.4092 0.9987 1924001 CBMicro_001392 COc1cc(CC=C)ccc1OCCCCN2CCC(C)CC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F15 compound treatment 745618.0 503000.0 1.04 759728.0 523000.0 1.13 1.5358 0.9991 1124518 CBMicro_001393 CCCOc1ccc(cc1)C(=O)Nc2ccccc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F16 compound treatment 703438.0 461000.0 0.95 720141.0 484000.0 1.05 1.4137 0.9989 1924002 CBMicro_001394 CCCOc1ccc2ccc(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F17 compound treatment 760225.0 518000.0 1.07 751090.0 515000.0 1.11 1.544 0.9998 1924003 CBMicro_001395 COc1cccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F18 compound treatment 696508.0 454000.0 0.94 697510.0 461000.0 1.0 1.3689 0.9995 1924004 CBMicro_001396 COc1ccc(cc1)C2=N/C(=C/c3ccc(cc3)[N+](=O)[O-])/C(=O)N2c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F19 compound treatment 728507.0 486000.0 1.0 731878.0 496000.0 1.07 1.4682 0.9995 1783979 CBMicro_001397 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F20 compound treatment 700721.0 458000.0 0.95 682794.0 446000.0 0.97 1.3526 0.9999 1924005 CBMicro_001398 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2)C(=N1)O)/c3ccc(O)cc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F21 compound treatment 722129.0 480000.0 0.99 692256.0 456000.0 0.99 1.3983 1.0 1549085 CBMicro_001399 CCCC1C(NC(C(C)C1(O)CCC)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F22 compound treatment 685510.0 443000.0 0.92 698399.0 462000.0 1.0 1.3542 0.999 1924006 CBMicro_001400 COc1ccc(CC(=O)O/N=C(\N)/Cc2ccc(cc2)[N+](=O)[O-])cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F23 mock treatment 702328.0 460000.0 0.95 664108.0 428000.0 0.93 1.3263 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 F24 mock treatment 212533.0 -29700.0 -0.06 230073.0 -6240.0 -0.01 -0.0529 -0.8428 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G01 mock treatment 15456.0 -227000.0 -0.47 14409.0 -222000.0 -0.48 -0.6706 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G02 mock treatment 15194.0 -227000.0 -0.47 13456.0 -223000.0 -0.48 -0.6725 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G03 compound treatment 680565.0 438000.0 0.9 656134.0 420000.0 0.91 1.2823 1.0 1608881 CBMicro_001401 Cc1cc2ncn(CC(O)COc3ccc4ccccc4c3)c2cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G04 compound treatment 680795.0 439000.0 0.91 735997.0 500000.0 1.08 1.4049 0.9961 1924007 CBMicro_001402 COc1cccc(/C=N/N2C(=O)c3cccc4cccc(C2=O)c34)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G05 compound treatment 691622.0 449000.0 0.93 681392.0 445000.0 0.96 1.3371 0.9998 1924008 CBMicro_001403 Cc1cccc(N2C(=O)C(=C(Nc3ccccc3C)C2=O)Cl)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G06 compound treatment 676600.0 434000.0 0.9 643302.0 407000.0 0.88 1.2569 1.0 1924009 CBMicro_001404 Cc1ccc(OCCNC(=O)Cc2cccc3ccccc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G07 compound treatment 724482.0 482000.0 1.0 685632.0 449000.0 0.97 1.3916 0.9999 1924010 CBMicro_001405 C/C(=N\N=C\1/SC(CC(=O)Nc2cccc(C)c2C)C(=N1)O)/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G08 compound treatment 716127.0 474000.0 0.98 681766.0 445000.0 0.96 1.3735 1.0 1924011 CBMicro_001406 OC(=O)CC1S/C(=N\N=C/C=C\c2ccccc2)/N(C1=O)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G09 compound treatment 730492.0 488000.0 1.01 704985.0 469000.0 1.01 1.43 1.0 1924012 CBMicro_001407 COc1ccc(CCNC(=O)C(=O)NCc2ccco2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G10 compound treatment 699786.0 458000.0 0.94 688336.0 452000.0 0.98 1.3597 0.9998 1151591 CBMicro_001408 CC(SCC(=O)Nc1ccc2ccccc2c1)C(=O)Nc3c(C)cc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G11 compound treatment 760998.0 519000.0 1.07 708681.0 472000.0 1.02 1.4802 0.9997 1924013 CBMicro_001409 COc1ccc(Cl)cc1N(CC(=O)NC(C)(C)C#C)S(=O)(=O)c2ccc(C)c(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G12 compound treatment 724879.0 483000.0 1.0 692440.0 456000.0 0.99 1.4026 1.0 1924014 CBMicro_001410 O=c1[nH]cnc2scc(c3ccc(cc3)c4ccccc4)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G13 compound treatment 736226.0 494000.0 1.02 690444.0 454000.0 0.98 1.4161 0.9998 1374658 CBMicro_001411 Brc1ccc(NC(=O)CSc2nc(c[nH]2)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G14 compound treatment 724090.0 482000.0 0.99 692927.0 457000.0 0.99 1.4022 1.0 1924015 CBMicro_001412 Cc1cc(C=O)c(C)n1c2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G15 compound treatment 750798.0 509000.0 1.05 734262.0 498000.0 1.08 1.5044 0.9999 1924016 CBMicro_001413 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G16 compound treatment 701638.0 459000.0 0.95 649178.0 413000.0 0.89 1.3025 0.9996 1529615 CBMicro_001414 Cc1cccc(C)c1OCC(O)Cn2c3ccccc3c4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G17 compound treatment 744341.0 502000.0 1.04 687871.0 452000.0 0.98 1.424 0.9996 1924017 CBMicro_001415 Cc1ccccc1OCCNC(=O)Cc2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G18 compound treatment 712690.0 470000.0 0.97 690661.0 454000.0 0.98 1.3821 1.0 1924018 CBMicro_001416 Brc1ccc2nc(/C=C\c3ccccc3)oc(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G19 compound treatment 763340.0 521000.0 1.08 722714.0 486000.0 1.05 1.5051 0.9999 1924019 CBMicro_001417 CCCCOc1ccc(NC(=O)CSCC(=O)Nc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G20 compound treatment 1115956.0 874000.0 1.8 672442.0 436000.0 0.94 1.9428 0.9544 1924020 CBMicro_001418 COc1ccc(CNC(=S)Nc2ccc(Cl)cc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G21 compound treatment 733987.0 492000.0 1.02 681282.0 445000.0 0.96 1.3988 0.9997 1924021 CBMicro_001419 CCOc1ccc(NC(=O)COc2ccccc2)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G22 compound treatment 703279.0 461000.0 0.95 680507.0 444000.0 0.96 1.3528 1.0 1641895 CBMicro_001420 CCC(C)NCC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G23 mock treatment 699345.0 457000.0 0.94 655536.0 419000.0 0.91 1.3088 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 G24 mock treatment 181872.0 -60400.0 -0.12 293384.0 57100.0 0.12 -8.0E-4 -0.0043 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H01 mock treatment 15110.0 -227000.0 -0.47 14471.0 -222000.0 -0.48 -0.671 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H02 mock treatment 15341.0 -227000.0 -0.47 12963.0 -223000.0 -0.48 -0.673 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H03 compound treatment 637467.0 395000.0 0.82 669967.0 434000.0 0.94 1.2406 0.9976 1323349 CBMicro_001421 CC(C)(C)C(=O)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H04 compound treatment 641629.0 399000.0 0.82 681112.0 445000.0 0.96 1.2637 0.997 1924022 CBMicro_001422 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccccc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H05 compound treatment 646504.0 404000.0 0.83 685374.0 449000.0 0.97 1.2774 0.9971 1671033 CBMicro_001423 COC(=O)c1cccc(NC(=O)C2(CC3CC4C2)CC(C3)(C4)C(=O)Nc5cccc(c5)C(=O)OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H06 compound treatment 660210.0 418000.0 0.86 683335.0 447000.0 0.97 1.2943 0.9984 1924023 CBMicro_001424 CC(C)n1c(S)nc2n(C)c(=O)n(C)c(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H07 compound treatment 691572.0 449000.0 0.93 699826.0 464000.0 1.0 1.3653 0.9992 1619510 CBMicro_001425 COc1ccc(cc1)C(=O)N2CCN(CC2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H08 compound treatment 661558.0 419000.0 0.87 674411.0 438000.0 0.95 1.2826 0.999 1924024 CBMicro_001426 Clc1ccc(cc1)c2csc(NC(=O)c3cccs3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H09 compound treatment 722924.0 481000.0 0.99 717746.0 481000.0 1.04 1.4385 0.9997 1924025 CBMicro_001427 COc1cccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)c(C)c3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H10 compound treatment 680665.0 438000.0 0.91 696709.0 460000.0 1.0 1.3446 0.9988 1924026 CBMicro_001428 CC(=O)Nc1cc(n[nH]1)c2ccc(C)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H11 compound treatment 697142.0 455000.0 0.94 711204.0 475000.0 1.03 1.3908 0.999 1924027 CBMicro_001429 COc1ccc(OC)c(/C=C/C(=O)c2c(c3ccccc3)c4cc(Br)ccc4[nH]c2=O)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H12 compound treatment 704403.0 462000.0 0.95 671594.0 435000.0 0.94 1.3408 1.0 1924028 CBMicro_001430 Cc1ccccc1OCc2nc(no2)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H13 compound treatment 766243.0 524000.0 1.08 692539.0 456000.0 0.99 1.4631 0.999 1580566 CBMicro_001431 COc1cc(NC(=O)C(c2ccccc2)c3ccccc3)cc(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H14 compound treatment 705098.0 463000.0 0.96 715491.0 479000.0 1.04 1.409 0.9992 1382396 CBMicro_001432 COC(=O)c1ccc(COc2ccc3c(c2)oc(=O)c4ccccc43)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H15 compound treatment 727398.0 485000.0 1.0 706295.0 470000.0 1.02 1.4275 1.0 1590353 CBMicro_001433 Cc1nccn1CC(=O)N2c3ccccc3Sc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H16 compound treatment 702220.0 460000.0 0.95 702813.0 466000.0 1.01 1.3854 0.9995 1160031 CBMicro_001434 Cc1cc(Cl)ccc1OCC(=O)NCCc2nc3ccccc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H17 compound treatment 712669.0 470000.0 0.97 753101.0 517000.0 1.12 1.4776 0.9975 1417405 CBMicro_001435 Clc1ccc(CSc2nc3cccnc3[nH]2)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H18 compound treatment 691002.0 449000.0 0.93 714336.0 478000.0 1.03 1.3867 0.9985 1200802 CBMicro_001436 CC(C)(C)c1ccc(Oc2coc3c(CN4CCOCC4)c(O)ccc3c2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H19 compound treatment 887378.0 645000.0 1.33 874187.0 638000.0 1.38 1.9179 0.9998 1924029 CBMicro_001437 Nc1c(C#N)c(nn1c2ccccc2)/C(=C/c3ccc(o3)c4ccccc4F)/C#N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H20 compound treatment 669085.0 427000.0 0.88 681107.0 445000.0 0.96 1.3038 0.999 1924030 CBMicro_001438 COc1ccc(cc1)/C(=N/N=C/2\SC(CC(=O)Nc3cccc(c3)[N+](=O)[O-])C(=N2)O)/C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H21 compound treatment 714087.0 472000.0 0.97 704635.0 468000.0 1.01 1.4055 0.9998 1924031 CBMicro_001439 COc1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)ccc1OCCOc4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H22 compound treatment 675827.0 434000.0 0.9 681925.0 446000.0 0.96 1.3149 0.9993 1924032 CBMicro_001440 COCCCNC(=O)COc1ccc2ccccc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H23 mock treatment 683379.0 441000.0 0.91 661014.0 425000.0 0.92 1.2939 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 H24 mock treatment 213161.0 -29100.0 -0.06 203056.0 -33300.0 -0.07 -0.0933 -0.9959 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I01 mock treatment 15634.0 -227000.0 -0.47 14429.0 -222000.0 -0.48 -0.6703 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I02 mock treatment 13854.0 -228000.0 -0.47 13414.0 -223000.0 -0.48 -0.6745 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I03 compound treatment 688140.0 446000.0 0.92 702256.0 466000.0 1.01 1.364 0.999 1283754 CBMicro_001441 CC1(C)CC(CC(C)(C)N1)NC(=S)Nc2ccc(F)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I04 compound treatment 666746.0 425000.0 0.88 643954.0 408000.0 0.88 1.2435 1.0 1924033 CBMicro_001442 Cc1cc(C)c(OCC(=O)Nc2cccc(c2)[N+](=O)[O-])c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I05 compound treatment 680421.0 438000.0 0.9 709197.0 473000.0 1.02 1.3633 0.9981 1924034 CBMicro_001443 COC(=O)CCN1C(=O)/C(=C/c2ccc(OCc3ccc(Cl)cc3)c(OC)c2)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I06 compound treatment 675643.0 433000.0 0.89 670456.0 434000.0 0.94 1.2971 0.9997 1924035 CBMicro_001444 Cc1cccc(C)c1NC(=O)CSc2nnc(c3ccco3)n2c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I07 compound treatment 704013.0 462000.0 0.95 675685.0 439000.0 0.95 1.3465 1.0 1924036 CBMicro_001445 CCc1ccc(/C=C/2\N(C(=O)C)C(=O)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I08 compound treatment 746546.0 504000.0 1.04 794674.0 558000.0 1.21 1.5907 0.9972 1924037 CBMicro_001446 COc1ccc(cc1)C2=N/C(=C/c3ccc(F)cc3)/C(=O)N2c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I09 compound treatment 733674.0 491000.0 1.01 683345.0 447000.0 0.97 1.4015 0.9997 1924038 CBMicro_001447 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I10 compound treatment 694368.0 452000.0 0.93 698116.0 462000.0 1.0 1.3667 0.9994 1212986 CBMicro_001448 Cc1cc(C)c(OCC(=O)Nc2ccc(Br)cc2)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I11 compound treatment 1431192.0 1190000.0 2.45 1260537.0 1020000.0 2.22 3.303 0.9987 1221965 CBMicro_001449 COc1ccc(c(N)c1)n2c(C)ccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I12 compound treatment 853513.0 611000.0 1.26 803855.0 568000.0 1.23 1.7609 0.9999 1924039 CBMicro_001450 COc1cc(/C=C/2\SC(=S)N(C(CCC(=O)O)C(=O)O)C2=O)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I13 compound treatment 761497.0 519000.0 1.07 720641.0 484000.0 1.05 1.4992 0.9999 1924040 CBMicro_001451 Brc1ccc2nc(SCC(=O)NCCOc3ccccc3)n(c4ccccc4)c(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I14 compound treatment 738616.0 496000.0 1.02 701194.0 465000.0 1.01 1.436 1.0 1924041 CBMicro_001452 COc1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)cc(Br)c1OCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I15 compound treatment 770156.0 528000.0 1.09 711062.0 475000.0 1.03 1.4972 0.9996 1180086 CBMicro_001453 COc1ccc(cc1)S(=O)(=O)N2CCN(CC2)S(=O)(=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I16 compound treatment 721941.0 480000.0 0.99 664995.0 429000.0 0.93 1.3563 0.9995 1727208 CBMicro_001454 Brc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)c(c1)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I17 compound treatment 803313.0 561000.0 1.16 720404.0 484000.0 1.05 1.5599 0.9987 1924042 CBMicro_001455 COc1ccccc1OCCNC(=O)c2ccccc2I 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I18 compound treatment 712679.0 470000.0 0.97 698737.0 462000.0 1.0 1.3944 0.9999 1783640 CBMicro_001456 OC(=O)CCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I19 compound treatment 815759.0 574000.0 1.18 705000.0 469000.0 1.01 1.5545 0.997 1924043 CBMicro_001457 [O-][N+](=O)c1cccc(/C=C/2\N=C(OC2=O)c3ccccc3F)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I20 compound treatment 719872.0 478000.0 0.99 725053.0 489000.0 1.06 1.4452 0.9994 1508030 CBMicro_001458 Clc1ccc(OCC(=O)N2CCN(CC2)C(=O)c3ccncc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I21 compound treatment 734177.0 492000.0 1.02 711985.0 476000.0 1.03 1.4461 1.0 1617393 CBMicro_001459 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Cl)cn2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I22 compound treatment 705088.0 463000.0 0.96 657063.0 421000.0 0.91 1.3196 0.9997 1924044 CBMicro_001460 Brc1ccc(NC(=O)CNC(=O)CN2CCOCC2)c(c1)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I23 mock treatment 695390.0 453000.0 0.94 665665.0 429000.0 0.93 1.3186 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 I24 mock treatment 239330.0 -2900.0 -0.01 265383.0 29100.0 0.06 0.0403 0.637 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J01 mock treatment 14901.0 -227000.0 -0.47 14367.0 -222000.0 -0.48 -0.6715 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J02 mock treatment 14838.0 -227000.0 -0.47 12367.0 -224000.0 -0.48 -0.6747 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J03 compound treatment 646127.0 404000.0 0.83 669609.0 433000.0 0.94 1.2527 0.9983 1924045 CBMicro_001461 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2C)C(=N1)O)/c3ccco3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J04 compound treatment 692758.0 451000.0 0.93 650794.0 414000.0 0.9 1.292 0.9998 1924046 CBMicro_001462 COc1cc(/C=C\2/C(=NN(C2=O)c3nc(cs3)c4ccc(Cl)cc4)C)cc(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J05 compound treatment 681458.0 439000.0 0.91 676097.0 440000.0 0.95 1.3142 0.9997 1194890 CBMicro_001463 Cc1c(OCc2ccccc2)ccc3c4CCCc4c(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J06 compound treatment 656415.0 414000.0 0.86 672306.0 436000.0 0.94 1.2718 0.9988 1122070 CBMicro_001464 CCOC(=O)c1cnc2cc(nn2c1O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J07 compound treatment 770846.0 529000.0 1.09 777697.0 541000.0 1.17 1.6002 0.9994 1456980 CBMicro_001465 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J08 compound treatment 666189.0 424000.0 0.88 684489.0 448000.0 0.97 1.3048 0.9987 1924047 CBMicro_001466 FC(F)C(F)(F)COS(=O)(=O)CCN1C(=O)c2cccc3cccc(C1=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J09 compound treatment 703638.0 461000.0 0.95 706357.0 470000.0 1.02 1.3929 0.9995 1357024 CBMicro_001467 CCCc1cc(O)n2nc(cc2n1)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J10 compound treatment 668501.0 426000.0 0.88 676320.0 440000.0 0.95 1.2956 0.9992 1924048 CBMicro_001468 OCc1ccccc1NC(=O)/C=C/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J11 compound treatment 689457.0 447000.0 0.92 702056.0 466000.0 1.01 1.3656 0.999 1924049 CBMicro_001469 [O-][N+](=O)c1ccc(cc1)C2Nc3ccc(cc3NC4=C2C(=O)CC(C4)c5ccccc5)C(=O)c6ccccc6 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J12 compound treatment 676519.0 434000.0 0.9 725457.0 489000.0 1.06 1.3825 0.9966 1644344 CBMicro_001470 Cc1ccc2nc(C)c(CN3CCOCC3)c(O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J13 compound treatment 716282.0 474000.0 0.98 694438.0 458000.0 0.99 1.3931 1.0 1924050 CBMicro_001471 COC(=O)C/1=C(C)N(C(=O)\C1=C/c2ccccc2[N+](=O)[O-])c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J14 compound treatment 701465.0 459000.0 0.95 682461.0 446000.0 0.97 1.3531 1.0 1502705 CBMicro_001472 O=C(NC(=S)Nc1cccc(c1)c2nc3ccccc3o2)c4ccco4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J15 compound treatment 724422.0 482000.0 1.0 703874.0 468000.0 1.01 1.4194 1.0 1924051 CBMicro_001473 Brc1ccc2c(c1)c(nc3nnnn32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J16 compound treatment 725976.0 484000.0 1.0 698611.0 462000.0 1.0 1.4136 1.0 1268616 CBMicro_001474 Brc1ccccc1Oc2coc3cc(OC(=O)c4ccco4)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J17 compound treatment 718168.0 476000.0 0.98 718334.0 482000.0 1.04 1.4324 0.9996 1924052 CBMicro_001475 Oc1cc(nc2cc(nn12)c3cccs3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J18 compound treatment 714045.0 472000.0 0.97 701623.0 465000.0 1.01 1.4008 0.9999 1238170 CBMicro_001476 Cc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J19 compound treatment 716931.0 475000.0 0.98 724672.0 488000.0 1.06 1.4403 0.9993 1301872 CBMicro_001477 CCOC(=O)c1cnc2cc(nn2c1O)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J20 compound treatment 690622.0 448000.0 0.93 678540.0 442000.0 0.96 1.3313 0.9999 1924053 CBMicro_001478 COc1ccc(/C=C/C(=O)c2c(O)c(OC)c3occc3c2OC)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J21 compound treatment 702833.0 461000.0 0.95 721951.0 486000.0 1.05 1.4156 0.9987 1363778 CBMicro_001479 Cc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NCc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J22 compound treatment 680191.0 438000.0 0.9 639456.0 403000.0 0.87 1.2563 0.9998 1924054 CBMicro_001480 N/C(=N\OC(=O)C(c1ccccc1)c2ccccc2)/c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J23 mock treatment 676955.0 435000.0 0.9 669386.0 433000.0 0.94 1.2974 0.9998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 J24 mock treatment 288641.0 46400.0 0.1 202605.0 -33700.0 -0.07 0.0162 0.1342 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K01 mock treatment 15037.0 -227000.0 -0.47 14199.0 -222000.0 -0.48 -0.6716 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K02 mock treatment 14555.0 -228000.0 -0.47 13665.0 -223000.0 -0.48 -0.6731 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K03 compound treatment 667400.0 425000.0 0.88 653588.0 417000.0 0.9 1.2592 0.9999 1551601 CBMicro_001481 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K04 compound treatment 667996.0 426000.0 0.88 622151.0 386000.0 0.84 1.212 0.9997 1924055 CBMicro_001482 CCS(=O)(=O)c1nnnn1c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K05 compound treatment 683612.0 441000.0 0.91 670596.0 434000.0 0.94 1.3089 0.9999 1241998 CBMicro_001483 COc1ccc(Nc2ncnc3ccc(C)cc23)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K06 compound treatment 659668.0 417000.0 0.86 585436.0 349000.0 0.76 1.1436 0.9979 1924056 CBMicro_001484 CCCCOc1ccc(cc1)C(=O)NCCOc2ccccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K07 compound treatment 700741.0 459000.0 0.95 684664.0 448000.0 0.97 1.3555 0.9999 1617886 CBMicro_001485 CCOC(=O)N1CCN(CC1)C(=O)COc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K08 compound treatment 673272.0 431000.0 0.89 652796.0 416000.0 0.9 1.2666 1.0 1924057 CBMicro_001486 CCOC(=O)C/1=C(C)N(C(=O)\C1=C/c2cccc(OC)c2O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K09 compound treatment 745387.0 503000.0 1.04 672948.0 437000.0 0.95 1.4027 0.9989 1163676 CBMicro_001487 COc1ccc(cc1)C(=O)Oc2cccc3c(OC)ccc(C=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K10 compound treatment 680478.0 438000.0 0.9 667793.0 431000.0 0.93 1.3001 0.9999 1924058 CBMicro_001488 S=C(NCCOc1cccc2ccccc12)Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K11 compound treatment 716468.0 474000.0 0.98 668862.0 433000.0 0.94 1.3542 0.9998 1924059 CBMicro_001489 Cc1ccccc1NC(=O)C(=O)NCCN2CCNCC2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K12 compound treatment 695048.0 453000.0 0.93 649125.0 413000.0 0.89 1.2928 0.9997 1312323 CBMicro_001490 COc1ccccc1c2coc3cc(OCc4ccccc4)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K13 compound treatment 712301.0 470000.0 0.97 686720.0 450000.0 0.97 1.3755 1.0 1924060 CBMicro_001491 Cc1ccc(o1)C(=O)Nc2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K14 compound treatment 752243.0 510000.0 1.05 701041.0 465000.0 1.01 1.4557 0.9997 1924061 CBMicro_001492 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K15 compound treatment 717789.0 476000.0 0.98 692451.0 456000.0 0.99 1.3923 1.0 1924062 CBMicro_001493 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NCCc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K16 compound treatment 719159.0 477000.0 0.98 672062.0 436000.0 0.94 1.3631 0.9998 1924063 CBMicro_001494 Cc1cc(C)nc(NC(=N)Nc2ccc(C)c(c2)[N+](=O)[O-])n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K17 compound treatment 743218.0 501000.0 1.03 685038.0 449000.0 0.97 1.418 0.9995 1924064 CBMicro_001495 CCCCOc1ccc(NC(=O)CSc2nnc(c3cccc(F)c3)n2c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K18 compound treatment 723217.0 481000.0 0.99 686231.0 450000.0 0.97 1.3907 1.0 1924065 CBMicro_001496 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)c3ccccc3n(c4ccccc4)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K19 compound treatment 690845.0 449000.0 0.93 670284.0 434000.0 0.94 1.319 1.0 1924066 CBMicro_001497 CC(C)c1ccc(C)cc1OCCNC(=O)CCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K20 compound treatment 692053.0 450000.0 0.93 661087.0 425000.0 0.92 1.3067 1.0 1924067 CBMicro_001498 Cc1cc(C=O)c(C)n1c2ccc(Cl)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K21 compound treatment 718457.0 476000.0 0.98 692102.0 456000.0 0.99 1.3927 1.0 1924068 CBMicro_001499 Cc1ccc(OCCNC(=O)CCc2ccccc2)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K22 compound treatment 785675.0 543000.0 1.12 707243.0 471000.0 1.02 1.514 0.9989 1924069 CBMicro_001500 CN1C(=O)/C(=C/c2ccc(o2)c3ccc(cc3)C(=O)O)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K23 mock treatment 702312.0 460000.0 0.95 674821.0 439000.0 0.95 1.3427 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 K24 mock treatment 234994.0 -7230.0 -0.01 253309.0 17000.0 0.04 0.0154 0.3892 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L01 mock treatment 14461.0 -228000.0 -0.47 14136.0 -222000.0 -0.48 -0.6725 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L02 mock treatment 14210.0 -228000.0 -0.47 13927.0 -222000.0 -0.48 -0.6732 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L03 compound treatment 640649.0 398000.0 0.82 650666.0 414000.0 0.9 1.2157 0.9991 1175393 CBMicro_001501 Cc1nc2cc(nn2c(O)c1CC=C)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L04 compound treatment 628058.0 386000.0 0.8 634767.0 398000.0 0.86 1.173 0.9992 1629252 CBMicro_001502 Cc1cc(O)n2nc(cc2n1)c3cccs3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L05 compound treatment 670633.0 428000.0 0.88 670065.0 434000.0 0.94 1.2892 0.9996 1240635 CBMicro_001503 Cc1ccc(OCc2nc(no2)c3cccnc3)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L06 compound treatment 679663.0 437000.0 0.9 715253.0 479000.0 1.04 1.3715 0.9976 1924070 CBMicro_001504 Cc1ccc(/C=C\2/N=C(\OC2=O)/C=C/c3ccccc3)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L07 compound treatment 686715.0 444000.0 0.92 664693.0 428000.0 0.93 1.3044 1.0 1186014 CBMicro_001505 CC(=O)Nc1cccc(c1)c2nc3ccccc3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L08 compound treatment 627543.0 385000.0 0.8 609764.0 373000.0 0.81 1.134 1.0 1551067 CBMicro_001506 CCOc1cc2oc(=O)cc(c3ccccc3)c2cc1CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L09 compound treatment 674029.0 432000.0 0.89 681367.0 445000.0 0.96 1.3114 0.9992 1380917 CBMicro_001507 Fc1ccccc1CSc2nc3cccnc3[nH]2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L10 compound treatment 671385.0 429000.0 0.89 665376.0 429000.0 0.93 1.2831 0.9997 1136758 CBMicro_001508 CN(C(=O)COc1ccc2ccccc2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L11 compound treatment 829916.0 588000.0 1.21 836528.0 600000.0 1.3 1.7764 0.9994 1728591 CBMicro_001509 Cc1ccc(C)n1c2ccc(C(=O)O)c(O)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L12 compound treatment 671664.0 429000.0 0.89 647962.0 412000.0 0.89 1.2568 1.0 1651090 CBMicro_001510 CCC(C)NC(=O)COc1ccc2ccccc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L13 compound treatment 725975.0 484000.0 1.0 692481.0 456000.0 0.99 1.4043 1.0 1924071 CBMicro_001511 [O-][N+](=O)c1c(NC2CCCCC2)c3ccccc3n(c4ccccc4)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L14 compound treatment 684217.0 442000.0 0.91 677959.0 442000.0 0.96 1.3211 0.9997 1924072 CBMicro_001512 CC(=O)COc1ccc2c3ccccc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L15 compound treatment 728898.0 487000.0 1.0 697158.0 461000.0 1.0 1.4157 1.0 1924073 CBMicro_001513 COc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)c3ccccc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L16 compound treatment 681252.0 439000.0 0.91 701557.0 465000.0 1.01 1.3529 0.9986 1924074 CBMicro_001514 COC(=O)C1=C(C)N(/C(=C\c2sccc2C)/C1=O)c3ccc(C)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L17 compound treatment 724650.0 482000.0 1.0 688867.0 453000.0 0.98 1.3968 1.0 1924075 CBMicro_001515 Cc1nnc2[nH]c(nn12)c3cccc(Cl)c3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L18 compound treatment 665665.0 423000.0 0.87 671431.0 435000.0 0.94 1.284 0.9993 1924076 CBMicro_001516 Brc1ccc(SC(C(=O)c2ccccc2)C(=O)c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L19 compound treatment 736777.0 495000.0 1.02 702348.0 466000.0 1.01 1.4351 1.0 1924077 CBMicro_001517 Oc1cccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L20 compound treatment 684334.0 442000.0 0.91 675827.0 440000.0 0.95 1.318 0.9998 1924078 CBMicro_001518 COc1ccc(/C=N/N=C\2/SC(CC(=O)O)C(=O)N2c3ccc(O)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L21 compound treatment 700873.0 459000.0 0.95 716086.0 480000.0 1.04 1.4037 0.9989 1132606 CBMicro_001519 Cc1ccc(OCC(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L22 compound treatment 687595.0 445000.0 0.92 701618.0 465000.0 1.01 1.3622 0.999 1924079 CBMicro_001520 CCC(=O)Nc1cccc2C(=O)c3ccccc3C(=O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L23 mock treatment 679908.0 438000.0 0.9 661622.0 425000.0 0.92 1.2898 1.0 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 L24 mock treatment 233444.0 -8780.0 -0.02 196228.0 -40100.0 -0.09 -0.0742 -0.8368 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M01 mock treatment 15142.0 -227000.0 -0.47 14251.0 -222000.0 -0.48 -0.6713 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M02 mock treatment 14838.0 -227000.0 -0.47 12932.0 -223000.0 -0.48 -0.6738 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M03 compound treatment 682973.0 441000.0 0.91 674934.0 439000.0 0.95 1.3146 0.9998 1154345 CBMicro_001521 Cc1ccc(c2ccccc2)n1c3ccccc3C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M04 compound treatment 637446.0 395000.0 0.82 642907.0 407000.0 0.88 1.1992 0.9993 1172278 CBMicro_001522 Brc1ccc2nc(SCC(=O)NC3CCCC3)n(c4ccccc4)c(=O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M05 compound treatment 795827.0 554000.0 1.14 677017.0 441000.0 0.95 1.4826 0.996 1924080 CBMicro_001523 CC(=O)c1c(OC(=O)c2ccc(Cl)cc2[N+](=O)[O-])ccc3c(C)cc(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M06 compound treatment 668806.0 427000.0 0.88 645427.0 409000.0 0.89 1.2488 1.0 1720980 CBMicro_001524 CC(C)c1ccc(C)cc1OCCN 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M07 compound treatment 679989.0 438000.0 0.9 688768.0 452000.0 0.98 1.3315 0.9992 1924081 CBMicro_001525 Cc1cccc(c1)C2=N/C(=C/c3ccc(cc3)[N+](=O)[O-])/C(=O)N2c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M08 compound treatment 668297.0 426000.0 0.88 657421.0 421000.0 0.91 1.2664 0.9998 1304978 CBMicro_001526 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cc(OC)c(OC)c(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M09 compound treatment 690044.0 448000.0 0.92 667534.0 431000.0 0.93 1.3136 1.0 1874329 CBMicro_001527 CSc1ccccc1NC(=O)c2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M10 compound treatment 668376.0 426000.0 0.88 660780.0 424000.0 0.92 1.2717 0.9998 1122251 CBMicro_001528 COc1cc(cc(OC)c1OC)C(=O)Nc2ccccc2OC(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M11 compound treatment 707652.0 465000.0 0.96 683355.0 447000.0 0.97 1.3635 1.0 1924082 CBMicro_001529 COc1ccc2/C(=N/OC(=O)c3cccc4ccccc34)/CCc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M12 compound treatment 693719.0 451000.0 0.93 651915.0 416000.0 0.9 1.2951 0.9998 1924083 CBMicro_001530 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M13 compound treatment 704105.0 462000.0 0.95 688591.0 452000.0 0.98 1.3664 0.9999 1924084 CBMicro_001531 Cc1c(NC(=O)CSc2nnc(c3cccc(F)c3)n2c4ccccc4)c(=O)n(c5ccccc5)n1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M14 compound treatment 707683.0 465000.0 0.96 668126.0 432000.0 0.93 1.3403 0.9999 1924085 CBMicro_001532 Cc1cc(C=O)c(C)n1c2ccccc2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M15 compound treatment 701715.0 459000.0 0.95 670111.0 434000.0 0.94 1.3346 1.0 1475759 CBMicro_001533 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M16 compound treatment 757868.0 516000.0 1.06 711240.0 475000.0 1.03 1.4795 0.9998 1924086 CBMicro_001534 [O-][N+](=O)c1ccc2C(=O)N(Cc3cccnc3)C(=O)c4cccc1c42 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M17 compound treatment 716425.0 474000.0 0.98 659118.0 423000.0 0.92 1.3393 0.9994 1924087 CBMicro_001535 Cc1ccc(NC(=S)NCCOc2ccccc2Cc3ccccc3)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M18 compound treatment 691989.0 450000.0 0.93 716750.0 480000.0 1.04 1.3918 0.9984 1295781 CBMicro_001536 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc3cccc4ccccc34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M19 compound treatment 724232.0 482000.0 1.0 683853.0 448000.0 0.97 1.3885 0.9999 1924088 CBMicro_001537 Cc1oc(cc1CSCc2cc(oc2C)C(=O)O)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M20 compound treatment 671693.0 429000.0 0.89 712780.0 476000.0 1.03 1.3561 0.9972 1479096 CBMicro_001538 Clc1ccccc1C(=O)Nc2nc3CCCC(=O)c3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M21 compound treatment 736952.0 495000.0 1.02 698920.0 463000.0 1.0 1.4301 1.0 1924089 CBMicro_001539 Clc1ccc2OC(=O)C(c2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M22 compound treatment 683907.0 442000.0 0.91 660901.0 425000.0 0.92 1.2945 1.0 1266242 CBMicro_001540 Cc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NCc3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M23 mock treatment 679994.0 438000.0 0.9 678026.0 442000.0 0.96 1.315 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 M24 mock treatment 255089.0 12900.0 0.03 176458.0 -59900.0 -0.13 -0.0728 -0.5507 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N01 mock treatment 15508.0 -227000.0 -0.47 14356.0 -222000.0 -0.48 -0.6706 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N02 mock treatment 15351.0 -227000.0 -0.47 12408.0 -224000.0 -0.48 -0.6738 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N03 compound treatment 635791.0 394000.0 0.81 629533.0 393000.0 0.85 1.1763 0.9997 1623239 CBMicro_001541 COc1ccccc1Nc2ncnc3ccc(C)cc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N04 compound treatment 610996.0 369000.0 0.76 632418.0 396000.0 0.86 1.1445 0.9982 1924090 CBMicro_001542 Oc1cc(nc2cc(nn12)c3ccc(F)cc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N05 compound treatment 663692.0 421000.0 0.87 651259.0 415000.0 0.9 1.2503 0.9999 1924091 CBMicro_001543 COc1cc(/C=N/N=C/2\SC(CC(=O)Nc3cccc(Cl)c3Cl)C(=N2)O)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N06 compound treatment 641672.0 399000.0 0.82 648214.0 412000.0 0.89 1.2135 0.9992 1392955 CBMicro_001544 COc1ccc(Br)cc1CN2CCN(CC2)S(=O)(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N07 compound treatment 660259.0 418000.0 0.86 662044.0 426000.0 0.92 1.2618 0.9995 1526525 CBMicro_001545 Cc1cccc(C)c1OCC(=O)Nc2ccc(Br)cc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N08 compound treatment 643138.0 401000.0 0.83 629923.0 394000.0 0.85 1.1876 0.9999 1286923 CBMicro_001546 CCc1ccc(cc1)C(=O)CC2(O)C(=O)Nc3ccccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N09 compound treatment 658358.0 416000.0 0.86 661069.0 425000.0 0.92 1.2575 0.9994 1398555 CBMicro_001547 Cc1ccc(cc1)c2cc3nc(C)c(CC=C)c(O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N10 compound treatment 659808.0 418000.0 0.86 653960.0 418000.0 0.9 1.2487 0.9997 1395324 CBMicro_001548 COc1ccc(cc1OC)C2Nc3ccccc3C(=O)N2c4ccc(Cl)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N11 compound treatment 671898.0 430000.0 0.89 683936.0 448000.0 0.97 1.3122 0.999 1685171 CBMicro_001549 Cc1nc2ccccc2n1CC(O)COc3cccc(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N12 compound treatment 662575.0 420000.0 0.87 632823.0 397000.0 0.86 1.2204 1.0 1611532 CBMicro_001550 Cc1c(OCC(=O)OC(C)(C)C)ccc2c(cc(=O)oc12)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N13 compound treatment 694633.0 452000.0 0.93 658399.0 422000.0 0.91 1.3063 0.9999 1255062 CBMicro_001551 COc1cccc(CN2CCN(Cc3cccn3C)CC2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N14 compound treatment 681050.0 439000.0 0.91 635038.0 399000.0 0.86 1.2508 0.9997 1305094 CBMicro_001552 Cc1nnc(NC(=O)c2ccc(Oc3ccccc3)cc2)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N15 compound treatment 672455.0 430000.0 0.89 681564.0 445000.0 0.96 1.3094 0.9992 1730059 CBMicro_001553 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4cc3OC)cc2)s1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N16 compound treatment 678836.0 437000.0 0.9 655760.0 419000.0 0.91 1.2793 1.0 1475611 CBMicro_001554 COc1ccccc1c2coc3c(CN(C)C)c(O)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N17 compound treatment 689970.0 448000.0 0.92 683205.0 447000.0 0.97 1.3375 0.9997 1787307 CBMicro_001555 CS(=O)(=O)N1CCN(Cc2ccc(cc2)[N+](=O)[O-])CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N18 compound treatment 668167.0 426000.0 0.88 651901.0 416000.0 0.9 1.2578 0.9999 1924092 CBMicro_001556 Fc1ccc(/C=C/2\SC(=S)N(C2=O)c3ccc(Cl)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N19 compound treatment 668056.0 426000.0 0.88 685559.0 449000.0 0.97 1.3091 0.9987 1387139 CBMicro_001557 COc1ccc(NC(=O)CSc2nc(c(o2)c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N20 compound treatment 645488.0 403000.0 0.83 671459.0 435000.0 0.94 1.2546 0.9981 1530842 CBMicro_001558 NS(=O)(=O)c1ccc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N21 compound treatment 681555.0 439000.0 0.91 675090.0 439000.0 0.95 1.3128 0.9997 1435498 CBMicro_001559 CCCC1C(NC(C(C)C1(O)CC=C)c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N22 compound treatment 661254.0 419000.0 0.86 649497.0 413000.0 0.89 1.244 0.9999 1924093 CBMicro_001560 COc1cccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N23 mock treatment 683196.0 441000.0 0.91 681251.0 445000.0 0.96 1.3246 0.9996 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 N24 mock treatment 429495.0 187000.0 0.39 381933.0 146000.0 0.32 0.4962 0.9949 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O01 mock treatment 15393.0 -227000.0 -0.47 14335.0 -222000.0 -0.48 -0.6708 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O02 mock treatment 14995.0 -227000.0 -0.47 12670.0 -224000.0 -0.48 -0.674 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O03 compound treatment 652126.0 410000.0 0.85 633031.0 397000.0 0.86 1.2055 1.0 1592135 CBMicro_001561 Cc1ccc(OCC(=O)Nc2cccc(c2)C(=O)Nc3ccccc3C(=O)O)cc1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O04 compound treatment 623135.0 381000.0 0.79 606206.0 370000.0 0.8 1.1221 1.0 1924094 CBMicro_001562 Clc1ccc(C(=O)NCCOCc2ccccc2)c(Cl)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O05 compound treatment 623091.0 381000.0 0.79 649781.0 413000.0 0.89 1.1887 0.9979 1924095 CBMicro_001563 CC(=O)c1sc(NC(=O)c2ccc(s2)[N+](=O)[O-])nc1c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O06 compound treatment 626374.0 384000.0 0.79 602035.0 366000.0 0.79 1.1204 1.0 1924096 CBMicro_001564 CCCCOc1ccc(NC(=O)CSc2nnnn2c3ccccc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O07 compound treatment 673789.0 432000.0 0.89 644087.0 408000.0 0.88 1.254 1.0 1335943 CBMicro_001565 Cc1ccc2ncnc(Nc3ccc(I)cc3)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O08 compound treatment 634758.0 393000.0 0.81 622725.0 386000.0 0.84 1.1644 0.9999 1149290 CBMicro_001566 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5cccc(OC)c5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O09 compound treatment 643451.0 401000.0 0.83 652725.0 416000.0 0.9 1.223 0.9991 1520192 CBMicro_001567 O=C(COc1ccc2ccccc2c1)NC3C4CC5CC(C4)CC3C5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O10 compound treatment 646486.0 404000.0 0.83 636845.0 401000.0 0.87 1.2031 0.9998 1924097 CBMicro_001568 CCOC(=O)c1c(sc2CCCCc12)n3c(C)cc(/C=C/4\NC(=O)NC4=O)c3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O11 compound treatment 642547.0 400000.0 0.83 657000.0 421000.0 0.91 1.2282 0.9988 1486047 CBMicro_001569 COc1ccc(CN(C)C(=O)c2cccc(c2)C(=O)N(C)Cc3ccc(OC)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O12 compound treatment 650460.0 408000.0 0.84 589564.0 353000.0 0.76 1.1365 0.9988 1924098 CBMicro_001570 CCOc1ccc(NC(=O)CC2S/C(=N\N=C\3/CCCc4ccccc34)/N=C2O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O13 compound treatment 675993.0 434000.0 0.9 636362.0 400000.0 0.87 1.2454 0.9999 1683449 CBMicro_001571 Cc1cc(C)c(OCC(=O)Nc2ccc(I)cc2)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O14 compound treatment 637534.0 395000.0 0.82 623731.0 387000.0 0.84 1.1699 0.9999 1632532 CBMicro_001572 Cc1ccc2nc(cc(c3ccccc3)c2c1)c4ccc(N)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O15 compound treatment 677835.0 436000.0 0.9 670973.0 435000.0 0.94 1.3011 0.9997 1215166 CBMicro_001573 COc1ccccc1N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O16 compound treatment 677221.0 435000.0 0.9 630207.0 394000.0 0.85 1.2378 0.9997 1924099 CBMicro_001574 CCOc1ccc(cc1)n2c(C)cc(C=O)c2C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O17 compound treatment 684382.0 442000.0 0.91 651817.0 416000.0 0.9 1.2813 1.0 1924100 CBMicro_001575 Clc1ccccc1OCCNC(=O)c2cccc3ccccc23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O18 compound treatment 672793.0 431000.0 0.89 658219.0 422000.0 0.91 1.2742 0.9999 1620471 CBMicro_001576 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(F)cc3)c(=O)n2C1c4cccc(OC)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O19 compound treatment 665780.0 424000.0 0.87 769156.0 533000.0 1.15 1.4337 0.9907 1924101 CBMicro_001577 O=C(NCc1ccc2OCOc2c1)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O20 compound treatment 626151.0 384000.0 0.79 648872.0 413000.0 0.89 1.1918 0.9982 1924102 CBMicro_001578 COc1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)ccc1OCC(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O21 compound treatment 672560.0 430000.0 0.89 683921.0 448000.0 0.97 1.3132 0.9991 1924103 CBMicro_001579 Fc1ccccc1C2=N/C(=C\c3ccc(Br)cc3)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O22 compound treatment 641812.0 400000.0 0.82 647158.0 411000.0 0.89 1.212 0.9993 1518249 CBMicro_001580 COC(=O)c1c(NC(=O)COc2ccc(Cl)cc2C)sc3CCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O23 mock treatment 647483.0 405000.0 0.84 649729.0 413000.0 0.89 1.2243 0.9994 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 O24 mock treatment 390635.0 148000.0 0.31 395473.0 159000.0 0.34 0.4602 0.9983 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P01 mock treatment 16199.0 -226000.0 -0.47 14042.0 -222000.0 -0.48 -0.6701 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P02 mock treatment 15958.0 -226000.0 -0.47 15037.0 -221000.0 -0.48 -0.6689 -0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P03 compound treatment 600488.0 358000.0 0.74 564968.0 329000.0 0.71 1.0259 0.9998 1924104 CBMicro_001581 OC(=O)c1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P04 compound treatment 599153.0 357000.0 0.74 565121.0 329000.0 0.71 1.0242 0.9998 1924105 CBMicro_001582 COc1cc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)c(Cl)c3)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P05 compound treatment 593818.0 352000.0 0.73 573431.0 337000.0 0.73 1.0292 1.0 1320648 CBMicro_001583 S=c1[nH]nc(CSc2nc3ccccc3s2)n1c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P06 compound treatment 623473.0 381000.0 0.79 601288.0 365000.0 0.79 1.1151 1.0 1924106 CBMicro_001584 CCCCCCCCn1c(nc2ccccc12)c3nonc3NC(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P07 compound treatment 623196.0 381000.0 0.79 573950.0 338000.0 0.73 1.0728 0.9993 1924107 CBMicro_001585 OC1=N/C(=N/N=C/2\CCCc3ccccc23)/SC1CC(=O)Nc4ccc(Cl)cc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P08 compound treatment 597710.0 355000.0 0.73 577729.0 341000.0 0.74 1.0414 1.0 1924108 CBMicro_001586 CN(C1=NC(=O)/C(=C\C(=C\c2ccc(cc2)[N+](=O)[O-])\Cl)/S1)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P09 compound treatment 613006.0 371000.0 0.77 559528.0 323000.0 0.7 1.0359 0.999 1924109 CBMicro_001587 Cc1ccccc1c2cc3nc(C)c(Cl)c(O)n3n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P10 compound treatment 616436.0 374000.0 0.77 572086.0 336000.0 0.73 1.0601 0.9995 1924110 CBMicro_001588 COc1ccc(cc1)/C(=N/OC(=O)Cc2ccc(OC)c(OC)c2)/N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P11 compound treatment 626118.0 384000.0 0.79 562151.0 326000.0 0.71 1.059 0.9983 1347787 CBMicro_001589 CCCOc1cccc(c1)C(=O)Nc2cccc(c2)C(=O)Nc3ccccc3C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P12 compound treatment 600996.0 359000.0 0.74 561314.0 325000.0 0.7 1.0211 0.9997 1924111 CBMicro_001590 OC(=O)CC1S/C(=N/N=C/c2ccccc2)/N(C1=O)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P13 compound treatment 609153.0 367000.0 0.76 579599.0 343000.0 0.74 1.061 1.0 1515759 CBMicro_001591 COc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NC3CCCCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P14 compound treatment 642758.0 401000.0 0.83 575823.0 340000.0 0.73 1.1042 0.9983 1924112 CBMicro_001592 Cc1ccc(cc1)c2noc(CCc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P15 compound treatment 628680.0 386000.0 0.8 574332.0 338000.0 0.73 1.0814 0.9991 1682933 CBMicro_001593 CC(C)C(=O)Nc1ccc(cc1)C(=O)Nc2ccccc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P16 compound treatment 660869.0 419000.0 0.86 584139.0 348000.0 0.75 1.1434 0.9976 1924113 CBMicro_001594 OC(=O)CC1S/C(=N/N=C/c2ccc(cc2)[N+](=O)[O-])/N(C1=O)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P17 compound treatment 650548.0 408000.0 0.84 601873.0 366000.0 0.79 1.1555 0.9995 1292810 CBMicro_001595 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)cc4Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P18 compound treatment 648393.0 406000.0 0.84 591015.0 355000.0 0.77 1.1357 0.999 1569954 CBMicro_001596 CCc1cc2c(cc(=O)oc2cc1OC(C)C(=O)O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P19 compound treatment 626435.0 384000.0 0.79 618391.0 382000.0 0.83 1.1456 0.9998 1242047 CBMicro_001597 Fc1ccc(CSc2nc3cccnc3[nH]2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P20 compound treatment 633962.0 392000.0 0.81 596376.0 360000.0 0.78 1.1229 0.9998 1554102 CBMicro_001598 CCC(C)C(NC(=O)c1cc(C)oc1C)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P21 compound treatment 698919.0 457000.0 0.94 678140.0 442000.0 0.96 1.3428 1.0 1611699 CBMicro_001599 CCOC(=O)C1=C(N=c2sc(=Cc3ccc(o3)N(C)C)c(=O)n2C1c4ccc(OC)c(OC)c4)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P22 compound treatment 623159.0 381000.0 0.79 601802.0 365000.0 0.79 1.1154 1.0 1924114 CBMicro_001600 Cc1ccc(OCc2nc(no2)c3ccccn3)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P23 mock treatment 617157.0 375000.0 0.77 583538.0 347000.0 0.75 1.0787 0.9999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.690 P24 mock treatment 412007.0 170000.0 0.35 418783.0 182000.0 0.39 0.5271 0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A01 mock treatment 10838.0 -215000.0 -0.44 14147.0 -223000.0 -0.48 -0.6547 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A02 mock treatment 10356.0 -216000.0 -0.45 15100.0 -222000.0 -0.48 -0.6539 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A03 compound treatment 519941.0 294000.0 0.61 627731.0 391000.0 0.85 1.0275 0.9867 1924115 CBMicro_001601 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCC=C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A04 compound treatment 523586.0 298000.0 0.61 585308.0 349000.0 0.75 0.9679 0.9948 1484552 CBMicro_001602 Cc1cc(C)c(NC(=O)c2cncc(Br)c2)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A05 compound treatment 540427.0 314000.0 0.65 599495.0 363000.0 0.79 1.0142 0.9955 1924116 CBMicro_001603 CC(=O)C1(CC(=NN1C(=O)c2ccccc2)C)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A06 compound treatment 544004.0 318000.0 0.66 630652.0 394000.0 0.85 1.0671 0.9917 1561435 CBMicro_001604 CC(C)c1cccc(C(C)C)c1NC(=O)COc2cccc(Br)c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A07 compound treatment 563860.0 338000.0 0.7 618871.0 382000.0 0.83 1.078 0.9964 1644151 CBMicro_001605 Cc1ccc(C)c(COc2ccc3ccc(=O)oc3c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A08 compound treatment 595144.0 369000.0 0.76 633168.0 396000.0 0.86 1.1456 0.9982 1924117 CBMicro_001606 CCOC(=O)C(=CNc1ccccc1C(=O)O)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A09 compound treatment 578200.0 352000.0 0.73 627883.0 391000.0 0.85 1.1128 0.9971 1188901 CBMicro_001607 CC(C)c1cccc(C(C)C)c1NC(=O)c2cccs2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A10 compound treatment 571621.0 346000.0 0.71 617908.0 381000.0 0.83 1.0879 0.9974 1238842 CBMicro_001608 Cc1c(C)c2ccc(OCC(=O)O)cc2oc1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A11 compound treatment 582858.0 357000.0 0.74 638154.0 401000.0 0.87 1.1353 0.9966 1247823 CBMicro_001609 COc1ccc(cc1)c2cc(O)n3nc(c(C)c3n2)c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A12 compound treatment 579746.0 354000.0 0.73 629553.0 393000.0 0.85 1.1176 0.9971 1247187 CBMicro_001610 COc1ccccc1NC(=O)c2cc(Nc3ccccc3)nc4ccccc24 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A13 compound treatment 631234.0 405000.0 0.84 683190.0 446000.0 0.97 1.2748 0.9974 1707615 CBMicro_001611 Fc1ccc(cc1)C(=O)COc2ccc3c4CCCc4c(=O)oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A14 compound treatment 606522.0 381000.0 0.79 660250.0 424000.0 0.92 1.2036 0.997 1428762 CBMicro_001612 COc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(OC)ncn3)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A15 compound treatment 605620.0 380000.0 0.78 643245.0 407000.0 0.88 1.1763 0.9983 1924118 CBMicro_001613 COc1ccccc1N2CC=C(NC2=O)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A16 compound treatment 605214.0 379000.0 0.78 647792.0 411000.0 0.89 1.1827 0.998 1924119 CBMicro_001614 CN(C1=NC(=O)/C(=C\c2ccc(F)cc2)/S1)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A17 compound treatment 601949.0 376000.0 0.78 645501.0 409000.0 0.88 1.1744 0.9979 1924120 CBMicro_001615 COc1c(O)c(c2cc([nH]n2)c3ccccc3)c(OC)c4ccoc14 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A18 compound treatment 604709.0 379000.0 0.78 619551.0 383000.0 0.83 1.1387 0.9996 1924121 CBMicro_001616 O=C1NC(C2=C(Nc3ccccc3N=C2N1)c4ccccc4)c5cccc6ncccc56 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A19 compound treatment 592230.0 366000.0 0.76 629467.0 393000.0 0.85 1.1357 0.9983 1654792 CBMicro_001617 Cc1ccc(COc2ccc3c4CCCc4c(=O)oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A20 compound treatment 574216.0 348000.0 0.72 631262.0 395000.0 0.85 1.1121 0.9963 1924122 CBMicro_001618 Oc1ccccc1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A21 compound treatment 568818.0 343000.0 0.71 605415.0 369000.0 0.8 1.0647 0.9982 1176527 CBMicro_001619 CN(C)CCNC(=O)C(c1ccccc1)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A22 compound treatment 564103.0 338000.0 0.7 601109.0 364000.0 0.79 1.0512 0.9981 1924123 CBMicro_001620 Cc1cccc(NC(=O)CC2S/C(=N\N=C\c3cccs3)/N=C2O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A23 mock treatment 551830.0 326000.0 0.67 599790.0 363000.0 0.79 1.0313 0.997 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 A24 mock treatment 201925.0 -24100.0 -0.05 238932.0 2210.0 0.0 -0.0318 -0.636 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B01 mock treatment 10544.0 -215000.0 -0.44 14817.0 -222000.0 -0.48 -0.6541 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B02 mock treatment 10440.0 -216000.0 -0.44 14984.0 -222000.0 -0.48 -0.654 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B03 compound treatment 599194.0 373000.0 0.77 656245.0 420000.0 0.91 1.1868 0.9967 1924124 CBMicro_001621 COc1ccc(cc1)c2cc(O)n3nc(c(C)c3n2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B04 compound treatment 560998.0 335000.0 0.69 641834.0 405000.0 0.88 1.109 0.9931 1606171 CBMicro_001622 CCN(CC)CCN1C(Nc2ccccc2C1=O)c3ccc4OCOc4c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B05 compound treatment 571391.0 345000.0 0.71 678311.0 442000.0 0.96 1.18 0.9896 1924125 CBMicro_001623 Clc1ccccc1/C=N/N2C(=O)C3C(C4C=CC3C5CC54)C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B06 compound treatment 571746.0 346000.0 0.71 646954.0 410000.0 0.89 1.1325 0.9941 1198515 CBMicro_001624 CCCc1cc(O)n2nc(cc2n1)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B07 compound treatment 601349.0 375000.0 0.77 698474.0 462000.0 1.0 1.2546 0.9921 1924126 CBMicro_001625 Cc1ccc(cc1)c2noc(/C=C/c3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B08 compound treatment 592553.0 367000.0 0.76 671146.0 434000.0 0.94 1.1999 0.9942 1924127 CBMicro_001626 CCOC(=O)CCc1c(C)nc2cc(nn2c1O)c3cccc(F)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B09 compound treatment 601228.0 375000.0 0.77 697621.0 461000.0 1.0 1.2531 0.9922 1924128 CBMicro_001627 CC(C)/C(=N/N=C/1\SC(CC(=O)Nc2ccc(C)c(Cl)c2)C(=N1)O)/C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B10 compound treatment 606648.0 381000.0 0.79 697641.0 461000.0 1.0 1.261 0.993 1582038 CBMicro_001628 Ic1cccc(NC(=O)C(c2ccccc2)c3ccccc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B11 compound treatment 636622.0 411000.0 0.85 700889.0 464000.0 1.0 1.3098 0.9964 1924129 CBMicro_001629 COC(=O)C/1=C(C)N(C)C(=O)\C1=C/c2ccc(cc2)C(=O)OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B12 compound treatment 607871.0 382000.0 0.79 669493.0 433000.0 0.94 1.2198 0.9963 1924130 CBMicro_001630 CC(C)c1ccc(NC(=O)CC2SC(=N)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B13 compound treatment 617201.0 391000.0 0.81 706818.0 470000.0 1.02 1.2905 0.9934 1924131 CBMicro_001631 COC(=O)COc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B14 compound treatment 628013.0 402000.0 0.83 672624.0 436000.0 0.94 1.2539 0.998 1924132 CBMicro_001632 Cc1ccc(N2C(=O)C(=C(N3CCOCC3)C2=O)Cl)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B15 compound treatment 655510.0 430000.0 0.89 711398.0 475000.0 1.03 1.3534 0.9973 1347360 CBMicro_001633 C(Cc1ccccc1)c2nc(no2)c3cccnc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B16 compound treatment 628730.0 403000.0 0.83 693515.0 457000.0 0.99 1.287 0.9963 1924133 CBMicro_001634 CCOC(=O)CCc1c(C)nc2c(C)c(nn2c1O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B17 compound treatment 639965.0 414000.0 0.85 716782.0 480000.0 1.04 1.339 0.9953 1685228 CBMicro_001635 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)c4ccccc4)cc2)ncn1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B18 compound treatment 629578.0 404000.0 0.83 671249.0 435000.0 0.94 1.2541 0.9982 1924134 CBMicro_001636 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cc(Cl)ccc3[N+](=O)[O-])cc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B19 compound treatment 635431.0 409000.0 0.85 710465.0 474000.0 1.03 1.3227 0.9954 1148173 CBMicro_001637 Cc1cccc(OCc2nc(no2)c3ccccn3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B20 compound treatment 640526.0 415000.0 0.86 680987.0 444000.0 0.96 1.285 0.9983 1924135 CBMicro_001638 CC(N1C(=O)c2cccc3cccc(C1=O)c23)C(=O)N4CCOCC4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B21 compound treatment 610239.0 384000.0 0.79 684028.0 447000.0 0.97 1.2455 0.9951 1924136 CBMicro_001639 Clc1ccc(cc1)c2noc(CCc3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B22 compound treatment 581177.0 355000.0 0.73 658354.0 422000.0 0.91 1.1637 0.9941 1267290 CBMicro_001640 COc1cc(C(=O)Nc2c(C)cccc2C(C)C)c(Br)c(OC)c1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B23 mock treatment 599518.0 374000.0 0.77 672554.0 436000.0 0.94 1.2122 0.995 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 B24 mock treatment 218899.0 -7100.0 -0.01 257613.0 20900.0 0.05 0.0216 0.4546 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C01 mock treatment 10482.0 -216000.0 -0.44 13539.0 -223000.0 -0.48 -0.6562 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C02 mock treatment 10230.0 -216000.0 -0.45 14314.0 -222000.0 -0.48 -0.6553 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C03 compound treatment 576852.0 351000.0 0.72 664871.0 428000.0 0.93 1.1674 0.9926 1658144 CBMicro_001641 C=CCNC(=O)COc1ccc2ccccc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C04 compound treatment 588216.0 362000.0 0.75 640262.0 404000.0 0.87 1.1463 0.997 1924137 CBMicro_001642 COc1cc(C)cc2oc(=O)c3CCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C05 compound treatment 599406.0 373000.0 0.77 667627.0 431000.0 0.93 1.2045 0.9955 1924138 CBMicro_001643 CCOC(=O)/C(=C/Nc1ccccc1)/C(=O)Nc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C06 compound treatment 572353.0 346000.0 0.71 651092.0 414000.0 0.9 1.1397 0.9937 1924139 CBMicro_001644 CCc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C07 compound treatment 612959.0 387000.0 0.8 683340.0 447000.0 0.97 1.2484 0.9955 1729470 CBMicro_001645 CC(C)OC(=O)COc1ccc2c3CCCc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C08 compound treatment 615815.0 390000.0 0.8 670726.0 434000.0 0.94 1.2332 0.997 1206717 CBMicro_001646 COc1ccccc1N2COc3ccc4ccccc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C09 compound treatment 632272.0 406000.0 0.84 685905.0 449000.0 0.97 1.2805 0.9973 1329276 CBMicro_001647 CC(Oc1ccc2c(cc(=O)oc2c1C)c3ccccc3)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C10 compound treatment 635364.0 409000.0 0.85 662667.0 426000.0 0.92 1.2494 0.9991 1924140 CBMicro_001648 N/C(=N\OC(=O)COc1ccc2ccccc2c1)/c3ccccn3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C11 compound treatment 638298.0 412000.0 0.85 694258.0 458000.0 0.99 1.3021 0.9972 1924141 CBMicro_001649 CCNC(=O)CC1S/C(=N\N=C\c2ccco2)/N=C1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C12 compound treatment 632923.0 407000.0 0.84 720986.0 484000.0 1.05 1.3351 0.994 1924142 CBMicro_001650 CN1CCN(CC1)C2=C(Cl)C(=O)N(C2=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C13 compound treatment 681170.0 455000.0 0.94 698439.0 462000.0 1.0 1.371 0.9995 1720654 CBMicro_001651 Cc1ccc(C)c(COc2ccc3c4CCCc4c(=O)oc3c2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C14 compound treatment 624583.0 399000.0 0.82 688174.0 451000.0 0.98 1.2727 0.9963 1924143 CBMicro_001652 Cc1ccc(N2C(=O)C(=C(NCCO)C2=O)Cl)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C15 compound treatment 662098.0 436000.0 0.9 692271.0 456000.0 0.99 1.3338 0.999 1924144 CBMicro_001653 Oc1ccc(cc1)C2NC(=O)NC3=Nc4ccccc4SC(=C23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C16 compound treatment 648249.0 422000.0 0.87 686212.0 449000.0 0.97 1.3043 0.9985 1924145 CBMicro_001654 Clc1ccc(CN2C3C=CC=CC3C(=O)C2=O)cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C17 compound treatment 672816.0 447000.0 0.92 747552.0 511000.0 1.11 1.434 0.9959 1625312 CBMicro_001655 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)no1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C18 compound treatment 644212.0 418000.0 0.86 683346.0 447000.0 0.97 1.294 0.9984 1660390 CBMicro_001656 CCOc1ccc2cc(C(=O)c3ccccc3)c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C19 compound treatment 684849.0 459000.0 0.95 687209.0 450000.0 0.98 1.3592 0.9999 1924146 CBMicro_001657 CCc1cc(=O)oc2cc(C)cc(OC(C)C(=O)C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C20 compound treatment 641382.0 415000.0 0.86 666654.0 430000.0 0.93 1.2643 0.9992 1740290 CBMicro_001658 CCCOc1cccc(c1)C(=O)Nc2ccc(Br)cc2C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C21 compound treatment 695509.0 470000.0 0.97 708327.0 472000.0 1.02 1.4071 0.9997 1924147 CBMicro_001659 Clc1ccc(cc1)C(=O)NOC(=O)CCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C22 compound treatment 624926.0 399000.0 0.82 670177.0 433000.0 0.94 1.2457 0.9979 1924148 CBMicro_001660 CC/1=NN(C(=O)\C1=C\c2cccc(OC3CSC3)c2)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C23 mock treatment 632259.0 406000.0 0.84 660883.0 424000.0 0.92 1.2422 0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 C24 mock treatment 227444.0 1440.0 0.0 180877.0 -55800.0 -0.12 -0.0834 -0.6895 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D01 mock treatment 10335.0 -216000.0 -0.45 13309.0 -223000.0 -0.48 -0.6567 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D02 mock treatment 10063.0 -216000.0 -0.45 14723.0 -222000.0 -0.48 -0.655 -0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D03 compound treatment 558456.0 332000.0 0.69 646672.0 410000.0 0.89 1.1127 0.9919 1535581 CBMicro_001661 CC(C)CN(CC(C)C)c1ncnc2ccc(C)cc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D04 compound treatment 570408.0 344000.0 0.71 675770.0 439000.0 0.95 1.1747 0.9898 1291452 CBMicro_001662 CC(C)(C)OC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D05 compound treatment 586967.0 361000.0 0.75 692649.0 456000.0 0.99 1.2247 0.9904 1924149 CBMicro_001663 CCCCOc1ccc2c(=O)c(coc2c1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D06 compound treatment 594071.0 368000.0 0.76 671342.0 435000.0 0.94 1.2024 0.9944 1271813 CBMicro_001664 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)C3COc4ccccc4O3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D07 compound treatment 607568.0 382000.0 0.79 714823.0 478000.0 1.03 1.2887 0.9909 1626636 CBMicro_001665 Cc1ccc(C)c(COc2ccc3c4CCCc4c(=O)oc3c2C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D08 compound treatment 617130.0 391000.0 0.81 716452.0 480000.0 1.04 1.3051 0.9923 1924150 CBMicro_001666 CCOC(=O)C/1=C(C)N(C(=O)\C1=C/c2cccc(c2)[N+](=O)[O-])c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D09 compound treatment 627764.0 402000.0 0.83 709896.0 473000.0 1.02 1.3106 0.9945 1462861 CBMicro_001667 CC(C)(C)OC(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D10 compound treatment 632557.0 407000.0 0.84 704799.0 468000.0 1.01 1.3098 0.9956 1353454 CBMicro_001668 CCN(CC)CCN1C(Nc2ccccc2C1=O)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D11 compound treatment 634487.0 408000.0 0.84 706264.0 470000.0 1.02 1.3149 0.9957 1336782 CBMicro_001669 CCCc1cc2c(cc(=O)oc2cc1OCC(=O)O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D12 compound treatment 616322.0 390000.0 0.81 694428.0 458000.0 0.99 1.2702 0.9947 1640710 CBMicro_001670 Cc1cccc(NC(=O)COc2ccc3ccccc3c2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D13 compound treatment 660331.0 434000.0 0.9 734970.0 498000.0 1.08 1.3965 0.9958 1679732 CBMicro_001671 COc1c(Cl)ccc(Cl)c1C(=O)Nc2c(C)cccc2C(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D14 compound treatment 624963.0 399000.0 0.82 714796.0 478000.0 1.03 1.314 0.9936 1272479 CBMicro_001672 Clc1ccc(OCC(=O)N2CCN(CC2)c3ccccn3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D15 compound treatment 639723.0 414000.0 0.85 729400.0 493000.0 1.07 1.3579 0.9939 1924151 CBMicro_001673 Clc1ccccc1Cn2ncc(Cl)c(Cl)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D16 compound treatment 637720.0 412000.0 0.85 721951.0 485000.0 1.05 1.3436 0.9945 1924152 CBMicro_001674 CC(=O)Nc1ccc(cc1)C2NC(=O)NC3=Nc4ccccc4SC(=C23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D17 compound treatment 665918.0 440000.0 0.91 745854.0 509000.0 1.1 1.4213 0.9954 1244934 CBMicro_001675 Cc1ccc(COc2ccc3c(c2)oc(=O)c4ccccc43)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D18 compound treatment 681940.0 456000.0 0.94 717710.0 481000.0 1.04 1.4017 0.9987 1217283 CBMicro_001676 CN(Cc1ccccc1)Cc2c(C)nc3c(Cl)cccc3c2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D19 compound treatment 669108.0 443000.0 0.91 763739.0 527000.0 1.14 1.4534 0.994 1924153 CBMicro_001677 COC(=O)c1ccc(NC(=O)CCN2C(=O)c3cccc4cccc(C2=O)c34)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D20 compound treatment 631866.0 406000.0 0.84 749934.0 513000.0 1.11 1.3779 0.9903 1545949 CBMicro_001678 Oc1c2SCCc2nc3cc(nn13)c4cccc(F)c4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D21 compound treatment 652801.0 427000.0 0.88 770765.0 534000.0 1.16 1.4403 0.991 1596113 CBMicro_001679 Cc1ccc(COc2cc3oc(=O)c4CCCc4c3cc2Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D22 compound treatment 614920.0 389000.0 0.8 668839.0 432000.0 0.94 1.229 0.9971 1298585 CBMicro_001680 CCCN(CCC)C(=O)CC1(CC2CC3C1)CC(CC(=O)N(CCC)CCC)(C2)C3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D23 mock treatment 628029.0 402000.0 0.83 696569.0 460000.0 1.0 1.2906 0.9959 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 D24 mock treatment 196626.0 -29400.0 -0.06 303678.0 67000.0 0.14 0.0596 0.3794 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E01 mock treatment 10126.0 -216000.0 -0.45 13299.0 -223000.0 -0.48 -0.657 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E02 mock treatment 9853.0 -216000.0 -0.45 13173.0 -224000.0 -0.48 -0.6576 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E03 compound treatment 569472.0 343000.0 0.71 651795.0 415000.0 0.9 1.1366 0.9931 1924154 CBMicro_001681 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E04 compound treatment 569079.0 343000.0 0.71 652122.0 415000.0 0.9 1.1365 0.993 1924155 CBMicro_001682 FC(F)(F)COS(=O)(=O)CCN1C(=O)c2cccc3cccc(C1=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E05 compound treatment 586033.0 360000.0 0.74 656451.0 420000.0 0.91 1.1679 0.995 1924156 CBMicro_001683 C/C(=N\N=C\1/SC(CC(=O)Nc2cccc(C)c2C)C(=N1)O)/C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E06 compound treatment 594268.0 368000.0 0.76 639076.0 402000.0 0.87 1.1533 0.9977 1924157 CBMicro_001684 OC1=N/C(=N/N=C/c2ccccc2)/SC1CC(=O)Nc3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E07 compound treatment 626700.0 401000.0 0.83 652862.0 416000.0 0.9 1.2218 0.9991 1664742 CBMicro_001685 COc1ccc(cc1)c2noc(COc3ccc(C)cc3Br)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E08 compound treatment 612341.0 386000.0 0.8 669349.0 433000.0 0.94 1.2261 0.9968 1924158 CBMicro_001686 COC(=O)C/1=C(C)N(C(=O)\C1=C/c2cccc(OC)c2)c3ccccc3F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E09 compound treatment 636101.0 410000.0 0.85 675922.0 439000.0 0.95 1.2708 0.9983 1124344 CBMicro_001687 CCc1ccccc1NC(=O)CCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E10 compound treatment 603635.0 378000.0 0.78 669610.0 433000.0 0.94 1.2137 0.9958 1924159 CBMicro_001688 COc1ccc(NC(=O)COc2ccc3ccccc3c2)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E11 compound treatment 630084.0 404000.0 0.83 708281.0 472000.0 1.02 1.3115 0.995 1597235 CBMicro_001689 CCOc1ccc2c(=O)c(coc2c1)c3ccccc3OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E12 compound treatment 618708.0 393000.0 0.81 681030.0 444000.0 0.96 1.2532 0.9964 1924160 CBMicro_001690 CCOC(=O)C(=CNc1cccc(c1)C(=O)O)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E13 compound treatment 638243.0 412000.0 0.85 670307.0 434000.0 0.94 1.2653 0.9988 1924161 CBMicro_001691 Cc1cccc(c1)/C(=N/OC(=O)CCc2ccccc2)/N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E14 compound treatment 612135.0 386000.0 0.8 697133.0 460000.0 1.0 1.2683 0.9939 1447828 CBMicro_001692 COc1ccccc1c2coc3cc(OC(=O)c4cccc(Cl)c4)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E15 compound treatment 730868.0 505000.0 1.04 733413.0 497000.0 1.08 1.4971 0.9999 1340403 CBMicro_001693 CC1CCN(Cc2c(O)ccc3c4CCCc4c(=O)oc23)CC1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E16 compound treatment 666806.0 441000.0 0.91 703576.0 467000.0 1.01 1.3579 0.9986 1446249 CBMicro_001694 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3c(C)cc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E17 compound treatment 684315.0 458000.0 0.95 745710.0 509000.0 1.1 1.448 0.9971 1235313 CBMicro_001695 CCOC(=O)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E18 compound treatment 688140.0 462000.0 0.95 690479.0 454000.0 0.98 1.369 0.9999 1924162 CBMicro_001696 OC(=O)c1cccc(NC2=C(Cl)C(=O)N(C2=O)c3ccc(Cl)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E19 compound treatment 655764.0 430000.0 0.89 726347.0 490000.0 1.06 1.3767 0.9961 1924163 CBMicro_001697 [O-][N+](=O)c1ccccc1c2ccc(/C=C/C(=O)C3(CC4CC5CC(C4)C3)C5)o2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E20 compound treatment 638319.0 412000.0 0.85 683728.0 447000.0 0.97 1.286 0.998 1344488 CBMicro_001698 COc1cc(cc(OC)c1OC)C(=O)Nc2c(c3ccccc3)c4cc(Br)ccc4[nH]c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E21 compound treatment 657681.0 432000.0 0.89 696076.0 459000.0 0.99 1.3331 0.9985 1924164 CBMicro_001699 Brc1ccc2nc(NC(=O)/C=C/c3ccccc3)sc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E22 compound treatment 632782.0 407000.0 0.84 673676.0 437000.0 0.95 1.2625 0.9982 1707658 CBMicro_001700 CCOC(=O)c1c(NC(=O)C(OC(=O)C)c2ccccc2)sc3CCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E23 mock treatment 717795.0 492000.0 1.02 670913.0 434000.0 0.94 1.3824 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 E24 mock treatment 210156.0 -15800.0 -0.03 250660.0 13900.0 0.03 -0.0018 -0.0402 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F01 mock treatment 10178.0 -216000.0 -0.45 12942.0 -224000.0 -0.48 -0.6575 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F02 mock treatment 9895.0 -216000.0 -0.45 13843.0 -223000.0 -0.48 -0.6565 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F03 compound treatment 576876.0 351000.0 0.72 676614.0 440000.0 0.95 1.1854 0.9909 1564294 CBMicro_001701 COc1ccc(NC(=O)Cc2cccc3c(cccc23)S(=O)O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F04 compound treatment 553962.0 328000.0 0.68 681603.0 445000.0 0.96 1.1596 0.9851 1924165 CBMicro_001702 Cc1cccc(NC(=O)CC2S/C(=N\N=C\c3cccc(O)c3)/N=C2O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F05 compound treatment 585898.0 360000.0 0.74 752360.0 516000.0 1.12 1.3145 0.9804 1168414 CBMicro_001703 Cc1c(NC(=S)NC(=O)c2ccco2)cccc1c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F06 compound treatment 589841.0 364000.0 0.75 682490.0 446000.0 0.96 1.2133 0.9923 1924166 CBMicro_001704 COC(=O)CN1C(=O)/C(=C/c2cc(OC)ccc2OC)/SC1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F07 compound treatment 608542.0 383000.0 0.79 699953.0 463000.0 1.0 1.2673 0.993 1924167 CBMicro_001705 COc1ccccc1c2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F08 compound treatment 610698.0 385000.0 0.79 683340.0 447000.0 0.97 1.2451 0.9952 1924168 CBMicro_001706 COc1ccccc1c2c(oc3cc(O)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F09 compound treatment 617908.0 392000.0 0.81 705928.0 469000.0 1.02 1.2902 0.9937 1468954 CBMicro_001707 OC(=O)c1ccc(COc2ccc3ccc(=O)oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F10 compound treatment 590635.0 365000.0 0.75 680085.0 443000.0 0.96 1.2108 0.9928 1924169 CBMicro_001708 COc1cc(cc(OC)c1OC)c2noc(n2)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F11 compound treatment 645086.0 419000.0 0.87 718479.0 482000.0 1.04 1.349 0.9957 1924170 CBMicro_001709 CC(C)(CO)NCC(=O)NCCNc1ccc(cc1Cl)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F12 compound treatment 578762.0 353000.0 0.73 721342.0 485000.0 1.05 1.2566 0.9841 1924171 CBMicro_001710 COc1ccc(CC(=O)O/N=C(\N)/c2ccc(cc2)[N+](=O)[O-])cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F13 compound treatment 631502.0 406000.0 0.84 745975.0 509000.0 1.1 1.3713 0.9908 1230221 CBMicro_001711 CCOC(=O)c1cnc2c(ccc3ccccc32)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F14 compound treatment 632931.0 407000.0 0.84 701898.0 465000.0 1.01 1.3059 0.9959 1306347 CBMicro_001712 O=C(CC1SC(=O)NC1=O)Nc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F15 compound treatment 643726.0 418000.0 0.86 740827.0 504000.0 1.09 1.3813 0.9932 1924172 CBMicro_001713 C/C(=N\N=C\1/SC(CC(=O)Nc2ccc(cc2)C(=O)O)C(=N1)O)/c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F16 compound treatment 638729.0 413000.0 0.85 706963.0 470000.0 1.02 1.3221 0.9961 1924173 CBMicro_001714 CC(=O)Nc1ccccc1NC(=O)/C=C/c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F17 compound treatment 672770.0 447000.0 0.92 761894.0 525000.0 1.14 1.4559 0.9946 1924174 CBMicro_001715 Cc1cccc(NC(=O)CC2S/C(=N\N=C\3/CCCc4ccccc34)/N=C2O)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F18 compound treatment 629505.0 404000.0 0.83 700986.0 464000.0 1.0 1.2995 0.9957 1199086 CBMicro_001716 Cc1cc(OCC(=O)N)c2c3CCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F19 compound treatment 652823.0 427000.0 0.88 789790.0 553000.0 1.2 1.4695 0.9886 1410998 CBMicro_001717 Fc1cccc(Cl)c1COc2ccc3c(c2)oc(=O)c4ccccc43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F20 compound treatment 620842.0 395000.0 0.82 713390.0 477000.0 1.03 1.3059 0.9932 1200012 CBMicro_001718 OC(=O)COc1ccc2ccc(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F21 compound treatment 660530.0 435000.0 0.9 733529.0 497000.0 1.08 1.3946 0.9959 1924175 CBMicro_001719 COc1ccc(cc1)N2CN=C3SC(CO)(CO)C(=O)N3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F22 compound treatment 647914.0 422000.0 0.87 685788.0 449000.0 0.97 1.3031 0.9985 1685895 CBMicro_001720 O=CN1CCN(CC1)C(=O)COc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F23 mock treatment 619769.0 394000.0 0.81 691884.0 455000.0 0.99 1.2714 0.9954 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 F24 mock treatment 175756.0 -50200.0 -0.1 202406.0 -34300.0 -0.07 -0.1259 -0.9866 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G01 mock treatment 10544.0 -215000.0 -0.44 12764.0 -224000.0 -0.48 -0.6572 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G02 mock treatment 9864.0 -216000.0 -0.45 13026.0 -224000.0 -0.48 -0.6578 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G03 compound treatment 613872.0 388000.0 0.8 653486.0 417000.0 0.9 1.204 0.9982 1400268 CBMicro_001721 CCc1ccccc1NC(=O)COc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G04 compound treatment 580534.0 355000.0 0.73 654385.0 418000.0 0.9 1.1567 0.9945 1924176 CBMicro_001722 C/C(=N\N=C\1/SC(CC(=O)Nc2ccc(Cl)cc2)C(=N1)O)/C(C)(C)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G05 compound treatment 581825.0 356000.0 0.73 691483.0 455000.0 0.98 1.2154 0.9896 1924177 CBMicro_001723 Fc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G06 compound treatment 578658.0 353000.0 0.73 643478.0 407000.0 0.88 1.1373 0.9955 1515027 CBMicro_001724 CCc1cc(=O)oc2cc(C)cc(O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G07 compound treatment 622086.0 396000.0 0.82 692137.0 455000.0 0.99 1.2752 0.9957 1924178 CBMicro_001725 COC(=O)C1=C(C)N/C(=C\c2ccc(OCC(=O)NC(C)C)cc2)/C1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G08 compound treatment 596140.0 370000.0 0.76 684314.0 448000.0 0.97 1.2253 0.9931 1243799 CBMicro_001726 CCc1cc(=O)oc2cc(C)cc(OC(=O)C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G09 compound treatment 626049.0 400000.0 0.83 669321.0 433000.0 0.94 1.246 0.998 1338848 CBMicro_001727 CCOC(=O)c1cccc(Nc2ncnc3ccc(C)cc23)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G10 compound treatment 604368.0 378000.0 0.78 664949.0 428000.0 0.93 1.2077 0.9964 1924179 CBMicro_001728 CCOc1ccc(NC(=O)CC2S/C(=N\N=C\c3ccccc3OC)/N=C2O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G11 compound treatment 657842.0 432000.0 0.89 706886.0 470000.0 1.02 1.3499 0.9978 1924180 CBMicro_001729 CN1C(=NC(=O)C21COC(OC2)c3cccnc3)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G12 compound treatment 645535.0 420000.0 0.87 674575.0 438000.0 0.95 1.2825 0.999 1924181 CBMicro_001730 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(C2=O)c3cccc(Br)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G13 compound treatment 658530.0 433000.0 0.89 697606.0 461000.0 1.0 1.3367 0.9985 1924182 CBMicro_001731 N/C(=N\OC(=O)COc1ccc2ccccc2c1)/Cc3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G14 compound treatment 649628.0 424000.0 0.87 696905.0 460000.0 1.0 1.3227 0.9979 1653799 CBMicro_001732 O=C(N1c2ccccc2Sc3ccccc13)c4cc5ccccc5oc4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G15 compound treatment 675345.0 449000.0 0.93 713486.0 477000.0 1.03 1.3856 0.9986 1642879 CBMicro_001733 CN(C)C(=O)COc1ccc2ccc(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G16 compound treatment 635783.0 410000.0 0.85 708749.0 472000.0 1.02 1.3206 0.9956 1924183 CBMicro_001734 CC1(CC2CC(C)(C)C1)CN2S(=O)(=O)c3ccc(cc3)C(=O)Nc4ccc(Cl)c(c4)S(=O)(=O)N5CCOCC5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G17 compound treatment 688434.0 462000.0 0.95 724096.0 487000.0 1.05 1.4209 0.9988 1924184 CBMicro_001735 CCOc1ccc(NC(=O)CC2S/C(=N\N=C\c3ccc(O)c(OC)c3)/N=C2O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G18 compound treatment 603802.0 378000.0 0.78 689231.0 453000.0 0.98 1.244 0.9936 1924185 CBMicro_001736 Clc1ccc(cc1)c2noc(COc3ccc4ccccc4c3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G19 compound treatment 701750.0 476000.0 0.98 734143.0 497000.0 1.08 1.4557 0.9989 1924186 CBMicro_001737 OC(=O)c1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G20 compound treatment 640751.0 415000.0 0.86 693087.0 456000.0 0.99 1.3039 0.9975 1404212 CBMicro_001738 COc1ccccc1C(=O)N2CCN(CC2)S(=O)(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G21 compound treatment 688671.0 463000.0 0.96 706657.0 470000.0 1.02 1.3946 0.9995 1517859 CBMicro_001739 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(Br)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G22 compound treatment 640786.0 415000.0 0.86 674345.0 438000.0 0.95 1.2752 0.9987 1621421 CBMicro_001740 CC(C)c1cccc(C(C)C)c1NC(=O)CN2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G23 mock treatment 642283.0 416000.0 0.86 710382.0 474000.0 1.03 1.3326 0.9961 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 G24 mock treatment 237864.0 11900.0 0.02 303448.0 66700.0 0.14 0.1194 0.8154 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H01 mock treatment 9529.0 -216000.0 -0.45 12838.0 -224000.0 -0.48 -0.6586 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H02 mock treatment 9487.0 -217000.0 -0.45 13539.0 -223000.0 -0.48 -0.6576 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H03 compound treatment 539606.0 314000.0 0.65 651712.0 415000.0 0.9 1.0929 0.9871 1924187 CBMicro_001741 O=c1oc2ccccc2c3Oc4c(C(c5ccccc5)c31)c(=O)oc6ccccc46 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H04 compound treatment 545516.0 320000.0 0.66 657484.0 421000.0 0.91 1.1104 0.9875 1924188 CBMicro_001742 CCCCOc1cc(C)cc2oc(=O)c3CCCc3c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H05 compound treatment 552933.0 327000.0 0.67 685895.0 449000.0 0.97 1.1647 0.9841 1924189 CBMicro_001743 Cc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4c(F)c(F)c(F)c(F)c4F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H06 compound treatment 554500.0 328000.0 0.68 658628.0 422000.0 0.91 1.1252 0.9893 1924190 CBMicro_001744 CN(C1=NC(=O)/C(=C\c2ccc(Cl)cc2)/S1)c3ccc(O)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H07 compound treatment 586749.0 361000.0 0.74 670391.0 434000.0 0.94 1.1903 0.9934 1924191 CBMicro_001745 COc1ccccc1c2c(oc3cc(OCc4cccc(Cl)c4)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H08 compound treatment 573091.0 347000.0 0.72 655217.0 418000.0 0.91 1.1471 0.9933 1924192 CBMicro_001746 CC(=O)N1CC(CC1=O)c2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H09 compound treatment 605096.0 379000.0 0.78 702194.0 465000.0 1.01 1.2657 0.9922 1924193 CBMicro_001747 COc1ccc(cc1)C(=O)Oc2ccc3c(C)cc(=O)oc3c2C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H10 compound treatment 588822.0 363000.0 0.75 690617.0 454000.0 0.98 1.2243 0.991 1924194 CBMicro_001748 CC(=O)COc1ccc2c3CCCc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H11 compound treatment 587768.0 362000.0 0.75 691929.0 455000.0 0.99 1.2247 0.9907 1924195 CBMicro_001749 COc1ccc(CC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H12 compound treatment 595805.0 370000.0 0.76 678622.0 442000.0 0.96 1.2161 0.9938 1157129 CBMicro_001750 Cc1c(OCc2ccc(cc2)C(=O)O)ccc3c4CCCc4c(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H13 compound treatment 632462.0 406000.0 0.84 695886.0 459000.0 0.99 1.296 0.9965 1924196 CBMicro_001751 COc1ccc(CC(=O)O/N=C(\N)/c2ccc(Br)cc2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H14 compound treatment 576374.0 350000.0 0.72 707321.0 471000.0 1.02 1.2317 0.9859 1158167 CBMicro_001752 Cc1cccc(COc2ccc3c4ccccc4c(=O)oc3c2C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H15 compound treatment 631473.0 405000.0 0.84 720523.0 484000.0 1.05 1.3323 0.9938 1924197 CBMicro_001753 COc1ccc(cc1)c2noc(/C=C/c3ccccc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H16 compound treatment 600914.0 375000.0 0.77 684980.0 448000.0 0.97 1.2333 0.9937 1924198 CBMicro_001754 CC(Oc1ccc2ccc(=O)oc2c1)C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H17 compound treatment 728078.0 502000.0 1.04 721169.0 484000.0 1.05 1.4743 1.0 1368314 CBMicro_001755 O=C(COc1ccccc1)C(=C2Nc3ccccc3N2)C(=O)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H18 compound treatment 608776.0 383000.0 0.79 676927.0 440000.0 0.95 1.2325 0.9957 1219653 CBMicro_001756 COc1cc(NC(=O)COc2ccc3ccccc3c2)cc(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H19 compound treatment 682195.0 456000.0 0.94 717891.0 481000.0 1.04 1.4023 0.9987 1924199 CBMicro_001757 COc1ccc(C/C(=N/OC(=O)Cc2ccc(OC)c(OC)c2)/N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H20 compound treatment 609980.0 384000.0 0.79 680656.0 444000.0 0.96 1.2399 0.9954 1365018 CBMicro_001758 O=C(COc1ccc2ccccc2c1)Nc3ccncc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H21 compound treatment 623795.0 398000.0 0.82 717176.0 480000.0 1.04 1.316 0.9932 1924200 CBMicro_001759 CCOc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H22 compound treatment 622709.0 397000.0 0.82 657237.0 421000.0 0.91 1.2227 0.9986 1924201 CBMicro_001760 COc1cc(/C=N/N=C\2/SC(CC(=O)O)C(=O)N2c3ccc(O)cc3)ccc1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H23 mock treatment 616992.0 391000.0 0.81 653203.0 416000.0 0.9 1.2081 0.9985 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 H24 mock treatment 200354.0 -25600.0 -0.05 255309.0 18600.0 0.04 -0.009 -0.1351 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I01 mock treatment 10188.0 -216000.0 -0.45 12963.0 -224000.0 -0.48 -0.6575 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I02 mock treatment 10073.0 -216000.0 -0.45 12984.0 -224000.0 -0.48 -0.6576 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I03 compound treatment 581794.0 356000.0 0.73 650903.0 414000.0 0.9 1.1532 0.9951 1252474 CBMicro_001761 CC(Oc1cc(C)cc2oc(=O)c3CCCc3c12)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I04 compound treatment 558572.0 333000.0 0.69 686838.0 450000.0 0.97 1.1743 0.9853 1924202 CBMicro_001762 COc1cc(ccc1NC(=O)c2ccc(cc2)S(=O)(=O)N3CC(C)OC(C)C3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I05 compound treatment 596830.0 371000.0 0.77 682234.0 446000.0 0.96 1.2231 0.9935 1185781 CBMicro_001763 CC1=C(C)CC2C(C1)C(=O)N(C2=O)c3cccc(C)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I06 compound treatment 557295.0 331000.0 0.68 651831.0 415000.0 0.9 1.1189 0.9909 1562162 CBMicro_001764 Clc1ccc(NC(=O)COc2ccc3ccccc3c2)nc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I07 compound treatment 604645.0 379000.0 0.78 702982.0 466000.0 1.01 1.2663 0.992 1924203 CBMicro_001765 Cc1cc(OCc2ccccc2)c3c4CCCc4c(=O)oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I08 compound treatment 604013.0 378000.0 0.78 670731.0 434000.0 0.94 1.216 0.9958 1924204 CBMicro_001766 Cc1cc(OCc2ccc(Cl)cc2)c3c4CCCc4c(=O)oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I09 compound treatment 617679.0 392000.0 0.81 646521.0 410000.0 0.89 1.1989 0.9989 1924205 CBMicro_001767 Cc1ccc(cc1C)c2nn(c3cc(ccc3[N+](=O)[O-])N4CCN(CCO)CC4)c(=O)c5ccccc25 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I10 compound treatment 597698.0 372000.0 0.77 664547.0 428000.0 0.93 1.1973 0.9956 1924206 CBMicro_001768 [O-][N+](=O)c1ccccc1/C=C(/C(=O)c2ccccc2)\c3nc4ccccc4[nH]3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I11 compound treatment 615677.0 390000.0 0.8 686754.0 450000.0 0.97 1.2576 0.9955 1133880 CBMicro_001769 Cc1ccc(OCC(=O)Oc2ccc(cc2C)C(=O)c3ccccc3)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I12 compound treatment 607228.0 381000.0 0.79 680934.0 444000.0 0.96 1.2363 0.9951 1365918 CBMicro_001770 COc1ccc(cc1)c2noc(COc3ccc(Cl)cc3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I13 compound treatment 625984.0 400000.0 0.83 694879.0 458000.0 0.99 1.285 0.9959 1508336 CBMicro_001771 COc1cc(cc(OC)c1OC)C2Nc3ccccc3C(=O)N2c4ccc(F)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I14 compound treatment 654514.0 429000.0 0.88 708769.0 472000.0 1.02 1.3479 0.9974 1740674 CBMicro_001772 Cc1ccc(cc1)c2noc(COc3ccc4ccccc4c3)n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I15 compound treatment 677046.0 451000.0 0.93 692321.0 456000.0 0.99 1.3557 0.9996 1924207 CBMicro_001773 CCOc1ccc(NC(=O)c2cccc(Oc3ccccc3)c2)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I16 compound treatment 649825.0 424000.0 0.87 696453.0 460000.0 1.0 1.3223 0.9979 1924208 CBMicro_001774 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc(cs3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I17 compound treatment 698575.0 473000.0 0.98 801292.0 565000.0 1.22 1.5539 0.9938 1143316 CBMicro_001775 Clc1ccc(cc1)C2Nc3ccccc3C(=O)N2Cc4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I18 compound treatment 647210.0 421000.0 0.87 688729.0 452000.0 0.98 1.3066 0.9983 1416656 CBMicro_001776 CC1CCc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45)sc2C1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I19 compound treatment 640025.0 414000.0 0.85 720969.0 484000.0 1.05 1.3455 0.9949 1526787 CBMicro_001777 CC1(C)CC(CC(C)(C)N1)NC(=O)CCc2ccccc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I20 compound treatment 634784.0 409000.0 0.84 680987.0 444000.0 0.96 1.2766 0.9979 1783109 CBMicro_001778 OC(=O)c1cc(O)ccc1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I21 compound treatment 651443.0 425000.0 0.88 679903.0 443000.0 0.96 1.2993 0.999 1924209 CBMicro_001779 Cc1ccc(N2C(=O)C(=C(Nc3ccc(F)cc3)C2=O)Cl)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I22 compound treatment 659222.0 433000.0 0.89 687532.0 451000.0 0.98 1.3223 0.9991 1924210 CBMicro_001780 Cc1ccc(cc1)C(c2c(O)c3ccccc3oc2=O)c4c(O)c5ccccc5oc4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I23 mock treatment 656884.0 431000.0 0.89 680152.0 443000.0 0.96 1.3076 0.9993 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 I24 mock treatment 230376.0 4380.0 0.01 230324.0 -6390.0 -0.01 -0.0034 -0.2057 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J01 mock treatment 10471.0 -216000.0 -0.44 12555.0 -224000.0 -0.49 -0.6577 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J02 mock treatment 9529.0 -216000.0 -0.45 12901.0 -224000.0 -0.48 -0.6585 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J03 compound treatment 544842.0 319000.0 0.66 667290.0 431000.0 0.93 1.1244 0.9855 1924211 CBMicro_001781 C/C(=N\N=C\1/SC(CC(=O)Nc2ccccc2C(F)(F)F)C(=N1)O)/c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J04 compound treatment 544074.0 318000.0 0.66 640386.0 404000.0 0.87 1.0821 0.9901 1924212 CBMicro_001782 OC(=O)CC1S/C(=N/N=C\2/C(=O)Nc3ccccc23)/N(C1=O)c4ccc(O)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J05 compound treatment 572163.0 346000.0 0.71 676590.0 440000.0 0.95 1.1785 0.99 1262559 CBMicro_001783 CCOC(=O)C1(NC(=O)CC1c2ccccc2)C(=O)O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J06 compound treatment 566418.0 340000.0 0.7 685451.0 449000.0 0.97 1.1837 0.9874 1924213 CBMicro_001784 NS(=O)(=O)c1ccc(NC2=NC(=O)CS2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J07 compound treatment 749893.0 524000.0 1.08 671548.0 435000.0 0.94 1.4302 0.9976 1924214 CBMicro_001785 COc1ccc(CC(=O)ONC(=O)c2ccc(Cl)cc2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J08 compound treatment 585574.0 360000.0 0.74 681155.0 444000.0 0.96 1.2051 0.9918 1636655 CBMicro_001786 Cc1c(OCC(=O)N)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J09 compound treatment 594496.0 368000.0 0.76 655363.0 419000.0 0.91 1.1786 0.9962 1924215 CBMicro_001787 COc1ccc(CC(=O)O/N=C(\N)/Cc2ccc(Cl)cc2Cl)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J10 compound treatment 585859.0 360000.0 0.74 671337.0 435000.0 0.94 1.1904 0.9932 1924216 CBMicro_001788 Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J11 compound treatment 616153.0 390000.0 0.81 677907.0 441000.0 0.95 1.2447 0.9964 1924217 CBMicro_001789 Cc1cc(OCC(=O)c2ccc(Cl)cc2)c3c4CCCc4c(=O)oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J12 compound treatment 594364.0 368000.0 0.76 684096.0 447000.0 0.97 1.2224 0.9928 1236972 CBMicro_001790 CCOC(=O)C1(C(CC(O)N1C(=O)C)c2ccccc2)C(=O)OCC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J13 compound treatment 625766.0 400000.0 0.83 715045.0 478000.0 1.04 1.3156 0.9937 1610943 CBMicro_001791 CC(C)(C)OC(=O)COc1cc2oc(=O)cc(c3ccccc3)c2cc1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J14 compound treatment 630693.0 405000.0 0.84 686114.0 449000.0 0.97 1.2785 0.9971 1163323 CBMicro_001792 CCOc1ccc(NC(=O)C(NS(=O)(=O)c2ccc(C)cc2)C(C)C)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J15 compound treatment 640492.0 414000.0 0.86 702700.0 466000.0 1.01 1.3182 0.9967 1924218 CBMicro_001793 Cc1n[nH]c(=S)n(/N=C/c2cc(Cl)ccc2Cl)c1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J16 compound treatment 616310.0 390000.0 0.81 702905.0 466000.0 1.01 1.2832 0.9938 1924219 CBMicro_001794 Cc1ccc(OCc2nc(no2)c3ccc(cc3)[N+](=O)[O-])c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J17 compound treatment 608745.0 383000.0 0.79 692773.0 456000.0 0.99 1.2567 0.9939 1924220 CBMicro_001795 COc1ccc(NC2=C(Cl)C(=O)N(C2=O)c3ccccc3Cl)c(OC)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J18 compound treatment 642517.0 417000.0 0.86 707730.0 471000.0 1.02 1.3288 0.9964 1148904 CBMicro_001796 Clc1cccc(c1)C(=O)Nc2ccccc2c3nc4ccccc4s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J19 compound treatment 625916.0 400000.0 0.83 708353.0 472000.0 1.02 1.3056 0.9945 1439296 CBMicro_001797 CC(Oc1ccc2ccc(=O)oc2c1)C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J20 compound treatment 613696.0 388000.0 0.8 687684.0 451000.0 0.98 1.2561 0.9951 1924221 CBMicro_001798 Oc1c(C(c2ccccc2F)c3c(O)c4ccccc4oc3=O)c(=O)oc5ccccc15 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J21 compound treatment 652262.0 426000.0 0.88 713628.0 477000.0 1.03 1.3521 0.9968 1623872 CBMicro_001799 Cc1ccc2nc(C)c(CN3CCCC3)c(O)c2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J22 compound treatment 638737.0 413000.0 0.85 679692.0 443000.0 0.96 1.2804 0.9983 1924222 CBMicro_001800 CC(=O)Nc1cccc(c1)/C(=N/N=C/2\SC(CC(=O)Nc3ccc(cc3)C(=O)O)C(=N2)O)/C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J23 mock treatment 646430.0 420000.0 0.87 670582.0 434000.0 0.94 1.2777 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 J24 mock treatment 264985.0 39000.0 0.08 248754.0 12000.0 0.03 0.0753 0.8905 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K01 mock treatment 10262.0 -216000.0 -0.45 12157.0 -225000.0 -0.49 -0.6586 -0.999 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K02 mock treatment 9612.0 -216000.0 -0.45 12723.0 -224000.0 -0.48 -0.6587 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K03 compound treatment 595997.0 370000.0 0.76 654341.0 418000.0 0.9 1.1792 0.9965 1389259 CBMicro_001801 CCCCN(CC)Cc1c(C)nc2ccc(C)cc2c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K04 compound treatment 557914.0 332000.0 0.69 634395.0 398000.0 0.86 1.0931 0.9936 1924223 CBMicro_001802 COc1ccccc1c2c(oc3c(CN(C)C)c(O)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K05 compound treatment 574517.0 349000.0 0.72 646534.0 410000.0 0.89 1.1359 0.9946 1924224 CBMicro_001803 CCc1cc(=O)oc2cc(OC/C=C/c3ccccc3)ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K06 compound treatment 565714.0 340000.0 0.7 661431.0 425000.0 0.92 1.1459 0.9911 1924225 CBMicro_001804 OC1=N/C(=N/N=C/c2cccs2)/SC1CC(=O)Nc3ccc(Cl)cc3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K07 compound treatment 616496.0 390000.0 0.81 682668.0 446000.0 0.97 1.2525 0.996 1684294 CBMicro_001805 COc1ccc(cc1)N2CCSC2C(=O)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K08 compound treatment 591120.0 365000.0 0.75 643456.0 407000.0 0.88 1.1555 0.997 1203580 CBMicro_001806 COc1cc(ccc1O)C2Nc3ccccc3C(=O)N2c4ccc(C)cc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K09 compound treatment 608284.0 382000.0 0.79 676534.0 440000.0 0.95 1.2311 0.9957 1547576 CBMicro_001807 CCCc1cc(=O)oc2cc(C)cc(O)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K10 compound treatment 580115.0 354000.0 0.73 639228.0 403000.0 0.87 1.1329 0.9962 1343535 CBMicro_001808 C=Cc1ccc(COc2ccc3c4CCCc4c(=O)oc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K11 compound treatment 613934.0 388000.0 0.8 681026.0 444000.0 0.96 1.2463 0.9959 1268565 CBMicro_001809 Oc1ccc2c3CCCc3c(=O)oc2c1O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K12 compound treatment 601581.0 376000.0 0.78 646326.0 410000.0 0.89 1.1751 0.9978 1356434 CBMicro_001810 CC1CCCC(C)N1C(=O)COc2ccc3ccccc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K13 compound treatment 616803.0 391000.0 0.81 723830.0 487000.0 1.05 1.316 0.9913 1924226 CBMicro_001811 CN(CCS(=O)(=O)OCC(F)(F)F)c1ccc(C=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K14 compound treatment 607152.0 381000.0 0.79 643117.0 406000.0 0.88 1.1783 0.9985 1924227 CBMicro_001812 COc1ccc(cc1Br)S(=O)(=O)Nc2cc(C)ccc2OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K15 compound treatment 744668.0 519000.0 1.07 711796.0 475000.0 1.03 1.4842 0.9998 1197081 CBMicro_001813 CCOC(=O)C(C)Oc1ccc2c3ccccc3c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K16 compound treatment 640811.0 415000.0 0.86 680051.0 443000.0 0.96 1.284 0.9984 1924228 CBMicro_001814 Cc1ccc(cc1)C(=O)N2CCN(CC2)c3ccc(Cl)cc3[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K17 compound treatment 672779.0 447000.0 0.92 708983.0 472000.0 1.02 1.3749 0.9987 1530864 CBMicro_001815 Cc1cccc(OCC(=O)Nc2ccc(OCc3ccccc3)cc2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K18 compound treatment 641177.0 415000.0 0.86 702721.0 466000.0 1.01 1.3192 0.9967 1924229 CBMicro_001816 Cc1ccc(OCc2nc(no2)c3ccc(Cl)cc3)c(Br)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K19 compound treatment 668404.0 442000.0 0.91 711141.0 474000.0 1.03 1.3719 0.9983 1198519 CBMicro_001817 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(Oc4ccccc4)c3)cc2)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K20 compound treatment 645720.0 420000.0 0.87 676320.0 440000.0 0.95 1.2854 0.9989 1418235 CBMicro_001818 OC(=O)c1ccc(cc1)n2ncc(Cl)c(Cl)c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K21 compound treatment 651971.0 426000.0 0.88 700930.0 464000.0 1.0 1.3322 0.9978 1785804 CBMicro_001819 CCc1c(C)nn(c1O)c2nc(cs2)c3cccc(c3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K22 compound treatment 648062.0 422000.0 0.87 669470.0 433000.0 0.94 1.2784 0.9993 1603166 CBMicro_001820 Cc1c(OCC(=O)c2ccc(Cl)cc2)ccc3c4CCCc4c(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K23 mock treatment 643808.0 418000.0 0.86 685237.0 449000.0 0.97 1.2963 0.9983 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 K24 mock treatment 207611.0 -18400.0 -0.04 231633.0 -5080.0 -0.01 -0.0346 -0.876 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L01 mock treatment 9969.0 -216000.0 -0.45 11916.0 -225000.0 -0.49 -0.6594 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L02 mock treatment 9351.0 -217000.0 -0.45 12681.0 -224000.0 -0.48 -0.6591 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L03 compound treatment 609457.0 383000.0 0.79 770692.0 534000.0 1.16 1.3769 0.983 1924230 CBMicro_001821 FC(F)(F)c1cccc(c1)C(=O)NC2=Nc3cccc4cccc2c34 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L04 compound treatment 543422.0 317000.0 0.66 650706.0 414000.0 0.9 1.0969 0.9882 1924231 CBMicro_001822 ClC(Cl)C(=O)Nc1nc(cs1)c2cc(Cl)ccc2Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L05 compound treatment 569079.0 343000.0 0.71 663847.0 427000.0 0.92 1.1545 0.9913 1924232 CBMicro_001823 OC1=N/C(=N/N=C/c2cccc(O)c2)/SC1CC(=O)Nc3ccccc3C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L06 compound treatment 575291.0 349000.0 0.72 647936.0 411000.0 0.89 1.1392 0.9945 1924233 CBMicro_001824 Cc1nc2ccccc2c(=O)n1N3C(=O)CCCC3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L07 compound treatment 582429.0 356000.0 0.74 650017.0 413000.0 0.89 1.1528 0.9953 1924234 CBMicro_001825 Fc1cccc(c1)C2c3c(Oc4c2c(=O)oc5ccccc45)c6ccccc6oc3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L08 compound treatment 565015.0 339000.0 0.7 647940.0 411000.0 0.89 1.1242 0.9929 1924235 CBMicro_001826 C=CCC1S/C(=N\N=C\c2ccccc2)/NC1=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L09 compound treatment 593388.0 367000.0 0.76 679726.0 443000.0 0.96 1.2143 0.9933 1924236 CBMicro_001827 COC(=O)C/1=C(C)N(CC(C)C)C(=O)\C1=C/c2cccc(OC)c2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L10 compound treatment 581352.0 355000.0 0.73 644492.0 408000.0 0.88 1.1428 0.9958 1243108 CBMicro_001828 Clc1ccc(NC(=O)COc2ccc3ccccc3c2)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L11 compound treatment 600092.0 374000.0 0.77 671758.0 435000.0 0.94 1.2119 0.9952 1924237 CBMicro_001829 C/C(=N\N=C\1/SC(CC(=O)Nc2ccc(cc2)[N+](=O)[O-])C(=N1)O)/c3ccc(F)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L12 compound treatment 583970.0 358000.0 0.74 669684.0 433000.0 0.94 1.1852 0.9931 1640745 CBMicro_001830 OC1(CC(=O)c2cccc3ccccc23)C(=O)Nc4ccccc41 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L13 compound treatment 648397.0 422000.0 0.87 684300.0 448000.0 0.97 1.3016 0.9986 1924238 CBMicro_001831 CC(=O)COc1ccc2c(C)c(C)c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L14 compound treatment 616964.0 391000.0 0.81 693689.0 457000.0 0.99 1.2701 0.9949 1392685 CBMicro_001832 COC(=O)COc1ccc2ccc(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L15 compound treatment 638146.0 412000.0 0.85 692952.0 456000.0 0.99 1.2998 0.9972 1321177 CBMicro_001833 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)COc3ccc(Cl)cc3C)cc2)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L16 compound treatment 617493.0 391000.0 0.81 683021.0 446000.0 0.97 1.2545 0.9961 1924239 CBMicro_001834 Cc1cccc(c1)C(=O)Nc2nc3ccc(Br)cc3s2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L17 compound treatment 620782.0 395000.0 0.81 725397.0 489000.0 1.06 1.3242 0.9917 1924240 CBMicro_001835 Clc1ccc(Cl)c(Cn2ncc(Cl)c(Cl)c2=O)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L18 compound treatment 611732.0 386000.0 0.8 662753.0 426000.0 0.92 1.2151 0.9973 1924241 CBMicro_001836 Cc1ccc(N2C(=O)C(=C(Nc3ccccc3F)C2=O)Cl)c(C)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L19 compound treatment 648863.0 423000.0 0.87 673808.0 437000.0 0.95 1.2862 0.9992 1924242 CBMicro_001837 N/C(=N\OC(=O)COc1ccc2ccccc2c1)/c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L20 compound treatment 637817.0 412000.0 0.85 671426.0 435000.0 0.94 1.2664 0.9987 1478049 CBMicro_001838 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2)nc(OC)n1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L21 compound treatment 638209.0 412000.0 0.85 678593.0 442000.0 0.96 1.278 0.9983 1502005 CBMicro_001839 Clc1cccc(Cc2cnc(NC(=O)C3CC3)s2)c1Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L22 compound treatment 627703.0 402000.0 0.83 653920.0 417000.0 0.9 1.2249 0.9991 1691327 CBMicro_001840 Fc1ccc(cc1)C(=O)Nc2nc(CC3(CC4CC5CC(C4)C3)C5)cs2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L23 mock treatment 619376.0 393000.0 0.81 663044.0 426000.0 0.92 1.2267 0.998 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 L24 mock treatment 242691.0 16700.0 0.03 210396.0 -26300.0 -0.06 -0.0159 -0.2391 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M01 mock treatment 9989.0 -216000.0 -0.45 12545.0 -224000.0 -0.49 -0.6584 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M02 mock treatment 9550.0 -216000.0 -0.45 12084.0 -225000.0 -0.49 -0.6597 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M03 compound treatment 571208.0 345000.0 0.71 681863.0 445000.0 0.96 1.1852 0.989 1924243 CBMicro_001841 CCOC(=O)c1c(NC(=O)/C=C/c2cccs2)sc3CCCc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M04 compound treatment 551464.0 325000.0 0.67 624882.0 388000.0 0.84 1.0691 0.9939 1700877 CBMicro_001842 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4ccncc4)c(=O)n23)C(=O)Nc5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M05 compound treatment 559667.0 334000.0 0.69 657014.0 420000.0 0.91 1.1303 0.9906 1924244 CBMicro_001843 COc1ccc(CC(=O)O/N=C(\N)/c2cccnc2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M06 compound treatment 573418.0 347000.0 0.72 658705.0 422000.0 0.91 1.153 0.9928 1406337 CBMicro_001844 COc1ccccc1c2coc3c(CN4CCC(C)CC4)c(O)ccc3c2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M07 compound treatment 612726.0 387000.0 0.8 658821.0 422000.0 0.91 1.2105 0.9977 1924245 CBMicro_001845 Cc1ccc(CC2CC2(Cl)Cl)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M08 compound treatment 579766.0 354000.0 0.73 655897.0 419000.0 0.91 1.1579 0.9942 1924246 CBMicro_001846 COc1ccc(cc1OC)C2NC(=O)NC(=C2c3ccc4ccccc4n3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M09 compound treatment 567503.0 342000.0 0.7 698853.0 462000.0 1.0 1.2058 0.9853 1924247 CBMicro_001847 OC1=N/C(=N/N=C/c2cccs2)/SC1CC(=O)Nc3ccc(Cl)c(Cl)c3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M10 compound treatment 573431.0 347000.0 0.72 653823.0 417000.0 0.9 1.1455 0.9935 1924248 CBMicro_001848 COc1cccc(c1)N2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M11 compound treatment 616948.0 391000.0 0.81 685501.0 449000.0 0.97 1.2575 0.9958 1924249 CBMicro_001849 COC(=O)Oc1ccc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M12 compound treatment 583553.0 358000.0 0.74 654261.0 418000.0 0.9 1.1609 0.9949 1661759 CBMicro_001850 CC(C)OC(=O)COc1ccc2c(c1)oc(=O)c3ccccc32 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M13 compound treatment 592681.0 367000.0 0.76 704872.0 468000.0 1.01 1.2517 0.9897 1173627 CBMicro_001851 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)c4cc5ccccc5oc4=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M14 compound treatment 650215.0 424000.0 0.88 671735.0 435000.0 0.94 1.285 0.9993 1924250 CBMicro_001852 COc1ccc(cc1OC)C2OCC3(CO2)SC4=NCN(C)CN4C3=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M15 compound treatment 634237.0 408000.0 0.84 704856.0 468000.0 1.01 1.3124 0.9958 1303619 CBMicro_001853 Cc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45)nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M16 compound treatment 616594.0 391000.0 0.81 697409.0 461000.0 1.0 1.2752 0.9944 1299158 CBMicro_001854 Cc1c(O)ccc2c3CCCc3c(=O)oc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M17 compound treatment 651035.0 425000.0 0.88 690948.0 454000.0 0.98 1.3156 0.9984 1312130 CBMicro_001855 CCCN1C(Nc2ccccc2C1=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M18 compound treatment 641062.0 415000.0 0.86 669423.0 433000.0 0.94 1.2681 0.999 1413186 CBMicro_001856 Fc1ccc(cc1)c2cc(NC(=O)c3ccc(Br)cc3)[nH]n2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M19 compound treatment 657726.0 432000.0 0.89 705965.0 469000.0 1.02 1.3483 0.9979 1924251 CBMicro_001857 CCCc1cc(=O)oc2cc(C)cc(OCC(=O)C)c12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M20 compound treatment 642698.0 417000.0 0.86 658534.0 422000.0 0.91 1.2538 0.9996 1557539 CBMicro_001858 COc1cccc2sc(NC(=O)c3cccc(Cl)c3)nc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M21 compound treatment 684334.0 458000.0 0.95 690399.0 454000.0 0.98 1.3634 0.9998 1924252 CBMicro_001859 O=C1NC(C(=C(N1)c2ccccc2)c3ccc4ccccc4n3)c5ccncc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M22 compound treatment 636026.0 410000.0 0.85 676178.0 439000.0 0.95 1.2711 0.9983 1924253 CBMicro_001860 COc1ccc(OC)c(c1)C2NC(=O)NC3=Nc4ccccc4NC(=C23)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M23 mock treatment 657390.0 431000.0 0.89 691582.0 455000.0 0.98 1.3258 0.9987 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 M24 mock treatment 374990.0 149000.0 0.31 396719.0 160000.0 0.35 0.4624 0.9982 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N01 mock treatment 10230.0 -216000.0 -0.45 12607.0 -224000.0 -0.49 -0.6579 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N02 mock treatment 13079.0 -213000.0 -0.44 12712.0 -224000.0 -0.48 -0.6536 -0.9988 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N03 compound treatment 547056.0 321000.0 0.66 621230.0 385000.0 0.83 1.0571 0.9936 1924254 CBMicro_001861 COc1ccc(cc1OC)c2cc(n[nH]2)c3ccccc3O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N04 compound treatment 519955.0 294000.0 0.61 626928.0 390000.0 0.84 1.0263 0.9868 1147839 CBMicro_001862 CCCc1cc2c(cc(=O)oc2cc1OC(C)C(=O)OC)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N05 compound treatment 556964.0 331000.0 0.68 666300.0 430000.0 0.93 1.1406 0.9885 1924255 CBMicro_001863 CCc1cc(=O)oc2cc(OC(=O)C)ccc12 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N06 compound treatment 543939.0 318000.0 0.66 638141.0 401000.0 0.87 1.0784 0.9904 1154822 CBMicro_001864 COc1ccc(cc1OC)C(=O)CC(=O)c2ccccc2O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N07 compound treatment 561733.0 336000.0 0.69 625096.0 388000.0 0.84 1.0845 0.9954 1203196 CBMicro_001865 COc1ccc(NC(=O)c2cccc(Oc3ccccc3)c2)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N08 compound treatment 565157.0 339000.0 0.7 653588.0 417000.0 0.9 1.1331 0.9921 1924256 CBMicro_001866 COc1ccc(Oc2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N09 compound treatment 583182.0 357000.0 0.74 652466.0 416000.0 0.9 1.1577 0.9951 1646363 CBMicro_001867 Clc1ccccc1COc2ccc3ccc(=O)oc3c2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N10 compound treatment 562758.0 337000.0 0.7 622697.0 386000.0 0.84 1.0823 0.9958 1924257 CBMicro_001868 COc1ccc2c(C)c(C)c(=O)oc2c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N11 compound treatment 578352.0 352000.0 0.73 645824.0 409000.0 0.89 1.1404 0.9952 1924258 CBMicro_001869 Oc1cc(nc2cc(nn12)c3cccc(F)c3)c4ccc(cc4)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N12 compound treatment 579697.0 354000.0 0.73 626180.0 389000.0 0.84 1.1123 0.9974 1924259 CBMicro_001870 COc1ccc(CCNc2cc(ccc2[N+](=O)[O-])N3CCN(CC3)C(=O)c4ccc(Br)cc4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N13 compound treatment 577384.0 351000.0 0.73 667770.0 431000.0 0.93 1.1726 0.9923 1924260 CBMicro_001871 N/C(=N\OC(=O)COc1ccc2ccccc2c1)/c3ccc(cc3)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N14 compound treatment 602422.0 376000.0 0.78 638471.0 402000.0 0.87 1.1643 0.9984 1285583 CBMicro_001872 COC(=O)c1nc(NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)n[nH]1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N15 compound treatment 597806.0 372000.0 0.77 842648.0 606000.0 1.31 1.4701 0.9674 1924261 CBMicro_001873 C(Sc1nc2ccccc2s1)c3nnc(Nc4ccccc4)s3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N16 compound treatment 607182.0 381000.0 0.79 661141.0 424000.0 0.92 1.206 0.997 1924262 CBMicro_001874 Cc1cccc(OCc2nc(no2)c3ccc(Cl)cc3)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N17 compound treatment 625834.0 400000.0 0.83 676985.0 440000.0 0.95 1.2574 0.9974 1924263 CBMicro_001875 Cc1cc(Cl)ccc1OC(=O)/C=C/c2cccc(c2)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N18 compound treatment 542725.0 317000.0 0.65 559914.0 323000.0 0.7 0.957 0.9994 1924264 CBMicro_001876 COc1ccccc1NC2=C(Cl)C(=O)N(C2=O)c3ccc(C)cc3C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N19 compound treatment 631837.0 406000.0 0.84 683490.0 447000.0 0.97 1.2762 0.9974 1924265 CBMicro_001877 C/C(=N\N=C\1/SC(CC(=O)Nc2ccc(Cl)cc2Cl)C(=N1)O)/c3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N20 compound treatment 638800.0 413000.0 0.85 719770.0 483000.0 1.05 1.3418 0.9948 1313999 CBMicro_001878 OC(=O)c1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N21 compound treatment 646564.0 421000.0 0.87 666945.0 430000.0 0.93 1.2723 0.9994 1924266 CBMicro_001879 [O-][N+](=O)c1cccc(c1)C2NC(=O)NC(=C2c3ccc4ccccc4n3)c5ccccc5 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N22 compound treatment 600133.0 374000.0 0.77 633006.0 396000.0 0.86 1.1526 0.9986 1924267 CBMicro_001880 CCOc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)c(c1)[N+](=O)[O-] 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N23 mock treatment 626769.0 401000.0 0.83 651747.0 415000.0 0.9 1.2202 0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 N24 mock treatment 366508.0 141000.0 0.29 382498.0 146000.0 0.32 0.4282 0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O01 mock treatment 10052.0 -216000.0 -0.45 12471.0 -224000.0 -0.49 -0.6584 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O02 mock treatment 9445.0 -217000.0 -0.45 12503.0 -224000.0 -0.49 -0.6593 -0.9992 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O03 compound treatment 560682.0 335000.0 0.69 665946.0 429000.0 0.93 1.1454 0.9894 1924268 CBMicro_001881 COc1cc(cc(OC)c1OC)C2=N/C(=C\N(C)C)/C(=O)O2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O04 compound treatment 522042.0 296000.0 0.61 620363.0 384000.0 0.83 1.0193 0.9886 1924269 CBMicro_001882 FC(F)(F)COS(=O)(=O)CCSc1ccc(Cl)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O05 compound treatment 548745.0 323000.0 0.67 659276.0 423000.0 0.91 1.1178 0.9879 1707478 CBMicro_001883 CCOC(=O)c1sc(NC(=O)c2cncc(Br)c2)c(C(=O)OCC)c1C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O06 compound treatment 530817.0 305000.0 0.63 614842.0 378000.0 0.82 1.0236 0.9916 1924270 CBMicro_001884 CC/C(=N\N=C(/CC)\c1ccccc1N)/c2ccccc2N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O07 compound treatment 553733.0 328000.0 0.68 672694.0 436000.0 0.94 1.1456 0.9867 1924271 CBMicro_001885 CC(=O)c1c(OC(=O)c2ccco2)ccc3c(C)cc(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O08 compound treatment 542920.0 317000.0 0.65 616460.0 380000.0 0.82 1.0438 0.9936 1924272 CBMicro_001886 OC1=N/C(=N/N=C/C=C/c2ccccc2)/SC1CC(=O)Nc3ccc(Cl)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O09 compound treatment 553682.0 328000.0 0.68 653357.0 417000.0 0.9 1.116 0.99 1555961 CBMicro_001887 CC(=O)Nc1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O10 compound treatment 558964.0 333000.0 0.69 614129.0 377000.0 0.82 1.0636 0.9963 1533872 CBMicro_001888 CC(=O)Oc1ccc(cc1)N2C(=O)C3CC(=C(C)CC3C2=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O11 compound treatment 583235.0 357000.0 0.74 666971.0 430000.0 0.93 1.1799 0.9933 1924273 CBMicro_001889 Clc1cccc(NC(=S)NC(=O)c2ccco2)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O12 compound treatment 548107.0 322000.0 0.66 633542.0 397000.0 0.86 1.0775 0.992 1427905 CBMicro_001890 Cc1c(OCC(=O)OCc2ccccc2)ccc3c4CCCc4c(=O)oc13 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O13 compound treatment 584118.0 358000.0 0.74 633163.0 396000.0 0.86 1.1295 0.9972 1696195 CBMicro_001891 CCOC(=O)C(C)Oc1cc2oc(=O)cc(c3ccccc3)c2cc1CC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O14 compound treatment 568905.0 343000.0 0.71 683253.0 447000.0 0.97 1.1839 0.9883 1031858 CBMicro_001892 Clc1ccc(cc1)N2COc3ccc4ccccc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O15 compound treatment 606694.0 381000.0 0.79 670894.0 434000.0 0.94 1.2202 0.996 1924274 CBMicro_001893 Brc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)C(=O)Nc3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O16 compound treatment 575281.0 349000.0 0.72 631477.0 395000.0 0.85 1.114 0.9964 1228696 CBMicro_001894 CCOC(=O)C(C)Oc1cccc2c1ccc3c(cc(=O)oc32)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O17 compound treatment 631283.0 405000.0 0.84 680973.0 444000.0 0.96 1.2715 0.9976 1924275 CBMicro_001895 COc1ccccc1c2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O18 compound treatment 601859.0 376000.0 0.78 645794.0 409000.0 0.89 1.1747 0.9978 1924276 CBMicro_001896 OC1=N/C(=N/N=C/c2ccco2)/SC1CC(=O)Nc3cccc(Cl)c3Cl 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O19 compound treatment 623775.0 398000.0 0.82 682451.0 446000.0 0.96 1.2628 0.9968 1168331 CBMicro_001897 CC(C)OC(=O)COc1ccc2c(cc(=O)oc2c1)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O20 compound treatment 586433.0 360000.0 0.74 649449.0 413000.0 0.89 1.1578 0.9959 1924277 CBMicro_001898 Brc1cccc(NC(=O)CN2C(=O)/C(=C/c3ccccc3)/SC2=S)c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O21 compound treatment 628549.0 403000.0 0.83 675028.0 438000.0 0.95 1.2584 0.9978 1287665 CBMicro_001899 C=CCn1c(CSc2nc3ccccc3s2)n[nH]c1=S 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O22 compound treatment 596531.0 371000.0 0.76 631345.0 395000.0 0.85 1.1448 0.9985 1924278 CBMicro_001900 COc1ccc(C/C(=N/OC(=O)COc2ccc3ccccc3c2)/N)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O23 mock treatment 598859.0 373000.0 0.77 676111.0 439000.0 0.95 1.2167 0.9945 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 O24 mock treatment 372110.0 146000.0 0.3 165934.0 -70800.0 -0.15 0.1049 0.3102 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P01 mock treatment 10084.0 -216000.0 -0.45 12901.0 -224000.0 -0.48 -0.6577 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P02 mock treatment 10157.0 -216000.0 -0.45 12796.0 -224000.0 -0.48 -0.6578 -0.9991 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P03 compound treatment 525811.0 300000.0 0.62 592753.0 356000.0 0.77 0.9825 0.9941 1521082 CBMicro_001901 COc1ccc(cc1Br)S(=O)(=O)Nc2ccccc2C(=O)N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P04 compound treatment 553882.0 328000.0 0.68 621250.0 385000.0 0.83 1.0671 0.9947 1924279 CBMicro_001902 COc1ccc(/C=C\2/N=C(N(C2=O)c3ccc(O)cc3)c4cccc(C)c4)cc1OC 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P05 compound treatment 526491.0 300000.0 0.62 599842.0 363000.0 0.79 0.9944 0.9931 1400547 CBMicro_001903 Cc1cc(OCC(=O)OC(C)(C)C)c2c3CCCc3c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P06 compound treatment 539762.0 314000.0 0.65 603371.0 367000.0 0.79 1.0191 0.9949 1924280 CBMicro_001904 ClC1=C(NCCc2ccccc2)C(=O)N(C1=O)c3ccc(Br)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P07 compound treatment 535037.0 309000.0 0.64 586478.0 350000.0 0.76 0.9864 0.9964 1129917 CBMicro_001905 CCOC(=O)C(C)Oc1ccc2c(C)c(C)c(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P08 compound treatment 550539.0 325000.0 0.67 583884.0 347000.0 0.75 1.005 0.9984 1924281 CBMicro_001906 Fc1ccc(NC(=O)CN2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P09 compound treatment 556113.0 330000.0 0.68 580555.0 344000.0 0.74 1.0081 0.999 1924282 CBMicro_001907 OC(=O)c1ccc(NC2=C(Cl)C(=O)N(C2=O)c3cccc(Cl)c3)cc1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P10 compound treatment 541088.0 315000.0 0.65 581353.0 345000.0 0.75 0.9874 0.9977 1924283 CBMicro_001908 CC(C)Oc1ccc(cc1)C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P11 compound treatment 585855.0 360000.0 0.74 581223.0 345000.0 0.75 1.0525 1.0 1326504 CBMicro_001909 Cc1nc2c(Cl)cccc2c(O)c1CN3CCOCC3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P12 compound treatment 648680.0 423000.0 0.87 570904.0 334000.0 0.72 1.1284 0.9957 1409107 CBMicro_001910 CCOC(=O)C1CCN(CC1)C(=O)C(c2ccccc2)c3ccccc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P13 compound treatment 558679.0 333000.0 0.69 572550.0 336000.0 0.73 0.9996 0.9996 1924284 CBMicro_001911 COc1ccccc1C/C(=N/OC(=O)COc2ccc3ccccc3c2)/N 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P14 compound treatment 556030.0 330000.0 0.68 581909.0 345000.0 0.75 1.01 0.9989 1924285 CBMicro_001912 Cc1cc(OCc2ccc(F)cc2)c3c4CCCc4c(=O)oc3c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P15 compound treatment 562863.0 337000.0 0.7 592703.0 356000.0 0.77 1.0365 0.9987 1924286 CBMicro_001913 CCOc1ccc2c(CC)cc(=O)oc2c1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P16 compound treatment 566119.0 340000.0 0.7 620144.0 383000.0 0.83 1.0833 0.9965 1924287 CBMicro_001914 Cc1cccc(c1)c2noc(n2)C(c3ccccc3)c4ccccc4 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P17 compound treatment 586942.0 361000.0 0.75 631073.0 394000.0 0.85 1.1304 0.9977 1924288 CBMicro_001915 COC(=O)C/1=C(C)N(C(=O)\C1=C/c2ccc(O)cc2)c3ccc(OC)cc3 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P18 compound treatment 592055.0 366000.0 0.76 628672.0 392000.0 0.85 1.1342 0.9983 1924289 CBMicro_001916 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(C)cc(=O)oc3c2C(=O)C 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P19 compound treatment 584213.0 358000.0 0.74 596358.0 360000.0 0.78 1.0733 0.9997 1256957 CBMicro_001917 Cc1cc(Cl)ccc1OC(=O)CCN2C(=O)c3ccccc3C2=O 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P20 compound treatment 586472.0 360000.0 0.74 584854.0 348000.0 0.75 1.059 1.0 1318772 CBMicro_001918 CCOC(=O)c1ccc(cc1)N2COc3ccc4ccccc4c3C2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P21 compound treatment 590870.0 365000.0 0.75 594627.0 358000.0 0.77 1.0804 0.9999 1784912 CBMicro_001919 O=C(Nc1ccccc1)c2ccc(NS(=O)(=O)c3ccccc3)cc2 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P22 compound treatment 588269.0 362000.0 0.75 611914.0 375000.0 0.81 1.103 0.9992 1924290 CBMicro_001920 Cc1ccc(/C=N/N=C/2\SC(CC(=O)Nc3ccccc3C(F)(F)F)C(=N2)O)o1 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P23 mock treatment 564324.0 338000.0 0.7 620742.0 384000.0 0.83 1.0816 0.9963 299.0537 raw{Pol(s)}(299.0537) CMVPolymeraseBindingAssay 299.0537.691 P24 mock treatment 388635.0 163000.0 0.34 173515.0 -63200.0 -0.14 0.1407 0.388