ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A01 compound treatment 492372.0 -79700.0 -0.36 563640.0 12300.0 0.06 -0.2092 -0.5777 1315851 ChemDiv1_002817 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)C(C)(C)C)c3ccccc3c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A02 compound treatment 508410.0 -63700.0 -0.29 556237.0 4920.0 0.02 -0.1844 -0.6443 1971663 ChemDiv1_002818 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A03 compound treatment 582939.0 10800.0 0.05 588033.0 36700.0 0.18 0.1629 0.8654 1971664 ChemDiv1_002819 COc1ccc(cc1)C(=O)Oc2ccc(C)cc2/C=C/3\Sc4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A04 compound treatment 550713.0 -21400.0 -0.1 557887.0 6570.0 0.03 -0.0447 -0.4418 1971665 ChemDiv1_002820 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A05 compound treatment 540084.0 -32000.0 -0.14 566565.0 15300.0 0.08 -0.0479 -0.2958 1971666 ChemDiv1_002821 O=c1oc(/C=C/c2ccco2)nc3sc4CCCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A06 compound treatment 558094.0 -14000.0 -0.06 597565.0 46300.0 0.23 0.1177 0.4953 1971667 ChemDiv1_002822 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(OC)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A07 compound treatment 588180.0 16100.0 0.07 621060.0 69700.0 0.35 0.2952 0.8364 1971668 ChemDiv1_002823 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(Cl)cc3)C(=O)O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A08 compound treatment 596659.0 24600.0 0.11 612784.0 61500.0 0.3 0.293 0.9052 1971669 ChemDiv1_002824 COC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cc(Cl)ccc3Cl)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A09 compound treatment 585941.0 13800.0 0.06 612411.0 61100.0 0.3 0.2578 0.8345 1971670 ChemDiv1_002825 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccccc4OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A10 compound treatment 614243.0 42100.0 0.19 613969.0 62700.0 0.31 0.3529 0.9715 1971671 ChemDiv1_002826 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A11 compound treatment 578167.0 6060.0 0.03 595503.0 44200.0 0.22 0.174 0.7887 1971672 ChemDiv1_002827 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A12 compound treatment 616539.0 44400.0 0.2 621452.0 70100.0 0.35 0.3863 0.965 1941012 ChemDiv1_002828 ClC1=CCC2C(C1)C(=O)N(CN(CN3C(=O)C4CC=C(Cl)CC4C3=O)Cc5ccco5)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A13 compound treatment 564405.0 -7700.0 -0.03 602494.0 51200.0 0.25 0.1549 0.6054 1971673 ChemDiv1_002829 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)cc3C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A14 compound treatment 597206.0 25100.0 0.11 605850.0 54500.0 0.27 0.2705 0.9244 1971674 ChemDiv1_002830 CC(C)Nc1nc(NC(C)C)nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A15 compound treatment 613618.0 41500.0 0.19 610573.0 59300.0 0.29 0.339 0.9757 1971675 ChemDiv1_002831 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OC)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A16 compound treatment 600742.0 28600.0 0.13 612457.0 61100.0 0.3 0.3048 0.9268 1302605 ChemDiv1_002832 CCN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A17 compound treatment 597528.0 25400.0 0.11 612566.0 61300.0 0.3 0.295 0.9104 1971676 ChemDiv1_002833 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OC)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A18 compound treatment 592163.0 20100.0 0.09 592137.0 40800.0 0.2 0.2065 0.9332 1348235 ChemDiv1_002834 COC(=O)CN(C#N)c1nc(NCc2ccccc2)nc(OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A19 compound treatment 574562.0 2460.0 0.01 596397.0 45100.0 0.22 0.1657 0.741 1971677 ChemDiv1_002835 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OC)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A20 compound treatment 561475.0 -10600.0 -0.05 570425.0 19100.0 0.09 0.0333 0.3143 1971678 ChemDiv1_002836 CCOC(=O)c1sc(NC(=O)Cn2nc([N+](=O)[O-])c([N+](=O)[O-])c2C)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A21 compound treatment 558223.0 -13900.0 -0.06 575511.0 24200.0 0.12 0.0408 0.3024 1971679 ChemDiv1_002837 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Cl)c(c3)C(F)(F)F)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A22 compound treatment 565298.0 -6810.0 -0.03 567889.0 16600.0 0.08 0.0365 0.417 1971680 ChemDiv1_002838 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(cc4)C(=O)C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A23 mock treatment 525977.0 -46100.0 -0.21 552938.0 1630.0 0.01 -0.1403 -0.679 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 A24 mock treatment 473915.0 -98200.0 -0.44 512344.0 -39000.0 -0.19 -0.4473 -0.9318 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B01 compound treatment 541077.0 -31000.0 -0.14 574357.0 23000.0 0.11 -0.0175 -0.0973 1971681 ChemDiv1_002839 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4cccc(c4)C(=O)C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B02 compound treatment 570509.0 -1600.0 -0.01 609505.0 58200.0 0.29 0.1988 0.6894 1971682 ChemDiv1_002840 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B03 compound treatment 620816.0 48700.0 0.22 634076.0 82800.0 0.41 0.4441 0.9563 1971683 ChemDiv1_002841 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4c(C)n(C)n(c5ccccc5)c4=O)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B04 compound treatment 615469.0 43400.0 0.19 622458.0 71100.0 0.35 0.3865 0.9605 1971684 ChemDiv1_002842 Cc1ccc2[nH]c(SCC(=O)Nc3ccccc3C(F)(F)F)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B05 compound treatment 658322.0 86200.0 0.39 658376.0 107000.0 0.53 0.6479 0.9878 1971685 ChemDiv1_002843 CN(Cc1ccccc1)C(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B06 compound treatment 624048.0 51900.0 0.23 640219.0 88900.0 0.44 0.4758 0.9554 1324538 ChemDiv1_002844 COC(=O)c1ccccc1NC(=O)CSc2nc3cc(OC)ccc3[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B07 compound treatment 652609.0 80500.0 0.36 679721.0 128000.0 0.64 0.7046 0.9638 1971686 ChemDiv1_002845 Fc1ccc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B08 compound treatment 660830.0 88700.0 0.4 659100.0 108000.0 0.53 0.6584 0.9894 1259663 ChemDiv1_002846 O=C(Nc1ccc(cc1)c2cc3ccccc3oc2=O)c4ccc5OCCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B09 compound treatment 663391.0 91300.0 0.41 684860.0 134000.0 0.66 0.7567 0.9732 1971687 ChemDiv1_002847 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B10 compound treatment 670883.0 98800.0 0.44 652476.0 101000.0 0.5 0.667 0.9981 1971688 ChemDiv1_002848 OC(=O)c1ccc(COc2ccc(C=C3C(=O)NC(=S)NC3=O)cc2Br)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B11 compound treatment 677606.0 106000.0 0.47 679166.0 128000.0 0.63 0.7818 0.9896 1971689 ChemDiv1_002849 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B12 compound treatment 638009.0 65900.0 0.3 702068.0 151000.0 0.75 0.7367 0.9174 1945511 ChemDiv1_002850 Cc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B13 compound treatment 660838.0 88700.0 0.4 680149.0 129000.0 0.64 0.7322 0.974 1971690 ChemDiv1_002851 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)c(OC)c4)C(=O)OCCOc5ccccc5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B14 compound treatment 675676.0 104000.0 0.46 659262.0 108000.0 0.53 0.706 0.9975 1971691 ChemDiv1_002852 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B15 compound treatment 639472.0 67400.0 0.3 685015.0 134000.0 0.66 0.6816 0.9365 1266671 ChemDiv1_002853 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B16 compound treatment 665933.0 93800.0 0.42 663981.0 113000.0 0.56 0.6917 0.9902 1971692 ChemDiv1_002854 CCCOc1ccc(OCCSc2nc3ccccc3n2CC(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B17 compound treatment 680608.0 109000.0 0.49 680743.0 129000.0 0.64 0.7968 0.9906 1546931 ChemDiv1_002855 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B18 compound treatment 660060.0 88000.0 0.39 652569.0 101000.0 0.5 0.6331 0.9928 1684044 ChemDiv1_002856 O=C(On1c(nc2ccccc2c1=O)c3ccccc3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B19 compound treatment 675940.0 104000.0 0.46 664145.0 113000.0 0.56 0.7239 0.9958 1199419 ChemDiv1_002857 COC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B20 compound treatment 611219.0 39100.0 0.18 630875.0 79600.0 0.39 0.4025 0.9333 1187744 ChemDiv1_002858 Clc1nc(NCc2ccco2)nc(Nc3nc(cs3)c4ccccc4)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B21 compound treatment 658938.0 86800.0 0.39 648839.0 97500.0 0.48 0.6165 0.9942 1943418 ChemDiv1_002859 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B22 compound treatment 619727.0 47600.0 0.21 611526.0 60200.0 0.3 0.3617 0.9864 1468275 ChemDiv1_002860 COc1ccccc1NC2CC(C)N(C(=O)c3ccc(C)cc3)c4c(C)cccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B23 mock treatment 582450.0 10300.0 0.05 607690.0 56400.0 0.28 0.2302 0.8133 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 B24 mock treatment 471287.0 -101000.0 -0.45 284282.0 -267000.0 -1.32 -1.2545 -0.8975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C01 compound treatment 548321.0 -23800.0 -0.11 586793.0 35500.0 0.18 0.049 0.2385 1493276 ChemDiv1_002861 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)Cc3ccccc3)c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C02 compound treatment 583916.0 11800.0 0.05 587783.0 36500.0 0.18 0.1651 0.8772 1971693 ChemDiv1_002862 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C03 compound treatment 618282.0 46200.0 0.21 622780.0 71500.0 0.35 0.3965 0.9672 1971694 ChemDiv1_002863 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C04 compound treatment 621712.0 49600.0 0.22 621072.0 69800.0 0.35 0.4014 0.9771 1971695 ChemDiv1_002864 COc1ccccc1NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccccc4)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C05 compound treatment 639773.0 67700.0 0.3 627347.0 76000.0 0.38 0.4805 0.9942 1605374 ChemDiv1_002865 CCOc1ccc(cc1)n2c(C)c(C(=O)OC3CCCCC3)c4cc(OC)ccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C06 compound treatment 620752.0 48600.0 0.22 621584.0 70300.0 0.35 0.4001 0.9745 1971696 ChemDiv1_002866 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C07 compound treatment 657918.0 85800.0 0.38 680435.0 129000.0 0.64 0.7239 0.9702 1971697 ChemDiv1_002867 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc(OC)cc3)C(=O)Nc4ccccc4OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C08 compound treatment 701818.0 130000.0 0.58 671172.0 120000.0 0.59 0.8304 0.9999 1971698 ChemDiv1_002868 OC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C09 compound treatment 686165.0 114000.0 0.51 669054.0 118000.0 0.58 0.7735 0.9978 1971699 ChemDiv1_002869 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C10 compound treatment 682424.0 110000.0 0.49 665487.0 114000.0 0.57 0.7491 0.9977 1971700 ChemDiv1_002870 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C11 compound treatment 719572.0 147000.0 0.66 681517.0 130000.0 0.65 0.9229 0.9999 1971701 ChemDiv1_002871 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OC)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C12 compound treatment 674688.0 103000.0 0.46 664726.0 113000.0 0.56 0.722 0.995 1689943 ChemDiv1_002872 COC(=O)CN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C13 compound treatment 682196.0 110000.0 0.49 661804.0 110000.0 0.55 0.7355 0.9986 1971702 ChemDiv1_002873 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3Cl)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C14 compound treatment 697894.0 126000.0 0.56 674560.0 123000.0 0.61 0.8299 0.9992 1782850 ChemDiv1_002874 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C15 compound treatment 731216.0 159000.0 0.71 670241.0 119000.0 0.59 0.9202 0.9956 1971703 ChemDiv1_002875 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(F)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C16 compound treatment 700330.0 128000.0 0.57 665689.0 114000.0 0.57 0.8065 1.0 1971704 ChemDiv1_002876 CCN(CC)CCCN1C(=O)C2C(C3C2C4C=CC3C5C4C(=O)N(CCCN(CC)CC)C5=O)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C17 compound treatment 718469.0 146000.0 0.66 674626.0 123000.0 0.61 0.8952 0.9994 1971705 ChemDiv1_002877 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(Br)cc3)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C18 compound treatment 669013.0 96900.0 0.43 628651.0 77300.0 0.38 0.5776 0.9981 1441771 ChemDiv1_002878 CCOC(=O)CSc1nc2-c3ccccc3CC(CC)(C4CCCCC4)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C19 compound treatment 661550.0 89400.0 0.4 637478.0 86200.0 0.43 0.5849 0.9995 1971706 ChemDiv1_002879 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C20 compound treatment 613396.0 41300.0 0.18 611642.0 60300.0 0.3 0.342 0.9733 1971707 ChemDiv1_002880 Cc1c([N+](=O)[O-])c(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C21 compound treatment 696424.0 124000.0 0.56 642133.0 90800.0 0.45 0.7116 0.9944 1971708 ChemDiv1_002881 CN/1C(=O)CC(S\C1=N/c2ccc(Cl)c(c2)C(F)(F)F)C(=O)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C22 compound treatment 595128.0 23000.0 0.1 610659.0 59300.0 0.29 0.2808 0.9012 1971709 ChemDiv1_002882 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4ccc5OCOc5c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C23 mock treatment 681483.0 109000.0 0.49 610404.0 59100.0 0.29 0.5532 0.9698 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 C24 mock treatment 476564.0 -95500.0 -0.43 502348.0 -49000.0 -0.24 -0.4739 -0.9639 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D01 compound treatment 544709.0 -27400.0 -0.12 570397.0 19100.0 0.09 -0.0199 -0.1283 1971710 ChemDiv1_002883 CCOC(=O)c1c(NC(=O)c2cnn3c(cc(nc23)c4ccco4)C(F)(F)F)sc5CCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D02 compound treatment 594666.0 22600.0 0.1 589539.0 38200.0 0.19 0.2053 0.9567 1971711 ChemDiv1_002884 CC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D03 compound treatment 639027.0 66900.0 0.3 643898.0 92600.0 0.46 0.5361 0.9787 1971712 ChemDiv1_002885 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4cccnc4Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D04 compound treatment 639842.0 67700.0 0.3 632181.0 80900.0 0.4 0.4977 0.9906 1214132 ChemDiv1_002886 COc1ccc2nc(NC(=O)CSc3nc4cc(C)ccc4[nH]3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D05 compound treatment 672141.0 100000.0 0.45 648455.0 97100.0 0.48 0.6569 0.9994 1971713 ChemDiv1_002887 Fc1ccc(CNC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D06 compound treatment 665161.0 93100.0 0.42 636704.0 85400.0 0.42 0.5937 1.0 1230343 ChemDiv1_002888 COc1ccc(CNC(=O)CSc2nc3cc(OC)ccc3[nH]2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D07 compound treatment 675959.0 104000.0 0.46 662612.0 111000.0 0.55 0.7186 0.9964 1971714 ChemDiv1_002889 COc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D08 compound treatment 699442.0 127000.0 0.57 649914.0 98600.0 0.49 0.7484 0.997 1739426 ChemDiv1_002890 Cc1cc(C)c2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D09 compound treatment 720169.0 148000.0 0.66 648159.0 96800.0 0.48 0.8079 0.9874 1971715 ChemDiv1_002891 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCn3ccnc3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D10 compound treatment 707998.0 136000.0 0.61 664607.0 113000.0 0.56 0.827 0.9992 1945468 ChemDiv1_002892 CN1C(=O)NC(=O)/C(=C\c2ccc(OCc3ccc(cc3)C(=O)O)c(Br)c2)/C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D11 compound treatment 729745.0 158000.0 0.71 691268.0 140000.0 0.69 0.9892 1.0 1943239 ChemDiv1_002893 COCCNC(=O)c1nn2c(cc(nc2c1Cl)c3ccc(OC)c(OC)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D12 compound treatment 689549.0 117000.0 0.53 662318.0 111000.0 0.55 0.7606 0.9997 1945465 ChemDiv1_002894 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D13 compound treatment 711806.0 140000.0 0.63 672599.0 121000.0 0.6 0.867 0.9998 1971716 ChemDiv1_002895 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCOc4ccccc4)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D14 compound treatment 691412.0 119000.0 0.53 674240.0 123000.0 0.61 0.8082 0.9979 1971717 ChemDiv1_002896 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Cl)C(=O)CC(C2)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D15 compound treatment 729656.0 158000.0 0.71 704334.0 153000.0 0.76 1.0347 0.9994 1485964 ChemDiv1_002897 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D16 compound treatment 649594.0 77500.0 0.35 618179.0 66900.0 0.33 0.4795 0.9997 1784062 ChemDiv1_002898 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D17 compound treatment 662703.0 90600.0 0.41 686409.0 135000.0 0.67 0.76 0.9712 1971718 ChemDiv1_002899 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D18 compound treatment 693759.0 122000.0 0.54 647841.0 96500.0 0.48 0.7232 0.9979 1971719 ChemDiv1_002900 [O-][N+](=O)c1ccc(cc1)C(=O)CSc2nnc(o2)c3ccco3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D19 compound treatment 728962.0 157000.0 0.7 681012.0 130000.0 0.64 0.9508 0.999 1326627 ChemDiv1_002901 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2COc3ccccc3O2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D20 compound treatment 710401.0 138000.0 0.62 652891.0 102000.0 0.5 0.7936 0.9947 1279285 ChemDiv1_002902 C1CN(CCO1)c2nc(Nc3nc(cs3)c4ccccc4)nc(n2)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D21 compound treatment 678938.0 107000.0 0.48 668693.0 117000.0 0.58 0.7493 0.9953 1971720 ChemDiv1_002903 CC(=O)N1N=C(CC1c2ccccc2F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D22 compound treatment 689702.0 118000.0 0.53 628623.0 77300.0 0.38 0.643 0.9878 1395832 ChemDiv1_002904 COc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccc(C)cc3)c4ccc(C)cc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D23 mock treatment 680671.0 109000.0 0.49 624695.0 73400.0 0.36 0.6007 0.9898 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 D24 mock treatment 495481.0 -76600.0 -0.34 199275.0 -352000.0 -1.74 -1.4757 -0.8303 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E01 compound treatment 573377.0 1270.0 0.01 589219.0 37900.0 0.19 0.1368 0.7282 1297496 ChemDiv1_002905 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)COc3ccccc3)c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E02 compound treatment 592981.0 20900.0 0.09 586027.0 34700.0 0.17 0.1877 0.9589 1971721 ChemDiv1_002906 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E03 compound treatment 656816.0 84700.0 0.38 652896.0 102000.0 0.5 0.624 0.9903 1971722 ChemDiv1_002907 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E04 compound treatment 632405.0 60300.0 0.27 642090.0 90800.0 0.45 0.5088 0.9702 1971723 ChemDiv1_002908 O=C(Nc1ccccc1)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E05 compound treatment 670715.0 98600.0 0.44 661681.0 110000.0 0.55 0.6987 0.9944 1708247 ChemDiv1_002909 COc1ccc(cc1)c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E06 compound treatment 674508.0 102000.0 0.46 650905.0 99600.0 0.49 0.673 0.9993 1971724 ChemDiv1_002910 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(OC)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E07 compound treatment 662813.0 90700.0 0.41 656669.0 105000.0 0.52 0.6562 0.9923 1971725 ChemDiv1_002911 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E08 compound treatment 691957.0 120000.0 0.54 672909.0 122000.0 0.6 0.8053 0.9983 1971726 ChemDiv1_002912 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E09 compound treatment 719009.0 147000.0 0.66 680839.0 130000.0 0.64 0.9187 0.9999 1971727 ChemDiv1_002913 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E10 compound treatment 717939.0 146000.0 0.65 669375.0 118000.0 0.58 0.8752 0.9985 1971728 ChemDiv1_002914 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E11 compound treatment 719943.0 148000.0 0.66 701532.0 150000.0 0.74 0.9941 0.9983 1971729 ChemDiv1_002915 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(C)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E12 compound treatment 674518.0 102000.0 0.46 674537.0 123000.0 0.61 0.7558 0.99 1141939 ChemDiv1_002916 CN(C)c1nc(nc(n1)N(CCOc2ccccc2C)C#N)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E13 compound treatment 714172.0 142000.0 0.64 691308.0 140000.0 0.69 0.9401 0.9991 1971730 ChemDiv1_002917 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(OCC)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E14 compound treatment 718592.0 146000.0 0.66 690760.0 139000.0 0.69 0.9521 0.9997 1714810 ChemDiv1_002918 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E15 compound treatment 767721.0 196000.0 0.88 705972.0 155000.0 0.77 1.1609 0.9978 1971731 ChemDiv1_002919 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccccc3OC)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E16 compound treatment 699174.0 127000.0 0.57 650632.0 99300.0 0.49 0.7501 0.9974 1971732 ChemDiv1_002920 COc1ccccc1N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7ccccc7OC)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E17 compound treatment 728686.0 157000.0 0.7 705890.0 155000.0 0.77 1.0371 0.999 1971733 ChemDiv1_002921 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(Cl)c3)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E18 compound treatment 716107.0 144000.0 0.64 685191.0 134000.0 0.66 0.9248 0.9999 1528170 ChemDiv1_002922 Cn1c(SCC(=O)N2CCOCC2)nc3n(C)c(=O)n(C)c(=O)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E19 compound treatment 715989.0 144000.0 0.64 679669.0 128000.0 0.64 0.9051 1.0 1971734 ChemDiv1_002923 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(cc3)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E20 compound treatment 692350.0 120000.0 0.54 658403.0 107000.0 0.53 0.7557 1.0 1971735 ChemDiv1_002924 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(OC)cc4OC)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E21 compound treatment 667185.0 95100.0 0.43 676518.0 125000.0 0.62 0.7395 0.9831 1971736 ChemDiv1_002925 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E22 compound treatment 645233.0 73100.0 0.33 644595.0 93300.0 0.46 0.5582 0.9857 1971737 ChemDiv1_002926 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)NCC4CCCO4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E23 mock treatment 688619.0 117000.0 0.52 637242.0 85900.0 0.43 0.6698 0.9949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 E24 mock treatment 470732.0 -101000.0 -0.45 498192.0 -53100.0 -0.26 -0.5069 -0.9664 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F01 compound treatment 595554.0 23400.0 0.1 595448.0 44100.0 0.22 0.2288 0.9435 1971738 ChemDiv1_002927 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4cc(C)ccc4O)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F02 compound treatment 613189.0 41100.0 0.18 616181.0 64900.0 0.32 0.3573 0.9649 1206594 ChemDiv1_002928 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F03 compound treatment 657376.0 85300.0 0.38 656548.0 105000.0 0.52 0.6385 0.9883 1971739 ChemDiv1_002929 FC(F)(F)c1cc(nc2c(cnn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F04 compound treatment 662058.0 90000.0 0.4 622037.0 70700.0 0.35 0.5325 0.9976 1971740 ChemDiv1_002930 FC(F)(F)c1ccccc1NC(=O)CSc2nc3ccccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F05 compound treatment 686600.0 114000.0 0.51 659091.0 108000.0 0.53 0.7399 0.9998 1971741 ChemDiv1_002931 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)Nc3cccnc3Cl)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F06 compound treatment 688133.0 116000.0 0.52 675297.0 124000.0 0.61 0.8016 0.9965 1971742 ChemDiv1_002932 COc1cccc(NC(=O)CSc2nc3ccccc3n2C(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F07 compound treatment 696785.0 125000.0 0.56 681021.0 130000.0 0.64 0.849 0.9975 1971743 ChemDiv1_002933 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F08 compound treatment 727648.0 156000.0 0.7 681085.0 130000.0 0.64 0.9469 0.9992 1668404 ChemDiv1_002934 Fc1ccccc1c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F09 compound treatment 715119.0 143000.0 0.64 674716.0 123000.0 0.61 0.8849 0.9997 1971744 ChemDiv1_002935 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCN3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F10 compound treatment 722477.0 150000.0 0.67 666655.0 115000.0 0.57 0.88 0.9967 1971745 ChemDiv1_002936 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F11 compound treatment 717694.0 146000.0 0.65 695835.0 145000.0 0.72 0.9671 0.9989 1971746 ChemDiv1_002937 CCN(CC)CCCNC(=O)c1nn2c(cc(nc2c1Cl)c3ccc(OC)c(OC)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F12 compound treatment 697591.0 125000.0 0.56 682737.0 131000.0 0.65 0.8576 0.9973 1945437 ChemDiv1_002938 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F13 compound treatment 729784.0 158000.0 0.71 689490.0 138000.0 0.68 0.9831 0.9999 1938187 ChemDiv1_002939 COc1cccc(C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F14 compound treatment 737385.0 165000.0 0.74 677250.0 126000.0 0.62 0.9643 0.9964 1971747 ChemDiv1_002940 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F15 compound treatment 750271.0 178000.0 0.8 694703.0 143000.0 0.71 1.0662 0.9983 1716164 ChemDiv1_002941 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(F)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F16 compound treatment 738125.0 166000.0 0.74 658030.0 107000.0 0.53 0.8993 0.9861 1189094 ChemDiv1_002942 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F17 compound treatment 757022.0 185000.0 0.83 690783.0 139000.0 0.69 1.0739 0.996 1971748 ChemDiv1_002943 CC1=C(C(C2=C(CC(CC2=O)c3ccc(Cl)cc3)N1)c4cccnc4)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F18 compound treatment 727790.0 156000.0 0.7 674777.0 123000.0 0.61 0.9253 0.9979 1926772 ChemDiv1_002944 Brc1ccc(cc1)C(=O)CSc2nnc(o2)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F19 compound treatment 750334.0 178000.0 0.8 697666.0 146000.0 0.73 1.0768 0.9989 1971749 ChemDiv1_002945 CC/N=C/1\SC(CC(=O)Nc2ccc(F)cc2)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F20 compound treatment 713611.0 142000.0 0.63 648398.0 97100.0 0.48 0.788 0.9908 1971750 ChemDiv1_002946 FC(F)(F)c1cccc(NC(=O)CSc2nc3ccccc3o2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F21 compound treatment 709096.0 137000.0 0.61 672914.0 122000.0 0.6 0.8596 1.0 1928138 ChemDiv1_002947 OC(=O)CCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F22 compound treatment 711638.0 140000.0 0.62 642984.0 91700.0 0.45 0.7628 0.9877 1447227 ChemDiv1_002948 CC1CC(Nc2ccc(C)cc2)c3ccc(C)cc3N1C(=O)c4cccc(F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F23 mock treatment 633805.0 61700.0 0.28 626773.0 75500.0 0.37 0.4596 0.9889 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 F24 mock treatment 479945.0 -92200.0 -0.41 521170.0 -30100.0 -0.15 -0.3973 -0.9056 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G01 compound treatment 556170.0 -15900.0 -0.07 576450.0 25100.0 0.12 0.0376 0.2621 1240434 ChemDiv1_002949 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)COc3ccccc3C)c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G02 compound treatment 602920.0 30800.0 0.14 624747.0 73400.0 0.36 0.3548 0.9119 1971751 ChemDiv1_002950 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G03 compound treatment 648921.0 76800.0 0.34 648808.0 97500.0 0.48 0.5847 0.9861 1409622 ChemDiv1_002951 O=C1CCC(=O)N1c2ccc(cc2)c3nc4sc5CCCc5c4c(=O)o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G04 compound treatment 653037.0 80900.0 0.36 644527.0 93200.0 0.46 0.5827 0.9928 1971752 ChemDiv1_002952 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(Cl)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G05 compound treatment 687549.0 115000.0 0.52 662389.0 111000.0 0.55 0.7545 0.9995 1172543 ChemDiv1_002953 CC1(C)Cc2c(sc3ncn4nc(nc4c23)c5ccccc5O)C(C)(C)N1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G06 compound treatment 660666.0 88600.0 0.4 665759.0 114000.0 0.57 0.6812 0.9847 1971753 ChemDiv1_002954 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G07 compound treatment 694948.0 123000.0 0.55 672168.0 121000.0 0.6 0.8122 0.9991 1971754 ChemDiv1_002955 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccccc4OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G08 compound treatment 688083.0 116000.0 0.52 660531.0 109000.0 0.54 0.7497 0.9998 1971755 ChemDiv1_002956 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G09 compound treatment 716953.0 145000.0 0.65 674862.0 124000.0 0.61 0.8913 0.9996 1971756 ChemDiv1_002957 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(F)cc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G10 compound treatment 713724.0 142000.0 0.63 677264.0 126000.0 0.62 0.8895 1.0 1971757 ChemDiv1_002958 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccc(Cl)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G11 compound treatment 740630.0 169000.0 0.75 674518.0 123000.0 0.61 0.965 0.9945 1971758 ChemDiv1_002959 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G12 compound treatment 692196.0 120000.0 0.54 664401.0 113000.0 0.56 0.7763 0.9998 1971759 ChemDiv1_002960 CCN(CC)C(=O)CN(C#N)c1nc(nc(n1)N(C)C)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G13 compound treatment 705276.0 133000.0 0.6 673882.0 123000.0 0.61 0.8509 1.0 1971760 ChemDiv1_002961 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(cc3)C(=O)OCC)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G14 compound treatment 708278.0 136000.0 0.61 682090.0 131000.0 0.65 0.8891 0.9995 1228270 ChemDiv1_002962 CC(C)Sc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G15 compound treatment 759789.0 188000.0 0.84 690062.0 139000.0 0.69 1.0801 0.995 1971761 ChemDiv1_002963 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(F)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G16 compound treatment 718047.0 146000.0 0.65 679511.0 128000.0 0.64 0.911 0.9999 1971762 ChemDiv1_002964 Oc1cccc(c1)N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7cccc(O)c7)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G17 compound treatment 749769.0 178000.0 0.8 661559.0 110000.0 0.55 0.9485 0.9832 1971763 ChemDiv1_002965 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G18 compound treatment 700992.0 129000.0 0.58 669240.0 118000.0 0.58 0.821 1.0 1546202 ChemDiv1_002966 COC(=O)c1ccccc1NC(=O)Cn2c(SC)nc3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G19 compound treatment 715013.0 143000.0 0.64 700478.0 149000.0 0.74 0.9749 0.9974 1971764 ChemDiv1_002967 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G20 compound treatment 675344.0 103000.0 0.46 656266.0 105000.0 0.52 0.6944 0.9983 1928539 ChemDiv1_002968 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G21 compound treatment 698602.0 126000.0 0.57 668420.0 117000.0 0.58 0.8106 0.9999 1971765 ChemDiv1_002969 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N\c5ccc(F)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G22 compound treatment 658417.0 86300.0 0.39 644931.0 93600.0 0.46 0.6011 0.9959 1971766 ChemDiv1_002970 COc1ccc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G23 mock treatment 681777.0 110000.0 0.49 639943.0 88600.0 0.44 0.6576 0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 G24 mock treatment 539612.0 -32500.0 -0.15 513699.0 -37600.0 -0.19 -0.2346 -0.9925 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H01 compound treatment 579877.0 7770.0 0.03 580466.0 29200.0 0.14 0.1267 0.8531 1971767 ChemDiv1_002971 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4ccc(cc4)C(=O)C)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H02 compound treatment 602611.0 30500.0 0.14 587199.0 35900.0 0.18 0.2223 0.9915 1971768 ChemDiv1_002972 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)c5ccncc5)c(c6ccccc6)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H03 compound treatment 649240.0 77100.0 0.35 646162.0 94800.0 0.47 0.5764 0.9885 1971769 ChemDiv1_002973 COc1ccc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H04 compound treatment 648381.0 76300.0 0.34 634539.0 83200.0 0.41 0.533 0.9956 1971770 ChemDiv1_002974 CC(=O)c1ccc(NC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H05 compound treatment 675131.0 103000.0 0.46 669273.0 118000.0 0.58 0.7393 0.9931 1971771 ChemDiv1_002975 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3nn4c(cc(nc4c3Cl)c5ccco5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H06 compound treatment 684612.0 113000.0 0.5 645690.0 94400.0 0.47 0.6867 0.9993 1971772 ChemDiv1_002976 CC1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H07 compound treatment 707245.0 135000.0 0.6 674985.0 124000.0 0.61 0.861 1.0 1971773 ChemDiv1_002977 COc1cc(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H08 compound treatment 718624.0 147000.0 0.66 630236.0 78900.0 0.39 0.7402 0.9694 1532693 ChemDiv1_002978 COc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H09 compound treatment 709869.0 138000.0 0.62 675457.0 124000.0 0.61 0.8709 1.0 1971774 ChemDiv1_002979 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCN(C)CC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H10 compound treatment 713268.0 141000.0 0.63 663665.0 112000.0 0.56 0.8404 0.998 1945601 ChemDiv1_002980 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H11 compound treatment 749181.0 177000.0 0.79 700066.0 149000.0 0.74 1.0816 0.9993 1399164 ChemDiv1_002981 O=C(Nc1ccc(cc1)c2nc3ncccc3o2)c4ccc5CCc6cccc4c65 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H12 compound treatment 706655.0 135000.0 0.6 677992.0 127000.0 0.63 0.8696 0.9998 1971775 ChemDiv1_002982 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H13 compound treatment 731443.0 159000.0 0.71 690290.0 139000.0 0.69 0.9912 0.9998 1327648 ChemDiv1_002983 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H14 compound treatment 743993.0 172000.0 0.77 680330.0 129000.0 0.64 0.996 0.9957 1971776 ChemDiv1_002984 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H15 compound treatment 759568.0 187000.0 0.84 688050.0 137000.0 0.68 1.0723 0.9944 1784055 ChemDiv1_002985 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H16 compound treatment 727396.0 155000.0 0.7 658790.0 107000.0 0.53 0.868 0.9913 1726949 ChemDiv1_002986 CCOC(=O)c1c(CN2CCC(C)CC2)n(C)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H17 compound treatment 751831.0 180000.0 0.8 718909.0 168000.0 0.83 1.156 0.9999 1340179 ChemDiv1_002987 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)c(OC)c(OC)c4)C(=O)OCC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H18 compound treatment 686605.0 115000.0 0.51 630669.0 79400.0 0.39 0.6404 0.9914 1938496 ChemDiv1_002988 COc1ccc(Nc2nc(Nc3ccc(cc3)[N+](=O)[O-])nc(OC)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H19 compound treatment 723235.0 151000.0 0.68 672361.0 121000.0 0.6 0.9024 0.9982 1950508 ChemDiv1_002989 CC/N=C/1\SC(CC(=O)Nc2ccccc2C#N)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H20 compound treatment 705709.0 134000.0 0.6 662476.0 111000.0 0.55 0.8123 0.9992 1971777 ChemDiv1_002990 Cc1ccc2[nH]c(SCC(=O)Nc3cccc(c3)C(F)(F)F)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H21 compound treatment 727434.0 155000.0 0.7 668234.0 117000.0 0.58 0.9012 0.9959 1971778 ChemDiv1_002991 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H22 compound treatment 714341.0 142000.0 0.64 646209.0 94900.0 0.47 0.7826 0.9889 1344202 ChemDiv1_002992 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)COc4ccc5ccccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H23 mock treatment 685946.0 114000.0 0.51 646755.0 95400.0 0.47 0.6947 0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 H24 mock treatment 484017.0 -88100.0 -0.39 519472.0 -31800.0 -0.16 -0.3904 -0.9192 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I01 compound treatment 529993.0 -42100.0 -0.19 564996.0 13700.0 0.07 -0.0854 -0.4261 1971779 ChemDiv1_002993 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc4ccccc34)c5ccccc5c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I02 compound treatment 581712.0 9610.0 0.04 601672.0 50400.0 0.25 0.2068 0.817 1971780 ChemDiv1_002994 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I03 compound treatment 628221.0 56100.0 0.25 622627.0 71300.0 0.35 0.4274 0.986 1277715 ChemDiv1_002995 Cc1sc2nc(oc(=O)c2c1C)c3ccc(cc3)N4C(=O)CCC4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I04 compound treatment 651410.0 79300.0 0.36 612010.0 60700.0 0.3 0.4636 0.9966 1971781 ChemDiv1_002996 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I05 compound treatment 664108.0 92000.0 0.41 628475.0 77200.0 0.38 0.5615 0.9993 1210048 ChemDiv1_002997 COc1ccc(cc1OC)c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I06 compound treatment 674938.0 103000.0 0.46 650817.0 99500.0 0.49 0.674 0.9994 1971782 ChemDiv1_002998 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccccc4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I07 compound treatment 689904.0 118000.0 0.53 663264.0 112000.0 0.55 0.765 0.9997 1971783 ChemDiv1_002999 COc1ccccc1NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I08 compound treatment 700564.0 128000.0 0.58 671845.0 121000.0 0.6 0.8288 0.9998 1971784 ChemDiv1_003000 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccc(F)cc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I09 compound treatment 700397.0 128000.0 0.57 662595.0 111000.0 0.55 0.7959 0.9998 1971785 ChemDiv1_003001 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I10 compound treatment 707749.0 136000.0 0.61 662876.0 112000.0 0.55 0.8201 0.9989 1971786 ChemDiv1_003002 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(Cl)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I11 compound treatment 732682.0 161000.0 0.72 672341.0 121000.0 0.6 0.9322 0.9959 1971787 ChemDiv1_003003 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(F)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I12 compound treatment 654810.0 82700.0 0.37 648280.0 97000.0 0.48 0.6015 0.9917 1293063 ChemDiv1_003004 COc1ccccc1OCCN(C#N)c2nc(nc(n2)N(C)C)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I13 compound treatment 704046.0 132000.0 0.59 654530.0 103000.0 0.51 0.7792 0.9974 1971788 ChemDiv1_003005 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I14 compound treatment 714759.0 143000.0 0.64 656241.0 105000.0 0.52 0.8191 0.9948 1642630 ChemDiv1_003006 CN1Cc2c(nc3sc(C(=O)c4ccccc4)c(N)c3c2CC1(C)C)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I15 compound treatment 746867.0 175000.0 0.78 685644.0 134000.0 0.67 1.0237 0.9968 1971789 ChemDiv1_003007 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(c3)C(F)(F)F)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I16 compound treatment 712590.0 140000.0 0.63 661549.0 110000.0 0.55 0.8308 0.9975 1971790 ChemDiv1_003008 Oc1ccc(cc1)N2C(=O)C3C(C4C3C5C=CC4C6C5C(=O)N(C6=O)c7ccc(O)cc7)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I17 compound treatment 743351.0 171000.0 0.77 695119.0 144000.0 0.71 1.0458 0.9993 1971791 ChemDiv1_003009 COc1ccccc1NC(=O)C2CC(=O)N(C)/C(=N\c3cccc(c3)C(F)(F)F)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I18 compound treatment 680378.0 108000.0 0.48 662781.0 111000.0 0.55 0.7332 0.9979 1170886 ChemDiv1_003010 COC(=O)c1ccccc1NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I19 compound treatment 700259.0 128000.0 0.57 672980.0 122000.0 0.6 0.8318 0.9997 1971792 ChemDiv1_003011 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(C)c(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I20 compound treatment 674363.0 102000.0 0.46 653834.0 103000.0 0.51 0.6828 0.9987 1971793 ChemDiv1_003012 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)NCCCn3ccnc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I21 compound treatment 710961.0 139000.0 0.62 674184.0 123000.0 0.61 0.8699 0.9999 1971794 ChemDiv1_003013 Fc1ccc(/N=C\2/SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I22 compound treatment 667393.0 95300.0 0.43 609001.0 57700.0 0.29 0.5037 0.981 1971795 ChemDiv1_003014 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)Nc4cccc(c4)C(=O)C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I23 mock treatment 690398.0 118000.0 0.53 599402.0 48100.0 0.24 0.5429 0.935 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 I24 mock treatment 479003.0 -93100.0 -0.42 510696.0 -40600.0 -0.2 -0.437 -0.9442 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J01 compound treatment 573247.0 1140.0 0.01 592981.0 41700.0 0.21 0.1496 0.7244 1971796 ChemDiv1_003015 COc1ccc(NC(=O)c2cnn3c(cc(nc23)c4cc(OC)c(OC)c(OC)c4)C(F)(F)F)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J02 compound treatment 612780.0 40700.0 0.18 632223.0 80900.0 0.4 0.4122 0.9362 1971797 ChemDiv1_003016 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)c5cccnc5)c(c6ccccc6)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J03 compound treatment 654317.0 82200.0 0.37 638039.0 86700.0 0.43 0.564 0.997 1971798 ChemDiv1_003017 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCCN3CCOCC3)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J04 compound treatment 636011.0 63900.0 0.29 623766.0 72500.0 0.36 0.4561 0.9937 1971799 ChemDiv1_003018 COc1ccc2nc(NC(=O)CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J05 compound treatment 677916.0 106000.0 0.47 665574.0 114000.0 0.57 0.7352 0.9961 1943197 ChemDiv1_003019 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J06 compound treatment 663939.0 91800.0 0.41 638330.0 87000.0 0.43 0.5955 0.9997 1634373 ChemDiv1_003020 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J07 compound treatment 687015.0 115000.0 0.51 676215.0 125000.0 0.62 0.8012 0.9958 1943209 ChemDiv1_003021 COc1ccc(cc1)c2cc(n3nc(C(=O)N4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J08 compound treatment 675013.0 103000.0 0.46 664205.0 113000.0 0.56 0.7212 0.9954 1396140 ChemDiv1_003022 Cc1ccc(cc1Cl)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J09 compound treatment 735043.0 163000.0 0.73 686859.0 136000.0 0.67 0.9905 0.9991 1971800 ChemDiv1_003023 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J10 compound treatment 720729.0 149000.0 0.67 678040.0 127000.0 0.63 0.9143 0.9996 1945399 ChemDiv1_003024 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J11 compound treatment 724120.0 152000.0 0.68 691372.0 140000.0 0.69 0.9718 1.0 1232011 ChemDiv1_003025 COc1ccc(cc1)c2nc3cc(NC(=O)c4cc5ccccc5cc4OC)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J12 compound treatment 717704.0 146000.0 0.65 659541.0 108000.0 0.54 0.84 0.9953 1945392 ChemDiv1_003026 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(Br)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J13 compound treatment 730292.0 158000.0 0.71 691085.0 140000.0 0.69 0.9903 0.9999 1623161 ChemDiv1_003027 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J14 compound treatment 739318.0 167000.0 0.75 686072.0 135000.0 0.67 1.0013 0.9984 1971801 ChemDiv1_003028 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J15 compound treatment 750714.0 179000.0 0.8 698753.0 147000.0 0.73 1.0818 0.999 1971802 ChemDiv1_003029 CCOC(=O)C(C)OC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J16 compound treatment 731759.0 160000.0 0.71 670818.0 120000.0 0.59 0.924 0.9956 1971803 ChemDiv1_003030 CCOC(=O)c1c(CN2CCC(CC2)(C(=O)OCC)c3ccccc3)n(c4ccccc4)c5cc(Br)c(O)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J17 compound treatment 762052.0 190000.0 0.85 692767.0 141000.0 0.7 1.0967 0.9954 1971804 ChemDiv1_003031 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC(=O)C)c(OC)c4)C(=O)OCCOc5ccccc5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J18 compound treatment 726218.0 154000.0 0.69 654899.0 104000.0 0.51 0.8507 0.9894 1300591 ChemDiv1_003032 COc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J19 compound treatment 725383.0 153000.0 0.69 664095.0 113000.0 0.56 0.8802 0.9948 1946093 ChemDiv1_003033 CCc1ccc(/C=C\2/SC(=S)N(CCC(=O)O)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J20 compound treatment 694608.0 123000.0 0.55 671163.0 120000.0 0.59 0.8076 0.9992 1971805 ChemDiv1_003034 O=C(CSc1nc2ccccc2o1)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J21 compound treatment 708175.0 136000.0 0.61 675860.0 125000.0 0.62 0.867 1.0 1592777 ChemDiv1_003035 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J22 compound treatment 684214.0 112000.0 0.5 649826.0 98500.0 0.49 0.6999 0.9999 1711243 ChemDiv1_003036 Cn1cnnc1SCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J23 mock treatment 681300.0 109000.0 0.49 649180.0 97900.0 0.48 0.6885 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 J24 mock treatment 495858.0 -76200.0 -0.34 523926.0 -27400.0 -0.14 -0.3373 -0.9183 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K01 compound treatment 542034.0 -30100.0 -0.13 567465.0 16200.0 0.08 -0.0386 -0.2465 1971806 ChemDiv1_003037 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc(c3)[N+](=O)[O-])c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K02 compound treatment 588223.0 16100.0 0.07 595485.0 44200.0 0.22 0.2058 0.893 1971807 ChemDiv1_003038 Fc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K03 compound treatment 608325.0 36200.0 0.16 606822.0 55500.0 0.27 0.3091 0.9683 1672455 ChemDiv1_003039 O=C1CCC(=O)N1c2ccc(cc2)c3nc4scc(c5cccs5)c4c(=O)o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K04 compound treatment 637049.0 64900.0 0.29 599306.0 48000.0 0.24 0.3737 0.995 1971808 ChemDiv1_003040 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K05 compound treatment 664873.0 92800.0 0.42 642945.0 91600.0 0.45 0.6146 0.999 1474583 ChemDiv1_003041 COc1ccc(Cc2nc3c4c5CCCCc5sc4ncn3n2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K06 compound treatment 679679.0 108000.0 0.48 624905.0 73600.0 0.36 0.5983 0.9906 1971809 ChemDiv1_003042 COc1ccc(CCN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(cc4)C(=O)O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K07 compound treatment 684704.0 113000.0 0.5 640631.0 89300.0 0.44 0.6693 0.9979 1971810 ChemDiv1_003043 Fc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)NCCc5ccccc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K08 compound treatment 684520.0 112000.0 0.5 634138.0 82800.0 0.41 0.646 0.9949 1971811 ChemDiv1_003044 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cccc(c3)C(F)(F)F)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K09 compound treatment 692191.0 120000.0 0.54 658519.0 107000.0 0.53 0.7556 1.0 1971812 ChemDiv1_003045 CCOc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K10 compound treatment 727779.0 156000.0 0.7 673346.0 122000.0 0.6 0.9202 0.9975 1971813 ChemDiv1_003046 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K11 compound treatment 723360.0 151000.0 0.68 665639.0 114000.0 0.57 0.8792 0.9961 1971814 ChemDiv1_003047 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccccc3OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K12 compound treatment 678865.0 107000.0 0.48 654219.0 103000.0 0.51 0.6984 0.9995 1711103 ChemDiv1_003048 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(C#N)c2nc(C)cc(C)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K13 compound treatment 703076.0 131000.0 0.59 673811.0 122000.0 0.61 0.8437 0.9999 1971815 ChemDiv1_003049 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)NCCc3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K14 compound treatment 686776.0 115000.0 0.51 643451.0 92100.0 0.46 0.6857 0.9983 1562270 ChemDiv1_003050 CC(=C)CSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K15 compound treatment 721564.0 149000.0 0.67 661776.0 110000.0 0.55 0.86 0.995 1971816 ChemDiv1_003051 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(C)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K16 compound treatment 695118.0 123000.0 0.55 650812.0 99500.0 0.49 0.7379 0.9985 1163881 ChemDiv1_003052 COc1ccc(cc1)n2c(SCC#N)nc3sc4CCCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K17 compound treatment 724402.0 152000.0 0.68 675112.0 124000.0 0.61 0.9157 0.9986 1971817 ChemDiv1_003053 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K18 compound treatment 696267.0 124000.0 0.56 641645.0 90300.0 0.45 0.7094 0.9942 1776162 ChemDiv1_003054 Cc1c(Br)c(nn1CC(=O)N2CCN(Cc3ccccc3)CC2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K19 compound treatment 702549.0 130000.0 0.58 655736.0 104000.0 0.52 0.7787 0.9982 1971818 ChemDiv1_003055 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(F)cc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K20 compound treatment 674400.0 102000.0 0.46 644771.0 93500.0 0.46 0.6512 1.0 1483873 ChemDiv1_003056 CCOc1ccc(cc1)c2cc(C)n3nc(cc3n2)C(=O)Nc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K21 compound treatment 712826.0 141000.0 0.63 662439.0 111000.0 0.55 0.8347 0.9977 1971819 ChemDiv1_003057 COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(F)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K22 compound treatment 678951.0 107000.0 0.48 620800.0 69500.0 0.34 0.5816 0.987 1971820 ChemDiv1_003058 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K23 mock treatment 693240.0 121000.0 0.54 631755.0 80400.0 0.4 0.6652 0.9885 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 K24 mock treatment 472387.0 -99700.0 -0.45 503437.0 -47900.0 -0.24 -0.4833 -0.9562 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L01 compound treatment 549077.0 -23000.0 -0.1 584570.0 33300.0 0.16 0.0436 0.2244 1971821 ChemDiv1_003059 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)Nc4ccc(O)cc4)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L02 compound treatment 629118.0 57000.0 0.26 639400.0 88100.0 0.44 0.489 0.9674 1694032 ChemDiv1_003060 COc1ccccc1C2CC(=NN2C(=O)c3ccco3)c4c(c5ccccc5)c6cc(Br)ccc6[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L03 compound treatment 650870.0 78800.0 0.35 656173.0 105000.0 0.52 0.6166 0.9822 1971822 ChemDiv1_003061 Cc1c(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(=O)n(c6ccccc6)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L04 compound treatment 642885.0 70800.0 0.32 641509.0 90200.0 0.45 0.54 0.9858 1971823 ChemDiv1_003062 COc1ccc(CNC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L05 compound treatment 655366.0 83300.0 0.37 659023.0 108000.0 0.53 0.6408 0.9846 1971824 ChemDiv1_003063 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCn3ccnc3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L06 compound treatment 658830.0 86700.0 0.39 632799.0 81500.0 0.4 0.5599 0.9998 1147098 ChemDiv1_003064 Cc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L07 compound treatment 713079.0 141000.0 0.63 658839.0 108000.0 0.53 0.8229 0.9964 1943146 ChemDiv1_003065 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L08 compound treatment 695920.0 124000.0 0.55 641300.0 90000.0 0.45 0.7071 0.9942 1522461 ChemDiv1_003066 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L09 compound treatment 702278.0 130000.0 0.58 663492.0 112000.0 0.56 0.805 0.9997 1971825 ChemDiv1_003067 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCSCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L10 compound treatment 719149.0 147000.0 0.66 663848.0 113000.0 0.56 0.8596 0.9966 1971826 ChemDiv1_003068 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L11 compound treatment 725028.0 153000.0 0.68 689480.0 138000.0 0.68 0.968 1.0 1780660 ChemDiv1_003069 Oc1cc(NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])ccc1c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L12 compound treatment 704318.0 132000.0 0.59 665657.0 114000.0 0.57 0.819 0.9998 1207581 ChemDiv1_003070 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L13 compound treatment 704010.0 132000.0 0.59 652574.0 101000.0 0.5 0.7722 0.9967 1971827 ChemDiv1_003071 CN1C(=C(C(NC1=O)c2ccc(Br)s2)C(=O)OCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L14 compound treatment 712432.0 140000.0 0.63 668095.0 117000.0 0.58 0.8532 0.9992 1971828 ChemDiv1_003072 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L15 compound treatment 724419.0 152000.0 0.68 678097.0 127000.0 0.63 0.9262 0.9992 1568329 ChemDiv1_003073 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L16 compound treatment 732509.0 160000.0 0.72 677093.0 126000.0 0.62 0.9483 0.9975 1570991 ChemDiv1_003074 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(C)c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L17 compound treatment 718228.0 146000.0 0.65 695549.0 144000.0 0.71 0.9678 0.999 1496075 ChemDiv1_003075 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC)c(OC)c4)C(=O)OCC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L18 compound treatment 704062.0 132000.0 0.59 651472.0 100000.0 0.5 0.7685 0.9962 1305028 ChemDiv1_003076 COc1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L19 compound treatment 713791.0 142000.0 0.63 661713.0 110000.0 0.55 0.8352 0.9973 1971829 ChemDiv1_003077 COc1ccccc1C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L20 compound treatment 683937.0 112000.0 0.5 661431.0 110000.0 0.55 0.7397 0.9991 1971830 ChemDiv1_003078 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(C6CCCCC6)C5=O)C(=O)N1C7CCCCC7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L21 compound treatment 731288.0 159000.0 0.71 663086.0 112000.0 0.55 0.8954 0.9922 1971831 ChemDiv1_003079 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L22 compound treatment 695950.0 124000.0 0.55 636884.0 85600.0 0.42 0.6918 0.9912 1971832 ChemDiv1_003080 CC1(CN2CC3(C)CN(C1)C24C(=O)Nc5ccccc54)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L23 mock treatment 693081.0 121000.0 0.54 651318.0 100000.0 0.5 0.7332 0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 L24 mock treatment 475799.0 -96300.0 -0.43 546143.0 -5170.0 -0.03 -0.3229 -0.7478 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M01 compound treatment 516430.0 -55700.0 -0.25 566040.0 14700.0 0.07 -0.1246 -0.48 1971833 ChemDiv1_003081 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3cccc(Cl)c3)c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M02 compound treatment 547068.0 -25000.0 -0.11 594527.0 43200.0 0.21 0.0721 0.2985 1971834 ChemDiv1_003082 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)Nc4ccc(OC)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M03 compound treatment 624299.0 52200.0 0.23 651913.0 101000.0 0.5 0.5176 0.9404 1971835 ChemDiv1_003083 COc1ccc(/C=C/c2nc3scc(c4cccs4)c3c(=O)o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M04 compound treatment 611715.0 39600.0 0.18 622952.0 71600.0 0.35 0.3763 0.9486 1971836 ChemDiv1_003084 COc1ccccc1NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccccc4)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M05 compound treatment 657062.0 85000.0 0.38 640823.0 89500.0 0.44 0.5825 0.9971 1262178 ChemDiv1_003085 COc1ccc(Cc2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M06 compound treatment 638338.0 66200.0 0.3 626224.0 74900.0 0.37 0.4721 0.9938 1971837 ChemDiv1_003086 CN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M07 compound treatment 670887.0 98800.0 0.44 653652.0 102000.0 0.51 0.6712 0.9977 1971838 ChemDiv1_003087 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc(OC)cc3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M08 compound treatment 676832.0 105000.0 0.47 637655.0 86300.0 0.43 0.6339 0.999 1971839 ChemDiv1_003088 OC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M09 compound treatment 688461.0 116000.0 0.52 647941.0 96600.0 0.48 0.7068 0.9991 1971840 ChemDiv1_003089 COc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)NCCc5ccccc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M10 compound treatment 672238.0 100000.0 0.45 641642.0 90300.0 0.45 0.6334 1.0 1971841 ChemDiv1_003090 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccccc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M11 compound treatment 740447.0 168000.0 0.75 652499.0 101000.0 0.5 0.8873 0.9804 1971842 ChemDiv1_003091 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3ccc(OCC)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M12 compound treatment 677750.0 106000.0 0.47 644561.0 93200.0 0.46 0.661 0.9999 1714667 ChemDiv1_003092 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M13 compound treatment 707910.0 136000.0 0.61 655785.0 104000.0 0.52 0.7958 0.9968 1971843 ChemDiv1_003093 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)NCCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M14 compound treatment 703317.0 131000.0 0.59 663072.0 112000.0 0.55 0.8068 0.9996 1413010 ChemDiv1_003094 COC(=O)c1ccc(o1)c2sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M15 compound treatment 734998.0 163000.0 0.73 669677.0 118000.0 0.59 0.9302 0.9942 1971844 ChemDiv1_003095 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(C)c(Cl)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M16 compound treatment 693066.0 121000.0 0.54 643147.0 91800.0 0.45 0.7046 0.9962 1971845 ChemDiv1_003096 CCNc1nc(NCC)nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M17 compound treatment 696439.0 124000.0 0.56 658794.0 107000.0 0.53 0.77 0.9998 1971846 ChemDiv1_003097 COC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(Cl)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M18 compound treatment 688373.0 116000.0 0.52 640186.0 88900.0 0.44 0.6793 0.9965 1971847 ChemDiv1_003098 Cc1cc(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M19 compound treatment 704174.0 132000.0 0.59 663000.0 112000.0 0.55 0.8093 0.9995 1971848 ChemDiv1_003099 CCOc1ccc(/N=C/2\SC(CC(=O)N2Cc3ccc4OCOc4c3)C(=O)Nc5ccc(cc5)C(=O)OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M20 compound treatment 657080.0 85000.0 0.38 620329.0 69000.0 0.34 0.5107 0.9986 1253275 ChemDiv1_003100 CCOc1ccc(cc1)c2cc(C)n3nc(cc3n2)C(=O)Nc4cc(OC)c(Cl)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M21 compound treatment 712994.0 141000.0 0.63 667200.0 116000.0 0.57 0.8519 0.9989 1971849 ChemDiv1_003101 OC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(Cl)cc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M22 compound treatment 680734.0 109000.0 0.49 617309.0 66000.0 0.33 0.575 0.9813 1971850 ChemDiv1_003102 COc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)Nc4ccc(cc4)C(=O)C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M23 mock treatment 686342.0 114000.0 0.51 628398.0 77100.0 0.38 0.6316 0.9897 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 M24 mock treatment 562172.0 -9930.0 -0.04 335202.0 -216000.0 -1.07 -0.7884 -0.7358 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N01 compound treatment 514574.0 -57500.0 -0.26 587858.0 36500.0 0.18 -0.0541 -0.1718 1971851 ChemDiv1_003103 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)NCc4cccs4)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N02 compound treatment 560962.0 -11100.0 -0.05 627788.0 76500.0 0.38 0.2326 0.6088 1971852 ChemDiv1_003104 FC(F)(F)c1ccccc1NC(=O)CSc2nc3ccccc3[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N03 compound treatment 580683.0 8580.0 0.04 642538.0 91200.0 0.45 0.3467 0.7644 1971853 ChemDiv1_003105 FC(F)(F)c1cc(nc2cc(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N04 compound treatment 596202.0 24100.0 0.11 618250.0 66900.0 0.33 0.3107 0.8912 1650975 ChemDiv1_003106 CCOc1ccc2nc(SCC(=O)Nc3ccccc3C(=O)N)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N05 compound treatment 621160.0 49100.0 0.22 640818.0 89500.0 0.44 0.4688 0.9475 1971854 ChemDiv1_003107 COc1ccc(CNC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N06 compound treatment 609236.0 37100.0 0.17 641317.0 90000.0 0.45 0.4328 0.9096 1328501 ChemDiv1_003108 CCOc1ccc2nc(NC(=O)c3ccc4OCCOc4c3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N07 compound treatment 682038.0 110000.0 0.49 662008.0 111000.0 0.55 0.7357 0.9985 1943244 ChemDiv1_003109 CN1CCN(CC1)C(=O)c2nn3c(cc(nc3c2Cl)c4ccc(Cl)cc4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N08 compound treatment 694838.0 123000.0 0.55 656704.0 105000.0 0.52 0.7577 0.9997 1382091 ChemDiv1_003110 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccc(OC)c(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N09 compound treatment 716878.0 145000.0 0.65 673445.0 122000.0 0.61 0.8861 0.9994 1971855 ChemDiv1_003111 COc1ccc(cc1OC)c2cc(n3nc(C(=O)N4CCCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N10 compound treatment 678526.0 106000.0 0.48 650654.0 99300.0 0.49 0.6848 0.9999 1945434 ChemDiv1_003112 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N11 compound treatment 700376.0 128000.0 0.57 670226.0 119000.0 0.59 0.8226 0.9999 1971856 ChemDiv1_003113 [O-][N+](=O)c1ccc(COc2ccc(Br)cc2/C=C/3\NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N12 compound treatment 684399.0 112000.0 0.5 635529.0 84200.0 0.42 0.6504 0.9957 1194306 ChemDiv1_003114 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2cccs2)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N13 compound treatment 726546.0 154000.0 0.69 672070.0 121000.0 0.6 0.9118 0.9974 1204119 ChemDiv1_003115 COc1cc(cc(OC)c1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N14 compound treatment 709253.0 137000.0 0.61 649245.0 97900.0 0.49 0.7772 0.9932 1971857 ChemDiv1_003116 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N15 compound treatment 724517.0 152000.0 0.68 670920.0 120000.0 0.59 0.9014 0.9975 1784056 ChemDiv1_003117 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N16 compound treatment 700269.0 128000.0 0.57 631747.0 80400.0 0.4 0.6874 0.9841 1137308 ChemDiv1_003118 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(C)c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N17 compound treatment 701385.0 129000.0 0.58 656852.0 106000.0 0.52 0.7789 0.9987 1864258 ChemDiv1_003119 COC(=O)c1c(NC(=O)CCN2C(=O)c3cccc([N+](=O)[O-])c3C2=O)sc4CC(C)CCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N18 compound treatment 677322.0 105000.0 0.47 657964.0 107000.0 0.53 0.7066 0.9984 1566688 ChemDiv1_003120 C(Nc1nc(nc(n1)N2CCOCC2)N3CCOCC3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N19 compound treatment 750305.0 178000.0 0.8 680095.0 129000.0 0.64 1.0152 0.9939 1646510 ChemDiv1_003121 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N20 compound treatment 683685.0 112000.0 0.5 643322.0 92000.0 0.46 0.6755 0.999 1971858 ChemDiv1_003122 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(C5=O)c6ccccn6)C(=O)N1c7ccccn7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N21 compound treatment 693998.0 122000.0 0.55 646483.0 95200.0 0.47 0.7192 0.9974 1971859 ChemDiv1_003123 COc1ccccc1C2CC(=NN2C(=O)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N22 compound treatment 675548.0 103000.0 0.46 617479.0 66200.0 0.33 0.5592 0.9857 1971860 ChemDiv1_003124 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N23 mock treatment 684137.0 112000.0 0.5 629307.0 78000.0 0.39 0.6278 0.9917 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 N24 mock treatment 402570.0 -170000.0 -0.76 417854.0 -133000.0 -0.66 -1.0041 -0.9976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O01 compound treatment 497313.0 -74800.0 -0.33 574234.0 22900.0 0.11 -0.1564 -0.4425 1616099 ChemDiv1_003125 CCCCn1c(C)c(C(=O)OCC)c2cc(OC(=O)c3ccccc3F)c4ccccc4c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O02 compound treatment 483798.0 -88300.0 -0.4 561429.0 10100.0 0.05 -0.2441 -0.6126 1971861 ChemDiv1_003126 COc1ccccc1NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O03 compound treatment 531430.0 -40700.0 -0.18 587403.0 36100.0 0.18 -0.0023 -0.0091 1944231 ChemDiv1_003127 COc1ccc(/C=C/c2nc3sc4CCCCc4c3c(=O)o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O04 compound treatment 546437.0 -25700.0 -0.11 593382.0 42100.0 0.21 0.0661 0.2778 1971862 ChemDiv1_003128 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O05 compound treatment 607296.0 35200.0 0.16 611754.0 60400.0 0.3 0.3231 0.955 1209043 ChemDiv1_003129 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc4OCOc4cc3Br)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O06 compound treatment 578490.0 6390.0 0.03 601619.0 50300.0 0.25 0.1964 0.7831 1971863 ChemDiv1_003130 COC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc4OCOc4c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O07 compound treatment 616476.0 44400.0 0.2 612691.0 61400.0 0.3 0.3554 0.9787 1971864 ChemDiv1_003131 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O08 compound treatment 647710.0 75600.0 0.34 620233.0 68900.0 0.34 0.4807 1.0 1971865 ChemDiv1_003132 CCOc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(cc3)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O09 compound treatment 656512.0 84400.0 0.38 623754.0 72400.0 0.36 0.5209 0.9997 1971866 ChemDiv1_003133 CCOc1cccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccc(OC)cc5)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O10 compound treatment 644547.0 72400.0 0.32 592377.0 41100.0 0.2 0.3731 0.9748 1971867 ChemDiv1_003134 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O11 compound treatment 675226.0 103000.0 0.46 620880.0 69600.0 0.34 0.5701 0.9896 1971868 ChemDiv1_003135 CCOC(=O)c1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)NCCc3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O12 compound treatment 645643.0 73500.0 0.33 607356.0 56000.0 0.28 0.4291 0.9964 1570697 ChemDiv1_003136 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O13 compound treatment 658839.0 86700.0 0.39 627658.0 76300.0 0.38 0.542 0.9999 1971869 ChemDiv1_003137 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C)/C(=N\c3ccc(OC)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O14 compound treatment 646785.0 74700.0 0.33 609028.0 57700.0 0.29 0.4386 0.997 1186933 ChemDiv1_003138 CN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O15 compound treatment 705786.0 134000.0 0.6 637524.0 86200.0 0.43 0.7251 0.9863 1971870 ChemDiv1_003139 CCOc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)Nc3cccc(OCC)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O16 compound treatment 646391.0 74300.0 0.33 601926.0 50600.0 0.25 0.4124 0.9903 1971871 ChemDiv1_003140 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccc(Cl)c(Cl)c3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O17 compound treatment 676500.0 104000.0 0.47 637963.0 86700.0 0.43 0.634 0.9991 1971872 ChemDiv1_003141 CN/1C(=O)CC(S\C1=N\c2cccc(c2)C(F)(F)F)C(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O18 compound treatment 624149.0 52000.0 0.23 610779.0 59500.0 0.29 0.373 0.9932 1971873 ChemDiv1_003142 COc1cc(NC(=O)Cn2nc(c(Br)c2C)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O19 compound treatment 667809.0 95700.0 0.43 636977.0 85700.0 0.42 0.603 1.0 1971874 ChemDiv1_003143 CCOc1ccc(/N=C\2/SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O20 compound treatment 673182.0 101000.0 0.45 606963.0 55700.0 0.28 0.5149 0.9718 1971875 ChemDiv1_003144 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)NCc4ccco4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O21 compound treatment 690121.0 118000.0 0.53 626419.0 75100.0 0.37 0.6366 0.9853 1971876 ChemDiv1_003145 COc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccc(F)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O22 compound treatment 646955.0 74900.0 0.34 589903.0 38600.0 0.19 0.3721 0.9646 1971877 ChemDiv1_003146 COc1ccc(CNC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(OC)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O23 mock treatment 646023.0 73900.0 0.33 591763.0 40500.0 0.2 0.3757 0.9711 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 O24 mock treatment 546681.0 -25400.0 -0.11 427517.0 -124000.0 -0.61 -0.5141 -0.8243 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P01 compound treatment 488216.0 -83900.0 -0.38 563390.0 12100.0 0.06 -0.2232 -0.587 1971878 ChemDiv1_003147 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)N4CCN(Cc5ccccc5)CC4)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P02 compound treatment 496423.0 -75700.0 -0.34 569818.0 18500.0 0.09 -0.1747 -0.4979 1516943 ChemDiv1_003148 COc1ccc2nc(NC(=O)CSc3nc4ccccc4[nH]3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P03 compound treatment 580319.0 8210.0 0.04 588676.0 37400.0 0.19 0.1569 0.8313 1971879 ChemDiv1_003149 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)NCCCn5ccnc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P04 compound treatment 569384.0 -2720.0 -0.01 593273.0 42000.0 0.21 0.1384 0.6645 1374030 ChemDiv1_003150 CCOc1ccc2nc(SCC(=O)Nc3cccc(c3)C(=O)O)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P05 compound treatment 591023.0 18900.0 0.08 590033.0 38700.0 0.19 0.1955 0.9325 1971880 ChemDiv1_003151 Cc1c(NC(=O)c2nn3c(cc(nc3c2Cl)c4ccco4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P06 compound treatment 617013.0 44900.0 0.2 595180.0 43900.0 0.22 0.2958 0.9992 1615130 ChemDiv1_003152 O=C(Nc1ccc2c(c1)oc3ccccc32)c4ccc5OCCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P07 compound treatment 638398.0 66300.0 0.3 600877.0 49600.0 0.25 0.3835 0.9956 1971881 ChemDiv1_003153 FC(F)(F)c1cc(nc2c(Cl)c(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P08 compound treatment 594190.0 22100.0 0.1 625664.0 74400.0 0.37 0.3304 0.8662 1971882 ChemDiv1_003154 OC(=O)c1ccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P09 compound treatment 622053.0 49900.0 0.22 597646.0 46300.0 0.23 0.3204 0.9999 1971883 ChemDiv1_003155 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCC4CCCO4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P10 compound treatment 663414.0 91300.0 0.41 622514.0 71200.0 0.35 0.5384 0.9973 1945432 ChemDiv1_003156 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(Br)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P11 compound treatment 637722.0 65600.0 0.29 601027.0 49700.0 0.25 0.3818 0.9962 1971884 ChemDiv1_003157 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P12 compound treatment 670109.0 98000.0 0.44 618028.0 66700.0 0.33 0.5439 0.9902 1784060 ChemDiv1_003158 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P13 compound treatment 672496.0 100000.0 0.45 612239.0 60900.0 0.3 0.5312 0.9812 1593304 ChemDiv1_003159 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3ccc(cc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P14 compound treatment 678364.0 106000.0 0.48 614928.0 63600.0 0.32 0.5592 0.98 1971885 ChemDiv1_003160 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(CC)CC)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P15 compound treatment 656016.0 83900.0 0.38 611681.0 60400.0 0.3 0.4771 0.9936 1971886 ChemDiv1_003161 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P16 compound treatment 656436.0 84300.0 0.38 609968.0 58700.0 0.29 0.4724 0.9916 1739355 ChemDiv1_003162 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4ccc(O)c(CN(C)C)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P17 compound treatment 663702.0 91600.0 0.41 626484.0 75200.0 0.37 0.5532 0.9988 1460769 ChemDiv1_003163 COC(=O)C1CCc2sc(NC(=O)CCN3C(=O)c4ccccc4C3=O)c(C(=O)OC)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P18 compound treatment 633868.0 61800.0 0.28 600533.0 49200.0 0.24 0.3679 0.998 1733388 ChemDiv1_003164 COc1ccc(Nc2nc(Cl)nc(NC3CCCC3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P19 compound treatment 604969.0 32900.0 0.15 617380.0 66100.0 0.33 0.3355 0.9348 1947343 ChemDiv1_003165 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P20 compound treatment 646244.0 74100.0 0.33 607950.0 56600.0 0.28 0.4331 0.9965 1946374 ChemDiv1_003166 CC1(C)Cc2c(CO1)sc3nc(oc(=O)c23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P21 compound treatment 669505.0 97400.0 0.44 612481.0 61200.0 0.3 0.5226 0.9842 1923870 ChemDiv1_003167 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P22 compound treatment 643061.0 71000.0 0.32 582524.0 31200.0 0.15 0.3339 0.9453 1971887 ChemDiv1_003168 COc1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P23 mock treatment 650054.0 77900.0 0.35 595529.0 44200.0 0.22 0.4016 0.9748 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.595 P24 mock treatment 396016.0 -176000.0 -0.79 226504.0 -325000.0 -1.61 -1.6951 -0.9461 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A01 compound treatment 566432.0 54300.0 0.24 549405.0 -23900.0 -0.12 0.088 0.3256 1971888 ChemDiv1_003169 CN(C)c1ccc(cc1[N+](=O)[O-])C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A02 compound treatment 529109.0 16900.0 0.08 551993.0 -21300.0 -0.11 -0.0211 -0.1622 1971889 ChemDiv1_003170 Brc1ccc2NC(=O)/C(=C\3/S/C(=N\S(=O)(=O)c4ccccc4)/NC3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A03 compound treatment 564032.0 51900.0 0.23 569983.0 -3330.0 -0.02 0.1525 0.6552 1320513 ChemDiv1_003171 COc1ccc(cc1)c2cc(C(=O)N3CCN(CC3)c4ccccc4OC)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A04 compound treatment 548353.0 36200.0 0.16 571181.0 -2130.0 -0.01 0.107 0.6595 1971890 ChemDiv1_003172 O=c1c2ccccc2c(=O)c3c4[nH]c5ccccc5oc4cc(NCc6ccccc6)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A05 compound treatment 577983.0 65800.0 0.29 595507.0 22200.0 0.11 0.286 0.9097 1579877 ChemDiv1_003173 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(OC)c3OC)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A06 compound treatment 581253.0 69100.0 0.31 596799.0 23500.0 0.12 0.3009 0.9108 1971891 ChemDiv1_003174 COc1ccc2nc(Nc3nc(O)cc(n3)c4ccccc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A07 compound treatment 589125.0 76900.0 0.34 635049.0 61700.0 0.31 0.4598 0.9982 1946104 ChemDiv1_003175 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCc3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A08 compound treatment 612484.0 100000.0 0.45 622973.0 49700.0 0.25 0.4914 0.9599 1663451 ChemDiv1_003176 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A09 compound treatment 635090.0 123000.0 0.55 613134.0 39800.0 0.2 0.5285 0.9043 1971892 ChemDiv1_003177 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(cc3)C(C)(C)C)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A10 compound treatment 612345.0 100000.0 0.45 619549.0 46200.0 0.23 0.479 0.9514 1571603 ChemDiv1_003178 CC1=C(C(NC(=O)N1)c2cccc(Oc3ccccc3)c2)C(=O)OCc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A11 compound treatment 615081.0 103000.0 0.46 651401.0 78100.0 0.39 0.5992 0.9962 1971893 ChemDiv1_003179 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)(C)C)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A12 compound treatment 594692.0 82500.0 0.37 632832.0 59500.0 0.29 0.4697 0.9938 1923306 ChemDiv1_003180 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A13 compound treatment 597976.0 85800.0 0.38 653670.0 80400.0 0.4 0.5531 0.9998 1971894 ChemDiv1_003181 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)OC)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A14 compound treatment 615097.0 103000.0 0.46 628164.0 54800.0 0.27 0.5179 0.9683 1924022 ChemDiv1_003182 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A15 compound treatment 623944.0 112000.0 0.5 633406.0 60100.0 0.3 0.5643 0.9692 1945599 ChemDiv1_003183 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A16 compound treatment 599607.0 87400.0 0.39 624335.0 51000.0 0.25 0.4555 0.9776 1971895 ChemDiv1_003184 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A17 compound treatment 602822.0 90600.0 0.41 608940.0 35600.0 0.18 0.4117 0.9305 1945867 ChemDiv1_003185 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A18 compound treatment 613041.0 101000.0 0.45 618877.0 45600.0 0.23 0.4789 0.9487 1943173 ChemDiv1_003186 [O-][N+](=O)c1ccc(OCCOc2cccc(C=C3C(=O)NC(=O)NC3=O)c2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A19 compound treatment 562489.0 50300.0 0.23 593623.0 20300.0 0.1 0.2304 0.934 1309298 ChemDiv1_003187 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A20 compound treatment 582608.0 70400.0 0.32 586065.0 12700.0 0.06 0.2676 0.8322 1971896 ChemDiv1_003188 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCSc3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A21 compound treatment 570384.0 58200.0 0.26 582953.0 9640.0 0.05 0.218 0.823 1971897 ChemDiv1_003189 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Br)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A22 compound treatment 545085.0 32900.0 0.15 554011.0 -19300.0 -0.1 0.0365 0.2081 1971898 ChemDiv1_003190 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCSc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A23 mock treatment 545199.0 33000.0 0.15 547680.0 -25600.0 -0.13 0.0147 0.0756 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 A24 mock treatment 480678.0 -31500.0 -0.14 527201.0 -46100.0 -0.23 -0.2612 -0.9731 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B01 compound treatment 601668.0 89500.0 0.4 565314.0 -8000.0 -0.04 0.2552 0.634 1603156 ChemDiv1_003191 CC(=O)Nc1ccc(cc1)C(=O)CSc2nc(O)c3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B02 compound treatment 606764.0 94600.0 0.42 593543.0 20200.0 0.1 0.3703 0.8509 1491654 ChemDiv1_003192 COC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B03 compound treatment 652481.0 140000.0 0.63 629940.0 56600.0 0.28 0.6425 0.934 1260827 ChemDiv1_003193 Cc1ccc2nc(oc2c1)c3cc(NC(=O)c4cccc(OCc5ccccc5)c4)ccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B04 compound treatment 656807.0 145000.0 0.65 641305.0 68000.0 0.34 0.696 0.9536 1164076 ChemDiv1_003194 OC(COc1ccccc1C(=O)Nc2ccccc2)CN3C(=O)c4ccccc4S3(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B05 compound treatment 679626.0 167000.0 0.75 656735.0 83400.0 0.41 0.8222 0.9606 1971899 ChemDiv1_003195 COc1ccccc1OCCSc2nc3ccccc3n2CC(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B06 compound treatment 651683.0 140000.0 0.62 637785.0 64500.0 0.32 0.6674 0.9515 1971900 ChemDiv1_003196 CCN(CC)CCCNc1nc(nc2ccccc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B07 compound treatment 712678.0 201000.0 0.9 699467.0 126000.0 0.62 1.0765 0.9843 1971901 ChemDiv1_003197 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B08 compound treatment 686932.0 175000.0 0.78 685137.0 112000.0 0.55 0.9448 0.9857 1547367 ChemDiv1_003198 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B09 compound treatment 694303.0 182000.0 0.82 718341.0 145000.0 0.72 1.0845 0.998 1971902 ChemDiv1_003199 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B10 compound treatment 683429.0 171000.0 0.77 702523.0 129000.0 0.64 0.9947 0.996 1971903 ChemDiv1_003200 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B11 compound treatment 684292.0 172000.0 0.77 719106.0 146000.0 0.72 1.0555 0.9995 1784075 ChemDiv1_003201 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B12 compound treatment 663560.0 151000.0 0.68 691447.0 118000.0 0.59 0.893 0.9973 1624483 ChemDiv1_003202 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B13 compound treatment 670524.0 158000.0 0.71 713459.0 140000.0 0.69 0.9921 0.9999 1971904 ChemDiv1_003203 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B14 compound treatment 675812.0 164000.0 0.73 697636.0 124000.0 0.62 0.9534 0.9963 1465862 ChemDiv1_003204 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccc(Cl)cc5c4=O)C(=O)CC(C)(C)C3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B15 compound treatment 693530.0 181000.0 0.81 717187.0 144000.0 0.71 1.078 0.9979 1255871 ChemDiv1_003205 COC(=O)CN(c1nc(C)c(Cl)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B16 compound treatment 650663.0 138000.0 0.62 698303.0 125000.0 0.62 0.8762 1.0 1419891 ChemDiv1_003206 CN1C2CCC1C=C(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B17 compound treatment 679563.0 167000.0 0.75 711706.0 138000.0 0.69 1.0146 0.999 1368941 ChemDiv1_003207 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(n2)n3nc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B18 compound treatment 635952.0 124000.0 0.55 679616.0 106000.0 0.53 0.7641 0.9997 1971905 ChemDiv1_003208 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B19 compound treatment 644560.0 132000.0 0.59 694693.0 121000.0 0.6 0.8442 1.0 1971906 ChemDiv1_003209 CC(C)Nc1nc(NC(C)C)nc(OCCOC(=O)c2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B20 compound treatment 624812.0 113000.0 0.5 653373.0 80100.0 0.4 0.637 0.9929 1688615 ChemDiv1_003210 COc1ccc(cc1OC)C(=O)Nc2ccc3oc(nc3c2)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B21 compound treatment 654108.0 142000.0 0.64 651252.0 77900.0 0.39 0.7223 0.9715 1971907 ChemDiv1_003211 CCOc1nc(SCCOc2ccc(C)cc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B22 compound treatment 598384.0 86200.0 0.39 632953.0 59600.0 0.3 0.4818 0.9913 1543048 ChemDiv1_003212 COc1cc(ccc1OC(=O)CNc2ccc3OCOc3c2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B23 mock treatment 613446.0 101000.0 0.45 627706.0 54400.0 0.27 0.5111 0.9691 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 B24 mock treatment 472502.0 -39700.0 -0.18 495408.0 -77900.0 -0.39 -0.3985 -0.9379 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C01 compound treatment 564676.0 52500.0 0.24 552137.0 -21200.0 -0.1 0.092 0.3574 1971908 ChemDiv1_003213 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C02 compound treatment 603127.0 91000.0 0.41 591357.0 18000.0 0.09 0.3511 0.8423 1572581 ChemDiv1_003214 Brc1ccc(NC(=O)CSC2=C(C#N)C3(CCC(CC3)c4ccccc4)C(C#N)C(=O)N2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C03 compound treatment 644401.0 132000.0 0.59 644048.0 70700.0 0.35 0.6663 0.9687 1946149 ChemDiv1_003215 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C04 compound treatment 637330.0 125000.0 0.56 634936.0 61600.0 0.31 0.612 0.9592 1971909 ChemDiv1_003216 Clc1ccc2[nH]c3c(cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C05 compound treatment 714335.0 202000.0 0.9 711811.0 138000.0 0.69 1.125 0.9907 1145067 ChemDiv1_003217 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)c(OC)c3)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C06 compound treatment 663095.0 151000.0 0.68 639642.0 66300.0 0.33 0.71 0.9452 1574917 ChemDiv1_003218 COc1cc(cc(OC)c1OC)C(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C07 compound treatment 682708.0 171000.0 0.76 694363.0 121000.0 0.6 0.9638 0.9929 1946274 ChemDiv1_003219 COc1cc(/C=C/2\C(=O)NC(=O)N(C)C2=O)ccc1OCc3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C08 compound treatment 685079.0 173000.0 0.77 655223.0 81900.0 0.41 0.8342 0.9546 1675008 ChemDiv1_003220 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C09 compound treatment 694103.0 182000.0 0.81 703784.0 130000.0 0.65 1.0329 0.9934 1945717 ChemDiv1_003221 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C10 compound treatment 650799.0 139000.0 0.62 657761.0 84400.0 0.42 0.7346 0.9816 1497488 ChemDiv1_003222 CC1=C(C(NC(=O)N1)c2cccc(Oc3ccccc3)c2)C(=O)OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C11 compound treatment 699848.0 188000.0 0.84 720766.0 147000.0 0.73 1.1105 0.9976 1946172 ChemDiv1_003223 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C12 compound treatment 663296.0 151000.0 0.68 711281.0 138000.0 0.68 0.9616 1.0 1971910 ChemDiv1_003224 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C13 compound treatment 672005.0 160000.0 0.72 732098.0 159000.0 0.79 1.0621 0.9989 1946427 ChemDiv1_003225 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(cc3)C(C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C14 compound treatment 662736.0 151000.0 0.67 683622.0 110000.0 0.55 0.863 0.9946 1971911 ChemDiv1_003226 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C15 compound treatment 688172.0 176000.0 0.79 723822.0 151000.0 0.75 1.0843 0.9996 1971912 ChemDiv1_003227 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)OC)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C16 compound treatment 649397.0 137000.0 0.61 688457.0 115000.0 0.57 0.8377 0.9993 1971913 ChemDiv1_003228 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3cccc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C17 compound treatment 666094.0 154000.0 0.69 695274.0 122000.0 0.6 0.9144 0.9979 1971914 ChemDiv1_003229 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C18 compound treatment 635170.0 123000.0 0.55 682105.0 109000.0 0.54 0.7704 0.9999 1943237 ChemDiv1_003230 CN1C(=O)N(C)C(=O)C(=Cc2cccc(OCCOc3ccc(cc3)[N+](=O)[O-])c2)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C19 compound treatment 626581.0 114000.0 0.51 651797.0 78500.0 0.39 0.637 0.9908 1157426 ChemDiv1_003231 COc1cc(cc(OC)c1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C20 compound treatment 622566.0 110000.0 0.49 652944.0 79600.0 0.39 0.6283 0.9938 1971915 ChemDiv1_003232 CCOC(=O)CSCCOc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C21 compound treatment 601450.0 89300.0 0.4 657111.0 83800.0 0.42 0.5761 0.9998 1710015 ChemDiv1_003233 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C22 compound treatment 603191.0 91000.0 0.41 621220.0 47900.0 0.24 0.4559 0.9669 1971916 ChemDiv1_003234 CCOC(=O)CSCCOc1ccc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C23 mock treatment 604018.0 91800.0 0.41 617668.0 44400.0 0.22 0.4461 0.9569 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 C24 mock treatment 464001.0 -48200.0 -0.22 510001.0 -63300.0 -0.31 -0.3743 -0.9833 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D01 compound treatment 626424.0 114000.0 0.51 586690.0 13400.0 0.07 0.4085 0.7921 1971917 ChemDiv1_003235 COc1ccc(cc1OC)C(=O)CSc2nc(O)c3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D02 compound treatment 624335.0 112000.0 0.5 611065.0 37700.0 0.19 0.4872 0.9094 1245752 ChemDiv1_003236 CCNc1nc(NCC)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D03 compound treatment 614059.0 102000.0 0.46 602468.0 29200.0 0.14 0.4246 0.8876 1683341 ChemDiv1_003237 O=C(Nc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D04 compound treatment 648402.0 136000.0 0.61 649594.0 76300.0 0.38 0.6984 0.9735 1490278 ChemDiv1_003238 OC(CNS(=O)(=O)c1ccccc1C(=O)N2CCOCC2)COc3ccc(cc3)N4C(=O)C5CC=CCC5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D05 compound treatment 679319.0 167000.0 0.75 678426.0 105000.0 0.52 0.8972 0.9843 1971918 ChemDiv1_003239 COc1ccccc1OCCSc2nc3ccccc3n2CC(O)CO 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D06 compound treatment 630685.0 119000.0 0.53 643477.0 70200.0 0.35 0.6209 0.979 1159575 ChemDiv1_003240 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D07 compound treatment 707292.0 195000.0 0.87 681748.0 108000.0 0.54 0.9974 0.9727 1441303 ChemDiv1_003241 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OCC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D08 compound treatment 699625.0 187000.0 0.84 654513.0 81200.0 0.4 0.8778 0.9433 1971919 ChemDiv1_003242 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D09 compound treatment 725688.0 214000.0 0.96 682409.0 109000.0 0.54 1.058 0.9636 1193799 ChemDiv1_003243 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D10 compound treatment 721337.0 209000.0 0.94 694218.0 121000.0 0.6 1.0856 0.9767 1971920 ChemDiv1_003244 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D11 compound treatment 722380.0 210000.0 0.94 727028.0 154000.0 0.76 1.2038 0.9945 1384080 ChemDiv1_003245 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D12 compound treatment 705327.0 193000.0 0.86 685070.0 112000.0 0.55 1.0028 0.9768 1971921 ChemDiv1_003246 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D13 compound treatment 688452.0 176000.0 0.79 726634.0 153000.0 0.76 1.095 0.9998 1783908 ChemDiv1_003247 COc1ccc(CCN2C(SCC2=O)c3ccc(cc3)[N+](=O)[O-])cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D14 compound treatment 660305.0 148000.0 0.66 657640.0 84300.0 0.42 0.7642 0.9752 1971922 ChemDiv1_003248 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D15 compound treatment 692737.0 181000.0 0.81 750235.0 177000.0 0.88 1.1913 0.9992 1142854 ChemDiv1_003249 CCNc1nc(NC(C)C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D16 compound treatment 688201.0 176000.0 0.79 725694.0 152000.0 0.75 1.0909 0.9998 1736301 ChemDiv1_003250 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D17 compound treatment 703933.0 192000.0 0.86 747764.0 174000.0 0.86 1.218 1.0 1163540 ChemDiv1_003251 COc1nc(NS(=O)(=O)c2ccc(C)cc2)nc(C)c1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D18 compound treatment 628524.0 116000.0 0.52 636460.0 63100.0 0.31 0.5895 0.9702 1971923 ChemDiv1_003252 CN1C(=C(C(NC1=O)c2cccc(c2)C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D19 compound treatment 657286.0 145000.0 0.65 700076.0 127000.0 0.63 0.9033 0.9999 1971924 ChemDiv1_003253 CN(C)c1nc(SCCOC(=O)Nc2ccccc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D20 compound treatment 647515.0 135000.0 0.61 681368.0 108000.0 0.54 0.8069 0.9981 1682976 ChemDiv1_003254 COc1ccc(cc1OC)C(=O)Nc2ccc3oc(Cc4ccc(Cl)cc4)nc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D21 compound treatment 664621.0 152000.0 0.68 683966.0 111000.0 0.55 0.8701 0.9941 1971925 ChemDiv1_003255 CCNc1nc(NCC)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D22 compound treatment 623343.0 111000.0 0.5 652551.0 79200.0 0.39 0.6294 0.9931 1971926 ChemDiv1_003256 Cc1ccc(NC(=O)c2ccc(o2)c3ccc(cc3)[N+](=O)[O-])cc1c4nc5ncccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D23 mock treatment 630133.0 118000.0 0.53 628955.0 55600.0 0.28 0.5683 0.9541 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 D24 mock treatment 481913.0 -30300.0 -0.14 503657.0 -69700.0 -0.35 -0.3398 -0.9166 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E01 compound treatment 580532.0 68400.0 0.31 578486.0 5170.0 0.03 0.2345 0.7636 1971927 ChemDiv1_003257 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(F)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E02 compound treatment 602043.0 89900.0 0.4 623738.0 50400.0 0.25 0.4611 0.9737 1530853 ChemDiv1_003258 Cc1ccc(o1)c2c(C#N)c(SCC(=O)c3ccc(O)c(O)c3)nc4CCCCc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E03 compound treatment 623891.0 112000.0 0.5 653696.0 80400.0 0.4 0.6352 0.9936 1971928 ChemDiv1_003259 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E04 compound treatment 630039.0 118000.0 0.53 656120.0 82800.0 0.41 0.6631 0.9923 1971929 ChemDiv1_003260 Cc1cccc2oc3cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c5c3[nH]c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E05 compound treatment 655389.0 143000.0 0.64 685751.0 112000.0 0.56 0.8472 0.9975 1971930 ChemDiv1_003261 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E06 compound treatment 667790.0 156000.0 0.7 674104.0 101000.0 0.5 0.8456 0.9867 1971931 ChemDiv1_003262 CC1=CC(C)(C)N(C(=O)c2sc3ccccc3c2Cl)c4ccc(cc14)C(c5ccccc5)(c6ccccc6)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E07 compound treatment 708180.0 196000.0 0.88 737904.0 165000.0 0.82 1.1969 0.9993 1971932 ChemDiv1_003263 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)ccc1OCc4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E08 compound treatment 694738.0 183000.0 0.82 703076.0 130000.0 0.64 1.0324 0.9929 1784065 ChemDiv1_003264 [O-][N+](=O)c1cc2OCOc2cc1C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc(Cl)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E09 compound treatment 711244.0 199000.0 0.89 737177.0 164000.0 0.81 1.2041 0.9989 1951589 ChemDiv1_003265 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E10 compound treatment 555210.0 43000.0 0.19 584485.0 11200.0 0.06 0.1753 0.8748 1971933 ChemDiv1_003266 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E11 compound treatment 720691.0 209000.0 0.93 724511.0 151000.0 0.75 1.1896 0.994 1946198 ChemDiv1_003267 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E12 compound treatment 707884.0 196000.0 0.88 726333.0 153000.0 0.76 1.1555 0.9974 1971934 ChemDiv1_003268 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E13 compound treatment 675756.0 164000.0 0.73 733021.0 160000.0 0.79 1.0772 0.9993 1945904 ChemDiv1_003269 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E14 compound treatment 686619.0 174000.0 0.78 727521.0 154000.0 0.76 1.0923 0.9999 1971935 ChemDiv1_003270 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E15 compound treatment 693993.0 182000.0 0.81 762678.0 189000.0 0.94 1.2388 0.9975 1945713 ChemDiv1_003271 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E16 compound treatment 663620.0 151000.0 0.68 735659.0 162000.0 0.8 1.048 0.9964 1971936 ChemDiv1_003272 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E17 compound treatment 675037.0 163000.0 0.73 741746.0 168000.0 0.83 1.1055 0.9977 1971937 ChemDiv1_003273 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC#N)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E18 compound treatment 624161.0 112000.0 0.5 710668.0 137000.0 0.68 0.8356 0.9887 1923394 ChemDiv1_003274 [O-][N+](=O)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E19 compound treatment 636801.0 125000.0 0.56 680268.0 107000.0 0.53 0.7691 0.9997 1710855 ChemDiv1_003275 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E20 compound treatment 640593.0 128000.0 0.57 693036.0 120000.0 0.59 0.8258 0.9999 1926305 ChemDiv1_003276 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E21 compound treatment 631532.0 119000.0 0.53 699604.0 126000.0 0.63 0.8202 0.9969 1971938 ChemDiv1_003277 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(C)c(c3)[N+](=O)[O-])s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E22 compound treatment 604083.0 91900.0 0.41 662067.0 88800.0 0.44 0.6018 0.9994 1971939 ChemDiv1_003278 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E23 mock treatment 587766.0 75600.0 0.34 650369.0 77100.0 0.38 0.5092 0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 E24 mock treatment 488927.0 -23200.0 -0.1 485640.0 -87700.0 -0.43 -0.3807 -0.8524 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F01 compound treatment 593222.0 81000.0 0.36 571326.0 -1990.0 -0.01 0.2496 0.6876 1971940 ChemDiv1_003279 COc1ccccc1C2CC(=NN2CN3C(=O)C(=O)c4ccccc34)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F02 compound treatment 627071.0 115000.0 0.51 602683.0 29400.0 0.15 0.4665 0.8729 1371076 ChemDiv1_003280 COC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F03 compound treatment 662849.0 151000.0 0.67 643074.0 69800.0 0.35 0.7213 0.9517 1254407 ChemDiv1_003281 CCOc1cc(OCC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4cccc(F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F04 compound treatment 672740.0 161000.0 0.72 662590.0 89300.0 0.44 0.8209 0.9728 1971941 ChemDiv1_003282 CC(C)C1=CC23CCC4C(C)(CCCC4(C)C3CC1C5C2C(=O)N(C5=O)c6ccc(cc6)S(=O)(=O)N)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F05 compound treatment 667254.0 155000.0 0.69 711590.0 138000.0 0.68 0.9752 1.0 1971942 ChemDiv1_003283 CC(C)(C)c1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F06 compound treatment 671023.0 159000.0 0.71 680249.0 107000.0 0.53 0.8774 0.9895 1391694 ChemDiv1_003284 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F07 compound treatment 724169.0 212000.0 0.95 709143.0 136000.0 0.67 1.1468 0.9858 1661399 ChemDiv1_003285 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F08 compound treatment 721748.0 210000.0 0.94 704302.0 131000.0 0.65 1.1222 0.9838 1351519 ChemDiv1_003286 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F09 compound treatment 703630.0 191000.0 0.86 715612.0 142000.0 0.7 1.1045 0.9953 1367554 ChemDiv1_003287 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C(=O)OC(C)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F10 compound treatment 705394.0 193000.0 0.86 691471.0 118000.0 0.59 1.0255 0.9819 1971943 ChemDiv1_003288 [O-][N+](=O)c1cccc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F11 compound treatment 743397.0 231000.0 1.04 729011.0 156000.0 0.77 1.2773 0.9895 1971944 ChemDiv1_003289 COc1cc(cc(OC)c1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OCCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F12 compound treatment 721234.0 209000.0 0.94 739567.0 166000.0 0.82 1.2441 0.998 1971945 ChemDiv1_003290 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F13 compound treatment 723875.0 212000.0 0.95 759610.0 186000.0 0.92 1.3227 0.9999 1971946 ChemDiv1_003291 CCNc1nc(NCC)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F14 compound treatment 693260.0 181000.0 0.81 731598.0 158000.0 0.78 1.1276 0.9999 1337077 ChemDiv1_003292 O=C(N1CCN(CC1)C(=O)c2cccc(c2)S(=O)(=O)N3CCCCC3)c4cccc(c4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F15 compound treatment 720803.0 209000.0 0.93 755641.0 182000.0 0.9 1.299 0.9999 1220453 ChemDiv1_003293 CCNc1nc(NCC)nc(NS(=O)(=O)c2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F16 compound treatment 672909.0 161000.0 0.72 712026.0 139000.0 0.69 0.9947 0.9997 1313118 ChemDiv1_003294 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F17 compound treatment 696790.0 185000.0 0.83 741528.0 168000.0 0.83 1.1736 1.0 1971947 ChemDiv1_003295 COc1nc(nc(C)c1Br)N(C)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F18 compound treatment 642372.0 130000.0 0.58 680820.0 108000.0 0.53 0.7887 0.999 1677968 ChemDiv1_003296 CN1C(=C(C(NC1=O)c2ccc(Br)s2)C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F19 compound treatment 673839.0 162000.0 0.72 726765.0 153000.0 0.76 1.0492 0.9997 1971948 ChemDiv1_003297 CCNc1nc(NCC)nc(SCCOC(=O)Nc2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F20 compound treatment 639184.0 127000.0 0.57 698692.0 125000.0 0.62 0.8412 0.999 1175787 ChemDiv1_003298 O=C(Nc1cccc(NC(=O)c2ccc3OCCOc3c2)c1)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F21 compound treatment 675127.0 163000.0 0.73 699048.0 126000.0 0.62 0.9562 0.9969 1971949 ChemDiv1_003299 CCNc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F22 compound treatment 637790.0 126000.0 0.56 675046.0 102000.0 0.5 0.754 0.9985 1971950 ChemDiv1_003300 OC(=O)C1Cc2c([nH]c3ccccc23)C(N1)c4cccc(O)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F23 mock treatment 636859.0 125000.0 0.56 659316.0 86000.0 0.43 0.6959 0.9911 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 F24 mock treatment 496392.0 -15800.0 -0.07 491817.0 -81500.0 -0.4 -0.3354 -0.8184 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G01 compound treatment 590669.0 78500.0 0.35 562093.0 -11200.0 -0.06 0.2091 0.5879 1289023 ChemDiv1_003301 COc1ccc(cc1)c2cc(C(=O)NCc3ccc4OCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G02 compound treatment 607108.0 94900.0 0.42 594919.0 21600.0 0.11 0.3762 0.8584 1971951 ChemDiv1_003302 COc1ccc(Nc2cc3sc4cc(C)ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G03 compound treatment 638969.0 127000.0 0.57 618551.0 45200.0 0.22 0.5598 0.9174 1971952 ChemDiv1_003303 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3c(OC)ccc4ccccc34)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G04 compound treatment 645186.0 133000.0 0.6 639748.0 66400.0 0.33 0.6537 0.9609 1919523 ChemDiv1_003304 OC(=O)c1cc(cc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G05 compound treatment 657954.0 146000.0 0.65 666195.0 92900.0 0.46 0.7868 0.9854 1971953 ChemDiv1_003305 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G06 compound treatment 650093.0 138000.0 0.62 648494.0 75200.0 0.37 0.6999 0.9707 1783127 ChemDiv1_003306 [O-][N+](=O)c1ccc2c(Cl)c(sc2c1)C(=O)N3c4ccccc4CCc5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G07 compound treatment 700249.0 188000.0 0.84 701737.0 128000.0 0.64 1.0451 0.9905 1945993 ChemDiv1_003307 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCc4ccc(cc4)C(=O)O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G08 compound treatment 674287.0 162000.0 0.73 689072.0 116000.0 0.57 0.9186 0.9932 1971954 ChemDiv1_003308 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G09 compound treatment 709675.0 197000.0 0.88 739132.0 166000.0 0.82 1.206 0.9993 1945817 ChemDiv1_003309 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G10 compound treatment 577873.0 65700.0 0.29 599917.0 26600.0 0.13 0.3011 0.9344 1971955 ChemDiv1_003310 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G11 compound treatment 702513.0 190000.0 0.85 739686.0 166000.0 0.82 1.1852 0.9999 1945942 ChemDiv1_003311 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G12 compound treatment 682332.0 170000.0 0.76 679870.0 107000.0 0.53 0.9118 0.984 1971956 ChemDiv1_003312 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G13 compound treatment 693186.0 181000.0 0.81 700452.0 127000.0 0.63 1.0183 0.9922 1945907 ChemDiv1_003313 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G14 compound treatment 686815.0 175000.0 0.78 723978.0 151000.0 0.75 1.0805 0.9997 1971957 ChemDiv1_003314 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G15 compound treatment 695183.0 183000.0 0.82 715783.0 142000.0 0.71 1.0783 0.9972 1946078 ChemDiv1_003315 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G16 compound treatment 647998.0 136000.0 0.61 716675.0 143000.0 0.71 0.9321 0.997 1971958 ChemDiv1_003316 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G17 compound treatment 671373.0 159000.0 0.71 750750.0 177000.0 0.88 1.1254 0.9946 1971959 ChemDiv1_003317 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC=C)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G18 compound treatment 634785.0 123000.0 0.55 674033.0 101000.0 0.5 0.7409 0.9989 1971960 ChemDiv1_003318 CN1C(=O)N(C)C(=O)C(=Cc2cc(Br)ccc2OCCOc3ccccc3)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G19 compound treatment 647285.0 135000.0 0.6 678612.0 105000.0 0.52 0.7965 0.9973 1171559 ChemDiv1_003319 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)CSc3ccc(Cl)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G20 compound treatment 623996.0 112000.0 0.5 682679.0 109000.0 0.54 0.737 0.9992 1946489 ChemDiv1_003320 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G21 compound treatment 630529.0 118000.0 0.53 666899.0 93600.0 0.46 0.7024 0.9978 1971961 ChemDiv1_003321 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccco3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G22 compound treatment 612127.0 100000.0 0.45 662590.0 89300.0 0.44 0.6291 1.0 1946403 ChemDiv1_003322 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G23 mock treatment 622836.0 111000.0 0.5 650198.0 76900.0 0.38 0.6196 0.9916 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 G24 mock treatment 498349.0 -13800.0 -0.06 486195.0 -87100.0 -0.43 -0.3489 -0.8003 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H01 compound treatment 594289.0 82100.0 0.37 569872.0 -3440.0 -0.02 0.2479 0.6736 1971962 ChemDiv1_003323 COc1ccc(cc1)C2=NN(CN3C(=O)C(=O)c4ccccc34)C(C2)c5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H02 compound treatment 619159.0 107000.0 0.48 612757.0 39400.0 0.2 0.4768 0.9218 1579638 ChemDiv1_003324 CC1(C)NC(=O)N(CC(O)COc2ccc(cc2)N3C(=O)C4CC=CCC4C3=O)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H03 compound treatment 668179.0 156000.0 0.7 614008.0 40700.0 0.2 0.6363 0.8755 1410958 ChemDiv1_003325 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3C)c4nc5ccc(C)cc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H04 compound treatment 636230.0 124000.0 0.56 638043.0 64700.0 0.32 0.6194 0.9659 1971963 ChemDiv1_003326 CCCCOC(=O)c1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H05 compound treatment 628115.0 116000.0 0.52 648407.0 75100.0 0.37 0.63 0.9867 1784066 ChemDiv1_003327 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H06 compound treatment 680964.0 169000.0 0.76 654894.0 81600.0 0.4 0.82 0.957 1408916 ChemDiv1_003328 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H07 compound treatment 705838.0 194000.0 0.87 696518.0 123000.0 0.61 1.0446 0.9852 1396747 ChemDiv1_003329 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(Cl)c(O)c(OC)c4)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H08 compound treatment 703112.0 191000.0 0.85 673125.0 99800.0 0.49 0.954 0.9661 1971964 ChemDiv1_003330 [O-][N+](=O)c1ccccc1C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H09 compound treatment 711014.0 199000.0 0.89 689268.0 116000.0 0.57 1.0355 0.9775 1682517 ChemDiv1_003331 CCOc1cc(cc(Cl)c1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCc4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H10 compound treatment 690373.0 178000.0 0.8 707111.0 134000.0 0.66 1.0327 0.9958 1971965 ChemDiv1_003332 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H11 compound treatment 707676.0 196000.0 0.88 695594.0 122000.0 0.61 1.0471 0.9839 1971966 ChemDiv1_003333 COCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H12 compound treatment 683773.0 172000.0 0.77 684325.0 111000.0 0.55 0.932 0.9866 1590612 ChemDiv1_003334 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cccc(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H13 compound treatment 717774.0 206000.0 0.92 708867.0 136000.0 0.67 1.1256 0.988 1971967 ChemDiv1_003335 CCNc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H14 compound treatment 679405.0 167000.0 0.75 719610.0 146000.0 0.72 1.0418 0.9999 1215375 ChemDiv1_003336 CC1CCN(CC1)S(=O)(=O)c2cc(ccc2C)C(=O)Oc3cccc4cccnc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H15 compound treatment 725617.0 213000.0 0.96 732922.0 160000.0 0.79 1.2347 0.9956 1588087 ChemDiv1_003337 CCNc1nc(NC(C)C)nc(NS(=O)(=O)c2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H16 compound treatment 666660.0 154000.0 0.69 726038.0 153000.0 0.76 1.024 0.999 1248308 ChemDiv1_003338 COc1ccc(cc1OC)C2NCCc3c2[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H17 compound treatment 688197.0 176000.0 0.79 743116.0 170000.0 0.84 1.1519 0.9995 1971968 ChemDiv1_003339 CN(C)c1nc(OCCOC(=O)Nc2ccccc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H18 compound treatment 658479.0 146000.0 0.65 691719.0 118000.0 0.59 0.8778 0.9985 1971969 ChemDiv1_003340 CN1C(=C(C(NC1=O)c2ccc(cc2)C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H19 compound treatment 655647.0 143000.0 0.64 730502.0 157000.0 0.78 1.0047 0.9954 1971970 ChemDiv1_003341 CN(C)c1nc(SCCOC(=O)c2ccccc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H20 compound treatment 625367.0 113000.0 0.51 672505.0 99200.0 0.49 0.7057 0.9999 1601010 ChemDiv1_003342 O=C(Nc1ccc2nn(nc2c1)c3cccc4ccccc34)c5ccc6OCCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H21 compound treatment 656579.0 144000.0 0.65 652851.0 79500.0 0.39 0.7357 0.9718 1971971 ChemDiv1_003343 CC(C)Nc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H22 compound treatment 602261.0 90100.0 0.4 670035.0 96700.0 0.48 0.6239 0.9963 1136747 ChemDiv1_003344 Cn1c(=O)n(C)c2n(Cc3ccc(Cl)cc3Cl)c(SCC(=O)O)nc2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H23 mock treatment 614732.0 103000.0 0.46 647072.0 73800.0 0.37 0.583 0.9936 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 H24 mock treatment 517173.0 5000.0 0.02 506787.0 -66500.0 -0.33 -0.2172 -0.6576 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I01 compound treatment 577928.0 65800.0 0.29 564712.0 -8600.0 -0.04 0.178 0.5985 1624173 ChemDiv1_003345 COc1cccc(c1)c2cc(C(=O)Nc3ccncc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I02 compound treatment 594347.0 82200.0 0.37 588773.0 15500.0 0.08 0.3142 0.8364 1971972 ChemDiv1_003346 CC(C)(C)c1ccc2[nH]c3c(cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I03 compound treatment 702191.0 190000.0 0.85 698101.0 125000.0 0.62 1.0386 0.9877 1971973 ChemDiv1_003347 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Br)c(O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I04 compound treatment 629559.0 117000.0 0.53 576677.0 3360.0 0.02 0.3833 0.7291 1971974 ChemDiv1_003348 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccc(Oc5ccc6C(=O)N(C(=O)c6c5)c7ccccc7)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I05 compound treatment 617154.0 105000.0 0.47 669537.0 96200.0 0.48 0.6693 1.0 1971975 ChemDiv1_003349 Cc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I06 compound treatment 603297.0 91100.0 0.41 602441.0 29100.0 0.14 0.3904 0.9024 1971976 ChemDiv1_003350 CC1CC(N(C(=O)c2sc3cc(ccc3c2Cl)[N+](=O)[O-])c4ccccc4)c5ccccc5N1C(=O)Cc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I07 compound treatment 691531.0 179000.0 0.8 662603.0 89300.0 0.44 0.8805 0.9605 1971977 ChemDiv1_003351 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1OCc4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I08 compound treatment 668521.0 156000.0 0.7 660716.0 87400.0 0.43 0.801 0.9734 1587570 ChemDiv1_003352 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I09 compound treatment 704251.0 192000.0 0.86 682665.0 109000.0 0.54 0.991 0.9752 1928313 ChemDiv1_003353 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I10 compound treatment 760717.0 249000.0 1.11 821206.0 248000.0 1.23 1.655 0.9988 1126339 ChemDiv1_003354 OC(=O)c1cccc2C3C=CCC3C(Nc12)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I11 compound treatment 696347.0 184000.0 0.82 717758.0 144000.0 0.72 1.0889 0.9975 1951821 ChemDiv1_003355 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I12 compound treatment 682361.0 170000.0 0.76 681681.0 108000.0 0.54 0.9183 0.9853 1971978 ChemDiv1_003356 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I13 compound treatment 666660.0 154000.0 0.69 703460.0 130000.0 0.64 0.9449 0.9994 1946266 ChemDiv1_003357 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I14 compound treatment 671621.0 159000.0 0.71 667647.0 94300.0 0.47 0.8351 0.9789 1971979 ChemDiv1_003358 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCCOc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I15 compound treatment 707390.0 195000.0 0.87 735906.0 163000.0 0.81 1.1874 0.9992 1971980 ChemDiv1_003359 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I16 compound treatment 631317.0 119000.0 0.53 680786.0 107000.0 0.53 0.7536 1.0 1927744 ChemDiv1_003360 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Cl)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I17 compound treatment 681180.0 169000.0 0.76 717978.0 145000.0 0.72 1.0417 0.9996 1946082 ChemDiv1_003361 Nc1ccc2nc(SCC(=O)NCCOc3ccc(Cl)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I18 compound treatment 622792.0 111000.0 0.5 684136.0 111000.0 0.55 0.7383 0.9987 1971981 ChemDiv1_003362 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OCCOc3ccc(cc3)[N+](=O)[O-])C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I19 compound treatment 608272.0 96100.0 0.43 715676.0 142000.0 0.71 0.8028 0.9719 1971982 ChemDiv1_003363 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)CN3CCOCC3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I20 compound treatment 618254.0 106000.0 0.47 684656.0 111000.0 0.55 0.7258 0.9972 1971983 ChemDiv1_003364 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCBr 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I21 compound treatment 621820.0 110000.0 0.49 692359.0 119000.0 0.59 0.764 0.9958 1531569 ChemDiv1_003365 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I22 compound treatment 603051.0 90900.0 0.41 619012.0 45700.0 0.23 0.4477 0.9617 1452631 ChemDiv1_003366 Cc1ccc(cc1)n2c(=O)c3c4CCCc4sc3[nH]c2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I23 mock treatment 613372.0 101000.0 0.45 647810.0 74500.0 0.37 0.5813 0.9948 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 I24 mock treatment 489964.0 -22200.0 -0.1 492183.0 -81100.0 -0.4 -0.3545 -0.8562 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J01 compound treatment 611944.0 99800.0 0.45 585945.0 12600.0 0.06 0.36 0.7984 1661937 ChemDiv1_003367 COc1ccc(cc1)C2CC(=NN2C(=O)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J02 compound treatment 631441.0 119000.0 0.53 600006.0 26700.0 0.13 0.471 0.8564 1026994 ChemDiv1_003368 O=C1N(Cc2ccccc2)S(=O)(=O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J03 compound treatment 616812.0 105000.0 0.47 655202.0 81900.0 0.41 0.618 0.9974 1532122 ChemDiv1_003369 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3ccc(O)c(c3)c4nc5cc(C)ccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J04 compound treatment 636385.0 124000.0 0.56 643057.0 69700.0 0.35 0.6375 0.9738 1692805 ChemDiv1_003370 NC(=O)c1c(NC(=O)c2cc3cc(Br)ccc3oc2=O)sc4CCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J05 compound treatment 667564.0 155000.0 0.7 677126.0 104000.0 0.51 0.8555 0.989 1971984 ChemDiv1_003371 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(C)C)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J06 compound treatment 680786.0 169000.0 0.75 656164.0 82800.0 0.41 0.8239 0.959 1658192 ChemDiv1_003372 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccccc5c4=O)C(=O)CCC3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J07 compound treatment 693888.0 182000.0 0.81 685122.0 112000.0 0.55 0.9668 0.9825 1971985 ChemDiv1_003373 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J08 compound treatment 677650.0 165000.0 0.74 698850.0 126000.0 0.62 0.9635 0.9962 1971986 ChemDiv1_003374 [O-][N+](=O)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J09 compound treatment 671341.0 159000.0 0.71 707536.0 134000.0 0.66 0.974 0.9994 1575886 ChemDiv1_003375 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J10 compound treatment 683443.0 171000.0 0.77 697531.0 124000.0 0.62 0.9772 0.9941 1265001 ChemDiv1_003376 O=C(N1CCN(Cc2ccccc2)CC1)c3cc(nc4ccccc34)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J11 compound treatment 703312.0 191000.0 0.86 701986.0 129000.0 0.64 1.0557 0.9895 1580220 ChemDiv1_003377 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J12 compound treatment 695785.0 184000.0 0.82 709383.0 136000.0 0.67 1.0578 0.9952 1630930 ChemDiv1_003378 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2c4coc5c(Cl)cc(Cl)cc5c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J13 compound treatment 698005.0 186000.0 0.83 713269.0 140000.0 0.69 1.0784 0.9959 1971987 ChemDiv1_003379 CC(C)Nc1nc(NC(C)C)nc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J14 compound treatment 698025.0 186000.0 0.83 685531.0 112000.0 0.56 0.9813 0.9808 1396540 ChemDiv1_003380 CCOC(=O)c1sc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCCC3)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J15 compound treatment 660444.0 148000.0 0.66 726267.0 153000.0 0.76 1.0051 0.9978 1459151 ChemDiv1_003381 COc1nc(NS(=O)(=O)c2ccc(NC(=O)C)cc2)nc(C)c1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J16 compound treatment 673693.0 162000.0 0.72 722423.0 149000.0 0.74 1.0336 0.9999 1506608 ChemDiv1_003382 COc1ccc(cc1)C2NCCc3c2[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J17 compound treatment 681320.0 169000.0 0.76 734025.0 161000.0 0.8 1.0983 0.9997 1971988 ChemDiv1_003383 CCNc1nc(NCC)nc(OCCOC(=O)Nc2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J18 compound treatment 642367.0 130000.0 0.58 712294.0 139000.0 0.69 0.8989 0.9966 1521396 ChemDiv1_003384 CCOc1cc(cc(Cl)c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J19 compound treatment 653139.0 141000.0 0.63 696232.0 123000.0 0.61 0.8767 0.9998 1971989 ChemDiv1_003385 CCNc1nc(NCC)nc(SCCOC(=O)c2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J20 compound treatment 611173.0 99000.0 0.44 668378.0 95100.0 0.47 0.6463 0.9995 1714049 ChemDiv1_003386 CCOc1cc(ccc1OCc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J21 compound treatment 645276.0 133000.0 0.6 701782.0 128000.0 0.64 0.8713 0.9995 1327959 ChemDiv1_003387 COc1nc(nc(C)c1Cl)N(CC=C)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J22 compound treatment 619946.0 108000.0 0.48 668202.0 94900.0 0.47 0.6735 0.9999 1971990 ChemDiv1_003388 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(Cl)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J23 mock treatment 625003.0 113000.0 0.51 666044.0 92700.0 0.46 0.6819 0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 J24 mock treatment 271133.0 -241000.0 -1.08 482311.0 -91000.0 -0.45 -1.0817 -0.925 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K01 compound treatment 585181.0 73000.0 0.33 566632.0 -6680.0 -0.03 0.2077 0.6322 1939971 ChemDiv1_003389 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)c3sc4cc(C)ccc4c3Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K02 compound treatment 572486.0 60300.0 0.27 569045.0 -4270.0 -0.02 0.1759 0.6497 1971991 ChemDiv1_003390 Cc1ccc(Nc2cc3oc4cc(ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)C(C)(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K03 compound treatment 609124.0 96900.0 0.43 631904.0 58600.0 0.29 0.5121 0.9809 1946111 ChemDiv1_003391 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(o3)c4ccc(cc4)C(=O)O)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K04 compound treatment 607919.0 95700.0 0.43 571252.0 -2060.0 -0.01 0.2958 0.69 1538577 ChemDiv1_003392 CCOC(=O)CCN1C(=O)c2ccccc2S1(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K05 compound treatment 630962.0 119000.0 0.53 609520.0 36200.0 0.18 0.5028 0.896 1971992 ChemDiv1_003393 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K06 compound treatment 635262.0 123000.0 0.55 604313.0 31000.0 0.15 0.4982 0.871 1971993 ChemDiv1_003394 Cc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])c5ccccc52 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K07 compound treatment 671728.0 160000.0 0.71 678669.0 105000.0 0.52 0.8741 0.9881 1971994 ChemDiv1_003395 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)ccc1OCc4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K08 compound treatment 654486.0 142000.0 0.64 647602.0 74300.0 0.37 0.7107 0.966 1971995 ChemDiv1_003396 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc4ccccc34)C(=O)CC(C2)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K09 compound treatment 682453.0 170000.0 0.76 685770.0 112000.0 0.56 0.9329 0.9881 1971996 ChemDiv1_003397 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K10 compound treatment 2091227.0 1580000.0 7.07 2300559.0 1730000.0 8.56 11.0484 0.9955 1124004 ChemDiv1_003398 OC(=O)c1cc2C3C=CCC3CN4C(C5CC=CC5c(c1)c42)c6ccccc6F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K11 compound treatment 696811.0 185000.0 0.83 703435.0 130000.0 0.64 1.0402 0.9924 1971997 ChemDiv1_003399 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K12 compound treatment 638343.0 126000.0 0.56 669700.0 96400.0 0.48 0.737 0.9965 1971998 ChemDiv1_003400 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K13 compound treatment 666587.0 154000.0 0.69 665152.0 91800.0 0.45 0.8104 0.9794 1946027 ChemDiv1_003401 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K14 compound treatment 632915.0 121000.0 0.54 673919.0 101000.0 0.5 0.7346 0.9992 1927017 ChemDiv1_003402 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K15 compound treatment 667079.0 155000.0 0.69 702840.0 130000.0 0.64 0.944 0.9992 1946141 ChemDiv1_003403 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K16 compound treatment 662426.0 150000.0 0.67 696609.0 123000.0 0.61 0.9075 0.9988 1971999 ChemDiv1_003404 COc1ccccc1OCCOc2c(Cl)cc(C=C3C(=O)N(C)C(=O)N(C)C3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K17 compound treatment 639705.0 128000.0 0.57 702160.0 129000.0 0.64 0.855 0.9985 1933204 ChemDiv1_003405 CCOc1ccc2nc(SCc3c[nH]c4cc(ccc34)[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K18 compound treatment 621956.0 110000.0 0.49 673684.0 100000.0 0.5 0.6991 1.0 1972000 ChemDiv1_003406 [O-][N+](=O)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K19 compound treatment 623738.0 112000.0 0.5 695624.0 122000.0 0.61 0.7816 0.9954 1972001 ChemDiv1_003407 Brc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3cccs3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K20 compound treatment 590271.0 78100.0 0.35 673759.0 100000.0 0.5 0.599 0.9851 1972002 ChemDiv1_003408 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCBr 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K21 compound treatment 606059.0 93900.0 0.42 649066.0 75800.0 0.38 0.5625 0.9984 1972003 ChemDiv1_003409 Cc1ccc(cc1C)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)[N+](=O)[O-])s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K22 compound treatment 589111.0 76900.0 0.34 644169.0 70900.0 0.35 0.4917 1.0 1933479 ChemDiv1_003410 CCn1c(SCC(=O)c2ccccc2)nc3sc4COC(C)(C)Cc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K23 mock treatment 605113.0 92900.0 0.42 640831.0 67500.0 0.33 0.5307 0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 K24 mock treatment 482238.0 -29900.0 -0.13 517542.0 -55800.0 -0.28 -0.2901 -0.9448 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L01 compound treatment 598621.0 86400.0 0.39 598766.0 25500.0 0.13 0.3628 0.8914 1610231 ChemDiv1_003411 OC(=O)CCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L02 compound treatment 610485.0 98300.0 0.44 609705.0 36400.0 0.18 0.4386 0.9224 1182586 ChemDiv1_003412 NC(=O)CN1C(=O)c2ccccc2S1(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L03 compound treatment 623951.0 112000.0 0.5 635538.0 62200.0 0.31 0.5718 0.9729 1339606 ChemDiv1_003413 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccc(OC)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L04 compound treatment 634110.0 122000.0 0.55 632240.0 58900.0 0.29 0.5924 0.957 1949633 ChemDiv1_003414 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc3cc(Br)ccc3oc2=O)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L05 compound treatment 653962.0 142000.0 0.63 668331.0 95000.0 0.47 0.7816 0.9892 1356931 ChemDiv1_003415 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L06 compound treatment 627066.0 115000.0 0.51 644044.0 70700.0 0.35 0.6114 0.9825 1222926 ChemDiv1_003416 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccccc4c3=O)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L07 compound treatment 678574.0 166000.0 0.74 670845.0 97500.0 0.48 0.8683 0.978 1140644 ChemDiv1_003417 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L08 compound treatment 673247.0 161000.0 0.72 664081.0 90800.0 0.45 0.8278 0.9742 1700704 ChemDiv1_003418 Cc1nc2ccccc2c(=O)n1NC(=O)c3cc(nc4ccccc34)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L09 compound treatment 674523.0 162000.0 0.73 689401.0 116000.0 0.58 0.9205 0.9933 1374217 ChemDiv1_003419 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)c(OC)c4)C(=O)OCC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L10 compound treatment 673558.0 161000.0 0.72 688540.0 115000.0 0.57 0.9144 0.9932 1972004 ChemDiv1_003420 CC(=O)c1sc(nc1C)N2N=C(CC2c3ccc(F)cc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L11 compound treatment 715348.0 203000.0 0.91 729336.0 156000.0 0.77 1.1896 0.9967 1349609 ChemDiv1_003421 CCCOc1ccc(cc1)C2NC(=O)NC(=C2C(=O)OCc3ccc(OC)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L12 compound treatment 671135.0 159000.0 0.71 713613.0 140000.0 0.7 0.9946 0.9999 1972005 ChemDiv1_003422 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L13 compound treatment 639875.0 128000.0 0.57 690403.0 117000.0 0.58 0.8143 1.0 1621369 ChemDiv1_003423 Cc1cc(C)nc(n1)N(CN2C(=O)c3ccccc3S2(=O)=O)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L14 compound treatment 678226.0 166000.0 0.74 709023.0 136000.0 0.67 1.001 0.9987 1422482 ChemDiv1_003424 Nc1nc(CSc2nc(N)c3nc[nH]c3n2)cs1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L15 compound treatment 651203.0 139000.0 0.62 702405.0 129000.0 0.64 0.8922 0.9999 1481333 ChemDiv1_003425 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccc(C)cc3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L16 compound treatment 656929.0 145000.0 0.65 683168.0 110000.0 0.54 0.843 0.9962 1558798 ChemDiv1_003426 CCOc1cc(cc(Cl)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L17 compound treatment 639612.0 127000.0 0.57 713295.0 140000.0 0.69 0.8937 0.9953 1972006 ChemDiv1_003427 CN(C)c1nc(OCCOC(=O)c2ccccc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L18 compound treatment 631643.0 119000.0 0.53 678498.0 105000.0 0.52 0.7466 0.9999 1406508 ChemDiv1_003428 COc1cc(cc(OC)c1OC)C(=O)N2N=C(CC2c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L19 compound treatment 619051.0 107000.0 0.48 667531.0 94200.0 0.47 0.6683 0.9999 1972007 ChemDiv1_003429 CCNc1nc(NC(C)C)nc(SCCOc2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L20 compound treatment 599358.0 87200.0 0.39 689623.0 116000.0 0.58 0.6834 0.982 1972008 ChemDiv1_003430 CCOC(=O)c1ccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L21 compound treatment 631309.0 119000.0 0.53 681060.0 108000.0 0.53 0.7545 1.0 1300331 ChemDiv1_003431 COc1nc(nc(C)c1Br)N(CC=C)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L22 compound treatment 603403.0 91200.0 0.41 675486.0 102000.0 0.51 0.6467 0.9943 1972009 ChemDiv1_003432 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L23 mock treatment 577918.0 65700.0 0.29 652869.0 79600.0 0.39 0.4868 0.9897 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 L24 mock treatment 204373.0 -308000.0 -1.38 507122.0 -66200.0 -0.33 -1.2061 -0.8516 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M01 compound treatment 586493.0 74300.0 0.33 557933.0 -15400.0 -0.08 0.1814 0.5314 1705941 ChemDiv1_003433 Cc1ccc(o1)c2cc(C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M02 compound treatment 605976.0 93800.0 0.42 580490.0 7170.0 0.04 0.322 0.7642 1972010 ChemDiv1_003434 CC(C)(C)c1ccc2[nH]c3c(cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M03 compound treatment 619572.0 107000.0 0.48 612073.0 38800.0 0.19 0.4757 0.9189 1972011 ChemDiv1_003435 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M04 compound treatment 619811.0 108000.0 0.48 611851.0 38500.0 0.19 0.4757 0.9178 1530636 ChemDiv1_003436 CC1CC(Nc2ccc(C)cc2)c3cccc(C)c3N1C(=O)c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M05 compound treatment 620030.0 108000.0 0.48 600847.0 27500.0 0.14 0.4378 0.8727 1972012 ChemDiv1_003437 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(Cl)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M06 compound treatment 635274.0 123000.0 0.55 601079.0 27800.0 0.14 0.4869 0.8573 1523741 ChemDiv1_003438 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M07 compound treatment 672201.0 160000.0 0.72 665171.0 91900.0 0.46 0.8283 0.976 1972013 ChemDiv1_003439 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccc(cc4)C(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M08 compound treatment 643937.0 132000.0 0.59 625976.0 52700.0 0.26 0.6015 0.9327 1161372 ChemDiv1_003440 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccncc4)C(=O)OCCc5ccccc5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M09 compound treatment 663715.0 152000.0 0.68 662190.0 88900.0 0.44 0.791 0.9781 1945768 ChemDiv1_003441 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M10 compound treatment 635982.0 124000.0 0.55 662963.0 89600.0 0.44 0.7059 0.994 1736489 ChemDiv1_003442 CCOC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M11 compound treatment 671354.0 159000.0 0.71 659370.0 86100.0 0.43 0.8053 0.9698 1972014 ChemDiv1_003443 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M12 compound treatment 618627.0 106000.0 0.48 650150.0 76800.0 0.38 0.6061 0.9938 1972015 ChemDiv1_003444 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCCOc3cccc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M13 compound treatment 639650.0 127000.0 0.57 663706.0 90400.0 0.45 0.7201 0.9928 1972016 ChemDiv1_003445 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)OC)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M14 compound treatment 623714.0 112000.0 0.5 667827.0 94500.0 0.47 0.6841 0.9995 1943089 ChemDiv1_003446 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M15 compound treatment 629385.0 117000.0 0.52 684840.0 112000.0 0.55 0.7617 0.9997 1946074 ChemDiv1_003447 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M16 compound treatment 637335.0 125000.0 0.56 681815.0 108000.0 0.54 0.7762 0.9998 1972017 ChemDiv1_003448 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Br)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M17 compound treatment 639960.0 128000.0 0.57 689485.0 116000.0 0.58 0.8114 1.0 1413611 ChemDiv1_003449 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc4ccccc4c3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M18 compound treatment 597839.0 85700.0 0.38 663520.0 90200.0 0.45 0.5871 0.9971 1923260 ChemDiv1_003450 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M19 compound treatment 611545.0 99400.0 0.44 677692.0 104000.0 0.52 0.6801 0.9972 1783241 ChemDiv1_003451 Cc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(C)c(c3)[N+](=O)[O-])s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M20 compound treatment 582499.0 70300.0 0.31 641078.0 67800.0 0.34 0.46 0.9995 1943259 ChemDiv1_003452 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M21 compound treatment 598945.0 86800.0 0.39 673853.0 101000.0 0.5 0.6268 0.9924 1356589 ChemDiv1_003453 COc1cccc(c1)C(=O)Nc2nnc(CCS(=O)(=O)c3cc(Cl)ccc3Cl)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M22 compound treatment 578902.0 66700.0 0.3 640156.0 66800.0 0.33 0.4453 0.9987 1972018 ChemDiv1_003454 CC1(C)Cc2c(CO1)sc3nc(SCC#N)n(c4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M23 mock treatment 597018.0 84800.0 0.38 645708.0 72400.0 0.36 0.5221 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 M24 mock treatment 468921.0 -43300.0 -0.19 540665.0 -32700.0 -0.16 -0.2513 -0.996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N01 compound treatment 585223.0 73000.0 0.33 584500.0 11200.0 0.06 0.2704 0.8153 1972019 ChemDiv1_003455 COc1ccc(cc1OC)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N02 compound treatment 611181.0 99000.0 0.44 595481.0 22200.0 0.11 0.391 0.8564 1710765 ChemDiv1_003456 OC(COc1ccc2ccccc2c1)CN3C(=O)c4ccccc4S3(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N03 compound treatment 642959.0 131000.0 0.59 619755.0 46400.0 0.23 0.5766 0.9167 1972020 ChemDiv1_003457 COc1cc(cc(OC)c1OC)C(=O)OCCCNC2=NS(=O)(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N04 compound treatment 614623.0 102000.0 0.46 614756.0 41400.0 0.21 0.4694 0.9343 1972021 ChemDiv1_003458 CCOCCOC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N05 compound treatment 633335.0 121000.0 0.54 649446.0 76100.0 0.38 0.6502 0.9842 1784068 ChemDiv1_003459 CCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3[N+](=O)[O-])C(=O)CC(C2)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N06 compound treatment 630917.0 119000.0 0.53 608402.0 35100.0 0.17 0.4988 0.8919 1415476 ChemDiv1_003460 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N07 compound treatment 633934.0 122000.0 0.55 695158.0 122000.0 0.6 0.8122 0.9987 1972022 ChemDiv1_003461 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3[N+](=O)[O-])C(=O)CC(C2)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N08 compound treatment 638694.0 127000.0 0.57 631065.0 57700.0 0.29 0.6028 0.95 1430680 ChemDiv1_003462 COc1ccc(cc1Br)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N09 compound treatment 652361.0 140000.0 0.63 683734.0 110000.0 0.55 0.8305 0.9977 1972023 ChemDiv1_003463 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(O)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N10 compound treatment 623766.0 112000.0 0.5 657478.0 84200.0 0.42 0.648 0.996 1972024 ChemDiv1_003464 CCCCc1c(C#N)c(N)nc2sc(C(=O)c3ccc(cc3)[N+](=O)[O-])c(N)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N11 compound treatment 670808.0 159000.0 0.71 685921.0 113000.0 0.56 0.8966 0.9929 1242152 ChemDiv1_003465 CC1=C(C(NC(=O)N1)c2ccc(OCc3ccccc3)cc2)C(=O)OCC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N12 compound treatment 628623.0 116000.0 0.52 674933.0 102000.0 0.5 0.7245 0.9998 1242806 ChemDiv1_003466 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N13 compound treatment 627735.0 116000.0 0.52 678183.0 105000.0 0.52 0.7331 1.0 1972025 ChemDiv1_003467 Cc1cc(C)n(n1)c2cc(C)nc(N)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N14 compound treatment 627588.0 115000.0 0.52 677026.0 104000.0 0.51 0.7286 1.0 1925786 ChemDiv1_003468 Cc1nnc(SCC(=O)OCN2C(=O)c3ccccc3C2=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N15 compound treatment 637053.0 125000.0 0.56 652609.0 79300.0 0.39 0.673 0.9851 1354691 ChemDiv1_003469 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccccc3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N16 compound treatment 603871.0 91700.0 0.41 660196.0 86900.0 0.43 0.5946 0.9997 1947478 ChemDiv1_003470 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N17 compound treatment 649205.0 137000.0 0.61 694343.0 121000.0 0.6 0.8577 0.9999 1972026 ChemDiv1_003471 CCNc1nc(NCC)nc(OCCOC(=O)c2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N18 compound treatment 617119.0 105000.0 0.47 672449.0 99100.0 0.49 0.6794 0.9998 1972027 ChemDiv1_003472 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N19 compound treatment 609128.0 97000.0 0.43 670058.0 96700.0 0.48 0.6458 0.9988 1972028 ChemDiv1_003473 CCOc1nc(SCCOc2ccccc2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N20 compound treatment 604859.0 92700.0 0.41 673270.0 100000.0 0.5 0.6435 0.9961 1951367 ChemDiv1_003474 CCOc1c(Br)cc(cc1OC)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N21 compound treatment 610500.0 98300.0 0.44 664850.0 91500.0 0.45 0.6319 0.9999 1590736 ChemDiv1_003475 COc1cc(C)nc(n1)N(Cc2ccccc2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N22 compound treatment 579887.0 67700.0 0.3 636914.0 63600.0 0.32 0.4371 0.9998 1972029 ChemDiv1_003476 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N23 mock treatment 585181.0 73000.0 0.33 663018.0 89700.0 0.44 0.5453 0.9886 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 N24 mock treatment 261983.0 -250000.0 -1.12 515918.0 -57400.0 -0.28 -0.993 -0.8594 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O01 compound treatment 575425.0 63200.0 0.28 559155.0 -14200.0 -0.07 0.1506 0.5163 1706680 ChemDiv1_003477 Cc1cc(NC(=O)c2cc(nc3ccccc23)c4ccc(Br)cc4)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O02 compound treatment 572248.0 60100.0 0.27 557716.0 -15600.0 -0.08 0.1355 0.4843 1972030 ChemDiv1_003478 Cc1ccc(Nc2cc3oc4cc(C)ccc4[nH]c3c5c(=O)c6ccccc6c(=O)c25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O03 compound treatment 616000.0 104000.0 0.46 606623.0 33300.0 0.16 0.4453 0.9029 1972031 ChemDiv1_003479 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OC(=O)c4cccs4)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O04 compound treatment 569267.0 57100.0 0.26 553861.0 -19500.0 -0.1 0.1126 0.4121 1202017 ChemDiv1_003480 COc1ccc2c(C)nc(Nc3nc(O)cc(n3)c4ccccc4)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O05 compound treatment 588737.0 76600.0 0.34 622246.0 48900.0 0.24 0.4137 0.9856 1972032 ChemDiv1_003481 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccccc4C#N)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O06 compound treatment 608993.0 96800.0 0.43 558863.0 -14500.0 -0.07 0.2558 0.5824 1972033 ChemDiv1_003482 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O07 compound treatment 620868.0 109000.0 0.49 631714.0 58400.0 0.29 0.5486 0.9692 1928207 ChemDiv1_003483 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OCC(=O)O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O08 compound treatment 583087.0 70900.0 0.32 598781.0 25500.0 0.13 0.3137 0.9183 1972034 ChemDiv1_003484 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O09 compound treatment 604105.0 91900.0 0.41 604726.0 31400.0 0.16 0.401 0.9115 1972035 ChemDiv1_003485 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(cc3)C(C)C)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O10 compound treatment 587110.0 74900.0 0.34 608483.0 35200.0 0.17 0.3604 0.9534 1673480 ChemDiv1_003486 CN(C)CCn1c(NC(=O)c2ccc(Cl)cc2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O11 compound treatment 601758.0 89600.0 0.4 643057.0 69700.0 0.35 0.5278 0.9972 1945589 ChemDiv1_003487 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O12 compound treatment 586119.0 73900.0 0.33 602784.0 29500.0 0.15 0.3373 0.9323 1972036 ChemDiv1_003488 COc1ccccc1OCCOc2c(Cl)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O13 compound treatment 599306.0 87100.0 0.39 635291.0 62000.0 0.31 0.4929 0.993 1972037 ChemDiv1_003489 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O14 compound treatment 595775.0 83600.0 0.37 583721.0 10400.0 0.05 0.3011 0.797 1972038 ChemDiv1_003490 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O15 compound treatment 615105.0 103000.0 0.46 621972.0 48700.0 0.24 0.4962 0.9543 1972039 ChemDiv1_003491 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)OC)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O16 compound treatment 585795.0 73600.0 0.33 618524.0 45200.0 0.22 0.3914 0.9823 1972040 ChemDiv1_003492 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)N(C)C(=O)N(C)C3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O17 compound treatment 577085.0 64900.0 0.29 658008.0 84700.0 0.42 0.5021 0.9839 1487104 ChemDiv1_003493 COc1ccc(cc1OC)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(C)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O18 compound treatment 569959.0 57800.0 0.26 615984.0 42700.0 0.21 0.3324 0.995 1972041 ChemDiv1_003494 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O19 compound treatment 583835.0 71700.0 0.32 639112.0 65800.0 0.33 0.4573 1.0 1783242 ChemDiv1_003495 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Cl)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O20 compound treatment 544515.0 32300.0 0.14 610396.0 37100.0 0.18 0.2323 0.9931 1926411 ChemDiv1_003496 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCCOc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O21 compound treatment 593879.0 81700.0 0.37 638846.0 65500.0 0.32 0.4882 0.9982 1972042 ChemDiv1_003497 O=C/1N\C(=N\S(=O)(=O)c2ccccc2)\S\C1=C/c3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O22 compound treatment 548880.0 36700.0 0.16 596903.0 23600.0 0.12 0.1988 0.9861 1932970 ChemDiv1_003498 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O23 mock treatment 586750.0 74600.0 0.33 605071.0 31800.0 0.16 0.3473 0.9411 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 O24 mock treatment 276786.0 -235000.0 -1.05 172328.0 -401000.0 -1.99 -2.1497 -0.956 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P01 compound treatment 566027.0 53900.0 0.24 555926.0 -17400.0 -0.09 0.1095 0.4279 1540792 ChemDiv1_003499 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P02 compound treatment 564107.0 51900.0 0.23 568575.0 -4740.0 -0.02 0.1478 0.6325 1443933 ChemDiv1_003500 COC(=O)c1ccc(OCC(O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P03 compound treatment 583199.0 71000.0 0.32 579866.0 6550.0 0.03 0.2478 0.7753 1972043 ChemDiv1_003501 COc1ccc(cc1)C(=O)OCCCN(C2=NS(=O)(=O)c3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P04 compound treatment 571086.0 58900.0 0.26 579069.0 5750.0 0.03 0.2066 0.779 1605288 ChemDiv1_003502 CCOC(=O)c1c(NC(=O)c2cc3cc(Br)ccc3oc2=O)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P05 compound treatment 562247.0 50100.0 0.22 571414.0 -1900.0 -0.01 0.1518 0.6768 1151055 ChemDiv1_003503 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P06 compound treatment 586439.0 74300.0 0.33 591429.0 18100.0 0.09 0.2985 0.8669 1381848 ChemDiv1_003504 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccccc5c4=O)C(=O)CC(C)(C)C3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P07 compound treatment 566193.0 54000.0 0.24 599258.0 25900.0 0.13 0.2619 0.9563 1972044 ChemDiv1_003505 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P08 compound treatment 582999.0 70800.0 0.32 606158.0 32800.0 0.16 0.3392 0.9519 1972045 ChemDiv1_003506 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P09 compound treatment 596825.0 84600.0 0.38 591705.0 18400.0 0.09 0.3324 0.8528 1467938 ChemDiv1_003507 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P10 compound treatment 588378.0 76200.0 0.34 599648.0 26300.0 0.13 0.3334 0.913 1611605 ChemDiv1_003508 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3cccc(Oc4ccccc4)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P11 compound treatment 587776.0 75600.0 0.34 600376.0 27100.0 0.13 0.3341 0.9178 1972046 ChemDiv1_003509 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P12 compound treatment 598725.0 86500.0 0.39 606231.0 32900.0 0.16 0.3893 0.926 1686944 ChemDiv1_003510 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P13 compound treatment 600622.0 88400.0 0.4 600780.0 27500.0 0.14 0.3762 0.8985 1736462 ChemDiv1_003511 COC(=O)CN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P14 compound treatment 577192.0 65000.0 0.29 605220.0 31900.0 0.16 0.3176 0.9588 1972047 ChemDiv1_003512 O=C(CSc1ncn[nH]1)NC2CCCCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P15 compound treatment 597606.0 85400.0 0.38 610577.0 37300.0 0.18 0.4009 0.9442 1278413 ChemDiv1_003513 Cc1cc(C)n(n1)c2cc(C)nc(NS(=O)(=O)c3ccccc3Cl)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P16 compound treatment 596427.0 84300.0 0.38 608514.0 35200.0 0.17 0.39 0.9386 1972048 ChemDiv1_003514 CC(C)OCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P17 compound treatment 590821.0 78600.0 0.35 627094.0 53800.0 0.27 0.4373 0.9905 1972049 ChemDiv1_003515 CCNc1nc(NC(C)C)nc(OCCOC(=O)c2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P18 compound treatment 586582.0 74400.0 0.33 634785.0 61500.0 0.3 0.4508 0.999 1124611 ChemDiv1_003516 O=C(N1N=C(CC1c2ccc3OCOc3c2)c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P19 compound treatment 576874.0 64700.0 0.29 596825.0 23500.0 0.12 0.2871 0.9199 1972050 ChemDiv1_003517 CCNc1nc(NC(C)C)nc(SCCOc2ccc(C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P20 compound treatment 582573.0 70400.0 0.32 614263.0 40900.0 0.2 0.3663 0.9773 1157509 ChemDiv1_003518 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(OCc3ccccc3)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P21 compound treatment 573278.0 61100.0 0.27 606589.0 33300.0 0.16 0.31 0.9706 1568401 ChemDiv1_003519 COc1cc(C)nc(n1)N(Cc2ccccc2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P22 compound treatment 566768.0 54600.0 0.24 598666.0 25400.0 0.13 0.2616 0.9521 1972051 ChemDiv1_003520 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(F)cc3)C)ccc1OCc4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P23 mock treatment 552280.0 40100.0 0.18 586703.0 13400.0 0.07 0.1738 0.9083 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.596 P24 mock treatment 436656.0 -75500.0 -0.34 220903.0 -352000.0 -1.75 -1.4735 -0.8286 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A01 compound treatment 971024.0 359000.0 1.61 916684.0 355000.0 1.76 2.3792 0.999 1972052 ChemDiv1_003521 COC(=O)c1cccc(c1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A02 compound treatment 584701.0 -27200.0 -0.12 559498.0 -2450.0 -0.01 -0.0948 -0.7736 1972053 ChemDiv1_003522 OCCN1CCN(CC1)c2ccc(cc2n3nc(c4ccccc4)c5ccccc5c3=O)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A03 compound treatment 603063.0 -8870.0 -0.04 570296.0 8350.0 0.04 0.0012 0.0204 1972054 ChemDiv1_003523 [O-][N+](=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A04 compound treatment 591024.0 -20900.0 -0.09 573370.0 11400.0 0.06 -0.0262 -0.2392 1972055 ChemDiv1_003524 CN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccc(cc4)C(C)(C)C)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A05 compound treatment 604999.0 -6940.0 -0.03 585880.0 23900.0 0.12 0.0619 0.5049 1972056 ChemDiv1_003525 CC1CCC2C(C1)C(=O)N(C2=O)c3cc(Cl)ccc3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A06 compound treatment 610918.0 -1020.0 0.0 618937.0 57000.0 0.28 0.1964 0.6956 1141663 ChemDiv1_003526 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A07 compound treatment 642282.0 30300.0 0.14 630360.0 68400.0 0.34 0.3357 0.9194 1972057 ChemDiv1_003527 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(s4)[N+](=O)[O-])C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A08 compound treatment 639057.0 27100.0 0.12 637756.0 75800.0 0.38 0.3514 0.8903 1972058 ChemDiv1_003528 [O-][N+](=O)c1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A09 compound treatment 654859.0 42900.0 0.19 630933.0 69000.0 0.34 0.3775 0.9629 1360827 ChemDiv1_003529 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccnc4)C(=O)Cc5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A10 compound treatment 657680.0 45700.0 0.2 636406.0 74500.0 0.37 0.4056 0.9614 1407185 ChemDiv1_003530 COc1cc(cc(OC)c1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A11 compound treatment 638507.0 26600.0 0.12 643189.0 81200.0 0.4 0.3687 0.8785 1972059 ChemDiv1_003531 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(cc4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A12 compound treatment 624033.0 12100.0 0.05 652079.0 90100.0 0.45 0.354 0.7871 1483635 ChemDiv1_003532 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A13 compound treatment 636994.0 25100.0 0.11 663113.0 101000.0 0.5 0.4337 0.8445 1741790 ChemDiv1_003533 CCOc1cc(ccc1O)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A14 compound treatment 637828.0 25900.0 0.12 644577.0 82600.0 0.41 0.3714 0.873 1972060 ChemDiv1_003534 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A15 compound treatment 651943.0 40000.0 0.18 650812.0 88900.0 0.44 0.4379 0.9214 1310272 ChemDiv1_003535 COc1ccccc1C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A16 compound treatment 631239.0 19300.0 0.09 637516.0 75600.0 0.37 0.3258 0.848 1947838 ChemDiv1_003536 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A17 compound treatment 656486.0 44600.0 0.2 636586.0 74600.0 0.37 0.4025 0.958 1972061 ChemDiv1_003537 COc1ccc(cc1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A18 compound treatment 638524.0 26600.0 0.12 639956.0 78000.0 0.39 0.3574 0.8839 1187227 ChemDiv1_003538 COc1ccc(cc1)C2=NN(C(C2)c3ccc(OC)c(OC)c3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A19 compound treatment 649590.0 37700.0 0.17 620984.0 59000.0 0.29 0.326 0.9657 1691001 ChemDiv1_003539 COc1cccc(c1)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A20 compound treatment 622309.0 10400.0 0.05 601893.0 39900.0 0.2 0.1728 0.85 1602615 ChemDiv1_003540 Cc1nc2sc(C(=O)c3ccc(Br)cc3)c(N)c2c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A21 compound treatment 631933.0 20000.0 0.09 589057.0 27100.0 0.13 0.1583 0.9806 1972062 ChemDiv1_003541 CN1C(=C(C(NC1=O)c2ccccc2C(F)(F)F)C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A22 compound treatment 600889.0 -11000.0 -0.05 570677.0 8730.0 0.04 -0.0044 -0.0666 1972063 ChemDiv1_003542 Fc1ccc(cc1)c2nn3c(nnc3s2)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A23 mock treatment 603247.0 -8690.0 -0.04 559865.0 -2080.0 -0.01 -0.0348 -0.8646 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 A24 mock treatment 217051.0 -395000.0 -1.77 501124.0 -60800.0 -0.3 -1.463 -0.8159 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B01 compound treatment 637107.0 25200.0 0.11 585610.0 23700.0 0.12 0.1626 0.9998 1478825 ChemDiv1_003543 CC1(C)Cc2c(C#N)c(SCC(=O)c3ccccc3)nc(N4CCOCC4)c2CO1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B02 compound treatment 1886124.0 1270000.0 5.7 1512691.0 951000.0 4.71 7.3635 0.9955 1730423 ChemDiv1_003544 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B03 compound treatment 738221.0 126000.0 0.57 682163.0 120000.0 0.6 0.8208 0.9997 1369892 ChemDiv1_003545 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B04 compound treatment 657891.0 46000.0 0.21 658093.0 96100.0 0.48 0.4823 0.9295 1600020 ChemDiv1_003546 COc1ccc(cc1Br)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B05 compound treatment 714198.0 102000.0 0.46 708060.0 146000.0 0.72 0.8355 0.9756 1323604 ChemDiv1_003547 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B06 compound treatment 700620.0 88700.0 0.4 677992.0 116000.0 0.57 0.6872 0.9837 1385707 ChemDiv1_003548 CC(C)(C)C1CCC(CC1)C(=O)On2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B07 compound treatment 728390.0 116000.0 0.52 727807.0 166000.0 0.82 0.9496 0.9759 1469351 ChemDiv1_003549 COc1cc(cc(OC)c1OC)C2Nc3cc(C)ccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B08 compound treatment 720513.0 109000.0 0.49 709763.0 148000.0 0.73 0.8615 0.9802 1972064 ChemDiv1_003550 CCOc1ccc(Br)cc1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B09 compound treatment 721402.0 109000.0 0.49 735110.0 173000.0 0.86 0.9531 0.9647 1374056 ChemDiv1_003551 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B10 compound treatment 726311.0 114000.0 0.51 741027.0 179000.0 0.89 0.9893 0.9659 1972065 ChemDiv1_003552 CCCC1=C(C(C(=C(N)O1)C#N)c2cccnc2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B11 compound treatment 725727.0 114000.0 0.51 742904.0 181000.0 0.9 0.9941 0.9641 1638651 ChemDiv1_003553 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccccn5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B12 compound treatment 720583.0 109000.0 0.49 695208.0 133000.0 0.66 0.8107 0.9887 1972066 ChemDiv1_003554 COC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B13 compound treatment 744590.0 133000.0 0.59 731922.0 170000.0 0.84 1.0153 0.9854 1454062 ChemDiv1_003555 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4c6ccc(F)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B14 compound treatment 727522.0 116000.0 0.52 716266.0 154000.0 0.76 0.9064 0.9819 1187408 ChemDiv1_003556 CCOc1ccc(cc1OCC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B15 compound treatment 776220.0 164000.0 0.74 759992.0 198000.0 0.98 1.2137 0.9899 1605039 ChemDiv1_003557 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B16 compound treatment 696077.0 84100.0 0.38 717747.0 156000.0 0.77 0.8121 0.9456 1972067 ChemDiv1_003558 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(cc3)C4C(=C(N)OC5=C4C(=O)CC(C)(C)C5)C#N)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B17 compound treatment 792277.0 180000.0 0.81 743729.0 182000.0 0.9 1.2076 0.9985 1508675 ChemDiv1_003559 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B18 compound treatment 727834.0 116000.0 0.52 695725.0 134000.0 0.66 0.8355 0.9927 1972068 ChemDiv1_003560 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B19 compound treatment 729436.0 118000.0 0.53 704272.0 142000.0 0.71 0.8705 0.9896 1972069 ChemDiv1_003561 COc1ccc(cc1COc2c(C)cccc2C)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B20 compound treatment 729358.0 117000.0 0.53 666393.0 104000.0 0.52 0.7375 1.0 1972070 ChemDiv1_003562 Cc1nn(c2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c12)N)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B21 compound treatment 881709.0 270000.0 1.21 825965.0 264000.0 1.31 1.7787 0.9992 1972071 ChemDiv1_003563 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B22 compound treatment 706335.0 94400.0 0.42 634105.0 72200.0 0.36 0.5516 0.9965 1371861 ChemDiv1_003564 CCOC(=O)C1=C(N)Oc2c(C1c3c(F)cccc3Cl)c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B23 mock treatment 713295.0 101000.0 0.45 641654.0 79700.0 0.39 0.6 0.9976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 B24 mock treatment 536644.0 -75300.0 -0.34 477454.0 -84500.0 -0.42 -0.5343 -0.9942 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C01 compound treatment 619748.0 7810.0 0.03 568502.0 6560.0 0.03 0.0477 0.9993 1783858 ChemDiv1_003565 [O-][N+](=O)c1c(Sc2ncnc3[nH]cnc23)ccc4nsnc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C02 compound treatment 650589.0 38700.0 0.17 601015.0 39100.0 0.19 0.2592 0.9984 1924205 ChemDiv1_003566 Cc1ccc(cc1C)c2nn(c3cc(ccc3[N+](=O)[O-])N4CCN(CCO)CC4)c(=O)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C03 compound treatment 684626.0 72700.0 0.33 654659.0 92700.0 0.46 0.5549 0.9858 1741741 ChemDiv1_003567 COc1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C04 compound treatment 671542.0 59600.0 0.27 658857.0 96900.0 0.48 0.5281 0.9616 1972072 ChemDiv1_003568 CC(C)(C)c1ccc(Oc2c(oc3cc(OCC(=O)O)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C05 compound treatment 704190.0 92300.0 0.41 686185.0 124000.0 0.62 0.7272 0.9812 1972073 ChemDiv1_003569 CC1CCC2C(C1)C(=O)N(CNc3ccc(Br)cc3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C06 compound treatment 691090.0 79200.0 0.35 694868.0 133000.0 0.66 0.7162 0.9577 1429536 ChemDiv1_003570 CCCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C07 compound treatment 687275.0 75300.0 0.34 692166.0 130000.0 0.65 0.6946 0.9542 1783502 ChemDiv1_003571 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(s4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C08 compound treatment 710548.0 98600.0 0.44 672060.0 110000.0 0.55 0.6979 0.9945 1972074 ChemDiv1_003572 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C09 compound treatment 717390.0 105000.0 0.47 722163.0 160000.0 0.79 0.895 0.9692 1333813 ChemDiv1_003573 CN(C)c1ccc(cc1)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C10 compound treatment 658934.0 47000.0 0.21 673007.0 111000.0 0.55 0.5378 0.913 1385408 ChemDiv1_003574 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C11 compound treatment 699057.0 87100.0 0.39 740873.0 179000.0 0.89 0.9025 0.932 1972075 ChemDiv1_003575 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C12 compound treatment 677193.0 65300.0 0.29 731365.0 169000.0 0.84 0.8 0.9003 1463317 ChemDiv1_003576 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C13 compound treatment 759274.0 147000.0 0.66 765273.0 203000.0 1.01 1.1786 0.9789 1972076 ChemDiv1_003577 CCCOc1cccc(c1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C14 compound treatment 733702.0 122000.0 0.55 719793.0 158000.0 0.78 0.9383 0.9844 1972077 ChemDiv1_003578 COc1ccc(cc1[N+](=O)[O-])C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C15 compound treatment 765487.0 154000.0 0.69 713744.0 152000.0 0.75 1.0178 0.999 1941658 ChemDiv1_003579 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C16 compound treatment 726092.0 114000.0 0.51 703061.0 141000.0 0.7 0.8557 0.9881 1972078 ChemDiv1_003580 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C17 compound treatment 753806.0 142000.0 0.64 723398.0 161000.0 0.8 1.0146 0.9935 1169887 ChemDiv1_003581 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccco3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C18 compound treatment 708565.0 96600.0 0.43 690175.0 128000.0 0.64 0.755 0.9825 1137529 ChemDiv1_003582 COc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C19 compound treatment 714214.0 102000.0 0.46 708461.0 147000.0 0.73 0.837 0.9753 1294475 ChemDiv1_003583 COc1ccc(C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C20 compound treatment 719127.0 107000.0 0.48 683642.0 122000.0 0.6 0.7656 0.9936 1972079 ChemDiv1_003584 Cc1cc(c(C#N)c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C21 compound treatment 703784.0 91800.0 0.41 681951.0 120000.0 0.59 0.7111 0.9838 1494965 ChemDiv1_003585 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C22 compound treatment 679812.0 67900.0 0.3 644113.0 82200.0 0.41 0.5027 0.9896 1972080 ChemDiv1_003586 Clc1ccc(cc1)c2nnc3sc(nn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C23 mock treatment 722488.0 111000.0 0.49 636725.0 74800.0 0.37 0.6119 0.9898 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 C24 mock treatment 471444.0 -140000.0 -0.63 498287.0 -63700.0 -0.32 -0.6677 -0.949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D01 compound treatment 642132.0 30200.0 0.14 596298.0 34400.0 0.17 0.2159 0.9935 1513188 ChemDiv1_003587 CC1(C)Cc2c(C#N)c(SCC(=O)c3ccc(Br)cc3)nc(N4CCOCC4)c2CO1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D02 compound treatment 671855.0 59900.0 0.27 588249.0 26300.0 0.13 0.2818 0.945 1949074 ChemDiv1_003588 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D03 compound treatment 696926.0 85000.0 0.38 673839.0 112000.0 0.55 0.661 0.9831 1972081 ChemDiv1_003589 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D04 compound treatment 700620.0 88700.0 0.4 661831.0 99900.0 0.49 0.6306 0.994 1289721 ChemDiv1_003590 Fc1ccccc1c2nc3ccccc3c(=O)n2OC(=O)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D05 compound treatment 736215.0 124000.0 0.56 709529.0 148000.0 0.73 0.9103 0.9909 1151856 ChemDiv1_003591 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D06 compound treatment 695569.0 83600.0 0.37 685975.0 124000.0 0.61 0.6992 0.9718 1634062 ChemDiv1_003592 Cc1cccc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4c(F)cccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D07 compound treatment 763728.0 152000.0 0.68 758988.0 197000.0 0.98 1.1707 0.9843 1273329 ChemDiv1_003593 Brc1cccc(c1)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D08 compound treatment 795392.0 183000.0 0.82 828639.0 267000.0 1.32 1.5149 0.9738 1121346 ChemDiv1_003594 CC1=C(C(C(=C(S)N1)C#N)c2cccs2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D09 compound treatment 741095.0 129000.0 0.58 751053.0 189000.0 0.94 1.0712 0.9731 1295486 ChemDiv1_003595 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D10 compound treatment 789941.0 178000.0 0.8 807994.0 246000.0 1.22 1.4253 0.9788 1972082 ChemDiv1_003596 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D11 compound treatment 776344.0 164000.0 0.74 727900.0 166000.0 0.82 1.1017 0.9985 1262591 ChemDiv1_003597 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccccc5F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D12 compound treatment 699528.0 87600.0 0.39 738340.0 176000.0 0.87 0.8951 0.9346 1972083 ChemDiv1_003598 CCCCOc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D13 compound treatment 736204.0 124000.0 0.56 758028.0 196000.0 0.97 1.0802 0.965 1420502 ChemDiv1_003599 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D14 compound treatment 760987.0 149000.0 0.67 725629.0 164000.0 0.81 1.0452 0.9953 1590080 ChemDiv1_003600 COc1cc(ccc1OC(C)C)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D15 compound treatment 794468.0 183000.0 0.82 772713.0 211000.0 1.04 1.3161 0.9926 1926561 ChemDiv1_003601 COc1ccc(cc1Cn2cc(cn2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D16 compound treatment 725148.0 113000.0 0.51 758552.0 197000.0 0.97 1.047 0.9537 1972084 ChemDiv1_003602 COc1ccc(cc1COc2ccccc2Br)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D17 compound treatment 784220.0 172000.0 0.77 760675.0 199000.0 0.98 1.2415 0.9927 1628129 ChemDiv1_003603 COc1ccc(cc1COc2cc(C)c(Cl)cc2C(C)C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D18 compound treatment 718511.0 107000.0 0.48 712411.0 150000.0 0.75 0.8644 0.9768 1972085 ChemDiv1_003604 COc1ccc(cc1COc2cccc(Cl)c2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D19 compound treatment 770363.0 158000.0 0.71 725023.0 163000.0 0.81 1.0727 0.9979 1293465 ChemDiv1_003605 COc1cc(cc(OC)c1OC)C2Nc3ccccc3C(=O)N2c4cccc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D20 compound treatment 739268.0 127000.0 0.57 704349.0 142000.0 0.71 0.9019 0.9944 1203913 ChemDiv1_003606 Cc1cc2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c2c(=O)o1)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D21 compound treatment 760112.0 148000.0 0.66 706753.0 145000.0 0.72 0.9763 0.9992 1403609 ChemDiv1_003607 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D22 compound treatment 749646.0 138000.0 0.62 696956.0 135000.0 0.67 0.9088 0.9992 1437882 ChemDiv1_003608 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D23 mock treatment 754247.0 142000.0 0.64 674522.0 113000.0 0.56 0.8448 0.9978 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 D24 mock treatment 532662.0 -79300.0 -0.35 481631.0 -80300.0 -0.4 -0.5322 -0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E01 compound treatment 650506.0 38600.0 0.17 611034.0 49100.0 0.24 0.294 0.9859 1913169 ChemDiv1_003609 COc1cc(cc(OC)c1OC)C2NC(Cc3c2[nH]c4ccccc34)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E02 compound treatment 640797.0 28900.0 0.13 621372.0 59400.0 0.29 0.2995 0.9317 1972086 ChemDiv1_003610 Cc1cc(C)n(n1)c2cc(C)nc(n2)n3nc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E03 compound treatment 698566.0 86600.0 0.39 670775.0 109000.0 0.54 0.6554 0.9869 1493314 ChemDiv1_003611 CCOC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E04 compound treatment 693520.0 81600.0 0.37 684199.0 122000.0 0.61 0.6865 0.9707 1267526 ChemDiv1_003612 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)COc3ccc4ccccc4c3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E05 compound treatment 703768.0 91800.0 0.41 681984.0 120000.0 0.59 0.7112 0.9837 1972087 ChemDiv1_003613 CC1CCC2C(C1)C(=O)N(CNc3ccc(Oc4ccc(Br)cc4)cc3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E06 compound treatment 686390.0 74500.0 0.33 712547.0 151000.0 0.75 0.7632 0.934 1463008 ChemDiv1_003614 CCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E07 compound treatment 690893.0 79000.0 0.35 727280.0 165000.0 0.82 0.8291 0.9294 1494841 ChemDiv1_003615 COc1cc(cc(OC)c1OC)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E08 compound treatment 724653.0 113000.0 0.5 728032.0 166000.0 0.82 0.9386 0.9724 1504968 ChemDiv1_003616 COc1ccc(Cl)cc1C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E09 compound treatment 731842.0 120000.0 0.54 746202.0 184000.0 0.91 1.025 0.968 1446706 ChemDiv1_003617 COc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E10 compound treatment 719106.0 107000.0 0.48 744660.0 183000.0 0.91 0.9793 0.9559 1386453 ChemDiv1_003618 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E11 compound treatment 745586.0 134000.0 0.6 773594.0 212000.0 1.05 1.1644 0.9646 1612209 ChemDiv1_003619 Cc1ccc(o1)C2N(C(=O)Cc3ccc(Cl)cc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E12 compound treatment 713648.0 102000.0 0.46 742546.0 181000.0 0.89 0.9546 0.9509 1618927 ChemDiv1_003620 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4c(F)cccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E13 compound treatment 753782.0 142000.0 0.63 721078.0 159000.0 0.79 1.0064 0.9942 1267036 ChemDiv1_003621 CCCOc1ccc(cc1OC)C2N(C(=O)CC)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E14 compound treatment 705533.0 93600.0 0.42 722120.0 160000.0 0.79 0.8573 0.9555 1207726 ChemDiv1_003622 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E15 compound treatment 748907.0 137000.0 0.61 782020.0 220000.0 1.09 1.2044 0.9629 1255600 ChemDiv1_003623 COc1cc(ccc1OCc2ccccc2)C3N(C(=O)C)c4ccccc4NC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E16 compound treatment 730358.0 118000.0 0.53 763661.0 202000.0 1.0 1.0814 0.956 1972088 ChemDiv1_003624 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E17 compound treatment 751218.0 139000.0 0.62 765212.0 203000.0 1.01 1.1529 0.9734 1972089 ChemDiv1_003625 CCCCCC(=O)N1C(C2=C(CC(CC2=O)c3ccco3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E18 compound treatment 723783.0 112000.0 0.5 724326.0 162000.0 0.8 0.9228 0.974 1675096 ChemDiv1_003626 Cc1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4o3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E19 compound treatment 726880.0 115000.0 0.51 748919.0 187000.0 0.93 1.0188 0.9615 1666247 ChemDiv1_003627 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E20 compound treatment 704148.0 92200.0 0.41 700691.0 139000.0 0.69 0.7779 0.9702 1463989 ChemDiv1_003628 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)N)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E21 compound treatment 737459.0 126000.0 0.56 722715.0 161000.0 0.8 0.9605 0.9854 1183030 ChemDiv1_003629 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Cl)c(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E22 compound treatment 710631.0 98700.0 0.44 685268.0 123000.0 0.61 0.7444 0.9873 1972090 ChemDiv1_003630 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E23 mock treatment 730363.0 118000.0 0.53 687025.0 125000.0 0.62 0.813 0.997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 E24 mock treatment 297022.0 -315000.0 -1.41 364871.0 -197000.0 -0.98 -1.6871 -0.9839 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F01 compound treatment 665528.0 53600.0 0.24 597383.0 35400.0 0.18 0.2938 0.9882 1641369 ChemDiv1_003631 CCOC(=O)c1sc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F02 compound treatment 768448.0 157000.0 0.7 676295.0 114000.0 0.57 0.896 0.9944 1641270 ChemDiv1_003632 CCOc1c(Br)cc(C=c2sc3nc4ccccc4n3c2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F03 compound treatment 709978.0 98000.0 0.44 632787.0 70800.0 0.35 0.5585 0.9939 1972091 ChemDiv1_003633 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F04 compound treatment 710276.0 98300.0 0.44 664919.0 103000.0 0.51 0.672 0.9973 1219588 ChemDiv1_003634 CC(C)(C)c1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F05 compound treatment 733690.0 122000.0 0.55 704869.0 143000.0 0.71 0.886 0.9916 1609774 ChemDiv1_003635 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F06 compound treatment 716181.0 104000.0 0.47 728433.0 166000.0 0.82 0.9132 0.9636 1685670 ChemDiv1_003636 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F07 compound treatment 753911.0 142000.0 0.64 731000.0 169000.0 0.84 1.0416 0.9907 1948397 ChemDiv1_003637 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F08 compound treatment 832170.0 220000.0 0.99 832106.0 270000.0 1.34 1.6434 0.9887 1622120 ChemDiv1_003638 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccsc2)S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F09 compound treatment 759006.0 147000.0 0.66 743271.0 181000.0 0.9 1.1007 0.9883 1972092 ChemDiv1_003639 COc1ccc(cc1COc2cc(C)c(Cl)cc2C(C)C)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F10 compound treatment 739256.0 127000.0 0.57 747342.0 185000.0 0.92 1.0524 0.9737 1972093 ChemDiv1_003640 COCCOC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F11 compound treatment 769773.0 158000.0 0.71 729254.0 167000.0 0.83 1.0857 0.9968 1623119 ChemDiv1_003641 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc5n(C)c6ccccc6c5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F12 compound treatment 738780.0 127000.0 0.57 763353.0 201000.0 1.0 1.107 0.9643 1972094 ChemDiv1_003642 Cc1nn(c(Cl)c1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F13 compound treatment 773705.0 162000.0 0.72 762738.0 201000.0 0.99 1.2154 0.9878 1533547 ChemDiv1_003643 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccc(F)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F14 compound treatment 678937.0 67000.0 0.3 715985.0 154000.0 0.76 0.7517 0.9168 1972095 ChemDiv1_003644 COCCOC(=O)C1=C(N)Oc2c(C1c3ccncc3)c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F15 compound treatment 796396.0 184000.0 0.83 766654.0 205000.0 1.01 1.3009 0.9948 1199095 ChemDiv1_003645 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F16 compound treatment 761534.0 150000.0 0.67 757902.0 196000.0 0.97 1.1599 0.9836 1972096 ChemDiv1_003646 COc1ccc(cc1COc2ccccc2[N+](=O)[O-])C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F17 compound treatment 812910.0 201000.0 0.9 776876.0 215000.0 1.06 1.389 0.9965 1554799 ChemDiv1_003647 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4Cc6ccco6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F18 compound treatment 758040.0 146000.0 0.65 717817.0 156000.0 0.77 1.0085 0.9966 1972097 ChemDiv1_003648 COc1ccc(cc1COc2ccc(Cl)cc2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F19 compound treatment 750025.0 138000.0 0.62 724458.0 163000.0 0.81 1.0064 0.9915 1210982 ChemDiv1_003649 CCN(CC)CCN1C(Nc2ccccc2C1=O)c3cc(OC)c(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F20 compound treatment 719691.0 108000.0 0.48 713807.0 152000.0 0.75 0.873 0.9769 1619977 ChemDiv1_003650 NC1=C(C#N)C2(C(=O)Nc3ccc(Br)cc32)C4=C(CCCC4=O)O1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F21 compound treatment 737335.0 125000.0 0.56 729474.0 168000.0 0.83 0.9838 0.9819 1503763 ChemDiv1_003651 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F22 compound treatment 727434.0 115000.0 0.52 672355.0 110000.0 0.55 0.7523 0.9996 1402798 ChemDiv1_003652 NS(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F23 mock treatment 722433.0 110000.0 0.49 687344.0 125000.0 0.62 0.789 0.9936 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 F24 mock treatment 537759.0 -74200.0 -0.33 496528.0 -65400.0 -0.32 -0.4639 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G01 compound treatment 642560.0 30600.0 0.14 589172.0 27200.0 0.13 0.1923 1.0 1323011 ChemDiv1_003653 Clc1ccc(cc1Cl)n2c(CSc3ncnc4[nH]cnc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G02 compound treatment 652653.0 40700.0 0.18 616288.0 54300.0 0.27 0.3192 0.982 1949436 ChemDiv1_003654 FC(F)(F)c1ccc(Cl)c(NC(=O)C2COc3ccccc3O2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G03 compound treatment 714309.0 102000.0 0.46 658308.0 96400.0 0.48 0.6616 0.9998 1972098 ChemDiv1_003655 CC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G04 compound treatment 694598.0 82700.0 0.37 647798.0 85900.0 0.43 0.5624 0.9976 1269765 ChemDiv1_003656 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G05 compound treatment 714579.0 103000.0 0.46 693445.0 132000.0 0.65 0.7855 0.9854 1531225 ChemDiv1_003657 COc1ccc(cc1)c2cc(C(=O)Nc3ccccc3OC)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G06 compound treatment 719949.0 108000.0 0.48 663971.0 102000.0 0.51 0.6993 0.9998 1972099 ChemDiv1_003658 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G07 compound treatment 730951.0 119000.0 0.53 719154.0 157000.0 0.78 0.9274 0.9829 1972100 ChemDiv1_003659 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G08 compound treatment 718281.0 106000.0 0.48 720756.0 159000.0 0.79 0.8929 0.971 1588762 ChemDiv1_003660 COc1cccc(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G09 compound treatment 753687.0 142000.0 0.63 712694.0 151000.0 0.75 0.9767 0.9967 1782662 ChemDiv1_003661 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccc(c4)[N+](=O)[O-])C(=O)Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G10 compound treatment 718715.0 107000.0 0.48 739409.0 177000.0 0.88 0.9596 0.959 1972101 ChemDiv1_003662 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(cc4Cl)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G11 compound treatment 732498.0 121000.0 0.54 741545.0 180000.0 0.89 1.0107 0.9713 1972102 ChemDiv1_003663 COc1cc(cc(OC)c1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G12 compound treatment 686585.0 74700.0 0.33 741967.0 180000.0 0.89 0.8669 0.9103 1972103 ChemDiv1_003664 COc1ccc(cc1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G13 compound treatment 751738.0 140000.0 0.63 729347.0 167000.0 0.83 1.0289 0.9904 1972104 ChemDiv1_003665 CCCOc1ccc(cc1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G14 compound treatment 741057.0 129000.0 0.58 761245.0 199000.0 0.99 1.1068 0.9675 1698962 ChemDiv1_003666 COc1ccc(cc1OC)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G15 compound treatment 761329.0 149000.0 0.67 788024.0 226000.0 1.12 1.2648 0.9696 1972105 ChemDiv1_003667 CC(C)Oc1ccc(cc1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G16 compound treatment 720938.0 109000.0 0.49 744240.0 182000.0 0.9 0.9836 0.9582 1289089 ChemDiv1_003668 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G17 compound treatment 753412.0 141000.0 0.63 761095.0 199000.0 0.99 1.1454 0.977 1972106 ChemDiv1_003669 COc1ccc(cc1OC)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G18 compound treatment 716787.0 105000.0 0.47 698277.0 136000.0 0.68 0.8094 0.9842 1328822 ChemDiv1_003670 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)cc(C)c3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G19 compound treatment 733429.0 121000.0 0.54 718586.0 157000.0 0.78 0.9333 0.9849 1947407 ChemDiv1_003671 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G20 compound treatment 774301.0 162000.0 0.73 812485.0 251000.0 1.24 1.3915 0.9675 1332142 ChemDiv1_003672 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G21 compound treatment 713311.0 101000.0 0.45 618064.0 56100.0 0.28 0.5175 0.9723 1947503 ChemDiv1_003673 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(Cl)c(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G22 compound treatment 712442.0 101000.0 0.45 681459.0 120000.0 0.59 0.7368 0.9908 1332974 ChemDiv1_003674 COC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G23 mock treatment 718266.0 106000.0 0.48 675349.0 113000.0 0.56 0.7338 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 G24 mock treatment 188010.0 -424000.0 -1.9 533265.0 -28700.0 -0.14 -1.4423 -0.7579 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H01 compound treatment 661245.0 49300.0 0.22 594732.0 32800.0 0.16 0.2709 0.9886 1972107 ChemDiv1_003675 CCOC(=O)c1c(NC(=O)CN2C(=O)C3CC=C(Cl)CC3C2=O)sc4CCCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H02 compound treatment 685327.0 73400.0 0.33 627482.0 65500.0 0.32 0.4619 1.0 1138082 ChemDiv1_003676 COc1ccc(cc1)C(=O)Oc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H03 compound treatment 725808.0 114000.0 0.51 673482.0 112000.0 0.55 0.7511 0.9992 1597317 ChemDiv1_003677 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H04 compound treatment 704231.0 92300.0 0.41 627592.0 65600.0 0.33 0.5221 0.993 1972108 ChemDiv1_003678 Cc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H05 compound treatment 710155.0 98200.0 0.44 704585.0 143000.0 0.71 0.8105 0.9739 1972109 ChemDiv1_003679 COc1ccc(/C=C(\C#N)/C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H06 compound treatment 728241.0 116000.0 0.52 707733.0 146000.0 0.72 0.8788 0.9871 1275145 ChemDiv1_003680 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)nc(OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H07 compound treatment 729960.0 118000.0 0.53 722368.0 160000.0 0.79 0.9355 0.9803 1972110 ChemDiv1_003681 CSc1nnc(o1)c2ccc(NC(=S)N3CCCCC3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H08 compound treatment 1061573.0 450000.0 2.01 1089061.0 527000.0 2.61 3.2696 0.9917 1294556 ChemDiv1_003682 CC1=C(C(C(=C(S)N1)C#N)c2cccnc2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H09 compound treatment 751844.0 140000.0 0.63 754289.0 192000.0 0.95 1.1166 0.9793 1631992 ChemDiv1_003683 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H10 compound treatment 750136.0 138000.0 0.62 742281.0 180000.0 0.89 1.0691 0.9839 1972111 ChemDiv1_003684 COCCOC(=O)C1=C(N)OC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H11 compound treatment 763565.0 152000.0 0.68 764358.0 202000.0 1.0 1.189 0.9819 1304978 ChemDiv1_003685 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H12 compound treatment 729050.0 117000.0 0.52 739115.0 177000.0 0.88 0.9913 0.9697 1972112 ChemDiv1_003686 Cc1nn(c(Cl)c1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H13 compound treatment 734104.0 122000.0 0.55 778594.0 217000.0 1.07 1.1456 0.9511 1738017 ChemDiv1_003687 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccc(Cl)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H14 compound treatment 1337913.0 726000.0 3.25 1686670.0 1120000.0 5.57 6.2377 0.9671 1972113 ChemDiv1_003688 Cc1cc(c2c(N)c(sc2n1)C(=O)c3ccc(Cl)s3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H15 compound treatment 767690.0 156000.0 0.7 759801.0 198000.0 0.98 1.1861 0.9861 1506926 ChemDiv1_003689 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4c6ccc(C)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H16 compound treatment 735609.0 124000.0 0.55 747139.0 185000.0 0.92 1.0402 0.9708 1972114 ChemDiv1_003690 COc1ccc(cc1COc2ccccc2[N+](=O)[O-])C3C(=C(N)Oc4n[nH]c(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H17 compound treatment 732433.0 120000.0 0.54 769981.0 208000.0 1.03 1.1101 0.9544 1741585 ChemDiv1_003691 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H18 compound treatment 707359.0 95400.0 0.43 737887.0 176000.0 0.87 0.9183 0.9461 1972115 ChemDiv1_003692 COC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H19 compound treatment 780635.0 169000.0 0.76 739176.0 177000.0 0.88 1.1548 0.9972 1585328 ChemDiv1_003693 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(CSc4ccccn4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H20 compound treatment 746399.0 134000.0 0.6 712285.0 150000.0 0.74 0.9522 0.9944 1972116 ChemDiv1_003694 COc1ccc(NC(=O)CSc2nc(C)cc(c2C#N)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H21 compound treatment 855427.0 243000.0 1.09 839147.0 277000.0 1.37 1.7417 0.9935 1940201 ChemDiv1_003695 Oc1ccccc1C2CC(=NN2c3ccc(cc3)[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H22 compound treatment 735861.0 124000.0 0.55 705781.0 144000.0 0.71 0.8961 0.9923 1783090 ChemDiv1_003696 OC(=O)CCc1nc2ccccc2[nH]c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H23 mock treatment 723843.0 112000.0 0.5 671607.0 110000.0 0.54 0.7384 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 H24 mock treatment 529435.0 -82500.0 -0.37 187968.0 -374000.0 -1.85 -1.5711 -0.8317 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I01 compound treatment 624739.0 12800.0 0.06 578649.0 16700.0 0.08 0.099 0.9839 1972117 ChemDiv1_003697 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4cccc5cccnc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I02 compound treatment 677940.0 66000.0 0.3 609717.0 47800.0 0.24 0.3763 0.9939 1942266 ChemDiv1_003698 FC(F)(F)c1ccc(Cl)c(NC(=O)CCN2C(=O)c3ccccc3C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I03 compound treatment 707510.0 95600.0 0.43 648228.0 86300.0 0.43 0.6048 1.0 1398617 ChemDiv1_003699 Brc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I04 compound treatment 685819.0 73900.0 0.33 663674.0 102000.0 0.5 0.5902 0.9791 1117622 ChemDiv1_003700 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I05 compound treatment 708762.0 96800.0 0.43 670087.0 108000.0 0.54 0.6853 0.9945 1735688 ChemDiv1_003701 CN(C)c1ccc(cc1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I06 compound treatment 689056.0 77100.0 0.35 655603.0 93700.0 0.46 0.5722 0.9894 1972118 ChemDiv1_003702 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I07 compound treatment 697596.0 85700.0 0.38 699462.0 138000.0 0.68 0.7528 0.963 1686952 ChemDiv1_003703 COc1cc(cc(OC)c1OC)C2N(C(=O)C(C)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I08 compound treatment 735374.0 123000.0 0.55 714976.0 153000.0 0.76 0.9268 0.9879 1149956 ChemDiv1_003704 COc1cc(OC)cc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I09 compound treatment 691352.0 79400.0 0.36 710930.0 149000.0 0.74 0.7733 0.9439 1947742 ChemDiv1_003705 CN(C)/C=C\1/C(=O)N(N=C1C(F)(F)F)c2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I10 compound treatment 703610.0 91700.0 0.41 701802.0 140000.0 0.69 0.7801 0.9688 1972119 ChemDiv1_003706 COc1ccc(C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I11 compound treatment 734925.0 123000.0 0.55 730861.0 169000.0 0.84 0.981 0.9794 1488499 ChemDiv1_003707 CN(C)c1ccc(cc1)C2N(C(=O)c3ccc(F)cc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I12 compound treatment 722931.0 111000.0 0.5 707712.0 146000.0 0.72 0.8619 0.9834 1712333 ChemDiv1_003708 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I13 compound treatment 740959.0 129000.0 0.58 744688.0 183000.0 0.91 1.0485 0.9764 1152977 ChemDiv1_003709 COc1ccc(OC)c(c1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I14 compound treatment 703373.0 91400.0 0.41 742316.0 180000.0 0.89 0.9212 0.9374 1166729 ChemDiv1_003710 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I15 compound treatment 754855.0 143000.0 0.64 749885.0 188000.0 0.93 1.1107 0.9832 1640599 ChemDiv1_003711 CC(=O)Oc1cccc(c1)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I16 compound treatment 849851.0 238000.0 1.07 903178.0 341000.0 1.69 1.9484 0.9752 1972120 ChemDiv1_003712 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I17 compound treatment 735581.0 124000.0 0.55 739040.0 177000.0 0.88 1.0117 0.9753 1425826 ChemDiv1_003713 CCN(CC)c1ccc(cc1)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I18 compound treatment 727489.0 116000.0 0.52 726723.0 165000.0 0.82 0.943 0.9758 1218259 ChemDiv1_003714 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(ccc3C#N)C4CC4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I19 compound treatment 751240.0 139000.0 0.62 715145.0 153000.0 0.76 0.9776 0.9952 1972121 ChemDiv1_003715 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(ccc5Cl)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I20 compound treatment 713305.0 101000.0 0.45 737781.0 176000.0 0.87 0.9368 0.9538 1338023 ChemDiv1_003716 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I21 compound treatment 734137.0 122000.0 0.55 715549.0 154000.0 0.76 0.9249 0.9869 1948370 ChemDiv1_003717 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I22 compound treatment 704041.0 92100.0 0.41 674999.0 113000.0 0.56 0.6876 0.9887 1259634 ChemDiv1_003718 COC(=O)CCSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I23 mock treatment 719149.0 107000.0 0.48 662549.0 101000.0 0.5 0.6918 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 I24 mock treatment 204624.0 -407000.0 -1.82 487116.0 -74800.0 -0.37 -1.5514 -0.8338 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J01 compound treatment 650277.0 38300.0 0.17 602104.0 40200.0 0.2 0.262 0.9973 1530128 ChemDiv1_003719 CCN(CC)c1ccc(cc1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J02 compound treatment 693300.0 81400.0 0.36 634995.0 73100.0 0.36 0.5134 1.0 1972122 ChemDiv1_003720 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J03 compound treatment 740538.0 129000.0 0.58 649966.0 88000.0 0.44 0.7154 0.9906 1972123 ChemDiv1_003721 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J04 compound treatment 696428.0 84500.0 0.38 638326.0 76400.0 0.38 0.535 1.0 1506469 ChemDiv1_003722 Cc1cccc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J05 compound treatment 739239.0 127000.0 0.57 710590.0 149000.0 0.74 0.9236 0.992 1291803 ChemDiv1_003723 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccoc3)c4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J06 compound treatment 720685.0 109000.0 0.49 714997.0 153000.0 0.76 0.8803 0.9771 1528862 ChemDiv1_003724 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J07 compound treatment 729314.0 117000.0 0.53 740055.0 178000.0 0.88 0.9954 0.9693 1654231 ChemDiv1_003725 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N)C(=O)N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J08 compound treatment 730568.0 119000.0 0.53 730762.0 169000.0 0.84 0.9669 0.976 1348892 ChemDiv1_003726 NC1=C(C#N)C(c2cccc(OCc3ccccc3)c2)c4c(O1)c5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J09 compound treatment 758928.0 147000.0 0.66 754654.0 193000.0 0.95 1.1403 0.9835 1117948 ChemDiv1_003727 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J10 compound treatment 766897.0 155000.0 0.69 774059.0 212000.0 1.05 1.2335 0.9797 1972124 ChemDiv1_003728 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3[N+](=O)[O-])C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J11 compound treatment 759676.0 148000.0 0.66 728934.0 167000.0 0.83 1.0526 0.9938 1583931 ChemDiv1_003729 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J12 compound treatment 754319.0 142000.0 0.64 733183.0 171000.0 0.85 1.0505 0.9901 1180588 ChemDiv1_003730 COc1cc(ccc1OCC(=O)N)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J13 compound treatment 744538.0 133000.0 0.59 763625.0 202000.0 1.0 1.1262 0.9691 1419738 ChemDiv1_003731 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J14 compound treatment 798499.0 187000.0 0.84 789889.0 228000.0 1.13 1.389 0.989 1972125 ChemDiv1_003732 COc1ccc(/C=C/2\CN(C)CC3=C2OC(=C(C#N)C3c4ccc(OC)c(OC)c4)N)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J15 compound treatment 753693.0 142000.0 0.63 738667.0 177000.0 0.88 1.0677 0.9875 1189649 ChemDiv1_003733 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J16 compound treatment 767617.0 156000.0 0.7 746931.0 185000.0 0.92 1.1408 0.9909 1296335 ChemDiv1_003734 COc1ccc(cc1COc2cccc(Cl)c2)C3C(=C(N)Oc4n[nH]c(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J17 compound treatment 767837.0 156000.0 0.7 733881.0 172000.0 0.85 1.0957 0.9951 1972126 ChemDiv1_003735 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J18 compound treatment 735093.0 123000.0 0.55 739647.0 178000.0 0.88 1.0123 0.9746 1257070 ChemDiv1_003736 CCN(CC)C(=O)COc1ccc(cc1OC)C2C(=C(N)Oc3n[nH]c(COC)c23)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J19 compound treatment 739352.0 127000.0 0.57 733651.0 172000.0 0.85 1.0048 0.9811 1932003 ChemDiv1_003737 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc([N+](=O)[O-])c(C)c4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J20 compound treatment 653803.0 41900.0 0.19 661699.0 99800.0 0.49 0.482 0.9119 1972127 ChemDiv1_003738 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J21 compound treatment 730159.0 118000.0 0.53 756252.0 194000.0 0.96 1.0548 0.9603 1454491 ChemDiv1_003739 Cn1c(nc2ccccc12)n3c(CN4C(=O)c5ccccc5C4=O)nc6ccccc6c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J22 compound treatment 715952.0 104000.0 0.47 715767.0 154000.0 0.76 0.8681 0.9721 1329005 ChemDiv1_003740 CS(=O)(=O)Cc1nc2ccccc2[nH]c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J23 mock treatment 730352.0 118000.0 0.53 689471.0 128000.0 0.63 0.8215 0.9962 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 J24 mock treatment 326890.0 -285000.0 -1.28 483672.0 -78300.0 -0.39 -1.1764 -0.8822 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K01 compound treatment 626223.0 14300.0 0.06 578722.0 16800.0 0.08 0.104 0.9916 1972128 ChemDiv1_003741 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K02 compound treatment 670598.0 58700.0 0.26 615434.0 53500.0 0.26 0.3731 1.0 1513122 ChemDiv1_003742 CC1CCc2c(C(=O)N)c(NC(=O)CCN3C(=O)c4ccccc4C3=O)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K03 compound treatment 698050.0 86100.0 0.39 655122.0 93200.0 0.46 0.599 0.996 1972129 ChemDiv1_003743 COc1ccc(cc1)c2cc(C(=O)Nc3cccc(c3)C(=O)C)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K04 compound treatment 677635.0 65700.0 0.29 646677.0 84700.0 0.42 0.5048 0.9849 1551904 ChemDiv1_003744 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K05 compound treatment 721618.0 110000.0 0.49 679635.0 118000.0 0.58 0.7594 0.9963 1479033 ChemDiv1_003745 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K06 compound treatment 705013.0 93100.0 0.42 674669.0 113000.0 0.56 0.6895 0.9896 1972130 ChemDiv1_003746 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K07 compound treatment 736210.0 124000.0 0.56 705394.0 143000.0 0.71 0.8958 0.9927 1213027 ChemDiv1_003747 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccs4)C(=O)Cc5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K08 compound treatment 711228.0 99300.0 0.44 685893.0 124000.0 0.61 0.7485 0.9874 1389135 ChemDiv1_003748 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(F)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K09 compound treatment 725842.0 114000.0 0.51 703979.0 142000.0 0.7 0.8581 0.9875 1972131 ChemDiv1_003749 CN(C)/C=C\1/C(=O)N(N=C1c2ccccc2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K10 compound treatment 718014.0 106000.0 0.47 709034.0 147000.0 0.73 0.851 0.9785 1552821 ChemDiv1_003750 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K11 compound treatment 745608.0 134000.0 0.6 738199.0 176000.0 0.87 1.0405 0.983 1972132 ChemDiv1_003751 CCCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cccc(OC)c4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K12 compound treatment 720573.0 109000.0 0.49 684787.0 123000.0 0.61 0.7742 0.9938 1496326 ChemDiv1_003752 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K13 compound treatment 756506.0 145000.0 0.65 710406.0 148000.0 0.74 0.9776 0.998 1972133 ChemDiv1_003753 CCCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K14 compound treatment 741466.0 130000.0 0.58 678140.0 116000.0 0.58 0.817 1.0 1972134 ChemDiv1_003754 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K15 compound treatment 740005.0 128000.0 0.57 742425.0 180000.0 0.89 1.0376 0.9769 1373102 ChemDiv1_003755 COc1ccc(cc1COc2ccc(F)cc2)C3N(C(=O)C)c4ccccc4NC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K16 compound treatment 735418.0 123000.0 0.55 713506.0 152000.0 0.75 0.9218 0.9887 1352004 ChemDiv1_003756 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K17 compound treatment 754064.0 142000.0 0.64 720793.0 159000.0 0.79 1.0063 0.9944 1719199 ChemDiv1_003757 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)c(OC)c5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K18 compound treatment 764940.0 153000.0 0.68 727045.0 165000.0 0.82 1.0626 0.9961 1412842 ChemDiv1_003758 COc1cc(cc(OC)c1OC)c2cc(nc3sc(C(=O)O)c(N)c23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K19 compound treatment 725361.0 113000.0 0.51 707095.0 145000.0 0.72 0.8675 0.9855 1947628 ChemDiv1_003759 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K20 compound treatment 730878.0 119000.0 0.53 692454.0 131000.0 0.65 0.8336 0.9954 1972135 ChemDiv1_003760 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c(C)c(C)c3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K21 compound treatment 712673.0 101000.0 0.45 660865.0 98900.0 0.49 0.6654 0.9991 1947607 ChemDiv1_003761 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K22 compound treatment 693704.0 81800.0 0.37 670859.0 109000.0 0.54 0.6403 0.9821 1559240 ChemDiv1_003762 CC1(C)Cc2c(CS1)c(nc3sc(C(=O)c4ccccc4)c(N)c23)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K23 mock treatment 715819.0 104000.0 0.47 670058.0 108000.0 0.54 0.7075 0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 K24 mock treatment 504013.0 -108000.0 -0.48 449952.0 -112000.0 -0.55 -0.7339 -0.9976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L01 compound treatment 653400.0 41500.0 0.19 605151.0 43200.0 0.21 0.2826 0.9975 1972136 ChemDiv1_003763 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L02 compound treatment 674593.0 62700.0 0.28 626074.0 64100.0 0.32 0.423 0.9981 1169379 ChemDiv1_003764 CCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L03 compound treatment 712168.0 100000.0 0.45 670528.0 109000.0 0.54 0.6976 0.9959 1166341 ChemDiv1_003765 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L04 compound treatment 702278.0 90300.0 0.4 658790.0 96800.0 0.48 0.6252 0.9964 1470873 ChemDiv1_003766 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2OC(=O)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L05 compound treatment 717934.0 106000.0 0.47 713011.0 151000.0 0.75 0.8647 0.9758 1278030 ChemDiv1_003767 COc1ccc(cc1OC)C2N(C(=O)C(C)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L06 compound treatment 695800.0 83900.0 0.38 657720.0 95800.0 0.47 0.6009 0.9933 1512237 ChemDiv1_003768 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L07 compound treatment 739057.0 127000.0 0.57 724131.0 162000.0 0.8 0.9705 0.9857 1657300 ChemDiv1_003769 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L08 compound treatment 713680.0 102000.0 0.46 691085.0 129000.0 0.64 0.7744 0.9861 1972137 ChemDiv1_003770 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L09 compound treatment 734237.0 122000.0 0.55 730901.0 169000.0 0.84 0.979 0.9788 1326813 ChemDiv1_003771 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(CSc5nc6ccccc6s5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L10 compound treatment 727565.0 116000.0 0.52 689106.0 127000.0 0.63 0.8114 0.9952 1972138 ChemDiv1_003772 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L11 compound treatment 765060.0 153000.0 0.69 747683.0 186000.0 0.92 1.1353 0.9895 1972139 ChemDiv1_003773 COc1ccc(cc1Cn2nc(C)c([N+](=O)[O-])c2C)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L12 compound treatment 737065.0 125000.0 0.56 723930.0 162000.0 0.8 0.9635 0.9846 1972140 ChemDiv1_003774 NC1=C(C#N)C(c2ccc(F)cc2Br)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L13 compound treatment 727560.0 116000.0 0.52 711544.0 150000.0 0.74 0.89 0.9846 1637737 ChemDiv1_003775 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L14 compound treatment 797396.0 185000.0 0.83 772181.0 210000.0 1.04 1.3235 0.9937 1224452 ChemDiv1_003776 CC1=C(C(C(=C(S)N1)C#N)c2ccsc2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L15 compound treatment 740521.0 129000.0 0.58 745902.0 184000.0 0.91 1.0514 0.9754 1972141 ChemDiv1_003777 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L16 compound treatment 757879.0 146000.0 0.65 721143.0 159000.0 0.79 1.0196 0.9956 1972142 ChemDiv1_003778 COc1ccc(cc1Cn2nc([N+](=O)[O-])c(Br)c2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L17 compound treatment 757986.0 146000.0 0.65 740174.0 178000.0 0.88 1.0866 0.9891 1972143 ChemDiv1_003779 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4c6cccc7ccccc67 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L18 compound treatment 713280.0 101000.0 0.45 706608.0 145000.0 0.72 0.8275 0.9757 1633285 ChemDiv1_003780 CCN(CC)C(=O)COc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L19 compound treatment 725460.0 114000.0 0.51 692718.0 131000.0 0.65 0.8174 0.9928 1972144 ChemDiv1_003781 CCN(CC)C(=O)CN1C(=O)C2CCC(=O)CC2C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L20 compound treatment 733953.0 122000.0 0.55 693474.0 132000.0 0.65 0.847 0.9962 1972145 ChemDiv1_003782 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L21 compound treatment 740328.0 128000.0 0.57 709330.0 147000.0 0.73 0.9227 0.993 1402136 ChemDiv1_003783 COc1ccccc1n2c(CCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L22 compound treatment 741232.0 129000.0 0.58 707069.0 145000.0 0.72 0.9176 0.9942 1315025 ChemDiv1_003784 Oc1ccc(cc1)C2Nc3ccc4ccccc4c3C5C=CCC52 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L23 mock treatment 723761.0 112000.0 0.5 676684.0 115000.0 0.57 0.7559 0.998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 L24 mock treatment 305073.0 -307000.0 -1.37 527550.0 -34400.0 -0.17 -1.0918 -0.7888 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M01 compound treatment 648542.0 36600.0 0.16 568174.0 6230.0 0.03 0.1377 0.8258 1949666 ChemDiv1_003785 CCOc1cc([N+](=O)[O-])c2NC(C3CC=CC3c2c1)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M02 compound treatment 661449.0 49500.0 0.22 557865.0 -4080.0 -0.02 0.1424 0.64 1972146 ChemDiv1_003786 CCC(C)OC(=O)CSc1nc2ccccc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M03 compound treatment 705802.0 93900.0 0.42 638487.0 76500.0 0.38 0.5652 0.9987 1251151 ChemDiv1_003787 COc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M04 compound treatment 687779.0 75800.0 0.34 618500.0 56600.0 0.28 0.4382 0.9954 1947665 ChemDiv1_003788 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M05 compound treatment 701542.0 89600.0 0.4 645824.0 83900.0 0.42 0.5774 0.9998 1152342 ChemDiv1_003789 Clc1ccc2[nH]c(=O)c(Sc3nc4ccccc4o3)c(c5ccccc5)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M06 compound treatment 699315.0 87400.0 0.39 665051.0 103000.0 0.51 0.6378 0.9913 1972147 ChemDiv1_003790 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M07 compound treatment 732721.0 121000.0 0.54 685410.0 123000.0 0.61 0.8148 0.9981 1621548 ChemDiv1_003791 CCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M08 compound treatment 698071.0 86100.0 0.39 664717.0 103000.0 0.51 0.6326 0.9906 1440054 ChemDiv1_003792 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cc4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M09 compound treatment 714722.0 103000.0 0.46 681094.0 119000.0 0.59 0.7427 0.9924 1942532 ChemDiv1_003793 CN(C)/C=C/1\C(=O)N(N=C1c2ccccc2)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M10 compound treatment 727116.0 115000.0 0.52 667813.0 106000.0 0.52 0.7354 1.0 1972148 ChemDiv1_003794 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc([N+](=O)[O-])c(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M11 compound treatment 739216.0 127000.0 0.57 681796.0 120000.0 0.59 0.8227 0.9998 1972149 ChemDiv1_003795 COc1cccc(C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M12 compound treatment 712389.0 100000.0 0.45 681483.0 120000.0 0.59 0.7367 0.9908 1972150 ChemDiv1_003796 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M13 compound treatment 758839.0 147000.0 0.66 695970.0 134000.0 0.66 0.9345 1.0 1972151 ChemDiv1_003797 COc1ccc(OC)c(c1)C2N(C(=O)C(F)(F)F)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M14 compound treatment 718094.0 106000.0 0.48 705456.0 144000.0 0.71 0.8387 0.9808 1305534 ChemDiv1_003798 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M15 compound treatment 757986.0 146000.0 0.65 719401.0 157000.0 0.78 1.0138 0.9961 1972152 ChemDiv1_003799 CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(o4)c5ccc(cc5C)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M16 compound treatment 698905.0 87000.0 0.39 672201.0 110000.0 0.55 0.6615 0.9862 1214079 ChemDiv1_003800 OCCNc1nc(c2ccccc2)c3cc(Br)ccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M17 compound treatment 730746.0 119000.0 0.53 705276.0 143000.0 0.71 0.8781 0.9899 1972153 ChemDiv1_003801 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)c(OC)c5)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M18 compound treatment 751129.0 139000.0 0.62 679434.0 117000.0 0.58 0.8521 0.9994 1972154 ChemDiv1_003802 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)O)c2C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M19 compound treatment 739993.0 128000.0 0.57 694493.0 133000.0 0.66 0.8696 0.9977 1947347 ChemDiv1_003803 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)c(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M20 compound treatment 721990.0 110000.0 0.49 665643.0 104000.0 0.51 0.7116 0.9998 1972155 ChemDiv1_003804 Cc1ccc(cc1)N2C(=O)CC(Sc3nc(C)cc(c3C#N)C(F)(F)F)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M21 compound treatment 747521.0 136000.0 0.61 639930.0 78000.0 0.39 0.7023 0.9762 1244208 ChemDiv1_003805 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M22 compound treatment 729000.0 117000.0 0.52 658367.0 96400.0 0.48 0.7083 0.9989 1972156 ChemDiv1_003806 CC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M23 mock treatment 709889.0 98000.0 0.44 659159.0 97200.0 0.48 0.6506 0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 M24 mock treatment 584351.0 -27600.0 -0.12 282628.0 -279000.0 -1.38 -1.0657 -0.7672 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N01 compound treatment 645419.0 33500.0 0.15 586073.0 24100.0 0.12 0.1905 0.9937 1972157 ChemDiv1_003807 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N02 compound treatment 665676.0 53700.0 0.24 588874.0 26900.0 0.13 0.2644 0.9613 1565660 ChemDiv1_003808 Cc1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N03 compound treatment 719980.0 108000.0 0.48 664104.0 102000.0 0.51 0.6998 0.9997 1471743 ChemDiv1_003809 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(C)c(C)cc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N04 compound treatment 693251.0 81300.0 0.36 631156.0 69200.0 0.34 0.4998 0.9996 1442690 ChemDiv1_003810 COc1ccc(cc1Br)C(=O)On2c(nc3ccccc3c2=O)c4ccc(cc4)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N05 compound treatment 719900.0 108000.0 0.48 682259.0 120000.0 0.6 0.7632 0.9946 1950708 ChemDiv1_003811 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N06 compound treatment 694908.0 83000.0 0.37 678541.0 117000.0 0.58 0.6711 0.9772 1972158 ChemDiv1_003812 Fc1ccc(N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4sc5ccccc5c4Cl)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N07 compound treatment 731576.0 120000.0 0.54 702523.0 141000.0 0.7 0.8711 0.9916 1308177 ChemDiv1_003813 CCOC(=O)c1cnn(c1NC(=O)CSc2nc3ccc(OCC)cc3s2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N08 compound treatment 700666.0 88700.0 0.4 681898.0 120000.0 0.59 0.701 0.9808 1972159 ChemDiv1_003814 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N09 compound treatment 717598.0 106000.0 0.47 699864.0 138000.0 0.68 0.8176 0.9839 1206117 ChemDiv1_003815 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(COc5ccc(NC(=O)C)cc5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N10 compound treatment 683037.0 71100.0 0.32 705931.0 144000.0 0.71 0.7294 0.9339 1716002 ChemDiv1_003816 NC1=C(C#N)C(c2cccc(Br)c2)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N11 compound treatment 756910.0 145000.0 0.65 710046.0 148000.0 0.73 0.9777 0.9981 1670964 ChemDiv1_003817 COc1ccc(cc1CSc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N12 compound treatment 729276.0 117000.0 0.53 689106.0 127000.0 0.63 0.8168 0.9959 1161866 ChemDiv1_003818 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OCc4ccccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N13 compound treatment 765795.0 154000.0 0.69 715580.0 154000.0 0.76 1.0252 0.9988 1202218 ChemDiv1_003819 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N14 compound treatment 745972.0 134000.0 0.6 653621.0 91700.0 0.45 0.7454 0.9906 1367931 ChemDiv1_003820 Cc1cc2OC(=C(C#N)C(c3ccccc3OCc4ccccc4Cl)c2c(=O)o1)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N15 compound treatment 748867.0 137000.0 0.61 699402.0 137000.0 0.68 0.9149 0.9986 1342184 ChemDiv1_003821 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4Nc5ccccc5C(=O)N4Cc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N16 compound treatment 727406.0 115000.0 0.52 689037.0 127000.0 0.63 0.8107 0.9952 1972160 ChemDiv1_003822 COc1ccc(cc1COc2ccccc2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N17 compound treatment 729006.0 117000.0 0.52 721844.0 160000.0 0.79 0.9307 0.9799 1972161 ChemDiv1_003823 CCOC(=O)c1ccccc1OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N18 compound treatment 747584.0 136000.0 0.61 693305.0 131000.0 0.65 0.8895 0.9994 1972162 ChemDiv1_003824 COc1ccc(Br)cc1C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N19 compound treatment 816114.0 204000.0 0.91 722661.0 161000.0 0.8 1.2093 0.9976 1972163 ChemDiv1_003825 O=C1C2CCC3(CC2C(=O)N1Cc4ccccc4)OCCO3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N20 compound treatment 741141.0 129000.0 0.58 688501.0 127000.0 0.63 0.8523 0.9992 1282289 ChemDiv1_003826 CCCOc1ccc(cc1OC)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N21 compound treatment 740748.0 129000.0 0.58 701450.0 140000.0 0.69 0.8964 0.9959 1724806 ChemDiv1_003827 O=C1N(CCCc2nc3ccccc3c(=O)n2Cc4ccccc4)C(=O)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N22 compound treatment 727692.0 116000.0 0.52 627397.0 65500.0 0.32 0.5957 0.9745 1463713 ChemDiv1_003828 Clc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCCC5)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N23 mock treatment 709106.0 97200.0 0.43 656190.0 94200.0 0.47 0.6377 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 N24 mock treatment 515775.0 -96200.0 -0.43 402486.0 -159000.0 -0.79 -0.8629 -0.9592 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O01 compound treatment 654917.0 43000.0 0.19 564395.0 2450.0 0.01 0.1446 0.7502 1972164 ChemDiv1_003829 CC(=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O02 compound treatment 641513.0 29600.0 0.13 589935.0 28000.0 0.14 0.1917 0.9997 1972165 ChemDiv1_003830 CC(C)(C)c1ccc(Oc2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O03 compound treatment 678750.0 66800.0 0.3 619067.0 57100.0 0.28 0.4116 0.9996 1222174 ChemDiv1_003831 CCOC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O04 compound treatment 684389.0 72500.0 0.32 597909.0 36000.0 0.18 0.3553 0.9602 1947746 ChemDiv1_003832 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O05 compound treatment 722964.0 111000.0 0.5 626964.0 65000.0 0.32 0.5792 0.978 1156086 ChemDiv1_003833 CCCCC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O06 compound treatment 661958.0 50000.0 0.22 627319.0 65400.0 0.32 0.3873 0.9838 1267091 ChemDiv1_003834 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OC(C)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O07 compound treatment 724898.0 113000.0 0.51 652286.0 90300.0 0.45 0.674 0.9981 1972166 ChemDiv1_003835 CC(C)C(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(Br)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O08 compound treatment 697480.0 85500.0 0.38 630582.0 68600.0 0.34 0.5112 0.9982 1972167 ChemDiv1_003836 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O09 compound treatment 712058.0 100000.0 0.45 655901.0 94000.0 0.47 0.646 0.9998 1623516 ChemDiv1_003837 COc1ccc(cc1OC)C2N(C(=O)Cc3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O10 compound treatment 695484.0 83500.0 0.37 621508.0 59600.0 0.3 0.4731 0.9931 1972168 ChemDiv1_003838 COc1cc(OC)cc(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O11 compound treatment 703599.0 91700.0 0.41 665047.0 103000.0 0.51 0.6513 0.9941 1440060 ChemDiv1_003839 CCOc1cc(ccc1OC(=O)C)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O12 compound treatment 683250.0 71300.0 0.32 612041.0 50100.0 0.25 0.4012 0.9922 1425465 ChemDiv1_003840 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cccnc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O13 compound treatment 677707.0 65800.0 0.29 634547.0 72600.0 0.36 0.4625 0.9951 1783841 ChemDiv1_003841 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3NC2c4ccc(o4)c5ccc(cc5Cl)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O14 compound treatment 683008.0 71100.0 0.32 643031.0 81100.0 0.4 0.509 0.9933 1672961 ChemDiv1_003842 CCOc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O15 compound treatment 745770.0 134000.0 0.6 679133.0 117000.0 0.58 0.8341 0.9999 1512562 ChemDiv1_003843 CCOc1ccccc1C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O16 compound treatment 663843.0 51900.0 0.23 623234.0 61300.0 0.3 0.379 0.9913 1927506 ChemDiv1_003844 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O17 compound treatment 737352.0 125000.0 0.56 676979.0 115000.0 0.57 0.7999 1.0 1373677 ChemDiv1_003845 COc1cc(cc(OC)c1OC)C2N(C(=O)c3ccccc3)c4ccccc4NC5=C2C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O18 compound treatment 717592.0 106000.0 0.47 641684.0 79700.0 0.4 0.6138 0.996 1972169 ChemDiv1_003846 Cc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O19 compound treatment 751369.0 139000.0 0.62 658340.0 96400.0 0.48 0.779 0.9913 1948568 ChemDiv1_003847 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O20 compound treatment 705137.0 93200.0 0.42 619306.0 57400.0 0.28 0.4959 0.9825 1500574 ChemDiv1_003848 Cc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O21 compound treatment 724110.0 112000.0 0.5 650856.0 88900.0 0.44 0.6665 0.9979 1972170 ChemDiv1_003849 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3ccc(c4nc5ccccc5s4)c(O)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O22 compound treatment 716601.0 105000.0 0.47 603421.0 41500.0 0.21 0.4766 0.9316 1697087 ChemDiv1_003850 O=c1n(c2ccccc2)c(=S)[nH]c3sc4CCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O23 mock treatment 700982.0 89000.0 0.4 627690.0 65700.0 0.33 0.5122 0.995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 O24 mock treatment 149506.0 -462000.0 -2.07 415760.0 -146000.0 -0.72 -1.9758 -0.9009 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P01 compound treatment 617573.0 5640.0 0.03 549267.0 -12700.0 -0.06 -0.0266 -0.3924 1972171 ChemDiv1_003851 COc1ccc(/C=C(\C#N)/C(=O)Nn2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P02 compound treatment 644461.0 32500.0 0.15 562936.0 991.0 0.0 0.1064 0.7305 1707355 ChemDiv1_003852 CCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(cc4)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P03 compound treatment 650804.0 38900.0 0.17 578115.0 16200.0 0.08 0.1797 0.938 1467969 ChemDiv1_003853 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P04 compound treatment 650041.0 38100.0 0.17 618539.0 56600.0 0.28 0.3189 0.9716 1206674 ChemDiv1_003854 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cc(Cl)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P05 compound treatment 646257.0 34300.0 0.15 600521.0 38600.0 0.19 0.2438 0.9941 1118146 ChemDiv1_003855 COc1cc(cc(OC)c1OC)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P06 compound treatment 677978.0 66000.0 0.3 613513.0 51600.0 0.26 0.3897 0.9974 1924167 ChemDiv1_003856 COc1ccccc1c2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P07 compound treatment 705962.0 94000.0 0.42 582337.0 20400.0 0.1 0.3691 0.8526 1517667 ChemDiv1_003857 COc1ccc(cc1COc2ccc(F)cc2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P08 compound treatment 650632.0 38700.0 0.17 612873.0 50900.0 0.25 0.3009 0.9832 1972172 ChemDiv1_003858 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccccc2F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P09 compound treatment 663803.0 51900.0 0.23 623231.0 61300.0 0.3 0.3789 0.9912 1473601 ChemDiv1_003859 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(CSc5ccccn5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P10 compound treatment 708388.0 96500.0 0.43 603041.0 41100.0 0.2 0.4493 0.9411 1972173 ChemDiv1_003860 CCCCOc1ccc(cc1OC)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P11 compound treatment 687284.0 75300.0 0.34 620197.0 58300.0 0.29 0.4426 0.997 1612531 ChemDiv1_003861 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P12 compound treatment 701899.0 90000.0 0.4 630665.0 68700.0 0.34 0.5255 0.9965 1505633 ChemDiv1_003862 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OCc4ccc(Cl)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P13 compound treatment 716329.0 104000.0 0.47 633997.0 72100.0 0.36 0.5828 0.9912 1424987 ChemDiv1_003863 COc1ccc(cc1COc2ccccc2F)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P14 compound treatment 704956.0 93000.0 0.42 624465.0 62500.0 0.31 0.5134 0.9894 1972174 ChemDiv1_003864 COc1ccc(cc1COc2ccc(F)cc2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P15 compound treatment 700467.0 88500.0 0.4 614834.0 52900.0 0.26 0.4655 0.9798 1434459 ChemDiv1_003865 COc1ccc(cc1CSc2nc3ccccc3s2)C4Nc5ccccc5C(=O)N4Cc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P16 compound treatment 713997.0 102000.0 0.46 627588.0 65600.0 0.33 0.553 0.9861 1972175 ChemDiv1_003866 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(o3)c4cc(ccc4Cl)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P17 compound treatment 698732.0 86800.0 0.39 624590.0 62600.0 0.31 0.4942 0.9938 1348575 ChemDiv1_003867 COc1cccc(OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3c5cccc6ccccc56)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P18 compound treatment 681065.0 69100.0 0.31 639421.0 77500.0 0.38 0.4902 0.9943 1972176 ChemDiv1_003868 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(cc2)C(F)(F)F)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P19 compound treatment 697727.0 85800.0 0.38 635630.0 73700.0 0.37 0.5297 0.9997 1366774 ChemDiv1_003869 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P20 compound treatment 699057.0 87100.0 0.39 611518.0 49600.0 0.25 0.4494 0.9751 1398782 ChemDiv1_003870 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCc4ccccc4)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P21 compound treatment 705657.0 93700.0 0.42 598796.0 36900.0 0.18 0.4257 0.9305 1263674 ChemDiv1_003871 O=C1N(CCCc2nc3ccccc3c(=O)n2CCCn4ccnc4)C(=O)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P22 compound treatment 685278.0 73300.0 0.33 613524.0 51600.0 0.26 0.4128 0.9923 1784338 ChemDiv1_003872 [O-][N+](=O)c1cccc(c1)C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P23 mock treatment 683932.0 72000.0 0.32 580127.0 18200.0 0.09 0.2916 0.8713 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.597 P24 mock treatment 224086.0 -388000.0 -1.74 222107.0 -340000.0 -1.68 -2.4181 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A01 compound treatment 565463.0 -3980.0 -0.02 530197.0 -20200.0 -0.1 -0.0835 -0.8199 1463327 ChemDiv1_003873 CC(NC(=O)c1ccc2OCCOc2c1)C3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A02 compound treatment 561484.0 -7960.0 -0.04 510462.0 -40000.0 -0.2 -0.1652 -0.8211 1723746 ChemDiv1_003874 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OCc5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A03 compound treatment 584361.0 14900.0 0.07 532612.0 -17800.0 -0.09 -0.0152 -0.1372 1563473 ChemDiv1_003875 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A04 compound treatment 557304.0 -12100.0 -0.05 523520.0 -26900.0 -0.13 -0.1327 -0.9217 1949072 ChemDiv1_003876 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(F)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A05 compound treatment 582727.0 13300.0 0.06 552384.0 1950.0 0.01 0.0489 0.8116 1972177 ChemDiv1_003877 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A06 compound treatment 607743.0 38300.0 0.17 559579.0 9150.0 0.05 0.1533 0.8644 1972178 ChemDiv1_003878 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A07 compound treatment 611735.0 42300.0 0.19 564930.0 14500.0 0.07 0.1847 0.912 1972179 ChemDiv1_003879 CC(C)(C)c1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A08 compound treatment 631396.0 62000.0 0.28 585042.0 34600.0 0.17 0.3173 0.9733 1924438 ChemDiv1_003880 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A09 compound treatment 610921.0 41500.0 0.19 610883.0 60500.0 0.3 0.3431 0.9736 1972180 ChemDiv1_003881 Brc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A10 compound treatment 858739.0 289000.0 1.3 918107.0 368000.0 1.82 2.2036 0.986 1729280 ChemDiv1_003882 CC(=O)Nc1ccc(cc1)c2nc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A11 compound treatment 625631.0 56200.0 0.25 617408.0 67000.0 0.33 0.4125 0.9907 1438346 ChemDiv1_003883 CCOc1cc(ccc1OC(=O)C2CC2)C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc(OC)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A12 compound treatment 741739.0 172000.0 0.77 788972.0 239000.0 1.18 1.381 0.9786 1331516 ChemDiv1_003884 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A13 compound treatment 593704.0 24300.0 0.11 622880.0 72500.0 0.36 0.3306 0.8816 1339658 ChemDiv1_003885 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(Br)s5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A14 compound treatment 689386.0 120000.0 0.54 660453.0 110000.0 0.55 0.7651 1.0 1972181 ChemDiv1_003886 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3Br)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A15 compound treatment 643095.0 73700.0 0.33 599179.0 48700.0 0.24 0.4039 0.9883 1924588 ChemDiv1_003887 Brc1cc2OCOc2cc1C3Nc4ccccc4NC5=C3C(=O)CC(C5)c6ccc7OCOc7c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A16 compound treatment 639557.0 70100.0 0.31 629887.0 79500.0 0.39 0.5003 0.9937 1471125 ChemDiv1_003888 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccccc3C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A17 compound treatment 657138.0 87700.0 0.39 610481.0 60100.0 0.3 0.4879 0.9906 1929185 ChemDiv1_003889 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc(Cl)c1OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A18 compound treatment 642624.0 73200.0 0.33 607962.0 57500.0 0.29 0.4332 0.9976 1163079 ChemDiv1_003890 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccccc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A19 compound treatment 610396.0 41000.0 0.18 611576.0 61100.0 0.3 0.3438 0.9711 1972182 ChemDiv1_003891 CCOC(=O)COc1ccc(Br)cc1C=C2C(=O)NC(=O)NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A20 compound treatment 590803.0 21400.0 0.1 596604.0 46200.0 0.23 0.2294 0.9251 1972183 ChemDiv1_003892 COc1ccc(Br)c(c1)C(=O)On2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A21 compound treatment 634860.0 65400.0 0.29 601881.0 51500.0 0.25 0.3873 0.9976 1972184 ChemDiv1_003893 COc1cc(ccc1OCC(=O)Nc2ccc3OCOc3c2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A22 compound treatment 603353.0 33900.0 0.15 587675.0 37200.0 0.18 0.2378 0.9953 1972185 ChemDiv1_003894 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A23 mock treatment 565029.0 -4410.0 -0.02 559061.0 8630.0 0.04 0.0163 0.3454 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 A24 mock treatment 161471.0 -408000.0 -1.83 497166.0 -53300.0 -0.26 -1.4779 -0.801 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B01 compound treatment 595180.0 25700.0 0.12 526321.0 -24100.0 -0.12 -0.003 -0.018 1972186 ChemDiv1_003895 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B02 compound treatment 646673.0 77200.0 0.35 555427.0 5000.0 0.02 0.262 0.7558 1925285 ChemDiv1_003896 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6cccs6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B03 compound treatment 678508.0 109000.0 0.49 594300.0 43900.0 0.22 0.4989 0.9336 1929108 ChemDiv1_003897 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B04 compound treatment 643374.0 73900.0 0.33 591944.0 41500.0 0.21 0.3794 0.9738 1972187 ChemDiv1_003898 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B05 compound treatment 695630.0 126000.0 0.56 631594.0 81200.0 0.4 0.6837 0.9861 1929184 ChemDiv1_003899 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccc(C)cc3)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B06 compound treatment 678626.0 109000.0 0.49 627670.0 77200.0 0.38 0.6162 0.9927 1972188 ChemDiv1_003900 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)Nc3sc4CCCCc4c3C#N)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B07 compound treatment 1089726.0 520000.0 2.33 1106446.0 556000.0 2.75 3.5945 0.9965 1948721 ChemDiv1_003901 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B08 compound treatment 734360.0 165000.0 0.74 675651.0 125000.0 0.62 0.9606 0.9963 1925250 ChemDiv1_003902 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B09 compound treatment 719546.0 150000.0 0.67 710794.0 160000.0 0.79 1.0369 0.9965 1379236 ChemDiv1_003903 CC1CCCN(CN2C(=O)C3(OCCO3)c4ccccc24)C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B10 compound treatment 718736.0 149000.0 0.67 702456.0 152000.0 0.75 1.0051 0.9982 1972189 ChemDiv1_003904 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B11 compound treatment 701981.0 133000.0 0.59 710930.0 161000.0 0.8 0.9817 0.9896 1972190 ChemDiv1_003905 Fc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B12 compound treatment 707961.0 139000.0 0.62 697107.0 147000.0 0.73 0.9522 0.9969 1972191 ChemDiv1_003906 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B13 compound treatment 719283.0 150000.0 0.67 717491.0 167000.0 0.83 1.0595 0.9946 1972192 ChemDiv1_003907 CC1CCc2c(C(=O)N)c(NC(=O)c3cc4nc(cc(n4n3)C(F)(F)F)c5ccco5)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B14 compound treatment 735710.0 166000.0 0.74 698970.0 149000.0 0.74 1.0466 1.0 1972193 ChemDiv1_003908 Cc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(CC4)C(=O)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B15 compound treatment 753340.0 184000.0 0.82 729177.0 179000.0 0.89 1.2082 0.9993 1972194 ChemDiv1_003909 Cc1ccc(cc1)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B16 compound treatment 725929.0 156000.0 0.7 700911.0 150000.0 0.75 1.0224 0.9995 1930326 ChemDiv1_003910 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCc4cccs4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B17 compound treatment 767232.0 198000.0 0.89 749967.0 200000.0 0.99 1.325 0.9985 1972195 ChemDiv1_003911 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3ccc(Cl)cc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B18 compound treatment 710778.0 141000.0 0.63 710082.0 160000.0 0.79 1.0066 0.9939 1972196 ChemDiv1_003912 Cc1ccc(cc1)C2CC(n3ncc(C(=O)Nc4cc(Sc5ccc(Br)cc5)cc(c4)[N+](=O)[O-])c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B19 compound treatment 718511.0 149000.0 0.67 715368.0 165000.0 0.82 1.0496 0.9949 1924548 ChemDiv1_003913 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c(OC)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B20 compound treatment 695565.0 126000.0 0.56 661409.0 111000.0 0.55 0.788 0.9999 1972197 ChemDiv1_003914 O=C(N1CCOCC1)c2ccc(NS(=O)(=O)c3ccc4C(=O)c5ccccc5C(=O)c4c3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B21 compound treatment 721833.0 152000.0 0.68 688491.0 138000.0 0.68 0.966 1.0 1930258 ChemDiv1_003915 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B22 compound treatment 747133.0 178000.0 0.8 713158.0 163000.0 0.81 1.1325 1.0 1446667 ChemDiv1_003916 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B23 mock treatment 664451.0 95000.0 0.43 635036.0 84600.0 0.42 0.5971 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 B24 mock treatment 497051.0 -72400.0 -0.32 487556.0 -62900.0 -0.31 -0.4494 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C01 compound treatment 600671.0 31200.0 0.14 523651.0 -26800.0 -0.13 0.005 0.0262 1175574 ChemDiv1_003917 CCOc1cccc(c1)C(=O)Nc2cc(ccc2Cl)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C02 compound treatment 798069.0 229000.0 1.02 611328.0 60900.0 0.3 0.937 0.8782 1611526 ChemDiv1_003918 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C03 compound treatment 672103.0 103000.0 0.46 583930.0 33500.0 0.17 0.4423 0.9052 1222832 ChemDiv1_003919 O=C(CSc1nc2ccccc2s1)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C04 compound treatment 641526.0 72100.0 0.32 585518.0 35100.0 0.17 0.3511 0.9579 1924433 ChemDiv1_003920 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C05 compound treatment 664538.0 95100.0 0.43 634251.0 83800.0 0.42 0.5946 0.9999 1972198 ChemDiv1_003921 CCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C06 compound treatment 664059.0 94600.0 0.42 611785.0 61400.0 0.3 0.5144 0.9868 1972199 ChemDiv1_003922 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C07 compound treatment 676666.0 107000.0 0.48 643842.0 93400.0 0.46 0.6666 0.9998 1972200 ChemDiv1_003923 Clc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C08 compound treatment 656156.0 86700.0 0.39 668115.0 118000.0 0.58 0.6867 0.9805 1924587 ChemDiv1_003924 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C09 compound treatment 712689.0 143000.0 0.64 689500.0 139000.0 0.69 0.9406 0.9994 1972201 ChemDiv1_003925 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(C)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C10 compound treatment 691446.0 122000.0 0.55 673294.0 123000.0 0.61 0.8166 0.9985 1156448 ChemDiv1_003926 CC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C11 compound treatment 711045.0 142000.0 0.63 703758.0 153000.0 0.76 0.9853 0.996 1284246 ChemDiv1_003927 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C12 compound treatment 683845.0 114000.0 0.51 697863.0 147000.0 0.73 0.8786 0.9849 1972202 ChemDiv1_003928 COc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Cl)c1OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C13 compound treatment 719782.0 150000.0 0.67 705183.0 155000.0 0.77 1.018 0.9979 1674807 ChemDiv1_003929 CCOc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C14 compound treatment 712263.0 143000.0 0.64 690804.0 140000.0 0.7 0.9438 0.9991 1972203 ChemDiv1_003930 COc1cc(Br)c(cc1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C15 compound treatment 743236.0 174000.0 0.78 749071.0 199000.0 0.98 1.2459 0.9932 1972204 ChemDiv1_003931 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C16 compound treatment 705312.0 136000.0 0.61 719621.0 169000.0 0.84 1.0227 0.9876 1145640 ChemDiv1_003932 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C17 compound treatment 727626.0 158000.0 0.71 713074.0 163000.0 0.81 1.0704 0.9979 1947191 ChemDiv1_003933 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(Cl)c(c3)C(=O)O)c4cccc(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C18 compound treatment 702222.0 133000.0 0.59 683027.0 133000.0 0.66 0.8848 0.9988 1948720 ChemDiv1_003934 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C19 compound treatment 1674725.0 1110000.0 4.95 1823491.0 1270000.0 6.31 7.9579 0.9928 1972205 ChemDiv1_003935 COc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Br)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C20 compound treatment 697471.0 128000.0 0.57 655918.0 105000.0 0.52 0.7748 0.9989 1972206 ChemDiv1_003936 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(c(Br)c4C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C21 compound treatment 705482.0 136000.0 0.61 681397.0 131000.0 0.65 0.8894 0.9995 1229431 ChemDiv1_003937 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C22 compound treatment 672965.0 104000.0 0.46 664328.0 114000.0 0.56 0.7267 0.9952 1972207 ChemDiv1_003938 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(c(Br)c4C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C23 mock treatment 661155.0 91700.0 0.41 648124.0 97700.0 0.48 0.6325 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 C24 mock treatment 139654.0 -430000.0 -1.92 271981.0 -278000.0 -1.38 -2.3358 -0.9867 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D01 compound treatment 649227.0 79800.0 0.36 535075.0 -15400.0 -0.08 0.1988 0.5443 1927707 ChemDiv1_003939 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCSc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D02 compound treatment 641953.0 72500.0 0.32 563798.0 13400.0 0.07 0.2763 0.8342 1972208 ChemDiv1_003940 CCOc1ccc(Oc2cc(NC(=O)c3cnn4C(CC(Nc34)c5cccs5)C(F)(F)F)cc(c2)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D03 compound treatment 683850.0 114000.0 0.51 593149.0 42700.0 0.21 0.5118 0.9236 1972209 ChemDiv1_003941 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3cccc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D04 compound treatment 690325.0 121000.0 0.54 590585.0 40200.0 0.2 0.5233 0.9077 1924328 ChemDiv1_003942 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)N4CCN(Cc5ccccc5)CC4)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D05 compound treatment 676419.0 107000.0 0.48 637844.0 87400.0 0.43 0.6448 0.9987 1949044 ChemDiv1_003943 CC(C)(C)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D06 compound treatment 665285.0 95800.0 0.43 608997.0 58600.0 0.29 0.5085 0.9819 1924440 ChemDiv1_003944 CCOC(=O)c1sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc5OCOc5c4)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D07 compound treatment 724805.0 155000.0 0.7 699209.0 149000.0 0.74 1.0129 0.9996 1925375 ChemDiv1_003945 CCOC(=O)CSCCOc1ccc(C=C2C(=O)NC(=S)NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D08 compound treatment 734954.0 166000.0 0.74 676946.0 127000.0 0.63 0.9671 0.9965 1924351 ChemDiv1_003946 COc1ccccc1N2CCN(CC2)C(=O)c3cnn4C(CC(Nc34)c5ccc(Br)cc5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D09 compound treatment 722396.0 153000.0 0.68 723311.0 173000.0 0.86 1.0897 0.9938 1489354 ChemDiv1_003947 Cc1ccc(cc1Cl)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D10 compound treatment 763923.0 194000.0 0.87 760735.0 210000.0 1.04 1.3523 0.996 1972210 ChemDiv1_003948 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3sc4CCCCc4c3C#N)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D11 compound treatment 730258.0 161000.0 0.72 740539.0 190000.0 0.94 1.175 0.9912 1709596 ChemDiv1_003949 COc1cccc(c1)C(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D12 compound treatment 731521.0 162000.0 0.73 714208.0 164000.0 0.81 1.0867 0.9984 1972211 ChemDiv1_003950 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccco4)C(F)(F)F)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D13 compound treatment 765303.0 196000.0 0.88 765401.0 215000.0 1.06 1.373 0.9953 1972212 ChemDiv1_003951 CC(C)OC(=O)c1c(NC(=O)Cn2nc([N+](=O)[O-])c(Br)c2C)sc3CC(C)CCc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D14 compound treatment 761582.0 192000.0 0.86 750229.0 200000.0 0.99 1.308 0.9976 1972213 ChemDiv1_003952 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc(cc4)C(C)O)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D15 compound treatment 768124.0 199000.0 0.89 770086.0 220000.0 1.09 1.3983 0.995 1972214 ChemDiv1_003953 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D16 compound treatment 759766.0 190000.0 0.85 757825.0 207000.0 1.03 1.3289 0.9957 1930322 ChemDiv1_003954 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc5OCOc5c4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D17 compound treatment 769914.0 200000.0 0.9 775422.0 225000.0 1.11 1.4227 0.9942 1972215 ChemDiv1_003955 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3cccc(Cl)c3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D18 compound treatment 749170.0 180000.0 0.8 754831.0 204000.0 1.01 1.2849 0.9935 1972216 ChemDiv1_003956 Cc1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(C)cc4)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D19 compound treatment 776120.0 207000.0 0.93 767617.0 217000.0 1.08 1.415 0.9972 1930345 ChemDiv1_003957 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D20 compound treatment 708633.0 139000.0 0.62 711638.0 161000.0 0.8 1.0053 0.9925 1621854 ChemDiv1_003958 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D21 compound treatment 764878.0 195000.0 0.87 735772.0 185000.0 0.92 1.2678 0.9997 1924463 ChemDiv1_003959 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3nn4C(CC(Nc4c3Cl)c5cccs5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D22 compound treatment 848155.0 279000.0 1.25 787169.0 237000.0 1.17 1.7115 0.9995 1602163 ChemDiv1_003960 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3OC(=O)C)c(=O)n2C1c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D23 mock treatment 701471.0 132000.0 0.59 679611.0 129000.0 0.64 0.8704 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 D24 mock treatment 494486.0 -75000.0 -0.34 485672.0 -64800.0 -0.32 -0.4641 -0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E01 compound treatment 624347.0 54900.0 0.25 537808.0 -12600.0 -0.06 0.1296 0.511 1277264 ChemDiv1_003961 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(c3nc4ccccc4s3)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E02 compound treatment 634001.0 64600.0 0.29 552415.0 1990.0 0.01 0.2113 0.7308 1385254 ChemDiv1_003962 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(Br)c4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E03 compound treatment 685629.0 116000.0 0.52 620784.0 70400.0 0.35 0.6142 0.981 1494085 ChemDiv1_003963 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E04 compound treatment 649411.0 80000.0 0.36 596707.0 46300.0 0.23 0.4152 0.9768 1924459 ChemDiv1_003964 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2F)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E05 compound treatment 690058.0 121000.0 0.54 629509.0 79100.0 0.39 0.6588 0.9876 1972217 ChemDiv1_003965 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E06 compound treatment 691595.0 122000.0 0.55 644569.0 94100.0 0.47 0.7164 0.9969 1925598 ChemDiv1_003966 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2cccs2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E07 compound treatment 724593.0 155000.0 0.69 724561.0 174000.0 0.86 1.1011 0.9942 1607679 ChemDiv1_003967 CCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E08 compound treatment 710794.0 141000.0 0.63 693150.0 143000.0 0.71 0.9474 0.9985 1972218 ChemDiv1_003968 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E09 compound treatment 713533.0 144000.0 0.65 700773.0 150000.0 0.74 0.9827 0.9974 1972219 ChemDiv1_003969 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Cl)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E10 compound treatment 692479.0 123000.0 0.55 715368.0 165000.0 0.82 0.9672 0.9816 1230466 ChemDiv1_003970 CC(=O)Nc1cccc(c1)c2nc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E11 compound treatment 707271.0 138000.0 0.62 752236.0 202000.0 1.0 1.1432 0.9731 1216946 ChemDiv1_003971 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E12 compound treatment 705791.0 136000.0 0.61 710333.0 160000.0 0.79 0.9917 0.9917 1496354 ChemDiv1_003972 CC1CCN(CC1)c2nc(NCc3cccnc3)nc(n2)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E13 compound treatment 672782.0 103000.0 0.46 770935.0 221000.0 1.09 1.0995 0.9269 1297290 ChemDiv1_003973 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(C)cc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E14 compound treatment 745932.0 176000.0 0.79 760520.0 210000.0 1.04 1.2946 0.9908 1165062 ChemDiv1_003974 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E15 compound treatment 782864.0 213000.0 0.96 801711.0 251000.0 1.24 1.5557 0.9915 1674241 ChemDiv1_003975 CCOc1ccccc1C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E16 compound treatment 731315.0 162000.0 0.72 736688.0 186000.0 0.92 1.1648 0.9928 1924592 ChemDiv1_003976 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccs2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E17 compound treatment 759292.0 190000.0 0.85 757713.0 207000.0 1.03 1.327 0.9956 1972220 ChemDiv1_003977 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E18 compound treatment 763504.0 194000.0 0.87 776814.0 226000.0 1.12 1.4073 0.992 1606919 ChemDiv1_003978 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4cc(C)c(C)cc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E19 compound treatment 755854.0 186000.0 0.83 787819.0 237000.0 1.18 1.4216 0.9859 1972221 ChemDiv1_003979 OC(=O)c1cccc(c1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E20 compound treatment 720013.0 151000.0 0.67 683139.0 133000.0 0.66 0.9415 0.9999 1972222 ChemDiv1_003980 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E21 compound treatment 901801.0 332000.0 1.49 976281.0 426000.0 2.11 2.5437 0.9854 1972223 ChemDiv1_003981 COc1cc(/C=C/2\Sc3ccccc3C2=O)c(Br)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E22 compound treatment 683013.0 114000.0 0.51 688692.0 138000.0 0.68 0.8438 0.9892 1972224 ChemDiv1_003982 OC(=O)c1n[nH]c(NC(=O)c2ccc(Br)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E23 mock treatment 668184.0 98700.0 0.44 692573.0 142000.0 0.7 0.8105 0.9748 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 E24 mock treatment 324001.0 -245000.0 -1.1 191402.0 -359000.0 -1.78 -2.0345 -0.9732 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F01 compound treatment 628713.0 59300.0 0.27 578142.0 27700.0 0.14 0.2847 0.953 1927496 ChemDiv1_003983 CC(C)(C)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F02 compound treatment 652975.0 83500.0 0.37 561243.0 10800.0 0.05 0.3023 0.8002 1972225 ChemDiv1_003984 [O-][N+](=O)c1cc(NC(=O)c2cnn3C(CC(Nc23)c4ccco4)C(F)(F)F)cc(Oc5ccc6CCCc6c5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F03 compound treatment 673868.0 104000.0 0.47 598689.0 48300.0 0.24 0.4996 0.9515 1972226 ChemDiv1_003985 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F04 compound treatment 684156.0 115000.0 0.51 592424.0 42000.0 0.21 0.5102 0.9209 1925366 ChemDiv1_003986 COc1cc(NC(=O)c2cnn3C(CC(Nc23)c4cc(OC)c(OC)c(OC)c4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F05 compound treatment 720002.0 151000.0 0.67 655829.0 105000.0 0.52 0.8458 0.992 1948826 ChemDiv1_003987 Cc1ccc(OCCOc2ccc(Cl)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F06 compound treatment 698531.0 129000.0 0.58 634639.0 84200.0 0.42 0.7036 0.9872 1925361 ChemDiv1_003988 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Br)cc4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F07 compound treatment 746884.0 177000.0 0.79 675070.0 125000.0 0.62 0.9983 0.9922 1926156 ChemDiv1_003989 CCOC(=O)CSCCOc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F08 compound treatment 745770.0 176000.0 0.79 685838.0 135000.0 0.67 1.0324 0.9967 1925386 ChemDiv1_003990 COc1cc(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F09 compound treatment 723615.0 154000.0 0.69 709185.0 159000.0 0.79 1.0441 0.9979 1368321 ChemDiv1_003991 O=C1N(CN2CCOCC2)c3ccccc3C41OCCCO4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F10 compound treatment 677426.0 108000.0 0.48 705306.0 155000.0 0.77 0.8843 0.9752 1972227 ChemDiv1_003992 CCOC(=O)c1c(NC(=O)c2nn3C(CC(Nc3c2Br)c4ccco4)C(F)(F)F)sc5CCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F11 compound treatment 664933.0 95500.0 0.43 741659.0 191000.0 0.95 0.9721 0.9354 1972228 ChemDiv1_003993 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F12 compound treatment 708606.0 139000.0 0.62 746700.0 196000.0 0.97 1.128 0.9769 1925345 ChemDiv1_003994 COc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F13 compound treatment 766355.0 197000.0 0.88 743065.0 193000.0 0.95 1.2981 0.9992 1972229 ChemDiv1_003995 COc1cc(cc(OC)c1OC)c2cc(n3ncc(C(=O)NC4CCCCC4)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F14 compound treatment 753864.0 184000.0 0.83 776958.0 227000.0 1.12 1.3772 0.9886 1929817 ChemDiv1_003996 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F15 compound treatment 808170.0 239000.0 1.07 832572.0 282000.0 1.4 1.744 0.9912 1972230 ChemDiv1_003997 FC(F)(F)c1c2CCc3ccccc3-c2nc4c(Cl)c(nn14)C(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F16 compound treatment 770283.0 201000.0 0.9 736654.0 186000.0 0.92 1.288 0.9999 1972231 ChemDiv1_003998 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(OC)c(OC)c4)C(F)(F)F)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F17 compound treatment 790381.0 221000.0 0.99 788688.0 238000.0 1.18 1.5339 0.9961 1931589 ChemDiv1_003999 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCCN3CCOCC3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F18 compound treatment 739443.0 170000.0 0.76 711097.0 161000.0 0.8 1.1009 0.9997 1972232 ChemDiv1_004000 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F19 compound treatment 844110.0 275000.0 1.23 826900.0 276000.0 1.37 1.8378 0.9986 1972233 ChemDiv1_004001 COc1ccc(CNC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F20 compound treatment 1412215.0 843000.0 3.77 1209688.0 659000.0 3.27 4.9769 0.9974 1469829 ChemDiv1_004002 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F21 compound treatment 762033.0 193000.0 0.86 741432.0 191000.0 0.95 1.2787 0.9989 1972234 ChemDiv1_004003 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F22 compound treatment 726891.0 157000.0 0.7 720588.0 170000.0 0.84 1.0944 0.996 1520971 ChemDiv1_004004 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F23 mock treatment 708841.0 139000.0 0.62 691655.0 141000.0 0.7 0.9359 0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 F24 mock treatment 540343.0 -29100.0 -0.13 489084.0 -61300.0 -0.3 -0.307 -0.9285 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G01 compound treatment 612963.0 43500.0 0.19 522391.0 -28000.0 -0.14 0.0395 0.1653 1943454 ChemDiv1_004005 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G02 compound treatment 634865.0 65400.0 0.29 554894.0 4460.0 0.02 0.2227 0.7584 1934980 ChemDiv1_004006 Cc1cc(C)n(n1)c2nc3nonc3nc2Nc4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G03 compound treatment 682655.0 113000.0 0.51 597887.0 47500.0 0.24 0.5246 0.939 1946967 ChemDiv1_004007 CCOC(=O)CSc1nc2ccc(N)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G04 compound treatment 664882.0 95400.0 0.43 586247.0 35800.0 0.18 0.4276 0.9242 1924638 ChemDiv1_004008 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(F)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G05 compound treatment 657062.0 87600.0 0.39 596457.0 46000.0 0.23 0.4386 0.9667 1972235 ChemDiv1_004009 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G06 compound treatment 618532.0 49100.0 0.22 638989.0 88600.0 0.44 0.4656 0.9489 1972236 ChemDiv1_004010 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(C)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G07 compound treatment 732004.0 163000.0 0.73 720265.0 170000.0 0.84 1.1095 0.9974 1972237 ChemDiv1_004011 CCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G08 compound treatment 696538.0 127000.0 0.57 649778.0 99300.0 0.49 0.7503 0.9974 1972238 ChemDiv1_004012 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G09 compound treatment 704612.0 135000.0 0.61 706991.0 157000.0 0.78 0.9763 0.9925 1972239 ChemDiv1_004013 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Br)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G10 compound treatment 678183.0 109000.0 0.49 680129.0 130000.0 0.64 0.7985 0.9906 1972240 ChemDiv1_004014 O=C(Nc1nc2ccc3ccccc3c2o1)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G11 compound treatment 706763.0 137000.0 0.61 720475.0 170000.0 0.84 1.0303 0.988 1147755 ChemDiv1_004015 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G12 compound treatment 716329.0 147000.0 0.66 743609.0 193000.0 0.96 1.1416 0.9832 1692006 ChemDiv1_004016 COc1nc(NCc2ccccc2)nc(NCc3cccnc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G13 compound treatment 689273.0 120000.0 0.54 738385.0 188000.0 0.93 1.0377 0.9657 1972241 ChemDiv1_004017 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G14 compound treatment 725841.0 156000.0 0.7 749746.0 199000.0 0.99 1.1932 0.9858 1302123 ChemDiv1_004018 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G15 compound treatment 761589.0 192000.0 0.86 786194.0 236000.0 1.17 1.4341 0.9887 1445573 ChemDiv1_004019 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(Cl)cc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G16 compound treatment 718415.0 149000.0 0.67 746647.0 196000.0 0.97 1.1589 0.9831 1182604 ChemDiv1_004020 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(SC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G17 compound treatment 763649.0 194000.0 0.87 761047.0 211000.0 1.04 1.3525 0.9959 1972242 ChemDiv1_004021 CCCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G18 compound treatment 694034.0 125000.0 0.56 725699.0 175000.0 0.87 1.0083 0.9771 1972243 ChemDiv1_004022 [O-][N+](=O)c1ccccc1C(=O)On2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G19 compound treatment 883121.0 314000.0 1.4 850954.0 301000.0 1.49 2.0456 0.9996 1972244 ChemDiv1_004023 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc4C(=O)NC(=O)c4c3)c5cccc(c5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G20 compound treatment 989773.0 420000.0 1.88 928416.0 378000.0 1.87 2.6545 1.0 1972245 ChemDiv1_004024 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G21 compound treatment 709947.0 141000.0 0.63 735436.0 185000.0 0.92 1.0928 0.9831 1972246 ChemDiv1_004025 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1Oc3ccc(cc3C#N)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G22 compound treatment 645578.0 76100.0 0.34 702150.0 152000.0 0.75 0.7725 0.936 1229623 ChemDiv1_004026 COc1cc(cc(OC)c1OC)C(=O)Nc2nnc(CC(=O)NCc3ccccc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G23 mock treatment 677616.0 108000.0 0.48 683017.0 133000.0 0.66 0.8068 0.9888 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 G24 mock treatment 272808.0 -297000.0 -1.33 260957.0 -289000.0 -1.43 -1.9529 -0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H01 compound treatment 625704.0 56300.0 0.25 552672.0 2240.0 0.01 0.1859 0.7376 1949048 ChemDiv1_004027 CC(C)(C)c1ccc(OCCOc2ccc(C=C3C(=O)NC(=S)NC3=O)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H02 compound treatment 659122.0 89700.0 0.4 561337.0 10900.0 0.05 0.3221 0.7951 1972247 ChemDiv1_004028 CCOC(=O)c1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccccc4)sc5CCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H03 compound treatment 685035.0 116000.0 0.52 599939.0 49500.0 0.25 0.5393 0.9418 1972248 ChemDiv1_004029 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H04 compound treatment 677140.0 108000.0 0.48 603512.0 53100.0 0.26 0.5268 0.9594 1972249 ChemDiv1_004030 COc1cc(cc(OC)c1OC)C2CC(n3ncc(C(=O)Nc4cc(Oc5ccc(F)cc5)cc(c4)[N+](=O)[O-])c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H05 compound treatment 696660.0 127000.0 0.57 655450.0 105000.0 0.52 0.7706 0.999 1948839 ChemDiv1_004031 Cc1ccc(OCCOc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H06 compound treatment 674164.0 105000.0 0.47 617183.0 66800.0 0.33 0.5653 0.9854 1929838 ChemDiv1_004032 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Br)cc4)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H07 compound treatment 715825.0 146000.0 0.66 690146.0 140000.0 0.69 0.9528 0.9996 1972250 ChemDiv1_004033 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(OC)cc3)ccc1OCCBr 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H08 compound treatment 712653.0 143000.0 0.64 691417.0 141000.0 0.7 0.9472 0.9991 1972251 ChemDiv1_004034 CC(C)OC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)sc5CCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H09 compound treatment 716138.0 147000.0 0.66 735312.0 185000.0 0.92 1.112 0.9867 1346450 ChemDiv1_004035 OC1(C2CCc3ccccc3C2=O)C(=O)Nc4ccc(Br)cc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H10 compound treatment 754784.0 185000.0 0.83 716266.0 166000.0 0.82 1.1676 1.0 1972252 ChemDiv1_004036 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H11 compound treatment 724370.0 155000.0 0.69 739947.0 190000.0 0.94 1.1542 0.9889 1972253 ChemDiv1_004037 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Br)c4ccccc4)C(F)(F)F)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H12 compound treatment 682288.0 113000.0 0.51 703394.0 153000.0 0.76 0.893 0.9806 1925357 ChemDiv1_004038 COc1ccc(cc1)C2CC(n3nc(C(=O)Nc4c(C)n(C)n(c5ccccc5)c4=O)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H13 compound treatment 721046.0 152000.0 0.68 775776.0 225000.0 1.12 1.2692 0.9715 1972254 ChemDiv1_004039 Cc1nn2c(cc(nc2c1C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccc(Cl)cc5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H14 compound treatment 715077.0 146000.0 0.65 750066.0 200000.0 0.99 1.1603 0.9795 1972255 ChemDiv1_004040 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4cccnc4Cl)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H15 compound treatment 759789.0 190000.0 0.85 780584.0 230000.0 1.14 1.4087 0.9897 1925262 ChemDiv1_004041 CCOC(=O)c1sc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H16 compound treatment 835210.0 266000.0 1.19 852238.0 302000.0 1.5 1.8984 0.9936 1972256 ChemDiv1_004042 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4cccc(c4)C(C)O)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H17 compound treatment 769938.0 200000.0 0.9 773469.0 223000.0 1.1 1.4159 0.9947 1972257 ChemDiv1_004043 Cc1ccc(O)c(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H18 compound treatment 742676.0 173000.0 0.78 722271.0 172000.0 0.85 1.1503 0.9989 1930361 ChemDiv1_004044 COc1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Cl)cc4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H19 compound treatment 802298.0 233000.0 1.04 780888.0 230000.0 1.14 1.5443 0.999 1929903 ChemDiv1_004045 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)Nc3ccc4OCOc4c3)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H20 compound treatment 795490.0 226000.0 1.01 776327.0 226000.0 1.12 1.5068 0.9987 1442665 ChemDiv1_004046 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H21 compound treatment 788057.0 219000.0 0.98 806044.0 256000.0 1.27 1.5874 0.9919 1929948 ChemDiv1_004047 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4cccs4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H22 compound treatment 746514.0 177000.0 0.79 754831.0 204000.0 1.01 1.2765 0.9927 1296152 ChemDiv1_004048 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(C)cc3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H23 mock treatment 695128.0 126000.0 0.56 653572.0 103000.0 0.51 0.7591 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 H24 mock treatment 520197.0 -49200.0 -0.22 186660.0 -364000.0 -1.8 -1.4301 -0.7877 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I01 compound treatment 616106.0 46700.0 0.21 517927.0 -32500.0 -0.16 0.0339 0.1284 1226264 ChemDiv1_004049 COc1ccc(cc1OC)C(=O)Nc2cc(ccc2C)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I02 compound treatment 649586.0 80100.0 0.36 541605.0 -8820.0 -0.04 0.2228 0.6164 1500171 ChemDiv1_004050 CCOC(=O)c1ccc(Nc2nc3nonc3nc2NC(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I03 compound treatment 678326.0 109000.0 0.49 585560.0 35100.0 0.17 0.4677 0.9037 1972258 ChemDiv1_004051 Nc1ccc2nc(SCC(=O)c3ccc(Br)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I04 compound treatment 674688.0 105000.0 0.47 584004.0 33600.0 0.17 0.4507 0.9022 1924497 ChemDiv1_004052 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccco2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I05 compound treatment 687927.0 118000.0 0.53 612022.0 61600.0 0.31 0.5908 0.9655 1972259 ChemDiv1_004053 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I06 compound treatment 683773.0 114000.0 0.51 620341.0 69900.0 0.35 0.6068 0.9819 1924502 ChemDiv1_004054 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I07 compound treatment 705142.0 136000.0 0.61 676722.0 126000.0 0.63 0.8719 0.9999 1972260 ChemDiv1_004055 C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I08 compound treatment 682167.0 113000.0 0.5 656240.0 106000.0 0.52 0.7274 0.9998 1972261 ChemDiv1_004056 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I09 compound treatment 705715.0 136000.0 0.61 664296.0 114000.0 0.56 0.8302 0.9992 1972262 ChemDiv1_004057 Brc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I10 compound treatment 672225.0 103000.0 0.46 682153.0 132000.0 0.65 0.7867 0.9854 1972263 ChemDiv1_004058 O=C(Nc1nc2c(ccc3ccccc23)o1)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I11 compound treatment 692673.0 123000.0 0.55 699391.0 149000.0 0.74 0.9119 0.9897 1948838 ChemDiv1_004059 FC(F)(F)c1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I12 compound treatment 703599.0 134000.0 0.6 679459.0 129000.0 0.64 0.8766 0.9995 1636058 ChemDiv1_004060 COc1nc(NCc2cccnc2)nc(n1)N3CCSCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I13 compound treatment 714801.0 145000.0 0.65 716409.0 166000.0 0.82 1.0415 0.9933 1197458 ChemDiv1_004061 CCOc1cccc(c1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I14 compound treatment 732349.0 163000.0 0.73 726481.0 176000.0 0.87 1.1323 0.996 1128810 ChemDiv1_004062 CCOc1cc(cc(Br)c1O)C2NC(=O)N(C)C(=C2C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I15 compound treatment 744752.0 175000.0 0.78 745379.0 195000.0 0.97 1.2378 0.9947 1927336 ChemDiv1_004063 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3cc(ccc3C)[N+](=O)[O-])c4cccc(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I16 compound treatment 793051.0 224000.0 1.0 797654.0 247000.0 1.22 1.5738 0.995 1122164 ChemDiv1_004064 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I17 compound treatment 760981.0 192000.0 0.86 739278.0 189000.0 0.94 1.2678 0.9991 1972264 ChemDiv1_004065 CCOC(=O)c1cccc(c1)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I18 compound treatment 703830.0 134000.0 0.6 710370.0 160000.0 0.79 0.9856 0.9908 1972265 ChemDiv1_004066 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I19 compound treatment 4856107.0 4290000.0 19.19 5341036.0 4790000.0 23.73 30.3494 0.9944 1946395 ChemDiv1_004067 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I20 compound treatment 735609.0 166000.0 0.74 762135.0 212000.0 1.05 1.2675 0.9858 1972266 ChemDiv1_004068 [O-][N+](=O)c1ccc(C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I21 compound treatment 792368.0 223000.0 1.0 840522.0 290000.0 1.44 1.7218 0.9841 1317134 ChemDiv1_004069 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I22 compound treatment 686884.0 117000.0 0.53 683104.0 133000.0 0.66 0.8365 0.9939 1599323 ChemDiv1_004070 Brc1ccc(OCc2nnc(NC(=O)C3(CC4CC5CC(C4)C3)C5)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I23 mock treatment 675580.0 106000.0 0.48 685794.0 135000.0 0.67 0.8101 0.9858 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 I24 mock treatment 486855.0 -82600.0 -0.37 234230.0 -316000.0 -1.57 -1.369 -0.8506 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J01 compound treatment 627107.0 57700.0 0.26 551828.0 1400.0 0.01 0.1874 0.7258 1972267 ChemDiv1_004071 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OCCOc3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J02 compound treatment 658170.0 88700.0 0.4 561677.0 11200.0 0.06 0.3202 0.7985 1972268 ChemDiv1_004072 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3cc4NC(CC(n4n3)C(F)(F)F)c5ccco5)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J03 compound treatment 696016.0 127000.0 0.57 626240.0 75800.0 0.38 0.6662 0.9801 1925364 ChemDiv1_004073 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Br)c1OCCOc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J04 compound treatment 693639.0 124000.0 0.56 600070.0 49600.0 0.25 0.567 0.9327 1972269 ChemDiv1_004074 CCOC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc5OCOc5c4)C(F)(F)F)sc6CCCc16 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J05 compound treatment 721909.0 152000.0 0.68 646444.0 96000.0 0.48 0.8189 0.9844 1925297 ChemDiv1_004075 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J06 compound treatment 685502.0 116000.0 0.52 640355.0 89900.0 0.45 0.6824 0.9971 1925323 ChemDiv1_004076 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3ccc(Cl)c(Cl)c3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J07 compound treatment 752517.0 183000.0 0.82 684821.0 134000.0 0.67 1.0502 0.9947 1972270 ChemDiv1_004077 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3ccc(OCCBr)cc3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J08 compound treatment 725983.0 157000.0 0.7 667259.0 117000.0 0.58 0.9047 0.9955 1972271 ChemDiv1_004078 CC(C)c1ccc(C)cc1Oc2cc(NC(=O)c3cnn4C(CC(Nc34)c5ccc(Br)cc5)C(F)(F)F)cc(c2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J09 compound treatment 716276.0 147000.0 0.66 714277.0 164000.0 0.81 1.0387 0.9945 1972272 ChemDiv1_004079 Cc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccccc3F)CC2)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J10 compound treatment 722174.0 153000.0 0.68 703737.0 153000.0 0.76 1.0205 0.9986 1929960 ChemDiv1_004080 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J11 compound treatment 720260.0 151000.0 0.68 738910.0 188000.0 0.93 1.1376 0.9873 1923564 ChemDiv1_004081 Cc1c(Br)c(nn1CC(=O)Nc2cc(ccc2Cl)C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J12 compound treatment 745568.0 176000.0 0.79 700885.0 150000.0 0.75 1.0845 0.9996 1924393 ChemDiv1_004082 Fc1ccc(cc1)C2CC(n3nc(C(=O)N4CCN(Cc5ccccc5)CC4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J13 compound treatment 714288.0 145000.0 0.65 742350.0 192000.0 0.95 1.1308 0.9826 1972273 ChemDiv1_004083 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCCN4CCOCC4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J14 compound treatment 727845.0 158000.0 0.71 730419.0 180000.0 0.89 1.1319 0.9936 1925358 ChemDiv1_004084 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J15 compound treatment 702825.0 133000.0 0.6 740004.0 190000.0 0.94 1.0863 0.9761 1929792 ChemDiv1_004085 COc1ccc(cc1)C2CC(n3nc(C(=O)NCc4ccco4)c(Br)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J16 compound treatment 758373.0 189000.0 0.85 780199.0 230000.0 1.14 1.4029 0.9893 1930421 ChemDiv1_004086 COc1ccc(cc1OC)C2CC(n3nc(C(=O)Nc4ccc(F)cc4F)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J17 compound treatment 815294.0 246000.0 1.1 853150.0 303000.0 1.5 1.8386 0.9884 1972274 ChemDiv1_004087 CC(O)c1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J18 compound treatment 745851.0 176000.0 0.79 744895.0 194000.0 0.96 1.2396 0.9951 1784167 ChemDiv1_004088 Cc1c(Cl)c(nn1CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J19 compound treatment 1010483.0 441000.0 1.97 1011978.0 462000.0 2.29 3.0128 0.9973 1931606 ChemDiv1_004089 CSc1ccccc1NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J20 compound treatment 761967.0 193000.0 0.86 777922.0 227000.0 1.13 1.4063 0.9912 1416027 ChemDiv1_004090 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J21 compound treatment 759507.0 190000.0 0.85 812800.0 262000.0 1.3 1.5207 0.9789 1930268 ChemDiv1_004091 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4cccs4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J22 compound treatment 856611.0 287000.0 1.29 796297.0 246000.0 1.22 1.7702 0.9996 1505306 ChemDiv1_004092 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J23 mock treatment 669227.0 99800.0 0.45 700590.0 150000.0 0.74 0.8418 0.9702 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 J24 mock treatment 211806.0 -358000.0 -1.6 498161.0 -52300.0 -0.26 -1.3151 -0.8109 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K01 compound treatment 611169.0 41700.0 0.19 516926.0 -33500.0 -0.17 0.0147 0.0589 1445027 ChemDiv1_004093 CCOc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K02 compound treatment 637832.0 68400.0 0.31 542086.0 -8340.0 -0.04 0.1872 0.6061 1431787 ChemDiv1_004094 CN1CCN(CC1)c2nc3nonc3nc2Nc4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K03 compound treatment 674546.0 105000.0 0.47 566612.0 16200.0 0.08 0.3894 0.8158 1972275 ChemDiv1_004095 CCCCCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K04 compound treatment 657608.0 88200.0 0.39 570262.0 19800.0 0.1 0.3485 0.857 1925666 ChemDiv1_004096 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K05 compound treatment 665956.0 96500.0 0.43 615528.0 65100.0 0.32 0.5335 0.9896 1972276 ChemDiv1_004097 COc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K06 compound treatment 669491.0 100000.0 0.45 624630.0 74200.0 0.37 0.5766 0.9952 1924471 ChemDiv1_004098 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K07 compound treatment 699827.0 130000.0 0.58 620860.0 70400.0 0.35 0.6594 0.9697 1972277 ChemDiv1_004099 O=C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K08 compound treatment 693135.0 124000.0 0.55 664854.0 114000.0 0.57 0.7923 0.9999 1374228 ChemDiv1_004100 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K09 compound treatment 694898.0 125000.0 0.56 688275.0 138000.0 0.68 0.88 0.9953 1972278 ChemDiv1_004101 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccc(Br)cc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K10 compound treatment 1115942.0 547000.0 2.45 1404853.0 854000.0 4.23 4.7228 0.966 1972279 ChemDiv1_004102 CCN(CC)c1ccc(/C=C\2/Sc3c(ccc4ccccc34)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K11 compound treatment 698242.0 129000.0 0.58 699792.0 149000.0 0.74 0.9309 0.9924 1655566 ChemDiv1_004103 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K12 compound treatment 671079.0 102000.0 0.45 655442.0 105000.0 0.52 0.6896 0.9978 1313445 ChemDiv1_004104 C(Nc1nc(NCc2ccccc2)nc(n1)N3CCOCC3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K13 compound treatment 701940.0 132000.0 0.59 725819.0 175000.0 0.87 1.0338 0.9827 1972280 ChemDiv1_004105 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K14 compound treatment 673915.0 104000.0 0.47 698449.0 148000.0 0.73 0.8492 0.9764 1972281 ChemDiv1_004106 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc4OCOc4cc3Cl)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K15 compound treatment 694143.0 125000.0 0.56 708440.0 158000.0 0.78 0.9482 0.9863 1972282 ChemDiv1_004107 COc1ccc(c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(cc4)S(=O)(=O)N)C)o2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K16 compound treatment 728279.0 159000.0 0.71 713158.0 163000.0 0.81 1.0728 0.998 1536976 ChemDiv1_004108 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K17 compound treatment 790530.0 221000.0 0.99 787273.0 237000.0 1.17 1.5294 0.9964 1972283 ChemDiv1_004109 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccccc3C(=O)O)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K18 compound treatment 757438.0 188000.0 0.84 755156.0 205000.0 1.01 1.3122 0.9957 1166040 ChemDiv1_004110 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)C4CCC(CC4)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K19 compound treatment 735615.0 166000.0 0.74 691342.0 141000.0 0.7 1.0196 0.9995 1972284 ChemDiv1_004111 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(C)cc3[N+](=O)[O-])c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K20 compound treatment 708768.0 139000.0 0.62 688388.0 138000.0 0.68 0.9243 0.999 1972285 ChemDiv1_004112 [O-][N+](=O)c1ccc(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K21 compound treatment 733333.0 164000.0 0.73 743752.0 193000.0 0.96 1.1959 0.9913 1291327 ChemDiv1_004113 COc1ccc(OC)c(Nc2nc3nonc3nc2N4CCCC(C)C4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K22 compound treatment 682529.0 113000.0 0.51 683177.0 133000.0 0.66 0.823 0.9916 1972286 ChemDiv1_004114 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OS(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K23 mock treatment 682293.0 113000.0 0.51 683037.0 133000.0 0.66 0.8217 0.9916 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 K24 mock treatment 206550.0 -363000.0 -1.62 487148.0 -63300.0 -0.31 -1.3703 -0.8283 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L01 compound treatment 631057.0 61600.0 0.28 542019.0 -8410.0 -0.04 0.1656 0.5936 1925377 ChemDiv1_004115 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L02 compound treatment 667601.0 98200.0 0.44 564659.0 14200.0 0.07 0.3605 0.8102 1972287 ChemDiv1_004116 CCOC(=O)c1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccco4)sc5CCCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L03 compound treatment 701222.0 132000.0 0.59 607051.0 56600.0 0.28 0.6155 0.9422 1972288 ChemDiv1_004117 COc1ccccc1OCCOc2c(Br)cc(C=C3C(=O)NC(=S)NC3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L04 compound treatment 688787.0 119000.0 0.53 590275.0 39800.0 0.2 0.5173 0.9083 1972289 ChemDiv1_004118 Cc1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc5OCOc5c4)C(F)(F)F)c(=O)n(c6ccccc6)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L05 compound treatment 695730.0 126000.0 0.57 612247.0 61800.0 0.31 0.6163 0.9585 1972290 ChemDiv1_004119 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L06 compound treatment 687701.0 118000.0 0.53 605721.0 55300.0 0.27 0.568 0.953 1972291 ChemDiv1_004120 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3ccc(Br)cc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L07 compound treatment 716293.0 147000.0 0.66 653612.0 103000.0 0.51 0.8263 0.9923 1948686 ChemDiv1_004121 [O-][N+](=O)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L08 compound treatment 702886.0 133000.0 0.6 661087.0 111000.0 0.55 0.81 0.9991 1972292 ChemDiv1_004122 CN1CCN(CC1)C(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Br)cc4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L09 compound treatment 721990.0 153000.0 0.68 698687.0 148000.0 0.73 1.0022 0.9993 1972293 ChemDiv1_004123 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(F)cc3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L10 compound treatment 707500.0 138000.0 0.62 686815.0 136000.0 0.68 0.9147 0.999 1931602 ChemDiv1_004124 FC(F)(F)C1CC(Nc2cc(nn12)C(=O)Nc3ccc4OCOc4c3)c5ccc(Cl)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L11 compound treatment 704858.0 135000.0 0.61 694443.0 144000.0 0.71 0.9331 0.9967 1972294 ChemDiv1_004125 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N3CCN(CC3)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L12 compound treatment 703076.0 134000.0 0.6 667135.0 117000.0 0.58 0.8318 0.9999 1972295 ChemDiv1_004126 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)NCCCN3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L13 compound treatment 728907.0 159000.0 0.71 708528.0 158000.0 0.78 1.0586 0.9989 1928370 ChemDiv1_004127 COc1ccc(cc1)c2cc(n3nc(C(=O)NCCCn4ccnc4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L14 compound treatment 735906.0 166000.0 0.75 705270.0 155000.0 0.77 1.0693 0.9999 1929893 ChemDiv1_004128 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L15 compound treatment 728257.0 159000.0 0.71 727066.0 177000.0 0.88 1.1214 0.9947 1972296 ChemDiv1_004129 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)N3CCN(Cc4ccccc4)CC3)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L16 compound treatment 728043.0 159000.0 0.71 720142.0 170000.0 0.84 1.0965 0.9965 1925296 ChemDiv1_004130 COc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(OC)c(OC)c4)C(F)(F)F)cc(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L17 compound treatment 750165.0 181000.0 0.81 757635.0 207000.0 1.03 1.2979 0.9931 1972297 ChemDiv1_004131 Fc1ccc(CNC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L18 compound treatment 738153.0 169000.0 0.76 739420.0 189000.0 0.94 1.196 0.9943 1948899 ChemDiv1_004132 Cc1c(Br)c(nn1CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L19 compound treatment 743804.0 174000.0 0.78 734998.0 185000.0 0.91 1.1984 0.9969 1972298 ChemDiv1_004133 CC(NC(=O)c1nn2C(CC(Nc2c1Br)c3cccs3)C(F)(F)F)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L20 compound treatment 703373.0 134000.0 0.6 717800.0 167000.0 0.83 1.0102 0.9873 1286457 ChemDiv1_004134 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L21 compound treatment 723653.0 154000.0 0.69 736035.0 186000.0 0.92 1.1383 0.99 1972299 ChemDiv1_004135 COc1ccc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L22 compound treatment 709227.0 140000.0 0.63 707250.0 157000.0 0.78 0.9918 0.9942 1246789 ChemDiv1_004136 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L23 mock treatment 690951.0 122000.0 0.54 700411.0 150000.0 0.74 0.91 0.9882 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 L24 mock treatment 594930.0 25500.0 0.11 494120.0 -56300.0 -0.28 -0.1166 -0.3868 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M01 compound treatment 631457.0 62000.0 0.28 531705.0 -18700.0 -0.09 0.1307 0.4466 1302769 ChemDiv1_004137 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M02 compound treatment 616657.0 47200.0 0.21 506379.0 -44100.0 -0.22 -0.0049 -0.016 1427833 ChemDiv1_004138 Cc1ccc(Nc2nc3nonc3nc2Nc4ccc(O)cc4)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M03 compound treatment 696488.0 127000.0 0.57 586874.0 36400.0 0.18 0.5298 0.8879 1972300 ChemDiv1_004139 C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M04 compound treatment 671448.0 102000.0 0.46 554664.0 4230.0 0.02 0.3377 0.7388 1167434 ChemDiv1_004140 CCOc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M05 compound treatment 670785.0 101000.0 0.45 608003.0 57600.0 0.29 0.5225 0.975 1972301 ChemDiv1_004141 Brc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M06 compound treatment 687368.0 118000.0 0.53 585504.0 35100.0 0.17 0.4961 0.8927 1972302 ChemDiv1_004142 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M07 compound treatment 681835.0 112000.0 0.5 627523.0 77100.0 0.38 0.6258 0.9908 1972303 ChemDiv1_004143 Cc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M08 compound treatment 694368.0 125000.0 0.56 637006.0 86600.0 0.43 0.6987 0.9914 1508655 ChemDiv1_004144 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(cc3)C(C)(C)C)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M09 compound treatment 699198.0 130000.0 0.58 637065.0 86600.0 0.43 0.7142 0.9889 1972304 ChemDiv1_004145 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccc(Br)cc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M10 compound treatment 694588.0 125000.0 0.56 678927.0 128000.0 0.64 0.8462 0.998 1254762 ChemDiv1_004146 COc1ccc(Cl)cc1C(=O)Nc2ccc(c3nc4cc(Cl)ccc4o3)c(O)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M11 compound treatment 720029.0 151000.0 0.67 672548.0 122000.0 0.6 0.9044 0.9985 1151136 ChemDiv1_004147 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M12 compound treatment 699837.0 130000.0 0.58 658906.0 108000.0 0.54 0.7927 0.9991 1438925 ChemDiv1_004148 C(Nc1nc(nc(n1)N2CCOCC2)N3CCCCC3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M13 compound treatment 704374.0 135000.0 0.6 716729.0 166000.0 0.82 1.0096 0.9884 1232338 ChemDiv1_004149 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M14 compound treatment 709289.0 140000.0 0.63 702124.0 152000.0 0.75 0.974 0.9959 1972305 ChemDiv1_004150 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(COc4c(F)c(F)c(F)c(F)c4F)c3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M15 compound treatment 730347.0 161000.0 0.72 735245.0 185000.0 0.92 1.1567 0.993 1972306 ChemDiv1_004151 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc(Cl)c1OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M16 compound treatment 727560.0 158000.0 0.71 704972.0 155000.0 0.77 1.0418 0.9992 1344009 ChemDiv1_004152 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M17 compound treatment 768878.0 199000.0 0.89 748072.0 198000.0 0.98 1.3236 0.9989 1948909 ChemDiv1_004153 CCOc1c(Br)cc(/C=C\2/N=C(\OC2=O)/C=C/c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M18 compound treatment 714765.0 145000.0 0.65 687828.0 137000.0 0.68 0.9413 0.9997 1972307 ChemDiv1_004154 Cc1c(Br)c(nn1CC(=O)Nc2ccc(Oc3ccc(Cl)cc3)cc2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M19 compound treatment 760148.0 191000.0 0.85 710370.0 160000.0 0.79 1.1639 0.9993 1292810 ChemDiv1_004155 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M20 compound treatment 709560.0 140000.0 0.63 660757.0 110000.0 0.55 0.83 0.9976 1972308 ChemDiv1_004156 CCCCOc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4cc(OC)cc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M21 compound treatment 723898.0 154000.0 0.69 695313.0 145000.0 0.72 0.9964 0.9998 1283174 ChemDiv1_004157 Fc1ccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M22 compound treatment 681575.0 112000.0 0.5 672618.0 122000.0 0.61 0.7829 0.9957 1972309 ChemDiv1_004158 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M23 mock treatment 678626.0 109000.0 0.49 660020.0 110000.0 0.54 0.7295 0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 M24 mock treatment 464954.0 -104000.0 -0.47 416106.0 -134000.0 -0.67 -0.8012 -0.9851 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N01 compound treatment 601664.0 32200.0 0.14 535485.0 -14900.0 -0.07 0.0496 0.3062 1948965 ChemDiv1_004159 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OS(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N02 compound treatment 645397.0 76000.0 0.34 551604.0 1170.0 0.01 0.2445 0.7191 1972310 ChemDiv1_004160 CC(C)OC(=O)c1c(C)c(C)sc1NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N03 compound treatment 649411.0 80000.0 0.36 570478.0 20000.0 0.1 0.3234 0.8704 1948752 ChemDiv1_004161 CC(C)(C)c1ccc(OCCOc2cccc(C=C3C(=O)NC(=S)NC3=O)c2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N04 compound treatment 684141.0 115000.0 0.51 575045.0 24600.0 0.12 0.4493 0.8514 1924389 ChemDiv1_004162 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6ccc7OCOc7c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N05 compound treatment 634247.0 64800.0 0.29 605344.0 54900.0 0.27 0.3975 0.9995 1972311 ChemDiv1_004163 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N06 compound treatment 668031.0 98600.0 0.44 591886.0 41500.0 0.21 0.4573 0.9394 1972312 ChemDiv1_004164 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N3CCN(CC3)C(c4ccccc4)c5ccccc5)c6ccc(Br)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N07 compound treatment 726158.0 157000.0 0.7 634072.0 83600.0 0.41 0.789 0.9684 1972313 ChemDiv1_004165 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccccc3OCCBr)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N08 compound treatment 683463.0 114000.0 0.51 629480.0 79100.0 0.39 0.6378 0.9914 1972314 ChemDiv1_004166 FC(F)(F)C1CC(Nc2c(Cl)c(nn12)C(=O)NCCN3CCOCC3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N09 compound treatment 698535.0 129000.0 0.58 685941.0 136000.0 0.67 0.8833 0.9972 1972315 ChemDiv1_004167 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(F)cc3)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N10 compound treatment 705060.0 136000.0 0.61 671944.0 122000.0 0.6 0.8549 1.0 1925256 ChemDiv1_004168 Cc1c(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccc(Cl)c(Cl)c4)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N11 compound treatment 736170.0 167000.0 0.75 694633.0 144000.0 0.71 1.0329 0.9998 1972316 ChemDiv1_004169 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)Nc3ccncc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N12 compound treatment 704519.0 135000.0 0.6 683192.0 133000.0 0.66 0.8926 0.9991 1925303 ChemDiv1_004170 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Cl)cc4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N13 compound treatment 718378.0 149000.0 0.67 682805.0 132000.0 0.66 0.9351 1.0 1972317 ChemDiv1_004171 Fc1ccc(cc1)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N14 compound treatment 709450.0 140000.0 0.63 701593.0 151000.0 0.75 0.9727 0.9961 1930128 ChemDiv1_004172 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCc4ccccc4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N15 compound treatment 723582.0 154000.0 0.69 748826.0 198000.0 0.98 1.1829 0.985 1972318 ChemDiv1_004173 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCN3CCOCC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N16 compound treatment 703799.0 134000.0 0.6 694428.0 144000.0 0.71 0.9297 0.9964 1925242 ChemDiv1_004174 COc1ccc(cc1OC)C2CC(n3nc(C(=O)N4CCN(CC4)C(=O)c5ccccc5)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N17 compound treatment 757820.0 188000.0 0.84 772967.0 223000.0 1.1 1.3758 0.9912 1930437 ChemDiv1_004175 COc1ccc(NC(=O)c2nn3C(CC(Nc3c2Br)c4cccs4)C(F)(F)F)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N18 compound treatment 721122.0 152000.0 0.68 676965.0 127000.0 0.63 0.9233 0.9992 1784170 ChemDiv1_004176 [O-][N+](=O)c1ncn(CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N19 compound treatment 724027.0 155000.0 0.69 729325.0 179000.0 0.89 1.116 0.9925 1931586 ChemDiv1_004177 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)N3CCCc4ccccc34)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N20 compound treatment 708611.0 139000.0 0.62 714494.0 164000.0 0.81 1.0152 0.9914 1506316 ChemDiv1_004178 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3Cl)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N21 compound treatment 702600.0 133000.0 0.6 680460.0 130000.0 0.64 0.877 0.9992 1935617 ChemDiv1_004179 COc1ccc(cc1)C2CC(n3nc(cc3N2)C(=O)N4CCN(Cc5ccccc5)CC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N22 compound treatment 683468.0 114000.0 0.51 671822.0 121000.0 0.6 0.7861 0.9967 1523266 ChemDiv1_004180 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC)c4ccccc34)c(=O)n2C1c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N23 mock treatment 672928.0 103000.0 0.46 646535.0 96100.0 0.48 0.6642 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 N24 mock treatment 245735.0 -324000.0 -1.45 401690.0 -149000.0 -0.74 -1.5456 -0.9508 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O01 compound treatment 626297.0 56900.0 0.25 537954.0 -12500.0 -0.06 0.1363 0.5203 1650522 ChemDiv1_004181 COc1cc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4s3)cc2)nc(OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O02 compound treatment 633065.0 63600.0 0.28 514025.0 -36400.0 -0.18 0.0739 0.2191 1539968 ChemDiv1_004182 COc1ccccc1Nc2nc3nonc3nc2N4CCCCC4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O03 compound treatment 664923.0 95500.0 0.43 540843.0 -9590.0 -0.05 0.2686 0.6247 1972319 ChemDiv1_004183 CCCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O04 compound treatment 643568.0 74100.0 0.33 558660.0 8230.0 0.04 0.2635 0.7881 1924458 ChemDiv1_004184 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O05 compound treatment 643997.0 74600.0 0.33 595974.0 45500.0 0.23 0.3955 0.9818 1972320 ChemDiv1_004185 CC(C)c1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O06 compound treatment 641948.0 72500.0 0.32 574901.0 24500.0 0.12 0.3152 0.9098 1972321 ChemDiv1_004186 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5cc(ccc5Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O07 compound treatment 663538.0 94100.0 0.42 573230.0 22800.0 0.11 0.3777 0.8661 1972322 ChemDiv1_004187 Clc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3c5ccc(OC(=O)c6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O08 compound treatment 636893.0 67500.0 0.3 572119.0 21700.0 0.11 0.2895 0.9033 1364382 ChemDiv1_004188 CC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O09 compound treatment 686669.0 117000.0 0.52 600637.0 50200.0 0.25 0.5469 0.9418 1972323 ChemDiv1_004189 Brc1ccc(cc1)C(=O)Oc2ccc(cc2)C3Oc4ccccc4C5CC(=NN53)c6ccc(Br)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O10 compound treatment 684306.0 115000.0 0.51 684316.0 134000.0 0.66 0.8326 0.9921 1387498 ChemDiv1_004190 CCN(CC)c1ccc(cc1)c2nc3cc(NC(=O)c4ccc(OC)c(OC)c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O11 compound treatment 722331.0 153000.0 0.68 617941.0 67500.0 0.33 0.7204 0.9458 1681030 ChemDiv1_004191 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O12 compound treatment 665730.0 96300.0 0.43 606974.0 56500.0 0.28 0.5028 0.9782 1972324 ChemDiv1_004192 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3Br)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O13 compound treatment 722174.0 153000.0 0.68 674291.0 124000.0 0.61 0.9173 0.9985 1156745 ChemDiv1_004193 COc1cc(cc(OC)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O14 compound treatment 691342.0 122000.0 0.55 632385.0 82000.0 0.41 0.6729 0.9894 1738244 ChemDiv1_004194 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O15 compound treatment 734304.0 165000.0 0.74 683148.0 133000.0 0.66 0.9867 0.9983 1927357 ChemDiv1_004195 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc(Br)c1OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O16 compound treatment 688319.0 119000.0 0.53 594040.0 43600.0 0.22 0.529 0.9212 1924618 ChemDiv1_004196 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(O)c(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O17 compound treatment 744199.0 175000.0 0.78 673351.0 123000.0 0.61 0.9837 0.9923 1186943 ChemDiv1_004197 Cn1c(SCc2ccccn2)nc3n(C)c(=O)n(C)c(=O)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O18 compound treatment 701022.0 132000.0 0.59 623629.0 73200.0 0.36 0.6729 0.9729 1632083 ChemDiv1_004198 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(OC)ccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O19 compound treatment 725978.0 157000.0 0.7 667236.0 117000.0 0.58 0.9046 0.9955 1972325 ChemDiv1_004199 Cc1cc([N+](=O)[O-])c(cc1Cl)c2ccc(C=c3sc4nc5cc(C)c(C)cc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O20 compound treatment 678832.0 109000.0 0.49 642752.0 92300.0 0.46 0.6696 0.9994 1972326 ChemDiv1_004200 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(C)c([N+](=O)[O-])c4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O21 compound treatment 821465.0 252000.0 1.13 757236.0 207000.0 1.02 1.5221 0.9988 1532775 ChemDiv1_004201 Clc1ccc(Sc2ccccc2C=c3sc4nc5ccccc5n4c3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O22 compound treatment 662154.0 92700.0 0.42 631718.0 81300.0 0.4 0.5782 0.9999 1972327 ChemDiv1_004202 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OS(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O23 mock treatment 685799.0 116000.0 0.52 624598.0 74200.0 0.37 0.6281 0.9854 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 O24 mock treatment 397262.0 -172000.0 -0.77 402329.0 -148000.0 -0.73 -1.0638 -0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P01 compound treatment 608463.0 39000.0 0.17 545115.0 -5310.0 -0.03 0.1049 0.5938 1948343 ChemDiv1_004203 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P02 compound treatment 630052.0 60600.0 0.27 544116.0 -6310.0 -0.03 0.1697 0.6215 1972328 ChemDiv1_004204 COc1ccc(cc1)C2CC(n3ncc(C(=O)Nc4sc5CCCCc5c4C(=O)OC(C)C)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P03 compound treatment 634706.0 65300.0 0.29 577907.0 27500.0 0.14 0.3028 0.9396 1949120 ChemDiv1_004205 CC(C)(C)c1ccc(OCCOc2ccccc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P04 compound treatment 649870.0 80400.0 0.36 569620.0 19200.0 0.1 0.3218 0.8642 1972329 ChemDiv1_004206 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)N(Cc3ccccc3)Cc4ccccc4)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P05 compound treatment 705895.0 136000.0 0.61 680714.0 130000.0 0.65 0.8883 0.9996 1972330 ChemDiv1_004207 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3cccc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P06 compound treatment 665644.0 96200.0 0.43 579034.0 28600.0 0.14 0.4047 0.8927 1972331 ChemDiv1_004208 CCOC(=O)c1c(NC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)sc5CCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P07 compound treatment 657089.0 87600.0 0.39 576864.0 26400.0 0.13 0.37 0.8946 1949010 ChemDiv1_004209 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P08 compound treatment 628508.0 59100.0 0.26 584393.0 34000.0 0.17 0.3059 0.9762 1929910 ChemDiv1_004210 Cc1cc(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(Br)cc4)C(F)(F)F)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P09 compound treatment 662517.0 93100.0 0.42 592854.0 42400.0 0.21 0.4432 0.9498 1972332 ChemDiv1_004211 Fc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccccc3F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P10 compound treatment 658839.0 89400.0 0.4 630394.0 80000.0 0.4 0.5631 1.0 1972333 ChemDiv1_004212 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccco4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P11 compound treatment 700366.0 131000.0 0.59 620421.0 70000.0 0.35 0.6596 0.9686 1778417 ChemDiv1_004213 Cc1cc(nc2cc(nn12)C(=O)Nc3cc(Oc4ccc(O)cc4)cc(c3)[N+](=O)[O-])c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P12 compound treatment 840662.0 271000.0 1.21 793097.0 243000.0 1.2 1.7085 1.0 1930318 ChemDiv1_004214 Cc1c(NC(=O)c2nn3C(CC(Nc3c2Cl)c4ccc(C)cc4)C(F)(F)F)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P13 compound treatment 654655.0 85200.0 0.38 630088.0 79700.0 0.39 0.5488 0.9999 1972334 ChemDiv1_004215 Fc1ccc(cc1)c2cc(n3nc(C(=O)Nc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P14 compound treatment 678961.0 110000.0 0.49 660902.0 110000.0 0.55 0.7336 0.9985 1972335 ChemDiv1_004216 COc1ccc(cc1OC)C2CC(n3nc(C(=O)NCCCn4ccnc4)c(Cl)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P15 compound treatment 646981.0 77500.0 0.35 623572.0 73100.0 0.36 0.5016 0.9998 1972336 ChemDiv1_004217 [O-][N+](=O)c1cc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4cccs4)cc(Oc5ccccc5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P16 compound treatment 796146.0 227000.0 1.01 685556.0 135000.0 0.67 1.1909 0.9796 1972337 ChemDiv1_004218 Cc1ccc(cc1)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P17 compound treatment 694328.0 125000.0 0.56 663209.0 113000.0 0.56 0.7904 1.0 1972338 ChemDiv1_004219 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCc3ccc(Cl)cc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P18 compound treatment 693071.0 124000.0 0.55 632128.0 81700.0 0.4 0.6775 0.9882 1972339 ChemDiv1_004220 OC(c1ccccc1)c2cc(Cl)ccc2NC(=O)c3cnn4C(CC(Nc34)c5cccs5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P19 compound treatment 701746.0 132000.0 0.59 647337.0 96900.0 0.48 0.7582 0.9946 1931476 ChemDiv1_004221 FC(F)(F)C1CC(Nc2c(Br)c(nn12)C(=O)NCCc3ccccc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P20 compound treatment 671121.0 102000.0 0.46 620186.0 69800.0 0.35 0.5662 0.9908 1410172 ChemDiv1_004222 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(OC)c3)c(=O)n2C1c4ccc(OC(=O)C)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P21 compound treatment 656284.0 86800.0 0.39 611635.0 61200.0 0.3 0.4893 0.9924 1972340 ChemDiv1_004223 COc1ccc(cc1)C2CC(n3ncc(C(=O)N4CCN(CC4)C(c5ccccc5)c6ccccc6)c3N2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P22 compound treatment 640959.0 71500.0 0.32 598466.0 48000.0 0.24 0.3946 0.9893 1972341 ChemDiv1_004224 COCCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccccc3)c4ccccc4)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P23 mock treatment 608352.0 38900.0 0.17 592610.0 42200.0 0.21 0.2709 0.9959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.598 P24 mock treatment 400120.0 -169000.0 -0.76 205012.0 -345000.0 -1.71 -1.7459 -0.9329 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A01 compound treatment 581701.0 17300.0 0.08 561305.0 -21200.0 -0.11 -0.0194 -0.1489 1972342 ChemDiv1_004225 CCOc1ccc(OCCSc2nc3ccccc3n2CC(=O)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A02 compound treatment 559712.0 -4660.0 -0.02 546811.0 -35700.0 -0.18 -0.1398 -0.7851 1972343 ChemDiv1_004226 CCOC(=O)COc1ccc2c(=O)c(c3ccccc3OC)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A03 compound treatment 581424.0 17100.0 0.08 551393.0 -31100.0 -0.15 -0.055 -0.32 1949172 ChemDiv1_004227 COc1ccc(cc1OC)c2nc3cc(NC(=O)c4ccc(cc4Cl)[N+](=O)[O-])ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A04 compound treatment 575604.0 11200.0 0.05 572044.0 -10500.0 -0.05 -0.0011 -0.0156 1972344 ChemDiv1_004228 Fc1ccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A05 compound treatment 600365.0 36000.0 0.16 609374.0 26900.0 0.13 0.208 0.9955 1972345 ChemDiv1_004229 COc1cc(/C=C\2/SC(=S)N(C2=O)c3cccc(c3)C(F)(F)F)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A06 compound treatment 653940.0 89600.0 0.4 685001.0 102000.0 0.51 0.6425 0.9932 1357656 ChemDiv1_004230 OC(=O)CC(Nc1nc(nc2ccccc12)c3ccccc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A07 compound treatment 661177.0 96800.0 0.43 634832.0 52300.0 0.26 0.4897 0.9698 1972346 ChemDiv1_004231 Clc1ccccc1COc2cccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A08 compound treatment 642967.0 78600.0 0.35 630776.0 48300.0 0.24 0.4178 0.9823 1944693 ChemDiv1_004232 Clc1cccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A09 compound treatment 1377945.0 814000.0 3.64 1429220.0 847000.0 4.19 5.5411 0.9975 1972347 ChemDiv1_004233 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(OC)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A10 compound treatment 613002.0 48600.0 0.22 626118.0 43600.0 0.22 0.3067 1.0 1950933 ChemDiv1_004234 CN(C)CCOC(=O)CN1C(=O)S/C(=C/c2ccc(Br)cc2)/C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A11 compound treatment 5253247.0 4690000.0 20.99 4885863.0 4300000.0 21.32 29.9157 1.0 1972348 ChemDiv1_004235 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(Cl)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A12 compound treatment 1309850.0 745000.0 3.34 1409304.0 827000.0 4.1 5.2558 0.9948 1972349 ChemDiv1_004236 CCOC(=O)c1c(N/C=C\2/Sc3ccccc3C2=O)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A13 compound treatment 633360.0 69000.0 0.31 637448.0 54900.0 0.27 0.4108 0.998 1972350 ChemDiv1_004237 OC(=O)COc1cccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A14 compound treatment 3114103.0 2550000.0 11.41 2536832.0 1950000.0 9.68 14.9163 0.9966 1972351 ChemDiv1_004238 CC(=O)c1ccc(N/C(=C\2/Sc3ccccc3C2=O)/C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A15 compound treatment 644870.0 80500.0 0.36 640572.0 58100.0 0.29 0.4582 0.9938 1972352 ChemDiv1_004239 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A16 compound treatment 986503.0 422000.0 1.89 942080.0 360000.0 1.78 2.5957 0.9996 1972353 ChemDiv1_004240 CCC(=O)N(/C=C/1\Sc2ccccc2C1=O)c3cccc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A17 compound treatment 679410.0 115000.0 0.51 687672.0 105000.0 0.52 0.7325 1.0 1972354 ChemDiv1_004241 Clc1ccccc1/N=C/2\NC(=O)\C(=C/c3cc4OCOc4cc3Cl)\S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A18 compound treatment 734383.0 170000.0 0.76 690833.0 108000.0 0.54 0.9176 0.9854 1972355 ChemDiv1_004242 [O-][N+](=O)c1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A19 compound treatment 608191.0 43800.0 0.2 603447.0 20900.0 0.1 0.212 0.9556 1562080 ChemDiv1_004243 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5c(F)cccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A20 compound treatment 604377.0 40000.0 0.18 591393.0 8880.0 0.04 0.1577 0.8554 1972356 ChemDiv1_004244 Brc1ccc(cc1)c2nc3sc4CCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A21 compound treatment 589452.0 25100.0 0.11 586528.0 4020.0 0.02 0.0934 0.8196 1972357 ChemDiv1_004245 Cc1nc(SCC(=O)NC2CCCCC2)c3c4CCCCc4sc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A22 compound treatment 579838.0 15500.0 0.07 563732.0 -18800.0 -0.09 -0.0168 -0.1452 1972358 ChemDiv1_004246 CC(C)c1nc2sc(C)c(C)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A23 mock treatment 570421.0 6050.0 0.03 555261.0 -27300.0 -0.14 -0.0763 -0.5543 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 A24 mock treatment 491063.0 -73300.0 -0.33 514840.0 -67700.0 -0.34 -0.4691 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B01 compound treatment 624687.0 60300.0 0.27 573810.0 -8700.0 -0.04 0.1604 0.5868 1364506 ChemDiv1_004247 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3ccccc3Br)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B02 compound treatment 630496.0 66100.0 0.3 578840.0 -3670.0 -0.02 0.1964 0.6624 1972359 ChemDiv1_004248 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc([N+](=O)[O-])c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B03 compound treatment 704123.0 140000.0 0.63 671930.0 89400.0 0.44 0.7556 0.9857 1972360 ChemDiv1_004249 CCOC(=O)c1c(N/C=C\2/N=C(OC2=O)c3ccco3)scc1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B04 compound treatment 678574.0 114000.0 0.51 666006.0 83500.0 0.41 0.6539 0.9945 1972361 ChemDiv1_004250 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc4OCOc4cc3Br)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B05 compound treatment 707707.0 143000.0 0.64 699756.0 117000.0 0.58 0.8644 0.9988 1972362 ChemDiv1_004251 Cc1cc2c(=O)n(c3ccccc3)c(=S)[nH]c2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B06 compound treatment 685682.0 121000.0 0.54 686556.0 104000.0 0.52 0.7484 0.9997 1136653 ChemDiv1_004252 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B07 compound treatment 719133.0 155000.0 0.69 704344.0 122000.0 0.6 0.9166 0.9976 1728289 ChemDiv1_004253 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccccc4Br)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B08 compound treatment 734960.0 171000.0 0.76 720099.0 138000.0 0.68 1.0219 0.9984 1393024 ChemDiv1_004254 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B09 compound treatment 738758.0 174000.0 0.78 747915.0 165000.0 0.82 1.1314 0.9997 1550025 ChemDiv1_004255 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Cl)cc5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B10 compound treatment 747752.0 183000.0 0.82 724348.0 142000.0 0.7 1.0773 0.997 1150805 ChemDiv1_004256 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B11 compound treatment 709482.0 145000.0 0.65 746509.0 164000.0 0.81 1.0338 0.9939 1447214 ChemDiv1_004257 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(Br)c5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B12 compound treatment 1138998.0 575000.0 2.57 1183612.0 601000.0 2.98 3.9244 0.9973 1244184 ChemDiv1_004258 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B13 compound treatment 715347.0 151000.0 0.68 735609.0 153000.0 0.76 1.0141 0.9983 1403876 ChemDiv1_004259 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Br)cc5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B14 compound treatment 719359.0 155000.0 0.69 726891.0 144000.0 0.72 0.9963 0.9999 1123181 ChemDiv1_004260 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)C(=O)OC)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B15 compound treatment 724708.0 160000.0 0.72 761558.0 179000.0 0.89 1.1347 0.9945 1407004 ChemDiv1_004261 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B16 compound treatment 729900.0 166000.0 0.74 727116.0 145000.0 0.72 1.0305 0.9999 1931096 ChemDiv1_004262 COc1ccc2ccccc2c1C3C(=C(C)N=c4sc(=Cc5cc(OC)c(OC)c(OC)c5)c(=O)n34)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B17 compound treatment 719964.0 156000.0 0.7 742013.0 160000.0 0.79 1.0512 0.998 1722363 ChemDiv1_004263 CCCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B18 compound treatment 688570.0 124000.0 0.56 703949.0 121000.0 0.6 0.8185 0.9992 1722870 ChemDiv1_004264 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccnc3)c(=O)n2C1c4c(OC)ccc5ccc(OC)cc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B19 compound treatment 725263.0 161000.0 0.72 700788.0 118000.0 0.59 0.9236 0.9948 1568825 ChemDiv1_004265 CCN(CC)CCn1c(NC(=O)C)nc2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B20 compound treatment 690427.0 126000.0 0.56 683598.0 101000.0 0.5 0.7531 0.9982 1129597 ChemDiv1_004266 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)N2CCN(CC2)c3ccccc3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B21 compound treatment 709012.0 145000.0 0.65 684884.0 102000.0 0.51 0.8164 0.9927 1972363 ChemDiv1_004267 Fc1ccccc1c2nc3sc4CCCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B22 compound treatment 661250.0 96900.0 0.43 638677.0 56200.0 0.28 0.5034 0.977 1944638 ChemDiv1_004268 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCCSCc2ccccc2Cl)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B23 mock treatment 667287.0 103000.0 0.46 637466.0 55000.0 0.27 0.5182 0.9685 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 B24 mock treatment 525095.0 -39300.0 -0.18 521894.0 -60600.0 -0.3 -0.3367 -0.9675 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C01 compound treatment 629764.0 65400.0 0.29 542376.0 -40100.0 -0.2 0.0664 0.1876 1924665 ChemDiv1_004269 CCc1ccc(cc1)c2nn(c3cc(ccc3[N+](=O)[O-])N4CCOCC4)c(=O)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C02 compound treatment 643731.0 79400.0 0.36 603444.0 20900.0 0.1 0.3245 0.8769 1461496 ChemDiv1_004270 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)Nc3cc(C)on3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C03 compound treatment 747689.0 183000.0 0.82 696327.0 114000.0 0.56 0.9789 0.9832 1972364 ChemDiv1_004271 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C04 compound treatment 663232.0 98900.0 0.44 627898.0 45400.0 0.22 0.4719 0.9507 1972365 ChemDiv1_004272 CC/N=C/1\SC(CC(=O)Nc2ccccc2Cl)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C05 compound treatment 710752.0 146000.0 0.66 663018.0 80500.0 0.4 0.7453 0.9717 1563364 ChemDiv1_004273 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C06 compound treatment 671508.0 107000.0 0.48 655692.0 73200.0 0.36 0.5954 0.9905 1972366 ChemDiv1_004274 Cc1c(NC(=O)CCN2C(=O)S/C(=C/c3ccc(C)cc3)/C2=O)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C07 compound treatment 686155.0 122000.0 0.55 694308.0 112000.0 0.55 0.7771 1.0 1972367 ChemDiv1_004275 CCOc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C08 compound treatment 693994.0 130000.0 0.58 688717.0 106000.0 0.53 0.7823 0.9988 1972368 ChemDiv1_004276 COc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C(=O)CCN4C(=O)\C(=C/c5ccc(OC)cc5)\SC4=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C09 compound treatment 745459.0 181000.0 0.81 760843.0 178000.0 0.88 1.1979 0.9991 1972369 ChemDiv1_004277 Brc1cc2OCOc2cc1/C=C\3/S/C(=N/c4ccccc4)/NC3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C10 compound treatment 695419.0 131000.0 0.59 659722.0 77200.0 0.38 0.6852 0.9785 1697070 ChemDiv1_004278 Cc1ccccc1OCc2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C11 compound treatment 850255.0 286000.0 1.28 907023.0 325000.0 1.61 2.0416 0.9936 1972370 ChemDiv1_004279 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C12 compound treatment 692061.0 128000.0 0.57 682443.0 99900.0 0.5 0.7542 0.9974 1972371 ChemDiv1_004280 O=C1/C(=C\NN2CCCCC2)/Sc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C13 compound treatment 704246.0 140000.0 0.63 723973.0 141000.0 0.7 0.9383 0.9984 1972372 ChemDiv1_004281 Fc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C14 compound treatment 899531.0 335000.0 1.5 860684.0 278000.0 1.38 2.0353 0.9991 1972373 ChemDiv1_004282 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C15 compound treatment 707686.0 143000.0 0.64 728290.0 146000.0 0.72 0.9643 0.9983 1972374 ChemDiv1_004283 [O-][N+](=O)c1cc(ccc1Oc2c(Br)cc(/C=C\3/NC(=S)NC3=O)cc2Br)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C16 compound treatment 674334.0 110000.0 0.49 689500.0 107000.0 0.53 0.7228 0.9993 1972375 ChemDiv1_004284 CCC(=O)N(C)/C=C/1\Sc2ccccc2C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C17 compound treatment 728115.0 164000.0 0.73 722850.0 140000.0 0.7 1.0099 0.9997 1972376 ChemDiv1_004285 COc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C18 compound treatment 2101619.0 1540000.0 6.88 1968877.0 1390000.0 6.87 9.7221 1.0 1972377 ChemDiv1_004286 COc1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C19 compound treatment 668095.0 104000.0 0.46 691026.0 109000.0 0.54 0.7084 0.9973 1972378 ChemDiv1_004287 Clc1ccccc1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C20 compound treatment 664859.0 100000.0 0.45 670235.0 87700.0 0.43 0.6253 0.9999 1972379 ChemDiv1_004288 Cc1sc2nc(oc(=O)c2c1C)c3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C21 compound treatment 677454.0 113000.0 0.51 672735.0 90200.0 0.45 0.674 0.9981 1972380 ChemDiv1_004289 Cc1cc2nnc(SCC(=O)Nc3ccccc3F)n2c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C22 compound treatment 647567.0 83200.0 0.37 638131.0 55600.0 0.28 0.4582 0.989 1685242 ChemDiv1_004290 CC(C)(C)c1nc2scc(c3cccs3)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C23 mock treatment 667892.0 104000.0 0.46 630139.0 47600.0 0.24 0.4945 0.951 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 C24 mock treatment 504924.0 -59400.0 -0.27 498841.0 -83700.0 -0.41 -0.4813 -0.9771 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D01 compound treatment 618369.0 54000.0 0.24 580037.0 -2480.0 -0.01 0.1622 0.6704 1433674 ChemDiv1_004291 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3cccc(Br)c3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D02 compound treatment 696885.0 133000.0 0.59 646973.0 64500.0 0.32 0.6452 0.9578 1972381 ChemDiv1_004292 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D03 compound treatment 728131.0 164000.0 0.73 679157.0 96600.0 0.48 0.8569 0.9787 1972382 ChemDiv1_004293 CC/1=NN(C(=O)\C1=C\Nc2cc(Br)ccc2O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D04 compound treatment 698935.0 135000.0 0.6 678036.0 95500.0 0.47 0.7605 0.9929 1972383 ChemDiv1_004294 Clc1cc(Cl)cc(c1)N2C(=O)/C(=C/c3ccc4OCOc4c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D05 compound treatment 728989.0 165000.0 0.74 705662.0 123000.0 0.61 0.9524 0.9956 1972384 ChemDiv1_004295 Cc1ccc(c2csc3[nH]c(=S)[nH]c(=O)c23)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D06 compound treatment 961081.0 397000.0 1.78 1026787.0 444000.0 2.2 2.8119 0.9943 1684781 ChemDiv1_004296 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D07 compound treatment 714246.0 150000.0 0.67 738435.0 156000.0 0.77 1.0206 0.9975 1972385 ChemDiv1_004297 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccccc3Br)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D08 compound treatment 732033.0 168000.0 0.75 736440.0 154000.0 0.76 1.0699 1.0 1185537 ChemDiv1_004298 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D09 compound treatment 757279.0 193000.0 0.86 764006.0 181000.0 0.9 1.2463 0.9998 1510072 ChemDiv1_004299 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4F)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D10 compound treatment 822101.0 258000.0 1.15 903219.0 321000.0 1.59 1.9392 0.9877 1632828 ChemDiv1_004300 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D11 compound treatment 763372.0 199000.0 0.89 745413.0 163000.0 0.81 1.2005 0.9988 1221068 ChemDiv1_004301 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccc(Br)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D12 compound treatment 1037576.0 473000.0 2.12 1254612.0 672000.0 3.33 3.8521 0.9762 1592894 ChemDiv1_004302 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D13 compound treatment 745004.0 181000.0 0.81 750142.0 168000.0 0.83 1.1589 0.9999 1972386 ChemDiv1_004303 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Cl)cc3Cl)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D14 compound treatment 909494.0 345000.0 1.54 960201.0 378000.0 1.87 2.4154 0.9955 1972387 ChemDiv1_004304 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D15 compound treatment 770676.0 206000.0 0.92 763571.0 181000.0 0.9 1.2872 0.9999 1549327 ChemDiv1_004305 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4c(Cl)cccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D16 compound treatment 796094.0 232000.0 1.04 826078.0 244000.0 1.21 1.5866 0.9972 1972388 ChemDiv1_004306 COc1ccc2ccc(OC)c(C=c3sc4=NC(=C(C(c5ccccc5OC)n4c3=O)C(=O)C)C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D17 compound treatment 728692.0 164000.0 0.74 768926.0 186000.0 0.92 1.1731 0.9936 1173148 ChemDiv1_004307 CCCCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D18 compound treatment 728709.0 164000.0 0.74 724218.0 142000.0 0.7 1.0165 0.9997 1972389 ChemDiv1_004308 COc1ccc(cc1)C(=O)NN2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D19 compound treatment 729546.0 165000.0 0.74 745931.0 163000.0 0.81 1.0952 0.999 1141158 ChemDiv1_004309 CN(C)CCCn1c(NC(=O)C)nc2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D20 compound treatment 727017.0 163000.0 0.73 710370.0 128000.0 0.63 0.9627 0.9976 1972390 ChemDiv1_004310 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSc2ccccn2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D21 compound treatment 741329.0 177000.0 0.79 725978.0 143000.0 0.71 1.0627 0.9985 1730319 ChemDiv1_004311 Cc1cccc(c1)c2nc3sc4CCCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D22 compound treatment 716804.0 152000.0 0.68 689741.0 107000.0 0.53 0.8581 0.9923 1781251 ChemDiv1_004312 [O-][N+](=O)c1cccc(c1)N(CC(=O)N(Cc2ccccc2)Cc3ccccc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D23 mock treatment 679812.0 115000.0 0.52 678846.0 96300.0 0.48 0.7028 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 D24 mock treatment 211827.0 -353000.0 -1.58 538696.0 -43800.0 -0.22 -1.2694 -0.7969 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E01 compound treatment 843019.0 279000.0 1.25 785541.0 203000.0 1.01 1.5932 0.9943 1972391 ChemDiv1_004313 OC(=O)c1cc(NC(=O)c2cccc(c2)N3C(=O)c4cccc5c(ccc(C3=O)c45)[N+](=O)[O-])cc(c1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E02 compound treatment 629702.0 65300.0 0.29 605934.0 23400.0 0.12 0.2888 0.918 1639906 ChemDiv1_004314 COc1cc(cc(OC)c1OC)c2cc(nc(SCC(=O)Nc3ncccn3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E03 compound treatment 684399.0 120000.0 0.54 666600.0 84100.0 0.42 0.6745 0.9921 1375823 ChemDiv1_004315 Cc1cc(C)n(n1)c2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E04 compound treatment 660132.0 95800.0 0.43 656034.0 73500.0 0.36 0.5606 0.9967 1972392 ChemDiv1_004316 CC/N=C\1/SC(CC(=O)Nc2cccc(c2)C(F)(F)F)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E05 compound treatment 729403.0 165000.0 0.74 694329.0 112000.0 0.55 0.914 0.9899 1784721 ChemDiv1_004317 COc1ccc(c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E06 compound treatment 672177.0 108000.0 0.48 710548.0 128000.0 0.63 0.7897 0.9909 1936624 ChemDiv1_004318 CCOC(=O)c1ccc(NC(=O)CCCN2C(=O)/C(=C/c3ccc(OC)cc3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E07 compound treatment 687720.0 123000.0 0.55 728874.0 146000.0 0.73 0.9031 0.991 1944202 ChemDiv1_004319 [O-][N+](=O)c1ccc(Cl)c(c1)c2ccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E08 compound treatment 830465.0 266000.0 1.19 829139.0 247000.0 1.22 1.7062 0.9999 1947414 ChemDiv1_004320 [O-][N+](=O)c1cc2OCOc2cc1/C=C/3\SC(=S)N(NC(=O)c4ccccc4Cl)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E09 compound treatment 743690.0 179000.0 0.8 761913.0 179000.0 0.89 1.196 0.9987 1972393 ChemDiv1_004321 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E10 compound treatment 723522.0 159000.0 0.71 740265.0 158000.0 0.78 1.0563 0.9989 1972394 ChemDiv1_004322 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccc(Cl)cc3Cl)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E11 compound treatment 779009.0 215000.0 0.96 836957.0 254000.0 1.26 1.5707 0.991 1972395 ChemDiv1_004323 COc1ccc2ccccc2c1/C=C\3/S/C(=N/c4ccccc4)/NC3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E12 compound treatment 721381.0 157000.0 0.7 776626.0 194000.0 0.96 1.1769 0.9881 1972396 ChemDiv1_004324 Clc1ncccc1C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E13 compound treatment 713617.0 149000.0 0.67 760267.0 178000.0 0.88 1.095 0.9907 1972397 ChemDiv1_004325 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1Oc5nc(nc(n5)N6CCOCC6)N7CCOCC7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E14 compound treatment 1038893.0 475000.0 2.12 1049208.0 467000.0 2.31 3.1368 0.9991 1972398 ChemDiv1_004326 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E15 compound treatment 785964.0 222000.0 0.99 791853.0 209000.0 1.04 1.4347 0.9998 1972399 ChemDiv1_004327 Clc1ccc(COc2ccc(/C=C\3/NC(=S)NC3=O)cc2)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E16 compound treatment 726968.0 163000.0 0.73 744314.0 162000.0 0.8 1.0814 0.9988 1972400 ChemDiv1_004328 CCC(=O)N(Cc1ccccc1)/C=C/2\Sc3ccccc3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E17 compound treatment 748768.0 184000.0 0.83 788566.0 206000.0 1.02 1.3054 0.9944 1972401 ChemDiv1_004329 COc1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E18 compound treatment 685357.0 121000.0 0.54 702569.0 120000.0 0.59 0.8035 0.9989 1972402 ChemDiv1_004330 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E19 compound treatment 714389.0 150000.0 0.67 706982.0 124000.0 0.62 0.9108 0.9991 1972403 ChemDiv1_004331 Clc1ccc(Cn2cc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E20 compound treatment 718271.0 154000.0 0.69 719465.0 137000.0 0.68 0.9669 1.0 1381477 ChemDiv1_004332 O=c1oc(nc2scc(c3cccs3)c12)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E21 compound treatment 717866.0 153000.0 0.69 707843.0 125000.0 0.62 0.9249 0.9987 1972404 ChemDiv1_004333 O=C1N(CSc2ncnc3sc4CCCCc4c23)C(=O)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E22 compound treatment 683256.0 119000.0 0.53 678373.0 95900.0 0.47 0.7121 0.9984 1972405 ChemDiv1_004334 Cc1sc2nc(oc(=O)c2c1C)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E23 mock treatment 680335.0 116000.0 0.52 663018.0 80500.0 0.4 0.649 0.9915 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 E24 mock treatment 515618.0 -48800.0 -0.22 510588.0 -71900.0 -0.36 -0.4063 -0.9723 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F01 compound treatment 659289.0 94900.0 0.42 584755.0 2240.0 0.01 0.3083 0.7253 1972406 ChemDiv1_004335 CCOC(=O)c1c(C)n(c2ccc(C)cc2C)c3ccc(OC(=O)/C=C/c4ccccc4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F02 compound treatment 793220.0 229000.0 1.02 712468.0 130000.0 0.64 1.1796 0.9749 1928991 ChemDiv1_004336 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F03 compound treatment 694133.0 130000.0 0.58 680138.0 97600.0 0.48 0.7527 0.9959 1972407 ChemDiv1_004337 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F04 compound treatment 1185532.0 621000.0 2.78 1280352.0 698000.0 3.46 4.4106 0.9942 1494558 ChemDiv1_004338 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F05 compound treatment 726754.0 162000.0 0.73 705059.0 123000.0 0.61 0.9432 0.996 1972408 ChemDiv1_004339 Brc1ccc(cc1)c2csc3[nH]c(=S)[nH]c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F06 compound treatment 713121.0 149000.0 0.67 695198.0 113000.0 0.56 0.8655 0.9962 1487022 ChemDiv1_004340 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(C)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F07 compound treatment 734159.0 170000.0 0.76 743701.0 161000.0 0.8 1.102 0.9997 1659447 ChemDiv1_004341 CC1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F08 compound treatment 1.4301713E7 1.37E7 61.49 1.3522235E7 1.29E7 64.1 88.8086 0.9998 1507573 ChemDiv1_004342 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F09 compound treatment 744653.0 180000.0 0.81 750965.0 168000.0 0.83 1.1607 0.9999 1678240 ChemDiv1_004343 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(F)c4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F10 compound treatment 867027.0 303000.0 1.35 949075.0 367000.0 1.82 2.242 0.9896 1282868 ChemDiv1_004344 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F11 compound treatment 768369.0 204000.0 0.91 768730.0 186000.0 0.92 1.298 1.0 1972409 ChemDiv1_004345 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Br)cc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F12 compound treatment 1799681.0 1240000.0 5.53 2196991.0 1610000.0 8.0 9.5654 0.9838 1440544 ChemDiv1_004346 CCOC(=O)C1=C(C)N=c2sc(=Cc3c(C)[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F13 compound treatment 715888.0 152000.0 0.68 759705.0 177000.0 0.88 1.1003 0.9919 1253520 ChemDiv1_004347 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F14 compound treatment 752828.0 188000.0 0.84 766586.0 184000.0 0.91 1.2413 0.9992 1972410 ChemDiv1_004348 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F15 compound treatment 758731.0 194000.0 0.87 785306.0 203000.0 1.0 1.3256 0.9974 1256488 ChemDiv1_004349 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3c(Cl)cccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F16 compound treatment 748518.0 184000.0 0.82 766215.0 184000.0 0.91 1.2264 0.9988 1292167 ChemDiv1_004350 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(O)c3)c(=O)n2C1c4cc(Br)c(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F17 compound treatment 634143.0 69800.0 0.31 629476.0 47000.0 0.23 0.3853 0.9895 1327163 ChemDiv1_004351 COc1cc2nc3n(CCC(C)C)c4ccccc4c3nc2cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F18 compound treatment 725896.0 162000.0 0.72 719487.0 137000.0 0.68 0.9911 0.9995 1172234 ChemDiv1_004352 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(F)c(Cl)c2)S(=O)(=O)c3ccc(SC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F19 compound treatment 735284.0 171000.0 0.77 731965.0 149000.0 0.74 1.0645 0.9999 1727978 ChemDiv1_004353 Cc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCN4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F20 compound treatment 706225.0 142000.0 0.63 708507.0 126000.0 0.62 0.8903 1.0 1972411 ChemDiv1_004354 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSc2ccc(Cl)cc2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F21 compound treatment 719970.0 156000.0 0.7 734383.0 152000.0 0.75 1.0245 0.9993 1972412 ChemDiv1_004355 Cc1ccccc1c2nc3sc4CCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F22 compound treatment 698778.0 134000.0 0.6 691585.0 109000.0 0.54 0.8075 0.9986 1120902 ChemDiv1_004356 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(C)cc3)S(=O)(=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F23 mock treatment 692341.0 128000.0 0.57 687333.0 105000.0 0.52 0.7722 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 F24 mock treatment 298509.0 -266000.0 -1.19 496706.0 -85800.0 -0.43 -1.1421 -0.9037 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G01 compound treatment 651326.0 87000.0 0.39 602758.0 20200.0 0.1 0.3461 0.8612 1470580 ChemDiv1_004357 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc3C(=O)N(C(=O)c4cccc2c43)c5cccc(O)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G02 compound treatment 654965.0 90600.0 0.41 618230.0 35700.0 0.18 0.4119 0.9309 1191919 ChemDiv1_004358 Cc1ccc(cc1)c2cc(nc(SCC(=O)Nc3ncccn3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G03 compound treatment 1173706.0 609000.0 2.73 1242191.0 660000.0 3.27 4.2395 0.996 1972413 ChemDiv1_004359 COc1cc(/C=C\2/SC(=S)N(CC=C)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G04 compound treatment 694078.0 130000.0 0.58 654788.0 72300.0 0.36 0.6637 0.973 1972414 ChemDiv1_004360 [O-][N+](=O)c1ccc2NC(=O)/C(=C/3\SC(=S)N(NC(=O)c4cccnc4)C3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G05 compound treatment 1028801.0 464000.0 2.08 972169.0 390000.0 1.93 2.835 0.9993 1972415 ChemDiv1_004361 COc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G06 compound treatment 672844.0 108000.0 0.49 701777.0 119000.0 0.59 0.7611 0.9953 1972416 ChemDiv1_004362 [O-][N+](=O)c1ccccc1C(=O)NN2C(=O)/C(=C/c3ccc(Br)cc3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G07 compound treatment 739239.0 175000.0 0.78 741996.0 159000.0 0.79 1.1121 1.0 1972417 ChemDiv1_004363 COc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G08 compound treatment 711402.0 147000.0 0.66 705637.0 123000.0 0.61 0.8967 0.9993 1972418 ChemDiv1_004364 Brc1ccc2NC(=O)/C(=C/3\SC(=S)N(NS(=O)(=O)c4ccccc4)C3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G09 compound treatment 930933.0 367000.0 1.64 957361.0 375000.0 1.86 2.4733 0.9981 1972419 ChemDiv1_004365 CCOc1cc(cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c1O)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G10 compound treatment 685658.0 121000.0 0.54 746035.0 164000.0 0.81 0.9567 0.9811 1972420 ChemDiv1_004366 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\NC(=S)N(C3=O)c4ccccc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G11 compound treatment 786919.0 223000.0 1.0 793723.0 211000.0 1.05 1.4443 0.9997 1972421 ChemDiv1_004367 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G12 compound treatment 719331.0 155000.0 0.69 716282.0 134000.0 0.66 0.9591 0.9997 1972422 ChemDiv1_004368 COc1cc(cc(OC)c1OC)C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G13 compound treatment 742030.0 178000.0 0.8 737787.0 155000.0 0.77 1.1062 0.9999 1972423 ChemDiv1_004369 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCCOc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G14 compound treatment 2240257.0 1680000.0 7.5 2090819.0 1510000.0 7.47 10.588 1.0 1972424 ChemDiv1_004370 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccccc3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G15 compound treatment 837952.0 274000.0 1.22 885537.0 303000.0 1.5 1.9274 0.9949 1972425 ChemDiv1_004371 CCOc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G16 compound treatment 8814988.0 8250000.0 36.93 7369544.0 6790000.0 33.62 49.8896 0.9989 1972426 ChemDiv1_004372 COc1ccccc1N(C=O)/C=C/2\Sc3ccccc3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G17 compound treatment 789224.0 225000.0 1.01 813218.0 231000.0 1.14 1.5198 0.998 1972427 ChemDiv1_004373 CCOc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G18 compound treatment 704210.0 140000.0 0.63 715655.0 133000.0 0.66 0.909 0.9997 1121995 ChemDiv1_004374 COc1ccccc1c2nc3sc4CCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G19 compound treatment 776651.0 212000.0 0.95 797884.0 215000.0 1.07 1.4263 0.9983 1972428 ChemDiv1_004375 OC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G20 compound treatment 673910.0 110000.0 0.49 698435.0 116000.0 0.57 0.7528 0.9969 1972429 ChemDiv1_004376 Cc1nc2scc(c3ccc(Br)cc3)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G21 compound treatment 733255.0 169000.0 0.76 735822.0 153000.0 0.76 1.0716 1.0 1924034 ChemDiv1_004377 COC(=O)CCN1C(=O)/C(=C/c2ccc(OCc3ccc(Cl)cc3)c(OC)c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G22 compound treatment 673873.0 109000.0 0.49 670072.0 87600.0 0.43 0.6533 0.9981 1972430 ChemDiv1_004378 Cc1cc2c(=O)oc(nc2s1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G23 mock treatment 682138.0 118000.0 0.53 665318.0 82800.0 0.41 0.6628 0.9923 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 G24 mock treatment 499784.0 -64600.0 -0.29 503039.0 -79500.0 -0.39 -0.4828 -0.9885 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H01 compound treatment 638613.0 74200.0 0.33 571895.0 -10600.0 -0.05 0.1978 0.5879 1972431 ChemDiv1_004379 CCOC(=O)c1c(C)n(c2ccc(C)c(C)c2)c3ccc(OC(=O)c4ccccc4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H02 compound treatment 672594.0 108000.0 0.48 625602.0 43100.0 0.21 0.4935 0.9322 1948670 ChemDiv1_004380 CC1=NN(C(=O)C1/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H03 compound treatment 725699.0 161000.0 0.72 679898.0 97400.0 0.48 0.8518 0.9808 1972432 ChemDiv1_004381 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H04 compound treatment 1487345.0 923000.0 4.13 1740433.0 1160000.0 5.74 6.9775 0.987 1689219 ChemDiv1_004382 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H05 compound treatment 721985.0 158000.0 0.71 692558.0 110000.0 0.55 0.8844 0.9919 1972433 ChemDiv1_004383 Cc1sc2[nH]c(=S)[nH]c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H06 compound treatment 713211.0 149000.0 0.67 746914.0 164000.0 0.81 1.047 0.995 1222639 ChemDiv1_004384 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H07 compound treatment 739227.0 175000.0 0.78 775739.0 193000.0 0.96 1.2303 0.995 1191951 ChemDiv1_004385 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H08 compound treatment 774531.0 210000.0 0.94 764842.0 182000.0 0.9 1.3039 0.9998 1465669 ChemDiv1_004386 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(cc4)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H09 compound treatment 757391.0 193000.0 0.86 756181.0 174000.0 0.86 1.2193 1.0 1685916 ChemDiv1_004387 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(F)c5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H10 compound treatment 829388.0 265000.0 1.19 897231.0 315000.0 1.56 1.9413 0.9909 1565170 ChemDiv1_004388 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H11 compound treatment 710192.0 146000.0 0.65 732705.0 150000.0 0.74 0.9877 0.9979 1358843 ChemDiv1_004389 CCN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H12 compound treatment 734584.0 170000.0 0.76 848998.0 266000.0 1.32 1.4722 0.9659 1195996 ChemDiv1_004390 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H13 compound treatment 750778.0 186000.0 0.83 763813.0 181000.0 0.9 1.2251 0.9993 1489629 ChemDiv1_004391 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H14 compound treatment 731077.0 167000.0 0.75 741802.0 159000.0 0.79 1.0856 0.9996 1972434 ChemDiv1_004392 O=C/1N(Cc2ccccc2)\C(=N/Cc3ccccc3)\S\C1=C/c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H15 compound treatment 754377.0 190000.0 0.85 771003.0 188000.0 0.93 1.2617 0.9989 1215521 ChemDiv1_004393 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5c(Cl)cccc5Cl)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H16 compound treatment 840955.0 277000.0 1.24 868752.0 286000.0 1.42 1.8781 0.9977 1972435 ChemDiv1_004394 CCOc1cc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H17 compound treatment 726635.0 162000.0 0.73 736805.0 154000.0 0.76 1.0541 0.9997 1478760 ChemDiv1_004395 Cc1cc(C)c2n(CC(O)CN3C(=O)c4ccccc4S3(=O)=O)c(c(c5ccccc5)c2c1)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H18 compound treatment 719669.0 155000.0 0.7 731854.0 149000.0 0.74 1.0147 0.9995 1374726 ChemDiv1_004396 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H19 compound treatment 730231.0 166000.0 0.74 738221.0 156000.0 0.77 1.0704 0.9998 1361970 ChemDiv1_004397 Clc1ccc(Cn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H20 compound treatment 718394.0 154000.0 0.69 659042.0 76500.0 0.38 0.7556 0.9603 1972436 ChemDiv1_004398 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2ccc(Cl)cc2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H21 compound treatment 707655.0 143000.0 0.64 728466.0 146000.0 0.72 0.9648 0.9982 1972437 ChemDiv1_004399 Cc1ccc(cc1)S(=O)(=O)Oc2ccccc2/C=C/3\N=C(OC3=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H22 compound treatment 710187.0 146000.0 0.65 707323.0 125000.0 0.62 0.8987 0.9996 1972438 ChemDiv1_004400 COc1ccc(N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H23 mock treatment 697112.0 133000.0 0.59 670449.0 87900.0 0.44 0.7282 0.9884 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 H24 mock treatment 301535.0 -263000.0 -1.18 546474.0 -36000.0 -0.18 -0.9582 -0.8052 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I01 compound treatment 638913.0 74500.0 0.33 580263.0 -2250.0 -0.01 0.2281 0.6831 1305861 ChemDiv1_004401 OC(=O)c1cc(Br)ccc1NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I02 compound treatment 745056.0 181000.0 0.81 666784.0 84300.0 0.42 0.8671 0.9527 1972439 ChemDiv1_004402 CCOc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I03 compound treatment 825880.0 262000.0 1.17 717091.0 135000.0 0.67 1.2992 0.9644 1972440 ChemDiv1_004403 COc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I04 compound treatment 687520.0 123000.0 0.55 650440.0 67900.0 0.34 0.6277 0.972 1972441 ChemDiv1_004404 CC(=O)N1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(O)cc3)C2=O)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I05 compound treatment 711821.0 147000.0 0.66 682892.0 100000.0 0.5 0.8183 0.9903 1972442 ChemDiv1_004405 CCOc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I06 compound treatment 704961.0 141000.0 0.63 682621.0 100000.0 0.5 0.7957 0.993 1972443 ChemDiv1_004406 Brc1ccc(CC2S/C(=N/c3ccccc3)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I07 compound treatment 764787.0 200000.0 0.9 735906.0 153000.0 0.76 1.1717 0.9966 1972444 ChemDiv1_004407 COc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I08 compound treatment 730177.0 166000.0 0.74 671798.0 89300.0 0.44 0.8376 0.9694 1972445 ChemDiv1_004408 Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I09 compound treatment 789682.0 225000.0 1.01 779003.0 196000.0 0.97 1.4014 0.9998 1972446 ChemDiv1_004409 COc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I10 compound treatment 1179272.0 615000.0 2.75 1125904.0 543000.0 2.69 3.8498 0.9999 1972447 ChemDiv1_004410 Clc1ccc(Cl)c(c1)c2ccc(/C=C/3\NC(=S)N(C3=O)c4ccccc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I11 compound treatment 725503.0 161000.0 0.72 724653.0 142000.0 0.7 1.0079 0.9999 1972448 ChemDiv1_004411 COc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I12 compound treatment 776002.0 212000.0 0.95 797205.0 215000.0 1.06 1.4219 0.9983 1972449 ChemDiv1_004412 CC(=O)Oc1ccc(cc1/C=C/2\Sc3ccccc3C2=O)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I13 compound treatment 687961.0 124000.0 0.55 736794.0 154000.0 0.76 0.9316 0.9874 1972450 ChemDiv1_004413 [O-][N+](=O)c1ccc(Oc2cccc(/C=C\3/NC(=S)NC3=O)c2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I14 compound treatment 1121572.0 557000.0 2.49 1107589.0 525000.0 2.6 3.603 0.9998 1972451 ChemDiv1_004414 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I15 compound treatment 740316.0 176000.0 0.79 748432.0 166000.0 0.82 1.1381 0.9998 1972452 ChemDiv1_004415 [O-][N+](=O)c1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I16 compound treatment 6898347.0 6330000.0 28.35 7632398.0 7050000.0 34.92 44.7436 0.9947 1972453 ChemDiv1_004416 O=CN(/C=C/1\Sc2ccccc2C1=O)c3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I17 compound treatment 752934.0 189000.0 0.84 740522.0 158000.0 0.78 1.1503 0.9993 1972454 ChemDiv1_004417 OC(=O)COc1cccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I18 compound treatment 717123.0 153000.0 0.68 699254.0 117000.0 0.58 0.8924 0.9965 1972455 ChemDiv1_004418 COc1ccc(cc1)c2csc3nc(oc(=O)c23)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I19 compound treatment 719508.0 155000.0 0.69 734589.0 152000.0 0.75 1.0237 0.9992 1474215 ChemDiv1_004419 C=CCn1c(SCC(=O)c2cccs2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I20 compound treatment 713986.0 150000.0 0.67 670766.0 88300.0 0.44 0.7827 0.9786 1972456 ChemDiv1_004420 Cc1sc2nc(C)oc(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I21 compound treatment 694663.0 130000.0 0.58 702795.0 120000.0 0.6 0.8337 0.9999 1268616 ChemDiv1_004421 Brc1ccccc1Oc2coc3cc(OC(=O)c4ccco4)ccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I22 compound treatment 673679.0 109000.0 0.49 660264.0 77800.0 0.39 0.6183 0.993 1972457 ChemDiv1_004422 Cc1cc2c(=O)oc(nc2s1)c3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I23 mock treatment 673732.0 109000.0 0.49 666236.0 83700.0 0.41 0.6394 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 I24 mock treatment 558161.0 -6210.0 -0.03 532609.0 -49900.0 -0.25 -0.1945 -0.7817 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J01 compound treatment 651630.0 87300.0 0.39 592384.0 9870.0 0.05 0.3108 0.7895 1725277 ChemDiv1_004423 CCOC(=O)c1c(C)n(c2ccccc2C)c3ccc(OC(=O)c4ccccc4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J02 compound treatment 750836.0 186000.0 0.83 703410.0 121000.0 0.6 1.0137 0.9867 1972458 ChemDiv1_004424 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(C)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J03 compound treatment 721208.0 157000.0 0.7 682143.0 99600.0 0.49 0.8454 0.9851 1972459 ChemDiv1_004425 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccccc3)C)scc1c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J04 compound treatment 703912.0 140000.0 0.62 679439.0 96900.0 0.48 0.7812 0.9916 1404479 ChemDiv1_004426 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J05 compound treatment 732488.0 168000.0 0.75 703763.0 121000.0 0.6 0.9569 0.9938 1972460 ChemDiv1_004427 CCOC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J06 compound treatment 706883.0 143000.0 0.64 706014.0 124000.0 0.61 0.8837 0.9998 1266930 ChemDiv1_004428 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J07 compound treatment 717951.0 154000.0 0.69 731011.0 148000.0 0.74 1.0063 0.9994 1590946 ChemDiv1_004429 Cn1c(=O)n(C)c2nc(NCc3ccco3)n(Cc4ccccc4Br)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J08 compound treatment 1012617.0 448000.0 2.01 945178.0 363000.0 1.8 2.6892 0.9985 1200045 ChemDiv1_004430 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4ccc(cc4)C(=O)O)c(=O)n2C1c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J09 compound treatment 757659.0 193000.0 0.87 754802.0 172000.0 0.85 1.2153 1.0 1208663 ChemDiv1_004431 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(F)cc5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J10 compound treatment 702728.0 138000.0 0.62 735261.0 153000.0 0.76 0.973 0.9951 1684224 ChemDiv1_004432 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J11 compound treatment 735777.0 171000.0 0.77 682631.0 100000.0 0.5 0.8932 0.9777 1359181 ChemDiv1_004433 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J12 compound treatment 702288.0 138000.0 0.62 750276.0 168000.0 0.83 1.0242 0.9893 1658381 ChemDiv1_004434 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J13 compound treatment 737250.0 173000.0 0.77 768057.0 186000.0 0.92 1.1971 0.9963 1227802 ChemDiv1_004435 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccc(Cl)cc4Cl)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J14 compound treatment 905636.0 341000.0 1.53 954888.0 372000.0 1.84 2.3846 0.9956 1200293 ChemDiv1_004436 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5cc(Br)c(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J15 compound treatment 728318.0 164000.0 0.73 763728.0 181000.0 0.9 1.1537 0.995 1186646 ChemDiv1_004437 Cn1c(=O)n(C)c2nc(NCCc3ccccc3)n(Cc4c(F)cccc4Cl)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J16 compound treatment 736603.0 172000.0 0.77 760795.0 178000.0 0.88 1.1697 0.9977 1972461 ChemDiv1_004438 COc1ccc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J17 compound treatment 781933.0 218000.0 0.97 773159.0 191000.0 0.94 1.3564 0.9999 1611579 ChemDiv1_004439 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(O)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J18 compound treatment 730795.0 166000.0 0.74 734720.0 152000.0 0.75 1.0599 1.0 1568461 ChemDiv1_004440 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J19 compound treatment 717304.0 153000.0 0.68 730745.0 148000.0 0.73 1.0033 0.9994 1972462 ChemDiv1_004441 CCOC(=O)CSc1nc2cc(C)ccc2[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J20 compound treatment 734752.0 170000.0 0.76 709226.0 127000.0 0.63 0.9832 0.9953 1972463 ChemDiv1_004442 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2cccc(Cl)c2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J21 compound treatment 738062.0 174000.0 0.78 758369.0 176000.0 0.87 1.1658 0.9984 1972464 ChemDiv1_004443 Clc1ccc(cc1)N2C(=O)/C(=C/c3cc4OCOc4cc3Br)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J22 compound treatment 697022.0 133000.0 0.59 677602.0 95100.0 0.47 0.753 0.9934 1783361 ChemDiv1_004444 COc1ccc(N(CC(=O)NCc2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J23 mock treatment 698435.0 134000.0 0.6 697869.0 115000.0 0.57 0.8284 0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 J24 mock treatment 348979.0 -215000.0 -0.96 513460.0 -69100.0 -0.34 -0.9237 -0.9028 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K01 compound treatment 626801.0 62400.0 0.28 567512.0 -15000.0 -0.07 0.1451 0.5016 1972465 ChemDiv1_004445 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K02 compound treatment 657026.0 92700.0 0.41 609186.0 26700.0 0.13 0.3867 0.8884 1972466 ChemDiv1_004446 COC(=O)c1ccc(/C=C/2\SC(=S)N(NC(=O)c3ccc(Br)cc3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K03 compound treatment 710987.0 147000.0 0.66 642825.0 60300.0 0.3 0.6753 0.9365 1944052 ChemDiv1_004447 Fc1ccc(COc2ccc(Br)cc2/C=C\3/SC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K04 compound treatment 691045.0 127000.0 0.57 647437.0 64900.0 0.32 0.6284 0.9639 1927063 ChemDiv1_004448 COc1ccc(/C=C\2/SC(=NC2=O)N3CCN(CC3)C(=O)CN4C(=O)S\C(=C/c5ccccc5F)\C4=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K05 compound treatment 697924.0 134000.0 0.6 652062.0 69500.0 0.34 0.6663 0.9657 1972467 ChemDiv1_004449 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1OCc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K06 compound treatment 703481.0 139000.0 0.62 643451.0 60900.0 0.3 0.6538 0.9447 1972468 ChemDiv1_004450 Cc1ccccc1CC2S/C(=N/c3ccc(Br)cc3)/NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K07 compound treatment 753463.0 189000.0 0.85 717555.0 135000.0 0.67 1.0716 0.9932 1972469 ChemDiv1_004451 CCOc1cc(/C=C\2/SC(=O)N(C2=O)c3ccc(Cl)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K08 compound treatment 705905.0 142000.0 0.63 694203.0 112000.0 0.55 0.8392 0.9977 1972470 ChemDiv1_004452 CN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(Cl)cc4)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K09 compound treatment 1.5664748E7 1.51E7 67.6 1.6077175E7 1.55E7 76.76 102.0726 0.998 1972471 ChemDiv1_004453 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc(Br)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K10 compound treatment 742378.0 178000.0 0.8 699340.0 117000.0 0.58 0.9727 0.9877 1972472 ChemDiv1_004454 COC(=O)C1=C(C)N=c2sc(=Cc3cccc(c3)[N+](=O)[O-])c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K11 compound treatment 916162.0 352000.0 1.57 927702.0 345000.0 1.71 2.3227 0.9992 1972473 ChemDiv1_004455 CCOc1ccc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K12 compound treatment 712916.0 149000.0 0.66 758105.0 176000.0 0.87 1.0853 0.9912 1972474 ChemDiv1_004456 [O-][N+](=O)c1ccc(o1)C(=O)Oc2ccccc2/C=C/3\Sc4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K13 compound treatment 760897.0 197000.0 0.88 723577.0 141000.0 0.7 1.1162 0.9935 1447438 ChemDiv1_004457 COc1cc(C=O)ccc1Oc2nc(nc(n2)N3CCCCC3)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K14 compound treatment 740987.0 177000.0 0.79 723957.0 141000.0 0.7 1.0545 0.9982 1972475 ChemDiv1_004458 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K15 compound treatment 733289.0 169000.0 0.76 742784.0 160000.0 0.79 1.0961 0.9997 1972476 ChemDiv1_004459 [O-][N+](=O)c1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K16 compound treatment 1299774.0 735000.0 3.29 1291717.0 709000.0 3.51 4.812 0.9995 1972477 ChemDiv1_004460 CC(=O)N(/C=C/1\Sc2ccccc2C1=O)c3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K17 compound treatment 762473.0 198000.0 0.89 765346.0 183000.0 0.91 1.2675 0.9999 1972478 ChemDiv1_004461 CCOc1ccc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K18 compound treatment 698338.0 134000.0 0.6 640623.0 58100.0 0.29 0.6276 0.9435 1972479 ChemDiv1_004462 Clc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K19 compound treatment 723072.0 159000.0 0.71 657393.0 74900.0 0.37 0.7646 0.9541 1972480 ChemDiv1_004463 COc1ccc(cc1OC)c2nc3sc4CCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K20 compound treatment 708784.0 144000.0 0.65 652062.0 69500.0 0.34 0.7007 0.9566 1647504 ChemDiv1_004464 CCc1nc2sc3CCCCc3c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K21 compound treatment 726415.0 162000.0 0.73 678465.0 96000.0 0.48 0.849 0.979 1972481 ChemDiv1_004465 COc1ccccc1c2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K22 compound treatment 679353.0 115000.0 0.51 664946.0 82400.0 0.41 0.6527 0.9934 1505504 ChemDiv1_004466 Cc1ccc(cc1)c2csc3nc(Cc4ccccc4)oc(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K23 mock treatment 719815.0 155000.0 0.7 657654.0 75100.0 0.37 0.7552 0.957 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 K24 mock treatment 524496.0 -39900.0 -0.18 526787.0 -55700.0 -0.28 -0.3214 -0.9777 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L01 compound treatment 631069.0 66700.0 0.3 595198.0 12700.0 0.06 0.2555 0.8376 1334632 ChemDiv1_004467 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3ccc(OC(=O)C#Cc4ccccc4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L02 compound treatment 725035.0 161000.0 0.72 652080.0 69600.0 0.34 0.7522 0.9432 1948497 ChemDiv1_004468 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(F)cc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L03 compound treatment 719905.0 156000.0 0.7 634986.0 52500.0 0.26 0.6761 0.9098 1972482 ChemDiv1_004469 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccc(C)cc3)C)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L04 compound treatment 980956.0 417000.0 1.86 971807.0 389000.0 1.93 2.6822 0.9999 1670085 ChemDiv1_004470 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L05 compound treatment 708351.0 144000.0 0.64 684797.0 102000.0 0.51 0.814 0.9929 1972483 ChemDiv1_004471 NNC(=O)CSc1nc2scc(c3ccccc3)c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L06 compound treatment 714325.0 150000.0 0.67 688250.0 106000.0 0.52 0.845 0.9925 1130488 ChemDiv1_004472 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L07 compound treatment 726076.0 162000.0 0.72 714150.0 132000.0 0.65 0.9729 0.9986 1343629 ChemDiv1_004473 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4cccc(Br)c4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L08 compound treatment 798069.0 234000.0 1.05 736378.0 154000.0 0.76 1.2787 0.9879 1725771 ChemDiv1_004474 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(OC)cc3OC)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L09 compound treatment 734943.0 171000.0 0.76 714992.0 132000.0 0.66 1.004 0.9972 1463143 ChemDiv1_004475 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccccc4Br)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L10 compound treatment 1138648.0 574000.0 2.57 1264462.0 682000.0 3.38 4.2065 0.9909 1524465 ChemDiv1_004476 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N(C)C)c(=O)n2C1c4c(OC)ccc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L11 compound treatment 755026.0 191000.0 0.85 735267.0 153000.0 0.76 1.1385 0.9982 1714209 ChemDiv1_004477 Cn1c(=O)n(C)c2nc(NCc3ccco3)n(Cc4ccc(Br)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L12 compound treatment 1277014.0 713000.0 3.19 1293033.0 711000.0 3.52 4.7446 0.9988 1704027 ChemDiv1_004478 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L13 compound treatment 718271.0 154000.0 0.69 747006.0 164000.0 0.81 1.0633 0.9965 1188386 ChemDiv1_004479 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccc(Cl)cc5Cl)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L14 compound treatment 2945269.0 2380000.0 10.66 2953915.0 2370000.0 11.75 15.8429 0.9988 1931218 ChemDiv1_004480 CCN(CC)c1ccc(C=c2sc3=NC(=C(C(c4ccc(OC)cc4OC)n3c2=O)C(=O)C)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L15 compound treatment 716617.0 152000.0 0.68 776095.0 194000.0 0.96 1.16 0.986 1508793 ChemDiv1_004481 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc6ccccc56)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L16 compound treatment 2292687.0 1730000.0 7.74 2601542.0 2020000.0 10.0 12.543 0.9919 1972484 ChemDiv1_004482 COc1ccc2ccccc2c1C3C(=C(C)N=c4sc(=Cc5ccc(cc5)N(C)C)c(=O)n34)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L17 compound treatment 709951.0 146000.0 0.65 758272.0 176000.0 0.87 1.0765 0.9898 1972485 ChemDiv1_004483 CC(=O)Nc1nc2ccccc2n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L18 compound treatment 704416.0 140000.0 0.63 708701.0 126000.0 0.63 0.8853 1.0 1972486 ChemDiv1_004484 CCOc1ccc(cc1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L19 compound treatment 679506.0 115000.0 0.52 726787.0 144000.0 0.71 0.8698 0.9871 1972487 ChemDiv1_004485 Brc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L20 compound treatment 719814.0 155000.0 0.7 703707.0 121000.0 0.6 0.9165 0.9973 1972488 ChemDiv1_004486 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)NCCSCc2ccccc2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L21 compound treatment 730850.0 166000.0 0.75 718672.0 136000.0 0.67 1.0039 0.9988 1972489 ChemDiv1_004487 COc1cc(OC)c(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L22 compound treatment 667065.0 103000.0 0.46 682365.0 99900.0 0.49 0.6748 0.9993 1783360 ChemDiv1_004488 COc1ccc(N(CC(=O)NCc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L23 mock treatment 675023.0 111000.0 0.5 664017.0 81500.0 0.4 0.6357 0.9949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 L24 mock treatment 498747.0 -65600.0 -0.29 544463.0 -38000.0 -0.19 -0.341 -0.977 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M01 compound treatment 642364.0 78000.0 0.35 571624.0 -10900.0 -0.05 0.2087 0.5908 1972490 ChemDiv1_004489 OC(=O)c1ccc(NC(=O)CCN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M02 compound treatment 675779.0 111000.0 0.5 606841.0 24300.0 0.12 0.4378 0.8534 1972491 ChemDiv1_004490 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(NC(=O)c4ccccc4[N+](=O)[O-])C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M03 compound treatment 717087.0 153000.0 0.68 633281.0 50800.0 0.25 0.6612 0.9078 1972492 ChemDiv1_004491 CCOc1cc(/C=C\2/SC(=O)NC2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M04 compound treatment 679550.0 115000.0 0.52 615933.0 33400.0 0.17 0.4816 0.8894 1972493 ChemDiv1_004492 Cc1cccc(/N=C/2\NC(=O)\C(=C/3\C(=O)Nc4ccc(Br)cc34)\S2)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M05 compound treatment 716192.0 152000.0 0.68 645376.0 62900.0 0.31 0.7007 0.9374 1972494 ChemDiv1_004493 CN1C(=O)N(C)C(=O)C(=Cc2cc(Br)ccc2OCc3ccccc3)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M06 compound treatment 669301.0 105000.0 0.47 640219.0 57700.0 0.29 0.5343 0.9717 1972495 ChemDiv1_004494 Clc1ccc(CC2S/C(=N/c3ccc(Cl)cc3)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M07 compound treatment 735537.0 171000.0 0.77 685220.0 103000.0 0.51 0.9015 0.9802 1972496 ChemDiv1_004495 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccccc3)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M08 compound treatment 714727.0 150000.0 0.67 680196.0 97700.0 0.48 0.8181 0.9869 1972497 ChemDiv1_004496 Oc1ccc2c(=O)c(c3ccccc3Cl)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M09 compound treatment 1011055.0 447000.0 2.0 934650.0 352000.0 1.74 2.6474 0.9977 1972498 ChemDiv1_004497 Oc1ccc(Br)cc1/C=C\2/S/C(=N/c3ccccc3)/NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M10 compound treatment 725574.0 161000.0 0.72 672024.0 89500.0 0.44 0.8238 0.9727 1972499 ChemDiv1_004498 [O-][N+](=O)c1cccc(N/C=C\2/Sc3ccccc3C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M11 compound treatment 764994.0 201000.0 0.9 742728.0 160000.0 0.79 1.1962 0.9981 1972500 ChemDiv1_004499 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M12 compound treatment 694783.0 130000.0 0.58 670217.0 87700.0 0.43 0.72 0.9894 1972501 ChemDiv1_004500 C/C(=C/1\Sc2ccccc2C1=O)/NC3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M13 compound treatment 757159.0 193000.0 0.86 697334.0 115000.0 0.57 1.0124 0.9795 1511652 ChemDiv1_004501 COc1cc(C=O)ccc1Oc2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M14 compound treatment 1616231.0 1050000.0 4.71 1640832.0 1060000.0 5.24 7.0366 0.9986 1972502 ChemDiv1_004502 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc(O)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M15 compound treatment 747811.0 183000.0 0.82 736300.0 154000.0 0.76 1.1193 0.9993 1972503 ChemDiv1_004503 COc1cc(/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M16 compound treatment 708809.0 144000.0 0.65 682110.0 99600.0 0.49 0.8061 0.9911 1972504 ChemDiv1_004504 CN(/C=C/1\Sc2ccccc2C1=O)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M17 compound treatment 770067.0 206000.0 0.92 710966.0 128000.0 0.64 1.101 0.9837 1972505 ChemDiv1_004505 Brc1ccc(OCc2cccc3ccccc23)c(/C=C\4/NC(=S)NC4=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M18 compound treatment 717491.0 153000.0 0.69 679635.0 97100.0 0.48 0.8249 0.985 1972506 ChemDiv1_004506 Brc1cccc(c1)c2nc3scc(c4ccccc4)c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M19 compound treatment 749373.0 185000.0 0.83 698586.0 116000.0 0.58 0.9922 0.9841 1972507 ChemDiv1_004507 Fc1ccc(cc1)c2csc3nc(SCC(=O)Nc4ccc5OCOc5c4)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M20 compound treatment 709132.0 145000.0 0.65 678569.0 96100.0 0.48 0.7947 0.9885 1972508 ChemDiv1_004508 CCc1nc2scc(c3ccc(Br)cc3)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M21 compound treatment 736547.0 172000.0 0.77 695509.0 113000.0 0.56 0.9408 0.9877 1972509 ChemDiv1_004509 COc1ccccc1c2c(oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M22 compound treatment 785549.0 221000.0 0.99 695198.0 113000.0 0.56 1.0948 0.9632 1972510 ChemDiv1_004510 O=c1oc(CCCCc2nc3sc4CCCCc4c3c(=O)o2)nc5sc6CCCCc6c15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M23 mock treatment 680719.0 116000.0 0.52 658263.0 75800.0 0.38 0.6336 0.9871 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 M24 mock treatment 488352.0 -76000.0 -0.34 389662.0 -193000.0 -0.96 -0.9162 -0.9034 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N01 compound treatment 647793.0 83400.0 0.37 583496.0 983.0 0.0 0.2675 0.7163 1458021 ChemDiv1_004511 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N02 compound treatment 685040.0 121000.0 0.54 598971.0 16500.0 0.08 0.4396 0.8047 1972511 ChemDiv1_004512 COc1cc(ccc1c2ccc(/C=C/3\C(=O)NC(=S)N(C3=O)c4ccccc4)o2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N03 compound treatment 691209.0 127000.0 0.57 652128.0 69600.0 0.34 0.6453 0.9714 1972512 ChemDiv1_004513 CCOC(=O)c1c(N/C=C/2\C(=NN(C2=O)c3ccc(C)cc3)C)sc(C)c1c4ccc5cc(OC)ccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N04 compound treatment 687794.0 123000.0 0.55 634886.0 52400.0 0.26 0.5741 0.9406 1447307 ChemDiv1_004514 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)C(=O)OC)c(=O)n2C1c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N05 compound treatment 703748.0 139000.0 0.62 664717.0 82200.0 0.41 0.7291 0.9786 1972513 ChemDiv1_004515 CC/1=NN(C(=O)\C1=C/Nc2cc(cc(c2O)C(C)(C)C)C(C)(C)C)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N06 compound treatment 716857.0 152000.0 0.68 683269.0 101000.0 0.5 0.8356 0.9882 1972514 ChemDiv1_004516 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N07 compound treatment 690976.0 127000.0 0.57 665464.0 83000.0 0.41 0.6913 0.9875 1510773 ChemDiv1_004517 CC1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N08 compound treatment 8454358.0 7890000.0 35.32 7607048.0 7020000.0 34.8 49.58 1.0 1286217 ChemDiv1_004518 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N09 compound treatment 741637.0 177000.0 0.79 725034.0 143000.0 0.71 1.0603 0.9983 1457126 ChemDiv1_004519 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5ccccc5Br)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N10 compound treatment 1531784.0 967000.0 4.33 1557174.0 975000.0 4.83 6.4762 0.9985 1570438 ChemDiv1_004520 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N(C)C)c(=O)n2C1c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N11 compound treatment 724185.0 160000.0 0.72 713338.0 131000.0 0.65 0.9641 0.9988 1469965 ChemDiv1_004521 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(Cc4ccc(Br)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N12 compound treatment 686522.0 122000.0 0.55 714330.0 132000.0 0.65 0.8484 0.9961 1702217 ChemDiv1_004522 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N13 compound treatment 699604.0 135000.0 0.61 686009.0 103000.0 0.51 0.7906 0.9966 1972515 ChemDiv1_004523 Cn1c(=O)n(C)c2nc(NCCOCCO)n(Cc3ccc(Cl)c(Cl)c3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N14 compound treatment 1260036.0 696000.0 3.11 1268604.0 686000.0 3.4 4.6053 0.999 1972516 ChemDiv1_004524 COc1ccc(C2C(=C(C)N=c3sc(=Cc4cc(C)n(c4C)c5ccccc5)c(=O)n23)C(=O)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N15 compound treatment 731565.0 167000.0 0.75 706138.0 124000.0 0.61 0.9622 0.995 1218930 ChemDiv1_004525 CCn1c2ccccc2c3nc4cc(OC)c(OC)cc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N16 compound treatment 743288.0 179000.0 0.8 730352.0 148000.0 0.73 1.0842 0.999 1972517 ChemDiv1_004526 COc1ccc(C=c2sc3=NC(=C(C(c4c(OC)ccc5ccccc45)n3c2=O)C(=O)C)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N17 compound treatment 696800.0 132000.0 0.59 705472.0 123000.0 0.61 0.8499 0.9999 1232486 ChemDiv1_004527 CC(=O)Nc1nc2ccccc2n1Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N18 compound treatment 717070.0 153000.0 0.68 680287.0 97800.0 0.48 0.8258 0.9858 1972518 ChemDiv1_004528 CCOc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(SC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N19 compound treatment 733980.0 170000.0 0.76 685259.0 103000.0 0.51 0.8968 0.9811 1701332 ChemDiv1_004529 Clc1ccc(OCc2nc3ccccc3c(=O)n2c4ccc(Br)cn4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N20 compound treatment 768210.0 204000.0 0.91 705292.0 123000.0 0.61 1.0753 0.9806 1972519 ChemDiv1_004530 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N21 compound treatment 693056.0 129000.0 0.58 705441.0 123000.0 0.61 0.8379 0.9996 1972520 ChemDiv1_004531 CCOc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(OCC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N22 compound treatment 690348.0 126000.0 0.56 640785.0 58300.0 0.29 0.6029 0.9516 1972521 ChemDiv1_004532 COc1ccc(Cl)cc1N(CC(=O)NCc2ccccn2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N23 mock treatment 650993.0 86600.0 0.39 671181.0 88700.0 0.44 0.5848 0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 N24 mock treatment 500935.0 -63400.0 -0.28 158027.0 -424000.0 -2.1 -1.6877 -0.7954 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O01 compound treatment 654033.0 89700.0 0.4 567162.0 -15400.0 -0.08 0.23 0.5631 1201459 ChemDiv1_004533 OC(=O)c1cc(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)cc(c1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O02 compound treatment 652340.0 88000.0 0.39 583926.0 1410.0 0.01 0.2834 0.7196 1942909 ChemDiv1_004534 CCOc1ccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O03 compound treatment 693679.0 129000.0 0.58 620528.0 38000.0 0.19 0.5424 0.8912 1972522 ChemDiv1_004535 Oc1c(Br)cc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)[N+](=O)[O-])cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O04 compound treatment 671836.0 107000.0 0.48 584784.0 2270.0 0.01 0.3481 0.7234 1972523 ChemDiv1_004536 Cc1ccc(/N=C/2\NC(=O)\C(=C/3\C(=O)Nc4ccc(Br)cc34)\S2)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O05 compound treatment 712415.0 148000.0 0.66 634051.0 51500.0 0.26 0.6491 0.914 1972524 ChemDiv1_004537 Clc1ccc(COc2ccccc2/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O06 compound treatment 670263.0 106000.0 0.47 618670.0 36200.0 0.18 0.4618 0.9114 1972525 ChemDiv1_004538 Brc1ccc(CC2S/C(=N/c3ccccn3)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O07 compound treatment 845738.0 281000.0 1.26 734634.0 152000.0 0.75 1.4235 0.9698 1972526 ChemDiv1_004539 CCOc1cc(/C=C\2/SC(=S)N(CC(=O)O)C2=O)ccc1Oc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O08 compound treatment 708185.0 144000.0 0.64 632202.0 49700.0 0.25 0.6293 0.913 1972527 ChemDiv1_004540 CN1CCN(Cc2c(O)ccc3c(=O)c(c4ccccc4Cl)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O09 compound treatment 4108377.0 3540000.0 15.86 3730596.0 3150000.0 15.59 22.2451 1.0 1972528 ChemDiv1_004541 Oc1c(Cl)cc(Br)cc1/C=C\2/S/C(=N/c3ccccc3)/NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O10 compound treatment 887044.0 323000.0 1.44 769226.0 187000.0 0.92 1.6754 0.9768 1972529 ChemDiv1_004542 O=C1/C(=C\Nc2cccnc2)/Sc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O11 compound treatment 777628.0 213000.0 0.95 706567.0 124000.0 0.61 1.1096 0.9773 1972530 ChemDiv1_004543 CCOc1cc(/C=C\2/S/C(=N/c3ccccc3)/NC2=O)ccc1OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O12 compound treatment 1616475.0 1050000.0 4.71 1360765.0 778000.0 3.86 6.0563 0.9951 1972531 ChemDiv1_004544 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O13 compound treatment 725268.0 161000.0 0.72 669627.0 87100.0 0.43 0.8144 0.97 1972532 ChemDiv1_004545 COc1cc(/C=C\2/NC(=S)NC2=O)cc(Br)c1OC(=O)C3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O14 compound treatment 796133.0 232000.0 1.04 806832.0 224000.0 1.11 1.5193 0.9994 1972533 ChemDiv1_004546 C/C(=C/1\Sc2ccccc2C1=O)/Nc3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O15 compound treatment 748419.0 184000.0 0.82 705039.0 123000.0 0.61 1.0117 0.9887 1972534 ChemDiv1_004547 COc1ccccc1/C=C\2/S/C(=N/c3ccccc3Cl)/NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O16 compound treatment 2062664.0 1500000.0 6.71 1664842.0 1080000.0 5.36 8.5338 0.9938 1972535 ChemDiv1_004548 COc1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O17 compound treatment 731188.0 167000.0 0.75 653989.0 71500.0 0.35 0.7784 0.9419 1972536 ChemDiv1_004549 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2OS(=O)(=O)c3ccccc3[N+](=O)[O-])C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O18 compound treatment 677017.0 113000.0 0.5 643846.0 61300.0 0.3 0.5714 0.9706 1972537 ChemDiv1_004550 Cc1ccc(cc1)c2csc3nc(oc(=O)c23)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O19 compound treatment 715315.0 151000.0 0.68 647911.0 65400.0 0.32 0.7069 0.9433 1522963 ChemDiv1_004551 c1ccc(cc1)c2nnc(n3nnc4ccccc34)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O20 compound treatment 684209.0 120000.0 0.54 617308.0 34800.0 0.17 0.5012 0.8895 1472035 ChemDiv1_004552 CCc1nc2scc(c3cccs3)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O21 compound treatment 706893.0 143000.0 0.64 653122.0 70600.0 0.35 0.6984 0.96 1923861 ChemDiv1_004553 COc1ccccc1c2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O22 compound treatment 673717.0 109000.0 0.49 606033.0 23500.0 0.12 0.4285 0.8516 1463297 ChemDiv1_004554 CCOC(=O)c1c(C)n(c2ccc(I)cc2)c3ccc(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O23 mock treatment 685512.0 121000.0 0.54 617439.0 34900.0 0.17 0.5058 0.8886 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 O24 mock treatment 247389.0 -317000.0 -1.42 195956.0 -387000.0 -1.91 -2.3574 -0.9891 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P01 compound treatment 592850.0 28500.0 0.13 555683.0 -26800.0 -0.13 -0.0038 -0.0209 1972538 ChemDiv1_004555 CCOC(=O)c1c(N/C=C/2\N=C(OC2=O)c3ccccc3)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P02 compound treatment 645302.0 80900.0 0.36 585870.0 3360.0 0.02 0.2679 0.7388 1972539 ChemDiv1_004556 COc1cc(/C=C/2\Sc3ccccc3C2=O)c(Br)cc1OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P03 compound treatment 620194.0 55800.0 0.25 576212.0 -6300.0 -0.03 0.1546 0.614 1444873 ChemDiv1_004557 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)scc1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P04 compound treatment 634093.0 69700.0 0.31 593572.0 11100.0 0.05 0.2594 0.8187 1249662 ChemDiv1_004558 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P05 compound treatment 622450.0 58100.0 0.26 581642.0 -871.0 0.0 0.1808 0.6953 1218907 ChemDiv1_004559 Cn1c(=O)n(C)c2nc(N3CCN(Cc4ccccc4)CC3)n(Cc5cccc(Cl)c5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P06 compound treatment 653537.0 89200.0 0.4 598978.0 16500.0 0.08 0.3399 0.8344 1565872 ChemDiv1_004560 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(SC)cc3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P07 compound treatment 690946.0 127000.0 0.57 602487.0 20000.0 0.1 0.4706 0.8182 1548199 ChemDiv1_004561 Cn1c(=O)n(C)c2nc(NCc3ccc4OCOc4c3)n(Cc5cccc(Cl)c5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P08 compound treatment 767391.0 203000.0 0.91 689761.0 107000.0 0.53 1.0183 0.9673 1614452 ChemDiv1_004562 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P09 compound treatment 658542.0 94200.0 0.42 623415.0 40900.0 0.2 0.4413 0.9436 1690412 ChemDiv1_004563 COc1ccc(CCNc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P10 compound treatment 669435.0 105000.0 0.47 608836.0 26300.0 0.13 0.4248 0.8703 1204469 ChemDiv1_004564 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(SC)cc3)c(=O)n2C1c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P11 compound treatment 672304.0 108000.0 0.48 615317.0 32800.0 0.16 0.4565 0.8956 1643100 ChemDiv1_004565 Cn1c(=O)n(C)c2nc(NCCc3ccccc3)n(Cc4ccc(Br)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P12 compound treatment 760945.0 197000.0 0.88 678455.0 95900.0 0.48 0.9583 0.9582 1325001 ChemDiv1_004566 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(CC=C)c4ccccc34)c(=O)n2C1c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P13 compound treatment 638846.0 74500.0 0.33 601980.0 19500.0 0.1 0.3039 0.8758 1339246 ChemDiv1_004567 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P14 compound treatment 1344345.0 780000.0 3.49 1296371.0 714000.0 3.54 4.9694 1.0 1209999 ChemDiv1_004568 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OCC)c3)c(=O)n2C1c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P15 compound treatment 639168.0 74800.0 0.33 590792.0 8280.0 0.04 0.2657 0.7878 1648069 ChemDiv1_004569 COc1cc2nc3n(C(C)C)c4ccccc4c3nc2cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P16 compound treatment 677892.0 114000.0 0.51 619206.0 36700.0 0.18 0.4878 0.904 1972540 ChemDiv1_004570 COc1ccccc1C2C(=C(C)N=c3sc(=Cc4cc(OC)c(OC)c(OC)c4)c(=O)n23)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P17 compound treatment 678980.0 115000.0 0.51 626821.0 44300.0 0.22 0.518 0.9282 1409228 ChemDiv1_004571 CC(=O)Nc1nc2ccccc2n1Cc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P18 compound treatment 654202.0 89800.0 0.4 637149.0 54600.0 0.27 0.4757 0.9814 1204228 ChemDiv1_004572 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P19 compound treatment 660187.0 95800.0 0.43 619596.0 37100.0 0.18 0.4332 0.9284 1938153 ChemDiv1_004573 CC1CCc2c(C1)sc3nc(oc(=O)c23)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P20 compound treatment 632202.0 67800.0 0.3 633406.0 50900.0 0.25 0.393 0.9957 1972541 ChemDiv1_004574 [O-][N+](=O)c1cccc(c1)N(CC(=O)NCCSCc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P21 compound treatment 640219.0 75800.0 0.34 606375.0 23900.0 0.12 0.3237 0.9003 1972542 ChemDiv1_004575 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(cc1OC)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P22 compound treatment 603353.0 39000.0 0.17 602532.0 20000.0 0.1 0.1935 0.9642 1949649 ChemDiv1_004576 COc1ccc(Cl)cc1N(CC(=O)N2CCC(C)CC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P23 mock treatment 647632.0 83300.0 0.37 582787.0 274.0 0.0 0.2645 0.7097 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.599 P24 mock treatment 422796.0 -142000.0 -0.63 434050.0 -148000.0 -0.74 -0.9682 -0.9973 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A01 compound treatment 560476.0 6150.0 0.03 547696.0 -36900.0 -0.18 -0.1096 -0.5937 1951696 ChemDiv1_004577 COc1ccc(Cl)cc1N(CC(=O)NCCCC(C)(C)C2OCCO2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A02 compound treatment 569734.0 15400.0 0.07 539410.0 -45100.0 -0.22 -0.1093 -0.4672 1972543 ChemDiv1_004578 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(Br)c(OC)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A03 compound treatment 577188.0 22900.0 0.1 551308.0 -33200.0 -0.16 -0.0441 -0.2272 1972544 ChemDiv1_004579 C1C2CC3CC1CC(C2)C3Nc4nc5nonc5nc4NC6C7CC8CC(C7)CC6C8 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A04 compound treatment 568281.0 14000.0 0.06 542937.0 -41600.0 -0.21 -0.1016 -0.4716 1972545 ChemDiv1_004580 O=C1N(CSc2nnc(o2)c3ccco3)c4ccccc4C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A05 compound treatment 620050.0 65700.0 0.29 582826.0 -1720.0 -0.01 0.202 0.6863 1168209 ChemDiv1_004581 COc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)ccc1OC(C)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A06 compound treatment 601893.0 47600.0 0.21 576171.0 -8380.0 -0.04 0.1212 0.5588 1972546 ChemDiv1_004582 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\c3cccnc3)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A07 compound treatment 620239.0 65900.0 0.3 609201.0 24700.0 0.12 0.295 0.9238 1972547 ChemDiv1_004583 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(cc4C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A08 compound treatment 621576.0 67300.0 0.3 614056.0 29500.0 0.15 0.3162 0.9449 1972548 ChemDiv1_004584 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A09 compound treatment 637478.0 83200.0 0.37 615552.0 31000.0 0.15 0.3718 0.9234 1972549 ChemDiv1_004585 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A10 compound treatment 673336.0 119000.0 0.53 659600.0 75100.0 0.37 0.6396 0.9845 1972550 ChemDiv1_004586 Fc1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A11 compound treatment 610910.0 56600.0 0.25 600141.0 15600.0 0.08 0.2337 0.8826 1972551 ChemDiv1_004587 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A12 compound treatment 604218.0 49900.0 0.22 605607.0 21100.0 0.1 0.2317 0.9399 1972552 ChemDiv1_004588 OC(=O)CN1C(=O)/C(=C/2\SC(=NC2=O)Nc3cccc(Cl)c3Cl)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A13 compound treatment 605896.0 51600.0 0.23 621620.0 37100.0 0.18 0.2931 0.9936 1972553 ChemDiv1_004589 COC(=O)c1ccc(NC(=O)CSc2nnc(C)c3ccccc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A14 compound treatment 641134.0 86800.0 0.39 620389.0 35800.0 0.18 0.4003 0.937 1972554 ChemDiv1_004590 COc1ccc(NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A15 compound treatment 634619.0 80300.0 0.36 634201.0 49700.0 0.25 0.4281 0.9829 1595733 ChemDiv1_004591 Cc1nn(CC(=O)Nc2ccc(cc2)S(=O)(=O)N)c(=O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A16 compound treatment 619882.0 65600.0 0.29 625019.0 40500.0 0.2 0.3493 0.9827 1972555 ChemDiv1_004592 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)N6CCCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A17 compound treatment 630335.0 76000.0 0.34 613665.0 29100.0 0.14 0.3426 0.927 1570540 ChemDiv1_004593 COc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A18 compound treatment 621828.0 67500.0 0.3 621332.0 36800.0 0.18 0.3425 0.9707 1972556 ChemDiv1_004594 CCOC(=O)CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A19 compound treatment 628956.0 74600.0 0.33 630035.0 45500.0 0.23 0.3956 0.9816 1972557 ChemDiv1_004595 COc1cc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)ccc1OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A20 compound treatment 576154.0 21800.0 0.1 585870.0 1320.0 0.01 0.0737 0.7528 1972558 ChemDiv1_004596 Cc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A21 compound treatment 600746.0 46400.0 0.21 598480.0 13900.0 0.07 0.1957 0.8939 1946655 ChemDiv1_004597 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A22 compound treatment 573772.0 19500.0 0.09 580714.0 -3830.0 -0.02 0.0481 0.5402 1972559 ChemDiv1_004598 Cc1onc(c1C(=O)Nc2nnc(s2)c3cccc(c3)[N+](=O)[O-])c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A23 mock treatment 561890.0 7570.0 0.03 559950.0 -24600.0 -0.12 -0.0622 -0.4919 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 A24 mock treatment 276294.0 -278000.0 -1.24 497805.0 -86700.0 -0.43 -1.1839 -0.8992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B01 compound treatment 608126.0 53800.0 0.24 563271.0 -21300.0 -0.11 0.0958 0.3643 1972560 ChemDiv1_004599 CCC(=O)N1N=C(CC1c2ccccc2OC)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B02 compound treatment 641283.0 87000.0 0.39 617688.0 33100.0 0.16 0.3913 0.9263 1940813 ChemDiv1_004600 OCCCNC(=O)CCCSc1nc2sc3CCCCc3c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B03 compound treatment 689869.0 136000.0 0.61 668258.0 83700.0 0.41 0.7223 0.9828 1303907 ChemDiv1_004601 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B04 compound treatment 645591.0 91300.0 0.41 644488.0 59900.0 0.3 0.4989 0.9877 1527431 ChemDiv1_004602 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc(cs3)c4cc5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B05 compound treatment 713643.0 159000.0 0.71 696568.0 112000.0 0.55 0.8967 0.9923 1466106 ChemDiv1_004603 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B06 compound treatment 662003.0 108000.0 0.48 673111.0 88600.0 0.44 0.6511 0.9989 1972561 ChemDiv1_004604 O=C(CN1C(=O)c2ccccc2C1=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B07 compound treatment 723598.0 169000.0 0.76 700992.0 116000.0 0.58 0.9437 0.9909 1972562 ChemDiv1_004605 [O-][N+](=O)c1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B08 compound treatment 711732.0 157000.0 0.7 736266.0 152000.0 0.75 1.0297 0.9995 1634578 ChemDiv1_004606 COc1ccc(cc1)c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B09 compound treatment 741016.0 187000.0 0.84 733540.0 149000.0 0.74 1.1128 0.9981 1972563 ChemDiv1_004607 CCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OCC)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B10 compound treatment 708997.0 155000.0 0.69 707479.0 123000.0 0.61 0.9202 0.998 1606278 ChemDiv1_004608 OCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B11 compound treatment 736496.0 182000.0 0.82 769025.0 184000.0 0.91 1.2228 0.9984 1490483 ChemDiv1_004609 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B12 compound treatment 672402.0 118000.0 0.53 712589.0 128000.0 0.63 0.8223 0.9959 1634864 ChemDiv1_004610 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B13 compound treatment 721709.0 167000.0 0.75 745851.0 161000.0 0.8 1.0949 0.9995 1972564 ChemDiv1_004611 [O-][N+](=O)c1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B14 compound treatment 687578.0 133000.0 0.6 710270.0 126000.0 0.62 0.8622 0.9998 1940912 ChemDiv1_004612 C=CCn1c(SCC(=O)NCCCN2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B15 compound treatment 739426.0 185000.0 0.83 769177.0 185000.0 0.91 1.2326 0.9988 1972565 ChemDiv1_004613 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cc(Br)c(O)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B16 compound treatment 718956.0 165000.0 0.74 745614.0 161000.0 0.8 1.0853 0.9992 1972566 ChemDiv1_004614 Cc1nn(C(=O)c2sc3ccccc3c2Cl)c(C)c1Sc4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B17 compound treatment 741108.0 187000.0 0.84 771589.0 187000.0 0.93 1.2464 0.9987 1372303 ChemDiv1_004615 Brc1ccc(NC(=O)c2cc3ccccc3oc2=O)c(c1)C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B18 compound treatment 705245.0 151000.0 0.68 719084.0 135000.0 0.67 0.949 1.0 1500447 ChemDiv1_004616 CCN1C(=O)c2cccc3c(NC(=O)c4cc(nc5ccccc45)c6cccs6)ccc1c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B19 compound treatment 694598.0 140000.0 0.63 721450.0 137000.0 0.68 0.9236 0.9993 1610800 ChemDiv1_004617 O=C(Nc1nc2c(ccc3ccccc23)s1)c4cc(=O)c5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B20 compound treatment 689440.0 135000.0 0.6 699072.0 115000.0 0.57 0.8289 0.9995 1273021 ChemDiv1_004618 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B21 compound treatment 694628.0 140000.0 0.63 733133.0 149000.0 0.74 0.9646 0.9969 1972567 ChemDiv1_004619 COc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B22 compound treatment 674555.0 120000.0 0.54 686512.0 102000.0 0.51 0.7377 0.9995 1599333 ChemDiv1_004620 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B23 mock treatment 684520.0 130000.0 0.58 663008.0 78500.0 0.39 0.6869 0.9806 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 B24 mock treatment 539129.0 -15200.0 -0.07 213701.0 -371000.0 -1.84 -1.3471 -0.7328 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C01 compound treatment 611856.0 57500.0 0.26 556523.0 -28000.0 -0.14 0.0839 0.2869 1716490 ChemDiv1_004621 CN(C)c1nc(N)nc2ncn(C)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C02 compound treatment 659361.0 105000.0 0.47 683017.0 98500.0 0.49 0.6774 0.9998 1924398 ChemDiv1_004622 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)c4cc(ccc4Cl)C(=O)O)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C03 compound treatment 675358.0 121000.0 0.54 666933.0 82400.0 0.41 0.6717 0.9902 1339681 ChemDiv1_004623 COc1cc(ccc1OC(=O)N(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C04 compound treatment 688988.0 135000.0 0.6 676490.0 91900.0 0.46 0.7483 0.9904 1972568 ChemDiv1_004624 COc1cccc(c1)C(=O)/C=C\Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C05 compound treatment 672337.0 118000.0 0.53 676476.0 91900.0 0.46 0.6956 0.9973 1972569 ChemDiv1_004625 CCOC(=O)c1ccc(Nc2nc3nonc3nc2NOC(=O)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C06 compound treatment 632049.0 77700.0 0.35 661137.0 76600.0 0.38 0.5143 0.9991 1972570 ChemDiv1_004626 Cc1ccc(cc1)S(=O)(=O)N2C(=O)/C(=C/3\SC(=S)N(CC=C)C3=O)/c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C07 compound treatment 728301.0 174000.0 0.78 700529.0 116000.0 0.57 0.957 0.9888 1241444 ChemDiv1_004627 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C08 compound treatment 710469.0 156000.0 0.7 682038.0 97500.0 0.48 0.8357 0.9837 1972571 ChemDiv1_004628 CC(N)C(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C09 compound treatment 680402.0 126000.0 0.56 737588.0 153000.0 0.76 0.9352 0.9894 1972572 ChemDiv1_004629 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc(C)c([N+](=O)[O-])c4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C10 compound treatment 824927.0 271000.0 1.21 915075.0 331000.0 1.64 2.0143 0.989 1972573 ChemDiv1_004630 Fc1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C11 compound treatment 736277.0 182000.0 0.81 737183.0 153000.0 0.76 1.1106 0.9993 1714999 ChemDiv1_004631 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C12 compound treatment 655629.0 101000.0 0.45 693704.0 109000.0 0.54 0.703 0.9962 1972574 ChemDiv1_004632 COc1ccccc1NC(=O)CCCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C13 compound treatment 679554.0 125000.0 0.56 726563.0 142000.0 0.7 0.8939 0.9937 1930575 ChemDiv1_004633 Cc1ccccc1NC(=O)CSc2nnc(C)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C14 compound treatment 652274.0 98000.0 0.44 738622.0 154000.0 0.76 0.8497 0.9654 1972575 ChemDiv1_004634 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ccccc3C(=O)O)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C15 compound treatment 739749.0 185000.0 0.83 744591.0 160000.0 0.79 1.1475 0.9997 1972576 ChemDiv1_004635 CCOC(=O)Cn1nc(C)c2ccccc2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C16 compound treatment 699497.0 145000.0 0.65 726005.0 141000.0 0.7 0.955 0.9993 1972577 ChemDiv1_004636 O=C(CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4)NCCCN5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C17 compound treatment 720454.0 166000.0 0.74 735048.0 151000.0 0.75 1.053 1.0 1547279 ChemDiv1_004637 COc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C18 compound treatment 680930.0 127000.0 0.57 693669.0 109000.0 0.54 0.783 0.9997 1508911 ChemDiv1_004638 COC(=O)c1ccc(CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C19 compound treatment 694978.0 141000.0 0.63 739312.0 155000.0 0.77 0.9873 0.9952 1972578 ChemDiv1_004639 OC(=O)c1ccccc1c2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C20 compound treatment 679645.0 125000.0 0.56 698227.0 114000.0 0.56 0.7949 1.0 1524331 ChemDiv1_004640 COc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C21 compound treatment 684442.0 130000.0 0.58 704303.0 120000.0 0.59 0.8314 1.0 1946942 ChemDiv1_004641 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C\c3ccc(o3)c4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C22 compound treatment 656200.0 102000.0 0.46 649713.0 65200.0 0.32 0.5507 0.9857 1289875 ChemDiv1_004642 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CC(C)CC(C)C4)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C23 mock treatment 678607.0 124000.0 0.56 670939.0 86400.0 0.43 0.696 0.9916 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 C24 mock treatment 192355.0 -362000.0 -1.62 500024.0 -84500.0 -0.42 -1.4418 -0.8615 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D01 compound treatment 638013.0 83700.0 0.37 576288.0 -8260.0 -0.04 0.236 0.6262 1972579 ChemDiv1_004643 CC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D02 compound treatment 632932.0 78600.0 0.35 621752.0 37200.0 0.18 0.3791 0.9545 1972580 ChemDiv1_004644 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D03 compound treatment 693943.0 140000.0 0.62 688654.0 104000.0 0.52 0.8066 0.9954 1155069 ChemDiv1_004645 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D04 compound treatment 714976.0 161000.0 0.72 682844.0 98300.0 0.49 0.8528 0.982 1178343 ChemDiv1_004646 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5nc(C)sc5c4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D05 compound treatment 713058.0 159000.0 0.71 716138.0 132000.0 0.65 0.9634 0.9991 1164870 ChemDiv1_004647 CC(C)Sc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D06 compound treatment 686376.0 132000.0 0.59 702181.0 118000.0 0.58 0.83 1.0 1948716 ChemDiv1_004648 Fc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D07 compound treatment 739754.0 185000.0 0.83 725334.0 141000.0 0.7 1.0801 0.9963 1972581 ChemDiv1_004649 Clc1ccc(C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D08 compound treatment 740073.0 186000.0 0.83 718961.0 134000.0 0.67 1.0588 0.9939 1972582 ChemDiv1_004650 FC(F)(F)c1cccc(NC(=O)CSc2nnc3ccccn23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D09 compound treatment 721408.0 167000.0 0.75 769810.0 185000.0 0.92 1.1778 0.9948 1972583 ChemDiv1_004651 CCCCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OCC)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D10 compound treatment 708362.0 154000.0 0.69 735811.0 151000.0 0.75 1.0174 0.9991 1949763 ChemDiv1_004652 OC(=O)/C=C/c1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D11 compound treatment 754849.0 201000.0 0.9 820542.0 236000.0 1.17 1.4614 0.9915 1359872 ChemDiv1_004653 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D12 compound treatment 703153.0 149000.0 0.67 724266.0 140000.0 0.69 0.9605 0.9998 1395902 ChemDiv1_004654 C=CCn1c(SCC(=O)NCc2ccco2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D13 compound treatment 713554.0 159000.0 0.71 753987.0 169000.0 0.84 1.0975 0.9967 1972584 ChemDiv1_004655 Clc1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D14 compound treatment 735609.0 181000.0 0.81 679152.0 94600.0 0.47 0.9052 0.966 1972585 ChemDiv1_004656 OCCCNC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D15 compound treatment 751954.0 198000.0 0.88 790983.0 206000.0 1.02 1.3487 0.9974 1972586 ChemDiv1_004657 CCCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cc(Br)c(O)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D16 compound treatment 732598.0 178000.0 0.8 700961.0 116000.0 0.58 0.9721 0.9873 1972587 ChemDiv1_004658 CC(C)N(C(=O)CSc1nnc(COc2ccc(Cl)cc2Cl)o1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D17 compound treatment 775527.0 221000.0 0.99 754276.0 170000.0 0.84 1.2947 0.9967 1137778 ChemDiv1_004659 CCOC(=O)c1sc(cc1NC(=O)c2cc3ccccc3oc2=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D18 compound treatment 735362.0 181000.0 0.81 732192.0 148000.0 0.73 1.0902 0.9987 1257943 ChemDiv1_004660 CSc1nc2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D19 compound treatment 696061.0 142000.0 0.63 760393.0 176000.0 0.87 1.0646 0.9879 1559252 ChemDiv1_004661 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)c4cc(=O)c5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D20 compound treatment 745234.0 191000.0 0.85 744056.0 160000.0 0.79 1.163 0.9992 1278691 ChemDiv1_004662 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D21 compound treatment 733417.0 179000.0 0.8 753940.0 169000.0 0.84 1.1602 0.9997 1972588 ChemDiv1_004663 OC(=O)CCC(=O)N1N=C(CC1c2ccco2)c3c(O)nc4ccc(Br)cc4c3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D22 compound treatment 706603.0 152000.0 0.68 716729.0 132000.0 0.65 0.945 0.9998 1308274 ChemDiv1_004664 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D23 mock treatment 678235.0 124000.0 0.55 706758.0 122000.0 0.61 0.8203 0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 D24 mock treatment 523202.0 -31100.0 -0.14 515501.0 -69000.0 -0.34 -0.3404 -0.9216 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E01 compound treatment 602691.0 48400.0 0.22 573493.0 -11100.0 -0.05 0.1144 0.5121 1195375 ChemDiv1_004665 Cc1cc(C)n(n1)c2nc3nonc3nc2Nc4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E02 compound treatment 641594.0 87300.0 0.39 600256.0 15700.0 0.08 0.3313 0.8316 1972589 ChemDiv1_004666 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)c5cnc(nc5)c6ccc(cc6)N7C(=O)C8C9CC(C=C9)C8C7=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E03 compound treatment 730535.0 176000.0 0.79 717881.0 133000.0 0.66 1.0248 0.9961 1689319 ChemDiv1_004667 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(OC)c1OC(=O)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E04 compound treatment 667218.0 113000.0 0.51 645367.0 60800.0 0.3 0.5704 0.9695 1972590 ChemDiv1_004668 Clc1ccc(CN2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E05 compound treatment 2743426.0 2190000.0 9.8 3574683.0 2990000.0 14.81 17.4032 0.9799 1972591 ChemDiv1_004669 Fc1ccc(c2ccc(/C=C/3\Sc4ccccc4C3=O)o2)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E06 compound treatment 691303.0 137000.0 0.61 676082.0 91500.0 0.45 0.7542 0.989 1972592 ChemDiv1_004670 Cc1ccc(cc1)S(=O)(=O)N2C(=O)/C(=C/3\SC(=S)N(Cc4ccco4)C3=O)/c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E07 compound treatment 704272.0 150000.0 0.67 725662.0 141000.0 0.7 0.9689 0.9998 1972593 ChemDiv1_004671 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E08 compound treatment 714199.0 160000.0 0.72 725568.0 141000.0 0.7 1.0 0.9999 1426744 ChemDiv1_004672 Fc1ccc(Cc2cnc(NC(=O)c3csc4CCCCc34)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E09 compound treatment 679477.0 125000.0 0.56 723696.0 139000.0 0.69 0.8836 0.9947 1972594 ChemDiv1_004673 [O-][N+](=O)c1cc(C(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)c(Cl)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E10 compound treatment 1044121.0 490000.0 2.19 1107805.0 523000.0 2.59 3.3833 0.9965 1951684 ChemDiv1_004674 Oc1ccc(Cl)cc1NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E11 compound treatment 700035.0 146000.0 0.65 756850.0 172000.0 0.85 1.0648 0.9912 1484799 ChemDiv1_004675 OCCNC(=O)Cc1n[nH]c(=O)c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E12 compound treatment 740260.0 186000.0 0.83 742424.0 158000.0 0.78 1.1416 0.9995 1972595 ChemDiv1_004676 OC(=O)c1ccc(NC(=O)CCCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E13 compound treatment 720831.0 167000.0 0.75 735687.0 151000.0 0.75 1.0565 1.0 1972596 ChemDiv1_004677 Cc1ccc(NC(=O)CSc2nnc(C)c3ccccc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E14 compound treatment 744636.0 190000.0 0.85 750913.0 166000.0 0.82 1.1852 0.9999 1972597 ChemDiv1_004678 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3nnc(CC(C)C)s3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E15 compound treatment 751978.0 198000.0 0.88 745067.0 161000.0 0.8 1.1879 0.9986 1284873 ChemDiv1_004679 CC(=O)Nc1ccc(Oc2nnc(c3ccccc3)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E16 compound treatment 738035.0 184000.0 0.82 722797.0 138000.0 0.68 1.0658 0.9959 1941241 ChemDiv1_004680 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccccn6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E17 compound treatment 726880.0 173000.0 0.77 721208.0 137000.0 0.68 1.0249 0.9978 1458322 ChemDiv1_004681 COc1ccc(cc1)c2nnc(OC)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E18 compound treatment 709570.0 155000.0 0.69 717331.0 133000.0 0.66 0.9565 0.9996 1945419 ChemDiv1_004682 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E19 compound treatment 727368.0 173000.0 0.77 743494.0 159000.0 0.79 1.1045 1.0 1972598 ChemDiv1_004683 COc1cc(ccc1c2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)o2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E20 compound treatment 736249.0 182000.0 0.81 710480.0 126000.0 0.62 1.017 0.9913 1297436 ChemDiv1_004684 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E21 compound treatment 730618.0 176000.0 0.79 736699.0 152000.0 0.75 1.091 0.9997 1946487 ChemDiv1_004685 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(Br)o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E22 compound treatment 674211.0 120000.0 0.54 702830.0 118000.0 0.59 0.7938 0.999 1315776 ChemDiv1_004686 CCOc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CC(C)CC(C)C4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E23 mock treatment 699300.0 145000.0 0.65 711129.0 127000.0 0.63 0.9023 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 E24 mock treatment 237517.0 -317000.0 -1.42 500297.0 -84300.0 -0.42 -1.2979 -0.878 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F01 compound treatment 648638.0 94300.0 0.42 601607.0 17100.0 0.08 0.3583 0.8321 1972599 ChemDiv1_004687 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F02 compound treatment 685918.0 132000.0 0.59 641671.0 57100.0 0.28 0.6166 0.9436 1946341 ChemDiv1_004688 COc1ccc(cc1)C(=O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F03 compound treatment 700137.0 146000.0 0.65 686482.0 102000.0 0.5 0.8186 0.992 1280694 ChemDiv1_004689 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F04 compound treatment 681811.0 127000.0 0.57 676078.0 91500.0 0.45 0.7242 0.9935 1972600 ChemDiv1_004690 [O-][N+](=O)c1csc(c1)c2csc(NC(=O)c3cc(nc4ccccc34)c5cccs5)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F05 compound treatment 706748.0 152000.0 0.68 718527.0 134000.0 0.66 0.9518 0.9999 1782841 ChemDiv1_004691 CN1CCN(CC1)c2nc3n(C)c(=O)[nH]c(=O)c3n2CC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F06 compound treatment 701532.0 147000.0 0.66 707199.0 123000.0 0.61 0.8956 0.9992 1972601 ChemDiv1_004692 Fc1ccc(cc1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F07 compound treatment 735373.0 181000.0 0.81 747528.0 163000.0 0.81 1.144 1.0 1160082 ChemDiv1_004693 CCOC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OCC)cc3)c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F08 compound treatment 724762.0 170000.0 0.76 750551.0 166000.0 0.82 1.121 0.9993 1972602 ChemDiv1_004694 Cc1cc2nnc(SCC(=O)Nc3ccc(F)cc3)n2c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F09 compound treatment 743225.0 189000.0 0.85 774431.0 190000.0 0.94 1.2631 0.9986 1972603 ChemDiv1_004695 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OCc3ccccc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F10 compound treatment 699766.0 145000.0 0.65 705926.0 121000.0 0.6 0.8855 0.9992 1940853 ChemDiv1_004696 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F11 compound treatment 762683.0 208000.0 0.93 791671.0 207000.0 1.03 1.385 0.9989 1526154 ChemDiv1_004697 COc1ccc(cc1)C(=O)c2sc3nc(N)c(C#N)c(c4ccc(OC)cc4)c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F12 compound treatment 754312.0 200000.0 0.9 724011.0 139000.0 0.69 1.1215 0.9918 1697403 ChemDiv1_004698 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F13 compound treatment 747747.0 193000.0 0.87 780188.0 196000.0 0.97 1.2975 0.9984 1223221 ChemDiv1_004699 CCOC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OC)c(OC)c3)c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F14 compound treatment 719154.0 165000.0 0.74 690659.0 106000.0 0.53 0.8934 0.9862 1712761 ChemDiv1_004700 OCCNC(=O)c1ccc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F15 compound treatment 731365.0 177000.0 0.79 715019.0 130000.0 0.65 1.0174 0.9949 1972604 ChemDiv1_004701 CCOc1ccc(cc1)C2C(C(=O)OC)C(=O)NC(=C2C#N)SCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F16 compound treatment 729700.0 175000.0 0.79 737662.0 153000.0 0.76 1.0915 0.9999 1972605 ChemDiv1_004702 CCNc1nc(NCC)n2c(SCC(=O)c3ccc(cc3)C(C)C)nnc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F17 compound treatment 731194.0 177000.0 0.79 733199.0 149000.0 0.74 1.0806 0.9993 1972606 ChemDiv1_004703 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3nc(cs3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F18 compound treatment 689815.0 135000.0 0.61 719632.0 135000.0 0.67 0.9021 0.9988 1972607 ChemDiv1_004704 FC(F)(F)C(=O)c1sc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)nc1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F19 compound treatment 732932.0 179000.0 0.8 720993.0 136000.0 0.68 1.0433 0.9965 1572199 ChemDiv1_004705 CCOC(=O)c1sc(NC(=O)c2cc(=O)c3ccccc3o2)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F20 compound treatment 708024.0 154000.0 0.69 737319.0 153000.0 0.76 1.0216 0.9989 1656582 ChemDiv1_004706 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F21 compound treatment 763794.0 209000.0 0.94 753940.0 169000.0 0.84 1.2564 0.9985 1251575 ChemDiv1_004707 CCN(CC)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F22 compound treatment 685780.0 131000.0 0.59 716399.0 132000.0 0.65 0.878 0.9986 1330313 ChemDiv1_004708 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F23 mock treatment 680368.0 126000.0 0.56 710140.0 126000.0 0.62 0.8389 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 F24 mock treatment 518545.0 -35800.0 -0.16 510483.0 -74100.0 -0.37 -0.3727 -0.9309 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G01 compound treatment 641786.0 87500.0 0.39 570995.0 -13600.0 -0.07 0.2294 0.5774 1511107 ChemDiv1_004709 Cc1cccc(Nc2nc3nonc3nc2N4CCCCC4)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G02 compound treatment 625112.0 70800.0 0.32 613474.0 28900.0 0.14 0.3254 0.9356 1972608 ChemDiv1_004710 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc(cc3)c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G03 compound treatment 877946.0 324000.0 1.45 902130.0 318000.0 1.57 2.1368 0.9992 1972609 ChemDiv1_004711 COc1cc(/C=C/2\S/C(=N\c3ccc4OCOc4c3)/N(C2=O)c5ccc6OCOc6c5)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G04 compound treatment 655883.0 102000.0 0.45 646058.0 61500.0 0.3 0.5369 0.9811 1972610 ChemDiv1_004712 [O-][N+](=O)c1ccc2NC(=O)/C(=C/3\SC(=S)N(Cc4ccc(Cl)cc4)C3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G05 compound treatment 1058026.0 504000.0 2.25 1009426.0 425000.0 2.1 3.0827 0.9994 1431118 ChemDiv1_004713 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(Br)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G06 compound treatment 688983.0 135000.0 0.6 680191.0 95600.0 0.47 0.7613 0.9929 1320036 ChemDiv1_004714 CC(=O)N(Cc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G07 compound treatment 696051.0 142000.0 0.63 718661.0 134000.0 0.66 0.9184 0.9997 1972611 ChemDiv1_004715 [O-][N+](=O)c1ccc(/C=C/C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G08 compound treatment 702456.0 148000.0 0.66 709315.0 125000.0 0.62 0.9059 0.9994 1972612 ChemDiv1_004716 CCc1nnc(/N=C\2/S\C(=C/c3ccccc3F)\C(=O)N2CC=C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G09 compound treatment 720325.0 166000.0 0.74 724001.0 139000.0 0.69 1.0139 0.9993 1972613 ChemDiv1_004717 O=C(Nn1c(nc2ccccc2c1=O)c3cccs3)c4cc5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G10 compound treatment 909400.0 355000.0 1.59 902526.0 318000.0 1.58 2.2378 1.0 1928130 ChemDiv1_004718 OC(=O)c1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G11 compound treatment 690126.0 136000.0 0.61 711270.0 127000.0 0.63 0.8737 0.9999 1557433 ChemDiv1_004719 O=C(CSc1nc2ccccc2o1)NCc3n[nH]c(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G12 compound treatment 722223.0 168000.0 0.75 728879.0 144000.0 0.71 1.037 0.9997 1928020 ChemDiv1_004720 Brc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NCCCN3CCOCC3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G13 compound treatment 720545.0 166000.0 0.74 742996.0 158000.0 0.78 1.0812 0.9996 1972614 ChemDiv1_004721 Cc1ccc(C)c(NC(=O)CSc2nnc(C)c3ccccc23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G14 compound treatment 915877.0 362000.0 1.62 1146360.0 562000.0 2.78 3.1124 0.9667 1972615 ChemDiv1_004722 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ncc(Cc4ccccc4Cl)s3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G15 compound treatment 751808.0 197000.0 0.88 756874.0 172000.0 0.85 1.2287 0.9998 1463821 ChemDiv1_004723 COc1ccc(cc1)c2nnc(N3CCOCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G16 compound treatment 726656.0 172000.0 0.77 715241.0 131000.0 0.65 1.0033 0.9962 1941131 ChemDiv1_004724 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCn6ccnc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G17 compound treatment 746867.0 193000.0 0.86 741209.0 157000.0 0.78 1.1582 0.9986 1486653 ChemDiv1_004725 COc1ccc(cc1)c2nnc(N3CCCCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G18 compound treatment 703948.0 150000.0 0.67 723094.0 139000.0 0.69 0.9589 0.9999 1945357 ChemDiv1_004726 CCOC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G19 compound treatment 738939.0 185000.0 0.83 795024.0 210000.0 1.04 1.3216 0.9934 1927371 ChemDiv1_004727 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc(OC)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G20 compound treatment 680920.0 127000.0 0.57 649660.0 65100.0 0.32 0.6288 0.9643 1873276 ChemDiv1_004728 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)OC)C#N)c2ccccc2OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G21 compound treatment 745142.0 191000.0 0.85 763729.0 179000.0 0.89 1.2316 0.9998 1946662 ChemDiv1_004729 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(o3)c4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G22 compound treatment 653448.0 99100.0 0.44 700845.0 116000.0 0.58 0.7211 0.9917 1674741 ChemDiv1_004730 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Cl)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G23 mock treatment 674452.0 120000.0 0.54 693241.0 109000.0 0.54 0.761 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 G24 mock treatment 493597.0 -60700.0 -0.27 490592.0 -94000.0 -0.47 -0.5213 -0.9672 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H01 compound treatment 620022.0 65700.0 0.29 593510.0 8960.0 0.04 0.2394 0.8047 1972616 ChemDiv1_004731 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H02 compound treatment 682312.0 128000.0 0.57 640682.0 56100.0 0.28 0.6018 0.9449 1941000 ChemDiv1_004732 Fc1ccc(cc1)C(=O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H03 compound treatment 688648.0 134000.0 0.6 640487.0 55900.0 0.28 0.6211 0.9381 1191359 ChemDiv1_004733 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H04 compound treatment 689702.0 135000.0 0.61 674240.0 89700.0 0.44 0.7427 0.9884 1941214 ChemDiv1_004734 OCCCNC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H05 compound treatment 689347.0 135000.0 0.6 700834.0 116000.0 0.58 0.8347 0.9997 1782845 ChemDiv1_004735 CN1CCN(CC1)c2nc3n(C)c(=O)[nH]c(=O)c3n2CC(O)COc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H06 compound treatment 681926.0 128000.0 0.57 705132.0 121000.0 0.6 0.8263 0.9997 1972617 ChemDiv1_004736 COc1ccc(cc1)C(=O)CSc2nnc(c3ccc4OCOc4c3)n2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H07 compound treatment 716170.0 162000.0 0.72 751404.0 167000.0 0.83 1.0968 0.9978 1661403 ChemDiv1_004737 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H08 compound treatment 719997.0 166000.0 0.74 729773.0 145000.0 0.72 1.0331 0.9999 1972618 ChemDiv1_004738 Brc1ccc(NC(=O)CSc2nnc3ccccn23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H09 compound treatment 727966.0 174000.0 0.78 765371.0 181000.0 0.9 1.183 0.9975 1972619 ChemDiv1_004739 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccccc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H10 compound treatment 685356.0 131000.0 0.59 742281.0 158000.0 0.78 0.9673 0.99 1949850 ChemDiv1_004740 O=C(CN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(CCN5C(=O)C6C7CC(C=C7)C6C5=O)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H11 compound treatment 1010748.0 456000.0 2.04 1141682.0 557000.0 2.76 3.3963 0.989 1288245 ChemDiv1_004741 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H12 compound treatment 707453.0 153000.0 0.69 711732.0 127000.0 0.63 0.9302 0.9991 1527352 ChemDiv1_004742 OCCN(CCO)C(=O)CSc1nc2sc3CCCc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H13 compound treatment 699680.0 145000.0 0.65 745367.0 161000.0 0.8 1.0234 0.995 1716831 ChemDiv1_004743 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)N)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H14 compound treatment 709660.0 155000.0 0.7 721910.0 137000.0 0.68 0.9729 0.9999 1725986 ChemDiv1_004744 C=CCn1c(SCC(=O)N2CCCCC2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H15 compound treatment 768705.0 214000.0 0.96 771984.0 187000.0 0.93 1.3351 0.9999 1432560 ChemDiv1_004745 CC1CCc2nc(NC(=O)c3cc(=O)c4ccccc4o3)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H16 compound treatment 713918.0 160000.0 0.71 732793.0 148000.0 0.73 1.0245 0.9999 1972620 ChemDiv1_004746 CCNc1nc(NCC)n2c(SCC(=O)c3ccc(cc3)C(C)(C)C)nnc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H17 compound treatment 763541.0 209000.0 0.94 752400.0 168000.0 0.83 1.2502 0.9982 1972621 ChemDiv1_004747 Oc1ccc(NC(=O)c2cc3cc(ccc3s2)[N+](=O)[O-])cc1c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H18 compound treatment 713517.0 159000.0 0.71 761354.0 177000.0 0.88 1.1232 0.9948 1563078 ChemDiv1_004748 COc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H19 compound treatment 727620.0 173000.0 0.78 739720.0 155000.0 0.77 1.0921 1.0 1470888 ChemDiv1_004749 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)c4cc(=O)c5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H20 compound treatment 704333.0 150000.0 0.67 722617.0 138000.0 0.68 0.9585 1.0 1682202 ChemDiv1_004750 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H21 compound treatment 779808.0 225000.0 1.01 763716.0 179000.0 0.89 1.3413 0.9979 1599263 ChemDiv1_004751 CCN(CC)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H22 compound treatment 706915.0 153000.0 0.68 731892.0 147000.0 0.73 0.9991 0.9995 1417710 ChemDiv1_004752 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H23 mock treatment 660372.0 106000.0 0.47 707634.0 123000.0 0.61 0.7668 0.9923 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 H24 mock treatment 507217.0 -47100.0 -0.21 519145.0 -65400.0 -0.32 -0.3782 -0.9784 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I01 compound treatment 615254.0 60900.0 0.27 560952.0 -23600.0 -0.12 0.1102 0.3714 1694352 ChemDiv1_004753 Cc1ccccc1Nc2nc3nonc3nc2N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I02 compound treatment 652812.0 98500.0 0.44 610740.0 26200.0 0.13 0.4035 0.878 1946250 ChemDiv1_004754 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4ccc(cc4)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I03 compound treatment 712715.0 158000.0 0.71 669868.0 85300.0 0.42 0.8002 0.9694 1972622 ChemDiv1_004755 Cc1ccc2c(nc3sc(=Cc4cc([N+](=O)[O-])c(cc4N5CCOCC5)N6CCOCC6)c(=O)n32)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I04 compound treatment 682486.0 128000.0 0.57 665171.0 80600.0 0.4 0.6881 0.9843 1972623 ChemDiv1_004756 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)Nc4ccc(Cl)cc34)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I05 compound treatment 1004529.0 450000.0 2.02 845709.0 261000.0 1.29 2.3398 0.977 1942668 ChemDiv1_004757 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc3sc(=O)oc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I06 compound treatment 675013.0 121000.0 0.54 634080.0 49500.0 0.25 0.5555 0.9362 1308050 ChemDiv1_004758 c1c(nc2c3ccccc3ccn12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I07 compound treatment 740839.0 187000.0 0.83 706646.0 122000.0 0.6 1.0181 0.9875 1554519 ChemDiv1_004759 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I08 compound treatment 725596.0 171000.0 0.77 692067.0 108000.0 0.53 0.9188 0.9842 1942602 ChemDiv1_004760 Brc1ccccc1C(=O)NN2C(=O)/C(=C\3/C(=O)Nc4ccccc34)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I09 compound treatment 729480.0 175000.0 0.78 694048.0 110000.0 0.54 0.938 0.9838 1972624 ChemDiv1_004761 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I10 compound treatment 1196680.0 642000.0 2.88 1176210.0 592000.0 2.93 4.1058 1.0 1972625 ChemDiv1_004762 O=C(CCN1C(=O)/C(=C\c2cccs2)/SC1=S)Nc3ccccn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I11 compound treatment 681348.0 127000.0 0.57 732120.0 148000.0 0.73 0.919 0.9923 1328429 ChemDiv1_004763 Cc1nnc(Nc2ccccc2O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I12 compound treatment 725661.0 171000.0 0.77 725481.0 141000.0 0.7 1.036 0.9989 1972626 ChemDiv1_004764 CC(=O)N1C(=O)/C(=C/2\SC(=NC2=O)Nc3ccc(Br)cc3)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I13 compound treatment 723989.0 170000.0 0.76 710380.0 126000.0 0.62 0.9778 0.9952 1972627 ChemDiv1_004765 Cc1nnc(SCC(=O)Nc2ccc(Cl)c(Cl)c2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I14 compound treatment 755126.0 201000.0 0.9 762757.0 178000.0 0.88 1.2598 1.0 1972628 ChemDiv1_004766 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3nc4ccccc4s3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I15 compound treatment 778072.0 224000.0 1.0 727149.0 143000.0 0.71 1.2077 0.9854 1179090 ChemDiv1_004767 CCCOC(=O)c1ccc(cc1)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I16 compound treatment 733724.0 179000.0 0.8 689140.0 105000.0 0.52 0.9342 0.9775 1948540 ChemDiv1_004768 Cc1sc2nc(SCC(=O)NCCCN3CCOCC3)n(c4ccccc4)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I17 compound treatment 754866.0 201000.0 0.9 729938.0 145000.0 0.72 1.1441 0.994 1239167 ChemDiv1_004769 COc1ccc(cc1)c2nnc(NCc3nc4ccccc4[nH]3)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I18 compound treatment 693988.0 140000.0 0.63 683404.0 98900.0 0.49 0.7884 0.9927 1945961 ChemDiv1_004770 CCOC(=O)CSc1nnc(c2ccncc2)n1c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I19 compound treatment 733986.0 180000.0 0.8 713448.0 129000.0 0.64 1.0202 0.9935 1972629 ChemDiv1_004771 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)cc(OC)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I20 compound treatment 707717.0 153000.0 0.69 672984.0 88400.0 0.44 0.7953 0.9764 1873278 ChemDiv1_004772 CCOC(=O)CSC1=C(C#N)C(C(C(=O)OCC)C(=O)N1)c2ccccc2OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I21 compound treatment 744814.0 190000.0 0.85 740278.0 156000.0 0.77 1.1485 0.9988 1947065 ChemDiv1_004773 COc1cc(ccc1c2ccc(/C=C\3/C(=C(C#N)c4nc(N)c(C#N)c(C)c34)C)o2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I22 compound treatment 684282.0 130000.0 0.58 691714.0 107000.0 0.53 0.7867 0.999 1230321 ChemDiv1_004774 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Br)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I23 mock treatment 690585.0 136000.0 0.61 700834.0 116000.0 0.58 0.8386 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 I24 mock treatment 216988.0 -337000.0 -1.51 503134.0 -81400.0 -0.4 -1.3529 -0.8656 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J01 compound treatment 624190.0 69900.0 0.31 585763.0 1220.0 0.01 0.2254 0.7206 1273795 ChemDiv1_004775 NS(=O)(=O)c1ccc2nc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J02 compound treatment 659582.0 105000.0 0.47 627727.0 43200.0 0.21 0.4844 0.9362 1972630 ChemDiv1_004776 Fc1ccc(cc1)c2csc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J03 compound treatment 692327.0 138000.0 0.62 683899.0 99400.0 0.49 0.7848 0.9937 1519314 ChemDiv1_004777 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J04 compound treatment 692693.0 138000.0 0.62 654757.0 70200.0 0.35 0.6839 0.9628 1972631 ChemDiv1_004778 OCCCNC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J05 compound treatment 675978.0 122000.0 0.54 693012.0 108000.0 0.54 0.765 1.0 1940699 ChemDiv1_004779 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J06 compound treatment 673393.0 119000.0 0.53 693824.0 109000.0 0.54 0.7597 1.0 1156589 ChemDiv1_004780 C=CCSc1nc2ccccc2n1C(=O)CN3C(=O)c4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J07 compound treatment 798036.0 244000.0 1.09 760429.0 176000.0 0.87 1.3875 0.9938 1400349 ChemDiv1_004781 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J08 compound treatment 703958.0 150000.0 0.67 715087.0 131000.0 0.65 0.9309 0.9998 1972632 ChemDiv1_004782 Cc1ccc(cc1C)c2nnc(SC(F)F)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J09 compound treatment 725317.0 171000.0 0.77 752071.0 168000.0 0.83 1.1281 0.9992 1972633 ChemDiv1_004783 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(C)cc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J10 compound treatment 690443.0 136000.0 0.61 735195.0 151000.0 0.75 0.9586 0.9949 1478057 ChemDiv1_004784 C=CCn1c(SCC(=O)NCc2cccnc2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J11 compound treatment 735049.0 181000.0 0.81 726043.0 141000.0 0.7 1.0677 0.9974 1972634 ChemDiv1_004785 CCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OC)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J12 compound treatment 681233.0 127000.0 0.57 708524.0 124000.0 0.61 0.836 0.9992 1210944 ChemDiv1_004786 Cc1sc2nc(SCC(=O)N3CCN(CCO)CC3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J13 compound treatment 829953.0 276000.0 1.23 791107.0 207000.0 1.02 1.596 0.9957 1217980 ChemDiv1_004787 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J14 compound treatment 699837.0 146000.0 0.65 737200.0 153000.0 0.76 0.9953 0.9972 1540046 ChemDiv1_004788 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J15 compound treatment 726683.0 172000.0 0.77 725012.0 140000.0 0.7 1.0376 0.9987 1687347 ChemDiv1_004789 Brc1ccc(cc1)c2csc(NC(=O)c3cc(=O)c4ccccc4o3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J16 compound treatment 717859.0 164000.0 0.73 714536.0 130000.0 0.64 0.973 0.998 1972635 ChemDiv1_004790 CCNc1nc(NCC)n2c(SCC(=O)N(C(C)C)c3ccccc3)nnc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J17 compound treatment 734092.0 180000.0 0.8 733428.0 149000.0 0.74 1.0905 0.9991 1972636 ChemDiv1_004791 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3ccc(Cl)cc3C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J18 compound treatment 723653.0 169000.0 0.76 721256.0 137000.0 0.68 1.0149 0.9984 1246111 ChemDiv1_004792 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J19 compound treatment 721747.0 167000.0 0.75 735704.0 151000.0 0.75 1.0594 1.0 1642814 ChemDiv1_004793 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3CCC(C)Cc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J20 compound treatment 718886.0 165000.0 0.74 719229.0 135000.0 0.67 0.9927 0.9988 1692422 ChemDiv1_004794 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J21 compound treatment 714335.0 160000.0 0.72 764467.0 180000.0 0.89 1.1367 0.9941 1163233 ChemDiv1_004795 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J22 compound treatment 685726.0 131000.0 0.59 692061.0 108000.0 0.53 0.7925 0.9988 1221586 ChemDiv1_004796 COc1ccc(cc1)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J23 mock treatment 686751.0 132000.0 0.59 709398.0 125000.0 0.62 0.8565 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 J24 mock treatment 505186.0 -49100.0 -0.22 504034.0 -80500.0 -0.4 -0.4376 -0.9607 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K01 compound treatment 625395.0 71100.0 0.32 555923.0 -28600.0 -0.14 0.1247 0.358 1421740 ChemDiv1_004797 CC(C)Nc1nc2nonc2nc1Nc3cccc(C)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K02 compound treatment 649306.0 95000.0 0.43 591668.0 7120.0 0.04 0.3256 0.7631 1972637 ChemDiv1_004798 CCN1C(=O)c2ccc(cc2C1=O)c3ccc(/C=C/4\C(=NN(C4=O)c5ccc(cc5)C(=O)O)C)o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K03 compound treatment 768822.0 215000.0 0.96 684899.0 100000.0 0.5 1.0305 0.953 1509448 ChemDiv1_004799 COc1cc(ccc1OC(=O)N(C)C)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K04 compound treatment 676234.0 122000.0 0.55 648045.0 63500.0 0.31 0.6083 0.9657 1972638 ChemDiv1_004800 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)Nc4ccc(cc34)[N+](=O)[O-])/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K05 compound treatment 712763.0 158000.0 0.71 663971.0 79400.0 0.39 0.7797 0.9614 1972639 ChemDiv1_004801 Cc1ccc(Nc2nc3nonc3nc2Nc4ccccc4OC(=O)c5ccccc5)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K06 compound treatment 680042.0 126000.0 0.56 659275.0 74700.0 0.37 0.6597 0.9794 1426065 ChemDiv1_004802 Clc1ccc(cc1)c2cn3ccc4ccccc4c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K07 compound treatment 709268.0 155000.0 0.69 668484.0 83900.0 0.42 0.7845 0.9701 1353631 ChemDiv1_004803 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K08 compound treatment 691060.0 137000.0 0.61 684340.0 99800.0 0.49 0.7824 0.9944 1922566 ChemDiv1_004804 CN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cccc(Br)c3)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K09 compound treatment 735043.0 181000.0 0.81 727412.0 143000.0 0.71 1.0725 0.9978 1972640 ChemDiv1_004805 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K10 compound treatment 860477.0 306000.0 1.37 830959.0 246000.0 1.22 1.8322 0.9983 1923919 ChemDiv1_004806 O=C(CCN1C(=O)/C(=C/c2cccs2)/SC1=S)NC3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K11 compound treatment 708102.0 154000.0 0.69 711633.0 127000.0 0.63 0.9319 0.999 1672206 ChemDiv1_004807 Cc1nnc(Nc2ccc(cc2)C(=O)NCCO)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K12 compound treatment 701211.0 147000.0 0.66 679214.0 94700.0 0.47 0.7965 0.9863 1928039 ChemDiv1_004808 CCOc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K13 compound treatment 711592.0 157000.0 0.7 701695.0 117000.0 0.58 0.9082 0.9954 1972641 ChemDiv1_004809 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K14 compound treatment 712037.0 158000.0 0.71 702247.0 118000.0 0.58 0.9115 0.9955 1940864 ChemDiv1_004810 CCOC(=O)CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K15 compound treatment 729232.0 175000.0 0.78 712152.0 128000.0 0.63 1.0006 0.9944 1972642 ChemDiv1_004811 CCCCOC(=O)c1ccc(cc1)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K16 compound treatment 726782.0 172000.0 0.77 681536.0 97000.0 0.48 0.8856 0.974 1941229 ChemDiv1_004812 Cc1sc2nc(SCC(=O)NCCO)n(c3ccccc3)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K17 compound treatment 749344.0 195000.0 0.87 698363.0 114000.0 0.56 1.016 0.9776 1972643 ChemDiv1_004813 COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K18 compound treatment 713037.0 159000.0 0.71 703368.0 119000.0 0.59 0.9186 0.9956 1972644 ChemDiv1_004814 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCCN4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K19 compound treatment 743723.0 189000.0 0.85 697500.0 113000.0 0.56 0.9952 0.9797 1972645 ChemDiv1_004815 OC(=O)c1ccccc1c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc(F)cc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K20 compound treatment 721111.0 167000.0 0.75 676201.0 91700.0 0.45 0.849 0.9716 1452858 ChemDiv1_004816 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4cccc(F)c4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K21 compound treatment 719267.0 165000.0 0.74 724174.0 140000.0 0.69 1.0112 0.9995 1946730 ChemDiv1_004817 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccc(o3)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K22 compound treatment 697344.0 143000.0 0.64 664593.0 80000.0 0.4 0.7331 0.9735 1413062 ChemDiv1_004818 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K23 mock treatment 669677.0 115000.0 0.52 689007.0 104000.0 0.52 0.731 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 K24 mock treatment 314212.0 -240000.0 -1.07 504788.0 -79800.0 -0.4 -1.0394 -0.9077 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L01 compound treatment 620696.0 66400.0 0.3 573961.0 -10600.0 -0.05 0.173 0.5734 1787254 ChemDiv1_004819 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3cc(nc4ccccc34)c5ccccc5)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L02 compound treatment 666802.0 112000.0 0.5 626684.0 42100.0 0.21 0.5036 0.924 1972646 ChemDiv1_004820 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)cc2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L03 compound treatment 701981.0 148000.0 0.66 673435.0 88900.0 0.44 0.7787 0.9805 1612624 ChemDiv1_004821 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L04 compound treatment 679501.0 125000.0 0.56 657255.0 72700.0 0.36 0.6509 0.9772 1948876 ChemDiv1_004822 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L05 compound treatment 680762.0 126000.0 0.57 662544.0 78000.0 0.39 0.6734 0.9827 1943902 ChemDiv1_004823 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L06 compound treatment 657864.0 104000.0 0.46 648307.0 63800.0 0.32 0.5511 0.9825 1509679 ChemDiv1_004824 Cc1ccc(Sc2c(nc3ccccn23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L07 compound treatment 723170.0 169000.0 0.76 722190.0 138000.0 0.68 1.0166 0.9987 1252445 ChemDiv1_004825 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L08 compound treatment 692131.0 138000.0 0.62 700915.0 116000.0 0.58 0.8438 0.9994 1275320 ChemDiv1_004826 Cc1ccc(cc1C)c2nnc(n3nnc4ccccc34)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L09 compound treatment 701297.0 147000.0 0.66 741517.0 157000.0 0.78 1.0151 0.9965 1972647 ChemDiv1_004827 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(OC)cc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L10 compound treatment 672065.0 118000.0 0.53 700920.0 116000.0 0.58 0.7803 0.999 1972648 ChemDiv1_004828 Cc1sc2nc(SCC(=O)NCc3ccco3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L11 compound treatment 712389.0 158000.0 0.71 733255.0 149000.0 0.74 1.0212 0.9998 1972649 ChemDiv1_004829 CCCCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(OC)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L12 compound treatment 729354.0 175000.0 0.78 726919.0 142000.0 0.71 1.0527 0.9986 1940960 ChemDiv1_004830 O=C(CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6ccco6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L13 compound treatment 723349.0 169000.0 0.76 767446.0 183000.0 0.91 1.1757 0.996 1383626 ChemDiv1_004831 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccccc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L14 compound treatment 687623.0 133000.0 0.6 665391.0 80800.0 0.4 0.7051 0.9812 1212649 ChemDiv1_004832 Cc1sc2nc(SCc3ccc(cc3)C(=O)NCCO)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L15 compound treatment 726000.0 172000.0 0.77 745856.0 161000.0 0.8 1.1085 0.9998 1972650 ChemDiv1_004833 Brc1ccc(s1)c2csc(NC(=O)c3cc(=O)c4ccccc4o3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L16 compound treatment 709278.0 155000.0 0.69 712116.0 128000.0 0.63 0.9373 0.9989 1647746 ChemDiv1_004834 CCc1nnc2sc(nn12)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L17 compound treatment 733562.0 179000.0 0.8 735065.0 151000.0 0.75 1.0946 0.9993 1972651 ChemDiv1_004835 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L18 compound treatment 654202.0 99900.0 0.45 714595.0 130000.0 0.64 0.7717 0.9841 1972652 ChemDiv1_004836 OC(=O)CCCC(=O)N1N=C(CC1c2ccc(Cl)cc2)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L19 compound treatment 621180.0 66900.0 0.3 720546.0 136000.0 0.67 0.688 0.9333 1939962 ChemDiv1_004837 CC(=O)Nc1ccc(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L20 compound treatment 677992.0 124000.0 0.55 709461.0 125000.0 0.62 0.829 0.9985 1217188 ChemDiv1_004838 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L21 compound treatment 647710.0 93400.0 0.42 744717.0 160000.0 0.79 0.8567 0.9552 1678372 ChemDiv1_004839 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L22 compound treatment 687226.0 133000.0 0.59 692270.0 108000.0 0.53 0.798 0.9985 1785229 ChemDiv1_004840 CCOc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccc(C)cc4)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L23 mock treatment 660101.0 106000.0 0.47 698647.0 114000.0 0.57 0.7345 0.9961 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 L24 mock treatment 501197.0 -53100.0 -0.24 514011.0 -70500.0 -0.35 -0.4152 -0.9824 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M01 compound treatment 643714.0 89400.0 0.4 566566.0 -18000.0 -0.09 0.22 0.5366 1430945 ChemDiv1_004841 OCCNc1nc2nonc2nc1Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M02 compound treatment 670734.0 116000.0 0.52 593751.0 9200.0 0.05 0.4007 0.766 1702630 ChemDiv1_004842 COCc1cc(C)nc2sc(C(=O)c3ccccc3)c(NC(=O)c4ccccc4)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M03 compound treatment 759479.0 205000.0 0.92 692538.0 108000.0 0.53 1.0277 0.9669 1972653 ChemDiv1_004843 CC(=O)/N=C\1/NC(=O)/C(=C/c2ccc(o2)c3ccc(F)cc3F)/S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M04 compound treatment 669254.0 115000.0 0.51 634443.0 49900.0 0.25 0.5386 0.9436 1972654 ChemDiv1_004844 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\3/C(=O)N(C)c4ccccc34)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M05 compound treatment 624347.0 70000.0 0.31 668819.0 84300.0 0.42 0.5168 0.99 1155316 ChemDiv1_004845 COc1cc(ccc1OCc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M06 compound treatment 604242.0 49900.0 0.22 677269.0 92700.0 0.46 0.4828 0.9452 1385987 ChemDiv1_004846 Brc1ccc(cc1)c2cn3ccc4ccccc4c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M07 compound treatment 745499.0 191000.0 0.86 690349.0 106000.0 0.52 0.9757 0.9723 1544072 ChemDiv1_004847 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc(nc5ccccc45)c6ccncc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M08 compound treatment 682317.0 128000.0 0.57 655103.0 70600.0 0.35 0.6523 0.9719 1972655 ChemDiv1_004848 Cc1cccc(NC2=NC(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/S2)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M09 compound treatment 688531.0 134000.0 0.6 690753.0 106000.0 0.53 0.7968 0.9978 1972656 ChemDiv1_004849 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M10 compound treatment 733668.0 179000.0 0.8 782109.0 198000.0 0.98 1.2597 0.9952 1972657 ChemDiv1_004850 COc1ccc(/C=C/2\SC(=NC2=O)N3CCN(CC3)C(=O)CCN4C(=O)\C(=C/c5cccs5)\SC4=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M11 compound treatment 725313.0 171000.0 0.77 701002.0 116000.0 0.58 0.9492 0.9903 1972658 ChemDiv1_004851 Cc1cc(C)nc(Sc2nnc(C)c3ccccc23)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M12 compound treatment 709837.0 156000.0 0.7 698718.0 114000.0 0.57 0.8922 0.9947 1923709 ChemDiv1_004852 Cc1nnc(NC(=O)CN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M13 compound treatment 726114.0 172000.0 0.77 700528.0 116000.0 0.57 0.95 0.9897 1450129 ChemDiv1_004853 Cc1cccc(OC(=O)CSc2nnc(C)c3ccccc23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M14 compound treatment 723962.0 170000.0 0.76 687423.0 103000.0 0.51 0.8973 0.9812 1948374 ChemDiv1_004854 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCCn4ccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M15 compound treatment 714161.0 160000.0 0.72 664960.0 80400.0 0.4 0.7876 0.9618 1972659 ChemDiv1_004855 CCSc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M16 compound treatment 710234.0 156000.0 0.7 664204.0 79700.0 0.39 0.7725 0.9636 1785232 ChemDiv1_004856 Cc1sc2nc(SCC(=O)N3CCN(CCO)CC3)[nH]c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M17 compound treatment 862446.0 308000.0 1.38 813094.0 229000.0 1.13 1.7759 0.9952 1972660 ChemDiv1_004857 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(cc3OC)N(CC)CC)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M18 compound treatment 647903.0 93600.0 0.42 684137.0 99600.0 0.49 0.6451 0.9967 1647899 ChemDiv1_004858 CC(C)CCSc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(=C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M19 compound treatment 726207.0 172000.0 0.77 708513.0 124000.0 0.61 0.9783 0.9938 1972661 ChemDiv1_004859 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)c(C)n1c4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M20 compound treatment 666462.0 112000.0 0.5 671654.0 87100.0 0.43 0.6601 0.9972 1972662 ChemDiv1_004860 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-])cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M21 compound treatment 751655.0 197000.0 0.88 706350.0 122000.0 0.6 1.0513 0.9827 1972663 ChemDiv1_004861 COc1cc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)ccc1OCc4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M22 compound treatment 690162.0 136000.0 0.61 655897.0 71300.0 0.35 0.6799 0.9667 1725655 ChemDiv1_004862 CS(=O)(=O)c1ccc2nc(NC(=O)CN3C(=O)CCC3=O)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M23 mock treatment 711354.0 157000.0 0.7 658371.0 73800.0 0.37 0.7556 0.9536 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 M24 mock treatment 493523.0 -60800.0 -0.27 393765.0 -191000.0 -0.95 -0.8607 -0.8752 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N01 compound treatment 627176.0 72900.0 0.33 588539.0 3990.0 0.02 0.2446 0.7486 1350036 ChemDiv1_004863 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N02 compound treatment 654588.0 100000.0 0.45 609501.0 25000.0 0.12 0.4048 0.8695 1242815 ChemDiv1_004864 Cc1cc(C)nc(NC(c2ccco2)c3ccc4cccnc4c3O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N03 compound treatment 692111.0 138000.0 0.62 651534.0 67000.0 0.33 0.6708 0.9577 1149633 ChemDiv1_004865 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2c3CSCc3nn2c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N04 compound treatment 659204.0 105000.0 0.47 633493.0 48900.0 0.24 0.5034 0.9527 1948325 ChemDiv1_004866 Clc1ccc(cc1)S(=O)(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N05 compound treatment 669579.0 115000.0 0.52 660318.0 75800.0 0.38 0.6302 0.9878 1675405 ChemDiv1_004867 COc1ccc(cc1)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N06 compound treatment 667776.0 113000.0 0.51 645125.0 60600.0 0.3 0.5713 0.9685 1972664 ChemDiv1_004868 OCCN1CCN(CC1)C(c2ccc(cc2)C(F)(F)F)c3ccc4cccnc4c3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N07 compound treatment 720282.0 166000.0 0.74 714643.0 130000.0 0.64 0.981 0.9975 1125763 ChemDiv1_004869 CCOc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(OC)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N08 compound treatment 670016.0 116000.0 0.52 672224.0 87700.0 0.43 0.6733 0.9962 1972665 ChemDiv1_004870 O=C(CSc1nnc2ccccn12)NCc3ccco3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N09 compound treatment 682776.0 128000.0 0.58 708825.0 124000.0 0.62 0.8419 0.9994 1972666 ChemDiv1_004871 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(cc3)[N+](=O)[O-])c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N10 compound treatment 671995.0 118000.0 0.53 672000.0 87500.0 0.43 0.6788 0.9953 1949865 ChemDiv1_004872 Cc1sc2nc(SCC(=O)NCc3cccnc3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N11 compound treatment 727045.0 173000.0 0.77 723175.0 139000.0 0.69 1.0323 0.9983 1944642 ChemDiv1_004873 COc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OCc3ccccc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N12 compound treatment 688727.0 134000.0 0.6 675207.0 90700.0 0.45 0.743 0.9896 1486916 ChemDiv1_004874 O=C1C2C3CC(C=C3)C2C(=O)N1CCN4CCN(CC4)S(=O)(=O)c5ccc6ccccc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N13 compound treatment 743918.0 190000.0 0.85 788404.0 204000.0 1.01 1.3142 0.9963 1572127 ChemDiv1_004875 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(Cl)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N14 compound treatment 678937.0 125000.0 0.56 693464.0 109000.0 0.54 0.776 0.9999 1951731 ChemDiv1_004876 Cc1sc2nc(SCC(=O)N3CCOCC3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N15 compound treatment 696016.0 142000.0 0.63 723560.0 139000.0 0.69 0.9354 0.9992 1436157 ChemDiv1_004877 CSc1nc2ccc(NC(=O)CN3C(=O)c4ccccc4C3=O)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N16 compound treatment 694688.0 140000.0 0.63 675259.0 90700.0 0.45 0.762 0.9865 1941313 ChemDiv1_004878 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCN6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N17 compound treatment 685376.0 131000.0 0.59 692852.0 108000.0 0.54 0.7942 0.999 1972667 ChemDiv1_004879 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N18 compound treatment 696262.0 142000.0 0.64 709184.0 125000.0 0.62 0.8859 0.9999 1972668 ChemDiv1_004880 OC(=O)CCCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N19 compound treatment 688324.0 134000.0 0.6 720556.0 136000.0 0.67 0.9006 0.9983 1940006 ChemDiv1_004881 Cc1c(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N20 compound treatment 682230.0 128000.0 0.57 695836.0 111000.0 0.55 0.7947 0.9998 1731664 ChemDiv1_004882 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N21 compound treatment 719600.0 165000.0 0.74 689352.0 105000.0 0.52 0.8903 0.985 1945143 ChemDiv1_004883 COC(=O)c1ccc(CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N22 compound treatment 675197.0 121000.0 0.54 676139.0 91600.0 0.45 0.7034 0.9962 1972669 ChemDiv1_004884 COc1ccccc1C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N23 mock treatment 651173.0 96900.0 0.43 653338.0 68800.0 0.34 0.5475 0.9929 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 N24 mock treatment 400256.0 -154000.0 -0.69 404349.0 -180000.0 -0.89 -1.1189 -0.9919 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O01 compound treatment 642573.0 88300.0 0.4 560747.0 -23800.0 -0.12 0.196 0.4753 1535719 ChemDiv1_004885 Cc1ccc(Nc2nc3nonc3nc2NC4C5CC6CC(C5)CC4C6)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O02 compound treatment 651903.0 97600.0 0.44 573705.0 -10800.0 -0.05 0.2709 0.6155 1528553 ChemDiv1_004886 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)sc4CC(C)CCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O03 compound treatment 696367.0 142000.0 0.64 602608.0 18100.0 0.09 0.5129 0.7987 1343072 ChemDiv1_004887 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(F)cc4F)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O04 compound treatment 713585.0 159000.0 0.71 627482.0 42900.0 0.21 0.6545 0.8797 1972670 ChemDiv1_004888 COc1ccc(cc1)S(=O)(=O)/N=C\2/NC(=O)/C(=C\c3ccc(OC)c(OC)c3)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O05 compound treatment 708940.0 155000.0 0.69 613411.0 28900.0 0.14 0.5905 0.8355 1633492 ChemDiv1_004889 CCOC(=O)c1ccc(Nc2nc3nonc3nc2N(CC)CC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O06 compound treatment 664145.0 110000.0 0.49 618044.0 33500.0 0.17 0.465 0.8961 1972671 ChemDiv1_004890 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O07 compound treatment 703789.0 149000.0 0.67 654091.0 69500.0 0.34 0.7167 0.9524 1972672 ChemDiv1_004891 Clc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O08 compound treatment 738261.0 184000.0 0.82 679866.0 95300.0 0.47 0.9161 0.9652 1972673 ChemDiv1_004892 COc1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccs3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O09 compound treatment 679204.0 125000.0 0.56 666733.0 82200.0 0.41 0.6832 0.9879 1972674 ChemDiv1_004893 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nn3c(nc4ccccc4c3=O)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O10 compound treatment 768387.0 214000.0 0.96 733964.0 149000.0 0.74 1.201 0.9919 1972675 ChemDiv1_004894 O=C(CCN1C(=O)/C(=C\c2cccs2)/SC1=S)N3c4ccccc4Sc5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O11 compound treatment 669653.0 115000.0 0.52 654087.0 69500.0 0.34 0.6086 0.9807 1972676 ChemDiv1_004895 Cc1nnc(SCC(=O)N)c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O12 compound treatment 721499.0 167000.0 0.75 672229.0 87700.0 0.43 0.8363 0.9665 1972677 ChemDiv1_004896 COc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O13 compound treatment 696101.0 142000.0 0.63 667305.0 82800.0 0.41 0.7387 0.9776 1719439 ChemDiv1_004897 Cc1nn(CC(=O)Nc2ccc(Cl)cc2Cl)c(=O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O14 compound treatment 678555.0 124000.0 0.56 622735.0 38200.0 0.19 0.527 0.8972 1947764 ChemDiv1_004898 Cc1sc2nc(SCC(=O)NCCCn3ccnc3)[nH]c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O15 compound treatment 727867.0 174000.0 0.78 675339.0 90800.0 0.45 0.8673 0.9662 1946934 ChemDiv1_004899 CCSc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O16 compound treatment 700442.0 146000.0 0.65 634302.0 49800.0 0.25 0.6368 0.911 1948644 ChemDiv1_004900 CCOC(=O)CSc1nnc(c2cccc(OC)c2)n1c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O17 compound treatment 1275511.0 721000.0 3.23 1184270.0 600000.0 2.97 4.3835 0.9991 1972678 ChemDiv1_004901 OC(=O)c1ccccc1c2ccc(/C=C\3/C(=O)NC(=S)N(C3=O)c4ccc(Br)cc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O18 compound treatment 695419.0 141000.0 0.63 637988.0 53400.0 0.26 0.6338 0.9255 1280842 ChemDiv1_004902 COc1ccccc1C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O19 compound treatment 722678.0 168000.0 0.75 672885.0 88300.0 0.44 0.8423 0.9666 1972679 ChemDiv1_004903 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)c(C)n1c4cccc(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O20 compound treatment 684016.0 130000.0 0.58 646495.0 61900.0 0.31 0.6275 0.9556 1972680 ChemDiv1_004904 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4c(C)onc4c5ccccc5Cl)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O21 compound treatment 713929.0 160000.0 0.71 654335.0 69800.0 0.35 0.7497 0.9445 1972681 ChemDiv1_004905 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(o3)c4ccccc4[N+](=O)[O-])/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O22 compound treatment 643074.0 88800.0 0.4 621700.0 37200.0 0.18 0.4111 0.9388 1972682 ChemDiv1_004906 [O-][N+](=O)c1ccc2sc(cc2c1)C(=O)Nc3ccc(Br)cc3C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O23 mock treatment 677174.0 123000.0 0.55 638583.0 54000.0 0.27 0.5781 0.9453 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 O24 mock treatment 188356.0 -366000.0 -1.64 401680.0 -183000.0 -0.91 -1.7989 -0.961 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P01 compound treatment 615031.0 60700.0 0.27 558200.0 -26300.0 -0.13 0.0999 0.3313 1450296 ChemDiv1_004907 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P02 compound treatment 613481.0 59200.0 0.26 574809.0 -9740.0 -0.05 0.1531 0.5689 1560844 ChemDiv1_004908 Clc1c(sc2ccccc12)C(=O)Nc3nc(cs3)c4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P03 compound treatment 623701.0 69400.0 0.31 583196.0 -1350.0 -0.01 0.2149 0.6917 1740134 ChemDiv1_004909 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P04 compound treatment 588440.0 34100.0 0.15 573680.0 -10900.0 -0.05 0.0699 0.4318 1972683 ChemDiv1_004910 O=C(/C=C/c1ccc2OCOc2c1)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P05 compound treatment 590886.0 36600.0 0.16 607460.0 22900.0 0.11 0.196 0.984 1128943 ChemDiv1_004911 COc1ccc(cc1)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P06 compound treatment 626801.0 72500.0 0.32 609551.0 25000.0 0.12 0.317 0.9128 1366639 ChemDiv1_004912 Fc1ccc(cc1)c2csc3ncnc(NCCc4ccc5OCOc5c4)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P07 compound treatment 664859.0 111000.0 0.49 609486.0 24900.0 0.12 0.4372 0.8573 1972684 ChemDiv1_004913 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)OC)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P08 compound treatment 684389.0 130000.0 0.58 629222.0 44700.0 0.22 0.5682 0.9122 1972685 ChemDiv1_004914 COc1ccc(cc1OC)c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P09 compound treatment 647684.0 93400.0 0.42 612621.0 28100.0 0.14 0.3939 0.8942 1737154 ChemDiv1_004915 COc1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4ccc(Br)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P10 compound treatment 648777.0 94500.0 0.42 615803.0 31300.0 0.15 0.4085 0.9071 1941283 ChemDiv1_004916 OCCCNC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P11 compound treatment 666512.0 112000.0 0.5 593638.0 9090.0 0.05 0.387 0.7674 1972686 ChemDiv1_004917 [O-][N+](=O)c1cccc(c1)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P12 compound treatment 652817.0 98500.0 0.44 611576.0 27000.0 0.13 0.4064 0.8821 1972687 ChemDiv1_004918 O=C1C2C3CC(C=C3)C2C(=O)N1CCN4CCN(CC4)S(=O)(=O)/C=C\c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P13 compound treatment 656405.0 102000.0 0.46 609536.0 25000.0 0.12 0.4107 0.8674 1873279 ChemDiv1_004919 CCCOC(=O)CSC1=C(C#N)C(C(C(=O)OC)C(=O)N1)c2ccc(Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P14 compound treatment 653010.0 98700.0 0.44 599984.0 15400.0 0.08 0.3664 0.8174 1310399 ChemDiv1_004920 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P15 compound treatment 647697.0 93400.0 0.42 610604.0 26100.0 0.13 0.3868 0.8843 1972688 ChemDiv1_004921 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)CN3C(=O)c4ccccc4C3=O)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P16 compound treatment 671139.0 117000.0 0.52 611627.0 27100.0 0.13 0.4646 0.8606 1924339 ChemDiv1_004922 CCCCN(CCCC)C(=O)CSc1nc2sc(C)c(C)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P17 compound treatment 666406.0 112000.0 0.5 613962.0 29400.0 0.15 0.4578 0.8763 1670644 ChemDiv1_004923 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5[nH]4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P18 compound treatment 652000.0 97700.0 0.44 610752.0 26200.0 0.13 0.401 0.8791 1591656 ChemDiv1_004924 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P19 compound treatment 657089.0 103000.0 0.46 621085.0 36500.0 0.18 0.4533 0.9169 1379692 ChemDiv1_004925 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P20 compound treatment 658485.0 104000.0 0.47 635149.0 50600.0 0.25 0.507 0.9576 1518000 ChemDiv1_004926 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P21 compound treatment 628942.0 74600.0 0.33 596383.0 11800.0 0.06 0.2777 0.8187 1155193 ChemDiv1_004927 OCCN(CCO)C(=O)CSc1nc2sc3CCCCc3c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P22 compound treatment 646374.0 92100.0 0.41 616035.0 31500.0 0.16 0.4017 0.9116 1972689 ChemDiv1_004928 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P23 mock treatment 605196.0 50900.0 0.23 605846.0 21300.0 0.11 0.2356 0.9388 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.600 P24 mock treatment 433034.0 -121000.0 -0.54 140680.0 -444000.0 -2.2 -1.9387 -0.856 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A01 compound treatment 556122.0 -18000.0 -0.08 570431.0 6240.0 0.03 -0.0351 -0.4072 1729876 ChemDiv1_004929 CCOc1ccc2cc(C3CC(=NN3C(=O)C)c4ccccc4)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A02 compound treatment 533870.0 -40300.0 -0.18 577589.0 13400.0 0.07 -0.0805 -0.4192 1742286 ChemDiv1_004930 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A03 compound treatment 548057.0 -26100.0 -0.12 583527.0 19300.0 0.1 -0.0148 -0.098 1446629 ChemDiv1_004931 Cn1c(=O)n(C)c2nc(N3CCCCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A04 compound treatment 539582.0 -34500.0 -0.15 595102.0 30900.0 0.15 -0.0011 -0.005 1319177 ChemDiv1_004932 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A05 compound treatment 558249.0 -15900.0 -0.07 594153.0 30000.0 0.15 0.0547 0.3323 1972690 ChemDiv1_004933 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(=O)[nH]c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A06 compound treatment 586418.0 12300.0 0.06 604113.0 39900.0 0.2 0.1787 0.8708 1338932 ChemDiv1_004934 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A07 compound treatment 641628.0 67500.0 0.3 684997.0 121000.0 0.6 0.6368 0.9499 1639329 ChemDiv1_004935 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A08 compound treatment 602848.0 28700.0 0.13 638503.0 74300.0 0.37 0.3512 0.9007 1508865 ChemDiv1_004936 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4sc(C)nc4c3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A09 compound treatment 592395.0 18300.0 0.08 621492.0 57300.0 0.28 0.2585 0.8752 1972691 ChemDiv1_004937 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A10 compound treatment 599805.0 25700.0 0.11 627160.0 63000.0 0.31 0.3018 0.908 1697271 ChemDiv1_004938 O=C(Nc1nc-2c(CCc3ccccc23)s1)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A11 compound treatment 594472.0 20300.0 0.09 605102.0 40900.0 0.2 0.2077 0.9348 1555460 ChemDiv1_004939 CCOc1ccc(NC(=O)Nc2nc(cs2)c3ccc(Oc4ccccc4)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A12 compound treatment 589673.0 15500.0 0.07 622570.0 58400.0 0.29 0.2537 0.8529 1972692 ChemDiv1_004940 Clc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4)C(=O)CN5CCOCC5)c(c6ccccc6)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A13 compound treatment 610736.0 36600.0 0.16 629813.0 65600.0 0.33 0.3457 0.9497 1972693 ChemDiv1_004941 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A14 compound treatment 608176.0 34000.0 0.15 624036.0 59800.0 0.3 0.3174 0.9522 1646534 ChemDiv1_004942 CSc1nc2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A15 compound treatment 617688.0 43600.0 0.19 603430.0 39200.0 0.19 0.2753 1.0 1372115 ChemDiv1_004943 COc1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A16 compound treatment 598585.0 24500.0 0.11 630068.0 65900.0 0.33 0.3082 0.8953 1354587 ChemDiv1_004944 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A17 compound treatment 589946.0 15800.0 0.07 640619.0 76400.0 0.38 0.3178 0.8251 1349292 ChemDiv1_004945 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A18 compound treatment 598833.0 24700.0 0.11 615902.0 51700.0 0.26 0.2593 0.9295 1972694 ChemDiv1_004946 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A19 compound treatment 592938.0 18800.0 0.08 611806.0 47600.0 0.24 0.2263 0.9037 1344207 ChemDiv1_004947 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A20 compound treatment 567212.0 -6910.0 -0.03 599366.0 35200.0 0.17 0.1013 0.5725 1972695 ChemDiv1_004948 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccc(c3)[N+](=O)[O-])c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A21 compound treatment 556770.0 -17400.0 -0.08 603489.0 39300.0 0.19 0.0827 0.3946 1874356 ChemDiv1_004949 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A22 compound treatment 559885.0 -14200.0 -0.06 580735.0 16500.0 0.08 0.0129 0.1238 1549475 ChemDiv1_004950 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccc(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A23 mock treatment 543953.0 -30200.0 -0.14 582435.0 18200.0 0.09 -0.0316 -0.1946 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 A24 mock treatment 222086.0 -352000.0 -1.58 504044.0 -60200.0 -0.3 -1.325 -0.8262 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B01 compound treatment 569566.0 -4560.0 -0.02 595643.0 31400.0 0.16 0.0957 0.6092 1592111 ChemDiv1_004951 CC1=C(C(c2ccccn2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B02 compound treatment 624982.0 50900.0 0.23 624772.0 60600.0 0.3 0.3732 0.9907 1608435 ChemDiv1_004952 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(Br)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B03 compound treatment 649932.0 75800.0 0.34 700213.0 136000.0 0.67 0.7164 0.9496 1636130 ChemDiv1_004953 CC1=C(C(c2ccc3OCOc3c2)n4ncnc4N1)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B04 compound treatment 622837.0 48700.0 0.22 693320.0 129000.0 0.64 0.6065 0.8974 1265027 ChemDiv1_004954 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc(cs3)c4cc5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B05 compound treatment 683356.0 109000.0 0.49 720367.0 156000.0 0.77 0.8928 0.9755 1265414 ChemDiv1_004955 Cc1ccccc1n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B06 compound treatment 631834.0 57700.0 0.26 691774.0 128000.0 0.63 0.6296 0.9221 1178364 ChemDiv1_004956 NC(=O)c1oc2ccccc2c1NC(=O)c3cc(nc4ccccc34)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B07 compound treatment 724326.0 150000.0 0.67 751129.0 187000.0 0.93 1.1302 0.9876 1195190 ChemDiv1_004957 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B08 compound treatment 712294.0 138000.0 0.62 735144.0 171000.0 0.85 1.0361 0.9881 1972696 ChemDiv1_004958 OC(COc1ccc(Cl)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B09 compound treatment 665359.0 91200.0 0.41 749338.0 185000.0 0.92 0.9373 0.9336 1493865 ChemDiv1_004959 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B10 compound treatment 669807.0 95700.0 0.43 747545.0 183000.0 0.91 0.9451 0.9412 1972697 ChemDiv1_004960 COc1cccc(OC)c1OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B11 compound treatment 683734.0 110000.0 0.49 756566.0 192000.0 0.95 1.0208 0.9524 1420229 ChemDiv1_004961 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B12 compound treatment 669937.0 95800.0 0.43 693634.0 129000.0 0.64 0.7567 0.9809 1972698 ChemDiv1_004962 O=C1N(CC2CCN(CC2)S(=O)(=O)/C=C/c3ccccc3)C(=O)c4cccc5cccc1c45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B13 compound treatment 695965.0 122000.0 0.55 781331.0 217000.0 1.08 1.1462 0.9504 1924867 ChemDiv1_004963 COc1ccc2c(Cl)c(sc2c1)C(=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B14 compound treatment 711664.0 138000.0 0.62 757861.0 194000.0 0.96 1.1137 0.977 1972699 ChemDiv1_004964 CCOC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)scc1c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B15 compound treatment 719058.0 145000.0 0.65 775596.0 211000.0 1.05 1.1993 0.9735 1972700 ChemDiv1_004965 CCOC(=O)c1c(C)oc2cc(Br)c(OC/C=C/c3ccccc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B16 compound treatment 691045.0 117000.0 0.52 746243.0 182000.0 0.9 1.0078 0.9665 1972701 ChemDiv1_004966 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC6CC7CC(C6)C5)C7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B17 compound treatment 713944.0 140000.0 0.63 774885.0 211000.0 1.04 1.1806 0.9701 1195179 ChemDiv1_004967 COC(=O)c1c(C)oc2cc(Br)c(OCc3c(F)cccc3Cl)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B18 compound treatment 689682.0 116000.0 0.52 726936.0 163000.0 0.81 0.9358 0.977 1972702 ChemDiv1_004968 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc(cc3)[N+](=O)[O-])c(NC4CCCCC4)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B19 compound treatment 684758.0 111000.0 0.5 764364.0 200000.0 0.99 1.0513 0.9485 1972703 ChemDiv1_004969 CCOC(=O)CSc1nnc(CSc2nc3sc4CCCc4c3c(=O)[nH]2)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B20 compound treatment 645453.0 71300.0 0.32 716351.0 152000.0 0.75 0.7587 0.9269 1531948 ChemDiv1_004970 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1CC(O)COc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B21 compound treatment 662603.0 88500.0 0.4 743799.0 180000.0 0.89 0.9092 0.9336 1176170 ChemDiv1_004971 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B22 compound treatment 612477.0 38400.0 0.17 707401.0 143000.0 0.71 0.623 0.8536 1728356 ChemDiv1_004972 Cc1cc(C)c(NC(=O)Cn2c3ccccc3c4nc5ccccc5nc24)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B23 mock treatment 638076.0 63900.0 0.29 680176.0 116000.0 0.57 0.6087 0.9482 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 B24 mock treatment 546839.0 -27300.0 -0.12 543512.0 -20700.0 -0.1 -0.1588 -0.9962 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C01 compound treatment 572319.0 -1810.0 -0.01 577762.0 13600.0 0.07 0.0418 0.6175 1163610 ChemDiv1_004973 CCOc1ccc2cc(C3CC(=NN3C(=O)C)c4ccc(C)cc4)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C02 compound treatment 580390.0 6260.0 0.03 641352.0 77200.0 0.38 0.2901 0.7569 1625743 ChemDiv1_004974 CC1=C(C(c2ccccc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C03 compound treatment 645380.0 71300.0 0.32 680873.0 117000.0 0.58 0.6342 0.9607 1596638 ChemDiv1_004975 Cn1c(=O)n(C)c2nc(N3CCOCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C04 compound treatment 629928.0 55800.0 0.25 672416.0 108000.0 0.54 0.5557 0.9396 1233417 ChemDiv1_004976 CC1=C(C(c2ccc(OC(=O)c3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C05 compound treatment 652944.0 78800.0 0.35 688777.0 125000.0 0.62 0.6859 0.9648 1400572 ChemDiv1_004977 CCC(=O)N1N=C(CC1Cc2cc3cccc(C)c3[nH]c2=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C06 compound treatment 640670.0 66500.0 0.3 685741.0 122000.0 0.6 0.6364 0.9473 1972704 ChemDiv1_004978 CC1=C(C(c2ccc(cc2)[N+](=O)[O-])n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C07 compound treatment 674448.0 100000.0 0.45 738249.0 174000.0 0.86 0.9272 0.9538 1489378 ChemDiv1_004979 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C08 compound treatment 700269.0 126000.0 0.56 705024.0 141000.0 0.7 0.8926 0.9945 1482919 ChemDiv1_004980 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCCC5)sc32)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C09 compound treatment 714949.0 141000.0 0.63 763325.0 199000.0 0.99 1.1433 0.9766 1972705 ChemDiv1_004981 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C10 compound treatment 668833.0 94700.0 0.42 709972.0 146000.0 0.72 0.8104 0.9678 1972706 ChemDiv1_004982 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C11 compound treatment 684987.0 111000.0 0.5 758886.0 195000.0 0.96 1.0329 0.9523 1742235 ChemDiv1_004983 COc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C12 compound treatment 634773.0 60600.0 0.27 720600.0 156000.0 0.77 0.7398 0.9011 1972707 ChemDiv1_004984 Clc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccccc4Cl)C(=O)CN5CCOCC5)c(c6ccccc6)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C13 compound treatment 720901.0 147000.0 0.66 732042.0 168000.0 0.83 1.0525 0.9932 1458516 ChemDiv1_004985 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C14 compound treatment 724116.0 150000.0 0.67 741335.0 177000.0 0.88 1.0953 0.9913 1565441 ChemDiv1_004986 CC1(C)CC(=O)c2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)nc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C15 compound treatment 721493.0 147000.0 0.66 751082.0 187000.0 0.93 1.1211 0.9862 1469942 ChemDiv1_004987 COc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C16 compound treatment 677968.0 104000.0 0.46 714383.0 150000.0 0.74 0.8548 0.9744 1220811 ChemDiv1_004988 CN(c1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5sc(C)nc5c4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C17 compound treatment 689943.0 116000.0 0.52 748646.0 184000.0 0.91 1.0127 0.964 1371528 ChemDiv1_004989 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C18 compound treatment 656530.0 82400.0 0.37 695319.0 131000.0 0.65 0.7201 0.9641 1302789 ChemDiv1_004990 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C19 compound treatment 647497.0 73400.0 0.33 720723.0 157000.0 0.78 0.7805 0.9269 1686659 ChemDiv1_004991 CC1=C(C(c2ccc(Br)cc2)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C20 compound treatment 695063.0 121000.0 0.54 776513.0 212000.0 1.05 1.1265 0.9523 1972708 ChemDiv1_004992 CNC(=S)N1N=C(CC1c2ccc(cc2)N(C)C)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C21 compound treatment 644475.0 70300.0 0.31 712789.0 149000.0 0.74 0.7432 0.9282 1472593 ChemDiv1_004993 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C22 compound treatment 624820.0 50700.0 0.23 677364.0 113000.0 0.56 0.5569 0.9208 1287914 ChemDiv1_004994 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)c(OCC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C23 mock treatment 633913.0 59800.0 0.27 652980.0 88800.0 0.44 0.5002 0.9716 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 C24 mock treatment 317918.0 -256000.0 -1.15 492309.0 -71900.0 -0.36 -1.0628 -0.885 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D01 compound treatment 584457.0 10300.0 0.05 607636.0 43400.0 0.22 0.1849 0.8399 1123174 ChemDiv1_004995 CC1=C(C(c2cccc(Br)c2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D02 compound treatment 631619.0 57500.0 0.26 661454.0 97300.0 0.48 0.5227 0.9569 1972709 ChemDiv1_004996 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(cc4s3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D03 compound treatment 657568.0 83400.0 0.37 689372.0 125000.0 0.62 0.7026 0.9706 1611784 ChemDiv1_004997 CC1=C(C(c2ccccn2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D04 compound treatment 657559.0 83400.0 0.37 690684.0 126000.0 0.63 0.7072 0.9694 1972710 ChemDiv1_004998 CS(=O)(=O)c1ccc2nc(NC(=S)NC(=O)c3cc4cc(ccc4s3)[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D05 compound treatment 682689.0 109000.0 0.49 736806.0 173000.0 0.86 0.9483 0.9641 1249513 ChemDiv1_004999 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D06 compound treatment 664213.0 90100.0 0.4 700406.0 136000.0 0.67 0.7623 0.9697 1972711 ChemDiv1_005000 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D07 compound treatment 677759.0 104000.0 0.46 714669.0 150000.0 0.75 0.8551 0.974 1972712 ChemDiv1_005001 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D08 compound treatment 722212.0 148000.0 0.66 741078.0 177000.0 0.88 1.0883 0.9905 1972713 ChemDiv1_005002 OC(COc1ccc2OCOc2c1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D09 compound treatment 745678.0 172000.0 0.77 776251.0 212000.0 1.05 1.2858 0.9881 1704023 ChemDiv1_005003 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D10 compound treatment 711848.0 138000.0 0.62 737724.0 174000.0 0.86 1.0438 0.9867 1972714 ChemDiv1_005004 OC(COc1ccccc1F)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D11 compound treatment 743196.0 169000.0 0.76 812786.0 249000.0 1.23 1.4059 0.9727 1392853 ChemDiv1_005005 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D12 compound treatment 683773.0 110000.0 0.49 738012.0 174000.0 0.86 0.9559 0.9645 1972715 ChemDiv1_005006 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D13 compound treatment 672327.0 98200.0 0.44 737707.0 174000.0 0.86 0.9186 0.9515 1924918 ChemDiv1_005007 COc1ccc(/C=C/C(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D14 compound treatment 732565.0 158000.0 0.71 756441.0 192000.0 0.95 1.1749 0.9895 1972716 ChemDiv1_005008 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc(Cl)c1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D15 compound treatment 741158.0 167000.0 0.75 795057.0 231000.0 1.14 1.3374 0.9788 1972717 ChemDiv1_005009 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D16 compound treatment 669649.0 95500.0 0.43 756737.0 193000.0 0.95 0.9768 0.9345 1972718 ChemDiv1_005010 CCOC(=O)c1c(NC(=O)CN2C(=O)c3cccc4cccc(C2=O)c34)sc5CCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D17 compound treatment 696966.0 123000.0 0.55 789204.0 225000.0 1.11 1.177 0.947 1249548 ChemDiv1_005011 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCc4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D18 compound treatment 685079.0 111000.0 0.5 736721.0 173000.0 0.85 0.9555 0.9667 1972719 ChemDiv1_005012 COc1ccc(OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)[nH]c(=O)c24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D19 compound treatment 708414.0 134000.0 0.6 750242.0 186000.0 0.92 1.0768 0.9786 1281706 ChemDiv1_005013 C=CCn1c(SCC(=O)NCCN2CCOCC2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D20 compound treatment 700763.0 127000.0 0.57 729965.0 166000.0 0.82 0.9815 0.9836 1496925 ChemDiv1_005014 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCCCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D21 compound treatment 677411.0 103000.0 0.46 766836.0 203000.0 1.0 1.0367 0.9381 1557814 ChemDiv1_005015 O=C(Nc1nc2ccccc2c3nc4ccccc4n13)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D22 compound treatment 657206.0 83100.0 0.37 753859.0 190000.0 0.94 0.9273 0.9177 1972720 ChemDiv1_005016 O=c1n(nc2-c3ccccc3-c4cccc1c42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D23 mock treatment 641305.0 67200.0 0.3 716117.0 152000.0 0.75 0.7448 0.919 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 D24 mock treatment 527374.0 -46800.0 -0.21 536826.0 -27400.0 -0.14 -0.2439 -0.9779 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E01 compound treatment 597757.0 23600.0 0.11 594681.0 30500.0 0.15 0.1816 0.9848 1600069 ChemDiv1_005017 CCOc1ccc2cc(C3CC(=NN3C(=O)CC)c4ccc(Br)cc4)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E02 compound treatment 600993.0 26900.0 0.12 645539.0 81300.0 0.4 0.37 0.8798 1643936 ChemDiv1_005018 CC1=C(C(c2ccc(Cl)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E03 compound treatment 654864.0 80700.0 0.36 710401.0 146000.0 0.72 0.7677 0.9484 1298851 ChemDiv1_005019 Cn1c(=O)n(C)c2nc(NCc3ccccc3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E04 compound treatment 650242.0 76100.0 0.34 705379.0 141000.0 0.7 0.7355 0.9454 1393931 ChemDiv1_005020 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E05 compound treatment 694128.0 120000.0 0.54 729430.0 165000.0 0.82 0.9586 0.9791 1501606 ChemDiv1_005021 Cc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4nc3Cl)C2)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E06 compound treatment 668003.0 93900.0 0.42 643327.0 79100.0 0.39 0.5743 0.9994 1252430 ChemDiv1_005022 COc1ccc(cc1)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E07 compound treatment 846875.0 273000.0 1.22 931967.0 368000.0 1.82 2.1516 0.9811 1972721 ChemDiv1_005023 Cc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E08 compound treatment 708888.0 135000.0 0.6 729678.0 165000.0 0.82 1.0062 0.9886 1367218 ChemDiv1_005024 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5sc(C)nc5c4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E09 compound treatment 703881.0 130000.0 0.58 771028.0 207000.0 1.02 1.1352 0.9639 1972722 ChemDiv1_005025 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E10 compound treatment 683406.0 109000.0 0.49 721051.0 157000.0 0.78 0.8953 0.9751 1972723 ChemDiv1_005026 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E11 compound treatment 738158.0 164000.0 0.73 754820.0 191000.0 0.94 1.1869 0.9923 1203903 ChemDiv1_005027 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E12 compound treatment 699290.0 125000.0 0.56 730391.0 166000.0 0.82 0.9783 0.9824 1972724 ChemDiv1_005028 COc1ccccc1C2CC(=NN2C(=O)CN3CCOCC3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E13 compound treatment 718977.0 145000.0 0.65 737758.0 174000.0 0.86 1.0665 0.9903 1972725 ChemDiv1_005029 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E14 compound treatment 691199.0 117000.0 0.52 727440.0 163000.0 0.81 0.9424 0.9779 1715807 ChemDiv1_005030 O=C(Nc1nc2CCCCc2s1)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E15 compound treatment 748303.0 174000.0 0.78 754672.0 190000.0 0.94 1.2185 0.9955 1139490 ChemDiv1_005031 COc1ccc(OC)c(c1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E16 compound treatment 680244.0 106000.0 0.48 738973.0 175000.0 0.87 0.9481 0.9601 1972726 ChemDiv1_005032 COCCN(CCOC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4sc(C)nc4c3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E17 compound treatment 719176.0 145000.0 0.65 770252.0 206000.0 1.02 1.1809 0.9761 1274051 ChemDiv1_005033 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4ncnc4N1)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E18 compound treatment 701925.0 128000.0 0.57 724615.0 160000.0 0.79 0.9664 0.987 1603959 ChemDiv1_005034 Clc1ccccc1C2CC(=NN2C(=O)c3cccs3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E19 compound treatment 675065.0 101000.0 0.45 731311.0 167000.0 0.83 0.9049 0.9594 1221179 ChemDiv1_005035 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E20 compound treatment 683400.0 109000.0 0.49 695549.0 131000.0 0.65 0.806 0.9901 1972727 ChemDiv1_005036 CC(=O)N1N=C(CC1c2ccc(Cl)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E21 compound treatment 682438.0 108000.0 0.48 702733.0 139000.0 0.69 0.8281 0.9855 1655176 ChemDiv1_005037 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E22 compound treatment 640198.0 66100.0 0.3 727829.0 164000.0 0.81 0.7823 0.9066 1685741 ChemDiv1_005038 CC1=C(C(c2cccc(Br)c2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E23 mock treatment 654916.0 80800.0 0.36 694418.0 130000.0 0.65 0.7119 0.9626 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 E24 mock treatment 496591.0 -77500.0 -0.35 267144.0 -297000.0 -1.47 -1.286 -0.8505 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F01 compound treatment 614940.0 40800.0 0.18 605762.0 41600.0 0.21 0.2748 0.9982 1237430 ChemDiv1_005039 CC1=C(C(c2ccc(O)cc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F02 compound treatment 638482.0 64400.0 0.29 653312.0 89100.0 0.44 0.5159 0.9786 1404506 ChemDiv1_005040 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5ccccc5c4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F03 compound treatment 674722.0 101000.0 0.45 705962.0 142000.0 0.7 0.815 0.9769 1737492 ChemDiv1_005041 CC1=C(C(c2ccc(O)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F04 compound treatment 660789.0 86700.0 0.39 699883.0 136000.0 0.67 0.7496 0.9659 1584826 ChemDiv1_005042 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(cc5CCc6cccc4c65)s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F05 compound treatment 701874.0 128000.0 0.57 735004.0 171000.0 0.85 1.0027 0.9818 1972728 ChemDiv1_005043 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F06 compound treatment 686580.0 112000.0 0.5 730070.0 166000.0 0.82 0.937 0.9723 1637874 ChemDiv1_005044 O=C(CSc1nc(cc(c2ccco2)c1C#N)C3CC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F07 compound treatment 723582.0 149000.0 0.67 764359.0 200000.0 0.99 1.1742 0.9817 1365371 ChemDiv1_005045 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(Oc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F08 compound treatment 717427.0 143000.0 0.64 731643.0 167000.0 0.83 1.0401 0.9919 1972729 ChemDiv1_005046 OC(COCc1ccc2OCOc2c1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F09 compound treatment 731460.0 157000.0 0.7 762436.0 198000.0 0.98 1.1924 0.9867 1709532 ChemDiv1_005047 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)C5CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F10 compound treatment 710223.0 136000.0 0.61 728989.0 165000.0 0.82 1.008 0.9896 1972730 ChemDiv1_005048 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F11 compound treatment 782237.0 208000.0 0.93 813691.0 249000.0 1.24 1.5327 0.9903 1418066 ChemDiv1_005049 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F12 compound treatment 709951.0 136000.0 0.61 735940.0 172000.0 0.85 1.0315 0.9864 1972731 ChemDiv1_005050 CS(=O)(=O)c1ccc2nc(NC(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F13 compound treatment 693764.0 120000.0 0.54 757064.0 193000.0 0.96 1.0543 0.9626 1925306 ChemDiv1_005051 O=C(/C=C/c1ccc2OCOc2c1)N3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F14 compound treatment 687706.0 114000.0 0.51 766544.0 202000.0 1.0 1.0683 0.9505 1972732 ChemDiv1_005052 COC(=O)c1ccc(cc1)n2c(C)cc(C(=O)CSc3nnc4sc5ccccc5n34)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F15 compound treatment 680407.0 106000.0 0.48 782033.0 218000.0 1.08 1.0995 0.9323 1233222 ChemDiv1_005053 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(Cl)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F16 compound treatment 702687.0 129000.0 0.58 748153.0 184000.0 0.91 1.0513 0.9754 1972733 ChemDiv1_005054 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC5)S(=O)(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F17 compound treatment 707863.0 134000.0 0.6 768889.0 205000.0 1.01 1.1403 0.9684 1924928 ChemDiv1_005055 O=C(CSc1nnc(CCCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6cccnc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F18 compound treatment 698783.0 125000.0 0.56 736738.0 173000.0 0.85 0.999 0.9786 1300937 ChemDiv1_005056 COc1ccc(OCC(O)Cn2c(NCc3ccco3)nc4n(C)c(=O)[nH]c(=O)c24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F19 compound treatment 714706.0 141000.0 0.63 760382.0 196000.0 0.97 1.1322 0.9779 1917640 ChemDiv1_005057 CCOC(=O)CSc1nnc(Nc2ccc(Cl)cc2)n1c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F20 compound treatment 686351.0 112000.0 0.5 676367.0 112000.0 0.56 0.7481 0.9987 1622264 ChemDiv1_005058 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCNCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F21 compound treatment 680354.0 106000.0 0.48 756292.0 192000.0 0.95 1.0091 0.9486 1126899 ChemDiv1_005059 O=C(Nc1nc2ccccc2c3nc4ccccc4n13)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F22 compound treatment 650628.0 76500.0 0.34 718426.0 154000.0 0.76 0.7824 0.9345 1261533 ChemDiv1_005060 CCN(CC)CCn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F23 mock treatment 652494.0 78400.0 0.35 703092.0 139000.0 0.69 0.7346 0.9511 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 F24 mock treatment 533095.0 -41000.0 -0.18 538519.0 -25700.0 -0.13 -0.2198 -0.9839 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G01 compound treatment 584068.0 9940.0 0.04 587292.0 23100.0 0.11 0.1124 0.9153 1972734 ChemDiv1_005061 COC(=O)c1ccccc1NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G02 compound treatment 630652.0 56500.0 0.25 623826.0 59600.0 0.3 0.3878 0.997 1391811 ChemDiv1_005062 CC1=C(C(c2ccccc2Cl)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G03 compound treatment 676898.0 103000.0 0.46 657887.0 93700.0 0.46 0.6535 1.0 1416557 ChemDiv1_005063 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2CC(O)COc4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G04 compound treatment 665193.0 91100.0 0.41 663296.0 99100.0 0.49 0.6354 0.9957 1492206 ChemDiv1_005064 CC1=C(C(c2ccccc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G05 compound treatment 704457.0 130000.0 0.58 715522.0 151000.0 0.75 0.9426 0.9923 1618081 ChemDiv1_005065 COc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4nc3Cl)C2)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G06 compound treatment 668328.0 94200.0 0.42 728686.0 164000.0 0.81 0.8744 0.953 1563220 ChemDiv1_005066 COc1ccc(cc1OC)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G07 compound treatment 750528.0 176000.0 0.79 783475.0 219000.0 1.09 1.3265 0.9877 1665643 ChemDiv1_005067 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3cccs3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G08 compound treatment 708804.0 135000.0 0.6 712390.0 148000.0 0.73 0.9454 0.9952 1180794 ChemDiv1_005068 COc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G09 compound treatment 749071.0 175000.0 0.78 781786.0 218000.0 1.08 1.3159 0.9877 1972735 ChemDiv1_005069 Cc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G10 compound treatment 696384.0 122000.0 0.55 719454.0 155000.0 0.77 0.9308 0.9861 1972736 ChemDiv1_005070 COc1ccccc1C2CC(=NN2C(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G11 compound treatment 747677.0 174000.0 0.78 759759.0 196000.0 0.97 1.2344 0.994 1972737 ChemDiv1_005071 [O-][N+](=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G12 compound treatment 682033.0 108000.0 0.48 725672.0 161000.0 0.8 0.9072 0.9708 1972738 ChemDiv1_005072 CN1CCN(CC(=O)N2N=C(CC2c3ccccc3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G13 compound treatment 747932.0 174000.0 0.78 748350.0 184000.0 0.91 1.1952 0.9969 1456998 ChemDiv1_005073 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G14 compound treatment 726929.0 153000.0 0.68 727390.0 163000.0 0.81 1.0553 0.9965 1639444 ChemDiv1_005074 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G15 compound treatment 723886.0 150000.0 0.67 736007.0 172000.0 0.85 1.0759 0.993 1268689 ChemDiv1_005075 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G16 compound treatment 709253.0 135000.0 0.6 738589.0 174000.0 0.86 1.0386 0.9848 1972739 ChemDiv1_005076 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G17 compound treatment 720744.0 147000.0 0.66 747249.0 183000.0 0.91 1.1053 0.9874 1226788 ChemDiv1_005077 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G18 compound treatment 704678.0 131000.0 0.58 706453.0 142000.0 0.7 0.9115 0.9957 1972740 ChemDiv1_005078 Brc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccco4)C(=O)c5ccco5)c(c6ccccc6)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G19 compound treatment 706841.0 133000.0 0.59 678889.0 115000.0 0.57 0.8218 0.9998 1139032 ChemDiv1_005079 COC(=O)C1=C(C)Nc2nnnn2C1c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G20 compound treatment 651538.0 77400.0 0.35 669059.0 105000.0 0.52 0.6124 0.9806 1972741 ChemDiv1_005080 CC(=O)C1=C(C)Nc2ncnn2C1c3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G21 compound treatment 683627.0 110000.0 0.49 659338.0 95100.0 0.47 0.6799 0.9998 1274882 ChemDiv1_005081 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G22 compound treatment 642675.0 68500.0 0.31 702810.0 139000.0 0.69 0.7025 0.9341 1518613 ChemDiv1_005082 CC1=C(C(c2ccc(O)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G23 mock treatment 642073.0 67900.0 0.3 696166.0 132000.0 0.65 0.6773 0.9394 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 G24 mock treatment 213931.0 -360000.0 -1.61 303681.0 -261000.0 -1.29 -2.0527 -0.9939 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H01 compound treatment 618492.0 44400.0 0.2 607414.0 43200.0 0.21 0.2918 0.9993 1585954 ChemDiv1_005083 CCOc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H02 compound treatment 623762.0 49600.0 0.22 638216.0 74000.0 0.37 0.4164 0.9712 1566677 ChemDiv1_005084 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4CCC(C)Cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H03 compound treatment 680709.0 107000.0 0.48 697102.0 133000.0 0.66 0.8029 0.9875 1278854 ChemDiv1_005085 CCOc1cc(ccc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H04 compound treatment 660643.0 86500.0 0.39 698728.0 135000.0 0.67 0.7451 0.9667 1566033 ChemDiv1_005086 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H05 compound treatment 695369.0 121000.0 0.54 739754.0 176000.0 0.87 0.9987 0.9742 1237224 ChemDiv1_005087 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H06 compound treatment 664689.0 90600.0 0.41 721715.0 158000.0 0.78 0.8384 0.9535 1136575 ChemDiv1_005088 CCOC(=O)C(C)Oc1ccc2c(=O)c(c(C)oc2c1)c3ccc4OCCCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H07 compound treatment 723230.0 149000.0 0.67 749502.0 185000.0 0.92 1.1211 0.9877 1608019 ChemDiv1_005089 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H08 compound treatment 708794.0 135000.0 0.6 702334.0 138000.0 0.68 0.9101 0.998 1972742 ChemDiv1_005090 COc1ccc(COCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H09 compound treatment 710731.0 137000.0 0.61 752611.0 188000.0 0.93 1.0924 0.979 1972743 ChemDiv1_005091 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCc7ccccc67 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H10 compound treatment 736637.0 163000.0 0.73 736457.0 172000.0 0.85 1.1178 0.9968 1972744 ChemDiv1_005092 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H11 compound treatment 702344.0 128000.0 0.57 744039.0 180000.0 0.89 1.0358 0.9774 1658546 ChemDiv1_005093 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H12 compound treatment 712315.0 138000.0 0.62 760927.0 197000.0 0.97 1.1265 0.9759 1972745 ChemDiv1_005094 CCOC(=O)CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H13 compound treatment 696377.0 122000.0 0.55 748942.0 185000.0 0.92 1.0341 0.9698 1924682 ChemDiv1_005095 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H14 compound treatment 717517.0 143000.0 0.64 771225.0 207000.0 1.03 1.1791 0.9745 1972746 ChemDiv1_005096 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CCCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H15 compound treatment 713338.0 139000.0 0.62 759561.0 195000.0 0.97 1.125 0.9773 1438246 ChemDiv1_005097 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccccc3Cl)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H16 compound treatment 663323.0 89200.0 0.4 766245.0 202000.0 1.0 0.9901 0.9188 1972747 ChemDiv1_005098 Cc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H17 compound treatment 719836.0 146000.0 0.65 758379.0 194000.0 0.96 1.1414 0.9821 1972748 ChemDiv1_005099 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(Cc5ccc(cc5)N6C(=O)C7C8CC(C=C8)C7C6=O)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H18 compound treatment 674942.0 101000.0 0.45 742613.0 178000.0 0.88 0.9441 0.9513 1702817 ChemDiv1_005100 COc1ccc(OCC(O)Cn2c(NCc3ccco3)nc4n(C)c(=O)n(C)c(=O)c24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H19 compound treatment 709847.0 136000.0 0.61 710940.0 147000.0 0.73 0.9436 0.996 1336807 ChemDiv1_005101 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H20 compound treatment 671093.0 97000.0 0.43 674721.0 111000.0 0.55 0.6941 0.9934 1343040 ChemDiv1_005102 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCN(C)CC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H21 compound treatment 665199.0 91100.0 0.41 722055.0 158000.0 0.78 0.8412 0.9539 1345782 ChemDiv1_005103 COc1cc(OC)cc(c1)C(=O)Nc2nc3ccccc3c4nc5ccccc5n24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H22 compound treatment 636721.0 62600.0 0.28 686932.0 123000.0 0.61 0.6281 0.9381 1184639 ChemDiv1_005104 C(Cn1c2ccccc2c3nc4ccccc4nc13)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H23 mock treatment 634114.0 60000.0 0.27 666388.0 102000.0 0.51 0.5478 0.956 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 H24 mock treatment 633980.0 59900.0 0.27 525290.0 -38900.0 -0.19 0.0532 0.1611 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I01 compound treatment 604286.0 30200.0 0.14 593930.0 29700.0 0.15 0.1996 0.9991 1972749 ChemDiv1_005105 COC(=O)c1ccc(NS(=O)(=O)c2cccc3C(=O)c4ccccc4C(=O)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I02 compound treatment 639760.0 65600.0 0.29 619855.0 55700.0 0.28 0.4027 0.9995 1407374 ChemDiv1_005106 COc1ccc(cc1OC)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I03 compound treatment 684709.0 111000.0 0.5 683691.0 119000.0 0.59 0.7686 0.996 1473917 ChemDiv1_005107 Cn1c(=O)n(C)c2nc(N3CCCCCC3)n(CC(O)COc4ccc(Cl)cc4)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I04 compound treatment 688796.0 115000.0 0.51 684709.0 121000.0 0.6 0.7851 0.9972 1734725 ChemDiv1_005108 CC1=C(C(c2ccc(Cl)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I05 compound treatment 702723.0 129000.0 0.58 695579.0 131000.0 0.65 0.8673 0.9981 1972750 ChemDiv1_005109 Cc1ccc(cc1)C2=NN(C(Cc3cc4cccc(C)c4[nH]c3=O)C2)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I06 compound treatment 650567.0 76400.0 0.34 676903.0 113000.0 0.56 0.6368 0.9724 1620598 ChemDiv1_005110 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I07 compound treatment 707961.0 134000.0 0.6 724975.0 161000.0 0.8 0.9868 0.9901 1972751 ChemDiv1_005111 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4cccs4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I08 compound treatment 684020.0 110000.0 0.49 695213.0 131000.0 0.65 0.8068 0.9907 1594581 ChemDiv1_005112 Cc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I09 compound treatment 722764.0 149000.0 0.67 739363.0 175000.0 0.87 1.0841 0.9914 1582217 ChemDiv1_005113 COc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccc(C)cc4)c5ccccc5)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I10 compound treatment 702907.0 129000.0 0.58 728125.0 164000.0 0.81 0.9818 0.9859 1481630 ChemDiv1_005114 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I11 compound treatment 687779.0 114000.0 0.51 740072.0 176000.0 0.87 0.9758 0.9672 1251440 ChemDiv1_005115 O=C(Nc1nc2CCCCc2s1)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc5C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I12 compound treatment 666816.0 92700.0 0.41 716250.0 152000.0 0.75 0.826 0.9605 1972752 ChemDiv1_005116 COc1ccccc1C2CC(=NN2C(=O)CN3CCCC3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I13 compound treatment 742288.0 168000.0 0.75 774980.0 211000.0 1.04 1.2706 0.9871 1283308 ChemDiv1_005117 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I14 compound treatment 697273.0 123000.0 0.55 751182.0 187000.0 0.93 1.0448 0.9693 1657584 ChemDiv1_005118 CC(=O)Nc1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I15 compound treatment 727955.0 154000.0 0.69 761726.0 198000.0 0.98 1.1788 0.9852 1484528 ChemDiv1_005119 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I16 compound treatment 698444.0 124000.0 0.56 702237.0 138000.0 0.68 0.877 0.9948 1972753 ChemDiv1_005120 Cc1ccc(o1)c2csc(NC(=O)c3cc(nc4ccccc34)c5cccs5)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I17 compound treatment 742208.0 168000.0 0.75 724919.0 161000.0 0.8 1.095 0.9996 1621567 ChemDiv1_005121 CC1=C(C(c2ccccc2Cl)n3ncnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I18 compound treatment 687240.0 113000.0 0.51 730950.0 167000.0 0.83 0.9422 0.9724 1605536 ChemDiv1_005122 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I19 compound treatment 672135.0 98000.0 0.44 698971.0 135000.0 0.67 0.7823 0.9793 1874354 ChemDiv1_005123 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I20 compound treatment 682153.0 108000.0 0.48 651753.0 87600.0 0.43 0.6486 0.9985 1972754 ChemDiv1_005124 CC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I21 compound treatment 696790.0 123000.0 0.55 701920.0 138000.0 0.68 0.8707 0.9942 1736427 ChemDiv1_005125 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I22 compound treatment 668226.0 94100.0 0.42 684850.0 121000.0 0.6 0.7205 0.9853 1199312 ChemDiv1_005126 COc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I23 mock treatment 649866.0 75700.0 0.34 707826.0 144000.0 0.71 0.7429 0.9425 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 I24 mock treatment 161492.0 -413000.0 -1.85 275865.0 -288000.0 -1.43 -2.3161 -0.9919 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J01 compound treatment 623705.0 49600.0 0.22 598736.0 34500.0 0.17 0.2779 0.9917 1603355 ChemDiv1_005127 CCOc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4ncnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J02 compound treatment 648708.0 74600.0 0.33 644005.0 79800.0 0.4 0.5156 0.9965 1373732 ChemDiv1_005128 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccc(C)cc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J03 compound treatment 662544.0 88400.0 0.4 668244.0 104000.0 0.52 0.6443 0.9915 1972755 ChemDiv1_005129 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4cc(Br)ccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J04 compound treatment 628561.0 54400.0 0.24 708654.0 144000.0 0.72 0.6783 0.8973 1361775 ChemDiv1_005130 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J05 compound treatment 699453.0 125000.0 0.56 730950.0 167000.0 0.83 0.9808 0.9822 1598839 ChemDiv1_005131 Cc1ccccc1n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J06 compound treatment 684748.0 111000.0 0.5 698778.0 135000.0 0.67 0.8216 0.9893 1972756 ChemDiv1_005132 COc1cccc(OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J07 compound treatment 694298.0 120000.0 0.54 716197.0 152000.0 0.75 0.9128 0.9864 1163398 ChemDiv1_005133 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J08 compound treatment 706583.0 132000.0 0.59 713132.0 149000.0 0.74 0.941 0.9941 1972757 ChemDiv1_005134 OC(COCC1COc2ccccc2O1)CN3CCC(CN4C(=O)c5cccc6cccc(C4=O)c56)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J09 compound treatment 719352.0 145000.0 0.65 750515.0 186000.0 0.92 1.1123 0.9853 1342219 ChemDiv1_005135 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4nc(SC)sc4c3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J10 compound treatment 694358.0 120000.0 0.54 752423.0 188000.0 0.93 1.0399 0.9659 1972758 ChemDiv1_005136 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC5)S(=O)(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J11 compound treatment 659415.0 85300.0 0.38 662635.0 98400.0 0.49 0.6148 0.9927 1173897 ChemDiv1_005137 CCOC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c3cccc(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J12 compound treatment 674518.0 100000.0 0.45 713385.0 149000.0 0.74 0.8404 0.9716 1972759 ChemDiv1_005138 O=C(CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCc6cccnc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J13 compound treatment 719739.0 146000.0 0.65 745263.0 181000.0 0.9 1.0952 0.9877 1924582 ChemDiv1_005139 O=C1N(CC2CCN(CC2)S(=O)(=O)c3cccc4cccnc34)C(=O)c5cccc6cccc1c56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J14 compound treatment 697137.0 123000.0 0.55 754123.0 190000.0 0.94 1.0547 0.9674 1972760 ChemDiv1_005140 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J15 compound treatment 712563.0 138000.0 0.62 770652.0 206000.0 1.02 1.1614 0.9712 1388128 ChemDiv1_005141 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCc3ccccc3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J16 compound treatment 692907.0 119000.0 0.53 729558.0 165000.0 0.82 0.9552 0.9781 1972761 ChemDiv1_005142 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J17 compound treatment 718469.0 144000.0 0.65 755925.0 192000.0 0.95 1.1285 0.9824 1972762 ChemDiv1_005143 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)S(=O)(=O)c5ccc(cc5)N6C(=O)C7C8CC(C=C8)C7C6=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J18 compound treatment 680522.0 106000.0 0.48 732799.0 169000.0 0.84 0.9274 0.9645 1972763 ChemDiv1_005144 CN(C)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J19 compound treatment 665542.0 91400.0 0.41 729960.0 166000.0 0.82 0.87 0.9483 1532629 ChemDiv1_005145 O=C(Nc1nc2c(cc3CCc4cccc2c43)s1)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J20 compound treatment 619516.0 45400.0 0.2 733417.0 169000.0 0.84 0.7364 0.8538 1498601 ChemDiv1_005146 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCOCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J21 compound treatment 666402.0 92300.0 0.41 742934.0 179000.0 0.89 0.9182 0.9397 1468534 ChemDiv1_005147 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)c4ccc(cc4)S(=O)(=O)N5CCCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J22 compound treatment 636683.0 62600.0 0.28 684194.0 120000.0 0.59 0.6183 0.941 1244709 ChemDiv1_005148 Clc1ccccc1Cn2c3ccccc3c4nc5ccccc5nc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J23 mock treatment 638051.0 63900.0 0.29 691769.0 128000.0 0.63 0.6492 0.9358 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 J24 mock treatment 193873.0 -380000.0 -1.7 529624.0 -34600.0 -0.17 -1.3247 -0.7743 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K01 compound treatment 611510.0 37400.0 0.17 584121.0 19900.0 0.1 0.1881 0.9683 1705922 ChemDiv1_005149 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC(C)(C)C)c3ccc(Cl)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K02 compound treatment 647245.0 73100.0 0.33 619457.0 55300.0 0.27 0.425 0.9961 1118186 ChemDiv1_005150 COc1ccc(OC)c(c1)C2C(=C(C)Nc3nnnn23)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K03 compound treatment 667149.0 93000.0 0.42 669574.0 105000.0 0.52 0.6636 0.9937 1484767 ChemDiv1_005151 CC(=O)N1N=C(CC1Cc2cc3cccc(C)c3nc2Cl)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K04 compound treatment 653581.0 79500.0 0.36 659181.0 95000.0 0.47 0.5842 0.9905 1632319 ChemDiv1_005152 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K05 compound treatment 672182.0 98100.0 0.44 696568.0 132000.0 0.66 0.7741 0.9809 1972764 ChemDiv1_005153 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccc(Br)cc4)c(=O)[nH]c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K06 compound treatment 684035.0 110000.0 0.49 697288.0 133000.0 0.66 0.8141 0.9896 1222959 ChemDiv1_005154 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K07 compound treatment 754182.0 180000.0 0.81 736153.0 172000.0 0.85 1.1723 0.9996 1972765 ChemDiv1_005155 Fc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K08 compound treatment 708232.0 134000.0 0.6 699954.0 136000.0 0.67 0.9 0.9984 1972766 ChemDiv1_005156 [O-][N+](=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K09 compound treatment 741682.0 168000.0 0.75 732710.0 169000.0 0.83 1.1206 0.9986 1372596 ChemDiv1_005157 Cc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K10 compound treatment 723582.0 149000.0 0.67 726913.0 163000.0 0.81 1.043 0.9957 1280204 ChemDiv1_005158 Clc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K11 compound treatment 733094.0 159000.0 0.71 717118.0 153000.0 0.76 1.0388 0.9995 1972767 ChemDiv1_005159 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K12 compound treatment 679238.0 105000.0 0.47 705791.0 142000.0 0.7 0.8287 0.9811 1972768 ChemDiv1_005160 Cc1ccc(Sc2c(nc3ccccn23)c4ccc(Br)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K13 compound treatment 721348.0 147000.0 0.66 727089.0 163000.0 0.81 1.0366 0.9949 1241843 ChemDiv1_005161 CC1=C(C(c2ccccc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K14 compound treatment 692186.0 118000.0 0.53 720836.0 157000.0 0.78 0.9224 0.9825 1972769 ChemDiv1_005162 O=C(Nc1nc(cs1)c2cc3ccccc3oc2=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K15 compound treatment 717848.0 144000.0 0.64 742687.0 178000.0 0.88 1.0802 0.9878 1874367 ChemDiv1_005163 CC1=C(C(c2cccc(c2)[N+](=O)[O-])n3ncnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K16 compound treatment 684233.0 110000.0 0.49 705502.0 141000.0 0.7 0.8435 0.9853 1150618 ChemDiv1_005164 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3c(ccc4ccccc34)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K17 compound treatment 695253.0 121000.0 0.54 725204.0 161000.0 0.8 0.9474 0.9823 1154289 ChemDiv1_005165 COc1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K18 compound treatment 682520.0 108000.0 0.49 695504.0 131000.0 0.65 0.8031 0.9896 1342192 ChemDiv1_005166 OC(=O)CCC(=O)N1N=C(CC1c2cccs2)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K19 compound treatment 708976.0 135000.0 0.6 707640.0 143000.0 0.71 0.9293 0.9967 1717539 ChemDiv1_005167 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(cc3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K20 compound treatment 671490.0 97400.0 0.44 706593.0 142000.0 0.71 0.807 0.9732 1408791 ChemDiv1_005168 COC(=O)C1=C(C)Nc2ncnn2C1c3ccc4ncccc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K21 compound treatment 686205.0 112000.0 0.5 727154.0 163000.0 0.81 0.9256 0.9738 1641304 ChemDiv1_005169 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cc(OC)ccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K22 compound treatment 626903.0 52800.0 0.24 707790.0 144000.0 0.71 0.67 0.8939 1212451 ChemDiv1_005170 CCOc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K23 mock treatment 648372.0 74200.0 0.33 703830.0 140000.0 0.69 0.7241 0.9436 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 K24 mock treatment 497889.0 -76200.0 -0.34 528258.0 -35900.0 -0.18 -0.3672 -0.954 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L01 compound treatment 597424.0 23300.0 0.1 608847.0 44700.0 0.22 0.2302 0.9411 1363123 ChemDiv1_005171 CC1=C(C(c2ccc3OCOc3c2)n4ncnc4N1)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L02 compound treatment 614885.0 40800.0 0.18 641829.0 77600.0 0.38 0.401 0.9419 1251416 ChemDiv1_005172 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(NC(=O)C)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L03 compound treatment 662817.0 88700.0 0.4 680839.0 117000.0 0.58 0.6893 0.9832 1972770 ChemDiv1_005173 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L04 compound treatment 646170.0 72000.0 0.32 692758.0 129000.0 0.64 0.6784 0.9503 1574019 ChemDiv1_005174 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L05 compound treatment 670720.0 96600.0 0.43 711249.0 147000.0 0.73 0.8209 0.969 1330420 ChemDiv1_005175 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L06 compound treatment 678794.0 105000.0 0.47 689284.0 125000.0 0.62 0.7695 0.9905 1972771 ChemDiv1_005176 COc1cccc(OCC(O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L07 compound treatment 680936.0 107000.0 0.48 725842.0 162000.0 0.8 0.9043 0.9696 1972772 ChemDiv1_005177 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L08 compound treatment 685770.0 112000.0 0.5 697062.0 133000.0 0.66 0.8188 0.9908 1972773 ChemDiv1_005178 OC(COc1ccc(F)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L09 compound treatment 674489.0 100000.0 0.45 739075.0 175000.0 0.87 0.9303 0.9532 1416651 ChemDiv1_005179 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5)sc3c2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L10 compound treatment 677140.0 103000.0 0.46 675699.0 112000.0 0.55 0.7166 0.996 1972774 ChemDiv1_005180 Fc1ccc(cc1)N2CCN(CC2)C(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L11 compound treatment 701410.0 127000.0 0.57 731378.0 167000.0 0.83 0.9885 0.9833 1925016 ChemDiv1_005181 COc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L12 compound treatment 701348.0 127000.0 0.57 723154.0 159000.0 0.79 0.9595 0.9873 1972775 ChemDiv1_005182 O=C(CSc1nnc(CN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5)NCCCN6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L13 compound treatment 681392.0 107000.0 0.48 729579.0 165000.0 0.82 0.9188 0.9676 1972776 ChemDiv1_005183 O=C(N1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1)c5ccc(cc5)S(=O)(=O)N6CCCCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L14 compound treatment 660851.0 86700.0 0.39 741318.0 177000.0 0.88 0.8949 0.9327 1972777 ChemDiv1_005184 O=C(CSc1nnc2sc3ccccc3n12)NC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L15 compound treatment 674338.0 100000.0 0.45 762757.0 199000.0 0.98 1.0127 0.9368 1301772 ChemDiv1_005185 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3cccc(Cl)c3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L16 compound treatment 704828.0 131000.0 0.59 739506.0 175000.0 0.87 1.0278 0.9815 1205223 ChemDiv1_005186 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCOCC4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L17 compound treatment 680728.0 107000.0 0.48 766684.0 202000.0 1.0 1.0467 0.9423 1972778 ChemDiv1_005187 OC(=O)C(Cc1c[nH]c2ccccc12)N3C(=O)C4C(C5c6ccccc6C4c7ccccc57)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L18 compound treatment 672421.0 98300.0 0.44 712152.0 148000.0 0.73 0.8294 0.9702 1972779 ChemDiv1_005188 CCN(CC)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L19 compound treatment 616657.0 42500.0 0.19 701048.0 137000.0 0.68 0.614 0.8719 1347464 ChemDiv1_005189 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccccc3c4nc5ccccc5n24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L20 compound treatment 673562.0 99400.0 0.45 734462.0 170000.0 0.84 0.9112 0.9554 1633496 ChemDiv1_005190 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N4CCCCCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L21 compound treatment 661935.0 87800.0 0.39 750019.0 186000.0 0.92 0.9289 0.928 1518368 ChemDiv1_005191 CCOC(=O)Cc1csc(NC(=S)NC(=O)c2sc3ccccc3c2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L22 compound treatment 605136.0 31000.0 0.14 709555.0 145000.0 0.72 0.6073 0.8282 1518130 ChemDiv1_005192 Cn1c(SCC(=O)NCc2ccccn2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L23 mock treatment 632227.0 58100.0 0.26 699853.0 136000.0 0.67 0.6591 0.9147 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 L24 mock treatment 544374.0 -29800.0 -0.13 523801.0 -40400.0 -0.2 -0.2357 -0.9804 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M01 compound treatment 618361.0 44200.0 0.2 598444.0 34200.0 0.17 0.26 0.997 1156178 ChemDiv1_005193 CN1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3n2CC(O)COc4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M02 compound treatment 631012.0 56900.0 0.25 608513.0 44300.0 0.22 0.3353 0.9973 1586133 ChemDiv1_005194 CC1=C(C(c2ccc(Br)cc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M03 compound treatment 699168.0 125000.0 0.56 693928.0 130000.0 0.64 0.8502 0.9976 1708821 ChemDiv1_005195 Cc1cccc2cc(CC3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M04 compound treatment 675155.0 101000.0 0.45 678555.0 114000.0 0.57 0.7204 0.9938 1228364 ChemDiv1_005196 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M05 compound treatment 1263369.0 689000.0 3.09 1112994.0 549000.0 2.72 4.104 0.998 1730659 ChemDiv1_005197 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M06 compound treatment 704549.0 130000.0 0.58 653856.0 89700.0 0.44 0.7269 0.9909 1276304 ChemDiv1_005198 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M07 compound treatment 729866.0 156000.0 0.7 712684.0 148000.0 0.74 1.0131 0.9996 1244056 ChemDiv1_005199 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c(Cl)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M08 compound treatment 704642.0 131000.0 0.58 670701.0 107000.0 0.53 0.7862 0.9987 1219328 ChemDiv1_005200 CC1CCc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M09 compound treatment 719262.0 145000.0 0.65 688776.0 125000.0 0.62 0.8958 0.9997 1135249 ChemDiv1_005201 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4ccc(Br)cc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M10 compound treatment 779827.0 206000.0 0.92 826362.0 262000.0 1.3 1.5694 0.9858 1972780 ChemDiv1_005202 Brc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M11 compound treatment 722012.0 148000.0 0.66 736536.0 172000.0 0.85 1.0718 0.9921 1972781 ChemDiv1_005203 COC(=O)c1ccc(cc1)C(=O)Nc2nc(c3cccs3)c(s2)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M12 compound treatment 709613.0 135000.0 0.61 708977.0 145000.0 0.72 0.936 0.9965 1639426 ChemDiv1_005204 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc6C5)sc32)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M13 compound treatment 728973.0 155000.0 0.69 718479.0 154000.0 0.76 1.0306 0.9988 1874360 ChemDiv1_005205 CC1=C(C(c2ccc(cc2)[N+](=O)[O-])n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M14 compound treatment 698894.0 125000.0 0.56 706898.0 143000.0 0.71 0.8948 0.9932 1972782 ChemDiv1_005206 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M15 compound treatment 706143.0 132000.0 0.59 733311.0 169000.0 0.84 1.0103 0.9854 1686726 ChemDiv1_005207 CC1=C(C(c2ccccc2Cl)n3ncnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M16 compound treatment 682447.0 108000.0 0.48 711260.0 147000.0 0.73 0.858 0.9804 1194673 ChemDiv1_005208 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3CCCc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M17 compound treatment 688792.0 115000.0 0.51 737577.0 173000.0 0.86 0.9703 0.9697 1485835 ChemDiv1_005209 COc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M18 compound treatment 683153.0 109000.0 0.49 714616.0 150000.0 0.75 0.872 0.9789 1531488 ChemDiv1_005210 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M19 compound treatment 711145.0 137000.0 0.61 732442.0 168000.0 0.83 1.023 0.9886 1313723 ChemDiv1_005211 COC(=O)C1=C(C)Nc2nnnn2C1c3cc(OC)ccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M20 compound treatment 632228.0 58100.0 0.26 699869.0 136000.0 0.67 0.6592 0.9146 1455629 ChemDiv1_005212 COC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M21 compound treatment 664497.0 90400.0 0.4 725798.0 162000.0 0.8 0.8521 0.95 1727572 ChemDiv1_005213 CCOC(=O)C1=C(C)Nc2nnnn2C1c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M22 compound treatment 628533.0 54400.0 0.24 678488.0 114000.0 0.57 0.5726 0.929 1686374 ChemDiv1_005214 CCOc1cc(ccc1OC(=O)c2ccccc2)C3C(=C(C)Nc4nnnn34)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M23 mock treatment 629829.0 55700.0 0.25 679525.0 115000.0 0.57 0.5803 0.9309 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 M24 mock treatment 525906.0 -48200.0 -0.22 406967.0 -157000.0 -0.78 -0.7034 -0.8703 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N01 compound treatment 591592.0 17500.0 0.08 602182.0 38000.0 0.19 0.1883 0.9243 1407895 ChemDiv1_005215 CC1=C(C(c2ccccn2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N02 compound treatment 611688.0 37600.0 0.17 644870.0 80700.0 0.4 0.4015 0.926 1259554 ChemDiv1_005216 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4c(C)cc(C)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N03 compound treatment 638905.0 64800.0 0.29 679075.0 115000.0 0.57 0.6074 0.9511 1972783 ChemDiv1_005217 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N04 compound treatment 626171.0 52000.0 0.23 671088.0 107000.0 0.53 0.5392 0.932 1448129 ChemDiv1_005218 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5[nH]4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N05 compound treatment 676661.0 103000.0 0.46 707495.0 143000.0 0.71 0.8265 0.9777 1972784 ChemDiv1_005219 [O-][N+](=O)c1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N06 compound treatment 613829.0 39700.0 0.18 635940.0 71700.0 0.36 0.377 0.9487 1972785 ChemDiv1_005220 Cc1ccc(OCC(O)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N07 compound treatment 691367.0 117000.0 0.52 733478.0 169000.0 0.84 0.9641 0.9745 1162532 ChemDiv1_005221 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(C)cc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N08 compound treatment 624865.0 50700.0 0.23 643018.0 78800.0 0.39 0.4367 0.9668 1972786 ChemDiv1_005222 OC(COc1ccccc1CC=C)CN2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N09 compound treatment 687774.0 114000.0 0.51 699254.0 135000.0 0.67 0.8328 0.9909 1635437 ChemDiv1_005223 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCC5)sc3c2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N10 compound treatment 660132.0 86000.0 0.38 709200.0 145000.0 0.72 0.7802 0.9573 1547630 ChemDiv1_005224 COc1ccc(cc1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N11 compound treatment 668355.0 94200.0 0.42 697147.0 133000.0 0.66 0.764 0.9768 1925128 ChemDiv1_005225 O=C1N(CC2CCN(CC2)S(=O)(=O)c3cccs3)C(=O)c4cccc5cccc1c45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N12 compound treatment 651269.0 77100.0 0.35 720362.0 156000.0 0.77 0.7912 0.9339 1972787 ChemDiv1_005226 COC(=O)c1ccc(CN2CCN(CCN3C(=O)C4C5CC(C=C5)C4C3=O)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N13 compound treatment 677221.0 103000.0 0.46 711659.0 147000.0 0.73 0.8429 0.9755 1925203 ChemDiv1_005227 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)c4ccc(NS(=O)(=O)c5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N14 compound treatment 656490.0 82400.0 0.37 701823.0 138000.0 0.68 0.7428 0.9583 1972788 ChemDiv1_005228 Cc1cc(NC(=O)c2ccc3OCCOc3c2)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N15 compound treatment 682646.0 109000.0 0.49 751328.0 187000.0 0.93 0.999 0.9545 1972789 ChemDiv1_005229 CCOC(=O)c1c(oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N16 compound treatment 648433.0 74300.0 0.33 719674.0 155000.0 0.77 0.7798 0.9295 1972790 ChemDiv1_005230 CN(C)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N17 compound treatment 654406.0 80300.0 0.36 734926.0 171000.0 0.85 0.8522 0.9273 1265983 ChemDiv1_005231 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccc(cc4)S(=O)(=O)Nc5nccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N18 compound treatment 644643.0 70500.0 0.32 721855.0 158000.0 0.78 0.7755 0.9206 1568399 ChemDiv1_005232 Cn1c(=O)n(C)c2nc(S)n(Cc3ccc(F)cc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N19 compound treatment 663552.0 89400.0 0.4 727423.0 163000.0 0.81 0.8548 0.9474 1594393 ChemDiv1_005233 CC1(CC2CC(C)(C)C1)CN2S(=O)(=O)c3ccc(cc3)C(=O)Nc4cccc(c4)c5nc6ccccc6[nH]5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N20 compound treatment 630368.0 56200.0 0.25 677921.0 114000.0 0.56 0.5764 0.9341 1972791 ChemDiv1_005234 Cc1ccccc1OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)n(C)c(=O)c24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N21 compound treatment 623907.0 49800.0 0.22 731299.0 167000.0 0.83 0.7429 0.8666 1448163 ChemDiv1_005235 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(OC)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N22 compound treatment 617601.0 43500.0 0.19 696287.0 132000.0 0.65 0.6003 0.8793 1512613 ChemDiv1_005236 Cn1c(SCc2ccc(cc2)C(=O)NCCO)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N23 mock treatment 598072.0 23900.0 0.11 671420.0 107000.0 0.53 0.4514 0.833 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 N24 mock treatment 573002.0 -1120.0 -0.01 399879.0 -164000.0 -0.81 -0.5791 -0.7115 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O01 compound treatment 612263.0 38100.0 0.17 590423.0 26200.0 0.13 0.2126 0.9909 1426253 ChemDiv1_005237 Cc1ccccc1OCC(O)Cn2c(NCc3ccccc3)nc4n(C)c(=O)n(C)c(=O)c24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O02 compound treatment 603855.0 29700.0 0.13 607387.0 43200.0 0.21 0.2454 0.9739 1628501 ChemDiv1_005238 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O03 compound treatment 638829.0 64700.0 0.29 653679.0 89500.0 0.44 0.5183 0.9787 1351269 ChemDiv1_005239 CC(=O)N1N=C(CC1Cc2cc3cccc(C)c3[nH]c2=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O04 compound treatment 658789.0 84700.0 0.38 684239.0 120000.0 0.59 0.6885 0.9763 1263263 ChemDiv1_005240 CC1=C(C(c2ccc(OCc3ccccc3)cc2)n4nnnc4N1)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O05 compound treatment 684554.0 110000.0 0.49 701624.0 137000.0 0.68 0.8309 0.9876 1972792 ChemDiv1_005241 COc1cccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O06 compound treatment 661930.0 87800.0 0.39 655602.0 91400.0 0.45 0.5981 0.9975 1537433 ChemDiv1_005242 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O07 compound treatment 678779.0 105000.0 0.47 657712.0 93500.0 0.46 0.6588 1.0 1432170 ChemDiv1_005243 Cc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c(Cl)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O08 compound treatment 686077.0 112000.0 0.5 644062.0 79900.0 0.4 0.6341 0.9932 1313363 ChemDiv1_005244 Cc1cccc2sc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O09 compound treatment 708201.0 134000.0 0.6 695579.0 131000.0 0.65 0.8846 0.9992 1972793 ChemDiv1_005245 Brc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O10 compound treatment 707179.0 133000.0 0.6 715533.0 151000.0 0.75 0.9513 0.9935 1675957 ChemDiv1_005246 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O11 compound treatment 654548.0 80400.0 0.36 679908.0 116000.0 0.57 0.6599 0.9749 1972794 ChemDiv1_005247 Nc1ncnc(Sc2nc3ccccc3o2)c1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O12 compound treatment 655055.0 80900.0 0.36 657689.0 93500.0 0.46 0.5837 0.9926 1553500 ChemDiv1_005248 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56)sc32)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O13 compound treatment 692007.0 118000.0 0.53 693679.0 129000.0 0.64 0.8267 0.9953 1200470 ChemDiv1_005249 CC1=C(C(c2ccc(Cl)cc2)n3ncnc3N1)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O14 compound treatment 663556.0 89400.0 0.4 651982.0 87800.0 0.43 0.5906 0.9991 1666456 ChemDiv1_005250 O=C(Nc1ccccc1c2nc3ccccc3[nH]2)c4ccc(cc4)S(=O)(=O)N5CCc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O15 compound treatment 687167.0 113000.0 0.51 711046.0 147000.0 0.73 0.8722 0.9843 1159530 ChemDiv1_005251 CN(C)c1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O16 compound treatment 629558.0 55400.0 0.25 669212.0 105000.0 0.52 0.5433 0.9426 1972795 ChemDiv1_005252 [O-][N+](=O)c1cccc(c1)C2CC(=NN2C(=O)c3cccs3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O17 compound treatment 672280.0 98200.0 0.44 697868.0 134000.0 0.66 0.7789 0.9801 1198680 ChemDiv1_005253 CN(C)c1ccc(cc1)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O18 compound treatment 647520.0 73400.0 0.33 700325.0 136000.0 0.67 0.7092 0.9454 1524008 ChemDiv1_005254 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O19 compound treatment 659505.0 85400.0 0.38 690072.0 126000.0 0.62 0.7112 0.9724 1673712 ChemDiv1_005255 COC(=O)C1=C(C)Nc2nnnn2C1c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O20 compound treatment 627507.0 53400.0 0.24 639883.0 75700.0 0.37 0.4341 0.9763 1216323 ChemDiv1_005256 CCOC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O21 compound treatment 644229.0 70100.0 0.31 686991.0 123000.0 0.61 0.652 0.9526 1226642 ChemDiv1_005257 CCOC(=O)C1=C(C)Nc2nnnn2C1c3ccc(OCc4ccccc4)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O22 compound treatment 583274.0 9150.0 0.04 676780.0 113000.0 0.56 0.4233 0.757 1340233 ChemDiv1_005258 CC1=C(C(c2ccc3OCOc3c2)n4nnnc4N1)C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O23 mock treatment 611491.0 37400.0 0.17 648111.0 83900.0 0.42 0.4122 0.9199 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 O24 mock treatment 435735.0 -138000.0 -0.62 423612.0 -141000.0 -0.7 -0.9305 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P01 compound treatment 548424.0 -25700.0 -0.12 574398.0 10200.0 0.05 -0.0456 -0.363 1224440 ChemDiv1_005259 CC1=C(C(c2ccc(O)cc2)n3ncnc3N1)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P02 compound treatment 582502.0 8380.0 0.04 585852.0 21700.0 0.11 0.1024 0.9008 1519181 ChemDiv1_005260 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc4sc(C)nc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P03 compound treatment 583944.0 9820.0 0.04 601701.0 37500.0 0.19 0.1625 0.8509 1972796 ChemDiv1_005261 Cc1onc(c1C(=O)Nc2c3CSCc3nn2c4ccc(cc4)[N+](=O)[O-])c5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P04 compound treatment 590538.0 16400.0 0.07 611975.0 47800.0 0.24 0.2193 0.8849 1238521 ChemDiv1_005262 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5nc(SC)sc5c4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P05 compound treatment 599682.0 25600.0 0.11 623830.0 59600.0 0.3 0.2898 0.9147 1409682 ChemDiv1_005263 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P06 compound treatment 616772.0 42600.0 0.19 616997.0 52800.0 0.26 0.3199 0.988 1972797 ChemDiv1_005264 OC(COCc1ccc(Cl)cc1)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P07 compound treatment 630450.0 56300.0 0.25 625566.0 61400.0 0.3 0.3933 0.9957 1179247 ChemDiv1_005265 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4cc(C)cc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P08 compound treatment 616973.0 42800.0 0.19 625043.0 60800.0 0.3 0.3488 0.9762 1972798 ChemDiv1_005266 COc1ccc(OCC(O)CN2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P09 compound treatment 610898.0 36800.0 0.16 619000.0 54800.0 0.27 0.3084 0.9713 1166468 ChemDiv1_005267 CSc1nc2ccc3nc(NC(=O)c4ccc(cc4)S(=O)(=O)N5CC(C)OC(C)C5)sc3c2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P10 compound treatment 632576.0 58400.0 0.26 617198.0 53000.0 0.26 0.3707 1.0 1972799 ChemDiv1_005268 Clc1ccc(OCC(=O)N2CCN(CCN3C(=O)c4cccc5cccc(C3=O)c45)CC2)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P11 compound treatment 596250.0 22100.0 0.1 629883.0 65700.0 0.33 0.3001 0.8823 1924720 ChemDiv1_005269 Fc1ccc(cc1)S(=O)(=O)N2CCC(CN3C(=O)c4cccc5cccc(C3=O)c45)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P12 compound treatment 632633.0 58500.0 0.26 676016.0 112000.0 0.55 0.5769 0.9415 1736814 ChemDiv1_005270 COC(=O)c1ccc(CSc2nc3sc4CCCc4c3c(=O)n2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P13 compound treatment 631325.0 57200.0 0.26 635174.0 71000.0 0.35 0.4297 0.9879 1925272 ChemDiv1_005271 CCOC(=O)c1c(oc2cc(Br)c(OS(=O)(=O)C)cc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P14 compound treatment 616095.0 42000.0 0.19 632886.0 68700.0 0.34 0.3735 0.9608 1972800 ChemDiv1_005272 O=C(N1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1)C5(CC6CC7CC(C6)C5)C7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P15 compound treatment 596504.0 22400.0 0.1 628868.0 64700.0 0.32 0.2974 0.8859 1925045 ChemDiv1_005273 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)C(C)(C)C)cc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P16 compound treatment 602596.0 28500.0 0.13 652229.0 88000.0 0.44 0.3985 0.8771 1972801 ChemDiv1_005274 CCN(CC)CCNc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P17 compound treatment 604014.0 29900.0 0.13 648237.0 84000.0 0.42 0.389 0.8895 1972802 ChemDiv1_005275 C=CCn1c(CCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1SCC(=O)NCc5cccnc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P18 compound treatment 596320.0 22200.0 0.1 639417.0 75200.0 0.37 0.3337 0.8654 1431996 ChemDiv1_005276 COc1ccc(OCC(O)Cn2c(NCCN(C)C)nc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P19 compound treatment 593872.0 19700.0 0.09 631123.0 66900.0 0.33 0.2969 0.8654 1231993 ChemDiv1_005277 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P20 compound treatment 584783.0 10700.0 0.05 629291.0 65100.0 0.32 0.2618 0.803 1972803 ChemDiv1_005278 COc1ccc(OCC(O)Cn2c(NCCCn3ccnc3)nc4n(C)c(=O)n(C)c(=O)c24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P21 compound treatment 569022.0 -5100.0 -0.02 648280.0 84100.0 0.42 0.2784 0.6673 1464765 ChemDiv1_005279 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc(OCC)cc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P22 compound treatment 573766.0 -361.0 0.0 600197.0 36000.0 0.18 0.125 0.7007 1972804 ChemDiv1_005280 CCCCOC(=O)C1Cc2c([nH]c3ccccc23)C(C)N1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P23 mock treatment 571682.0 -2440.0 -0.01 625039.0 60800.0 0.3 0.2054 0.681 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.601 P24 mock treatment 422408.0 -152000.0 -0.68 435777.0 -128000.0 -0.64 -0.9301 -0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A01 compound treatment 568482.0 -22900.0 -0.1 548113.0 -29300.0 -0.15 -0.1751 -0.9853 1972805 ChemDiv1_005281 [O-][N+](=O)c1ccc2[nH]c(SCc3nc4ncccn4c3Br)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A02 compound treatment 561426.0 -29900.0 -0.13 547951.0 -29500.0 -0.15 -0.198 -0.9991 1293321 ChemDiv1_005282 Brc1ccc(cc1)c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A03 compound treatment 568301.0 -23000.0 -0.1 567318.0 -10100.0 -0.05 -0.1084 -0.945 1972806 ChemDiv1_005283 [O-][N+](=O)c1ccc2oc(SCc3nc4ccccn4c3Br)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A04 compound treatment 576481.0 -14900.0 -0.07 572516.0 -4920.0 -0.02 -0.0643 -0.9072 1320843 ChemDiv1_005284 CCN(CC)C(=O)c1sc(NC(=O)C(Sc2ccccc2)c3ccccc3)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A05 compound treatment 586244.0 -5100.0 -0.02 574330.0 -3110.0 -0.02 -0.027 -0.9816 1782529 ChemDiv1_005285 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4cccc(c4)[N+](=O)[O-])cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A06 compound treatment 619664.0 28300.0 0.13 613014.0 35600.0 0.18 0.2143 0.9869 1949890 ChemDiv1_005286 COc1ccc(cc1OC)c2cc(C(=O)Nc3cccc(c3)C(=O)C)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A07 compound treatment 631996.0 40700.0 0.18 613454.0 36000.0 0.18 0.2548 1.0 1972807 ChemDiv1_005287 [O-][N+](=O)c1cccc(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A08 compound treatment 638989.0 47600.0 0.21 618329.0 40900.0 0.2 0.2941 0.9997 1382679 ChemDiv1_005288 Cc1nc2sc3CCCc3c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A09 compound treatment 628692.0 37300.0 0.17 567947.0 -9490.0 -0.05 0.085 0.4893 1972808 ChemDiv1_005289 Clc1ccc(Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A10 compound treatment 653404.0 62100.0 0.28 651700.0 74300.0 0.37 0.4566 0.9904 1972809 ChemDiv1_005290 Brc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A11 compound treatment 635128.0 43800.0 0.2 632057.0 54600.0 0.27 0.3299 0.9875 1242730 ChemDiv1_005291 CCOc1cccc(c1)c2cc(C(=O)Nc3ccc4OCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A12 compound treatment 630376.0 39000.0 0.17 620161.0 42700.0 0.21 0.2732 0.9955 1477240 ChemDiv1_005292 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A13 compound treatment 624631.0 33300.0 0.15 645833.0 68400.0 0.34 0.345 0.9319 1972810 ChemDiv1_005293 Cc1onc(c1C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23)c5c(Cl)cccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A14 compound treatment 643387.0 52000.0 0.23 644095.0 66700.0 0.33 0.3982 0.9854 1391846 ChemDiv1_005294 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A15 compound treatment 676452.0 85100.0 0.38 647863.0 70400.0 0.35 0.5161 0.999 1473341 ChemDiv1_005295 COc1ccc(c(OC)c1)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A16 compound treatment 644599.0 53300.0 0.24 625299.0 47900.0 0.24 0.3362 1.0 1371826 ChemDiv1_005296 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A17 compound treatment 636914.0 45600.0 0.2 611460.0 34000.0 0.17 0.2634 0.9955 1607802 ChemDiv1_005297 Cc1ccc(cc1C)c2cc(C(=O)Nc3ccccc3C(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A18 compound treatment 639650.0 48300.0 0.22 612294.0 34900.0 0.17 0.275 0.9938 1670585 ChemDiv1_005298 CN(C)c1nc(nc(n1)N(CCOc2ccccc2)C#N)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A19 compound treatment 599246.0 7900.0 0.04 605329.0 27900.0 0.14 0.1227 0.8604 1342940 ChemDiv1_005299 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3sc4CC(CCc4c3C#N)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A20 compound treatment 593664.0 2320.0 0.01 564359.0 -13100.0 -0.06 -0.0385 -0.5862 1558173 ChemDiv1_005300 Cc1cc(Cl)ccc1OCC(=O)Nc2ncnc3sc4CCCCc4c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A21 compound treatment 607781.0 16400.0 0.07 600952.0 23500.0 0.12 0.1344 0.9755 1175527 ChemDiv1_005301 COc1ccc(cc1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A22 compound treatment 603221.0 11900.0 0.05 574435.0 -3000.0 -0.01 0.0271 0.4906 1140805 ChemDiv1_005302 O=C(Nc1cccc2cccnc12)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A23 mock treatment 590452.0 -891.0 0.0 543834.0 -33600.0 -0.17 -0.1205 -0.7238 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 A24 mock treatment 526008.0 -65300.0 -0.29 510200.0 -67200.0 -0.33 -0.4423 -0.9979 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B01 compound treatment 609097.0 17800.0 0.08 589834.0 12400.0 0.06 0.0996 0.9919 1334366 ChemDiv1_005303 NC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B02 compound treatment 635283.0 43900.0 0.2 608956.0 31500.0 0.16 0.2495 0.9935 1972811 ChemDiv1_005304 CC1CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc4N1C(=O)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B03 compound treatment 677640.0 86300.0 0.39 674697.0 97300.0 0.48 0.6138 0.994 1972812 ChemDiv1_005305 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)N)n42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B04 compound treatment 654126.0 62800.0 0.28 669882.0 92400.0 0.46 0.5226 0.9725 1727616 ChemDiv1_005306 CCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B05 compound treatment 702202.0 111000.0 0.5 699001.0 122000.0 0.6 0.7767 0.9954 1684723 ChemDiv1_005307 O=C(N1CCSC1c2ccc3CCc4cccc2c43)c5cc6ccccc6oc5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B06 compound treatment 675443.0 84100.0 0.38 686766.0 109000.0 0.54 0.6492 0.9842 1972813 ChemDiv1_005308 [O-][N+](=O)c1cccc(c1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B07 compound treatment 706437.0 115000.0 0.52 709633.0 132000.0 0.65 0.8274 0.993 1972814 ChemDiv1_005309 Cc1ccc(cc1S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B08 compound treatment 721721.0 130000.0 0.58 706153.0 129000.0 0.64 0.8636 0.999 1712803 ChemDiv1_005310 COc1ccc(cc1OC)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B09 compound treatment 703517.0 112000.0 0.5 730242.0 153000.0 0.76 0.8903 0.9801 1399782 ChemDiv1_005311 O=C(Nc1cccc(c1)c2cn3ccccc3n2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B10 compound treatment 694483.0 103000.0 0.46 714357.0 137000.0 0.68 0.8061 0.9824 1972815 ChemDiv1_005312 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(cc4)C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B11 compound treatment 703399.0 112000.0 0.5 743368.0 166000.0 0.82 0.9359 0.9719 1508646 ChemDiv1_005313 CCOc1ccc2nc(Nc3nc(O)c4ccccc4n3)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B12 compound treatment 662449.0 71100.0 0.32 721628.0 144000.0 0.71 0.7302 0.9337 1972816 ChemDiv1_005314 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B13 compound treatment 724729.0 133000.0 0.6 729205.0 152000.0 0.75 0.9538 0.9935 1135592 ChemDiv1_005315 CCCC(=O)N1C(C)CC(N(C(=O)c2ccccc2)c3ccc(F)cc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B14 compound treatment 721046.0 130000.0 0.58 719696.0 142000.0 0.7 0.9089 0.9954 1972817 ChemDiv1_005316 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B15 compound treatment 769159.0 178000.0 0.8 778631.0 201000.0 1.0 1.2676 0.9938 1940250 ChemDiv1_005317 FC(F)(F)c1ccc2Sc3ccccc3N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B16 compound treatment 719825.0 128000.0 0.58 711303.0 134000.0 0.66 0.8756 0.9975 1972818 ChemDiv1_005318 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccc(cc5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B17 compound treatment 750463.0 159000.0 0.71 753900.0 176000.0 0.87 1.1218 0.9948 1972819 ChemDiv1_005319 CC1(C)N(C(=O)c2sc3ccccc3c2Cl)c4ccccc4-c5c1ssc5=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B18 compound treatment 715183.0 124000.0 0.55 704565.0 127000.0 0.63 0.8373 0.998 1972820 ChemDiv1_005320 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5cccc(OC(=O)N6CCOCC6)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B19 compound treatment 716884.0 126000.0 0.56 755375.0 178000.0 0.88 1.0207 0.9764 1972821 ChemDiv1_005321 COc1ccc2nc(SCc3ccc(cc3)[N+](=O)[O-])nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B20 compound treatment 705575.0 114000.0 0.51 698819.0 121000.0 0.6 0.7868 0.9967 1972822 ChemDiv1_005322 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B21 compound treatment 713570.0 122000.0 0.55 724702.0 147000.0 0.73 0.9027 0.9899 1171320 ChemDiv1_005323 CC1CC(N(C(=O)c2ccc(F)cc2)c3ccccc3)c4ccccc4N1C(=O)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B22 compound treatment 685327.0 94000.0 0.42 668082.0 90600.0 0.45 0.615 0.9995 1712115 ChemDiv1_005324 Cc1ccc(cc1C)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B23 mock treatment 683472.0 92100.0 0.41 664644.0 87200.0 0.43 0.5971 0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 B24 mock treatment 278964.0 -312000.0 -1.4 485515.0 -91900.0 -0.46 -1.3108 -0.8913 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C01 compound treatment 584167.0 -7180.0 -0.03 555708.0 -21700.0 -0.11 -0.0988 -0.8798 1869051 ChemDiv1_005325 Cc1cc(C)n2cc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])nc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C02 compound treatment 630282.0 38900.0 0.17 607303.0 29900.0 0.15 0.2279 0.9967 1559645 ChemDiv1_005326 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4)c(C(=O)OC(C)C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C03 compound treatment 668424.0 77100.0 0.35 659902.0 82500.0 0.41 0.5329 0.9965 1185665 ChemDiv1_005327 Cn1c(=O)n(C)c2nc(SCC(=O)c3ccc(F)cc3)[nH]c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C04 compound treatment 645868.0 54500.0 0.24 641692.0 64300.0 0.32 0.3977 0.9914 1645637 ChemDiv1_005328 Cc1c(NC(=O)c2cc(nc3ccccc23)c4cccc(Br)c4)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C05 compound treatment 701966.0 111000.0 0.5 679401.0 102000.0 0.51 0.7073 1.0 1187056 ChemDiv1_005329 Oc1nc(SCC(=O)c2c[nH]c3ccccc23)nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C06 compound treatment 663761.0 72400.0 0.32 642171.0 64700.0 0.32 0.456 1.0 1494240 ChemDiv1_005330 COc1ccc(cc1)c2cc(C(=O)N(CC=C)CC=C)c3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C07 compound treatment 697531.0 106000.0 0.48 727067.0 150000.0 0.74 0.8603 0.9769 1926394 ChemDiv1_005331 OC(=O)CCC(=O)N1N=C(CC1c2cccs2)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C08 compound treatment 743695.0 152000.0 0.68 730033.0 153000.0 0.76 1.0168 0.9987 1631757 ChemDiv1_005332 COc1ccc(cc1)N2C(=O)CC(Sc3nc(CC(C)C)ccc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C09 compound treatment 711045.0 120000.0 0.54 734478.0 157000.0 0.78 0.929 0.9834 1678449 ChemDiv1_005333 O=c1c(=Cc2ccccc2OCc3cccc4ccccc34)sc5nc6ccccc6n15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C10 compound treatment 694263.0 103000.0 0.46 713654.0 136000.0 0.67 0.8029 0.9827 1499573 ChemDiv1_005334 CC1CCc2nc(SC3CC(=O)N(C3=O)c4ccccc4)c(C#N)cc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C11 compound treatment 716671.0 125000.0 0.56 724256.0 147000.0 0.73 0.911 0.9918 1950008 ChemDiv1_005335 CCCOc1ccc(cc1)c2cc(C(=O)NCCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C12 compound treatment 703291.0 112000.0 0.5 697762.0 120000.0 0.6 0.7758 0.9963 1117928 ChemDiv1_005336 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C13 compound treatment 721278.0 130000.0 0.58 711895.0 134000.0 0.67 0.8823 0.9977 1381311 ChemDiv1_005337 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4cccc(OC)c4)c(C(=O)OC(C)C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C14 compound treatment 713570.0 122000.0 0.55 701665.0 124000.0 0.62 0.822 0.9983 1088388 ChemDiv1_005338 OC1(C2CCc3ccccc3C2=O)C(=O)Nc4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C15 compound treatment 754807.0 163000.0 0.73 722655.0 145000.0 0.72 1.0261 1.0 1566643 ChemDiv1_005339 Clc1ccc(cc1Cl)c2cc(C(=O)NC3CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C16 compound treatment 694748.0 103000.0 0.46 710595.0 133000.0 0.66 0.7937 0.985 1556213 ChemDiv1_005340 CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C17 compound treatment 710406.0 119000.0 0.53 724697.0 147000.0 0.73 0.8927 0.9881 1677644 ChemDiv1_005341 COc1cccc(c1)c2cc(C(=O)Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C18 compound treatment 701981.0 111000.0 0.5 701559.0 124000.0 0.61 0.785 0.9942 1972823 ChemDiv1_005342 CSc1nc(nc(n1)N2CC(=O)N(CCNS(=O)(=O)c3ccc(C)cc3)C2=N)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C19 compound treatment 722812.0 131000.0 0.59 703656.0 126000.0 0.63 0.8583 0.9995 1163490 ChemDiv1_005343 COC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4cccc(OC)c4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C20 compound treatment 688540.0 97200.0 0.44 674019.0 96600.0 0.48 0.646 0.9989 1972824 ChemDiv1_005344 OC(=O)C1CC=C(Cl)CC1C(=O)Nc2nccs2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C21 compound treatment 718025.0 127000.0 0.57 690121.0 113000.0 0.56 0.7957 1.0 1633899 ChemDiv1_005345 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C22 compound treatment 685298.0 94000.0 0.42 660843.0 83400.0 0.41 0.5896 1.0 1785278 ChemDiv1_005346 O=C(Nc1sc2CCCc2c1C#N)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C23 mock treatment 673858.0 82500.0 0.37 653364.0 75900.0 0.38 0.5271 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 C24 mock treatment 506840.0 -84500.0 -0.38 492267.0 -85200.0 -0.42 -0.5658 -0.9985 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D01 compound treatment 621520.0 30200.0 0.14 598188.0 20800.0 0.1 0.1682 0.9909 1972825 ChemDiv1_005347 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)c5ccccc5)n42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D02 compound treatment 652313.0 61000.0 0.27 638026.0 60600.0 0.3 0.4052 0.9989 1972826 ChemDiv1_005348 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D03 compound treatment 676518.0 85200.0 0.38 693489.0 116000.0 0.57 0.6761 0.9801 1316362 ChemDiv1_005349 COC(=O)CCSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D04 compound treatment 686209.0 94900.0 0.42 675869.0 98400.0 0.49 0.6451 0.9976 1163438 ChemDiv1_005350 CCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D05 compound treatment 696418.0 105000.0 0.47 716452.0 139000.0 0.69 0.8195 0.9827 1928272 ChemDiv1_005351 [O-][N+](=O)c1ccc(cc1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D06 compound treatment 673284.0 81900.0 0.37 724087.0 147000.0 0.73 0.7731 0.9499 1972827 ChemDiv1_005352 [O-][N+](=O)c1cccc(c1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D07 compound treatment 711990.0 121000.0 0.54 765510.0 188000.0 0.93 1.0407 0.9664 1493908 ChemDiv1_005353 CCOc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D08 compound treatment 723604.0 132000.0 0.59 748361.0 171000.0 0.85 1.0174 0.9847 1240853 ChemDiv1_005354 CN(C)c1ccc(cc1)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D09 compound treatment 731926.0 141000.0 0.63 742270.0 165000.0 0.82 1.0224 0.9917 1141789 ChemDiv1_005355 O=C(Nc1ccc(cc1)c2cn3ccccc3n2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D10 compound treatment 721704.0 130000.0 0.58 734321.0 157000.0 0.78 0.9622 0.99 1972828 ChemDiv1_005356 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(O)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D11 compound treatment 703619.0 112000.0 0.5 750113.0 173000.0 0.86 0.9602 0.9679 1410001 ChemDiv1_005357 COc1ccc2c(C)nc(Nc3nc(O)c4ccccc4n3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D12 compound treatment 726995.0 136000.0 0.61 747712.0 170000.0 0.84 1.0258 0.987 1972829 ChemDiv1_005358 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D13 compound treatment 742418.0 151000.0 0.68 781064.0 204000.0 1.01 1.1915 0.9811 1670478 ChemDiv1_005359 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D14 compound treatment 701232.0 110000.0 0.49 731016.0 154000.0 0.76 0.8858 0.9777 1972830 ChemDiv1_005360 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D15 compound treatment 739295.0 148000.0 0.66 784819.0 207000.0 1.03 1.1947 0.9774 1549210 ChemDiv1_005361 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D16 compound treatment 763492.0 172000.0 0.77 761852.0 184000.0 0.91 1.1909 0.9964 1972831 ChemDiv1_005362 CCOc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D17 compound treatment 777396.0 186000.0 0.83 771108.0 194000.0 0.96 1.2673 0.9975 1436630 ChemDiv1_005363 COc1ccc2N(C(=O)c3sc4ccccc4c3Cl)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D18 compound treatment 680383.0 89000.0 0.4 716218.0 139000.0 0.69 0.768 0.9664 1972832 ChemDiv1_005364 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5cccc(OC(=O)c6cccs6)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D19 compound treatment 761564.0 170000.0 0.76 775833.0 198000.0 0.98 1.2338 0.9921 1972833 ChemDiv1_005365 CCOc1ccc2nc(SCc3ccc(cc3)[N+](=O)[O-])nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D20 compound treatment 742042.0 151000.0 0.67 730623.0 153000.0 0.76 1.0136 0.9983 1972834 ChemDiv1_005366 Brc1ccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)nc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D21 compound treatment 744470.0 153000.0 0.69 754489.0 177000.0 0.88 1.1049 0.9926 1687575 ChemDiv1_005367 CC1CC(N(C(=O)c2cccc(C)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(C)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D22 compound treatment 716213.0 125000.0 0.56 714363.0 137000.0 0.68 0.8749 0.9954 1213750 ChemDiv1_005368 COc1ccccc1C(=O)On2c(C)nc3ccccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D23 mock treatment 716165.0 125000.0 0.56 710616.0 133000.0 0.66 0.8616 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 D24 mock treatment 215271.0 -376000.0 -1.68 487357.0 -90100.0 -0.45 -1.5059 -0.8647 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E01 compound treatment 617269.0 25900.0 0.12 571994.0 -5440.0 -0.03 0.063 0.5288 1972835 ChemDiv1_005369 [O-][N+](=O)c1ccc2[nH]c(SCc3nc4sccn4c3Br)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E02 compound treatment 628782.0 37400.0 0.17 640661.0 63200.0 0.31 0.34 0.9571 1710631 ChemDiv1_005370 CCOc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E03 compound treatment 669928.0 78600.0 0.35 691799.0 114000.0 0.57 0.6493 0.9737 1419901 ChemDiv1_005371 COC(=O)c1ccc(NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3[nH]2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E04 compound treatment 693056.0 102000.0 0.46 693150.0 116000.0 0.57 0.7273 0.9935 1212138 ChemDiv1_005372 CCc1ccc(cc1)c2cc(C(=O)N3CCN(C)CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E05 compound treatment 718838.0 127000.0 0.57 690585.0 113000.0 0.56 0.7999 1.0 1972836 ChemDiv1_005373 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E06 compound treatment 705962.0 115000.0 0.51 720029.0 143000.0 0.71 0.8623 0.9877 1214468 ChemDiv1_005374 COc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccc(C)n4)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E07 compound treatment 714278.0 123000.0 0.55 717082.0 140000.0 0.69 0.8783 0.9936 1204127 ChemDiv1_005375 COc1ccc(cc1)C2=NN(C(C2)c3cccs3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E08 compound treatment 697555.0 106000.0 0.48 719503.0 142000.0 0.7 0.8338 0.9818 1308765 ChemDiv1_005376 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E09 compound treatment 723544.0 132000.0 0.59 755079.0 178000.0 0.88 1.0407 0.9814 1718477 ChemDiv1_005377 O=c1c(=Cc2cccc(OCc3cccc4ccccc34)c2)sc5nc6ccccc6n15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E10 compound treatment 733356.0 142000.0 0.64 711454.0 134000.0 0.66 0.919 0.9998 1972837 ChemDiv1_005378 CC(C)c1c(C#N)c(N)nc(SC2CC(=O)N(C2=O)c3ccccc3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E11 compound treatment 741967.0 151000.0 0.67 737143.0 160000.0 0.79 1.0362 0.9968 1294280 ChemDiv1_005379 CCCOc1ccc(cc1)c2cc(C(=O)NCC3CCCO3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E12 compound treatment 700880.0 110000.0 0.49 739896.0 162000.0 0.8 0.9158 0.9718 1500031 ChemDiv1_005380 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c(CC)c(C)c3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E13 compound treatment 715045.0 124000.0 0.55 757112.0 180000.0 0.89 1.0209 0.9739 1249230 ChemDiv1_005381 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E14 compound treatment 691560.0 100000.0 0.45 707765.0 130000.0 0.65 0.7737 0.9842 1972838 ChemDiv1_005382 Brc1ccc2NC(=O)C(=Cc3nc4ccccc4c(=O)n3Cc5ccccc5)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E15 compound treatment 758451.0 167000.0 0.75 766782.0 189000.0 0.94 1.1922 0.9937 1472054 ChemDiv1_005383 COc1cccc(c1)c2cc(C(=O)NCc3ccc(F)cc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E16 compound treatment 749107.0 158000.0 0.71 746774.0 169000.0 0.84 1.0925 0.9963 1972839 ChemDiv1_005384 CC(C)N(C(=O)CN(C#N)c1nc(nc(n1)N(C)C)N(C)C)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E17 compound treatment 768516.0 177000.0 0.79 754270.0 177000.0 0.88 1.1802 0.9988 1305334 ChemDiv1_005385 COc1ccc(cc1)c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E18 compound treatment 731903.0 141000.0 0.63 706231.0 129000.0 0.64 0.8961 1.0 1479396 ChemDiv1_005386 CCNc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E19 compound treatment 755032.0 164000.0 0.73 727730.0 150000.0 0.74 1.0446 1.0 1268825 ChemDiv1_005387 Cc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E20 compound treatment 735413.0 144000.0 0.64 714924.0 137000.0 0.68 0.9376 0.9996 1640185 ChemDiv1_005388 CCOC(=O)c1c(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)sc6CCC(C)Cc16 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E21 compound treatment 743019.0 152000.0 0.68 737481.0 160000.0 0.79 1.0407 0.997 1676670 ChemDiv1_005389 Brc1ccc(cc1)c2cc(C(=O)NCc3ccccn3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E22 compound treatment 715607.0 124000.0 0.56 708102.0 131000.0 0.65 0.851 0.9972 1972840 ChemDiv1_005390 O=C1C2C3CC(C=C3)C2C(=O)N1CCCCCCN4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E23 mock treatment 714315.0 123000.0 0.55 667619.0 90200.0 0.45 0.7051 0.9946 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 E24 mock treatment 507499.0 -83800.0 -0.38 509991.0 -67400.0 -0.33 -0.5016 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F01 compound treatment 596744.0 5400.0 0.02 598855.0 21400.0 0.11 0.0921 0.8465 1972841 ChemDiv1_005391 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC(=O)c5ccc(Cl)cc5)n42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F02 compound treatment 647128.0 55800.0 0.25 635530.0 58100.0 0.29 0.3801 0.9975 1422452 ChemDiv1_005392 COc1ccc(cc1)C(=O)N2C(C)CC(N(C(=O)C)c3ccccc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F03 compound treatment 696674.0 105000.0 0.47 682848.0 105000.0 0.52 0.7026 0.9987 1368257 ChemDiv1_005393 CC1(Cc2ccccc2-c3nc(SCC(=O)N)n(Cc4ccccc4)c(=O)c31)C5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F04 compound treatment 685010.0 93700.0 0.42 698874.0 121000.0 0.6 0.7219 0.9844 1381370 ChemDiv1_005394 CCCOc1ccccc1C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(OC)cc5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F05 compound treatment 703342.0 112000.0 0.5 711249.0 134000.0 0.66 0.8232 0.9905 1524648 ChemDiv1_005395 COc1cc(OC)c(cc1OC)C2SCCN2C(=O)c3cc4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F06 compound treatment 696377.0 105000.0 0.47 746468.0 169000.0 0.84 0.9246 0.9628 1740766 ChemDiv1_005396 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F07 compound treatment 717800.0 126000.0 0.57 762997.0 186000.0 0.92 1.0503 0.9729 1457235 ChemDiv1_005397 O=C(Nc1c(nc2ccccn12)c3ccccc3)c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F08 compound treatment 722098.0 131000.0 0.59 724485.0 147000.0 0.73 0.929 0.9941 1972842 ChemDiv1_005398 NC1=C(C#N)C2(C(=O)Nc3ccc(F)cc32)c4c(n[nH]c4O1)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F09 compound treatment 728620.0 137000.0 0.61 764419.0 187000.0 0.93 1.0895 0.9801 1137033 ChemDiv1_005399 Cc1ccn2c(NC(=O)c3cc4cc(Br)ccc4oc3=O)c(nc2c1)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F10 compound treatment 716037.0 125000.0 0.56 738091.0 161000.0 0.8 0.9574 0.9849 1972843 ChemDiv1_005400 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F11 compound treatment 746728.0 155000.0 0.7 766580.0 189000.0 0.94 1.1544 0.9892 1776105 ChemDiv1_005401 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F12 compound treatment 729106.0 138000.0 0.62 739148.0 162000.0 0.8 1.0025 0.9916 1972844 ChemDiv1_005402 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F13 compound treatment 731283.0 140000.0 0.63 749740.0 172000.0 0.85 1.0465 0.9884 1551341 ChemDiv1_005403 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F14 compound treatment 697687.0 106000.0 0.48 728637.0 151000.0 0.75 0.8662 0.9761 1972845 ChemDiv1_005404 COc1cc(OC)c(C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F15 compound treatment 751486.0 160000.0 0.72 762118.0 185000.0 0.91 1.1538 0.9927 1972846 ChemDiv1_005405 COc1ccc2N(C(=O)CN3C(=O)C4CCCCC4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F16 compound treatment 847537.0 256000.0 1.15 877714.0 300000.0 1.49 1.8628 0.9917 1972847 ChemDiv1_005406 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F17 compound treatment 740101.0 149000.0 0.67 778908.0 201000.0 1.0 1.1766 0.9807 1706222 ChemDiv1_005407 COc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4sc5ccccc5c4Cl)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F18 compound treatment 696569.0 105000.0 0.47 715458.0 138000.0 0.68 0.8165 0.9835 1972848 ChemDiv1_005408 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c1OC(=O)N6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F19 compound treatment 752887.0 162000.0 0.72 730767.0 153000.0 0.76 1.0484 0.9997 1972849 ChemDiv1_005409 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F20 compound treatment 814385.0 223000.0 1.0 837807.0 260000.0 1.29 1.618 0.992 1972850 ChemDiv1_005410 CC1(C)CC(=O)c2sc(NC(=O)/C=C\c3ccco3)nc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F21 compound treatment 731138.0 140000.0 0.63 754696.0 177000.0 0.88 1.0634 0.9862 1347210 ChemDiv1_005411 COc1ccc(cc1)C(=O)N(C2CC(C)N(C(=O)c3ccc(OC)cc3)c4ccccc24)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F22 compound treatment 698035.0 107000.0 0.48 688624.0 111000.0 0.55 0.7272 0.9975 1178279 ChemDiv1_005412 COc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F23 mock treatment 705100.0 114000.0 0.51 699742.0 122000.0 0.61 0.7885 0.9963 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 F24 mock treatment 327958.0 -263000.0 -1.18 502348.0 -75100.0 -0.37 -1.0967 -0.8871 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G01 compound treatment 632202.0 40900.0 0.18 582010.0 4570.0 0.02 0.1454 0.7887 1869053 ChemDiv1_005413 Cc1csc2nc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])cn12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G02 compound treatment 628950.0 37600.0 0.17 610358.0 32900.0 0.16 0.2344 0.9999 1972851 ChemDiv1_005414 [O-][N+](=O)c1cc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)ccc1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G03 compound treatment 684228.0 92900.0 0.42 594509.0 17100.0 0.08 0.3538 0.8339 1227987 ChemDiv1_005415 CC(C)N(C(=O)CSc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G04 compound treatment 699813.0 108000.0 0.49 652856.0 75400.0 0.37 0.6075 0.9916 1301368 ChemDiv1_005416 Cc1cccc(c1)c2cc(C(=O)Nc3ccc(cc3)C(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G05 compound treatment 681666.0 90300.0 0.4 658790.0 81400.0 0.4 0.5709 1.0 1972852 ChemDiv1_005417 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCCOc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G06 compound treatment 707365.0 116000.0 0.52 706014.0 129000.0 0.64 0.8176 0.9949 1333118 ChemDiv1_005418 Clc1ccccc1c2cc(C(=O)Nc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G07 compound treatment 711995.0 121000.0 0.54 701134.0 124000.0 0.61 0.8152 0.998 1972853 ChemDiv1_005419 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G08 compound treatment 710171.0 119000.0 0.53 733117.0 156000.0 0.77 0.9215 0.9836 1722193 ChemDiv1_005420 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G09 compound treatment 793985.0 203000.0 0.91 802777.0 225000.0 1.12 1.4308 0.9947 1972854 ChemDiv1_005421 CCOc1cc(/C=C\2/C(=O)NC(=O)N(CC=C)C2=O)ccc1OCc3ccccc3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G10 compound treatment 717699.0 126000.0 0.57 737707.0 160000.0 0.79 0.9614 0.9862 1972855 ChemDiv1_005422 COc1ccc(cc1)N2C(=O)CC(Sc3nc(N)c(C#N)c(c3C#N)c4ccc(C)cc4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G11 compound treatment 737555.0 146000.0 0.65 734232.0 157000.0 0.78 1.012 0.9964 1676666 ChemDiv1_005423 CCC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)c3sc4cc(C)ccc4c3Cl)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G12 compound treatment 764745.0 173000.0 0.78 754430.0 177000.0 0.88 1.1689 0.9982 1972856 ChemDiv1_005424 O=C1CC(Sc2nc(ccc2C#N)c3ccccc3)C(=O)N1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G13 compound treatment 720965.0 130000.0 0.58 756453.0 179000.0 0.89 1.0374 0.9789 1158835 ChemDiv1_005425 CCOC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)N)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G14 compound treatment 720072.0 129000.0 0.58 722277.0 145000.0 0.72 0.9148 0.9941 1972857 ChemDiv1_005426 CN1C(=O)C(=Cc2nc3ccccc3c(=O)n2Cc4ccccc4)c5cc(Br)ccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G15 compound treatment 755600.0 164000.0 0.74 750679.0 173000.0 0.86 1.1268 0.997 1972858 ChemDiv1_005427 Cc1ccc(s1)c2cc(C(=O)Nc3ccc(F)c(c3)[N+](=O)[O-])c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G16 compound treatment 754890.0 164000.0 0.73 758392.0 181000.0 0.9 1.1515 0.9949 1972859 ChemDiv1_005428 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccc(Cl)cc3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G17 compound treatment 781691.0 190000.0 0.85 722363.0 145000.0 0.72 1.1102 0.9964 1529812 ChemDiv1_005429 CCN(CC)C(=O)c1cc(nc2ccccc12)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G18 compound treatment 698793.0 107000.0 0.48 717165.0 140000.0 0.69 0.8296 0.9842 1424874 ChemDiv1_005430 COC(=O)COC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G19 compound treatment 777753.0 186000.0 0.83 757016.0 180000.0 0.89 1.2191 0.9995 1704737 ChemDiv1_005431 COc1ccc(cc1)c2cc(C(=O)Nc3sc(C)c(C)c3C(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G20 compound treatment 743872.0 153000.0 0.68 723729.0 146000.0 0.72 0.9952 0.9996 1972860 ChemDiv1_005432 O=C(Nc1sc2CCCCc2c1C#N)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G21 compound treatment 736441.0 145000.0 0.65 731099.0 154000.0 0.76 0.9975 0.9969 1403754 ChemDiv1_005433 COC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccc(C)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G22 compound treatment 694633.0 103000.0 0.46 693828.0 116000.0 0.58 0.7346 0.994 1303203 ChemDiv1_005434 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G23 mock treatment 697480.0 106000.0 0.48 673172.0 95700.0 0.47 0.6713 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 G24 mock treatment 514624.0 -76700.0 -0.34 489597.0 -87800.0 -0.44 -0.5505 -0.9931 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H01 compound treatment 592402.0 1060.0 0.0 582516.0 5080.0 0.03 0.0211 0.8258 1972861 ChemDiv1_005435 CC1(C)Cc2c(CO1)sc3[nH]c(=S)n(c4ccc(Br)cc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H02 compound treatment 643323.0 52000.0 0.23 650321.0 72900.0 0.36 0.4198 0.9774 1872587 ChemDiv1_005436 CC1CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc4N1C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H03 compound treatment 675344.0 84000.0 0.38 702027.0 125000.0 0.62 0.7023 0.9718 1932257 ChemDiv1_005437 CON(C)c1nc(OCCNC(=O)COc2ccc(Cl)cc2Cl)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H04 compound treatment 677292.0 85900.0 0.38 715570.0 138000.0 0.68 0.7559 0.9629 1972862 ChemDiv1_005438 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H05 compound treatment 701945.0 111000.0 0.5 687167.0 110000.0 0.54 0.7345 0.9989 1463157 ChemDiv1_005439 Clc1ccccc1C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H06 compound treatment 705642.0 114000.0 0.51 738294.0 161000.0 0.8 0.9253 0.9771 1972863 ChemDiv1_005440 CC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H07 compound treatment 712790.0 121000.0 0.54 754153.0 177000.0 0.88 1.0034 0.9737 1723703 ChemDiv1_005441 COc1cccc(c1)C(=O)Nc2c(nc3cc(C)ccn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H08 compound treatment 687456.0 96100.0 0.43 707484.0 130000.0 0.64 0.7598 0.9807 1972864 ChemDiv1_005442 CCc1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H09 compound treatment 657972.0 66600.0 0.3 723566.0 146000.0 0.72 0.7228 0.9232 1972865 ChemDiv1_005443 Cc1ccn2cc(nc2c1)c3cccc(NC(=O)/C=C\C(=O)O)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H10 compound treatment 701221.0 110000.0 0.49 746335.0 169000.0 0.84 0.9394 0.9679 1972866 ChemDiv1_005444 COc1ccccc1C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H11 compound treatment 730319.0 139000.0 0.62 764055.0 187000.0 0.92 1.0936 0.9814 1536947 ChemDiv1_005445 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H12 compound treatment 711339.0 120000.0 0.54 748687.0 171000.0 0.85 0.9797 0.9757 1972867 ChemDiv1_005446 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cc(OC)c(OC)c(OC)c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H13 compound treatment 715469.0 124000.0 0.56 775440.0 198000.0 0.98 1.0865 0.9638 1541600 ChemDiv1_005447 COc1ccc(cc1)C(=O)N2C(C)CC(Nc3ccc(C)cc3)c4cc(C)ccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H14 compound treatment 697601.0 106000.0 0.48 714421.0 137000.0 0.68 0.8162 0.9849 1972868 ChemDiv1_005448 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H15 compound treatment 730834.0 139000.0 0.62 769779.0 192000.0 0.95 1.1153 0.979 1972869 ChemDiv1_005449 CCOc1ccc2N(C(=O)CN3C(=O)C4CCCCC4C3=O)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H16 compound treatment 719422.0 128000.0 0.57 747694.0 170000.0 0.84 1.0018 0.9823 1972870 ChemDiv1_005450 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H17 compound treatment 708154.0 117000.0 0.52 772701.0 195000.0 0.97 1.0537 0.9583 1285771 ChemDiv1_005451 COc1cccc2-c3c(ssc3=S)C(C)(C)N(C(=O)c4sc5ccccc5c4Cl)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H18 compound treatment 703794.0 112000.0 0.5 739261.0 162000.0 0.8 0.9228 0.9749 1972871 ChemDiv1_005452 COc1cc(ccc1OC(=O)c2ccco2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H19 compound treatment 753346.0 162000.0 0.73 767153.0 190000.0 0.94 1.1773 0.9918 1501502 ChemDiv1_005453 Cc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)CC(C)(c4ccccc4)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H20 compound treatment 700971.0 110000.0 0.49 742596.0 165000.0 0.82 0.9255 0.9701 1290704 ChemDiv1_005454 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H21 compound treatment 711790.0 120000.0 0.54 740760.0 163000.0 0.81 0.9534 0.9805 1377902 ChemDiv1_005455 CC1CC(N(C(=O)c2cccc(Br)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H22 compound treatment 703394.0 112000.0 0.5 732782.0 155000.0 0.77 0.8988 0.9785 1478471 ChemDiv1_005456 Fc1ccccc1C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H23 mock treatment 694328.0 103000.0 0.46 686688.0 109000.0 0.54 0.7087 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 H24 mock treatment 489713.0 -102000.0 -0.45 518356.0 -59100.0 -0.29 -0.5286 -0.9772 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I01 compound treatment 620333.0 29000.0 0.13 582295.0 4860.0 0.02 0.1088 0.8242 1972872 ChemDiv1_005457 Cc1csc2nc(CSc3nc4cc(ccc4[nH]3)[N+](=O)[O-])c(Br)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I02 compound treatment 642581.0 51200.0 0.23 615854.0 38400.0 0.19 0.2968 0.9957 1245911 ChemDiv1_005458 CCc1ccc(cc1)c2cc(C(=O)NCc3ccncc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I03 compound treatment 687746.0 96400.0 0.43 678431.0 101000.0 0.5 0.6589 0.9973 1701313 ChemDiv1_005459 CCOc1ccc2nc(NC(=O)C3CC(=CCC3C(=O)O)C)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I04 compound treatment 696453.0 105000.0 0.47 684049.0 107000.0 0.53 0.7062 0.9983 1949458 ChemDiv1_005460 COc1ccc(cc1)c2nc3ccccc3c(C(=O)Nc4ccc(cc4)C(=O)C)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I05 compound treatment 696951.0 106000.0 0.47 661717.0 84300.0 0.42 0.6295 0.9981 1972873 ChemDiv1_005461 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccccc3CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I06 compound treatment 725198.0 134000.0 0.6 691159.0 114000.0 0.56 0.822 0.9995 1296184 ChemDiv1_005462 Cc1ccc(c(C)c1)c2cc(C(=O)NCC3CCCO3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I07 compound treatment 726858.0 136000.0 0.61 715894.0 138000.0 0.69 0.9139 0.9981 1582790 ChemDiv1_005463 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I08 compound treatment 737696.0 146000.0 0.66 720384.0 143000.0 0.71 0.964 0.9992 1619900 ChemDiv1_005464 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCCCc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I09 compound treatment 787446.0 196000.0 0.88 826142.0 249000.0 1.23 1.4919 0.9862 1972874 ChemDiv1_005465 CC(C)(C)c1ccc(OCCOc2ccc(/C=C\3/NC(=S)NC3=O)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I10 compound treatment 754855.0 164000.0 0.73 725967.0 149000.0 0.74 1.0378 1.0 1237419 ChemDiv1_005466 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(Cl)cc3Cl)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I11 compound treatment 730750.0 139000.0 0.62 723772.0 146000.0 0.72 0.9539 0.9972 1972875 ChemDiv1_005467 COc1ccc(cc1OC)c2cc(C(=O)Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I12 compound treatment 727434.0 136000.0 0.61 736035.0 159000.0 0.79 0.9863 0.9921 1565271 ChemDiv1_005468 Cc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I13 compound treatment 722644.0 131000.0 0.59 705797.0 128000.0 0.64 0.8652 0.9992 1972876 ChemDiv1_005469 CCOc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)s4)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I14 compound treatment 814784.0 223000.0 1.0 770658.0 193000.0 0.96 1.3841 0.9998 1972877 ChemDiv1_005470 OC(=O)c1ccc(cc1)n2c(/C=C\c3cc(Br)ccc3O)nc4ccccc4c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I15 compound treatment 770252.0 179000.0 0.8 776613.0 199000.0 0.99 1.264 0.9946 1388193 ChemDiv1_005471 CCc1ccc(cc1)c2cc(C(=O)NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I16 compound treatment 730054.0 139000.0 0.62 730839.0 153000.0 0.76 0.9764 0.995 1931352 ChemDiv1_005472 CC1N(C(=N)N(C1=O)c2ccc(Cl)c(Cl)c2)c3nc(nc(n3)N(C)C)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I17 compound treatment 765419.0 174000.0 0.78 761648.0 184000.0 0.91 1.1963 0.9969 1555030 ChemDiv1_005473 Cc1ccc2c(Cl)c(sc2c1)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4cc(C)nc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I18 compound treatment 713580.0 122000.0 0.55 713802.0 136000.0 0.68 0.8646 0.9945 1946133 ChemDiv1_005474 Cn1cc(/C=C/c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I19 compound treatment 759358.0 168000.0 0.75 728274.0 151000.0 0.75 1.0602 1.0 1412115 ChemDiv1_005475 Cc1c(nc2ccccc2c1C(=O)NCCN3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I20 compound treatment 738458.0 147000.0 0.66 698794.0 121000.0 0.6 0.8908 0.999 1972878 ChemDiv1_005476 CC1CCc2sc(NC(=O)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O)c(C#N)c2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I21 compound treatment 751510.0 160000.0 0.72 746826.0 169000.0 0.84 1.1003 0.9969 1972879 ChemDiv1_005477 CC(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I22 compound treatment 713802.0 122000.0 0.55 668952.0 91500.0 0.45 0.7082 0.9955 1435974 ChemDiv1_005478 CCCN(c1nc(C)c(Br)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I23 mock treatment 701915.0 111000.0 0.49 691397.0 114000.0 0.56 0.7492 0.9979 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 I24 mock treatment 517643.0 -73700.0 -0.33 502893.0 -74500.0 -0.37 -0.4944 -0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J01 compound treatment 620098.0 28800.0 0.13 608582.0 31100.0 0.15 0.2001 0.9959 1972880 ChemDiv1_005479 CCC1(C)Cc2c(CO1)sc3[nH]c(=S)n(c4ccc(OC)cc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J02 compound treatment 646786.0 55400.0 0.25 633352.0 55900.0 0.28 0.3714 0.9985 1972881 ChemDiv1_005480 CCOC(=O)CC(=O)CSc1nc(C)c2cc(C)c(C)cc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J03 compound treatment 678564.0 87200.0 0.39 693215.0 116000.0 0.57 0.6816 0.9824 1932201 ChemDiv1_005481 CON(C)c1nc(OCCNC(=O)COc2ccc(Cl)cc2C)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J04 compound treatment 667342.0 76000.0 0.34 691234.0 114000.0 0.56 0.6392 0.9708 1730756 ChemDiv1_005482 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J05 compound treatment 689283.0 97900.0 0.44 698429.0 121000.0 0.6 0.7338 0.9882 1695143 ChemDiv1_005483 CN(C)c1ccc(cc1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J06 compound treatment 698475.0 107000.0 0.48 738051.0 161000.0 0.8 0.9017 0.9706 1972882 ChemDiv1_005484 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J07 compound treatment 707697.0 116000.0 0.52 743867.0 166000.0 0.82 0.9513 0.9755 1972883 ChemDiv1_005485 Cc1ccn2c(NC(=O)c3cccc(c3)[N+](=O)[O-])c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J08 compound treatment 740174.0 149000.0 0.67 763825.0 186000.0 0.92 1.124 0.9872 1972884 ChemDiv1_005486 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J09 compound treatment 694818.0 103000.0 0.46 724653.0 147000.0 0.73 0.8432 0.976 1972885 ChemDiv1_005487 Cc1ccc(cc1[N+](=O)[O-])S(=O)(=O)Nc2cccc(c2)c3cn4ccccc4n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J10 compound treatment 685560.0 94200.0 0.42 733964.0 157000.0 0.78 0.8465 0.959 1972886 ChemDiv1_005488 CCOc1ccccc1C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J11 compound treatment 700676.0 109000.0 0.49 755398.0 178000.0 0.88 0.9694 0.9614 1430400 ChemDiv1_005489 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J12 compound treatment 649826.0 58500.0 0.26 723875.0 146000.0 0.73 0.6981 0.9051 1972887 ChemDiv1_005490 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c4cccs4)c23)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J13 compound treatment 704802.0 113000.0 0.51 755334.0 178000.0 0.88 0.9823 0.9657 1255655 ChemDiv1_005491 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)CN4C(=O)c5ccccc5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J14 compound treatment 680709.0 89400.0 0.4 731110.0 154000.0 0.76 0.8212 0.9549 1972888 ChemDiv1_005492 COc1cc(ccc1OC(=O)c2cccs2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J15 compound treatment 736216.0 145000.0 0.65 750451.0 173000.0 0.86 1.0646 0.9905 1940534 ChemDiv1_005493 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CN4C(=O)C5CCCCC5C4=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J16 compound treatment 728385.0 137000.0 0.61 731255.0 154000.0 0.76 0.9726 0.9942 1972889 ChemDiv1_005494 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J17 compound treatment 743116.0 152000.0 0.68 753146.0 176000.0 0.87 1.0959 0.9925 1487260 ChemDiv1_005495 Cn1cnnc1SCC(=O)N2c3ccccc3-c4c(ssc4=S)C2(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J18 compound treatment 693844.0 103000.0 0.46 739437.0 162000.0 0.8 0.8919 0.9648 1972890 ChemDiv1_005496 COc1cc(ccc1OC(=O)c2cccs2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J19 compound treatment 693066.0 102000.0 0.46 723843.0 146000.0 0.73 0.8348 0.9748 1972891 ChemDiv1_005497 CCc1ccc(cc1)C2(C)CC(C)(C)N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])c5ccccc52 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J20 compound treatment 689445.0 98100.0 0.44 736384.0 159000.0 0.79 0.8673 0.962 1972892 ChemDiv1_005498 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J21 compound treatment 733144.0 142000.0 0.63 697692.0 120000.0 0.6 0.8701 0.9995 1972893 ChemDiv1_005499 CCCc1ccc(cc1)C(=O)N2C(C)CC(N(C(=O)c3ccc(cc3)[N+](=O)[O-])c4ccccc4)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J22 compound treatment 699057.0 108000.0 0.48 718100.0 141000.0 0.7 0.8337 0.9838 1972894 ChemDiv1_005500 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)C4CCCCC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J23 mock treatment 690719.0 99400.0 0.44 705461.0 128000.0 0.63 0.763 0.9849 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 J24 mock treatment 195097.0 -396000.0 -1.77 525917.0 -51500.0 -0.26 -1.4347 -0.8006 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K01 compound treatment 631243.0 39900.0 0.18 577492.0 56.0 0.0 0.1265 0.7082 1972895 ChemDiv1_005501 [O-][N+](=O)c1ccc2sc(SCc3nc4ncccn4c3Br)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K02 compound treatment 656012.0 64700.0 0.29 622667.0 45200.0 0.22 0.3631 0.992 1271912 ChemDiv1_005502 Cc1cccc(c1)c2cc(C(=O)NCc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K03 compound treatment 704098.0 113000.0 0.5 661699.0 84300.0 0.42 0.6521 0.9955 1573066 ChemDiv1_005503 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCCCC4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K04 compound treatment 679310.0 88000.0 0.39 668489.0 91100.0 0.45 0.5974 0.9977 1242495 ChemDiv1_005504 CCOC(=O)c1c(NC(=O)c2sc3ccccc3c2Cl)sc4CC(CCc14)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K05 compound treatment 704369.0 113000.0 0.51 704220.0 127000.0 0.63 0.8019 0.9943 1926817 ChemDiv1_005505 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K06 compound treatment 691253.0 99900.0 0.45 695253.0 118000.0 0.58 0.7289 0.9914 1528898 ChemDiv1_005506 Clc1ccccc1c2cc(C(=O)NCc3ccccn3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K07 compound treatment 758374.0 167000.0 0.75 734427.0 157000.0 0.78 1.0786 0.9998 1972896 ChemDiv1_005507 CCOc1ccc2cc(C3=NN(C(C3)c4ccc(C)cc4)C(=O)CCC(=O)O)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K08 compound treatment 704257.0 113000.0 0.51 706919.0 129000.0 0.64 0.811 0.993 1193279 ChemDiv1_005508 COc1ccc(cc1)N2C(=O)CC(Sc3nc4CCC(C)Cc4cc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K09 compound treatment 701741.0 110000.0 0.49 708061.0 131000.0 0.65 0.807 0.9911 1157191 ChemDiv1_005509 CCOC(=O)c1c(NC(=O)c2sc3cc(F)ccc3c2Cl)scc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K10 compound treatment 695083.0 104000.0 0.46 705735.0 128000.0 0.64 0.7778 0.9881 1972897 ChemDiv1_005510 Cc1nc(SC2CC(=O)N(C2=O)c3ccc(Br)cc3)c(C#N)c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K11 compound treatment 721127.0 130000.0 0.58 714552.0 137000.0 0.68 0.8911 0.997 1373098 ChemDiv1_005511 COc1ccc(cc1OC)c2cc(C(=O)Nc3cc(C)on3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K12 compound treatment 648403.0 57100.0 0.26 700396.0 123000.0 0.61 0.6113 0.9255 1434985 ChemDiv1_005512 OCCN1CCN(CC1)c2nc(nc(n2)N3CCCCC3)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K13 compound treatment 723099.0 132000.0 0.59 703194.0 126000.0 0.62 0.8576 0.9996 1541895 ChemDiv1_005513 COc1ccccc1N2CCN(CC2)C(=O)c3cc(nc4ccccc34)c5ccc(C)s5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K14 compound treatment 699209.0 108000.0 0.48 697555.0 120000.0 0.6 0.7622 0.9946 1933528 ChemDiv1_005514 CC(C)C1(CN2CC3(CN(C1)C24C(=O)Nc5ccccc54)C(C)C)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K15 compound treatment 758112.0 167000.0 0.75 743844.0 166000.0 0.82 1.1108 0.9988 1481547 ChemDiv1_005515 Cc1c(nc2ccccc2c1C(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K16 compound treatment 753488.0 162000.0 0.73 716643.0 139000.0 0.69 1.0009 0.9997 1972898 ChemDiv1_005516 COc1nc(nc(n1)N2C(C)C(=O)N(C2=N)c3ccc(Cl)c(Cl)c3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K17 compound treatment 761858.0 171000.0 0.76 715373.0 138000.0 0.68 1.0229 0.9985 1972899 ChemDiv1_005517 Cc1ccc(s1)c2cc(C(=O)NCCCn3ccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K18 compound treatment 730413.0 139000.0 0.62 695952.0 119000.0 0.59 0.8553 0.9996 1972900 ChemDiv1_005518 CN1C(=O)C(=Cc2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])c5cc(Br)ccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K19 compound treatment 771694.0 180000.0 0.81 738046.0 161000.0 0.8 1.1335 1.0 1716304 ChemDiv1_005519 Clc1ccc(cc1Cl)c2cc(C(=O)N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K20 compound treatment 726131.0 135000.0 0.6 684899.0 107000.0 0.53 0.8031 0.9981 1351102 ChemDiv1_005520 CCOC(=O)c1c(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)sc6CCCCc16 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K21 compound treatment 730607.0 139000.0 0.62 732665.0 155000.0 0.77 0.9846 0.9946 1357909 ChemDiv1_005521 CCOC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(OC)c(OC)c4)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K22 compound treatment 725716.0 134000.0 0.6 704272.0 127000.0 0.63 0.8696 0.9998 1575220 ChemDiv1_005522 CCCN(c1nc(C)c(Cl)c(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K23 mock treatment 721369.0 130000.0 0.58 677411.0 100000.0 0.5 0.7618 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 K24 mock treatment 639731.0 48400.0 0.22 498287.0 -79100.0 -0.39 -0.1241 -0.277 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L01 compound treatment 596279.0 4940.0 0.02 584178.0 6740.0 0.03 0.0392 0.9799 1972901 ChemDiv1_005523 CCC1(C)Cc2c(CO1)sc3nc(SC)n(c4ccc(OC)cc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L02 compound treatment 624703.0 33400.0 0.15 596722.0 19300.0 0.1 0.1732 0.9767 1972902 ChemDiv1_005524 COc1ccc(Nc2nc(Cl)nc(Nc3cccc(c3)[N+](=O)[O-])n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L03 compound treatment 669826.0 78500.0 0.35 696599.0 119000.0 0.59 0.6658 0.9693 1257403 ChemDiv1_005525 Cc1sc(NC(=O)c2cc3cc(Br)ccc3oc2=O)nc1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L04 compound treatment 670668.0 79300.0 0.36 685546.0 108000.0 0.54 0.6298 0.9801 1972903 ChemDiv1_005526 COc1ccc(cc1OC)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L05 compound treatment 663807.0 72500.0 0.32 689362.0 112000.0 0.55 0.6214 0.9674 1233432 ChemDiv1_005527 Cc1nc(cs1)c2ccc(NC(=O)c3cc4cc(Br)ccc4oc3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L06 compound treatment 681324.0 90000.0 0.4 705013.0 128000.0 0.63 0.7317 0.9763 1972904 ChemDiv1_005528 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L07 compound treatment 715787.0 124000.0 0.56 717197.0 140000.0 0.69 0.8835 0.9942 1784263 ChemDiv1_005529 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L08 compound treatment 677940.0 86600.0 0.39 665519.0 88100.0 0.44 0.5826 0.9983 1972905 ChemDiv1_005530 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L09 compound treatment 698662.0 107000.0 0.48 727121.0 150000.0 0.74 0.864 0.9779 1572388 ChemDiv1_005531 O=S(=O)(Nc1cccc(c1)c2cn3ccccc3n2)c4ccc5ccccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L10 compound treatment 800599.0 209000.0 0.94 797522.0 220000.0 1.09 1.4333 0.9971 1972906 ChemDiv1_005532 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L11 compound treatment 682698.0 91400.0 0.41 730662.0 153000.0 0.76 0.8259 0.9579 1216629 ChemDiv1_005533 CC1CC(N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc4)c5ccccc5N1C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L12 compound treatment 656124.0 64800.0 0.29 704467.0 127000.0 0.63 0.65 0.9381 1972907 ChemDiv1_005534 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4cc(Br)ccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L13 compound treatment 684636.0 93300.0 0.42 726442.0 149000.0 0.74 0.8172 0.9636 1170338 ChemDiv1_005535 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)COc4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L14 compound treatment 712600.0 121000.0 0.54 717321.0 140000.0 0.69 0.8738 0.9927 1972908 ChemDiv1_005536 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L15 compound treatment 714621.0 123000.0 0.55 754925.0 177000.0 0.88 1.0119 0.9748 1972909 ChemDiv1_005537 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)C4CCCCC4C3=O)c5ccccc25)S1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L16 compound treatment 715602.0 124000.0 0.56 723881.0 146000.0 0.73 0.9063 0.9914 1972910 ChemDiv1_005538 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L17 compound treatment 720056.0 129000.0 0.58 747405.0 170000.0 0.84 1.0028 0.9829 1289799 ChemDiv1_005539 Cc1ccc2-c3c(ssc3=S)C(C)(C)N(C(=O)CSc4nc5ccccc5o4)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L18 compound treatment 715645.0 124000.0 0.56 712100.0 135000.0 0.67 0.8652 0.9959 1972911 ChemDiv1_005540 CCOc1cc(ccc1OC(=O)c2ccco2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L19 compound treatment 716585.0 125000.0 0.56 748966.0 172000.0 0.85 0.9973 0.9796 1366937 ChemDiv1_005541 CC1CC(N(C(=O)c2ccc(Cl)cc2)c3ccccc3)c4ccccc4N1C(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L20 compound treatment 704534.0 113000.0 0.51 696392.0 119000.0 0.59 0.775 0.9972 1371364 ChemDiv1_005542 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Br)ccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L21 compound treatment 708190.0 117000.0 0.52 719766.0 142000.0 0.71 0.8684 0.9892 1972912 ChemDiv1_005543 CCCCCC(=O)N(C1CC(C)N(C(=O)c2cccc(OC)c2)c3ccccc13)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L22 compound treatment 687917.0 96600.0 0.43 697666.0 120000.0 0.6 0.7268 0.9876 1157436 ChemDiv1_005544 COc1ccc(Br)c(c1)C(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L23 mock treatment 688703.0 97400.0 0.44 684933.0 107000.0 0.53 0.6847 0.9951 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 L24 mock treatment 199892.0 -391000.0 -1.75 491450.0 -86000.0 -0.43 -1.5402 -0.8541 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M01 compound treatment 624064.0 32700.0 0.15 583739.0 6300.0 0.03 0.1256 0.839 1972913 ChemDiv1_005545 Cc1csc2nc(CSc3nc4cc(ccc4s3)[N+](=O)[O-])c(Br)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M02 compound treatment 647067.0 55700.0 0.25 625177.0 47700.0 0.24 0.3436 0.9996 1247316 ChemDiv1_005546 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)c(Cl)c4)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M03 compound treatment 688708.0 97400.0 0.44 638364.0 60900.0 0.3 0.5216 0.9839 1972914 ChemDiv1_005547 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CNCCO)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M04 compound treatment 672375.0 81000.0 0.36 653378.0 75900.0 0.38 0.5225 0.9998 1198463 ChemDiv1_005548 CCN(CC)C(=O)c1sc(NC(=O)c2c(C)onc2c3ccccc3Cl)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M05 compound treatment 789960.0 199000.0 0.89 815080.0 238000.0 1.18 1.4611 0.9904 1972915 ChemDiv1_005549 Clc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M06 compound treatment 679875.0 88500.0 0.4 654037.0 76600.0 0.38 0.5486 0.9998 1236558 ChemDiv1_005550 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M07 compound treatment 742436.0 151000.0 0.68 717453.0 140000.0 0.69 0.9687 0.9999 1701106 ChemDiv1_005551 CCOc1ccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M08 compound treatment 704786.0 113000.0 0.51 674005.0 96600.0 0.48 0.6973 0.9996 1972916 ChemDiv1_005552 COc1ccc(cc1)N2C(=O)CC(Sc3nc(N)c(C#N)c(c3C#N)c4ccccc4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M09 compound treatment 741318.0 150000.0 0.67 688093.0 111000.0 0.55 0.8623 0.9949 1714671 ChemDiv1_005553 CCOc1cccc(c1)c2cc(C(=O)Nc3cc(C)on3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M10 compound treatment 735620.0 144000.0 0.65 688687.0 111000.0 0.55 0.8464 0.9969 1584909 ChemDiv1_005554 O=C1CC(Sc2nc3CCCCCc3cc2C#N)C(=O)N1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M11 compound treatment 751154.0 160000.0 0.72 713342.0 136000.0 0.67 0.9819 0.9995 1242438 ChemDiv1_005555 O=C(Nc1ccc2OCOc2c1)c3cc(nc4ccccc34)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M12 compound treatment 677906.0 86600.0 0.39 656548.0 79100.0 0.39 0.5511 1.0 1972917 ChemDiv1_005556 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCSc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M13 compound treatment 723908.0 133000.0 0.59 700900.0 123000.0 0.61 0.8521 0.9999 1643117 ChemDiv1_005557 Clc1ccc(cc1)c2cc(C(=O)N3CCCCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M14 compound treatment 728692.0 137000.0 0.61 692444.0 115000.0 0.57 0.8376 0.9993 1972918 ChemDiv1_005558 Brc1ccc(cc1)n2c(C=C3C(=O)Nc4ccccc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M15 compound treatment 727269.0 136000.0 0.61 713770.0 136000.0 0.68 0.9078 0.9986 1972919 ChemDiv1_005559 COc1cccc(c1)c2cc(C(=O)NCCCn3ccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M16 compound treatment 717070.0 126000.0 0.56 695404.0 118000.0 0.58 0.8112 0.9998 1309660 ChemDiv1_005560 CCNc1nc(NC(C)CC)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M17 compound treatment 765012.0 174000.0 0.78 705008.0 128000.0 0.63 0.9966 0.9947 1631818 ChemDiv1_005561 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3F)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M18 compound treatment 734399.0 143000.0 0.64 701967.0 125000.0 0.62 0.889 0.9998 1972920 ChemDiv1_005562 CC1(C)Cc2c(C#N)c(NC(=O)CN3C(=O)C4CC=C(Cl)CC4C3=O)sc2CO1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M19 compound treatment 769625.0 178000.0 0.8 737521.0 160000.0 0.79 1.1251 1.0 1594627 ChemDiv1_005563 CCN(CC)C(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M20 compound treatment 722331.0 131000.0 0.59 692624.0 115000.0 0.57 0.8181 0.9999 1972921 ChemDiv1_005564 O=C(Nc1cccc2ccccc12)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M21 compound treatment 738187.0 147000.0 0.66 719170.0 142000.0 0.7 0.9613 0.9995 1972922 ChemDiv1_005565 [O-][N+](=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M22 compound treatment 719492.0 128000.0 0.57 682249.0 105000.0 0.52 0.7728 0.9988 1609074 ChemDiv1_005566 CCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M23 mock treatment 723935.0 133000.0 0.59 648255.0 70800.0 0.35 0.6678 0.9685 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 M24 mock treatment 473611.0 -118000.0 -0.53 420482.0 -157000.0 -0.78 -0.9224 -0.9821 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N01 compound treatment 608088.0 16700.0 0.07 582102.0 4670.0 0.02 0.0693 0.8841 1972923 ChemDiv1_005567 CCOC(=O)CSc1nc2sc3COC(C)(CC)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N02 compound treatment 649769.0 58400.0 0.26 635508.0 58100.0 0.29 0.3884 0.9989 1418520 ChemDiv1_005568 COc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c4ccccc4n3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N03 compound treatment 645074.0 53700.0 0.24 674722.0 97300.0 0.48 0.5109 0.9484 1534034 ChemDiv1_005569 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3cccc(c3)c4cn5ccccc5n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N04 compound treatment 640733.0 49400.0 0.22 645807.0 68400.0 0.34 0.3958 0.9786 1972924 ChemDiv1_005570 CCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N05 compound treatment 630966.0 39600.0 0.18 679913.0 102000.0 0.51 0.4844 0.9008 1657316 ChemDiv1_005571 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3ccc(cc3)c4cn5ccccc5n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N06 compound treatment 642783.0 51400.0 0.23 675155.0 97700.0 0.48 0.5051 0.9423 1785310 ChemDiv1_005572 CC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N07 compound treatment 636464.0 45100.0 0.2 690605.0 113000.0 0.56 0.5392 0.9049 1784264 ChemDiv1_005573 Cc1ccn2c(NC(=O)c3ccc(cc3)[N+](=O)[O-])c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N08 compound treatment 660847.0 69500.0 0.31 678174.0 101000.0 0.5 0.5729 0.9741 1972925 ChemDiv1_005574 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(Br)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N09 compound treatment 691219.0 99900.0 0.45 693474.0 116000.0 0.57 0.7226 0.9923 1271696 ChemDiv1_005575 Cc1nc(sc1C(=O)Nc2ccc(cc2)c3cn4ccccc4n3)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N10 compound treatment 718068.0 127000.0 0.57 656074.0 78600.0 0.39 0.6766 0.9832 1972926 ChemDiv1_005576 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N11 compound treatment 718244.0 127000.0 0.57 710223.0 133000.0 0.66 0.8668 0.9973 1972927 ChemDiv1_005577 CCCCCC(=O)N1C(C)CC(N(C(=O)c2cccc(OC)c2)c3ccccc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N12 compound treatment 668281.0 76900.0 0.34 671775.0 94300.0 0.47 0.574 0.9887 1972928 ChemDiv1_005578 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N13 compound treatment 673887.0 82500.0 0.37 699949.0 123000.0 0.61 0.6904 0.9717 1972929 ChemDiv1_005579 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CSc3nc4ccccc4o3)c5ccc(OC)cc25)S1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N14 compound treatment 675515.0 84200.0 0.38 687338.0 110000.0 0.54 0.6514 0.9838 1972930 ChemDiv1_005580 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccccc5Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N15 compound treatment 668670.0 77300.0 0.35 726728.0 149000.0 0.74 0.7677 0.9402 1972931 ChemDiv1_005581 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)CN3C(=O)C4CCCCC4C3=O)c5cc(C)ccc25)S1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N16 compound treatment 674339.0 83000.0 0.37 710909.0 133000.0 0.66 0.7302 0.9628 1972932 ChemDiv1_005582 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N17 compound treatment 696317.0 105000.0 0.47 722850.0 145000.0 0.72 0.8416 0.9786 1330507 ChemDiv1_005583 Cc1cc(C)c2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N18 compound treatment 684287.0 92900.0 0.42 696749.0 119000.0 0.59 0.7121 0.9852 1541812 ChemDiv1_005584 CCC(Sc1nc2ccccc2o1)C(=O)Nc3ccc(Cl)cn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N19 compound treatment 700000.0 109000.0 0.49 695129.0 118000.0 0.58 0.7562 0.9959 1946567 ChemDiv1_005585 COc1ccc2nc(NC3=NC(CC(=O)N3)c4ccccc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N20 compound treatment 712647.0 121000.0 0.54 696468.0 119000.0 0.59 0.8009 0.9992 1972933 ChemDiv1_005586 [O-][N+](=O)c1cc(C(=O)Nn2c(nc3ccccc3c2=O)C4CCCCC4)c(Cl)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N21 compound treatment 727269.0 136000.0 0.61 704962.0 128000.0 0.63 0.877 0.9998 1283410 ChemDiv1_005587 COc1ccc(OCC(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N22 compound treatment 681252.0 89900.0 0.4 664433.0 87000.0 0.43 0.5893 0.9994 1333556 ChemDiv1_005588 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)c4cc5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N23 mock treatment 694468.0 103000.0 0.46 678054.0 101000.0 0.5 0.6789 0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 N24 mock treatment 529472.0 -61900.0 -0.28 154237.0 -423000.0 -2.1 -1.6782 -0.7936 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O01 compound treatment 636494.0 45200.0 0.2 569162.0 -8270.0 -0.04 0.1139 0.5525 1972934 ChemDiv1_005589 Cc1cccc2nc(CSc3nc4cc(ccc4o3)[N+](=O)[O-])c(Br)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O02 compound treatment 636313.0 45000.0 0.2 620177.0 42700.0 0.21 0.2921 0.9997 1507899 ChemDiv1_005590 Brc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccco4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O03 compound treatment 687902.0 96600.0 0.43 649057.0 71600.0 0.35 0.5565 0.9952 1370080 ChemDiv1_005591 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccc(F)cc4F)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O04 compound treatment 654454.0 63100.0 0.28 618127.0 40700.0 0.2 0.3423 0.9863 1453072 ChemDiv1_005592 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccc(C)o4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O05 compound treatment 1109335.0 518000.0 2.32 1008392.0 431000.0 2.13 3.1492 0.9991 1505219 ChemDiv1_005593 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O06 compound treatment 664831.0 73500.0 0.33 641539.0 64100.0 0.32 0.4572 0.9998 1713098 ChemDiv1_005594 CCC1CCc2c(C(=O)OC)c(NC(=O)c3sc4ccccc4c3Cl)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O07 compound treatment 702610.0 111000.0 0.5 648764.0 71300.0 0.35 0.602 0.9859 1130872 ChemDiv1_005595 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3OC)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O08 compound treatment 669157.0 77800.0 0.35 652291.0 74900.0 0.37 0.5085 0.9995 1329993 ChemDiv1_005596 O=C1CC(Sc2nc3CCCc3cc2C#N)C(=O)N1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O09 compound treatment 661750.0 70400.0 0.32 666789.0 89400.0 0.44 0.5358 0.9861 1277410 ChemDiv1_005597 CCOc1cccc(c1)c2cc(C(=O)Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O10 compound treatment 673991.0 82600.0 0.37 645734.0 68300.0 0.34 0.5008 0.999 1354984 ChemDiv1_005598 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc(C)ccc3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O11 compound treatment 714806.0 123000.0 0.55 669932.0 92500.0 0.46 0.7148 0.9957 1972935 ChemDiv1_005599 [O-][N+](=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O12 compound treatment 655402.0 64100.0 0.29 616201.0 38800.0 0.19 0.3386 0.981 1972936 ChemDiv1_005600 Cc1cccc(OCCOc2ccc(Cl)cc2C=C3C(=O)NC(=S)NC3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O13 compound treatment 680042.0 88700.0 0.4 670095.0 92700.0 0.46 0.6053 0.9974 1660121 ChemDiv1_005601 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3C(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O14 compound treatment 635291.0 43900.0 0.2 616153.0 38700.0 0.19 0.2747 0.9999 1508109 ChemDiv1_005602 Cn1c(SCc2ccccc2)nc3-c4ccccc4CC5(CCCC5)c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O15 compound treatment 707499.0 116000.0 0.52 671093.0 93700.0 0.46 0.6957 0.9984 1229854 ChemDiv1_005603 COC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)N)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O16 compound treatment 704097.0 113000.0 0.5 647267.0 69800.0 0.35 0.6015 0.983 1217503 ChemDiv1_005604 CCOC(=O)c1ccc(Oc2nc(NC)nc(SC)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O17 compound treatment 756091.0 165000.0 0.74 694688.0 117000.0 0.58 0.9322 0.993 1578995 ChemDiv1_005605 COC(=O)c1sccc1NC(=O)c2cc(nc3ccccc23)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O18 compound treatment 702528.0 111000.0 0.5 676822.0 99400.0 0.49 0.7001 1.0 1972937 ChemDiv1_005606 ClC1=CCC2C(C1)C(=O)N(CC(=O)Nc3sc4CCCCc4c3C#N)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O19 compound treatment 750153.0 159000.0 0.71 689243.0 112000.0 0.55 0.8943 0.9924 1184668 ChemDiv1_005607 COc1cccc(c1)c2cc(C(=O)Nc3ccccc3OC)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O20 compound treatment 694808.0 103000.0 0.46 662330.0 84900.0 0.42 0.6249 0.9988 1972938 ChemDiv1_005608 COc1ccc(NC(=O)c2ccc(cc2)N3C(=O)C4CC=C(Cl)CC4C3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O21 compound treatment 718586.0 127000.0 0.57 665198.0 87800.0 0.43 0.7102 0.9911 1694754 ChemDiv1_005609 NC(=O)c1ccccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O22 compound treatment 677250.0 85900.0 0.38 631417.0 54000.0 0.27 0.461 0.9842 1387249 ChemDiv1_005610 COc1cc(C)nc(n1)N(CC(=O)N)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O23 mock treatment 687716.0 96400.0 0.43 647824.0 70400.0 0.35 0.5516 0.9944 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 O24 mock treatment 410673.0 -181000.0 -0.81 426669.0 -151000.0 -0.75 -1.1 -0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P01 compound treatment 583930.0 -7410.0 -0.03 545578.0 -31900.0 -0.16 -0.1351 -0.8375 1972939 ChemDiv1_005611 COc1ccc(cc1)n2c(SCC=C)nc3sc4COC(C)(C)Cc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P02 compound treatment 634352.0 43000.0 0.19 573800.0 -3640.0 -0.02 0.1234 0.6382 1298888 ChemDiv1_005612 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccccc5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P03 compound treatment 603716.0 12400.0 0.06 565546.0 -11900.0 -0.06 -0.0025 -0.0307 1629242 ChemDiv1_005613 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3nc(cs3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P04 compound treatment 591513.0 170.0 0.0 554355.0 -23100.0 -0.11 -0.0803 -0.7024 1972940 ChemDiv1_005614 CCCCCC(=O)N1C(C2=C(CC(CC2=O)c3cccc(c3)[N+](=O)[O-])Nc4ccccc14)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P05 compound treatment 580745.0 -10600.0 -0.05 552232.0 -25200.0 -0.12 -0.1218 -0.9122 1972941 ChemDiv1_005615 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2ccc(cc2)c3cn4ccccc4n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P06 compound treatment 662626.0 71300.0 0.32 586493.0 9060.0 0.04 0.2574 0.7987 1229490 ChemDiv1_005616 CCN(CC)c1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccccc5)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P07 compound treatment 625951.0 34600.0 0.15 606806.0 29400.0 0.15 0.2124 0.9995 1465144 ChemDiv1_005617 Cc1ccn2c(NC(=O)c3cccs3)c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P08 compound treatment 607896.0 16600.0 0.07 594494.0 17100.0 0.08 0.1121 0.9979 1972942 ChemDiv1_005618 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4c(F)cccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P09 compound treatment 655785.0 64400.0 0.29 598618.0 21200.0 0.1 0.2782 0.9062 1589132 ChemDiv1_005619 COc1ccc2nc(Nc3nc(O)c4ccccc4n3)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P10 compound treatment 636057.0 44700.0 0.2 589561.0 12100.0 0.06 0.184 0.8805 1972943 ChemDiv1_005620 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P11 compound treatment 677226.0 85900.0 0.38 609952.0 32500.0 0.16 0.3857 0.9254 1779873 ChemDiv1_005621 CCC(=O)N1C(C)CC(N(C(=O)c2ccccc2)c3cccc(c3)[N+](=O)[O-])c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P12 compound treatment 636292.0 44900.0 0.2 600141.0 22700.0 0.11 0.2218 0.9622 1972944 ChemDiv1_005622 COc1cccc(C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P13 compound treatment 661123.0 69800.0 0.31 618837.0 41400.0 0.21 0.3659 0.9792 1972945 ChemDiv1_005623 CCCCCCCC(=O)N1C(C)CC(N(C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P14 compound treatment 652569.0 61200.0 0.27 606093.0 28700.0 0.14 0.2942 0.9531 1972946 ChemDiv1_005624 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5c(F)cccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P15 compound treatment 657694.0 66400.0 0.3 620948.0 43500.0 0.22 0.3624 0.9876 1641146 ChemDiv1_005625 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P16 compound treatment 694583.0 103000.0 0.46 626651.0 49200.0 0.24 0.4992 0.9553 1972947 ChemDiv1_005626 COc1cc(cc(OC)c1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P17 compound treatment 688924.0 97600.0 0.44 597384.0 19900.0 0.1 0.3787 0.8457 1539177 ChemDiv1_005627 CC1CC(N(C(=O)C2CC2)c3ccccc3)c4ccccc4N1C(=O)C5CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P18 compound treatment 690225.0 98900.0 0.44 643795.0 66400.0 0.33 0.5454 0.9893 1927909 ChemDiv1_005628 Cn1cnnc1SCC(=O)N2CCCc3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P19 compound treatment 675978.0 84600.0 0.38 620944.0 43500.0 0.22 0.4203 0.9643 1618765 ChemDiv1_005629 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(NS(=O)(=O)C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P20 compound treatment 659514.0 68200.0 0.31 606143.0 28700.0 0.14 0.3163 0.9396 1972948 ChemDiv1_005630 Fc1ccccc1c2nc3ccccc3c(=O)n2NC(=O)c4cc5cc(Br)ccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P21 compound treatment 624097.0 32800.0 0.15 607009.0 29600.0 0.15 0.2073 1.0 1240360 ChemDiv1_005631 COc1ccc(OCC(=O)N(C2CC(C)N(C(=O)COc3ccc(OC)cc3)c4ccccc24)c5ccccc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P22 compound treatment 635441.0 44100.0 0.2 593993.0 16600.0 0.08 0.1976 0.9243 1972949 ChemDiv1_005632 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P23 mock treatment 630257.0 38900.0 0.17 572363.0 -5070.0 -0.03 0.1054 0.5989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.602 P24 mock treatment 411960.0 -179000.0 -0.8 433809.0 -144000.0 -0.71 -1.0709 -0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A01 compound treatment 593281.0 6870.0 0.03 542351.0 -24200.0 -0.12 -0.063 -0.509 1972950 ChemDiv1_005633 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(OC)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A02 compound treatment 559057.0 -27300.0 -0.12 520023.0 -46500.0 -0.23 -0.2495 -0.9562 1605626 ChemDiv1_005634 Oc1ccc(Nc2nc3nonc3nc2Nc4ccc(O)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A03 compound treatment 586140.0 -267.0 0.0 545075.0 -21500.0 -0.11 -0.076 -0.715 1972951 ChemDiv1_005635 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)/C=C/c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A04 compound treatment 579605.0 -6800.0 -0.03 555219.0 -11300.0 -0.06 -0.0612 -0.9588 1369228 ChemDiv1_005636 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A05 compound treatment 609402.0 23000.0 0.1 568810.0 2270.0 0.01 0.0807 0.7796 1189514 ChemDiv1_005637 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc3OCOc3c2)C(=O)Nc4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A06 compound treatment 616354.0 29900.0 0.13 594938.0 28400.0 0.14 0.1943 0.9997 1403900 ChemDiv1_005638 O=C(CSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCC4)cc2s1)NC5CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A07 compound treatment 674928.0 88500.0 0.4 617551.0 51000.0 0.25 0.4589 0.9764 1348397 ChemDiv1_005639 COc1ccc(OC)c(c1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A08 compound treatment 649040.0 62600.0 0.28 600159.0 33600.0 0.17 0.316 0.9691 1918192 ChemDiv1_005640 CCOC(=O)C1=C(N)Oc2c(C1c3cccc(c3)[N+](=O)[O-])c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A09 compound treatment 640266.0 53900.0 0.24 605007.0 38500.0 0.19 0.3052 0.9932 1950303 ChemDiv1_005641 COc1ccc(OC)c(c1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A10 compound treatment 639871.0 53500.0 0.24 609089.0 42500.0 0.21 0.3183 0.998 1972952 ChemDiv1_005642 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)c(OC)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A11 compound treatment 621869.0 35500.0 0.16 596822.0 30300.0 0.15 0.2183 0.9996 1145505 ChemDiv1_005643 Clc1ccc(Oc2ccccc2)c(NC(=O)CSc3nc4ccccc4o3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A12 compound treatment 605280.0 18900.0 0.08 603082.0 36500.0 0.18 0.1877 0.9398 1972953 ChemDiv1_005644 CC(C)(C)c1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A13 compound treatment 635563.0 49200.0 0.22 624558.0 58000.0 0.29 0.3588 0.9913 1972954 ChemDiv1_005645 COc1cc(cc2sc(NC(=O)C3(CC4CC5CC(C4)C3)C5)nc12)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A14 compound treatment 654753.0 68300.0 0.31 631962.0 65400.0 0.32 0.4455 0.9996 1972955 ChemDiv1_005646 CCC1C(=O)N=C(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)N(C1=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A15 compound treatment 670995.0 84600.0 0.38 610852.0 44300.0 0.22 0.423 0.9664 1972956 ChemDiv1_005647 Cc1cc(c(C#N)c(SC2CC(=O)N(C2=O)c3ccccc3)n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A16 compound treatment 619496.0 33100.0 0.15 578136.0 11600.0 0.06 0.1453 0.9149 1947229 ChemDiv1_005648 Nc1nc(SCC(=O)c2ccc(O)c(O)c2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A17 compound treatment 658983.0 72600.0 0.32 615042.0 48500.0 0.24 0.3996 0.989 1972957 ChemDiv1_005649 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)ccc3OC)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A18 compound treatment 648813.0 62400.0 0.28 595907.0 29400.0 0.15 0.3004 0.9537 1609447 ChemDiv1_005650 COC(=O)C1C(C(=C(NC1=O)SCc2cccc3ccccc23)C#N)c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A19 compound treatment 1049562.0 463000.0 2.07 963549.0 397000.0 1.97 2.8567 0.9997 1972958 ChemDiv1_005651 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cc(OC)ccc3OC)c(O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A20 compound treatment 615175.0 28800.0 0.13 575529.0 8990.0 0.04 0.1225 0.8993 1338015 ChemDiv1_005652 CCOC(=O)c1c(C)c(sc1NC(=O)COc2c(F)c(F)cc(F)c2F)C(=O)N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A21 compound treatment 629899.0 43500.0 0.19 577509.0 11000.0 0.05 0.1761 0.8711 1972959 ChemDiv1_005653 COc1cccc(c1)c2nnc(SCC(=O)c3cccs3)n2CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A22 compound treatment 678216.0 91800.0 0.41 628590.0 62000.0 0.31 0.5079 0.9898 1972960 ChemDiv1_005654 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A23 mock treatment 610489.0 24100.0 0.11 544518.0 -22000.0 -0.11 -9.0E-4 -0.006 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 A24 mock treatment 500171.0 -86200.0 -0.39 500454.0 -66100.0 -0.33 -0.5045 -0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B01 compound treatment 634314.0 47900.0 0.21 583475.0 16900.0 0.08 0.2109 0.9161 1226634 ChemDiv1_005655 CCOC(=O)c1c(C)c(sc1NC(=O)C(C)Oc2c(F)c(F)cc(F)c2F)C(=O)N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B02 compound treatment 665387.0 79000.0 0.35 620732.0 54200.0 0.27 0.4398 0.9908 1630339 ChemDiv1_005656 OCCNc1nc(Cl)nc(n1)N2CCC(Cc3ccccc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B03 compound treatment 707967.0 122000.0 0.54 653506.0 87000.0 0.43 0.6894 0.9933 1972961 ChemDiv1_005657 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4c(F)cccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B04 compound treatment 701941.0 116000.0 0.52 639290.0 72700.0 0.36 0.6205 0.9844 1589231 ChemDiv1_005658 Clc1ccccc1N2CC(CC2=O)C(=O)Nc3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B05 compound treatment 728169.0 142000.0 0.63 697571.0 131000.0 0.65 0.9077 0.9999 1174511 ChemDiv1_005659 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B06 compound treatment 724424.0 138000.0 0.62 695630.0 129000.0 0.64 0.889 0.9999 1972962 ChemDiv1_005660 OC(=O)c1ccccc1NC(=O)CN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B07 compound treatment 735138.0 149000.0 0.67 691694.0 125000.0 0.62 0.9092 0.9994 1972963 ChemDiv1_005661 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B08 compound treatment 738350.0 152000.0 0.68 703773.0 137000.0 0.68 0.9616 1.0 1972964 ChemDiv1_005662 CN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B09 compound treatment 730490.0 144000.0 0.64 744516.0 178000.0 0.88 1.0795 0.9882 1972965 ChemDiv1_005663 COc1ccc(cc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B10 compound treatment 701455.0 115000.0 0.51 711040.0 144000.0 0.72 0.8703 0.987 1476095 ChemDiv1_005664 COC(=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B11 compound treatment 731643.0 145000.0 0.65 707266.0 141000.0 0.7 0.9526 0.9994 1972966 ChemDiv1_005665 CC(NC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B12 compound treatment 739596.0 153000.0 0.69 706194.0 140000.0 0.69 0.9741 1.0 1972967 ChemDiv1_005666 CCOc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B13 compound treatment 710930.0 125000.0 0.56 697641.0 131000.0 0.65 0.8534 0.9971 1972968 ChemDiv1_005667 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4C(=O)O)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B14 compound treatment 752096.0 166000.0 0.74 712147.0 146000.0 0.72 1.0345 0.9999 1925921 ChemDiv1_005668 Cc1[n+]([O-])c2ccccc2n(OCC=C)c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B15 compound treatment 762576.0 176000.0 0.79 715554.0 149000.0 0.74 1.0796 0.9995 1341470 ChemDiv1_005669 Fc1cccc(Nc2nc3nonc3nc2Nc4cccc(F)c4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B16 compound treatment 731160.0 145000.0 0.65 721234.0 155000.0 0.77 1.0 0.9965 1338300 ChemDiv1_005670 Fc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B17 compound treatment 787966.0 202000.0 0.9 737498.0 171000.0 0.85 1.2368 0.9995 1972969 ChemDiv1_005671 CCC(C)Nc1nc(OCC(F)(F)F)nc(OCC(F)(F)F)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B18 compound treatment 745569.0 159000.0 0.71 704529.0 138000.0 0.68 0.9871 0.9998 1671762 ChemDiv1_005672 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B19 compound treatment 727264.0 141000.0 0.63 713580.0 147000.0 0.73 0.9609 0.9974 1684053 ChemDiv1_005673 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cccc(OC(=O)c4ccco4)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B20 compound treatment 721014.0 135000.0 0.6 678230.0 112000.0 0.55 0.8173 0.9991 1478373 ChemDiv1_005674 COc1cccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B21 compound treatment 742436.0 156000.0 0.7 699858.0 133000.0 0.66 0.9609 0.9996 1972970 ChemDiv1_005675 CCS(=O)(=O)c1ccc2nc(SCc3ccccc3Cl)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B22 compound treatment 702202.0 116000.0 0.52 663683.0 97100.0 0.48 0.7068 0.9993 1972971 ChemDiv1_005676 CC(C)N1C(=O)/C(=C\c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])/c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B23 mock treatment 699472.0 113000.0 0.51 676870.0 110000.0 0.55 0.7443 0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 B24 mock treatment 504317.0 -82100.0 -0.37 517236.0 -49300.0 -0.24 -0.4326 -0.9803 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C01 compound treatment 640559.0 54200.0 0.24 571990.0 5450.0 0.03 0.1905 0.781 1972972 ChemDiv1_005677 Cc1nn(CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)c(C)c1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C02 compound treatment 665437.0 79000.0 0.35 593747.0 27200.0 0.13 0.3454 0.9125 1559918 ChemDiv1_005678 CCCCN(CN1C(=O)C2C3CC(C=C3)C2C1=O)CN4C(=O)C5C6CC(C=C6)C5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C03 compound treatment 706635.0 120000.0 0.54 653834.0 87300.0 0.43 0.6863 0.9941 1334069 ChemDiv1_005679 CC(C)(C)c1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C04 compound treatment 722423.0 136000.0 0.61 657640.0 91100.0 0.45 0.7496 0.9891 1972973 ChemDiv1_005680 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(o3)c4ccccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C05 compound treatment 710935.0 125000.0 0.56 615765.0 49200.0 0.24 0.5666 0.9312 1950530 ChemDiv1_005681 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C06 compound treatment 688555.0 102000.0 0.46 633169.0 66600.0 0.33 0.5567 0.9872 1170129 ChemDiv1_005682 O=C(CSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCC4)cc2s1)NC5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C07 compound treatment 692996.0 107000.0 0.48 685814.0 119000.0 0.59 0.7552 0.9944 1318531 ChemDiv1_005683 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C08 compound treatment 754005.0 168000.0 0.75 676870.0 110000.0 0.55 0.917 0.9879 1972974 ChemDiv1_005684 COc1cc(cc(Br)c1OC)C2C(=C(N)OC3=C2C(=O)CCC3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C09 compound treatment 733779.0 147000.0 0.66 698419.0 132000.0 0.65 0.9284 1.0 1972975 ChemDiv1_005685 CCOc1ccccc1N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C10 compound treatment 706686.0 120000.0 0.54 689288.0 123000.0 0.61 0.8107 0.9982 1721036 ChemDiv1_005686 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CCC4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C11 compound treatment 751509.0 165000.0 0.74 702170.0 136000.0 0.67 0.9977 0.9989 1972976 ChemDiv1_005687 CCCC/1=NN(C(=O)\C1=C(\C)/Nc2cc(Cl)ccc2O)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C12 compound treatment 708805.0 122000.0 0.55 676984.0 110000.0 0.55 0.7743 1.0 1685915 ChemDiv1_005688 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)C(C)(C)C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C13 compound treatment 1031817.0 445000.0 1.99 1009290.0 443000.0 2.19 2.9607 0.9989 1972977 ChemDiv1_005689 CN(C)c1ccc(/C=C/2\Sc3c(ccc4ccccc34)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C14 compound treatment 777496.0 191000.0 0.86 744843.0 178000.0 0.88 1.2294 0.9999 1972978 ChemDiv1_005690 CCC1C(=O)N=C(SCC(=O)Nc2ccc(C)cc2)N(C1=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C15 compound treatment 787761.0 201000.0 0.9 745459.0 179000.0 0.89 1.2641 1.0 1946889 ChemDiv1_005691 COc1ccc2[nH]c(SCC(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C16 compound treatment 1471105.0 885000.0 3.96 1688087.0 1120000.0 5.56 6.7289 0.9862 1704015 ChemDiv1_005692 Oc1ccc(cc1O)C(=O)CSc2nc(ccc2C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C17 compound treatment 771071.0 185000.0 0.83 702206.0 136000.0 0.67 1.0597 0.9947 1972979 ChemDiv1_005693 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(C)c3)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C18 compound treatment 712331.0 126000.0 0.56 642141.0 75600.0 0.37 0.6634 0.9803 1511119 ChemDiv1_005694 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccc(Cl)cc2)C(=O)OC(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C19 compound treatment 728714.0 142000.0 0.64 683502.0 117000.0 0.58 0.8601 0.9989 1972980 ChemDiv1_005695 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(cc3)C4C(=C(N)Oc5[nH]nc(CCC)c45)C#N)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C20 compound treatment 743426.0 157000.0 0.7 648137.0 81600.0 0.4 0.7828 0.9655 1972981 ChemDiv1_005696 COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C21 compound treatment 741141.0 155000.0 0.69 691947.0 125000.0 0.62 0.929 0.9985 1741305 ChemDiv1_005697 Cc1c(Nc2nc3nonc3nc2Nc4ccc(C)cc4C)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C22 compound treatment 710773.0 124000.0 0.56 627613.0 61100.0 0.3 0.6076 0.9589 1972982 ChemDiv1_005698 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C23 mock treatment 722250.0 136000.0 0.61 609528.0 43000.0 0.21 0.5806 0.9011 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 C24 mock treatment 323572.0 -263000.0 -1.18 502265.0 -64300.0 -0.32 -1.0571 -0.8673 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D01 compound treatment 697893.0 111000.0 0.5 637584.0 71000.0 0.35 0.6017 0.9854 1706606 ChemDiv1_005699 NC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D02 compound treatment 668938.0 82500.0 0.37 639888.0 73300.0 0.36 0.5182 1.0 1364384 ChemDiv1_005700 Cc1cccc(Nc2nc(NCc3ccco3)nc(n2)N4CCOCC4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D03 compound treatment 717459.0 131000.0 0.59 687902.0 121000.0 0.6 0.8399 0.9999 1637238 ChemDiv1_005701 Clc1cc(nc(n1)N2CCOCC2)N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D04 compound treatment 711166.0 125000.0 0.56 676329.0 110000.0 0.54 0.7795 0.9999 1972983 ChemDiv1_005702 Clc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(Br)cc3)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D05 compound treatment 769994.0 184000.0 0.82 726355.0 160000.0 0.79 1.1409 0.9998 1231438 ChemDiv1_005703 CCOc1ccc(NC(=O)c2sc3nc(N)c(C#N)c(c4ccc(OC)c(OC)c4)c3c2N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D06 compound treatment 703086.0 117000.0 0.52 692191.0 126000.0 0.62 0.8094 0.9962 1972984 ChemDiv1_005704 [O-][N+](=O)c1ccccc1NC(=O)CN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D07 compound treatment 738854.0 152000.0 0.68 727851.0 161000.0 0.8 1.0476 0.9969 1972985 ChemDiv1_005705 CC1SC2(N(C1=O)c3ccc(Br)cc3)C(=O)Nc4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D08 compound treatment 731415.0 145000.0 0.65 725007.0 158000.0 0.78 1.0141 0.9955 1972986 ChemDiv1_005706 FC(F)(F)c1oc2cc(OC(=O)c3ccco3)ccc2c(=O)c1Oc4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D09 compound treatment 766775.0 180000.0 0.81 737082.0 171000.0 0.84 1.1683 0.9997 1972987 ChemDiv1_005707 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D10 compound treatment 743735.0 157000.0 0.7 712284.0 146000.0 0.72 1.0085 0.9999 1171304 ChemDiv1_005708 CCOC(=O)c1ccc(Nc2ncnc3ccc(Br)cc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D11 compound treatment 759226.0 173000.0 0.77 750358.0 184000.0 0.91 1.1909 0.9967 1397851 ChemDiv1_005709 CSc1nc2ccccc2n1CC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D12 compound treatment 706603.0 120000.0 0.54 691115.0 125000.0 0.62 0.8168 0.9977 1924036 ChemDiv1_005710 CCc1ccc(/C=C/2\N(C(=O)C)C(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D13 compound treatment 750598.0 164000.0 0.73 705730.0 139000.0 0.69 1.0073 0.9995 1666837 ChemDiv1_005711 Cc1ccc(cc1)C(=O)c2oc3ccccc3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D14 compound treatment 786836.0 200000.0 0.9 730021.0 163000.0 0.81 1.2071 0.9987 1784510 ChemDiv1_005712 CCOC(=O)COn1c(=O)c(C)[n+]([O-])c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D15 compound treatment 799399.0 213000.0 0.95 774059.0 208000.0 1.03 1.4011 0.9993 1397390 ChemDiv1_005713 Cc1ccc(Nc2nc3nonc3nc2N4CCCCC4)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D16 compound treatment 712158.0 126000.0 0.56 704534.0 138000.0 0.68 0.8814 0.9953 1589310 ChemDiv1_005714 CN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D17 compound treatment 758856.0 172000.0 0.77 729828.0 163000.0 0.81 1.1178 0.9997 1972988 ChemDiv1_005715 CC(C)(C)Nc1nc(OCC(F)(F)F)nc(OCC(F)(F)F)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D18 compound treatment 721499.0 135000.0 0.6 704210.0 138000.0 0.68 0.9098 0.9982 1386024 ChemDiv1_005716 COc1ccccc1n2c(SC)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D19 compound treatment 767562.0 181000.0 0.81 736445.0 170000.0 0.84 1.1685 0.9998 1282415 ChemDiv1_005717 NC1=C(C#N)C2(C(=O)N(C(=O)c3ccccc3Cl)c4ccccc42)C5=C(CCCC5=O)O1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D20 compound treatment 751931.0 166000.0 0.74 719884.0 153000.0 0.76 1.0611 0.9999 1572075 ChemDiv1_005718 CCOC(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D21 compound treatment 763758.0 177000.0 0.79 740862.0 174000.0 0.86 1.172 0.9991 1972989 ChemDiv1_005719 CCOc1c(OC)cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D22 compound treatment 743173.0 157000.0 0.7 713559.0 147000.0 0.73 1.0112 0.9998 1972990 ChemDiv1_005720 CCN1C(=O)/C(=C/c2nc3ccccc3c(=O)n2c4ccccc4[N+](=O)[O-])/c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D23 mock treatment 722862.0 136000.0 0.61 688320.0 122000.0 0.6 0.8585 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 D24 mock treatment 298164.0 -288000.0 -1.29 524140.0 -42400.0 -0.21 -1.0609 -0.8115 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E01 compound treatment 637347.0 50900.0 0.23 569002.0 2460.0 0.01 0.1699 0.7438 1331756 ChemDiv1_005721 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E02 compound treatment 663460.0 77100.0 0.34 606563.0 40000.0 0.2 0.3841 0.9654 1972991 ChemDiv1_005722 CCCCSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E03 compound treatment 699848.0 113000.0 0.51 674159.0 108000.0 0.53 0.736 0.9997 1972992 ChemDiv1_005723 CCCCOc1ccc(cc1)C(=O)On2c(C)nc3ccccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E04 compound treatment 690170.0 104000.0 0.46 654610.0 88100.0 0.44 0.6369 0.9995 1159523 ChemDiv1_005724 CCn1c(NC(=O)c2cccs2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E05 compound treatment 729121.0 143000.0 0.64 694108.0 128000.0 0.63 0.8986 1.0 1381269 ChemDiv1_005725 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(F)c2)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E06 compound treatment 713961.0 128000.0 0.57 659402.0 92900.0 0.46 0.729 0.9943 1972993 ChemDiv1_005726 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccc4nc(SCC(=O)NCC5CCCO5)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E07 compound treatment 718587.0 132000.0 0.59 713955.0 147000.0 0.73 0.9348 0.9946 1304345 ChemDiv1_005727 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccc(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E08 compound treatment 735677.0 149000.0 0.67 700600.0 134000.0 0.66 0.9421 1.0 1972994 ChemDiv1_005728 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E09 compound treatment 757010.0 171000.0 0.76 720906.0 154000.0 0.76 1.0807 1.0 1972995 ChemDiv1_005729 CCC(=O)OC1=C(C)C2C3C(C(=O)N(C3=O)c4ccc(F)cc4)C1(C)C5C2C(=O)N(C5=O)c6ccc(F)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E10 compound treatment 737391.0 151000.0 0.68 701506.0 135000.0 0.67 0.9507 1.0 1151783 ChemDiv1_005730 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccccc3OC(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E11 compound treatment 746042.0 160000.0 0.71 727911.0 161000.0 0.8 1.0705 0.9984 1972996 ChemDiv1_005731 CCCC/1=NN(C(=O)\C1=C(/C)\Nc2cccc(F)c2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E12 compound treatment 723295.0 137000.0 0.61 705064.0 139000.0 0.69 0.9185 0.9984 1972997 ChemDiv1_005732 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)N(C(=O)c4ccccc4)c5ccccc53)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E13 compound treatment 739426.0 153000.0 0.68 717592.0 151000.0 0.75 1.0135 0.999 1972998 ChemDiv1_005733 [O-][N+](=O)c1csc(NC(=O)c2cc3ccccc3o2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E14 compound treatment 771904.0 185000.0 0.83 728798.0 162000.0 0.8 1.1555 0.9999 1972999 ChemDiv1_005734 CC(C)Cc1c(C#N)c(N)nc(SCC(=O)c2cc3cc(Br)ccc3oc2=O)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E15 compound treatment 809710.0 223000.0 1.0 764509.0 198000.0 0.98 1.4003 1.0 1690001 ChemDiv1_005735 Cc1ccc2cccc(SCc3nc(N)nc(Nc4ccccc4)n3)c2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E16 compound treatment 780496.0 194000.0 0.87 732687.0 166000.0 0.82 1.1963 0.9996 1973000 ChemDiv1_005736 O=C1NC(=C(C#N)C2(CCCCC2)C1C#N)SCCCCSC3=C(C#N)C4(CCCCC4)C(C#N)C(=O)N3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E17 compound treatment 779809.0 193000.0 0.87 731072.0 165000.0 0.82 1.1885 0.9995 1973001 ChemDiv1_005737 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3ccc(OC)cc3OC)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E18 compound treatment 736801.0 150000.0 0.67 708331.0 142000.0 0.7 0.9727 0.9998 1544101 ChemDiv1_005738 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E19 compound treatment 746729.0 160000.0 0.72 727226.0 161000.0 0.8 1.0703 0.9987 1973002 ChemDiv1_005739 CCCCNc1nc(Nc2ccc(Cl)cc2)nc(n1)N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E20 compound treatment 741540.0 155000.0 0.69 701772.0 135000.0 0.67 0.9647 0.9998 1973003 ChemDiv1_005740 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E21 compound treatment 765127.0 179000.0 0.8 719964.0 153000.0 0.76 1.1031 0.9997 1274934 ChemDiv1_005741 Cc1nccn1c2nc3nonc3nc2Nc4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E22 compound treatment 723919.0 138000.0 0.62 695334.0 129000.0 0.64 0.8864 0.9998 1973004 ChemDiv1_005742 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E23 mock treatment 739908.0 154000.0 0.69 689037.0 122000.0 0.61 0.915 0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 E24 mock treatment 218611.0 -368000.0 -1.65 512719.0 -53800.0 -0.27 -1.3527 -0.8111 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F01 compound treatment 655522.0 69100.0 0.31 606990.0 40400.0 0.2 0.3604 0.9779 1487742 ChemDiv1_005743 NC(=O)c1c(NC(=O)CSc2nc3ccccc3o2)sc4CCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F02 compound treatment 671864.0 85500.0 0.38 642329.0 75800.0 0.38 0.536 1.0 1154675 ChemDiv1_005744 CCc1nnc(SCC(=O)Nc2nncs2)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F03 compound treatment 713685.0 127000.0 0.57 687951.0 121000.0 0.6 0.8281 0.9996 1392623 ChemDiv1_005745 CCCC(=O)Oc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F04 compound treatment 711412.0 125000.0 0.56 686634.0 120000.0 0.59 0.8163 0.9995 1524851 ChemDiv1_005746 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OC(=O)c4ccccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F05 compound treatment 748362.0 162000.0 0.72 724658.0 158000.0 0.78 1.0665 0.9993 1689008 ChemDiv1_005747 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F06 compound treatment 749973.0 164000.0 0.73 724778.0 158000.0 0.78 1.072 0.9994 1923569 ChemDiv1_005748 OCCN(C(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F07 compound treatment 720394.0 134000.0 0.6 735721.0 169000.0 0.84 1.0167 0.9865 1973005 ChemDiv1_005749 CN1C(=O)N(C)C(=O)C(=Cc2ccc(N3CCN(CC3)C(=O)c4ccccc4)c(c2)[N+](=O)[O-])C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F08 compound treatment 795024.0 209000.0 0.93 767525.0 201000.0 1.0 1.3643 0.9995 1973006 ChemDiv1_005750 CCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F09 compound treatment 727840.0 141000.0 0.63 724778.0 158000.0 0.78 1.002 0.9944 1973007 ChemDiv1_005751 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(cc4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F10 compound treatment 719379.0 133000.0 0.6 732704.0 166000.0 0.82 1.0029 0.9873 1312514 ChemDiv1_005752 Brc1ccc2ncnc(NCCN3CCOCC3)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F11 compound treatment 751112.0 165000.0 0.74 756394.0 190000.0 0.94 1.1864 0.9927 1261546 ChemDiv1_005753 Cn1c(Sc2ncnn2CC(=O)NC(C)(C)C)nc3n(C)c(=O)n(C)c(=O)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F12 compound treatment 815025.0 229000.0 1.02 799147.0 233000.0 1.15 1.5384 0.9982 1784110 ChemDiv1_005754 NS(=O)(=O)c1ccc(cc1)N2N=C(CC2c3ccccc3)/C=C/c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F13 compound treatment 770948.0 185000.0 0.83 759836.0 193000.0 0.96 1.2612 0.9973 1973008 ChemDiv1_005755 CCN(CC)CCCC(C)N/C(=C/1\C(=O)NC(=O)N(C1=O)c2ccc(OC)cc2)/CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F14 compound treatment 1390679.0 804000.0 3.6 1557098.0 991000.0 4.91 6.0155 0.9884 1784511 ChemDiv1_005756 [O-][n+]1cc(=O)n(OCc2ccccc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F15 compound treatment 787825.0 201000.0 0.9 753852.0 187000.0 0.93 1.2937 0.9999 1118666 ChemDiv1_005757 CC1CC(C)CN(C1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F16 compound treatment 754235.0 168000.0 0.75 707894.0 141000.0 0.7 1.0264 0.9994 1483149 ChemDiv1_005758 COC(=O)CCNc1nc(nc2ccccc12)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F17 compound treatment 758565.0 172000.0 0.77 740612.0 174000.0 0.86 1.1547 0.9984 1973009 ChemDiv1_005759 CC(C)OC(=O)CSc1nc2CCCc2c(C3CCC=CC3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F18 compound treatment 738452.0 152000.0 0.68 690127.0 124000.0 0.61 0.9142 0.9986 1973010 ChemDiv1_005760 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F19 compound treatment 723403.0 137000.0 0.61 702482.0 136000.0 0.67 0.9098 0.9989 1973011 ChemDiv1_005761 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5cccc(c5)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F20 compound treatment 746885.0 160000.0 0.72 730021.0 163000.0 0.81 1.0806 0.9982 1367796 ChemDiv1_005762 CCCOC(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F21 compound treatment 884053.0 298000.0 1.33 849776.0 283000.0 1.4 1.9343 0.9997 1523650 ChemDiv1_005763 Nc1nc2nonc2nc1N3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F22 compound treatment 736013.0 150000.0 0.67 693160.0 127000.0 0.63 0.9171 0.9995 1935860 ChemDiv1_005764 CCCN1C(=O)/C(=C/c2nc3ccccc3c(=O)n2c4ccccc4[N+](=O)[O-])/c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F23 mock treatment 722406.0 136000.0 0.61 674650.0 108000.0 0.54 0.8092 0.998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 F24 mock treatment 504892.0 -81500.0 -0.36 516961.0 -49600.0 -0.25 -0.4317 -0.9814 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G01 compound treatment 632658.0 46300.0 0.21 567335.0 791.0 0.0 0.1492 0.7204 1973012 ChemDiv1_005765 Cc1cc(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G02 compound treatment 656463.0 70100.0 0.31 616701.0 50200.0 0.25 0.3974 0.9934 1973013 ChemDiv1_005766 COc1cccc(c1)n2c(/C=C/3\C(=O)N(C(C)C)c4ccccc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G03 compound treatment 728411.0 142000.0 0.64 675363.0 109000.0 0.54 0.8307 0.9966 1612220 ChemDiv1_005767 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)COc4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G04 compound treatment 749967.0 164000.0 0.73 670720.0 104000.0 0.52 0.8826 0.9853 1973014 ChemDiv1_005768 CC(=O)Nc1nc2cc(C)c(C)cc2[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G05 compound treatment 739148.0 153000.0 0.68 685668.0 119000.0 0.59 0.9007 0.9973 1973015 ChemDiv1_005769 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G06 compound treatment 729221.0 143000.0 0.64 678278.0 112000.0 0.55 0.8434 0.9974 1973016 ChemDiv1_005770 COC(=O)c1ccccc1NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccc(cc5C4=O)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G07 compound treatment 691933.0 106000.0 0.47 692062.0 126000.0 0.62 0.7737 0.9908 1950457 ChemDiv1_005771 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G08 compound treatment 745010.0 159000.0 0.71 708211.0 142000.0 0.7 0.9983 1.0 1131464 ChemDiv1_005772 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccccc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G09 compound treatment 784150.0 198000.0 0.89 719610.0 153000.0 0.76 1.1621 0.997 1973017 ChemDiv1_005773 CCC(=O)OC1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4F)C1(C)C5C2C(=O)N(C5=O)c6ccccc6F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G10 compound treatment 714685.0 128000.0 0.57 710915.0 144000.0 0.72 0.9118 0.9941 1155684 ChemDiv1_005774 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3OC(=O)N4CCOCC4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G11 compound treatment 742693.0 156000.0 0.7 721855.0 155000.0 0.77 1.0387 0.9989 1973018 ChemDiv1_005775 CCCN/C(=C\1/C(=O)N(N=C1CCC)c2nc3ccccc3s2)/C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G12 compound treatment 730464.0 144000.0 0.64 701501.0 135000.0 0.67 0.9287 0.9998 1289583 ChemDiv1_005776 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)c4ccccc4Cl)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G13 compound treatment 859404.0 273000.0 1.22 788115.0 222000.0 1.1 1.6402 0.9986 1973019 ChemDiv1_005777 O=C1/C(=C/2\Sc3ccccc3C2=O)/Nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G14 compound treatment 763765.0 177000.0 0.79 700574.0 134000.0 0.66 1.0309 0.9961 1973020 ChemDiv1_005778 CCOC(=O)C1=C(N)OC2=C(C1C3CCCCC3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G15 compound treatment 794226.0 208000.0 0.93 730690.0 164000.0 0.81 1.2328 0.9978 1973021 ChemDiv1_005779 O=C(NCCc1ccc(cc1)S(=O)(=O)N2CCCCC2)c3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G16 compound treatment 770499.0 184000.0 0.82 715082.0 149000.0 0.74 1.103 0.9984 1256563 ChemDiv1_005780 CC(=Cc1ccc(C#N)c(SCC(=O)c2cc3ccccc3oc2=O)n1)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G17 compound treatment 797581.0 211000.0 0.95 726236.0 160000.0 0.79 1.2278 0.9961 1973022 ChemDiv1_005781 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G18 compound treatment 779689.0 193000.0 0.87 707608.0 141000.0 0.7 1.1059 0.9944 1121954 ChemDiv1_005782 CSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G19 compound treatment 790685.0 204000.0 0.91 732210.0 166000.0 0.82 1.2269 0.9985 1742540 ChemDiv1_005783 C1CN(CCO1)c2nc(Nc3ccccc3)nc(Nc4ccccc4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G20 compound treatment 720734.0 134000.0 0.6 676111.0 110000.0 0.54 0.809 0.9987 1973023 ChemDiv1_005784 COc1cccc(c1)N2C(=O)/C(=C/c3c(OC)ccc4ccccc34)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G21 compound treatment 754424.0 168000.0 0.75 719100.0 153000.0 0.76 1.0662 1.0 1704844 ChemDiv1_005785 C1CCN(C1)c2nc3nonc3nc2N4CCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G22 compound treatment 750101.0 164000.0 0.73 697429.0 131000.0 0.65 0.9766 0.9981 1973024 ChemDiv1_005786 CC1C(=O)N(C(c2ccc(Br)cc2)S1(=O)=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G23 mock treatment 751509.0 165000.0 0.74 689613.0 123000.0 0.61 0.9537 0.9954 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 G24 mock treatment 314778.0 -272000.0 -1.22 523901.0 -42600.0 -0.21 -1.0092 -0.8177 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H01 compound treatment 623037.0 36600.0 0.16 587632.0 21100.0 0.1 0.1898 0.9763 1973025 ChemDiv1_005787 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(Br)cc3)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H02 compound treatment 674716.0 88300.0 0.4 637684.0 71100.0 0.35 0.5287 0.9984 1973026 ChemDiv1_005788 CCn1c(SCc2nc3ccc(cc3[nH]2)[N+](=O)[O-])nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H03 compound treatment 720513.0 134000.0 0.6 679966.0 113000.0 0.56 0.8218 0.9995 1973027 ChemDiv1_005789 COc1ccc(cc1)C(=O)CSc2nc(N)c(C#N)c(C3CCCCC3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H04 compound treatment 695469.0 109000.0 0.49 666048.0 99500.0 0.49 0.6938 1.0 1973028 ChemDiv1_005790 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccc(N4CCOCC4)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H05 compound treatment 737273.0 151000.0 0.68 699909.0 133000.0 0.66 0.9447 0.9999 1784759 ChemDiv1_005791 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H06 compound treatment 692613.0 106000.0 0.48 675670.0 109000.0 0.54 0.7184 0.9979 1973029 ChemDiv1_005792 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H07 compound treatment 699508.0 113000.0 0.51 728076.0 162000.0 0.8 0.9238 0.9756 1973030 ChemDiv1_005793 Cc1c(NC(=O)CSc2nc[nH]n2)c(=O)n(c3ccccc3)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H08 compound treatment 751334.0 165000.0 0.74 757111.0 191000.0 0.94 1.1896 0.9926 1941426 ChemDiv1_005794 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H09 compound treatment 733222.0 147000.0 0.66 751352.0 185000.0 0.92 1.1121 0.9868 1973031 ChemDiv1_005795 COc1ccc(OC)c(c1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H10 compound treatment 719229.0 133000.0 0.59 740862.0 174000.0 0.86 1.031 0.9834 1617513 ChemDiv1_005796 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H11 compound treatment 718667.0 132000.0 0.59 697404.0 131000.0 0.65 0.877 0.999 1205726 ChemDiv1_005797 CCN(CC)CCn1c(NC(=O)COc2c(F)c(F)cc(F)c2F)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H12 compound treatment 3343191.0 2760000.0 12.34 3932067.0 3370000.0 16.67 20.515 0.989 1425860 ChemDiv1_005798 CN(C)c1ccc(C=c2sc3=NC(=C(C(c4ccc(C)o4)n3c2=O)C(=O)Nc5ccccc5)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H13 compound treatment 725973.0 140000.0 0.62 715941.0 149000.0 0.74 0.9651 0.9964 1973032 ChemDiv1_005799 [O-][N+](=O)c1ccc(cc1)C(C2C(=O)NC(=S)N(C2=O)c3ccccc3)C4C(=O)NC(=S)N(C4=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H14 compound treatment 1245303.0 659000.0 2.95 1329195.0 763000.0 3.78 4.7571 0.9925 1973033 ChemDiv1_005800 CCOn1c(=O)c[n+]([O-])c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H15 compound treatment 745615.0 159000.0 0.71 755233.0 189000.0 0.93 1.1649 0.991 1589086 ChemDiv1_005801 C1Oc2ccc(Nc3nc4nonc4nc3N5CCOCC5)cc2O1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H16 compound treatment 708217.0 122000.0 0.55 715788.0 149000.0 0.74 0.9083 0.9888 1973034 ChemDiv1_005802 O=C(CN1C(=O)C2CCC(=O)CC2C1=O)N3CCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H17 compound treatment 768791.0 182000.0 0.82 756381.0 190000.0 0.94 1.2423 0.9975 1973035 ChemDiv1_005803 Nc1nc(SCC(=O)Nc2ccc([N+](=O)[O-])c3ccccc23)c(C#N)c(c4ccco4)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H18 compound treatment 693529.0 107000.0 0.48 690937.0 124000.0 0.62 0.7748 0.9923 1973036 ChemDiv1_005804 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H19 compound treatment 747295.0 161000.0 0.72 728979.0 162000.0 0.8 1.0782 0.9985 1973037 ChemDiv1_005805 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C4(C(=O)Nc5ccc(Br)cc54)c23)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H20 compound treatment 737200.0 151000.0 0.68 715141.0 149000.0 0.74 0.9978 0.9991 1335779 ChemDiv1_005806 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H21 compound treatment 753435.0 167000.0 0.75 724523.0 158000.0 0.78 1.0821 0.9997 1180045 ChemDiv1_005807 COc1ccc(Cl)cc1Nc2nc3nonc3nc2Nc4cc(Cl)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H22 compound treatment 735317.0 149000.0 0.67 713301.0 147000.0 0.73 0.9854 0.9991 1973038 ChemDiv1_005808 COc1ccccc1n2c(/C=C/3\C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H23 mock treatment 726814.0 140000.0 0.63 681406.0 115000.0 0.57 0.8468 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 H24 mock treatment 489388.0 -97000.0 -0.43 534027.0 -32500.0 -0.16 -0.421 -0.9089 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I01 compound treatment 643958.0 57600.0 0.26 573496.0 6950.0 0.03 0.2065 0.7946 1973039 ChemDiv1_005809 COc1cc(/C=C\C(=O)Nn2c(nc3ccccc3c2=O)c4cccc(Cl)c4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I02 compound treatment 669093.0 82700.0 0.37 621728.0 55200.0 0.27 0.455 0.9889 1973040 ChemDiv1_005810 COc1cccc(c1)n2c(/C=C/3\C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I03 compound treatment 732559.0 146000.0 0.65 668044.0 102000.0 0.5 0.8182 0.9915 1516615 ChemDiv1_005811 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I04 compound treatment 732215.0 146000.0 0.65 665162.0 98600.0 0.49 0.807 0.9898 1724015 ChemDiv1_005812 CCN(CC)CCNc1nc2nonc2nc1NCCN(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I05 compound treatment 743586.0 157000.0 0.7 670859.0 104000.0 0.52 0.8629 0.9885 1950576 ChemDiv1_005813 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I06 compound treatment 744941.0 159000.0 0.71 653276.0 86700.0 0.43 0.8056 0.9711 1453232 ChemDiv1_005814 CCn1c(SCC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)nc4n(C)c(=O)n(C)c(=O)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I07 compound treatment 759657.0 173000.0 0.78 681941.0 115000.0 0.57 0.9526 0.9887 1382081 ChemDiv1_005815 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I08 compound treatment 742985.0 157000.0 0.7 686229.0 120000.0 0.59 0.9149 0.9965 1407405 ChemDiv1_005816 Cn1c(=O)n(C)c2ncn(CC(=O)NCc3ccccc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I09 compound treatment 783252.0 197000.0 0.88 716245.0 150000.0 0.74 1.1475 0.9963 1973041 ChemDiv1_005817 CCOC(=O)C1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4C)C1(C)C5C2C(=O)N(C5=O)c6ccccc6C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I10 compound treatment 730226.0 144000.0 0.64 718897.0 152000.0 0.75 0.9889 0.9969 1604905 ChemDiv1_005818 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I11 compound treatment 752042.0 166000.0 0.74 723653.0 157000.0 0.78 1.0746 0.9997 1973042 ChemDiv1_005819 CCCC/1=NN(C(=O)\C1=C(\C)/N2CCOCC2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I12 compound treatment 699376.0 113000.0 0.51 676148.0 110000.0 0.54 0.7415 0.9994 1973043 ChemDiv1_005820 Cn1cnnc1SCC(=O)NC2=NCCS2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I13 compound treatment 744159.0 158000.0 0.71 697819.0 131000.0 0.65 0.9592 0.9992 1528228 ChemDiv1_005821 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCC(=O)N5CCCCC5)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I14 compound treatment 766952.0 181000.0 0.81 696885.0 130000.0 0.65 1.028 0.9938 1948361 ChemDiv1_005822 COc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(O)c(O)c3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I15 compound treatment 768381.0 182000.0 0.81 714483.0 148000.0 0.73 1.0942 0.9986 1618722 ChemDiv1_005823 COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(n2)N4CCNCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I16 compound treatment 765157.0 179000.0 0.8 710270.0 144000.0 0.71 1.0692 0.9983 1187099 ChemDiv1_005824 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCc3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I17 compound treatment 751509.0 165000.0 0.74 730834.0 164000.0 0.81 1.0981 0.9988 1973044 ChemDiv1_005825 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc4OCOc4cc3[N+](=O)[O-])/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I18 compound treatment 739767.0 153000.0 0.69 688732.0 122000.0 0.61 0.9134 0.998 1351712 ChemDiv1_005826 CCOC(=O)C1=C(C)NC(=C(C#N)C1CC(C)C)SCC(=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I19 compound treatment 760310.0 174000.0 0.78 710989.0 144000.0 0.72 1.0564 0.9991 1973045 ChemDiv1_005827 COc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I20 compound treatment 725645.0 139000.0 0.62 703142.0 137000.0 0.68 0.9192 0.9992 1973046 ChemDiv1_005828 COc1cccc(c1)N2C(=O)/C(=C/c3ccc(OC)c4ccccc34)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I21 compound treatment 774481.0 188000.0 0.84 713891.0 147000.0 0.73 1.1114 0.9975 1973047 ChemDiv1_005829 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccco3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I22 compound treatment 740209.0 154000.0 0.69 705777.0 139000.0 0.69 0.9745 1.0 1661310 ChemDiv1_005830 CC1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)c(C)c4)c5ccccc25)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I23 mock treatment 747596.0 161000.0 0.72 688142.0 122000.0 0.6 0.9362 0.996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 I24 mock treatment 325435.0 -261000.0 -1.17 504181.0 -62400.0 -0.31 -1.0445 -0.8644 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J01 compound treatment 623162.0 36800.0 0.16 594351.0 27800.0 0.14 0.2137 0.9961 1973048 ChemDiv1_005831 CN1C(=O)N(C)C(=O)C(=Cc2ccc(N3CCc4ccccc4C3)c(c2)[N+](=O)[O-])C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J02 compound treatment 680009.0 93600.0 0.42 639489.0 72900.0 0.36 0.5518 0.9973 1264957 ChemDiv1_005832 Cn1c(SCc2nc3ccccc3n2CC(=O)N)nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J03 compound treatment 562345.0 -24100.0 -0.11 526528.0 -40000.0 -0.2 -0.2163 -0.9589 1384870 ChemDiv1_005833 Nc1nc(SCc2ccccc2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J04 compound treatment 687456.0 101000.0 0.45 662271.0 95700.0 0.47 0.6552 0.9997 1973049 ChemDiv1_005834 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(N4CCOCC4)c(c3)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J05 compound treatment 737657.0 151000.0 0.68 699954.0 133000.0 0.66 0.9461 0.9999 1784758 ChemDiv1_005835 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J06 compound treatment 727291.0 141000.0 0.63 736159.0 170000.0 0.84 1.0401 0.99 1973050 ChemDiv1_005836 CCOc1ccccc1NC(=O)CN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J07 compound treatment 733668.0 147000.0 0.66 717048.0 151000.0 0.75 0.9933 0.9981 1144035 ChemDiv1_005837 COc1cc(cc(OC)c1OC)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J08 compound treatment 736492.0 150000.0 0.67 718362.0 152000.0 0.75 1.0069 0.9984 1950341 ChemDiv1_005838 CC1CN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Br)c(oc23)C(F)(F)F)CC(C)O1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J09 compound treatment 741956.0 156000.0 0.7 717923.0 151000.0 0.75 1.0226 0.9993 1973051 ChemDiv1_005839 CC(C)Nc1nc(Cl)nc(Nc2cccc(c2)C(F)(F)F)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J10 compound treatment 703076.0 117000.0 0.52 716377.0 150000.0 0.74 0.8941 0.9852 1926396 ChemDiv1_005840 COC(=O)CN1C(=O)/C(=C/c2ccc(OCc3ccccc3Cl)c(OC)c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J11 compound treatment 738311.0 152000.0 0.68 732493.0 166000.0 0.82 1.0621 0.9956 1632333 ChemDiv1_005841 Cc1cccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J12 compound treatment 779210.0 193000.0 0.86 793207.0 227000.0 1.12 1.4042 0.9916 1944129 ChemDiv1_005842 On1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J13 compound treatment 717278.0 131000.0 0.59 693570.0 127000.0 0.63 0.8592 0.9994 1973052 ChemDiv1_005843 [O-][N+](=O)c1cccc(c1)C(C2C(=O)NC(=S)N(CC=C)C2=O)C3C(=O)NC(=S)N(CC=C)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J14 compound treatment 743277.0 157000.0 0.7 742916.0 176000.0 0.87 1.1143 0.9941 1784512 ChemDiv1_005844 CCOn1c(=O)c(C)[n+]([O-])c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J15 compound treatment 742813.0 156000.0 0.7 716234.0 150000.0 0.74 1.0194 0.9996 1344280 ChemDiv1_005845 Cc1ccc(Nc2nc3nonc3nc2NC(C)(C)C)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J16 compound treatment 749617.0 163000.0 0.73 737307.0 171000.0 0.85 1.1148 0.9973 1561938 ChemDiv1_005846 NC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J17 compound treatment 735212.0 149000.0 0.67 726568.0 160000.0 0.79 1.0316 0.9963 1973053 ChemDiv1_005847 Nc1nc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])c(C#N)c(c3ccco3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J18 compound treatment 725836.0 139000.0 0.62 694678.0 128000.0 0.63 0.8902 1.0 1973054 ChemDiv1_005848 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J19 compound treatment 738294.0 152000.0 0.68 723794.0 157000.0 0.78 1.0316 0.9977 1973055 ChemDiv1_005849 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)C(C)(C)C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J20 compound treatment 715321.0 129000.0 0.58 726722.0 160000.0 0.79 0.9691 0.9878 1235295 ChemDiv1_005850 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(Cl)cc3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J21 compound treatment 817040.0 231000.0 1.03 768975.0 202000.0 1.0 1.4391 0.9999 1973056 ChemDiv1_005851 CC/N=C/1\S/C(=C/c2ccc(o2)c3ccc(Cl)cc3C(=O)O)/C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J22 compound treatment 707769.0 121000.0 0.54 691988.0 125000.0 0.62 0.8236 0.9978 1143276 ChemDiv1_005852 Cc1ccc2NC(=O)C(O)(C3COC(C)(C)CC3=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J23 mock treatment 731349.0 145000.0 0.65 673045.0 107000.0 0.53 0.8318 0.9947 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 J24 mock treatment 516438.0 -70000.0 -0.31 509300.0 -57200.0 -0.28 -0.422 -0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K01 compound treatment 631453.0 45000.0 0.2 574199.0 7660.0 0.04 0.1694 0.8256 1973057 ChemDiv1_005853 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccc(F)cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K02 compound treatment 691808.0 105000.0 0.47 623327.0 56800.0 0.28 0.5325 0.9695 1973058 ChemDiv1_005854 O=C1C2CC=CCC2C(=O)N1c3ccc(cc3)c4nc5cc(ccc5[nH]4)N6C(=O)C7CC=CCC7C6=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K03 compound treatment 719251.0 133000.0 0.59 646188.0 79600.0 0.39 0.6995 0.9801 1973059 ChemDiv1_005855 COc1cccc(c1)c2nc3ccccc3c(=O)n2NC(=O)Cn4nc([N+](=O)[O-])c(Cl)c4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K04 compound treatment 731055.0 145000.0 0.65 662835.0 96300.0 0.48 0.7951 0.9887 1396082 ChemDiv1_005856 C(Nc1nc2nonc2nc1NCc3ccco3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K05 compound treatment 755316.0 169000.0 0.76 688034.0 121000.0 0.6 0.9602 0.9936 1223920 ChemDiv1_005857 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K06 compound treatment 728472.0 142000.0 0.64 658596.0 92100.0 0.46 0.7721 0.9867 1672960 ChemDiv1_005858 O=C1c2ccccc2-c3nn(c4ccccc4)c(=O)c5ccc(N6CCCCC6)c1c35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K07 compound treatment 783545.0 197000.0 0.88 673074.0 107000.0 0.53 0.9972 0.9698 1226654 ChemDiv1_005859 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(C)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K08 compound treatment 752870.0 166000.0 0.75 690714.0 124000.0 0.62 0.9619 0.9955 1928106 ChemDiv1_005860 Brc1ccc(cc1)C(=O)CSc2nnc[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K09 compound treatment 769128.0 183000.0 0.82 725607.0 159000.0 0.79 1.1355 0.9998 1973060 ChemDiv1_005861 CCOC(=O)C1=C(C)C2C3C(C(=O)N(C3=O)c4ccccc4F)C1(C)C5C2C(=O)N(C5=O)c6ccccc6F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K10 compound treatment 781268.0 195000.0 0.87 722206.0 156000.0 0.77 1.1621 0.9981 1583509 ChemDiv1_005862 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3ccc(OC(=O)N4CCOCC4)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K11 compound treatment 865976.0 280000.0 1.25 812575.0 246000.0 1.22 1.7467 0.9999 1973061 ChemDiv1_005863 COc1ccc(cc1)C2CC(=NN2c3ccccc3)c4c(C)cc(C)[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K12 compound treatment 761822.0 175000.0 0.79 684671.0 118000.0 0.59 0.969 0.9895 1320014 ChemDiv1_005864 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cc(Cl)cc(Cl)c3OC(=O)N4CCOCC4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K13 compound treatment 748013.0 162000.0 0.72 698915.0 132000.0 0.66 0.9752 0.9988 1473664 ChemDiv1_005865 CCN(c1ccccc1)c2nc3nonc3nc2NCCO 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K14 compound treatment 746065.0 160000.0 0.71 721958.0 155000.0 0.77 1.0498 0.9993 1742549 ChemDiv1_005866 CC(C)c1ccc(cc1)c2c(C#N)c(N)nc(SC3CCCCC3=O)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K15 compound treatment 779248.0 193000.0 0.86 744912.0 178000.0 0.88 1.2352 0.9999 1455489 ChemDiv1_005867 CC(Nc1nc2nonc2nc1N3CCCC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K16 compound treatment 763825.0 177000.0 0.79 702175.0 136000.0 0.67 1.0367 0.9965 1396915 ChemDiv1_005868 CCOc1ccccc1C2CC(=O)NC(=C2C#N)SCc3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K17 compound treatment 774717.0 188000.0 0.84 735391.0 169000.0 0.84 1.1875 1.0 1973062 ChemDiv1_005869 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K18 compound treatment 780401.0 194000.0 0.87 698672.0 132000.0 0.65 1.0769 0.9903 1973063 ChemDiv1_005870 COc1cc(ccc1OCc2ccccc2)C3CC(=O)NC(=C3C#N)SCC(=O)Nc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K19 compound treatment 766458.0 180000.0 0.81 731637.0 165000.0 0.82 1.1482 1.0 1973064 ChemDiv1_005871 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3cccc(OC)c3OC)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K20 compound treatment 750434.0 164000.0 0.73 707691.0 141000.0 0.7 1.0136 0.9997 1973065 ChemDiv1_005872 COc1cccc(c1)N2C(=O)/C(=C/c3ccc(OC)c(OC)c3OC)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K21 compound treatment 928702.0 342000.0 1.53 794291.0 228000.0 1.13 1.8812 0.9887 1420386 ChemDiv1_005873 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K22 compound treatment 756358.0 170000.0 0.76 681334.0 115000.0 0.57 0.94 0.9897 1597975 ChemDiv1_005874 O=C(CSc1nc2ccc(cc2s1)N3C(=O)C4C5CC(C=C5)C4C3=O)NC6CCCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K23 mock treatment 760526.0 174000.0 0.78 688471.0 122000.0 0.6 0.9782 0.9921 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 K24 mock treatment 383841.0 -203000.0 -0.91 511430.0 -55100.0 -0.27 -0.8342 -0.8809 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L01 compound treatment 632517.0 46100.0 0.21 588439.0 21900.0 0.11 0.2226 0.9549 1241989 ChemDiv1_005875 CCOc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)cc(Br)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L02 compound treatment 679831.0 93400.0 0.42 635705.0 69200.0 0.34 0.538 0.9951 1973066 ChemDiv1_005876 OCC(O)Cn1c(SCCOc2ccc(Cl)cc2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L03 compound treatment 723577.0 137000.0 0.61 663903.0 97400.0 0.48 0.7752 0.9929 1319586 ChemDiv1_005877 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(C)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L04 compound treatment 698991.0 113000.0 0.5 666729.0 100000.0 0.5 0.7073 1.0 1564150 ChemDiv1_005878 NC1=C(C#N)C2(C(=O)Nc3ccc(Cl)cc32)c4c(n[nH]c4O1)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L05 compound treatment 739318.0 153000.0 0.68 698809.0 132000.0 0.66 0.9473 0.9998 1404796 ChemDiv1_005879 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L06 compound treatment 707354.0 121000.0 0.54 686810.0 120000.0 0.6 0.8041 0.9989 1973067 ChemDiv1_005880 COc1cc(/C=C/2\SC(=S)N(CC(=O)Nc3ccccc3[N+](=O)[O-])C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L07 compound treatment 718877.0 132000.0 0.59 680344.0 114000.0 0.56 0.8179 0.9997 1197177 ChemDiv1_005881 Cc1ccc(Nc2nc3nonc3nc2NCCc4ccccc4)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L08 compound treatment 719058.0 133000.0 0.59 675637.0 109000.0 0.54 0.802 0.9989 1941587 ChemDiv1_005882 COc1ccccc1c2c(oc3c(CN4CC(C)OC(C)C4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L09 compound treatment 721132.0 135000.0 0.6 674448.0 108000.0 0.53 0.8044 0.9982 1973068 ChemDiv1_005883 FC(F)(F)c1cccc(Nc2nc(Cl)nc(NCc3ccco3)n2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L10 compound treatment 706691.0 120000.0 0.54 696413.0 130000.0 0.64 0.8356 0.9961 1973069 ChemDiv1_005884 Cc1ccc(Cc2cnc(NC(=O)/C(=C/c3ccc(OCC=C)cc3)/C#N)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L11 compound treatment 747816.0 161000.0 0.72 706267.0 140000.0 0.69 1.0003 0.9998 1604923 ChemDiv1_005885 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L12 compound treatment 718105.0 132000.0 0.59 690294.0 124000.0 0.61 0.8503 0.9998 1925984 ChemDiv1_005886 COn1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L13 compound treatment 703984.0 118000.0 0.53 669240.0 103000.0 0.51 0.7319 0.9999 1973070 ChemDiv1_005887 COc1cc(OC)c(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L14 compound treatment 724707.0 138000.0 0.62 719079.0 153000.0 0.76 0.9721 0.9951 1650900 ChemDiv1_005888 Clc1cccc(Nc2nc(nc3ccccc23)c4ccncc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L15 compound treatment 989113.0 403000.0 1.8 944706.0 378000.0 1.87 2.5993 0.9998 1416543 ChemDiv1_005889 CN(C)C(=O)Oc1cccc(c1)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L16 compound treatment 734830.0 148000.0 0.66 698495.0 132000.0 0.65 0.932 1.0 1469233 ChemDiv1_005890 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L17 compound treatment 849933.0 264000.0 1.18 804934.0 238000.0 1.18 1.6692 1.0 1230289 ChemDiv1_005891 CC(C)c1ccc(cc1)c2c(C#N)c(N)nc3sc(C(=O)Nc4nccs4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L18 compound treatment 730308.0 144000.0 0.64 695128.0 129000.0 0.64 0.9059 1.0 1434749 ChemDiv1_005892 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L19 compound treatment 729215.0 143000.0 0.64 718015.0 151000.0 0.75 0.9826 0.9968 1973071 ChemDiv1_005893 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4c(F)cccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L20 compound treatment 736153.0 150000.0 0.67 708913.0 142000.0 0.71 0.9727 0.9997 1395410 ChemDiv1_005894 Cc1cc(Br)ccc1NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L21 compound treatment 744211.0 158000.0 0.71 715799.0 149000.0 0.74 1.0223 0.9997 1973072 ChemDiv1_005895 COc1ccc(NC(=O)CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L22 compound treatment 706257.0 120000.0 0.54 673595.0 107000.0 0.53 0.7543 1.0 1636489 ChemDiv1_005896 CN1C(=O)C(O)(C2COC(C)(C)CC2=O)c3cc(C)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L23 mock treatment 730524.0 144000.0 0.65 694918.0 128000.0 0.64 0.9059 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 L24 mock treatment 506714.0 -79700.0 -0.36 514162.0 -52400.0 -0.26 -0.4357 -0.9878 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M01 compound treatment 642949.0 56500.0 0.25 581470.0 14900.0 0.07 0.2313 0.877 1973073 ChemDiv1_005897 Fc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M02 compound treatment 691165.0 105000.0 0.47 621128.0 54600.0 0.27 0.5228 0.9658 1973074 ChemDiv1_005898 Cc1ccc2[nH]c(SCC(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M03 compound treatment 730757.0 144000.0 0.65 670012.0 103000.0 0.51 0.8193 0.9934 1348261 ChemDiv1_005899 CCCCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M04 compound treatment 718196.0 132000.0 0.59 643971.0 77400.0 0.38 0.6884 0.9783 1973075 ChemDiv1_005900 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)c(OC)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M05 compound treatment 746890.0 160000.0 0.72 706045.0 140000.0 0.69 0.9966 0.9998 1134690 ChemDiv1_005901 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M06 compound treatment 738912.0 153000.0 0.68 676784.0 110000.0 0.55 0.8689 0.9939 1973076 ChemDiv1_005902 CCOC(=O)COc1c(Br)cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M07 compound treatment 777477.0 191000.0 0.86 709680.0 143000.0 0.71 1.1062 0.9957 1441546 ChemDiv1_005903 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(OC)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M08 compound treatment 744113.0 158000.0 0.71 672112.0 106000.0 0.52 0.869 0.9891 1638225 ChemDiv1_005904 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M09 compound treatment 1020747.0 434000.0 1.94 984039.0 417000.0 2.07 2.8372 0.9995 1973077 ChemDiv1_005905 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCC3CCCO3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M10 compound treatment 738317.0 152000.0 0.68 691585.0 125000.0 0.62 0.9188 0.9989 1973078 ChemDiv1_005906 CC(C)(C)c1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3OC(=O)N4CCOCC4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M11 compound treatment 794246.0 208000.0 0.93 750697.0 184000.0 0.91 1.3029 1.0 1973079 ChemDiv1_005907 COc1ccc(cc1)C2CC(=NN2c3ccccc3C)c4c(C)cc(C)[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M12 compound treatment 1060907.0 475000.0 2.12 914902.0 348000.0 1.73 2.7222 0.9947 1489443 ChemDiv1_005908 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3[nH]2)sc4CN(C)CCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M13 compound treatment 728466.0 142000.0 0.64 687422.0 121000.0 0.6 0.8731 0.9995 1973080 ChemDiv1_005909 CCCCOC(=O)c1ccc(NC(=O)CSc2nc3ccccc3n2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M14 compound treatment 816218.0 230000.0 1.03 781318.0 215000.0 1.06 1.4797 0.9999 1594030 ChemDiv1_005910 Cc1ccccc1NC(=O)c2c(C)nc(SCC(=O)c3ccc(O)c(O)c3)c(C#N)c2c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M15 compound treatment 744538.0 158000.0 0.71 709039.0 142000.0 0.71 0.9997 1.0 1973081 ChemDiv1_005911 COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(C)c3)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M16 compound treatment 740721.0 154000.0 0.69 694009.0 127000.0 0.63 0.9349 0.999 1202340 ChemDiv1_005912 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M17 compound treatment 783844.0 197000.0 0.88 707785.0 141000.0 0.7 1.1197 0.9933 1973082 ChemDiv1_005913 COc1ccc(CN2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M18 compound treatment 754618.0 168000.0 0.75 694193.0 128000.0 0.63 0.9796 0.9962 1654233 ChemDiv1_005914 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(OCc3ccccc3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M19 compound treatment 765850.0 179000.0 0.8 737983.0 171000.0 0.85 1.1685 0.9996 1973083 ChemDiv1_005915 COc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M20 compound treatment 761011.0 175000.0 0.78 693006.0 126000.0 0.63 0.9957 0.994 1973084 ChemDiv1_005916 COc1ccccc1N2C(=O)NC(=O)/C(=C\c3ccc(OC)c4ccccc34)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M21 compound treatment 813561.0 227000.0 1.02 741984.0 175000.0 0.87 1.3336 0.9969 1973085 ChemDiv1_005917 Fc1cccc(Cl)c1Cn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M22 compound treatment 746266.0 160000.0 0.72 680024.0 113000.0 0.56 0.9035 0.9929 1973086 ChemDiv1_005918 COC(=O)c1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5cccc([N+](=O)[O-])c5C4=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M23 mock treatment 753563.0 167000.0 0.75 678688.0 112000.0 0.56 0.9219 0.9893 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 M24 mock treatment 424847.0 -162000.0 -0.72 411971.0 -155000.0 -0.77 -1.0528 -0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N01 compound treatment 604449.0 18000.0 0.08 568488.0 1940.0 0.01 0.0639 0.7859 1402720 ChemDiv1_005919 CCOC(=O)c1c(NC(=O)c2ccc(OC)c(c2)S(=O)(=O)N3CCOCC3)sc4CCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N02 compound treatment 656937.0 70500.0 0.32 611313.0 44800.0 0.22 0.3801 0.9851 1973087 ChemDiv1_005920 NC(=O)Cn1c(SCCOc2ccc(Cl)cc2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N03 compound treatment 715995.0 130000.0 0.58 650782.0 84200.0 0.42 0.7053 0.9869 1148752 ChemDiv1_005921 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cc(C)ccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N04 compound treatment 680752.0 94300.0 0.42 632413.0 65900.0 0.33 0.5294 0.9919 1406793 ChemDiv1_005922 COc1cccc(NC(=O)CSc2nnc(SCC(=O)Nc3cccc(OC)c3)s2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N05 compound treatment 730735.0 144000.0 0.65 651811.0 85300.0 0.42 0.7555 0.9788 1434879 ChemDiv1_005923 CCN1C(=O)C2(C(=C(N)Oc3[nH]nc(c32)c4ccccc4)C#N)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N06 compound treatment 727204.0 141000.0 0.63 680791.0 114000.0 0.57 0.8459 0.9986 1973088 ChemDiv1_005924 CCc1nnc(NC(=O)CN2C(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N07 compound treatment 714775.0 128000.0 0.57 686351.0 120000.0 0.59 0.826 0.9999 1588058 ChemDiv1_005925 CC1(COC2(OC1)C(=O)N(CN3CCN(Cc4ccccc4)CC3)c5ccccc52)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N08 compound treatment 720347.0 134000.0 0.6 682167.0 116000.0 0.57 0.829 0.9997 1431459 ChemDiv1_005926 Clc1ccccc1Nc2ncnc3ccc(Br)cc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N09 compound treatment 749984.0 164000.0 0.73 690042.0 123000.0 0.61 0.9504 0.996 1539996 ChemDiv1_005927 CC1CCCN(CN2C(=O)C3(OCC(C)(CO3)c4ccccc4)c5ccccc25)C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N10 compound treatment 740765.0 154000.0 0.69 706375.0 140000.0 0.69 0.9784 1.0 1973089 ChemDiv1_005928 Cc1ccc(Cc2cnc(NC(=O)/C(=C\c3ccc(o3)c4ccc(F)cc4)/C#N)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N11 compound treatment 748565.0 162000.0 0.73 699711.0 133000.0 0.66 0.9797 0.9989 1973090 ChemDiv1_005929 Cc1ccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N12 compound treatment 710914.0 125000.0 0.56 668359.0 102000.0 0.5 0.7507 0.9988 1973091 ChemDiv1_005930 CCOC(=O)COn1c(=O)c(c2ccccc2)[n+]([O-])c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N13 compound treatment 736097.0 150000.0 0.67 706919.0 140000.0 0.7 0.9655 0.9998 1973092 ChemDiv1_005931 COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3C)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N14 compound treatment 716489.0 130000.0 0.58 682370.0 116000.0 0.57 0.8175 1.0 1267611 ChemDiv1_005932 Clc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N15 compound treatment 780187.0 194000.0 0.87 732538.0 166000.0 0.82 1.1948 0.9996 1429757 ChemDiv1_005933 NC1=C(C#N)C2(C(=O)Nc3ccc(Br)cc32)C4=C(CC(CC4=O)c5ccccc5)O1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N16 compound treatment 724892.0 138000.0 0.62 692683.0 126000.0 0.62 0.8802 1.0 1332457 ChemDiv1_005934 COc1ccc(cc1)n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N17 compound treatment 725132.0 139000.0 0.62 680397.0 114000.0 0.56 0.8379 0.9988 1973093 ChemDiv1_005935 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccc(s4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N18 compound treatment 725700.0 139000.0 0.62 703528.0 137000.0 0.68 0.9207 0.9991 1125562 ChemDiv1_005936 Cc1cccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N19 compound treatment 750089.0 164000.0 0.73 733066.0 167000.0 0.82 1.1014 0.9983 1717881 ChemDiv1_005937 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(OC)cc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N20 compound treatment 738295.0 152000.0 0.68 685448.0 119000.0 0.59 0.8973 0.9974 1228410 ChemDiv1_005938 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3cccc(F)c3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N21 compound treatment 735934.0 150000.0 0.67 674834.0 108000.0 0.54 0.8526 0.994 1973094 ChemDiv1_005939 COC(=O)C(C)Sc1nnc(o1)c2ccncc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N22 compound treatment 733496.0 147000.0 0.66 678655.0 112000.0 0.56 0.8583 0.9964 1947459 ChemDiv1_005940 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccc(F)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N23 mock treatment 718271.0 132000.0 0.59 666075.0 99500.0 0.49 0.766 0.996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 N24 mock treatment 529702.0 -56700.0 -0.25 409196.0 -157000.0 -0.78 -0.7307 -0.8913 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O01 compound treatment 641723.0 55300.0 0.25 583852.0 17300.0 0.09 0.2357 0.8996 1377390 ChemDiv1_005941 Cc1nc2ccccc2c(=O)n1OC(=O)c3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O02 compound treatment 633972.0 47600.0 0.21 583679.0 17100.0 0.08 0.2106 0.9187 1603342 ChemDiv1_005942 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)c4ccccc4)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O03 compound treatment 702405.0 116000.0 0.52 625915.0 59400.0 0.29 0.5751 0.9638 1153169 ChemDiv1_005943 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc3OCOc3c2)C(=O)Nc4ccccc4C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O04 compound treatment 662613.0 76200.0 0.34 586882.0 20300.0 0.1 0.3125 0.8784 1305348 ChemDiv1_005944 OC(=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)cc4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O05 compound treatment 743431.0 157000.0 0.7 668138.0 102000.0 0.5 0.8529 0.9866 1475998 ChemDiv1_005945 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(OC)c5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O06 compound treatment 689924.0 104000.0 0.46 645358.0 78800.0 0.39 0.6037 0.9964 1235464 ChemDiv1_005946 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(C#N)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O07 compound treatment 738978.0 153000.0 0.68 665203.0 98700.0 0.49 0.8285 0.9865 1262142 ChemDiv1_005947 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O08 compound treatment 758439.0 172000.0 0.77 645738.0 79200.0 0.39 0.8219 0.951 1354432 ChemDiv1_005948 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccccc5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O09 compound treatment 749798.0 163000.0 0.73 672520.0 106000.0 0.52 0.8884 0.9868 1973095 ChemDiv1_005949 Cc1ccc(N/C=C\2/C(=O)N(N=C2CSc3ccc(C)cc3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O10 compound treatment 725411.0 139000.0 0.62 626708.0 60200.0 0.3 0.6507 0.9432 1330581 ChemDiv1_005950 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc(OC(=O)N4CCOCC4)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O11 compound treatment 736564.0 150000.0 0.67 664351.0 97800.0 0.48 0.8179 0.9871 1515972 ChemDiv1_005951 Cc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)NCCc4c[nH]c5ccccc45)c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O12 compound treatment 702605.0 116000.0 0.52 646179.0 79600.0 0.39 0.6468 0.9907 1251221 ChemDiv1_005952 O=C(CSc1cccc2cccnc12)Nc3nc4c(ccc5ccccc45)s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O13 compound treatment 749031.0 163000.0 0.73 674278.0 108000.0 0.53 0.8921 0.9884 1973096 ChemDiv1_005953 CN(C)C(=O)C(Sc1nnc(c2ccc(Cl)cc2)n1c3ccccc3)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O14 compound treatment 740050.0 154000.0 0.69 647941.0 81400.0 0.4 0.7714 0.9676 1410142 ChemDiv1_005954 COc1ccc(cc1)c2c(C#N)c(N)nc(SC3CCCCC3=O)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O15 compound treatment 807650.0 221000.0 0.99 731421.0 165000.0 0.82 1.2778 0.9954 1973097 ChemDiv1_005955 CCN(CC)c1ccc(/C=C/2\C(=O)NC(=O)N(Cc3ccc(OC)cc3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O16 compound treatment 664625.0 78200.0 0.35 642646.0 76100.0 0.38 0.5142 0.9993 1388075 ChemDiv1_005956 COC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O17 compound treatment 760856.0 174000.0 0.78 692588.0 126000.0 0.62 0.9937 0.9939 1973098 ChemDiv1_005957 COc1cc(/C=C/2\C(=O)NC(=O)N(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O18 compound treatment 740839.0 154000.0 0.69 670147.0 104000.0 0.51 0.8517 0.9892 1609194 ChemDiv1_005958 COC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(OC)c(OCc3ccccc3)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O19 compound treatment 761997.0 176000.0 0.79 681531.0 115000.0 0.57 0.9586 0.9875 1782052 ChemDiv1_005959 CCOC(=O)c1c(NC(=O)Cn2nc(C)c([N+](=O)[O-])c2C)sc3CC(CCc13)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O20 compound treatment 724386.0 138000.0 0.62 692057.0 126000.0 0.62 0.8764 1.0 1973099 ChemDiv1_005960 COc1ccccc1N2C(=O)NC(=O)/C(=C\c3cc(OC)c(O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O21 compound treatment 728659.0 142000.0 0.64 674763.0 108000.0 0.54 0.8293 0.9963 1913327 ChemDiv1_005961 FC(F)(F)C(=O)Nc1nnc([nH]1)c2nnc(NC(=O)C(F)(F)F)[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O22 compound treatment 709487.0 123000.0 0.55 643267.0 76700.0 0.38 0.6583 0.9836 1530759 ChemDiv1_005962 O=C(CN1C(=O)c2ccccc2S1(=O)=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O23 mock treatment 725383.0 139000.0 0.62 657290.0 90700.0 0.45 0.7578 0.9873 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 O24 mock treatment 447366.0 -139000.0 -0.62 223615.0 -343000.0 -1.7 -1.6413 -0.9072 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P01 compound treatment 598235.0 11800.0 0.05 544429.0 -22100.0 -0.11 -0.04 -0.3289 1973100 ChemDiv1_005963 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc(cc3)[N+](=O)[O-])c4c(F)cccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P02 compound treatment 628721.0 42300.0 0.19 553531.0 -13000.0 -0.06 0.0884 0.4416 1650438 ChemDiv1_005964 CCCOc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P03 compound treatment 631883.0 45500.0 0.2 574306.0 7760.0 0.04 0.1711 0.8261 1784757 ChemDiv1_005965 Cc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)[N+](=O)[O-])c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P04 compound treatment 640538.0 54100.0 0.24 579013.0 12500.0 0.06 0.215 0.8599 1306347 ChemDiv1_005966 O=C(CC1SC(=O)NC1=O)Nc2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P05 compound treatment 609979.0 23600.0 0.11 572914.0 6370.0 0.03 0.0969 0.8801 1973101 ChemDiv1_005967 CCOc1cc(ccc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P06 compound treatment 663903.0 77500.0 0.35 606162.0 39600.0 0.2 0.3841 0.9636 1950296 ChemDiv1_005968 Oc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P07 compound treatment 673036.0 86600.0 0.39 609186.0 42600.0 0.21 0.4236 0.9592 1283958 ChemDiv1_005969 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4cccc(OC(=O)N5CCOCC5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P08 compound treatment 665111.0 78700.0 0.35 608874.0 42300.0 0.21 0.3974 0.9693 1941168 ChemDiv1_005970 CC(=O)c1cccc(Nc2ncnc3ccc(Br)cc23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P09 compound treatment 666297.0 79900.0 0.36 605405.0 38900.0 0.19 0.389 0.9578 1973102 ChemDiv1_005971 Brc1ccc(CN2CCN(CCNC(=O)C(=O)Nc3ccccc3)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P10 compound treatment 701384.0 115000.0 0.51 626175.0 59600.0 0.3 0.5728 0.9653 1973103 ChemDiv1_005972 Cc1ccc(Cc2cnc(NC(=O)/C(=C\c3ccc(o3)c4ccc(cc4)[N+](=O)[O-])/C#N)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P11 compound treatment 681796.0 95400.0 0.43 600548.0 34000.0 0.17 0.421 0.9173 1456147 ChemDiv1_005973 NS(=O)(=O)c1ccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P12 compound treatment 695419.0 109000.0 0.49 612963.0 46400.0 0.23 0.5077 0.9411 1973104 ChemDiv1_005974 Cc1[n+]([O-])c2ccccc2n(OCc3ccccc3)c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P13 compound treatment 692887.0 106000.0 0.48 604878.0 38300.0 0.19 0.4713 0.9186 1973105 ChemDiv1_005975 COc1ccc2ccccc2c1/C=C/3\C(=O)NC(=O)N(C3=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P14 compound treatment 702441.0 116000.0 0.52 622225.0 55700.0 0.28 0.5623 0.9562 1172751 ChemDiv1_005976 Brc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P15 compound treatment 679094.0 92700.0 0.41 605504.0 39000.0 0.19 0.4299 0.9394 1973106 ChemDiv1_005977 COc1ccc(cc1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc(OC(=O)N5CCOCC5)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P16 compound treatment 707546.0 121000.0 0.54 624934.0 58400.0 0.29 0.588 0.9567 1649547 ChemDiv1_005978 Cc1cccc(c1)n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P17 compound treatment 699290.0 113000.0 0.51 610238.0 43700.0 0.22 0.5104 0.9284 1606823 ChemDiv1_005979 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccc(OC(=O)c5ccco5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P18 compound treatment 690270.0 104000.0 0.46 601776.0 35200.0 0.17 0.4522 0.9105 1414985 ChemDiv1_005980 Cc1c(Cl)cccc1NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P19 compound treatment 706272.0 120000.0 0.54 619159.0 52600.0 0.26 0.5637 0.945 1973107 ChemDiv1_005981 Clc1ccccc1CN2CCN(CCNC(=O)C(=O)Nc3ccc(Br)cc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P20 compound treatment 665515.0 79100.0 0.35 604207.0 37700.0 0.19 0.3823 0.9552 1783036 ChemDiv1_005982 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(F)c(c3)[N+](=O)[O-])c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P21 compound treatment 686649.0 100000.0 0.45 615725.0 49200.0 0.24 0.4896 0.9588 1633451 ChemDiv1_005983 Clc1nc(NCc2ccco2)nc(n1)N3CCC(Cc4ccccc4)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P22 compound treatment 642381.0 56000.0 0.25 580428.0 13900.0 0.07 0.2258 0.8691 1947799 ChemDiv1_005984 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P23 mock treatment 659655.0 73200.0 0.33 603606.0 37100.0 0.18 0.3617 0.9624 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.603 P24 mock treatment 176295.0 -410000.0 -1.84 309658.0 -257000.0 -1.27 -2.198 -0.984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A01 compound treatment 594351.0 -18500.0 -0.08 540986.0 -14100.0 -0.07 -0.1081 -0.9964 1947446 ChemDiv1_005985 COc1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)/C(=N\c4ccccc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A02 compound treatment 586732.0 -26100.0 -0.12 544076.0 -11000.0 -0.05 -0.1214 -0.9398 1481169 ChemDiv1_005986 CCOC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A03 compound treatment 594978.0 -17900.0 -0.08 553944.0 -1150.0 -0.01 -0.0607 -0.7556 1488783 ChemDiv1_005987 Clc1cccc(NC(=O)Nc2nc(cs2)c3ccccc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A04 compound treatment 578913.0 -34000.0 -0.15 557317.0 2220.0 0.01 -0.0997 -0.6543 1278626 ChemDiv1_005988 COC(=O)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC(=C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A05 compound treatment 625367.0 12500.0 0.06 573994.0 18900.0 0.09 0.1057 0.9697 1253323 ChemDiv1_005989 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A06 compound treatment 620768.0 7890.0 0.04 608015.0 52900.0 0.26 0.2103 0.7952 1973108 ChemDiv1_005990 CCOC(=O)c1c(C)n(CC(COC(=O)C)OC(=O)C)c2ccc(OC(=O)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A07 compound treatment 626346.0 13500.0 0.06 600017.0 44900.0 0.22 0.2 0.8674 1973109 ChemDiv1_005991 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(ccc3Cl)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A08 compound treatment 643455.0 30600.0 0.14 621512.0 66400.0 0.33 0.3294 0.9245 1947556 ChemDiv1_005992 CC(=O)OCc1c(OC(=O)C)ccc2c([N+](=O)[O-])c(C)n(c3ccc(C)cc3)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A09 compound treatment 626480.0 13600.0 0.06 601322.0 46200.0 0.23 0.205 0.8651 1973110 ChemDiv1_005993 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3cccc(c3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A10 compound treatment 658736.0 45900.0 0.21 627943.0 72800.0 0.36 0.4003 0.9643 1973111 ChemDiv1_005994 COc1ccc(cc1)c2cc(c(C#N)c(N)n2)c3cccc(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A11 compound treatment 588809.0 -24100.0 -0.11 626301.0 71200.0 0.35 0.1732 0.4697 1519849 ChemDiv1_005995 Cc1ccn2cc(nc2c1)c3cccc(NC(=O)c4cc5cc(Br)ccc5oc4=O)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A12 compound treatment 633314.0 20400.0 0.09 615489.0 60400.0 0.3 0.2762 0.883 1973112 ChemDiv1_005996 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc6OCOc6cc5[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A13 compound treatment 620254.0 7380.0 0.03 623935.0 68800.0 0.34 0.2645 0.772 1681646 ChemDiv1_005997 COc1ccc(Cl)cc1C(=O)On2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A14 compound treatment 633077.0 20200.0 0.09 605672.0 50600.0 0.25 0.2411 0.9052 1412711 ChemDiv1_005998 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(F)c(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A15 compound treatment 637234.0 24400.0 0.11 651116.0 96000.0 0.48 0.4134 0.8472 1973113 ChemDiv1_005999 CCOC(=O)CSc1nc2sc3CC(CCc3c2c(=O)[nH]1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A16 compound treatment 633082.0 20200.0 0.09 627217.0 72100.0 0.36 0.3166 0.859 1185413 ChemDiv1_006000 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)Nc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A17 compound treatment 835109.0 222000.0 0.99 803754.0 249000.0 1.23 1.5744 0.9944 1786017 ChemDiv1_006001 CCn1c(=O)c2c3CCN(C)Cc3sc2[nH]c1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A18 compound treatment 626524.0 13600.0 0.06 620808.0 65700.0 0.33 0.2734 0.8254 1532603 ChemDiv1_006002 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A19 compound treatment 635124.0 22200.0 0.1 611883.0 56800.0 0.28 0.2693 0.9026 1973114 ChemDiv1_006003 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A20 compound treatment 620006.0 7130.0 0.03 586515.0 31400.0 0.16 0.1326 0.8348 1718388 ChemDiv1_006004 COc1cc(ccc1OC(=O)C)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A21 compound treatment 625164.0 12300.0 0.06 578770.0 23700.0 0.12 0.1218 0.9405 1933565 ChemDiv1_006005 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A22 compound treatment 595040.0 -17800.0 -0.08 560480.0 5380.0 0.03 -0.0376 -0.4467 1973115 ChemDiv1_006006 C(C1CCN(CC1)c2nc3nonc3nc2Nc4ccc5OCOc5c4)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A23 mock treatment 590037.0 -22800.0 -0.1 554027.0 -1070.0 -0.01 -0.076 -0.7428 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 A24 mock treatment 508054.0 -105000.0 -0.47 476595.0 -78500.0 -0.39 -0.6068 -0.9956 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B01 compound treatment 622719.0 9840.0 0.04 579929.0 24800.0 0.12 0.1181 0.9041 1973116 ChemDiv1_006007 Oc1c(CN2CCN(CC2)c3cccc(c3)C(F)(F)F)cc([N+](=O)[O-])c4cccnc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B02 compound treatment 666397.0 53500.0 0.24 606524.0 51400.0 0.25 0.3496 0.9995 1973117 ChemDiv1_006008 COC(=O)CC1SC(=O)NC1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B03 compound treatment 708664.0 95800.0 0.43 688884.0 134000.0 0.66 0.7718 0.9778 1973118 ChemDiv1_006009 CCCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)/c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B04 compound treatment 681315.0 68400.0 0.31 670915.0 116000.0 0.57 0.6223 0.9568 1623729 ChemDiv1_006010 O=C(Nc1cccc2nsnc12)c3ccc4OCCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B05 compound treatment 724387.0 112000.0 0.5 715310.0 160000.0 0.79 0.9142 0.975 1973119 ChemDiv1_006011 CCCn1c(NC(=O)C)nc2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B06 compound treatment 700015.0 87100.0 0.39 661672.0 107000.0 0.53 0.6491 0.9889 1973120 ChemDiv1_006012 O=C1c2ccccc2C(=O)c3c(cccc13)c4ccc(C=c5sc6nc7ccccc7n6c5=O)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B07 compound treatment 737859.0 125000.0 0.56 756115.0 201000.0 1.0 1.0997 0.9628 1973121 ChemDiv1_006013 CCCC/1=NN(C(=O)\C1=C(/C)\NCCO)c2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B08 compound treatment 748199.0 135000.0 0.61 730319.0 175000.0 0.87 1.0421 0.9845 1358997 ChemDiv1_006014 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NC(=O)c4cc(Cl)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B09 compound treatment 753105.0 140000.0 0.63 752911.0 198000.0 0.98 1.1368 0.9768 1973122 ChemDiv1_006015 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccc(Cl)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B10 compound treatment 774730.0 162000.0 0.72 743060.0 188000.0 0.93 1.1707 0.9923 1973123 ChemDiv1_006016 FC(F)(F)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B11 compound treatment 861753.0 249000.0 1.11 886099.0 331000.0 1.64 1.9472 0.9823 1973124 ChemDiv1_006017 CC1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(Cc5ccccc5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B12 compound treatment 682723.0 69800.0 0.31 724772.0 170000.0 0.84 0.8154 0.9093 1188772 ChemDiv1_006018 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B13 compound treatment 830437.0 218000.0 0.97 895158.0 340000.0 1.68 1.8798 0.9661 1973125 ChemDiv1_006019 CN1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(Cc5ccccc5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B14 compound treatment 714526.0 102000.0 0.46 729872.0 175000.0 0.87 0.934 0.9549 1394214 ChemDiv1_006020 COc1ccc(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B15 compound treatment 761269.0 148000.0 0.66 754872.0 200000.0 0.99 1.1695 0.9812 1395003 ChemDiv1_006021 CCCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B16 compound treatment 2.187285E7 2.13E7 95.17 2.1574496E7 2.1E7 104.13 140.9219 0.999 1445404 ChemDiv1_006022 CC1CCCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B17 compound treatment 746301.0 133000.0 0.6 765662.0 211000.0 1.04 1.1599 0.965 1298832 ChemDiv1_006023 COc1ccc(cc1)c2nnc(Nc3c(C)n(C)n(c4ccccc4)c3=O)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B18 compound treatment 725345.0 112000.0 0.5 738130.0 183000.0 0.91 0.9971 0.9615 1924804 ChemDiv1_006024 COCCOC(=O)c1c(C)oc2ccc(OCc3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B19 compound treatment 746047.0 133000.0 0.6 742710.0 188000.0 0.93 1.0787 0.977 1216509 ChemDiv1_006025 CCOC(=O)Cc1nnc(Nc2ccc(OC)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B20 compound treatment 695699.0 82800.0 0.37 697303.0 142000.0 0.7 0.7603 0.9551 1584103 ChemDiv1_006026 COC(=O)c1c(C)oc2ccc(OC(=O)c3c(C)oc4ccc(OC(=O)C)cc34)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B21 compound treatment 732498.0 120000.0 0.54 719862.0 165000.0 0.82 0.9558 0.9791 1357985 ChemDiv1_006027 OCCNC(=O)c1ccc(cc1)c2nnc(N3CCOCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B22 compound treatment 675141.0 62300.0 0.28 668211.0 113000.0 0.56 0.5933 0.948 1405592 ChemDiv1_006028 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B23 mock treatment 690452.0 77600.0 0.35 651797.0 96700.0 0.48 0.5843 0.9875 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 B24 mock treatment 535568.0 -77300.0 -0.35 488980.0 -66100.0 -0.33 -0.4763 -0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C01 compound treatment 621476.0 8600.0 0.04 538804.0 -16300.0 -0.08 -0.0299 -0.3338 1785884 ChemDiv1_006029 CCOc1cc(ccc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C02 compound treatment 651146.0 38300.0 0.17 603161.0 48100.0 0.24 0.2895 0.987 1973126 ChemDiv1_006030 CCn1c(SCc2ccccc2)nc3sc4COC(C)(C)Cc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C03 compound treatment 693350.0 80500.0 0.36 643627.0 88500.0 0.44 0.5648 0.9952 1370836 ChemDiv1_006031 O=C(NC1CCCCC1)Nc2nc(cs2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C04 compound treatment 672478.0 59600.0 0.27 659488.0 104000.0 0.52 0.5543 0.9526 1973127 ChemDiv1_006032 COC(=O)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C05 compound treatment 715501.0 103000.0 0.46 652436.0 97300.0 0.48 0.6658 0.9997 1577212 ChemDiv1_006033 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C06 compound treatment 694598.0 81700.0 0.37 667407.0 112000.0 0.56 0.6521 0.9793 1973128 ChemDiv1_006034 CCOC(=O)c1c(C)n(c2ccc(Cl)cc2)c3ccc(Oc4nccc(Nc5ccccc5)c4C#N)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C07 compound treatment 664360.0 51500.0 0.23 688742.0 134000.0 0.66 0.6311 0.9003 1927676 ChemDiv1_006035 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C08 compound treatment 689766.0 76900.0 0.34 684967.0 130000.0 0.64 0.6983 0.9571 1916527 ChemDiv1_006036 CN(C)Cc1c(O)ccc2c([N+](=O)[O-])c(/C=C/N(C)C)n(c3ccc(C)cc3)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C09 compound treatment 738204.0 125000.0 0.56 702313.0 147000.0 0.73 0.9124 0.9916 1634848 ChemDiv1_006037 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C10 compound treatment 683545.0 70700.0 0.32 665790.0 111000.0 0.55 0.6114 0.9658 1730163 ChemDiv1_006038 CC(C)Cc1cc(c(C#N)c(O)n1)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C11 compound treatment 741238.0 128000.0 0.57 726186.0 171000.0 0.85 1.0056 0.9821 1254019 ChemDiv1_006039 Cc1nc(sc1C(=O)Nc2cccc(c2)c3cn4ccccc4n3)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C12 compound treatment 698379.0 85500.0 0.38 720717.0 166000.0 0.82 0.8508 0.9397 1311863 ChemDiv1_006040 COc1cc(cc(Br)c1OC)C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C13 compound treatment 726109.0 113000.0 0.51 716399.0 161000.0 0.8 0.9234 0.9759 1973129 ChemDiv1_006041 Cc1c(Br)c(nn1CC(=O)Nn2c(nc3ccccc3c2=O)c4ccccc4F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C14 compound treatment 739647.0 127000.0 0.57 705492.0 150000.0 0.75 0.9281 0.991 1483240 ChemDiv1_006042 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccccc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C15 compound treatment 754790.0 142000.0 0.64 733211.0 178000.0 0.88 1.0731 0.987 1669237 ChemDiv1_006043 Cc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C16 compound treatment 729287.0 116000.0 0.52 711937.0 157000.0 0.78 0.9179 0.9811 1973130 ChemDiv1_006044 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C17 compound treatment 745714.0 133000.0 0.59 705539.0 150000.0 0.75 0.9474 0.9937 1688044 ChemDiv1_006045 COc1ccc(cc1)n2c(=O)c3c4CCC(Cc4sc3[nH]c2=S)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C18 compound treatment 691412.0 78500.0 0.35 696443.0 141000.0 0.7 0.7437 0.9492 1309826 ChemDiv1_006046 CCOc1cc(ccc1OC(=O)C2CC2)C3Nc4cc(C)c(C)cc4NC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C19 compound treatment 719363.0 106000.0 0.48 690680.0 136000.0 0.67 0.812 0.9859 1973131 ChemDiv1_006047 COC(=O)CSc1nnc2n(c3ccccc3)c(=O)c4c5CC(C)(C)OCc5sc4n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C20 compound treatment 698677.0 85800.0 0.38 665983.0 111000.0 0.55 0.66 0.9847 1528142 ChemDiv1_006048 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(OC)cc2)C(=O)Nc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C21 compound treatment 731565.0 119000.0 0.53 688683.0 134000.0 0.66 0.8436 0.9941 1946371 ChemDiv1_006049 COC(=O)CSc1nnc2n(c3ccc(OC)cc3)c(=O)c4c5CC(C)(C)OCc5sc4n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C22 compound treatment 664781.0 51900.0 0.23 651388.0 96300.0 0.48 0.5016 0.9454 1433318 ChemDiv1_006050 C(Nc1nc2nonc2nc1NCc3ccc4OCOc4c3)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C23 mock treatment 707349.0 94500.0 0.42 641761.0 86700.0 0.43 0.6026 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 C24 mock treatment 539847.0 -73000.0 -0.33 204341.0 -351000.0 -1.74 -1.4598 -0.8257 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D01 compound treatment 611281.0 -1590.0 -0.01 574617.0 19500.0 0.1 0.0633 0.6531 1973132 ChemDiv1_006051 Oc1c(cc(CN2CCN(CC2)c3cccc(c3)C(F)(F)F)c4cccnc14)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D02 compound treatment 656012.0 43100.0 0.19 627608.0 72500.0 0.36 0.3905 0.9576 1281108 ChemDiv1_006052 CCOC(=O)c1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D03 compound treatment 713063.0 100000.0 0.45 669835.0 115000.0 0.57 0.719 0.9931 1973133 ChemDiv1_006053 C/C(=C\1/C(=O)N(N=C1CSc2ccc(C)cc2)c3nc4ccccc4s3)/NCCN5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D04 compound treatment 702712.0 89800.0 0.4 664035.0 109000.0 0.54 0.666 0.9895 1214369 ChemDiv1_006054 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2C)c3nc4cc(Cl)cc(Cl)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D05 compound treatment 723947.0 111000.0 0.5 692469.0 137000.0 0.68 0.8328 0.9881 1149271 ChemDiv1_006055 CCC(=O)Nc1nc2ccccc2n1Cc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D06 compound treatment 698849.0 86000.0 0.38 680028.0 125000.0 0.62 0.7097 0.9739 1973134 ChemDiv1_006056 Cc1ccc(cc1)S(=O)(=O)n2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D07 compound treatment 742311.0 129000.0 0.58 734550.0 179000.0 0.89 1.0383 0.9785 1973135 ChemDiv1_006057 CC/1=NN(C(=O)\C1=C\NCCN2CCN(CC2)C(=S)NCC=C)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D08 compound treatment 742356.0 129000.0 0.58 739705.0 185000.0 0.91 1.0565 0.9758 1973136 ChemDiv1_006058 COc1cc(/C=C/C(=O)Nn2c(nc3ccccc3c2=O)c4cccs4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D09 compound treatment 762732.0 150000.0 0.67 774047.0 219000.0 1.08 1.2413 0.9733 1973137 ChemDiv1_006059 COc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccc(Cl)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D10 compound treatment 732410.0 120000.0 0.54 736575.0 181000.0 0.9 1.0141 0.9693 1973138 ChemDiv1_006060 Cc1cc(Br)ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D11 compound treatment 2133028.0 1520000.0 6.8 1969043.0 1410000.0 7.0 9.7646 0.9999 1973139 ChemDiv1_006061 OCCN1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C/4\SC(=S)N(C5CCCCC5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D12 compound treatment 685868.0 73000.0 0.33 746324.0 191000.0 0.95 0.9009 0.899 1520227 ChemDiv1_006062 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D13 compound treatment 1044042.0 431000.0 1.93 1086277.0 531000.0 2.63 3.2254 0.9884 1973140 ChemDiv1_006063 CC(N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(C)CC4)/SC1=S)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D14 compound treatment 746226.0 133000.0 0.6 748919.0 194000.0 0.96 1.101 0.9739 1973141 ChemDiv1_006064 COc1ccccc1/C=C/CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D15 compound treatment 770344.0 157000.0 0.7 761949.0 207000.0 1.02 1.223 0.9833 1973142 ChemDiv1_006065 CCCCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D16 compound treatment 8962484.0 8350000.0 37.38 1.0068868E7 9510000.0 47.13 59.7543 0.9934 1331060 ChemDiv1_006066 CC1CCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D17 compound treatment 740356.0 127000.0 0.57 783672.0 229000.0 1.13 1.2042 0.9497 1549604 ChemDiv1_006067 CC(=O)Nc1ccc(Oc2nnc(c3ccc(C)cc3)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D18 compound treatment 732198.0 119000.0 0.53 723165.0 168000.0 0.83 0.9664 0.977 1973143 ChemDiv1_006068 COC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D19 compound treatment 746503.0 134000.0 0.6 765218.0 210000.0 1.04 1.159 0.9654 1553917 ChemDiv1_006069 COC(=O)Cc1nnc(Nc2cccc(C)c2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D20 compound treatment 725661.0 113000.0 0.5 751263.0 196000.0 0.97 1.0441 0.9535 1929637 ChemDiv1_006070 Cc1csc(n1)c2cc3ccc(OCc4c(F)c(F)c(F)c(F)c4F)cc3oc2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D21 compound treatment 736435.0 124000.0 0.55 740640.0 186000.0 0.92 1.041 0.9705 1282096 ChemDiv1_006071 OCCNC(=O)c1ccc(cc1)c2nnc(Nc3ccc(O)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D22 compound treatment 710511.0 97600.0 0.44 714272.0 159000.0 0.79 0.8666 0.9613 1246059 ChemDiv1_006072 COc1ccc(cc1)C(=O)COc2cc3c(C(=O)OC(C)C)c(C)oc3cc2Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D23 mock treatment 719116.0 106000.0 0.48 662262.0 107000.0 0.53 0.7117 0.9985 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 D24 mock treatment 521502.0 -91400.0 -0.41 499909.0 -55200.0 -0.27 -0.4825 -0.9808 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E01 compound treatment 646864.0 34000.0 0.15 563403.0 8310.0 0.04 0.1367 0.8672 1543733 ChemDiv1_006073 CCC(C)C(=O)N1C(C)CC(N(C(=O)COc2ccccc2)c3ccccc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E02 compound treatment 674641.0 61800.0 0.28 600413.0 45300.0 0.22 0.3542 0.9947 1177834 ChemDiv1_006074 COc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E03 compound treatment 718009.0 105000.0 0.47 654513.0 99400.0 0.49 0.681 0.9997 1538593 ChemDiv1_006075 COc1ccc(cc1OC)C(NC(=O)Cc2ccccc2)c3ccc4cccnc4c3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E04 compound treatment 758916.0 146000.0 0.65 706510.0 151000.0 0.75 0.9926 0.9977 1210289 ChemDiv1_006076 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E05 compound treatment 733551.0 121000.0 0.54 701089.0 146000.0 0.72 0.8934 0.9897 1119689 ChemDiv1_006077 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E06 compound treatment 724707.0 112000.0 0.5 683202.0 128000.0 0.63 0.8027 0.9931 1217122 ChemDiv1_006078 CCOC(=O)c1c(CN(C)C)n(c2ccccc2)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E07 compound treatment 743351.0 130000.0 0.58 713105.0 158000.0 0.78 0.9665 0.9896 1973144 ChemDiv1_006079 COCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E08 compound treatment 781748.0 169000.0 0.76 709362.0 154000.0 0.76 1.0749 1.0 1586029 ChemDiv1_006080 COc1cc(ccc1O)C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E09 compound treatment 774550.0 162000.0 0.72 724310.0 169000.0 0.84 1.1045 0.9973 1141435 ChemDiv1_006081 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E10 compound treatment 758743.0 146000.0 0.65 721979.0 167000.0 0.83 1.0463 0.9932 1344690 ChemDiv1_006082 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E11 compound treatment 790653.0 178000.0 0.8 729640.0 175000.0 0.86 1.1741 0.9991 1337531 ChemDiv1_006083 Cc1nc(sc1C(=O)Nc2cccc(c2)c3cn4ccc(C)cc4n3)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E12 compound treatment 695785.0 82900.0 0.37 702774.0 148000.0 0.73 0.7797 0.9505 1973145 ChemDiv1_006084 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E13 compound treatment 740214.0 127000.0 0.57 686566.0 131000.0 0.65 0.8636 0.9978 1973146 ChemDiv1_006085 Cc1nc2ccccc2c(=O)n1OC(=O)/C=C/c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E14 compound treatment 785548.0 173000.0 0.77 762768.0 208000.0 1.03 1.274 0.9901 1428416 ChemDiv1_006086 COc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E15 compound treatment 783488.0 171000.0 0.76 757261.0 202000.0 1.0 1.2482 0.9911 1973147 ChemDiv1_006087 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E16 compound treatment 764975.0 152000.0 0.68 722997.0 168000.0 0.83 1.0696 0.9951 1461344 ChemDiv1_006088 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E17 compound treatment 785644.0 173000.0 0.77 750066.0 195000.0 0.97 1.2298 0.9939 1230233 ChemDiv1_006089 CC(C)(C)C1CCc2c(C1)sc3[nH]c(=S)[nH]c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E18 compound treatment 734529.0 122000.0 0.54 699402.0 144000.0 0.71 0.8905 0.991 1250418 ChemDiv1_006090 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E19 compound treatment 775983.0 163000.0 0.73 697445.0 142000.0 0.71 1.0149 0.9998 1973148 ChemDiv1_006091 CC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(Cc4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E20 compound treatment 719615.0 107000.0 0.48 719208.0 164000.0 0.81 0.9127 0.9679 1950556 ChemDiv1_006092 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(C)c(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E21 compound treatment 747799.0 135000.0 0.6 728675.0 174000.0 0.86 1.0351 0.9851 1414682 ChemDiv1_006093 CC(C)Cn1c(=O)c2c3CC(C)(C)OCc3sc2[nH]c1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E22 compound treatment 731504.0 119000.0 0.53 698192.0 143000.0 0.71 0.8767 0.9899 1266337 ChemDiv1_006094 CC1CCCN(C1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E23 mock treatment 751890.0 139000.0 0.62 658376.0 103000.0 0.51 0.8018 0.9953 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 E24 mock treatment 509363.0 -104000.0 -0.46 343913.0 -211000.0 -1.05 -1.0674 -0.9329 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F01 compound treatment 640291.0 27400.0 0.12 604480.0 49400.0 0.24 0.2598 0.9491 1973149 ChemDiv1_006095 COc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3Br)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F02 compound treatment 686185.0 73300.0 0.33 653479.0 98400.0 0.49 0.5767 0.9815 1973150 ChemDiv1_006096 COc1ccc(Cl)cc1N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F03 compound treatment 708675.0 95800.0 0.43 690947.0 136000.0 0.67 0.7791 0.9763 1973151 ChemDiv1_006097 C/C(=C\1/C(=O)N(N=C1CSc2ccc(C)cc2)c3nc4ccccc4s3)/NCc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F04 compound treatment 691417.0 78500.0 0.35 697233.0 142000.0 0.7 0.7465 0.9485 1229590 ChemDiv1_006098 Cc1ccc(cc1NC(=O)c2ccc3OCCOc3c2)c4nc5cc(Cl)cc(Cl)c5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F05 compound treatment 741729.0 129000.0 0.58 717240.0 162000.0 0.8 0.9758 0.9868 1925029 ChemDiv1_006099 COc1cccc(c1)C(=O)N2C(C)CC(N(C(=O)C(F)(F)F)c3ccccc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F06 compound treatment 729756.0 117000.0 0.52 721936.0 167000.0 0.83 0.9544 0.9757 1450429 ChemDiv1_006100 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F07 compound treatment 756198.0 143000.0 0.64 724789.0 170000.0 0.84 1.0481 0.9911 1234384 ChemDiv1_006101 Cc1ccc(cc1)C2N(C(=O)CCC(=O)O)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F08 compound treatment 732748.0 120000.0 0.54 724338.0 169000.0 0.84 0.9723 0.9767 1168164 ChemDiv1_006102 Cc1nc2sc3CCCCc3c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F09 compound treatment 760501.0 148000.0 0.66 754489.0 199000.0 0.99 1.1657 0.9809 1973152 ChemDiv1_006103 CC/1=NN(C(=O)\C1=C\NCc2ccc3OCOc3c2)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F10 compound treatment 732354.0 119000.0 0.53 741768.0 187000.0 0.92 1.0321 0.9661 1973153 ChemDiv1_006104 Clc1ccc(Oc2ccc(NC(=O)Cn3c4ccccc4c(=O)c5ccccc35)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F11 compound treatment 2562912.0 1950000.0 8.73 2326690.0 1770000.0 8.78 12.3781 1.0 1973154 ChemDiv1_006105 CC(C)CN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F12 compound treatment 751761.0 139000.0 0.62 729215.0 174000.0 0.86 1.0495 0.9871 1532399 ChemDiv1_006106 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F13 compound treatment 1393528.0 781000.0 3.49 1486953.0 932000.0 4.62 5.7351 0.9906 1973155 ChemDiv1_006107 COCCCN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(C)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F14 compound treatment 738599.0 126000.0 0.56 728455.0 173000.0 0.86 1.0052 0.979 1344065 ChemDiv1_006108 COc1ccc(O)c(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F15 compound treatment 755351.0 142000.0 0.64 745326.0 190000.0 0.94 1.1173 0.9819 1973156 ChemDiv1_006109 CCCCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F16 compound treatment 761679.0 149000.0 0.67 744654.0 190000.0 0.94 1.135 0.9859 1379296 ChemDiv1_006110 CCOC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F17 compound treatment 785024.0 172000.0 0.77 775440.0 220000.0 1.09 1.3167 0.9855 1500053 ChemDiv1_006111 CC(=O)Nc1ccc(Oc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F18 compound treatment 725722.0 113000.0 0.51 736181.0 181000.0 0.9 0.9915 0.9631 1973157 ChemDiv1_006112 CCOC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F19 compound treatment 741198.0 128000.0 0.57 760573.0 205000.0 1.02 1.1259 0.9633 1397533 ChemDiv1_006113 COC(=O)c1ccc(cc1)c2nnc(Nc3ccc(Cl)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F20 compound treatment 816971.0 204000.0 0.91 802564.0 247000.0 1.23 1.5129 0.9895 1924652 ChemDiv1_006114 Cc1csc(n1)c2cc3ccc(OC/C=C/c4ccccc4)cc3oc2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F21 compound treatment 745471.0 133000.0 0.59 732526.0 177000.0 0.88 1.0412 0.9817 1424194 ChemDiv1_006115 COC(=O)c1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F22 compound treatment 720287.0 107000.0 0.48 712132.0 157000.0 0.78 0.8901 0.9733 1372136 ChemDiv1_006116 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F23 mock treatment 724250.0 111000.0 0.5 674178.0 119000.0 0.59 0.7697 0.9965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 F24 mock treatment 574039.0 -38800.0 -0.17 509373.0 -45700.0 -0.23 -0.2831 -0.9915 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G01 compound treatment 633784.0 20900.0 0.09 576639.0 21500.0 0.11 0.1416 0.9979 1591908 ChemDiv1_006117 CCC(C)C(=O)N1C(C)CC(N(C(=O)c2cccc(Cl)c2)c3ccccc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G02 compound treatment 725748.0 113000.0 0.51 644569.0 89500.0 0.44 0.6707 0.9979 1620057 ChemDiv1_006118 O=c1n(C2CCCCC2)c(=S)[nH]c3sc4CCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G03 compound treatment 705994.0 93100.0 0.42 663524.0 108000.0 0.54 0.6745 0.9921 1446863 ChemDiv1_006119 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3c(C)cc(C)cc3C)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G04 compound treatment 733813.0 121000.0 0.54 698702.0 144000.0 0.71 0.8858 0.9909 1351010 ChemDiv1_006120 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G05 compound treatment 775452.0 163000.0 0.73 719884.0 165000.0 0.82 1.0918 0.9984 1385731 ChemDiv1_006121 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(C)cc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G06 compound treatment 745165.0 132000.0 0.59 687305.0 132000.0 0.65 0.8818 0.9987 1565498 ChemDiv1_006122 CCOC(=O)c1c(CSc2ccccc2)n(Cc3ccccc3)c4cc(Br)c(O)c(CN(C)C)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G07 compound treatment 766245.0 153000.0 0.69 712321.0 157000.0 0.78 1.0362 0.998 1402059 ChemDiv1_006123 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(C)cc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G08 compound treatment 762974.0 150000.0 0.67 723752.0 169000.0 0.84 1.0659 0.9942 1342061 ChemDiv1_006124 Oc1ccccc1C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G09 compound treatment 746775.0 134000.0 0.6 701206.0 146000.0 0.72 0.9356 0.9956 1124980 ChemDiv1_006125 CCOC(=O)Cn1c(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2C)nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G10 compound treatment 737043.0 124000.0 0.56 688742.0 134000.0 0.66 0.8612 0.9962 1973158 ChemDiv1_006126 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(Br)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G11 compound treatment 814386.0 202000.0 0.9 754813.0 200000.0 0.99 1.3374 0.9989 1973159 ChemDiv1_006127 COc1ccccc1OCCn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G12 compound treatment 758576.0 146000.0 0.65 741631.0 187000.0 0.92 1.1146 0.9855 1950533 ChemDiv1_006128 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G13 compound treatment 1041293.0 428000.0 1.92 797186.0 242000.0 1.2 2.2041 0.9744 1973160 ChemDiv1_006129 Oc1cccc(c1)n2c(/C=C/c3cc(Br)ccc3O)nc4ccccc4c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G14 compound treatment 758904.0 146000.0 0.65 717459.0 162000.0 0.8 1.031 0.9947 1425310 ChemDiv1_006130 COc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G15 compound treatment 806205.0 193000.0 0.87 757373.0 202000.0 1.0 1.3205 0.9973 1577022 ChemDiv1_006131 NC(=O)CSc1nc2sc3CCCCCc3c2c(=O)n1C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G16 compound treatment 760046.0 147000.0 0.66 725596.0 170000.0 0.84 1.0631 0.9924 1426969 ChemDiv1_006132 COc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G17 compound treatment 795929.0 183000.0 0.82 767092.0 212000.0 1.05 1.322 0.9925 1973161 ChemDiv1_006133 COc1ccc(cc1)n2c(SC)nc3sc4COC(C)(C)Cc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G18 compound treatment 764806.0 152000.0 0.68 701936.0 147000.0 0.73 0.9953 0.9994 1687208 ChemDiv1_006134 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G19 compound treatment 798069.0 185000.0 0.83 733992.0 179000.0 0.89 1.2128 0.9994 1973162 ChemDiv1_006135 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G20 compound treatment 734299.0 121000.0 0.54 732088.0 177000.0 0.88 1.0043 0.9736 1531762 ChemDiv1_006136 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G21 compound treatment 756506.0 144000.0 0.64 722488.0 167000.0 0.83 1.041 0.9921 1973163 ChemDiv1_006137 CC(=C)Cn1c(SCC(=C)Br)nc2sc3COC(C)(C)Cc3c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G22 compound treatment 754524.0 142000.0 0.63 700488.0 145000.0 0.72 0.9576 0.998 1708729 ChemDiv1_006138 COc1ccc(Nc2nc3nonc3nc2Nc4ccc(OC)cc4OC)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G23 mock treatment 748292.0 135000.0 0.61 678760.0 124000.0 0.61 0.8618 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 G24 mock treatment 352528.0 -260000.0 -1.17 491524.0 -63600.0 -0.31 -1.0468 -0.8671 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H01 compound treatment 629086.0 16200.0 0.07 579800.0 24700.0 0.12 0.1378 0.9689 1156675 ChemDiv1_006139 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H02 compound treatment 676457.0 63600.0 0.28 646972.0 91900.0 0.46 0.5231 0.9744 1973164 ChemDiv1_006140 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H03 compound treatment 688531.0 75700.0 0.34 669607.0 115000.0 0.57 0.6406 0.9696 1973165 ChemDiv1_006141 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCCN3CCOCC3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H04 compound treatment 693938.0 81100.0 0.36 683705.0 129000.0 0.64 0.7071 0.9644 1590418 ChemDiv1_006142 O=C(Cn1c(SCc2ccccc2)nc3ccccc13)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H05 compound treatment 733768.0 121000.0 0.54 721948.0 167000.0 0.83 0.9671 0.9789 1475097 ChemDiv1_006143 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4cccc(OC)c4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H06 compound treatment 717449.0 105000.0 0.47 711035.0 156000.0 0.77 0.8772 0.9712 1686613 ChemDiv1_006144 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H07 compound treatment 752852.0 140000.0 0.63 736879.0 182000.0 0.9 1.0798 0.9843 1690394 ChemDiv1_006145 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccc(C)cc5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H08 compound treatment 737696.0 125000.0 0.56 711328.0 156000.0 0.77 0.9423 0.9872 1973166 ChemDiv1_006146 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H09 compound treatment 719685.0 107000.0 0.48 736834.0 182000.0 0.9 0.9747 0.9562 1973167 ChemDiv1_006147 CC/1=NN(C(=O)\C1=C\NCCc2ccc(cc2)S(=O)(=O)N)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H10 compound treatment 726065.0 113000.0 0.51 738221.0 183000.0 0.91 0.9997 0.9621 1973168 ChemDiv1_006148 Cc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)ccc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H11 compound treatment 1663123.0 1050000.0 4.7 1640278.0 1090000.0 5.38 7.1256 0.9978 1973169 ChemDiv1_006149 COCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H12 compound treatment 722066.0 109000.0 0.49 699954.0 145000.0 0.72 0.853 0.9825 1973170 ChemDiv1_006150 O=C(Cn1c2ccccc2c(=O)c3ccccc13)NC(c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H13 compound treatment 1516209.0 903000.0 4.04 1553841.0 999000.0 4.95 6.3578 0.995 1973171 ChemDiv1_006151 CN1CCN(CC1)c2nc3c(C)cccn3c(=O)c2/C=C/4\SC(=S)N(CC5CCCO5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H14 compound treatment 754524.0 142000.0 0.63 737262.0 182000.0 0.9 1.0865 0.9851 1276069 ChemDiv1_006152 CCn1c2ccccc2c3cc(ccc13)C4C(=C(N)OC5=C4C(=O)CC(C)(C)C5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H15 compound treatment 751427.0 139000.0 0.62 744860.0 190000.0 0.94 1.1033 0.9796 1973172 ChemDiv1_006153 CCCCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H16 compound treatment 754312.0 141000.0 0.63 746896.0 192000.0 0.95 1.1195 0.9805 1438869 ChemDiv1_006154 CC(C)OC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H17 compound treatment 763619.0 151000.0 0.67 736216.0 181000.0 0.9 1.1116 0.9901 1437662 ChemDiv1_006155 COc1ccc(cc1)c2nnc(Oc3ccc(NC(=O)C)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H18 compound treatment 726185.0 113000.0 0.51 734383.0 179000.0 0.89 0.9867 0.9647 1973173 ChemDiv1_006156 CC(C)OC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H19 compound treatment 752975.0 140000.0 0.63 756352.0 201000.0 1.0 1.1484 0.975 1141217 ChemDiv1_006157 Cc1nc2cc(Nc3nnc(C)c4ccccc34)ccc2n1Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H20 compound treatment 699599.0 86700.0 0.39 708356.0 153000.0 0.76 0.8113 0.9515 1206829 ChemDiv1_006158 CCOC(=O)c1c(oc2cc(Br)c(OC(=O)c3ccco3)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H21 compound treatment 740271.0 127000.0 0.57 751632.0 197000.0 0.97 1.0917 0.9675 1230084 ChemDiv1_006159 Cc1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H22 compound treatment 705704.0 92800.0 0.42 716757.0 162000.0 0.8 0.8601 0.9533 1924787 ChemDiv1_006160 CCOC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H23 mock treatment 723327.0 110000.0 0.49 681253.0 126000.0 0.62 0.7915 0.9933 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 H24 mock treatment 624821.0 11900.0 0.05 494853.0 -60200.0 -0.3 -0.1732 -0.5713 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I01 compound treatment 648446.0 35600.0 0.16 591063.0 36000.0 0.18 0.2386 0.9984 1973174 ChemDiv1_006161 CCOc1ccc2N(C(=O)c3sc4ccccc4c3Cl)C(C)(C)C(=S)C(=C5SC(=C(S5)C(=O)OC)C(=O)OC)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I02 compound treatment 672178.0 59300.0 0.27 614607.0 59500.0 0.29 0.3962 0.9986 1397245 ChemDiv1_006162 CCC1(C)Cc2c(CO1)sc3[nH]c(=S)n(CC(=C)C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I03 compound treatment 713443.0 101000.0 0.45 649127.0 94000.0 0.47 0.6477 0.9999 1973175 ChemDiv1_006163 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I04 compound treatment 715676.0 103000.0 0.46 648918.0 93800.0 0.46 0.654 1.0 1973176 ChemDiv1_006164 CSc1nc(NC(C)(C)C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I05 compound treatment 760094.0 147000.0 0.66 728027.0 173000.0 0.86 1.0717 0.9916 1214687 ChemDiv1_006165 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3c(C)cc(C)cc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I06 compound treatment 717165.0 104000.0 0.47 668906.0 114000.0 0.56 0.7288 0.9956 1197848 ChemDiv1_006166 CCOC(=O)c1c(CN(CC)CC)n(C)c2c1cc(OC(=O)C)c3n(nc(c4ccccc4)c32)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I07 compound treatment 783576.0 171000.0 0.76 726929.0 172000.0 0.85 1.1422 0.9985 1403348 ChemDiv1_006167 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(C)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I08 compound treatment 758701.0 146000.0 0.65 740448.0 185000.0 0.92 1.1108 0.986 1585010 ChemDiv1_006168 COc1ccc(cc1OC)C(C#N)N2N=C(CC2c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I09 compound treatment 766641.0 154000.0 0.69 711333.0 156000.0 0.77 1.034 0.9983 1612433 ChemDiv1_006169 Cc1ccn2c(NC(=O)c3cccc(Br)c3)c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I10 compound treatment 744194.0 131000.0 0.59 707380.0 152000.0 0.75 0.9491 0.9924 1580047 ChemDiv1_006170 Brc1ccccc1Nc2ncnc3n(Cc4ccccc4)ncc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I11 compound treatment 791847.0 179000.0 0.8 751614.0 197000.0 0.97 1.2549 0.9953 1927342 ChemDiv1_006171 CCc1cc(C)cc(OCCn2cc(C=C3C(=O)NC(=S)NC3=O)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I12 compound treatment 756482.0 144000.0 0.64 728082.0 173000.0 0.86 1.0605 0.99 1485105 ChemDiv1_006172 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I13 compound treatment 751616.0 139000.0 0.62 718015.0 163000.0 0.81 1.0098 0.9916 1678216 ChemDiv1_006173 CC(C)(O)C#Cc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I14 compound treatment 758057.0 145000.0 0.65 724190.0 169000.0 0.84 1.0518 0.9921 1176339 ChemDiv1_006174 CC1=C(C(C2=C(CCCC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OC5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I15 compound treatment 792517.0 180000.0 0.8 732860.0 178000.0 0.88 1.1913 0.999 1236932 ChemDiv1_006175 CCSc1nc(NC(=O)N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I16 compound treatment 729624.0 117000.0 0.52 682032.0 127000.0 0.63 0.8142 0.9958 1973177 ChemDiv1_006176 CCOc1cc(cc([N+](=O)[O-])c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I17 compound treatment 793007.0 180000.0 0.81 739222.0 184000.0 0.91 1.2151 0.9981 1376789 ChemDiv1_006177 NC(=O)CSc1nc2sc3CCCCCc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I18 compound treatment 730912.0 118000.0 0.53 700824.0 146000.0 0.72 0.8841 0.9882 1635665 ChemDiv1_006178 CCOc1cc(ccc1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I19 compound treatment 756340.0 143000.0 0.64 720023.0 165000.0 0.82 1.0318 0.9929 1973178 ChemDiv1_006179 CCCCCOC(=O)CSc1nc(N)c2c3CC(C)(C)OCc3sc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I20 compound treatment 751638.0 139000.0 0.62 712632.0 158000.0 0.78 0.991 0.9936 1481422 ChemDiv1_006180 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I21 compound treatment 750458.0 138000.0 0.62 728082.0 173000.0 0.86 1.0414 0.9869 1345533 ChemDiv1_006181 COc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I22 compound treatment 763952.0 151000.0 0.68 690887.0 136000.0 0.67 0.9539 1.0 1423957 ChemDiv1_006182 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2cccc(NC(=O)c3cccc(c3)S(=O)(=O)N(CC)CC)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I23 mock treatment 739822.0 127000.0 0.57 678946.0 124000.0 0.61 0.8356 0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 I24 mock treatment 544936.0 -67900.0 -0.3 280712.0 -274000.0 -1.36 -1.1762 -0.8444 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J01 compound treatment 641872.0 29000.0 0.13 584897.0 29800.0 0.15 0.1962 0.9979 1533251 ChemDiv1_006183 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccc(NC(=O)c5ccc(OC(=O)C)cc5)cc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J02 compound treatment 665005.0 52100.0 0.23 641799.0 86700.0 0.43 0.4687 0.9589 1364665 ChemDiv1_006184 COc1ccccc1N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J03 compound treatment 719295.0 106000.0 0.48 663496.0 108000.0 0.54 0.7166 0.9982 1973179 ChemDiv1_006185 COc1ccc(CN/C=C\2/C(=O)N(N=C2CSc3ccc(C)cc3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J04 compound treatment 675632.0 62800.0 0.28 688055.0 133000.0 0.66 0.6644 0.9278 1973180 ChemDiv1_006186 OC(=O)C1CCN(CC1)S(=O)(=O)c2cc(ccc2Br)C(=O)Nc3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J05 compound treatment 721661.0 109000.0 0.49 695034.0 140000.0 0.69 0.8345 0.9851 1130618 ChemDiv1_006187 CCOc1ccc2N(C(=O)CSc3nnc(N)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J06 compound treatment 738797.0 126000.0 0.56 698712.0 144000.0 0.71 0.9016 0.9934 1269364 ChemDiv1_006188 COc1ccc(cc1)C(=O)Oc2cc(C=c3sc4nc5ccccc5n4c3=O)ccc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J07 compound treatment 729735.0 117000.0 0.52 752159.0 197000.0 0.98 1.0602 0.9572 1973181 ChemDiv1_006189 CCC(=O)N1C(C2=C(CC(CC2=O)c3cc(OC)c(OC)c(OC)c3)Nc4ccccc14)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J08 compound treatment 743763.0 131000.0 0.59 723181.0 168000.0 0.83 1.0031 0.9852 1973182 ChemDiv1_006190 Fc1ccc(cc1)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J09 compound treatment 750657.0 138000.0 0.62 727450.0 172000.0 0.85 1.0398 0.9873 1973183 ChemDiv1_006191 CCCC/1=NN(C(=O)\C1=C\NCc2ccc(OC)cc2)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J10 compound treatment 724926.0 112000.0 0.5 707396.0 152000.0 0.75 0.8882 0.9803 1973184 ChemDiv1_006192 COc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J11 compound treatment 1390356.0 777000.0 3.48 1385427.0 830000.0 4.11 5.3695 0.9965 1973185 ChemDiv1_006193 CC(C)CN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CC(C)OC(C)C4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J12 compound treatment 722672.0 110000.0 0.49 715666.0 161000.0 0.8 0.91 0.9732 1973186 ChemDiv1_006194 CCn1c2ccccc2c3cc(NC(=O)Cn4c5ccccc5c(=O)c6ccccc46)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J13 compound treatment 707173.0 94300.0 0.42 700488.0 145000.0 0.72 0.8078 0.9676 1973187 ChemDiv1_006195 CCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J14 compound treatment 732143.0 119000.0 0.53 731106.0 176000.0 0.87 0.994 0.9723 1700689 ChemDiv1_006196 COC(=O)C1=C(N)OC2=C(C1c3cccc(C)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J15 compound treatment 744699.0 132000.0 0.59 713121.0 158000.0 0.78 0.9708 0.9903 1420065 ChemDiv1_006197 CCN(CC)CCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J16 compound treatment 739947.0 127000.0 0.57 726005.0 171000.0 0.85 1.0009 0.9813 1924681 ChemDiv1_006198 COCCOC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J17 compound treatment 753888.0 141000.0 0.63 733060.0 178000.0 0.88 1.0697 0.9866 1536923 ChemDiv1_006199 CC(=O)Nc1cccc(Oc2nnc(c3ccc(C)cc3)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J18 compound treatment 727105.0 114000.0 0.51 727122.0 172000.0 0.85 0.9641 0.9701 1973188 ChemDiv1_006200 COCCOC(=O)c1c(C)oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J19 compound treatment 739925.0 127000.0 0.57 720927.0 166000.0 0.82 0.983 0.9839 1729995 ChemDiv1_006201 Cc1nc2cc(Nc3nnc(c4ccccc4)c5ccccc35)ccc2n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J20 compound treatment 704369.0 91500.0 0.41 711297.0 156000.0 0.77 0.8367 0.9558 1393926 ChemDiv1_006202 CCOC(=O)COc1cc2c(C(=O)OCC)c(oc2cc1Br)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J21 compound treatment 741756.0 129000.0 0.58 729392.0 174000.0 0.86 1.0185 0.9808 1407870 ChemDiv1_006203 Fc1cccc(c1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J22 compound treatment 708965.0 96100.0 0.43 670119.0 115000.0 0.57 0.7071 0.9904 1516219 ChemDiv1_006204 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J23 mock treatment 732237.0 119000.0 0.53 673097.0 118000.0 0.58 0.7911 0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 J24 mock treatment 561230.0 -51600.0 -0.23 206540.0 -349000.0 -1.73 -1.3844 -0.7947 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K01 compound treatment 643683.0 30800.0 0.14 565079.0 9980.0 0.05 0.1325 0.9043 1973189 ChemDiv1_006205 COC(=O)C1=C(SC(=C2C(=S)C(C)(C)N(C(=O)c3sc4ccccc4c3Cl)c5c(C)cccc25)S1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K02 compound treatment 691477.0 78600.0 0.35 633414.0 78300.0 0.39 0.5231 0.9988 1973190 ChemDiv1_006206 CCOC(=O)CSc1nc2sc3COC(C)(CC)Cc3c2c(=O)n1Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K03 compound treatment 729502.0 117000.0 0.52 671270.0 116000.0 0.58 0.7761 0.9988 1583069 ChemDiv1_006207 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(Br)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K04 compound treatment 704313.0 91400.0 0.41 651225.0 96100.0 0.48 0.6261 0.9972 1154521 ChemDiv1_006208 Cc1nc2scc(c3ccccc3)c2c(=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K05 compound treatment 710412.0 97500.0 0.44 669166.0 114000.0 0.57 0.7083 0.9919 1973191 ChemDiv1_006209 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cccc(c3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K06 compound treatment 720325.0 107000.0 0.48 695614.0 141000.0 0.7 0.8323 0.9837 1973192 ChemDiv1_006210 CCOC(=O)c1c(C)n(Cc2ccccc2)c3c1cc(O)c4n(nc(c5ccccc5)c43)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K07 compound treatment 782414.0 170000.0 0.76 698545.0 143000.0 0.71 1.0391 0.9995 1268068 ChemDiv1_006211 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(Cl)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K08 compound treatment 756204.0 143000.0 0.64 686502.0 131000.0 0.65 0.914 1.0 1925318 ChemDiv1_006212 Fc1c(F)c(c(F)c(F)c1N2C(=O)c3ccccc3S2(=O)=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K09 compound treatment 752019.0 139000.0 0.62 705085.0 150000.0 0.74 0.9658 0.9962 1722550 ChemDiv1_006213 CCCCC(=O)Nc1c(nc2cc(C)ccn12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K10 compound treatment 740828.0 128000.0 0.57 666618.0 112000.0 0.55 0.7956 0.9998 1626695 ChemDiv1_006214 Brc1ccc(Nc2ncnc3n(Cc4ccccc4)ncc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K11 compound treatment 781970.0 169000.0 0.76 740493.0 185000.0 0.92 1.1846 0.9954 1613089 ChemDiv1_006215 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OC(=O)c5ccccc5F)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K12 compound treatment 728324.0 115000.0 0.52 679836.0 125000.0 0.62 0.8024 0.9961 1695998 ChemDiv1_006216 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(cc5)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K13 compound treatment 742693.0 130000.0 0.58 724054.0 169000.0 0.84 1.0027 0.9841 1973193 ChemDiv1_006217 CCOC(=O)CSc1nc(N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K14 compound treatment 762503.0 150000.0 0.67 700000.0 145000.0 0.72 0.9812 0.9994 1668953 ChemDiv1_006218 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6c(Cl)cc(Cl)cc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K15 compound treatment 785279.0 172000.0 0.77 742493.0 187000.0 0.93 1.2021 0.9958 1530611 ChemDiv1_006219 COc1ccc(cc1)n2c(SCC(=O)O)nc3sc4CCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K16 compound treatment 731548.0 119000.0 0.53 696981.0 142000.0 0.7 0.8726 0.9905 1950497 ChemDiv1_006220 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc(O)c(c4)[N+](=O)[O-])C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K17 compound treatment 753287.0 140000.0 0.63 712668.0 158000.0 0.78 0.9964 0.9942 1973194 ChemDiv1_006221 CC(C)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K18 compound treatment 732877.0 120000.0 0.54 708992.0 154000.0 0.76 0.9189 0.9853 1950426 ChemDiv1_006222 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccccc5[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K19 compound treatment 799206.0 186000.0 0.83 714706.0 160000.0 0.79 1.1489 0.9996 1362292 ChemDiv1_006223 CC(=C)Cn1c(SCC(=O)N)nc2sc3COC(C)(C)Cc3c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K20 compound treatment 732420.0 120000.0 0.54 714039.0 159000.0 0.79 0.9351 0.9823 1135734 ChemDiv1_006224 CCOc1cc(cc(Br)c1O)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K21 compound treatment 790051.0 177000.0 0.79 757105.0 202000.0 1.0 1.2684 0.9934 1973195 ChemDiv1_006225 CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K22 compound treatment 743580.0 131000.0 0.59 690981.0 136000.0 0.67 0.8897 0.9976 1643471 ChemDiv1_006226 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2nnc(Cc3cccc(C)c3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K23 mock treatment 756251.0 143000.0 0.64 682505.0 127000.0 0.63 0.9001 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 K24 mock treatment 330617.0 -282000.0 -1.26 537873.0 -17200.0 -0.09 -0.9538 -0.7531 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L01 compound treatment 618615.0 5740.0 0.03 585624.0 30500.0 0.15 0.1251 0.8156 1615447 ChemDiv1_006227 CC(=O)Oc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4cc(NC(=O)c5ccc(OC(=O)C)cc5)ccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L02 compound treatment 645216.0 32300.0 0.14 606528.0 51400.0 0.25 0.2825 0.9641 1973196 ChemDiv1_006228 FC(F)(F)c1cc(ccc1Cl)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L03 compound treatment 688551.0 75700.0 0.34 640955.0 85900.0 0.43 0.5403 0.9936 1973197 ChemDiv1_006229 CCCCCCCCN/C=C\1/Sc2ccc(OCC)cc2C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L04 compound treatment 710108.0 97200.0 0.44 687456.0 132000.0 0.66 0.7714 0.9802 1973198 ChemDiv1_006230 Cc1ccc(cc1NS(=O)(=O)c2cc(C(=O)Nc3ccccc3)c(Cl)cc2Cl)S(=O)(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L05 compound treatment 727719.0 115000.0 0.51 713216.0 158000.0 0.78 0.9174 0.9791 1131778 ChemDiv1_006231 O=C(CCN1C(=O)c2ccccc2C1=O)N3c4ccccc4Sc5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L06 compound treatment 692141.0 79300.0 0.35 655950.0 101000.0 0.5 0.6042 0.9859 1973199 ChemDiv1_006232 [O-][N+](=O)c1cc(cc(c1)[N+](=O)[O-])C(=O)Nc2ccc3nc(NC(=O)C4CCCCC4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L07 compound treatment 728307.0 115000.0 0.52 721084.0 166000.0 0.82 0.9468 0.9749 1973200 ChemDiv1_006233 COc1ccc(cc1)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4cccc(Br)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L08 compound treatment 702538.0 89700.0 0.4 705998.0 151000.0 0.75 0.8124 0.9575 1973201 ChemDiv1_006234 O=c1oc(/C=C/c2ccccc2)nc3sc4CCCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L09 compound treatment 1393851.0 781000.0 3.5 1381476.0 826000.0 4.09 5.3667 0.9969 1973202 ChemDiv1_006235 CC(C)N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(Cc5ccccc5)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L10 compound treatment 729358.0 116000.0 0.52 669947.0 115000.0 0.57 0.771 0.9991 1973203 ChemDiv1_006236 COc1cc(OC)c(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L11 compound treatment 1075106.0 462000.0 2.07 1124421.0 569000.0 2.82 3.4574 0.9884 1973204 ChemDiv1_006237 CC(N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCCC4)/SC1=S)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L12 compound treatment 723615.0 111000.0 0.5 712410.0 157000.0 0.78 0.9016 0.9761 1973205 ChemDiv1_006238 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L13 compound treatment 734025.0 121000.0 0.54 700366.0 145000.0 0.72 0.8923 0.9903 1637527 ChemDiv1_006239 CCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L14 compound treatment 958542.0 346000.0 1.55 933148.0 378000.0 1.87 2.4184 0.9955 1973206 ChemDiv1_006240 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L15 compound treatment 736890.0 124000.0 0.56 712389.0 157000.0 0.78 0.9435 0.9862 1376814 ChemDiv1_006241 CCN(CC)CCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L16 compound treatment 8576102.0 7960000.0 35.65 8897089.0 8340000.0 41.32 54.4267 0.9973 1488976 ChemDiv1_006242 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1CN5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L17 compound treatment 729182.0 116000.0 0.52 738848.0 184000.0 0.91 1.0118 0.9649 1151091 ChemDiv1_006243 CC(=O)Nc1cccc(Oc2nnc(c3ccc(Cl)cc3)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L18 compound treatment 726843.0 114000.0 0.51 705709.0 151000.0 0.75 0.8883 0.9828 1973207 ChemDiv1_006244 COCCOC(=O)c1c(C)oc2ccc(OCc3ccc(cc3)c4cnc(o4)c5ccccc5)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L19 compound treatment 730989.0 118000.0 0.53 697405.0 142000.0 0.7 0.8723 0.9899 1208565 ChemDiv1_006245 COc1ccc(cc1)c2nnc(Nc3ccc4n(C)cnc4c3)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L20 compound treatment 731637.0 119000.0 0.53 712763.0 158000.0 0.78 0.9282 0.9824 1924846 ChemDiv1_006246 COC(=O)c1c(C)oc2cc(Br)c(OC(=O)c3ccc(cc3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L21 compound treatment 759101.0 146000.0 0.65 711496.0 156000.0 0.77 1.0107 0.9965 1138961 ChemDiv1_006247 Fc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L22 compound treatment 701129.0 88300.0 0.4 685132.0 130000.0 0.64 0.7348 0.9725 1925014 ChemDiv1_006248 COC(=O)c1c(C)oc2cc(Br)c(OCc3ccc(cc3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L23 mock treatment 733361.0 120000.0 0.54 670049.0 115000.0 0.57 0.784 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 L24 mock treatment 601248.0 -11600.0 -0.05 385526.0 -170000.0 -0.84 -0.6308 -0.7495 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M01 compound treatment 655918.0 43000.0 0.19 592388.0 37300.0 0.18 0.2669 0.9998 1973208 ChemDiv1_006249 CC1CC(N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc4)c5ccccc5N1C(=O)CN6C(=O)c7ccccc7C6=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M02 compound treatment 676243.0 63400.0 0.28 634555.0 79500.0 0.39 0.4789 0.9871 1973209 ChemDiv1_006250 CCC1(C)Cc2c(CO1)sc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M03 compound treatment 746966.0 134000.0 0.6 670809.0 116000.0 0.57 0.8298 0.9997 1720942 ChemDiv1_006251 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(Cl)ccc3Cl)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M04 compound treatment 708913.0 96000.0 0.43 644397.0 89300.0 0.44 0.6168 0.9999 1973210 ChemDiv1_006252 CCCN1C(=O)C(CC(=O)C)(OC(=O)C)c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M05 compound treatment 750270.0 137000.0 0.62 672215.0 117000.0 0.58 0.8451 0.9996 1250181 ChemDiv1_006253 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M06 compound treatment 725929.0 113000.0 0.51 675931.0 121000.0 0.6 0.7811 0.9965 1464524 ChemDiv1_006254 CCOC(=O)c1c(C)[nH]c2c1cc(O)c3n(nc(c4ccccc4)c23)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M07 compound treatment 764430.0 152000.0 0.68 714008.0 159000.0 0.79 1.0364 0.9973 1485619 ChemDiv1_006255 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(CC)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M08 compound treatment 736176.0 123000.0 0.55 662849.0 108000.0 0.53 0.7677 0.9999 1973211 ChemDiv1_006256 FC(F)(F)c1cc(nc(SCC(=O)N2CCOCC2)c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M09 compound treatment 757498.0 145000.0 0.65 687623.0 133000.0 0.66 0.922 1.0 1333769 ChemDiv1_006257 Brc1ccccc1C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M10 compound treatment 729932.0 117000.0 0.52 670091.0 115000.0 0.57 0.7733 0.9991 1614418 ChemDiv1_006258 O=c1oc(nc2sc3CCCCCc3c12)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M11 compound treatment 782274.0 169000.0 0.76 680546.0 125000.0 0.62 0.9756 0.9951 1443565 ChemDiv1_006259 CCCCc1ccc(cc1)C(=O)On2c(nc3ccccc3c2=O)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M12 compound treatment 725274.0 112000.0 0.5 666849.0 112000.0 0.55 0.7472 0.9989 1466674 ChemDiv1_006260 Cc1ccc2occ(C3Nc4cc(C)c(C)cc4NC5=C3C(=O)CC(C)(C)C5)c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M13 compound treatment 795260.0 182000.0 0.82 658003.0 103000.0 0.51 0.9378 0.9743 1691214 ChemDiv1_006261 COC(=O)CSc1nc(N)c2c3CCC(Cc3sc2n1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M14 compound treatment 751860.0 139000.0 0.62 694388.0 139000.0 0.69 0.9278 0.9987 1950435 ChemDiv1_006262 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(ccc5Cl)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M15 compound treatment 769576.0 157000.0 0.7 742218.0 187000.0 0.93 1.1515 0.9905 1973212 ChemDiv1_006263 COC(=O)CSc1nnc2n(c3ccc(OC)cc3)c(=O)c4c5CCCCCc5sc4n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M16 compound treatment 739363.0 126000.0 0.57 698343.0 143000.0 0.71 0.9021 0.9937 1973213 ChemDiv1_006264 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M17 compound treatment 742887.0 130000.0 0.58 691105.0 136000.0 0.67 0.8879 0.9973 1973214 ChemDiv1_006265 CCCCCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M18 compound treatment 772113.0 159000.0 0.71 713110.0 158000.0 0.78 1.0575 0.9989 1950470 ChemDiv1_006266 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cccc(c5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M19 compound treatment 794057.0 181000.0 0.81 744826.0 190000.0 0.94 1.2381 0.9973 1973215 ChemDiv1_006267 CCOC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M20 compound treatment 766720.0 154000.0 0.69 687407.0 132000.0 0.66 0.9504 0.9997 1973216 ChemDiv1_006268 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC)c(OC)c5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M21 compound treatment 822501.0 210000.0 0.94 725503.0 170000.0 0.84 1.2604 0.9986 1933595 ChemDiv1_006269 CN1CCc2c(C1)sc3[nH]c(=S)n(CCc4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M22 compound treatment 734043.0 121000.0 0.54 684146.0 129000.0 0.64 0.8356 0.9967 1680463 ChemDiv1_006270 Clc1ccc(OCc2nnc(NC(=O)c3cccc(c3)S(=O)(=O)N4CCOCC4)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M23 mock treatment 737081.0 124000.0 0.56 689831.0 135000.0 0.67 0.8651 0.9959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 M24 mock treatment 473789.0 -139000.0 -0.62 406380.0 -149000.0 -0.74 -0.9612 -0.9965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N01 compound treatment 626343.0 13500.0 0.06 575553.0 20500.0 0.1 0.1143 0.9692 1169903 ChemDiv1_006271 COc1ccccc1NC(=O)CSc2nc3CCCCc3cc2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N02 compound treatment 656816.0 43900.0 0.2 619131.0 64000.0 0.32 0.3634 0.9736 1679313 ChemDiv1_006272 CCOc1ccccc1N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N03 compound treatment 718796.0 106000.0 0.47 671625.0 117000.0 0.58 0.7434 0.9952 1973217 ChemDiv1_006273 CCOc1ccc2S/C(=C/NCCCOC)/C(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N04 compound treatment 714897.0 102000.0 0.46 657600.0 103000.0 0.51 0.682 0.9986 1973218 ChemDiv1_006274 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1OCc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N05 compound treatment 730912.0 118000.0 0.53 692225.0 137000.0 0.68 0.854 0.9923 1973219 ChemDiv1_006275 CC(N1C(=O)C2CCCCC2C1=O)C(=O)N3c4ccccc4C(C)(CC3(C)C)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N06 compound treatment 724283.0 111000.0 0.5 700341.0 145000.0 0.72 0.8614 0.984 1323093 ChemDiv1_006276 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N07 compound treatment 738934.0 126000.0 0.56 696548.0 141000.0 0.7 0.8945 0.9942 1660389 ChemDiv1_006277 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccccc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N08 compound treatment 685804.0 72900.0 0.33 670030.0 115000.0 0.57 0.6334 0.9651 1973220 ChemDiv1_006278 O=C(Cn1c2ccccc2c(=O)c3ccccc13)Nc4ccc(Oc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N09 compound treatment 1768993.0 1160000.0 5.18 1710381.0 1160000.0 5.72 7.7062 0.9987 1973221 ChemDiv1_006279 COCCCN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCN(Cc5ccccc5)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N10 compound treatment 683933.0 71100.0 0.32 680105.0 125000.0 0.62 0.6628 0.9521 1322065 ChemDiv1_006280 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N11 compound treatment 974447.0 362000.0 1.62 888923.0 334000.0 1.65 2.3138 0.9999 1973222 ChemDiv1_006281 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCc4ccccc4)C3=O)c(nc12)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N12 compound treatment 679855.0 67000.0 0.3 668295.0 113000.0 0.56 0.6085 0.957 1973223 ChemDiv1_006282 COc1cc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N13 compound treatment 714685.0 102000.0 0.46 660101.0 105000.0 0.52 0.6901 0.9978 1973224 ChemDiv1_006283 CCCOc1nnc(c2ccc(C)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N14 compound treatment 3.8998036E7 3.84E7 171.83 3.786544E7 3.73E7 184.83 252.1929 0.9993 1723325 ChemDiv1_006284 Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1CN5CCCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N15 compound treatment 736221.0 123000.0 0.55 690146.0 135000.0 0.67 0.8635 0.9955 1589686 ChemDiv1_006285 CCN(CC)CCOc1nnc(c2ccc(OC)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N16 compound treatment 719680.0 107000.0 0.48 678455.0 123000.0 0.61 0.7702 0.9926 1924822 ChemDiv1_006286 COCCOC(=O)c1c(C)oc2ccc(OCc3c(F)c(F)c(F)c(F)c3F)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N17 compound treatment 708913.0 96000.0 0.43 715868.0 161000.0 0.8 0.8671 0.9581 1163825 ChemDiv1_006287 COc1ccc(cc1)c2nnc(Oc3cccc(NC(=O)C)c3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N18 compound treatment 732121.0 119000.0 0.53 677493.0 122000.0 0.61 0.8062 0.998 1925060 ChemDiv1_006288 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3sc4ccccc4c3Cl)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N19 compound treatment 759424.0 147000.0 0.66 699543.0 144000.0 0.72 0.9698 0.9991 1403706 ChemDiv1_006289 CCOC(=O)Cc1nnc(Nc2ccc(C)cc2C)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N20 compound treatment 734858.0 122000.0 0.55 699072.0 144000.0 0.71 0.8904 0.9913 1265136 ChemDiv1_006290 COC(=O)c1c(C)oc2cc(Br)c(OC(=O)c3ccc(Cl)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N21 compound treatment 741608.0 129000.0 0.58 709252.0 154000.0 0.76 0.9475 0.9904 1973225 ChemDiv1_006291 Cc1ccc(cc1)N(CCCCN2C(=O)c3ccccc3C2=O)C(=O)c4sc5ccccc5c4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N22 compound treatment 707749.0 94900.0 0.42 658690.0 104000.0 0.51 0.6632 0.9956 1489880 ChemDiv1_006292 COC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OCc3ccccc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N23 mock treatment 715417.0 103000.0 0.46 664205.0 109000.0 0.54 0.7068 0.9967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 N24 mock treatment 245610.0 -367000.0 -1.64 385432.0 -170000.0 -0.84 -1.7568 -0.9515 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O01 compound treatment 651181.0 38300.0 0.17 579518.0 24400.0 0.12 0.2068 0.9854 1304134 ChemDiv1_006293 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CC(Nc4ccccc4)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O02 compound treatment 660924.0 48000.0 0.22 596907.0 41800.0 0.21 0.2985 0.9998 1418791 ChemDiv1_006294 O=C(CSc1nnc2n(Cc3ccccc3)c(=O)c4c5CCCCc5sc4n12)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O03 compound treatment 711675.0 98800.0 0.44 660648.0 106000.0 0.52 0.6825 0.9965 1669254 ChemDiv1_006295 CC(C)OC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O04 compound treatment 679774.0 66900.0 0.3 623427.0 68300.0 0.34 0.4511 0.9981 1446958 ChemDiv1_006296 O=C1NCCc2c1[nH]c3ccc(cc23)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O05 compound treatment 689776.0 76900.0 0.34 642757.0 87700.0 0.43 0.5505 0.9934 1973226 ChemDiv1_006297 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O06 compound treatment 690877.0 78000.0 0.35 653493.0 98400.0 0.49 0.5916 0.9866 1333062 ChemDiv1_006298 CCOC(=O)c1c(C)n(C)c2c1cc(OC(=O)C)c3n(nc(c4ccccc4)c32)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O07 compound treatment 730269.0 117000.0 0.53 680834.0 126000.0 0.62 0.812 0.9964 1569005 ChemDiv1_006299 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(CC)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O08 compound treatment 736912.0 124000.0 0.56 675680.0 121000.0 0.6 0.815 0.9993 1973227 ChemDiv1_006300 COc1ccc(cc1)c2cc(nc(SCC(=O)C)c2C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O09 compound treatment 729055.0 116000.0 0.52 681883.0 127000.0 0.63 0.8119 0.9956 1413740 ChemDiv1_006301 OC(=O)c1ccccc1C(=O)Nc2c(nc3ccccn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O10 compound treatment 709081.0 96200.0 0.43 626355.0 71300.0 0.35 0.5541 0.9951 1926925 ChemDiv1_006302 Clc1ccccc1c2nc3sc4CCCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O11 compound treatment 749176.0 136000.0 0.61 685278.0 130000.0 0.64 0.8874 0.9996 1973228 ChemDiv1_006303 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2OC(=O)/C=C/c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O12 compound treatment 726765.0 114000.0 0.51 614568.0 59500.0 0.29 0.5688 0.966 1289428 ChemDiv1_006304 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O13 compound treatment 1663579.0 1050000.0 4.7 1459820.0 905000.0 4.48 6.4949 0.9997 1973229 ChemDiv1_006305 CN1CCc2c(C1)sc3[nH]c(=S)n(C4CCCCC4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O14 compound treatment 714971.0 102000.0 0.46 669385.0 114000.0 0.57 0.7235 0.9944 1524157 ChemDiv1_006306 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O15 compound treatment 873123.0 260000.0 1.16 789741.0 235000.0 1.16 1.6457 1.0 1932186 ChemDiv1_006307 COc1ccc(cc1)n2c(=O)c3c4CCN(Cc5ccccc5)Cc4sc3[nH]c2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O16 compound treatment 725361.0 112000.0 0.5 664813.0 110000.0 0.54 0.7404 0.9993 1657539 ChemDiv1_006308 CC1=C(C(NC(=O)N1)c2ccccc2OCc3ccccc3)C(=O)OCc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O17 compound treatment 794815.0 182000.0 0.81 771231.0 216000.0 1.07 1.333 0.9909 1973230 ChemDiv1_006309 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CC(C)(C)OCc3sc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O18 compound treatment 709978.0 97100.0 0.43 664772.0 110000.0 0.54 0.6915 0.9939 1973231 ChemDiv1_006310 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O19 compound treatment 765473.0 153000.0 0.68 707375.0 152000.0 0.75 1.0164 0.9988 1973232 ChemDiv1_006311 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O20 compound treatment 728818.0 116000.0 0.52 679334.0 124000.0 0.62 0.8022 0.9964 1432771 ChemDiv1_006312 COc1cc(Nc2nc3nonc3nc2N4CCCCC4C)c(OC)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O21 compound treatment 728439.0 116000.0 0.52 692369.0 137000.0 0.68 0.8466 0.9909 1374638 ChemDiv1_006313 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O22 compound treatment 696946.0 84100.0 0.38 646101.0 91000.0 0.45 0.5849 0.996 1058931 ChemDiv1_006314 CC(=O)N1C(=O)C2(Nc3ccccc3N2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O23 mock treatment 726908.0 114000.0 0.51 657977.0 103000.0 0.51 0.7213 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 O24 mock treatment 416776.0 -196000.0 -0.88 429967.0 -125000.0 -0.62 -1.059 -0.9855 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P01 compound treatment 590416.0 -22500.0 -0.1 542479.0 -12600.0 -0.06 -0.1153 -0.9739 1973233 ChemDiv1_006315 COc1ccccc1NC(=O)CSc2nc3CCCCCc3cc2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P02 compound treatment 630023.0 17100.0 0.08 573428.0 18300.0 0.09 0.1185 0.9965 1604831 ChemDiv1_006316 COc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4ccc5OCCOc5c4)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P03 compound treatment 625019.0 12100.0 0.05 580316.0 25200.0 0.12 0.1268 0.9305 1973234 ChemDiv1_006317 CCCCCCCCCN/C=C\1/Sc2ccc(OCC)cc2C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P04 compound treatment 636859.0 24000.0 0.11 595852.0 40800.0 0.2 0.2187 0.9563 1973235 ChemDiv1_006318 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OCc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P05 compound treatment 638427.0 25600.0 0.11 592952.0 37900.0 0.19 0.2135 0.9719 1543744 ChemDiv1_006319 O=C(CCN1C(=O)c2ccccc2C1=O)N3CCCc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P06 compound treatment 729905.0 117000.0 0.52 640253.0 85200.0 0.42 0.6687 0.9942 1973236 ChemDiv1_006320 Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1c5ccc(cc5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P07 compound treatment 695674.0 82800.0 0.37 612679.0 57600.0 0.29 0.4638 0.9916 1973237 ChemDiv1_006321 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)OC(=C(C#N)C3c4ccc(cc4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P08 compound treatment 667407.0 54500.0 0.24 610133.0 55000.0 0.27 0.3654 0.9985 1973238 ChemDiv1_006322 FC(F)(F)Oc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P09 compound treatment 965930.0 353000.0 1.58 840332.0 285000.0 1.41 2.1167 0.9984 1973239 ChemDiv1_006323 CC(N1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCC(C)CC4)/SC1=S)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P10 compound treatment 692425.0 79500.0 0.36 603138.0 48000.0 0.24 0.4201 0.9808 1565833 ChemDiv1_006324 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P11 compound treatment 790453.0 178000.0 0.79 686249.0 131000.0 0.65 1.0215 0.995 1973240 ChemDiv1_006325 CC(C)N1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N(C)Cc4ccccc4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P12 compound treatment 698212.0 85300.0 0.38 590231.0 35100.0 0.17 0.3932 0.9366 1589589 ChemDiv1_006326 COc1ccc(OC)c(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P13 compound treatment 662908.0 50000.0 0.22 605337.0 50200.0 0.25 0.3343 0.9986 1973241 ChemDiv1_006327 CCCOc1nnc(c2ccc(Cl)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P14 compound treatment 2.3087138E7 2.25E7 100.6 2.1540178E7 2.1E7 103.96 144.6453 0.9999 1173746 ChemDiv1_006328 CC1CCCCN1Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P15 compound treatment 686199.0 73300.0 0.33 613556.0 58500.0 0.29 0.4369 0.9981 1137124 ChemDiv1_006329 COc1ccc(cc1)c2nnc(Sc3nc4ccccc4o3)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P16 compound treatment 693639.0 80800.0 0.36 625136.0 70000.0 0.35 0.501 0.9998 1973242 ChemDiv1_006330 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P17 compound treatment 710663.0 97800.0 0.44 624230.0 69100.0 0.34 0.5517 0.9926 1568255 ChemDiv1_006331 COc1ccc(cc1)c2nnc(Oc3ccc(C)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P18 compound treatment 917791.0 305000.0 1.36 761570.0 206000.0 1.02 1.6884 0.9899 1639090 ChemDiv1_006332 O=c1oc2cc(OCC#N)ccc2cc1c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P19 compound treatment 704097.0 91200.0 0.41 628213.0 73100.0 0.36 0.5449 0.9982 1262359 ChemDiv1_006333 CCOC(=O)Cc1nnc(Nc2cc(C)ccc2C)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P20 compound treatment 682568.0 69700.0 0.31 630797.0 75700.0 0.38 0.4858 0.9958 1217075 ChemDiv1_006334 COC(=O)c1c(C)oc2cc(Br)c(OCC(=O)c3ccc(OC)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P21 compound treatment 669934.0 57100.0 0.26 593346.0 38200.0 0.19 0.3146 0.9892 1943504 ChemDiv1_006335 OC(=O)c1cccnc1SC2CC(=O)N(C2=O)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P22 compound treatment 637457.0 24600.0 0.11 600918.0 45800.0 0.23 0.2383 0.9447 1646668 ChemDiv1_006336 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OC(C)(C)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P23 mock treatment 673148.0 60300.0 0.27 572730.0 17600.0 0.09 0.2525 0.8905 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.604 P24 mock treatment 435882.0 -177000.0 -0.79 430134.0 -125000.0 -0.62 -0.998 -0.9925 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A01 compound treatment 605314.0 21600.0 0.1 232293.0 -330000.0 -1.64 -1.0888 -0.6642 1259095 ChemDiv1_006337 CCOC(=O)c1c(C)oc2cc(Br)c(OCC(=O)OC(C)(C)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A02 compound treatment 589244.0 5520.0 0.02 535321.0 -27300.0 -0.14 -0.0782 -0.5686 1252103 ChemDiv1_006338 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4coc5ccc(C)cc5c4=O)C(=O)CCC3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A03 compound treatment 599127.0 15400.0 0.07 548836.0 -13800.0 -0.07 4.0E-4 0.0043 1437380 ChemDiv1_006339 CCOc1ccc2nc(SCc3c(nnn3c4nonc4N)C(=O)OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A04 compound treatment 605812.0 22100.0 0.1 549467.0 -13200.0 -0.07 0.0238 0.2008 1631298 ChemDiv1_006340 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2C)C(=O)Nc3ccccc3C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A05 compound treatment 618789.0 35100.0 0.16 580365.0 17700.0 0.09 0.1731 0.9624 1973243 ChemDiv1_006341 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A06 compound treatment 604154.0 20400.0 0.09 560659.0 -1980.0 -0.01 0.0577 0.6278 1151558 ChemDiv1_006342 Fc1ccc(Br)cc1C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A07 compound treatment 632340.0 48600.0 0.22 585881.0 23200.0 0.12 0.2353 0.9557 1973244 ChemDiv1_006343 COc1ccccc1OCCOc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A08 compound treatment 647489.0 63800.0 0.29 587622.0 25000.0 0.12 0.2894 0.9301 1973245 ChemDiv1_006344 COC(=O)c1ccc(cc1)n2c(C)cc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A09 compound treatment 631623.0 47900.0 0.21 587687.0 25100.0 0.12 0.2394 0.9662 1664018 ChemDiv1_006345 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A10 compound treatment 628668.0 44900.0 0.2 580281.0 17600.0 0.09 0.2041 0.9303 1973246 ChemDiv1_006346 CC(=O)Nc1ccc2nc(SCc3c(Cl)cccc3[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A11 compound treatment 760465.0 177000.0 0.79 598540.0 35900.0 0.18 0.6852 0.845 1676253 ChemDiv1_006347 CC(=O)Nc1nc2[nH]c(C)c(Cc3ccccc3)c(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A12 compound treatment 614744.0 31000.0 0.14 608264.0 45600.0 0.23 0.258 0.9726 1973247 ChemDiv1_006348 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Cl)ccc4O)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A13 compound treatment 747139.0 163000.0 0.73 734992.0 172000.0 0.85 1.121 0.997 1973248 ChemDiv1_006349 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A14 compound treatment 671733.0 88000.0 0.39 642286.0 79700.0 0.39 0.5576 1.0 1973249 ChemDiv1_006350 Clc1cccc(c1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4nccs4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A15 compound treatment 650572.0 66800.0 0.3 606856.0 44200.0 0.22 0.3665 0.9882 1223853 ChemDiv1_006351 Cn1cnnc1Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cc5OCOc5cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A16 compound treatment 654859.0 71100.0 0.32 600731.0 38100.0 0.19 0.3586 0.9688 1573956 ChemDiv1_006352 Cc1cccc(NC(=O)c2ccc3OCCOc3c2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A17 compound treatment 663182.0 79500.0 0.36 618595.0 56000.0 0.28 0.4475 0.9924 1933212 ChemDiv1_006353 [O-][N+](=O)c1ccccc1c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A18 compound treatment 631900.0 48200.0 0.22 595062.0 32400.0 0.16 0.2661 0.9895 1642975 ChemDiv1_006354 Cn1c(Sc2nc3ccccc3n2CC(=O)N4CCOCC4)nc5n(C)c(=O)n(C)c(=O)c15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A19 compound treatment 639629.0 55900.0 0.25 602077.0 39400.0 0.2 0.3151 0.9925 1941979 ChemDiv1_006355 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A20 compound treatment 639743.0 56000.0 0.25 581814.0 19200.0 0.1 0.2445 0.9118 1973250 ChemDiv1_006356 Brc1cc(/C=C/2\NC(=S)NC2=O)cc(Br)c1OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A21 compound treatment 697798.0 114000.0 0.51 659487.0 96900.0 0.48 0.7003 0.9995 1973251 ChemDiv1_006357 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)c(Br)cc1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A22 compound treatment 604336.0 20600.0 0.09 566456.0 3820.0 0.02 0.0786 0.8348 1324877 ChemDiv1_006358 COc1ccc(Cl)cc1NC(=O)CSc2nc3ccccc3[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A23 mock treatment 595235.0 11500.0 0.05 569008.0 6370.0 0.03 0.0588 0.9724 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 A24 mock treatment 514439.0 -69300.0 -0.31 488875.0 -73800.0 -0.37 -0.4777 -0.9967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B01 compound treatment 623093.0 39400.0 0.18 598930.0 36300.0 0.18 0.2517 0.9999 1132172 ChemDiv1_006359 COc1ccc2[nH]c(SCC(=O)Nc3cc(Cl)ccc3OC)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B02 compound treatment 655642.0 71900.0 0.32 591448.0 28800.0 0.14 0.3286 0.933 1150303 ChemDiv1_006360 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(F)cc4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B03 compound treatment 694488.0 111000.0 0.5 640261.0 77600.0 0.38 0.6225 0.9921 1587603 ChemDiv1_006361 Cc1nnc(SCC(=O)Nc2cc(NC(=O)CSc3nnc(C)s3)cc(c2)C(=O)O)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B04 compound treatment 671097.0 87400.0 0.39 622378.0 59700.0 0.3 0.4858 0.9905 1464077 ChemDiv1_006362 Clc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B05 compound treatment 756755.0 173000.0 0.77 698986.0 136000.0 0.68 1.0253 0.9977 1360101 ChemDiv1_006363 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC(=O)c3ccc(Cl)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B06 compound treatment 692921.0 109000.0 0.49 624347.0 61700.0 0.31 0.5618 0.9745 1645183 ChemDiv1_006364 COc1ccc(cc1CSc2nc3ccccc3o2)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B07 compound treatment 702083.0 118000.0 0.53 671742.0 109000.0 0.54 0.7568 1.0 1466415 ChemDiv1_006365 CCNc1nc(NC(C)C)nc(Oc2ccccc2C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B08 compound treatment 714616.0 131000.0 0.59 661649.0 99000.0 0.49 0.7611 0.9961 1573223 ChemDiv1_006366 CCOc1cc(ccc1OCc2ccccc2Cl)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B09 compound treatment 695288.0 112000.0 0.5 676642.0 114000.0 0.56 0.7525 0.9981 1410139 ChemDiv1_006367 Clc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B10 compound treatment 701338.0 118000.0 0.53 676191.0 114000.0 0.56 0.77 0.9995 1341472 ChemDiv1_006368 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4cccc(OC)c4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B11 compound treatment 731007.0 147000.0 0.66 689845.0 127000.0 0.63 0.9118 0.9997 1973252 ChemDiv1_006369 COCc1cc(C)nc2sc(c(NC(=O)c3ccccc3)c12)c4ccc(o4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B12 compound treatment 686058.0 102000.0 0.46 669416.0 107000.0 0.53 0.698 0.9974 1155668 ChemDiv1_006370 COc1cc(CNn2c(nc3ccccc3c2=O)c4ccc(Br)cc4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B13 compound treatment 752277.0 169000.0 0.75 710799.0 148000.0 0.73 1.0525 0.9999 1973253 ChemDiv1_006371 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N4CCCc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B14 compound treatment 722590.0 139000.0 0.62 683280.0 121000.0 0.6 0.8621 0.9998 1973254 ChemDiv1_006372 Clc1cccc(c1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B15 compound treatment 714066.0 130000.0 0.58 712326.0 150000.0 0.74 0.9369 0.993 1973255 ChemDiv1_006373 CC(C)Cc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B16 compound treatment 701731.0 118000.0 0.53 701751.0 139000.0 0.69 0.8608 0.9914 1973256 ChemDiv1_006374 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Oc5ccc(F)cc5F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B17 compound treatment 742099.0 158000.0 0.71 705771.0 143000.0 0.71 1.0027 1.0 1973257 ChemDiv1_006375 CCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B18 compound treatment 699310.0 116000.0 0.52 670096.0 107000.0 0.53 0.7423 0.9999 1628108 ChemDiv1_006376 Fc1cccc(Cl)c1Cc2nc3ccccc3[nH]c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B19 compound treatment 728066.0 144000.0 0.65 678040.0 115000.0 0.57 0.8611 0.9981 1973258 ChemDiv1_006377 CCN(CC)Cc1c(O)ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc12)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B20 compound treatment 705142.0 121000.0 0.54 652441.0 89800.0 0.44 0.6989 0.9951 1302671 ChemDiv1_006378 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2nc(cs2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B21 compound treatment 717437.0 134000.0 0.6 664863.0 102000.0 0.51 0.7813 0.9965 1973259 ChemDiv1_006379 COc1ccc(cc1OC)c2c(oc3c(CN4CC(C)OC(C)C4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B22 compound treatment 653935.0 70200.0 0.31 641624.0 79000.0 0.39 0.4989 0.9941 1973260 ChemDiv1_006380 Cc1cc(C)c(C#N)c(SCC(=O)Nc2c(Cl)cccc2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B23 mock treatment 684597.0 101000.0 0.45 623085.0 60400.0 0.3 0.531 0.9801 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 B24 mock treatment 508850.0 -74900.0 -0.34 528227.0 -34400.0 -0.17 -0.3575 -0.9508 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C01 compound treatment 610651.0 26900.0 0.12 566074.0 3440.0 0.02 0.0973 0.7991 1924863 ChemDiv1_006381 COCCOC(=O)c1c(C)oc2ccc(OCc3ccccc3Br)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C02 compound treatment 663223.0 79500.0 0.36 579703.0 17100.0 0.08 0.3114 0.8514 1634153 ChemDiv1_006382 CCCOc1ccc(cc1OC)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C03 compound treatment 670213.0 86500.0 0.39 620094.0 57500.0 0.28 0.475 0.9886 1973261 ChemDiv1_006383 COC(=O)c1nnn(c1CSc2nc3cc(ccc3[nH]2)[N+](=O)[O-])c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C04 compound treatment 657810.0 74100.0 0.33 611653.0 49000.0 0.24 0.4062 0.9883 1426575 ChemDiv1_006384 COc1ccc(cc1Br)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C05 compound treatment 701716.0 118000.0 0.53 654233.0 91600.0 0.45 0.6943 0.9971 1973262 ChemDiv1_006385 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C06 compound treatment 648678.0 65000.0 0.29 621837.0 59200.0 0.29 0.413 1.0 1256855 ChemDiv1_006386 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2C)C(=O)Nc3ccccc3C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C07 compound treatment 703020.0 119000.0 0.53 649655.0 87000.0 0.43 0.6824 0.9944 1973263 ChemDiv1_006387 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCCOCCOc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C08 compound treatment 694853.0 111000.0 0.5 656445.0 93800.0 0.46 0.6804 0.9994 1973264 ChemDiv1_006388 Cc1cc(ccc1Br)N2C(=O)NC(=O)/C(=C/c3ccccc3OCC#N)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C09 compound treatment 955797.0 372000.0 1.67 920032.0 357000.0 1.77 2.4296 0.9995 1251189 ChemDiv1_006389 Cc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)c1C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C10 compound treatment 709565.0 126000.0 0.56 676523.0 114000.0 0.56 0.7973 1.0 1973265 ChemDiv1_006390 [O-][N+](=O)c1cc2OCOc2cc1/C=C/3\SC(=N)N(C3=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C11 compound treatment 681502.0 97800.0 0.44 658228.0 95600.0 0.47 0.6443 0.9992 1973266 ChemDiv1_006391 CC(=O)/N=C/1\NC(=O)\C(=C\c2cc([N+](=O)[O-])c(cc2N3CCOCC3)N4CCOCC4)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C12 compound treatment 870729.0 287000.0 1.28 805660.0 243000.0 1.2 1.7597 0.9995 1973267 ChemDiv1_006392 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(Br)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C13 compound treatment 1229934.0 646000.0 2.89 1178494.0 616000.0 3.05 4.2027 0.9996 1973268 ChemDiv1_006393 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C14 compound treatment 734988.0 151000.0 0.68 671252.0 109000.0 0.54 0.8593 0.9935 1736578 ChemDiv1_006394 Clc1c(sc2ccccc12)C(=O)Nc3cccc(c3)c4nc5ncccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C15 compound treatment 796653.0 213000.0 0.95 751463.0 189000.0 0.94 1.3354 1.0 1973269 ChemDiv1_006395 CCOc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C16 compound treatment 696171.0 112000.0 0.5 670160.0 108000.0 0.53 0.7326 0.9996 1221744 ChemDiv1_006396 Clc1ccc(NC(=O)c2ccc3OCCOc3c2)nc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C17 compound treatment 767415.0 184000.0 0.82 733038.0 170000.0 0.84 1.1783 0.9999 1933192 ChemDiv1_006397 OC(=O)c1ccccc1c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C18 compound treatment 699808.0 116000.0 0.52 660173.0 97500.0 0.48 0.7091 0.9993 1973270 ChemDiv1_006398 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C19 compound treatment 702559.0 119000.0 0.53 657331.0 94700.0 0.47 0.7078 0.998 1933239 ChemDiv1_006399 Fc1ccc(cc1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C20 compound treatment 682781.0 99100.0 0.44 636620.0 74000.0 0.37 0.5727 0.9955 1524537 ChemDiv1_006400 Cc1ccc(C)c(NC(=O)CSc2nc3ccccc3o2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C21 compound treatment 768405.0 185000.0 0.83 738639.0 176000.0 0.87 1.2011 0.9996 1973271 ChemDiv1_006401 CC(=O)/N=C/1\NC(=O)\C(=C/c2ccc(OCc3ccccc3)cc2)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C22 compound treatment 664818.0 81100.0 0.36 625935.0 63300.0 0.31 0.4784 0.9973 1704070 ChemDiv1_006402 Clc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C23 mock treatment 683792.0 100000.0 0.45 619803.0 57200.0 0.28 0.517 0.9755 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 C24 mock treatment 508316.0 -75400.0 -0.34 504568.0 -58100.0 -0.29 -0.4421 -0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D01 compound treatment 614040.0 30300.0 0.14 565686.0 3050.0 0.02 0.1066 0.781 1973272 ChemDiv1_006403 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Br)cc3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D02 compound treatment 654725.0 71000.0 0.32 598220.0 35600.0 0.18 0.3494 0.9613 1621626 ChemDiv1_006404 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(Cl)cc4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D03 compound treatment 685999.0 102000.0 0.46 628893.0 66300.0 0.33 0.5558 0.9867 1281074 ChemDiv1_006405 COc1ccc2[nH]c(SCC(=O)Nc3cccc(NC(=O)CSc4nc5cc(OC)ccc5[nH]4)n3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D04 compound treatment 689890.0 106000.0 0.48 634213.0 71600.0 0.35 0.5868 0.9896 1195053 ChemDiv1_006406 Cc1cccc(NC(=O)CC2SC(=O)NC2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D05 compound treatment 753952.0 170000.0 0.76 726235.0 164000.0 0.81 1.1119 0.9995 1260335 ChemDiv1_006407 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC(=O)c3ccccc3Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D06 compound treatment 708336.0 125000.0 0.56 670682.0 108000.0 0.54 0.7729 0.9998 1520079 ChemDiv1_006408 COc1ccc(cc1Cn2nnc3ccccc23)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D07 compound treatment 707147.0 123000.0 0.55 678407.0 116000.0 0.57 0.7962 0.9998 1436118 ChemDiv1_006409 CCNc1nc(NCC)nc(Oc2ccccc2C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D08 compound treatment 705906.0 122000.0 0.55 677806.0 115000.0 0.57 0.7902 0.9998 1262884 ChemDiv1_006410 COc1ccc(cc1COc2ccc(F)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D09 compound treatment 701848.0 118000.0 0.53 694019.0 131000.0 0.65 0.8341 0.9947 1124802 ChemDiv1_006411 COc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D10 compound treatment 721979.0 138000.0 0.62 676125.0 113000.0 0.56 0.8352 0.9989 1531889 ChemDiv1_006412 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4cccc(C)c4C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D11 compound treatment 726262.0 143000.0 0.64 704277.0 142000.0 0.7 0.9473 0.9989 1232540 ChemDiv1_006413 COCc1cc(C)nc2sc(C(=O)c3ccc(Cl)cc3Cl)c(N)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D12 compound treatment 683283.0 99600.0 0.45 674702.0 112000.0 0.56 0.7077 0.9941 1973273 ChemDiv1_006414 COc1cc(ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D13 compound treatment 707515.0 124000.0 0.55 689091.0 126000.0 0.63 0.8348 0.9981 1973274 ChemDiv1_006415 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N4CCC(Cc5ccccc5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D14 compound treatment 655277.0 71600.0 0.32 685362.0 123000.0 0.61 0.6564 0.9552 1973275 ChemDiv1_006416 CCOC(=O)C(NC(=O)Cn1c2ccccc2c(=O)c3ccccc13)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D15 compound treatment 935502.0 352000.0 1.57 952702.0 390000.0 1.93 2.4798 0.9948 1973276 ChemDiv1_006417 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)Nc4nc(cs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D16 compound treatment 688594.0 105000.0 0.47 676860.0 114000.0 0.57 0.7321 0.9957 1973277 ChemDiv1_006418 Clc1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)ccc1Oc5ccc6ccccc6c5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D17 compound treatment 749815.0 166000.0 0.74 704354.0 142000.0 0.7 1.0221 0.9996 1973278 ChemDiv1_006419 CCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D18 compound treatment 677797.0 94100.0 0.42 661817.0 99200.0 0.49 0.6452 0.9971 1736638 ChemDiv1_006420 Cc1cc2nc(Cc3ccc(Cl)cc3Cl)c(=O)[nH]c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D19 compound treatment 735985.0 152000.0 0.68 678378.0 116000.0 0.57 0.8874 0.9963 1973279 ChemDiv1_006421 COCCN(CCOC)Cc1c(O)ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc12)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D20 compound treatment 716558.0 133000.0 0.59 663096.0 100000.0 0.5 0.7724 0.9961 1396891 ChemDiv1_006422 O=C(CSc1nc2ccccc2o1)N3CCc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D21 compound treatment 752253.0 169000.0 0.75 677340.0 115000.0 0.57 0.9352 0.9902 1313887 ChemDiv1_006423 O=C(Nc1nc(cs1)c2ccccc2)C3COc4ccccc4O3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D22 compound treatment 684981.0 101000.0 0.45 657344.0 94700.0 0.47 0.6523 0.9999 1973280 ChemDiv1_006424 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D23 mock treatment 688133.0 104000.0 0.47 638351.0 75700.0 0.38 0.5957 0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 D24 mock treatment 517808.0 -65900.0 -0.3 532486.0 -30100.0 -0.15 -0.3143 -0.9502 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E01 compound treatment 666425.0 82700.0 0.37 397576.0 -165000.0 -0.82 -0.3164 -0.3525 1925059 ChemDiv1_006425 COCCOC(=O)c1c(C)oc2ccc(OCc3cccc(Br)c3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E02 compound treatment 675935.0 92200.0 0.41 566509.0 3870.0 0.02 0.3054 0.7392 1552131 ChemDiv1_006426 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)ccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E03 compound treatment 718833.0 135000.0 0.6 650624.0 88000.0 0.44 0.7359 0.9871 1973281 ChemDiv1_006427 CC(C)OC(=O)c1nnn(c1CSc2nc3ccccc3o2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E04 compound treatment 712289.0 129000.0 0.58 626045.0 63400.0 0.31 0.6291 0.9594 1271571 ChemDiv1_006428 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2OC)C(=O)Nc3ccccc3C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E05 compound treatment 737487.0 154000.0 0.69 657497.0 94900.0 0.47 0.819 0.9827 1128436 ChemDiv1_006429 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E06 compound treatment 678860.0 95100.0 0.43 636464.0 73800.0 0.37 0.5597 0.9971 1581013 ChemDiv1_006430 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OC5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E07 compound treatment 745960.0 162000.0 0.73 678359.0 116000.0 0.57 0.9189 0.9931 1973282 ChemDiv1_006431 COc1cccc(OCCOc2ccc(cc2C=c3sc4nc5ccccc5n4c3=O)[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E08 compound treatment 709081.0 125000.0 0.56 670673.0 108000.0 0.54 0.7752 0.9997 1973283 ChemDiv1_006432 CCOC(=O)CSc1nc2ccc(NC(=O)CSc3nc4sc5CCCCc5c4c(=O)n3C)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E09 compound treatment 707946.0 124000.0 0.56 674145.0 112000.0 0.55 0.7838 1.0 1973284 ChemDiv1_006433 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3cccc4C(=O)c5ccccc5C(=O)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E10 compound treatment 4772484.0 4190000.0 18.75 4347736.0 3790000.0 18.75 26.5173 1.0 1677922 ChemDiv1_006434 COc1cc(C=c2sc3nc4c(C)cc(C)cc4n3c2=O)cc(Br)c1OCC#C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E11 compound treatment 751082.0 167000.0 0.75 690462.0 128000.0 0.63 0.9775 0.9965 1973285 ChemDiv1_006435 CC/N=C/1\S/C(=C\c2cc3OCOc3cc2Br)/C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E12 compound treatment 742498.0 159000.0 0.71 676931.0 114000.0 0.57 0.9029 0.9937 1973286 ChemDiv1_006436 COc1ccc(cc1[N+](=O)[O-])C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E13 compound treatment 759065.0 175000.0 0.78 669300.0 107000.0 0.53 0.9286 0.9815 1335771 ChemDiv1_006437 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(F)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E14 compound treatment 714161.0 130000.0 0.58 678631.0 116000.0 0.57 0.8192 1.0 1728772 ChemDiv1_006438 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)c4nc5ncccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E15 compound treatment 779562.0 196000.0 0.88 699534.0 137000.0 0.68 1.0994 0.992 1973287 ChemDiv1_006439 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\S\C(=N\C)\N(C)C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E16 compound treatment 719031.0 135000.0 0.61 649630.0 87000.0 0.43 0.733 0.9861 1927410 ChemDiv1_006440 [O-][N+](=O)c1cc(NC(=O)c2ccc3OCCOc3c2)ccc1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E17 compound treatment 775989.0 192000.0 0.86 704704.0 142000.0 0.7 1.1062 0.995 1973288 ChemDiv1_006441 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E18 compound treatment 724125.0 140000.0 0.63 674843.0 112000.0 0.56 0.8375 0.9981 1973289 ChemDiv1_006442 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Br)c1OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E19 compound treatment 773401.0 190000.0 0.85 682950.0 120000.0 0.6 1.0218 0.985 1706513 ChemDiv1_006443 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E20 compound treatment 725268.0 142000.0 0.63 658295.0 95700.0 0.47 0.7831 0.9898 1433732 ChemDiv1_006444 CC(=O)Nc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E21 compound treatment 743672.0 160000.0 0.72 682766.0 120000.0 0.6 0.9271 0.9958 1973290 ChemDiv1_006445 Cc1cc(/C=C/2\NC(=O)NC2=O)c(C)n1c3ccc(cc3)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E22 compound treatment 730978.0 147000.0 0.66 644491.0 81900.0 0.41 0.7528 0.9728 1663539 ChemDiv1_006446 COc1ccc(Cl)cc1NC(=O)CSc2nc3cc(C)ccc3[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E23 mock treatment 690254.0 107000.0 0.48 650172.0 87500.0 0.43 0.6438 0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 E24 mock treatment 527069.0 -56700.0 -0.25 517385.0 -45300.0 -0.22 -0.3378 -0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F01 compound treatment 634510.0 50800.0 0.23 582337.0 19700.0 0.1 0.2298 0.9287 1123022 ChemDiv1_006447 COc1ccc2[nH]c(SCC(=O)Nc3ccccc3Br)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F02 compound treatment 620249.0 36500.0 0.16 602352.0 39700.0 0.2 0.2547 0.9958 1407862 ChemDiv1_006448 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccccc4F)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F03 compound treatment 671336.0 87600.0 0.39 626089.0 63500.0 0.31 0.4996 0.994 1973291 ChemDiv1_006449 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F04 compound treatment 675368.0 91600.0 0.41 645121.0 82500.0 0.41 0.579 1.0 1659856 ChemDiv1_006450 Cc1ccccc1NC(=O)CC2SC(=O)NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F05 compound treatment 690383.0 107000.0 0.48 641799.0 79200.0 0.39 0.6149 0.9952 1415095 ChemDiv1_006451 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F06 compound treatment 695043.0 111000.0 0.5 641202.0 78600.0 0.39 0.6276 0.9925 1973292 ChemDiv1_006452 COc1ccc(cc1Cn2nc(C)c([N+](=O)[O-])c2C)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F07 compound treatment 696387.0 113000.0 0.5 691521.0 129000.0 0.64 0.8081 0.9932 1157320 ChemDiv1_006453 CCOC(=O)c1ccc(Oc2nc(NC(C)C)nc(NC(C)C)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F08 compound treatment 723040.0 139000.0 0.62 672782.0 110000.0 0.55 0.8268 0.9978 1604717 ChemDiv1_006454 COc1ccc(cc1COc2ccc(Cl)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F09 compound treatment 741637.0 158000.0 0.71 694933.0 132000.0 0.66 0.9633 0.9993 1262179 ChemDiv1_006455 Cc1ccc(cc1S(=O)(=O)N)c2nnc(N3CCOCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F10 compound treatment 740646.0 157000.0 0.7 666955.0 104000.0 0.52 0.8621 0.9886 1693689 ChemDiv1_006456 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F11 compound treatment 721430.0 138000.0 0.62 684491.0 122000.0 0.6 0.8627 0.9999 1973293 ChemDiv1_006457 COc1ccc(/C=C(\C#N)/C(=O)Nc2ncc(Cc3cc(Cl)ccc3Cl)s2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F12 compound treatment 708008.0 124000.0 0.56 660761.0 98100.0 0.49 0.7371 0.9977 1973294 ChemDiv1_006458 Ic1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F13 compound treatment 716287.0 133000.0 0.59 682607.0 120000.0 0.59 0.8398 1.0 1973295 ChemDiv1_006459 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F14 compound treatment 714775.0 131000.0 0.59 680676.0 118000.0 0.58 0.8283 1.0 1973296 ChemDiv1_006460 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Oc5ccc(Cl)c(Cl)c5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F15 compound treatment 774388.0 191000.0 0.85 800460.0 238000.0 1.18 1.4366 0.9875 1973297 ChemDiv1_006461 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F16 compound treatment 677288.0 93600.0 0.42 694898.0 132000.0 0.66 0.7595 0.9766 1973298 ChemDiv1_006462 [O-][N+](=O)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F17 compound treatment 726754.0 143000.0 0.64 695143.0 133000.0 0.66 0.9169 0.9999 1973299 ChemDiv1_006463 CCC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F18 compound treatment 713977.0 130000.0 0.58 680542.0 118000.0 0.58 0.8253 1.0 1442755 ChemDiv1_006464 COc1ccc(OC)c(Cc2nc3cc(C)c(C)cc3[nH]c2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F19 compound treatment 694503.0 111000.0 0.5 709581.0 147000.0 0.73 0.8654 0.9825 1973300 ChemDiv1_006465 COc1ccc(cc1OC)c2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F20 compound treatment 712863.0 129000.0 0.58 665735.0 103000.0 0.51 0.7699 0.9981 1380420 ChemDiv1_006466 O=C(CSc1ncn[nH]1)N2c3ccccc3Sc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F21 compound treatment 4413391.0 3830000.0 17.14 5615204.0 5050000.0 25.03 29.8204 0.983 1973301 ChemDiv1_006467 COC(=O)CCCCCN1C(=O)/C(=C\c2cc(Br)c(O)c(OC)c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F22 compound treatment 666928.0 83200.0 0.37 632451.0 69800.0 0.35 0.5079 0.9993 1973302 ChemDiv1_006468 CCOc1cccc(c1)N2C(=O)/C(=C/c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F23 mock treatment 706370.0 123000.0 0.55 627266.0 64600.0 0.32 0.6146 0.967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 F24 mock treatment 507510.0 -76200.0 -0.34 505154.0 -57500.0 -0.28 -0.4426 -0.996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G01 compound treatment 636506.0 52800.0 0.24 558824.0 -3810.0 -0.02 0.1537 0.6485 1924644 ChemDiv1_006469 CCOC(=O)c1c(oc2cc(Br)c(OC(C)C(=O)OC)cc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G02 compound treatment 678545.0 94800.0 0.42 565980.0 3340.0 0.02 0.3118 0.7342 1407057 ChemDiv1_006470 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)c(OC)c2)C(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G03 compound treatment 721521.0 138000.0 0.62 641487.0 78900.0 0.39 0.7124 0.9757 1231067 ChemDiv1_006471 O=C(CSc1nc2ccccc2[nH]1)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G04 compound treatment 716091.0 132000.0 0.59 642500.0 79900.0 0.4 0.6987 0.9807 1421622 ChemDiv1_006472 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(C)cc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G05 compound treatment 727029.0 143000.0 0.64 655174.0 92500.0 0.46 0.7777 0.9864 1942267 ChemDiv1_006473 CC/1=NN(C(=O)\C1=C\c2ccc(OS(=O)(=O)c3ccccc3[N+](=O)[O-])cc2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G06 compound treatment 765680.0 182000.0 0.81 695188.0 133000.0 0.66 1.0403 0.9943 1930586 ChemDiv1_006474 Brc1cc(/C=C\2/NC(=S)NC2=O)ccc1OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G07 compound treatment 671901.0 88200.0 0.39 668623.0 106000.0 0.53 0.6504 0.9901 1973303 ChemDiv1_006475 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCCOc5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G08 compound treatment 729259.0 146000.0 0.65 645518.0 82900.0 0.41 0.751 0.9752 1521979 ChemDiv1_006476 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NCc6ccco6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G09 compound treatment 732076.0 148000.0 0.66 683390.0 121000.0 0.6 0.8926 0.9986 1214543 ChemDiv1_006477 Cc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2c1C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G10 compound treatment 665951.0 82200.0 0.37 684558.0 122000.0 0.6 0.6873 0.9718 1973304 ChemDiv1_006478 CC/N=C/1\S/C(=C\c2ccc(o2)c3ccc(Cl)c(c3)[N+](=O)[O-])/C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G11 compound treatment 1399146.0 815000.0 3.65 1241456.0 679000.0 3.36 4.9589 0.9992 1973305 ChemDiv1_006479 COc1cc(c2ccc(/C=C/3\S\C(=N\C(=O)C)\NC3=O)o2)c(OC)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G12 compound treatment 1421011.0 837000.0 3.75 1334714.0 772000.0 3.82 5.3547 0.9999 1973306 ChemDiv1_006480 CCOC(=O)Cn1cc(/C=C/2\Sc3ccccc3C2=O)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G13 compound treatment 735413.0 152000.0 0.68 677502.0 115000.0 0.57 0.8825 0.9961 1973307 ChemDiv1_006481 Cc1ccsc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G14 compound treatment 763347.0 180000.0 0.8 675297.0 113000.0 0.56 0.9632 0.9841 1973308 ChemDiv1_006482 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G15 compound treatment 810383.0 227000.0 1.01 741705.0 179000.0 0.89 1.3447 0.9978 1973309 ChemDiv1_006483 COc1cccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G16 compound treatment 717304.0 134000.0 0.6 703635.0 141000.0 0.7 0.9167 0.997 1516302 ChemDiv1_006484 CCCOC(=O)c1ccc(NC(=O)c2ccc3OCCOc3c2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G17 compound treatment 777270.0 194000.0 0.87 752459.0 190000.0 0.94 1.2776 0.9992 1933241 ChemDiv1_006485 COc1ccc(OC)c(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G18 compound treatment 742950.0 159000.0 0.71 700773.0 138000.0 0.68 0.9879 0.9998 1973310 ChemDiv1_006486 CCCOc1c(Br)cc(C=C2C(=O)NC(=O)NC2=O)cc1OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G19 compound treatment 1104546.0 521000.0 2.33 989600.0 427000.0 2.12 3.1441 0.9988 1973311 ChemDiv1_006487 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)ccc1OCc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G20 compound treatment 732871.0 149000.0 0.67 654117.0 91500.0 0.45 0.7925 0.9822 1400839 ChemDiv1_006488 NC(=O)c1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G21 compound treatment 744723.0 161000.0 0.72 671700.0 109000.0 0.54 0.8916 0.9899 1973312 ChemDiv1_006489 COc1ccc2[nH]c-3c(CCn4c3nc5sc6CCCCc6c5c4=N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G22 compound treatment 712310.0 129000.0 0.58 669640.0 107000.0 0.53 0.7818 0.9992 1731654 ChemDiv1_006490 Cc1ccc2[nH]c(SCC(=O)Nc3cccc(Cl)c3C)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G23 mock treatment 711040.0 127000.0 0.57 651480.0 88800.0 0.44 0.7142 0.9918 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 G24 mock treatment 531555.0 -52200.0 -0.23 529484.0 -33200.0 -0.16 -0.2813 -0.9852 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H01 compound treatment 614466.0 30700.0 0.14 570222.0 7590.0 0.04 0.1239 0.8684 1347885 ChemDiv1_006491 CCOc1ccc2nc(SCC(=O)Nc3ccc(NC(=O)C)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H02 compound treatment 623826.0 40100.0 0.18 560799.0 -1840.0 -0.01 0.1205 0.6704 1642811 ChemDiv1_006492 COc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H03 compound treatment 664547.0 80800.0 0.36 625177.0 62500.0 0.31 0.4749 0.997 1973313 ChemDiv1_006493 COC(=O)C1=C(C)OC(=C(C#N)C1C2CCCCC2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H04 compound treatment 683865.0 100000.0 0.45 636998.0 74400.0 0.37 0.5775 0.9952 1724260 ChemDiv1_006494 Oc1cccc(NC(=O)CC2SC(=O)N(C2=O)c3ccccc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H05 compound treatment 716213.0 132000.0 0.59 658416.0 95800.0 0.47 0.7549 0.9939 1973314 ChemDiv1_006495 COc1ccc(OC)c(c1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H06 compound treatment 710972.0 127000.0 0.57 645993.0 83400.0 0.41 0.6948 0.9875 1579110 ChemDiv1_006496 COc1ccc(cc1Cn2nnc3ccccc23)C4Nc5ccccc5C(=O)N4c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H07 compound treatment 706686.0 123000.0 0.55 681359.0 119000.0 0.59 0.8051 0.9995 1221521 ChemDiv1_006497 CCNc1nc(NCC)nc(Oc2ccc(cc2)C(=O)OCC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H08 compound treatment 717017.0 133000.0 0.6 696101.0 133000.0 0.66 0.8894 0.9987 1932107 ChemDiv1_006498 COc1ccc(cc1COc2ccc([N+](=O)[O-])c(C)c2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H09 compound treatment 720820.0 137000.0 0.61 675170.0 113000.0 0.56 0.8281 0.9989 1717075 ChemDiv1_006499 CNS(=O)(=O)c1cc(ccc1C)c2nnc(N3CCOCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H10 compound treatment 739590.0 156000.0 0.7 681661.0 119000.0 0.59 0.9103 0.9965 1518824 ChemDiv1_006500 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)ccc4O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H11 compound treatment 1264629.0 681000.0 3.05 997498.0 435000.0 2.15 3.6785 0.9856 1973315 ChemDiv1_006501 CCOC(=O)CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H12 compound treatment 681036.0 97300.0 0.44 677245.0 115000.0 0.57 0.7095 0.9914 1973316 ChemDiv1_006502 Clc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c(c1)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H13 compound treatment 728675.0 145000.0 0.65 664571.0 102000.0 0.5 0.8159 0.9923 1973317 ChemDiv1_006503 Cc1cc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H14 compound treatment 695109.0 111000.0 0.5 685424.0 123000.0 0.61 0.7827 0.9951 1973318 ChemDiv1_006504 Cn1nc(cc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H15 compound treatment 712294.0 129000.0 0.58 740822.0 178000.0 0.88 1.0311 0.9785 1973319 ChemDiv1_006505 CCN(Cc1ccccc1)C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H16 compound treatment 725563.0 142000.0 0.63 677630.0 115000.0 0.57 0.8518 0.9985 1305448 ChemDiv1_006506 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H17 compound treatment 740902.0 157000.0 0.7 703050.0 140000.0 0.7 0.9894 1.0 1973320 ChemDiv1_006507 CCCC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H18 compound treatment 697621.0 114000.0 0.51 665175.0 103000.0 0.51 0.7197 1.0 1973321 ChemDiv1_006508 Cc1ccc2n(CC(=O)Nc3ccc(F)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H19 compound treatment 693833.0 110000.0 0.49 683032.0 120000.0 0.6 0.7703 0.9955 1973322 ChemDiv1_006509 COc1ccc(cc1OC)c2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H20 compound treatment 708372.0 125000.0 0.56 679477.0 117000.0 0.58 0.8038 0.9998 1368893 ChemDiv1_006510 Cc1ccc(C#N)c(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H21 compound treatment 740942.0 157000.0 0.7 665534.0 103000.0 0.51 0.8581 0.9875 1726934 ChemDiv1_006511 Cc1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H22 compound treatment 696730.0 113000.0 0.51 655015.0 92400.0 0.46 0.6813 0.9987 1973323 ChemDiv1_006512 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\c3ccc4OCOc4c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H23 mock treatment 693116.0 109000.0 0.49 653905.0 91300.0 0.45 0.666 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 H24 mock treatment 286993.0 -297000.0 -1.33 493900.0 -68700.0 -0.34 -1.18 -0.8605 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I01 compound treatment 649782.0 66100.0 0.3 558662.0 -3970.0 -0.02 0.1952 0.6586 1973324 ChemDiv1_006513 CCOC(=O)c1c(oc2cc(Br)c(OCC(=O)OC)cc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I02 compound treatment 673878.0 90200.0 0.4 579782.0 17100.0 0.08 0.3454 0.8376 1973325 ChemDiv1_006514 CC(C)OCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I03 compound treatment 714039.0 130000.0 0.58 628316.0 65700.0 0.33 0.6426 0.962 1468591 ChemDiv1_006515 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OC(=O)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I04 compound treatment 714875.0 131000.0 0.59 624865.0 62200.0 0.31 0.6331 0.9548 1394260 ChemDiv1_006516 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I05 compound treatment 730121.0 146000.0 0.66 651524.0 88900.0 0.44 0.7748 0.9813 1973326 ChemDiv1_006517 CC/1=NN(C(=O)\C1=C/c2ccccc2OS(=O)(=O)c3ccccc3[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I06 compound treatment 719111.0 135000.0 0.61 625683.0 63000.0 0.31 0.6494 0.9525 1973327 ChemDiv1_006518 [O-][N+](=O)c1cccc(c1)n2ccc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccccc4)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I07 compound treatment 735082.0 151000.0 0.68 658524.0 95900.0 0.48 0.815 0.9849 1973328 ChemDiv1_006519 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCCOc5ccccc5C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I08 compound treatment 707557.0 124000.0 0.55 666297.0 104000.0 0.51 0.7551 0.9993 1973329 ChemDiv1_006520 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NC6CC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I09 compound treatment 749850.0 166000.0 0.74 664301.0 102000.0 0.5 0.882 0.982 1973330 ChemDiv1_006521 CC(=O)Nc1ccc(cc1)n2c(=O)c3ccc4c(=O)n(c5ccc(NC(=O)C)cc5)c(=O)c6ccc(c2=O)c3c46 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I10 compound treatment 1006457.0 423000.0 1.89 861191.0 299000.0 1.48 2.3839 0.9926 1973331 ChemDiv1_006522 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)c(Br)cc1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I11 compound treatment 762418.0 179000.0 0.8 684589.0 122000.0 0.6 0.9928 0.9904 1700914 ChemDiv1_006523 Cn1c(SCc2cc3OCOc3cc2Cl)nc4n(C)c(=O)n(C)c(=O)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I12 compound treatment 736946.0 153000.0 0.69 650936.0 88300.0 0.44 0.7943 0.9764 1298193 ChemDiv1_006524 Cn1ccnc1Sc2nc(Nc3cccc(Cl)c3)nc(n2)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I13 compound treatment 767293.0 184000.0 0.82 682645.0 120000.0 0.59 1.0014 0.9874 1973332 ChemDiv1_006525 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I14 compound treatment 758064.0 174000.0 0.78 675983.0 113000.0 0.56 0.9489 0.987 1930478 ChemDiv1_006526 [O-][N+](=O)c1cc(Cl)ccc1N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I15 compound treatment 748408.0 165000.0 0.74 687157.0 125000.0 0.62 0.9575 0.9961 1973333 ChemDiv1_006527 COc1ccc(OC)c(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I16 compound treatment 725334.0 142000.0 0.63 681089.0 118000.0 0.59 0.8632 0.9993 1973334 ChemDiv1_006528 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)c3ccc4OCCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I17 compound treatment 1159265.0 576000.0 2.58 1211755.0 649000.0 3.22 4.0955 0.994 1973335 ChemDiv1_006529 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Br)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I18 compound treatment 729248.0 146000.0 0.65 665180.0 103000.0 0.51 0.8198 0.9924 1973336 ChemDiv1_006530 CCCOc1c(Br)cc(C=C2C(=O)NC(=S)NC2=O)cc1OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I19 compound treatment 848669.0 265000.0 1.19 745327.0 183000.0 0.91 1.4786 0.9911 1973337 ChemDiv1_006531 Cc1ccsc1/C=C/2\Sc3ccccc3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I20 compound treatment 727539.0 144000.0 0.64 676182.0 114000.0 0.56 0.853 0.9977 1393164 ChemDiv1_006532 COc1ccc(Cl)cc1NC(=O)CSc2nc3ccccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I21 compound treatment 767550.0 184000.0 0.82 708643.0 146000.0 0.72 1.0933 0.9979 1136641 ChemDiv1_006533 COc1ccc2[nH]c-3c(CCn4c3nc5sc6CCCCCc6c5c4=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I22 compound treatment 705425.0 122000.0 0.54 663656.0 101000.0 0.5 0.7391 0.9991 1933798 ChemDiv1_006534 Cc1ccc2[nH]c(SCC(=O)Nc3ccc(Br)cc3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I23 mock treatment 709112.0 125000.0 0.56 644229.0 81600.0 0.4 0.6827 0.987 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 I24 mock treatment 538735.0 -45000.0 -0.2 519184.0 -43500.0 -0.22 -0.2946 -0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J01 compound treatment 588992.0 5270.0 0.02 569791.0 7160.0 0.04 0.0417 0.9804 1396822 ChemDiv1_006535 CCOc1ccc2nc(SCC(=O)Nc3cc(Cl)ccc3OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J02 compound treatment 644892.0 61200.0 0.27 583630.0 21000.0 0.1 0.2672 0.9121 1723896 ChemDiv1_006536 CCOc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J03 compound treatment 719627.0 136000.0 0.61 658911.0 96300.0 0.48 0.7674 0.9927 1973338 ChemDiv1_006537 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J04 compound treatment 676998.0 93300.0 0.42 614579.0 51900.0 0.26 0.4772 0.973 1973339 ChemDiv1_006538 COC(=O)CC1SC(=O)N(CNc2ccc(cc2)[N+](=O)[O-])C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J05 compound treatment 701135.0 117000.0 0.53 640478.0 77800.0 0.39 0.6443 0.9884 1642304 ChemDiv1_006539 COc1ccc(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J06 compound treatment 718619.0 135000.0 0.6 633797.0 71200.0 0.35 0.6762 0.9672 1463088 ChemDiv1_006540 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J07 compound treatment 689953.0 106000.0 0.48 645734.0 83100.0 0.41 0.6273 0.9974 1632265 ChemDiv1_006541 CCNc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OCC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J08 compound treatment 690177.0 106000.0 0.48 650997.0 88400.0 0.44 0.6465 0.9991 1926605 ChemDiv1_006542 COc1ccc(cc1COc2ccc(cc2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J09 compound treatment 736986.0 153000.0 0.69 726979.0 164000.0 0.81 1.0608 0.9964 1973340 ChemDiv1_006543 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3F)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J10 compound treatment 646115.0 62400.0 0.28 668693.0 106000.0 0.53 0.569 0.9563 1973341 ChemDiv1_006544 COc1ccc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J11 compound treatment 1151530.0 568000.0 2.54 1062262.0 500000.0 2.48 3.5474 0.9999 1973342 ChemDiv1_006545 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J12 compound treatment 634689.0 51000.0 0.23 679913.0 117000.0 0.58 0.5721 0.9166 1973343 ChemDiv1_006546 FC(F)(F)Oc1cccc(CNC(=O)Cn2c3ccccc3c(=O)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J13 compound treatment 758123.0 174000.0 0.78 666467.0 104000.0 0.51 0.9157 0.9795 1973344 ChemDiv1_006547 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)NC4=NCCS4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J14 compound treatment 689756.0 106000.0 0.47 669854.0 107000.0 0.53 0.7112 0.9984 1973345 ChemDiv1_006548 FC(F)(F)Oc1cc(Br)ccc1NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J15 compound treatment 780212.0 196000.0 0.88 743236.0 181000.0 0.89 1.2546 1.0 1973346 ChemDiv1_006549 O=C(CCN1C(=O)/C(=C/c2ccc3OCOc3c2)/SC1=S)N(CCC#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J16 compound treatment 720083.0 136000.0 0.61 664012.0 101000.0 0.5 0.7867 0.9953 1524818 ChemDiv1_006550 COc1cccc(CNn2c(nc3ccccc3c2=O)c4cc(OC)c(OC)c(OC)c4)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J17 compound treatment 723045.0 139000.0 0.62 718106.0 155000.0 0.77 0.9856 0.9945 1973347 ChemDiv1_006551 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)C(C)C)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J18 compound treatment 718908.0 135000.0 0.61 669319.0 107000.0 0.53 0.8016 0.9977 1154272 ChemDiv1_006552 Cc1cc2nc(Cc3ccc4OCOc4c3)c(=O)[nH]c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J19 compound treatment 699645.0 116000.0 0.52 667527.0 105000.0 0.52 0.7343 1.0 1973348 ChemDiv1_006553 COc1ccc(cc1OC)c2c(oc3c(CN4CCOCC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J20 compound treatment 710548.0 127000.0 0.57 656280.0 93600.0 0.46 0.7295 0.995 1241593 ChemDiv1_006554 Cc1ccc2c(N)c(sc2n1)C(=O)N3c4ccccc4Sc5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J21 compound treatment 748170.0 164000.0 0.74 687240.0 125000.0 0.62 0.957 0.9962 1304536 ChemDiv1_006555 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Cl)c(c3)c4nc5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J22 compound treatment 785746.0 202000.0 0.9 741580.0 179000.0 0.89 1.2663 1.0 1973349 ChemDiv1_006556 CCOc1ccc(OCC)c(c1)N2C(=O)NC(=O)/C(=C\C=C\c3ccco3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J23 mock treatment 682718.0 99000.0 0.44 644233.0 81600.0 0.4 0.5992 0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 J24 mock treatment 529199.0 -54500.0 -0.24 489618.0 -73000.0 -0.36 -0.4284 -0.9817 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K01 compound treatment 649879.0 66200.0 0.3 558378.0 -4260.0 -0.02 0.1945 0.6551 1256632 ChemDiv1_006557 Cc1ccc(cc1)C(=O)c2oc3ccc(Cl)cc3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K02 compound treatment 649328.0 65600.0 0.29 575948.0 13300.0 0.07 0.2543 0.8449 1580005 ChemDiv1_006558 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Cl)c(O)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K03 compound treatment 721472.0 138000.0 0.62 623262.0 60600.0 0.3 0.6484 0.9453 1973350 ChemDiv1_006559 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K04 compound treatment 696523.0 113000.0 0.5 620692.0 58100.0 0.29 0.5604 0.9644 1566250 ChemDiv1_006560 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(Br)c(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K05 compound treatment 1002806.0 419000.0 1.88 1012222.0 450000.0 2.23 2.9014 0.9964 1973351 ChemDiv1_006561 CCOc1cc(/C=C\2/SC(=S)NC2=O)ccc1OS(=O)(=O)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K06 compound treatment 723094.0 139000.0 0.62 620301.0 57700.0 0.29 0.6431 0.9373 1973352 ChemDiv1_006562 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)c(cc1OC)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K07 compound treatment 716478.0 133000.0 0.59 624756.0 62100.0 0.31 0.6378 0.9531 1973353 ChemDiv1_006563 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K08 compound treatment 731910.0 148000.0 0.66 663204.0 101000.0 0.5 0.8213 0.99 1535493 ChemDiv1_006564 CCSc1nc2ccc(NC(=O)c3ccccc3C(=O)N4CCCCC4)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K09 compound treatment 761383.0 178000.0 0.8 696262.0 134000.0 0.66 1.0304 0.9958 1635171 ChemDiv1_006565 CCOC(=O)c1c(C)oc2c(Cl)cc(NS(=O)(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K10 compound treatment 768730.0 185000.0 0.83 654668.0 92000.0 0.46 0.908 0.9605 1973354 ChemDiv1_006566 CC/1=NN(C(=O)\C1=C/c2cnn(c2)c3ccc(C)c(C)c3)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K11 compound treatment 758862.0 175000.0 0.78 678450.0 116000.0 0.57 0.96 0.9882 1159821 ChemDiv1_006567 CN(C)C(=O)Oc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K12 compound treatment 720863.0 137000.0 0.61 660047.0 97400.0 0.48 0.7753 0.9929 1319539 ChemDiv1_006568 C1CN(CCO1)c2nc(nc(n2)n3cccn3)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K13 compound treatment 785228.0 202000.0 0.9 696146.0 134000.0 0.66 1.1055 0.9884 1973355 ChemDiv1_006569 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K14 compound treatment 726908.0 143000.0 0.64 662954.0 100000.0 0.5 0.8046 0.9921 1936006 ChemDiv1_006570 Cc1c(Cl)cccc1c2ccc(o2)C(=O)Nc3ccc4C(=O)c5ccccc5C(=O)c4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K15 compound treatment 835456.0 252000.0 1.13 787169.0 225000.0 1.11 1.5833 1.0 1973356 ChemDiv1_006571 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\S\C(=N\C(=O)C)\NC3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K16 compound treatment 721348.0 138000.0 0.62 651912.0 89300.0 0.44 0.7483 0.9868 1667149 ChemDiv1_006572 COC(=O)c1cc(NC(=O)c2ccc3OCCOc3c2)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K17 compound treatment 1454058.0 870000.0 3.9 1163376.0 601000.0 2.98 4.8592 0.9912 1973357 ChemDiv1_006573 COc1cc(C=c2sc3nc4c(Br)c(C)c(C)cc4n3c2=O)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K18 compound treatment 698834.0 115000.0 0.52 638690.0 76100.0 0.38 0.6308 0.9882 1973358 ChemDiv1_006574 CCCOc1c(Br)cc(/C=C/2\NC(=S)NC2=O)cc1OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K19 compound treatment 1429559.0 846000.0 3.79 1110127.0 547000.0 2.71 4.5951 0.9866 1418681 ChemDiv1_006575 COc1cc(OC)c(cc1OC)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K20 compound treatment 718961.0 135000.0 0.61 656155.0 93500.0 0.46 0.7556 0.9913 1973359 ChemDiv1_006576 Brc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K21 compound treatment 769969.0 186000.0 0.83 702396.0 140000.0 0.69 1.0791 0.9957 1297726 ChemDiv1_006577 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)c(OC)c2)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K22 compound treatment 705823.0 122000.0 0.55 637950.0 75300.0 0.37 0.6503 0.9827 1376487 ChemDiv1_006578 Cc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K23 mock treatment 712584.0 129000.0 0.58 663862.0 101000.0 0.5 0.7625 0.9976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 K24 mock treatment 524644.0 -59100.0 -0.26 502118.0 -60500.0 -0.3 -0.399 -0.998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L01 compound treatment 623182.0 39500.0 0.18 554447.0 -8190.0 -0.04 0.0962 0.5309 1658171 ChemDiv1_006579 CCOc1ccc2nc(SCC(=O)Nc3cccc(SC)c3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L02 compound treatment 651988.0 68300.0 0.31 564315.0 1680.0 0.01 0.222 0.7261 1419149 ChemDiv1_006580 Cc1c(NC(=O)CC2SC(=O)NC2=O)c(=O)n(c3ccccc3)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L03 compound treatment 684127.0 100000.0 0.45 661186.0 98600.0 0.49 0.663 0.9991 1162869 ChemDiv1_006581 COC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccc(F)cc3)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L04 compound treatment 689613.0 106000.0 0.47 625781.0 63100.0 0.31 0.5564 0.9797 1718793 ChemDiv1_006582 O=C(CC1SC(=O)NC1=O)Nc2ccc(NC(=O)CC3SC(=O)NC3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L05 compound treatment 701267.0 118000.0 0.53 602796.0 40200.0 0.2 0.5127 0.9115 1252646 ChemDiv1_006583 CCOc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L06 compound treatment 703378.0 120000.0 0.54 620525.0 57900.0 0.29 0.5815 0.9571 1278265 ChemDiv1_006584 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L07 compound treatment 730878.0 147000.0 0.66 649927.0 87300.0 0.43 0.7716 0.9792 1740380 ChemDiv1_006585 Cc1nnc(Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L08 compound treatment 691972.0 108000.0 0.48 632579.0 69900.0 0.35 0.5876 0.9865 1394819 ChemDiv1_006586 COc1ccc(cc1COc2cccc(C)c2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L09 compound treatment 690487.0 107000.0 0.48 673948.0 111000.0 0.55 0.7278 0.9975 1973360 ChemDiv1_006587 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L10 compound treatment 717267.0 134000.0 0.6 658790.0 96200.0 0.48 0.7595 0.9937 1259021 ChemDiv1_006588 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)ccc4O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L11 compound treatment 708559.0 125000.0 0.56 662772.0 100000.0 0.5 0.7459 0.9982 1973361 ChemDiv1_006589 Oc1ccc(cc1NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L12 compound treatment 704575.0 121000.0 0.54 657229.0 94600.0 0.47 0.7139 0.9974 1973362 ChemDiv1_006590 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)cc(Sc5ccc(F)cc5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L13 compound treatment 711276.0 128000.0 0.57 652742.0 90100.0 0.45 0.7194 0.9926 1973363 ChemDiv1_006591 Cc1csc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L14 compound treatment 674343.0 90600.0 0.41 626167.0 63500.0 0.31 0.5094 0.9921 1973364 ChemDiv1_006592 CCSc1nnc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L15 compound treatment 875223.0 291000.0 1.3 815707.0 253000.0 1.25 1.8091 0.9998 1973365 ChemDiv1_006593 OC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L16 compound treatment 685668.0 102000.0 0.46 650549.0 87900.0 0.44 0.6306 0.9997 1973366 ChemDiv1_006594 [O-][N+](=O)c1cc(Nc2ncnc3ccccc23)cc(Oc4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L17 compound treatment 715639.0 132000.0 0.59 688830.0 126000.0 0.63 0.8596 0.9996 1973367 ChemDiv1_006595 CCOC(=O)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L18 compound treatment 674263.0 90500.0 0.41 638951.0 76300.0 0.38 0.5539 0.9994 1275470 ChemDiv1_006596 Cc1cc2nc(Cc3cc4OCOc4cc3Br)c(=O)[nH]c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L19 compound treatment 712032.0 128000.0 0.57 656324.0 93700.0 0.46 0.7343 0.9944 1973368 ChemDiv1_006597 COc1ccc(cc1OC)c2c(oc3c(CN4CCC(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L20 compound treatment 959991.0 376000.0 1.68 866528.0 304000.0 1.51 2.2555 0.9984 1973369 ChemDiv1_006598 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccc2C#N)c1C#N)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L21 compound treatment 766063.0 182000.0 0.82 706190.0 144000.0 0.71 1.08 0.9976 1973370 ChemDiv1_006599 Clc1c(sc2ccccc12)C(=O)Nc3cccc(NC(=O)c4cccc(Cl)c4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L22 compound treatment 709701.0 126000.0 0.56 648825.0 86200.0 0.43 0.7007 0.9906 1973371 ChemDiv1_006600 Cc1cc(Br)ccc1N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L23 mock treatment 679214.0 95500.0 0.43 649629.0 87000.0 0.43 0.607 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 L24 mock treatment 497397.0 -86300.0 -0.39 523920.0 -38700.0 -0.19 -0.4089 -0.9477 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M01 compound treatment 653086.0 69400.0 0.31 566164.0 3530.0 0.02 0.2319 0.7457 1421506 ChemDiv1_006601 Nc1c(oc2ccc(Cl)cc12)C(=O)c3ccc(Br)s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M02 compound treatment 668642.0 84900.0 0.38 584322.0 21700.0 0.11 0.3448 0.8728 1973372 ChemDiv1_006602 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M03 compound treatment 732849.0 149000.0 0.67 644496.0 81900.0 0.41 0.7588 0.9715 1973373 ChemDiv1_006603 COc1cccc(OCCOc2ccc(/C=C/3\C(=NN(C3=O)c4ccccc4)C)cc2OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M04 compound treatment 687725.0 104000.0 0.47 621792.0 59200.0 0.29 0.5364 0.9751 1436560 ChemDiv1_006604 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5coc6ccc(Cl)cc6c5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M05 compound treatment 738780.0 155000.0 0.69 655928.0 93300.0 0.46 0.8176 0.9805 1973374 ChemDiv1_006605 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCCOc5ccc(C)c(C)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M06 compound treatment 727417.0 144000.0 0.64 658690.0 96100.0 0.48 0.7913 0.989 1973375 ChemDiv1_006606 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(C)n(c3C)c4ccccc4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M07 compound treatment 767586.0 184000.0 0.82 665731.0 103000.0 0.51 0.9431 0.9737 1973376 ChemDiv1_006607 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OS(=O)(=O)c4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M08 compound treatment 654611.0 70900.0 0.32 618416.0 55800.0 0.28 0.4198 0.9976 1535909 ChemDiv1_006608 CC1CN(CC(C)O1)C(=O)c2ccccc2C(=O)Nc3ccc4nc(SCC(=O)NC5CCCCC5)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M09 compound treatment 751843.0 168000.0 0.75 664873.0 102000.0 0.51 0.8903 0.9814 1608336 ChemDiv1_006609 CCOC(=O)c1c(C)oc2c(Br)cc(NS(=O)(=O)c3ccc(OCC)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M10 compound treatment 731987.0 148000.0 0.66 665134.0 102000.0 0.51 0.8283 0.9913 1973377 ChemDiv1_006610 CC/N=C/1\S/C(=C\c2ccc(Oc3ccc(cc3C#N)[N+](=O)[O-])c(OC)c2)/C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M11 compound treatment 740675.0 157000.0 0.7 691283.0 129000.0 0.64 0.9474 0.9988 1683305 ChemDiv1_006611 CC(Sc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3cc4OCOc4cc3Cl)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M12 compound treatment 743781.0 160000.0 0.72 700691.0 138000.0 0.68 0.9902 0.9997 1973378 ChemDiv1_006612 Fc1ccc(/C=C/2\Sc3ccccc3C2=O)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M13 compound treatment 768797.0 185000.0 0.83 682477.0 120000.0 0.59 1.0056 0.9866 1973379 ChemDiv1_006613 Brc1cc2OCOc2cc1/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M14 compound treatment 743494.0 160000.0 0.72 686351.0 124000.0 0.61 0.9391 0.997 1250123 ChemDiv1_006614 COc1ccc(cc1OC)c2nc3cc(NC(=O)c4sc5ccccc5c4Cl)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M15 compound treatment 787080.0 203000.0 0.91 711082.0 148000.0 0.74 1.1637 0.9944 1558251 ChemDiv1_006615 CC1CCCN(C1)c2nc3nonc3nc2N4CCCC(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M16 compound treatment 721699.0 138000.0 0.62 660652.0 98000.0 0.49 0.7801 0.9929 1646831 ChemDiv1_006616 CSc1ncnc2ncn(CC(=O)Nc3ccc(C)c(C)c3)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M17 compound treatment 1562065.0 978000.0 4.38 1416364.0 854000.0 4.23 6.0872 0.9998 1949593 ChemDiv1_006617 COc1cc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M18 compound treatment 737171.0 153000.0 0.69 657595.0 95000.0 0.47 0.8183 0.983 1973380 ChemDiv1_006618 CCCOc1c(Br)cc(Br)cc1/C=C/2\NC(=S)NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M19 compound treatment 1812154.0 1230000.0 5.5 1750379.0 1190000.0 5.88 8.0488 0.9994 1467041 ChemDiv1_006619 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)c(Br)cc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M20 compound treatment 700798.0 117000.0 0.52 648133.0 85500.0 0.42 0.6701 0.9944 1244793 ChemDiv1_006620 Clc1ccccc1NC(=O)CSc2nc3ccccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M21 compound treatment 741557.0 158000.0 0.71 679281.0 117000.0 0.58 0.9082 0.995 1738272 ChemDiv1_006621 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2Cl)C(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M22 compound treatment 704241.0 121000.0 0.54 648132.0 85500.0 0.42 0.681 0.9928 1665628 ChemDiv1_006622 COc1ccc2[nH]c(SCC(=O)Nc3ccc(NC(=O)C)cc3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M23 mock treatment 706541.0 123000.0 0.55 658452.0 95800.0 0.47 0.7244 0.9973 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 M24 mock treatment 435808.0 -148000.0 -0.66 425863.0 -137000.0 -0.68 -0.9473 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N01 compound treatment 641880.0 58200.0 0.26 557445.0 -5190.0 -0.03 0.1659 0.6342 1588898 ChemDiv1_006623 OC(=O)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)cc(NC(=O)CSc4nc5ccccc5[nH]4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N02 compound treatment 626834.0 43100.0 0.19 571737.0 9100.0 0.05 0.1683 0.8494 1639393 ChemDiv1_006624 Cc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N03 compound treatment 692737.0 109000.0 0.49 611204.0 48600.0 0.24 0.5152 0.9469 1331567 ChemDiv1_006625 COC(=O)C1=C(C)OC(=C(C#N)C1c2cc(OC)ccc2OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N04 compound treatment 675860.0 92100.0 0.41 596258.0 33600.0 0.17 0.4094 0.9204 1401807 ChemDiv1_006626 CCOC(=O)c1[nH]c2c(OC)cc(OC)cc2c1CCN3C(=O)c4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N05 compound treatment 655701.0 72000.0 0.32 621116.0 58500.0 0.29 0.4327 0.9986 1973381 ChemDiv1_006627 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5ccccc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N06 compound treatment 679295.0 95600.0 0.43 604821.0 42200.0 0.21 0.4503 0.9457 1315230 ChemDiv1_006628 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N07 compound treatment 695920.0 112000.0 0.5 627013.0 64400.0 0.32 0.5806 0.976 1231439 ChemDiv1_006629 O=S(=O)(Nc1nccs1)c2ccc(Nc3nnc(c4ccccc4)c5ccccc35)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N08 compound treatment 712552.0 129000.0 0.58 637984.0 75300.0 0.37 0.6717 0.9778 1317640 ChemDiv1_006630 COc1ccc(cc1COc2c(C)cccc2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N09 compound treatment 723604.0 140000.0 0.63 665368.0 103000.0 0.51 0.8026 0.9947 1973382 ChemDiv1_006631 COCc1cc(C)nc(SCC(=O)Nc2ccc(C)c(C)c2)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N10 compound treatment 657362.0 73600.0 0.33 624251.0 61600.0 0.31 0.4489 0.9993 1973383 ChemDiv1_006632 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4cccc([N+](=O)[O-])c4O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N11 compound treatment 722407.0 139000.0 0.62 644668.0 82000.0 0.41 0.7263 0.9789 1973384 ChemDiv1_006633 Oc1cc(ccc1NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N12 compound treatment 651256.0 67500.0 0.3 619143.0 56500.0 0.28 0.4117 0.9993 1973385 ChemDiv1_006634 Fc1ccc(cc1CNC(=O)Cn2c3ccccc3c(=O)c4ccccc24)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N13 compound treatment 653103.0 69400.0 0.31 655557.0 92900.0 0.46 0.5451 0.9816 1973386 ChemDiv1_006635 CCc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N14 compound treatment 733685.0 150000.0 0.67 640627.0 78000.0 0.39 0.7479 0.9656 1973387 ChemDiv1_006636 O=C(Cn1c2ccccc2c(=O)c3ccccc13)Nc4ccc(Oc5ccc6C(=O)N(Cc7ccco7)C(=O)c6c5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N15 compound treatment 910378.0 327000.0 1.46 902890.0 340000.0 1.69 2.2258 0.9975 1973388 ChemDiv1_006637 OC(=O)c1cc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N16 compound treatment 724615.0 141000.0 0.63 645687.0 83100.0 0.41 0.7369 0.9786 1429793 ChemDiv1_006638 COc1ccc(cc1OC)c2nc3ccccc3c(=O)n2NCc4cc(Br)cs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N17 compound treatment 707817.0 124000.0 0.56 667615.0 105000.0 0.52 0.7605 0.9995 1973389 ChemDiv1_006639 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)c4cccnc4)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N18 compound treatment 710647.0 127000.0 0.57 657031.0 94400.0 0.47 0.7324 0.9953 1120541 ChemDiv1_006640 Brc1cc2OCOc2cc1Cc3nc4ccccc4[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N19 compound treatment 702646.0 119000.0 0.53 675060.0 112000.0 0.56 0.7702 0.9997 1973390 ChemDiv1_006641 COc1ccc(cc1OC)c2c(oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N20 compound treatment 694983.0 111000.0 0.5 643533.0 80900.0 0.4 0.6355 0.9942 1210544 ChemDiv1_006642 O=C(CSc1nc2CCCCc2cc1C#N)Nc3ccccc3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N21 compound treatment 701905.0 118000.0 0.53 652348.0 89700.0 0.44 0.6883 0.9962 1324593 ChemDiv1_006643 Cc1cc2nc(oc2cc1C)c3cc(NC(=O)c4sc5ccccc5c4Cl)ccc3O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N22 compound treatment 692921.0 109000.0 0.49 644875.0 82200.0 0.41 0.6337 0.9959 1973391 ChemDiv1_006644 Fc1ccccc1N2C(=O)NC(=O)/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N23 mock treatment 674579.0 90900.0 0.41 626524.0 63900.0 0.32 0.5114 0.9923 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 N24 mock treatment 302466.0 -281000.0 -1.26 395587.0 -167000.0 -0.83 -1.4754 -0.9793 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O01 compound treatment 648429.0 64700.0 0.29 584383.0 21700.0 0.11 0.281 0.9093 1973392 ChemDiv1_006645 CCOC(=O)c1nnn(c1CSc2nc3ccccc3s2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O02 compound treatment 632737.0 49000.0 0.22 553483.0 -9150.0 -0.05 0.1231 0.5494 1301014 ChemDiv1_006646 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2Cl)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O03 compound treatment 679473.0 95700.0 0.43 587414.0 24800.0 0.12 0.3899 0.8745 1973393 ChemDiv1_006647 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCCOc5cccc(C)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O04 compound treatment 630129.0 46400.0 0.21 575704.0 13100.0 0.06 0.1927 0.8855 1137863 ChemDiv1_006648 Fc1ccc(cc1Br)C2Nc3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O05 compound treatment 706670.0 123000.0 0.55 647558.0 84900.0 0.42 0.6866 0.9912 1973394 ChemDiv1_006649 COc1ccccc1OCCOc2ccc(cc2/C=C/3\C(=NN(C3=O)c4ccccc4)C)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O06 compound treatment 710595.0 127000.0 0.57 602577.0 39900.0 0.2 0.5415 0.9004 1973395 ChemDiv1_006650 COC(=O)c1ccc(cc1)n2c(C)cc(/C=C\3/C(=O)NC(=O)N(C3=O)c4ccc(OC)cc4)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O07 compound treatment 745396.0 162000.0 0.72 644345.0 81700.0 0.4 0.798 0.9623 1973396 ChemDiv1_006651 [O-][N+](=O)c1cc2OCOc2cc1C3Nc4ccc(cc4NC5=C3C(=O)CCC5)C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O08 compound treatment 693705.0 110000.0 0.49 600866.0 38200.0 0.19 0.482 0.9138 1945737 ChemDiv1_006652 O=C1C2CCCCC2C(=O)N1c3ccc4[nH]c(=S)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O09 compound treatment 716936.0 133000.0 0.6 647441.0 84800.0 0.42 0.7187 0.9853 1342490 ChemDiv1_006653 Cc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2c1C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O10 compound treatment 677036.0 93300.0 0.42 592555.0 29900.0 0.15 0.4002 0.9029 1973397 ChemDiv1_006654 COc1cc(/C=C/2\S/C(=N\C)/N(C)C2=O)ccc1Oc3ccc(cc3C#N)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O11 compound treatment 763607.0 180000.0 0.81 742516.0 180000.0 0.89 1.1995 0.9987 1973398 ChemDiv1_006655 CCOc1cc(/C=C/2\S\C(=N\C)\N(C)C2=O)cc(Cl)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O12 compound treatment 724489.0 141000.0 0.63 640861.0 78200.0 0.39 0.7196 0.9727 1973399 ChemDiv1_006656 C/N=C/1\S/C(=C\c2ccc(o2)c3cc(Cl)ccc3[N+](=O)[O-])/C(=O)N1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O13 compound treatment 760303.0 177000.0 0.79 687191.0 125000.0 0.62 0.9952 0.9925 1923956 ChemDiv1_006657 Cc1ccsc1/C=C/2\SC(=N)N(C2=O)c3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O14 compound treatment 688477.0 105000.0 0.47 632186.0 69600.0 0.34 0.5752 0.9885 1973400 ChemDiv1_006658 [O-][N+](=O)c1cc(ccc1N2CCN(CC2)C(=O)c3sc4ccccc4c3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O15 compound treatment 749245.0 166000.0 0.74 726284.0 164000.0 0.81 1.0972 0.999 1973401 ChemDiv1_006659 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3cc(Cl)ccc3[N+](=O)[O-])\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O16 compound treatment 692768.0 109000.0 0.49 618349.0 55700.0 0.28 0.5403 0.9636 1400774 ChemDiv1_006660 Cn1c(Sc2ncnn2Cc3ccccc3)nc4n(C)c(=O)n(C)c(=O)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O17 compound treatment 823441.0 240000.0 1.07 762762.0 200000.0 0.99 1.4598 0.9992 1926143 ChemDiv1_006661 OC(=O)c1cccc(c1)c2ccc(/C=C/3\SC(=N)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O18 compound treatment 711701.0 128000.0 0.57 633327.0 70700.0 0.35 0.6527 0.9721 1973402 ChemDiv1_006662 CCOc1cc(/C=C/2\NC(=S)NC2=O)cc(Br)c1OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O19 compound treatment 768987.0 185000.0 0.83 699666.0 137000.0 0.68 1.0664 0.9951 1973403 ChemDiv1_006663 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Br)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O20 compound treatment 703537.0 120000.0 0.54 637781.0 75100.0 0.37 0.6425 0.9841 1253659 ChemDiv1_006664 OC(=O)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)ccc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O21 compound treatment 710699.0 127000.0 0.57 649459.0 86800.0 0.43 0.706 0.9905 1494268 ChemDiv1_006665 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2C)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O22 compound treatment 710784.0 127000.0 0.57 629320.0 66700.0 0.33 0.6358 0.9666 1257969 ChemDiv1_006666 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(c3)C(=O)O)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O23 mock treatment 684685.0 101000.0 0.45 633597.0 71000.0 0.35 0.5681 0.9923 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 O24 mock treatment 494465.0 -89300.0 -0.4 448570.0 -114000.0 -0.57 -0.6821 -0.9856 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P01 compound treatment 576498.0 -7230.0 -0.03 534488.0 -28100.0 -0.14 -0.1215 -0.8486 1249048 ChemDiv1_006667 COc1ccc2[nH]c(SCC(=O)Nc3cc(NC(=O)CSc4nc5cc(OC)ccc5[nH]4)cc(c3)C(=O)O)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P02 compound treatment 631110.0 47400.0 0.21 526928.0 -35700.0 -0.18 0.0249 0.0902 1505672 ChemDiv1_006668 Cc1ccc(NC(=O)CC2SC(=O)NC2=O)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P03 compound treatment 620197.0 36500.0 0.16 558391.0 -4240.0 -0.02 0.1006 0.611 1973404 ChemDiv1_006669 COC(=O)C1=C(C)OC(=C(C#N)C1c2c(F)c(F)c(F)c(F)c2F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P04 compound treatment 633639.0 49900.0 0.22 547370.0 -15300.0 -0.08 0.1045 0.4431 1601984 ChemDiv1_006670 COc1ccc(cc1CN2CCOCC2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P05 compound treatment 639032.0 55300.0 0.25 552021.0 -10600.0 -0.05 0.1379 0.5448 1552457 ChemDiv1_006671 CCC(C)Nc1nc(NC(C)C)nc(Oc2ccc(cc2)C(=O)OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P06 compound treatment 638642.0 54900.0 0.25 566782.0 4150.0 0.02 0.1884 0.7635 1228047 ChemDiv1_006672 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P07 compound treatment 654876.0 71200.0 0.32 561422.0 -1210.0 -0.01 0.221 0.6936 1267312 ChemDiv1_006673 Cc1ccc(cc1)c2nnc(Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P08 compound treatment 662162.0 78400.0 0.35 580784.0 18100.0 0.09 0.3118 0.8604 1926800 ChemDiv1_006674 CCCN1C(Nc2ccccc2C1=O)c3ccc(OC)c(COc4ccc(cc4)[N+](=O)[O-])c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P09 compound treatment 655798.0 72100.0 0.32 567659.0 5020.0 0.02 0.2457 0.7594 1973405 ChemDiv1_006675 COCc1cc(C)nc(SCC(=O)Nc2ccccc2OC)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P10 compound treatment 684112.0 100000.0 0.45 581256.0 18600.0 0.09 0.383 0.8348 1973406 ChemDiv1_006676 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)n2NCc4ccc(OC(F)F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P11 compound treatment 672371.0 88600.0 0.4 573336.0 10700.0 0.05 0.3181 0.7945 1973407 ChemDiv1_006677 CCC1CCCCN1C(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P12 compound treatment 649083.0 65400.0 0.29 589857.0 27200.0 0.13 0.3022 0.9382 1973408 ChemDiv1_006678 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P13 compound treatment 649118.0 65400.0 0.29 581109.0 18500.0 0.09 0.2717 0.8859 1973409 ChemDiv1_006679 CCCCc1nnc(NC(=O)CCN2C(=O)/C(=C/c3ccc4OCOc4c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P14 compound treatment 665896.0 82200.0 0.37 594915.0 32300.0 0.16 0.3732 0.9304 1973410 ChemDiv1_006680 CCOC(=O)c1sc(NC(=O)Cn2c3ccccc3c(=O)c4ccccc24)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P15 compound treatment 649205.0 65500.0 0.29 587043.0 24400.0 0.12 0.2928 0.9233 1973411 ChemDiv1_006681 COC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P16 compound treatment 665373.0 81600.0 0.37 600380.0 37700.0 0.19 0.3907 0.9516 1973412 ChemDiv1_006682 COc1ccccc1Oc2ccc(cc2NC(=O)Cn3c4ccccc4c(=O)c5ccccc35)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P17 compound treatment 691833.0 108000.0 0.48 595073.0 32400.0 0.16 0.4558 0.8939 1973413 ChemDiv1_006683 COc1ccc(cc1OC)c2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P18 compound treatment 681701.0 98000.0 0.44 593452.0 30800.0 0.15 0.4181 0.9003 1973414 ChemDiv1_006684 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CC(N(C(=O)c4cccc(c4)[N+](=O)[O-])c5ccccc5)c6ccccc36 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P19 compound treatment 676575.0 92900.0 0.42 588755.0 26100.0 0.13 0.3854 0.8853 1973415 ChemDiv1_006685 CCN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(OC)c(OC)c4)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P20 compound treatment 658124.0 74400.0 0.33 592144.0 29500.0 0.15 0.3389 0.9317 1973416 ChemDiv1_006686 O=C(CSc1nc2CCCCCc2cc1C#N)Nc3ccccc3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P21 compound treatment 650168.0 66400.0 0.3 598595.0 36000.0 0.18 0.3363 0.97 1186170 ChemDiv1_006687 Cc1ccc(cc1NC(=O)c2sc3ccccc3c2Cl)c4nc5cc(Cl)ccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P22 compound treatment 638579.0 54900.0 0.25 592926.0 30300.0 0.15 0.2797 0.9721 1973417 ChemDiv1_006688 Fc1ccc(cc1)c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P23 mock treatment 640074.0 56300.0 0.25 592271.0 29600.0 0.15 0.2822 0.9668 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.605 P24 mock treatment 511896.0 -71800.0 -0.32 453522.0 -109000.0 -0.54 -0.6096 -0.9692 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A01 compound treatment 588058.0 -6120.0 -0.03 554753.0 -27500.0 -0.14 -0.1156 -0.8326 1973418 ChemDiv1_006689 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)ccc1OCc5ccc(cc5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A02 compound treatment 562001.0 -32200.0 -0.14 565927.0 -16300.0 -0.08 -0.159 -0.9627 1928687 ChemDiv1_006690 O=C(CCN1C(=O)/C(=C/c2cccs2)/SC1=S)Nc3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A03 compound treatment 566123.0 -28100.0 -0.13 555127.0 -27100.0 -0.13 -0.1838 -0.9994 1973419 ChemDiv1_006691 CCN(CC)c1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A04 compound treatment 878665.0 284000.0 1.27 843904.0 262000.0 1.3 1.8171 1.0 1973420 ChemDiv1_006692 Brc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A05 compound treatment 574932.0 -19200.0 -0.09 573179.0 -9060.0 -0.04 -0.0926 -0.9538 1973421 ChemDiv1_006693 CCN(CC)c1cc(Nc2ccc(Cl)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A06 compound treatment 611560.0 17400.0 0.08 629685.0 47400.0 0.24 0.2212 0.8935 1973422 ChemDiv1_006694 CN1C(=O)C(=Cc2cc(C)n(c2C)c3ccc(cc3C)[N+](=O)[O-])C(=O)N(C)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A07 compound treatment 590720.0 -3460.0 -0.02 601199.0 19000.0 0.09 0.0555 0.5828 1973423 ChemDiv1_006695 COc1ccccc1Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A08 compound treatment 639168.0 45000.0 0.2 642513.0 60300.0 0.3 0.3536 0.9816 1973424 ChemDiv1_006696 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A09 compound treatment 592395.0 -1780.0 -0.01 595856.0 13600.0 0.07 0.0421 0.6193 1973425 ChemDiv1_006697 COc1ccccc1Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A10 compound treatment 646214.0 52000.0 0.23 706034.0 124000.0 0.61 0.5984 0.9121 1973426 ChemDiv1_006698 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OC(=O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A11 compound treatment 605082.0 10900.0 0.05 606730.0 24500.0 0.12 0.1203 0.92 1973427 ChemDiv1_006699 COc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A12 compound treatment 607708.0 13500.0 0.06 629410.0 47200.0 0.23 0.2081 0.8619 1973428 ChemDiv1_006700 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A13 compound treatment 603572.0 9400.0 0.04 623500.0 41300.0 0.2 0.1743 0.8351 1973429 ChemDiv1_006701 [O-][N+](=O)c1c(Nc2ccc(cc2)c3ccccc3)cc(N4CCOCC4)c5nonc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A14 compound treatment 612426.0 18300.0 0.08 622523.0 40300.0 0.2 0.1989 0.9223 1502754 ChemDiv1_006702 COC(=O)c1ccc(CSc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2C#N)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A15 compound treatment 624036.0 29900.0 0.13 622073.0 39800.0 0.2 0.2341 0.982 1973430 ChemDiv1_006703 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCOCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A16 compound treatment 604018.0 9840.0 0.04 601015.0 18800.0 0.09 0.0969 0.9417 1973431 ChemDiv1_006704 Oc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A17 compound treatment 613438.0 19300.0 0.09 627694.0 45500.0 0.23 0.2202 0.9132 1518178 ChemDiv1_006705 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccccc2Cl)C(=O)Nc3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A18 compound treatment 612893.0 18700.0 0.08 633302.0 51100.0 0.25 0.2381 0.8936 1973432 ChemDiv1_006706 CCOC(=O)Cn1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A19 compound treatment 594670.0 495.0 0.0 594135.0 11900.0 0.06 0.0432 0.7332 1973433 ChemDiv1_006707 CCOC(=O)C1=CN(C=C(C1c2cc(Br)ccc2OC)C(=O)OCC)c3ccc(OCC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A20 compound treatment 593861.0 -314.0 0.0 604525.0 22300.0 0.11 0.0771 0.698 1973434 ChemDiv1_006708 CCOc1ccc(/C=C\2/C(=O)NC(=S)N(C2=O)c3ccc(Br)cc3)c(OCC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A21 compound treatment 587940.0 -6240.0 -0.03 598885.0 16600.0 0.08 0.0386 0.4431 1973435 ChemDiv1_006709 COc1cc(/C=C\2/SC(=S)N(CCC(=O)N3CCN(C)CC3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A22 compound treatment 579268.0 -14900.0 -0.07 559904.0 -22300.0 -0.11 -0.1254 -0.9707 1973436 ChemDiv1_006710 Cn1c2ccccc2c3nnc(SCC(=O)Nc4nc5ccc(cc5s4)[N+](=O)[O-])nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A23 mock treatment 565798.0 -28400.0 -0.13 563722.0 -18500.0 -0.09 -0.1547 -0.9872 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 A24 mock treatment 548671.0 -45500.0 -0.2 537573.0 -44700.0 -0.22 -0.3005 -0.9991 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B01 compound treatment 609259.0 15100.0 0.07 619815.0 37600.0 0.19 0.1794 0.9058 1973437 ChemDiv1_006711 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B02 compound treatment 604264.0 10100.0 0.05 622305.0 40100.0 0.2 0.1723 0.8464 1233873 ChemDiv1_006712 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B03 compound treatment 644293.0 50100.0 0.22 677507.0 95300.0 0.47 0.4924 0.9422 1973438 ChemDiv1_006713 Brc1ccc(cc1)N2C(=O)/C(=C/c3cccn3c4ccccc4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B04 compound treatment 609078.0 14900.0 0.07 650432.0 68200.0 0.34 0.286 0.8307 1605926 ChemDiv1_006714 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B05 compound treatment 642184.0 48000.0 0.21 693609.0 111000.0 0.55 0.5421 0.9155 1973439 ChemDiv1_006715 CCc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B06 compound treatment 618813.0 24600.0 0.11 689826.0 108000.0 0.53 0.4549 0.8357 1700200 ChemDiv1_006716 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Br)c3)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B07 compound treatment 1288629.0 694000.0 3.11 1393166.0 811000.0 4.02 5.0387 0.992 1973440 ChemDiv1_006717 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(CC=C)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B08 compound treatment 659100.0 64900.0 0.29 706334.0 124000.0 0.61 0.6402 0.9415 1548058 ChemDiv1_006718 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3Cl)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B09 compound treatment 656440.0 62300.0 0.28 732331.0 150000.0 0.74 0.7228 0.9103 1973441 ChemDiv1_006719 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3C)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B10 compound treatment 642577.0 48400.0 0.22 712196.0 130000.0 0.64 0.6084 0.8957 1267439 ChemDiv1_006720 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Cl)cc3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B11 compound treatment 637142.0 43000.0 0.19 730159.0 148000.0 0.73 0.6542 0.8635 1973442 ChemDiv1_006721 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(F)c3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B12 compound treatment 640623.0 46400.0 0.21 698197.0 116000.0 0.57 0.5532 0.9056 1469298 ChemDiv1_006722 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B13 compound treatment 677036.0 82900.0 0.37 729673.0 147000.0 0.73 0.7787 0.9506 1219279 ChemDiv1_006723 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B14 compound treatment 647506.0 53300.0 0.24 712789.0 131000.0 0.65 0.6261 0.9082 1714214 ChemDiv1_006724 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B15 compound treatment 649765.0 55600.0 0.25 752395.0 170000.0 0.84 0.772 0.8784 1511300 ChemDiv1_006725 CCOc1ccc(NC(=O)C(C)CSc2nc3ccc(NC(=O)CC)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B16 compound treatment 644135.0 50000.0 0.22 733451.0 151000.0 0.75 0.6878 0.8798 1608255 ChemDiv1_006726 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Br)cc3)C(=O)Nc4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B17 compound treatment 672266.0 78100.0 0.35 735206.0 153000.0 0.76 0.783 0.9383 1973443 ChemDiv1_006727 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B18 compound treatment 640585.0 46400.0 0.21 697788.0 116000.0 0.57 0.5517 0.9059 1485444 ChemDiv1_006728 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B19 compound treatment 652415.0 58200.0 0.26 712863.0 131000.0 0.65 0.6419 0.9201 1973444 ChemDiv1_006729 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B20 compound treatment 616547.0 22400.0 0.1 675141.0 92900.0 0.46 0.3962 0.8413 1183823 ChemDiv1_006730 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccc(C)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B21 compound treatment 631135.0 37000.0 0.17 695699.0 113000.0 0.56 0.5144 0.878 1716216 ChemDiv1_006731 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(c4ccccc4)c(n3)c5ccccc5)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B22 compound treatment 612449.0 18300.0 0.08 657156.0 74900.0 0.37 0.3203 0.8427 1973445 ChemDiv1_006732 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B23 mock treatment 616157.0 22000.0 0.1 658241.0 76000.0 0.38 0.3358 0.8629 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 B24 mock treatment 593204.0 -971.0 0.0 507928.0 -74300.0 -0.37 -0.2634 -0.7154 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C01 compound treatment 567065.0 -27100.0 -0.12 565560.0 -16700.0 -0.08 -0.1442 -0.9824 1973446 ChemDiv1_006733 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(Br)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C02 compound treatment 693674.0 99500.0 0.45 693345.0 111000.0 0.55 0.7041 0.9945 1973447 ChemDiv1_006734 Clc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C03 compound treatment 620062.0 25900.0 0.12 656753.0 74500.0 0.37 0.343 0.8864 1973448 ChemDiv1_006735 CCN(CC)c1cc(Nc2cccc(OC)c2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C04 compound treatment 1473284.0 879000.0 3.94 1365155.0 783000.0 3.88 5.5251 1.0 1973449 ChemDiv1_006736 Cc1cc(Br)ccc1N2C(=O)/C(=C/c3ccc(o3)N4CCCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C05 compound treatment 641833.0 47700.0 0.21 673158.0 90900.0 0.45 0.4693 0.9417 1973450 ChemDiv1_006737 COc1cccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C06 compound treatment 609332.0 15200.0 0.07 679367.0 97100.0 0.48 0.3882 0.7989 1973451 ChemDiv1_006738 Brc1ccc(cc1)C(=O)Oc2ccc(NC3=NS(=O)(=O)c4ccccc34)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C07 compound treatment 640457.0 46300.0 0.21 674659.0 92400.0 0.46 0.4702 0.9357 1973452 ChemDiv1_006739 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C08 compound treatment 659772.0 65600.0 0.29 701119.0 119000.0 0.59 0.6241 0.9483 1973453 ChemDiv1_006740 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OS(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C09 compound treatment 663556.0 69400.0 0.31 716814.0 135000.0 0.67 0.691 0.9396 1973454 ChemDiv1_006741 CCNc1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C10 compound treatment 651441.0 57300.0 0.26 705565.0 123000.0 0.61 0.6133 0.9256 1973455 ChemDiv1_006742 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OCc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C11 compound treatment 637726.0 43600.0 0.19 679257.0 97000.0 0.48 0.4777 0.921 1973456 ChemDiv1_006743 CN(c1ccccc1)c2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C12 compound treatment 629826.0 35700.0 0.16 710177.0 128000.0 0.63 0.561 0.8584 1973457 ChemDiv1_006744 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1OC(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C13 compound treatment 664749.0 70600.0 0.32 729508.0 147000.0 0.73 0.7393 0.9299 1973458 ChemDiv1_006745 COc1cccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C14 compound treatment 666048.0 71900.0 0.32 722601.0 140000.0 0.7 0.7192 0.9387 1582116 ChemDiv1_006746 CNC(=O)c1ccc(o1)c2sc3nc(N4CCOCC4)c5CCCCc5c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C15 compound treatment 698510.0 104000.0 0.47 724947.0 143000.0 0.71 0.8301 0.9798 1558534 ChemDiv1_006747 Clc1cc(ccc1NC(=O)Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C16 compound treatment 654286.0 60100.0 0.27 715125.0 133000.0 0.66 0.6558 0.9221 1946364 ChemDiv1_006748 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c(cc1OC)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C17 compound treatment 660752.0 66600.0 0.3 712963.0 131000.0 0.65 0.6686 0.938 1973459 ChemDiv1_006749 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C18 compound treatment 652851.0 58700.0 0.26 708893.0 127000.0 0.63 0.6294 0.9253 1973460 ChemDiv1_006750 COC(=O)COc1ccccc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C19 compound treatment 637415.0 43200.0 0.19 700447.0 118000.0 0.59 0.5509 0.8933 1973461 ChemDiv1_006751 Cc1ccc(cc1)C2NC(Cc3c2[nH]c4ccccc34)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C20 compound treatment 621432.0 27300.0 0.12 682327.0 100000.0 0.5 0.4369 0.8556 1701814 ChemDiv1_006752 CC1C=C(C)CC2C1C(=O)N(C2=O)c3ccc(cc3)C(=O)Nc4ccc(NC(=O)C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C21 compound treatment 669566.0 75400.0 0.34 716207.0 134000.0 0.66 0.7079 0.9508 1973462 ChemDiv1_006753 COc1cc(/C=C\2/SC(=S)N(CCC(=O)N3CCOCC3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C22 compound treatment 602641.0 8470.0 0.04 653524.0 71300.0 0.35 0.2765 0.7785 1973463 ChemDiv1_006754 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nnc4c5ccccc5n(CC=C)c4n3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C23 mock treatment 604196.0 10000.0 0.04 645194.0 63000.0 0.31 0.2522 0.8006 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 C24 mock treatment 595706.0 1530.0 0.01 522157.0 -60100.0 -0.3 -0.2056 -0.6906 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D01 compound treatment 610265.0 16100.0 0.07 632845.0 50600.0 0.25 0.2282 0.8749 1973464 ChemDiv1_006755 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D02 compound treatment 582326.0 -11800.0 -0.05 612776.0 30500.0 0.15 0.0695 0.4333 1315943 ChemDiv1_006756 COc1cccc(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D03 compound treatment 646950.0 52800.0 0.24 710485.0 128000.0 0.64 0.6163 0.9092 1973465 ChemDiv1_006757 Brc1ccc(cc1)n2cccc2/C=C/3\C(=O)NC(=S)N(C3=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D04 compound treatment 608717.0 14500.0 0.07 639481.0 57200.0 0.28 0.2465 0.8474 1432188 ChemDiv1_006758 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D05 compound treatment 689771.0 95600.0 0.43 727094.0 145000.0 0.72 0.81 0.9695 1973466 ChemDiv1_006759 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(Cl)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D06 compound treatment 607314.0 13100.0 0.06 663200.0 81000.0 0.4 0.3252 0.8022 1973467 ChemDiv1_006760 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D07 compound treatment 644062.0 49900.0 0.22 706360.0 124000.0 0.61 0.5927 0.906 1973468 ChemDiv1_006761 COc1cc(/C=C/2\C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)ccc1OCc4cccc(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D08 compound treatment 648446.0 54300.0 0.24 711328.0 129000.0 0.64 0.624 0.9121 1852042 ChemDiv1_006762 CC1=C(C(C2=C(CCCC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D09 compound treatment 755801.0 162000.0 0.72 835912.0 254000.0 1.26 1.4002 0.9656 1973469 ChemDiv1_006763 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(O)c(OCC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D10 compound treatment 648834.0 54700.0 0.24 715554.0 133000.0 0.66 0.64 0.9087 1852080 ChemDiv1_006764 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D11 compound treatment 686268.0 92100.0 0.41 763281.0 181000.0 0.9 0.9257 0.9378 1973470 ChemDiv1_006765 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Br)c(o3)N4CCOCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D12 compound treatment 633689.0 39500.0 0.18 668762.0 86500.0 0.43 0.4282 0.9234 1630028 ChemDiv1_006766 COc1ccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D13 compound treatment 665460.0 71300.0 0.32 744527.0 162000.0 0.8 0.7941 0.9181 1491586 ChemDiv1_006767 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D14 compound treatment 651517.0 57300.0 0.26 679602.0 97400.0 0.48 0.5226 0.9564 1450622 ChemDiv1_006768 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D15 compound treatment 693674.0 99500.0 0.45 742258.0 160000.0 0.79 0.8755 0.9628 1945672 ChemDiv1_006769 COc1ccc(Cl)cc1N(CC(=O)N2CCCCCC2)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D16 compound treatment 645146.0 51000.0 0.23 708404.0 126000.0 0.63 0.6033 0.9067 1852124 ChemDiv1_006770 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D17 compound treatment 666264.0 72100.0 0.32 739947.0 158000.0 0.78 0.7806 0.9235 1973471 ChemDiv1_006771 COc1ccc(cc1OC)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D18 compound treatment 641697.0 47500.0 0.21 710380.0 128000.0 0.63 0.5993 0.8951 1386387 ChemDiv1_006772 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D19 compound treatment 670500.0 76300.0 0.34 735693.0 153000.0 0.76 0.7791 0.9348 1973472 ChemDiv1_006773 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D20 compound treatment 622703.0 28500.0 0.13 707236.0 125000.0 0.62 0.5282 0.8354 1667579 ChemDiv1_006774 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cc(C)ccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D21 compound treatment 663460.0 69300.0 0.31 719572.0 137000.0 0.68 0.7004 0.9367 1494061 ChemDiv1_006775 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(c(o3)c4ccccc4)c5ccccc5)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D22 compound treatment 611626.0 17500.0 0.08 669449.0 87200.0 0.43 0.3607 0.8216 1973473 ChemDiv1_006776 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D23 mock treatment 626443.0 32300.0 0.14 664136.0 81900.0 0.41 0.389 0.9033 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 D24 mock treatment 573844.0 -20300.0 -0.09 225677.0 -357000.0 -1.77 -1.3133 -0.7426 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E01 compound treatment 611964.0 17800.0 0.08 603017.0 20800.0 0.1 0.1291 0.9919 1973474 ChemDiv1_006777 Cc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E02 compound treatment 1473036.0 879000.0 3.93 1237159.0 655000.0 3.24 5.0759 0.9954 1973475 ChemDiv1_006778 Clc1cccc(c1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E03 compound treatment 607640.0 13500.0 0.06 618218.0 36000.0 0.18 0.1687 0.8964 1973476 ChemDiv1_006779 CCN(CC)c1cc(N(C)c2ccccc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E04 compound treatment 1539458.0 945000.0 4.23 1304202.0 722000.0 3.58 5.521 0.9965 1973477 ChemDiv1_006780 Clc1cccc(N2C(=O)/C(=C/c3ccc(o3)N4CCCC4)/C(=O)NC2=S)c1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E05 compound treatment 664735.0 70600.0 0.32 652283.0 70000.0 0.35 0.4687 0.9989 1973478 ChemDiv1_006781 CCOc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E06 compound treatment 643868.0 49700.0 0.22 677003.0 94800.0 0.47 0.4892 0.9418 1973479 ChemDiv1_006782 [O-][N+](=O)c1cccc(c1)C(=O)Oc2cccc(NC3=NS(=O)(=O)c4ccccc34)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E07 compound treatment 664300.0 70100.0 0.31 694933.0 113000.0 0.56 0.6167 0.9629 1973480 ChemDiv1_006783 CN(C)c1cc(Nc2ccc(cc2)c3ccccc3)c([N+](=O)[O-])c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E08 compound treatment 686957.0 92800.0 0.42 715973.0 134000.0 0.66 0.7621 0.9747 1973481 ChemDiv1_006784 COc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E09 compound treatment 672890.0 78700.0 0.35 706179.0 124000.0 0.61 0.6833 0.9652 1973482 ChemDiv1_006785 CCNc1cc(Nc2ccc(OC)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E10 compound treatment 689647.0 95500.0 0.43 696051.0 114000.0 0.56 0.7009 0.9907 1973483 ChemDiv1_006786 COc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Br)c1OCc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E11 compound treatment 668642.0 74500.0 0.33 707790.0 126000.0 0.62 0.6755 0.9573 1973484 ChemDiv1_006787 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E12 compound treatment 736581.0 142000.0 0.64 840507.0 258000.0 1.28 1.3554 0.9482 1973485 ChemDiv1_006788 COc1ccc(cc1)C(=O)Oc2c(Cl)cc(/C=C/3\SC(=N)NC3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E13 compound treatment 674961.0 80800.0 0.36 721942.0 140000.0 0.69 0.7451 0.9542 1973486 ChemDiv1_006789 COc1ccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E14 compound treatment 668595.0 74400.0 0.33 703230.0 121000.0 0.6 0.6594 0.9616 1973487 ChemDiv1_006790 Cc1ccccc1n2c(=O)c3c4CCCCc4sc3n5c(SCC(=O)N)nnc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E15 compound treatment 969240.0 375000.0 1.68 970350.0 388000.0 1.92 2.5467 0.9977 1601464 ChemDiv1_006791 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E16 compound treatment 659771.0 65600.0 0.29 698905.0 117000.0 0.58 0.6163 0.9507 1973488 ChemDiv1_006792 COc1cc(OC)c(cc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E17 compound treatment 688732.0 94600.0 0.42 726875.0 145000.0 0.72 0.8059 0.9685 1250417 ChemDiv1_006793 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E18 compound treatment 671051.0 76900.0 0.34 715676.0 133000.0 0.66 0.7108 0.9537 1973489 ChemDiv1_006794 COc1cccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E19 compound treatment 674184.0 80000.0 0.36 693036.0 111000.0 0.55 0.6414 0.9786 1131798 ChemDiv1_006795 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCOCC4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E20 compound treatment 641219.0 47000.0 0.21 708435.0 126000.0 0.63 0.591 0.8958 1973490 ChemDiv1_006796 CN1CCN(CC1)c2ccc(/C=C\3/C(=NN(C3=O)c4cccc(c4)C(=O)O)C)cc2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E21 compound treatment 724593.0 130000.0 0.58 751855.0 170000.0 0.84 1.007 0.9842 1973491 ChemDiv1_006797 COc1cc(/C=C\2/SC(=S)N(CCC(=O)NC3=NCCS3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E22 compound treatment 641714.0 47500.0 0.21 686004.0 104000.0 0.51 0.514 0.9238 1973492 ChemDiv1_006798 [O-][N+](=O)c1ccc(Nc2csc(NC(=O)CSc3nnc4c5ccccc5n(CC=C)c4n3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E23 mock treatment 639392.0 45200.0 0.2 669245.0 87000.0 0.43 0.4479 0.9406 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 E24 mock treatment 615548.0 21400.0 0.1 523136.0 -59100.0 -0.29 -0.1394 -0.4525 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F01 compound treatment 588266.0 -5910.0 -0.03 591930.0 9690.0 0.05 0.0152 0.2782 1973493 ChemDiv1_006799 CN1C(=O)N(C)C(=O)C(=Cc2cc(C)n(c2C)c3cc(cc(c3)C(=O)O)C(=O)O)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F02 compound treatment 581845.0 -12300.0 -0.06 631247.0 49000.0 0.24 0.1326 0.5328 1555897 ChemDiv1_006800 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F03 compound treatment 636666.0 42500.0 0.19 694143.0 112000.0 0.55 0.5265 0.8983 1973494 ChemDiv1_006801 COc1ccc(cc1)N2C(=O)/C(=C/c3cccn3c4ccc(Cl)cc4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F04 compound treatment 620784.0 26600.0 0.12 664708.0 82500.0 0.41 0.3731 0.8768 1201108 ChemDiv1_006802 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F05 compound treatment 849889.0 256000.0 1.14 863256.0 281000.0 1.39 1.7938 0.9953 1973495 ChemDiv1_006803 Clc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F06 compound treatment 638000.0 43800.0 0.2 681291.0 99100.0 0.49 0.4857 0.9191 1973496 ChemDiv1_006804 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F07 compound treatment 667185.0 73000.0 0.33 726486.0 144000.0 0.71 0.7364 0.9371 1973497 ChemDiv1_006805 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F08 compound treatment 652543.0 58400.0 0.26 688432.0 106000.0 0.53 0.5567 0.9478 1852048 ChemDiv1_006806 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F09 compound treatment 665969.0 71800.0 0.32 730923.0 149000.0 0.74 0.7481 0.9309 1973498 ChemDiv1_006807 CCc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC(C)C(=O)O)cc3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F10 compound treatment 646638.0 52500.0 0.23 696619.0 114000.0 0.57 0.5667 0.924 1852087 ChemDiv1_006808 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F11 compound treatment 672412.0 78200.0 0.35 730490.0 148000.0 0.73 0.767 0.9426 1973499 ChemDiv1_006809 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3F)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F12 compound treatment 657335.0 63200.0 0.28 728489.0 146000.0 0.72 0.7122 0.9158 1376959 ChemDiv1_006810 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F13 compound treatment 690240.0 96100.0 0.43 712679.0 130000.0 0.65 0.761 0.9804 1727847 ChemDiv1_006811 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F14 compound treatment 641735.0 47600.0 0.21 725007.0 143000.0 0.71 0.6506 0.8809 1520173 ChemDiv1_006812 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F15 compound treatment 669835.0 75700.0 0.34 719905.0 138000.0 0.68 0.7217 0.9478 1227554 ChemDiv1_006813 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F16 compound treatment 640530.0 46400.0 0.21 713422.0 131000.0 0.65 0.6062 0.8887 1852128 ChemDiv1_006814 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(c3)[N+](=O)[O-])C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F17 compound treatment 683216.0 89000.0 0.4 734310.0 152000.0 0.75 0.8145 0.9557 1973500 ChemDiv1_006815 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F18 compound treatment 654162.0 60000.0 0.27 690818.0 109000.0 0.54 0.5702 0.9485 1438640 ChemDiv1_006816 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5ccc(Br)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F19 compound treatment 715416.0 121000.0 0.54 755150.0 173000.0 0.86 0.9895 0.9758 1615288 ChemDiv1_006817 CCOC(=O)COc1ccc(C=c2sc3=NC(=C(C(c4cccs4)n3c2=O)C(=O)OCC)C)cc1OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F20 compound treatment 643726.0 49600.0 0.22 703778.0 122000.0 0.6 0.5826 0.908 1652150 ChemDiv1_006818 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F21 compound treatment 641308.0 47100.0 0.21 695715.0 113000.0 0.56 0.5467 0.9105 1350182 ChemDiv1_006819 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc(N)s3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F22 compound treatment 625655.0 31500.0 0.14 690551.0 108000.0 0.54 0.4791 0.8635 1973501 ChemDiv1_006820 COC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F23 mock treatment 608160.0 14000.0 0.06 670929.0 88700.0 0.44 0.3549 0.7998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 F24 mock treatment 600051.0 5880.0 0.03 243045.0 -339000.0 -1.68 -1.1695 -0.696 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G01 compound treatment 598785.0 4610.0 0.02 596822.0 14600.0 0.07 0.0657 0.8741 1554461 ChemDiv1_006821 O=S(=O)(N1CCCCCC1)c2cccc3nonc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G02 compound treatment 1482133.0 888000.0 3.97 1493813.0 912000.0 4.52 6.0038 0.998 1973502 ChemDiv1_006822 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G03 compound treatment 645246.0 51100.0 0.23 649582.0 67300.0 0.33 0.3976 0.983 1973503 ChemDiv1_006823 CCN(CC)c1cc(Nc2ccc(SC#N)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G04 compound treatment 638165.0 44000.0 0.2 633311.0 51100.0 0.25 0.3181 0.9923 1973504 ChemDiv1_006824 Fc1ccccc1N2C(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G05 compound treatment 660956.0 66800.0 0.3 687657.0 105000.0 0.52 0.5807 0.965 1973505 ChemDiv1_006825 COc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G06 compound treatment 675529.0 81400.0 0.36 669509.0 87300.0 0.43 0.5632 0.9964 1973506 ChemDiv1_006826 [O-][N+](=O)c1cccc(c1)C(=O)Oc2ccccc2NC3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G07 compound treatment 676040.0 81900.0 0.37 710296.0 128000.0 0.63 0.7077 0.966 1973507 ChemDiv1_006827 CCOc1ccc(Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G08 compound treatment 696408.0 102000.0 0.46 660816.0 78600.0 0.39 0.5988 0.9968 1973508 ChemDiv1_006828 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G09 compound treatment 683254.0 89100.0 0.4 704246.0 122000.0 0.6 0.7093 0.9796 1973509 ChemDiv1_006829 CCNc1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G10 compound treatment 730834.0 137000.0 0.61 727528.0 145000.0 0.72 0.9415 0.9967 1973510 ChemDiv1_006830 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OCc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G11 compound treatment 685809.0 91600.0 0.41 693539.0 111000.0 0.55 0.6799 0.9894 1973511 ChemDiv1_006831 CCN(c1ccccc1)c2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G12 compound treatment 781767.0 188000.0 0.84 869081.0 287000.0 1.42 1.5986 0.9685 1973512 ChemDiv1_006832 CCOc1cc(/C=C/2\SC(=N)NC2=O)cc(Cl)c1OC(=O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G13 compound treatment 658834.0 64700.0 0.29 681579.0 99300.0 0.49 0.5526 0.968 1973513 ChemDiv1_006833 CN(c1ccccc1)c2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G14 compound treatment 682501.0 88300.0 0.4 732070.0 150000.0 0.74 0.8044 0.9565 1973514 ChemDiv1_006834 O=C1C2C(C3CCC2C=C3)C(=O)N1c4nccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G15 compound treatment 1618400.0 1020000.0 4.58 1861595.0 1280000.0 6.34 7.7234 0.9874 1973515 ChemDiv1_006835 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4cn(CC#N)c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G16 compound treatment 698020.0 104000.0 0.46 759765.0 178000.0 0.88 0.9506 0.9556 1945940 ChemDiv1_006836 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G17 compound treatment 700412.0 106000.0 0.48 728323.0 146000.0 0.72 0.848 0.9793 1935926 ChemDiv1_006837 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G18 compound treatment 658974.0 64800.0 0.29 709790.0 128000.0 0.63 0.6519 0.9376 1973516 ChemDiv1_006838 COc1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G19 compound treatment 696217.0 102000.0 0.46 720993.0 139000.0 0.69 0.809 0.9803 1940449 ChemDiv1_006839 O=C(CC1S/C(=N\c2ccccc2)/N(C1=O)c3ccccc3)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G20 compound treatment 648956.0 54800.0 0.25 702211.0 120000.0 0.59 0.5936 0.9234 1951238 ChemDiv1_006840 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)[N+](=O)[O-])c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G21 compound treatment 697329.0 103000.0 0.46 664699.0 82500.0 0.41 0.6154 0.9981 1927911 ChemDiv1_006841 COc1cc(/C=C\2/SC(=S)N(CCC(=O)Nc3nnc(C)s3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G22 compound treatment 620389.0 26200.0 0.12 679684.0 97400.0 0.48 0.4243 0.8541 1678680 ChemDiv1_006842 CCC(Sc1nc2ccccc2s1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G23 mock treatment 636767.0 42600.0 0.19 671504.0 89300.0 0.44 0.4475 0.9293 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 G24 mock treatment 583037.0 -11100.0 -0.05 539869.0 -42400.0 -0.21 -0.1837 -0.8514 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H01 compound treatment 583821.0 -10400.0 -0.05 602803.0 20600.0 0.1 0.0393 0.3508 1973517 ChemDiv1_006843 Brc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)oc1N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H02 compound treatment 602070.0 7890.0 0.04 621052.0 38800.0 0.19 0.161 0.8233 1549636 ChemDiv1_006844 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H03 compound treatment 669784.0 75600.0 0.34 689781.0 108000.0 0.53 0.616 0.976 1973518 ChemDiv1_006845 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H04 compound treatment 614592.0 20400.0 0.09 652256.0 70000.0 0.35 0.3099 0.8639 1149125 ChemDiv1_006846 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H05 compound treatment 747608.0 153000.0 0.69 751574.0 169000.0 0.84 1.0788 0.9951 1973519 ChemDiv1_006847 CCOc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H06 compound treatment 629747.0 35600.0 0.16 675164.0 92900.0 0.46 0.4381 0.8994 1973520 ChemDiv1_006848 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H07 compound treatment 913171.0 319000.0 1.43 994722.0 412000.0 2.04 2.4546 0.9846 1973521 ChemDiv1_006849 Brc1cccc(c1)N2C(=O)/C(=C/c3cccn3c4ccccc4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H08 compound treatment 648011.0 53800.0 0.24 683588.0 101000.0 0.5 0.5254 0.9435 1852049 ChemDiv1_006850 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H09 compound treatment 705172.0 111000.0 0.5 734578.0 152000.0 0.75 0.885 0.9794 1973522 ChemDiv1_006851 Brc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3)oc1N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H10 compound treatment 652102.0 57900.0 0.26 679563.0 97300.0 0.48 0.5243 0.9577 1852089 ChemDiv1_006852 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H11 compound treatment 656119.0 61900.0 0.28 683836.0 102000.0 0.5 0.552 0.9605 1219784 ChemDiv1_006853 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5cc(OC)c(Br)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H12 compound treatment 658115.0 63900.0 0.29 684520.0 102000.0 0.51 0.5607 0.9634 1428479 ChemDiv1_006854 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H13 compound treatment 693256.0 99100.0 0.44 731476.0 149000.0 0.74 0.8364 0.9701 1126349 ChemDiv1_006855 Cn1ccnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4F)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H14 compound treatment 644095.0 49900.0 0.22 711990.0 130000.0 0.64 0.6125 0.9001 1472091 ChemDiv1_006856 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H15 compound treatment 660585.0 66400.0 0.3 720857.0 139000.0 0.69 0.6958 0.9298 1169056 ChemDiv1_006857 COc1ccc(cc1OC)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H16 compound treatment 646691.0 52500.0 0.24 698328.0 116000.0 0.58 0.5729 0.9221 1681353 ChemDiv1_006858 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H17 compound treatment 676428.0 82300.0 0.37 726497.0 144000.0 0.71 0.7657 0.9524 1973523 ChemDiv1_006859 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H18 compound treatment 630419.0 36200.0 0.16 706934.0 125000.0 0.62 0.5515 0.8635 1852148 ChemDiv1_006860 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5nc6ccccc6s5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H19 compound treatment 671228.0 77100.0 0.34 730656.0 148000.0 0.74 0.7638 0.9405 1973524 ChemDiv1_006861 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H20 compound treatment 643787.0 49600.0 0.22 680609.0 98400.0 0.49 0.5016 0.9367 1683872 ChemDiv1_006862 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cccc(C)n5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H21 compound treatment 685045.0 90900.0 0.41 719176.0 137000.0 0.68 0.7673 0.9701 1973525 ChemDiv1_006863 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(cc(c3C#N)C(F)(F)F)c4ccccc4)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H22 compound treatment 617748.0 23600.0 0.11 668456.0 86200.0 0.43 0.3766 0.8561 1973526 ChemDiv1_006864 COc1cccc(C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H23 mock treatment 631066.0 36900.0 0.17 663227.0 81000.0 0.4 0.4005 0.923 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 H24 mock treatment 588740.0 -5440.0 -0.02 533422.0 -48800.0 -0.24 -0.1882 -0.7743 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I01 compound treatment 579083.0 -15100.0 -0.07 589834.0 7600.0 0.04 -0.0212 -0.2736 1405997 ChemDiv1_006865 CCN(CC)S(=O)(=O)c1cccc2nonc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I02 compound treatment 1548104.0 954000.0 4.27 1470701.0 888000.0 4.4 6.1316 0.9999 1973527 ChemDiv1_006866 Clc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I03 compound treatment 588367.0 -5810.0 -0.03 561093.0 -21100.0 -0.1 -0.0924 -0.8566 1973528 ChemDiv1_006867 CCN(CC)c1cc(N(CC)c2ccccc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I04 compound treatment 731549.0 137000.0 0.61 771404.0 189000.0 0.94 1.0975 0.9791 1973529 ChemDiv1_006868 CN1C(=O)C(=Cc2ccc(o2)c3ccc(C)cc3Br)C(=O)N(C)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I05 compound treatment 637558.0 43400.0 0.19 650883.0 68600.0 0.34 0.3778 0.9647 1973530 ChemDiv1_006869 CN(c1ccccc1)c2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I06 compound treatment 649564.0 55400.0 0.25 668044.0 85800.0 0.43 0.4759 0.9671 1973531 ChemDiv1_006870 Clc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I07 compound treatment 684748.0 90600.0 0.41 696322.0 114000.0 0.57 0.6863 0.9867 1973532 ChemDiv1_006871 COc1ccc(Nc2cc(N(C)C)c3nonc3c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I08 compound treatment 701165.0 107000.0 0.48 694128.0 112000.0 0.55 0.7306 0.9974 1973533 ChemDiv1_006872 CCOc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OS(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I09 compound treatment 676703.0 82500.0 0.37 711349.0 129000.0 0.64 0.7135 0.966 1973534 ChemDiv1_006873 CCNc1cc(Nc2ccc(Br)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I10 compound treatment 661649.0 67500.0 0.3 679161.0 96900.0 0.48 0.5531 0.975 1973535 ChemDiv1_006874 Clc1ccc(cc1)C(=O)Oc2cccc(/C=C/3\SC(=N)NC3=O)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I11 compound treatment 695399.0 101000.0 0.45 698444.0 116000.0 0.58 0.7275 0.993 1973536 ChemDiv1_006875 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I12 compound treatment 658632.0 64500.0 0.29 678483.0 96200.0 0.48 0.5412 0.9711 1623773 ChemDiv1_006876 CCOC(=O)CSc1nc(N2CCCCC2)c3CCCCc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I13 compound treatment 660472.0 66300.0 0.3 706655.0 124000.0 0.62 0.6457 0.9439 1973537 ChemDiv1_006877 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCOCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I14 compound treatment 680464.0 86300.0 0.39 710480.0 128000.0 0.64 0.7223 0.9715 1973538 ChemDiv1_006878 ClC1=CCC2C(C1)C(=O)N(CCN3CCN(CCN4C(=O)C5CC=C(Cl)CC5C4=O)CC3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I15 compound treatment 699082.0 105000.0 0.47 751141.0 169000.0 0.84 0.9237 0.9627 1973539 ChemDiv1_006879 Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I16 compound treatment 2627043.0 2030000.0 9.1 2339560.0 1760000.0 8.71 12.5903 0.9998 1973540 ChemDiv1_006880 Brc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I17 compound treatment 702405.0 108000.0 0.48 725972.0 144000.0 0.71 0.8461 0.9824 1973541 ChemDiv1_006881 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(OCC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I18 compound treatment 673050.0 78900.0 0.35 713316.0 131000.0 0.65 0.7088 0.959 1973542 ChemDiv1_006882 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)c(cc1OC)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I19 compound treatment 668985.0 74800.0 0.33 718544.0 136000.0 0.68 0.7143 0.9476 1973543 ChemDiv1_006883 COc1cccc(/C=C\2/SC(=O)N(CCC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I20 compound treatment 661849.0 67700.0 0.3 711328.0 129000.0 0.64 0.6664 0.9417 1927381 ChemDiv1_006884 CCOC(=O)c1ccc(cc1)c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(cc4)S(=O)(=O)N)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I21 compound treatment 717603.0 123000.0 0.55 756352.0 174000.0 0.86 1.0006 0.9768 1928148 ChemDiv1_006885 COc1cc(/C=C\2/SC(=S)N(CCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I22 compound treatment 648817.0 54600.0 0.24 682187.0 99900.0 0.5 0.5231 0.9472 1973544 ChemDiv1_006886 CCC(Sc1nncn1C)C(=O)Nc2ccc(cc2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I23 mock treatment 649394.0 55200.0 0.25 671354.0 89100.0 0.44 0.4869 0.9624 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 I24 mock treatment 600257.0 6080.0 0.03 509436.0 -72800.0 -0.36 -0.2358 -0.6519 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J01 compound treatment 586932.0 -7240.0 -0.03 588801.0 6560.0 0.03 1.0E-4 0.0014 1973545 ChemDiv1_006887 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J02 compound treatment 599250.0 5070.0 0.02 605105.0 22900.0 0.11 0.0962 0.8323 1341254 ChemDiv1_006888 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J03 compound treatment 622888.0 28700.0 0.13 654069.0 71800.0 0.36 0.3425 0.9053 1973546 ChemDiv1_006889 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OC(C)C(=O)O)cc3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J04 compound treatment 616622.0 22400.0 0.1 656383.0 74100.0 0.37 0.3308 0.8686 1404566 ChemDiv1_006890 COc1cccc(C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccc(Br)cc5s4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J05 compound treatment 696066.0 102000.0 0.46 729409.0 147000.0 0.73 0.838 0.9745 1973547 ChemDiv1_006891 Cc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J06 compound treatment 626687.0 32500.0 0.15 641987.0 59700.0 0.3 0.3122 0.9466 1973548 ChemDiv1_006892 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C(F)(F)F)C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J07 compound treatment 662717.0 68500.0 0.31 709957.0 128000.0 0.63 0.6643 0.9448 1973549 ChemDiv1_006893 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cc(C)cc(C)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J08 compound treatment 657039.0 62900.0 0.28 672923.0 90700.0 0.45 0.5166 0.9746 1852050 ChemDiv1_006894 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J09 compound treatment 959475.0 365000.0 1.64 974664.0 392000.0 1.94 2.5309 0.9963 1973550 ChemDiv1_006895 Cc1ccccc1N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J10 compound treatment 635701.0 41500.0 0.19 681762.0 99500.0 0.49 0.4801 0.9111 1428037 ChemDiv1_006896 CCN(CC)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J11 compound treatment 638081.0 43900.0 0.2 659510.0 77300.0 0.38 0.4097 0.952 1973551 ChemDiv1_006897 COC(=O)C1=CN(Cc2ccc(OC)cc2)C=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J12 compound treatment 661504.0 67300.0 0.3 682549.0 100000.0 0.5 0.5645 0.9713 1295220 ChemDiv1_006898 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(F)cc3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J13 compound treatment 681430.0 87300.0 0.39 701389.0 119000.0 0.59 0.6936 0.9799 1469846 ChemDiv1_006899 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCc4ccccc4Cl)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J14 compound treatment 658227.0 64100.0 0.29 685020.0 103000.0 0.51 0.5628 0.9631 1719080 ChemDiv1_006900 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J15 compound treatment 682529.0 88400.0 0.4 700427.0 118000.0 0.59 0.6937 0.9818 1973552 ChemDiv1_006901 FC(F)(F)c1cc(ccc1Cl)N(CC(=O)N2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J16 compound treatment 647402.0 53200.0 0.24 707308.0 125000.0 0.62 0.6066 0.9138 1553756 ChemDiv1_006902 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J17 compound treatment 654135.0 60000.0 0.27 714807.0 133000.0 0.66 0.6542 0.9221 1973553 ChemDiv1_006903 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J18 compound treatment 654441.0 60300.0 0.27 699812.0 118000.0 0.58 0.6026 0.9388 1462189 ChemDiv1_006904 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5nc6ccc(Br)cc6s5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J19 compound treatment 661558.0 67400.0 0.3 692459.0 110000.0 0.55 0.5994 0.9609 1973554 ChemDiv1_006905 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J20 compound treatment 641586.0 47400.0 0.21 683149.0 101000.0 0.5 0.5035 0.9272 1436311 ChemDiv1_006906 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccs3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J21 compound treatment 653692.0 59500.0 0.27 699194.0 117000.0 0.58 0.5981 0.9379 1533227 ChemDiv1_006907 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(C)cc(C)c3C#N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J22 compound treatment 589852.0 -4320.0 -0.02 659230.0 77000.0 0.38 0.256 0.6704 1973555 ChemDiv1_006908 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J23 mock treatment 620141.0 26000.0 0.12 656414.0 74200.0 0.37 0.342 0.8874 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 J24 mock treatment 606033.0 11900.0 0.05 503636.0 -78600.0 -0.39 -0.2378 -0.6051 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K01 compound treatment 589651.0 -4520.0 -0.02 586728.0 4490.0 0.02 0.0014 0.0469 1973556 ChemDiv1_006909 CCNS(=O)(=O)c1cccc2nonc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K02 compound treatment 860193.0 266000.0 1.19 848260.0 266000.0 1.32 1.7739 0.9987 1973557 ChemDiv1_006910 O=C1NC(=O)/C(=C\c2ccc(o2)N3CCCCC3)/C(=O)N1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K03 compound treatment 642646.0 48500.0 0.22 651683.0 69400.0 0.34 0.3967 0.9753 1973558 ChemDiv1_006911 CCN(CC)c1cc(Nc2ccc(Br)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K04 compound treatment 627266.0 33100.0 0.15 658821.0 76600.0 0.38 0.373 0.9159 1973559 ChemDiv1_006912 CN1C(=O)C(=Cc2ccc(o2)c3ccc(cc3Br)[N+](=O)[O-])C(=O)N(C)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K05 compound treatment 674712.0 80500.0 0.36 639939.0 57700.0 0.29 0.457 0.9934 1973560 ChemDiv1_006913 [O-][N+](=O)c1c(Nc2ccc(SC#N)cc2)cc(N3CCCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K06 compound treatment 663597.0 69400.0 0.31 676314.0 94100.0 0.47 0.5493 0.9806 1973561 ChemDiv1_006914 COc1cc(C=C2C(=O)NC(=S)NC2=O)cc(Cl)c1OCc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K07 compound treatment 655615.0 61400.0 0.28 704462.0 122000.0 0.61 0.6226 0.9362 1973562 ChemDiv1_006915 CN(C)c1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K08 compound treatment 659668.0 65500.0 0.29 699685.0 117000.0 0.58 0.6187 0.9497 1973563 ChemDiv1_006916 Clc1cc(C=C2C(=O)NC(=O)NC2=O)cc(Cl)c1OC(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K09 compound treatment 670860.0 76700.0 0.34 698020.0 116000.0 0.57 0.6483 0.9699 1973564 ChemDiv1_006917 CCNc1cc(Nc2ccccc2OC)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K10 compound treatment 671280.0 77100.0 0.35 666236.0 84000.0 0.42 0.5383 0.9957 1973565 ChemDiv1_006918 Clc1ccc(cc1)C(=O)Oc2ccc(/C=C/3\SC(=N)NC3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K11 compound treatment 687349.0 93200.0 0.42 718844.0 137000.0 0.68 0.7734 0.973 1973566 ChemDiv1_006919 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K12 compound treatment 631160.0 37000.0 0.17 635333.0 53100.0 0.26 0.3031 0.9751 1239307 ChemDiv1_006920 CC(C)CCSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K13 compound treatment 679630.0 85500.0 0.38 697429.0 115000.0 0.57 0.674 0.9811 1973567 ChemDiv1_006921 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCOCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K14 compound treatment 713977.0 120000.0 0.54 728929.0 147000.0 0.73 0.893 0.9888 1973568 ChemDiv1_006922 COC(=O)c1ccc(c(C)c1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K15 compound treatment 672749.0 78600.0 0.35 707122.0 125000.0 0.62 0.6862 0.9642 1973569 ChemDiv1_006923 COc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)cc(Br)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K16 compound treatment 827644.0 233000.0 1.05 848252.0 266000.0 1.32 1.6708 0.9934 1973570 ChemDiv1_006924 Cc1[nH]c2ccccc2c1/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K17 compound treatment 688364.0 94200.0 0.42 727621.0 145000.0 0.72 0.8074 0.9675 1973571 ChemDiv1_006925 CCOC(=O)C1=CN(C=C(C1c2cc(Br)ccc2OC)C(=O)OCC)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K18 compound treatment 1713757.0 1120000.0 5.01 1664041.0 1080000.0 5.36 7.3332 0.9994 1973572 ChemDiv1_006926 CN(C)c1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K19 compound treatment 679042.0 84900.0 0.38 734651.0 152000.0 0.76 0.8025 0.9495 1973573 ChemDiv1_006927 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccc3C(F)(F)F)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K20 compound treatment 666370.0 72200.0 0.32 639222.0 57000.0 0.28 0.4281 0.9977 1973574 ChemDiv1_006928 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)S(=O)(=O)N)c4ccc(C)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K21 compound treatment 737973.0 144000.0 0.64 795490.0 213000.0 1.06 1.2022 0.9718 1973575 ChemDiv1_006929 CCOC(=O)c1c(NC(=O)CCN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S)sc4CCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K22 compound treatment 645362.0 51200.0 0.23 683404.0 101000.0 0.5 0.5164 0.9371 1973576 ChemDiv1_006930 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nc(c(C#N)c(=O)[nH]3)c4ccccc4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K23 mock treatment 663565.0 69400.0 0.31 662694.0 80500.0 0.4 0.5015 0.9924 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 K24 mock treatment 625854.0 31700.0 0.14 576322.0 -5920.0 -0.03 0.0796 0.5494 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L01 compound treatment 570006.0 -24200.0 -0.11 580690.0 -1550.0 -0.01 -0.0819 -0.7553 1973577 ChemDiv1_006931 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Cl)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L02 compound treatment 596446.0 2270.0 0.01 627928.0 45700.0 0.23 0.1672 0.7381 1358742 ChemDiv1_006932 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L03 compound treatment 655888.0 61700.0 0.28 664827.0 82600.0 0.41 0.4846 0.9817 1973578 ChemDiv1_006933 Brc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)oc1N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L04 compound treatment 620780.0 26600.0 0.12 647133.0 64900.0 0.32 0.3115 0.9087 1482046 ChemDiv1_006934 COc1ccccc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L05 compound treatment 667587.0 73400.0 0.33 681979.0 99700.0 0.49 0.5818 0.9804 1973579 ChemDiv1_006935 CCc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L06 compound treatment 618127.0 24000.0 0.11 642954.0 60700.0 0.3 0.2885 0.9035 1852025 ChemDiv1_006936 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(cc3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L07 compound treatment 643766.0 49600.0 0.22 693236.0 111000.0 0.55 0.5458 0.9204 1973580 ChemDiv1_006937 CCOc1cccc(c1)N2C(=O)NC(=O)/C(=C\c3ccc(OC(C)C(=O)O)cc3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L08 compound treatment 635324.0 41100.0 0.18 668175.0 85900.0 0.43 0.4313 0.9298 1852051 ChemDiv1_006938 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L09 compound treatment 671378.0 77200.0 0.35 689948.0 108000.0 0.53 0.6217 0.9779 1973581 ChemDiv1_006939 COc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc(CC=C)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L10 compound treatment 668832.0 74700.0 0.33 677022.0 94800.0 0.47 0.5683 0.9861 1469193 ChemDiv1_006940 CCN(CC)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L11 compound treatment 658412.0 64200.0 0.29 673966.0 91700.0 0.45 0.5246 0.9756 1142911 ChemDiv1_006941 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4NC3c5ccc(OC(=O)C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L12 compound treatment 630084.0 35900.0 0.16 679779.0 97500.0 0.48 0.4553 0.8942 1714276 ChemDiv1_006942 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L13 compound treatment 649393.0 55200.0 0.25 663867.0 81600.0 0.4 0.4607 0.9721 1973582 ChemDiv1_006943 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccc(OC)cc3[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L14 compound treatment 628459.0 34300.0 0.15 679008.0 96800.0 0.48 0.4475 0.889 1590399 ChemDiv1_006944 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L15 compound treatment 670706.0 76500.0 0.34 710469.0 128000.0 0.64 0.6914 0.958 1973583 ChemDiv1_006945 CCOc1ccc(cc1)N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L16 compound treatment 653944.0 59800.0 0.27 673102.0 90900.0 0.45 0.5075 0.9691 1720467 ChemDiv1_006946 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L17 compound treatment 628116.0 33900.0 0.15 704529.0 122000.0 0.61 0.5358 0.8579 1973584 ChemDiv1_006947 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L18 compound treatment 625562.0 31400.0 0.14 669031.0 86800.0 0.43 0.4034 0.8918 1672165 ChemDiv1_006948 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccnc3)C(=O)Nc4nc5ccc(Br)cc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L19 compound treatment 642984.0 48800.0 0.22 677945.0 95700.0 0.47 0.4897 0.9381 1290421 ChemDiv1_006949 Cc1nn(C(=O)CCN2C(=O)c3ccccc3C2=O)c(C)c1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L20 compound treatment 640117.0 45900.0 0.21 676509.0 94300.0 0.47 0.4756 0.9321 1154110 ChemDiv1_006950 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccsc3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L21 compound treatment 670790.0 76600.0 0.34 675941.0 93700.0 0.46 0.5707 0.9889 1587713 ChemDiv1_006951 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCc4cc3C#N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L22 compound treatment 657402.0 63200.0 0.28 677174.0 94900.0 0.47 0.5327 0.9705 1973585 ChemDiv1_006952 COC(=O)C1=C(N)OC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L23 mock treatment 628840.0 34700.0 0.16 657550.0 75300.0 0.37 0.3735 0.9244 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 L24 mock treatment 606707.0 12500.0 0.06 356465.0 -226000.0 -1.12 -0.7512 -0.6708 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M01 compound treatment 596530.0 2350.0 0.01 601057.0 18800.0 0.09 0.0734 0.7821 1973586 ChemDiv1_006953 CCCCNS(=O)(=O)c1cccc2nonc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M02 compound treatment 694783.0 101000.0 0.45 664044.0 81800.0 0.41 0.605 0.9986 1973587 ChemDiv1_006954 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCCCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M03 compound treatment 652269.0 58100.0 0.26 657510.0 75300.0 0.37 0.4476 0.9845 1973588 ChemDiv1_006955 CCN(CC)c1cc(Nc2ccc(C)c(Cl)c2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M04 compound treatment 701461.0 107000.0 0.48 692792.0 111000.0 0.55 0.7268 0.9979 1973589 ChemDiv1_006956 CCOC(=O)c1ccc(cc1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M05 compound treatment 623013.0 28800.0 0.13 659104.0 76900.0 0.38 0.3605 0.8967 1973590 ChemDiv1_006957 [O-][N+](=O)c1c(Nc2ccc(Br)cc2)cc(N3CCCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M06 compound treatment 648891.0 54700.0 0.24 674579.0 92300.0 0.46 0.4967 0.9571 1973591 ChemDiv1_006958 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M07 compound treatment 673205.0 79000.0 0.35 705348.0 123000.0 0.61 0.6814 0.9665 1973592 ChemDiv1_006959 CN(C)c1cc(Nc2ccc(SC#N)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M08 compound treatment 639727.0 45600.0 0.2 689618.0 107000.0 0.53 0.5203 0.9134 1973593 ChemDiv1_006960 COc1ccc(cc1)C(=O)Oc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M09 compound treatment 633111.0 38900.0 0.17 687255.0 105000.0 0.52 0.4911 0.8951 1973594 ChemDiv1_006961 CCNc1cc(Nc2ccc(Cl)cc2)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M10 compound treatment 686849.0 92700.0 0.41 716383.0 134000.0 0.66 0.7632 0.9743 1973595 ChemDiv1_006962 COc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M11 compound treatment 684612.0 90400.0 0.4 709790.0 128000.0 0.63 0.7331 0.9768 1973596 ChemDiv1_006963 COc1ccccc1Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M12 compound treatment 644323.0 50100.0 0.22 664772.0 82500.0 0.41 0.4478 0.9601 1973597 ChemDiv1_006964 CCOC(=O)C(C)Sc1nc(N2CCOCC2)c3CCCCc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M13 compound treatment 678140.0 84000.0 0.38 708112.0 126000.0 0.62 0.7067 0.9706 1973598 ChemDiv1_006965 CCN(c1ccccc1)c2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M14 compound treatment 689234.0 95100.0 0.43 708602.0 126000.0 0.63 0.7435 0.9823 1973599 ChemDiv1_006966 COC(=O)c1cccc(c1C)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M15 compound treatment 691512.0 97300.0 0.44 739959.0 158000.0 0.78 0.8606 0.962 1973600 ChemDiv1_006967 CCOc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3F)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M16 compound treatment 679549.0 85400.0 0.38 706661.0 124000.0 0.62 0.7061 0.9736 1973601 ChemDiv1_006968 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M17 compound treatment 685654.0 91500.0 0.41 738158.0 156000.0 0.77 0.8357 0.956 1700475 ChemDiv1_006969 COc1ccccc1NC(=O)C2=C(C)NC3=C(C2c4cc(OC)c(OC)c(OC)c4)C(=O)CCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M18 compound treatment 673571.0 79400.0 0.36 670678.0 88400.0 0.44 0.5611 0.9946 1973602 ChemDiv1_006970 COC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M19 compound treatment 698222.0 104000.0 0.47 736283.0 154000.0 0.76 0.8689 0.9719 1973603 ChemDiv1_006971 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(cc3)C(=O)C)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M20 compound treatment 646699.0 52500.0 0.24 691328.0 109000.0 0.54 0.5484 0.9305 1973604 ChemDiv1_006972 COC(=O)c1cccc(c1)c2ccc(/C=C\3/C(=NN(C3=O)c4ccc(C)c(Cl)c4)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M21 compound treatment 845753.0 252000.0 1.13 910464.0 328000.0 1.63 1.946 0.9839 1973605 ChemDiv1_006973 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3sc4CCCCc4c3C(=O)N)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M22 compound treatment 655014.0 60800.0 0.27 677188.0 95000.0 0.47 0.5252 0.9662 1973606 ChemDiv1_006974 CCCc1nnc(NC(=O)CSc2nc(c(C#N)c(=O)[nH]2)c3cccc(OC)c3)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M23 mock treatment 628037.0 33900.0 0.15 664214.0 82000.0 0.41 0.3943 0.9097 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 M24 mock treatment 443367.0 -151000.0 -0.68 423759.0 -158000.0 -0.79 -1.0325 -0.9972 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N01 compound treatment 583594.0 -10600.0 -0.05 576943.0 -5290.0 -0.03 -0.052 -0.9611 1973607 ChemDiv1_006975 OC(=O)COc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N02 compound treatment 591636.0 -2540.0 -0.01 604772.0 22500.0 0.11 0.0709 0.6318 1405780 ChemDiv1_006976 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N03 compound treatment 757730.0 164000.0 0.73 823512.0 241000.0 1.2 1.3629 0.9723 1973608 ChemDiv1_006977 CCOc1cccc(c1)N2C(=O)/C(=C/c3cc(CC=C)c(O)c(OCC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N04 compound treatment 608019.0 13800.0 0.06 630563.0 48300.0 0.24 0.2131 0.8617 1726565 ChemDiv1_006978 COc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N05 compound treatment 654886.0 60700.0 0.27 664639.0 82400.0 0.41 0.4808 0.9805 1973609 ChemDiv1_006979 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N06 compound treatment 620453.0 26300.0 0.12 606135.0 23900.0 0.12 0.1669 1.0 1852032 ChemDiv1_006980 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(cc3)[N+](=O)[O-])C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N07 compound treatment 690116.0 95900.0 0.43 666439.0 84200.0 0.42 0.5986 0.9999 1973610 ChemDiv1_006981 CCOc1ccc(cc1)N2C(=O)/C(=C/c3cc(CC=C)c(OCC(=O)O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N08 compound treatment 641837.0 47700.0 0.21 642192.0 60000.0 0.3 0.3609 0.9868 1852052 ChemDiv1_006982 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)Nc4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N09 compound treatment 662727.0 68600.0 0.31 660829.0 78600.0 0.39 0.4923 0.9931 1973611 ChemDiv1_006983 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc4OCOc4c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N10 compound treatment 638554.0 44400.0 0.2 649656.0 67400.0 0.33 0.3766 0.9692 1584625 ChemDiv1_006984 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N11 compound treatment 656798.0 62600.0 0.28 686087.0 104000.0 0.51 0.562 0.9592 1649216 ChemDiv1_006985 COc1cc(C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4)c(OC)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N12 compound treatment 644401.0 50200.0 0.22 649087.0 66800.0 0.33 0.3931 0.9822 1128379 ChemDiv1_006986 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccc(Br)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N13 compound treatment 660996.0 66800.0 0.3 686438.0 104000.0 0.52 0.5765 0.9663 1973612 ChemDiv1_006987 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccc(cc3)C(=O)C)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N14 compound treatment 637469.0 43300.0 0.19 596335.0 14100.0 0.07 0.1864 0.905 1546442 ChemDiv1_006988 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N15 compound treatment 659821.0 65600.0 0.29 670039.0 87800.0 0.43 0.5153 0.9818 1720250 ChemDiv1_006989 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N16 compound treatment 662972.0 68800.0 0.31 660110.0 77900.0 0.39 0.4905 0.9938 1426386 ChemDiv1_006990 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N17 compound treatment 674306.0 80100.0 0.36 704971.0 123000.0 0.61 0.6836 0.9683 1973613 ChemDiv1_006991 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N18 compound treatment 646851.0 52700.0 0.24 671074.0 88800.0 0.44 0.4779 0.9572 1309408 ChemDiv1_006992 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5ccc(Br)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N19 compound treatment 650479.0 56300.0 0.25 679951.0 97700.0 0.48 0.5205 0.9537 1623172 ChemDiv1_006993 Cc1ccc(COc2ccc(Br)cc2C=c3sc4nc5ccccc5n4c3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N20 compound treatment 658362.0 64200.0 0.29 652428.0 70200.0 0.35 0.449 0.9955 1652312 ChemDiv1_006994 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccsc3)C(=O)Nc4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N21 compound treatment 618088.0 23900.0 0.11 659514.0 77300.0 0.38 0.3464 0.8714 1538252 ChemDiv1_006995 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCCc4cc3C#N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N22 compound treatment 638943.0 44800.0 0.2 661023.0 78800.0 0.39 0.4177 0.952 1973614 ChemDiv1_006996 COc1ccc(OC)c(c1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N23 mock treatment 601413.0 7240.0 0.03 649284.0 67000.0 0.33 0.2578 0.7724 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 N24 mock treatment 459897.0 -134000.0 -0.6 455553.0 -127000.0 -0.63 -0.8688 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O01 compound treatment 611941.0 17800.0 0.08 608463.0 26200.0 0.13 0.1481 0.9723 1973615 ChemDiv1_006997 CCCCN(CCCC)S(=O)(=O)c1cccc2nonc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O02 compound treatment 832730.0 239000.0 1.07 825139.0 243000.0 1.2 1.6059 0.9982 1973616 ChemDiv1_006998 Brc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O03 compound treatment 615540.0 21400.0 0.1 659568.0 77300.0 0.38 0.3385 0.8573 1973617 ChemDiv1_006999 CCN(CC)c1cc(Nc2ccccc2OC)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O04 compound treatment 613474.0 19300.0 0.09 626150.0 43900.0 0.22 0.2149 0.9182 1973618 ChemDiv1_007000 CN1C(=O)C(=Cc2cc(C)n(c2C)c3ccc(C)c(c3)[N+](=O)[O-])C(=O)N(C)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O05 compound treatment 619958.0 25800.0 0.12 675193.0 93000.0 0.46 0.4072 0.8578 1973619 ChemDiv1_007001 Cc1ccc(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O06 compound treatment 625059.0 30900.0 0.14 636611.0 54400.0 0.27 0.2882 0.952 1973620 ChemDiv1_007002 Clc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O07 compound treatment 636208.0 42000.0 0.19 649704.0 67500.0 0.33 0.3694 0.9631 1973621 ChemDiv1_007003 CCN(c1ccccc1)c2cc(N(C)C)c3nonc3c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O08 compound treatment 641965.0 47800.0 0.21 664186.0 81900.0 0.41 0.4383 0.9552 1973622 ChemDiv1_007004 COc1ccc(cc1)C(=O)Oc2c(Cl)cc(C=C3C(=O)NC(=O)NC3=O)cc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O09 compound treatment 658574.0 64400.0 0.29 632355.0 50100.0 0.25 0.3794 0.9972 1973623 ChemDiv1_007005 CCOc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O10 compound treatment 652573.0 58400.0 0.26 665474.0 83200.0 0.41 0.4764 0.9758 1973624 ChemDiv1_007006 CCOc1cc(/C=C/2\SC(=N)NC2=O)ccc1OC(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O11 compound treatment 641428.0 47300.0 0.21 657403.0 75200.0 0.37 0.4129 0.9641 1973625 ChemDiv1_007007 [O-][N+](=O)c1c(Nc2ccc(Cl)cc2)cc(N3CCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O12 compound treatment 626512.0 32300.0 0.14 640363.0 58100.0 0.29 0.306 0.9494 1973626 ChemDiv1_007008 CCCCCSc1nc(N2CCOCC2)c3COC(C)(C)Cc3c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O13 compound treatment 650602.0 56400.0 0.25 675624.0 93400.0 0.46 0.5057 0.9595 1973627 ChemDiv1_007009 COc1ccccc1Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O14 compound treatment 668623.0 74400.0 0.33 671508.0 89300.0 0.44 0.5484 0.9903 1973628 ChemDiv1_007010 CCOC(=O)c1cccc(c1)n2c(C)cc(C=C3C(=O)N(C)C(=S)N(C)C3=O)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O15 compound treatment 693230.0 99100.0 0.44 694843.0 113000.0 0.56 0.708 0.9935 1378791 ChemDiv1_007011 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O16 compound treatment 648690.0 54500.0 0.24 652639.0 70400.0 0.35 0.4192 0.9847 1973629 ChemDiv1_007012 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O17 compound treatment 673802.0 79600.0 0.36 704349.0 122000.0 0.6 0.6798 0.9682 1973630 ChemDiv1_007013 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(OCC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O18 compound treatment 637347.0 43200.0 0.19 669951.0 87700.0 0.43 0.4439 0.9334 1973631 ChemDiv1_007014 CCOc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(Br)c3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O19 compound treatment 645319.0 51100.0 0.23 692543.0 110000.0 0.55 0.5483 0.9254 1973632 ChemDiv1_007015 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(cc3)C(=O)O)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O20 compound treatment 624278.0 30100.0 0.13 621744.0 39500.0 0.2 0.2337 0.9834 1192194 ChemDiv1_007016 COc1ccc2nc(SCC(=O)O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O21 compound treatment 663958.0 69800.0 0.31 674296.0 92100.0 0.46 0.5434 0.983 1973633 ChemDiv1_007017 Cc1c(NC(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O22 compound treatment 648900.0 54700.0 0.24 659825.0 77600.0 0.38 0.445 0.9763 1973634 ChemDiv1_007018 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3F)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O23 mock treatment 625955.0 31800.0 0.14 634948.0 52700.0 0.26 0.2852 0.9592 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 O24 mock treatment 513576.0 -80600.0 -0.36 530704.0 -51500.0 -0.26 -0.4356 -0.9857 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P01 compound treatment 560623.0 -33600.0 -0.15 550395.0 -31800.0 -0.16 -0.2177 -0.9997 1973635 ChemDiv1_007019 CC(Oc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)c(C)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P02 compound treatment 563706.0 -30500.0 -0.14 577765.0 -4470.0 -0.02 -0.1121 -0.8113 1160446 ChemDiv1_007020 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P03 compound treatment 594256.0 80.8 0.0 594575.0 12300.0 0.06 0.0435 0.7113 1973636 ChemDiv1_007021 Cc1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(C)cc3)c(C)n1c4cc(cc(c4)C(=O)O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P04 compound treatment 579045.0 -15100.0 -0.07 604601.0 22400.0 0.11 0.0304 0.2345 1388647 ChemDiv1_007022 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Br)c3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P05 compound treatment 594402.0 227.0 0.0 604151.0 21900.0 0.11 0.0775 0.7137 1973637 ChemDiv1_007023 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3)cc(CC=C)c1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P06 compound treatment 599648.0 5470.0 0.02 579211.0 -3030.0 -0.01 0.0067 0.2341 1556239 ChemDiv1_007024 CC1=C(C(C2=C(CCCC2=O)N1)c3ccccc3Cl)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P07 compound treatment 617158.0 23000.0 0.1 612889.0 30700.0 0.15 0.1801 0.982 1973638 ChemDiv1_007025 CC(Oc1ccc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Br)c3)cc1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P08 compound treatment 608207.0 14000.0 0.06 612457.0 30200.0 0.15 0.1503 0.9256 1696155 ChemDiv1_007026 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3C)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P09 compound treatment 672613.0 78400.0 0.35 658462.0 76200.0 0.38 0.5153 0.9993 1973639 ChemDiv1_007027 Cc1cc(C)cc(c1)N2C(=O)NC(=O)/C(=C\c3cc(Br)c(o3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P10 compound treatment 620477.0 26300.0 0.12 593912.0 11700.0 0.06 0.1241 0.9464 1125797 ChemDiv1_007028 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P11 compound treatment 589096.0 -5080.0 -0.02 613368.0 31100.0 0.15 0.093 0.5964 1304688 ChemDiv1_007029 COc1cc(C2Nc3cc(C)c(C)cc3NC4=C2C(=O)CC(C)(C)C4)c(Br)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P12 compound treatment 633239.0 39100.0 0.17 618004.0 35800.0 0.18 0.2489 1.0 1340949 ChemDiv1_007030 COc1cc(ccc1OCc2ccccc2)C3C(=C(C)NC4=C3C(=O)CCC4)C(=O)Nc5ccc(C)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P13 compound treatment 614948.0 20800.0 0.09 601510.0 19300.0 0.1 0.1333 0.9999 1668988 ChemDiv1_007031 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3C(=O)OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P14 compound treatment 612045.0 17900.0 0.08 596169.0 13900.0 0.07 0.1054 0.9973 1654466 ChemDiv1_007032 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(Br)cc3)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P15 compound treatment 609282.0 15100.0 0.07 616894.0 34700.0 0.17 0.1692 0.9171 1973640 ChemDiv1_007033 Cc1c(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P16 compound treatment 611018.0 16800.0 0.08 620524.0 38300.0 0.19 0.1874 0.9183 1713669 ChemDiv1_007034 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3cccc(Cl)c3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P17 compound treatment 654029.0 59900.0 0.27 657546.0 75300.0 0.37 0.4533 0.9868 1973641 ChemDiv1_007035 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(cc5)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P18 compound treatment 627295.0 33100.0 0.15 625031.0 42800.0 0.21 0.2547 0.9847 1614227 ChemDiv1_007036 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Oc4ccccc4)c3)C(=O)Nc5cccc(C)n5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P19 compound treatment 628705.0 34500.0 0.15 601780.0 19500.0 0.1 0.1778 0.9746 1973642 ChemDiv1_007037 Cc1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=S)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P20 compound treatment 602980.0 8800.0 0.04 625347.0 43100.0 0.21 0.1789 0.8237 1973643 ChemDiv1_007038 Cc1ccc(cc1)C(=O)C2=C(N)OC3=C(C2c4ccccc4Cl)C(=O)CCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P21 compound treatment 608417.0 14200.0 0.06 606795.0 24600.0 0.12 0.1311 0.9545 1349846 ChemDiv1_007039 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCCCc4cc3C#N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P22 compound treatment 597653.0 3480.0 0.02 603471.0 21200.0 0.11 0.0854 0.803 1973644 ChemDiv1_007040 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P23 mock treatment 607662.0 13500.0 0.06 585084.0 2850.0 0.01 0.0527 0.8494 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.606 P24 mock treatment 506128.0 -88000.0 -0.39 559414.0 -22800.0 -0.11 -0.3586 -0.8747 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A01 compound treatment 602890.0 37100.0 0.17 576468.0 3240.0 0.02 0.1287 0.7719 1973645 ChemDiv1_007041 COC(=O)C1=C(N)OC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A02 compound treatment 598915.0 33100.0 0.15 556860.0 -16400.0 -0.08 0.0475 0.2809 1536804 ChemDiv1_007042 COc1ccccc1C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A03 compound treatment 598491.0 32700.0 0.15 556870.0 -16400.0 -0.08 0.0461 0.2759 1973646 ChemDiv1_007043 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A04 compound treatment 601240.0 35400.0 0.16 564362.0 -8860.0 -0.04 0.0811 0.4928 1742982 ChemDiv1_007044 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A05 compound treatment 616449.0 50600.0 0.23 578063.0 4840.0 0.02 0.1772 0.7775 1973647 ChemDiv1_007045 COC(=O)C1=C(N)OC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A06 compound treatment 675443.0 110000.0 0.49 611208.0 38000.0 0.19 0.4801 0.9134 1288807 ChemDiv1_007046 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A07 compound treatment 650536.0 84700.0 0.38 597568.0 24300.0 0.12 0.3534 0.8881 1973648 ChemDiv1_007047 COC(=O)C1=C(N)OC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A08 compound treatment 674966.0 109000.0 0.49 613392.0 40200.0 0.2 0.4862 0.9216 1973649 ChemDiv1_007048 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A09 compound treatment 647089.0 81300.0 0.36 609898.0 36700.0 0.18 0.3857 0.9485 1973650 ChemDiv1_007049 COC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A10 compound treatment 653232.0 87400.0 0.39 612278.0 39100.0 0.19 0.4135 0.9472 1653667 ChemDiv1_007050 CC(=O)N1N=C(CC1c2cn(nc2c3ccc(C)cc3)c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A11 compound treatment 642179.0 76400.0 0.34 602735.0 29500.0 0.15 0.3451 0.9282 1973651 ChemDiv1_007051 CCOC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A12 compound treatment 673120.0 107000.0 0.48 614662.0 41400.0 0.21 0.4848 0.9281 1698924 ChemDiv1_007052 CCc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc5OCCOc5c4)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A13 compound treatment 703214.0 137000.0 0.62 626635.0 53400.0 0.26 0.622 0.929 1973652 ChemDiv1_007053 COc1cc(C=c2sc3nc4c(C)cccc4n3c2=O)cc(Br)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A14 compound treatment 664255.0 98400.0 0.44 607846.0 34600.0 0.17 0.4329 0.9154 1973653 ChemDiv1_007054 Cc1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A15 compound treatment 694633.0 129000.0 0.58 614854.0 41600.0 0.21 0.5536 0.9039 1973654 ChemDiv1_007055 COc1ccc(cc1OC)N(CC(=O)Nc2ccccc2Br)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A16 compound treatment 682607.0 117000.0 0.52 593674.0 20400.0 0.1 0.4413 0.8287 1973655 ChemDiv1_007056 Cc1ccc2n(CC(=O)Nc3ccc(cc3)C(F)(F)F)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A17 compound treatment 676220.0 110000.0 0.49 594066.0 20800.0 0.1 0.4225 0.8368 1225499 ChemDiv1_007057 COC(=O)c1ccccc1NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A18 compound treatment 660657.0 94800.0 0.42 590419.0 17200.0 0.09 0.3604 0.8324 1973656 ChemDiv1_007058 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(F)cc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A19 compound treatment 646660.0 80800.0 0.36 603738.0 30500.0 0.15 0.3628 0.925 1973657 ChemDiv1_007059 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(C)c(c3)[N+](=O)[O-])/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A20 compound treatment 625927.0 60100.0 0.27 586882.0 13700.0 0.07 0.2381 0.8582 1973658 ChemDiv1_007060 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(Cl)c(C)c4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A21 compound treatment 642073.0 76300.0 0.34 601656.0 28400.0 0.14 0.341 0.9233 1973659 ChemDiv1_007061 [O-][N+](=O)c1cc(/C=C/2\SC(=N)N(C2=O)c3ccc(F)cc3)c(cc1N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A22 compound treatment 616485.0 50700.0 0.23 582942.0 9720.0 0.05 0.1944 0.8385 1327438 ChemDiv1_007062 Fc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4Cl)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A23 mock treatment 645652.0 79800.0 0.36 570276.0 -2950.0 -0.01 0.2424 0.6776 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 A24 mock treatment 521361.0 -44500.0 -0.2 482405.0 -90800.0 -0.45 -0.4588 -0.9327 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B01 compound treatment 599481.0 33700.0 0.15 590069.0 16800.0 0.08 0.1656 0.9611 1973660 ChemDiv1_007063 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B02 compound treatment 670790.0 105000.0 0.47 646344.0 73100.0 0.36 0.5884 0.9917 1496615 ChemDiv1_007064 Clc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B03 compound treatment 677411.0 112000.0 0.5 646616.0 73400.0 0.36 0.6103 0.9878 1699976 ChemDiv1_007065 COc1ccc(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B04 compound treatment 679028.0 113000.0 0.51 631424.0 58200.0 0.29 0.5622 0.9643 1583855 ChemDiv1_007066 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B05 compound treatment 705652.0 140000.0 0.63 662558.0 89300.0 0.44 0.7555 0.9856 1335280 ChemDiv1_007067 Cc1ccc(cc1)c2csc(NC(=O)N3CCOCC3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B06 compound treatment 698616.0 133000.0 0.59 652062.0 78800.0 0.39 0.6965 0.9792 1185860 ChemDiv1_007068 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B07 compound treatment 705287.0 139000.0 0.62 672749.0 99500.0 0.49 0.7901 0.9932 1927002 ChemDiv1_007069 O=C1Nc2ccccc2C13C4=C(NC5=C3C(=O)c6ccccc56)c7ccccc7C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B08 compound treatment 719814.0 154000.0 0.69 656400.0 83200.0 0.41 0.7788 0.9697 1519708 ChemDiv1_007070 CC(C)CC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B09 compound treatment 731377.0 166000.0 0.74 685254.0 112000.0 0.55 0.9165 0.9898 1973661 ChemDiv1_007071 CCCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B10 compound treatment 712652.0 147000.0 0.66 663478.0 90300.0 0.45 0.7809 0.9824 1402828 ChemDiv1_007072 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Br)cc3F)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B11 compound treatment 735425.0 170000.0 0.76 691026.0 118000.0 0.58 0.9495 0.9915 1973662 ChemDiv1_007073 CC(C)C1=CC23CCC4C(C)(CCCC4(C)C3CC1C5C2C(=O)N(CCO)C5=O)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B12 compound treatment 704838.0 139000.0 0.62 671079.0 97900.0 0.48 0.7828 0.9924 1973663 ChemDiv1_007074 COc1ccc(Oc2c(oc3cc(OC(C)C(=O)OC(C)C)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B13 compound treatment 740800.0 175000.0 0.78 684758.0 112000.0 0.55 0.9446 0.9854 1305650 ChemDiv1_007075 COc1cccc2c(C)nc(Nc3nc(O)c4ccccc4n3)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B14 compound treatment 740982.0 175000.0 0.78 646400.0 73200.0 0.36 0.8108 0.9386 1660710 ChemDiv1_007076 CC(C)COC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B15 compound treatment 766799.0 201000.0 0.9 694248.0 121000.0 0.6 1.0601 0.9805 1657301 ChemDiv1_007077 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)cc4OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B16 compound treatment 741004.0 175000.0 0.78 683967.0 111000.0 0.55 0.9424 0.9847 1481833 ChemDiv1_007078 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B17 compound treatment 765418.0 200000.0 0.89 693734.0 121000.0 0.6 1.0539 0.9808 1490349 ChemDiv1_007079 Cc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B18 compound treatment 723712.0 158000.0 0.71 668296.0 95100.0 0.47 0.8328 0.9805 1973664 ChemDiv1_007080 CCCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B19 compound treatment 738057.0 172000.0 0.77 676998.0 104000.0 0.51 0.9087 0.9806 1669068 ChemDiv1_007081 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)s3)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B20 compound treatment 682790.0 117000.0 0.52 664965.0 91700.0 0.45 0.6916 0.9975 1973665 ChemDiv1_007082 CCOC(=O)CSc1ncn[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B21 compound treatment 709268.0 143000.0 0.64 696962.0 124000.0 0.61 0.8875 0.9997 1725241 ChemDiv1_007083 CCC(C)OC(=O)C1=C(C)NC(=O)NC1c2ccc(OC)c(OCc3ccccc3)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B22 compound treatment 674711.0 109000.0 0.49 666108.0 92900.0 0.46 0.67 0.9996 1973666 ChemDiv1_007084 Cc1nnc(NC(=O)CCN2C(=O)/C(=C/c3cccc(Br)c3)/SC2=S)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B23 mock treatment 632895.0 67100.0 0.3 635881.0 62700.0 0.31 0.4318 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 B24 mock treatment 518063.0 -47800.0 -0.21 261198.0 -312000.0 -1.55 -1.2441 -0.7973 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C01 compound treatment 614634.0 48800.0 0.22 552393.0 -20800.0 -0.1 0.0816 0.3375 1973667 ChemDiv1_007085 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C02 compound treatment 654894.0 89100.0 0.4 588055.0 14800.0 0.07 0.3339 0.8235 1214561 ChemDiv1_007086 Cc1ccc(cc1)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C03 compound treatment 685259.0 119000.0 0.53 637238.0 64000.0 0.32 0.6023 0.9689 1973668 ChemDiv1_007087 COC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C04 compound treatment 683443.0 118000.0 0.53 627539.0 54300.0 0.27 0.5626 0.9514 1194008 ChemDiv1_007088 Cc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C05 compound treatment 708252.0 142000.0 0.64 622470.0 49200.0 0.24 0.6234 0.9131 1973669 ChemDiv1_007089 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C06 compound treatment 758635.0 193000.0 0.86 677102.0 104000.0 0.51 0.9742 0.9695 1575177 ChemDiv1_007090 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Br)cc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C07 compound treatment 730027.0 164000.0 0.74 640653.0 67400.0 0.33 0.756 0.9363 1973670 ChemDiv1_007091 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C08 compound treatment 731865.0 166000.0 0.74 670337.0 97100.0 0.48 0.8658 0.9778 1186824 ChemDiv1_007092 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C09 compound treatment 730115.0 164000.0 0.74 660928.0 87700.0 0.43 0.8273 0.9685 1973671 ChemDiv1_007093 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C10 compound treatment 751124.0 185000.0 0.83 647619.0 74400.0 0.37 0.8472 0.9333 1245121 ChemDiv1_007094 CC(=O)N1N=C(CC1c2cn(nc2c3ccc(C)cc3)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C11 compound treatment 741437.0 176000.0 0.79 680565.0 107000.0 0.53 0.9319 0.9819 1973672 ChemDiv1_007095 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C12 compound treatment 721564.0 156000.0 0.7 646990.0 73800.0 0.37 0.7514 0.9546 1333452 ChemDiv1_007096 Fc1ccc(cc1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C13 compound treatment 739409.0 174000.0 0.78 645924.0 72700.0 0.36 0.8041 0.9389 1973673 ChemDiv1_007097 CC(=O)CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C14 compound treatment 732854.0 167000.0 0.75 684325.0 111000.0 0.55 0.9179 0.9886 1973674 ChemDiv1_007098 Cc1ccc2n(CC(=O)Nc3ccc(OC(F)(F)F)cc3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C15 compound treatment 764303.0 198000.0 0.89 714273.0 141000.0 0.7 1.1223 0.9929 1697867 ChemDiv1_007099 CCOc1ccc(cc1)N(CC(=O)Nc2cc(OC)ccc2OC)S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C16 compound treatment 738243.0 172000.0 0.77 665024.0 91800.0 0.45 0.8673 0.9682 1973675 ChemDiv1_007100 Cc1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C17 compound treatment 758850.0 193000.0 0.86 720007.0 147000.0 0.73 1.1252 0.9963 1195754 ChemDiv1_007101 CCOC(=O)c1ccccc1NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C18 compound treatment 693659.0 128000.0 0.57 665167.0 91900.0 0.46 0.7267 0.9936 1973676 ChemDiv1_007102 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4F)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C19 compound treatment 1176714.0 611000.0 2.73 1138929.0 566000.0 2.8 3.9153 0.9999 1973677 ChemDiv1_007103 Cc1ccc(cc1Cl)N2C(=N)S/C(=C\c3ccccc3OCC(=O)O)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C20 compound treatment 687701.0 122000.0 0.55 662794.0 89600.0 0.44 0.6996 0.9947 1973678 ChemDiv1_007104 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccc(F)cc4)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C21 compound treatment 754661.0 189000.0 0.85 721326.0 148000.0 0.73 1.1165 0.9975 1973679 ChemDiv1_007105 CCC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3ccccc3F)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C22 compound treatment 671172.0 105000.0 0.47 642672.0 69400.0 0.34 0.5768 0.988 1266308 ChemDiv1_007106 COc1ccc(cc1OC)c2nc(Nc3ccc4OCCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C23 mock treatment 652790.0 87000.0 0.39 651098.0 77900.0 0.39 0.5481 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 C24 mock treatment 507897.0 -57900.0 -0.26 507635.0 -65600.0 -0.32 -0.4131 -0.9937 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D01 compound treatment 587121.0 21300.0 0.1 571272.0 -1950.0 -0.01 0.0606 0.6321 1973680 ChemDiv1_007107 COc1ccc(N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D02 compound treatment 638418.0 72600.0 0.33 612457.0 39200.0 0.19 0.3672 0.9698 1263212 ChemDiv1_007108 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D03 compound treatment 693454.0 128000.0 0.57 645444.0 72200.0 0.36 0.657 0.9746 1285012 ChemDiv1_007109 CCOc1ccc(cc1)N(CC(=O)Nc2ccccc2C(=O)OC)S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D04 compound treatment 650681.0 84900.0 0.38 650059.0 76800.0 0.38 0.5378 1.0 1973681 ChemDiv1_007110 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cccc(c2)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D05 compound treatment 702206.0 136000.0 0.61 664081.0 90900.0 0.45 0.75 0.9887 1500037 ChemDiv1_007111 N#CCn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D06 compound treatment 685859.0 120000.0 0.54 643885.0 70700.0 0.35 0.6275 0.9784 1576504 ChemDiv1_007112 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(Br)cc3)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D07 compound treatment 669361.0 104000.0 0.46 639531.0 66300.0 0.33 0.56 0.9858 1375317 ChemDiv1_007113 COc1cccc(Nc2nc(Cl)nc(Nc3cccc(OC)c3)n2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D08 compound treatment 711665.0 146000.0 0.65 671336.0 98100.0 0.49 0.8053 0.9894 1973682 ChemDiv1_007114 CCCCC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D09 compound treatment 740425.0 175000.0 0.78 669435.0 96200.0 0.48 0.8897 0.9719 1458209 ChemDiv1_007115 CCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D10 compound treatment 705162.0 139000.0 0.62 693873.0 121000.0 0.6 0.8637 0.9998 1973683 ChemDiv1_007116 CCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D11 compound treatment 759097.0 193000.0 0.87 725819.0 153000.0 0.76 1.1463 0.9977 1784333 ChemDiv1_007117 O=C(Nc1ccc(cc1)N2C(=O)C3CC=CCC3C2=O)c4ccc(cc4)N5C(=O)C6CC=CCC6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D12 compound treatment 702943.0 137000.0 0.61 671382.0 98200.0 0.49 0.7779 0.9933 1973684 ChemDiv1_007118 CCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D13 compound treatment 749053.0 183000.0 0.82 702216.0 129000.0 0.64 1.0318 0.9924 1253470 ChemDiv1_007119 Cc1cccc2c(C)nc(Nc3nc(=O)cc([nH]3)c4ccccc4)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D14 compound treatment 744044.0 178000.0 0.8 706945.0 134000.0 0.66 1.0326 0.9957 1422421 ChemDiv1_007120 Brc1ccccc1Oc2coc3cc(OCC(=O)OCc4ccccc4)ccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D15 compound treatment 765037.0 199000.0 0.89 736732.0 164000.0 0.81 1.2033 0.9988 1479986 ChemDiv1_007121 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D16 compound treatment 852991.0 287000.0 1.29 802938.0 230000.0 1.14 1.7137 0.9982 1973685 ChemDiv1_007122 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D17 compound treatment 760154.0 194000.0 0.87 704133.0 131000.0 0.65 1.0737 0.9895 1973686 ChemDiv1_007123 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccncc2)c3ccc(Cl)c(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D18 compound treatment 701746.0 136000.0 0.61 684239.0 111000.0 0.55 0.8191 0.9987 1973687 ChemDiv1_007124 CCOCCOC(=O)COc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D19 compound treatment 746896.0 181000.0 0.81 731765.0 159000.0 0.79 1.1285 0.9999 1312383 ChemDiv1_007125 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4n(C)c(=O)n(C)c4c3)c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D20 compound treatment 692827.0 127000.0 0.57 685113.0 112000.0 0.55 0.794 0.9999 1973688 ChemDiv1_007126 COCCOC(=O)CSc1ncn[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D21 compound treatment 714300.0 148000.0 0.66 719257.0 146000.0 0.72 0.9815 0.9991 1973689 ChemDiv1_007127 CCOC(=O)C1=CN(C=C(C1c2ccc(OC)c(Br)c2)C(=O)OCC)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D22 compound treatment 691318.0 126000.0 0.56 696317.0 123000.0 0.61 0.8284 0.9992 1973690 ChemDiv1_007128 CCOC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C\C(=C\c3ccccc3)\C)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D23 mock treatment 656195.0 90400.0 0.4 669663.0 96400.0 0.48 0.6239 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 D24 mock treatment 524850.0 -41000.0 -0.18 528773.0 -44500.0 -0.22 -0.2854 -0.9959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E01 compound treatment 616650.0 50800.0 0.23 556170.0 -17100.0 -0.08 0.1012 0.4168 1973691 ChemDiv1_007129 CCOC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E02 compound treatment 666080.0 100000.0 0.45 605858.0 32600.0 0.16 0.4317 0.9049 1923834 ChemDiv1_007130 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E03 compound treatment 703645.0 138000.0 0.62 637234.0 64000.0 0.32 0.6605 0.9521 1973692 ChemDiv1_007131 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E04 compound treatment 691566.0 126000.0 0.56 627682.0 54500.0 0.27 0.5888 0.9433 1973693 ChemDiv1_007132 CC(=O)N1N=C(CC1c2ccc(cc2)[N+](=O)[O-])c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E05 compound treatment 706060.0 140000.0 0.63 653453.0 80200.0 0.4 0.7249 0.9757 1973694 ChemDiv1_007133 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E06 compound treatment 748419.0 183000.0 0.82 696518.0 123000.0 0.61 1.0099 0.9897 1973695 ChemDiv1_007134 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E07 compound treatment 738198.0 172000.0 0.77 664502.0 91300.0 0.45 0.8654 0.9676 1973696 ChemDiv1_007135 COC(=O)C1=C(N)OC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E08 compound treatment 777132.0 211000.0 0.95 712279.0 139000.0 0.69 1.156 0.9879 1973697 ChemDiv1_007136 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E09 compound treatment 763408.0 198000.0 0.88 689894.0 117000.0 0.58 1.0341 0.9787 1973698 ChemDiv1_007137 COC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E10 compound treatment 735962.0 170000.0 0.76 683080.0 110000.0 0.54 0.9234 0.9864 1973699 ChemDiv1_007138 Brc1ccc(OCc2ccccc2)c(C=C3C(=O)NC(=O)NC3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E11 compound treatment 739567.0 174000.0 0.78 710669.0 137000.0 0.68 1.0314 0.9978 1973700 ChemDiv1_007139 CCOC(=O)C1=C(N)OC2=C(C1c3ccsc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E12 compound treatment 749478.0 184000.0 0.82 682858.0 110000.0 0.54 0.9654 0.9797 1240277 ChemDiv1_007140 Clc1cccc(c1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E13 compound treatment 734355.0 169000.0 0.75 704021.0 131000.0 0.65 0.9916 0.9971 1600172 ChemDiv1_007141 O=C(CSc1nc2ccc(Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5)cc2s1)NCC6CCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E14 compound treatment 734043.0 168000.0 0.75 690373.0 117000.0 0.58 0.9428 0.9917 1973701 ChemDiv1_007142 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E15 compound treatment 787273.0 221000.0 0.99 738249.0 165000.0 0.82 1.279 0.9954 1484052 ChemDiv1_007143 CCOc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E16 compound treatment 769300.0 203000.0 0.91 708128.0 135000.0 0.67 1.1166 0.9884 1973702 ChemDiv1_007144 Clc1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E17 compound treatment 774755.0 209000.0 0.94 701415.0 128000.0 0.64 1.1104 0.9822 1973703 ChemDiv1_007145 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E18 compound treatment 754506.0 189000.0 0.84 685658.0 112000.0 0.56 0.9911 0.9796 1973704 ChemDiv1_007146 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E19 compound treatment 898912.0 333000.0 1.49 863497.0 290000.0 1.44 2.0711 0.9998 1973705 ChemDiv1_007147 Brc1ccc(OCC=C)c(/C=C/2\Sc3ccccc3C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E20 compound treatment 731527.0 166000.0 0.74 683308.0 110000.0 0.55 0.9101 0.9885 1123926 ChemDiv1_007148 CCOC(=O)c1nc(Nc2cccc(Cl)c2C)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E21 compound treatment 736715.0 171000.0 0.77 685341.0 112000.0 0.56 0.9337 0.9876 1973706 ChemDiv1_007149 Cn1c(nc2ccccc12)c3nonc3NC(=O)CSc4nc5ccccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E22 compound treatment 660336.0 94500.0 0.42 671340.0 98100.0 0.49 0.6429 0.9976 1973707 ChemDiv1_007150 CCOC(=O)c1nc(Nc2ccc(cc2)C(F)(F)F)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E23 mock treatment 681608.0 116000.0 0.52 675794.0 103000.0 0.51 0.7258 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 E24 mock treatment 537508.0 -28300.0 -0.13 522264.0 -51000.0 -0.25 -0.2681 -0.9492 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F01 compound treatment 605166.0 39400.0 0.18 571029.0 -2200.0 -0.01 0.1169 0.6622 1973708 ChemDiv1_007151 COc1ccc(CCNC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F02 compound treatment 830351.0 265000.0 1.18 792250.0 219000.0 1.09 1.6045 0.999 1973709 ChemDiv1_007152 O=C(NCCSCc1ccccc1)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F03 compound treatment 692161.0 126000.0 0.57 638262.0 65000.0 0.32 0.6277 0.9644 1393797 ChemDiv1_007153 Clc1ccc(cc1)C(=O)Nc2nc3cc(NC(=O)c4ccc(Cl)cc4)ccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F04 compound treatment 685697.0 120000.0 0.54 650707.0 77500.0 0.38 0.6509 0.9865 1613452 ChemDiv1_007154 Clc1ccc(cc1Cl)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F05 compound treatment 700574.0 135000.0 0.6 673825.0 101000.0 0.5 0.7789 0.9955 1724714 ChemDiv1_007155 OCCNC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F06 compound treatment 697203.0 131000.0 0.59 673534.0 100000.0 0.5 0.7673 0.9965 1973710 ChemDiv1_007156 Clc1cccc(N(CC(=O)NCCSc2ccccn2)S(=O)(=O)c3ccccc3)c1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F07 compound treatment 704138.0 138000.0 0.62 669143.0 95900.0 0.48 0.7738 0.9914 1925757 ChemDiv1_007157 COc1ccc2N(C(=O)CSc3ncn[nH]3)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F08 compound treatment 718618.0 153000.0 0.68 664808.0 91600.0 0.45 0.8045 0.9801 1973711 ChemDiv1_007158 OC(=O)CCCNC(=O)c1ccc2OCCOc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F09 compound treatment 867994.0 302000.0 1.35 793188.0 220000.0 1.09 1.727 0.9943 1973712 ChemDiv1_007159 Cc1ccc(cc1)C(=O)N2N=C(CC2c3ccco3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F10 compound treatment 667260.0 101000.0 0.45 652843.0 79600.0 0.39 0.6 0.9975 1973713 ChemDiv1_007160 CCCOC(=O)COc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F11 compound treatment 700255.0 134000.0 0.6 713137.0 140000.0 0.69 0.9156 0.9975 1541003 ChemDiv1_007161 COC(=O)c1ccccc1NC(=O)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F12 compound treatment 681835.0 116000.0 0.52 669324.0 96100.0 0.48 0.7039 0.9991 1973714 ChemDiv1_007162 CCCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F13 compound treatment 747892.0 182000.0 0.82 683618.0 110000.0 0.55 0.963 0.9812 1973715 ChemDiv1_007163 Cc1ccc2nc(NC3=NC(CC(=O)N3)c4ccccc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F14 compound treatment 745972.0 180000.0 0.81 699224.0 126000.0 0.62 1.0116 0.992 1133404 ChemDiv1_007164 Brc1ccccc1Oc2coc3cc(OCC(=O)OC4CCCCC4)ccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F15 compound treatment 756470.0 191000.0 0.85 723061.0 150000.0 0.74 1.1283 0.9976 1160743 ChemDiv1_007165 Cc1c(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F16 compound treatment 747706.0 182000.0 0.81 725459.0 152000.0 0.75 1.109 0.9993 1505434 ChemDiv1_007166 Cc1cc(C)cc(Oc2coc3cc(OCC(=O)OCc4ccccc4)ccc3c2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F17 compound treatment 756915.0 191000.0 0.86 734836.0 162000.0 0.8 1.171 0.9995 1384618 ChemDiv1_007167 COc1ccc(C)cc1N(CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F18 compound treatment 741562.0 176000.0 0.79 682090.0 109000.0 0.54 0.9376 0.983 1973716 ChemDiv1_007168 COc1ccc(cc1OC)c2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F19 compound treatment 724746.0 159000.0 0.71 698936.0 126000.0 0.62 0.9434 0.9978 1973717 ChemDiv1_007169 CN1C(=O)N(C)C(=O)C(=Cc2cn(Cc3ccccc3C#N)c4ccccc24)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F20 compound treatment 704081.0 138000.0 0.62 688010.0 115000.0 0.57 0.8397 0.9991 1973718 ChemDiv1_007170 CN(C)CCOC(=O)CCN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F21 compound treatment 720249.0 154000.0 0.69 702590.0 129000.0 0.64 0.942 0.9993 1973719 ChemDiv1_007171 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)ccc2OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F22 compound treatment 684433.0 119000.0 0.53 692639.0 119000.0 0.59 0.7938 0.9985 1973720 ChemDiv1_007172 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(CCC(=O)N3CCCc4ccccc34)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F23 mock treatment 661377.0 95600.0 0.43 669306.0 96100.0 0.48 0.639 0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 F24 mock treatment 513327.0 -52500.0 -0.23 516942.0 -56300.0 -0.28 -0.3633 -0.9964 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G01 compound treatment 592748.0 26900.0 0.12 559524.0 -13700.0 -0.07 0.0373 0.2693 1973721 ChemDiv1_007173 COC(=O)C1=C(N)OC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G02 compound treatment 661541.0 95700.0 0.43 614149.0 40900.0 0.2 0.4464 0.9416 1925508 ChemDiv1_007174 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G03 compound treatment 701608.0 136000.0 0.61 656633.0 83400.0 0.41 0.722 0.9823 1973722 ChemDiv1_007175 CCOC(=O)C1=C(N)OC2=C(C1c3cc(ccc3Cl)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G04 compound treatment 698480.0 133000.0 0.59 653608.0 80400.0 0.4 0.7015 0.9811 1973723 ChemDiv1_007176 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G05 compound treatment 716271.0 150000.0 0.67 670608.0 97400.0 0.48 0.8174 0.9866 1973724 ChemDiv1_007177 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(C)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G06 compound treatment 709570.0 144000.0 0.64 686097.0 113000.0 0.56 0.8504 0.9975 1784109 ChemDiv1_007178 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G07 compound treatment 748129.0 182000.0 0.82 663670.0 90400.0 0.45 0.8939 0.9601 1973725 ChemDiv1_007179 COc1ccc(C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G08 compound treatment 728686.0 163000.0 0.73 687823.0 115000.0 0.57 0.917 0.9923 1128692 ChemDiv1_007180 CC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G09 compound treatment 750422.0 185000.0 0.83 680748.0 108000.0 0.53 0.961 0.9774 1383904 ChemDiv1_007181 CCOC(=O)C1=C(N)OC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G10 compound treatment 739284.0 173000.0 0.78 658429.0 85200.0 0.42 0.8475 0.959 1973726 ChemDiv1_007182 Brc1ccc(cc1)C(=O)NC(=S)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G11 compound treatment 741198.0 175000.0 0.79 710977.0 138000.0 0.68 1.0377 0.9976 1866051 ChemDiv1_007183 COc1ccc2oc(=O)c(cc2c1)C(=O)N3CCN(C/C=C/c4ccccc4)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G12 compound treatment 711223.0 145000.0 0.65 680892.0 108000.0 0.53 0.8374 0.9951 1477833 ChemDiv1_007184 Brc1cccc(c1)c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G13 compound treatment 798129.0 232000.0 1.04 716958.0 144000.0 0.71 1.2388 0.9829 1474623 ChemDiv1_007185 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cccc(c2)c3nc4ccc(C)cc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G14 compound treatment 758296.0 192000.0 0.86 695644.0 122000.0 0.61 1.0381 0.9852 1973727 ChemDiv1_007186 COc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G15 compound treatment 793318.0 228000.0 1.02 754489.0 181000.0 0.9 1.3551 0.998 1973728 ChemDiv1_007187 COc1ccc(Cl)cc1N(CC(=O)N2CCc3ccccc3C2)S(=O)(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G16 compound treatment 742036.0 176000.0 0.79 706500.0 133000.0 0.66 1.0246 0.9961 1578354 ChemDiv1_007188 CCOC(=O)c1nc(Nc2ccc(Cl)cc2C)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G17 compound treatment 1934459.0 1370000.0 6.13 1723889.0 1150000.0 5.7 8.3628 0.9994 1077754 ChemDiv1_007189 COC1C(CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G18 compound treatment 734841.0 169000.0 0.76 695138.0 122000.0 0.6 0.9621 0.9938 1973729 ChemDiv1_007190 Cc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G19 compound treatment 759543.0 194000.0 0.87 736901.0 164000.0 0.81 1.1865 0.9994 1422550 ChemDiv1_007191 COc1ccc2cc(C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5)c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G20 compound treatment 693784.0 128000.0 0.57 692440.0 119000.0 0.59 0.8227 0.9999 1198963 ChemDiv1_007192 CCOC(=O)c1nc(Nc2ccc(F)c(Cl)c2)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G21 compound treatment 733690.0 168000.0 0.75 691022.0 118000.0 0.58 0.944 0.9922 1661941 ChemDiv1_007193 Cc1cc(O)c(NC(=O)c2ccc3OCCOc3c2)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G22 compound treatment 677873.0 112000.0 0.5 687495.0 114000.0 0.57 0.755 0.9982 1973730 ChemDiv1_007194 [O-][N+](=O)c1ccc2nc(Cc3ccc(Cl)c(c3)[N+](=O)[O-])c(=O)[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G23 mock treatment 687157.0 121000.0 0.54 683588.0 110000.0 0.55 0.7707 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 G24 mock treatment 541775.0 -24000.0 -0.11 525378.0 -47800.0 -0.24 -0.2437 -0.9362 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H01 compound treatment 607307.0 41500.0 0.19 569757.0 -3470.0 -0.02 0.1192 0.639 1155020 ChemDiv1_007195 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(OC)cc2OC)S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H02 compound treatment 656717.0 90900.0 0.41 604737.0 31500.0 0.16 0.3981 0.9135 1275324 ChemDiv1_007196 Cc1c(NC(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H03 compound treatment 826616.0 261000.0 1.17 752148.0 179000.0 0.89 1.4523 0.9908 1973731 ChemDiv1_007197 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCc3ccccn3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H04 compound treatment 688643.0 123000.0 0.55 637807.0 64600.0 0.32 0.615 0.9668 1574991 ChemDiv1_007198 Cc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H05 compound treatment 827829.0 262000.0 1.17 747069.0 174000.0 0.86 1.4383 0.9885 1973732 ChemDiv1_007199 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H06 compound treatment 679377.0 114000.0 0.51 640670.0 67400.0 0.33 0.5957 0.9793 1973733 ChemDiv1_007200 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H07 compound treatment 708024.0 142000.0 0.64 671378.0 98200.0 0.49 0.794 0.9912 1973734 ChemDiv1_007201 COc1ccc(cc1)C2=NN(C(C2)c3ccc(Cl)cc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H08 compound treatment 701251.0 135000.0 0.61 668230.0 95000.0 0.47 0.7615 0.9922 1727639 ChemDiv1_007202 O=C(Nc1ccc2oc(nc2c1)c3cccnc3)c4cccc(OCc5ccccc5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H09 compound treatment 709049.0 143000.0 0.64 668291.0 95100.0 0.47 0.7864 0.9885 1973735 ChemDiv1_007203 O=C(CSc1ncn(n1)c2ccccc2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H10 compound treatment 713284.0 147000.0 0.66 674900.0 102000.0 0.5 0.8229 0.9911 1973736 ChemDiv1_007204 CC(C)OC(=O)COc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H11 compound treatment 743511.0 178000.0 0.8 666462.0 93200.0 0.46 0.8891 0.9666 1117660 ChemDiv1_007205 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N=c3ssc4c3-c5ccccc5NC4(C)C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H12 compound treatment 689466.0 124000.0 0.55 653178.0 80000.0 0.4 0.6715 0.9865 1973737 ChemDiv1_007206 COc1ccc(Oc2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H13 compound treatment 735060.0 169000.0 0.76 690516.0 117000.0 0.58 0.9466 0.9914 1427026 ChemDiv1_007207 COc1ccc(NC2CC(C)N(C(=O)c3ccccc3)c4ccc(OC)cc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H14 compound treatment 722964.0 157000.0 0.7 696157.0 123000.0 0.61 0.928 0.9974 1196575 ChemDiv1_007208 CCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H15 compound treatment 738504.0 173000.0 0.77 692439.0 119000.0 0.59 0.9642 0.9912 1461196 ChemDiv1_007209 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(OC)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H16 compound treatment 693624.0 128000.0 0.57 683337.0 110000.0 0.55 0.7903 0.9997 1973738 ChemDiv1_007210 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cc(C)cc(C)c3)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H17 compound treatment 738294.0 172000.0 0.77 721272.0 148000.0 0.73 1.0645 0.9997 1239430 ChemDiv1_007211 CS(=O)(=O)N(CC(=O)N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H18 compound treatment 693220.0 127000.0 0.57 680306.0 107000.0 0.53 0.7784 0.9993 1973739 ChemDiv1_007212 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(OC)c(OC)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H19 compound treatment 762466.0 197000.0 0.88 729939.0 157000.0 0.78 1.1714 0.998 1191409 ChemDiv1_007213 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(o3)N4CCOCC4)c(=O)n2C1c5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H20 compound treatment 695770.0 130000.0 0.58 683313.0 110000.0 0.55 0.797 0.9995 1973740 ChemDiv1_007214 OC(=O)c1ccccc1NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H21 compound treatment 723392.0 158000.0 0.71 699503.0 126000.0 0.63 0.9411 0.9982 1298106 ChemDiv1_007215 COc1ccc(cc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OCC4CCCO4)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H22 compound treatment 727966.0 162000.0 0.73 719975.0 147000.0 0.73 1.0273 1.0 1973741 ChemDiv1_007216 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(CCC(=O)NCCCN3CCOCC3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H23 mock treatment 650773.0 85000.0 0.38 661041.0 87800.0 0.44 0.5765 0.9978 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 H24 mock treatment 262339.0 -303000.0 -1.36 541201.0 -32000.0 -0.16 -1.0728 -0.7844 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I01 compound treatment 596737.0 30900.0 0.14 551304.0 -21900.0 -0.11 0.0211 0.1199 1973742 ChemDiv1_007217 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I02 compound treatment 658888.0 93100.0 0.42 605413.0 32200.0 0.16 0.4074 0.9131 1410569 ChemDiv1_007218 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I03 compound treatment 686551.0 121000.0 0.54 645315.0 72100.0 0.36 0.6347 0.9798 1973743 ChemDiv1_007219 COC(=O)C1=C(N)OC2=C(C1c3cc(ccc3Cl)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I04 compound treatment 702641.0 137000.0 0.61 637082.0 63900.0 0.32 0.6568 0.9527 1973744 ChemDiv1_007220 Cc1ccc(cc1)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I05 compound treatment 722796.0 157000.0 0.7 654366.0 81100.0 0.4 0.7811 0.9649 1973745 ChemDiv1_007221 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I06 compound treatment 719685.0 154000.0 0.69 636280.0 63100.0 0.31 0.7079 0.936 1973746 ChemDiv1_007222 OC(=O)CCC(=O)N1N=C(CC1c2ccc(cc2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Br)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I07 compound treatment 740101.0 174000.0 0.78 683328.0 110000.0 0.55 0.9373 0.9847 1973747 ChemDiv1_007223 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I08 compound treatment 781869.0 216000.0 0.97 747515.0 174000.0 0.86 1.2944 0.9984 1554236 ChemDiv1_007224 OC(=O)CCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I09 compound treatment 744608.0 179000.0 0.8 681604.0 108000.0 0.54 0.9456 0.9811 1973748 ChemDiv1_007225 COC(=O)C1=C(N)OC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I10 compound treatment 737825.0 172000.0 0.77 648708.0 75500.0 0.37 0.8089 0.945 1557935 ChemDiv1_007226 CCOc1ccc(Nc2nc(NCc3cccnc3)nc(OC)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I11 compound treatment 755162.0 189000.0 0.85 701017.0 128000.0 0.63 1.047 0.9897 1973749 ChemDiv1_007227 Cc1ccc(NC(=O)c2cc3cc(Br)ccc3oc2=O)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I12 compound treatment 728516.0 163000.0 0.73 691392.0 118000.0 0.59 0.9289 0.9941 1398368 ChemDiv1_007228 Brc1ccccc1c2nc3cc(NC(=O)c4ccc5OCCOc5c4)ccc3o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I13 compound treatment 757629.0 192000.0 0.86 694672.0 121000.0 0.6 1.0326 0.9849 1237205 ChemDiv1_007229 Cc1ccc2nc(oc2c1)c3ccc(C)c(NC(=O)c4ccc5OCCOc5c4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I14 compound treatment 753647.0 188000.0 0.84 696518.0 123000.0 0.61 1.0264 0.9877 1973750 ChemDiv1_007230 COc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I15 compound treatment 776676.0 211000.0 0.94 703999.0 131000.0 0.65 1.1255 0.9831 1553870 ChemDiv1_007231 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I16 compound treatment 716080.0 150000.0 0.67 711045.0 138000.0 0.68 0.9584 1.0 1600380 ChemDiv1_007232 CCOC(=O)c1nc(Nc2ccc(C)c(Cl)c2)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I17 compound treatment 782231.0 216000.0 0.97 732204.0 159000.0 0.79 1.2419 0.9947 1731452 ChemDiv1_007233 OC(=O)CSc1nc2ccccc2n1c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I18 compound treatment 723230.0 157000.0 0.7 682313.0 109000.0 0.54 0.8804 0.9914 1973751 ChemDiv1_007234 COc1cc(ccc1NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I19 compound treatment 725989.0 160000.0 0.72 708149.0 135000.0 0.67 0.9796 0.9994 1973752 ChemDiv1_007235 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(N4CCN(C)CC4)c(c3)[N+](=O)[O-])/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I20 compound treatment 715226.0 149000.0 0.67 709158.0 136000.0 0.67 0.9491 1.0 1973753 ChemDiv1_007236 COc1cccc(c1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5cc(C)ccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I21 compound treatment 700523.0 135000.0 0.6 708575.0 135000.0 0.67 0.9005 0.9986 1470277 ChemDiv1_007237 O=C(Nc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I22 compound treatment 702272.0 136000.0 0.61 686488.0 113000.0 0.56 0.8287 0.9991 1973754 ChemDiv1_007238 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I23 mock treatment 672149.0 106000.0 0.48 685936.0 113000.0 0.56 0.7314 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 I24 mock treatment 576529.0 10700.0 0.05 532827.0 -40400.0 -0.2 -0.1076 -0.5228 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J01 compound treatment 599589.0 33800.0 0.15 565506.0 -7720.0 -0.04 0.0799 0.5121 1412864 ChemDiv1_007239 CCOc1ccc(cc1)N(CC(=O)Nc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J02 compound treatment 643786.0 78000.0 0.35 589813.0 16600.0 0.08 0.3049 0.8503 1973755 ChemDiv1_007240 COc1cc(cc(Br)c1OC)C2Nc3c(cccc3C4C=CCC42)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J03 compound treatment 689475.0 124000.0 0.55 648782.0 75600.0 0.37 0.6561 0.9818 1973756 ChemDiv1_007241 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCCCn3ccnc3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J04 compound treatment 667809.0 102000.0 0.46 630240.0 57000.0 0.28 0.5226 0.9733 1191341 ChemDiv1_007242 COc1ccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J05 compound treatment 718153.0 152000.0 0.68 632651.0 59400.0 0.29 0.6904 0.9295 1518064 ChemDiv1_007243 Cc1cc2N(C(=O)CSc3ncn[nH]3)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J06 compound treatment 684748.0 119000.0 0.53 653723.0 80500.0 0.4 0.6584 0.9899 1268622 ChemDiv1_007244 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J07 compound treatment 689712.0 124000.0 0.55 654895.0 81700.0 0.4 0.6783 0.988 1973757 ChemDiv1_007245 CCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J08 compound treatment 718898.0 153000.0 0.69 661422.0 88200.0 0.44 0.7935 0.9764 1862876 ChemDiv1_007246 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc3oc(nc3c2)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J09 compound treatment 723985.0 158000.0 0.71 667504.0 94300.0 0.47 0.8309 0.9796 1973758 ChemDiv1_007247 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)C)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J10 compound treatment 616559.0 50700.0 0.23 626196.0 53000.0 0.26 0.3462 0.9974 1973759 ChemDiv1_007248 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cccc(C)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J11 compound treatment 687872.0 122000.0 0.55 679224.0 106000.0 0.53 0.7576 0.9998 1107300 ChemDiv1_007249 CC(=O)Nc1ccc(Nc2nc(Cl)nc(Nc3ccc(NC(=O)C)cc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J12 compound treatment 673854.0 108000.0 0.48 646638.0 73400.0 0.36 0.5991 0.9901 1973760 ChemDiv1_007250 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J13 compound treatment 694108.0 128000.0 0.57 675241.0 102000.0 0.51 0.7634 0.998 1327797 ChemDiv1_007251 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4cccc(F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J14 compound treatment 727253.0 161000.0 0.72 679578.0 106000.0 0.53 0.8835 0.9879 1973761 ChemDiv1_007252 CCCOC(=O)C(CC)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J15 compound treatment 748298.0 182000.0 0.82 697198.0 124000.0 0.61 1.0119 0.9901 1323438 ChemDiv1_007253 Cc1c(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J16 compound treatment 694118.0 128000.0 0.57 671093.0 97900.0 0.48 0.7489 0.9964 1973762 ChemDiv1_007254 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3cc(C)cc(C)c3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J17 compound treatment 743162.0 177000.0 0.79 709942.0 137000.0 0.68 1.0403 0.9969 1195759 ChemDiv1_007255 Fc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J18 compound treatment 724903.0 159000.0 0.71 690329.0 117000.0 0.58 0.9138 0.9948 1973763 ChemDiv1_007256 COC(=O)C(C)Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J19 compound treatment 879010.0 313000.0 1.4 807886.0 235000.0 1.16 1.8133 0.9957 1630356 ChemDiv1_007257 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(o3)N4CCOCC4)c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J20 compound treatment 672520.0 107000.0 0.48 696398.0 123000.0 0.61 0.7692 0.9927 1973764 ChemDiv1_007258 OC(=O)c1cccc(NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J21 compound treatment 687882.0 122000.0 0.55 678145.0 105000.0 0.52 0.7539 0.9997 1923259 ChemDiv1_007259 CC1=C(C(NC(=O)N1)c2ccc(O)c(c2)[N+](=O)[O-])C(=O)OCc3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J22 compound treatment 728187.0 162000.0 0.73 701767.0 129000.0 0.64 0.9642 0.9978 1973765 ChemDiv1_007260 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C\C(=C\c3ccccc3)\C)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J23 mock treatment 658713.0 92900.0 0.42 677668.0 104000.0 0.52 0.6599 0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 J24 mock treatment 528397.0 -37400.0 -0.17 527527.0 -45700.0 -0.23 -0.2785 -0.989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K01 compound treatment 592915.0 27100.0 0.12 575487.0 2260.0 0.01 0.0937 0.7691 1973766 ChemDiv1_007261 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K02 compound treatment 638998.0 73200.0 0.33 617692.0 44500.0 0.22 0.3874 0.9813 1134909 ChemDiv1_007262 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K03 compound treatment 696685.0 131000.0 0.59 660562.0 87300.0 0.43 0.7202 0.9889 1973767 ChemDiv1_007263 COC(=O)C1=C(N)OC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K04 compound treatment 691095.0 125000.0 0.56 642680.0 69500.0 0.34 0.6398 0.9725 1973768 ChemDiv1_007264 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K05 compound treatment 708669.0 143000.0 0.64 671410.0 98200.0 0.49 0.7961 0.9909 1973769 ChemDiv1_007265 COC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K06 compound treatment 695484.0 130000.0 0.58 633601.0 60400.0 0.3 0.6219 0.9525 1307671 ChemDiv1_007266 OC1(CC(=O)c2ccncc2)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K07 compound treatment 747497.0 182000.0 0.81 677349.0 104000.0 0.52 0.9398 0.9759 1973770 ChemDiv1_007267 COc1cc(ccc1OCc2ccccc2)C3C(=C(N)OC4=C3C(=O)CC(C4)c5ccccc5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K08 compound treatment 715708.0 150000.0 0.67 671074.0 97800.0 0.48 0.8172 0.9873 1973771 ChemDiv1_007268 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K09 compound treatment 738825.0 173000.0 0.77 688727.0 116000.0 0.57 0.9522 0.9889 1973772 ChemDiv1_007269 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K10 compound treatment 703086.0 137000.0 0.61 665666.0 92400.0 0.46 0.7583 0.9895 1379264 ChemDiv1_007270 O=c1oc(nc2sc3CCCCCc3c12)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K11 compound treatment 706800.0 141000.0 0.63 695700.0 122000.0 0.61 0.8753 0.9998 1973773 ChemDiv1_007271 Cn1nc(Cl)c2ccccc2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K12 compound treatment 687864.0 122000.0 0.55 655950.0 82700.0 0.41 0.6761 0.99 1973774 ChemDiv1_007272 Clc1ccc2n(CC(=O)Nc3cc(Cl)cc(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K13 compound treatment 762641.0 197000.0 0.88 704138.0 131000.0 0.65 1.0816 0.9886 1163466 ChemDiv1_007273 COc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K14 compound treatment 742573.0 177000.0 0.79 674042.0 101000.0 0.5 0.9126 0.9754 1973775 ChemDiv1_007274 Cc1ccc2n(CC(=O)Nc3ccc(Oc4ccc(Cl)cc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K15 compound treatment 751896.0 186000.0 0.83 706014.0 133000.0 0.66 1.0541 0.9932 1313953 ChemDiv1_007275 CCOc1ccccc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K16 compound treatment 730193.0 164000.0 0.74 692081.0 119000.0 0.59 0.9366 0.9939 1973776 ChemDiv1_007276 Cc1ccc2n(CC(=O)Nc3c(F)cc(F)cc3Br)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K17 compound treatment 754117.0 188000.0 0.84 708398.0 135000.0 0.67 1.0695 0.9935 1142110 ChemDiv1_007277 CN(C)c1nc(N)c2n(C)cnc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K18 compound treatment 718276.0 152000.0 0.68 670445.0 97200.0 0.48 0.8231 0.9854 1973777 ChemDiv1_007278 Cc1ccc2n(CC(=O)Nc3cc(Sc4ccc(F)cc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K19 compound treatment 736249.0 170000.0 0.76 726650.0 153000.0 0.76 1.0769 1.0 1489299 ChemDiv1_007279 CCC(C)n1c(SCSc2nc3n(C)c(=O)n(C)c(=O)c3n2C(C)CC)nc4n(C)c(=O)n(C)c(=O)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K20 compound treatment 711496.0 146000.0 0.65 698126.0 125000.0 0.62 0.8986 0.9997 1350373 ChemDiv1_007280 CCOC(=O)c1nc(Nc2ccc(OC)cc2OC)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K21 compound treatment 743958.0 178000.0 0.8 731282.0 158000.0 0.78 1.1175 1.0 1973778 ChemDiv1_007281 BrCc1ccc2c(c1)c(nc3nnnn32)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K22 compound treatment 695158.0 129000.0 0.58 678054.0 105000.0 0.52 0.7766 0.9985 1973779 ChemDiv1_007282 Cc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(ccc24)[N+](=O)[O-])cc1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K23 mock treatment 693390.0 128000.0 0.57 693734.0 121000.0 0.6 0.8259 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 K24 mock treatment 535440.0 -30400.0 -0.14 450967.0 -122000.0 -0.61 -0.5244 -0.8448 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L01 compound treatment 592522.0 26700.0 0.12 544030.0 -29200.0 -0.14 -0.0177 -0.0945 1973780 ChemDiv1_007283 COc1ccc(N(CC(=O)Nc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3[N+](=O)[O-])c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L02 compound treatment 643773.0 78000.0 0.35 604920.0 31700.0 0.16 0.3578 0.935 1973781 ChemDiv1_007284 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc3OCOc3c2)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L03 compound treatment 687025.0 121000.0 0.54 651155.0 77900.0 0.39 0.6566 0.9861 1973782 ChemDiv1_007285 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCc3ccccn3)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L04 compound treatment 668142.0 102000.0 0.46 645578.0 72400.0 0.36 0.5773 0.9926 1590166 ChemDiv1_007286 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)S(=O)(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L05 compound treatment 685727.0 120000.0 0.54 647394.0 74200.0 0.37 0.6394 0.9829 1264058 ChemDiv1_007287 CCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L06 compound treatment 691759.0 126000.0 0.56 642543.0 69300.0 0.34 0.6415 0.9717 1973783 ChemDiv1_007288 [O-][N+](=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)S(=O)(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L07 compound treatment 678469.0 113000.0 0.5 628766.0 55500.0 0.28 0.5511 0.9594 1652038 ChemDiv1_007289 COc1ccccc1Nc2nc(Nc3ccccc3OC)nc(n2)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L08 compound treatment 688968.0 123000.0 0.55 658039.0 84800.0 0.42 0.6869 0.991 1973784 ChemDiv1_007290 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3c4ccc(cc4)C(F)(F)F)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L09 compound treatment 708898.0 143000.0 0.64 643387.0 70200.0 0.35 0.6987 0.9588 1218009 ChemDiv1_007291 CCOC(=O)c1sc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L10 compound treatment 711281.0 145000.0 0.65 664680.0 91500.0 0.45 0.7808 0.9843 1973785 ChemDiv1_007292 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4cccc(C)c4)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L11 compound treatment 703614.0 138000.0 0.62 661399.0 88200.0 0.44 0.745 0.9857 1973786 ChemDiv1_007293 COC(=O)c1cc(=O)n2ncnc2[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L12 compound treatment 684879.0 119000.0 0.53 654344.0 81100.0 0.4 0.661 0.9903 1167132 ChemDiv1_007294 CC(C)OC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L13 compound treatment 718158.0 152000.0 0.68 678450.0 105000.0 0.52 0.8508 0.9912 1653457 ChemDiv1_007295 COc1ccc2nc(SCC(=O)N3c4ccccc4C(=CC3(C)C)C)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L14 compound treatment 762847.0 197000.0 0.88 720852.0 148000.0 0.73 1.1408 0.9957 1494294 ChemDiv1_007296 CCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L15 compound treatment 745724.0 180000.0 0.81 675425.0 102000.0 0.51 0.9275 0.975 1462483 ChemDiv1_007297 COc1cc(cc(Br)c1OC)C2Nc3c(OC)ccc(Cl)c3C4C=CCC42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L16 compound treatment 721105.0 155000.0 0.7 687324.0 114000.0 0.57 0.8912 0.9947 1208479 ChemDiv1_007298 COc1ccccc1c2coc3cc(OC(C)C(=O)OCc4ccccc4)ccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L17 compound treatment 741312.0 175000.0 0.79 699259.0 126000.0 0.62 0.997 0.9935 1973787 ChemDiv1_007299 [O-][N+](=O)c1cccc(c1)N(CC(=O)N2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L18 compound treatment 654011.0 88200.0 0.39 620892.0 47700.0 0.24 0.4461 0.9698 1973788 ChemDiv1_007300 CCOCCOC(=O)COc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L19 compound treatment 783494.0 218000.0 0.97 733892.0 161000.0 0.8 1.2518 0.995 1248076 ChemDiv1_007301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4n(C)c(=O)n(C)c4c3)c(=O)n2C1c5ccc(cc5)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L20 compound treatment 720874.0 155000.0 0.69 688152.0 115000.0 0.57 0.8934 0.9952 1973789 ChemDiv1_007302 OC(=O)c1ccc(NC(=O)CCN2C(=O)/C(=C\c3cccc(Br)c3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L21 compound treatment 711732.0 146000.0 0.65 698586.0 125000.0 0.62 0.901 0.9997 1158641 ChemDiv1_007303 CCOc1cc(cc(Br)c1O)C2NC(=O)NC(=C2C(=O)OC(C)CC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L22 compound treatment 736732.0 171000.0 0.77 699219.0 126000.0 0.62 0.9823 0.9949 1973790 ChemDiv1_007304 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCC(=O)Nc3cc(C)on3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L23 mock treatment 673450.0 108000.0 0.48 661295.0 88100.0 0.44 0.6492 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 L24 mock treatment 530795.0 -35000.0 -0.16 521765.0 -51500.0 -0.25 -0.2911 -0.9727 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M01 compound treatment 628868.0 63100.0 0.28 583186.0 9960.0 0.05 0.2345 0.8183 1973791 ChemDiv1_007305 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M02 compound treatment 658740.0 92900.0 0.42 617542.0 44300.0 0.22 0.4494 0.9554 1480715 ChemDiv1_007306 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M03 compound treatment 701736.0 136000.0 0.61 677997.0 105000.0 0.52 0.7972 0.9969 1973792 ChemDiv1_007307 CCOC(=O)C1=C(N)OC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M04 compound treatment 749973.0 184000.0 0.82 763837.0 191000.0 0.94 1.2506 0.9977 1321881 ChemDiv1_007308 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M05 compound treatment 688604.0 123000.0 0.55 682124.0 109000.0 0.54 0.7701 1.0 1973793 ChemDiv1_007309 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M06 compound treatment 711291.0 145000.0 0.65 675714.0 102000.0 0.51 0.8195 0.9924 1126212 ChemDiv1_007310 Cc1ccc(cc1)C2=NN(C(C2)c3cc4cccc(C)c4nc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M07 compound treatment 734165.0 168000.0 0.75 712027.0 139000.0 0.69 1.0191 0.999 1973794 ChemDiv1_007311 COc1cc(cc(OC)c1OC)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M08 compound treatment 703122.0 137000.0 0.61 667005.0 93800.0 0.46 0.7631 0.9905 1562888 ChemDiv1_007312 CC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M09 compound treatment 731288.0 165000.0 0.74 668762.0 95500.0 0.47 0.8584 0.9766 1973795 ChemDiv1_007313 CCOc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M10 compound treatment 719874.0 154000.0 0.69 678622.0 105000.0 0.52 0.8568 0.9906 1663889 ChemDiv1_007314 Cc1cccc(c1)c2nc3sc4CCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M11 compound treatment 762708.0 197000.0 0.88 725727.0 153000.0 0.76 1.1574 0.9971 1973796 ChemDiv1_007315 CCOC(=O)Cn1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3cccc(Cl)c3Cl)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M12 compound treatment 717897.0 152000.0 0.68 685595.0 112000.0 0.56 0.875 0.995 1151782 ChemDiv1_007316 Cc1cc2nc(Cc3cc(Br)ccc3F)c(=O)[nH]c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M13 compound treatment 767196.0 201000.0 0.9 710657.0 137000.0 0.68 1.1188 0.9904 1718008 ChemDiv1_007317 Brc1ccc(cc1)c2ccc(COC(=O)c3ccc4OCCOc4c3)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M14 compound treatment 762919.0 197000.0 0.88 713402.0 140000.0 0.69 1.1149 0.993 1973797 ChemDiv1_007318 Cc1ccc2n(CC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M15 compound treatment 757885.0 192000.0 0.86 701644.0 128000.0 0.64 1.0578 0.989 1973798 ChemDiv1_007319 COc1ccc(cc1OC)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M16 compound treatment 706510.0 141000.0 0.63 677583.0 104000.0 0.52 0.8109 0.9952 1973799 ChemDiv1_007320 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccccc4)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M17 compound treatment 763904.0 198000.0 0.89 740163.0 167000.0 0.83 1.2118 0.9994 1973800 ChemDiv1_007321 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(OC)c(OC)c3OC)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M18 compound treatment 728774.0 163000.0 0.73 689293.0 116000.0 0.57 0.9224 0.9931 1973801 ChemDiv1_007322 Cc1ccc2n(CC(=O)Nc3ccccc3Br)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M19 compound treatment 738736.0 173000.0 0.77 722742.0 150000.0 0.74 1.0711 0.9998 1973802 ChemDiv1_007323 CC(C)c1ccc(/C=C/2\Sc3ccccc3C2=O)cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M20 compound treatment 705828.0 140000.0 0.63 698237.0 125000.0 0.62 0.8811 1.0 1413519 ChemDiv1_007324 CCOC(=O)c1nc(Nc2cc(Cl)ccc2OC)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M21 compound treatment 724484.0 159000.0 0.71 704863.0 132000.0 0.65 0.9633 0.9991 1190231 ChemDiv1_007325 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M22 compound treatment 700844.0 135000.0 0.6 683661.0 110000.0 0.55 0.8143 0.9988 1973803 ChemDiv1_007326 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M23 mock treatment 683627.0 118000.0 0.53 687139.0 114000.0 0.56 0.7719 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 M24 mock treatment 421131.0 -145000.0 -0.65 442278.0 -131000.0 -0.65 -0.9167 -1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N01 compound treatment 614115.0 48300.0 0.22 560727.0 -12500.0 -0.06 0.1091 0.4851 1207022 ChemDiv1_007327 CCOc1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N02 compound treatment 648556.0 82700.0 0.37 601307.0 28100.0 0.14 0.3603 0.9106 1345286 ChemDiv1_007328 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N03 compound treatment 695870.0 130000.0 0.58 650703.0 77500.0 0.38 0.6831 0.9796 1973804 ChemDiv1_007329 COCCN/C=C\1/C(=O)N(N=C1CSc2ccc(Cl)cc2)c3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N04 compound treatment 655296.0 89500.0 0.4 631470.0 58200.0 0.29 0.4873 0.987 1610755 ChemDiv1_007330 Cc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)S(=O)(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N05 compound treatment 701991.0 136000.0 0.61 636012.0 62800.0 0.31 0.651 0.9512 1231335 ChemDiv1_007331 COc1ccc(OC)c(Nc2nc(Cl)nc(Nc3cc(OC)ccc3OC)n2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N06 compound treatment 657586.0 91800.0 0.41 622458.0 49200.0 0.24 0.4629 0.969 1152306 ChemDiv1_007332 CC(NC(=O)c1ccc2OCCOc2c1)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N07 compound treatment 691263.0 125000.0 0.56 648411.0 75200.0 0.37 0.6604 0.9801 1973805 ChemDiv1_007333 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2Cl)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N08 compound treatment 668267.0 102000.0 0.46 656700.0 83500.0 0.41 0.6167 0.9987 1199748 ChemDiv1_007334 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CN3C(=O)c4ccccc4C3=O)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N09 compound treatment 702765.0 137000.0 0.61 659073.0 85800.0 0.43 0.7342 0.984 1973806 ChemDiv1_007335 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N10 compound treatment 681469.0 116000.0 0.52 632268.0 59000.0 0.29 0.5729 0.9635 1973807 ChemDiv1_007336 CCOCCOC(=O)COc1ccc2c(=O)c(c3cccc4ccccc34)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N11 compound treatment 798241.0 232000.0 1.04 718506.0 145000.0 0.72 1.2446 0.9838 1566144 ChemDiv1_007337 COc1ccc2nc(SC(=O)c3ccccc3Cl)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N12 compound treatment 668461.0 103000.0 0.46 636796.0 63600.0 0.31 0.5476 0.983 1973808 ChemDiv1_007338 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N13 compound treatment 711449.0 146000.0 0.65 668447.0 95200.0 0.47 0.7945 0.9874 1602963 ChemDiv1_007339 COc1ccc(cc1)N2C(=O)CC(Sc3nc(C)c4ccc(C)cc4n3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N14 compound treatment 712552.0 147000.0 0.66 663287.0 90100.0 0.45 0.7799 0.9822 1973809 ChemDiv1_007340 CCCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N15 compound treatment 716086.0 150000.0 0.67 645760.0 72500.0 0.36 0.7297 0.9569 1615587 ChemDiv1_007341 COc1ccc(cc1Br)S(=O)(=O)N(CC(=O)NCc2ccncc2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N16 compound treatment 707910.0 142000.0 0.64 647950.0 74700.0 0.37 0.7115 0.9668 1973810 ChemDiv1_007342 COc1ccccc1c2c(oc3cc(OCC(=O)OC(C)C)ccc3c2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N17 compound treatment 726136.0 160000.0 0.72 675430.0 102000.0 0.51 0.8655 0.9854 1658351 ChemDiv1_007343 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N18 compound treatment 704416.0 139000.0 0.62 669060.0 95800.0 0.47 0.7744 0.9913 1342406 ChemDiv1_007344 Clc1ccccc1c2nc(NCc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N19 compound treatment 700041.0 134000.0 0.6 694463.0 121000.0 0.6 0.8495 1.0 1399989 ChemDiv1_007345 COc1cc(ccc1OCc2ccccc2)C3NC(=O)NC(=C3C(=O)OCC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N20 compound treatment 689460.0 124000.0 0.55 667232.0 94000.0 0.47 0.7207 0.9963 1973811 ChemDiv1_007346 Brc1cccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccn3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N21 compound treatment 685153.0 119000.0 0.53 693469.0 120000.0 0.6 0.7989 0.9985 1417852 ChemDiv1_007347 COc1cc(cc(Cl)c1O)C2NC(=O)NC(=C2C(=O)OCCc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N22 compound treatment 778437.0 213000.0 0.95 763704.0 190000.0 0.94 1.3402 1.0 1973812 ChemDiv1_007348 C/C(=C\c1ccccc1)/C=C/2\SC(=S)N(CCC(=O)N(CCO)Cc3ccccc3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N23 mock treatment 647289.0 81500.0 0.36 644797.0 71600.0 0.35 0.5086 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 N24 mock treatment 316432.0 -249000.0 -1.12 422984.0 -150000.0 -0.74 -1.3156 -0.9806 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O01 compound treatment 613485.0 47700.0 0.21 583718.0 10500.0 0.05 0.1876 0.8544 1973813 ChemDiv1_007349 COC(=O)C1=C(N)OC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O02 compound treatment 633955.0 68100.0 0.31 597110.0 23900.0 0.12 0.2994 0.915 1973814 ChemDiv1_007350 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O03 compound treatment 659406.0 93600.0 0.42 633772.0 60500.0 0.3 0.5083 0.9866 1973815 ChemDiv1_007351 COC(=O)C1=C(N)OC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O04 compound treatment 629279.0 63500.0 0.28 624149.0 50900.0 0.25 0.3793 0.9982 1973816 ChemDiv1_007352 [O-][N+](=O)c1cccc(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O05 compound treatment 653941.0 88100.0 0.39 640105.0 66900.0 0.33 0.5132 0.9962 1973817 ChemDiv1_007353 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O06 compound treatment 660376.0 94600.0 0.42 621164.0 47900.0 0.24 0.4672 0.9627 1615949 ChemDiv1_007354 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(Cl)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O07 compound treatment 670128.0 104000.0 0.47 648620.0 75400.0 0.37 0.5943 0.9939 1973818 ChemDiv1_007355 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O08 compound treatment 671625.0 106000.0 0.47 636120.0 62900.0 0.31 0.5552 0.9794 1539017 ChemDiv1_007356 Cc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O09 compound treatment 674203.0 108000.0 0.49 663588.0 90400.0 0.45 0.6596 0.9992 1973819 ChemDiv1_007357 CCOC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O10 compound treatment 691328.0 126000.0 0.56 621648.0 48400.0 0.24 0.5669 0.928 1932431 ChemDiv1_007358 Cc1ccc(cc1)c2nc3sc4CCCCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O11 compound treatment 878353.0 313000.0 1.4 838586.0 265000.0 1.31 1.9188 0.9995 1973820 ChemDiv1_007359 Brc1ccc(cc1)N2C(=N)S/C(=C\c3ccc(cc3)N4CCOCC4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O12 compound treatment 674367.0 109000.0 0.49 635329.0 62100.0 0.31 0.5611 0.9757 1339205 ChemDiv1_007360 CCOC(=O)c1nc(Nc2cc(OC)cc(OC)c2)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O13 compound treatment 720809.0 155000.0 0.69 694588.0 121000.0 0.6 0.9157 0.9975 1443971 ChemDiv1_007361 CCOc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O14 compound treatment 677707.0 112000.0 0.5 642633.0 69400.0 0.34 0.5973 0.9832 1973821 ChemDiv1_007362 Cc1ccc2n(CC(=O)Nc3ccc(F)cc3Cl)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O15 compound treatment 662685.0 96900.0 0.43 669407.0 96200.0 0.48 0.6435 0.9989 1406723 ChemDiv1_007363 Cc1c(NC(=O)CN(c2ccccc2F)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O16 compound treatment 667264.0 101000.0 0.45 639760.0 66500.0 0.33 0.5542 0.9876 1973822 ChemDiv1_007364 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4cc(C)ccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O17 compound treatment 1766730.0 1200000.0 5.38 1747114.0 1170000.0 5.82 7.9132 0.9992 1973823 ChemDiv1_007365 CC(=O)/N=C/1\NC(=O)\C(=C\c2c(C)n(Cc3ccc(F)cc3)c4ccccc24)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O18 compound treatment 694613.0 129000.0 0.58 659925.0 86700.0 0.43 0.7114 0.9895 1973824 ChemDiv1_007366 Cc1ccc2n(CC(=O)Nc3c(C)cc(Br)cc3C)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O19 compound treatment 691240.0 125000.0 0.56 683952.0 111000.0 0.55 0.7849 0.9999 1973825 ChemDiv1_007367 COc1ccc(cc1)N2C(=N)S/C(=C\c3ccccc3[N+](=O)[O-])/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O20 compound treatment 675547.0 110000.0 0.49 641394.0 68200.0 0.34 0.5861 0.9833 1672328 ChemDiv1_007368 CCOC(=O)c1nc(Nc2cc(Cl)c(OC)cc2OC)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O21 compound treatment 693738.0 128000.0 0.57 684656.0 111000.0 0.55 0.7952 0.9998 1210895 ChemDiv1_007369 Cc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O22 compound treatment 637095.0 71300.0 0.32 628316.0 55100.0 0.27 0.4186 0.997 1973826 ChemDiv1_007370 [O-][N+](=O)c1ccc2n(CC(=O)Nc3cccc(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O23 mock treatment 647028.0 81200.0 0.36 654140.0 80900.0 0.4 0.5405 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 O24 mock treatment 257293.0 -309000.0 -1.38 466137.0 -107000.0 -0.53 -1.3517 -0.9136 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P01 compound treatment 579946.0 14100.0 0.06 567635.0 -5590.0 -0.03 0.0252 0.3642 1133791 ChemDiv1_007371 COc1ccc(OC)c(NC(=O)CN(c2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(C)cc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P02 compound treatment 602573.0 36800.0 0.16 554269.0 -19000.0 -0.09 0.05 0.2637 1628366 ChemDiv1_007372 Fc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P03 compound treatment 604870.0 39100.0 0.17 578077.0 4850.0 0.02 0.1406 0.7968 1973827 ChemDiv1_007373 Clc1ccc(SCC/2=NN(C(=O)\C2=C\NCc3ccc4OCOc4c3)c5nc6ccccc6s5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P04 compound treatment 606814.0 41000.0 0.18 565509.0 -7720.0 -0.04 0.1027 0.5481 1675971 ChemDiv1_007374 CCc1ccccc1N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P05 compound treatment 586272.0 20500.0 0.09 583700.0 10500.0 0.05 0.1014 0.9638 1973828 ChemDiv1_007375 CCCCCCCC1C(=O)NC(=S)N(C1=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P06 compound treatment 613396.0 47600.0 0.21 590853.0 17600.0 0.09 0.2124 0.9225 1359614 ChemDiv1_007376 OC(=O)CNC(=O)c1ccc2OCCOc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P07 compound treatment 618143.0 52300.0 0.23 592814.0 19600.0 0.1 0.2343 0.9239 1926191 ChemDiv1_007377 OC(=O)CCC(=O)N1N=C(CC1c2ccc(Br)cc2)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P08 compound treatment 626236.0 60400.0 0.27 595683.0 22500.0 0.11 0.2699 0.9229 1332575 ChemDiv1_007378 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(F)c3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P09 compound treatment 622210.0 56400.0 0.25 587984.0 14800.0 0.07 0.2302 0.8759 1870264 ChemDiv1_007379 OC(COc1ccc(cc1)[N+](=O)[O-])CN2C(=O)c3ccccc3S2(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P10 compound treatment 668550.0 103000.0 0.46 603633.0 30400.0 0.15 0.4317 0.8921 1658293 ChemDiv1_007380 COc1ccc(Oc2coc3cc(OC(C)C(=O)OC4CCCCC4)ccc3c2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P11 compound treatment 643821.0 78000.0 0.35 594329.0 21100.0 0.1 0.3208 0.8802 1241722 ChemDiv1_007381 Cn1cnc(SCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P12 compound treatment 637862.0 72000.0 0.32 599332.0 26100.0 0.13 0.3195 0.9195 1973829 ChemDiv1_007382 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccc(cc3)C(C)(C)C)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P13 compound treatment 645410.0 79600.0 0.36 584358.0 11100.0 0.06 0.2909 0.8069 1973830 ChemDiv1_007383 CC(=O)NS(=O)(=O)c1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P14 compound treatment 641492.0 75700.0 0.34 606570.0 33300.0 0.17 0.3563 0.9455 1973831 ChemDiv1_007384 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P15 compound treatment 638081.0 72300.0 0.32 583386.0 10200.0 0.05 0.2643 0.8074 1522436 ChemDiv1_007385 CC(C)c1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P16 compound treatment 638981.0 73200.0 0.33 590221.0 17000.0 0.08 0.2911 0.8609 1973832 ChemDiv1_007386 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(c3ccccc3OC)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P17 compound treatment 657613.0 91800.0 0.41 593558.0 20300.0 0.1 0.3618 0.8551 1973833 ChemDiv1_007387 COc1ccccc1/C=C\2/SC(=O)N(CCNC3=NS(=O)(=O)c4ccccc34)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P18 compound treatment 649135.0 83300.0 0.37 621684.0 48500.0 0.24 0.4335 0.9773 1699297 ChemDiv1_007388 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P19 compound treatment 628922.0 63100.0 0.28 608970.0 35700.0 0.18 0.325 0.9747 1936004 ChemDiv1_007389 CCOC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OCC)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P20 compound treatment 609547.0 43700.0 0.2 588593.0 15400.0 0.08 0.1923 0.9153 1973834 ChemDiv1_007390 Brc1cccc(/C=C/2\SC(=S)N(CCC(=O)Nc3nccs3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P21 compound treatment 664557.0 98700.0 0.44 644126.0 70900.0 0.35 0.5609 0.9935 1973835 ChemDiv1_007391 Cc1ccccc1CNC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P22 compound treatment 617293.0 51500.0 0.23 593182.0 20000.0 0.1 0.2329 0.9286 1973836 ChemDiv1_007392 CCOc1ccc(/C=C/2\SC(=S)N(CCCC(=O)N(CCO)Cc3ccccc3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P23 mock treatment 608275.0 42500.0 0.19 598347.0 25100.0 0.12 0.2224 0.9789 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.607 P24 mock treatment 460525.0 -105000.0 -0.47 183529.0 -390000.0 -1.93 -1.6983 -0.8546 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A01 compound treatment 601450.0 23300.0 0.1 538738.0 11100.0 0.05 0.1126 0.9549 1973837 ChemDiv1_007393 CCOc1ccc(/C=C/2\SC(=S)N(CCCC(=O)N(CCO)c3ccccc3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A02 compound treatment 594454.0 16300.0 0.07 524536.0 -3120.0 -0.02 0.0407 0.5453 1973838 ChemDiv1_007394 COc1cc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A03 compound treatment 635020.0 56900.0 0.25 532051.0 4390.0 0.02 0.1955 0.7647 1973839 ChemDiv1_007395 Cc1ccc(NC(=O)CC2S/C(=N/c3ccccc3)/N(C2=O)S(=O)(=O)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A04 compound treatment 615159.0 37000.0 0.17 520776.0 -6880.0 -0.03 0.0931 0.5501 1362513 ChemDiv1_007396 Cc1cccc(c1)c2nc3ccccc3c(=O)n2CC(=O)N4CCN(CC4)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A05 compound treatment 661753.0 83600.0 0.37 553186.0 25500.0 0.13 0.3541 0.8962 1494739 ChemDiv1_007397 COc1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A06 compound treatment 670725.0 92600.0 0.41 543874.0 16200.0 0.08 0.3499 0.8287 1268406 ChemDiv1_007398 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(CC)s3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A07 compound treatment 680167.0 102000.0 0.46 523770.0 -3890.0 -0.02 0.3094 0.6767 1732790 ChemDiv1_007399 Brc1ccc(cc1)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A08 compound treatment 664776.0 86700.0 0.39 539905.0 12200.0 0.06 0.3172 0.8079 1973840 ChemDiv1_007400 CCN(CC)CCOC(=O)c1ccc2OCCOc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A09 compound treatment 679660.0 102000.0 0.45 541423.0 13800.0 0.07 0.3696 0.8042 1690704 ChemDiv1_007401 COc1cc(cc(OC)c1OC)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A10 compound treatment 672707.0 94600.0 0.42 537991.0 10300.0 0.05 0.3356 0.7868 1973841 ChemDiv1_007402 Cc1cccc2cc(C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4)c(=O)[nH]c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A11 compound treatment 665450.0 87300.0 0.39 534802.0 7140.0 0.04 0.3014 0.768 1610980 ChemDiv1_007403 CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A12 compound treatment 681570.0 103000.0 0.46 554262.0 26600.0 0.13 0.4206 0.8736 1973842 ChemDiv1_007404 COc1ccccc1C2=NN(C(C2)c3ccccc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A13 compound treatment 675894.0 97800.0 0.44 548643.0 21000.0 0.1 0.383 0.8514 1396807 ChemDiv1_007405 CCOc1ccc2N(C(=O)CSc3nc4ccccc4o3)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A14 compound treatment 741905.0 164000.0 0.73 595385.0 67700.0 0.34 0.7556 0.9372 1973843 ChemDiv1_007406 Fc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A15 compound treatment 703861.0 126000.0 0.56 560102.0 32400.0 0.16 0.5116 0.8741 1973844 ChemDiv1_007407 Cc1ccc(OCCOc2ccc(cc2c3nc4sc5CCCCc5c4c(=O)[nH]3)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A16 compound treatment 679697.0 102000.0 0.45 556179.0 28500.0 0.14 0.4214 0.8851 1641522 ChemDiv1_007408 OC1(C2CCCCC2=O)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A17 compound treatment 699325.0 121000.0 0.54 556954.0 29300.0 0.15 0.4862 0.8658 1973845 ChemDiv1_007409 CCOc1cc(ccc1OCCOCCOc2ccc(C)c(C)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A18 compound treatment 671144.0 93000.0 0.42 559794.0 32100.0 0.16 0.407 0.913 1973846 ChemDiv1_007410 CCC1=NN(C(=O)c2ccc(cc2)c3ccccc3)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A19 compound treatment 666388.0 88300.0 0.4 541435.0 13800.0 0.07 0.3276 0.8171 1192276 ChemDiv1_007411 COc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A20 compound treatment 636809.0 58700.0 0.26 544005.0 16300.0 0.08 0.243 0.884 1973847 ChemDiv1_007412 CCCCC1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A21 compound treatment 629513.0 51400.0 0.23 548465.0 20800.0 0.1 0.2355 0.9344 1973848 ChemDiv1_007413 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(F)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A22 compound treatment 600447.0 22300.0 0.1 535247.0 7590.0 0.04 0.0972 0.9108 1951149 ChemDiv1_007414 CC1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A23 mock treatment 594798.0 16700.0 0.07 533168.0 5510.0 0.03 0.0721 0.9069 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 A24 mock treatment 525464.0 -52700.0 -0.24 510724.0 -16900.0 -0.08 -0.226 -0.9033 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B01 compound treatment 614360.0 36200.0 0.16 549464.0 21800.0 0.11 0.1911 0.9805 1425008 ChemDiv1_007415 CCOC(=O)C1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B02 compound treatment 661219.0 83100.0 0.37 545886.0 18200.0 0.09 0.3269 0.8539 1189334 ChemDiv1_007416 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCCOc4c3)c(=O)n2C1c5ccc(OC)c(OCC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B03 compound treatment 699295.0 121000.0 0.54 579420.0 51800.0 0.26 0.5648 0.9415 1973849 ChemDiv1_007417 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B04 compound treatment 696046.0 118000.0 0.53 561233.0 33600.0 0.17 0.4909 0.8869 1260710 ChemDiv1_007418 NNC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B05 compound treatment 712000.0 134000.0 0.6 612789.0 85100.0 0.42 0.7219 0.9852 1929100 ChemDiv1_007419 CCCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B06 compound treatment 725121.0 147000.0 0.66 559781.0 32100.0 0.16 0.5778 0.8535 1267335 ChemDiv1_007420 OC(=O)c1cccnc1SC2CC(=O)N(C2=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B07 compound treatment 776901.0 199000.0 0.89 595749.0 68100.0 0.34 0.8677 0.9118 1929004 ChemDiv1_007421 OC1(CC(=NN1C(=O)c2ccncc2)c3ccc(Cl)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B08 compound treatment 733439.0 155000.0 0.7 565251.0 37600.0 0.19 0.6233 0.866 1127121 ChemDiv1_007422 O=C(CN1C(=O)c2ccccc2S1(=O)=O)N3CCCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B09 compound treatment 755659.0 178000.0 0.79 584720.0 57100.0 0.28 0.7618 0.9032 1581989 ChemDiv1_007423 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B10 compound treatment 709685.0 132000.0 0.59 568321.0 40700.0 0.2 0.5589 0.8979 1639012 ChemDiv1_007424 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccc(Oc5ccccc5)cc4)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B11 compound treatment 733701.0 156000.0 0.7 596652.0 69000.0 0.34 0.7341 0.9463 1483209 ChemDiv1_007425 CCC1=NN(C(=O)c2cccc(C)c2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B12 compound treatment 709711.0 132000.0 0.59 573854.0 46200.0 0.23 0.5783 0.9152 1537413 ChemDiv1_007426 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2Cc5csc(n5)c6ccc(Cl)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B13 compound treatment 740606.0 162000.0 0.73 602558.0 74900.0 0.37 0.7767 0.9512 1928954 ChemDiv1_007427 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B14 compound treatment 740743.0 163000.0 0.73 578874.0 51200.0 0.25 0.6941 0.9004 1148077 ChemDiv1_007428 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3CC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B15 compound treatment 741973.0 164000.0 0.73 611820.0 84200.0 0.42 0.8134 0.9642 1973850 ChemDiv1_007429 Cc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B16 compound treatment 767434.0 189000.0 0.85 603063.0 75400.0 0.37 0.8633 0.9322 1323871 ChemDiv1_007430 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(OC)cc3OC)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B17 compound treatment 719159.0 141000.0 0.63 616323.0 88700.0 0.44 0.757 0.9843 1929035 ChemDiv1_007431 COc1cccc(c1)C2=NN(C(=O)c3cccc(Br)c3)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B18 compound treatment 709012.0 131000.0 0.59 566792.0 39100.0 0.19 0.5514 0.8934 1611743 ChemDiv1_007432 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)NCCc5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B19 compound treatment 732782.0 155000.0 0.69 584054.0 56400.0 0.28 0.6871 0.9203 1973851 ChemDiv1_007433 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C\c3ccccc3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B20 compound treatment 687426.0 109000.0 0.49 579131.0 51500.0 0.25 0.5263 0.9538 1168744 ChemDiv1_007434 COc1ccccc1CNc2nc(nc3ccccc23)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B21 compound treatment 701563.0 123000.0 0.55 585450.0 57800.0 0.29 0.5931 0.9531 1973852 ChemDiv1_007435 COc1cc(Br)c(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B22 compound treatment 659185.0 81100.0 0.36 557681.0 30000.0 0.15 0.3617 0.9224 1131374 ChemDiv1_007436 COc1ccc(cc1OC)c2nc(N3CCN(C)CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B23 mock treatment 657277.0 79200.0 0.35 578767.0 51100.0 0.25 0.4296 0.9864 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 B24 mock treatment 484520.0 -93600.0 -0.42 510347.0 -17300.0 -0.09 -0.3569 -0.8345 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C01 compound treatment 603142.0 25000.0 0.11 530153.0 2490.0 0.01 0.0879 0.7803 1973853 ChemDiv1_007437 CCOc1ccc(/C=C\2/SC(=S)N(CCC(=O)N3CCC(Cc4ccccc4)CC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C02 compound treatment 672750.0 94600.0 0.42 556960.0 29300.0 0.15 0.4021 0.8981 1973854 ChemDiv1_007438 FC(F)(F)c1ccc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C03 compound treatment 742208.0 164000.0 0.73 583175.0 55500.0 0.28 0.7138 0.9102 1973855 ChemDiv1_007439 O=C(CC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C04 compound treatment 706329.0 128000.0 0.57 552916.0 25300.0 0.13 0.4943 0.8415 1215589 ChemDiv1_007440 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4cccc(F)c4)c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C05 compound treatment 754288.0 176000.0 0.79 571512.0 43900.0 0.22 0.7112 0.8695 1946354 ChemDiv1_007441 [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c3ccc4OCCOc4c3)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C06 compound treatment 725536.0 147000.0 0.66 539633.0 12000.0 0.06 0.5085 0.7676 1780066 ChemDiv1_007442 CCc1sc(cc1[N+](=O)[O-])c2c(C#N)c(N)nc3CCCCCCc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C07 compound treatment 771731.0 194000.0 0.87 571740.0 44100.0 0.22 0.7672 0.8584 1668262 ChemDiv1_007443 COc1cc(cc(OC)c1O)C2Nc3ccc(cc3NC4=C2C(=O)CCC4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C08 compound treatment 766385.0 188000.0 0.84 565516.0 37900.0 0.19 0.7285 0.8438 1973856 ChemDiv1_007444 CN(C)CCCOC(=O)c1ccc2OCCOc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C09 compound treatment 764589.0 186000.0 0.83 591970.0 64300.0 0.32 0.8155 0.9128 1973857 ChemDiv1_007445 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C10 compound treatment 733807.0 156000.0 0.7 549252.0 21600.0 0.11 0.5684 0.8062 1973858 ChemDiv1_007446 Cc1ccc2[nH]c(=O)c(cc2c1)C3CC(=NN3C(=O)CCC(=O)O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C11 compound treatment 751503.0 173000.0 0.78 590178.0 62500.0 0.31 0.7678 0.9188 1973859 ChemDiv1_007447 CN1C(=O)C(CC(=O)C)(OC(=O)C)c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C12 compound treatment 750731.0 173000.0 0.77 577454.0 49800.0 0.25 0.7208 0.8887 1973860 ChemDiv1_007448 Fc1ccc(cc1)C(=O)N2N=C(CC2c3ccco3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C13 compound treatment 742711.0 165000.0 0.74 587328.0 59700.0 0.3 0.73 0.9195 1700808 ChemDiv1_007449 Cc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C14 compound treatment 707225.0 129000.0 0.58 582896.0 55200.0 0.27 0.6021 0.9417 1973861 ChemDiv1_007450 FC(F)(F)C(=O)NC(CC(=O)Nc1nnc(CCc2ccccc2)s1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C15 compound treatment 775278.0 197000.0 0.88 594036.0 66400.0 0.33 0.8566 0.9095 1973862 ChemDiv1_007451 COc1cccc(OCCOc2ccc(cc2OC)c3nc4sc5CCCCc5c4c(=O)[nH]3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C16 compound treatment 757207.0 179000.0 0.8 574408.0 46700.0 0.23 0.7306 0.8756 1083083 ChemDiv1_007452 OC1(C2CCCCCC2=O)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C17 compound treatment 780704.0 203000.0 0.91 610566.0 82900.0 0.41 0.9316 0.9358 1654302 ChemDiv1_007453 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C18 compound treatment 714573.0 136000.0 0.61 574511.0 46900.0 0.23 0.596 0.9122 1973863 ChemDiv1_007454 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C19 compound treatment 768430.0 190000.0 0.85 589990.0 62300.0 0.31 0.8207 0.9057 1305788 ChemDiv1_007455 OC1(CC(=O)c2ccc3CCc4cccc2c43)C(=O)N(Cc5ccc(Cl)cc5)c6ccccc61 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C20 compound treatment 714378.0 136000.0 0.61 573950.0 46300.0 0.23 0.5934 0.9107 1934703 ChemDiv1_007456 CC1=NN(C(=O)c2cccc(Br)c2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C21 compound treatment 724294.0 146000.0 0.65 588540.0 60900.0 0.3 0.6759 0.9382 1973864 ChemDiv1_007457 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C22 compound treatment 665827.0 87700.0 0.39 571655.0 44000.0 0.22 0.4317 0.9614 1556482 ChemDiv1_007458 CC1=NN(C(=O)CCCc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C23 mock treatment 673275.0 95200.0 0.43 589363.0 61700.0 0.31 0.5173 0.9868 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 C24 mock treatment 529179.0 -48900.0 -0.22 504400.0 -23300.0 -0.12 -0.2364 -0.955 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D01 compound treatment 627817.0 49700.0 0.22 550081.0 22400.0 0.11 0.2358 0.9485 1973865 ChemDiv1_007459 CCOC(=O)C1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D02 compound treatment 644629.0 66500.0 0.3 553897.0 26200.0 0.13 0.3024 0.931 1527668 ChemDiv1_007460 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D03 compound treatment 695599.0 117000.0 0.53 570316.0 42700.0 0.21 0.5213 0.9198 1929036 ChemDiv1_007461 OC1(CC(=NN1C(=O)CCc2ccccc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D04 compound treatment 654890.0 76800.0 0.34 565470.0 37800.0 0.19 0.3754 0.9593 1337823 ChemDiv1_007462 O=C(NCC1OCCc2ccccc12)C3COc4ccccc4O3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D05 compound treatment 738713.0 161000.0 0.72 584185.0 56500.0 0.28 0.7063 0.9155 1928924 ChemDiv1_007463 CCCC1=NN(C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D06 compound treatment 1238587.0 660000.0 2.96 1038927.0 511000.0 2.53 3.8814 0.997 1973866 ChemDiv1_007464 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3ccccc3)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D07 compound treatment 747295.0 169000.0 0.76 585880.0 58200.0 0.29 0.7394 0.9125 1928881 ChemDiv1_007465 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D08 compound treatment 743323.0 165000.0 0.74 580205.0 52500.0 0.26 0.707 0.9018 1973867 ChemDiv1_007466 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D09 compound treatment 754158.0 176000.0 0.79 589687.0 62000.0 0.31 0.7745 0.9157 1928400 ChemDiv1_007467 CC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D10 compound treatment 826334.0 248000.0 1.11 740902.0 213000.0 1.06 1.5326 0.9997 1973868 ChemDiv1_007468 Cc1ccc2n(CC(=O)Nc3cc(Oc4ccc(F)cc4F)cc(c3)[N+](=O)[O-])c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D11 compound treatment 732882.0 155000.0 0.69 606814.0 79200.0 0.39 0.7671 0.9637 1393138 ChemDiv1_007469 CCC1=NN(C(=O)c2cccnc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D12 compound treatment 692389.0 114000.0 0.51 593638.0 66000.0 0.33 0.5928 0.9766 1486493 ChemDiv1_007470 COc1ccc(NC(=O)Cn2c(nc3sc(C)c(C)c3c2=O)c4ccccc4Cl)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D13 compound treatment 753911.0 176000.0 0.79 594666.0 67000.0 0.33 0.7911 0.9263 1973869 ChemDiv1_007471 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(Br)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D14 compound treatment 714372.0 136000.0 0.61 601732.0 74100.0 0.37 0.6907 0.9704 1268546 ChemDiv1_007472 CCOC(=O)c1sc2nc(C)nc(NCc3ccccc3OC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D15 compound treatment 776382.0 198000.0 0.89 611487.0 83800.0 0.42 0.9212 0.9401 1929183 ChemDiv1_007473 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D16 compound treatment 720195.0 142000.0 0.64 577233.0 49600.0 0.25 0.6233 0.9143 1613071 ChemDiv1_007474 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(F)c(Cl)c3)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D17 compound treatment 716070.0 138000.0 0.62 621840.0 94200.0 0.47 0.7665 0.9904 1928928 ChemDiv1_007475 COc1cccc(c1)C2=NN(C(=O)CCc3ccccc3)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D18 compound treatment 723441.0 145000.0 0.65 577126.0 49500.0 0.25 0.6332 0.911 1973870 ChemDiv1_007476 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccccc4C(F)(F)F)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D19 compound treatment 746618.0 168000.0 0.75 618654.0 91000.0 0.45 0.8521 0.9697 1951899 ChemDiv1_007477 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C/c3ccco3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D20 compound treatment 710961.0 133000.0 0.59 583990.0 56300.0 0.28 0.6178 0.9405 1696244 ChemDiv1_007478 CCC(C)Nc1nc(nc2ccccc12)c3cc(OC)c(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D21 compound treatment 725197.0 147000.0 0.66 601510.0 73800.0 0.37 0.7242 0.9615 1973871 ChemDiv1_007479 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)ccc1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D22 compound treatment 694713.0 117000.0 0.52 579723.0 52100.0 0.26 0.5514 0.9472 1719783 ChemDiv1_007480 COc1ccc(cc1OC)c2nc(N3CCC(C)CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D23 mock treatment 684710.0 107000.0 0.48 578361.0 50700.0 0.25 0.515 0.9551 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 D24 mock treatment 477495.0 -101000.0 -0.45 516463.0 -11200.0 -0.06 -0.3577 -0.7882 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E01 compound treatment 657855.0 79700.0 0.36 549030.0 21400.0 0.11 0.3272 0.879 1973872 ChemDiv1_007481 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cc(C)on3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E02 compound treatment 681806.0 104000.0 0.46 539431.0 11800.0 0.06 0.3694 0.7897 1973873 ChemDiv1_007482 Clc1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E03 compound treatment 718025.0 140000.0 0.63 609178.0 81500.0 0.4 0.7284 0.9775 1973874 ChemDiv1_007483 CCCCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E04 compound treatment 715416.0 137000.0 0.61 573906.0 46200.0 0.23 0.5966 0.9096 1851246 ChemDiv1_007484 COc1cc(ccc1OCc2ccc(cc2)[N+](=O)[O-])C3C(=C(N)OC4=C3C(=O)CCC4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E05 compound treatment 737352.0 159000.0 0.71 581947.0 54300.0 0.27 0.6942 0.9112 1141167 ChemDiv1_007485 CCOC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E06 compound treatment 851643.0 274000.0 1.22 657035.0 129000.0 0.64 1.3189 0.9544 1973875 ChemDiv1_007486 CCCC1=C(C(c2cc(OC)ccc2OC)n3c(=O)c(=Cc4ccc(o4)[N+](=O)[O-])sc3=N1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E07 compound treatment 810990.0 233000.0 1.04 628349.0 101000.0 0.5 1.0898 0.9431 1973876 ChemDiv1_007487 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E08 compound treatment 762997.0 185000.0 0.83 597461.0 69800.0 0.35 0.8297 0.9251 1180781 ChemDiv1_007488 CN(CCOC(=O)c1ccc2OCCOc2c1)Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E09 compound treatment 784935.0 207000.0 0.93 588672.0 61000.0 0.3 0.8683 0.8916 1973877 ChemDiv1_007489 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E10 compound treatment 749490.0 171000.0 0.77 603101.0 75400.0 0.37 0.8067 0.9454 1598542 ChemDiv1_007490 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccccc3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E11 compound treatment 724566.0 146000.0 0.66 623698.0 96000.0 0.48 0.7999 0.9876 1135758 ChemDiv1_007491 CC1=CC(C)(C)N(C(=O)CSc2nc3ccccc3o2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E12 compound treatment 750808.0 173000.0 0.77 607893.0 80200.0 0.4 0.8276 0.9522 1783640 ChemDiv1_007492 OC(=O)CCC(=O)N1N=C(CC1c2cccc(c2)[N+](=O)[O-])c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E13 compound treatment 723539.0 145000.0 0.65 609436.0 81800.0 0.41 0.7467 0.974 1376685 ChemDiv1_007493 Cc1cc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E14 compound treatment 758093.0 180000.0 0.81 602374.0 74700.0 0.37 0.8314 0.9377 1950838 ChemDiv1_007494 O=C1C2C(C3C=CC2C4C3C(=O)N(Cc5cccnc5)C4=O)C(=O)N1Cc6cccnc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E15 compound treatment 792895.0 215000.0 0.96 611754.0 84100.0 0.42 0.9744 0.93 1973878 ChemDiv1_007495 CCOc1cc(ccc1OCCOc2cccc(OC)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E16 compound treatment 764969.0 187000.0 0.84 604158.0 76500.0 0.38 0.8594 0.9359 1704765 ChemDiv1_007496 OC1(CC(=O)c2cccs2)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E17 compound treatment 781096.0 203000.0 0.91 616780.0 89100.0 0.44 0.9546 0.945 1705505 ChemDiv1_007497 C(Oc1cccc(c1)C2Oc3ccccc3C4CC(=NN42)c5ccccc5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E18 compound treatment 715984.0 138000.0 0.62 601611.0 74000.0 0.37 0.6954 0.969 1973879 ChemDiv1_007498 OC1(CC(=NN1C(=O)c2ccc(Br)cc2)c3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E19 compound treatment 764975.0 187000.0 0.84 610987.0 83300.0 0.41 0.8833 0.947 1211788 ChemDiv1_007499 CC(C(=O)c1ccccc1)C2(O)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E20 compound treatment 739012.0 161000.0 0.72 582798.0 55100.0 0.27 0.7024 0.9119 1973880 ChemDiv1_007500 CC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E21 compound treatment 761420.0 183000.0 0.82 600021.0 72400.0 0.36 0.8337 0.9311 1973881 ChemDiv1_007501 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc(OCc4ccccc4)cc3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E22 compound treatment 716990.0 139000.0 0.62 596571.0 68900.0 0.34 0.6809 0.9602 1973882 ChemDiv1_007502 CCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E23 mock treatment 690522.0 112000.0 0.5 583221.0 55600.0 0.28 0.5504 0.9597 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 E24 mock treatment 533909.0 -44200.0 -0.2 529813.0 2150.0 0.01 -0.1324 -0.668 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F01 compound treatment 674207.0 96100.0 0.43 568277.0 40600.0 0.2 0.4464 0.9401 1137802 ChemDiv1_007503 COC(=O)C1=NN(C(=O)c2cccc(OC)c2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F02 compound treatment 677511.0 99400.0 0.44 550697.0 23000.0 0.11 0.3953 0.8606 1431491 ChemDiv1_007504 Clc1ccc(cc1)C(=O)CSc2ncnc3[nH]cnc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F03 compound treatment 638837.0 60700.0 0.27 559087.0 31400.0 0.16 0.3023 0.965 1973883 ChemDiv1_007505 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F04 compound treatment 699944.0 122000.0 0.55 578795.0 51100.0 0.25 0.5647 0.9392 1385162 ChemDiv1_007506 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cc(ccc2Cl)c3nc4ccc(C)cc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F05 compound treatment 722607.0 144000.0 0.65 588184.0 60500.0 0.3 0.6693 0.9389 1973884 ChemDiv1_007507 CC(C)(C)C1(O)CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F06 compound treatment 2622687.0 2040000.0 9.15 2768777.0 2240000.0 11.1 14.3219 0.9954 1973885 ChemDiv1_007508 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F07 compound treatment 775048.0 197000.0 0.88 614036.0 86400.0 0.43 0.9259 0.9449 1928940 ChemDiv1_007509 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)c3ccc(Cl)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F08 compound treatment 767269.0 189000.0 0.85 596456.0 68800.0 0.34 0.8397 0.92 1973886 ChemDiv1_007510 Clc1ccc(Oc2ccc(NC(=O)Cn3c4ccccc4c(=O)c5ccc(Cl)cc35)cc2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F09 compound treatment 747816.0 170000.0 0.76 614212.0 86600.0 0.43 0.8403 0.9634 1166343 ChemDiv1_007511 CCC1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F10 compound treatment 731011.0 153000.0 0.68 621572.0 93900.0 0.47 0.8129 0.9823 1973887 ChemDiv1_007512 [O-][N+](=O)c1cc(NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc(Oc5ccc(F)cc5F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F11 compound treatment 828477.0 250000.0 1.12 678093.0 150000.0 0.75 1.3194 0.9803 1532841 ChemDiv1_007513 CCC1=NN(C(=O)c2ccncc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F12 compound treatment 720707.0 143000.0 0.64 616102.0 88400.0 0.44 0.7611 0.9831 1338234 ChemDiv1_007514 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccccc3Cl)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F13 compound treatment 755429.0 177000.0 0.79 620473.0 92800.0 0.46 0.8863 0.9663 1973888 ChemDiv1_007515 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F14 compound treatment 729844.0 152000.0 0.68 620616.0 93000.0 0.46 0.8058 0.9821 1479828 ChemDiv1_007516 CCOC(=O)c1sc2nc(C)nc(N(C)C3CCCCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F15 compound treatment 704364.0 126000.0 0.57 630863.0 103000.0 0.51 0.7611 0.9988 1929087 ChemDiv1_007517 OC1(CC(=NN1C(=O)Cc2ccccc2)c3cccc(Br)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F16 compound treatment 746988.0 169000.0 0.76 604222.0 76600.0 0.38 0.8027 0.9491 1344354 ChemDiv1_007518 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F17 compound treatment 798149.0 220000.0 0.98 641611.0 114000.0 0.56 1.0956 0.9651 1948811 ChemDiv1_007519 COc1cccc(c1)C2=NN(C(=O)c3ccc(cc3)C(C)(C)C)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F18 compound treatment 729717.0 152000.0 0.68 600559.0 72900.0 0.36 0.7352 0.9564 1973889 ChemDiv1_007520 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)Nc5ccccc5C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F19 compound treatment 748920.0 171000.0 0.76 625088.0 97400.0 0.48 0.8819 0.9754 1973890 ChemDiv1_007521 Cc1ncc([N+](=O)[O-])n1CCSc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F20 compound treatment 715995.0 138000.0 0.62 601536.0 73900.0 0.37 0.6952 0.9689 1319714 ChemDiv1_007522 COc1cc(cc(OC)c1OC)c2nc(N3CCC(C)CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F21 compound treatment 706443.0 128000.0 0.57 604737.0 77100.0 0.38 0.6762 0.9803 1973891 ChemDiv1_007523 CCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F22 compound treatment 693734.0 116000.0 0.52 573906.0 46200.0 0.23 0.5279 0.9328 1973892 ChemDiv1_007524 COc1cc(cc(OC)c1OC)c2nc(Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F23 mock treatment 677136.0 99000.0 0.44 574029.0 46400.0 0.23 0.4758 0.9532 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 F24 mock treatment 458651.0 -119000.0 -0.53 523426.0 -4230.0 -0.02 -0.393 -0.7343 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G01 compound treatment 662039.0 83900.0 0.38 566609.0 38900.0 0.19 0.402 0.9521 1973893 ChemDiv1_007525 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)NC3=NCCS3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G02 compound treatment 759682.0 182000.0 0.81 562644.0 35000.0 0.17 0.6972 0.839 1973894 ChemDiv1_007526 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)C(=O)Cn3c4ccccc4c(=O)c5cc(Cl)ccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G03 compound treatment 734114.0 156000.0 0.7 603512.0 75900.0 0.38 0.7594 0.9577 1973895 ChemDiv1_007527 CCCCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G04 compound treatment 706282.0 128000.0 0.57 573909.0 46200.0 0.23 0.5677 0.9189 1851266 ChemDiv1_007528 COC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccc(cc4)[N+](=O)[O-])c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G05 compound treatment 745729.0 168000.0 0.75 603070.0 75400.0 0.37 0.7947 0.9482 1179146 ChemDiv1_007529 COC(=O)COC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G06 compound treatment 749635.0 172000.0 0.77 594417.0 66800.0 0.33 0.7767 0.9292 1691466 ChemDiv1_007530 COc1ccc2c3CCN(CCC(=O)NN)C(C)c3[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G07 compound treatment 762165.0 184000.0 0.82 609532.0 81900.0 0.41 0.8693 0.9467 1973896 ChemDiv1_007531 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4cc5OCOc5cc4[N+](=O)[O-])C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G08 compound treatment 771787.0 194000.0 0.87 587242.0 59600.0 0.3 0.8217 0.8973 1300480 ChemDiv1_007532 O=C(Oc1cc(=O)oc2ccccc12)c3ccc4OCCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G09 compound treatment 762196.0 184000.0 0.82 640215.0 113000.0 0.56 0.9769 0.9819 1973897 ChemDiv1_007533 CC1(C)Cc2c(CO1)sc3nc(SCC=C)n(Cc4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G10 compound treatment 737330.0 159000.0 0.71 627997.0 100000.0 0.5 0.8554 0.9845 1256212 ChemDiv1_007534 COc1cccc(C2CC(=NN2C(=O)CCC(=O)O)c3ccc(C)cc3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G11 compound treatment 768633.0 191000.0 0.85 629915.0 102000.0 0.51 0.9612 0.9691 1419221 ChemDiv1_007535 CC1(C)N(C(=O)CSc2nc3ccccc3o2)c4ccccc4-c5c1ssc5=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G12 compound treatment 774991.0 197000.0 0.88 648577.0 121000.0 0.6 1.0467 0.9823 1973898 ChemDiv1_007536 OC(=O)CCC(=O)N1N=C(CC1c2ccc(F)cc2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G13 compound treatment 766221.0 188000.0 0.84 600679.0 73000.0 0.36 0.8512 0.9288 1680965 ChemDiv1_007537 CCOc1ccc2N(C(=O)CSc3nncn3C)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G14 compound treatment 738402.0 160000.0 0.72 637903.0 110000.0 0.55 0.8935 0.9909 1941625 ChemDiv1_007538 Fc1ccc(CN2C(=O)C3C(C4C=CC3C5C4C(=O)N(Cc6ccc(F)cc6)C5=O)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G15 compound treatment 813390.0 235000.0 1.05 650089.0 122000.0 0.61 1.1735 0.9656 1973899 ChemDiv1_007539 COc1ccccc1OCCOc2ccc(cc2c3nc4sc5CCCCc5c4c(=O)[nH]3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G16 compound treatment 772232.0 194000.0 0.87 627564.0 99900.0 0.49 0.9644 0.9644 1341286 ChemDiv1_007540 OC1(CC(=O)c2ccco2)C(=O)Nc3ccccc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G17 compound treatment 769068.0 191000.0 0.85 667125.0 139000.0 0.69 1.0929 0.9944 1493770 ChemDiv1_007541 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G18 compound treatment 808299.0 230000.0 1.03 647328.0 120000.0 0.59 1.1477 0.9655 1973900 ChemDiv1_007542 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G19 compound treatment 786701.0 209000.0 0.93 623259.0 95600.0 0.47 0.9951 0.9505 1366573 ChemDiv1_007543 COc1ccc(C(=O)CC2(O)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc42)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G20 compound treatment 730374.0 152000.0 0.68 613853.0 86200.0 0.43 0.7838 0.9746 1951330 ChemDiv1_007544 CC1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G21 compound treatment 676423.0 98300.0 0.44 622458.0 94800.0 0.47 0.6432 0.9995 1973901 ChemDiv1_007545 [O-][N+](=O)c1ccc2n(CC(=O)Nc3ccc4CCCc4c3)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G22 compound treatment 719739.0 142000.0 0.63 593989.0 66300.0 0.33 0.6806 0.9532 1951729 ChemDiv1_007546 CCOC(=O)C1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G23 mock treatment 701455.0 123000.0 0.55 609266.0 81600.0 0.4 0.6762 0.9883 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 G24 mock treatment 552087.0 -26000.0 -0.12 513735.0 -13900.0 -0.07 -0.1312 -0.9687 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H01 compound treatment 629545.0 51400.0 0.23 544897.0 17200.0 0.09 0.2231 0.9089 1703408 ChemDiv1_007547 COC(=O)C1=NN(C(=O)c2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H02 compound treatment 645172.0 67000.0 0.3 530424.0 2760.0 0.01 0.2219 0.7386 1546110 ChemDiv1_007548 CC1(C)CC(=O)C(Sc2ncnc3[nH]cnc23)C(=O)C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H03 compound treatment 702160.0 124000.0 0.56 550882.0 23200.0 0.12 0.474 0.8359 1973902 ChemDiv1_007549 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])c3ccncc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H04 compound treatment 688378.0 110000.0 0.49 564127.0 36500.0 0.18 0.4767 0.9071 1175782 ChemDiv1_007550 CC1=C(C(NC(=O)N1)c2cccc(Br)c2)C(=O)OCc3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H05 compound treatment 712516.0 134000.0 0.6 571922.0 44300.0 0.22 0.5804 0.9065 1928903 ChemDiv1_007551 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H06 compound treatment 696841.0 119000.0 0.53 595757.0 68100.0 0.34 0.6143 0.9759 1443813 ChemDiv1_007552 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H07 compound treatment 710579.0 132000.0 0.59 596232.0 68600.0 0.34 0.6595 0.9651 1928999 ChemDiv1_007553 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H08 compound treatment 721758.0 144000.0 0.64 605394.0 77700.0 0.39 0.7269 0.9699 1599610 ChemDiv1_007554 COc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4F)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H09 compound treatment 849822.0 272000.0 1.22 683492.0 156000.0 0.77 1.4059 0.9759 1208313 ChemDiv1_007555 CCC1=NN(C(=O)c2cccc(C)c2O)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H10 compound treatment 764321.0 186000.0 0.83 625955.0 98300.0 0.49 0.9337 0.9672 1664726 ChemDiv1_007556 COc1ccc(Cc2nc3cc(C)c(C)cc3n(C)c2=O)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H11 compound treatment 776763.0 199000.0 0.89 707183.0 180000.0 0.89 1.2576 1.0 1973903 ChemDiv1_007557 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H12 compound treatment 710579.0 132000.0 0.59 634744.0 107000.0 0.53 0.7944 0.9985 1358536 ChemDiv1_007558 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccc(C)cc3)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H13 compound treatment 722056.0 144000.0 0.64 623230.0 95600.0 0.47 0.7904 0.9885 1973904 ChemDiv1_007559 OC1(CC(=NN1C(=O)c2ccccc2)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H14 compound treatment 697137.0 119000.0 0.53 625635.0 98000.0 0.49 0.7199 0.9989 1414412 ChemDiv1_007560 CCOC(=O)c1nc(N2CCN(CC2)c3ccccc3)c4ccccc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H15 compound treatment 783762.0 206000.0 0.92 657290.0 130000.0 0.64 1.105 0.9845 1928917 ChemDiv1_007561 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H16 compound treatment 709863.0 132000.0 0.59 627964.0 100000.0 0.5 0.7683 0.9964 1335128 ChemDiv1_007562 CCN(CC)C(=O)COc1nc(Cc2ccccc2)nc3sc4CCCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H17 compound treatment 770510.0 192000.0 0.86 660147.0 132000.0 0.66 1.073 0.991 1973905 ChemDiv1_007563 COc1cccc(c1)C2=NN(C(=O)c3ccc(Cl)cc3)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H18 compound treatment 704359.0 126000.0 0.57 609116.0 81500.0 0.4 0.6849 0.9864 1670131 ChemDiv1_007564 COc1cccc(c1)c2nc3sc4CCCCc4c3c(=O)n2CC(=O)Nc5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H19 compound treatment 734606.0 156000.0 0.7 639803.0 112000.0 0.56 0.8881 0.9934 1389391 ChemDiv1_007565 Cn1c(=O)n(C)c2nc(SCC(=O)Nc3ccc4OCOc4c3)n(Cc5ccccc5)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H20 compound treatment 692360.0 114000.0 0.51 582590.0 54900.0 0.27 0.554 0.9564 1617405 ChemDiv1_007566 CCOC(=O)c1sc2nc(C)nc(NCCC3=CCCCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H21 compound treatment 736648.0 159000.0 0.71 609547.0 81900.0 0.41 0.7886 0.9648 1973906 ChemDiv1_007567 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)ccc1OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H22 compound treatment 699523.0 121000.0 0.54 587296.0 59600.0 0.3 0.5932 0.959 1687239 ChemDiv1_007568 COc1cc(cc(OC)c1OC)c2nc(NC3CCCCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H23 mock treatment 654796.0 76700.0 0.34 573183.0 45500.0 0.23 0.4021 0.9792 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 H24 mock treatment 496894.0 -81200.0 -0.36 432563.0 -95100.0 -0.47 -0.5902 -0.9918 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I01 compound treatment 643868.0 65700.0 0.29 579825.0 52200.0 0.26 0.3908 0.9979 1973907 ChemDiv1_007569 CCOc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(O)c(c3)C(=O)O)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I02 compound treatment 721456.0 143000.0 0.64 572132.0 44500.0 0.22 0.6095 0.8984 1973908 ChemDiv1_007570 Cc1ccc(F)cc1NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I03 compound treatment 708585.0 130000.0 0.58 583905.0 56200.0 0.28 0.61 0.9427 1973909 ChemDiv1_007571 CC/N=C/1\SC(CC(=O)Nc2ccc(cc2)C(F)(F)F)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I04 compound treatment 709054.0 131000.0 0.59 586525.0 58900.0 0.29 0.6206 0.9481 1392460 ChemDiv1_007572 COC(=O)C1=C(C)NC2=C(C1c3ccc(OCc4ccc(Cl)cc4)c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I05 compound treatment 720540.0 142000.0 0.64 621948.0 94300.0 0.47 0.7811 0.9883 1187995 ChemDiv1_007573 COC(=O)C(C)OC(=O)c1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I06 compound treatment 701660.0 124000.0 0.55 611049.0 83400.0 0.41 0.6831 0.9897 1973910 ChemDiv1_007574 ClC1=CCC2C(C1)C(=O)N(CN3CCN(CN4C(=O)C5CC=C(Cl)CC5C4=O)CC3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I07 compound treatment 782802.0 205000.0 0.92 648398.0 121000.0 0.6 1.0708 0.9786 1523222 ChemDiv1_007575 COc1cc(ccc1O)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I08 compound treatment 776957.0 199000.0 0.89 614063.0 86400.0 0.43 0.932 0.9437 1557475 ChemDiv1_007576 O=C(Nc1ccccn1)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I09 compound treatment 731831.0 154000.0 0.69 657734.0 130000.0 0.64 0.9422 0.9995 1932962 ChemDiv1_007577 CC(=C)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC(=C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I10 compound treatment 771225.0 193000.0 0.86 644552.0 117000.0 0.58 1.0207 0.981 1155139 ChemDiv1_007578 COc1ccc(cc1)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I11 compound treatment 744338.0 166000.0 0.74 655206.0 128000.0 0.63 0.9729 0.9967 1546150 ChemDiv1_007579 Cc1ccc2N(C(=O)CSc3nc4ccccc4o3)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I12 compound treatment 751831.0 174000.0 0.78 666121.0 138000.0 0.69 1.0348 0.998 1973911 ChemDiv1_007580 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I13 compound treatment 749024.0 171000.0 0.77 652273.0 125000.0 0.62 0.9774 0.9943 1417836 ChemDiv1_007581 Cn1cnnc1SCC(=O)N2c3ccccc3CCc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I14 compound treatment 777691.0 200000.0 0.89 646028.0 118000.0 0.59 1.0463 0.9792 1587367 ChemDiv1_007582 Cc1ccc(cc1)N2C(=O)C3C(C2=O)C4(OC3(C)C=C4)C5OCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I15 compound treatment 806832.0 229000.0 1.02 664570.0 137000.0 0.68 1.2035 0.98 1973912 ChemDiv1_007583 COc1cc(ccc1OCCOCCOc2ccccc2C)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I16 compound treatment 766422.0 188000.0 0.84 652340.0 125000.0 0.62 1.0328 0.9883 1493008 ChemDiv1_007584 Cc1cc(ccc1Cl)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I17 compound treatment 741524.0 163000.0 0.73 658605.0 131000.0 0.65 0.9759 0.9982 1973913 ChemDiv1_007585 CCC([N+](=O)[O-])C1(O)C(=O)Nc2ccccc21 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I18 compound treatment 765218.0 187000.0 0.84 661708.0 134000.0 0.66 1.0618 0.9934 1973914 ChemDiv1_007586 CC(C)(C)c1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I19 compound treatment 745189.0 167000.0 0.75 652203.0 125000.0 0.62 0.9651 0.9954 1204438 ChemDiv1_007587 CCCOc1ccc(cc1)C(=O)Nc2cccc(c3nc4ccccc4[nH]3)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I20 compound treatment 712758.0 135000.0 0.6 632849.0 105000.0 0.52 0.7946 0.9974 1625724 ChemDiv1_007588 CC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I21 compound treatment 746948.0 169000.0 0.76 640445.0 113000.0 0.56 0.9294 0.989 1973915 ChemDiv1_007589 OC(=O)c1ccc2[nH]c(=O)c(Cc3ccc(OC(F)F)cc3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I22 compound treatment 697687.0 120000.0 0.54 604612.0 77000.0 0.38 0.648 0.9862 1941159 ChemDiv1_007590 CCOC(=O)C1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I23 mock treatment 674235.0 96100.0 0.43 609016.0 81400.0 0.4 0.5892 0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 I24 mock treatment 514589.0 -63500.0 -0.28 528516.0 855.0 0.0 -0.1981 -0.6965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J01 compound treatment 611952.0 33800.0 0.15 528067.0 406.0 0.0 0.1085 0.7164 1951261 ChemDiv1_007591 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J02 compound treatment 660992.0 82900.0 0.37 529819.0 2160.0 0.01 0.2699 0.7272 1514625 ChemDiv1_007592 Cn1c(N)c(C(=O)CSc2ncnc3[nH]cnc23)c(=O)n(C)c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J03 compound treatment 691006.0 113000.0 0.51 559885.0 32200.0 0.16 0.4702 0.8873 1973916 ChemDiv1_007593 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J04 compound treatment 688407.0 110000.0 0.49 572815.0 45200.0 0.22 0.5072 0.9359 1973917 ChemDiv1_007594 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(C)cc4c3=O)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J05 compound treatment 701436.0 123000.0 0.55 572615.0 45000.0 0.22 0.5478 0.9203 1951412 ChemDiv1_007595 OC1(CC(=NN1C(=O)c2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J06 compound treatment 696181.0 118000.0 0.53 600357.0 72700.0 0.36 0.6283 0.9825 1973918 ChemDiv1_007596 CC/1=NN(C(=O)\C1=C/Nc2c(C)[nH]n(c3ccccc3)c2=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J07 compound treatment 740607.0 162000.0 0.73 655433.0 128000.0 0.63 0.9619 0.9976 1931115 ChemDiv1_007597 Cc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J08 compound treatment 738644.0 161000.0 0.72 633518.0 106000.0 0.52 0.8789 0.988 1669784 ChemDiv1_007598 Fc1ccc(cc1)N2CCN(CC2)C(=O)Cn3c(nc4ccccc4c3=O)c5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J09 compound treatment 727351.0 149000.0 0.67 650050.0 122000.0 0.61 0.9011 0.9988 1476117 ChemDiv1_007599 CCC1=NN(C(=O)Cc2ccccc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J10 compound treatment 678970.0 101000.0 0.45 635684.0 108000.0 0.54 0.6976 0.9964 1973919 ChemDiv1_007600 Cc1cc2nc(Cc3ccc(OC(F)F)cc3)c(=O)n(C)c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J11 compound treatment 777997.0 200000.0 0.89 685244.0 158000.0 0.78 1.1846 0.9977 1973920 ChemDiv1_007601 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)c3ccc(Br)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J12 compound treatment 730623.0 152000.0 0.68 636226.0 109000.0 0.54 0.863 0.993 1315135 ChemDiv1_007602 CCOC(=O)c1sc2nc(C)nc(N3CCCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J13 compound treatment 721591.0 143000.0 0.64 642444.0 115000.0 0.57 0.8562 0.9982 1948828 ChemDiv1_007603 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J14 compound treatment 751159.0 173000.0 0.77 630216.0 103000.0 0.51 0.9069 0.9791 1973921 ChemDiv1_007604 FC(F)(F)c1cccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J15 compound treatment 734741.0 157000.0 0.7 642526.0 115000.0 0.57 0.8981 0.9946 1973922 ChemDiv1_007605 COc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J16 compound treatment 711118.0 133000.0 0.6 636213.0 109000.0 0.54 0.8012 0.9987 1973923 ChemDiv1_007606 O=C(Cn1c(Cc2ccccc2)nc3sc4CCCCc4c3c1=O)Nc5ccc(Oc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J17 compound treatment 709033.0 131000.0 0.59 645181.0 118000.0 0.58 0.826 1.0 1289604 ChemDiv1_007607 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J18 compound treatment 728224.0 150000.0 0.67 635781.0 108000.0 0.54 0.8538 0.9937 1656327 ChemDiv1_007608 COc1ccc(CCNC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J19 compound treatment 744676.0 167000.0 0.75 634318.0 107000.0 0.53 0.9008 0.9858 1973924 ChemDiv1_007609 CCC(=O)n1cc(/C=C/2\S/C(=N\C)/N(C)C2=O)c(n1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J20 compound treatment 712969.0 135000.0 0.6 605641.0 78000.0 0.39 0.7 0.9767 1706081 ChemDiv1_007610 CCOC(=O)c1sc2nc(C)nc(NCc3ccc4OCOc4c3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J21 compound treatment 713569.0 135000.0 0.61 599131.0 71500.0 0.35 0.6791 0.9672 1973925 ChemDiv1_007611 CCCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)C(=O)OC(C)C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J22 compound treatment 699143.0 121000.0 0.54 592999.0 65300.0 0.32 0.6119 0.9697 1276303 ChemDiv1_007612 COc1cc(cc(OC)c1OC)c2nc(NCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J23 mock treatment 664364.0 86200.0 0.39 584315.0 56700.0 0.28 0.4714 0.9877 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 J24 mock treatment 495460.0 -82700.0 -0.37 527031.0 -630.0 0.0 -0.2639 -0.713 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K01 compound treatment 632546.0 54400.0 0.24 543978.0 16300.0 0.08 0.2294 0.8938 1973926 ChemDiv1_007613 NS(=O)(=O)c1ccc(NC(=O)CCCN2C(=O)S/C(=C/C=C/c3ccccc3)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K02 compound treatment 680705.0 103000.0 0.46 549327.0 21700.0 0.11 0.4006 0.8495 1973927 ChemDiv1_007614 Clc1ccc2n(CC(=O)N3CCN(CC3)c4ccccc4)c5ccccc5c(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K03 compound treatment 687147.0 109000.0 0.49 625185.0 97500.0 0.48 0.6867 1.0 1973928 ChemDiv1_007615 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K04 compound treatment 694538.0 116000.0 0.52 585187.0 57500.0 0.28 0.57 0.9597 1973929 ChemDiv1_007616 COC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K05 compound treatment 691620.0 113000.0 0.51 621804.0 94100.0 0.47 0.689 0.9991 1163202 ChemDiv1_007617 COC(=O)c1ccc(Oc2nc(SC)nc(n2)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K06 compound treatment 731904.0 154000.0 0.69 605413.0 77800.0 0.39 0.7591 0.9624 1973930 ChemDiv1_007618 CC(CN1C(=O)C2C(C3C2C4C=CC3C5C4C(=O)N(CC(C)c6ccccc6)C5=O)C1=O)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K07 compound treatment 766446.0 188000.0 0.84 608249.0 80600.0 0.4 0.8784 0.9417 1269746 ChemDiv1_007619 CCOc1cc(ccc1O)C2Nc3ccc(cc3NC4=C2C(=O)CC(C)(C)C4)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K08 compound treatment 647589.0 69500.0 0.31 632181.0 105000.0 0.52 0.586 0.9702 1599859 ChemDiv1_007620 COc1cccc(C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K09 compound treatment 794206.0 216000.0 0.97 712363.0 185000.0 0.91 1.3309 0.9996 1515055 ChemDiv1_007621 CCOC(=O)CSc1nc2sc3CN(C)CCc3c2c(=O)n1Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K10 compound treatment 737741.0 160000.0 0.71 618135.0 90500.0 0.45 0.8222 0.9748 1973931 ChemDiv1_007622 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K11 compound treatment 751094.0 173000.0 0.77 671252.0 144000.0 0.71 1.0505 0.9991 1707885 ChemDiv1_007623 O=C(CSc1nc2ccccc2o1)n3c4ccccc4c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K12 compound treatment 757712.0 180000.0 0.8 658169.0 131000.0 0.65 1.0256 0.9942 1296739 ChemDiv1_007624 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCC(=O)O)c4cccs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K13 compound treatment 742922.0 165000.0 0.74 639409.0 112000.0 0.55 0.9131 0.99 1669756 ChemDiv1_007625 COc1ccc2N(C(=O)CSc3nnc(C)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K14 compound treatment 714124.0 136000.0 0.61 647828.0 120000.0 0.6 0.8514 0.9999 1697207 ChemDiv1_007626 O=C1N(CN2CCCCC2)c3ccccc3C41OCCCO4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K15 compound treatment 780205.0 202000.0 0.9 683046.0 155000.0 0.77 1.1839 0.9968 1973932 ChemDiv1_007627 COc1cccc(OCCOc2c(Cl)cc(cc2OC)c3nc4sc5CCCCc5c4c(=O)[nH]3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K16 compound treatment 721337.0 143000.0 0.64 642136.0 114000.0 0.57 0.8543 0.9981 1476098 ChemDiv1_007628 Cc1ccc(cc1C)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K17 compound treatment 760250.0 182000.0 0.82 681926.0 154000.0 0.76 1.1169 0.9995 1303983 ChemDiv1_007629 OC1(CC(=O)c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K18 compound treatment 685712.0 108000.0 0.48 644057.0 116000.0 0.58 0.7483 0.996 1973933 ChemDiv1_007630 OC1(CC(=NN1C(=O)CCCc2ccccc2)c3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K19 compound treatment 774749.0 197000.0 0.88 659104.0 131000.0 0.65 1.0828 0.989 1973934 ChemDiv1_007631 Cc1c(NC(=O)c2cccc([N+](=O)[O-])c2C)cccc1c3nc4ccccc4[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K20 compound treatment 678488.0 100000.0 0.45 710715.0 183000.0 0.91 0.9589 0.9475 1517705 ChemDiv1_007632 CC1=NN(C(=O)c2cccc(O)c2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K21 compound treatment 696634.0 119000.0 0.53 649022.0 121000.0 0.6 0.8002 0.9981 1973935 ChemDiv1_007633 Clc1ccc(NC(=O)Cn2c3ccccc3c(=O)c4ccc(Cl)cc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K22 compound treatment 695790.0 118000.0 0.53 626480.0 98800.0 0.49 0.7186 0.9993 1973936 ChemDiv1_007634 CCOC(=O)C1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K23 mock treatment 671462.0 93300.0 0.42 617807.0 90100.0 0.45 0.6112 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 K24 mock treatment 519735.0 -58400.0 -0.26 525960.0 -1700.0 -0.01 -0.1908 -0.7295 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L01 compound treatment 611708.0 33600.0 0.15 529760.0 2100.0 0.01 0.1137 0.7542 1973937 ChemDiv1_007635 OC1(CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L02 compound treatment 643610.0 65500.0 0.29 544101.0 16400.0 0.08 0.2649 0.8706 1427755 ChemDiv1_007636 C(N1CCCCC1)n2c3ccccc3c4nc5ccccc5nc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L03 compound treatment 668944.0 90800.0 0.41 584553.0 56900.0 0.28 0.4868 0.984 1951195 ChemDiv1_007637 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L04 compound treatment 696383.0 118000.0 0.53 561442.0 33800.0 0.17 0.4927 0.8874 1423415 ChemDiv1_007638 CCC(=O)Nc1nc2CC(C)(C)CC(=O)c2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L05 compound treatment 716308.0 138000.0 0.62 595720.0 68100.0 0.34 0.6758 0.9593 1929125 ChemDiv1_007639 CC(C)(C)c1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L06 compound treatment 682419.0 104000.0 0.47 596748.0 69100.0 0.34 0.5721 0.9883 1021801 ChemDiv1_007640 CSc1nc(N)nc2[nH]cnc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L07 compound treatment 694373.0 116000.0 0.52 606063.0 78400.0 0.39 0.6426 0.9896 1948700 ChemDiv1_007641 OC1(CC(=NN1C(=O)CCc2ccccc2)c3ccc(Cl)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L08 compound treatment 826518.0 248000.0 1.11 679410.0 152000.0 0.75 1.3178 0.9818 1973938 ChemDiv1_007642 CCOC(=O)N1CCC(CC1)NC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L09 compound treatment 689248.0 111000.0 0.5 639455.0 112000.0 0.55 0.7433 0.9986 1779844 ChemDiv1_007643 CCC1=NN(C(=O)Cc2ccc(cc2)[N+](=O)[O-])C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L10 compound treatment 695619.0 117000.0 0.53 612399.0 84700.0 0.42 0.6687 0.9938 1973939 ChemDiv1_007644 Cc1sc2nc(c3ccccc3Cl)n(CC(=O)Nc4ccc(C)c(Cl)c4)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L11 compound treatment 724893.0 147000.0 0.66 653542.0 126000.0 0.62 0.9055 0.9997 1929049 ChemDiv1_007645 OC1(CC(=NN1C(=O)Cc2ccc(cc2)[N+](=O)[O-])c3ccc(Br)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L12 compound treatment 711785.0 134000.0 0.6 640253.0 113000.0 0.56 0.8175 0.9994 1973940 ChemDiv1_007646 CCOC(=O)c1sc(NC(=O)Cn2cnc3ccccc3c2=O)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L13 compound treatment 698530.0 120000.0 0.54 658331.0 131000.0 0.65 0.8388 0.9959 1973941 ChemDiv1_007647 OC1(CC(=NN1C(=O)c2ccncc2)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L14 compound treatment 706800.0 129000.0 0.58 654774.0 127000.0 0.63 0.8526 0.999 1575867 ChemDiv1_007648 Cc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L15 compound treatment 701802.0 124000.0 0.55 665216.0 138000.0 0.68 0.8733 0.9947 1929068 ChemDiv1_007649 COc1cccc(c1)C2=NN(C(=O)Cc3ccccc3)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L16 compound treatment 719272.0 141000.0 0.63 641684.0 114000.0 0.56 0.8462 0.9984 1351746 ChemDiv1_007650 COc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L17 compound treatment 745211.0 167000.0 0.75 666310.0 139000.0 0.69 1.0145 0.9991 1183225 ChemDiv1_007651 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(C)cc(C)n3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L18 compound treatment 694419.0 116000.0 0.52 621512.0 93900.0 0.46 0.6969 0.9984 1547864 ChemDiv1_007652 Brc1cccc(Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L19 compound treatment 723208.0 145000.0 0.65 628947.0 101000.0 0.5 0.814 0.9919 1177977 ChemDiv1_007653 CCC(=O)Nc1nc2[nH]c(cc(=O)n2n1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L20 compound treatment 695174.0 117000.0 0.52 624865.0 97200.0 0.48 0.711 0.9991 1288085 ChemDiv1_007654 CCOC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L21 compound treatment 704869.0 127000.0 0.57 632061.0 104000.0 0.52 0.7669 0.9989 1232212 ChemDiv1_007655 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L22 compound treatment 684190.0 106000.0 0.47 617387.0 89700.0 0.44 0.65 0.9995 1739639 ChemDiv1_007656 COC(=O)c1cc(Nc2nc(nc3ccccc23)c4cc(OC)c(OC)c(OC)c4)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L23 mock treatment 647758.0 69600.0 0.31 591324.0 63700.0 0.32 0.4434 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 L24 mock treatment 482165.0 -96000.0 -0.43 505730.0 -21900.0 -0.11 -0.3806 -0.8589 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M01 compound treatment 629595.0 51500.0 0.23 554205.0 26500.0 0.13 0.2559 0.9646 1973942 ChemDiv1_007657 CCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M02 compound treatment 636003.0 57900.0 0.26 570958.0 43300.0 0.21 0.3349 0.9956 1973943 ChemDiv1_007658 Fc1ccc(CNC(=O)Cn2c3ccccc3c(=O)c4cc(Cl)ccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M03 compound treatment 1190596.0 612000.0 2.74 1000529.0 473000.0 2.34 3.595 0.9969 1973944 ChemDiv1_007659 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(CC=C)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M04 compound treatment 679722.0 102000.0 0.45 593218.0 65600.0 0.32 0.5512 0.9864 1973945 ChemDiv1_007660 CCOc1ccccc1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M05 compound treatment 707459.0 129000.0 0.58 609244.0 81600.0 0.4 0.6952 0.9846 1240730 ChemDiv1_007661 COC(=O)COC(=O)c1ccc(Oc2nc(OC)nc(n2)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M06 compound treatment 706485.0 128000.0 0.57 584305.0 56600.0 0.28 0.6047 0.9457 1703966 ChemDiv1_007662 O=C(N1CCOCC1)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M07 compound treatment 743735.0 166000.0 0.74 658438.0 131000.0 0.65 0.9823 0.9977 1973946 ChemDiv1_007663 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4ccc(cc4)[N+](=O)[O-])C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M08 compound treatment 770303.0 192000.0 0.86 689731.0 162000.0 0.8 1.176 0.9994 1532753 ChemDiv1_007664 COc1ccc(cc1)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M09 compound treatment 695555.0 117000.0 0.53 679785.0 152000.0 0.75 0.9046 0.9845 1973947 ChemDiv1_007665 CCC1(C)Cc2c(CO1)sc3nc(SCC(=O)OC)n(Cc4ccccc4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M10 compound treatment 741786.0 164000.0 0.73 693170.0 166000.0 0.82 1.0978 0.9984 1973948 ChemDiv1_007666 COc1ccccc1C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M11 compound treatment 716570.0 138000.0 0.62 671420.0 144000.0 0.71 0.9418 0.9976 1307335 ChemDiv1_007667 CCOc1ccc2N(C(=O)CSc3nnc[nH]3)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M12 compound treatment 730690.0 153000.0 0.68 662904.0 135000.0 0.67 0.9567 1.0 1156043 ChemDiv1_007668 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCCC(=O)O)c4cccs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M13 compound treatment 716814.0 139000.0 0.62 676613.0 149000.0 0.74 0.9608 0.9963 1329688 ChemDiv1_007669 CCOc1ccc2N(C(=O)CSc3nnc(C)s3)C(C)(C)c4ssc(=S)c4-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M14 compound treatment 714437.0 136000.0 0.61 665271.0 138000.0 0.68 0.9135 0.9985 1293822 ChemDiv1_007670 OC1(C2CCCC(C2=O)C3(O)C(=O)Nc4ccccc43)C(=O)Nc5ccccc51 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M15 compound treatment 712084.0 134000.0 0.6 689968.0 162000.0 0.8 0.9926 0.9896 1973949 ChemDiv1_007671 COc1cc(ccc1OCCOCCOc2ccc(C)c(C)c2)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M16 compound treatment 708351.0 130000.0 0.58 660571.0 133000.0 0.66 0.8778 0.9982 1973950 ChemDiv1_007672 CCC1=NN(C(=O)c2cccc(Br)c2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M17 compound treatment 745281.0 167000.0 0.75 685565.0 158000.0 0.78 1.0822 0.9998 1304737 ChemDiv1_007673 OC1(CC(=O)c2ccc3CCCCc3c2)C(=O)Nc4ccc(Br)cc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M18 compound treatment 731532.0 153000.0 0.69 662553.0 135000.0 0.67 0.9581 0.9999 1973951 ChemDiv1_007674 CCCCC1=NN(C(=O)COc2ccccc2C)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M19 compound treatment 755416.0 177000.0 0.79 680647.0 153000.0 0.76 1.0971 0.9997 1973952 ChemDiv1_007675 Cn1c(SCc2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])nc5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M20 compound treatment 717827.0 140000.0 0.63 663286.0 136000.0 0.67 0.9173 0.9994 1683145 ChemDiv1_007676 COc1ccc(cc1)C(=O)N2N=C(C)CC2(O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M21 compound treatment 719503.0 141000.0 0.63 680268.0 153000.0 0.76 0.9821 0.9961 1503056 ChemDiv1_007677 CCOC(=O)c1nc(Nc2ccc(OC)cc2Cl)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M22 compound treatment 695043.0 117000.0 0.52 629155.0 101000.0 0.5 0.7256 0.9998 1701386 ChemDiv1_007678 CCOC(=O)C1=NN(C(=O)COc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M23 mock treatment 660363.0 82200.0 0.37 627988.0 100000.0 0.5 0.6117 0.9891 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 M24 mock treatment 524775.0 -53300.0 -0.24 407480.0 -120000.0 -0.6 -0.5898 -0.9195 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N01 compound treatment 593806.0 15700.0 0.07 528452.0 791.0 0.0 0.0524 0.7454 1929030 ChemDiv1_007679 COc1cccc(c1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N02 compound treatment 623924.0 45800.0 0.21 556096.0 28400.0 0.14 0.2446 0.9832 1593944 ChemDiv1_007680 C(N1CCOCC1)n2c3ccccc3c4nc5ccccc5nc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N03 compound treatment 686654.0 109000.0 0.49 567275.0 39600.0 0.2 0.4823 0.9205 1948880 ChemDiv1_007681 C/C(=C\C(=O)C(F)(F)F)/Nc1ccc(cc1)C(=O)N2N=C(C)CC2(O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N04 compound treatment 621492.0 43400.0 0.19 574213.0 46600.0 0.23 0.3003 0.9963 1328098 ChemDiv1_007682 COc1cc(C)nc(n1)N(CCC(C)C)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N05 compound treatment 691501.0 113000.0 0.51 575257.0 47600.0 0.24 0.5256 0.9392 1929023 ChemDiv1_007683 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N06 compound treatment 697954.0 120000.0 0.54 602009.0 74300.0 0.37 0.6397 0.9832 1718351 ChemDiv1_007684 Cc1ccc2nsnc2c1NC(=O)c3ccc4OCCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N07 compound treatment 714394.0 136000.0 0.61 609401.0 81700.0 0.4 0.7177 0.9802 1579384 ChemDiv1_007685 COc1ccc(CC(=O)N2N=C(C)CC2(O)c3ccc(Cl)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N08 compound treatment 687931.0 110000.0 0.49 621328.0 93700.0 0.46 0.6757 0.9996 1427928 ChemDiv1_007686 Cc1cc2nc(Cc3ccc(F)c(F)c3)c(=O)n(C)c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N09 compound treatment 702267.0 124000.0 0.56 654690.0 127000.0 0.63 0.8379 0.9981 1517402 ChemDiv1_007687 CCC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N10 compound treatment 693798.0 116000.0 0.52 652459.0 125000.0 0.62 0.8033 0.9961 1547297 ChemDiv1_007688 COc1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccc(C)cc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N11 compound treatment 654357.0 76200.0 0.34 646279.0 119000.0 0.59 0.6568 0.9666 1939182 ChemDiv1_007689 OC1(CC(=NN1C(=O)Cc2ccccc2)c3ccc(Br)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N12 compound treatment 668629.0 90500.0 0.41 645389.0 118000.0 0.58 0.6989 0.9842 1252722 ChemDiv1_007690 CCOC(=O)c1sc2nc(C)nc(Nc3ccc(OC)cc3OC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N13 compound treatment 724202.0 146000.0 0.65 665409.0 138000.0 0.68 0.9449 0.9998 1973953 ChemDiv1_007691 Cc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N14 compound treatment 637874.0 59800.0 0.27 653856.0 126000.0 0.63 0.6312 0.9282 1457913 ChemDiv1_007692 Cc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N15 compound treatment 702600.0 124000.0 0.56 663661.0 136000.0 0.67 0.8704 0.9955 1951819 ChemDiv1_007693 COc1cccc(c1)C2=NN(C(=O)c3cccc(c3)[N+](=O)[O-])C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N16 compound treatment 701741.0 124000.0 0.55 656646.0 129000.0 0.64 0.8431 0.9974 1179871 ChemDiv1_007694 CCOC(=O)c1sc2nc(C)nc(OCc3ccccc3Cl)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N17 compound treatment 732359.0 154000.0 0.69 672660.0 145000.0 0.72 0.9961 0.9998 1683227 ChemDiv1_007695 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nccn3C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N18 compound treatment 716037.0 138000.0 0.62 646989.0 119000.0 0.59 0.8545 0.9998 1175410 ChemDiv1_007696 Clc1ccccc1NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N19 compound treatment 708528.0 130000.0 0.58 663159.0 135000.0 0.67 0.8874 0.9976 1973954 ChemDiv1_007697 COC(=O)c1ccc(cc1)N2N=C(C)/C(=C/c3ccc(o3)c4cccc(c4)C(=O)O)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N20 compound treatment 699041.0 121000.0 0.54 643121.0 115000.0 0.57 0.7872 0.9996 1973955 ChemDiv1_007698 CCOC(=O)c1sc2nc(C)nc(NCCCN3CCOCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N21 compound treatment 709476.0 131000.0 0.59 626317.0 98700.0 0.49 0.7613 0.9958 1196056 ChemDiv1_007699 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N22 compound treatment 638326.0 60200.0 0.27 601015.0 73400.0 0.36 0.4475 0.9892 1497498 ChemDiv1_007700 COc1cc(cc(OC)c1OC)c2nc(N3CCN(C)CC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N23 mock treatment 661142.0 83000.0 0.37 603640.0 76000.0 0.38 0.5289 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 N24 mock treatment 499511.0 -78600.0 -0.35 389400.0 -138000.0 -0.68 -0.7331 -0.9521 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O01 compound treatment 602856.0 24700.0 0.11 542135.0 14500.0 0.07 0.129 0.9779 1973956 ChemDiv1_007701 CCC1S/C(=N/c2ccccc2)/N(C1=O)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O02 compound treatment 635747.0 57600.0 0.26 547416.0 19800.0 0.1 0.2516 0.912 1251746 ChemDiv1_007702 Cn1c(=O)c(Cc2ccccc2Cl)nc3cc(ccc13)C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O03 compound treatment 673120.0 95000.0 0.43 591962.0 64300.0 0.32 0.5259 0.9899 1371125 ChemDiv1_007703 Cc1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O04 compound treatment 632899.0 54800.0 0.25 553671.0 26000.0 0.13 0.2645 0.9549 1973957 ChemDiv1_007704 CCOC(=O)C1=C(N)OC2=C(C1c3cc([N+](=O)[O-])c(C)s3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O05 compound treatment 693748.0 116000.0 0.52 583905.0 56200.0 0.28 0.563 0.9578 1380249 ChemDiv1_007705 COc1nc(Oc2ccc(cc2)C(=O)OCC(=O)N)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O06 compound treatment 685727.0 108000.0 0.48 561367.0 33700.0 0.17 0.4587 0.8997 1534647 ChemDiv1_007706 CN1CCN(CC1)C(=O)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O07 compound treatment 682849.0 105000.0 0.47 606307.0 78600.0 0.39 0.607 0.9958 1784490 ChemDiv1_007707 CC1(C)CC(=O)C2=C(C1)Nc3cc(ccc3NC2c4cccc(c4)[N+](=O)[O-])C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O08 compound treatment 680536.0 102000.0 0.46 615003.0 87300.0 0.43 0.6301 0.9996 1742218 ChemDiv1_007708 COc1cccc(C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(Br)cc3)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O09 compound treatment 678311.0 100000.0 0.45 645898.0 118000.0 0.59 0.7313 0.9913 1940927 ChemDiv1_007709 CCCCN(CN1C(=O)C2CC=C(Cl)CC2C1=O)CN3C(=O)C4CC=C(Cl)CC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O10 compound treatment 655384.0 77300.0 0.35 629821.0 102000.0 0.51 0.6024 0.9828 1973958 ChemDiv1_007710 COc1ccc(cc1)C2=NN(C(C2)c3cc(OC)ccc3OC)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O11 compound treatment 680517.0 102000.0 0.46 654890.0 127000.0 0.63 0.7698 0.9878 1279536 ChemDiv1_007711 O=C(CSc1nnc[nH]1)n2c3CCCCc3c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O12 compound treatment 688496.0 110000.0 0.49 643657.0 116000.0 0.57 0.7557 0.9972 1294923 ChemDiv1_007712 OC(=O)CCCC(=O)N1N=C(CC1c2ccccc2F)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O13 compound treatment 727171.0 149000.0 0.67 682781.0 155000.0 0.77 1.0151 0.9975 1973959 ChemDiv1_007713 [O-][N+](=O)c1ccc(c2ccc(o2)c3nc4sc5CCCCc5c4c(=O)[nH]3)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O14 compound treatment 686033.0 108000.0 0.48 630261.0 103000.0 0.51 0.701 0.9997 1195752 ChemDiv1_007714 CCC1CCC(=O)C(C1)C2(O)C(=O)Nc3ccccc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O15 compound treatment 722629.0 145000.0 0.65 685911.0 158000.0 0.78 1.0117 0.9954 1973960 ChemDiv1_007715 CCOc1cc(ccc1OCCOCCOc2ccccc2C)c3nc4sc5CCCCc5c4c(=O)[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O16 compound treatment 676362.0 98200.0 0.44 655785.0 128000.0 0.63 0.7598 0.9839 1973961 ChemDiv1_007716 CCC1=NN(C(=O)Cc2ccc(OC)c(OC)c2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O17 compound treatment 665795.0 87700.0 0.39 695348.0 168000.0 0.83 0.8649 0.9414 1715441 ChemDiv1_007717 CC(C(=O)c1ccccc1)C2(O)C(=O)Nc3ccc(Br)cc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O18 compound treatment 680369.0 102000.0 0.46 646937.0 119000.0 0.59 0.7414 0.992 1973962 ChemDiv1_007718 CCCCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O19 compound treatment 705833.0 128000.0 0.57 665956.0 138000.0 0.69 0.8887 0.996 1973963 ChemDiv1_007719 FC(F)(F)c1cccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O20 compound treatment 664772.0 86600.0 0.39 628434.0 101000.0 0.5 0.6273 0.9922 1927750 ChemDiv1_007720 CC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O21 compound treatment 690289.0 112000.0 0.5 662004.0 134000.0 0.67 0.8256 0.9903 1156166 ChemDiv1_007721 CCOC(=O)c1nc(Nc2ccc3CCCc3c2)c4ccccc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O22 compound treatment 647150.0 69000.0 0.31 602622.0 75000.0 0.37 0.4811 0.9958 1386793 ChemDiv1_007722 CCOC(=O)C1=NN(C(=O)CCc2ccccc2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O23 mock treatment 626337.0 48200.0 0.22 601754.0 74100.0 0.37 0.4121 0.968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 O24 mock treatment 406600.0 -172000.0 -0.77 241213.0 -286000.0 -1.42 -1.5463 -0.9584 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P01 compound treatment 568907.0 -9220.0 -0.04 524870.0 -2790.0 -0.01 -0.0389 -0.8951 1948577 ChemDiv1_007723 OC1(CC(=NN1C(=O)c2ccncc2)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P02 compound treatment 605304.0 27200.0 0.12 532733.0 5070.0 0.03 0.1038 0.8355 1515753 ChemDiv1_007724 CCOC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P03 compound treatment 586097.0 7970.0 0.04 541351.0 13700.0 0.07 0.0732 0.9551 1973964 ChemDiv1_007725 CCCC1=NN(C(=O)c2ccc(cc2)C(C)(C)C)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P04 compound treatment 604358.0 26200.0 0.12 555251.0 27600.0 0.14 0.1797 0.9971 1973965 ChemDiv1_007726 CCOC(=O)c1c(NC(=O)CC2S/C(=N/C)/N(C)C2=O)sc3CCCCc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P05 compound treatment 631370.0 53200.0 0.24 547460.0 19800.0 0.1 0.2379 0.923 1948910 ChemDiv1_007727 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P06 compound treatment 618642.0 40500.0 0.18 564567.0 36900.0 0.18 0.2575 1.0 1253147 ChemDiv1_007728 O=C(N1C(=O)c2ccccc2S1(=O)=O)c3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P07 compound treatment 660372.0 82200.0 0.37 590784.0 63100.0 0.31 0.4815 0.9967 1574959 ChemDiv1_007729 CC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P08 compound treatment 646985.0 68900.0 0.31 577036.0 49400.0 0.24 0.3909 0.9934 1547213 ChemDiv1_007730 COc1ccc(NC(=O)Cn2c(nc3sc(C)c(C)c3c2=O)c4ccccc4Cl)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P09 compound treatment 666891.0 88800.0 0.4 588611.0 61000.0 0.3 0.4945 0.9908 1169643 ChemDiv1_007731 CCC1=NN(C(=O)c2cccc(OC)c2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P10 compound treatment 642530.0 64400.0 0.29 573241.0 45600.0 0.23 0.3635 0.9927 1493554 ChemDiv1_007732 CN(C)c1ccc(NC(=O)Cn2c(nc3ccccc3c2=O)c4ccccc4F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P11 compound treatment 682163.0 104000.0 0.47 621532.0 93900.0 0.47 0.6581 1.0 1942893 ChemDiv1_007733 COc1ccc(cc1)C(=O)N2N=C(CC2(O)C(F)(F)F)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P12 compound treatment 650326.0 72200.0 0.32 564642.0 37000.0 0.18 0.3581 0.9638 1431171 ChemDiv1_007734 CCOC(=O)c1sc2nc(C)nc(Nc3cc(Cl)ccc3OC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P13 compound treatment 654810.0 76700.0 0.34 582330.0 54700.0 0.27 0.4342 0.9931 1973966 ChemDiv1_007735 OC1(CC(=NN1C(=O)COc2ccccc2)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P14 compound treatment 647376.0 69300.0 0.31 587503.0 59800.0 0.3 0.4288 0.9998 1683228 ChemDiv1_007736 CCOC(=O)c1sc2nc(C)n(CC(=O)Nc3ccc(OCC)cc3)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P15 compound treatment 677226.0 99100.0 0.44 620936.0 93300.0 0.46 0.6404 0.9998 1973967 ChemDiv1_007737 COc1cccc(c1)C2=NN(C(=O)c3ccccc3)C(O)(C2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P16 compound treatment 693155.0 115000.0 0.51 605090.0 77400.0 0.38 0.6353 0.9895 1639138 ChemDiv1_007738 COc1cccc(NC(=O)Cn2c(nc3sc4CCCCc4c3c2=O)c5cccc(OC)c5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P17 compound treatment 641714.0 63600.0 0.28 598495.0 70800.0 0.35 0.4494 0.9946 1529119 ChemDiv1_007739 O=C1CCCC2=C1C(C3=C(CCCC3=O)O2)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P18 compound treatment 684073.0 106000.0 0.47 600428.0 72800.0 0.36 0.5903 0.9908 1244524 ChemDiv1_007740 Fc1ccc(NC(=O)Cn2c(Cc3ccccc3)nc4sc5CCCCc5c4c2=O)c(F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P19 compound treatment 658039.0 79900.0 0.36 604271.0 76600.0 0.38 0.5213 0.9996 1973968 ChemDiv1_007741 COC(=O)c1ccc(cc1)N2N=C(C)/C(=C/c3ccc(o3)c4ccc(cc4)S(=O)(=O)N)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P20 compound treatment 648006.0 69900.0 0.31 596482.0 68800.0 0.34 0.4623 0.9991 1452350 ChemDiv1_007742 CCOC(=O)C1CCN(CC1)c2nc(nc3ccccc23)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P21 compound treatment 1170644.0 593000.0 2.65 1005398.0 478000.0 2.37 3.5489 0.9984 1480386 ChemDiv1_007743 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4ccc(OC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P22 compound treatment 623677.0 45600.0 0.2 584900.0 57200.0 0.28 0.3447 0.9869 1533549 ChemDiv1_007744 COc1cc(cc(OC)c1OC)c2nc(N3CCCC(C)C3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P23 mock treatment 582080.0 3960.0 0.02 565410.0 37700.0 0.19 0.1448 0.7706 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.608 P24 mock treatment 477213.0 -101000.0 -0.45 297734.0 -230000.0 -1.14 -1.1248 -0.918 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A01 compound treatment 593484.0 2140.0 0.01 531509.0 -88400.0 -0.44 -0.3028 -0.6915 1973969 ChemDiv1_007745 CCOC(=O)c1sc2nc(C)nc(NC3CCCCC3C)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A02 compound treatment 603848.0 12500.0 0.06 562247.0 -57600.0 -0.29 -0.1623 -0.5579 1161400 ChemDiv1_007746 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccccc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A03 compound treatment 621508.0 30200.0 0.14 573564.0 -46300.0 -0.23 -0.0668 -0.2509 1589242 ChemDiv1_007747 COc1cc(cc(OC)c1OC)c2nc(N3CCCCC3C)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A04 compound treatment 626057.0 34700.0 0.16 598882.0 -21000.0 -0.1 0.0363 0.194 1973970 ChemDiv1_007748 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCC(CC4)(N5CCCCC5)C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A05 compound treatment 636624.0 45300.0 0.2 588856.0 -31000.0 -0.15 0.0346 0.136 1973971 ChemDiv1_007749 CCOC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A06 compound treatment 668660.0 77300.0 0.35 614181.0 -5710.0 -0.03 0.2247 0.6472 1640109 ChemDiv1_007750 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A07 compound treatment 685932.0 94600.0 0.42 620070.0 179.0 0.0 0.3 0.7086 1235052 ChemDiv1_007751 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCc4cccs4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A08 compound treatment 687006.0 95700.0 0.43 625562.0 5670.0 0.03 0.3227 0.7519 1726292 ChemDiv1_007752 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A09 compound treatment 673530.0 82200.0 0.37 701818.0 81900.0 0.41 0.5471 0.9988 1242161 ChemDiv1_007753 COC(=O)Cc1nc(N2CCN(CC2)c3ccc(OC)cc3)c4c(C)c(C)sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A10 compound treatment 675042.0 83700.0 0.37 637667.0 17800.0 0.09 0.3272 0.8501 1286169 ChemDiv1_007754 CN(c1ccccc1)c2ncnc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A11 compound treatment 679602.0 88300.0 0.4 623810.0 3920.0 0.02 0.2931 0.741 1973972 ChemDiv1_007755 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3cc(OC)ccc3OC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A12 compound treatment 694383.0 103000.0 0.46 630603.0 10700.0 0.05 0.3637 0.7833 1399331 ChemDiv1_007756 COc1ccccc1N2CCN(CC2)c3ncnc4sc(C(=O)O)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A13 compound treatment 691521.0 100000.0 0.45 636792.0 16900.0 0.08 0.3763 0.8249 1973973 ChemDiv1_007757 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3cc(ccc3OC)[N+](=O)[O-])c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A14 compound treatment 674178.0 82800.0 0.37 652335.0 32400.0 0.16 0.3758 0.93 1973974 ChemDiv1_007758 Cc1c(sc2ncn(CC(=O)N3CCOCC3)c(=O)c12)C(=O)N4CCN(CC4)c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A15 compound treatment 701094.0 110000.0 0.49 648498.0 28600.0 0.14 0.4476 0.8754 1257391 ChemDiv1_007759 CCOC(=O)N1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A16 compound treatment 676471.0 85100.0 0.38 653232.0 33300.0 0.17 0.3862 0.93 1973975 ChemDiv1_007760 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A17 compound treatment 674522.0 83200.0 0.37 639706.0 19800.0 0.1 0.3327 0.864 1421175 ChemDiv1_007761 CCOC(=O)N1CCN(CC1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A18 compound treatment 669389.0 78000.0 0.35 635178.0 15300.0 0.08 0.3006 0.8409 1709068 ChemDiv1_007762 CCN(CC)c1ncnc2sc(C(=O)O)c(C)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A19 compound treatment 651239.0 59900.0 0.27 653108.0 33200.0 0.16 0.3059 0.9725 1290203 ChemDiv1_007763 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)O)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A20 compound treatment 621172.0 29800.0 0.13 624161.0 4270.0 0.02 0.1094 0.809 1702776 ChemDiv1_007764 CC1CC(C)CN(C1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A21 compound treatment 619604.0 28300.0 0.13 619286.0 -605.0 0.0 0.0873 0.6902 1973976 ChemDiv1_007765 CCN(CC)C(=O)Cn1cnc2sc(C(=O)N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c(C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A22 compound treatment 602592.0 11200.0 0.05 620748.0 857.0 0.0 0.0386 0.764 1589509 ChemDiv1_007766 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A23 mock treatment 590604.0 -741.0 0.0 611088.0 -8800.0 -0.04 -0.0332 -0.7587 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 A24 mock treatment 491607.0 -99700.0 -0.45 508064.0 -112000.0 -0.55 -0.7074 -0.9943 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B01 compound treatment 602423.0 11100.0 0.05 564901.0 -55000.0 -0.27 -0.1576 -0.569 1218261 ChemDiv1_007767 CCOc1ccc(NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B02 compound treatment 640325.0 49000.0 0.22 601068.0 -18800.0 -0.09 0.0891 0.374 1584145 ChemDiv1_007768 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C5CC=CCC5C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B03 compound treatment 700875.0 110000.0 0.49 674522.0 54600.0 0.27 0.5381 0.9608 1712141 ChemDiv1_007769 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B04 compound treatment 715815.0 124000.0 0.56 697046.0 77200.0 0.38 0.6642 0.9831 1864947 ChemDiv1_007770 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/3\C(=O)Nc4ccccc34)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B05 compound treatment 708507.0 117000.0 0.52 694428.0 74500.0 0.37 0.6319 0.9852 1482540 ChemDiv1_007771 CN(Cc1ccccc1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B06 compound treatment 710563.0 119000.0 0.53 686639.0 66700.0 0.33 0.6112 0.9735 1727301 ChemDiv1_007772 O=C(CC1SC(=O)N(CN2CCOCC2)C1=O)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B07 compound treatment 743948.0 153000.0 0.68 727840.0 108000.0 0.53 0.8612 0.9927 1463494 ChemDiv1_007773 CCOC(=O)C1CCCCN1C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B08 compound treatment 753700.0 162000.0 0.73 712532.0 92600.0 0.46 0.8384 0.9754 1973977 ChemDiv1_007774 Brc1cnc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B09 compound treatment 764496.0 173000.0 0.78 755736.0 136000.0 0.67 1.0239 0.9975 1203166 ChemDiv1_007775 CCCNC(=O)Cn1cnc2sc(C(=O)O)c(C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B10 compound treatment 739879.0 149000.0 0.66 705410.0 85500.0 0.42 0.7697 0.9763 1973978 ChemDiv1_007776 CCC1C(=O)NC(=NC1=O)SCc2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B11 compound treatment 757637.0 166000.0 0.74 731016.0 111000.0 0.55 0.9156 0.989 1973979 ChemDiv1_007777 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCCCC4C)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B12 compound treatment 727626.0 136000.0 0.61 685951.0 66100.0 0.33 0.6628 0.9574 1973980 ChemDiv1_007778 CCN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(Cl)cc4)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B13 compound treatment 760640.0 169000.0 0.76 739460.0 120000.0 0.59 0.9547 0.9926 1973981 ChemDiv1_007779 CC1CCCCN1c2ncnc3sc(C(=O)NCC4COc5ccccc5O4)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B14 compound treatment 716826.0 125000.0 0.56 698652.0 78800.0 0.39 0.6731 0.9841 1222385 ChemDiv1_007780 CCC(=O)N1N=C(CC1c2ccc(cc2)N(C)C)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B15 compound treatment 782953.0 192000.0 0.86 766489.0 147000.0 0.73 1.12 0.9966 1973982 ChemDiv1_007781 CCn1c(C(=O)O)c(CC(=O)Nc2cc(Cl)c(OC)cc2OC)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B16 compound treatment 740578.0 149000.0 0.67 682365.0 62500.0 0.31 0.6912 0.9388 1668199 ChemDiv1_007782 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B17 compound treatment 739720.0 148000.0 0.66 761413.0 142000.0 0.7 0.9654 0.9996 1973983 ChemDiv1_007783 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccc(F)cc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B18 compound treatment 716942.0 126000.0 0.56 749268.0 129000.0 0.64 0.8507 0.9979 1611007 ChemDiv1_007784 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B19 compound treatment 735374.0 144000.0 0.64 737978.0 118000.0 0.58 0.8695 0.9988 1973984 ChemDiv1_007785 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3cccc(Cl)c3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B20 compound treatment 809391.0 218000.0 0.98 792829.0 173000.0 0.86 1.296 0.9979 1612101 ChemDiv1_007786 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B21 compound treatment 705689.0 114000.0 0.51 714071.0 94200.0 0.47 0.6918 0.9989 1787042 ChemDiv1_007787 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCNCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B22 compound treatment 674466.0 83100.0 0.37 694603.0 74700.0 0.37 0.5248 1.0 1973985 ChemDiv1_007788 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B23 mock treatment 648229.0 56900.0 0.25 679999.0 60100.0 0.3 0.3906 0.997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 B24 mock treatment 519657.0 -71700.0 -0.32 553398.0 -66500.0 -0.33 -0.4598 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C01 compound treatment 613325.0 22000.0 0.1 569166.0 -50700.0 -0.25 -0.1081 -0.4006 1147452 ChemDiv1_007789 CCOC(=O)c1sc2nc(C)nc(N3CCc4ccccc4C3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C02 compound treatment 657792.0 66400.0 0.3 625140.0 5250.0 0.03 0.2287 0.766 1973986 ChemDiv1_007790 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(cc4)[N+](=O)[O-])c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C03 compound treatment 713627.0 122000.0 0.55 689191.0 69300.0 0.34 0.6298 0.9747 1473475 ChemDiv1_007791 Cc1cccc(c1)c2nc(NCc3ccc4OCOc4c3)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C04 compound treatment 692096.0 101000.0 0.45 663396.0 43500.0 0.22 0.4713 0.9429 1224788 ChemDiv1_007792 CC1CN(CCN1c2ccc(C)cc2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C05 compound treatment 703455.0 112000.0 0.5 681579.0 61700.0 0.31 0.5709 0.9717 1430556 ChemDiv1_007793 COc1ccc(CCNc2nc(C)nc3sc4CCCCc4c23)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C06 compound treatment 733189.0 142000.0 0.63 675411.0 55500.0 0.28 0.6435 0.9299 1442537 ChemDiv1_007794 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(Cc5ccccc5)CC4)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C07 compound treatment 756204.0 165000.0 0.74 730540.0 111000.0 0.55 0.9094 0.9893 1973987 ChemDiv1_007795 Cc1ccc(cc1)c2nc(N3CCC(CC3)(N4CCCCC4)C(=O)N)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C08 compound treatment 771749.0 180000.0 0.81 733512.0 114000.0 0.56 0.969 0.9844 1973988 ChemDiv1_007796 CCOC(=O)CNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C09 compound treatment 766306.0 175000.0 0.78 722823.0 103000.0 0.51 0.9144 0.9784 1719553 ChemDiv1_007797 COC(=O)Cc1nc(N2CCN(Cc3ccccc3)CC2)c4c(C)c(C)sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C10 compound treatment 743151.0 152000.0 0.68 713691.0 93800.0 0.46 0.8091 0.9828 1412683 ChemDiv1_007798 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCCN5CCOCC5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C11 compound treatment 804880.0 214000.0 0.96 749868.0 130000.0 0.64 1.1312 0.9815 1211676 ChemDiv1_007799 CCOC(=O)c1sc2nc(CC(=O)OC)nc(Nc3ccccc3OCC)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C12 compound treatment 756181.0 165000.0 0.74 749565.0 130000.0 0.64 0.976 0.9976 1696399 ChemDiv1_007800 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C13 compound treatment 763855.0 173000.0 0.77 753646.0 134000.0 0.66 1.0146 0.9971 1230747 ChemDiv1_007801 CCOC(=O)c1sc2ncn(CC(=O)N(CC)CC)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C14 compound treatment 734999.0 144000.0 0.64 753858.0 134000.0 0.66 0.924 0.9999 1376308 ChemDiv1_007802 CCN(CC)C(=O)Cn1cnc2sc(C(=O)N3CCN(Cc4ccc5OCOc5c4)CC3)c(C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C15 compound treatment 790129.0 199000.0 0.89 767996.0 148000.0 0.73 1.148 0.9954 1720238 ChemDiv1_007803 CCCCN(CC)C(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C16 compound treatment 709346.0 118000.0 0.53 742276.0 122000.0 0.61 0.8022 0.9976 1647635 ChemDiv1_007804 CCOC(=O)N1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C17 compound treatment 762840.0 171000.0 0.77 754684.0 135000.0 0.67 1.015 0.9976 1361082 ChemDiv1_007805 CCCN1CCN(CC1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C18 compound treatment 744510.0 153000.0 0.69 713992.0 94100.0 0.47 0.8144 0.9823 1973989 ChemDiv1_007806 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C19 compound treatment 750801.0 159000.0 0.71 733858.0 114000.0 0.56 0.9039 0.9933 1973990 ChemDiv1_007807 CCOC(=O)c1nc(N2CCC(CC2)(N3CCCCC3)C(=O)N)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C20 compound treatment 706815.0 115000.0 0.52 700855.0 81000.0 0.4 0.6491 0.9921 1537236 ChemDiv1_007808 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccc(F)cc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C21 compound treatment 740124.0 149000.0 0.67 736885.0 117000.0 0.58 0.8807 0.9976 1973991 ChemDiv1_007809 Cc1c(sc2ncn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C22 compound treatment 682815.0 91500.0 0.41 685989.0 66100.0 0.33 0.5211 0.9939 1973992 ChemDiv1_007810 Fc1ccccc1c2nc(NCc3cccs3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C23 mock treatment 733261.0 142000.0 0.64 702191.0 82300.0 0.41 0.7375 0.977 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 C24 mock treatment 519771.0 -71600.0 -0.32 547942.0 -71900.0 -0.36 -0.4786 -0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D01 compound treatment 613618.0 22300.0 0.1 556616.0 -63300.0 -0.31 -0.1511 -0.4595 1400070 ChemDiv1_007811 COc1ccc(OC)c(NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D02 compound treatment 617072.0 25700.0 0.12 626773.0 6880.0 0.03 0.1055 0.8787 1554058 ChemDiv1_007812 CC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D03 compound treatment 691189.0 99800.0 0.45 659023.0 39100.0 0.19 0.4531 0.9301 1973993 ChemDiv1_007813 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)Nc5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D04 compound treatment 683264.0 91900.0 0.41 688280.0 68400.0 0.34 0.5305 0.9953 1973994 ChemDiv1_007814 COc1cc(ccc1O)C(=O)NN2C(=O)/C(=C/3\C(=O)Nc4cc(Br)ccc34)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D05 compound treatment 714653.0 123000.0 0.55 694908.0 75000.0 0.37 0.6531 0.9815 1735640 ChemDiv1_007815 CN(CCc1ccccn1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D06 compound treatment 697949.0 107000.0 0.48 679564.0 59700.0 0.3 0.5465 0.9735 1973995 ChemDiv1_007816 Brc1ccc(NC(=O)CCSc2nc3ccccc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D07 compound treatment 751942.0 161000.0 0.72 737216.0 117000.0 0.58 0.9193 0.9944 1973996 ChemDiv1_007817 Cc1cc(NC(=O)c2nn(c3ccc(Cl)cc3)c(=O)c4ccccc24)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D08 compound treatment 743821.0 152000.0 0.68 710082.0 90200.0 0.45 0.7986 0.9789 1973997 ChemDiv1_007818 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3ccccc3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D09 compound treatment 784743.0 193000.0 0.87 737814.0 118000.0 0.58 1.0252 0.9817 1548782 ChemDiv1_007819 CC(C)c1ccc(NC(=O)Cn2cnc3sc(C(=O)O)c(C)c3c2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D10 compound treatment 749885.0 159000.0 0.71 719159.0 99300.0 0.49 0.8495 0.9839 1730627 ChemDiv1_007820 Clc1c(sc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D11 compound treatment 782261.0 191000.0 0.85 756067.0 136000.0 0.67 1.0813 0.9931 1973998 ChemDiv1_007821 CCOC(=O)N1CCN(CC1)C(=O)CNC(=O)Cn2cnc3sc4CCCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D12 compound treatment 740055.0 149000.0 0.67 694213.0 74300.0 0.37 0.7311 0.961 1973999 ChemDiv1_007822 COc1ccc(Oc2c(oc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D13 compound treatment 763873.0 173000.0 0.77 770344.0 150000.0 0.75 1.0731 0.9998 1974000 ChemDiv1_007823 CCN(CCCNC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C)Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D14 compound treatment 697375.0 106000.0 0.47 746630.0 127000.0 0.63 0.7796 0.9905 1974001 ChemDiv1_007824 CN(C)c1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D15 compound treatment 799160.0 208000.0 0.93 784481.0 165000.0 0.82 1.2343 0.9978 1974002 ChemDiv1_007825 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(Br)cc2C)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D16 compound treatment 750959.0 160000.0 0.71 699594.0 79700.0 0.39 0.7844 0.9609 1217947 ChemDiv1_007826 COc1ccc(cc1OC)C2CC(=NN2C(=O)C)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D17 compound treatment 778455.0 187000.0 0.84 789663.0 170000.0 0.84 1.1869 1.0 1974003 ChemDiv1_007827 CCn1c(C(=O)O)c(CC(=O)N(C)c2ccc(Br)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D18 compound treatment 721596.0 130000.0 0.58 723881.0 104000.0 0.52 0.7765 0.9981 1598143 ChemDiv1_007828 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D19 compound treatment 719787.0 128000.0 0.57 723691.0 104000.0 0.51 0.7702 0.9984 1974004 ChemDiv1_007829 CCN(CC)CCNC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D20 compound treatment 749991.0 159000.0 0.71 770609.0 151000.0 0.75 1.0301 0.9997 1403804 ChemDiv1_007830 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D21 compound treatment 730917.0 140000.0 0.62 753905.0 134000.0 0.66 0.9112 0.9995 1974005 ChemDiv1_007831 CC(C)(C)OC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D22 compound treatment 682236.0 90900.0 0.41 726727.0 107000.0 0.53 0.6619 0.9916 1190373 ChemDiv1_007832 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4cccc(C)c4nc3Cl)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D23 mock treatment 674532.0 83200.0 0.37 712200.0 92300.0 0.46 0.5867 0.9948 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 D24 mock treatment 533345.0 -58000.0 -0.26 539558.0 -80300.0 -0.4 -0.465 -0.9786 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E01 compound treatment 635756.0 44400.0 0.2 596276.0 -23600.0 -0.12 0.0579 0.2508 1712359 ChemDiv1_007833 COc1ccc(cc1OC)c2nc(NCc3ccc(F)cc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E02 compound treatment 676770.0 85400.0 0.38 612500.0 -7390.0 -0.04 0.2445 0.6365 1729639 ChemDiv1_007834 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCC(C)CC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E03 compound treatment 718469.0 127000.0 0.57 692807.0 72900.0 0.36 0.6578 0.9759 1974006 ChemDiv1_007835 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)c3ncnc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E04 compound treatment 698485.0 107000.0 0.48 694823.0 74900.0 0.37 0.6016 0.992 1293523 ChemDiv1_007836 Cc1c(sc2nc(C)nc(N3CCCCC3)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E05 compound treatment 741357.0 150000.0 0.67 721111.0 101000.0 0.5 0.8294 0.9896 1247213 ChemDiv1_007837 CCOC(=O)c1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E06 compound treatment 754996.0 164000.0 0.73 725601.0 106000.0 0.52 0.8883 0.9865 1974007 ChemDiv1_007838 CC(C)c1ccc(NC(=O)c2sc3ncn(CC(=O)Nc4cccc(c4)C(F)(F)F)c(=O)c3c2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E07 compound treatment 691299.0 100000.0 0.45 705822.0 85900.0 0.43 0.6174 0.9997 1380258 ChemDiv1_007839 CCOC(CNc1nc(nc2ccccc12)c3ccc(C)cc3)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E08 compound treatment 838856.0 248000.0 1.11 736597.0 117000.0 0.58 1.1922 0.954 1680197 ChemDiv1_007840 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)Nc5ccc6OCOc6c5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E09 compound treatment 761540.0 170000.0 0.76 704776.0 84900.0 0.42 0.8361 0.9608 1513233 ChemDiv1_007841 COC(=O)Cc1nc(N2CCN(Cc3ccc4OCOc4c3)CC2)c5c(C)c(C)sc5n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E10 compound treatment 759299.0 168000.0 0.75 692842.0 73000.0 0.36 0.7872 0.9436 1675995 ChemDiv1_007842 CCOC(=O)C1CCCN(C1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E11 compound treatment 802717.0 211000.0 0.95 779260.0 159000.0 0.79 1.2273 0.9959 1660744 ChemDiv1_007843 CCOC(=O)CNc1nc(CC(=O)OC)nc2sc(C(=O)OCC)c(C)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E12 compound treatment 799882.0 209000.0 0.93 712500.0 92600.0 0.46 0.9845 0.9465 1121035 ChemDiv1_007844 COc1cc(Cl)c(C)cc1NC(=O)c2sc3ncn(CC(=O)Nc4ccc(C)c(Cl)c4)c(=O)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E13 compound treatment 761973.0 171000.0 0.76 760328.0 140000.0 0.7 1.032 0.9989 1480042 ChemDiv1_007845 CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E14 compound treatment 725508.0 134000.0 0.6 760357.0 140000.0 0.7 0.9167 0.9973 1539940 ChemDiv1_007846 CCN(CC)c1nc(C)nc2sc(C(=O)O)c(C)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E15 compound treatment 806010.0 215000.0 0.96 766404.0 147000.0 0.73 1.1927 0.9904 1604567 ChemDiv1_007847 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E16 compound treatment 782135.0 191000.0 0.85 757415.0 138000.0 0.68 1.0856 0.9937 1117891 ChemDiv1_007848 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E17 compound treatment 776276.0 185000.0 0.83 794423.0 175000.0 0.86 1.1967 0.9998 1974008 ChemDiv1_007849 CCOC(CNC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E18 compound treatment 758403.0 167000.0 0.75 751592.0 132000.0 0.65 0.9901 0.9977 1974009 ChemDiv1_007850 COc1ccccc1N2CCN(CC2)C(=O)c3sc4ncnc(N5CCN(CC5)c6ccccn6)c4c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E19 compound treatment 779670.0 188000.0 0.84 760250.0 140000.0 0.7 1.0878 0.9954 1974010 ChemDiv1_007851 CCOC(=O)c1nc(N2CCC3(CC2)OCCO3)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E20 compound treatment 751351.0 160000.0 0.72 733707.0 114000.0 0.56 0.9051 0.993 1659096 ChemDiv1_007852 COc1ccc(C)cc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E21 compound treatment 753340.0 162000.0 0.73 769485.0 150000.0 0.74 1.0368 0.9999 1263937 ChemDiv1_007853 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)NCc4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E22 compound treatment 731487.0 140000.0 0.63 732611.0 113000.0 0.56 0.8384 0.9983 1390036 ChemDiv1_007854 CCN1CCN(CC1)c2ncnc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E23 mock treatment 720287.0 129000.0 0.58 712079.0 92200.0 0.46 0.7311 0.9933 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 E24 mock treatment 498506.0 -92800.0 -0.42 537636.0 -82300.0 -0.41 -0.582 -1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F01 compound treatment 601946.0 10600.0 0.05 552548.0 -67300.0 -0.33 -0.2023 -0.6005 1974011 ChemDiv1_007855 COc1ccc(cc1NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F02 compound treatment 651090.0 59700.0 0.27 582151.0 -37700.0 -0.19 0.0569 0.1744 1787043 ChemDiv1_007856 OC(=O)C1CC=CCC1C(=O)N2CCN(CC2)c3nc(c4ccccc4)c5cc(ccc5n3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F03 compound treatment 656950.0 65600.0 0.29 670510.0 50600.0 0.25 0.385 0.9969 1428168 ChemDiv1_007857 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)NCc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F04 compound treatment 690527.0 99200.0 0.44 657161.0 37300.0 0.18 0.4445 0.9244 1781461 ChemDiv1_007858 Cc1c(N2C(=O)S/C(=C\3/C(=O)Nc4ccccc34)/C2=O)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F05 compound treatment 709539.0 118000.0 0.53 682597.0 62700.0 0.31 0.5938 0.9678 1547203 ChemDiv1_007859 CC1CCCCN1c2ncnc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F06 compound treatment 710459.0 119000.0 0.53 705657.0 85800.0 0.42 0.6775 0.9937 1974012 ChemDiv1_007860 Brc1ccccc1NC(=O)CCSc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F07 compound treatment 753817.0 162000.0 0.73 730197.0 110000.0 0.55 0.9007 0.9901 1974013 ChemDiv1_007861 CN(C1CCCCC1)C(=O)c2nn(c3ccc(Cl)cc3)c(=O)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F08 compound treatment 736564.0 145000.0 0.65 725181.0 105000.0 0.52 0.8285 0.994 1974014 ChemDiv1_007862 Brc1ccc(cc1)c2csc(NC(=O)CSC3=NC(=O)C(Cc4ccccc4)C(=O)N3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F09 compound treatment 745280.0 154000.0 0.69 740362.0 120000.0 0.6 0.9092 0.9974 1974015 ChemDiv1_007863 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCN(CC4)c5cccc(Cl)c5)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F10 compound treatment 739046.0 148000.0 0.66 730923.0 111000.0 0.55 0.8564 0.9958 1383669 ChemDiv1_007864 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCCCC4)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F11 compound treatment 767251.0 176000.0 0.79 743311.0 123000.0 0.61 0.9891 0.9922 1974016 ChemDiv1_007865 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(Cc5ccccc5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F12 compound treatment 757867.0 167000.0 0.75 723653.0 104000.0 0.51 0.8906 0.9835 1146438 ChemDiv1_007866 Cc1cccc(Oc2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F13 compound treatment 768473.0 177000.0 0.79 746076.0 126000.0 0.63 1.0027 0.9931 1974017 ChemDiv1_007867 CCCN1CCN(CC1)c2ncnc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F14 compound treatment 733344.0 142000.0 0.64 738995.0 119000.0 0.59 0.8667 0.9993 1723164 ChemDiv1_007868 CC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F15 compound treatment 734181.0 143000.0 0.64 755138.0 135000.0 0.67 0.9259 0.9997 1606258 ChemDiv1_007869 CCOC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F16 compound treatment 764618.0 173000.0 0.78 759818.0 140000.0 0.69 1.0386 0.9984 1705842 ChemDiv1_007870 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F17 compound treatment 779752.0 188000.0 0.84 796159.0 176000.0 0.87 1.2138 0.9998 1974018 ChemDiv1_007871 CCn1c(C(=O)O)c(CC(=O)N(C)c2cccc(c2)C(F)(F)F)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F18 compound treatment 773563.0 182000.0 0.82 771787.0 152000.0 0.75 1.1088 0.9992 1485639 ChemDiv1_007872 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F19 compound treatment 745885.0 155000.0 0.69 750785.0 131000.0 0.65 0.9477 0.9995 1974019 ChemDiv1_007873 CC1CCCN(C1)C(=O)c2sc3nc(C)nc(N4CCN(C)CC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F20 compound treatment 776957.0 186000.0 0.83 757225.0 137000.0 0.68 1.0686 0.9951 1308157 ChemDiv1_007874 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F21 compound treatment 898216.0 307000.0 1.37 930412.0 311000.0 1.54 2.059 0.9984 1787046 ChemDiv1_007875 OC(=O)C1CCCN1c2nc(c3ccccc3)c4cc(ccc4n2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F22 compound treatment 682472.0 91100.0 0.41 735351.0 115000.0 0.57 0.6929 0.9863 1704053 ChemDiv1_007876 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccc(C)cc4nc3Cl)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F23 mock treatment 681065.0 89700.0 0.4 697253.0 77400.0 0.38 0.555 0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 F24 mock treatment 481222.0 -110000.0 -0.49 531345.0 -88500.0 -0.44 -0.6587 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G01 compound treatment 641501.0 50200.0 0.22 575852.0 -44000.0 -0.22 0.0045 0.0144 1215849 ChemDiv1_007877 COc1ccc(cc1OC)c2nc(NCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G02 compound treatment 668415.0 77100.0 0.34 617890.0 -2000.0 -0.01 0.2369 0.6865 1205912 ChemDiv1_007878 CCC(C)NC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G03 compound treatment 727554.0 136000.0 0.61 675765.0 55900.0 0.28 0.6269 0.9362 1621556 ChemDiv1_007879 Cc1sc2nc(C)nc(NC3CCN(Cc4ccccc4)CC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G04 compound treatment 720605.0 129000.0 0.58 675585.0 55700.0 0.28 0.6042 0.9426 1253066 ChemDiv1_007880 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC(C)CC5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G05 compound treatment 721958.0 131000.0 0.58 721434.0 102000.0 0.5 0.7691 0.9972 1691123 ChemDiv1_007881 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G06 compound treatment 721753.0 130000.0 0.58 709289.0 89400.0 0.44 0.7259 0.9907 1613944 ChemDiv1_007882 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G07 compound treatment 729833.0 138000.0 0.62 730712.0 111000.0 0.55 0.8265 0.9982 1418585 ChemDiv1_007883 CCOC(=O)N1CCN(CC1)c2nc(nc3ccccc23)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G08 compound treatment 760447.0 169000.0 0.76 721305.0 101000.0 0.5 0.8905 0.9802 1450370 ChemDiv1_007884 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC6(CC5)OCCO6)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G09 compound treatment 763022.0 172000.0 0.77 782643.0 163000.0 0.81 1.1135 0.9997 1592211 ChemDiv1_007885 CC1CCCN(C1)C(=O)Cn2cnc3sc(C(=O)Nc4c(C)cc(Br)cc4C)c(C)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G10 compound treatment 771465.0 180000.0 0.81 718335.0 98400.0 0.49 0.915 0.971 1277241 ChemDiv1_007886 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G11 compound treatment 745390.0 154000.0 0.69 726284.0 106000.0 0.53 0.8603 0.9912 1241523 ChemDiv1_007887 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CC(C)CC(C)C3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G12 compound treatment 800513.0 209000.0 0.94 776745.0 157000.0 0.78 1.2115 0.9957 1974020 ChemDiv1_007888 COc1ccc(cc1NC(=O)c2sc3ncnc(N4CCCCC4)c3c2C)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G13 compound treatment 770468.0 179000.0 0.8 770301.0 150000.0 0.75 1.0938 0.9993 1430401 ChemDiv1_007889 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccccc5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G14 compound treatment 801171.0 210000.0 0.94 803867.0 184000.0 0.91 1.3086 0.9999 1321254 ChemDiv1_007890 Cc1c(sc2ncnc(N3CCCCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G15 compound treatment 809459.0 218000.0 0.98 800526.0 181000.0 0.89 1.3231 0.9991 1459968 ChemDiv1_007891 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G16 compound treatment 780800.0 189000.0 0.85 765704.0 146000.0 0.72 1.1104 0.9968 1339394 ChemDiv1_007892 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G17 compound treatment 795673.0 204000.0 0.91 776258.0 156000.0 0.77 1.1945 0.9966 1557599 ChemDiv1_007893 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G18 compound treatment 742230.0 151000.0 0.68 765388.0 145000.0 0.72 0.9873 0.9995 1640539 ChemDiv1_007894 CN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G19 compound treatment 788314.0 197000.0 0.88 795838.0 176000.0 0.87 1.2398 1.0 1431695 ChemDiv1_007895 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)NCC4COc5ccccc5O4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G20 compound treatment 750878.0 160000.0 0.71 704642.0 84800.0 0.42 0.8018 0.9679 1137909 ChemDiv1_007896 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G21 compound treatment 659284.0 67900.0 0.3 676779.0 56900.0 0.28 0.4143 0.9993 1411056 ChemDiv1_007897 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G22 compound treatment 721348.0 130000.0 0.58 730773.0 111000.0 0.55 0.7999 0.9996 1428083 ChemDiv1_007898 CC1CCCCN1C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G23 mock treatment 698303.0 107000.0 0.48 736603.0 117000.0 0.58 0.7474 0.9956 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 G24 mock treatment 520217.0 -71100.0 -0.32 536318.0 -83600.0 -0.41 -0.5179 -0.9916 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H01 compound treatment 591052.0 -293.0 0.0 554836.0 -65100.0 -0.32 -0.2288 -0.71 1339200 ChemDiv1_007899 CCOc1ccccc1NC(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H02 compound treatment 629706.0 38400.0 0.17 598548.0 -21300.0 -0.11 0.0467 0.2314 1974021 ChemDiv1_007900 [O-][N+](=O)c1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H03 compound treatment 680844.0 89500.0 0.4 644741.0 24900.0 0.12 0.3703 0.8836 1974022 ChemDiv1_007901 COc1ccc(cc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H04 compound treatment 689500.0 98200.0 0.44 657430.0 37500.0 0.19 0.4422 0.9268 1974023 ChemDiv1_007902 CCOc1ccc(/N=C/2\NC(=O)\C(=C\3/C(=O)Nc4ccc(Br)cc34)\S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H05 compound treatment 703968.0 113000.0 0.5 690635.0 70700.0 0.35 0.6043 0.9842 1387828 ChemDiv1_007903 CCN(CC)CCNc1nc(nc2ccccc12)c3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H06 compound treatment 686693.0 95300.0 0.43 649520.0 29600.0 0.15 0.4056 0.8986 1392980 ChemDiv1_007904 CCOc1ccc2nc(SCCC(=O)Nc3ccc(OC)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H07 compound treatment 730479.0 139000.0 0.62 708893.0 89000.0 0.44 0.7522 0.9857 1974024 ChemDiv1_007905 CCOC(=O)C1CCCN(C1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H08 compound treatment 695745.0 104000.0 0.47 706112.0 86200.0 0.43 0.6325 0.999 1974025 ChemDiv1_007906 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)N3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H09 compound treatment 717630.0 126000.0 0.57 735474.0 116000.0 0.57 0.8046 1.0 1974026 ChemDiv1_007907 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)N4CCC(Cc5ccccc5)CC4)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H10 compound treatment 737561.0 146000.0 0.65 689431.0 69500.0 0.34 0.7064 0.9551 1579724 ChemDiv1_007908 Cc1ccc(NC(=O)CC2SC(=O)N(CN3CCOCC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H11 compound treatment 766976.0 176000.0 0.79 721094.0 101000.0 0.5 0.9104 0.9764 1974027 ChemDiv1_007909 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(CC4)c5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H12 compound treatment 720642.0 129000.0 0.58 713089.0 93200.0 0.46 0.7357 0.9937 1468348 ChemDiv1_007910 C=CCn1c(SCC(=O)NCCN2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H13 compound treatment 766313.0 175000.0 0.78 736975.0 117000.0 0.58 0.964 0.9891 1974028 ChemDiv1_007911 Fc1ccc(cc1)N2CCN(CC2)C(=O)CNC(=O)Cn3cnc4sc5CCCCc5c4c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H14 compound treatment 708736.0 117000.0 0.53 746024.0 126000.0 0.62 0.8134 0.9963 1974029 ChemDiv1_007912 OC(=O)CCC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H15 compound treatment 776832.0 185000.0 0.83 756186.0 136000.0 0.68 1.0645 0.9947 1974030 ChemDiv1_007913 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccccc3F)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H16 compound treatment 750463.0 159000.0 0.71 757493.0 138000.0 0.68 0.9857 0.9998 1258712 ChemDiv1_007914 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H17 compound treatment 761798.0 170000.0 0.76 763226.0 143000.0 0.71 1.0416 0.9994 1974031 ChemDiv1_007915 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cc(OC)ccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H18 compound treatment 762726.0 171000.0 0.77 778751.0 159000.0 0.79 1.0989 0.9999 1227360 ChemDiv1_007916 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H19 compound treatment 748222.0 157000.0 0.7 764612.0 145000.0 0.72 1.0035 0.9999 1974032 ChemDiv1_007917 COc1ccc(Cl)cc1N(C)C(=O)CCNC(=O)Cn2cnc3ccccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H20 compound treatment 712390.0 121000.0 0.54 755067.0 135000.0 0.67 0.8566 0.9945 1974033 ChemDiv1_007918 COc1ccc(cc1OC)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H21 compound treatment 734763.0 143000.0 0.64 711166.0 91300.0 0.45 0.7737 0.9853 1153036 ChemDiv1_007919 OC(=O)CC1(CC(=O)N2CCN(CC2)c3nc(c4ccccc4)c5ccccc5n3)CCCC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H22 compound treatment 698636.0 107000.0 0.48 683395.0 63500.0 0.31 0.5621 0.979 1283533 ChemDiv1_007920 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4cc(C)ccc4nc3Cl)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H23 mock treatment 665873.0 74500.0 0.33 704637.0 84700.0 0.42 0.5328 0.9935 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 H24 mock treatment 504746.0 -86600.0 -0.39 524017.0 -95900.0 -0.47 -0.6099 -0.9949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I01 compound treatment 623186.0 31800.0 0.14 562880.0 -57000.0 -0.28 -0.0989 -0.3127 1282612 ChemDiv1_007921 COc1ccc(cc1OC)c2nc(NC3CCCCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I02 compound treatment 671074.0 79700.0 0.36 607896.0 -12000.0 -0.06 0.2103 0.5814 1656125 ChemDiv1_007922 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I03 compound treatment 689628.0 98300.0 0.44 655731.0 35800.0 0.18 0.4366 0.9203 1165995 ChemDiv1_007923 COc1ccc(CCNc2nc(C)nc3sc(C)c(C)c23)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I04 compound treatment 699127.0 108000.0 0.48 670375.0 50500.0 0.25 0.518 0.9532 1974034 ChemDiv1_007924 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCCCN5CCOCC5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I05 compound treatment 717662.0 126000.0 0.57 686438.0 66500.0 0.33 0.6329 0.967 1639480 ChemDiv1_007925 CN(C)CCNc1nc(Cc2ccccc2)nc3sc4CCCCc4c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I06 compound treatment 724452.0 133000.0 0.6 679492.0 59600.0 0.3 0.6301 0.9475 1148725 ChemDiv1_007926 CCN1CCCC1CNC(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I07 compound treatment 745822.0 154000.0 0.69 728027.0 108000.0 0.54 0.8678 0.992 1342021 ChemDiv1_007927 Cc1ccc(cc1)c2nc(N3CCC(CC3)C(=O)N)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I08 compound treatment 783647.0 192000.0 0.86 737566.0 118000.0 0.58 1.0209 0.982 1974035 ChemDiv1_007928 CCOC(CNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I09 compound treatment 783526.0 192000.0 0.86 735122.0 115000.0 0.57 1.0119 0.9802 1231281 ChemDiv1_007929 CCOC(=O)c1nc(Nc2cccc(NC(=O)C)c2)c3ccccc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I10 compound treatment 770461.0 179000.0 0.8 718244.0 98400.0 0.49 0.9115 0.9715 1974036 ChemDiv1_007930 CCN(CC)CCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I11 compound treatment 770246.0 179000.0 0.8 754748.0 135000.0 0.67 1.0387 0.9959 1245088 ChemDiv1_007931 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(F)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I12 compound treatment 713011.0 122000.0 0.54 644604.0 24700.0 0.12 0.4717 0.845 1430619 ChemDiv1_007932 CCN(C(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I13 compound treatment 766184.0 175000.0 0.78 756584.0 137000.0 0.68 1.0322 0.9974 1376432 ChemDiv1_007933 CC1CC(C)CN(C1)C(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I14 compound treatment 752911.0 162000.0 0.72 718356.0 98500.0 0.49 0.8563 0.9816 1636390 ChemDiv1_007934 Cc1c(sc2ncn(CC(=O)N3CCOCC3)c(=O)c12)C(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I15 compound treatment 795418.0 204000.0 0.91 768914.0 149000.0 0.74 1.168 0.9944 1706317 ChemDiv1_007935 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I16 compound treatment 754300.0 163000.0 0.73 722206.0 102000.0 0.51 0.8742 0.9842 1607845 ChemDiv1_007936 CN(Cc1ccccc1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I17 compound treatment 774811.0 183000.0 0.82 787471.0 168000.0 0.83 1.1677 1.0 1641962 ChemDiv1_007937 CCOC(CNc1nc(nc2sc3CCCCc3c12)C(=O)OCC)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I18 compound treatment 729900.0 139000.0 0.62 729866.0 110000.0 0.54 0.8238 0.9979 1714854 ChemDiv1_007938 COc1ccc(OC)c(NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I19 compound treatment 724909.0 134000.0 0.6 715167.0 95300.0 0.47 0.7565 0.9931 1158840 ChemDiv1_007939 CCOC(=O)C1CCCN(C1)c2nc(nc3sc4CCCCc4c23)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I20 compound treatment 730236.0 139000.0 0.62 748843.0 129000.0 0.64 0.8913 0.9999 1349272 ChemDiv1_007940 CCCN(CCC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I21 compound treatment 750942.0 160000.0 0.71 768950.0 149000.0 0.74 1.0273 0.9999 1399150 ChemDiv1_007941 CCN(CC)C(=O)Cn1cnc2sc(C(=O)Nc3c(F)cc(F)cc3Br)c(C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I22 compound treatment 709978.0 119000.0 0.53 736322.0 116000.0 0.58 0.7834 0.9991 1136979 ChemDiv1_007942 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccccc6)CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I23 mock treatment 703671.0 112000.0 0.5 721742.0 102000.0 0.5 0.7123 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 I24 mock treatment 522341.0 -69000.0 -0.31 545926.0 -74000.0 -0.37 -0.4775 -0.9964 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J01 compound treatment 602103.0 10800.0 0.05 545933.0 -74000.0 -0.37 -0.225 -0.6089 1636890 ChemDiv1_007943 CN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J02 compound treatment 633074.0 41700.0 0.19 601750.0 -18100.0 -0.09 0.0685 0.3306 1520547 ChemDiv1_007944 CC(=O)N1CCN(CC1)c2nc(c3ccccc3Cl)c4cc(Br)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J03 compound treatment 688363.0 97000.0 0.43 654939.0 35000.0 0.17 0.4299 0.9191 1974037 ChemDiv1_007945 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccc7OCOc7c6)CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J04 compound treatment 690077.0 98700.0 0.44 636994.0 17100.0 0.08 0.3724 0.8276 1941792 ChemDiv1_007946 COc1ccc(cc1)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J05 compound treatment 701691.0 110000.0 0.49 684491.0 64600.0 0.32 0.5756 0.9779 1145694 ChemDiv1_007947 Fc1ccccc1c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J06 compound treatment 689801.0 98500.0 0.44 674433.0 54500.0 0.27 0.5027 0.9724 1260944 ChemDiv1_007948 CC(=O)Nc1cccc(NC(=O)CSc2nc3ccccc3o2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J07 compound treatment 722856.0 132000.0 0.59 704565.0 84700.0 0.42 0.7129 0.9862 1974038 ChemDiv1_007949 CCN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J08 compound treatment 706795.0 115000.0 0.52 710485.0 90600.0 0.45 0.6828 0.9975 1484828 ChemDiv1_007950 Cc1cc(NC(=O)CSc2ncn[nH]2)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J09 compound treatment 733350.0 142000.0 0.64 722677.0 103000.0 0.51 0.8095 0.994 1974039 ChemDiv1_007951 CC1CCCCN1c2ncnc3sc(C(=O)N4CCC(CC4)(N5CCCCC5)C(=O)N)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J10 compound treatment 743822.0 152000.0 0.68 684918.0 65000.0 0.32 0.7104 0.9413 1974040 ChemDiv1_007952 CCCCOC(=O)Nc1nc(C)c(s1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J11 compound treatment 754506.0 163000.0 0.73 732616.0 113000.0 0.56 0.9113 0.9912 1974041 ChemDiv1_007953 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCC(=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J12 compound treatment 741426.0 150000.0 0.67 723247.0 103000.0 0.51 0.8371 0.991 1466714 ChemDiv1_007954 Cc1sc2nc(SCC(=O)NCCN3CCOCC3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J13 compound treatment 749204.0 158000.0 0.71 736019.0 116000.0 0.58 0.9065 0.9948 1974042 ChemDiv1_007955 CCn1c(C(=O)O)c(CC(=O)Nc2nc3ccc(OC)cc3s2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J14 compound treatment 724158.0 133000.0 0.59 738848.0 119000.0 0.59 0.8371 1.0 1974043 ChemDiv1_007956 OC(=O)CCCC(=O)N1N=C(CC1c2ccccn2)c3c(c4ccccc4)c5cc(Cl)ccc5[nH]c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J15 compound treatment 754183.0 163000.0 0.73 746647.0 127000.0 0.63 0.9594 0.9972 1974044 ChemDiv1_007957 CCn1c(C(=O)O)c(CC(=O)NCCc2ccc(OC)c(OC)c2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J16 compound treatment 742241.0 151000.0 0.68 738504.0 119000.0 0.59 0.8931 0.9976 1621889 ChemDiv1_007958 COc1ccc(cc1)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J17 compound treatment 749251.0 158000.0 0.71 761852.0 142000.0 0.7 0.9971 1.0 1974045 ChemDiv1_007959 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J18 compound treatment 784055.0 193000.0 0.86 784916.0 165000.0 0.82 1.188 0.9996 1436300 ChemDiv1_007960 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J19 compound treatment 748402.0 157000.0 0.7 735766.0 116000.0 0.57 0.903 0.9949 1472083 ChemDiv1_007961 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J20 compound treatment 748379.0 157000.0 0.7 736637.0 117000.0 0.58 0.906 0.9953 1974046 ChemDiv1_007962 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J21 compound treatment 727500.0 136000.0 0.61 729816.0 110000.0 0.54 0.816 0.9984 1688559 ChemDiv1_007963 CC(C)(C)OC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J22 compound treatment 694423.0 103000.0 0.46 716643.0 96800.0 0.48 0.6652 0.9998 1659414 ChemDiv1_007964 COc1ccc(cc1OC)C2=NN(C(C2)c3cn(nc3c4ccccc4)c5ccccc5)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J23 mock treatment 692076.0 101000.0 0.45 674145.0 54300.0 0.27 0.5089 0.9694 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 J24 mock treatment 484426.0 -107000.0 -0.48 579288.0 -40600.0 -0.2 -0.4807 -0.9258 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K01 compound treatment 627600.0 36300.0 0.16 568036.0 -51900.0 -0.26 -0.0669 -0.2201 1730022 ChemDiv1_007965 COc1cc(cc(OC)c1OC)c2nc(NCc3ccc(F)cc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K02 compound treatment 643958.0 52600.0 0.24 613353.0 -6540.0 -0.03 0.1436 0.6042 1358960 ChemDiv1_007966 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(Cc5ccccc5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K03 compound treatment 721682.0 130000.0 0.58 656579.0 36700.0 0.18 0.5411 0.8854 1541557 ChemDiv1_007967 COc1ccccc1N2CCN(CC2)c3ncnc4sc5CCCCc5c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K04 compound treatment 683739.0 92400.0 0.41 658569.0 38700.0 0.19 0.4279 0.9388 1439265 ChemDiv1_007968 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5ccco5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K05 compound treatment 703948.0 113000.0 0.5 691189.0 71300.0 0.35 0.6062 0.9849 1657534 ChemDiv1_007969 C(Nc1nc(Cc2ccccc2)nc3sc4CCCCc4c13)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K06 compound treatment 686591.0 95200.0 0.43 681628.0 61700.0 0.31 0.5177 0.9867 1974047 ChemDiv1_007970 CCN(CC)CCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K07 compound treatment 717006.0 126000.0 0.56 710103.0 90200.0 0.45 0.7138 0.9935 1545022 ChemDiv1_007971 Cc1ccc(cc1)c2nc(N3CCC4(CC3)OCCO4)c5ccccc5n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K08 compound treatment 714685.0 123000.0 0.55 714558.0 94700.0 0.47 0.722 0.9967 1517188 ChemDiv1_007972 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5ccccn5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K09 compound treatment 738548.0 147000.0 0.66 721019.0 101000.0 0.5 0.8202 0.9909 1267848 ChemDiv1_007973 CCOC(=O)c1sc2ncnc(NCC3COc4ccccc4O3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K10 compound treatment 710867.0 120000.0 0.54 716718.0 96800.0 0.48 0.7175 0.9985 1272901 ChemDiv1_007974 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K11 compound treatment 746919.0 156000.0 0.7 720631.0 101000.0 0.5 0.8453 0.9866 1124849 ChemDiv1_007975 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K12 compound treatment 724523.0 133000.0 0.6 714193.0 94300.0 0.47 0.7519 0.9927 1658386 ChemDiv1_007976 CCCN(CCC)C(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K13 compound treatment 731870.0 141000.0 0.63 737679.0 118000.0 0.58 0.8574 0.9993 1591775 ChemDiv1_007977 COc1ccc(C)cc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K14 compound treatment 731083.0 140000.0 0.63 740027.0 120000.0 0.6 0.8631 0.9997 1739002 ChemDiv1_007978 Cc1sc2ncn(CC(=O)NCC(=O)N3CCN(CC3)c4ccc(F)cc4)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K15 compound treatment 772188.0 181000.0 0.81 778368.0 158000.0 0.79 1.1275 0.9999 1264092 ChemDiv1_007979 CCOc1ccccc1NC(=O)c2sc3nc(C)nc(N4CCOCC4)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K16 compound treatment 714605.0 123000.0 0.55 746670.0 127000.0 0.63 0.8342 0.9979 1688609 ChemDiv1_007980 CC1CCCCN1C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K17 compound treatment 763045.0 172000.0 0.77 762860.0 143000.0 0.71 1.0443 0.9992 1308514 ChemDiv1_007981 CCOC(=O)c1nc(N2CCN(CC2)c3ccccn3)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K18 compound treatment 685692.0 94300.0 0.42 695770.0 75900.0 0.38 0.5644 0.9983 1416045 ChemDiv1_007982 CCCCN(CC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K19 compound treatment 733707.0 142000.0 0.64 734053.0 114000.0 0.57 0.8505 0.9982 1719962 ChemDiv1_007983 CCOC(=O)c1nc(NCc2cccnc2)c3c4CCCCc4sc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K20 compound treatment 654330.0 63000.0 0.28 779783.0 160000.0 0.79 0.7594 0.9033 1482905 ChemDiv1_007984 CCOc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K21 compound treatment 726903.0 136000.0 0.61 762388.0 142000.0 0.71 0.9282 0.9972 1341822 ChemDiv1_007985 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K22 compound treatment 698950.0 108000.0 0.48 653059.0 33200.0 0.16 0.4568 0.8975 1435905 ChemDiv1_007986 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(Cc6ccccc6)CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K23 mock treatment 694413.0 103000.0 0.46 746439.0 127000.0 0.63 0.7695 0.9886 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 K24 mock treatment 522313.0 -69000.0 -0.31 548396.0 -71500.0 -0.35 -0.4689 -0.9977 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L01 compound treatment 603610.0 12300.0 0.05 540934.0 -79000.0 -0.39 -0.2378 -0.6019 1474666 ChemDiv1_007987 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCN(CC5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L02 compound treatment 633535.0 42200.0 0.19 589233.0 -30700.0 -0.15 0.0262 0.1079 1098309 ChemDiv1_007988 CC1(C)NC(Cc2c1[nH]c3ccccc23)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L03 compound treatment 684665.0 93300.0 0.42 656159.0 36300.0 0.18 0.4224 0.929 1198760 ChemDiv1_007989 CCN(CC)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L04 compound treatment 688825.0 97500.0 0.44 625972.0 6080.0 0.03 0.3299 0.7541 1941751 ChemDiv1_007990 COc1ccc(cc1OC)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L05 compound treatment 684967.0 93600.0 0.42 671929.0 52000.0 0.26 0.4786 0.9728 1190790 ChemDiv1_007991 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4)c12)C(=O)N5CCC(CC5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L06 compound treatment 687637.0 96300.0 0.43 623166.0 3280.0 0.02 0.3163 0.7332 1705476 ChemDiv1_007992 COc1ccc2[nH]c(SCC(=O)Nc3cccc(NC(=O)C)c3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L07 compound treatment 704580.0 113000.0 0.51 682201.0 62300.0 0.31 0.5767 0.9717 1974048 ChemDiv1_007993 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4F)c12)C(=O)N5CCC(CC5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L08 compound treatment 703619.0 112000.0 0.5 696122.0 76200.0 0.38 0.6224 0.9901 1974049 ChemDiv1_007994 Cc1cc(NC(=O)CSc2nnc(C)[nH]2)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L09 compound treatment 735099.0 144000.0 0.64 706732.0 86800.0 0.43 0.7592 0.9808 1974050 ChemDiv1_007995 COc1ccc(OC)c(NC(=O)c2sc3ncnc(N4CCCCC4C)c3c2C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L10 compound treatment 700920.0 110000.0 0.49 702907.0 83000.0 0.41 0.6376 0.9962 1974051 ChemDiv1_007996 CCCCOC(=O)Nc1nc2ccccc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L11 compound treatment 716659.0 125000.0 0.56 752382.0 132000.0 0.66 0.8608 0.9969 1974052 ChemDiv1_007997 CCN(CCCNC(=O)c1sc2ncn(CC(=O)N3CCCCC3C)c(=O)c2c1C)Cc4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L12 compound treatment 721143.0 130000.0 0.58 706401.0 86500.0 0.43 0.7139 0.9888 1929155 ChemDiv1_007998 CN1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L13 compound treatment 720756.0 129000.0 0.58 738560.0 119000.0 0.59 0.8253 1.0 1974053 ChemDiv1_007999 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(C)cc2Br)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L14 compound treatment 734641.0 143000.0 0.64 718511.0 98600.0 0.49 0.799 0.991 1974054 ChemDiv1_008000 CCOc1ccc2cc(C3=NN(C(C3)c4ccc(Br)cc4)C(=O)CCC(=O)O)c(Cl)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L15 compound treatment 762250.0 171000.0 0.77 756209.0 136000.0 0.68 1.0185 0.9981 1974055 ChemDiv1_008001 CCn1c(C(=O)O)c(CC(=O)N2CCN(Cc3ccccc3)CC2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L16 compound treatment 676832.0 85500.0 0.38 740157.0 120000.0 0.6 0.6919 0.9771 1686855 ChemDiv1_008002 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L17 compound treatment 747886.0 157000.0 0.7 707007.0 87100.0 0.43 0.8007 0.9729 1974056 ChemDiv1_008003 CCn1c(C(=O)O)c(CC(=O)N2CCN(CC2)c3ccc(OC)cc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L18 compound treatment 733473.0 142000.0 0.64 715931.0 96000.0 0.48 0.7863 0.9897 1225785 ChemDiv1_008004 COc1ccc(OC)c(c1)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L19 compound treatment 747040.0 156000.0 0.7 717529.0 97600.0 0.48 0.8348 0.9841 1256020 ChemDiv1_008005 CCOC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4cc(C)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L20 compound treatment 727034.0 136000.0 0.61 866016.0 246000.0 1.22 1.2916 0.9482 1974057 ChemDiv1_008006 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L21 compound treatment 718372.0 127000.0 0.57 713026.0 93100.0 0.46 0.7283 0.9946 1302214 ChemDiv1_008007 O=C(N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L22 compound treatment 672867.0 81500.0 0.36 684792.0 64900.0 0.32 0.4854 0.998 1385918 ChemDiv1_008008 COc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)C)c4cccs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L23 mock treatment 678397.0 87100.0 0.39 712384.0 92500.0 0.46 0.5995 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 L24 mock treatment 533124.0 -58200.0 -0.26 530127.0 -89800.0 -0.44 -0.4987 -0.9676 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M01 compound treatment 614287.0 22900.0 0.1 582583.0 -37300.0 -0.18 -0.0581 -0.2746 1334305 ChemDiv1_008009 CCOC(=O)C1CCN(CC1)c2nc(nc3ccccc23)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M02 compound treatment 612866.0 21500.0 0.1 591719.0 -28200.0 -0.14 -0.0306 -0.1802 1355735 ChemDiv1_008010 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCCC5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M03 compound treatment 680512.0 89200.0 0.4 642530.0 22600.0 0.11 0.3615 0.872 1707349 ChemDiv1_008011 COc1ccc(CCNc2ncnc3scc(c4ccccc4)c23)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M04 compound treatment 603153.0 11800.0 0.05 630608.0 10700.0 0.05 0.0749 1.0 1974058 ChemDiv1_008012 CCCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M05 compound treatment 672131.0 80800.0 0.36 668401.0 48500.0 0.24 0.4256 0.9803 1420071 ChemDiv1_008013 C(Nc1nc(Cc2ccccc2)nc3sc4CCCCc4c13)C5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M06 compound treatment 706951.0 116000.0 0.52 684495.0 64600.0 0.32 0.5922 0.9733 1974059 ChemDiv1_008014 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCC(CC5)(N6CCCCC6)C(=O)N)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M07 compound treatment 719776.0 128000.0 0.57 719696.0 99800.0 0.49 0.7561 0.9972 1186451 ChemDiv1_008015 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M08 compound treatment 731509.0 140000.0 0.63 695689.0 75800.0 0.38 0.7092 0.9699 1145236 ChemDiv1_008016 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)N5CCN(CC5)c6ccccn6)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M09 compound treatment 754000.0 163000.0 0.73 696453.0 76600.0 0.38 0.783 0.9538 1974060 ChemDiv1_008017 Cc1c(sc2ncnc(N3CCOCC3)c12)C(=O)N4CCN(CC4)c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M10 compound treatment 711785.0 120000.0 0.54 712590.0 92700.0 0.46 0.7059 0.9968 1700128 ChemDiv1_008018 CCOC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M11 compound treatment 739982.0 149000.0 0.67 760629.0 141000.0 0.7 0.9635 0.9997 1592881 ChemDiv1_008019 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCCN3CCOCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M12 compound treatment 705745.0 114000.0 0.51 728153.0 108000.0 0.54 0.7413 0.9997 1495135 ChemDiv1_008020 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M13 compound treatment 722823.0 131000.0 0.59 777822.0 158000.0 0.78 0.9694 0.9902 1296438 ChemDiv1_008021 CC1CCN(CC1)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M14 compound treatment 734154.0 143000.0 0.64 710558.0 90700.0 0.45 0.7696 0.9851 1454500 ChemDiv1_008022 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccc4F)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M15 compound treatment 762172.0 171000.0 0.76 765564.0 146000.0 0.72 1.051 0.9996 1156342 ChemDiv1_008023 COc1ccc(cc1)N2CCN(CC2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M16 compound treatment 735560.0 144000.0 0.65 746838.0 127000.0 0.63 0.9012 0.9999 1606226 ChemDiv1_008024 Cc1c(sc2ncnc(N3CCc4ccccc4C3)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M17 compound treatment 738278.0 147000.0 0.66 751503.0 132000.0 0.65 0.9261 1.0 1542467 ChemDiv1_008025 CCOC(=O)c1nc(Nc2ccc3OCOc3c2)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M18 compound treatment 748797.0 157000.0 0.7 706598.0 86700.0 0.43 0.8021 0.9718 1388209 ChemDiv1_008026 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)Nc5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M19 compound treatment 741705.0 150000.0 0.67 746815.0 127000.0 0.63 0.9205 0.9994 1319850 ChemDiv1_008027 Cc1c(sc2nc(C)nc(N3CCOCC3)c12)C(=O)Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M20 compound treatment 727417.0 136000.0 0.61 687903.0 68000.0 0.34 0.6689 0.961 1243252 ChemDiv1_008028 CCOC(=O)c1ccccc1NC(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M21 compound treatment 731538.0 140000.0 0.63 734931.0 115000.0 0.57 0.8467 0.9988 1522039 ChemDiv1_008029 CN(C)c1ccc(CN(Cc2ccco2)C(=O)c3sc4nc(C)nc(N5CCOCC5)c4c3C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M22 compound treatment 728219.0 137000.0 0.61 710182.0 90300.0 0.45 0.7495 0.988 1337979 ChemDiv1_008030 CCCCN(C)C(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M23 mock treatment 683424.0 92100.0 0.41 696880.0 77000.0 0.38 0.5611 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 M24 mock treatment 571289.0 -20100.0 -0.09 424314.0 -196000.0 -0.97 -0.7486 -0.7693 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N01 compound treatment 609248.0 17900.0 0.08 545146.0 -74700.0 -0.37 -0.2052 -0.5415 1441255 ChemDiv1_008031 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC6(CC5)OCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N02 compound treatment 619449.0 28100.0 0.13 570661.0 -49200.0 -0.24 -0.0835 -0.3042 1974061 ChemDiv1_008032 COc1ccc(/C=C/2\SC(=O)N(CC(=O)Nc3cccc(O)c3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N03 compound treatment 688309.0 97000.0 0.43 629681.0 9790.0 0.05 0.3412 0.7813 1538226 ChemDiv1_008033 CN1CCN(CC1)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N04 compound treatment 660038.0 68700.0 0.31 599015.0 -20900.0 -0.1 0.1443 0.4448 1927729 ChemDiv1_008034 COc1cc(ccc1O)C2SCC(=O)N2c3c(C)n(C)n(c4ccccc4)c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N05 compound treatment 645639.0 54300.0 0.24 615242.0 -4650.0 -0.02 0.1556 0.6372 1583798 ChemDiv1_008035 C1CN(CCC1N2CCCCCC2)c3ncnc4scc(c5ccccc5)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N06 compound treatment 642462.0 51100.0 0.23 637318.0 17400.0 0.09 0.2228 0.9112 1974062 ChemDiv1_008036 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)NC3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N07 compound treatment 680863.0 89500.0 0.4 674268.0 54400.0 0.27 0.4738 0.9813 1974063 ChemDiv1_008037 Cc1c(sc2ncnc(N3CCc4ccccc4C3)c12)C(=O)N5CCC(CC5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N08 compound treatment 674278.0 82900.0 0.37 679515.0 59600.0 0.3 0.4714 0.9936 1974064 ChemDiv1_008038 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2cc(C)on2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N09 compound treatment 732626.0 141000.0 0.63 639705.0 19800.0 0.1 0.5166 0.8072 1974065 ChemDiv1_008039 CC1CCCCN1c2ncnc3sc(C(=O)Nc4ccc5OCOc5c4)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N10 compound treatment 703671.0 112000.0 0.5 677916.0 58000.0 0.29 0.5588 0.9648 1219654 ChemDiv1_008040 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCc3ccccc3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N11 compound treatment 716655.0 125000.0 0.56 706971.0 87100.0 0.43 0.7017 0.9916 1974066 ChemDiv1_008041 CCN1CCN(CC1)C(=O)CNC(=O)Cn2cnc3SC4CCCCC4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N12 compound treatment 676613.0 85300.0 0.38 674688.0 54800.0 0.27 0.4618 0.9861 1382797 ChemDiv1_008042 CCOc1cc(ccc1OCc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N13 compound treatment 737008.0 146000.0 0.65 713459.0 93600.0 0.46 0.7888 0.986 1974067 ChemDiv1_008043 CCn1c(C(=O)O)c(CC(=O)Nc2ccc(Oc3ccccc3)cc2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N14 compound treatment 660743.0 69400.0 0.31 700386.0 80500.0 0.4 0.5016 0.9924 1298974 ChemDiv1_008044 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N15 compound treatment 697359.0 106000.0 0.47 712494.0 92600.0 0.46 0.6599 0.9999 1974068 ChemDiv1_008045 CCn1c(C(=O)O)c(CC(=O)N2CCC(CC2)(N3CCCCC3)C(=O)N)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N16 compound treatment 707396.0 116000.0 0.52 698096.0 78200.0 0.39 0.6413 0.9896 1153035 ChemDiv1_008046 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N17 compound treatment 746636.0 155000.0 0.7 728984.0 109000.0 0.54 0.8737 0.9923 1974069 ChemDiv1_008047 CCn1c(C(=O)O)c(CC(=O)N(C)c2cc(Cl)c(OC)cc2OC)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N18 compound treatment 757135.0 166000.0 0.74 784201.0 164000.0 0.81 1.1003 0.9989 1552712 ChemDiv1_008048 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N19 compound treatment 729674.0 138000.0 0.62 752599.0 133000.0 0.66 0.9027 0.9996 1974070 ChemDiv1_008049 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N20 compound treatment 723446.0 132000.0 0.59 677178.0 57300.0 0.28 0.6188 0.9434 1974071 ChemDiv1_008050 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N21 compound treatment 709612.0 118000.0 0.53 690902.0 71000.0 0.35 0.6231 0.9803 1431392 ChemDiv1_008051 CCOC(=O)N1CCN(CC1)c2nc(c3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N22 compound treatment 683153.0 91800.0 0.41 691764.0 71900.0 0.36 0.5424 0.9974 1974072 ChemDiv1_008052 COc1cc(cc(OC)c1OC)c2nc(Cl)nc3ccc(Cl)cc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N23 mock treatment 661672.0 70300.0 0.31 664081.0 44200.0 0.22 0.3774 0.9842 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 N24 mock treatment 543289.0 -48100.0 -0.22 157315.0 -463000.0 -2.29 -1.7725 -0.7701 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O01 compound treatment 602599.0 11300.0 0.05 566519.0 -53400.0 -0.26 -0.1513 -0.5623 1974073 ChemDiv1_008053 Cc1ccc(cc1)c2nc(NCc3cccs3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O02 compound treatment 613400.0 22100.0 0.1 586300.0 -33600.0 -0.17 -0.0479 -0.2473 1974074 ChemDiv1_008054 COCCCNC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O03 compound treatment 672726.0 81400.0 0.36 559268.0 -60600.0 -0.3 0.0452 0.0958 1974075 ChemDiv1_008055 [O-][N+](=O)c1ccc(cc1)N2CCN(CC2)c3ncnc4sc5CCCCc5c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O04 compound treatment 632679.0 41300.0 0.19 616264.0 -3630.0 -0.02 0.1181 0.6355 1705377 ChemDiv1_008056 CCOC(=O)C1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccc(OC)cc5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O05 compound treatment 645798.0 54500.0 0.24 652644.0 32800.0 0.16 0.2871 0.9804 1212922 ChemDiv1_008057 CCOC(=O)c1sc2nc(Cc3ccccc3)nc(NCC4CCCO4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O06 compound treatment 648006.0 56700.0 0.25 594124.0 -25800.0 -0.13 0.0891 0.3138 1696292 ChemDiv1_008058 COc1ccc(cc1)N2CCN(CC2)c3ncnc4sc(C(=O)NCc5cccnc5)c(C)c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O07 compound treatment 657698.0 66400.0 0.3 654925.0 35000.0 0.17 0.3327 0.9673 1668837 ChemDiv1_008059 COC(=O)Cc1nc(N2CCN(CC2)c3ccc(F)cc3)c4c(C)c(C)sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O08 compound treatment 688010.0 96700.0 0.43 673530.0 53600.0 0.27 0.4939 0.9726 1974076 ChemDiv1_008060 COc1cc(Cl)c(C)cc1NC(=O)c2sc3ncn(CC(=O)Nc4cccc(c4)C(F)(F)F)c(=O)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O09 compound treatment 677231.0 85900.0 0.38 667149.0 47300.0 0.23 0.4374 0.9717 1137907 ChemDiv1_008061 CCOC(CNc1nc(CC(=O)OC)nc2sc(C(=O)OCC)c(C)c12)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O10 compound treatment 651718.0 60400.0 0.27 641786.0 21900.0 0.11 0.2678 0.9196 1158602 ChemDiv1_008062 Cc1c(sc2ncnc(N3CCN(CC3)c4ccccn4)c12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O11 compound treatment 691080.0 99700.0 0.45 685911.0 66000.0 0.33 0.5469 0.9883 1181323 ChemDiv1_008063 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCc3cccnc3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O12 compound treatment 668916.0 77600.0 0.35 656150.0 36300.0 0.18 0.3725 0.9529 1399136 ChemDiv1_008064 COc1ccccc1N2CCN(CC2)C(=O)c3sc4nc(C)nc(N5CCN(CC5)c6ccccn6)c4c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O13 compound treatment 696413.0 105000.0 0.47 656146.0 36300.0 0.18 0.4596 0.9128 1216335 ChemDiv1_008065 CC1CCCCN1c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O14 compound treatment 691011.0 99700.0 0.45 695283.0 75400.0 0.37 0.5796 0.9961 1712415 ChemDiv1_008066 CC(C)c1ccc(cc1)N(C)c2nc(C)nc3sc(C(=O)O)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O15 compound treatment 728945.0 138000.0 0.62 700987.0 81100.0 0.4 0.7196 0.9786 1974077 ChemDiv1_008067 CCOC(=O)CNC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O16 compound treatment 676134.0 84800.0 0.38 657353.0 37500.0 0.19 0.3996 0.9458 1647692 ChemDiv1_008068 COc1ccccc1N2CCN(CC2)c3nc(CC(=O)O)nc4sc5CCCCc5c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O17 compound treatment 715151.0 124000.0 0.55 703347.0 83500.0 0.41 0.6842 0.9896 1471117 ChemDiv1_008069 CCOC(=O)c1sc2ncnc(N3CCN(CC3)c4ccc(OC)cc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O18 compound treatment 648695.0 57400.0 0.26 692256.0 72400.0 0.36 0.435 0.9866 1360059 ChemDiv1_008070 Cc1c(sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c12)C(=O)N5CCC6(CC5)OCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O19 compound treatment 698712.0 107000.0 0.48 691804.0 71900.0 0.36 0.5917 0.9891 1509379 ChemDiv1_008071 CCN(CC)C(=O)Cn1cnc2sc(C(=O)Nc3nc4ccccc4s3)c(C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O20 compound treatment 681387.0 90000.0 0.4 671579.0 51700.0 0.26 0.4661 0.976 1582645 ChemDiv1_008072 COC(=O)CNC(=O)c1sc2nc(C)nc(N3CCN(CC3)c4ccccn4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O21 compound treatment 701833.0 110000.0 0.49 697208.0 77300.0 0.38 0.6206 0.992 1483510 ChemDiv1_008073 CCOC(=O)c1sc2nc(CC(=O)OC)nc(N3CCCC3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O22 compound treatment 665441.0 74100.0 0.33 665822.0 45900.0 0.23 0.3954 0.9831 1415491 ChemDiv1_008074 CCOC(=O)N1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O23 mock treatment 646548.0 55200.0 0.25 667813.0 47900.0 0.24 0.3426 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 O24 mock treatment 416399.0 -175000.0 -0.78 88367.0 -532000.0 -2.63 -2.4156 -0.8793 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P01 compound treatment 564636.0 -26700.0 -0.12 517159.0 -103000.0 -0.51 -0.4444 -0.8501 1280854 ChemDiv1_008075 CCN1CCN(CC1)C(=O)c2sc3ncnc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P02 compound treatment 582397.0 -8950.0 -0.04 540919.0 -79000.0 -0.39 -0.3049 -0.7754 1974078 ChemDiv1_008076 COc1ccc(/C=C/2\SC(=O)N(CCCC(=O)N3CCOCC3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P03 compound treatment 606212.0 14900.0 0.07 576302.0 -43600.0 -0.22 -0.1056 -0.4675 1297433 ChemDiv1_008077 CCOC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P04 compound treatment 615234.0 23900.0 0.11 573322.0 -46600.0 -0.23 -0.0875 -0.3441 1926655 ChemDiv1_008078 Cc1c(N2C(SCC2=O)c3ccccc3Cl)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P05 compound treatment 619174.0 27800.0 0.12 575086.0 -44800.0 -0.22 -0.0689 -0.2705 1565563 ChemDiv1_008079 CCCN1CCN(CC1)C(=O)c2sc3nc(C)nc(N4CCN(CC4)c5ccccn5)c3c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P06 compound treatment 628676.0 37300.0 0.17 588662.0 -31200.0 -0.15 0.0088 0.0385 1974079 ChemDiv1_008080 Cc1ccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P07 compound treatment 665969.0 74600.0 0.33 584570.0 -35300.0 -0.17 0.1125 0.2983 1623167 ChemDiv1_008081 CC1CCCCN1C(=O)Cn2cnc3sc(C(=O)O)c(C)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P08 compound treatment 612679.0 21300.0 0.1 589179.0 -30700.0 -0.15 -0.0401 -0.223 1974080 ChemDiv1_008082 Cc1cc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P09 compound treatment 648690.0 57300.0 0.26 599894.0 -20000.0 -0.1 0.1115 0.4051 1974081 ChemDiv1_008083 CCN(CC)CCCNC(=O)c1sc2ncnc(N3CCCCC3C)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P10 compound treatment 640959.0 49600.0 0.22 619584.0 -307.0 0.0 0.156 0.7022 1482356 ChemDiv1_008084 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P11 compound treatment 663204.0 71900.0 0.32 607150.0 -12700.0 -0.06 0.1828 0.5577 1974082 ChemDiv1_008085 CC1CCCCN1c2ncnc3sc(C(=O)N4CCC5(CC4)OCCO5)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P12 compound treatment 620928.0 29600.0 0.13 608486.0 -11400.0 -0.06 0.0537 0.3729 1279826 ChemDiv1_008086 COc1ccc(cc1OCc2ccc(Cl)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P13 compound treatment 640516.0 49200.0 0.22 625006.0 5120.0 0.03 0.1736 0.7833 1974083 ChemDiv1_008087 CCn1c(C(=O)O)c(CC(=O)Nc2cc(OC)c(OC)c(OC)c2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P14 compound treatment 645090.0 53700.0 0.24 611386.0 -8500.0 -0.04 0.1403 0.5745 1201686 ChemDiv1_008088 COc1ccc(cc1)C2CC(=NN2C(=O)C)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P15 compound treatment 663871.0 72500.0 0.32 640980.0 21100.0 0.1 0.3034 0.8897 1974084 ChemDiv1_008089 CCn1c(C(=O)O)c(CC(=O)N2CCC(Cc3ccccc3)CC2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P16 compound treatment 676281.0 84900.0 0.38 644944.0 25100.0 0.12 0.3566 0.8916 1585727 ChemDiv1_008090 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P17 compound treatment 641944.0 50600.0 0.23 648996.0 29100.0 0.14 0.2621 0.9762 1974085 ChemDiv1_008091 CCN(CCCNC(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P18 compound treatment 696704.0 105000.0 0.47 658745.0 38900.0 0.19 0.4696 0.9219 1540312 ChemDiv1_008092 COc1ccc(cc1OC)C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P19 compound treatment 661064.0 69700.0 0.31 626158.0 6270.0 0.03 0.2426 0.7736 1140554 ChemDiv1_008093 OC(=O)C1CCCN1c2nc(c3ccccc3)c4cc(Br)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P20 compound treatment 703589.0 112000.0 0.5 678956.0 59100.0 0.29 0.5622 0.9669 1974086 ChemDiv1_008094 COc1ccc(cc1OC)C2CC(=NN2C(=O)c3cc(OC)c(OC)c(OC)c3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P21 compound treatment 642792.0 51400.0 0.23 667804.0 47900.0 0.24 0.3307 0.9999 1383273 ChemDiv1_008095 Cc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)CC5(CC(=O)O)CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P22 compound treatment 633822.0 42500.0 0.19 627531.0 7640.0 0.04 0.1612 0.8315 1974087 ChemDiv1_008096 CC(C)(C)NC(=O)CSc1nc[nH]n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P23 mock treatment 589139.0 -2210.0 -0.01 630974.0 11100.0 0.05 0.0318 0.5708 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.609 P24 mock treatment 499281.0 -92100.0 -0.41 178787.0 -441000.0 -2.19 -1.8365 -0.8259 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A01 compound treatment 635065.0 28800.0 0.13 581221.0 13500.0 0.07 0.1384 0.9527 1974088 ChemDiv1_008449 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccn3)C(=O)Nc4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A02 compound treatment 608721.0 2490.0 0.01 554463.0 -13300.0 -0.07 -0.0387 -0.5795 1974089 ChemDiv1_008450 Clc1ccc(Cl)c(NC(=O)CSc2nnc3sc4ccccc4n23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A03 compound treatment 612570.0 6340.0 0.03 586450.0 18700.0 0.09 0.0855 0.8833 1544275 ChemDiv1_008451 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)Nc6ccccc6F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A04 compound treatment 645293.0 39100.0 0.17 586051.0 18300.0 0.09 0.1877 0.9531 1477326 ChemDiv1_008452 Cc1ccc(cc1)c2nnc(Oc3ccc(OCc4ccccc4)cc3)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A05 compound treatment 662931.0 56700.0 0.25 613321.0 45600.0 0.23 0.339 0.9983 1386052 ChemDiv1_008453 Cc1c(NC(=O)COc2ccc(cc2)C3CCCCC3)cccc1c4nc5ncccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A06 compound treatment 653201.0 47000.0 0.21 626720.0 59000.0 0.29 0.3552 0.987 1540980 ChemDiv1_008454 C=CCn1c(CSc2nc3ccccc3s2)nnc1SCC(=O)NCc4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A07 compound treatment 694863.0 88600.0 0.4 625781.0 58000.0 0.29 0.4837 0.9875 1928670 ChemDiv1_008455 COc1ccc(cc1)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A08 compound treatment 681936.0 75700.0 0.34 637836.0 70100.0 0.35 0.4851 0.9999 1499095 ChemDiv1_008456 COc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A09 compound treatment 690491.0 84300.0 0.38 644728.0 77000.0 0.38 0.5363 1.0 1974090 ChemDiv1_008457 OC(=O)COc1ccc(Br)cc1/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A10 compound treatment 663455.0 57200.0 0.26 636919.0 69200.0 0.34 0.4233 0.9897 1359187 ChemDiv1_008458 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A11 compound treatment 692201.0 86000.0 0.38 639099.0 71300.0 0.35 0.522 0.9991 1552112 ChemDiv1_008459 C1CCC2(CC1)C3=C(CCCC3)Nc4ncnn42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A12 compound treatment 698358.0 92100.0 0.41 636817.0 69000.0 0.34 0.5335 0.9957 1974091 ChemDiv1_008460 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A13 compound treatment 699107.0 92900.0 0.42 640346.0 72600.0 0.36 0.5482 0.9974 1528870 ChemDiv1_008461 CC1Oc2ccccc2OC1C(=O)NCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A14 compound treatment 709075.0 103000.0 0.46 637950.0 70200.0 0.35 0.5714 0.9904 1663296 ChemDiv1_008462 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(cc3)N(C)C)C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A15 compound treatment 688653.0 82400.0 0.37 639481.0 71700.0 0.36 0.5121 0.9998 1692728 ChemDiv1_008463 COc1cc(cc(OC)c1OC)C2N(C(=O)CCC(=O)O)c3ccccc3NC4=C2C(=O)CC(C4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A16 compound treatment 727253.0 121000.0 0.54 666991.0 99200.0 0.49 0.7306 0.9988 1974092 ChemDiv1_008464 Fc1ccc(cc1)C2CC(=NN2C(=O)c3ccncc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A17 compound treatment 681633.0 75400.0 0.34 633943.0 66200.0 0.33 0.4705 0.9999 1974093 ChemDiv1_008465 Nc1nc(Nc2ccc(cc2)[N+](=O)[O-])nc(n1)c3ccc(o3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A18 compound treatment 726847.0 121000.0 0.54 671639.0 104000.0 0.51 0.7456 0.9997 1614824 ChemDiv1_008466 COc1ccc(C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A19 compound treatment 670855.0 64600.0 0.29 616338.0 48600.0 0.24 0.3747 0.9958 1428667 ChemDiv1_008467 Cc1csc(=Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A20 compound treatment 652728.0 46500.0 0.21 608406.0 40600.0 0.2 0.2895 0.9999 1974094 ChemDiv1_008468 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A21 compound treatment 643370.0 37100.0 0.17 612337.0 44600.0 0.22 0.2737 0.9902 1974095 ChemDiv1_008469 COC(=O)c1ccc(cc1)n2c(C)cc(C(=O)CSc3nnc4ccccn34)c2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A22 compound treatment 630261.0 24000.0 0.11 601836.0 34100.0 0.17 0.1954 0.9763 1974096 ChemDiv1_008470 COc1cc(OC)c(cc1/C=C\2/C(=O)NC(=O)N(C2=O)c3cccc(C)c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A23 mock treatment 598202.0 -8030.0 -0.04 580316.0 12500.0 0.06 0.0185 0.258 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 A24 mock treatment 490927.0 -115000.0 -0.52 505541.0 -62200.0 -0.31 -0.583 -0.9696 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B01 compound treatment 630294.0 24100.0 0.11 596047.0 28300.0 0.14 0.1752 0.9916 1974097 ChemDiv1_008471 CCOC(=O)c1ccc(cc1)c2ccc(/C=C\3/C(=O)NC(=S)N(C3=O)c4ccc(OC)cc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B02 compound treatment 657250.0 51000.0 0.23 603633.0 35900.0 0.18 0.2871 0.9923 1974098 ChemDiv1_008472 Nc1nc(SCCBr)c(C#N)c(c1C#N)c2cccc(Cl)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B03 compound treatment 719627.0 113000.0 0.51 717347.0 150000.0 0.74 0.8829 0.983 1974099 ChemDiv1_008473 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B04 compound treatment 680570.0 74300.0 0.33 667989.0 100000.0 0.5 0.5864 0.9811 1686533 ChemDiv1_008474 CCCC(=O)Nc1nc(S)c(C#N)c(c1C#N)c2ccc(OC(=O)CCC)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B05 compound treatment 745592.0 139000.0 0.62 729789.0 162000.0 0.8 1.0086 0.9922 1207889 ChemDiv1_008475 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B06 compound treatment 785465.0 179000.0 0.8 734165.0 166000.0 0.82 1.1502 0.9999 1974100 ChemDiv1_008476 COc1ccc(cc1)N2C(=O)/C(=C/c3cn(Cc4ccccc4)c5ccccc35)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B07 compound treatment 780559.0 174000.0 0.78 804451.0 237000.0 1.17 1.3809 0.9804 1357613 ChemDiv1_008477 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)c(OC)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B08 compound treatment 767580.0 161000.0 0.72 747677.0 180000.0 0.89 1.1409 0.9946 1974101 ChemDiv1_008478 CCOc1cc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B09 compound treatment 738045.0 132000.0 0.59 714511.0 147000.0 0.73 0.9312 0.9946 1974102 ChemDiv1_008479 CN(C)c1cc(Nc2cc(C)ccc2C)c([N+](=O)[O-])c3nonc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B10 compound treatment 744452.0 138000.0 0.62 704638.0 137000.0 0.68 0.9169 0.999 1974103 ChemDiv1_008480 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B11 compound treatment 742984.0 137000.0 0.61 707904.0 140000.0 0.69 0.9237 0.998 1974104 ChemDiv1_008481 Cc1c(Nc2cc(N3CCCCCC3)c4nonc4c2[N+](=O)[O-])c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B12 compound treatment 690442.0 84200.0 0.38 692852.0 125000.0 0.62 0.7047 0.9716 1974105 ChemDiv1_008482 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(Cl)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B13 compound treatment 738741.0 133000.0 0.59 699482.0 132000.0 0.65 0.8808 0.9989 1296376 ChemDiv1_008483 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3sc4CCCCCc4c3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B14 compound treatment 736986.0 131000.0 0.59 688555.0 121000.0 0.6 0.837 0.9999 1974106 ChemDiv1_008484 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B15 compound treatment 762298.0 156000.0 0.7 733651.0 166000.0 0.82 1.0751 0.9967 1592915 ChemDiv1_008485 CCC(NC(=O)c1ccccc1NC(=O)c2ccccc2)C(=O)N3CCN(C)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B16 compound treatment 745563.0 139000.0 0.62 705673.0 138000.0 0.68 0.9241 0.999 1974107 ChemDiv1_008486 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B17 compound treatment 755463.0 149000.0 0.67 709925.0 142000.0 0.7 0.9703 0.9997 1374906 ChemDiv1_008487 Brc1ccc(cc1)C(=O)C2Oc3ccccc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B18 compound treatment 703999.0 97800.0 0.44 662891.0 95100.0 0.47 0.6427 0.9993 1974108 ChemDiv1_008488 [O-][N+](=O)c1cnc(NC(=O)/C=C/c2ccc3OCOc3c2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B19 compound treatment 728796.0 123000.0 0.55 691412.0 124000.0 0.61 0.821 0.9985 1143441 ChemDiv1_008489 Nc1c(sc2nc3CCCCCc3cc12)C(=O)Nc4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B20 compound treatment 687898.0 81700.0 0.37 673849.0 106000.0 0.53 0.6301 0.9843 1974109 ChemDiv1_008490 Cc1[nH]c(=O)[nH]c(=O)c1CSCC(=O)OCC(=O)Nc2nc3CC(C)(C)CC(=O)c3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B21 compound treatment 736328.0 130000.0 0.58 671663.0 104000.0 0.51 0.7757 0.9981 1484624 ChemDiv1_008491 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SCC)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B22 compound treatment 662785.0 56600.0 0.25 623734.0 56000.0 0.28 0.375 0.999 1715169 ChemDiv1_008492 Cc1ccccc1Cn2c(NC(=O)C3CCCCC3)nc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B23 mock treatment 689362.0 83100.0 0.37 652428.0 84700.0 0.42 0.5597 0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 B24 mock treatment 539833.0 -66400.0 -0.3 487064.0 -80700.0 -0.4 -0.4929 -0.9893 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C01 compound treatment 641441.0 35200.0 0.16 562198.0 -5570.0 -0.03 0.0919 0.5746 1974110 ChemDiv1_008493 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C02 compound treatment 673139.0 66900.0 0.3 604313.0 36500.0 0.18 0.3398 0.9709 1974111 ChemDiv1_008494 Cc1cc2nnc(SCC(=O)Nc3cc(Cl)ccc3Cl)n2c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C03 compound treatment 720325.0 114000.0 0.51 637386.0 69600.0 0.34 0.605 0.9817 1669602 ChemDiv1_008495 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)Nc6cccc(F)c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C04 compound treatment 708237.0 102000.0 0.46 663510.0 95700.0 0.47 0.6582 0.9998 1974112 ChemDiv1_008496 CC(C)(C)c1ccc(cc1)c2nc3scc(c4ccccc4)c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C05 compound treatment 717305.0 111000.0 0.5 674386.0 107000.0 0.53 0.725 0.9995 1974113 ChemDiv1_008497 Cn1c(SCC(=O)O)nnc1c2ccc(N)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C06 compound treatment 696372.0 90100.0 0.4 684806.0 117000.0 0.58 0.6953 0.9843 1717998 ChemDiv1_008498 COc1ccc(OC)c(c1)C2SCCN2C(=O)c3cc4cc(Br)ccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C07 compound treatment 773550.0 167000.0 0.75 693954.0 126000.0 0.63 0.9716 0.996 1923328 ChemDiv1_008499 COc1ccc(cc1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C08 compound treatment 752506.0 146000.0 0.65 715262.0 147000.0 0.73 0.9796 0.9985 1468656 ChemDiv1_008500 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C09 compound treatment 792927.0 187000.0 0.84 723159.0 155000.0 0.77 1.1352 0.9992 1974114 ChemDiv1_008501 Cc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(C)n1c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C10 compound treatment 755399.0 149000.0 0.67 693704.0 126000.0 0.62 0.9133 0.9994 1197620 ChemDiv1_008502 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C11 compound treatment 770874.0 165000.0 0.74 745315.0 178000.0 0.88 1.1431 0.9961 1974115 ChemDiv1_008503 FS(=O)(=O)c1ccc(cc1)C2=CC(c3ccccc3)n4ncnc4N2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C12 compound treatment 765990.0 160000.0 0.72 710585.0 143000.0 0.71 1.0059 1.0 1974116 ChemDiv1_008504 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C13 compound treatment 765972.0 160000.0 0.72 726492.0 159000.0 0.79 1.0616 0.9989 1465719 ChemDiv1_008505 CCOC(=O)c1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C14 compound treatment 770424.0 164000.0 0.73 706986.0 139000.0 0.69 1.0074 0.9995 1974117 ChemDiv1_008506 COc1ccc(cc1)C2CC(=NN2C(=O)c3ccccc3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C15 compound treatment 803065.0 197000.0 0.88 765661.0 198000.0 0.98 1.3162 0.9986 1974118 ChemDiv1_008507 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5cccs5)C(=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C16 compound treatment 755967.0 150000.0 0.67 701649.0 134000.0 0.66 0.9429 1.0 1974119 ChemDiv1_008508 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)c4ccncc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C17 compound treatment 798156.0 192000.0 0.86 705652.0 138000.0 0.68 1.0905 0.9935 1974120 ChemDiv1_008509 Nc1nc(Nc2ccc(Cl)cc2)nc(n1)c3ccc(o3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C18 compound treatment 741471.0 135000.0 0.61 665965.0 98200.0 0.49 0.772 0.9941 1097891 ChemDiv1_008510 OC1(CC(=O)c2ccccn2)C(=O)Nc3ccccc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C19 compound treatment 734859.0 129000.0 0.58 681417.0 114000.0 0.56 0.8052 0.9999 1974121 ChemDiv1_008511 OCCN1CCN(CC1)C(=O)CSc2nnc(CCN3C(=O)c4cccc5cccc(C3=O)c45)n2c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C20 compound treatment 732231.0 126000.0 0.56 654748.0 87000.0 0.43 0.7035 0.9912 1974122 ChemDiv1_008512 O=C(Oc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5cccc6ccccc56)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C21 compound treatment 684040.0 77800.0 0.35 685026.0 117000.0 0.58 0.657 0.9701 1974123 ChemDiv1_008513 CCOC(=O)c1sc(NC(=O)CSc2ncnc3sc(C)c(C)c23)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C22 compound treatment 663565.0 57300.0 0.26 624755.0 57000.0 0.28 0.3811 0.9989 1974124 ChemDiv1_008514 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Br)c(O)c(c3)[N+](=O)[O-])/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C23 mock treatment 689647.0 83400.0 0.37 669305.0 102000.0 0.5 0.6197 0.9892 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 C24 mock treatment 522890.0 -83300.0 -0.37 517652.0 -50100.0 -0.25 -0.4394 -0.9804 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D01 compound treatment 642984.0 36800.0 0.16 619282.0 51500.0 0.26 0.2968 0.9774 1974125 ChemDiv1_008515 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(O)c(Br)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D02 compound treatment 648690.0 42500.0 0.19 612551.0 44800.0 0.22 0.2913 0.997 1974126 ChemDiv1_008516 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(O)c(O)c3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D03 compound treatment 871475.0 265000.0 1.19 792960.0 225000.0 1.12 1.6284 0.9995 1974127 ChemDiv1_008517 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C/c3cc(Cl)c(O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D04 compound treatment 709868.0 104000.0 0.46 662794.0 95000.0 0.47 0.6609 1.0 1486303 ChemDiv1_008518 Nc1c(sc2nc(N)c(C#N)c(c3ccc(O)cc3)c12)C(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D05 compound treatment 1684785.0 1080000.0 4.83 1694048.0 1130000.0 5.58 7.3591 0.9974 1580854 ChemDiv1_008519 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D06 compound treatment 7196796.0 6590000.0 29.5 6948025.0 6380000.0 31.61 43.2102 0.9994 1974128 ChemDiv1_008520 CCN(CC)c1ccc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D07 compound treatment 873526.0 267000.0 1.2 831202.0 263000.0 1.3 1.7688 0.9991 1338851 ChemDiv1_008521 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D08 compound treatment 768467.0 162000.0 0.73 754418.0 187000.0 0.92 1.1673 0.9929 1514082 ChemDiv1_008522 CC1=C(C(NC(=O)N1)c2cc3OCOc3cc2Br)C(=O)OCc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D09 compound treatment 726985.0 121000.0 0.54 705121.0 137000.0 0.68 0.8633 0.9935 1974129 ChemDiv1_008523 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D10 compound treatment 742744.0 137000.0 0.61 709414.0 142000.0 0.7 0.9283 0.9976 1974130 ChemDiv1_008524 CC(C)OCCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCc3ccccc3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D11 compound treatment 780459.0 174000.0 0.78 741973.0 174000.0 0.86 1.1617 0.9987 1974131 ChemDiv1_008525 [O-][N+](=O)c1c(NCc2ccccc2)cc(N3CCCCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D12 compound treatment 694148.0 87900.0 0.39 669515.0 102000.0 0.5 0.6347 0.9925 1974132 ChemDiv1_008526 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D13 compound treatment 771849.0 166000.0 0.74 748287.0 181000.0 0.89 1.1566 0.9957 1320542 ChemDiv1_008527 CC1(C)Cc2c(sc3ncn4nc(Cc5ccccc5)nc4c23)C(C)(C)N1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D14 compound treatment 744154.0 138000.0 0.62 662658.0 94900.0 0.47 0.7689 0.9909 1416253 ChemDiv1_008528 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OCC)c3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D15 compound treatment 790238.0 184000.0 0.82 753329.0 186000.0 0.92 1.2324 0.9985 1686441 ChemDiv1_008529 CN1CCN(CC1)C(=O)C(Cc2ccccc2)NC(=O)c3ccccc3NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D16 compound treatment 737087.0 131000.0 0.59 708320.0 141000.0 0.7 0.9065 0.9963 1190119 ChemDiv1_008530 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)OC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D17 compound treatment 777295.0 171000.0 0.77 740164.0 172000.0 0.85 1.1453 0.9985 1543171 ChemDiv1_008531 COc1ccc(cc1)C2=NN3C(C2)c4ccccc4OC3C(=O)c5ccc(Br)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D18 compound treatment 725481.0 119000.0 0.53 699224.0 131000.0 0.65 0.8379 0.9951 1633665 ChemDiv1_008532 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D19 compound treatment 732192.0 126000.0 0.56 708190.0 140000.0 0.7 0.8906 0.9946 1644998 ChemDiv1_008533 Nc1c(sc2nc3CCCCc3cc12)C(=O)Nc4ccc5ccccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D20 compound treatment 761059.0 155000.0 0.69 669811.0 102000.0 0.51 0.8475 0.988 1974133 ChemDiv1_008534 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C4(CC5CC6CC(C5)C4)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D21 compound treatment 736254.0 130000.0 0.58 684593.0 117000.0 0.58 0.8208 1.0 1137703 ChemDiv1_008535 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SC)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D22 compound treatment 693938.0 87700.0 0.39 657720.0 90000.0 0.45 0.5927 0.998 1450518 ChemDiv1_008536 O=C(Nc1nc2ccccc2n1CCN3CCCC3)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D23 mock treatment 687898.0 81700.0 0.37 662745.0 95000.0 0.47 0.5912 0.9922 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 D24 mock treatment 566416.0 -39800.0 -0.18 514816.0 -53000.0 -0.26 -0.3115 -0.9823 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E01 compound treatment 652574.0 46300.0 0.21 595209.0 27400.0 0.14 0.2428 0.979 1974134 ChemDiv1_008537 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E02 compound treatment 657206.0 51000.0 0.23 635341.0 67600.0 0.33 0.398 0.9825 1974135 ChemDiv1_008538 Cc1nc(SCC(=O)Nc2sc3CCCc3c2C(=O)N)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E03 compound treatment 729006.0 123000.0 0.55 685025.0 117000.0 0.58 0.7993 0.9996 1974136 ChemDiv1_008539 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E04 compound treatment 719702.0 113000.0 0.51 670962.0 103000.0 0.51 0.7206 1.0 1974137 ChemDiv1_008540 CC(C)(C)c1ccc(cc1)c2nc3sc4CCCc4c3c(=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E05 compound treatment 757064.0 151000.0 0.68 726579.0 159000.0 0.79 1.0337 0.9971 1554138 ChemDiv1_008541 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)c4ccc(Cl)cc4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E06 compound treatment 714161.0 108000.0 0.48 717758.0 150000.0 0.74 0.867 0.9783 1289342 ChemDiv1_008542 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E07 compound treatment 763904.0 158000.0 0.71 750826.0 183000.0 0.91 1.1403 0.9923 1923360 ChemDiv1_008543 COc1ccc(cc1)N(CC(=O)Nc2cc(OC)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E08 compound treatment 770124.0 164000.0 0.73 693409.0 126000.0 0.62 0.9589 0.9967 1267641 ChemDiv1_008544 COc1ccc(OC)c(c1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E09 compound treatment 788701.0 182000.0 0.82 742059.0 174000.0 0.86 1.1881 0.9996 1974138 ChemDiv1_008545 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E10 compound treatment 766824.0 161000.0 0.72 744400.0 177000.0 0.87 1.127 0.9952 1640155 ChemDiv1_008546 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E11 compound treatment 780364.0 174000.0 0.78 763451.0 196000.0 0.97 1.2366 0.9942 1974139 ChemDiv1_008547 Clc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(Cl)cc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E12 compound treatment 771163.0 165000.0 0.74 748681.0 181000.0 0.9 1.1558 0.9954 1974140 ChemDiv1_008548 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E13 compound treatment 755819.0 150000.0 0.67 754495.0 187000.0 0.93 1.1276 0.9874 1205423 ChemDiv1_008549 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc(Cl)c(Cl)c3)c4ccc(O)c(O)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E14 compound treatment 743305.0 137000.0 0.61 716149.0 148000.0 0.74 0.9536 0.996 1633266 ChemDiv1_008550 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccccc4nc3Cl)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E15 compound treatment 812519.0 206000.0 0.92 756352.0 189000.0 0.93 1.3135 1.0 1714137 ChemDiv1_008551 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5cccs5)C(=O)c6cc(OC)c(OC)c(OC)c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E16 compound treatment 775215.0 169000.0 0.76 725274.0 158000.0 0.78 1.0866 0.9999 1974141 ChemDiv1_008552 COc1ccccc1C2CC(=NN2C(=O)c3ccncc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E17 compound treatment 778155.0 172000.0 0.77 726853.0 159000.0 0.79 1.1014 0.9999 1974142 ChemDiv1_008553 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCc2c[nH]c3ccccc23)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E18 compound treatment 753516.0 147000.0 0.66 685332.0 118000.0 0.58 0.878 0.9981 1130606 ChemDiv1_008554 Cn1c(SCC(=O)NC2CCCCC2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E19 compound treatment 756584.0 150000.0 0.67 696322.0 129000.0 0.64 0.9262 0.9996 1974143 ChemDiv1_008555 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)NCCN4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E20 compound treatment 726765.0 121000.0 0.54 687290.0 120000.0 0.59 0.8002 0.9989 1676953 ChemDiv1_008556 CCOC(=O)N1C(=O)c2cc(OC)ccc2S1(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E21 compound treatment 720911.0 115000.0 0.51 701670.0 134000.0 0.66 0.832 0.992 1974144 ChemDiv1_008557 Cc1sc2nc(/C=C/c3ccco3)oc(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E22 compound treatment 741158.0 135000.0 0.6 664987.0 97200.0 0.48 0.7676 0.9937 1974145 ChemDiv1_008558 COC(=O)Cn1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E23 mock treatment 719787.0 114000.0 0.51 667735.0 100000.0 0.5 0.7096 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 E24 mock treatment 538086.0 -68100.0 -0.31 543850.0 -23900.0 -0.12 -0.2995 -0.9151 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F01 compound treatment 616961.0 10700.0 0.05 572289.0 4520.0 0.02 0.0498 0.9397 1974146 ChemDiv1_008559 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(o3)c4ccccc4[N+](=O)[O-])/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F02 compound treatment 660124.0 53900.0 0.24 615768.0 48000.0 0.24 0.3387 1.0 1974147 ChemDiv1_008560 Nc1nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c(C#N)c(Cc3ccccc3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F03 compound treatment 727149.0 121000.0 0.54 661055.0 93300.0 0.46 0.7095 0.9969 1974148 ChemDiv1_008561 OC(=O)Cn1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3F)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F04 compound treatment 734299.0 128000.0 0.57 703245.0 135000.0 0.67 0.8799 0.9969 1143186 ChemDiv1_008562 COc1cc(c(Cl)cc1O)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F05 compound treatment 757338.0 151000.0 0.68 734964.0 167000.0 0.83 1.064 0.9949 1378478 ChemDiv1_008563 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(O)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F06 compound treatment 709320.0 103000.0 0.46 682303.0 115000.0 0.57 0.7275 0.9947 1974149 ChemDiv1_008564 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCc4ccc(cc4)C(=O)O)cc3)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F07 compound treatment 726093.0 120000.0 0.54 727489.0 160000.0 0.79 0.9389 0.9821 1627524 ChemDiv1_008565 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F08 compound treatment 744354.0 138000.0 0.62 702912.0 135000.0 0.67 0.9106 0.9992 1974150 ChemDiv1_008566 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F09 compound treatment 748338.0 142000.0 0.64 727933.0 160000.0 0.79 1.0108 0.994 1974151 ChemDiv1_008567 Cc1ccc(Nc2cc(N3CCCCC3)c4nonc4c2[N+](=O)[O-])c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F10 compound treatment 697218.0 91000.0 0.41 719562.0 152000.0 0.75 0.8197 0.9585 1974152 ChemDiv1_008568 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F11 compound treatment 747973.0 142000.0 0.63 675528.0 108000.0 0.53 0.8261 0.9963 1974153 ChemDiv1_008569 Oc1ccc(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F12 compound treatment 739171.0 133000.0 0.6 695699.0 128000.0 0.63 0.8689 0.9995 1974154 ChemDiv1_008570 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F13 compound treatment 744556.0 138000.0 0.62 732209.0 164000.0 0.81 1.0138 0.9908 1650532 ChemDiv1_008571 COc1ccccc1c2nc3c4c5CC(C)(C)NC(C)(C)c5sc4ncn3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F14 compound treatment 753670.0 147000.0 0.66 692504.0 125000.0 0.62 0.9036 0.9995 1167672 ChemDiv1_008572 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)ccc4OC)C(=O)OCC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F15 compound treatment 760513.0 154000.0 0.69 715565.0 148000.0 0.73 1.006 0.9996 1526810 ChemDiv1_008573 Cc1ccnc(c1)n2c(CCCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F16 compound treatment 741619.0 135000.0 0.61 705808.0 138000.0 0.68 0.9121 0.9982 1974155 ChemDiv1_008574 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F17 compound treatment 795096.0 189000.0 0.85 753199.0 185000.0 0.92 1.2473 0.9991 1461307 ChemDiv1_008575 COc1ccccc1C2Oc3ccc(Cl)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F18 compound treatment 724131.0 118000.0 0.53 658322.0 90600.0 0.45 0.6904 0.9967 1717441 ChemDiv1_008576 CN(C(=O)C)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F19 compound treatment 677203.0 71000.0 0.32 663241.0 95500.0 0.47 0.5591 0.9813 1974156 ChemDiv1_008577 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4cc(ccc4Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F20 compound treatment 717497.0 111000.0 0.5 651252.0 83500.0 0.41 0.6446 0.9957 1974157 ChemDiv1_008578 O=C(COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C3(CC4CC5CC(C4)C3)C5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F21 compound treatment 717453.0 111000.0 0.5 695104.0 127000.0 0.63 0.7981 0.9931 1974158 ChemDiv1_008579 CCCCOC(=O)CSC1=C(C#N)C(C(=C(N1)c2ccccc2)C(=O)OCC)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F22 compound treatment 695148.0 88900.0 0.4 636221.0 68500.0 0.34 0.5212 0.9968 1500655 ChemDiv1_008580 O=C(Nc1nc2ccccc2n1CCN3CCCCC3)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F23 mock treatment 694953.0 88700.0 0.4 660829.0 93100.0 0.46 0.6068 0.9972 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 F24 mock treatment 511498.0 -94700.0 -0.42 517480.0 -50300.0 -0.25 -0.476 -0.9678 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G01 compound treatment 631449.0 25200.0 0.11 566705.0 -1060.0 -0.01 0.0761 0.6734 1974159 ChemDiv1_008581 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G02 compound treatment 680451.0 74200.0 0.33 633318.0 65500.0 0.32 0.4645 0.9999 1472611 ChemDiv1_008582 CC(=O)Nc1cccc(Oc2nnc(c3ccc(C)c(C)c3)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G03 compound treatment 714220.0 108000.0 0.48 659379.0 91600.0 0.45 0.6627 0.9995 1204046 ChemDiv1_008583 COc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G04 compound treatment 725585.0 119000.0 0.53 657487.0 89700.0 0.44 0.6921 0.9958 1648336 ChemDiv1_008584 C=CCn1c(SCC(=O)NC2CCCCC2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G05 compound treatment 752611.0 146000.0 0.66 708195.0 140000.0 0.7 0.9552 0.9996 1974160 ChemDiv1_008585 CN(CCOC(=O)c1ccc2OCCOc2c1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G06 compound treatment 738367.0 132000.0 0.59 701751.0 134000.0 0.66 0.8876 0.9983 1675890 ChemDiv1_008586 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G07 compound treatment 4611881.0 4010000.0 17.93 4810107.0 4240000.0 21.02 27.5393 0.9969 1974161 ChemDiv1_008587 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(Br)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G08 compound treatment 761203.0 155000.0 0.69 723474.0 156000.0 0.77 1.0359 0.9986 1146967 ChemDiv1_008588 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G09 compound treatment 793312.0 187000.0 0.84 731354.0 164000.0 0.81 1.1652 0.9999 1974162 ChemDiv1_008589 CCOc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)ccc1OCC(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G10 compound treatment 765291.0 159000.0 0.71 698147.0 130000.0 0.65 0.9602 0.9988 1974163 ChemDiv1_008590 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G11 compound treatment 776638.0 170000.0 0.76 728781.0 161000.0 0.8 1.1034 0.9998 1865646 ChemDiv1_008591 Fc1ccc(/C=C/2\CCCC3=C2Nc4ncnn4C3c5ccc(F)cc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G12 compound treatment 754861.0 149000.0 0.67 725306.0 158000.0 0.78 1.0223 0.9968 1974164 ChemDiv1_008592 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(F)cc3)C(=O)c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G13 compound treatment 783819.0 178000.0 0.79 753028.0 185000.0 0.92 1.211 0.9974 1553890 ChemDiv1_008593 COc1cc(ccc1O)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(Cl)c(Cl)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G14 compound treatment 775109.0 169000.0 0.76 733133.0 165000.0 0.82 1.1138 0.9992 1287317 ChemDiv1_008594 COc1ccc(cc1OC)C2=NN(C(C2)c3cc4ccccc4nc3Cl)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G15 compound treatment 810118.0 204000.0 0.91 761853.0 194000.0 0.96 1.3252 0.9997 1513887 ChemDiv1_008595 COc1cccc(c1)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C4)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G16 compound treatment 777189.0 171000.0 0.77 723214.0 155000.0 0.77 1.0856 1.0 1224926 ChemDiv1_008596 Fc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G17 compound treatment 788856.0 183000.0 0.82 742796.0 175000.0 0.87 1.1911 0.9996 1232850 ChemDiv1_008597 COc1ccc(CCN2C(Nc3ccccc3C2=O)c4ccc(cc4)N(C)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G18 compound treatment 778411.0 172000.0 0.77 698712.0 131000.0 0.65 1.0037 0.9963 1172732 ChemDiv1_008598 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(OC(C)C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G19 compound treatment 764581.0 158000.0 0.71 722823.0 155000.0 0.77 1.0443 0.9992 1974165 ChemDiv1_008599 OCCCNC(=O)CSc1nnc(CCN2C(=O)c3cccc4cccc(C2=O)c34)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G20 compound treatment 736294.0 130000.0 0.58 662945.0 95200.0 0.47 0.7451 0.9945 1544594 ChemDiv1_008600 CCOC(=O)N1C(=O)c2cc(OCC)ccc2S1(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G21 compound treatment 747944.0 142000.0 0.63 669138.0 101000.0 0.5 0.8036 0.9933 1974166 ChemDiv1_008601 Cc1nc(SCC(=O)Nc2ccccc2F)c3c4CCCCc4sc3n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G22 compound treatment 729281.0 123000.0 0.55 664438.0 96700.0 0.48 0.7281 0.9976 1974167 ChemDiv1_008602 CCOc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)ccc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G23 mock treatment 712952.0 107000.0 0.48 674320.0 107000.0 0.53 0.711 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 G24 mock treatment 563485.0 -42700.0 -0.19 536707.0 -31100.0 -0.15 -0.2441 -0.9942 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H01 compound treatment 702447.0 96200.0 0.43 637588.0 69800.0 0.35 0.5491 0.9941 1974168 ChemDiv1_008603 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(cc3)N(CC)CC)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H02 compound treatment 655830.0 49600.0 0.22 627503.0 59700.0 0.3 0.3662 0.99 1974169 ChemDiv1_008604 Cc1nc(SC2CCCCC2=O)c(C#N)c(c3cccs3)c1C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H03 compound treatment 915501.0 309000.0 1.38 950252.0 382000.0 1.89 2.3187 0.9881 1137375 ChemDiv1_008605 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)c(OC)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H04 compound treatment 689529.0 83300.0 0.37 664219.0 96500.0 0.48 0.6015 0.9925 1974170 ChemDiv1_008606 O=C(Oc1ccc(/C=C/2\S/C(=N\c3ccc4OCOc4c3)/N(C2=O)c5ccc6OCOc6c5)cc1)N7CCOCC7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H05 compound treatment 799021.0 193000.0 0.86 748849.0 181000.0 0.9 1.2445 0.9998 1714964 ChemDiv1_008607 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OCC)c(OCC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H06 compound treatment 711218.0 105000.0 0.47 679860.0 112000.0 0.56 0.7249 0.9966 1974171 ChemDiv1_008608 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(OC)c(OC)cc3Cl)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H07 compound treatment 734025.0 128000.0 0.57 691873.0 124000.0 0.61 0.8392 0.9994 1372725 ChemDiv1_008609 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4cc(OC)ccc4OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H08 compound treatment 744607.0 138000.0 0.62 687201.0 119000.0 0.59 0.8563 0.9997 1974172 ChemDiv1_008610 CCCOc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)OCCSCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H09 compound treatment 741762.0 136000.0 0.61 714743.0 147000.0 0.73 0.9438 0.9959 1974173 ChemDiv1_008611 CC1CCCN(C1)c2cc(Nc3ccc(C)cc3C)c([N+](=O)[O-])c4nonc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H10 compound treatment 737014.0 131000.0 0.59 705461.0 138000.0 0.68 0.8963 0.9971 1974174 ChemDiv1_008612 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Cl)C(=O)CC(C2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H11 compound treatment 756298.0 150000.0 0.67 699265.0 131000.0 0.65 0.9356 0.9999 1974175 ChemDiv1_008613 [O-][N+](=O)c1c(NCc2ccccc2)cc(N3CCOCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H12 compound treatment 706976.0 101000.0 0.45 699173.0 131000.0 0.65 0.7792 0.9839 1974176 ChemDiv1_008614 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H13 compound treatment 761720.0 155000.0 0.7 706039.0 138000.0 0.68 0.9765 1.0 1130318 ChemDiv1_008615 COc1ccc(cc1OC)c2nc3c4c5CCCCCc5sc4ncn3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H14 compound treatment 739217.0 133000.0 0.6 697506.0 130000.0 0.64 0.8754 0.9993 1974177 ChemDiv1_008616 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H15 compound treatment 741871.0 136000.0 0.61 710417.0 143000.0 0.71 0.929 0.9971 1974178 ChemDiv1_008617 O=C(CCN1C(=O)c2ccccc2C1=O)NCCCn3ccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H16 compound treatment 728103.0 122000.0 0.55 684253.0 116000.0 0.58 0.7938 0.9996 1974179 ChemDiv1_008618 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H17 compound treatment 744153.0 138000.0 0.62 686913.0 119000.0 0.59 0.8539 0.9997 1974180 ChemDiv1_008619 COc1ccc(cc1)C2=NN3COc4ccc(Br)cc4C3C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H18 compound treatment 694458.0 88200.0 0.39 667384.0 99600.0 0.49 0.6282 0.9939 1402297 ChemDiv1_008620 O=C(N1CCN(Cc2ccc3OCOc3c2)CC1)c4cc(nc5ccccc45)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H19 compound treatment 724827.0 119000.0 0.53 701109.0 133000.0 0.66 0.8425 0.9941 1584494 ChemDiv1_008621 COc1ccccc1NC(=O)c2c(C)nc3sc(C(=O)N)c(N)c3c2c4ccc(C)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H20 compound treatment 718705.0 112000.0 0.5 638803.0 71000.0 0.35 0.6048 0.9847 1515443 ChemDiv1_008622 CCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H21 compound treatment 706707.0 100000.0 0.45 676177.0 108000.0 0.54 0.6978 0.9961 1974181 ChemDiv1_008623 CC(=O)c1cc(C#N)c(SCCCCSc2nc(C)c(cc2C#N)C(=O)C)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H22 compound treatment 704061.0 97800.0 0.44 632891.0 65100.0 0.32 0.5378 0.9887 1699522 ChemDiv1_008624 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(N4CCOCC4)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H23 mock treatment 684131.0 77900.0 0.35 636574.0 68800.0 0.34 0.4876 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 H24 mock treatment 513351.0 -92900.0 -0.42 539401.0 -28400.0 -0.14 -0.3934 -0.8963 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I01 compound treatment 635814.0 29600.0 0.13 606406.0 38600.0 0.19 0.229 0.9838 1974182 ChemDiv1_008625 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccc5C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I02 compound treatment 684160.0 77900.0 0.35 615281.0 47500.0 0.24 0.4131 0.9817 1974183 ChemDiv1_008626 COC(=O)c1cc(cc(c1)n2c(C)cc(C(=O)CSc3nnc4cc(C)c5ccccc5n34)c2C)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I03 compound treatment 715856.0 110000.0 0.49 671644.0 104000.0 0.51 0.7108 0.9997 1245633 ChemDiv1_008627 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5cccc(F)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I04 compound treatment 738950.0 133000.0 0.59 665363.0 97600.0 0.48 0.7619 0.9948 1974184 ChemDiv1_008628 Cc1nc(SCC(=O)Nc2ccc3OCCOc3c2)c4c5CCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I05 compound treatment 738447.0 132000.0 0.59 681854.0 114000.0 0.57 0.8181 0.9997 1974185 ChemDiv1_008629 OC(=O)CSc1nnc([nH]1)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I06 compound treatment 711979.0 106000.0 0.47 689047.0 121000.0 0.6 0.7595 0.993 1682381 ChemDiv1_008630 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(Cl)cc3)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I07 compound treatment 752435.0 146000.0 0.65 748345.0 181000.0 0.89 1.0953 0.9882 1974186 ChemDiv1_008631 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)c(Br)cc1OCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I08 compound treatment 765802.0 160000.0 0.71 680791.0 113000.0 0.56 0.901 0.9927 1599258 ChemDiv1_008632 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I09 compound treatment 768405.0 162000.0 0.73 713005.0 145000.0 0.72 1.0221 1.0 1974187 ChemDiv1_008633 COC(=O)COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I10 compound treatment 728235.0 122000.0 0.55 702109.0 134000.0 0.67 0.8567 0.9952 1974188 ChemDiv1_008634 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(c3)[N+](=O)[O-])S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I11 compound treatment 759406.0 153000.0 0.69 707043.0 139000.0 0.69 0.9727 1.0 1690814 ChemDiv1_008635 Clc1ccc(cc1)C2C3=C(Nc4ncnn24)c5ccccc5CCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I12 compound treatment 734249.0 128000.0 0.57 721747.0 154000.0 0.76 0.9446 0.9901 1443897 ChemDiv1_008636 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccs3)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I13 compound treatment 778342.0 172000.0 0.77 715995.0 148000.0 0.73 1.064 0.9997 1974189 ChemDiv1_008637 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4ccc(C)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I14 compound treatment 762027.0 156000.0 0.7 721067.0 153000.0 0.76 1.0301 0.9991 1389162 ChemDiv1_008638 OC(=O)CCCC(=O)N1N=C(CC1c2cn(nc2c3ccccc3)c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I15 compound treatment 736873.0 131000.0 0.58 740879.0 173000.0 0.86 1.0199 0.9826 1787324 ChemDiv1_008639 OC(=O)CCC(=O)N1C(C2=C(CC(CC2=O)c3ccc(F)cc3)Nc4ccccc14)c5ccc(o5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I16 compound treatment 776183.0 170000.0 0.76 691973.0 124000.0 0.62 0.973 0.9945 1620168 ChemDiv1_008640 Fc1ccc(cc1)C2CC(=NN2C(=O)c3cccnc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I17 compound treatment 729800.0 124000.0 0.55 720147.0 152000.0 0.75 0.9249 0.9883 1690452 ChemDiv1_008641 Cc1nc(Nc2ccc(cc2)S(=O)(=O)N)nc(Nc3ccc(cc3)S(=O)(=O)N)c1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I18 compound treatment 742209.0 136000.0 0.61 681353.0 114000.0 0.56 0.8283 0.9992 1974190 ChemDiv1_008642 CCCCOc1ccc(cc1)C2Oc3ccc(OC)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I19 compound treatment 725661.0 119000.0 0.53 676903.0 109000.0 0.54 0.7603 1.0 1944230 ChemDiv1_008643 CCOc1ccc(CC2S/C(=N/c3ccc(cc3)C(=O)O)/N(CC=C)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I20 compound treatment 730159.0 124000.0 0.55 670194.0 102000.0 0.51 0.751 0.999 1667484 ChemDiv1_008644 COc1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I21 compound treatment 738227.0 132000.0 0.59 676352.0 109000.0 0.54 0.7981 0.9989 1974191 ChemDiv1_008645 COC(=O)c1sc(NC(=O)CSc2ncnc3sc(C)c(C)c23)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I22 compound treatment 745603.0 139000.0 0.62 669365.0 102000.0 0.5 0.797 0.9943 1974192 ChemDiv1_008646 COc1ccc(OC)c(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccc(Br)c(C)c3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I23 mock treatment 739613.0 133000.0 0.6 679463.0 112000.0 0.55 0.8134 0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 I24 mock treatment 558346.0 -47900.0 -0.21 301325.0 -266000.0 -1.32 -1.0849 -0.8113 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J01 compound treatment 618726.0 12500.0 0.06 566233.0 -1540.0 -0.01 0.0342 0.6053 1974193 ChemDiv1_008647 CCOc1cccc(c1)N2C(=O)/C(=C\c3ccc(o3)c4cccc(c4)[N+](=O)[O-])/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J02 compound treatment 656213.0 50000.0 0.22 604499.0 36700.0 0.18 0.2869 0.9947 1974194 ChemDiv1_008648 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc3cccnc23)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J03 compound treatment 714552.0 108000.0 0.48 635873.0 68100.0 0.34 0.5814 0.9843 1297893 ChemDiv1_008649 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(NC(=O)C)cc3)c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J04 compound treatment 682762.0 76500.0 0.34 647872.0 80100.0 0.4 0.5228 0.9973 1393149 ChemDiv1_008650 Cc1cc2nc3sc(=Cc4ccc(OC(=O)N5CCOCC5)cc4)c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J05 compound treatment 1914797.0 1310000.0 5.86 2406793.0 1840000.0 9.11 10.5838 0.9772 1251601 ChemDiv1_008651 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)c(OC)c3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J06 compound treatment 723072.0 117000.0 0.52 662058.0 94300.0 0.47 0.7001 0.9984 1974195 ChemDiv1_008652 COc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(OCC(=O)O)c(OC)c3)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J07 compound treatment 703558.0 97300.0 0.44 696805.0 129000.0 0.64 0.7601 0.9825 1974196 ChemDiv1_008653 COc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccccc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J08 compound treatment 715878.0 110000.0 0.49 680887.0 113000.0 0.56 0.7433 0.9978 1974197 ChemDiv1_008654 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J09 compound treatment 731416.0 125000.0 0.56 680801.0 113000.0 0.56 0.7922 1.0 1974198 ChemDiv1_008655 CC1CCCN(C1)c2cc(Nc3ccc(C)c(C)c3)c([N+](=O)[O-])c4nonc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J10 compound treatment 721542.0 115000.0 0.52 665327.0 97600.0 0.48 0.7067 0.9995 1974199 ChemDiv1_008656 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J11 compound treatment 740504.0 134000.0 0.6 656633.0 88900.0 0.44 0.7363 0.9883 1974200 ChemDiv1_008657 Cc1ccccc1Nc2cc(N3CCCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J12 compound treatment 727565.0 121000.0 0.54 677559.0 110000.0 0.54 0.7686 1.0 1974201 ChemDiv1_008658 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)c(OCC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J13 compound treatment 745995.0 140000.0 0.63 705049.0 137000.0 0.68 0.9233 0.9991 1643674 ChemDiv1_008659 C(Sc1nc2ccccc2o1)c3nc4c5c6CCCCCc6sc5ncn4n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J14 compound treatment 740402.0 134000.0 0.6 648168.0 80400.0 0.4 0.7063 0.9801 1974202 ChemDiv1_008660 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J15 compound treatment 784169.0 178000.0 0.8 701379.0 134000.0 0.66 1.0312 0.9958 1656095 ChemDiv1_008661 Brc1ccc(NC(=O)CCN2C(=O)c3ccccc3C2=O)nc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J16 compound treatment 744177.0 138000.0 0.62 682177.0 114000.0 0.57 0.8374 0.9991 1974203 ChemDiv1_008662 CCOCCOC(=O)C1=C(C)NC(=O)NC1c2cccc(OCc3ccccc3)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J17 compound treatment 798829.0 193000.0 0.86 730441.0 163000.0 0.81 1.1794 0.9994 1490647 ChemDiv1_008663 Brc1ccc2OC3(CCCC3)N4N=C(CC4c2c1)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J18 compound treatment 737780.0 132000.0 0.59 679606.0 112000.0 0.55 0.8081 0.9995 1400777 ChemDiv1_008664 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3nc4ccc(cc4s3)S(=O)(=O)C)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J19 compound treatment 714404.0 108000.0 0.48 684578.0 117000.0 0.58 0.7516 0.9961 1974204 ChemDiv1_008665 CCOC(=O)c1cc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)C)nc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J20 compound treatment 713960.0 108000.0 0.48 654428.0 86700.0 0.43 0.6445 0.9983 1485192 ChemDiv1_008666 CCCCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J21 compound treatment 731061.0 125000.0 0.56 650559.0 82800.0 0.41 0.6851 0.9884 1974205 ChemDiv1_008667 CC(=O)c1cc(C#N)c(SCC(=O)c2cc3ccccc3oc2=O)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J22 compound treatment 733211.0 127000.0 0.57 623629.0 55900.0 0.28 0.5976 0.9453 1382070 ChemDiv1_008668 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(NCc4ccccc4)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J23 mock treatment 704472.0 98200.0 0.44 648777.0 81000.0 0.4 0.5947 0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 J24 mock treatment 526899.0 -79300.0 -0.36 511896.0 -55900.0 -0.28 -0.4468 -0.9924 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K01 compound treatment 638385.0 32200.0 0.14 592399.0 24600.0 0.12 0.188 0.9966 1974206 ChemDiv1_008669 CSc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(c5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K02 compound treatment 680278.0 74000.0 0.33 610245.0 42500.0 0.21 0.3832 0.976 1974207 ChemDiv1_008670 Clc1ccc(cc1)c2csc3ncnc(NCCCN4CCOCC4)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K03 compound treatment 698773.0 92500.0 0.41 664850.0 97100.0 0.48 0.633 0.9972 1974208 ChemDiv1_008671 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5ccccc5C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K04 compound treatment 698778.0 92500.0 0.41 659451.0 91700.0 0.45 0.6141 0.9989 1974209 ChemDiv1_008672 Fc1ccccc1NC(=O)CSc2nnc3sc4ccccc4n23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K05 compound treatment 720443.0 114000.0 0.51 674193.0 106000.0 0.53 0.7343 0.9999 1974210 ChemDiv1_008673 OC(=O)CSc1ncn(n1)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K06 compound treatment 716292.0 110000.0 0.49 667047.0 99300.0 0.49 0.6961 1.0 1173097 ChemDiv1_008674 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K07 compound treatment 746329.0 140000.0 0.63 702672.0 135000.0 0.67 0.916 0.9995 1974211 ChemDiv1_008675 COc1cc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K08 compound treatment 770806.0 165000.0 0.74 709790.0 142000.0 0.7 1.0184 0.9997 1404508 ChemDiv1_008676 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K09 compound treatment 754394.0 148000.0 0.66 711093.0 143000.0 0.71 0.971 0.9994 1974212 ChemDiv1_008677 Cc1cc(/C=C/2\SC(=O)N(Cc3ccc(Cl)cc3)C2=O)c(C)n1c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K10 compound treatment 758433.0 152000.0 0.68 700544.0 133000.0 0.66 0.9468 0.9998 1974213 ChemDiv1_008678 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K11 compound treatment 747816.0 142000.0 0.63 729700.0 162000.0 0.8 1.0154 0.9932 1974214 ChemDiv1_008679 ClC1=CCC2C(C1)C(=O)N(CCCCCCN3C(=O)C4CC=C(Cl)CC4C3=O)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K12 compound treatment 702115.0 95900.0 0.43 677650.0 110000.0 0.54 0.6884 0.9931 1510679 ChemDiv1_008680 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K13 compound treatment 774700.0 168000.0 0.75 697853.0 130000.0 0.64 0.9889 0.9969 1787330 ChemDiv1_008681 COc1cccc(c1)C2N(C(=O)C3CC3)c4ccccc4NC5=C2C(=O)CC(C5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K14 compound treatment 762963.0 157000.0 0.7 709717.0 142000.0 0.7 0.9933 1.0 1736666 ChemDiv1_008682 Cc1ccc(cc1)c2nn(cc2C3CC(=NN3C(=O)CCCC(=O)O)c4cccs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K15 compound treatment 827567.0 221000.0 0.99 766185.0 198000.0 0.98 1.3956 1.0 1974215 ChemDiv1_008683 O=C1CCCN1CCCN/C=C\2/C(=O)N(N=C2c3ccccc3)c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K16 compound treatment 748159.0 142000.0 0.64 694558.0 127000.0 0.63 0.8934 1.0 1682550 ChemDiv1_008684 Cc1ccc(cc1)C2=NN(C(C2)c3ccccc3F)C(=O)c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K17 compound treatment 762430.0 156000.0 0.7 688025.0 120000.0 0.6 0.9156 0.9968 1390449 ChemDiv1_008685 COc1ccc2[nH]c3C(CC(C)CCC=C(C)C)NCCc3c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K18 compound treatment 745229.0 139000.0 0.62 635538.0 67800.0 0.34 0.6773 0.9581 1974216 ChemDiv1_008686 CCCCCCOc1ccc(cc1)C2Oc3ccc(OC)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K19 compound treatment 770000.0 164000.0 0.73 672440.0 105000.0 0.52 0.885 0.9856 1974217 ChemDiv1_008687 O=C(CSc1nnc2sc3ccccc3n12)c4cccc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K20 compound treatment 762461.0 156000.0 0.7 652379.0 84600.0 0.42 0.7909 0.97 1974218 ChemDiv1_008688 N#CC1(CCc2c(C1)sc3ncnc(N4CCOCC4)c23)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K21 compound treatment 744377.0 138000.0 0.62 655727.0 88000.0 0.44 0.7454 0.9853 1974219 ChemDiv1_008689 Cc1cc2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K22 compound treatment 721208.0 115000.0 0.51 661858.0 94100.0 0.47 0.6935 0.9988 1974220 ChemDiv1_008690 Brc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K23 mock treatment 722482.0 116000.0 0.52 647767.0 80000.0 0.4 0.6482 0.991 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 K24 mock treatment 524154.0 -82100.0 -0.37 503134.0 -64600.0 -0.32 -0.4862 -0.9976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L01 compound treatment 613111.0 6880.0 0.03 566536.0 -1230.0 -0.01 0.0175 0.556 1974221 ChemDiv1_008691 CCOc1cccc(c1)N2C(=O)/C(=C\c3c(C)nn(c3O)c4ccccc4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L02 compound treatment 690931.0 84700.0 0.38 648739.0 81000.0 0.4 0.5517 0.9996 1974222 ChemDiv1_008692 Nc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L03 compound treatment 724936.0 119000.0 0.53 660621.0 92900.0 0.46 0.701 0.9974 1191496 ChemDiv1_008693 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)c(O)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L04 compound treatment 696222.0 90000.0 0.4 629073.0 61300.0 0.3 0.4996 0.9903 1307524 ChemDiv1_008694 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Cl)c1OCc5cccc(c5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L05 compound treatment 735391.0 129000.0 0.58 637676.0 69900.0 0.35 0.6537 0.97 1165808 ChemDiv1_008695 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L06 compound treatment 676837.0 70600.0 0.32 641662.0 73900.0 0.37 0.4823 0.9973 1974223 ChemDiv1_008696 COc1ccc(cc1)N2C(=O)/C(=C/c3cc4OCOc4cc3Cl)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L07 compound treatment 723305.0 117000.0 0.52 658196.0 90400.0 0.45 0.6873 0.9969 1974224 ChemDiv1_008697 Cc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccccc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L08 compound treatment 706246.0 100000.0 0.45 657545.0 89800.0 0.44 0.631 1.0 1231680 ChemDiv1_008698 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4cc5OCOc5cc4Br)C(=O)CC(C)(C)C3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L09 compound treatment 720304.0 114000.0 0.51 656762.0 89000.0 0.44 0.6728 0.9973 1974225 ChemDiv1_008699 [O-][N+](=O)c1c(Nc2ccccc2Cl)cc(N3CCOCC3)c4nonc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L10 compound treatment 732888.0 127000.0 0.57 658160.0 90400.0 0.45 0.7175 0.9932 1974226 ChemDiv1_008700 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L11 compound treatment 713918.0 108000.0 0.48 674764.0 107000.0 0.53 0.7156 0.9989 1786639 ChemDiv1_008701 OC(=O)c1n[nH]c(=O)c2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L12 compound treatment 719744.0 114000.0 0.51 665740.0 98000.0 0.49 0.7025 0.9997 1974227 ChemDiv1_008702 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L13 compound treatment 736215.0 130000.0 0.58 642068.0 74300.0 0.37 0.6717 0.9756 1368267 ChemDiv1_008703 COc1ccc(Cc2nc3c4c5CCCCCc5sc4ncn3n2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L14 compound treatment 725405.0 119000.0 0.53 648996.0 81200.0 0.4 0.6617 0.9903 1974228 ChemDiv1_008704 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L15 compound treatment 767911.0 162000.0 0.72 689998.0 122000.0 0.61 0.9399 0.9961 1666167 ChemDiv1_008705 Cn1c(=O)n(C)c2nc(S)n(CC3CC3)c2c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L16 compound treatment 727801.0 122000.0 0.54 658915.0 91100.0 0.45 0.7041 0.9957 1974229 ChemDiv1_008706 COCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(O)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L17 compound treatment 797134.0 191000.0 0.85 715665.0 148000.0 0.73 1.1223 0.9971 1974230 ChemDiv1_008707 Clc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L18 compound treatment 698657.0 92400.0 0.41 647489.0 79700.0 0.39 0.5718 0.9997 1974231 ChemDiv1_008708 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2cnc(NC(=O)/C=C/c3ccc4OCOc4c3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L19 compound treatment 731277.0 125000.0 0.56 659988.0 92200.0 0.46 0.7188 0.9949 1138097 ChemDiv1_008709 CCOc1ccc(cc1)C(=O)c2sc3nc(N)c(C#N)c(CC)c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L20 compound treatment 731626.0 125000.0 0.56 631858.0 64100.0 0.32 0.6214 0.9636 1712663 ChemDiv1_008710 C=CCn1c(NC(=O)C2CCCCC2)nc3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L21 compound treatment 747058.0 141000.0 0.63 644995.0 77200.0 0.38 0.7163 0.9714 1974232 ChemDiv1_008711 Nc1nc(SCC(=O)c2ccccc2)c(C#N)c(c1C#N)c3ccc(O)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L22 compound treatment 699985.0 93800.0 0.42 627258.0 59500.0 0.29 0.5051 0.985 1320992 ChemDiv1_008712 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(NCc4nc5ccccc5[nH]4)c6ccccc36 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L23 mock treatment 730115.0 124000.0 0.55 621873.0 54100.0 0.27 0.5816 0.9444 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 L24 mock treatment 517510.0 -88700.0 -0.4 528408.0 -39400.0 -0.19 -0.4187 -0.9464 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M01 compound treatment 679894.0 73700.0 0.33 653701.0 85900.0 0.43 0.5342 0.992 1852718 ChemDiv1_008713 CN(C)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(F)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M02 compound treatment 668531.0 62300.0 0.28 609667.0 41900.0 0.21 0.344 0.9894 1974233 ChemDiv1_008714 FC(F)(F)c1cccc(Oc2nnc(c3ccccc3)c4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M03 compound treatment 725018.0 119000.0 0.53 647523.0 79800.0 0.4 0.6554 0.9893 1974234 ChemDiv1_008715 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4cccnc4)C(=O)Nc5cccc(c5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M04 compound treatment 704750.0 98500.0 0.44 627184.0 59400.0 0.29 0.52 0.9807 1974235 ChemDiv1_008716 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc3sc4ccccc4n23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M05 compound treatment 730164.0 124000.0 0.55 654157.0 86400.0 0.43 0.6949 0.9918 1914555 ChemDiv1_008717 OC(=O)CSc1nncn1c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M06 compound treatment 691967.0 85700.0 0.38 646777.0 79000.0 0.39 0.5481 1.0 1280312 ChemDiv1_008718 COc1ccc(cc1OC)C2CC(=NN2C(=O)CCC(=O)O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M07 compound treatment 2129162.0 1520000.0 6.82 2061645.0 1490000.0 7.4 10.0533 0.9992 1974236 ChemDiv1_008719 Oc1ccc(Br)cc1/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M08 compound treatment 725684.0 119000.0 0.53 661468.0 93700.0 0.46 0.7063 0.9975 1225381 ChemDiv1_008720 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M09 compound treatment 708919.0 103000.0 0.46 656637.0 88900.0 0.44 0.6363 0.9998 1974237 ChemDiv1_008721 COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M10 compound treatment 774270.0 168000.0 0.75 712942.0 145000.0 0.72 1.0404 0.9997 1974238 ChemDiv1_008722 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M11 compound treatment 730967.0 125000.0 0.56 691962.0 124000.0 0.62 0.8298 0.9988 1974239 ChemDiv1_008723 CCCCC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)N4CCN(CC4)C(=O)C(CCCC)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M12 compound treatment 718667.0 112000.0 0.5 672103.0 104000.0 0.52 0.7214 0.9999 1414122 ChemDiv1_008724 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)C(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M13 compound treatment 745499.0 139000.0 0.62 674112.0 106000.0 0.53 0.8133 0.9965 1442334 ChemDiv1_008725 OC(=O)CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccnc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M14 compound treatment 728829.0 123000.0 0.55 659532.0 91800.0 0.45 0.7095 0.9956 1350222 ChemDiv1_008726 COc1ccc(cc1)C2CC(=NN2C(=O)c3cccnc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M15 compound treatment 739692.0 133000.0 0.6 675954.0 108000.0 0.54 0.8014 0.9985 1974240 ChemDiv1_008727 Clc1ccc(NC(=O)CSc2nnc(c3cccs3)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M16 compound treatment 710197.0 104000.0 0.47 663163.0 95400.0 0.47 0.6632 1.0 1974241 ChemDiv1_008728 COc1ccccc1C2CC(=NN2C(=O)c3cccnc3)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M17 compound treatment 817227.0 211000.0 0.94 734567.0 167000.0 0.83 1.2521 0.9978 1974242 ChemDiv1_008729 CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5ccc(OC)cc45)[C@H]3C[C@@H]2[C@@H]1OC(=O)C)OC(=O)c6cc(OC)c(OC)c(OC)c6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M18 compound treatment 716926.0 111000.0 0.5 663474.0 95700.0 0.47 0.6856 0.9998 1379242 ChemDiv1_008730 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M19 compound treatment 710888.0 105000.0 0.47 659267.0 91500.0 0.45 0.6518 0.9999 1134977 ChemDiv1_008731 Cc1cc2nnc(SCC(=O)c3ccc4OCOc4c3)n2c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M20 compound treatment 675013.0 68800.0 0.31 607112.0 39300.0 0.19 0.3555 0.9757 1974243 ChemDiv1_008732 Cc1cc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)c(C)n1c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M21 compound treatment 748612.0 142000.0 0.64 658232.0 90500.0 0.45 0.7675 0.9851 1525329 ChemDiv1_008733 COc1ccc(cc1OC)C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M22 compound treatment 721461.0 115000.0 0.52 618833.0 51100.0 0.25 0.5436 0.9462 1974244 ChemDiv1_008734 COc1ccc(cc1)N2C(=O)/C(=C\c3cc(Br)ccc3O)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M23 mock treatment 709180.0 103000.0 0.46 644031.0 76300.0 0.38 0.593 0.9951 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 M24 mock treatment 574617.0 -31600.0 -0.14 426166.0 -142000.0 -0.7 -0.5961 -0.833 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N01 compound treatment 637133.0 30900.0 0.14 583873.0 16100.0 0.08 0.1542 0.9658 1974245 ChemDiv1_008735 Cc1cc(/C=C/2\NC(=S)NC2=O)c(C)n1c3ccc(I)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N02 compound treatment 664195.0 58000.0 0.26 563005.0 -4760.0 -0.02 0.1668 0.6402 1492010 ChemDiv1_008736 Cc1nc2sc(C(=O)c3ccccc3)c(N)c2c(c4ccncc4)c1C(=O)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N03 compound treatment 706355.0 100000.0 0.45 642153.0 74400.0 0.37 0.5775 0.9953 1173169 ChemDiv1_008737 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC(=O)C)c3)c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N04 compound treatment 836159.0 230000.0 1.03 724141.0 156000.0 0.77 1.2755 0.9902 1724522 ChemDiv1_008738 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N05 compound treatment 1146495.0 540000.0 2.42 1058091.0 490000.0 2.43 3.4276 1.0 1493768 ChemDiv1_008739 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N06 compound treatment 682028.0 75800.0 0.34 597224.0 29500.0 0.15 0.3431 0.9289 1974246 ChemDiv1_008740 CCOc1cc(/C=C/2\NC(=S)N(C2=O)c3ccc(OC)cc3)ccc1OCc4cccc(F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N07 compound treatment 703113.0 96900.0 0.43 639387.0 71600.0 0.35 0.5575 0.995 1974247 ChemDiv1_008741 Cc1nc(NC2=NC(CC(=O)N2)C(=O)Nc3ccc(Cl)cc3)nc4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N08 compound treatment 661536.0 55300.0 0.25 621532.0 53800.0 0.27 0.3634 0.9993 1369963 ChemDiv1_008742 CCCOc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N09 compound treatment 717443.0 111000.0 0.5 655206.0 87400.0 0.43 0.6583 0.9976 1974248 ChemDiv1_008743 Cc1ccc(C)c(Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N10 compound treatment 678746.0 72500.0 0.32 642244.0 74500.0 0.37 0.4904 0.998 1974249 ChemDiv1_008744 CCOc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)cc4)C(=O)OCCSCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N11 compound treatment 719997.0 114000.0 0.51 648620.0 80900.0 0.4 0.6433 0.9929 1974250 ChemDiv1_008745 Cc1cc(C)n2c(SCC(=O)O)nnc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N12 compound treatment 695940.0 89700.0 0.4 629480.0 61700.0 0.31 0.5001 0.9909 1974251 ChemDiv1_008746 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CC(C2)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N13 compound treatment 720249.0 114000.0 0.51 653900.0 86100.0 0.43 0.6626 0.996 1974252 ChemDiv1_008747 COc1ccc(cc1)c2oc3ncn4nc(CSc5nc6ccccc6o5)nc4c3c2c7ccc(OC)cc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N14 compound treatment 707142.0 101000.0 0.45 633169.0 65400.0 0.32 0.5485 0.9867 1974253 ChemDiv1_008748 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N15 compound treatment 789604.0 183000.0 0.82 674273.0 107000.0 0.53 0.9535 0.9772 1974254 ChemDiv1_008749 CCOc1ccc(/N=C\2/S\C(=C/c3ccc(cc3)N(C)C)\C(=O)N2CC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N16 compound treatment 713633.0 107000.0 0.48 624905.0 57100.0 0.28 0.5401 0.9681 1598175 ChemDiv1_008750 CCOc1ccc(cc1)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N17 compound treatment 739290.0 133000.0 0.6 654139.0 86400.0 0.43 0.7237 0.9868 1281223 ChemDiv1_008751 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N18 compound treatment 754872.0 149000.0 0.67 646326.0 78600.0 0.39 0.7457 0.9674 1974255 ChemDiv1_008752 CCOC(=O)c1sc(NC(=O)CSC2=NCCS2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N19 compound treatment 747532.0 141000.0 0.63 636079.0 68300.0 0.34 0.6865 0.9571 1325983 ChemDiv1_008753 CCCSC1=C(C#N)C(C(=C(N1)c2ccccc2)C(=O)OCC)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N20 compound treatment 704282.0 98000.0 0.44 626138.0 58400.0 0.29 0.5148 0.9795 1152874 ChemDiv1_008754 O=C(Nc1nc2ccccc2n1Cc3ccccc3)C4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N21 compound treatment 702559.0 96300.0 0.43 628680.0 60900.0 0.3 0.5183 0.9848 1974256 ChemDiv1_008755 Nc1nc(SCC(=O)Nc2ccccc2)c(C#N)c(c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N22 compound treatment 716415.0 110000.0 0.49 608863.0 41100.0 0.2 0.4927 0.9234 1974257 ChemDiv1_008756 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nnc(SCC(=O)Nc4ccccc4)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N23 mock treatment 723891.0 118000.0 0.53 608076.0 40300.0 0.2 0.5136 0.9119 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 N24 mock treatment 586771.0 -19500.0 -0.09 376910.0 -191000.0 -0.95 -0.7302 -0.769 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O01 compound treatment 620544.0 14300.0 0.06 571228.0 3460.0 0.02 0.0574 0.8658 1974258 ChemDiv1_008757 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5cccc(c5)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O02 compound treatment 635362.0 29100.0 0.13 555961.0 -11800.0 -0.06 0.0508 0.3557 1974259 ChemDiv1_008758 COc1ccc(cc1)c2csc3nc(SCC(=O)Nc4ccc5OCCOc5c4)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O03 compound treatment 654784.0 48600.0 0.22 628246.0 60500.0 0.3 0.3655 0.9876 1597134 ChemDiv1_008759 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc(s3)C(C)(C)C)C(=O)Nc4cccc(F)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O04 compound treatment 660327.0 54100.0 0.24 592850.0 25100.0 0.12 0.2591 0.9519 1974260 ChemDiv1_008760 CCOC(=O)c1c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)sc5CCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O05 compound treatment 687731.0 81500.0 0.36 620010.0 52200.0 0.26 0.441 0.9859 1480676 ChemDiv1_008761 COc1ccc(cc1)N(CC(=O)Nc2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O06 compound treatment 678383.0 72100.0 0.32 613536.0 45800.0 0.23 0.3887 0.985 1436325 ChemDiv1_008762 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3Cl)C(=O)CCCC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O07 compound treatment 690813.0 84600.0 0.38 629776.0 62000.0 0.31 0.4849 0.9946 1974261 ChemDiv1_008763 CCOC(=O)COc1ccc(/C=C/2\SC(=O)N(Cc3ccc(F)cc3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O08 compound treatment 697001.0 90800.0 0.41 617293.0 49500.0 0.25 0.4608 0.9708 1616202 ChemDiv1_008764 COc1ccc(cc1OC)C2=NN(C(C2)c3ccccc3F)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O09 compound treatment 689263.0 83000.0 0.37 611922.0 44200.0 0.22 0.4175 0.968 1974262 ChemDiv1_008765 COC(=O)c1ccc(/C=C/2\SC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O10 compound treatment 687476.0 81200.0 0.36 629693.0 61900.0 0.31 0.4741 0.9964 1974263 ChemDiv1_008766 COc1ccc(cc1OC)C2=NN(C(C2)c3ccc(C)cc3)C(=O)c4ccc(Br)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O11 compound treatment 655967.0 49700.0 0.22 623323.0 55600.0 0.28 0.352 0.9945 1663346 ChemDiv1_008767 Clc1ccccc1NC(=O)C2COc3ccccc3O2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O12 compound treatment 685697.0 79500.0 0.36 599417.0 31600.0 0.16 0.3624 0.9322 1361217 ChemDiv1_008768 COc1ccc(cc1OC)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O13 compound treatment 690877.0 84600.0 0.38 629090.0 61300.0 0.3 0.4827 0.994 1974264 ChemDiv1_008769 FC(F)(F)C(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O14 compound treatment 694303.0 88100.0 0.39 612022.0 44300.0 0.22 0.4338 0.9616 1216653 ChemDiv1_008770 COc1cccc(C2CC(=NN2C(=O)c3ccncc3)c4ccc(Br)cc4)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O15 compound treatment 729899.0 124000.0 0.55 600331.0 32600.0 0.16 0.5055 0.8767 1043054 ChemDiv1_008771 Cc1cc2nc(SCC(=O)O)[nH]c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O16 compound treatment 704807.0 98600.0 0.44 613681.0 45900.0 0.23 0.4728 0.9525 1167123 ChemDiv1_008772 COc1ccc(C2CC(=NN2S(=O)(=O)c3ccccc3)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O17 compound treatment 717400.0 111000.0 0.5 641075.0 73300.0 0.36 0.6087 0.988 1635492 ChemDiv1_008773 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(C(=O)C)c2nc(C)cc(C)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O18 compound treatment 671868.0 65600.0 0.29 608947.0 41200.0 0.2 0.352 0.9841 1127058 ChemDiv1_008774 COc1ccc(cc1)C2=NN3C(C2)c4cc(OC)ccc4OC3c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O19 compound treatment 700753.0 94500.0 0.42 615945.0 48200.0 0.24 0.4679 0.9633 1974265 ChemDiv1_008775 O=C(CSc1ncnc2sc3CCCCc3c12)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O20 compound treatment 680330.0 74100.0 0.33 582886.0 15100.0 0.07 0.2875 0.8455 1974266 ChemDiv1_008776 Cc1cccc(c1)N2C(=O)NC(=O)/C(=C/c3cn(CC(=O)Nc4ccccc4)c5ccccc35)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O21 compound treatment 693111.0 86900.0 0.39 643031.0 75300.0 0.37 0.5386 0.9998 1974267 ChemDiv1_008777 Clc1ccccc1c2csc3[nH]c(=S)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O22 compound treatment 674296.0 68100.0 0.3 597790.0 30000.0 0.15 0.3206 0.9456 1974268 ChemDiv1_008778 COc1ccc(cc1)N2C(=O)/C(=C\c3ccc(Br)cc3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O23 mock treatment 679860.0 73600.0 0.33 601480.0 33700.0 0.17 0.3511 0.9504 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 O24 mock treatment 262643.0 -344000.0 -1.54 153892.0 -414000.0 -2.05 -2.5373 -0.99 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P01 compound treatment 607272.0 1040.0 0.0 550436.0 -17300.0 -0.09 -0.0574 -0.6679 1974269 ChemDiv1_008779 Cc1cc(/C=C/2\NC(=O)NC2=O)c(C)n1c3ccc(F)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P02 compound treatment 612726.0 6490.0 0.03 557787.0 -9980.0 -0.05 -0.0144 -0.2513 1137716 ChemDiv1_008780 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3cc4ccc(O)cc4oc3=O)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P03 compound treatment 645017.0 38800.0 0.17 584903.0 17100.0 0.08 0.1828 0.9458 1442438 ChemDiv1_008781 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3OC(=O)C)c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P04 compound treatment 636632.0 30400.0 0.14 589705.0 21900.0 0.11 0.1731 0.9938 1492385 ChemDiv1_008782 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc(OC)c(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P05 compound treatment 690576.0 84300.0 0.38 593485.0 25700.0 0.13 0.357 0.8961 1375246 ChemDiv1_008783 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC(=O)C)cc3)c(=O)n2C1c4ccc(OCC)c(OCC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P06 compound treatment 654108.0 47900.0 0.21 567430.0 -339.0 0.0 0.1503 0.7015 1974270 ChemDiv1_008784 COc1ccc(cc1)N2C(=O)/C(=C/c3ccc(OCC(=O)O)c(OC)c3)/NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P07 compound treatment 658232.0 52000.0 0.23 558171.0 -9600.0 -0.05 0.131 0.5513 1974271 ChemDiv1_008785 Cc1ccc2c(C)nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccc(Br)cc4)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P08 compound treatment 639553.0 33300.0 0.15 575120.0 7350.0 0.04 0.1312 0.8546 1974272 ChemDiv1_008786 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P09 compound treatment 652357.0 46100.0 0.21 563291.0 -4480.0 -0.02 0.1303 0.6275 1974273 ChemDiv1_008787 Oc1ccccc1Nc2cc(N3CCOCC3)c4nonc4c2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P10 compound treatment 648150.0 41900.0 0.19 561815.0 -5950.0 -0.03 0.1118 0.5887 1974274 ChemDiv1_008788 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P11 compound treatment 645069.0 38800.0 0.17 568546.0 777.0 0.0 0.1256 0.7226 1170150 ChemDiv1_008789 COc1ccc(cc1)S(=O)(=O)CCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P12 compound treatment 656950.0 50700.0 0.23 579156.0 11400.0 0.06 0.2004 0.8568 1974275 ChemDiv1_008790 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)cc3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P13 compound treatment 649193.0 43000.0 0.19 580854.0 13100.0 0.06 0.1818 0.8959 1692815 ChemDiv1_008791 CC(NC(=O)c1ccccc1NC(=O)c2ccccc2)C(=O)N3CCN(C)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P14 compound treatment 661591.0 55400.0 0.25 566502.0 -1270.0 -0.01 0.1708 0.689 1974276 ChemDiv1_008792 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P15 compound treatment 662203.0 56000.0 0.25 571238.0 3470.0 0.02 0.1893 0.7538 1669883 ChemDiv1_008793 COc1cc(C)nc(NC(=O)Nc2sc(NS(=O)(=O)c3ccccc3)nc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P16 compound treatment 668628.0 62400.0 0.28 576272.0 8500.0 0.04 0.2273 0.8047 1974277 ChemDiv1_008794 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)c(O)c(OC)c3)C(=O)CC(C2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P17 compound treatment 673054.0 66800.0 0.3 576974.0 9210.0 0.05 0.2437 0.8056 1385102 ChemDiv1_008795 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P18 compound treatment 669314.0 63100.0 0.28 608126.0 40400.0 0.2 0.341 0.9857 1974278 ChemDiv1_008796 CCOC(=O)c1sc(NC(=O)CSc2nc(c3ccco3)c(C#N)c(=O)[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P19 compound treatment 671770.0 65500.0 0.29 590752.0 23000.0 0.11 0.2879 0.915 1710821 ChemDiv1_008797 CCOC(=O)C1=C(NC(=C(C#N)C1c2cccnc2)SCC(=O)OC)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P20 compound treatment 627992.0 21800.0 0.1 579055.0 11300.0 0.06 0.1084 0.9653 1251902 ChemDiv1_008798 Cc1ccc(Cn2c(NC(=O)C3CCCCC3)nc4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P21 compound treatment 647455.0 41200.0 0.18 589496.0 21700.0 0.11 0.2066 0.9671 1974279 ChemDiv1_008799 Nc1nc(SCC(=O)c2ccc3ccccc3c2)c(C#N)c(c1C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P22 compound treatment 645734.0 39500.0 0.18 603010.0 35200.0 0.17 0.2485 1.0 1974280 ChemDiv1_008800 Cc1cc(C)nc(Sc2nnc(c3ccc(C)c(c3)S(=O)(=O)N4CCOCC4)c5ccccc25)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P23 mock treatment 644389.0 38200.0 0.17 566992.0 -777.0 0.0 0.1181 0.691 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.611 P24 mock treatment 471120.0 -135000.0 -0.6 190732.0 -377000.0 -1.87 -1.7484 -0.8906 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A01 compound treatment 598102.0 10700.0 0.05 580215.0 -11800.0 -0.06 -0.0074 -0.0983 1603828 ChemDiv1_008801 Cc1ccc(cc1S(=O)(=O)NCCO)c2nnc(Nc3cccc(Br)c3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A02 compound treatment 597742.0 10400.0 0.05 596984.0 4970.0 0.02 0.0502 0.9562 1974281 ChemDiv1_008802 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2nc(C)nc3sc4CCCCc4c23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A03 compound treatment 607406.0 20000.0 0.09 607892.0 15900.0 0.08 0.119 0.9979 1974282 ChemDiv1_008803 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(Br)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A04 compound treatment 612438.0 25000.0 0.11 611499.0 19500.0 0.1 0.1475 0.9972 1974283 ChemDiv1_008804 COC(=O)c1ccc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A05 compound treatment 619986.0 32600.0 0.15 623113.0 31100.0 0.15 0.2121 0.9996 1389103 ChemDiv1_008805 Cc1ccc(cc1S(=O)(=O)Nn2cnnc2)c3n[nH]c(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A06 compound treatment 653807.0 66400.0 0.3 653634.0 61600.0 0.31 0.4261 0.9999 1184895 ChemDiv1_008806 COc1ccc(OC)c(NC(=O)c2ccc(cc2)N3C(=O)C4CC=C(C)CC4C3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A07 compound treatment 670408.0 83000.0 0.37 642243.0 50200.0 0.25 0.4387 0.981 1257098 ChemDiv1_008807 Cc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A08 compound treatment 679152.0 91800.0 0.41 643614.0 51600.0 0.26 0.4712 0.974 1567285 ChemDiv1_008808 COc1ccc(OC)c(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A09 compound treatment 658834.0 71400.0 0.32 657604.0 65600.0 0.32 0.4559 1.0 1504375 ChemDiv1_008809 COC(=O)c1cc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A10 compound treatment 684165.0 96800.0 0.43 660458.0 68400.0 0.34 0.5461 0.9927 1974284 ChemDiv1_008810 CCOC(=O)c1ccc(cc1)N2C(=N)S/C(=C\c3ccc(F)cc3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A11 compound treatment 679343.0 92000.0 0.41 661069.0 69100.0 0.34 0.5329 0.9958 1721519 ChemDiv1_008811 Brc1cncc(c1)C(=O)Oc2ccc3c(=O)c(Oc4ccc5ccccc5c4)coc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A12 compound treatment 684612.0 97200.0 0.44 664172.0 72200.0 0.36 0.5605 0.9952 1210342 ChemDiv1_008812 CCOC(=O)Nc1c([nH]c2ccc(OC)cc12)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A13 compound treatment 681488.0 94100.0 0.42 643863.0 51800.0 0.26 0.4795 0.9719 1657821 ChemDiv1_008813 CC(=O)Nc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A14 compound treatment 701231.0 114000.0 0.51 676580.0 84600.0 0.42 0.6566 0.9953 1974285 ChemDiv1_008814 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A15 compound treatment 694958.0 108000.0 0.48 674645.0 82600.0 0.41 0.6299 0.9967 1974286 ChemDiv1_008815 Cc1sc2nc(SCC(=O)c3ccccc3F)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A16 compound treatment 699184.0 112000.0 0.5 659280.0 67300.0 0.33 0.5895 0.9805 1427808 ChemDiv1_008816 Cc1ccc(cc1)c2nnc(SCC(=O)n3c4CCCCc4c5ccccc35)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A17 compound treatment 694553.0 107000.0 0.48 664932.0 72900.0 0.36 0.5946 0.9902 1222056 ChemDiv1_008817 Cc1ccc(cc1)c2csc3ncnc(N4CCN(CC4)c5ccccn5)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A18 compound treatment 665680.0 78300.0 0.35 660761.0 68700.0 0.34 0.4886 0.9999 1655177 ChemDiv1_008818 COc1ccccc1NC(=O)CSCc2nc3ccccc3c(=O)n2c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A19 compound treatment 688477.0 101000.0 0.45 651736.0 59700.0 0.3 0.5292 0.9788 1974287 ChemDiv1_008819 C=CCn1c(SCC(=O)NCc2ccco2)nc3scc(c4ccccc4)c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A20 compound treatment 649393.0 62000.0 0.28 622948.0 30900.0 0.15 0.3046 0.9608 1308186 ChemDiv1_008820 CCC(=O)NCCN1CCN(CC1)C(=O)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A21 compound treatment 649555.0 62200.0 0.28 652838.0 60800.0 0.3 0.4098 0.9992 1974288 ChemDiv1_008821 COC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A22 compound treatment 618432.0 31000.0 0.14 617771.0 25800.0 0.13 0.1885 0.9991 1974289 ChemDiv1_008822 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4cccc(c4)C(=O)O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A23 mock treatment 593160.0 5770.0 0.03 595400.0 3380.0 0.02 0.0301 0.9781 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 A24 mock treatment 499710.0 -87700.0 -0.39 537020.0 -55000.0 -0.27 -0.4702 -0.9841 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B01 compound treatment 598985.0 11600.0 0.05 608502.0 16500.0 0.08 0.0944 0.976 1258843 ChemDiv1_008823 COc1ccc(cc1)N2CCN(CC2)c3nc(nc(n3)N4CCCC4)N5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B02 compound treatment 621432.0 34000.0 0.15 631755.0 39700.0 0.2 0.247 0.992 1974290 ChemDiv1_008824 CCCCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B03 compound treatment 673613.0 86200.0 0.39 688781.0 96800.0 0.48 0.6119 0.9942 1320759 ChemDiv1_008825 CC1(C)CC(CCO1)n2c(SCC=C)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B04 compound treatment 649101.0 61700.0 0.28 679463.0 87400.0 0.43 0.5016 0.9764 1447745 ChemDiv1_008826 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(Cl)c4)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B05 compound treatment 689052.0 102000.0 0.46 700035.0 108000.0 0.54 0.7002 0.9967 1974291 ChemDiv1_008827 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B06 compound treatment 681228.0 93800.0 0.42 689421.0 97400.0 0.48 0.6382 0.9976 1443479 ChemDiv1_008828 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B07 compound treatment 732598.0 145000.0 0.65 740112.0 148000.0 0.73 0.9784 0.9982 1974292 ChemDiv1_008829 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B08 compound treatment 709028.0 122000.0 0.54 724576.0 133000.0 0.66 0.8494 0.9957 1974293 ChemDiv1_008830 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B09 compound treatment 760202.0 173000.0 0.77 749722.0 158000.0 0.78 1.0994 1.0 1974294 ChemDiv1_008831 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B10 compound treatment 727637.0 140000.0 0.63 731687.0 140000.0 0.69 0.9332 0.9988 1974295 ChemDiv1_008832 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B11 compound treatment 762726.0 175000.0 0.78 750901.0 159000.0 0.79 1.1115 1.0 1974296 ChemDiv1_008833 Cc1[nH]c2ncnn2c(=O)c1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B12 compound treatment 734629.0 147000.0 0.66 729767.0 138000.0 0.68 0.9486 0.9998 1485905 ChemDiv1_008834 CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B13 compound treatment 745891.0 159000.0 0.71 757010.0 165000.0 0.82 1.0797 0.9975 1468220 ChemDiv1_008835 Cc1cc(=O)n2nc(nc2[nH]1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B14 compound treatment 711470.0 124000.0 0.56 712880.0 121000.0 0.6 0.8161 0.9993 1784308 ChemDiv1_008836 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(cc2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B15 compound treatment 759801.0 172000.0 0.77 777452.0 185000.0 0.92 1.1953 0.9962 1446401 ChemDiv1_008837 CCOC(=O)CSc1nnc2n(Cc3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B16 compound treatment 724892.0 138000.0 0.62 741466.0 149000.0 0.74 0.9587 0.9958 1494027 ChemDiv1_008838 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B17 compound treatment 748141.0 161000.0 0.72 769594.0 178000.0 0.88 1.1309 0.995 1974297 ChemDiv1_008839 COC(=O)C1=CN(CC2CCCO2)C=C(C1c3ccc(OCc4ccccc4)c(OC)c3)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B18 compound treatment 710710.0 123000.0 0.55 684287.0 92300.0 0.46 0.7136 0.9956 1162463 ChemDiv1_008840 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5cccc(Cl)c5C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B19 compound treatment 713897.0 127000.0 0.57 715591.0 124000.0 0.61 0.8333 0.9992 1493135 ChemDiv1_008841 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B20 compound treatment 690645.0 103000.0 0.46 715633.0 124000.0 0.61 0.7598 0.9904 1571017 ChemDiv1_008842 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B21 compound treatment 699771.0 112000.0 0.5 717102.0 125000.0 0.62 0.7939 0.9947 1684478 ChemDiv1_008843 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B22 compound treatment 652888.0 65500.0 0.29 672956.0 80900.0 0.4 0.4908 0.9882 1529866 ChemDiv1_008844 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B23 mock treatment 653732.0 66300.0 0.3 668461.0 76400.0 0.38 0.4778 0.9928 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 B24 mock treatment 504474.0 -82900.0 -0.37 510378.0 -81600.0 -0.4 -0.5484 -0.9991 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C01 compound treatment 611549.0 24200.0 0.11 615772.0 23800.0 0.12 0.1597 0.9991 1580089 ChemDiv1_008845 Cc1ccc(cc1S(=O)(=O)NC(C)(C)C)c2nnc(NCc3ccccc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C02 compound treatment 641385.0 54000.0 0.24 638039.0 46000.0 0.23 0.3321 0.9996 1974298 ChemDiv1_008846 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C03 compound treatment 697485.0 110000.0 0.49 680416.0 88400.0 0.44 0.6581 0.9983 1436418 ChemDiv1_008847 CNS(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C04 compound treatment 673769.0 86400.0 0.39 694778.0 103000.0 0.51 0.6334 0.9908 1334368 ChemDiv1_008848 C1CCN(CC1)c2nnc(N3CCCCC3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C05 compound treatment 714717.0 127000.0 0.57 686575.0 94600.0 0.47 0.7343 0.9953 1694632 ChemDiv1_008849 COc1ccc(Nc2nnc(C)c3ccccc23)cc1C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C06 compound treatment 701634.0 114000.0 0.51 708169.0 116000.0 0.58 0.7685 0.9983 1451390 ChemDiv1_008850 COc1ccc(OC)c(NC(=O)c2cccc(c2)N3C(=O)C4CC=C(C)CC4C3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C07 compound treatment 747631.0 160000.0 0.72 743432.0 151000.0 0.75 1.0376 0.9998 1974299 ChemDiv1_008851 Clc1ccc(NC(=O)CSc2nnc3sc4ccccc4n23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C08 compound treatment 731022.0 144000.0 0.64 741067.0 149000.0 0.74 0.9767 0.9976 1237258 ChemDiv1_008852 COc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C09 compound treatment 776014.0 189000.0 0.84 765570.0 174000.0 0.86 1.205 1.0 1361952 ChemDiv1_008853 CCN1CCN(CC1)c2nnc(c3ccc(C)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C10 compound treatment 733630.0 146000.0 0.65 735800.0 144000.0 0.71 0.9665 0.9991 1154302 ChemDiv1_008854 COc1ccc(OC)c(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C11 compound treatment 803439.0 216000.0 0.97 780067.0 188000.0 0.93 1.3426 0.9998 1403131 ChemDiv1_008855 CC(=O)Nc1nc(C)c(s1)c2cn3cccnc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C12 compound treatment 732320.0 145000.0 0.65 743775.0 152000.0 0.75 0.9903 0.9973 1568535 ChemDiv1_008856 CC(=O)Nc1c([nH]c2ccc(F)cc12)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C13 compound treatment 771638.0 184000.0 0.82 778920.0 187000.0 0.93 1.2379 0.9983 1438161 ChemDiv1_008857 COc1cc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4sc(NC(=O)C)nc4C)cc2)nc(OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C14 compound treatment 757178.0 170000.0 0.76 765115.0 173000.0 0.86 1.1438 0.9982 1974300 ChemDiv1_008858 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C15 compound treatment 796475.0 209000.0 0.94 800725.0 209000.0 1.03 1.3929 0.9988 1131260 ChemDiv1_008859 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc(cc3c1=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C16 compound treatment 750264.0 163000.0 0.73 760016.0 168000.0 0.83 1.104 0.9978 1974301 ChemDiv1_008860 Cc1ccc2N(C(=O)CSc3nnc([nH]3)c4ccccc4)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C17 compound treatment 791158.0 204000.0 0.91 793305.0 201000.0 1.0 1.3501 0.999 1390131 ChemDiv1_008861 Cc1cc(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C18 compound treatment 737769.0 150000.0 0.67 739176.0 147000.0 0.73 0.9915 0.9992 1485822 ChemDiv1_008862 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3C)oc4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C19 compound treatment 764606.0 177000.0 0.79 739658.0 148000.0 0.73 1.0781 0.9992 1974302 ChemDiv1_008863 Cc1nc(SCC(=O)c2ccc3OCOc3c2)c4c5CCCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C20 compound treatment 721774.0 134000.0 0.6 731609.0 140000.0 0.69 0.9143 0.9976 1974303 ChemDiv1_008864 COC(=O)c1ccc(CN2C(=O)C3CCCCC3C2=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C21 compound treatment 734092.0 147000.0 0.66 742470.0 150000.0 0.75 0.9914 0.998 1974304 ChemDiv1_008865 Cc1sc2ncnc(SCC(=O)Nc3ccc4ccccc4c3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C22 compound treatment 694288.0 107000.0 0.48 739335.0 147000.0 0.73 0.8544 0.9791 1974305 ChemDiv1_008866 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C23 mock treatment 675240.0 87800.0 0.39 706283.0 114000.0 0.57 0.6783 0.9842 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 C24 mock treatment 517072.0 -70300.0 -0.31 539045.0 -53000.0 -0.26 -0.4081 -0.9959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D01 compound treatment 600982.0 13600.0 0.06 599157.0 7140.0 0.04 0.068 0.9667 1474016 ChemDiv1_008867 COc1ccc(cc1)N2CCN(CC2)c3nc(OC)nc(OC)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D02 compound treatment 608867.0 21500.0 0.1 616252.0 24200.0 0.12 0.1529 0.9939 1537496 ChemDiv1_008868 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D03 compound treatment 671452.0 84100.0 0.38 686561.0 94500.0 0.47 0.5973 0.9941 1388126 ChemDiv1_008869 CC1(C)CC(CCO1)n2c(SCC#C)nc3-c4ccccc4CC5(CCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D04 compound treatment 663323.0 75900.0 0.34 675883.0 83900.0 0.42 0.5341 0.995 1246706 ChemDiv1_008870 COC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D05 compound treatment 697581.0 110000.0 0.49 712615.0 121000.0 0.6 0.7712 0.9955 1974306 ChemDiv1_008871 CC(C)(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D06 compound treatment 720142.0 133000.0 0.59 698242.0 106000.0 0.53 0.7923 0.9982 1197235 ChemDiv1_008872 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D07 compound treatment 772825.0 185000.0 0.83 818461.0 226000.0 1.12 1.3802 0.989 1381383 ChemDiv1_008873 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D08 compound treatment 691600.0 104000.0 0.47 731698.0 140000.0 0.69 0.8191 0.9816 1213683 ChemDiv1_008874 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D09 compound treatment 724082.0 137000.0 0.61 776807.0 185000.0 0.92 1.08 0.9808 1974307 ChemDiv1_008875 CCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D10 compound treatment 715782.0 128000.0 0.57 765212.0 173000.0 0.86 1.0131 0.981 1974308 ChemDiv1_008876 CCOc1cccc(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D11 compound treatment 744923.0 158000.0 0.71 789436.0 197000.0 0.98 1.1902 0.9871 1265483 ChemDiv1_008877 O=C1CCC(=O)N1c2nc3NC(=CC(c4ccccc4)n3n2)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D12 compound treatment 720605.0 133000.0 0.6 754448.0 162000.0 0.8 0.9906 0.9891 1388952 ChemDiv1_008878 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D13 compound treatment 769018.0 182000.0 0.81 781476.0 189000.0 0.94 1.2386 0.9974 1974309 ChemDiv1_008879 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCOCC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OCC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D14 compound treatment 741289.0 154000.0 0.69 757551.0 166000.0 0.82 1.067 0.9962 1974310 ChemDiv1_008880 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D15 compound treatment 723772.0 136000.0 0.61 792934.0 201000.0 1.0 1.1355 0.9725 1121338 ChemDiv1_008881 CCOC(=O)CSc1nnc2n(c3ccc(C)cc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D16 compound treatment 737459.0 150000.0 0.67 733657.0 142000.0 0.7 0.9712 0.9998 1138736 ChemDiv1_008882 COC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D17 compound treatment 788224.0 201000.0 0.9 781242.0 189000.0 0.94 1.2985 0.9998 1454965 ChemDiv1_008883 COc1cccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D18 compound treatment 718357.0 131000.0 0.59 728422.0 136000.0 0.68 0.8924 0.9975 1527628 ChemDiv1_008884 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D19 compound treatment 737464.0 150000.0 0.67 750790.0 159000.0 0.79 1.0312 0.9969 1545540 ChemDiv1_008885 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(OC)cc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D20 compound treatment 715941.0 129000.0 0.58 721601.0 130000.0 0.64 0.8608 0.9985 1447542 ChemDiv1_008886 CCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D21 compound treatment 719267.0 132000.0 0.59 756251.0 164000.0 0.81 0.9927 0.9876 1974311 ChemDiv1_008887 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D22 compound treatment 666627.0 79200.0 0.35 716888.0 125000.0 0.62 0.6882 0.9651 1974312 ChemDiv1_008888 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D23 mock treatment 672313.0 84900.0 0.38 695298.0 103000.0 0.51 0.6306 0.9893 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 D24 mock treatment 485891.0 -102000.0 -0.45 525954.0 -66100.0 -0.33 -0.5527 -0.987 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E01 compound treatment 630958.0 43600.0 0.2 625399.0 33400.0 0.17 0.2548 0.9966 1517462 ChemDiv1_008889 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3nnc(N4CCOCC4)c5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E02 compound treatment 655566.0 68200.0 0.31 662204.0 70200.0 0.35 0.4617 0.9979 1974313 ChemDiv1_008890 CCOC(=O)c1cc(NC(=O)CSc2nc(C)nc3sc4CCCCc4c23)cc(c1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E03 compound treatment 689875.0 102000.0 0.46 700616.0 109000.0 0.54 0.7048 0.9969 1325606 ChemDiv1_008891 CN(C)S(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E04 compound treatment 702708.0 115000.0 0.52 690541.0 98500.0 0.49 0.7101 0.9996 1974314 ChemDiv1_008892 Fc1ccc(NC(=O)CSc2nnc3sc4ccccc4n23)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E05 compound treatment 703214.0 116000.0 0.52 729888.0 138000.0 0.68 0.8496 0.9908 1283886 ChemDiv1_008893 COc1ccc(Nc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E06 compound treatment 737730.0 150000.0 0.67 735446.0 143000.0 0.71 0.9783 0.9996 1974315 ChemDiv1_008894 OCCNc1nc2nc(Cl)nc(N3CCCCC3)c2n1Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E07 compound treatment 754377.0 167000.0 0.75 764570.0 173000.0 0.85 1.133 0.9978 1732405 ChemDiv1_008895 C=CCn1c(SCC(=O)Nc2ccccc2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E08 compound treatment 738260.0 151000.0 0.68 751633.0 160000.0 0.79 1.0367 0.9969 1167325 ChemDiv1_008896 COc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E09 compound treatment 743065.0 156000.0 0.7 783818.0 192000.0 0.95 1.1646 0.9884 1306447 ChemDiv1_008897 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4sc5CCCCc5c4c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E10 compound treatment 729601.0 142000.0 0.64 749973.0 158000.0 0.78 1.0034 0.9948 1974316 ChemDiv1_008898 O=C(OCCN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)c4cccc5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E11 compound treatment 771632.0 184000.0 0.82 787556.0 196000.0 0.97 1.2681 0.9968 1360756 ChemDiv1_008899 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccncc4)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E12 compound treatment 752253.0 165000.0 0.74 787992.0 196000.0 0.97 1.2083 0.9908 1412577 ChemDiv1_008900 COc1ccc2[nH]c(C(=O)O)c(NC(=O)C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E13 compound treatment 715649.0 128000.0 0.57 719288.0 127000.0 0.63 0.8518 0.9989 1308483 ChemDiv1_008901 CC(=O)Nc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4cc(C)on4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E14 compound treatment 775440.0 188000.0 0.84 760513.0 168000.0 0.83 1.1855 1.0 1785277 ChemDiv1_008902 Cc1ccnc2c(NC(=O)c3ccc(cc3)N4C(=O)C5C6CC(C=C6)C5C4=O)cccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E15 compound treatment 746376.0 159000.0 0.71 805788.0 214000.0 1.06 1.252 0.9813 1974317 ChemDiv1_008903 COC(=O)c1sc(NC(=O)CSc2ncnc3sc4CCCCc4c23)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E16 compound treatment 767802.0 180000.0 0.81 775340.0 183000.0 0.91 1.2132 0.9983 1974318 ChemDiv1_008904 COc1ccc2N(C(=O)CSc3nnc([nH]3)c4ccc(C)cc4)C(C)(C)c5ssc(=S)c5-c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E17 compound treatment 793423.0 206000.0 0.92 791944.0 200000.0 0.99 1.3525 0.9994 1974319 ChemDiv1_008905 FC(F)(F)c1cc(NC(=O)CSc2nnc3sc4ccccc4n23)ccc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E18 compound treatment 753052.0 166000.0 0.74 743689.0 152000.0 0.75 1.0557 1.0 1974320 ChemDiv1_008906 [O-][N+](=O)c1ccc2C(=O)N(Cc3ccccc3)S(=O)(=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E19 compound treatment 780900.0 194000.0 0.87 742270.0 150000.0 0.74 1.1388 0.9971 1974321 ChemDiv1_008907 COc1ccc(CCNC(=O)CSc2nc(C)nc3sc4CCCCc4c23)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E20 compound treatment 755653.0 168000.0 0.75 750341.0 158000.0 0.78 1.0872 0.9998 1974322 ChemDiv1_008908 O=C(Nc1nccs1)c2ccc(cc2)N3C(=O)C4CCCCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E21 compound treatment 742093.0 155000.0 0.69 744194.0 152000.0 0.75 1.0227 0.9991 1974323 ChemDiv1_008909 CCOC(=O)c1ccc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E22 compound treatment 727456.0 140000.0 0.63 721461.0 129000.0 0.64 0.8968 0.9999 1974324 ChemDiv1_008910 CCN1C(=O)/C(=C\c2ccc(o2)c3ccc(cc3)C(=O)OC)/N(CC)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E23 mock treatment 698419.0 111000.0 0.5 726612.0 135000.0 0.67 0.8229 0.9895 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 E24 mock treatment 532850.0 -54500.0 -0.24 494539.0 -97500.0 -0.48 -0.5141 -0.9501 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F01 compound treatment 621580.0 34200.0 0.15 596475.0 4460.0 0.02 0.1238 0.8009 1592543 ChemDiv1_008911 O=c1cccc2C3CC(CN(C3)c4nc(nc(n4)N5CCOCC5)N6CCOCC6)Cn21 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F02 compound treatment 634740.0 47300.0 0.21 638909.0 46900.0 0.23 0.3141 0.999 1396412 ChemDiv1_008912 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3Br)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F03 compound treatment 651841.0 64500.0 0.29 693515.0 101000.0 0.5 0.5595 0.9652 1673438 ChemDiv1_008913 CC1(C)CC(CCO1)n2c(SCC#C)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F04 compound treatment 655678.0 68300.0 0.31 668595.0 76600.0 0.38 0.4844 0.9943 1974325 ChemDiv1_008914 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F05 compound treatment 730562.0 143000.0 0.64 721504.0 129000.0 0.64 0.9068 1.0 1303981 ChemDiv1_008915 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F06 compound treatment 684700.0 97300.0 0.44 685448.0 93400.0 0.46 0.6353 0.9995 1974326 ChemDiv1_008916 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F07 compound treatment 767519.0 180000.0 0.81 786105.0 194000.0 0.96 1.25 0.9962 1974327 ChemDiv1_008917 CCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F08 compound treatment 680483.0 93100.0 0.42 728175.0 136000.0 0.67 0.7716 0.9732 1974328 ChemDiv1_008918 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F09 compound treatment 705724.0 118000.0 0.53 753711.0 162000.0 0.8 0.941 0.9798 1974329 ChemDiv1_008919 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F10 compound treatment 703086.0 116000.0 0.52 748176.0 156000.0 0.77 0.9132 0.981 1459868 ChemDiv1_008920 CCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F11 compound treatment 703548.0 116000.0 0.52 752465.0 160000.0 0.79 0.9297 0.9788 1974330 ChemDiv1_008921 Cc1[nH]c2nc(CC(=O)O)nn2c(=O)c1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F12 compound treatment 721974.0 135000.0 0.6 741723.0 150000.0 0.74 0.9504 0.9947 1352426 ChemDiv1_008922 CCOC(=O)c1c(C)c(sc1NC(=O)C2(CC3CC4CC(C3)C2)C4)C(=O)Nc5ccc(C)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F13 compound treatment 775322.0 188000.0 0.84 772986.0 181000.0 0.9 1.2288 0.9995 1974331 ChemDiv1_008923 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1Oc4nc(Cl)ncc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F14 compound treatment 712268.0 125000.0 0.56 732760.0 141000.0 0.7 0.8883 0.994 1784309 ChemDiv1_008924 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F15 compound treatment 706417.0 119000.0 0.53 764721.0 173000.0 0.86 0.9817 0.974 1464671 ChemDiv1_008925 Cc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F16 compound treatment 740629.0 153000.0 0.69 752388.0 160000.0 0.79 1.0468 0.9973 1974332 ChemDiv1_008926 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(F)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F17 compound treatment 774661.0 187000.0 0.84 748832.0 157000.0 0.78 1.1421 0.9993 1974333 ChemDiv1_008927 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc4OCOc4c3)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F18 compound treatment 737803.0 150000.0 0.67 709164.0 117000.0 0.58 0.8865 0.9973 1391480 ChemDiv1_008928 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F19 compound treatment 773538.0 186000.0 0.83 757938.0 166000.0 0.82 1.1704 1.0 1974334 ChemDiv1_008929 CCCCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F20 compound treatment 738193.0 151000.0 0.68 749763.0 158000.0 0.78 1.0299 0.9973 1974335 ChemDiv1_008930 CCOc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F21 compound treatment 691060.0 104000.0 0.46 740544.0 149000.0 0.74 0.8484 0.9753 1470801 ChemDiv1_008931 CCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F22 compound treatment 689347.0 102000.0 0.46 674028.0 82000.0 0.41 0.61 0.9983 1673586 ChemDiv1_008932 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OCC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F23 mock treatment 690784.0 103000.0 0.46 702518.0 111000.0 0.55 0.7143 0.9965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 F24 mock treatment 483515.0 -104000.0 -0.46 488875.0 -103000.0 -0.51 -0.6901 -0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G01 compound treatment 616531.0 29100.0 0.13 623754.0 31700.0 0.16 0.2034 0.9957 1729656 ChemDiv1_008933 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3nnc(NCc4nc5ccccc5[nH]4)c6ccccc36 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G02 compound treatment 650711.0 63300.0 0.28 639875.0 47900.0 0.24 0.3681 0.9961 1974336 ChemDiv1_008934 CCOC(=O)c1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc(c1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G03 compound treatment 704374.0 117000.0 0.52 705451.0 113000.0 0.56 0.7676 0.9994 1604732 ChemDiv1_008935 CCN(CC)S(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G04 compound treatment 681922.0 94500.0 0.42 689224.0 97200.0 0.48 0.6397 0.9979 1974337 ChemDiv1_008936 COC(=O)c1c(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)sc5CCCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G05 compound treatment 706930.0 120000.0 0.54 705539.0 114000.0 0.56 0.776 0.9997 1974338 ChemDiv1_008937 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(OC)c(c3)C(=O)N)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G06 compound treatment 710558.0 123000.0 0.55 707136.0 115000.0 0.57 0.7931 0.9999 1974339 ChemDiv1_008938 CCCCNc1nc(Cl)nc2nc(NCCO)n(Cc3ccccc3)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G07 compound treatment 716267.0 129000.0 0.58 753787.0 162000.0 0.8 0.9746 0.987 1974340 ChemDiv1_008939 O=C(CSc1nnc2sc3ccccc3n12)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G08 compound treatment 695584.0 108000.0 0.48 711229.0 119000.0 0.59 0.7601 0.9952 1974341 ChemDiv1_008940 COc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G09 compound treatment 737719.0 150000.0 0.67 764394.0 172000.0 0.85 1.0797 0.993 1974342 ChemDiv1_008941 COC(=O)c1c(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)sc5CC(C)CCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G10 compound treatment 737521.0 150000.0 0.67 771114.0 179000.0 0.89 1.1026 0.9906 1494119 ChemDiv1_008942 COc1cc(cc(OC)c1OC)C(=O)Nc2cccc(c2)c3nc4cc(Cl)cc(Cl)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G11 compound treatment 764097.0 177000.0 0.79 754932.0 163000.0 0.81 1.13 0.9999 1305833 ChemDiv1_008943 Cc1nc2ccccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G12 compound treatment 750399.0 163000.0 0.73 758738.0 167000.0 0.83 1.1 0.9981 1974343 ChemDiv1_008944 COC(=O)c1[nH]c2ccccc2c1NC(=O)CN(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G13 compound treatment 740845.0 153000.0 0.69 716606.0 125000.0 0.62 0.9222 0.9986 1974344 ChemDiv1_008945 O=C(CSc1ncnc2sc(cc12)c3ccccc3)Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G14 compound treatment 775677.0 188000.0 0.84 791827.0 200000.0 0.99 1.2959 0.9968 1513371 ChemDiv1_008946 Cc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(NCCN)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G15 compound treatment 749338.0 162000.0 0.72 773402.0 181000.0 0.9 1.148 0.9943 1974345 ChemDiv1_008947 CC1CCc2c(C#N)c(NC(=O)CSc3nnc4cc(C)c5ccccc5n34)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G16 compound treatment 758570.0 171000.0 0.77 772225.0 180000.0 0.89 1.1731 0.9971 1974346 ChemDiv1_008948 CC1=CC(C)(C)N(C(=O)CSc2nnc(o2)c3ccc(C)cc3)c4ccc(C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G17 compound treatment 784590.0 197000.0 0.88 786592.0 195000.0 0.96 1.3058 0.999 1974347 ChemDiv1_008949 O=C(CSc1nnc2sc3ccccc3n12)Nc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G18 compound treatment 726273.0 139000.0 0.62 770529.0 179000.0 0.88 1.0649 0.9851 1180942 ChemDiv1_008950 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCCCc5cc4c3N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G19 compound treatment 753411.0 166000.0 0.74 794704.0 203000.0 1.0 1.2355 0.989 1974348 ChemDiv1_008951 COC(=O)c1cc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G20 compound treatment 755469.0 168000.0 0.75 721062.0 129000.0 0.64 0.984 0.9967 1407727 ChemDiv1_008952 Oc1ccccc1NC(=O)CC2SC(=O)NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G21 compound treatment 721521.0 134000.0 0.6 748716.0 157000.0 0.78 0.9735 0.9919 1974349 ChemDiv1_008953 CCOC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G22 compound treatment 723387.0 136000.0 0.61 734327.0 142000.0 0.7 0.929 0.9973 1974350 ChemDiv1_008954 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)C(=O)O)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G23 mock treatment 665593.0 78200.0 0.35 717150.0 125000.0 0.62 0.6859 0.9634 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 G24 mock treatment 511603.0 -75800.0 -0.34 534323.0 -57700.0 -0.29 -0.442 -0.9964 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H01 compound treatment 579062.0 -8330.0 -0.04 566499.0 -25500.0 -0.13 -0.1157 -0.8783 1442227 ChemDiv1_008955 O=c1cccc2C3CC(CN(C3)c4nc(nc(n4)N5CCCC5)N6CCCC6)Cn21 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H02 compound treatment 599995.0 12600.0 0.06 621720.0 29700.0 0.15 0.1439 0.9134 1974351 ChemDiv1_008956 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H03 compound treatment 658479.0 71100.0 0.32 687138.0 95100.0 0.47 0.5582 0.9817 1541496 ChemDiv1_008957 Sc1nnc(o1)C2OCCc3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H04 compound treatment 642367.0 55000.0 0.25 667638.0 75600.0 0.37 0.4389 0.9792 1784297 ChemDiv1_008958 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H05 compound treatment 721515.0 134000.0 0.6 686766.0 94800.0 0.47 0.7564 0.9926 1166831 ChemDiv1_008959 CC(C)Oc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H06 compound treatment 677464.0 90100.0 0.4 676960.0 84900.0 0.42 0.5827 0.9998 1784298 ChemDiv1_008960 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(cc4)[N+](=O)[O-])C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H07 compound treatment 711224.0 124000.0 0.55 757242.0 165000.0 0.82 0.9707 0.982 1974352 ChemDiv1_008961 CCCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H08 compound treatment 670393.0 83000.0 0.37 701323.0 109000.0 0.54 0.6456 0.9831 1360491 ChemDiv1_008962 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H09 compound treatment 680709.0 93300.0 0.42 751386.0 159000.0 0.79 0.8536 0.9557 1974353 ChemDiv1_008963 CCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H10 compound treatment 724615.0 137000.0 0.61 736946.0 145000.0 0.72 0.942 0.997 1784303 ChemDiv1_008964 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H11 compound treatment 647506.0 60100.0 0.27 760723.0 169000.0 0.84 0.7812 0.8898 1974354 ChemDiv1_008965 Cc1cc(=O)n2nc(CC(=O)O)nc2[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H12 compound treatment 729856.0 142000.0 0.64 742681.0 151000.0 0.75 0.9787 0.9969 1784306 ChemDiv1_008966 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H13 compound treatment 718800.0 131000.0 0.59 754276.0 162000.0 0.8 0.9843 0.9882 1933370 ChemDiv1_008967 COC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3[N+](=O)[O-])c(=O)n2C1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H14 compound treatment 740566.0 153000.0 0.69 755783.0 164000.0 0.81 1.0585 0.9965 1784310 ChemDiv1_008968 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(cc2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H15 compound treatment 743190.0 156000.0 0.7 793286.0 201000.0 1.0 1.1982 0.9847 1974355 ChemDiv1_008969 NC(=O)CSc1nnc2n(Cc3ccccc3)c(=O)c4c(-c5ccccc5CC64CCCCC6)n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H16 compound treatment 741654.0 154000.0 0.69 738057.0 146000.0 0.72 0.9999 0.9997 1640947 ChemDiv1_008970 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(SC)cc4)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H17 compound treatment 734439.0 147000.0 0.66 755286.0 163000.0 0.81 1.0374 0.9948 1974356 ChemDiv1_008971 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H18 compound treatment 730005.0 143000.0 0.64 736586.0 145000.0 0.72 0.9578 0.9984 1317287 ChemDiv1_008972 COC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H19 compound treatment 748065.0 161000.0 0.72 736783.0 145000.0 0.72 1.0157 1.0 1974357 ChemDiv1_008973 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H20 compound treatment 716090.0 129000.0 0.58 711927.0 120000.0 0.59 0.8274 0.9999 1124648 ChemDiv1_008974 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H21 compound treatment 749460.0 162000.0 0.73 739256.0 147000.0 0.73 1.0288 1.0 1348545 ChemDiv1_008975 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H22 compound treatment 712674.0 125000.0 0.56 717848.0 126000.0 0.62 0.8373 0.9986 1778458 ChemDiv1_008976 O=C(CCN1C(=O)c2ccccc2C1=O)N3CCN(C/C=C/c4ccccc4)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H23 mock treatment 670668.0 83300.0 0.37 690937.0 98900.0 0.49 0.6101 0.9909 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 H24 mock treatment 521883.0 -65500.0 -0.29 501951.0 -90100.0 -0.45 -0.5228 -0.9793 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I01 compound treatment 601409.0 14000.0 0.06 595900.0 3880.0 0.02 0.058 0.8834 1609524 ChemDiv1_008977 Cc1nnc(Nc2ccc(OCC(=O)N)cc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I02 compound treatment 639345.0 52000.0 0.23 648429.0 56400.0 0.28 0.3621 0.9958 1974358 ChemDiv1_008978 Cc1nc(SCCN2C(=O)c3ccccc3C2=O)c4c5CCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I03 compound treatment 676656.0 89300.0 0.4 713232.0 121000.0 0.6 0.7072 0.9804 1157122 ChemDiv1_008979 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3n[nH]c(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I04 compound treatment 681791.0 94400.0 0.42 680431.0 88400.0 0.44 0.6085 0.9998 1974359 ChemDiv1_008980 COC(=O)c1ccc(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I05 compound treatment 715268.0 128000.0 0.57 723718.0 132000.0 0.65 0.8661 0.9979 1571686 ChemDiv1_008981 Cc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I06 compound treatment 755062.0 168000.0 0.75 697031.0 105000.0 0.52 0.8986 0.984 1974360 ChemDiv1_008982 CCOC(=O)c1ccc(cc1)n2c(/C=C/c3ccc(o3)[N+](=O)[O-])nc4ccccc4c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I07 compound treatment 739489.0 152000.0 0.68 745724.0 154000.0 0.76 1.0199 0.9984 1559560 ChemDiv1_008983 Fc1ccccc1NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I08 compound treatment 714177.0 127000.0 0.57 745724.0 154000.0 0.76 0.9397 0.9895 1639467 ChemDiv1_008984 COc1ccc(CNC(=O)c2cc(nc3ccccc23)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I09 compound treatment 738837.0 151000.0 0.68 746030.0 154000.0 0.76 1.0189 0.9983 1974361 ChemDiv1_008985 COC(=O)c1c(NC(=O)CSc2nnc3sc4ccccc4n23)sc5CC(C)CCc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I10 compound treatment 707800.0 120000.0 0.54 723778.0 132000.0 0.65 0.8427 0.9955 1734531 ChemDiv1_008986 Clc1cc(Cl)c2oc(nc2c1)c3cccc(NC(=O)c4ccc5OCCOc5c4)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I11 compound treatment 733422.0 146000.0 0.65 760544.0 169000.0 0.83 1.0526 0.9927 1401343 ChemDiv1_008987 Cc1nc2sccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I12 compound treatment 758522.0 171000.0 0.77 769521.0 178000.0 0.88 1.1635 0.9976 1974362 ChemDiv1_008988 COC(=O)c1[nH]c2ccc(C)cc2c1NC(=O)CN3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I13 compound treatment 723588.0 136000.0 0.61 734416.0 142000.0 0.71 0.9299 0.9974 1974363 ChemDiv1_008989 CC1CCc2c(C#N)c(NC(=O)CSc3nnc4ccccn34)sc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I14 compound treatment 737657.0 150000.0 0.67 782610.0 191000.0 0.94 1.1433 0.9862 1974364 ChemDiv1_008990 CN(C)c1nc(Oc2ccc(OCCOc3ccccc3)nn2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I15 compound treatment 764643.0 177000.0 0.79 809086.0 217000.0 1.08 1.3214 0.9888 1974365 ChemDiv1_008991 Cc1sc2ncnc(SCC(=O)Nc3sc(cc3C(=O)N)c4ccccc4)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I16 compound treatment 711491.0 124000.0 0.56 760837.0 169000.0 0.84 0.9842 0.9803 1940370 ChemDiv1_008992 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2cccc(c2)[N+](=O)[O-])SCC(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I17 compound treatment 756281.0 169000.0 0.76 801490.0 209000.0 1.04 1.2683 0.9879 1138332 ChemDiv1_008993 C=CCn1c(SCC(=O)NCCc2ccccc2)nc3sc4CCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I18 compound treatment 718368.0 131000.0 0.59 745430.0 153000.0 0.76 0.952 0.9918 1597670 ChemDiv1_008994 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3cccc4cccnc34)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I19 compound treatment 757897.0 171000.0 0.76 753134.0 161000.0 0.8 1.1041 0.9998 1974366 ChemDiv1_008995 Cc1cc(C(=O)CSc2nnc3sc4ccccc4n23)c(C)n1c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I20 compound treatment 736654.0 149000.0 0.67 756963.0 165000.0 0.82 1.0502 0.995 1381341 ChemDiv1_008996 O=C(CC1SC(=O)NC1=O)NCc2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I21 compound treatment 721812.0 134000.0 0.6 729684.0 138000.0 0.68 0.9077 0.9981 1974367 ChemDiv1_008997 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2ncnc3sc(C)c(C)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I22 compound treatment 712084.0 125000.0 0.56 732365.0 140000.0 0.7 0.8863 0.9941 1974368 ChemDiv1_008998 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)C(c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I23 mock treatment 700905.0 114000.0 0.51 726038.0 134000.0 0.66 0.8288 0.9913 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 I24 mock treatment 513458.0 -73900.0 -0.33 539205.0 -52800.0 -0.26 -0.419 -0.9932 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J01 compound treatment 596040.0 8650.0 0.04 577658.0 -14400.0 -0.07 -0.0229 -0.283 1609010 ChemDiv1_008999 Clc1nc(NCC=C)nc(n1)N2CC3CC(C2)c4cccc(=O)n4C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J02 compound treatment 620673.0 33300.0 0.15 626431.0 34400.0 0.17 0.2259 0.9977 1360319 ChemDiv1_009000 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(OC)c4OC)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J03 compound treatment 664283.0 76900.0 0.34 660688.0 68700.0 0.34 0.4839 1.0 1683593 ChemDiv1_009001 COc1cc2CCN(C(C)c2cc1OC)C(=O)C3COc4ccccc4O3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J04 compound treatment 644987.0 57600.0 0.26 665804.0 73800.0 0.37 0.4408 0.9854 1974369 ChemDiv1_009002 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J05 compound treatment 658142.0 70800.0 0.32 683696.0 91700.0 0.45 0.5451 0.9845 1291091 ChemDiv1_009003 COc1ccc(cc1OC)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J06 compound treatment 666591.0 79200.0 0.35 683071.0 91100.0 0.45 0.5696 0.9929 1974370 ChemDiv1_009004 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(Cl)c3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J07 compound treatment 799195.0 212000.0 0.95 776782.0 185000.0 0.92 1.3176 0.9998 1974371 ChemDiv1_009005 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J08 compound treatment 711827.0 124000.0 0.56 709878.0 118000.0 0.58 0.8067 0.9997 1974372 ChemDiv1_009006 COCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3F)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J09 compound treatment 717389.0 130000.0 0.58 718212.0 126000.0 0.63 0.8535 0.9994 1974373 ChemDiv1_009007 CCCCOc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J10 compound treatment 634351.0 47000.0 0.21 705235.0 113000.0 0.56 0.5452 0.9103 1974374 ChemDiv1_009008 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J11 compound treatment 722298.0 135000.0 0.6 745464.0 153000.0 0.76 0.9645 0.9935 1974375 ChemDiv1_009009 Cc1cc(=O)n2nc(nc2[nH]1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J12 compound treatment 716234.0 129000.0 0.58 733869.0 142000.0 0.7 0.9047 0.9952 1784307 ChemDiv1_009010 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(cc4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J13 compound treatment 695920.0 109000.0 0.49 759872.0 168000.0 0.83 0.9315 0.9672 1158319 ChemDiv1_009011 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J14 compound treatment 671256.0 83900.0 0.38 676514.0 84500.0 0.42 0.5614 0.9985 1378736 ChemDiv1_009012 COC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J15 compound treatment 722325.0 135000.0 0.6 764866.0 173000.0 0.86 1.0326 0.9854 1376622 ChemDiv1_009013 CC1=C(C(NC(=O)N1)c2cc3OCOc3cc2Br)C(=O)OC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J16 compound treatment 702758.0 115000.0 0.52 750223.0 158000.0 0.78 0.9194 0.9795 1372700 ChemDiv1_009014 CCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J17 compound treatment 755044.0 168000.0 0.75 730208.0 138000.0 0.68 1.0147 0.9989 1699694 ChemDiv1_009015 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J18 compound treatment 715740.0 128000.0 0.57 720336.0 128000.0 0.64 0.8558 0.9987 1568931 ChemDiv1_009016 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(Cl)c2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J19 compound treatment 743259.0 156000.0 0.7 727631.0 136000.0 0.67 0.9684 0.9998 1523405 ChemDiv1_009017 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(OC)c(OC)c4)C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J20 compound treatment 671410.0 84000.0 0.38 714367.0 122000.0 0.61 0.6945 0.9737 1703446 ChemDiv1_009018 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J21 compound treatment 717806.0 130000.0 0.58 698318.0 106000.0 0.53 0.7852 0.9987 1974376 ChemDiv1_009019 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(OC)c3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J22 compound treatment 676173.0 88800.0 0.4 703153.0 111000.0 0.55 0.6703 0.9872 1575119 ChemDiv1_009020 Clc1ccc(CN2CCN(CC2)C(=O)CCN3C(=O)c4ccccc4C3=O)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J23 mock treatment 672764.0 85400.0 0.38 709321.0 117000.0 0.58 0.6811 0.9793 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 J24 mock treatment 506337.0 -81100.0 -0.36 498318.0 -93700.0 -0.46 -0.5848 -0.9926 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K01 compound treatment 585749.0 -1640.0 -0.01 601881.0 9870.0 0.05 0.0294 0.5941 1512847 ChemDiv1_009021 NC(=O)COc1ccc(Nc2nnc(c3ccc(Cl)cc3)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K02 compound treatment 632903.0 45500.0 0.2 634589.0 42600.0 0.21 0.2932 0.9999 1974377 ChemDiv1_009022 Cc1nc(SCC(=O)c2ccc3OCCOc3c2)c4c5CCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K03 compound treatment 689692.0 102000.0 0.46 686429.0 94400.0 0.47 0.6545 0.9999 1368040 ChemDiv1_009023 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3n[nH]c(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K04 compound treatment 683976.0 96600.0 0.43 679138.0 87100.0 0.43 0.6109 1.0 1535329 ChemDiv1_009024 CC(=O)Nc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K05 compound treatment 629185.0 41800.0 0.19 642629.0 50600.0 0.25 0.3096 0.9896 1974378 ChemDiv1_009025 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)/C=C/c3cccc4ccccc34)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K06 compound treatment 715565.0 128000.0 0.57 709525.0 118000.0 0.58 0.8173 1.0 1974379 ChemDiv1_009026 [O-][N+](=O)c1ccc(/C=C/c2nc3ccccc3c(=O)n2c4ccc(Br)cc4)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K07 compound treatment 706474.0 119000.0 0.53 738560.0 147000.0 0.73 0.8903 0.9885 1974380 ChemDiv1_009027 COC(=O)c1cc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K08 compound treatment 704164.0 117000.0 0.52 720965.0 129000.0 0.64 0.8213 0.995 1371338 ChemDiv1_009028 O=C(NCCN1CCOCC1)c2cc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K09 compound treatment 733484.0 146000.0 0.65 755032.0 163000.0 0.81 1.0335 0.9945 1974381 ChemDiv1_009029 Cc1nc(SCC(=O)Nc2sc3CCCc3c2C(=O)N)c4c5CCCc5sc4n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K10 compound treatment 689243.0 102000.0 0.46 702850.0 111000.0 0.55 0.7106 0.9957 1214189 ChemDiv1_009030 COc1cc(OC)cc(c1)C(=O)Nc2ccc3oc(nc3c2)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K11 compound treatment 723669.0 136000.0 0.61 748832.0 157000.0 0.78 0.9807 0.9928 1152745 ChemDiv1_009031 Cc1nc2ncccn2c1c3csc(Nc4ccc(cc4)S(=O)(=O)Nc5nc(C)cc(C)n5)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K12 compound treatment 695891.0 109000.0 0.49 734993.0 143000.0 0.71 0.8443 0.9831 1974382 ChemDiv1_009032 CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CN(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K13 compound treatment 720104.0 133000.0 0.59 724658.0 133000.0 0.66 0.8847 0.9987 1974383 ChemDiv1_009033 Cc1sc2ncnc(SCC(=O)NC3(CC4CC5CC(C4)C3)C5)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K14 compound treatment 696152.0 109000.0 0.49 727445.0 135000.0 0.67 0.8187 0.9876 1740484 ChemDiv1_009034 CN(C)c1nc(Oc2ccc(OCC=C)nn2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K15 compound treatment 729000.0 142000.0 0.63 766568.0 175000.0 0.86 1.0597 0.9883 1974384 ChemDiv1_009035 Fc1ccc(cc1)c2csc3nc(SCC(=O)NCc4ccc5OCOc5c4)n(CC=C)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K16 compound treatment 700274.0 113000.0 0.51 729133.0 137000.0 0.68 0.8376 0.9894 1341469 ChemDiv1_009036 CCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2)SC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K17 compound treatment 741397.0 154000.0 0.69 760807.0 169000.0 0.84 1.0787 0.9954 1974385 ChemDiv1_009037 COC(=O)c1cc(NC(=O)CSc2nc3scc(c4ccccc4)c3c(=O)n2CC=C)cc(c1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K18 compound treatment 673562.0 86200.0 0.39 732398.0 140000.0 0.7 0.7645 0.9613 1500032 ChemDiv1_009038 COC(=O)CN1C(=O)C2(C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K19 compound treatment 698409.0 111000.0 0.5 773916.0 182000.0 0.9 0.9886 0.9607 1974386 ChemDiv1_009039 COC(=O)c1sc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K20 compound treatment 721715.0 134000.0 0.6 729965.0 138000.0 0.68 0.9084 0.998 1655384 ChemDiv1_009040 O=C(CC1SC(=O)N(CN2CCOCC2)C1=O)NCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K21 compound treatment 731471.0 144000.0 0.64 727554.0 136000.0 0.67 0.9308 0.9998 1974387 ChemDiv1_009041 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nnc3ccccn23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K22 compound treatment 702354.0 115000.0 0.51 722569.0 131000.0 0.65 0.8212 0.9936 1974388 ChemDiv1_009042 Cc1cc(OCC(=O)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2)cc(C)c1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K23 mock treatment 676960.0 89600.0 0.4 727989.0 136000.0 0.67 0.7598 0.9693 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 K24 mock treatment 508944.0 -78400.0 -0.35 548228.0 -43800.0 -0.22 -0.4017 -0.9732 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L01 compound treatment 593467.0 6080.0 0.03 572693.0 -19300.0 -0.1 -0.0485 -0.4869 1547570 ChemDiv1_009043 CCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L02 compound treatment 628103.0 40700.0 0.18 609567.0 17600.0 0.09 0.1903 0.9427 1784296 ChemDiv1_009044 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)c(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L03 compound treatment 670817.0 83400.0 0.37 668799.0 76800.0 0.38 0.533 1.0 1974389 ChemDiv1_009045 COc1ccc(N/C(=C\2/C(=NN(C2=O)c3ccccc3)C)/c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L04 compound treatment 669723.0 82300.0 0.37 652516.0 60500.0 0.3 0.4725 0.9947 1441398 ChemDiv1_009046 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L05 compound treatment 702268.0 115000.0 0.51 686546.0 94500.0 0.47 0.6947 0.9989 1974390 ChemDiv1_009047 Brc1ccc2OC(N3N=C(CC3c2c1)c4ccccc4)c5ccc(OCc6ccccc6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L06 compound treatment 684627.0 97200.0 0.44 651389.0 59400.0 0.29 0.5158 0.9818 1339189 ChemDiv1_009048 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC)C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L07 compound treatment 717652.0 130000.0 0.58 705679.0 114000.0 0.56 0.8105 0.9998 1974391 ChemDiv1_009049 CC(C)c1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L08 compound treatment 645925.0 58500.0 0.26 671051.0 79000.0 0.39 0.4621 0.9809 1784300 ChemDiv1_009050 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L09 compound treatment 711071.0 124000.0 0.55 710245.0 118000.0 0.59 0.8056 0.9996 1974392 ChemDiv1_009051 Cc1[nH]c2ncnn2c(=O)c1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L10 compound treatment 673896.0 86500.0 0.39 711092.0 119000.0 0.59 0.6909 0.9792 1559816 ChemDiv1_009052 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC(C)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L11 compound treatment 693385.0 106000.0 0.47 725449.0 133000.0 0.66 0.8029 0.9868 1129234 ChemDiv1_009053 COC(=O)c1nc2[nH]c(C)cc(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L12 compound treatment 656311.0 68900.0 0.31 716319.0 124000.0 0.62 0.6536 0.9489 1525353 ChemDiv1_009054 COC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L13 compound treatment 712605.0 125000.0 0.56 722878.0 131000.0 0.65 0.8547 0.9974 1268235 ChemDiv1_009055 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC(=C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L14 compound treatment 690937.0 104000.0 0.46 712973.0 121000.0 0.6 0.7515 0.9919 1784311 ChemDiv1_009056 CCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L15 compound treatment 713892.0 127000.0 0.57 735895.0 144000.0 0.71 0.9044 0.9935 1479913 ChemDiv1_009057 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3coc4ccc(Cl)cc4c3=O)C(=O)OC5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L16 compound treatment 709733.0 122000.0 0.55 698759.0 107000.0 0.53 0.7612 0.9998 1974393 ChemDiv1_009058 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L17 compound treatment 709123.0 122000.0 0.54 711239.0 119000.0 0.59 0.8029 0.9992 1384951 ChemDiv1_009059 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L18 compound treatment 693863.0 106000.0 0.48 661346.0 69300.0 0.34 0.5799 0.9871 1784314 ChemDiv1_009060 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L19 compound treatment 718005.0 131000.0 0.58 718870.0 127000.0 0.63 0.8578 0.9994 1784295 ChemDiv1_009061 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L20 compound treatment 698783.0 111000.0 0.5 700244.0 108000.0 0.54 0.7317 0.9993 1974394 ChemDiv1_009062 CCOc1ccccc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OCCOC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L21 compound treatment 736822.0 149000.0 0.67 719535.0 128000.0 0.63 0.9197 0.9996 1416416 ChemDiv1_009063 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(OC)c(OC)c(OC)c2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L22 compound treatment 699463.0 112000.0 0.5 721699.0 130000.0 0.64 0.809 0.9925 1596703 ChemDiv1_009064 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L23 mock treatment 678540.0 91100.0 0.41 693419.0 101000.0 0.5 0.6437 0.9947 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 L24 mock treatment 499982.0 -87400.0 -0.39 503280.0 -88700.0 -0.44 -0.5875 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M01 compound treatment 600015.0 12600.0 0.06 593974.0 1960.0 0.01 0.0468 0.8166 1463851 ChemDiv1_009065 CNC(=O)COc1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)NC(C)C)c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M02 compound treatment 625372.0 38000.0 0.17 628111.0 36100.0 0.18 0.2467 0.9997 1392303 ChemDiv1_009066 COC(=O)c1c(C)[nH]c(C(=O)CSc2nc(C)nc3sc4CCCc4c23)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M03 compound treatment 675292.0 87900.0 0.39 669979.0 78000.0 0.39 0.5513 1.0 1721115 ChemDiv1_009067 CC(C)NS(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M04 compound treatment 658214.0 70800.0 0.32 669877.0 77900.0 0.39 0.4969 0.9953 1974395 ChemDiv1_009068 COC(=O)c1sc(NC(=O)CSc2ncnc3sc4CCCc4c23)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M05 compound treatment 683119.0 95700.0 0.43 695258.0 103000.0 0.51 0.6647 0.9961 1390522 ChemDiv1_009069 CCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(C)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M06 compound treatment 644690.0 57300.0 0.26 661182.0 69200.0 0.34 0.4236 0.9898 1723377 ChemDiv1_009070 CCCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccccc2Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M07 compound treatment 706169.0 119000.0 0.53 708143.0 116000.0 0.58 0.7827 0.9992 1319057 ChemDiv1_009071 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nc(C)nc3sc4CCCc4c23)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M08 compound treatment 683192.0 95800.0 0.43 692991.0 101000.0 0.5 0.6569 0.9971 1738083 ChemDiv1_009072 Clc1ccc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)nc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M09 compound treatment 668072.0 80700.0 0.36 719219.0 127000.0 0.63 0.701 0.9651 1177071 ChemDiv1_009073 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4sc5CCCc5c4c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M10 compound treatment 696528.0 109000.0 0.49 670273.0 78300.0 0.39 0.6196 0.9934 1210198 ChemDiv1_009074 CCOC(=O)c1[nH]c2ccc(F)cc2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M11 compound treatment 719594.0 132000.0 0.59 737115.0 145000.0 0.72 0.9267 0.9953 1662182 ChemDiv1_009075 Cc1nc(N)sc1c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M12 compound treatment 680820.0 93400.0 0.42 698202.0 106000.0 0.53 0.6677 0.9935 1974396 ChemDiv1_009076 CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CN3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M13 compound treatment 713807.0 126000.0 0.57 719981.0 128000.0 0.63 0.8484 0.9984 1390009 ChemDiv1_009077 Cc1sc2nc(SCc3ccc4OCOc4c3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M14 compound treatment 709842.0 122000.0 0.55 718208.0 126000.0 0.63 0.8296 0.9979 1325589 ChemDiv1_009078 CN(C)c1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M15 compound treatment 713770.0 126000.0 0.57 737014.0 145000.0 0.72 0.9079 0.993 1974397 ChemDiv1_009079 O=C(CSc1ncnc2sc3CCCc3c12)NCc4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M16 compound treatment 712137.0 125000.0 0.56 711796.0 120000.0 0.59 0.8144 0.9995 1974398 ChemDiv1_009080 Cc1ccc(cc1)S(=O)(=O)Oc2ccc(Cl)cc2C=c3sc4nc5ccccc5n4c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M17 compound treatment 732938.0 146000.0 0.65 714855.0 123000.0 0.61 0.891 0.9994 1552735 ChemDiv1_009081 C=CCn1c(SCC(=O)Nc2ccc3OCOc3c2)nc4sc5CCCc5c4c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M18 compound treatment 703112.0 116000.0 0.52 702743.0 111000.0 0.55 0.7542 0.9996 1675759 ChemDiv1_009082 CC(=C)CSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M19 compound treatment 726109.0 139000.0 0.62 747521.0 156000.0 0.77 0.9838 0.9943 1974399 ChemDiv1_009083 COC(=O)c1sc(NC(=O)CSc2nnc3cc(C)c4ccccc4n23)c(C(=O)OC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M20 compound treatment 696760.0 109000.0 0.49 707500.0 115000.0 0.57 0.7507 0.997 1974400 ChemDiv1_009084 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=NN(C3=O)c4ccc(C)c(Cl)c4)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M21 compound treatment 729866.0 142000.0 0.64 743031.0 151000.0 0.75 0.98 0.9968 1974401 ChemDiv1_009085 FC(F)(F)c1ccccc1NC(=O)CSc2ncnc3sc4CCCc4c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M22 compound treatment 706531.0 119000.0 0.53 708320.0 116000.0 0.58 0.7845 0.9993 1974402 ChemDiv1_009086 Brc1ccc(OCC(=O)Nc2ccc3C(=O)c4ccccc4C(=O)c3c2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M23 mock treatment 664589.0 77200.0 0.35 707266.0 115000.0 0.57 0.6481 0.9711 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 M24 mock treatment 620652.0 33300.0 0.15 409689.0 -182000.0 -0.9 -0.5334 -0.5827 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N01 compound treatment 603232.0 15800.0 0.07 593386.0 1370.0 0.01 0.0549 0.7713 1297789 ChemDiv1_009087 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N02 compound treatment 626585.0 39200.0 0.18 614126.0 22100.0 0.11 0.2015 0.9743 1278880 ChemDiv1_009088 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4Cl)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N03 compound treatment 629591.0 42200.0 0.19 664085.0 72100.0 0.36 0.386 0.9557 1974403 ChemDiv1_009089 CC/1=NN(C(=O)\C1=C(/Nc2cccc(C)c2)\c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N04 compound treatment 651974.0 64600.0 0.29 651050.0 59000.0 0.29 0.4112 1.0 1488693 ChemDiv1_009090 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N05 compound treatment 694278.0 107000.0 0.48 662549.0 70500.0 0.35 0.5854 0.9881 1974404 ChemDiv1_009091 CCCCOc1ccc(cc1)C2Oc3ccccc3C4CC(=NN42)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N06 compound treatment 647580.0 60200.0 0.27 648333.0 56300.0 0.28 0.3878 0.9998 1498868 ChemDiv1_009092 CCOC(=O)c1c(C)c(sc1NC(=O)CCc2ccccc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N07 compound treatment 666360.0 79000.0 0.35 690679.0 98700.0 0.49 0.5956 0.9873 1974405 ChemDiv1_009093 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N08 compound treatment 638583.0 51200.0 0.23 670179.0 78200.0 0.39 0.4358 0.9687 1974406 ChemDiv1_009094 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N09 compound treatment 659172.0 71800.0 0.32 665308.0 73300.0 0.36 0.4839 0.9981 1974407 ChemDiv1_009095 COC(=O)c1nc2[nH]c(C)c([N+](=O)[O-])c(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N10 compound treatment 687730.0 100000.0 0.45 689899.0 97900.0 0.48 0.6605 0.9993 1311379 ChemDiv1_009096 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cc(C)ccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N11 compound treatment 708388.0 121000.0 0.54 702917.0 111000.0 0.55 0.7715 1.0 1974408 ChemDiv1_009097 CCOC(=O)c1nc2[nH]c(C)cc(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N12 compound treatment 676087.0 88700.0 0.4 670534.0 78500.0 0.39 0.5558 0.9999 1141481 ChemDiv1_009098 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N13 compound treatment 688353.0 101000.0 0.45 684573.0 92600.0 0.46 0.6438 1.0 1282501 ChemDiv1_009099 CCOC(=O)CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N14 compound treatment 661867.0 74500.0 0.33 671126.0 79100.0 0.39 0.5129 0.9968 1148133 ChemDiv1_009100 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N15 compound treatment 702201.0 115000.0 0.51 691259.0 99200.0 0.49 0.711 0.9998 1974409 ChemDiv1_009101 COC(=O)C1=CN(CC2CCCO2)C=C(C1c3ccc(OC)c(OCc4ccccc4)c3)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N16 compound treatment 639582.0 52200.0 0.23 674551.0 82500.0 0.41 0.4543 0.9648 1650518 ChemDiv1_009102 COC(=O)C1=C(C)NC2=C(C1c3cccc(Br)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N17 compound treatment 728037.0 141000.0 0.63 707987.0 116000.0 0.57 0.8514 0.999 1974410 ChemDiv1_009103 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)cc3Cl)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N18 compound treatment 693215.0 106000.0 0.47 684171.0 92200.0 0.46 0.6578 0.9998 1784315 ChemDiv1_009104 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(c4)[N+](=O)[O-])C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N19 compound treatment 697157.0 110000.0 0.49 709664.0 118000.0 0.58 0.7595 0.9964 1181180 ChemDiv1_009105 CCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N20 compound treatment 705812.0 118000.0 0.53 687598.0 95600.0 0.47 0.7096 0.9984 1284579 ChemDiv1_009106 CCCOC(=O)C1=C(C)NC2=C(C1c3ccccc3OCC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N21 compound treatment 722758.0 135000.0 0.61 685448.0 93400.0 0.46 0.7558 0.9912 1974411 ChemDiv1_009107 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N22 compound treatment 621328.0 33900.0 0.15 693944.0 102000.0 0.5 0.4645 0.8808 1974412 ChemDiv1_009108 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N23 mock treatment 660341.0 73000.0 0.33 665423.0 73400.0 0.36 0.488 0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 N24 mock treatment 297127.0 -290000.0 -1.3 381328.0 -211000.0 -1.04 -1.6568 -0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O01 compound treatment 594333.0 6940.0 0.03 589078.0 -2940.0 -0.01 0.0117 0.3405 1974413 ChemDiv1_009109 CCOC(=O)CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3cccc(Br)c3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O02 compound treatment 610353.0 23000.0 0.1 600391.0 8380.0 0.04 0.102 0.9204 1974414 ChemDiv1_009110 O=C(CSc1ncnc2sc3CCCc3c12)CC(=O)Nc4sc5CCCCc5c4C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O03 compound treatment 653758.0 66400.0 0.3 633106.0 41100.0 0.2 0.354 0.983 1376162 ChemDiv1_009111 Cc1ccc(cc1S(=O)(=O)NC(C)(C)C)c2n[nH]c(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O04 compound treatment 632845.0 45500.0 0.2 629024.0 37000.0 0.18 0.2735 0.9986 1974415 ChemDiv1_009112 O=C(CSc1ncnc2sc3CCCCc3c12)Nc4sccc4C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O05 compound treatment 654046.0 66700.0 0.3 640555.0 48500.0 0.24 0.381 0.9943 1974416 ChemDiv1_009113 Cc1sc2nc(SCC(=O)Nc3ccc(C)cc3)n(CC=C)c(=O)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O06 compound treatment 657554.0 70200.0 0.31 626659.0 34600.0 0.17 0.3434 0.9596 1692259 ChemDiv1_009114 Cc1cc(NCCN)nc(NS(=O)(=O)c2ccccc2Cl)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O07 compound treatment 669161.0 81800.0 0.37 644448.0 52400.0 0.26 0.4425 0.9859 1691550 ChemDiv1_009115 CN1CCN(CC1)c2nnc(c3ccc(C)c(C)c3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O08 compound treatment 620972.0 33600.0 0.15 645034.0 53000.0 0.26 0.292 0.9649 1930239 ChemDiv1_009116 COc1cc(ccc1NC(=O)c2cc(nc3ccccc23)c4ccccc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O09 compound treatment 670286.0 82900.0 0.37 687863.0 95800.0 0.47 0.5981 0.9926 1974417 ChemDiv1_009117 CC(C)c1ccc(/C=C(\C#N)/C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O10 compound treatment 645600.0 58200.0 0.26 640653.0 48600.0 0.24 0.3546 0.9992 1629180 ChemDiv1_009118 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O11 compound treatment 658223.0 70800.0 0.32 660331.0 68300.0 0.34 0.4635 0.9995 1270995 ChemDiv1_009119 Cc1nc(C)c(s1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O12 compound treatment 649218.0 61800.0 0.28 655976.0 64000.0 0.32 0.4197 0.9977 1974418 ChemDiv1_009120 CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)CN(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O13 compound treatment 660996.0 73600.0 0.33 664268.0 72300.0 0.36 0.4861 0.9991 1974419 ChemDiv1_009121 CCOC(=O)c1c(C)c(sc1NC(=O)CSc2nc(C)nc3sc4CCCc4c23)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O14 compound treatment 652927.0 65500.0 0.29 651771.0 59800.0 0.3 0.4168 1.0 1427171 ChemDiv1_009122 CC(C)OC(=O)c1sc2nc(N3CCOCC3)c4COC(C)(C)Cc4c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O15 compound treatment 692429.0 105000.0 0.47 697329.0 105000.0 0.52 0.7014 0.9987 1974420 ChemDiv1_009123 C=CCn1c(SCC(=O)NCc2ccc3OCOc3c2)nc4scc(c5ccccc5)c4c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O16 compound treatment 647745.0 60400.0 0.27 659834.0 67800.0 0.34 0.4286 0.9942 1974421 ChemDiv1_009124 OC1(C(=O)N2c3c1cccc3Sc4ccccc24)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O17 compound treatment 691700.0 104000.0 0.47 688516.0 96500.0 0.48 0.6682 0.9999 1216842 ChemDiv1_009125 COC(=O)c1c(C)[nH]c(C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O18 compound treatment 665437.0 78000.0 0.35 667324.0 75300.0 0.37 0.5108 0.9995 1974422 ChemDiv1_009126 CCOCCSc1nc2-c3ccccc3CC(C)(C4CCCCC4)c2c(=O)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O19 compound treatment 674155.0 86800.0 0.39 683758.0 91700.0 0.45 0.596 0.9969 1974423 ChemDiv1_009127 COC(=O)c1c(NC(=O)CSc2ncnc3sc(C)c(C)c23)sc4CCCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O20 compound treatment 654557.0 67200.0 0.3 659979.0 68000.0 0.34 0.4507 0.9984 1974424 ChemDiv1_009128 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=NN(C3=O)c4ccc(Cl)c(c4)C(=O)O)C)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O21 compound treatment 671939.0 84500.0 0.38 684466.0 92500.0 0.46 0.5915 0.9955 1516804 ChemDiv1_009129 COC(=O)c1c(C)[nH]c(C(=O)CSc2ncnc3sc4CCCc4c23)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O22 compound treatment 625940.0 38500.0 0.17 659812.0 67800.0 0.34 0.3595 0.9521 1690227 ChemDiv1_009130 COc1ccc(cc1)N2CCN(CC2)c3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O23 mock treatment 636271.0 48900.0 0.22 657550.0 65500.0 0.32 0.3843 0.9816 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 O24 mock treatment 187361.0 -400000.0 -1.79 441891.0 -150000.0 -0.74 -1.7921 -0.9242 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P01 compound treatment 561769.0 -25600.0 -0.11 541022.0 -51000.0 -0.25 -0.2597 -0.9362 1974425 ChemDiv1_009131 CCCCSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P02 compound treatment 576395.0 -11000.0 -0.05 552352.0 -39700.0 -0.2 -0.1737 -0.8577 1718407 ChemDiv1_009132 COC(=O)C1=C(C)NC2=C(C1c3cc(OC)ccc3OC)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P03 compound treatment 579118.0 -8270.0 -0.04 556256.0 -35800.0 -0.18 -0.1514 -0.8368 1974426 ChemDiv1_009133 CC1=NN(C(=O)c2ccccc2Br)C(O)(C1)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P04 compound treatment 581800.0 -5590.0 -0.03 572918.0 -19100.0 -0.09 -0.0846 -0.8644 1974427 ChemDiv1_009134 COCCOC(=O)C1=C(C)NC2=C(C1c3cccc(C)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P05 compound treatment 602231.0 14800.0 0.07 582981.0 -9030.0 -0.04 0.0153 0.1914 1974428 ChemDiv1_009135 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5ccc(cc5)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P06 compound treatment 574637.0 -12800.0 -0.06 563534.0 -28500.0 -0.14 -0.1401 -0.9207 1616758 ChemDiv1_009136 COC(=O)C1=C(C)NC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P07 compound treatment 599958.0 12600.0 0.06 564765.0 -27300.0 -0.13 -0.0557 -0.3807 1369310 ChemDiv1_009137 COc1ccc(cc1OC)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P08 compound treatment 590919.0 3530.0 0.02 567489.0 -24500.0 -0.12 -0.0747 -0.6101 1784301 ChemDiv1_009138 CCOC(=O)c1c(C)c(sc1NC(=O)c2cccc(c2)[N+](=O)[O-])C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P09 compound treatment 613536.0 26100.0 0.12 578788.0 -13200.0 -0.07 0.0364 0.2716 1974429 ChemDiv1_009139 CCOC(=O)Cc1nc2[nH]c(C)c([N+](=O)[O-])c(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P10 compound treatment 575600.0 -11800.0 -0.05 553591.0 -38400.0 -0.19 -0.1719 -0.8703 1468687 ChemDiv1_009140 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(SC)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P11 compound treatment 602340.0 14900.0 0.07 586332.0 -5680.0 -0.03 0.0274 0.3776 1974430 ChemDiv1_009141 CCOC(=O)Cc1nc2[nH]c(C)cc(=O)n2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P12 compound treatment 608095.0 20700.0 0.09 573507.0 -18500.0 -0.09 7.0E-4 0.0054 1559230 ChemDiv1_009142 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3cccc(Cl)c3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P13 compound treatment 601885.0 14500.0 0.06 579232.0 -12800.0 -0.06 0.0011 0.0121 1528958 ChemDiv1_009143 COc1ccccc1n2c(SCC(=O)N)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P14 compound treatment 596268.0 8880.0 0.04 582007.0 -10000.0 -0.05 -0.007 -0.1095 1119971 ChemDiv1_009144 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4OC(C)C)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P15 compound treatment 698486.0 111000.0 0.5 585532.0 -6480.0 -0.03 0.3289 0.6601 1479435 ChemDiv1_009145 COc1ccc(OC)c(c1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P16 compound treatment 653551.0 66200.0 0.3 617676.0 25700.0 0.13 0.2993 0.9287 1672402 ChemDiv1_009146 CCOC(=O)c1c(C)c(sc1NC(=O)Cc2ccc(Cl)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P17 compound treatment 645466.0 58100.0 0.26 583422.0 -8590.0 -0.04 0.1537 0.5835 1784294 ChemDiv1_009147 CCOC(=O)c1c(C)c(sc1NC(=O)c2ccc(C)c(c2)[N+](=O)[O-])C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P18 compound treatment 655695.0 68300.0 0.31 578861.0 -13200.0 -0.07 0.1701 0.5442 1318406 ChemDiv1_009148 CCOc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccc(OC)c(OC)c4)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P19 compound treatment 645946.0 58600.0 0.26 607024.0 15000.0 0.07 0.2379 0.8732 1199977 ChemDiv1_009149 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4cccc(OC)c4OC)C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P20 compound treatment 621596.0 34200.0 0.15 596516.0 4500.0 0.02 0.124 0.8016 1376915 ChemDiv1_009150 CCOC(=O)C1=C(C)NC2=C(C1c3ccc(Br)cc3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P21 compound treatment 624501.0 37100.0 0.17 591716.0 -299.0 0.0 0.1164 0.7008 1128673 ChemDiv1_009151 CCOC(=O)c1c(C)c(sc1NC(=O)COc2ccccc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P22 compound treatment 705270.0 118000.0 0.53 682679.0 90700.0 0.45 0.6907 0.9968 1567848 ChemDiv1_009152 CC(=O)Oc1ccc(C2Nc3ccc4ccccc4c3C5C=CCC52)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P23 mock treatment 607953.0 20600.0 0.09 576595.0 -15400.0 -0.08 0.0111 0.0925 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.612 P24 mock treatment 178745.0 -409000.0 -1.83 524199.0 -67800.0 -0.34 -1.531 -0.8232 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A01 compound treatment 613638.0 -4960.0 -0.02 594816.0 -23700.0 -0.12 -0.0986 -0.8263 1719174 ChemDiv1_009153 CN(C)C(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A02 compound treatment 611491.0 -7110.0 -0.03 596611.0 -21900.0 -0.11 -0.0991 -0.8777 1974431 ChemDiv1_009154 CN1CCN(CC1)C(=O)/C(=C\c2cccnc2)/NC(=O)c3ccco3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A03 compound treatment 624829.0 6230.0 0.03 616527.0 -1950.0 -0.01 0.0129 0.4362 1160549 ChemDiv1_009155 COC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A04 compound treatment 616602.0 -2000.0 -0.01 629693.0 11200.0 0.06 0.033 0.5859 1974432 ChemDiv1_009156 COc1ccccc1N2CCN(CC2)C(=O)/C(=C/c3ccccc3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A05 compound treatment 648800.0 30200.0 0.14 634076.0 15600.0 0.08 0.1502 0.9648 1210424 ChemDiv1_009157 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A06 compound treatment 650817.0 32200.0 0.14 652414.0 33900.0 0.17 0.2208 0.9971 1974433 ChemDiv1_009158 Cc1ccc(o1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A07 compound treatment 641931.0 23300.0 0.1 647580.0 29100.0 0.14 0.1758 0.9875 1974434 ChemDiv1_009159 COc1ccc2oc(C(=O)C)c(N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A08 compound treatment 685522.0 66900.0 0.3 677478.0 59000.0 0.29 0.4185 0.9999 1974435 ChemDiv1_009160 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A09 compound treatment 682737.0 64100.0 0.29 662995.0 44500.0 0.22 0.3589 0.9915 1974436 ChemDiv1_009161 CCOC(=O)c1c(CN(C(=O)CN2CCCCC2)c3ccccc3)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A10 compound treatment 665753.0 47200.0 0.21 672505.0 54000.0 0.27 0.3385 0.9931 1121736 ChemDiv1_009162 COc1cc(cc(Br)c1O)C2CC(=O)NC(=C2C#N)SCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A11 compound treatment 688432.0 69800.0 0.31 666729.0 48200.0 0.24 0.3901 0.9912 1232969 ChemDiv1_009163 COC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A12 compound treatment 671005.0 52400.0 0.23 677407.0 58900.0 0.29 0.3723 0.9941 1974437 ChemDiv1_009164 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccco4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A13 compound treatment 691709.0 73100.0 0.33 685731.0 67200.0 0.33 0.467 1.0 1377105 ChemDiv1_009165 CCOC(=O)Cc1nnc(NC(=O)CSc2nnc3c4ccccc4n(CC=C)c3n2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A14 compound treatment 677869.0 59300.0 0.27 673585.0 55100.0 0.27 0.3806 0.9999 1974438 ChemDiv1_009166 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A15 compound treatment 687877.0 69300.0 0.31 658902.0 40400.0 0.2 0.3609 0.9776 1974439 ChemDiv1_009167 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccc(C)cc3nc2N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A16 compound treatment 692315.0 73700.0 0.33 706908.0 88400.0 0.44 0.5431 0.9902 1241290 ChemDiv1_009168 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2CC)C#N)c3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A17 compound treatment 696699.0 78100.0 0.35 678737.0 60300.0 0.3 0.4583 0.9969 1717377 ChemDiv1_009169 CNC(=O)N(C)c1nnc(o1)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A18 compound treatment 688850.0 70300.0 0.31 665805.0 47300.0 0.23 0.3881 0.9895 1974440 ChemDiv1_009170 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A19 compound treatment 690868.0 72300.0 0.32 672684.0 54200.0 0.27 0.4186 0.9957 1192805 ChemDiv1_009171 Cc1nc2ncnc(c3ccccc3)c2n1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A20 compound treatment 656628.0 38000.0 0.17 634881.0 16400.0 0.08 0.1778 0.9427 1492604 ChemDiv1_009172 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A21 compound treatment 658291.0 39700.0 0.18 646071.0 27600.0 0.14 0.2223 0.9916 1974441 ChemDiv1_009173 COc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A22 compound treatment 631817.0 13200.0 0.06 641646.0 23200.0 0.11 0.123 0.9525 1544308 ChemDiv1_009174 Cc1cccc(C)c1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A23 mock treatment 621672.0 3070.0 0.01 630900.0 12400.0 0.06 0.0532 0.8444 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 A24 mock treatment 518704.0 -99900.0 -0.45 537427.0 -81100.0 -0.4 -0.6001 -0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B01 compound treatment 598682.0 -19900.0 -0.09 600226.0 -18300.0 -0.09 -0.127 -1.0 1974442 ChemDiv1_009175 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3ccc(OC)c(O)c3)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B02 compound treatment 640598.0 22000.0 0.1 646266.0 27800.0 0.14 0.167 0.9865 1430173 ChemDiv1_009176 CCN(CC)c1cc(C)nc(NCc2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B03 compound treatment 700803.0 82200.0 0.37 705394.0 86900.0 0.43 0.5646 0.9969 1974443 ChemDiv1_009177 COc1cccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c1OCc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B04 compound treatment 701956.0 83400.0 0.37 694513.0 76000.0 0.38 0.5302 1.0 1389532 ChemDiv1_009178 COC(=O)CSc1nnc2n(C3CCCCC3)c(=O)c4c5CCCCc5sc4n12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B05 compound treatment 724566.0 106000.0 0.47 735743.0 117000.0 0.58 0.7462 0.9949 1974444 ChemDiv1_009179 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4F)C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B06 compound treatment 699300.0 80700.0 0.36 706857.0 88400.0 0.44 0.565 0.9954 1974445 ChemDiv1_009180 COc1cc(OC)c(cc1OC)C2C(=C(N)Oc3[nH]nc(c23)c4cc(OC)c(OC)c(OC)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B07 compound treatment 743185.0 125000.0 0.56 742294.0 124000.0 0.61 0.8281 0.9989 1974446 ChemDiv1_009181 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B08 compound treatment 709763.0 91200.0 0.41 673915.0 55400.0 0.27 0.4827 0.9814 1974447 ChemDiv1_009182 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccc6OCOc6c5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B09 compound treatment 749693.0 131000.0 0.59 724354.0 106000.0 0.52 0.7858 0.9984 1974448 ChemDiv1_009183 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B10 compound treatment 743689.0 125000.0 0.56 747677.0 129000.0 0.64 0.8485 0.9978 1281703 ChemDiv1_009184 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B11 compound treatment 744028.0 125000.0 0.56 749513.0 131000.0 0.65 0.856 0.9974 1703653 ChemDiv1_009185 CC(C(=O)c1ccccc1)C2(O)C(=O)N(Cc3ccccc3C)c4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B12 compound treatment 737854.0 119000.0 0.53 735149.0 117000.0 0.58 0.7862 0.9992 1250498 ChemDiv1_009186 COc1cccc(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B13 compound treatment 768045.0 149000.0 0.67 743420.0 125000.0 0.62 0.9107 0.9992 1974449 ChemDiv1_009187 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B14 compound treatment 752875.0 134000.0 0.6 740294.0 122000.0 0.6 0.8517 1.0 1519435 ChemDiv1_009188 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B15 compound treatment 777265.0 159000.0 0.71 781704.0 163000.0 0.81 1.074 0.9979 1871204 ChemDiv1_009189 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccccc5c4=O)C(=O)OCC6CCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B16 compound treatment 749559.0 131000.0 0.59 745557.0 127000.0 0.63 0.8597 0.9994 1180617 ChemDiv1_009190 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(Br)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B17 compound treatment 785926.0 167000.0 0.75 779953.0 161000.0 0.8 1.0953 0.9995 1974450 ChemDiv1_009191 CCOCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B18 compound treatment 723409.0 105000.0 0.47 753522.0 135000.0 0.67 0.8048 0.9849 1941557 ChemDiv1_009192 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B19 compound treatment 725072.0 106000.0 0.48 733389.0 115000.0 0.57 0.7395 0.9961 1871375 ChemDiv1_009193 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(O)c(c3)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B20 compound treatment 711722.0 93100.0 0.42 731787.0 113000.0 0.56 0.6917 0.9893 1533763 ChemDiv1_009194 COc1cccc(C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B21 compound treatment 745062.0 126000.0 0.57 734489.0 116000.0 0.57 0.8067 1.0 1974451 ChemDiv1_009195 OCCCn1c(/C=C/c2cn(Cc3ccccc3)c4ccccc24)nc5ccccc5c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B22 compound treatment 690774.0 72200.0 0.32 705719.0 87200.0 0.43 0.534 0.9897 1974452 ChemDiv1_009196 COCCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(C)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B23 mock treatment 685487.0 66900.0 0.3 697636.0 79200.0 0.39 0.489 0.9911 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 B24 mock treatment 502244.0 -116000.0 -0.52 517732.0 -101000.0 -0.5 -0.7212 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C01 compound treatment 632061.0 13500.0 0.06 618749.0 268.0 0.0 0.0436 0.7225 1176544 ChemDiv1_009197 Oc1ccccc1c2nc(NCCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C02 compound treatment 658417.0 39800.0 0.18 653706.0 35200.0 0.17 0.2494 0.9999 1974453 ChemDiv1_009198 COc1ccc(/C=C(/NC(=O)c2cccc(C)c2)\C(=O)NCCc3c[nH]c4ccccc34)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C03 compound treatment 737059.0 118000.0 0.53 718993.0 101000.0 0.5 0.727 0.9995 1974454 ChemDiv1_009199 FC(F)(F)c1cc(nc(n1)N2CCOCC2)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C04 compound treatment 755152.0 137000.0 0.61 725776.0 107000.0 0.53 0.8081 0.9976 1974455 ChemDiv1_009200 Cc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)NCCc3c[nH]c4ccccc34)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C05 compound treatment 760921.0 142000.0 0.64 755263.0 137000.0 0.68 0.9296 0.9995 1332750 ChemDiv1_009201 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C06 compound treatment 728114.0 110000.0 0.49 714679.0 96200.0 0.48 0.6836 0.9999 1200050 ChemDiv1_009202 CCOc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C07 compound treatment 756987.0 138000.0 0.62 796054.0 178000.0 0.88 1.0601 0.9853 1597231 ChemDiv1_009203 COc1ccc2occ(C(=O)c3oc4ccc(Cl)cc4c3N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C08 compound treatment 756245.0 138000.0 0.62 763463.0 145000.0 0.72 0.9435 0.9971 1974456 ChemDiv1_009204 Cc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C09 compound treatment 783266.0 165000.0 0.74 805424.0 187000.0 0.93 1.1761 0.9936 1500182 ChemDiv1_009205 COC(=O)c1oc2ccc(Cl)cc2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C10 compound treatment 777596.0 159000.0 0.71 752172.0 134000.0 0.66 0.9716 0.9994 1974457 ChemDiv1_009206 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C11 compound treatment 792504.0 174000.0 0.78 804276.0 186000.0 0.92 1.2013 0.9965 1140405 ChemDiv1_009207 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCCN3C(=O)c4ccccc4C3=O)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C12 compound treatment 773538.0 155000.0 0.69 772373.0 154000.0 0.76 1.0295 0.9989 1199486 ChemDiv1_009208 CCc1ccc(NC(=O)CSC2=C(C#N)C(C(=C(C)N2)C(=O)OC)c3ccccc3Cl)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C13 compound treatment 812027.0 193000.0 0.87 831088.0 213000.0 1.05 1.357 0.9953 1974458 ChemDiv1_009209 Oc1ccc(Cl)cc1C2=NNC(C2)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C14 compound treatment 725650.0 107000.0 0.48 750428.0 132000.0 0.65 0.801 0.9884 1591482 ChemDiv1_009210 CC1=C(C(C(=C(N1)SCC(=O)N)C#N)c2ccc(Cl)cc2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C15 compound treatment 832365.0 214000.0 0.96 826928.0 208000.0 1.03 1.4068 0.9993 1974459 ChemDiv1_009211 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccc(C)cc3nc2N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C16 compound treatment 786521.0 168000.0 0.75 811665.0 193000.0 0.96 1.2082 0.9929 1974460 ChemDiv1_009212 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C17 compound treatment 811781.0 193000.0 0.86 801857.0 183000.0 0.91 1.2538 0.9997 1270904 ChemDiv1_009213 CCOC(=O)COc1nc(C)c(Br)c(COC)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C18 compound treatment 772671.0 154000.0 0.69 775926.0 157000.0 0.78 1.0392 0.9981 1974461 ChemDiv1_009214 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C19 compound treatment 790803.0 172000.0 0.77 783265.0 165000.0 0.82 1.1223 0.9996 1974462 ChemDiv1_009215 CN(C)Cc1c(O)ccc2c([N+](=O)[O-])c(C)n(c3ccc(C)cc3)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C20 compound treatment 745701.0 127000.0 0.57 758427.0 140000.0 0.69 0.8925 0.9952 1338156 ChemDiv1_009216 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C21 compound treatment 786913.0 168000.0 0.75 787831.0 169000.0 0.84 1.126 0.9986 1974463 ChemDiv1_009217 Cc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C22 compound treatment 745453.0 127000.0 0.57 747550.0 129000.0 0.64 0.8536 0.9982 1974464 ChemDiv1_009218 CC(=O)c1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C(F)(F)F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C23 mock treatment 723365.0 105000.0 0.47 748373.0 130000.0 0.64 0.7866 0.9879 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 C24 mock treatment 510947.0 -108000.0 -0.48 538014.0 -80500.0 -0.4 -0.6226 -0.9956 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D01 compound treatment 611983.0 -6610.0 -0.03 596608.0 -21900.0 -0.11 -0.0976 -0.8685 1974465 ChemDiv1_009219 COc1ccc(cc1)C/2=NN(C(=O)\C2=C/c3ccc(OC)c(OC)c3OC)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D02 compound treatment 662995.0 44400.0 0.2 657999.0 39500.0 0.2 0.279 1.0 1261581 ChemDiv1_009220 Cc1cc(nc(NCc2ccccc2)n1)N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D03 compound treatment 690329.0 71700.0 0.32 703589.0 85100.0 0.42 0.5252 0.991 1974466 ChemDiv1_009221 COc1ccc(cc1CSc2nc3ccccc3o2)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D04 compound treatment 726524.0 108000.0 0.48 715092.0 96600.0 0.48 0.68 1.0 1785883 ChemDiv1_009222 COc1cc(cc(OC)c1O)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D05 compound treatment 731898.0 113000.0 0.51 739591.0 121000.0 0.6 0.7829 0.9965 1974467 ChemDiv1_009223 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)C(F)(F)F)C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D06 compound treatment 710993.0 92400.0 0.41 695429.0 76900.0 0.38 0.562 0.9992 1974468 ChemDiv1_009224 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4Br)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D07 compound treatment 729960.0 111000.0 0.5 756826.0 138000.0 0.69 0.8371 0.9878 1974469 ChemDiv1_009225 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5ccccn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D08 compound treatment 750358.0 132000.0 0.59 763051.0 145000.0 0.72 0.9235 0.9954 1537998 ChemDiv1_009226 COc1cc(cc(OC)c1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D09 compound treatment 774805.0 156000.0 0.7 793110.0 175000.0 0.87 1.1061 0.9944 1974470 ChemDiv1_009227 COc1ccc2nc(N3CCCCC3)c(/C=C/4\N(C(=O)C)C(=S)NC4=O)cc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D10 compound treatment 747238.0 129000.0 0.58 783799.0 165000.0 0.82 0.9863 0.9851 1605988 ChemDiv1_009228 COc1ccc(cc1COc2ccccn2)C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D11 compound treatment 790821.0 172000.0 0.77 811822.0 193000.0 0.96 1.2224 0.9942 1619636 ChemDiv1_009229 COc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4sc5ccccc5c4Cl)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D12 compound treatment 732826.0 114000.0 0.51 757016.0 139000.0 0.69 0.8468 0.9895 1392786 ChemDiv1_009230 COc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D13 compound treatment 694428.0 75800.0 0.34 717833.0 99400.0 0.49 0.588 0.9836 1871238 ChemDiv1_009231 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D14 compound treatment 761834.0 143000.0 0.64 807501.0 189000.0 0.94 1.1155 0.9829 1625229 ChemDiv1_009232 CCOc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D15 compound treatment 811440.0 193000.0 0.86 826637.0 208000.0 1.03 1.3395 0.9961 1974471 ChemDiv1_009233 CCSCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D16 compound treatment 741997.0 123000.0 0.55 761816.0 143000.0 0.71 0.8927 0.9923 1782128 ChemDiv1_009234 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(c3)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D17 compound treatment 796100.0 178000.0 0.79 823083.0 205000.0 1.01 1.2785 0.9927 1871392 ChemDiv1_009235 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc(cc4)[N+](=O)[O-])C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D18 compound treatment 755392.0 137000.0 0.61 758636.0 140000.0 0.69 0.9239 0.998 1600942 ChemDiv1_009236 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccc(Br)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D19 compound treatment 755907.0 137000.0 0.61 787503.0 169000.0 0.84 1.0267 0.9884 1974472 ChemDiv1_009237 [O-][N+](=O)c1ccc(cc1Sc2nc3ccccc3[nH]2)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D20 compound treatment 749361.0 131000.0 0.59 746902.0 128000.0 0.64 0.8637 0.9991 1299683 ChemDiv1_009238 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D21 compound treatment 773166.0 155000.0 0.69 793468.0 175000.0 0.87 1.1022 0.9938 1974473 ChemDiv1_009239 OCCCn1c(/C=C/2\C(=O)N(Cc3ccccc3)c4ccccc24)nc5ccccc5c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D22 compound treatment 729971.0 111000.0 0.5 749618.0 131000.0 0.65 0.8119 0.9915 1974474 ChemDiv1_009240 CN1C(=O)C(=c2sc3=NC(=C(C(c4ccc(OC(=O)c5ccco5)cc4)n3c2=O)C(=O)OCC=C)C)c6ccccc16 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D23 mock treatment 720260.0 102000.0 0.46 731842.0 113000.0 0.56 0.7189 0.9946 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 D24 mock treatment 525330.0 -93300.0 -0.42 538414.0 -80100.0 -0.4 -0.5757 -0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E01 compound treatment 626724.0 8130.0 0.04 637562.0 19100.0 0.09 0.0926 0.9139 1382464 ChemDiv1_009241 CC1CC(C)CN(C1)c2nc(nc3ccccc23)c4ccccc4O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E02 compound treatment 671237.0 52600.0 0.24 662590.0 44100.0 0.22 0.3211 0.9993 1974475 ChemDiv1_009242 COc1ccccc1/C=C(/NC(=O)c2cccc(C)c2)\C(=O)NCCc3c[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E03 compound treatment 748844.0 130000.0 0.58 746526.0 128000.0 0.63 0.8608 0.9991 1974476 ChemDiv1_009243 CN1CCN(CC1)c2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E04 compound treatment 743225.0 125000.0 0.56 734360.0 116000.0 0.57 0.8004 0.9999 1974477 ChemDiv1_009244 Cc1ccc(cc1C)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCN(CC3)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E05 compound treatment 783088.0 164000.0 0.74 753087.0 135000.0 0.67 0.9922 0.9988 1619032 ChemDiv1_009245 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E06 compound treatment 738560.0 120000.0 0.54 741785.0 123000.0 0.61 0.8116 0.9979 1664143 ChemDiv1_009246 CCOc1ccccc1C2C(C(=O)OC)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E07 compound treatment 774711.0 156000.0 0.7 800652.0 182000.0 0.9 1.1323 0.992 1738113 ChemDiv1_009247 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(OC)c(c13)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E08 compound treatment 767849.0 149000.0 0.67 769883.0 151000.0 0.75 1.0028 0.9983 1974478 ChemDiv1_009248 Clc1cc(Cl)cc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E09 compound treatment 773141.0 155000.0 0.69 806542.0 188000.0 0.93 1.1479 0.9893 1574393 ChemDiv1_009249 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccco2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E10 compound treatment 793612.0 175000.0 0.78 815596.0 197000.0 0.98 1.2444 0.994 1310386 ChemDiv1_009250 O=C(CSc1nc2CCCCc2c(c1C#N)c3cccnc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E11 compound treatment 787909.0 169000.0 0.76 822221.0 204000.0 1.01 1.2496 0.99 1718366 ChemDiv1_009251 COc1ccc(cc1OC)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E12 compound treatment 770984.0 152000.0 0.68 773328.0 155000.0 0.77 1.0248 0.9983 1330645 ChemDiv1_009252 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E13 compound treatment 783545.0 165000.0 0.74 811638.0 193000.0 0.96 1.1987 0.9918 1199301 ChemDiv1_009253 Clc1ccc(cc1)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E14 compound treatment 747115.0 129000.0 0.58 782655.0 164000.0 0.81 0.9819 0.9856 1599017 ChemDiv1_009254 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(C)cc2)C#N)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E15 compound treatment 799969.0 181000.0 0.81 848102.0 230000.0 1.14 1.3784 0.9863 1590010 ChemDiv1_009255 Fc1ccc(Cc2cnc(NC(=O)C3CCCO3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E16 compound treatment 793775.0 175000.0 0.78 804337.0 186000.0 0.92 1.2055 0.9968 1733256 ChemDiv1_009256 CC1=C(C(C(=C(N1)SCC(=O)Nc2cc(C)ccc2C)C#N)c3ccco3)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E17 compound treatment 1487067.0 868000.0 3.89 1521163.0 903000.0 4.47 5.9109 0.9976 1173606 ChemDiv1_009257 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCN(C)CC4)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E18 compound treatment 790964.0 172000.0 0.77 787105.0 169000.0 0.84 1.1363 0.9992 1452253 ChemDiv1_009258 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cc(C)ccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E19 compound treatment 795025.0 176000.0 0.79 777746.0 159000.0 0.79 1.1163 1.0 1974479 ChemDiv1_009259 CCN(CC)c1nc(nc(C)c1[N+](=O)[O-])N2CCOCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E20 compound treatment 755742.0 137000.0 0.61 780325.0 162000.0 0.8 1.001 0.9913 1300103 ChemDiv1_009260 COc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E21 compound treatment 790562.0 172000.0 0.77 807920.0 189000.0 0.94 1.2079 0.9952 1974480 ChemDiv1_009261 Cc1nc(nc(Nc2ccc(Cl)cc2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E22 compound treatment 763903.0 145000.0 0.65 778060.0 160000.0 0.79 1.0189 0.9953 1519835 ChemDiv1_009262 CCOc1ccccc1C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccccc4CC)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E23 mock treatment 743316.0 125000.0 0.56 761083.0 143000.0 0.71 0.8943 0.9932 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 E24 mock treatment 538982.0 -79600.0 -0.36 550967.0 -67500.0 -0.33 -0.4885 -0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F01 compound treatment 512263.0 -106000.0 -0.48 513441.0 -105000.0 -0.52 -0.7045 -0.999 1974481 ChemDiv1_009263 COc1cc(cc(Br)c1OCc2ccc(F)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F02 compound treatment 663054.0 44500.0 0.2 623307.0 4830.0 0.02 0.1576 0.7864 1607740 ChemDiv1_009264 Cc1cc(nc(NCc2ccccc2)n1)N3CCN(CC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F03 compound treatment 707183.0 88600.0 0.4 718116.0 99600.0 0.49 0.6294 0.9941 1121526 ChemDiv1_009265 COc1ccc(cc1CN2CCN(CC2)c3ccc(F)cc3)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F04 compound treatment 698768.0 80200.0 0.36 701523.0 83000.0 0.41 0.5446 0.9977 1974482 ChemDiv1_009266 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4cccc(OC(=O)N5CCOCC5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F05 compound treatment 805337.0 187000.0 0.84 796620.0 178000.0 0.88 1.2151 0.9996 1974483 ChemDiv1_009267 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(Br)c4)C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F06 compound treatment 720379.0 102000.0 0.46 724860.0 106000.0 0.53 0.6948 0.9974 1974484 ChemDiv1_009268 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4cccc(OC(=O)c5ccco5)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F07 compound treatment 753469.0 135000.0 0.6 764024.0 146000.0 0.72 0.9367 0.9961 1974485 ChemDiv1_009269 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F08 compound treatment 736035.0 117000.0 0.53 766391.0 148000.0 0.73 0.8898 0.9867 1192407 ChemDiv1_009270 COc1ccc(cc1COc2ccc(F)cc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F09 compound treatment 742721.0 124000.0 0.56 783475.0 165000.0 0.82 0.9708 0.9823 1974486 ChemDiv1_009271 COc1ccc2nc(N3CCOCC3)c(/C=C/4\N(C(=O)C)C(=S)NC4=O)cc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F10 compound treatment 740760.0 122000.0 0.55 722217.0 104000.0 0.51 0.7501 0.9995 1617032 ChemDiv1_009272 COc1ccc(cc1Cn2nc(C)c(Br)c2C)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F11 compound treatment 752530.0 134000.0 0.6 808116.0 190000.0 0.94 1.0882 0.9765 1413357 ChemDiv1_009273 COc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F12 compound treatment 751415.0 133000.0 0.59 749368.0 131000.0 0.65 0.8789 0.9991 1623461 ChemDiv1_009274 COc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F13 compound treatment 758744.0 140000.0 0.63 779329.0 161000.0 0.8 1.007 0.993 1293782 ChemDiv1_009275 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccc(C)cc5c4=O)C(=O)OCC6CCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F14 compound treatment 759280.0 141000.0 0.63 785388.0 167000.0 0.83 1.03 0.991 1735121 ChemDiv1_009276 CCOc1ccccc1NC(=O)C2=C(C)NC(=O)NC2c3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F15 compound treatment 760363.0 142000.0 0.63 787060.0 169000.0 0.84 1.0392 0.9908 1974487 ChemDiv1_009277 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F16 compound treatment 764073.0 145000.0 0.65 797693.0 179000.0 0.89 1.0882 0.9884 1974488 ChemDiv1_009278 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cccc(Br)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F17 compound treatment 766866.0 148000.0 0.66 817040.0 199000.0 0.98 1.1648 0.9817 1133378 ChemDiv1_009279 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccccc5c4=O)C(=O)OC6CCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F18 compound treatment 757540.0 139000.0 0.62 762051.0 144000.0 0.71 0.9427 0.9978 1584331 ChemDiv1_009280 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F19 compound treatment 773773.0 155000.0 0.69 778840.0 160000.0 0.79 1.0529 0.9978 1974489 ChemDiv1_009281 Nc1ncnc2[nH]c(Sc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F20 compound treatment 734735.0 116000.0 0.52 774730.0 156000.0 0.77 0.9149 0.9813 1691779 ChemDiv1_009282 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F21 compound treatment 769343.0 151000.0 0.67 774948.0 156000.0 0.78 1.0252 0.9976 1974490 ChemDiv1_009283 CC(=O)NC1=NN(C(=O)C)C2(S1)C(=O)N(C(=O)C)c3ccccc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F22 compound treatment 736981.0 118000.0 0.53 763487.0 145000.0 0.72 0.8827 0.9888 1263978 ChemDiv1_009284 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F23 mock treatment 698333.0 79700.0 0.36 708226.0 89700.0 0.44 0.5667 0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 F24 mock treatment 504526.0 -114000.0 -0.51 526537.0 -91900.0 -0.46 -0.6831 -0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G01 compound treatment 638862.0 20300.0 0.09 628193.0 9710.0 0.05 0.0982 0.956 1318548 ChemDiv1_009285 COc1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G02 compound treatment 689436.0 70800.0 0.32 654077.0 35600.0 0.18 0.3489 0.9616 1974491 ChemDiv1_009286 COc1ccc(/C=C(/NC(=O)c2ccco2)\C(=O)NCCc3c[nH]c4ccccc34)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G03 compound treatment 729243.0 111000.0 0.5 736148.0 118000.0 0.58 0.7624 0.9967 1533661 ChemDiv1_009287 CCCOc1ccc(cc1)c2nc(N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G04 compound treatment 742556.0 124000.0 0.55 730807.0 112000.0 0.56 0.7858 1.0 1974492 ChemDiv1_009288 Cc1ccc(cc1C)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCN(CC3)c4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G05 compound treatment 754689.0 136000.0 0.61 750796.0 132000.0 0.66 0.8942 0.9993 1685620 ChemDiv1_009289 CC(C)Sc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G06 compound treatment 732304.0 114000.0 0.51 727138.0 109000.0 0.54 0.7405 0.9996 1211297 ChemDiv1_009290 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G07 compound treatment 754890.0 136000.0 0.61 794533.0 176000.0 0.87 1.0481 0.9847 1366316 ChemDiv1_009291 CCOC(=O)c1c(C)n(C)c2cc(CN(C)C)c(O)c(c12)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G08 compound treatment 766123.0 148000.0 0.66 750428.0 132000.0 0.65 0.9292 1.0 1974493 ChemDiv1_009292 Clc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G09 compound treatment 779348.0 161000.0 0.72 806596.0 188000.0 0.93 1.1678 0.9918 1669345 ChemDiv1_009293 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2cccs2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G10 compound treatment 746318.0 128000.0 0.57 776226.0 158000.0 0.78 0.9568 0.9882 1470743 ChemDiv1_009294 CC1C(=C(NC2=C1C(=O)CC(C)(C)C2)SCC(=O)Nc3ccc(Br)cc3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G11 compound treatment 765127.0 147000.0 0.66 789230.0 171000.0 0.85 1.0619 0.9921 1636353 ChemDiv1_009295 COc1ccccc1c2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G12 compound treatment 752477.0 134000.0 0.6 752101.0 134000.0 0.66 0.8918 0.9988 1299014 ChemDiv1_009296 Cc1c(Cl)cccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G13 compound treatment 770473.0 152000.0 0.68 841357.0 223000.0 1.1 1.2614 0.9729 1146853 ChemDiv1_009297 COc1ccc(cc1OC)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G14 compound treatment 778713.0 160000.0 0.72 797146.0 179000.0 0.89 1.1326 0.9945 1383277 ChemDiv1_009298 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C(C(=O)OC)C(=O)N2)c3cc(OC)c(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G15 compound treatment 816563.0 198000.0 0.89 826432.0 208000.0 1.03 1.355 0.9972 1882627 ChemDiv1_009299 O=C1Nc2ccccc2C31Oc4ccccc4C5CC(=NN53)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G16 compound treatment 798083.0 179000.0 0.8 817857.0 199000.0 0.99 1.2665 0.9948 1612715 ChemDiv1_009300 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G17 compound treatment 2582679.0 1960000.0 8.79 2620693.0 2000000.0 9.92 13.2303 0.9982 1662053 ChemDiv1_009301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCN(C)CC4)c(=O)n2C1c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G18 compound treatment 775845.0 157000.0 0.7 792680.0 174000.0 0.86 1.1079 0.9949 1404111 ChemDiv1_009302 CCOc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(F)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G19 compound treatment 806198.0 188000.0 0.84 799963.0 181000.0 0.9 1.2295 0.9994 1974494 ChemDiv1_009303 Cc1nc(nc(NCc2ccccc2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G20 compound treatment 760585.0 142000.0 0.64 770356.0 152000.0 0.75 0.9814 0.9965 1148213 ChemDiv1_009304 Clc1cccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G21 compound treatment 768350.0 150000.0 0.67 772819.0 154000.0 0.76 1.0146 0.9979 1974495 ChemDiv1_009305 Cc1nc(nc(Nc2cccc(Cl)c2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G22 compound treatment 755528.0 137000.0 0.61 768902.0 150000.0 0.75 0.9603 0.9953 1583699 ChemDiv1_009306 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G23 mock treatment 722450.0 104000.0 0.46 766160.0 148000.0 0.73 0.846 0.976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 G24 mock treatment 549668.0 -68900.0 -0.31 558533.0 -59900.0 -0.3 -0.4282 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H01 compound treatment 606791.0 -11800.0 -0.05 585788.0 -32700.0 -0.16 -0.1519 -0.8916 1974496 ChemDiv1_009307 COc1cc(ccc1OCc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H02 compound treatment 615772.0 -2830.0 -0.01 614137.0 -4340.0 -0.02 -0.0242 -0.9679 1610447 ChemDiv1_009308 Cc1ccc(Nc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H03 compound treatment 696634.0 78000.0 0.35 682583.0 64100.0 0.32 0.4715 0.9989 1328250 ChemDiv1_009309 COc1ccc(cc1CN2CCCc3ccccc23)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H04 compound treatment 690793.0 72200.0 0.32 682776.0 64300.0 0.32 0.4537 1.0 1785880 ChemDiv1_009310 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccc(OC(=O)N5CCOCC5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H05 compound treatment 733819.0 115000.0 0.52 729077.0 111000.0 0.55 0.7521 0.9995 1974497 ChemDiv1_009311 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H06 compound treatment 685153.0 66600.0 0.3 678340.0 59900.0 0.3 0.4203 1.0 1974498 ChemDiv1_009312 CCCOc1ccc(cc1)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H07 compound treatment 748019.0 129000.0 0.58 726410.0 108000.0 0.53 0.7877 0.9992 1299411 ChemDiv1_009313 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4cccc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H08 compound treatment 742224.0 124000.0 0.55 747225.0 129000.0 0.64 0.8423 0.9975 1399300 ChemDiv1_009314 COc1ccc(cc1COc2ccccc2F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H09 compound treatment 756731.0 138000.0 0.62 775228.0 157000.0 0.78 0.9863 0.9936 1369453 ChemDiv1_009315 CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3cc4cc(OC)ccc4oc3=O)cc2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H10 compound treatment 746560.0 128000.0 0.57 753134.0 135000.0 0.67 0.8767 0.9971 1460439 ChemDiv1_009316 COc1ccc(cc1COc2ccc(NC(=O)C)cc2)C3Nc4ccccc4C(=O)N3Cc5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H11 compound treatment 717491.0 98900.0 0.44 749064.0 131000.0 0.65 0.7704 0.9829 1974499 ChemDiv1_009317 CCOCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H12 compound treatment 760753.0 142000.0 0.64 737949.0 119000.0 0.59 0.8684 0.9993 1128797 ChemDiv1_009318 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H13 compound treatment 751505.0 133000.0 0.59 740186.0 122000.0 0.6 0.847 1.0 1974500 ChemDiv1_009319 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OCC)c3)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H14 compound treatment 762431.0 144000.0 0.64 783150.0 165000.0 0.82 1.0321 0.9931 1974501 ChemDiv1_009320 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccc(Br)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H15 compound treatment 764333.0 146000.0 0.65 782433.0 164000.0 0.81 1.0356 0.9941 1974502 ChemDiv1_009321 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c3ccc(F)c(Br)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H16 compound treatment 761660.0 143000.0 0.64 716814.0 98300.0 0.49 0.7973 0.9909 1179973 ChemDiv1_009322 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Br)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H17 compound treatment 761792.0 143000.0 0.64 799882.0 181000.0 0.9 1.0887 0.9863 1206290 ChemDiv1_009323 CC(C)COC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H18 compound treatment 727253.0 109000.0 0.49 748344.0 130000.0 0.64 0.7988 0.9905 1736513 ChemDiv1_009324 CC1=C(C(NC(=O)N1)c2ccc(O)cc2)C(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H19 compound treatment 763233.0 145000.0 0.65 779506.0 161000.0 0.8 1.0219 0.9946 1349898 ChemDiv1_009325 CCn1c(SCC(=O)O)nc2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H20 compound treatment 759185.0 141000.0 0.63 766435.0 148000.0 0.73 0.9633 0.9971 1974503 ChemDiv1_009326 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H21 compound treatment 748925.0 130000.0 0.58 744326.0 126000.0 0.62 0.8533 0.9995 1974504 ChemDiv1_009327 CCCCCOC(=O)CSc1nnc(o1)c2cc(OC)c(OC)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H22 compound treatment 725994.0 107000.0 0.48 723859.0 105000.0 0.52 0.7091 0.9992 1552357 ChemDiv1_009328 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H23 mock treatment 709315.0 90700.0 0.41 708091.0 89600.0 0.44 0.601 0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 H24 mock treatment 516284.0 -102000.0 -0.46 560630.0 -57900.0 -0.29 -0.5265 -0.9745 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I01 compound treatment 619882.0 1280.0 0.01 602152.0 -16300.0 -0.08 -0.0531 -0.6552 1457150 ChemDiv1_009329 COc1ccccc1Nc2nc(nc3ccccc23)c4ccccc4O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I02 compound treatment 660539.0 41900.0 0.19 645738.0 27300.0 0.14 0.2282 0.9869 1974505 ChemDiv1_009330 Cc1ccc(cc1)C(=O)N/C(=C\c2cccnc2)/C(=O)NCCc3c[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I03 compound treatment 710172.0 91600.0 0.41 696171.0 77700.0 0.38 0.562 0.9995 1974506 ChemDiv1_009331 Brc1ccc(Nc2nc(nc3ccccc23)c4cccnc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I04 compound treatment 713717.0 95100.0 0.43 713516.0 95000.0 0.47 0.634 0.9987 1974507 ChemDiv1_009332 Cc1ccc(cc1C)C(=O)N/C(=C\c2cccs2)/C(=O)N3CCN(CC3)c4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I05 compound treatment 741095.0 122000.0 0.55 750306.0 132000.0 0.65 0.8495 0.9962 1244909 ChemDiv1_009333 CC(=C)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C5CCOC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I06 compound treatment 699812.0 81200.0 0.36 717636.0 99200.0 0.49 0.6044 0.989 1628687 ChemDiv1_009334 CCOC(=O)C1=C(C)NC(=C(C#N)C1CC(C)C)SCC(=O)c2ccc(Cl)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I07 compound treatment 755801.0 137000.0 0.61 770954.0 152000.0 0.76 0.9684 0.9947 1646675 ChemDiv1_009335 CCOC(=O)c1c(CNc2ccccc2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I08 compound treatment 768332.0 150000.0 0.67 762611.0 144000.0 0.71 0.9788 0.9995 1974508 ChemDiv1_009336 O=C(CSC1=C(C#N)C(CC(=O)N1)c2cccs2)Nc3ccc4ccccc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I09 compound treatment 761949.0 143000.0 0.64 788398.0 170000.0 0.84 1.0489 0.991 1974509 ChemDiv1_009337 Brc1ccc(cc1)c2noc(Cn3cc(C=O)c4ccccc34)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I10 compound treatment 760178.0 142000.0 0.63 774065.0 156000.0 0.77 0.9931 0.9953 1646134 ChemDiv1_009338 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cc(OC)c(Cl)cc2OC)C#N)c3ccccc3OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I11 compound treatment 760987.0 142000.0 0.64 791938.0 173000.0 0.86 1.0583 0.9892 1974510 ChemDiv1_009339 CN(C)CCCNc1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I12 compound treatment 745966.0 127000.0 0.57 741187.0 123000.0 0.61 0.833 0.9995 1717483 ChemDiv1_009340 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(OC)cc2)C#N)c3ccc(cc3)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I13 compound treatment 757201.0 139000.0 0.62 789133.0 171000.0 0.85 1.0365 0.9884 1974511 ChemDiv1_009341 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccccc3nc2N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I14 compound treatment 761342.0 143000.0 0.64 803145.0 185000.0 0.91 1.0987 0.9846 1974512 ChemDiv1_009342 COc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I15 compound treatment 817365.0 199000.0 0.89 864641.0 246000.0 1.22 1.4914 0.988 1974513 ChemDiv1_009343 O=C1N(Cc2ccccc2)c3ccccc3C41Oc5ccccc5C6CC(=NN64)c7ccco7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I16 compound treatment 775664.0 157000.0 0.7 818551.0 200000.0 0.99 1.198 0.9859 1974514 ChemDiv1_009344 COC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(c1C#N)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I17 compound treatment 780932.0 162000.0 0.73 806272.0 188000.0 0.93 1.1716 0.9925 1974515 ChemDiv1_009345 O=C(CN1C(=O)c2ccccc2C1=O)OCCOCCNC3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I18 compound treatment 768412.0 150000.0 0.67 781330.0 163000.0 0.81 1.0446 0.9958 1472479 ChemDiv1_009346 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(OC)c2)C#N)c3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I19 compound treatment 775702.0 157000.0 0.7 775702.0 157000.0 0.78 1.048 0.9987 1974516 ChemDiv1_009347 Cc1nc(nc(NC2CCCCC2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I20 compound treatment 773134.0 155000.0 0.69 773798.0 155000.0 0.77 1.0332 0.9986 1463596 ChemDiv1_009348 COc1cc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4)c(OC)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I21 compound treatment 765752.0 147000.0 0.66 789489.0 171000.0 0.85 1.0648 0.9923 1974517 ChemDiv1_009349 Cc1nc(nc(Nc2cccc(F)c2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I22 compound treatment 760801.0 142000.0 0.64 744303.0 126000.0 0.62 0.8909 0.9999 1220634 ChemDiv1_009350 COc1ccc(cc1OC)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I23 mock treatment 721515.0 103000.0 0.46 745811.0 127000.0 0.63 0.7718 0.9881 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 I24 mock treatment 545562.0 -73000.0 -0.33 559894.0 -58600.0 -0.29 -0.4364 -0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J01 compound treatment 623851.0 5250.0 0.02 588927.0 -29600.0 -0.15 -0.0869 -0.586 1974518 ChemDiv1_009351 COC(=O)c1ccc(COc2ccc(cc2OC)C3C(=C(N)Oc4[nH]nc(C)c34)C#N)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J02 compound treatment 686404.0 67800.0 0.3 654779.0 36300.0 0.18 0.3418 0.9688 1135585 ChemDiv1_009352 CCOC(=O)c1ccc(Nc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J03 compound treatment 706650.0 88100.0 0.39 697535.0 79100.0 0.39 0.5556 1.0 1575659 ChemDiv1_009353 COc1ccc(cc1Cn2nnc3ccccc23)C4C(=C(N)Oc5[nH]nc(C)c45)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J04 compound treatment 700579.0 82000.0 0.37 673576.0 55100.0 0.27 0.4525 0.9894 1974519 ChemDiv1_009354 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J05 compound treatment 757444.0 139000.0 0.62 731349.0 113000.0 0.56 0.8348 0.9986 1974520 ChemDiv1_009355 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J06 compound treatment 694713.0 76100.0 0.34 668058.0 49600.0 0.25 0.4146 0.9871 1974521 ChemDiv1_009356 COc1ccc(C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J07 compound treatment 717230.0 98600.0 0.44 737149.0 119000.0 0.59 0.7279 0.99 1974522 ChemDiv1_009357 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C3)c4ccccc4)C(=O)Nc5cccc(C)n5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J08 compound treatment 739908.0 121000.0 0.54 735772.0 117000.0 0.58 0.7948 0.9994 1974523 ChemDiv1_009358 COc1ccc(cc1CN2C(=O)c3ccccc3C2=O)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J09 compound treatment 768168.0 150000.0 0.67 753369.0 135000.0 0.67 0.9459 1.0 1690454 ChemDiv1_009359 COc1ccccc1N2CCN(CC2)C(=O)c3cc4cccc(CC=C)c4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J10 compound treatment 768369.0 150000.0 0.67 756643.0 138000.0 0.68 0.958 0.9999 1401248 ChemDiv1_009360 COc1cccc(OCc2cc(ccc2OC)C3Nc4ccccc4C(=O)N3Cc5ccco5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J11 compound treatment 730115.0 112000.0 0.5 714896.0 96400.0 0.48 0.6907 0.9998 1871365 ChemDiv1_009361 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J12 compound treatment 748379.0 130000.0 0.58 758302.0 140000.0 0.69 0.9006 0.9962 1431253 ChemDiv1_009362 CC(C)c1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J13 compound treatment 744154.0 126000.0 0.56 709571.0 91100.0 0.45 0.7165 0.9941 1974524 ChemDiv1_009363 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCSCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J14 compound treatment 764280.0 146000.0 0.65 747092.0 129000.0 0.64 0.9116 0.9999 1974525 ChemDiv1_009364 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J15 compound treatment 741648.0 123000.0 0.55 784182.0 166000.0 0.82 0.9699 0.9812 1709195 ChemDiv1_009365 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J16 compound treatment 763656.0 145000.0 0.65 747411.0 129000.0 0.64 0.9108 1.0 1974526 ChemDiv1_009366 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccccc3Cl)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J17 compound treatment 767928.0 149000.0 0.67 765832.0 147000.0 0.73 0.9888 0.999 1974527 ChemDiv1_009367 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(O)c(OC)c3)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J18 compound treatment 765042.0 146000.0 0.66 761967.0 143000.0 0.71 0.9662 0.9992 1974528 ChemDiv1_009368 CC1=C(C(NC(=O)N1)c2ccc(Br)cc2)C(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J19 compound treatment 2286499.0 1670000.0 7.47 2425177.0 1810000.0 8.95 11.608 0.9959 1974529 ChemDiv1_009369 O=C1/C(=C/c2ccc(o2)c3ccc(cc3)S(=O)(=O)Nc4nccs4)/Sc5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J20 compound treatment 734757.0 116000.0 0.52 728450.0 110000.0 0.54 0.7529 0.9997 1641590 ChemDiv1_009370 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)Nc3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J21 compound treatment 768155.0 150000.0 0.67 743677.0 125000.0 0.62 0.9119 0.9993 1325797 ChemDiv1_009371 Cc1ccc(cc1)n2ncc3c(Nc4ccc(Br)cc4)ncnc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J22 compound treatment 732215.0 114000.0 0.51 720653.0 102000.0 0.51 0.7175 1.0 1544497 ChemDiv1_009372 Cc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J23 mock treatment 732804.0 114000.0 0.51 739902.0 121000.0 0.6 0.7868 0.9967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 J24 mock treatment 523827.0 -94800.0 -0.42 531005.0 -87500.0 -0.43 -0.6064 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K01 compound treatment 593985.0 -24600.0 -0.11 610180.0 -8300.0 -0.04 -0.107 -0.9097 1227490 ChemDiv1_009373 COc1ccc(Nc2nc(nc3ccccc23)c4ccccc4O)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K02 compound treatment 667222.0 48600.0 0.22 654983.0 36500.0 0.18 0.2818 0.9958 1974530 ChemDiv1_009374 O=C(NCCc1c[nH]c2ccccc12)/C(=C/c3ccco3)/NC(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K03 compound treatment 697555.0 79000.0 0.35 692245.0 73800.0 0.37 0.5083 0.9999 1974531 ChemDiv1_009375 Fc1ccc(Nc2nc(nc3ccccc23)c4cccnc4)cc1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K04 compound treatment 685254.0 66700.0 0.3 680695.0 62200.0 0.31 0.4289 0.9999 1974532 ChemDiv1_009376 Cc1ccc(cc1C)C(=O)N/C(=C/c2cccs2)/C(=O)NCCc3c[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K05 compound treatment 735228.0 117000.0 0.52 736766.0 118000.0 0.59 0.7835 0.9983 1737091 ChemDiv1_009377 NC(=O)CSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1CCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K06 compound treatment 727417.0 109000.0 0.49 720341.0 102000.0 0.5 0.7012 0.9998 1974533 ChemDiv1_009378 Cc1ccsc1C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K07 compound treatment 742819.0 124000.0 0.56 758057.0 140000.0 0.69 0.8821 0.9942 1440960 ChemDiv1_009379 CCOC(=O)c1c(CNc2cccc(Cl)c2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K08 compound treatment 721084.0 102000.0 0.46 722774.0 104000.0 0.52 0.6897 0.9982 1974534 ChemDiv1_009380 Brc1cccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K09 compound treatment 750731.0 132000.0 0.59 768663.0 150000.0 0.74 0.9443 0.9935 1701491 ChemDiv1_009381 Clc1cc(NC(=O)c2ccc3OCCOc3c2)ccc1N4CCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K10 compound treatment 744785.0 126000.0 0.56 741243.0 123000.0 0.61 0.8294 0.9993 1974535 ChemDiv1_009382 COCCOC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3cccc(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K11 compound treatment 740930.0 122000.0 0.55 755327.0 137000.0 0.68 0.8666 0.9944 1974536 ChemDiv1_009383 CCN(CC)CCCNc1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K12 compound treatment 737707.0 119000.0 0.53 752412.0 134000.0 0.66 0.8462 0.9941 1367681 ChemDiv1_009384 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccccc2C)C#N)c3ccc(cc3)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K13 compound treatment 735997.0 117000.0 0.53 737235.0 119000.0 0.59 0.7876 0.9984 1974537 ChemDiv1_009385 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3ccccc3nc2N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K14 compound treatment 726509.0 108000.0 0.48 759681.0 141000.0 0.7 0.8362 0.9837 1303771 ChemDiv1_009386 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(OC)cc2)C#N)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K15 compound treatment 755487.0 137000.0 0.61 794364.0 176000.0 0.87 1.0494 0.9852 1974538 ChemDiv1_009387 [O-][N+](=O)c1ccc(cc1n2nc(c3ccc(F)cc3)c4ccccc4c2=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K16 compound treatment 744435.0 126000.0 0.56 785676.0 167000.0 0.83 0.984 0.9824 1974539 ChemDiv1_009388 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K17 compound treatment 768387.0 150000.0 0.67 801104.0 183000.0 0.9 1.1138 0.9891 1974540 ChemDiv1_009389 Clc1ccc(OCC(=O)OCCCNC2=NS(=O)(=O)c3ccccc23)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K18 compound treatment 718522.0 99900.0 0.45 757676.0 139000.0 0.69 0.8039 0.978 1974541 ChemDiv1_009390 CC(=O)c1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K19 compound treatment 758904.0 140000.0 0.63 741956.0 123000.0 0.61 0.8766 0.9999 1974542 ChemDiv1_009391 Cc1nc(nc(N2CCCCC2)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K20 compound treatment 744050.0 125000.0 0.56 776394.0 158000.0 0.78 0.9502 0.9868 1653193 ChemDiv1_009392 Cc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K21 compound treatment 777533.0 159000.0 0.71 765321.0 147000.0 0.73 1.0174 0.9999 1974543 ChemDiv1_009393 Cc1nc(nc(Nc2ccc(F)cc2F)c1[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K22 compound treatment 738158.0 120000.0 0.54 734953.0 116000.0 0.58 0.7864 0.9993 1458187 ChemDiv1_009394 Cc1ccc(o1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4c(C)cc(C)cc4C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K23 mock treatment 730624.0 112000.0 0.5 733016.0 115000.0 0.57 0.7558 0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 K24 mock treatment 529690.0 -88900.0 -0.4 562099.0 -56400.0 -0.28 -0.4789 -0.985 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L01 compound treatment 617400.0 -1200.0 -0.01 584712.0 -33800.0 -0.17 -0.1221 -0.7294 1607435 ChemDiv1_009395 CCOc1cc(ccc1OCc2cccc(F)c2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L02 compound treatment 728395.0 110000.0 0.49 682646.0 64200.0 0.32 0.5723 0.9778 1508513 ChemDiv1_009396 COC(=O)c1ccc(Oc2cc(C)nc(NCc3ccccc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L03 compound treatment 709967.0 91400.0 0.41 668248.0 49800.0 0.25 0.4635 0.9706 1606464 ChemDiv1_009397 COc1ccc(cc1COc2ccccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L04 compound treatment 697586.0 79000.0 0.35 661245.0 42800.0 0.21 0.3998 0.97 1974544 ChemDiv1_009398 NC1=C(C#N)C2(C(=O)Nc3ccc(F)cc32)c4c(n[nH]c4O1)c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L05 compound treatment 731189.0 113000.0 0.5 692797.0 74300.0 0.37 0.6167 0.9881 1974545 ChemDiv1_009399 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cc(ccc4C)[N+](=O)[O-])C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L06 compound treatment 712531.0 93900.0 0.42 677997.0 59500.0 0.29 0.5058 0.9849 1974546 ChemDiv1_009400 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccccc5C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L07 compound treatment 718367.0 99800.0 0.45 707785.0 89300.0 0.44 0.6286 1.0 1974547 ChemDiv1_009401 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L08 compound treatment 720389.0 102000.0 0.46 697858.0 79400.0 0.39 0.6002 0.9973 1591556 ChemDiv1_009402 COc1ccc(cc1CN2CCOCC2)C3Nc4ccccc4C(=O)N3c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L09 compound treatment 742087.0 123000.0 0.55 733623.0 115000.0 0.57 0.7942 0.9999 1175761 ChemDiv1_009403 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)sc(C)c1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L10 compound treatment 804854.0 186000.0 0.83 815914.0 197000.0 0.98 1.2811 0.9968 1974548 ChemDiv1_009404 OC(=O)c1cc(O)ccc1NC(=O)c2cccc(c2)N3C(=O)c4cccc5c(ccc(C3=O)c45)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L11 compound treatment 721607.0 103000.0 0.46 739482.0 121000.0 0.6 0.7499 0.9916 1974549 ChemDiv1_009405 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccccc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L12 compound treatment 745349.0 127000.0 0.57 736918.0 118000.0 0.59 0.8161 0.9999 1567959 ChemDiv1_009406 CC(C)c1ccc(cc1)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L13 compound treatment 681960.0 63400.0 0.28 649621.0 31100.0 0.15 0.3096 0.959 1974550 ChemDiv1_009407 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L14 compound treatment 729585.0 111000.0 0.5 750206.0 132000.0 0.65 0.8127 0.9909 1242920 ChemDiv1_009408 CC1=C(C(NC(=O)N1)c2ccc(Cl)cc2)C(=O)Nc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L15 compound treatment 749856.0 131000.0 0.59 742510.0 124000.0 0.61 0.8499 0.9998 1580637 ChemDiv1_009409 CCOc1cc(ccc1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L16 compound treatment 760160.0 142000.0 0.63 758409.0 140000.0 0.69 0.9382 0.999 1434701 ChemDiv1_009410 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)c(OC)c(OC)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L17 compound treatment 752148.0 134000.0 0.6 725454.0 107000.0 0.53 0.7974 0.9982 1974551 ChemDiv1_009411 COCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L18 compound treatment 743082.0 124000.0 0.56 711250.0 92800.0 0.46 0.719 0.9954 1190558 ChemDiv1_009412 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3cccc(Cl)c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L19 compound treatment 704822.0 86200.0 0.39 743208.0 125000.0 0.62 0.7098 0.9743 1974552 ChemDiv1_009413 CC/1=NN(C(=O)\C1=C\c2cccc(OC(=O)c3cccs3)c2)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L20 compound treatment 735514.0 117000.0 0.52 731443.0 113000.0 0.56 0.7658 0.9994 1974553 ChemDiv1_009414 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L21 compound treatment 760976.0 142000.0 0.64 737989.0 120000.0 0.59 0.8693 0.9993 1494030 ChemDiv1_009415 Cc1ccc(cc1)n2ncc3c(Nc4ccc(cc4)S(=O)(=O)N)ncnc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L22 compound treatment 723816.0 105000.0 0.47 697370.0 78900.0 0.39 0.6094 0.9957 1682880 ChemDiv1_009416 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L23 mock treatment 732393.0 114000.0 0.51 724892.0 106000.0 0.53 0.7329 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 L24 mock treatment 506662.0 -112000.0 -0.5 544696.0 -73800.0 -0.37 -0.6128 -0.988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M01 compound treatment 625554.0 6960.0 0.03 612528.0 -5950.0 -0.03 0.0012 0.0272 1523724 ChemDiv1_009417 COc1ccc(OC)c(Nc2nc(nc3ccccc23)c4ccccc4O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M02 compound treatment 672923.0 54300.0 0.24 642017.0 23500.0 0.12 0.2544 0.9433 1974554 ChemDiv1_009418 CCOC(=O)N1CCN(CC1)C(=O)/C(=C\c2cccs2)/NC(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M03 compound treatment 717006.0 98400.0 0.44 692141.0 73700.0 0.36 0.5695 0.9956 1974555 ChemDiv1_009419 Cc1cccc(c1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M04 compound treatment 702411.0 83800.0 0.38 680935.0 62500.0 0.31 0.4841 0.9954 1974556 ChemDiv1_009420 COc1ccccc1N2CCN(CC2)C(=O)/C(=C/c3cccnc3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M05 compound treatment 690502.0 71900.0 0.32 715511.0 97000.0 0.48 0.5675 0.981 1502874 ChemDiv1_009421 CCOC(=O)c1c(Cn2ccnc2C)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M06 compound treatment 693953.0 75400.0 0.34 707459.0 89000.0 0.44 0.5502 0.9913 1944831 ChemDiv1_009422 Brc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccs3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M07 compound treatment 728824.0 110000.0 0.49 730656.0 112000.0 0.56 0.7418 0.9982 1703897 ChemDiv1_009423 CCOC(=O)c1c(CN(CC)CC)n(c2ccccc2)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M08 compound treatment 729281.0 111000.0 0.5 713163.0 94700.0 0.47 0.682 0.9996 1974557 ChemDiv1_009424 O=C(CSC1=C(C#N)C(CC(=O)N1)c2cccs2)Nc3nccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M09 compound treatment 711559.0 93000.0 0.42 722158.0 104000.0 0.51 0.6574 0.9946 1974558 ChemDiv1_009425 [O-][N+](=O)c1c(Sc2ncnc3ccccc23)ccc4nsnc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M10 compound treatment 698429.0 79800.0 0.36 719588.0 101000.0 0.5 0.6069 0.9863 1974559 ChemDiv1_009426 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2cccc(c2)C(=O)C)C#N)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M11 compound treatment 749146.0 131000.0 0.58 749804.0 131000.0 0.65 0.8732 0.9986 1398306 ChemDiv1_009427 Cc1c(NC(=O)CSc2nc3ccccc3[nH]2)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M12 compound treatment 720631.0 102000.0 0.46 720707.0 102000.0 0.51 0.681 0.9987 1974560 ChemDiv1_009428 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(cc2)C(=O)C)C#N)c3ccc(cc3)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M13 compound treatment 726990.0 108000.0 0.49 738418.0 120000.0 0.59 0.7632 0.9949 1974561 ChemDiv1_009429 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3cc(C)ccc3nc2N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M14 compound treatment 741973.0 123000.0 0.55 738119.0 120000.0 0.59 0.8096 0.9994 1974562 ChemDiv1_009430 COC(=O)C1=C(C)NC(=C(C#N)C1c2ccccc2Cl)SCC(=O)Nc3ccc(cc3)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M15 compound treatment 723474.0 105000.0 0.47 776513.0 158000.0 0.78 0.8855 0.9701 1974563 ChemDiv1_009431 Cc1ccc(cc1C)c2nn(c3cc(ccc3N4CCCC4)[N+](=O)[O-])c(=O)c5ccccc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M16 compound treatment 719707.0 101000.0 0.45 751491.0 133000.0 0.66 0.786 0.9832 1974564 ChemDiv1_009432 CCc1ccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccc(cc3)C(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M17 compound treatment 741535.0 123000.0 0.55 739409.0 121000.0 0.6 0.8127 0.9991 1974565 ChemDiv1_009433 COc1ccc(cc1)C(=O)OCCN2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M18 compound treatment 748251.0 130000.0 0.58 683894.0 65400.0 0.32 0.6395 0.9621 1189801 ChemDiv1_009434 CC1=C(C(C(=C(N1)SCC(=O)Nc2cccc(C)c2C)C#N)c3ccco3)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M19 compound treatment 758046.0 139000.0 0.62 771163.0 153000.0 0.76 0.9762 0.9955 1974566 ChemDiv1_009435 Cc1nc(nc(N2CCN(CC2)c3ccccc3)c1[N+](=O)[O-])N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M20 compound treatment 718303.0 99700.0 0.45 712879.0 94400.0 0.47 0.6463 0.9997 1717619 ChemDiv1_009436 Clc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M21 compound treatment 755351.0 137000.0 0.61 743219.0 125000.0 0.62 0.8698 1.0 1974567 ChemDiv1_009437 Cc1cc(C)n(n1)c2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M22 compound treatment 735901.0 117000.0 0.53 722558.0 104000.0 0.52 0.7359 1.0 1974568 ChemDiv1_009438 Cc1ccccc1NC(=O)c2c(C)nc(SCC(=O)N)c(C#N)c2c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M23 mock treatment 706536.0 87900.0 0.39 700712.0 82200.0 0.41 0.5664 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 M24 mock treatment 565049.0 -53500.0 -0.24 418995.0 -199000.0 -0.99 -0.8683 -0.8539 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N01 compound treatment 624938.0 6340.0 0.03 585709.0 -32800.0 -0.16 -0.0947 -0.5748 1301065 ChemDiv1_009439 CCOc1cc(ccc1OCc2ccc(Cl)cc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N02 compound treatment 655415.0 36800.0 0.16 617443.0 -1040.0 -0.01 0.1129 0.6847 1647181 ChemDiv1_009440 Cc1cc(Nc2cccc(F)c2)nc(n1)N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N03 compound treatment 694143.0 75500.0 0.34 654530.0 36000.0 0.18 0.3654 0.9555 1974569 ChemDiv1_009441 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4Cl)[N+](=O)[O-])C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N04 compound treatment 687799.0 69200.0 0.31 643451.0 25000.0 0.12 0.3065 0.9189 1785879 ChemDiv1_009442 NC1=C(C#N)C(c2c(n[nH]c2O1)c3cccc(c3)[N+](=O)[O-])c4ccccc4OC(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N05 compound treatment 710825.0 92200.0 0.41 674886.0 56400.0 0.28 0.4895 0.9819 1974570 ChemDiv1_009443 Cc1cc(C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4C(F)(F)F)C#N)c(C)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N06 compound treatment 665052.0 46500.0 0.21 640397.0 21900.0 0.11 0.2238 0.9541 1974571 ChemDiv1_009444 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccc4OCOc4c3)c5ccc(F)c(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N07 compound treatment 728995.0 110000.0 0.49 677602.0 59100.0 0.29 0.5565 0.9688 1409415 ChemDiv1_009445 CCSc1sc(CC)cc1C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)Nc4ccc(C)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N08 compound treatment 717102.0 98500.0 0.44 694013.0 75500.0 0.37 0.5764 0.9967 1673549 ChemDiv1_009446 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(Cn5nnc6ccccc56)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N09 compound treatment 753181.0 135000.0 0.6 725154.0 107000.0 0.53 0.7997 0.9979 1974572 ChemDiv1_009447 CC(C)c1cc(C)ccc1OCCSc2nc3c(N)ncnc3[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N10 compound treatment 687971.0 69400.0 0.31 684923.0 66400.0 0.33 0.4523 0.9996 1119253 ChemDiv1_009448 C(Nc1nc(Nc2ccc3OCOc3c2)nc(n1)N4CCOCC4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N11 compound treatment 724044.0 105000.0 0.47 714860.0 96400.0 0.48 0.6714 1.0 1400043 ChemDiv1_009449 CC(C)OC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N12 compound treatment 719305.0 101000.0 0.45 676713.0 58200.0 0.29 0.5227 0.9767 1974573 ChemDiv1_009450 CC1=C(C(NC(=O)N1)c2ccc(F)cc2)C(=O)Nc3ccc(C)c(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N13 compound treatment 725771.0 107000.0 0.48 719976.0 101000.0 0.5 0.6948 0.9997 1152030 ChemDiv1_009451 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N14 compound treatment 723968.0 105000.0 0.47 698612.0 80100.0 0.4 0.6142 0.9963 1263865 ChemDiv1_009452 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N15 compound treatment 743397.0 125000.0 0.56 698000.0 79500.0 0.39 0.6736 0.9854 1974574 ChemDiv1_009453 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N16 compound treatment 732743.0 114000.0 0.51 700274.0 81800.0 0.41 0.6478 0.9934 1610222 ChemDiv1_009454 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Cl)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N17 compound treatment 738091.0 119000.0 0.53 723881.0 105000.0 0.52 0.7474 0.9999 1297670 ChemDiv1_009455 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N18 compound treatment 735795.0 117000.0 0.52 698910.0 80400.0 0.4 0.6527 0.9908 1340012 ChemDiv1_009456 COc1ccc(OC)c(c1)C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N19 compound treatment 778990.0 160000.0 0.72 761468.0 143000.0 0.71 1.0086 1.0 1974575 ChemDiv1_009457 COc1ccc(cc1[N+](=O)[O-])C(=O)Nc2cc(ccc2Cl)c3nc4cc(ccc4o3)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N20 compound treatment 732031.0 113000.0 0.51 703373.0 84900.0 0.42 0.6564 0.9956 1974576 ChemDiv1_009458 CCCN1C(=O)C(=c2sc3=NC(=C(C(c4ccc(OC(=O)c5ccco5)cc4)n3c2=O)C(=O)OCC)C)c6ccccc16 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N21 compound treatment 735279.0 117000.0 0.52 710517.0 92000.0 0.46 0.6917 0.9977 1786181 ChemDiv1_009459 COc1ccc(cc1Cn2cc(cn2)[N+](=O)[O-])C3Nc4ccccc4C(=O)N3Cc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N22 compound treatment 707930.0 89300.0 0.4 688914.0 70400.0 0.35 0.5295 0.9977 1412099 ChemDiv1_009460 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N23 mock treatment 708940.0 90300.0 0.4 690097.0 71600.0 0.35 0.5368 0.9979 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 N24 mock treatment 457259.0 -161000.0 -0.72 251493.0 -367000.0 -1.82 -1.7962 -0.9182 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O01 compound treatment 616945.0 -1650.0 -0.01 588123.0 -30400.0 -0.15 -0.1116 -0.741 1322048 ChemDiv1_009461 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O02 compound treatment 633028.0 14400.0 0.06 603380.0 -15100.0 -0.07 -0.0072 -0.0731 1974577 ChemDiv1_009462 OCCN1CCN(CC1)C(=O)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O03 compound treatment 649804.0 31200.0 0.14 620473.0 1990.0 0.01 0.1058 0.7552 1592862 ChemDiv1_009463 COc1ccc(cc1)n2c(=O)c3c(-c4ccccc4CC53CCCCC5)n6c(SCC(=O)N)nnc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O04 compound treatment 662167.0 43600.0 0.2 629858.0 11400.0 0.06 0.1778 0.8756 1974578 ChemDiv1_009464 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O05 compound treatment 681701.0 63100.0 0.28 660820.0 42300.0 0.21 0.348 0.9893 1424478 ChemDiv1_009465 CCOC(=O)c1c(CNc2ccncc2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O06 compound treatment 670999.0 52400.0 0.23 631383.0 12900.0 0.06 0.2111 0.8681 1695149 ChemDiv1_009466 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O07 compound treatment 692911.0 74300.0 0.33 667509.0 49000.0 0.24 0.407 0.9881 1156765 ChemDiv1_009467 CCOC(=O)c1c(CN2CCC(C)CC2)n(c3ccccc3)c4cc(Br)c(OC(=O)C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O08 compound treatment 726289.0 108000.0 0.48 684952.0 66500.0 0.33 0.5737 0.9827 1271182 ChemDiv1_009468 Cc1ccc(NC(=O)c2sc3nc4CCCCc4c(c5ccco5)c3c2N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O09 compound treatment 696508.0 77900.0 0.35 664590.0 46100.0 0.23 0.4081 0.9789 1634748 ChemDiv1_009469 Cc1nc2ccccc2c3nc(NC(=O)Cc4ccccc4)nn13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O10 compound treatment 669069.0 50500.0 0.23 655651.0 37200.0 0.18 0.29 0.9948 1322509 ChemDiv1_009470 Cc1ccc(C)c(NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4cccs4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O11 compound treatment 769681.0 151000.0 0.68 762003.0 144000.0 0.71 0.981 0.9997 1544705 ChemDiv1_009471 CCOC(=O)c1sc(NC(=O)CSc2nc3ccccc3[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O12 compound treatment 671537.0 52900.0 0.24 666822.0 48300.0 0.24 0.3369 1.0 1359590 ChemDiv1_009472 CCOc1ccc(cc1)C2C(=C(NC3=C2C(=O)CCC3)SCC(=O)Nc4ccc(NC(=O)C)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O13 compound treatment 698930.0 80300.0 0.36 696684.0 78200.0 0.39 0.5282 0.9993 1974579 ChemDiv1_009473 CC(=O)N/1C(=S)NC(=O)\C1=C\c2cc3cc(C)ccc3nc2N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O14 compound treatment 654135.0 35500.0 0.16 691506.0 73000.0 0.36 0.3683 0.9319 1974580 ChemDiv1_009474 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(F)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O15 compound treatment 716452.0 97900.0 0.44 714383.0 95900.0 0.48 0.6457 0.9992 1706825 ChemDiv1_009475 CCOC(=O)c1c(CSc2ccccc2)n(C3CCCCC3)c4cc(Br)c(O)c(CN(C)C)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O16 compound treatment 681320.0 62700.0 0.28 695243.0 76800.0 0.38 0.4674 0.9889 1974581 ChemDiv1_009476 CC(C)c1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O17 compound treatment 693454.0 74900.0 0.34 697344.0 78900.0 0.39 0.5132 0.9971 1601011 ChemDiv1_009477 OC1(CC=C)C(=O)Nc2ccccc21 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O18 compound treatment 660575.0 42000.0 0.19 663391.0 44900.0 0.22 0.2902 0.9965 1384891 ChemDiv1_009478 CC1=C(C(C(=C(N1)SCC(=O)c2ccccc2)C#N)c3ccc(Cl)cc3)C(=O)OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O19 compound treatment 714087.0 95500.0 0.43 703528.0 85000.0 0.42 0.6002 1.0 1974582 ChemDiv1_009479 CCOc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N3CCOCC3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O20 compound treatment 696222.0 77600.0 0.35 659988.0 41500.0 0.21 0.3911 0.9686 1366146 ChemDiv1_009480 CCc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccc(C)o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O21 compound treatment 710270.0 91700.0 0.41 700839.0 82400.0 0.41 0.5787 1.0 1974583 ChemDiv1_009481 Cc1nc(nc(OC2C(=O)c3ccccc3C2=O)c1[N+](=O)[O-])N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O22 compound treatment 675647.0 57000.0 0.26 677273.0 58800.0 0.29 0.3865 0.9979 1351157 ChemDiv1_009482 CC1=C(C(C(=C(N1)SCc2ccc(Cl)cc2)C#N)c3ccc(Cl)cc3)C(=O)OC(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O23 mock treatment 677831.0 59200.0 0.27 647733.0 29300.0 0.14 0.29 0.9596 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 O24 mock treatment 236345.0 -382000.0 -1.71 426564.0 -192000.0 -0.95 -1.8822 -0.9615 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P01 compound treatment 563936.0 -54700.0 -0.24 554390.0 -64100.0 -0.32 -0.3975 -0.9917 1420241 ChemDiv1_009483 CCOc1cc(ccc1OCc2ccc(o2)C(=O)OC)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P02 compound treatment 600197.0 -18400.0 -0.08 551945.0 -66500.0 -0.33 -0.2913 -0.8574 1974584 ChemDiv1_009484 Cc1ccc(cc1)n2c(=O)c3c4CC(C)(C)OCc4sc3n5c(SCC(=O)c6ccccc6)nnc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P03 compound treatment 610550.0 -8050.0 -0.04 569895.0 -48600.0 -0.24 -0.1957 -0.804 1974585 ChemDiv1_009485 Cc1sccc1C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4Cl)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P04 compound treatment 588105.0 -30500.0 -0.14 582003.0 -36500.0 -0.18 -0.2243 -0.9904 1974586 ChemDiv1_009486 COc1cc(cc(OC)c1OC)c2n[nH]c3OC(=C(C#N)C(c23)c4ccc5OCOc5c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P05 compound treatment 587450.0 -31100.0 -0.14 591274.0 -27200.0 -0.13 -0.1939 -0.9999 1974587 ChemDiv1_009487 CSc1sc(C)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P06 compound treatment 631685.0 13100.0 0.06 607341.0 -11100.0 -0.06 0.0024 0.0299 1974588 ChemDiv1_009488 COc1cc(cc(OC)c1OC(=O)C)C2C(=C(N)Oc3[nH]nc(c23)c4ccc5OCOc5c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P07 compound treatment 609998.0 -8600.0 -0.04 608759.0 -9720.0 -0.05 -0.0613 -0.9938 1974589 ChemDiv1_009489 CSc1sc(C)cc1C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P08 compound treatment 631045.0 12400.0 0.06 591694.0 -26800.0 -0.13 -0.0544 -0.3782 1410018 ChemDiv1_009490 COc1cc(cc(OC)c1OC)C2Nc3ccccc3C(=O)N2c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P09 compound treatment 634047.0 15400.0 0.07 605580.0 -12900.0 -0.06 0.0037 0.0394 1444995 ChemDiv1_009491 Nc1ncnc2[nH]c(SCC(=O)Nc3ccc(Cl)cc3)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P10 compound treatment 618738.0 141.0 0.0 600021.0 -18500.0 -0.09 -0.0642 -0.7022 1421045 ChemDiv1_009492 CCOc1nc(NCc2ccccc2)nc(NCc3cccnc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P11 compound treatment 589129.0 -29500.0 -0.13 555491.0 -63000.0 -0.31 -0.3139 -0.9266 1871229 ChemDiv1_009493 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P12 compound treatment 633099.0 14500.0 0.06 588041.0 -30400.0 -0.15 -0.0607 -0.3699 1974590 ChemDiv1_009494 CC1=C(C(NC(=O)N1)c2ccccc2)C(=O)Nc3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P13 compound treatment 600529.0 -18100.0 -0.08 545750.0 -72700.0 -0.36 -0.312 -0.8448 1871384 ChemDiv1_009495 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P14 compound treatment 617755.0 -842.0 0.0 598306.0 -20200.0 -0.1 -0.0733 -0.7333 1201246 ChemDiv1_009496 CCOc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3cc(OC)ccc3OC)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P15 compound treatment 631136.0 12500.0 0.06 586882.0 -31600.0 -0.16 -0.071 -0.427 1500676 ChemDiv1_009497 COc1ccc(C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P16 compound treatment 629287.0 10700.0 0.05 601143.0 -17300.0 -0.09 -0.0269 -0.2736 1926432 ChemDiv1_009498 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P17 compound treatment 632065.0 13500.0 0.06 599016.0 -19500.0 -0.1 -0.0256 -0.2247 1974591 ChemDiv1_009499 COCCOC(=O)C1=C(C)NC2=C(C1c3coc4ccc(C)cc4c3=O)C(=O)CC(C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P18 compound treatment 638085.0 19500.0 0.09 615289.0 -3190.0 -0.02 0.0505 0.5696 1607092 ChemDiv1_009500 COc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)Nc3ccccc3Cl)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P19 compound treatment 630554.0 12000.0 0.05 594871.0 -23600.0 -0.12 -0.0449 -0.3487 1291364 ChemDiv1_009501 COc1cc(cc(OC)c1OC)C(=O)Nc2cc(ccc2Cl)c3nc4cc(ccc4o3)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P20 compound treatment 628185.0 9590.0 0.04 570179.0 -48300.0 -0.24 -0.1388 -0.5712 1974592 ChemDiv1_009502 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC=C)c4ccccc34)c(=O)n2C1c5ccc(OC(=O)c6ccco6)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P21 compound treatment 635668.0 17100.0 0.08 618432.0 -49.1 0.0 0.0539 0.7049 1974593 ChemDiv1_009503 COc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OC)c(Cn5cc(cn5)[N+](=O)[O-])c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P22 compound treatment 610558.0 -8040.0 -0.04 589795.0 -28700.0 -0.14 -0.1259 -0.8591 1631623 ChemDiv1_009504 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P23 mock treatment 628348.0 9750.0 0.04 610814.0 -7670.0 -0.04 0.004 0.0692 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.613 P24 mock treatment 221615.0 -397000.0 -1.78 456118.0 -162000.0 -0.8 -1.8253 -0.9358 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A01 compound treatment 595140.0 -696.0 0.0 587125.0 -6190.0 -0.03 -0.0239 -0.7749 1293447 ChemDiv1_009505 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A02 compound treatment 592293.0 -3540.0 -0.02 588475.0 -4840.0 -0.02 -0.0282 -0.9798 1864033 ChemDiv1_009506 COc1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A03 compound treatment 601491.0 5660.0 0.03 591469.0 -1850.0 -0.01 0.0114 0.4241 1974594 ChemDiv1_009507 Clc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A04 compound treatment 601836.0 6000.0 0.03 580362.0 -13000.0 -0.06 -0.0264 -0.3794 1864046 ChemDiv1_009508 [O-][N+](=O)c1ccc(cc1)c2nc(NC3CCCCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A05 compound treatment 614623.0 18800.0 0.08 592148.0 -1170.0 -0.01 0.0554 0.6567 1974595 ChemDiv1_009509 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A06 compound treatment 630072.0 34200.0 0.15 619055.0 25700.0 0.13 0.1985 0.9958 1974596 ChemDiv1_009510 [O-][N+](=O)c1ccc(cc1)c2nc(NCCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A07 compound treatment 663342.0 67500.0 0.3 628844.0 35500.0 0.18 0.3381 0.9669 1974597 ChemDiv1_009511 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3ccc(F)cc3)c4ccccc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A08 compound treatment 628643.0 32800.0 0.15 633972.0 40700.0 0.2 0.2462 0.988 1864072 ChemDiv1_009512 [O-][N+](=O)c1ccc(cc1)c2nc(N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A09 compound treatment 609089.0 13300.0 0.06 649555.0 56200.0 0.28 0.2389 0.8389 1974598 ChemDiv1_009513 CC1CN(CC(C)O1)C2=NC(=O)/C(=C\3/C(=O)N(CC=C)c4ccc(Br)cc34)/S2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A10 compound treatment 636956.0 41100.0 0.18 663574.0 70300.0 0.35 0.3762 0.9557 1504779 ChemDiv1_009514 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A11 compound treatment 735549.0 140000.0 0.63 728951.0 136000.0 0.67 0.9173 0.9994 1974599 ChemDiv1_009515 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4cc(Br)ccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A12 compound treatment 644255.0 48400.0 0.22 639668.0 46300.0 0.23 0.3156 0.9996 1974600 ChemDiv1_009516 CCOc1cc(/C=C\2/NC(=O)NC2=O)cc(Br)c1OCC#C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A13 compound treatment 683876.0 88000.0 0.39 676348.0 83000.0 0.41 0.5695 0.9998 1142666 ChemDiv1_009517 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(OC)c3)c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A14 compound treatment 658682.0 62800.0 0.28 653081.0 59800.0 0.3 0.4083 0.9997 1644663 ChemDiv1_009518 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCCc5cc4c3N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A15 compound treatment 682183.0 86300.0 0.39 672215.0 78900.0 0.39 0.5497 1.0 1394660 ChemDiv1_009519 COc1ccc(cc1Br)c2cn3cccc(C)c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A16 compound treatment 705457.0 110000.0 0.49 715894.0 123000.0 0.61 0.7763 0.9944 1974601 ChemDiv1_009520 OC(=O)c1ccc(cc1Cl)c2ccc(/C=C/3\NC(=O)N(Cc4ccc(Cl)cc4)C3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A17 compound treatment 787343.0 192000.0 0.86 730166.0 137000.0 0.68 1.0855 0.9932 1627312 ChemDiv1_009521 O=C(Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A18 compound treatment 663096.0 67300.0 0.3 652194.0 58900.0 0.29 0.4191 0.9999 1246856 ChemDiv1_009522 C1CCN(CC1)c2nc(nc(n2)N3CCNCC3)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A19 compound treatment 663005.0 67200.0 0.3 647649.0 54300.0 0.27 0.4029 0.9985 1524561 ChemDiv1_009523 CCOC(=O)c1c(C)oc2ccc(OCc3c(OC)ccc4cc(Br)ccc34)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A20 compound treatment 644156.0 48300.0 0.22 647028.0 53700.0 0.27 0.3411 0.9947 1307670 ChemDiv1_009524 COCc1cc(C)nc2sc(C(=O)Nc3ccc(Br)c(Cl)c3)c(N)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A21 compound treatment 633111.0 37300.0 0.17 644336.0 51000.0 0.25 0.2967 0.9797 1974602 ChemDiv1_009525 COCCN(CCOC)c1nc(nc2ccccc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A22 compound treatment 627005.0 31200.0 0.14 613892.0 20600.0 0.1 0.1707 0.9881 1358341 ChemDiv1_009526 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A23 mock treatment 616575.0 20700.0 0.09 611626.0 18300.0 0.09 0.1298 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 A24 mock treatment 511320.0 -84500.0 -0.38 610856.0 17500.0 0.09 -0.2061 -0.5309 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B01 compound treatment 585777.0 -10100.0 -0.05 578815.0 -14500.0 -0.07 -0.0826 -0.9747 1577370 ChemDiv1_009527 Nc1nc(CSc2nc3ccccc3s2)nc(n1)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B02 compound treatment 638127.0 42300.0 0.19 619497.0 26200.0 0.13 0.2256 0.983 1852878 ChemDiv1_009528 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B03 compound treatment 675803.0 80000.0 0.36 668679.0 75400.0 0.37 0.5171 0.9998 1974603 ChemDiv1_009529 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B04 compound treatment 678245.0 82400.0 0.37 667975.0 74700.0 0.37 0.5224 1.0 1852886 ChemDiv1_009530 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B05 compound treatment 712231.0 116000.0 0.52 688422.0 95100.0 0.47 0.7016 0.9987 1545122 ChemDiv1_009531 CC1CCc2c(C1)sc3[nH]c(=S)[nH]c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B06 compound treatment 695018.0 99200.0 0.44 672820.0 79500.0 0.39 0.5924 0.9982 1852890 ChemDiv1_009532 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B07 compound treatment 735245.0 139000.0 0.62 703189.0 110000.0 0.54 0.8261 0.9977 1219251 ChemDiv1_009533 CCOc1ccc(cc1Br)C(=O)Nc2cccc(c2)c3nc4cc(C)cc(C)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B08 compound treatment 721035.0 125000.0 0.56 706986.0 114000.0 0.56 0.7944 1.0 1853085 ChemDiv1_009534 COc1cc(cc(OC)c1OC)C2C(=C(N)N(N(C)C)C3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B09 compound treatment 751029.0 155000.0 0.69 755583.0 162000.0 0.8 1.0596 0.9974 1663826 ChemDiv1_009535 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B10 compound treatment 729039.0 133000.0 0.6 723512.0 130000.0 0.64 0.8777 0.9992 1974604 ChemDiv1_009536 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3C)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B11 compound treatment 744739.0 149000.0 0.67 750931.0 158000.0 0.78 1.0234 0.9969 1461697 ChemDiv1_009537 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B12 compound treatment 685663.0 89800.0 0.4 698636.0 105000.0 0.52 0.6532 0.9917 1241988 ChemDiv1_009538 Clc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B13 compound treatment 762057.0 166000.0 0.74 761444.0 168000.0 0.83 1.1151 0.9984 1631740 ChemDiv1_009539 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B14 compound treatment 691036.0 95200.0 0.43 689588.0 96300.0 0.48 0.6385 0.9984 1628280 ChemDiv1_009540 Clc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B15 compound treatment 751673.0 156000.0 0.7 761594.0 168000.0 0.83 1.0827 0.9961 1852843 ChemDiv1_009541 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B16 compound treatment 699036.0 103000.0 0.46 705343.0 112000.0 0.55 0.7191 0.9958 1275882 ChemDiv1_009542 COc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B17 compound treatment 756304.0 160000.0 0.72 758522.0 165000.0 0.82 1.0866 0.9979 1852850 ChemDiv1_009543 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3C)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B18 compound treatment 709784.0 114000.0 0.51 707484.0 114000.0 0.57 0.7606 0.9987 1974605 ChemDiv1_009544 Cc1sc2ncnc(SCC(=O)Nc3ccc(Br)cc3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B19 compound treatment 728005.0 132000.0 0.59 721752.0 128000.0 0.64 0.8682 0.9993 1852857 ChemDiv1_009545 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B20 compound treatment 697258.0 101000.0 0.45 694688.0 101000.0 0.5 0.6761 0.9987 1136198 ChemDiv1_009546 Cc1ccc(OCCn2c(S)nc3c(N)ncnc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B21 compound treatment 703199.0 107000.0 0.48 712826.0 120000.0 0.59 0.7584 0.9946 1460446 ChemDiv1_009547 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B22 compound treatment 656021.0 60200.0 0.27 677578.0 84300.0 0.42 0.4856 0.9776 1974606 ChemDiv1_009548 CCOc1ccc2[nH]c3nc4ccccc4nc3c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B23 mock treatment 650001.0 54200.0 0.24 668447.0 75100.0 0.37 0.4346 0.9785 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 B24 mock treatment 501082.0 -94800.0 -0.42 515431.0 -77900.0 -0.39 -0.5728 -0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C01 compound treatment 622081.0 26200.0 0.12 591516.0 -1800.0 -0.01 0.0768 0.6514 1338440 ChemDiv1_009549 CN(C)S(=O)(=O)c1ccc(cc1)c2cn3cccc(C)c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C02 compound treatment 657568.0 61700.0 0.28 617396.0 24100.0 0.12 0.2797 0.9294 1864034 ChemDiv1_009550 COc1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C03 compound treatment 698678.0 103000.0 0.46 674353.0 81000.0 0.4 0.6094 0.9977 1974607 ChemDiv1_009551 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(Cl)c3)c4ccccc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C04 compound treatment 708221.0 112000.0 0.5 675845.0 82500.0 0.41 0.6448 0.9947 1864048 ChemDiv1_009552 CC(Nc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C05 compound treatment 760795.0 165000.0 0.74 710741.0 117000.0 0.58 0.9335 0.993 1974608 ChemDiv1_009553 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C06 compound treatment 732026.0 136000.0 0.61 678617.0 85300.0 0.42 0.7299 0.984 1864059 ChemDiv1_009554 CCCCN(C)c1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C07 compound treatment 760922.0 165000.0 0.74 736749.0 143000.0 0.71 1.025 0.9998 1974609 ChemDiv1_009555 Clc1ccc(cc1)c2c(OC(=O)CCN3C(=O)/C(=C\c4ccccc4)/SC3=S)ccc5oc(=O)sc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C08 compound treatment 736047.0 140000.0 0.63 715379.0 122000.0 0.6 0.8714 0.9998 1864073 ChemDiv1_009556 CC1CN(CC(C)O1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C09 compound treatment 1039408.0 444000.0 1.99 1043490.0 450000.0 2.23 2.9809 0.9983 1974610 ChemDiv1_009557 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(Cc3ccccc3)c4ccc(Br)cc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C10 compound treatment 760735.0 165000.0 0.74 712494.0 119000.0 0.59 0.9394 0.9939 1974611 ChemDiv1_009558 CS(=O)(=O)c1cc([N+](=O)[O-])c(Sc2nc3ccccc3s2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C11 compound treatment 796278.0 200000.0 0.9 780704.0 187000.0 0.93 1.2908 0.9999 1974612 ChemDiv1_009559 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5cc(Br)ccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C12 compound treatment 775353.0 180000.0 0.8 699853.0 107000.0 0.53 0.9414 0.9792 1488977 ChemDiv1_009560 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3nnc(s3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C13 compound treatment 771397.0 176000.0 0.79 778361.0 185000.0 0.92 1.2039 0.9971 1464415 ChemDiv1_009561 Cc1c(oc2ccccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4nc(C)cc(C)n4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C14 compound treatment 794135.0 198000.0 0.89 737071.0 144000.0 0.71 1.1312 0.994 1420115 ChemDiv1_009562 CCc1nnc(NC(=O)c2sc3nc4CCCCCc4cc3c2N)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C15 compound treatment 790051.0 194000.0 0.87 784208.0 191000.0 0.95 1.2834 0.9991 1518928 ChemDiv1_009563 COc1ccc(cc1Br)c2cn3ccc(C)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C16 compound treatment 774630.0 179000.0 0.8 754211.0 161000.0 0.8 1.1295 1.0 1974613 ChemDiv1_009564 COC(=O)Cn1cc(/C=C/2\NC(=O)N(Cc3ccc(Cl)cc3)C2=O)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C17 compound treatment 816549.0 221000.0 0.99 768412.0 175000.0 0.87 1.3119 0.9979 1925232 ChemDiv1_009565 [O-][N+](=O)c1ccc(COc2ccc3c(=O)c(coc3c2)c4nc5ccccc5s4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C18 compound treatment 894286.0 298000.0 1.34 843418.0 250000.0 1.24 1.8207 0.9993 1160847 ChemDiv1_009566 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3OC)c(=O)n2C1c4ccc(cc4)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C19 compound treatment 762612.0 167000.0 0.75 732554.0 139000.0 0.69 1.0156 0.9992 1974614 ChemDiv1_009567 CCOC(=O)c1c(oc2ccc(OC(=O)COc3c(F)c(F)c(F)c(F)c3F)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C20 compound treatment 725792.0 130000.0 0.58 703173.0 110000.0 0.54 0.7961 0.9994 1974615 ChemDiv1_009568 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)C)ccc1OCC(=O)Nc4ccc(Br)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C21 compound treatment 751837.0 156000.0 0.7 748960.0 156000.0 0.77 1.039 0.9988 1974616 ChemDiv1_009569 Cc1ccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C22 compound treatment 701645.0 106000.0 0.47 660729.0 67400.0 0.33 0.571 0.9854 1974617 ChemDiv1_009570 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C23 mock treatment 705260.0 109000.0 0.49 681031.0 87700.0 0.43 0.6536 0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 C24 mock treatment 503280.0 -92600.0 -0.41 625420.0 32100.0 0.16 -0.1805 -0.4068 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D01 compound treatment 594725.0 -1110.0 0.0 577945.0 -15400.0 -0.08 -0.0574 -0.7517 1974618 ChemDiv1_009571 CCCCCCN(Cc1ccco1)c2nc(nc(n2)N3CCOCC3)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D02 compound treatment 644849.0 49000.0 0.22 628418.0 35100.0 0.17 0.2781 0.9934 1852879 ChemDiv1_009572 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D03 compound treatment 701303.0 105000.0 0.47 670650.0 77300.0 0.38 0.6047 0.9946 1396898 ChemDiv1_009573 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D04 compound treatment 702426.0 107000.0 0.48 679180.0 85900.0 0.43 0.6381 0.9984 1852887 ChemDiv1_009574 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D05 compound treatment 884976.0 289000.0 1.29 845775.0 252000.0 1.25 1.7995 0.9999 1974619 ChemDiv1_009575 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)[N+](=O)[O-])c(=O)n2C1c4ccccc4OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D06 compound treatment 868369.0 273000.0 1.22 863542.0 270000.0 1.34 1.8092 0.9989 1452712 ChemDiv1_009576 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D07 compound treatment 734299.0 138000.0 0.62 709179.0 116000.0 0.57 0.8441 0.9993 1140770 ChemDiv1_009577 COc1ccc(Br)cc1C(=O)Nc2cc(ccc2C)c3nc4cc(C)cc(C)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D08 compound treatment 733980.0 138000.0 0.62 722336.0 129000.0 0.64 0.8892 0.9999 1683511 ChemDiv1_009578 COc1ccc(cc1OC)C2C(=C(N)N(N(C)C)C3=C2C(=O)CC(C3)c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D09 compound treatment 762304.0 166000.0 0.75 762527.0 169000.0 0.84 1.1196 0.9983 1852820 ChemDiv1_009579 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D10 compound treatment 741387.0 146000.0 0.65 730424.0 137000.0 0.68 0.941 0.9998 1974620 ChemDiv1_009580 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3cccc(C)c3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D11 compound treatment 768032.0 172000.0 0.77 775639.0 182000.0 0.9 1.1837 0.9969 1852826 ChemDiv1_009581 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D12 compound treatment 690442.0 94600.0 0.42 710077.0 117000.0 0.58 0.7084 0.9883 1609272 ChemDiv1_009582 COc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D13 compound treatment 729336.0 134000.0 0.6 741751.0 148000.0 0.74 0.9425 0.9947 1852837 ChemDiv1_009583 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D14 compound treatment 716718.0 121000.0 0.54 717054.0 124000.0 0.61 0.816 0.9981 1623340 ChemDiv1_009584 Brc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D15 compound treatment 789508.0 194000.0 0.87 758165.0 165000.0 0.82 1.1905 0.9996 1852844 ChemDiv1_009585 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D16 compound treatment 710312.0 114000.0 0.51 721305.0 128000.0 0.63 0.8107 0.9944 1387715 ChemDiv1_009586 C(Nc1nc(nc2ccccc12)N3CCN(Cc4ccccc4)CC3)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D17 compound treatment 762430.0 167000.0 0.75 752171.0 159000.0 0.79 1.0838 0.9996 1852852 ChemDiv1_009587 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D18 compound treatment 752793.0 157000.0 0.7 716713.0 123000.0 0.61 0.929 0.9976 1293891 ChemDiv1_009588 CCOc1ccc(Cc2nnc(S)o2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D19 compound treatment 758803.0 163000.0 0.73 748687.0 155000.0 0.77 1.0601 0.9996 1852858 ChemDiv1_009589 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D20 compound treatment 746104.0 150000.0 0.67 704617.0 111000.0 0.55 0.8655 0.9951 1713647 ChemDiv1_009590 COc1ccc(Br)cc1C(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D21 compound treatment 758928.0 163000.0 0.73 735974.0 143000.0 0.71 1.0159 0.9999 1647959 ChemDiv1_009591 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D22 compound treatment 702595.0 107000.0 0.48 704364.0 111000.0 0.55 0.7269 0.9975 1974621 ChemDiv1_009592 C(Sc1nnc(o1)c2ccco2)c3nc4ccccc4[nH]3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D23 mock treatment 676409.0 80600.0 0.36 664419.0 71100.0 0.35 0.5041 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 D24 mock treatment 504892.0 -90900.0 -0.41 528489.0 -64800.0 -0.32 -0.515 -0.9931 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E01 compound treatment 618044.0 22200.0 0.1 592708.0 -612.0 0.0 0.0682 0.6852 1437406 ChemDiv1_009593 CN(C)S(=O)(=O)c1ccc(cc1)c2cn3cc(Cl)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E02 compound treatment 632575.0 36700.0 0.16 631689.0 38400.0 0.19 0.2507 0.9974 1864039 ChemDiv1_009594 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E03 compound treatment 731432.0 136000.0 0.61 694643.0 101000.0 0.5 0.7841 0.9955 1974622 ChemDiv1_009595 Brc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E04 compound treatment 721996.0 126000.0 0.56 687167.0 93800.0 0.46 0.7281 0.9953 1864049 ChemDiv1_009596 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E05 compound treatment 767703.0 172000.0 0.77 725531.0 132000.0 0.65 1.0071 0.9968 1974623 ChemDiv1_009597 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCC(=O)O)C3=O)/c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E06 compound treatment 719154.0 123000.0 0.55 702630.0 109000.0 0.54 0.7732 1.0 1864062 ChemDiv1_009598 [O-][N+](=O)c1ccc(cc1)c2nc(N(CC=C)CC=C)c3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E07 compound treatment 768736.0 173000.0 0.77 728940.0 136000.0 0.67 1.0223 0.9975 1974624 ChemDiv1_009599 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E08 compound treatment 764612.0 169000.0 0.76 738209.0 145000.0 0.72 1.0418 0.9997 1864074 ChemDiv1_009600 CN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E09 compound treatment 800234.0 204000.0 0.91 785829.0 193000.0 0.95 1.3213 0.9998 1974625 ChemDiv1_009601 OC(=O)CN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E10 compound treatment 730917.0 135000.0 0.6 751627.0 158000.0 0.78 0.9821 0.9917 1556877 ChemDiv1_009602 CCc1ccc(NC(=O)Cn2cnc(SCc3ccccc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E11 compound treatment 789030.0 193000.0 0.86 782535.0 189000.0 0.94 1.2743 0.9992 1218295 ChemDiv1_009603 Cc1cc(C)c(OCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E12 compound treatment 975827.0 380000.0 1.7 972679.0 379000.0 1.88 2.5316 0.9988 1974626 ChemDiv1_009604 CCc1nnc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4ccccc4)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E13 compound treatment 794424.0 199000.0 0.89 762027.0 169000.0 0.84 1.2195 0.9995 1731593 ChemDiv1_009605 Cc1cccn2cc(nc12)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E14 compound treatment 766050.0 170000.0 0.76 756654.0 163000.0 0.81 1.1109 0.9995 1421323 ChemDiv1_009606 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Br)o3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E15 compound treatment 819191.0 223000.0 1.0 787317.0 194000.0 0.96 1.3865 0.9998 1713093 ChemDiv1_009607 COc1ccc(cc1Br)c2cn3cc(C)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E16 compound treatment 787954.0 192000.0 0.86 775129.0 182000.0 0.9 1.245 0.9997 1974627 ChemDiv1_009608 Cc1cc(/C=C/2\NC(=O)N(Cc3ccc(Cl)cc3)C2=O)c(C)n1c4cc(C)ccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E17 compound treatment 778889.0 183000.0 0.82 754902.0 162000.0 0.8 1.1454 0.9999 1364315 ChemDiv1_009609 CCOC(=O)c1c(oc2ccc(OC(=O)c3cc4ccccc4o3)cc12)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E18 compound treatment 1179056.0 583000.0 2.61 1084263.0 491000.0 2.43 3.5658 0.9994 1469701 ChemDiv1_009610 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(C)n(C)c3C)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E19 compound treatment 788920.0 193000.0 0.86 735043.0 142000.0 0.7 1.1076 0.9947 1439334 ChemDiv1_009611 Clc1cccc(COc2ccc3cc(c4nc5ccccc5s4)c(=O)oc3c2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E20 compound treatment 760052.0 164000.0 0.74 684379.0 91100.0 0.45 0.8388 0.9725 1974628 ChemDiv1_009612 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccccc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E21 compound treatment 785721.0 190000.0 0.85 735727.0 142000.0 0.71 1.0999 0.9957 1974629 ChemDiv1_009613 CCc1ccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E22 compound treatment 746994.0 151000.0 0.68 702155.0 109000.0 0.54 0.8597 0.9937 1974630 ChemDiv1_009614 CCS(=O)(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E23 mock treatment 718329.0 122000.0 0.55 701604.0 108000.0 0.54 0.767 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 E24 mock treatment 541806.0 -54000.0 -0.24 607204.0 13900.0 0.07 -0.1224 -0.4867 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F01 compound treatment 607559.0 11700.0 0.05 580560.0 -12800.0 -0.06 -0.0076 -0.0924 1621170 ChemDiv1_009615 COc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)Nc3ccc(F)c(F)c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F02 compound treatment 652000.0 56200.0 0.25 615513.0 22200.0 0.11 0.2555 0.9312 1852880 ChemDiv1_009616 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F03 compound treatment 708092.0 112000.0 0.5 668132.0 74800.0 0.37 0.6174 0.9888 1239070 ChemDiv1_009617 NC(=O)CSc1nc2sc3CCCc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F04 compound treatment 691942.0 96100.0 0.43 644224.0 50900.0 0.25 0.4825 0.9676 1470920 ChemDiv1_009618 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5ccccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F05 compound treatment 734355.0 139000.0 0.62 708887.0 116000.0 0.57 0.8433 0.9992 1947100 ChemDiv1_009619 OC1=C(C(N(C1=O)c2nc3ccccc3s2)c4cccc(c4)[N+](=O)[O-])C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F06 compound treatment 715565.0 120000.0 0.54 672149.0 78800.0 0.39 0.6551 0.9879 1612061 ChemDiv1_009620 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccsc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F07 compound treatment 715649.0 120000.0 0.54 721235.0 128000.0 0.63 0.8273 0.9966 1437574 ChemDiv1_009621 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)c3nc4cc(Cl)cc(Cl)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F08 compound treatment 727708.0 132000.0 0.59 702017.0 109000.0 0.54 0.7982 0.9989 1974631 ChemDiv1_009622 [O-][N+](=O)c1ccccc1NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2CC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F09 compound treatment 753700.0 158000.0 0.71 718602.0 125000.0 0.62 0.9385 0.9979 1852821 ChemDiv1_009623 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F10 compound treatment 707520.0 112000.0 0.5 697334.0 104000.0 0.52 0.7179 0.9999 1974632 ChemDiv1_009624 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3Cl)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F11 compound treatment 739086.0 143000.0 0.64 728664.0 135000.0 0.67 0.9275 0.9998 1852830 ChemDiv1_009625 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F12 compound treatment 688771.0 92900.0 0.42 705353.0 112000.0 0.55 0.6866 0.9899 1236128 ChemDiv1_009626 CCOc1ccc(Nc2nc(N3CCOCC3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F13 compound treatment 745747.0 150000.0 0.67 744785.0 151000.0 0.75 1.0051 0.9984 1852838 ChemDiv1_009627 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(C)C)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F14 compound treatment 708715.0 113000.0 0.51 684670.0 91400.0 0.45 0.6773 0.9985 1677893 ChemDiv1_009628 Fc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F15 compound treatment 790776.0 195000.0 0.87 770628.0 177000.0 0.88 1.2381 1.0 1441261 ChemDiv1_009629 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F16 compound treatment 741283.0 145000.0 0.65 716143.0 123000.0 0.61 0.8906 0.9994 1382426 ChemDiv1_009630 C(Nc1nc(nc2ccccc12)N3CCN(CC3)c4ccccc4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F17 compound treatment 770160.0 174000.0 0.78 745430.0 152000.0 0.75 1.0846 0.9998 1209943 ChemDiv1_009631 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F18 compound treatment 795701.0 200000.0 0.89 744585.0 151000.0 0.75 1.1625 0.9961 1974633 ChemDiv1_009632 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/NC(=S)NC3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F19 compound treatment 749798.0 154000.0 0.69 704417.0 111000.0 0.55 0.8765 0.9938 1852862 ChemDiv1_009633 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F20 compound treatment 730750.0 135000.0 0.6 696342.0 103000.0 0.51 0.7879 0.9965 1611495 ChemDiv1_009634 CCOc1cc(cc(OCC)c1OCC)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F21 compound treatment 758403.0 163000.0 0.73 717320.0 124000.0 0.61 0.9489 0.9964 1475081 ChemDiv1_009635 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccs3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F22 compound treatment 715867.0 120000.0 0.54 676177.0 82900.0 0.41 0.6702 0.9912 1974634 ChemDiv1_009636 Brc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F23 mock treatment 678035.0 82200.0 0.37 678952.0 85600.0 0.42 0.5601 0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 F24 mock treatment 503144.0 -92700.0 -0.41 512535.0 -80800.0 -0.4 -0.5764 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G01 compound treatment 599183.0 3350.0 0.01 589298.0 -4020.0 -0.02 -0.0035 -0.1401 1610349 ChemDiv1_009637 Cc1cccn2cc(nc12)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G02 compound treatment 626508.0 30700.0 0.14 625205.0 31900.0 0.16 0.2088 0.9976 1874117 ChemDiv1_009638 COC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G03 compound treatment 718105.0 122000.0 0.55 670398.0 77100.0 0.38 0.657 0.9845 1974635 ChemDiv1_009639 Brc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G04 compound treatment 698186.0 102000.0 0.46 676642.0 83300.0 0.41 0.6158 0.9986 1864051 ChemDiv1_009640 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G05 compound treatment 740590.0 145000.0 0.65 715549.0 122000.0 0.61 0.8863 0.9994 1974636 ChemDiv1_009641 FC(F)(F)c1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G06 compound treatment 714753.0 119000.0 0.53 700239.0 107000.0 0.53 0.7509 1.0 1974637 ChemDiv1_009642 COCCN(CCOC)c1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G07 compound treatment 764649.0 169000.0 0.76 741773.0 148000.0 0.74 1.0544 0.9999 1974638 ChemDiv1_009643 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G08 compound treatment 739415.0 144000.0 0.64 711303.0 118000.0 0.58 0.8677 0.9989 1864075 ChemDiv1_009644 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G09 compound treatment 773481.0 178000.0 0.8 748454.0 155000.0 0.77 1.1057 0.9999 1974639 ChemDiv1_009645 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G10 compound treatment 731953.0 136000.0 0.61 733657.0 140000.0 0.7 0.9224 0.9978 1686350 ChemDiv1_009646 COC(=O)c1ccccc1NC(=O)Cn2c(SCc3ccccc3)nc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G11 compound treatment 755411.0 160000.0 0.71 735856.0 143000.0 0.71 1.0044 1.0 1236222 ChemDiv1_009647 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cccc(C)c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G12 compound treatment 1694699.0 1100000.0 4.92 1751746.0 1160000.0 5.74 7.536 0.9971 1974640 ChemDiv1_009648 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc(cc(c4c3N)C(F)(F)F)c5ccccc5)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G13 compound treatment 766805.0 171000.0 0.77 722250.0 129000.0 0.64 0.9928 0.996 1687733 ChemDiv1_009649 COc1ccc(cc1F)c2cn3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G14 compound treatment 755890.0 160000.0 0.72 697661.0 104000.0 0.52 0.8721 0.9872 1974641 ChemDiv1_009650 CCc1ccc(cc1)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G15 compound treatment 774090.0 178000.0 0.8 760825.0 168000.0 0.83 1.151 0.9998 1191057 ChemDiv1_009651 COc1ccc(cc1Br)c2cn3cc(Cl)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G16 compound treatment 838478.0 243000.0 1.09 795182.0 202000.0 1.0 1.4751 0.9991 1974642 ChemDiv1_009652 [O-][N+](=O)c1ccc(c2ccc(/C=C\3/NC(=O)N(Cc4ccc(Cl)cc4)C3=O)o2)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G17 compound treatment 765637.0 170000.0 0.76 770739.0 177000.0 0.88 1.1589 0.9974 1555311 ChemDiv1_009653 CCOC(=O)c1c(oc2ccc(OC(=O)c3ccccc3OC)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G18 compound treatment 2219634.0 1620000.0 7.27 2113954.0 1520000.0 7.53 10.4664 0.9998 1164078 ChemDiv1_009654 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(C)n(C)c3C)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G19 compound treatment 773271.0 177000.0 0.79 748152.0 155000.0 0.77 1.104 0.9998 1974643 ChemDiv1_009655 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3ccc(Br)cc3)C)cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G20 compound treatment 740027.0 144000.0 0.65 701450.0 108000.0 0.54 0.8352 0.9957 1974644 ChemDiv1_009656 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G21 compound treatment 769619.0 174000.0 0.78 744067.0 151000.0 0.75 1.0781 0.9998 1974645 ChemDiv1_009657 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CCCOc3ccc(Cl)cc3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G22 compound treatment 764327.0 168000.0 0.75 713232.0 120000.0 0.59 0.9534 0.993 1974646 ChemDiv1_009658 CS(=O)(=O)c1sc2nc(cc(c3ccccc3)c2c1N)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G23 mock treatment 717544.0 122000.0 0.54 700839.0 108000.0 0.53 0.7619 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 G24 mock treatment 544752.0 -51100.0 -0.23 657577.0 64300.0 0.32 0.0634 0.1617 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H01 compound treatment 587550.0 -8290.0 -0.04 564821.0 -28500.0 -0.14 -0.1261 -0.8636 1685082 ChemDiv1_009659 COc1ccc(C2NC(=O)NC(=C2C(=O)Nc3ccc(F)c(F)c3)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H02 compound treatment 650269.0 54400.0 0.24 606307.0 13000.0 0.06 0.2178 0.8642 1852881 ChemDiv1_009660 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3sccc3C)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H03 compound treatment 702845.0 107000.0 0.48 648106.0 54800.0 0.27 0.5306 0.9638 1974647 ChemDiv1_009661 COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H04 compound treatment 691422.0 95600.0 0.43 648979.0 55700.0 0.28 0.4975 0.9774 1254487 ChemDiv1_009662 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H05 compound treatment 735105.0 139000.0 0.62 685907.0 92600.0 0.46 0.7651 0.9886 1785887 ChemDiv1_009663 OC1=C(C(N(C1=O)c2nc3ccccc3s2)c4ccc5OCOc5c4)C(=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H06 compound treatment 722921.0 127000.0 0.57 666960.0 73600.0 0.36 0.6602 0.9769 1852906 ChemDiv1_009664 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(C)sc3C)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H07 compound treatment 721574.0 126000.0 0.56 686150.0 92800.0 0.46 0.7232 0.995 1572697 ChemDiv1_009665 CCOc1ccc(cc1Cl)C(=O)Nc2ccc(cc2)c3nc4cc(C)cc(C)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H08 compound treatment 748926.0 153000.0 0.69 695459.0 102000.0 0.51 0.8424 0.9889 1974648 ChemDiv1_009666 CCc1cc2c(=O)n(CC=C)c(SCC(=O)c3ccc(OC)cc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H09 compound treatment 757516.0 162000.0 0.72 705265.0 112000.0 0.55 0.9039 0.9914 1852822 ChemDiv1_009667 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)c(OC)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H10 compound treatment 730767.0 135000.0 0.6 711638.0 118000.0 0.59 0.8415 0.9999 1974649 ChemDiv1_009668 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3cccc(Cl)c3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H11 compound treatment 739273.0 143000.0 0.64 730457.0 137000.0 0.68 0.9344 0.9996 1678038 ChemDiv1_009669 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H12 compound treatment 741352.0 146000.0 0.65 655700.0 62400.0 0.31 0.6791 0.9419 1573809 ChemDiv1_009670 CCOc1ccc(cc1)n2c(SCC(=O)N)nc3sc4CCCCc4c3c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H13 compound treatment 758141.0 162000.0 0.73 719755.0 126000.0 0.63 0.9566 0.9973 1852839 ChemDiv1_009671 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H14 compound treatment 714997.0 119000.0 0.53 639223.0 45900.0 0.23 0.538 0.9278 1606595 ChemDiv1_009672 Cc1ccc(C)c(Nc2nc(NCc3ccco3)c4ccccc4n2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H15 compound treatment 782928.0 187000.0 0.84 713116.0 120000.0 0.59 1.0118 0.9858 1852845 ChemDiv1_009673 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H16 compound treatment 728521.0 133000.0 0.59 714261.0 121000.0 0.6 0.8436 1.0 1556983 ChemDiv1_009674 OCCN1CCN(CC1)c2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H17 compound treatment 787806.0 192000.0 0.86 717033.0 124000.0 0.61 1.041 0.9863 1196159 ChemDiv1_009675 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(OC)c3OC)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H18 compound treatment 741051.0 145000.0 0.65 692419.0 99100.0 0.49 0.8068 0.9904 1974650 ChemDiv1_009676 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5cc(Cl)cc(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H19 compound treatment 766203.0 170000.0 0.76 669041.0 75700.0 0.38 0.8045 0.9466 1852863 ChemDiv1_009677 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H20 compound treatment 723924.0 128000.0 0.57 657931.0 64600.0 0.32 0.6318 0.9621 1272595 ChemDiv1_009678 COc1ccc(cc1Br)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H21 compound treatment 744263.0 148000.0 0.66 691300.0 98000.0 0.49 0.813 0.9881 1852874 ChemDiv1_009679 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H22 compound treatment 721974.0 126000.0 0.56 668248.0 74900.0 0.37 0.6617 0.9793 1974651 ChemDiv1_009680 Brc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2Cc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H23 mock treatment 691834.0 96000.0 0.43 665933.0 72600.0 0.36 0.5582 0.9961 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 H24 mock treatment 526373.0 -69500.0 -0.31 502474.0 -90800.0 -0.45 -0.5381 -0.9837 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I01 compound treatment 604347.0 8510.0 0.04 576967.0 -16400.0 -0.08 -0.0303 -0.3389 1197614 ChemDiv1_009681 Cc1ccn2cc(nc2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I02 compound treatment 667901.0 72100.0 0.32 610253.0 16900.0 0.08 0.2874 0.8623 1864040 ChemDiv1_009682 [O-][N+](=O)c1ccc(cc1)c2nc(Nc3cccc(c3)[N+](=O)[O-])c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I03 compound treatment 714039.0 118000.0 0.53 651939.0 58600.0 0.29 0.5795 0.9601 1974652 ChemDiv1_009683 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(Br)c3)c4ccccc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I04 compound treatment 695520.0 99700.0 0.45 646223.0 52900.0 0.26 0.5008 0.9678 1864052 ChemDiv1_009684 [O-][N+](=O)c1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I05 compound treatment 708221.0 112000.0 0.5 661490.0 68200.0 0.34 0.5945 0.9812 1974653 ChemDiv1_009685 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I06 compound treatment 710480.0 115000.0 0.51 663036.0 69700.0 0.35 0.6071 0.9814 1864067 ChemDiv1_009686 [O-][N+](=O)c1ccc(cc1)c2nc(N3CCCCCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I07 compound treatment 757778.0 162000.0 0.72 734741.0 141000.0 0.7 1.008 0.9999 1974654 ChemDiv1_009687 COc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(CCC(=O)O)C3=O)/c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I08 compound treatment 762063.0 166000.0 0.74 696850.0 104000.0 0.51 0.8888 0.9835 1864076 ChemDiv1_009688 CN(C1CCN(C)CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I09 compound treatment 762250.0 166000.0 0.74 726021.0 133000.0 0.66 0.9916 0.9981 1974655 ChemDiv1_009689 OC(=O)CCCN1C(=O)/C(=C\2/C(=O)N(CC(=O)O)c3ccc(Br)cc23)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I10 compound treatment 733818.0 138000.0 0.62 721111.0 128000.0 0.63 0.8844 0.9999 1395277 ChemDiv1_009690 Cc1ccc(cc1)S(=O)(=O)n2c(SCc3ccccc3)nc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I11 compound treatment 772194.0 176000.0 0.79 711156.0 118000.0 0.58 0.971 0.989 1225162 ChemDiv1_009691 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3ccc(C)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I12 compound treatment 1550492.0 955000.0 4.27 1568107.0 975000.0 4.83 6.4363 0.9981 1974656 ChemDiv1_009692 CCc1nnc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I13 compound treatment 752126.0 156000.0 0.7 691273.0 98000.0 0.49 0.8378 0.984 1540085 ChemDiv1_009693 COc1ccc(cc1F)c2cn3cccc(C)c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I14 compound treatment 775677.0 180000.0 0.81 728796.0 135000.0 0.67 1.0438 0.9959 1974657 ChemDiv1_009694 CCc1ccc(cc1)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCC(=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I15 compound treatment 787536.0 192000.0 0.86 747578.0 154000.0 0.76 1.1471 0.9983 1742353 ChemDiv1_009695 COC(=O)C1=C(C)NC(=C(C1c2ccc(OC(=O)c3oc4ccccc4c3C)c(OC)c2)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I16 compound treatment 787510.0 192000.0 0.86 711455.0 118000.0 0.59 1.0205 0.9826 1974658 ChemDiv1_009696 OCC1(OC2C=C1)C3C2C(=O)N(C3=O)c4ccc(Cl)c(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I17 compound treatment 785779.0 190000.0 0.85 727110.0 134000.0 0.66 1.0699 0.9924 1924936 ChemDiv1_009697 COCCOC(=O)c1c(C)oc2ccc(OC(=O)c3ccc(OC)c(OC)c3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I18 compound treatment 1114305.0 518000.0 2.32 1111238.0 518000.0 2.57 3.4553 0.9987 1605991 ChemDiv1_009698 CCOC(=O)C1=C(C)N=c2sc(=Cc3c(OC)cc(OC)cc3OC)c(=O)n2C1c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I19 compound treatment 746179.0 150000.0 0.67 711371.0 118000.0 0.58 0.8894 0.9976 1974659 ChemDiv1_009699 CCOC(=O)c1ccc(cc1)N2N=C(C)/C(=C\c3ccc(OCc4ccccc4)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I20 compound treatment 722921.0 127000.0 0.57 661105.0 67800.0 0.34 0.6397 0.9684 1974660 ChemDiv1_009700 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)c2nc3ccccc3s2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I21 compound treatment 723495.0 128000.0 0.57 724931.0 132000.0 0.65 0.8651 0.9978 1974661 ChemDiv1_009701 Cc1cccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I22 compound treatment 654681.0 58800.0 0.26 673798.0 80500.0 0.4 0.4682 0.9798 1974662 ChemDiv1_009702 Cc1cc(C)c(C#N)c(SCC(O)CS(=O)(=O)Cc2ccc(Cl)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I23 mock treatment 710935.0 115000.0 0.52 655361.0 62000.0 0.31 0.5816 0.9695 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 I24 mock treatment 569512.0 -26300.0 -0.12 611851.0 18500.0 0.09 -0.0184 -0.1232 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J01 compound treatment 605607.0 9770.0 0.04 564659.0 -28700.0 -0.14 -0.0695 -0.4676 1974663 ChemDiv1_009703 CC1=C(C(NC(=O)N1)c2ccccc2Br)C(=O)Nc3ccc(C)cc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J02 compound treatment 645379.0 49500.0 0.22 591625.0 -1690.0 -0.01 0.1509 0.6799 1852882 ChemDiv1_009704 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J03 compound treatment 670640.0 74800.0 0.33 634681.0 41400.0 0.2 0.3817 0.9722 1974664 ChemDiv1_009705 CN(C)c1nc(OCCOC(=O)COc2ccc(Cl)cc2Cl)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J04 compound treatment 687054.0 91200.0 0.41 633260.0 39900.0 0.2 0.4286 0.9447 1427700 ChemDiv1_009706 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc4OCOc4c3)C1=O)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J05 compound treatment 703902.0 108000.0 0.48 674137.0 80800.0 0.4 0.6252 0.9956 1374090 ChemDiv1_009707 COc1ccc(OC)c(c1)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J06 compound treatment 717272.0 121000.0 0.54 657725.0 64400.0 0.32 0.61 0.9678 1852907 ChemDiv1_009708 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(C)sc3C)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J07 compound treatment 729601.0 134000.0 0.6 647576.0 54300.0 0.27 0.6135 0.9347 1974665 ChemDiv1_009709 CCOc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccc(cc2)c3nc4cc(C)cc(C)c4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J08 compound treatment 734131.0 138000.0 0.62 672337.0 79000.0 0.39 0.7145 0.9756 1974666 ChemDiv1_009710 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccccc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J09 compound treatment 743884.0 148000.0 0.66 697389.0 104000.0 0.52 0.8332 0.9923 1852823 ChemDiv1_009711 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J10 compound treatment 731948.0 136000.0 0.61 652697.0 59400.0 0.29 0.6388 0.9442 1974667 ChemDiv1_009712 CCOc1ccc(NC(=O)CSc2nc3sc(CC)cc3c(=O)n2CC=C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J11 compound treatment 759603.0 164000.0 0.73 697975.0 105000.0 0.52 0.885 0.9856 1213599 ChemDiv1_009713 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3OC)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J12 compound treatment 746371.0 151000.0 0.67 689850.0 96500.0 0.48 0.8146 0.9859 1201460 ChemDiv1_009714 CN1CCN(CC1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J13 compound treatment 758911.0 163000.0 0.73 683449.0 90100.0 0.45 0.8319 0.9722 1513934 ChemDiv1_009715 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J14 compound treatment 738237.0 142000.0 0.64 653245.0 59900.0 0.3 0.6606 0.9395 1143902 ChemDiv1_009716 Clc1cccc(Nc2nc(NCc3ccco3)c4ccccc4n2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J15 compound treatment 780060.0 184000.0 0.82 693424.0 100000.0 0.5 0.9338 0.9704 1852846 ChemDiv1_009717 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J16 compound treatment 750708.0 155000.0 0.69 680397.0 87100.0 0.43 0.7952 0.9739 1616178 ChemDiv1_009718 COc1ccccc1Nc2nc(N3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J17 compound treatment 788167.0 192000.0 0.86 707427.0 114000.0 0.57 1.0085 0.9792 1852853 ChemDiv1_009719 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J18 compound treatment 741575.0 146000.0 0.65 665198.0 71900.0 0.36 0.7131 0.9594 1974668 ChemDiv1_009720 CCOC(=O)c1ccc(cc1)N2N=C(C)/C(=C\c3ccc(o3)c4ccc(Cl)c(c4)C(=O)O)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J19 compound treatment 779292.0 183000.0 0.82 627649.0 34300.0 0.17 0.7009 0.8358 1623863 ChemDiv1_009721 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(F)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J20 compound treatment 723973.0 128000.0 0.57 639620.0 46300.0 0.23 0.5678 0.9191 1273951 ChemDiv1_009722 CCOc1ccc(cc1Br)C(=O)Nc2cc(ccc2Cl)c3nc4cc(C)ccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J21 compound treatment 768356.0 173000.0 0.77 673501.0 80200.0 0.4 0.8269 0.9522 1852875 ChemDiv1_009723 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J22 compound treatment 699934.0 104000.0 0.47 623178.0 29900.0 0.15 0.4341 0.8879 1974669 ChemDiv1_009724 Brc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2Cc4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J23 mock treatment 707168.0 111000.0 0.5 657393.0 64100.0 0.32 0.5768 0.9763 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 J24 mock treatment 511959.0 -83900.0 -0.38 522318.0 -71000.0 -0.35 -0.5142 -0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K01 compound treatment 595136.0 -700.0 0.0 572034.0 -21300.0 -0.11 -0.0768 -0.7278 1272298 ChemDiv1_009725 Cc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K02 compound treatment 652994.0 57200.0 0.26 598246.0 4930.0 0.02 0.1982 0.7711 1864042 ChemDiv1_009726 OC(=O)c1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K03 compound treatment 677349.0 81500.0 0.36 621680.0 28400.0 0.14 0.3574 0.914 1974670 ChemDiv1_009727 Clc1ccccc1c2c(OC(=O)CCN3C(=O)/C(=C/c4cccs4)/SC3=S)ccc5oc(=O)sc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K04 compound treatment 671195.0 75400.0 0.34 624651.0 31300.0 0.16 0.3483 0.9379 1864053 ChemDiv1_009728 [O-][N+](=O)c1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K05 compound treatment 702738.0 107000.0 0.48 663442.0 70100.0 0.35 0.584 0.9876 1974671 ChemDiv1_009729 OC(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC(=O)Nc3cccc(c3)C(F)(F)F)c4ccccc24)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K06 compound treatment 708726.0 113000.0 0.51 648721.0 55400.0 0.27 0.5514 0.9589 1864068 ChemDiv1_009730 CC1CCCCN1c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K07 compound treatment 743386.0 148000.0 0.66 696805.0 103000.0 0.51 0.8295 0.9922 1974672 ChemDiv1_009731 Brc1ccc2N(CC=C)C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K08 compound treatment 706945.0 111000.0 0.5 664685.0 71400.0 0.35 0.6017 0.986 1326814 ChemDiv1_009732 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K09 compound treatment 812389.0 217000.0 0.97 699107.0 106000.0 0.52 1.056 0.9583 1974673 ChemDiv1_009733 OC(=O)CN1C(=O)/C(=C/2\SC(=S)N(CCS(=O)(=O)O)C2=O)/c3cc(Br)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K10 compound treatment 739268.0 143000.0 0.64 671943.0 78600.0 0.39 0.7294 0.9713 1974674 ChemDiv1_009734 Cc1ccsc1/C=C\2/NC(=O)NC2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K11 compound treatment 729932.0 134000.0 0.6 688211.0 94900.0 0.47 0.7568 0.9927 1558761 ChemDiv1_009735 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cc(C)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K12 compound treatment 821612.0 226000.0 1.01 730867.0 138000.0 0.68 1.1965 0.9816 1974675 ChemDiv1_009736 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K13 compound treatment 757783.0 162000.0 0.72 670016.0 76700.0 0.38 0.7813 0.9545 1719671 ChemDiv1_009737 COc1ccc(cc1F)c2cn3ccc(C)cc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K14 compound treatment 755085.0 159000.0 0.71 690403.0 97100.0 0.48 0.8441 0.9816 1974676 ChemDiv1_009738 Cc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K15 compound treatment 779141.0 183000.0 0.82 701288.0 108000.0 0.53 0.9584 0.9785 1418704 ChemDiv1_009739 CCOC(=O)c1c(C)n(c2ccc(cc2)N(CC)CC)c3ccc(OCC#C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K16 compound treatment 762986.0 167000.0 0.75 674711.0 81400.0 0.4 0.8142 0.9579 1974677 ChemDiv1_009740 CCOC(=O)c1cc(ccc1Cl)N2C(=O)C3C4OC(C=C4)(C(OC(=O)C)OC(=O)C)C3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K17 compound treatment 773277.0 177000.0 0.79 697758.0 104000.0 0.52 0.9275 0.9784 1230440 ChemDiv1_009741 CCOC(=O)c1c(oc2ccc(OCC(=O)OCc3ccccc3)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K18 compound treatment 1115800.0 520000.0 2.33 966937.0 374000.0 1.85 2.9546 0.9936 1640900 ChemDiv1_009742 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)cc3OC)c(=O)n2C1c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K19 compound treatment 760573.0 165000.0 0.74 682685.0 89400.0 0.44 0.8345 0.9702 1974678 ChemDiv1_009743 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)C(=O)O)C)cc(Br)c1OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K20 compound treatment 747005.0 151000.0 0.68 674334.0 81000.0 0.4 0.7623 0.9689 1145353 ChemDiv1_009744 O=S(=O)(CCSc1nc2CCCCc2cc1C#N)Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K21 compound treatment 726694.0 131000.0 0.59 654330.0 61000.0 0.3 0.6279 0.9526 1864030 ChemDiv1_009745 Oc1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K22 compound treatment 710496.0 115000.0 0.51 649446.0 56100.0 0.28 0.5595 0.9585 1360308 ChemDiv1_009746 OC(COc1ccc(Cl)cc1)CSc2nc3CCCCc3cc2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K23 mock treatment 721348.0 126000.0 0.56 654668.0 61300.0 0.3 0.6122 0.9584 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 K24 mock treatment 491513.0 -104000.0 -0.47 599116.0 5800.0 0.03 -0.3099 -0.6624 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L01 compound treatment 596136.0 300.0 0.0 550735.0 -42600.0 -0.21 -0.1482 -0.7026 1304147 ChemDiv1_009747 CCOc1cc(ccc1O)C2NC(=O)NC(=C2C(=O)Nc3ccc(C)cc3C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L02 compound treatment 649328.0 53500.0 0.24 579445.0 -13900.0 -0.07 0.1207 0.4846 1852883 ChemDiv1_009748 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L03 compound treatment 662626.0 66800.0 0.3 611611.0 18300.0 0.09 0.2755 0.8818 1400232 ChemDiv1_009749 CCCCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccc(C)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L04 compound treatment 698657.0 103000.0 0.46 601105.0 7790.0 0.04 0.3527 0.7637 1370204 ChemDiv1_009750 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L05 compound treatment 705276.0 109000.0 0.49 643185.0 49900.0 0.25 0.5211 0.9497 1536631 ChemDiv1_009751 COc1ccc(C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L06 compound treatment 705363.0 110000.0 0.49 616267.0 22900.0 0.11 0.4271 0.8485 1852936 ChemDiv1_009752 CN(C)N1C(=C(C#N)C(C2=C1CC(CC2=O)c3ccccc3)c4ccc(Br)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L07 compound treatment 744027.0 148000.0 0.66 641355.0 48000.0 0.24 0.6373 0.9043 1701183 ChemDiv1_009753 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3C)c4nc5ncccc5o4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L08 compound treatment 700117.0 104000.0 0.47 645626.0 52300.0 0.26 0.5133 0.9614 1974679 ChemDiv1_009754 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(F)cc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L09 compound treatment 750008.0 154000.0 0.69 670240.0 76900.0 0.38 0.7574 0.9608 1852824 ChemDiv1_009755 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L10 compound treatment 728225.0 132000.0 0.59 644371.0 51100.0 0.25 0.5979 0.9279 1974680 ChemDiv1_009756 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(OC)cc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L11 compound treatment 751762.0 156000.0 0.7 637184.0 43900.0 0.22 0.6472 0.8853 1852834 ChemDiv1_009757 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L12 compound treatment 737228.0 141000.0 0.63 637263.0 43900.0 0.22 0.6015 0.8986 1591665 ChemDiv1_009758 OCCN1CCN(CC1)c2nc(NCc3ccccc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L13 compound treatment 751070.0 155000.0 0.69 633182.0 39900.0 0.2 0.631 0.8735 1852840 ChemDiv1_009759 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)c(OC)c3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L14 compound treatment 719842.0 124000.0 0.56 636590.0 43300.0 0.21 0.5441 0.9144 1441651 ChemDiv1_009760 Fc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L15 compound treatment 781932.0 186000.0 0.83 700269.0 107000.0 0.53 0.9637 0.9761 1852847 ChemDiv1_009761 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L16 compound treatment 731598.0 136000.0 0.61 663971.0 70700.0 0.35 0.6772 0.9656 1168079 ChemDiv1_009762 C1CN(CCO1)c2nc(nc3ccccc23)N4CCN(CC4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L17 compound treatment 745787.0 150000.0 0.67 668466.0 75100.0 0.37 0.7379 0.9613 1852854 ChemDiv1_009763 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L18 compound treatment 713110.0 117000.0 0.52 623339.0 30000.0 0.15 0.4764 0.8731 1927246 ChemDiv1_009764 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L19 compound treatment 727078.0 131000.0 0.59 645976.0 52700.0 0.26 0.5999 0.9332 1852870 ChemDiv1_009765 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L20 compound treatment 730177.0 134000.0 0.6 613029.0 19700.0 0.1 0.4943 0.8113 1149777 ChemDiv1_009766 Nc1ncnc2n(CCOc3ccccc3)c(S)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L21 compound treatment 775876.0 180000.0 0.81 674843.0 81500.0 0.4 0.8554 0.949 1349783 ChemDiv1_009767 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OCC)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L22 compound treatment 691035.0 95200.0 0.43 632982.0 39700.0 0.2 0.4403 0.9382 1974681 ChemDiv1_009768 Brc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2Cc4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L23 mock treatment 718517.0 123000.0 0.55 635681.0 42400.0 0.21 0.5367 0.9129 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 L24 mock treatment 509949.0 -85900.0 -0.38 287443.0 -306000.0 -1.52 -1.3433 -0.8593 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M01 compound treatment 596331.0 495.0 0.0 563840.0 -29500.0 -0.15 -0.1017 -0.6963 1321163 ChemDiv1_009769 Clc1ccc2nc(cn2c1)c3ccc(cc3)S(=O)(=O)N4CCCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M02 compound treatment 648991.0 53200.0 0.24 576023.0 -17300.0 -0.09 0.1077 0.4257 1864043 ChemDiv1_009770 OC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M03 compound treatment 700244.0 104000.0 0.47 627886.0 34600.0 0.17 0.4516 0.9072 1974682 ChemDiv1_009771 COc1ccc(cc1)c2c(OC(=O)CCN3C(=O)/C(=C/c4cccs4)/SC3=S)ccc5oc(=O)sc25 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M04 compound treatment 686097.0 90300.0 0.4 598217.0 4900.0 0.02 0.3029 0.7482 1864055 ChemDiv1_009772 CN(C)CCNc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M05 compound treatment 729905.0 134000.0 0.6 642333.0 49000.0 0.24 0.5961 0.9207 1974683 ChemDiv1_009773 Fc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M06 compound treatment 661386.0 65600.0 0.29 610702.0 17400.0 0.09 0.2684 0.8776 1864069 ChemDiv1_009774 CC1CCCN(C1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M07 compound treatment 702575.0 107000.0 0.48 660657.0 67300.0 0.33 0.5737 0.9846 1974684 ChemDiv1_009775 Brc1ccc2N(CC=C)C(=O)/C(=C/3\SC(=S)N(Cc4ccco4)C3=O)/c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M08 compound treatment 710219.0 114000.0 0.51 637322.0 44000.0 0.22 0.5162 0.9276 1307732 ChemDiv1_009776 COc1nccnc1NS(=O)(=O)c2ccc(NC(=O)c3cc4c(ccc5ccccc54)oc3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M09 compound treatment 726541.0 131000.0 0.59 647046.0 53700.0 0.27 0.6019 0.9364 1974685 ChemDiv1_009777 OC(=O)CN1C(=O)/C(=C/2\SC(=NC2=O)N3CCOCC3)/c4cc(Br)ccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M10 compound treatment 704539.0 109000.0 0.49 639243.0 45900.0 0.23 0.5049 0.94 1974686 ChemDiv1_009778 Fc1ccc(NC(=O)COc2ccccc2/C=C\3/NC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M11 compound treatment 728461.0 133000.0 0.59 638697.0 45400.0 0.22 0.5787 0.9117 1123814 ChemDiv1_009779 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cn3cc(Cl)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M12 compound treatment 717304.0 121000.0 0.54 638284.0 45000.0 0.22 0.542 0.9224 1151148 ChemDiv1_009780 Nc1c(sc2nc3CCCc3cc12)C(=O)Nc4nccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M13 compound treatment 733222.0 137000.0 0.61 642149.0 48800.0 0.24 0.6059 0.9169 1191953 ChemDiv1_009781 COc1ccc(cc1F)c2cn3cc(C)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M14 compound treatment 739177.0 143000.0 0.64 641091.0 47800.0 0.24 0.6211 0.9081 1974687 ChemDiv1_009782 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M15 compound treatment 751112.0 155000.0 0.7 688025.0 94700.0 0.47 0.8232 0.9817 1974688 ChemDiv1_009783 CC(C)(C)C(=O)Nc1nc(cs1)C2CCCN2S(=O)(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M16 compound treatment 724669.0 129000.0 0.58 651789.0 58500.0 0.29 0.6126 0.9492 1709254 ChemDiv1_009784 Cc1ccc(cc1NC(=O)c2ccc(C#N)cc2F)c3nc4ncccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M17 compound treatment 758737.0 163000.0 0.73 663141.0 69800.0 0.35 0.7602 0.9419 1974689 ChemDiv1_009785 CCOC(=O)c1c(oc2ccc(OCc3c(F)cccc3Cl)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M18 compound treatment 709299.0 113000.0 0.51 650536.0 57200.0 0.28 0.5596 0.962 1974690 ChemDiv1_009786 COCc1cc(C)nc(SCc2ccc(Cl)cc2Cl)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M19 compound treatment 725405.0 130000.0 0.58 668364.0 75000.0 0.37 0.673 0.9769 1974691 ChemDiv1_009787 COc1ccc(cc1)C2C(=C(N)Oc3c2c(C)nn3c4ccc(Br)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M20 compound treatment 688978.0 93100.0 0.42 632538.0 39200.0 0.19 0.4322 0.9396 1572702 ChemDiv1_009788 CCS(=O)CCSc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M21 compound treatment 704118.0 108000.0 0.48 626638.0 33300.0 0.17 0.4595 0.8973 1864031 ChemDiv1_009789 Oc1ccc(Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M22 compound treatment 705451.0 110000.0 0.49 644298.0 51000.0 0.25 0.5255 0.9523 1243790 ChemDiv1_009790 OC(CSc1nc2CCCCc2cc1C#N)CS(=O)(=O)Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M23 mock treatment 690457.0 94600.0 0.42 627731.0 34400.0 0.17 0.42 0.92 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 M24 mock treatment 572706.0 -23100.0 -0.1 437630.0 -156000.0 -0.77 -0.6186 -0.7949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N01 compound treatment 604290.0 8450.0 0.04 550769.0 -42600.0 -0.21 -0.1223 -0.571 1701246 ChemDiv1_009791 COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)c(OC)c3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N02 compound treatment 646157.0 50300.0 0.23 558271.0 -35000.0 -0.17 0.0365 0.1284 1852884 ChemDiv1_009792 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(c3)[N+](=O)[O-])C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N03 compound treatment 684797.0 89000.0 0.4 589481.0 -3840.0 -0.02 0.2681 0.6726 1680628 ChemDiv1_009793 COc1cc(C)nc(NC(=O)Nc2sc(NS(=O)(=O)c3ccc(C)cc3)nc2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N04 compound treatment 684889.0 89100.0 0.4 589164.0 -4160.0 -0.02 0.2673 0.6697 1852888 ChemDiv1_009794 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N05 compound treatment 711638.0 116000.0 0.52 613306.0 20000.0 0.1 0.4366 0.8272 1522078 ChemDiv1_009795 COc1ccc(cc1OC)C2N(C(=O)C(=C2C(=O)c3ccccc3)O)c4nc5ccccc5s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N06 compound treatment 701502.0 106000.0 0.47 587607.0 -5710.0 -0.03 0.3145 0.6636 1974692 ChemDiv1_009796 CN(C)N1C(=C(C#N)C(C2=C1CC(CC2=O)c3ccccc3)c4ccccc4C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N07 compound treatment 705621.0 110000.0 0.49 616713.0 23400.0 0.12 0.4294 0.8505 1852819 ChemDiv1_009797 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N08 compound treatment 712868.0 117000.0 0.52 613938.0 20600.0 0.1 0.4427 0.8294 1974693 ChemDiv1_009798 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(Cl)cc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N09 compound treatment 732531.0 137000.0 0.61 626191.0 32900.0 0.16 0.5478 0.8652 1296304 ChemDiv1_009799 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3Cl)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N10 compound treatment 699401.0 104000.0 0.46 599518.0 6200.0 0.03 0.3495 0.7523 1307201 ChemDiv1_009800 CCc1cc2c(=O)n(CC=C)c(SCc3nc4ccccc4[nH]3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N11 compound treatment 735822.0 140000.0 0.63 627078.0 33800.0 0.17 0.5613 0.8655 1852835 ChemDiv1_009801 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N12 compound treatment 687143.0 91300.0 0.41 583280.0 -10000.0 -0.05 0.2538 0.6165 1701346 ChemDiv1_009802 Cc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N13 compound treatment 713828.0 118000.0 0.53 622478.0 29200.0 0.14 0.4756 0.8686 1852841 ChemDiv1_009803 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N14 compound treatment 687740.0 91900.0 0.41 561831.0 -31500.0 -0.16 0.1806 0.4105 1143772 ChemDiv1_009804 COc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N15 compound treatment 756886.0 161000.0 0.72 642842.0 49500.0 0.25 0.6832 0.8972 1852848 ChemDiv1_009805 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(C)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N16 compound treatment 730701.0 135000.0 0.6 602272.0 8950.0 0.04 0.4582 0.757 1974694 ChemDiv1_009806 CCc1cc2c(SCC(=O)Nc3ccc(Br)cc3)ncnc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N17 compound treatment 708951.0 113000.0 0.51 640708.0 47400.0 0.23 0.524 0.9389 1852855 ChemDiv1_009807 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)[N+](=O)[O-])C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N18 compound treatment 713643.0 118000.0 0.53 613614.0 20300.0 0.1 0.444 0.827 1974695 ChemDiv1_009808 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccc4COC(=O)c4c3)c5ccc(cc5)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N19 compound treatment 745303.0 149000.0 0.67 641692.0 48400.0 0.24 0.6425 0.9041 1157815 ChemDiv1_009809 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N20 compound treatment 729430.0 134000.0 0.6 618655.0 25300.0 0.13 0.5116 0.8373 1615295 ChemDiv1_009810 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)Cn3cnc4ccccc4c3=O)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N21 compound treatment 733791.0 138000.0 0.62 606154.0 12800.0 0.06 0.4816 0.7758 1852876 ChemDiv1_009811 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N22 compound treatment 705559.0 110000.0 0.49 603085.0 9770.0 0.05 0.3815 0.773 1974696 ChemDiv1_009812 COc1cc(cc(Br)c1OCc2ccccc2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N23 mock treatment 706019.0 110000.0 0.49 608065.0 14700.0 0.07 0.4004 0.8031 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 N24 mock treatment 448381.0 -147000.0 -0.66 428836.0 -164000.0 -0.81 -1.0429 -0.9945 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O01 compound treatment 599149.0 3310.0 0.01 556080.0 -37200.0 -0.18 -0.12 -0.6482 1974697 ChemDiv1_009813 Clc1cccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O02 compound treatment 618274.0 22400.0 0.1 542193.0 -51100.0 -0.25 -0.1081 -0.3966 1974698 ChemDiv1_009814 COCCCNc1nc(nc2ccccc12)c3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O03 compound treatment 651951.0 56100.0 0.25 561887.0 -31400.0 -0.16 0.0675 0.2284 1974699 ChemDiv1_009815 CCOc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=NC3=O)N4CCOCC4)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O04 compound treatment 654367.0 58500.0 0.26 567665.0 -25700.0 -0.13 0.0954 0.3276 1864056 ChemDiv1_009816 [O-][N+](=O)c1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O05 compound treatment 684020.0 88200.0 0.39 596763.0 3440.0 0.02 0.2912 0.737 1974700 ChemDiv1_009817 Fc1ccc(NC(=O)CN2C(=O)/C(=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O)/c5ccccc25)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O06 compound treatment 664291.0 68500.0 0.31 571678.0 -21600.0 -0.11 0.1409 0.4339 1864070 ChemDiv1_009818 CC1CCN(CC1)c2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O07 compound treatment 743604.0 148000.0 0.66 642873.0 49600.0 0.25 0.6413 0.9089 1974701 ChemDiv1_009819 OS(=O)(=O)CCN1C(=O)/C(=C\2/C(=O)N(CC=C)c3ccc(Br)cc23)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O08 compound treatment 685128.0 89300.0 0.4 588066.0 -5250.0 -0.03 0.2642 0.6597 1473453 ChemDiv1_009820 COC(=O)c1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O09 compound treatment 684613.0 88800.0 0.4 600728.0 7410.0 0.04 0.307 0.7691 1974702 ChemDiv1_009821 Cc1ccc(CN2C(=O)/C(=C/3\SC(=S)N(CCS(=O)(=O)O)C3=O)/c4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O10 compound treatment 633789.0 38000.0 0.17 583034.0 -10300.0 -0.05 0.0841 0.4742 1974703 ChemDiv1_009822 COc1ccc(cc1)n2cccc2/C=C\3/NC(=O)NC3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O11 compound treatment 692270.0 96400.0 0.43 600376.0 7060.0 0.03 0.33 0.7619 1411395 ChemDiv1_009823 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(OC)c3)c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O12 compound treatment 653174.0 57300.0 0.26 580948.0 -12400.0 -0.06 0.1382 0.5235 1393388 ChemDiv1_009824 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3sc4nc5CCCc5cc4c3N)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O13 compound treatment 711544.0 116000.0 0.52 603685.0 10400.0 0.05 0.4026 0.7734 1736615 ChemDiv1_009825 COc1ccc(cc1F)c2cn3cc(Cl)ccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O14 compound treatment 676860.0 81000.0 0.36 577427.0 -15900.0 -0.08 0.2008 0.541 1974704 ChemDiv1_009826 COc1ccc(cc1)C(=O)COC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O15 compound treatment 703055.0 107000.0 0.48 614792.0 21500.0 0.11 0.4146 0.8434 1481834 ChemDiv1_009827 Nc1c(oc2ccccc12)C(=O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O16 compound treatment 663825.0 68000.0 0.3 577254.0 -16100.0 -0.08 0.1589 0.5052 1401846 ChemDiv1_009828 Fc1cc(C#N)ccc1C(=O)Nc2cc(ccc2Cl)c3nc4ncccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O17 compound treatment 708445.0 113000.0 0.5 609482.0 16200.0 0.08 0.4131 0.8093 1974705 ChemDiv1_009829 CCOC(=O)c1c(oc2ccc(OCc3ccc(Br)cc3)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O18 compound treatment 690106.0 94300.0 0.42 597643.0 4320.0 0.02 0.3135 0.742 1974706 ChemDiv1_009830 COCc1c(C#N)c(Nc2cccc(c2)C(F)(F)F)nc(C)c1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O19 compound treatment 700565.0 105000.0 0.47 601938.0 8620.0 0.04 0.3617 0.7683 1974707 ChemDiv1_009831 Fc1ccc(cc1)C(=O)CSc2ncn[nH]2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O20 compound treatment 539697.0 -56100.0 -0.25 474847.0 -118000.0 -0.59 -0.5927 -0.9284 1467951 ChemDiv1_009832 COc1ccc(cc1)c2cc(c(C#N)c(n2)S(=O)C)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O21 compound treatment 696201.0 100000.0 0.45 598388.0 5070.0 0.03 0.3354 0.7455 1864032 ChemDiv1_009833 COc1ccccc1Nc2nc(nc3ccccc23)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O22 compound treatment 677502.0 81700.0 0.37 584872.0 -8450.0 -0.04 0.2289 0.6221 1173840 ChemDiv1_009834 OC(CSc1nc2CCCCc2cc1C#N)CS(=O)(=O)Cc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O23 mock treatment 665157.0 69300.0 0.31 591317.0 -2000.0 -0.01 0.2124 0.6841 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 O24 mock treatment 227467.0 -368000.0 -1.65 414567.0 -179000.0 -0.89 -1.7921 -0.9575 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P01 compound treatment 523681.0 -72200.0 -0.32 498653.0 -94700.0 -0.47 -0.56 -0.9834 1249918 ChemDiv1_009835 COc1ccc(OC)c(NC(=O)C2=C(C)NC(=O)NC2c3ccc(Cl)cc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P02 compound treatment 564068.0 -31800.0 -0.14 521618.0 -71700.0 -0.36 -0.3517 -0.9193 1852885 ChemDiv1_009836 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Br)cc3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P03 compound treatment 594992.0 -844.0 0.0 534995.0 -58300.0 -0.29 -0.207 -0.7163 1684540 ChemDiv1_009837 CCOC(=O)c1ccc(Oc2nc(OC)nc(n2)N(C)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P04 compound treatment 589222.0 -6610.0 -0.03 530521.0 -62800.0 -0.31 -0.2409 -0.7709 1852889 ChemDiv1_009838 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(OC)cc3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P05 compound treatment 598614.0 2780.0 0.01 530387.0 -62900.0 -0.31 -0.2117 -0.6784 1974708 ChemDiv1_009839 NC(=O)C1NCCc2c1[nH]c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P06 compound treatment 621985.0 26100.0 0.12 561916.0 -31400.0 -0.16 -0.0272 -0.1399 1461315 ChemDiv1_009840 COc1cc(ccc1OCc2ccccc2)C3C(=C(N)N(N(C)C)C4=C3C(=O)CCC4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P07 compound treatment 607735.0 11900.0 0.05 550779.0 -42500.0 -0.21 -0.1114 -0.5123 1377057 ChemDiv1_009841 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cc(OC)ccc3OC)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P08 compound treatment 612446.0 16600.0 0.07 543760.0 -49600.0 -0.25 -0.121 -0.4718 1974709 ChemDiv1_009842 CCc1cc2c(=O)n(CC=C)c(SCC(=O)Nc3ccc(C)cc3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P09 compound treatment 615116.0 19300.0 0.09 546514.0 -46800.0 -0.23 -0.1029 -0.416 1852825 ChemDiv1_009843 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3OC)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P10 compound treatment 624323.0 28500.0 0.13 564874.0 -28400.0 -0.14 -0.0095 -0.0498 1974710 ChemDiv1_009844 CCc1cc2c(=O)n(CC=C)c(SCC(=O)c3cccs3)nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P11 compound treatment 612710.0 16900.0 0.08 540501.0 -52800.0 -0.26 -0.1316 -0.4832 1852836 ChemDiv1_009845 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(cc3)N(CC)CC)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P12 compound treatment 615532.0 19700.0 0.09 546706.0 -46600.0 -0.23 -0.1009 -0.4084 1647041 ChemDiv1_009846 Cc1ccccc1Nc2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P13 compound treatment 617360.0 21500.0 0.1 551632.0 -41700.0 -0.21 -0.0779 -0.3418 1852842 ChemDiv1_009847 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(Cl)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P14 compound treatment 577143.0 -18700.0 -0.08 529150.0 -64200.0 -0.32 -0.2839 -0.8638 1313914 ChemDiv1_009848 CCOc1ccc(Nc2nc(NCc3ccco3)c4ccccc4n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P15 compound treatment 632501.0 36700.0 0.16 547674.0 -45600.0 -0.23 -0.0438 -0.1569 1852849 ChemDiv1_009849 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccccc3C)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P16 compound treatment 624186.0 28400.0 0.13 559307.0 -34000.0 -0.17 -0.0294 -0.1394 1974711 ChemDiv1_009850 Cc1sc2ncnc(SCC(=O)c3ccc(Br)cc3)c2c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P17 compound treatment 624739.0 28900.0 0.13 558869.0 -34500.0 -0.17 -0.0292 -0.1363 1852856 ChemDiv1_009851 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(O)c(OC)c3)C1=O)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P18 compound treatment 618152.0 22300.0 0.1 575000.0 -18300.0 -0.09 0.0065 0.0479 1974712 ChemDiv1_009852 COc1cc(/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccc(cc3)S(=O)(=O)N)ccc1OCc4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P19 compound treatment 630278.0 34400.0 0.15 560045.0 -33300.0 -0.16 -0.0075 -0.0334 1852871 ChemDiv1_009853 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3cccc(Br)c3)C1=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P20 compound treatment 588712.0 -7120.0 -0.03 564739.0 -28600.0 -0.14 -0.1227 -0.8452 1974713 ChemDiv1_009854 Fc1ccccc1/C=C\2/SC(=O)N(CCNC3=NS(=O)(=O)c4ccccc34)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P21 compound treatment 621504.0 25700.0 0.11 558766.0 -34600.0 -0.17 -0.0398 -0.193 1852877 ChemDiv1_009855 CCOC(=O)C1C(CC2=C(C(C(=C(C)N2)C(=O)OCC)c3ccc(SC)cc3)C1=O)c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P22 compound treatment 600645.0 4810.0 0.02 560015.0 -33300.0 -0.16 -0.1014 -0.6097 1974714 ChemDiv1_009856 COc1cccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c1OCc4c(F)cccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P23 mock treatment 589672.0 -6160.0 -0.03 562480.0 -30800.0 -0.15 -0.1275 -0.8215 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.614 P24 mock treatment 266987.0 -329000.0 -1.47 453061.0 -140000.0 -0.69 -1.5322 -0.9413 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A01 compound treatment 591324.0 18900.0 0.08 598347.0 52500.0 0.26 0.2436 0.8913 1540529 ChemDiv1_009857 COc1ccc(cc1OCc2ccc(cc2)C(=O)OCC(C)C)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A02 compound treatment 590123.0 17700.0 0.08 589254.0 43400.0 0.21 0.2079 0.9081 1974715 ChemDiv1_009858 CCCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A03 compound treatment 616749.0 44300.0 0.2 615854.0 70000.0 0.35 0.3854 0.965 1308677 ChemDiv1_009859 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A04 compound treatment 629254.0 56800.0 0.25 621981.0 76100.0 0.38 0.4464 0.9817 1124923 ChemDiv1_009860 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A05 compound treatment 644625.0 72200.0 0.32 636725.0 90800.0 0.45 0.5467 0.9868 1974716 ChemDiv1_009861 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A06 compound treatment 659807.0 87400.0 0.39 649183.0 103000.0 0.51 0.6384 0.9912 1370242 ChemDiv1_009862 CCOc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(oc3c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A07 compound treatment 704982.0 133000.0 0.59 669105.0 123000.0 0.61 0.8512 0.9999 1724541 ChemDiv1_009863 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)c(Cl)c3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A08 compound treatment 701094.0 129000.0 0.58 681180.0 135000.0 0.67 0.8812 0.9972 1449876 ChemDiv1_009864 COCc1oc2c(cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)c1C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A09 compound treatment 1762691.0 1190000.0 5.33 1686670.0 1140000.0 5.65 7.7635 0.9996 1974717 ChemDiv1_009865 O=C/1N(CC2CCCO2)C(=S)S\C1=C/c3c(NCCCn4ccnc4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A10 compound treatment 664511.0 92100.0 0.41 661006.0 115000.0 0.57 0.6947 0.9873 1286371 ChemDiv1_009866 COc1cccc(OC)c1OCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A11 compound treatment 2179078.0 1610000.0 7.19 2028955.0 1480000.0 7.35 10.2805 0.9999 1974718 ChemDiv1_009867 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c(NCCc4ccccc4)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A12 compound treatment 677174.0 105000.0 0.47 653303.0 107000.0 0.53 0.7078 0.998 1974719 ChemDiv1_009868 CC(C)CN1C(=O)/C(=C/c2cn(nc2c3ccc(cc3)S(=O)(=O)N(C)C)c4ccccc4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A13 compound treatment 1182497.0 610000.0 2.73 1145324.0 599000.0 2.97 4.0308 0.9991 1974720 ChemDiv1_009869 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCCCC(=O)O)C3=O)c(nc12)N4CCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A14 compound treatment 697692.0 125000.0 0.56 657151.0 111000.0 0.55 0.7862 1.0 1974721 ChemDiv1_009870 CCOc1ccc(cc1)c2nn(cc2C3C(=C(C)NC(=C3C(=O)OCCOC)C)C(=O)OCCOC)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A15 compound treatment 697666.0 125000.0 0.56 647615.0 102000.0 0.5 0.7528 0.9986 1462514 ChemDiv1_009871 CCCn1nc(Oc2nc(nc(n2)N(C)C)N(C)C)ccc1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A16 compound treatment 679516.0 107000.0 0.48 633859.0 88000.0 0.44 0.6471 0.9989 1974722 ChemDiv1_009872 CCCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(C)cc3)C2=O)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A17 compound treatment 697415.0 125000.0 0.56 634961.0 89100.0 0.44 0.7076 0.9931 1480335 ChemDiv1_009873 OC1(CC(=O)c2ccc3CCc4cccc2c43)C(=O)N(CC#C)c5ccccc51 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A18 compound treatment 688191.0 116000.0 0.52 624137.0 78200.0 0.39 0.6405 0.9898 1742793 ChemDiv1_009874 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)S(=O)(=O)N4CCOCC4)c5ccccc5)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A19 compound treatment 667393.0 95000.0 0.43 629846.0 84000.0 0.42 0.5947 0.9999 1974723 ChemDiv1_009875 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A20 compound treatment 639260.0 66800.0 0.3 602867.0 57000.0 0.28 0.4111 0.9996 1974724 ChemDiv1_009876 COc1nc(cc(c1C#N)c2ccc(F)cc2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A21 compound treatment 638283.0 65900.0 0.29 612757.0 66900.0 0.33 0.4427 0.9983 1277738 ChemDiv1_009877 CCCc1oc2ccc(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A22 compound treatment 613650.0 41200.0 0.18 589406.0 43500.0 0.22 0.2829 0.997 1157713 ChemDiv1_009878 Cc1cccn2c(NC(=O)c3ccc(Br)cc3)c(nc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A23 mock treatment 591360.0 18900.0 0.08 573394.0 27500.0 0.14 0.1563 0.9739 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 A24 mock treatment 295232.0 -277000.0 -1.24 218391.0 -327000.0 -1.62 -2.0246 -0.9912 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B01 compound treatment 574401.0 1980.0 0.01 604404.0 58500.0 0.29 0.2112 0.7284 1925170 ChemDiv1_009879 CCOc1ccc(cc1[N+](=O)[O-])c2nn(cc2C3C(=C(C)NC(=C3C(=O)OC)C)C(=O)OC)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B02 compound treatment 614963.0 42500.0 0.19 630064.0 84200.0 0.42 0.4295 0.9369 1974725 ChemDiv1_009880 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B03 compound treatment 671953.0 99500.0 0.45 672928.0 127000.0 0.63 0.76 0.9857 1974726 ChemDiv1_009881 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OCC)c(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B04 compound treatment 651195.0 78800.0 0.35 681522.0 136000.0 0.67 0.7244 0.9547 1445050 ChemDiv1_009882 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B05 compound treatment 707064.0 135000.0 0.6 709633.0 164000.0 0.81 0.9997 0.9893 1277385 ChemDiv1_009883 CCCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B06 compound treatment 687809.0 115000.0 0.52 692658.0 147000.0 0.73 0.8793 0.986 1974727 ChemDiv1_009884 Cn1cnnc1SCC(=O)Nc2ccc(Br)c3cccnc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B07 compound treatment 743150.0 171000.0 0.76 734500.0 189000.0 0.93 1.2011 0.995 1134216 ChemDiv1_009885 CCOc1ccc(cc1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B08 compound treatment 718452.0 146000.0 0.65 717646.0 172000.0 0.85 1.0639 0.9915 1974728 ChemDiv1_009886 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B09 compound treatment 760873.0 188000.0 0.84 751978.0 206000.0 1.02 1.3184 0.9955 1974729 ChemDiv1_009887 Cc1ccc2nc(NC3=NC(CC(=O)N3)C(=O)Nc4ccc(Cl)c(Cl)c4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B10 compound treatment 732632.0 160000.0 0.72 740061.0 194000.0 0.96 1.1873 0.9895 1313139 ChemDiv1_009888 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B11 compound treatment 750644.0 178000.0 0.8 744159.0 198000.0 0.98 1.2586 0.9947 1974730 ChemDiv1_009889 NC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccc4ccccc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B12 compound treatment 735419.0 163000.0 0.73 734142.0 188000.0 0.93 1.1753 0.9926 1574996 ChemDiv1_009890 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)ccc3OC)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B13 compound treatment 740612.0 168000.0 0.75 723051.0 177000.0 0.88 1.1529 0.9971 1158240 ChemDiv1_009891 COc1ccc(cc1)c2cc(nc(SCC(=O)Nc3cc(C)on3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B14 compound treatment 735755.0 163000.0 0.73 701797.0 156000.0 0.77 1.0631 0.9996 1974731 ChemDiv1_009892 Clc1ccc(OCCNC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B15 compound treatment 756963.0 185000.0 0.83 680479.0 135000.0 0.67 1.0556 0.9944 1659786 ChemDiv1_009893 CN1C2CCC1CC(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5cc(Cl)cc(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B16 compound treatment 723045.0 151000.0 0.67 674824.0 129000.0 0.64 0.9284 0.9996 1160049 ChemDiv1_009894 O=C(CN1C(=O)c2ccccc2S1(=O)=O)N3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B17 compound treatment 748913.0 176000.0 0.79 694793.0 149000.0 0.74 1.0802 0.9994 1974732 ChemDiv1_009895 [O-][N+](=O)c1cccc(c1)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B18 compound treatment 791393.0 219000.0 0.98 690946.0 145000.0 0.72 1.2012 0.9883 1927412 ChemDiv1_009896 Brc1ccc(cc1)N2C(=O)/C(=C/c3ccc(o3)N4CCOCC4)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B19 compound treatment 716127.0 144000.0 0.64 649682.0 104000.0 0.51 0.8184 0.9938 1435088 ChemDiv1_009897 CC1C=CCC2C1C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B20 compound treatment 689707.0 117000.0 0.53 634711.0 88800.0 0.44 0.6824 0.9961 1974733 ChemDiv1_009898 CCCCOC(=O)c1ccc(cc1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B21 compound treatment 705549.0 133000.0 0.6 645440.0 99500.0 0.49 0.7701 0.9956 1786524 ChemDiv1_009899 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B22 compound treatment 663898.0 91500.0 0.41 609078.0 63200.0 0.31 0.5109 0.9912 1882550 ChemDiv1_009900 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B23 mock treatment 656186.0 83800.0 0.37 619604.0 73700.0 0.37 0.5233 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 B24 mock treatment 484625.0 -87800.0 -0.39 532162.0 -13700.0 -0.07 -0.326 -0.8173 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C01 compound treatment 581866.0 9440.0 0.04 628099.0 82200.0 0.41 0.3179 0.7763 1131715 ChemDiv1_009901 CC(=O)Oc1ccccc1c2nc3sc(=C4C(=O)N(CC(=O)N)c5ccccc45)c(=O)n3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C02 compound treatment 663629.0 91200.0 0.41 660983.0 115000.0 0.57 0.6918 0.9866 1974734 ChemDiv1_009902 CCCCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C03 compound treatment 718378.0 146000.0 0.65 720766.0 175000.0 0.87 1.0746 0.9903 1974735 ChemDiv1_009903 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C04 compound treatment 702902.0 130000.0 0.58 708216.0 162000.0 0.8 0.9816 0.9877 1237810 ChemDiv1_009904 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C05 compound treatment 1186144.0 614000.0 2.75 1189306.0 643000.0 3.19 4.1964 0.9973 1974736 ChemDiv1_009905 COCCCN1C(=O)/C(=C/c2c(NCCc3ccccc3)nc4ccccn4c2=O)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C06 compound treatment 731332.0 159000.0 0.71 724402.0 179000.0 0.88 1.1283 0.9942 1227226 ChemDiv1_009906 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C07 compound treatment 783386.0 211000.0 0.94 757700.0 212000.0 1.05 1.4097 0.9986 1974737 ChemDiv1_009907 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C08 compound treatment 758940.0 187000.0 0.83 747787.0 202000.0 1.0 1.2976 0.996 1123475 ChemDiv1_009908 Cc1oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc2c1C(=O)OCc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C09 compound treatment 965245.0 393000.0 1.76 955096.0 409000.0 2.03 2.6768 0.9975 1974738 ChemDiv1_009909 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccco4)C3=O)c(NCc5ccccc5)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C10 compound treatment 769970.0 198000.0 0.88 744596.0 199000.0 0.98 1.3213 0.9986 1974739 ChemDiv1_009910 COC(=O)c1ccc(OCCOCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C11 compound treatment 9435002.0 8860000.0 39.67 1.0183646E7 9640000.0 47.74 61.8123 0.9958 1974740 ChemDiv1_009911 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c(nc12)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C12 compound treatment 780868.0 208000.0 0.93 743701.0 198000.0 0.98 1.3527 0.9997 1974741 ChemDiv1_009912 CCCCN1C(=O)/C(=C/c2cn(nc2c3ccc(cc3)S(=O)(=O)N4CCOCC4)c5ccccc5)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C13 compound treatment 918351.0 346000.0 1.55 906631.0 361000.0 1.79 2.3586 0.9975 1974742 ChemDiv1_009913 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CCCCCC(=O)O)C3=O)c(NCCN4CCOCC4)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C14 compound treatment 725508.0 153000.0 0.69 721893.0 176000.0 0.87 1.1011 0.9929 1974743 ChemDiv1_009914 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccc(Cl)cc3)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C15 compound treatment 762352.0 190000.0 0.85 738249.0 192000.0 0.95 1.275 0.9984 1622245 ChemDiv1_009915 CN(C)c1nc(Oc2ccc(OCC(=O)N)nn2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C16 compound treatment 770861.0 198000.0 0.89 695499.0 150000.0 0.74 1.1522 0.9959 1974744 ChemDiv1_009916 CCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccc(C)cc3)C2=O)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C17 compound treatment 790317.0 218000.0 0.98 714167.0 168000.0 0.83 1.2791 0.9969 1133757 ChemDiv1_009917 CC(C(=O)c1ccccc1)C2(O)C(=O)N(CC#C)c3ccccc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C18 compound treatment 765139.0 193000.0 0.86 685337.0 139000.0 0.69 1.0985 0.9939 1925141 ChemDiv1_009918 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Cl)c3Cl)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C19 compound treatment 745182.0 173000.0 0.77 690705.0 145000.0 0.72 1.0541 0.9993 1257743 ChemDiv1_009919 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C20 compound treatment 722720.0 150000.0 0.67 637836.0 91900.0 0.46 0.7978 0.982 1185229 ChemDiv1_009920 COC(=O)c1sc(=S)n(CC=C)c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C21 compound treatment 739686.0 167000.0 0.75 672299.0 126000.0 0.63 0.9722 0.9961 1442214 ChemDiv1_009921 CCCc1oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C22 compound treatment 720880.0 148000.0 0.66 620696.0 74800.0 0.37 0.7319 0.962 1474080 ChemDiv1_009922 Cc1ccc2nc(c(NC(=O)c3ccco3)n2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C23 mock treatment 688879.0 116000.0 0.52 632451.0 86600.0 0.43 0.6718 0.9953 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 C24 mock treatment 535185.0 -37200.0 -0.17 411918.0 -134000.0 -0.66 -0.5872 -0.8581 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D01 compound treatment 599421.0 27000.0 0.12 607616.0 61700.0 0.31 0.3017 0.9175 1226085 ChemDiv1_009923 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(Br)c3)c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D02 compound treatment 640993.0 68600.0 0.31 648394.0 103000.0 0.51 0.5761 0.9709 1974745 ChemDiv1_009924 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D03 compound treatment 703440.0 131000.0 0.59 666264.0 120000.0 0.6 0.8364 1.0 1225503 ChemDiv1_009925 COC(=O)Nc1c(nc2ccc(Cl)cn12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D04 compound treatment 681411.0 109000.0 0.49 693175.0 147000.0 0.73 0.8609 0.9809 1680475 ChemDiv1_009926 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D05 compound treatment 708186.0 136000.0 0.61 725165.0 179000.0 0.89 1.0577 0.9829 1974746 ChemDiv1_009927 COc1cccc(c1)C(=O)N2C(C)CC(N(C(=O)CN3C(=O)c4ccccc4C3=O)c5ccccc5)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D06 compound treatment 702186.0 130000.0 0.58 717048.0 171000.0 0.85 1.0103 0.983 1974747 ChemDiv1_009928 COc1cc(ccc1OCc2c(F)cccc2Cl)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D07 compound treatment 743930.0 172000.0 0.77 740903.0 195000.0 0.97 1.226 0.9935 1585565 ChemDiv1_009929 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)c(OC)c4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D08 compound treatment 719513.0 147000.0 0.66 736254.0 190000.0 0.94 1.1324 0.9846 1974748 ChemDiv1_009930 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D09 compound treatment 758516.0 186000.0 0.83 761251.0 215000.0 1.07 1.3434 0.9925 1579917 ChemDiv1_009931 NC(=O)C1CCN(CC1)c2nc(Nc3ccccc3)nc(Nc4ccccc4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D10 compound treatment 819344.0 247000.0 1.11 773258.0 227000.0 1.13 1.578 1.0 1686102 ChemDiv1_009932 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(C)c4ccccc34)c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D11 compound treatment 781672.0 209000.0 0.94 800260.0 254000.0 1.26 1.5534 0.9893 1974749 ChemDiv1_009933 CC(=O)C1=C(C)OC(=C(C#N)C1c2cccs2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D12 compound treatment 949130.0 377000.0 1.69 942142.0 396000.0 1.96 2.5804 0.9971 1465178 ChemDiv1_009934 CCOC(=O)C1=C(C)N=c2sc(=Cc3cn(C)c4ccccc34)c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D13 compound treatment 736800.0 164000.0 0.74 747175.0 201000.0 1.0 1.2254 0.9888 1458654 ChemDiv1_009935 Cc1cc(NC(=O)CSc2nc3CCCc3c(c2C#N)c4cccnc4)no1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D14 compound treatment 713132.0 141000.0 0.63 727510.0 182000.0 0.9 1.0816 0.9848 1974750 ChemDiv1_009936 [O-][N+](=O)c1cccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D15 compound treatment 765771.0 193000.0 0.87 748466.0 203000.0 1.0 1.3216 0.9973 1974751 ChemDiv1_009937 COc1cc(/C=C\2/NC(=S)NC2=O)ccc1OC(=O)C3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D16 compound treatment 748152.0 176000.0 0.79 709054.0 163000.0 0.81 1.1278 0.9999 1974752 ChemDiv1_009938 CCN1C(=O)/C(=C/c2ccc(o2)c3cccc(Cl)c3C)/N(CC)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D17 compound treatment 781938.0 210000.0 0.94 722298.0 176000.0 0.87 1.2811 0.9994 1974753 ChemDiv1_009939 CC(C)C(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D18 compound treatment 760723.0 188000.0 0.84 672971.0 127000.0 0.63 1.0412 0.9897 1948457 ChemDiv1_009940 CCOC(=O)COc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cc(C)cc(C)c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D19 compound treatment 763776.0 191000.0 0.86 670528.0 125000.0 0.62 1.0423 0.9871 1974754 ChemDiv1_009941 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D20 compound treatment 732065.0 160000.0 0.71 659573.0 114000.0 0.56 0.9035 0.993 1974755 ChemDiv1_009942 Clc1ccc(cc1)C2SCC(=O)N2Nc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D21 compound treatment 739256.0 167000.0 0.75 666715.0 121000.0 0.6 0.9513 0.994 1226279 ChemDiv1_009943 Cc1ccc(cc1C)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D22 compound treatment 706034.0 134000.0 0.6 619759.0 73900.0 0.37 0.6817 0.9722 1974756 ChemDiv1_009944 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D23 mock treatment 677769.0 105000.0 0.47 626284.0 80400.0 0.4 0.6151 0.9965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 D24 mock treatment 494821.0 -77600.0 -0.35 499239.0 -46700.0 -0.23 -0.409 -0.9804 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E01 compound treatment 565887.0 -6540.0 -0.03 580239.0 34300.0 0.17 0.0996 0.577 1586734 ChemDiv1_009945 CC(=O)Oc1ccccc1c2nc3sc(=C4C(=O)N(CC=C)c5ccccc45)c(=O)n3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E02 compound treatment 680685.0 108000.0 0.48 671906.0 126000.0 0.62 0.7841 0.9922 1974757 ChemDiv1_009946 CCCCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E03 compound treatment 704813.0 132000.0 0.59 723284.0 177000.0 0.88 1.0404 0.9816 1974758 ChemDiv1_009947 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E04 compound treatment 712563.0 140000.0 0.63 717112.0 171000.0 0.85 1.0433 0.989 1332996 ChemDiv1_009948 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E05 compound treatment 1755251.0 1180000.0 5.29 1587170.0 1040000.0 5.16 7.3914 0.9999 1974759 ChemDiv1_009949 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCCCn4ccnc4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E06 compound treatment 723539.0 151000.0 0.68 747168.0 201000.0 1.0 1.1834 0.9821 1319511 ChemDiv1_009950 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E07 compound treatment 771965.0 200000.0 0.89 786457.0 241000.0 1.19 1.4743 0.9899 1974760 ChemDiv1_009951 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3cccs3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E08 compound treatment 763100.0 191000.0 0.85 773587.0 228000.0 1.13 1.4011 0.9905 1612085 ChemDiv1_009952 CC(C)(C)C1CCc2c(C1)sc3[nH]c(=S)n(C4CCCCC4)c(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E09 compound treatment 1817959.0 1250000.0 5.58 1754836.0 1210000.0 5.99 8.1772 0.9994 1974761 ChemDiv1_009953 COCCN1C(=O)/C(=C/c2c(NCCN3CCOCC3)nc4c(C)cccn4c2=O)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E10 compound treatment 762436.0 190000.0 0.85 735906.0 190000.0 0.94 1.267 0.9987 1974762 ChemDiv1_009954 COc1ccc(OCCOCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E11 compound treatment 762400.0 190000.0 0.85 784322.0 238000.0 1.18 1.4365 0.987 1974763 ChemDiv1_009955 CC1=C(C(NC(=O)N1)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E12 compound treatment 760088.0 188000.0 0.84 759298.0 213000.0 1.06 1.3415 0.9935 1642697 ChemDiv1_009956 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)cc3)c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E13 compound treatment 776907.0 204000.0 0.92 727521.0 182000.0 0.9 1.2835 1.0 1164137 ChemDiv1_009957 CCOc1ccc(cc1C)c2nn(cc2C3NC(=O)NC(=C3C(=O)OC)C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E14 compound treatment 810703.0 238000.0 1.07 800220.0 254000.0 1.26 1.6451 0.9966 1974764 ChemDiv1_009958 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccccc3[N+](=O)[O-])C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E15 compound treatment 791145.0 219000.0 0.98 743173.0 197000.0 0.98 1.3834 1.0 1974765 ChemDiv1_009959 Cn1c(=O)n(C)c2cc(/C=C\3/NC(=O)N(Cc4ccc(Br)cc4)C3=O)ccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E16 compound treatment 1.3096395E7 1.25E7 56.06 1.2588876E7 1.2E7 59.66 81.8268 0.9995 1974766 ChemDiv1_009960 CCN(CC)c1ccc(/C=C/2\SC(=S)N(C2=O)c3c(C)n(C)n(c4ccccc4)c3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E17 compound treatment 806940.0 235000.0 1.05 736228.0 190000.0 0.94 1.409 0.9986 1974767 ChemDiv1_009961 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(CC#C)c3ccccc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E18 compound treatment 750107.0 178000.0 0.8 704082.0 158000.0 0.78 1.1165 1.0 1925111 ChemDiv1_009962 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Br)c3)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E19 compound treatment 749448.0 177000.0 0.79 712484.0 167000.0 0.83 1.1439 0.9998 1640385 ChemDiv1_009963 CC(C)OC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E20 compound treatment 769736.0 197000.0 0.88 675614.0 130000.0 0.64 1.079 0.9878 1316457 ChemDiv1_009964 CCOC(=O)c1c(NC(=O)c2cc3ccccc3oc2=O)scc1c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E21 compound treatment 738226.0 166000.0 0.74 677749.0 132000.0 0.65 0.9867 0.998 1167327 ChemDiv1_009965 CCCc1oc2ccc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E22 compound treatment 710370.0 138000.0 0.62 655651.0 110000.0 0.54 0.8211 0.998 1215383 ChemDiv1_009966 Clc1ccc2nc(c(NC(=O)c3ccco3)n2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E23 mock treatment 693489.0 121000.0 0.54 639112.0 93200.0 0.46 0.7097 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 E24 mock treatment 524273.0 -48200.0 -0.22 219898.0 -326000.0 -1.61 -1.2943 -0.7944 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F01 compound treatment 606574.0 34200.0 0.15 601739.0 55800.0 0.28 0.3037 0.9609 1974768 ChemDiv1_009967 COc1ccc(cc1[N+](=O)[O-])c2nn(cc2C3C(=C(C)NC(=C3C(=O)OCC=C)C)C(=O)OCC=C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F02 compound treatment 642367.0 69900.0 0.31 643705.0 97800.0 0.48 0.564 0.9777 1851903 ChemDiv1_009968 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F03 compound treatment 681888.0 109000.0 0.49 705978.0 160000.0 0.79 0.9073 0.9732 1300294 ChemDiv1_009969 Cc1ccc(cc1)c2nc3ccc(C)cn3c2NC(=O)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F04 compound treatment 696146.0 124000.0 0.55 715596.0 170000.0 0.84 0.9861 0.9795 1974769 ChemDiv1_009970 O=C(COC(=O)c1ccc(cc1)N2C(=O)C3C(C4C=CC3C5CC54)C2=O)c6cccs6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F05 compound treatment 731139.0 159000.0 0.71 729822.0 184000.0 0.91 1.1467 0.9924 1401761 ChemDiv1_009971 Cn1cnnc1SCC(=O)n2c3CCCCc3c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F06 compound treatment 729547.0 157000.0 0.7 716943.0 171000.0 0.85 1.0965 0.9957 1974770 ChemDiv1_009972 Cc1n[nH]c2OC(=C(C#N)C(c12)c3cc(ccc3OCc4ccc(Br)cc4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F07 compound treatment 714992.0 143000.0 0.64 736080.0 190000.0 0.94 1.1175 0.982 1487696 ChemDiv1_009973 COc1ccc(Nc2nc(Cl)nc(Nc3ccc(OC)c(OC)c3)n2)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F08 compound treatment 765091.0 193000.0 0.86 746543.0 201000.0 0.99 1.3127 0.9975 1974771 ChemDiv1_009974 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F09 compound treatment 727829.0 155000.0 0.7 756773.0 211000.0 1.04 1.2306 0.9805 1974772 ChemDiv1_009975 COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(Sc4nncn4C)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F10 compound treatment 737200.0 165000.0 0.74 756074.0 210000.0 1.04 1.2578 0.9857 1229944 ChemDiv1_009976 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc(OC)c(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F11 compound treatment 773128.0 201000.0 0.9 779493.0 234000.0 1.16 1.4536 0.9922 1358551 ChemDiv1_009977 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F12 compound treatment 1240259.0 668000.0 2.99 1318172.0 772000.0 3.83 4.8191 0.9926 1727916 ChemDiv1_009978 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(Br)o4)c(=O)n23)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F13 compound treatment 751035.0 179000.0 0.8 753911.0 208000.0 1.03 1.294 0.9921 1974773 ChemDiv1_009979 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2C3CCN(CC3)C(=O)OCc4ccccc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F14 compound treatment 739046.0 167000.0 0.75 716958.0 171000.0 0.85 1.1266 0.998 1974774 ChemDiv1_009980 [O-][N+](=O)c1ccc(COc2ccc(C=C3C(=O)NC(=O)NC3=O)cc2Br)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F15 compound treatment 735974.0 164000.0 0.73 736670.0 191000.0 0.95 1.186 0.992 1262382 ChemDiv1_009981 OC(=O)c1cccc(Nc2nc(nc(n2)N3CCCC3)N4CCCC4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F16 compound treatment 758838.0 186000.0 0.83 721074.0 175000.0 0.87 1.2037 0.9998 1974775 ChemDiv1_009982 COc1cccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Br)cc3)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F17 compound treatment 774400.0 202000.0 0.9 732537.0 187000.0 0.92 1.2931 0.9999 1974776 ChemDiv1_009983 CC(C)C(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F18 compound treatment 745142.0 173000.0 0.77 684413.0 139000.0 0.69 1.0319 0.9982 1974777 ChemDiv1_009984 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(Cl)cc(OC)c3O)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F19 compound treatment 763529.0 191000.0 0.86 683477.0 138000.0 0.68 1.0868 0.9937 1178688 ChemDiv1_009985 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F20 compound treatment 744309.0 172000.0 0.77 648168.0 102000.0 0.51 0.9023 0.9795 1974778 ChemDiv1_009986 CC1SC(N(Nc2nc(nc(n2)N3CCOCC3)N4CCOCC4)C1=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F21 compound treatment 748448.0 176000.0 0.79 675259.0 129000.0 0.64 1.0103 0.9947 1623412 ChemDiv1_009987 CC(OC(=O)c1cccc(c1)N2C(=O)C3CC=CC(C)C3C2=O)C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F22 compound treatment 3736809.0 3160000.0 14.16 3220130.0 2670000.0 13.25 19.3837 0.9994 1974779 ChemDiv1_009988 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3O)[N+](=O)[O-])c(=O)n2C1c4ccc(SC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F23 mock treatment 686815.0 114000.0 0.51 632596.0 86700.0 0.43 0.6658 0.9962 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 F24 mock treatment 493031.0 -79400.0 -0.36 531628.0 -14300.0 -0.07 -0.3013 -0.8314 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G01 compound treatment 592264.0 19800.0 0.09 595613.0 49700.0 0.25 0.237 0.905 1303084 ChemDiv1_009989 CCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G02 compound treatment 670916.0 98500.0 0.44 666090.0 120000.0 0.6 0.7328 0.9891 1974780 ChemDiv1_009990 CCCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G03 compound treatment 670337.0 97900.0 0.44 711092.0 165000.0 0.82 0.8886 0.9572 1974781 ChemDiv1_009991 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G04 compound treatment 732242.0 160000.0 0.72 727275.0 181000.0 0.9 1.1412 0.9936 1323559 ChemDiv1_009992 COC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3ccc4NC(=O)c5cccc3c45)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G05 compound treatment 1438256.0 866000.0 3.88 1362456.0 817000.0 4.05 5.6009 0.9998 1974782 ChemDiv1_009993 COc1ccc(CCN2C(=O)/C(=C/c3c(nc4ccccn4c3=O)N5CCCCC5)/SC2=S)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G06 compound treatment 693086.0 121000.0 0.54 724882.0 179000.0 0.89 1.0089 0.9717 1182095 ChemDiv1_009994 COCc1oc2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2c1C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G07 compound treatment 1159683.0 587000.0 2.63 1096624.0 551000.0 2.73 3.788 0.9998 1974783 ChemDiv1_009995 COc1ccc(CCN2C(=O)/C(=C/c3c(NCc4ccccc4)nc5ccccn5c3=O)/SC2=S)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G08 compound treatment 734943.0 163000.0 0.73 735261.0 189000.0 0.94 1.1778 0.9921 1477911 ChemDiv1_009996 Cn1c(=O)c2c3CCCc3sc2n4c(SCC(=O)c5ccc(Br)cc5)nnc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G09 compound treatment 2048643.0 1480000.0 6.61 2006340.0 1460000.0 7.23 9.7884 0.999 1974784 ChemDiv1_009997 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)c(NCc5ccco5)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G10 compound treatment 764146.0 192000.0 0.86 742110.0 196000.0 0.97 1.2942 0.9981 1974785 ChemDiv1_009998 O=C(CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G11 compound treatment 777597.0 205000.0 0.92 763275.0 217000.0 1.08 1.4109 0.9969 1739114 ChemDiv1_009999 CCOc1ccc(cc1)c2nn(cc2C3NC(=O)NC(=C3C(=O)OCC=C)C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G12 compound treatment 725579.0 153000.0 0.69 714088.0 168000.0 0.83 1.074 0.9953 1974786 ChemDiv1_010000 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G13 compound treatment 765345.0 193000.0 0.86 729999.0 184000.0 0.91 1.2556 0.9996 1230133 ChemDiv1_010001 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G14 compound treatment 771589.0 199000.0 0.89 736299.0 190000.0 0.94 1.2974 0.9996 1974787 ChemDiv1_010002 Cc1c(N2C(=O)/C(=C/c3ccc(Br)cc3)/SC2=S)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G15 compound treatment 775508.0 203000.0 0.91 758261.0 212000.0 1.05 1.3867 0.9974 1974788 ChemDiv1_010003 COc1cc(/C=C\2/NC(=O)N(Cc3ccc(Br)cc3)C2=O)cc4OCOc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G16 compound treatment 913897.0 341000.0 1.53 869740.0 324000.0 1.6 2.2153 0.9997 1974789 ChemDiv1_010004 Clc1ccc(cc1)c2ccc(/C=C\3/NC(=S)N(C3=O)c4ccccc4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G17 compound treatment 771762.0 199000.0 0.89 713274.0 167000.0 0.83 1.2173 0.9993 1974790 ChemDiv1_010005 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(C)c3ccccc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G18 compound treatment 673576.0 101000.0 0.45 675950.0 130000.0 0.64 0.7758 0.9851 1925168 ChemDiv1_010006 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(Cl)c3)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G19 compound treatment 758439.0 186000.0 0.83 694613.0 149000.0 0.74 1.1097 0.9981 1927833 ChemDiv1_010007 COCCOC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G20 compound treatment 709409.0 137000.0 0.61 675850.0 130000.0 0.64 0.8888 0.9997 1924938 ChemDiv1_010008 Cc1ccn2c(NC(=O)/C=C/c3ccccc3)c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G21 compound treatment 730618.0 158000.0 0.71 672557.0 127000.0 0.63 0.9444 0.9982 1567944 ChemDiv1_010009 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(F)cc3)c4ccccc24)c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G22 compound treatment 721078.0 149000.0 0.67 646951.0 101000.0 0.5 0.8245 0.9902 1218183 ChemDiv1_010010 Clc1ccc2nc(c(NC(=O)c3cccs3)n2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G23 mock treatment 693569.0 121000.0 0.54 641637.0 95700.0 0.47 0.7188 0.9978 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 G24 mock treatment 453993.0 -118000.0 -0.53 514882.0 -31000.0 -0.15 -0.4835 -0.876 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H01 compound treatment 595169.0 22700.0 0.1 581400.0 35500.0 0.18 0.1964 0.9662 1974791 ChemDiv1_010011 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H02 compound treatment 642389.0 70000.0 0.31 621384.0 75500.0 0.37 0.4859 0.9961 1974792 ChemDiv1_010012 CC1CCC2C(C1)C(=O)N(C2=O)c3ccc(cc3)C(=O)OCC(=O)c4ccc(Cl)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H03 compound treatment 645155.0 72700.0 0.33 686903.0 141000.0 0.7 0.7242 0.9396 1585322 ChemDiv1_010013 CC(C)OC(=O)C1=C(C)N(C)C(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H04 compound treatment 649486.0 77100.0 0.34 668179.0 122000.0 0.61 0.6723 0.9644 1481161 ChemDiv1_010014 CC(C(=O)c1ccc(C)cc1)c2nc3ccccc3[nH]c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H05 compound treatment 713427.0 141000.0 0.63 714060.0 168000.0 0.83 1.0354 0.9906 1288485 ChemDiv1_010015 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)NC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H06 compound treatment 708039.0 136000.0 0.61 668077.0 122000.0 0.61 0.8573 1.0 1974793 ChemDiv1_010016 COc1ccc(C2C(=C(N)Oc3[nH]nc(C)c23)C#N)c(OCc4ccccc4Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H07 compound treatment 744935.0 173000.0 0.77 693669.0 148000.0 0.73 1.0637 0.9996 1974794 ChemDiv1_010017 CC1=CC(C)(C)N(C(=O)CSc2nncn2C)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H08 compound treatment 707655.0 135000.0 0.61 685927.0 140000.0 0.69 0.9186 0.9977 1974795 ChemDiv1_010018 COc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)ccc1Oc3nc(nc(n3)N4CCOCC4)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H09 compound treatment 692614.0 120000.0 0.54 732688.0 187000.0 0.93 1.0348 0.9667 1156629 ChemDiv1_010019 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H10 compound treatment 1125787.0 553000.0 2.48 1162757.0 617000.0 3.06 3.9124 0.9946 1142146 ChemDiv1_010020 CCOC(=O)C1=C(C)N=c2sc(=Cc3c[nH]c4ccccc34)c(=O)n2C1c5ccc(OC)c(OCC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H11 compound treatment 763160.0 191000.0 0.85 740396.0 195000.0 0.96 1.2851 0.9982 1974796 ChemDiv1_010021 CSc1nc(N)nc(SCCS(=O)(=O)c2ccc(C)cc2)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H12 compound treatment 1068662.0 496000.0 2.22 1005043.0 459000.0 2.27 3.1791 0.9999 1583216 ChemDiv1_010022 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cn(C)c5ccccc45)c(=O)n23)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H13 compound treatment 994886.0 422000.0 1.89 916771.0 371000.0 1.84 2.6364 0.9999 1216641 ChemDiv1_010023 COc1ccc(cc1)C(=O)c2sc3nc(ccc3c2N)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H14 compound treatment 717501.0 145000.0 0.65 711827.0 166000.0 0.82 1.0405 0.9932 1974797 ChemDiv1_010024 CCN1C(=O)C(=Cc2ccc(o2)c3cc(ccc3Cl)[N+](=O)[O-])C(=O)N(CC)C1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H15 compound treatment 791107.0 219000.0 0.98 727384.0 181000.0 0.9 1.3279 0.9991 1581583 ChemDiv1_010025 OC(=O)c1ccccc1Nc2nc(nc(n2)N3CCCC3)N4CCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H16 compound treatment 792627.0 220000.0 0.99 715146.0 169000.0 0.84 1.2899 0.9968 1974798 ChemDiv1_010026 CCOc1cccc(c1)N2C(=O)/C(=C\c3cc(Br)c(O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H17 compound treatment 772311.0 200000.0 0.89 699477.0 154000.0 0.76 1.1707 0.9967 1974799 ChemDiv1_010027 Brc1ccc(cc1)C(=O)COC(=O)C(CCCCN2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H18 compound treatment 1429856.0 857000.0 3.84 1227808.0 682000.0 3.38 5.1027 0.998 1974800 ChemDiv1_010028 COc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3cc(CC=C)c(O)c(OC)c3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H19 compound treatment 783857.0 211000.0 0.95 659812.0 114000.0 0.56 1.0683 0.9695 1974801 ChemDiv1_010029 CC(=O)c1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)cc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H20 compound treatment 690932.0 119000.0 0.53 644655.0 98800.0 0.49 0.7211 0.9992 1456964 ChemDiv1_010030 O=C1CSC(N1Nc2nc(nc(n2)N3CCCCC3)N4CCCCC4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H21 compound treatment 751200.0 179000.0 0.8 656570.0 111000.0 0.55 0.9536 0.983 1851890 ChemDiv1_010031 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccccc2N3C(=O)C4CC=CCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H22 compound treatment 720577.0 148000.0 0.66 639842.0 94000.0 0.47 0.798 0.985 1974802 ChemDiv1_010032 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H23 mock treatment 689362.0 117000.0 0.52 613002.0 67100.0 0.33 0.6052 0.976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 H24 mock treatment 484698.0 -87700.0 -0.39 496339.0 -49600.0 -0.25 -0.4512 -0.9744 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I01 compound treatment 580403.0 7980.0 0.04 570330.0 24400.0 0.12 0.1109 0.8783 1579586 ChemDiv1_010033 CCCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I02 compound treatment 656315.0 83900.0 0.38 659415.0 114000.0 0.56 0.6632 0.9807 1371161 ChemDiv1_010034 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I03 compound treatment 718058.0 146000.0 0.65 703317.0 157000.0 0.78 1.0124 0.996 1974803 ChemDiv1_010035 CC1=C(C(NC(=O)N1)c2cn(nc2c3cccs3)c4ccccc4)C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I04 compound treatment 675179.0 103000.0 0.46 711895.0 166000.0 0.82 0.9067 0.9623 1347857 ChemDiv1_010036 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I05 compound treatment 1578836.0 1010000.0 4.51 1464295.0 918000.0 4.55 6.4026 1.0 1974804 ChemDiv1_010037 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCc4ccco4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I06 compound treatment 711790.0 139000.0 0.62 690314.0 144000.0 0.72 0.947 0.9977 1599336 ChemDiv1_010038 COCc1oc2c(cc(NS(=O)(=O)c3c(C)cc(C)cc3C)c4ccccc24)c1C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I07 compound treatment 1232007.0 660000.0 2.95 1176726.0 631000.0 3.13 4.2975 0.9996 1974805 ChemDiv1_010039 O=C/1N(CC2CCCO2)C(=S)S\C1=C/c3c(NCc4ccccc4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I08 compound treatment 711937.0 140000.0 0.62 738486.0 193000.0 0.95 1.1162 0.9789 1974806 ChemDiv1_010040 COC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3ccccc3)NC(=O)OC(C)(C)C)C(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I09 compound treatment 1352657.0 780000.0 3.49 1310030.0 764000.0 3.79 5.1463 0.9992 1974807 ChemDiv1_010041 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(CC4CCCO4)C3=O)c(NCc5ccccc5)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I10 compound treatment 737504.0 165000.0 0.74 722055.0 176000.0 0.87 1.1396 0.9966 1543179 ChemDiv1_010042 COC(=O)CSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I11 compound treatment 739250.0 167000.0 0.75 756595.0 211000.0 1.04 1.2661 0.9865 1286147 ChemDiv1_010043 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(Cl)cc3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I12 compound treatment 745125.0 173000.0 0.77 730391.0 185000.0 0.91 1.1929 0.9965 1654349 ChemDiv1_010044 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I13 compound treatment 745004.0 173000.0 0.77 726700.0 181000.0 0.9 1.1796 0.9973 1283870 ChemDiv1_010045 O=C1CCCC2=C1C(C#Cc3ccccc3)C4=C(CCCC4=O)O2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I14 compound treatment 729447.0 157000.0 0.7 733969.0 188000.0 0.93 1.1558 0.9903 1974808 ChemDiv1_010046 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I15 compound treatment 756198.0 184000.0 0.82 755676.0 210000.0 1.04 1.3165 0.9933 1974809 ChemDiv1_010047 COc1cc(/C=C\2/NC(=O)NC2=O)cc(Cl)c1OCc3cccc(c3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I16 compound treatment 763263.0 191000.0 0.85 690195.0 144000.0 0.71 1.1095 0.9961 1974810 ChemDiv1_010048 CCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3Cl)C2=O)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I17 compound treatment 794821.0 222000.0 1.0 730468.0 185000.0 0.91 1.3505 0.9991 1974811 ChemDiv1_010049 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I18 compound treatment 755801.0 183000.0 0.82 687549.0 142000.0 0.7 1.0767 0.997 1684052 ChemDiv1_010050 O=C1CSC(N1Cc2cccnc2)c3cn(nc3c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I19 compound treatment 796955.0 225000.0 1.01 711040.0 165000.0 0.82 1.2892 0.9948 1974812 ChemDiv1_010051 COCCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c3cc(Cl)ccc3Cl)c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I20 compound treatment 734254.0 162000.0 0.72 643331.0 97400.0 0.48 0.8536 0.9805 1974813 ChemDiv1_010052 O=C(Nc1c(nc2ccccn12)c3ccccc3)/C=C/c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I21 compound treatment 742561.0 170000.0 0.76 682660.0 137000.0 0.68 1.0176 0.9983 1295632 ChemDiv1_010053 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24)c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I22 compound treatment 727659.0 155000.0 0.69 635789.0 89900.0 0.45 0.8063 0.9769 1379042 ChemDiv1_010054 CCC(=O)Nc1c(nc2cc(C)ccn12)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I23 mock treatment 696946.0 125000.0 0.56 637259.0 91400.0 0.45 0.7142 0.9947 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 I24 mock treatment 397744.0 -175000.0 -0.78 297012.0 -249000.0 -1.23 -1.4247 -0.9759 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J01 compound treatment 598098.0 25700.0 0.11 581642.0 35800.0 0.18 0.2065 0.9781 1974814 ChemDiv1_010055 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3cccc(c3)[N+](=O)[O-])c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J02 compound treatment 660512.0 88100.0 0.39 624666.0 78800.0 0.39 0.5548 1.0 1974815 ChemDiv1_010056 COc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4CC=CCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J03 compound treatment 681825.0 109000.0 0.49 657241.0 111000.0 0.55 0.7363 0.9982 1686757 ChemDiv1_010057 O=C(Nc1c(nc2ccccn12)c3ccccc3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J04 compound treatment 674466.0 102000.0 0.46 655762.0 110000.0 0.54 0.7079 0.9962 1974816 ChemDiv1_010058 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J05 compound treatment 695885.0 123000.0 0.55 661912.0 116000.0 0.57 0.7972 0.9998 1944355 ChemDiv1_010059 COc1ccc2N(C(=O)c3sc4cc(ccc4c3Cl)[N+](=O)[O-])C(C)(C)CC(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J06 compound treatment 693728.0 121000.0 0.54 678918.0 133000.0 0.66 0.8499 0.9954 1974817 ChemDiv1_010060 Cc1n[nH]c2OC(=C(C#N)C(c12)c3cc(ccc3OCc4cccc(F)c4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J07 compound treatment 752253.0 180000.0 0.8 733556.0 188000.0 0.93 1.2266 0.9974 1380461 ChemDiv1_010061 CC1=CC(C)(C)N(C(=O)CSc2nc3ccccc3[nH]2)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J08 compound treatment 707806.0 135000.0 0.61 691511.0 146000.0 0.72 0.9386 0.9962 1974818 ChemDiv1_010062 [O-][N+](=O)c1ccc(COc2ccc(Br)cc2C=C3C(=O)NC(=O)NC3=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J09 compound treatment 743214.0 171000.0 0.76 721456.0 176000.0 0.87 1.1556 0.9979 1974819 ChemDiv1_010063 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3nc(cs3)c4cccc(c4)[N+](=O)[O-])C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J10 compound treatment 714520.0 142000.0 0.64 680638.0 135000.0 0.67 0.9218 0.9997 1182288 ChemDiv1_010064 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccs3)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J11 compound treatment 874913.0 302000.0 1.35 839579.0 294000.0 1.45 1.9862 0.9994 1187818 ChemDiv1_010065 COc1ccc(cc1)C(=O)c2sc3nc(C)cc(c4cccs4)c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J12 compound treatment 886823.0 314000.0 1.41 826482.0 281000.0 1.39 1.978 1.0 1353044 ChemDiv1_010066 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4c[nH]c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J13 compound treatment 726858.0 154000.0 0.69 705740.0 160000.0 0.79 1.0488 0.9977 1974820 ChemDiv1_010067 CCc1nc2sc(C(=O)Nc3cccc(c3)C(F)(F)F)c(N)c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J14 compound treatment 737363.0 165000.0 0.74 655994.0 110000.0 0.55 0.9078 0.9889 1974821 ChemDiv1_010068 OC(=O)c1ccc(Cl)c(c1)c2ccc(/C=C/3\C(=O)NC(=O)N(C3=O)c4ccc5OCOc5c4)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J15 compound treatment 777897.0 205000.0 0.92 693788.0 148000.0 0.73 1.1684 0.9936 1974822 ChemDiv1_010069 O=C1C2CCCCC2C(=O)N1CN3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J16 compound treatment 720755.0 148000.0 0.66 687863.0 142000.0 0.7 0.9668 0.9996 1946651 ChemDiv1_010070 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J17 compound treatment 746243.0 174000.0 0.78 694363.0 148000.0 0.74 1.0703 0.9996 1675595 ChemDiv1_010071 Clc1ccc(cc1)C(=O)COC(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J18 compound treatment 955995.0 384000.0 1.72 869426.0 324000.0 1.6 2.3474 0.9994 1946335 ChemDiv1_010072 CCOc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccc(Br)o3)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J19 compound treatment 758594.0 186000.0 0.83 654863.0 109000.0 0.54 0.971 0.9779 1525783 ChemDiv1_010073 Cc1ccc2nc(cc(C(=O)N3CCOCC3)c2c1)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J20 compound treatment 731487.0 159000.0 0.71 648285.0 102000.0 0.51 0.8622 0.9862 1974823 ChemDiv1_010074 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccn3c4cccc(c4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)c(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J21 compound treatment 743649.0 171000.0 0.77 651353.0 105000.0 0.52 0.9114 0.9825 1851892 ChemDiv1_010075 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J22 compound treatment 722261.0 150000.0 0.67 622249.0 76400.0 0.38 0.7418 0.9633 1974824 ChemDiv1_010076 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J23 mock treatment 690246.0 118000.0 0.53 640283.0 94400.0 0.47 0.7036 0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 J24 mock treatment 538189.0 -34200.0 -0.15 528113.0 -17800.0 -0.09 -0.1706 -0.9654 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K01 compound treatment 564590.0 -7830.0 -0.04 553655.0 7760.0 0.04 0.0024 0.0461 1232023 ChemDiv1_010077 CCCCN1C(=O)C(=c2sc3nc(nn3c2=O)c4ccccc4OC(=O)C)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K02 compound treatment 654197.0 81800.0 0.37 624371.0 78500.0 0.39 0.5337 0.9995 1286841 ChemDiv1_010078 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3c(C)cc(C)cc3C)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K03 compound treatment 684967.0 113000.0 0.5 657739.0 112000.0 0.55 0.748 0.9989 1974825 ChemDiv1_010079 COCCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K04 compound treatment 673402.0 101000.0 0.45 657873.0 112000.0 0.55 0.7119 0.9948 1378602 ChemDiv1_010080 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(C)cc3C)c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K05 compound treatment 1243536.0 671000.0 3.0 1085559.0 540000.0 2.67 4.0146 0.9983 1974826 ChemDiv1_010081 COc1ccc(CCN2C(=O)/C(=C/c3c(NCCO)nc4ccccn4c3=O)/SC2=S)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K06 compound treatment 715443.0 143000.0 0.64 685244.0 139000.0 0.69 0.9408 0.9993 1429400 ChemDiv1_010082 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(COC)oc3c4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K07 compound treatment 1819502.0 1250000.0 5.58 1700134.0 1150000.0 5.72 7.9905 0.9999 1974827 ChemDiv1_010083 COCCN1C(=O)/C(=C/c2c(NCCCn3ccnc3)nc4ccccn4c2=O)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K08 compound treatment 736125.0 164000.0 0.73 678932.0 133000.0 0.66 0.9842 0.9986 1974828 ChemDiv1_010084 CC(C)N1C(=O)C2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K09 compound treatment 1353397.0 781000.0 3.5 1185517.0 640000.0 3.17 4.7125 0.9988 1974829 ChemDiv1_010085 Cc1cccn2c(=O)c(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)c(NCCN5CCOCC5)nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K10 compound treatment 713211.0 141000.0 0.63 673252.0 127000.0 0.63 0.8918 1.0 1940859 ChemDiv1_010086 C=CCn1c(SCC(=O)N2CCOCC2)nc3sc4CCCCc4c3c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K11 compound treatment 737595.0 165000.0 0.74 722304.0 176000.0 0.87 1.1408 0.9965 1701250 ChemDiv1_010087 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(Br)cc3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K12 compound treatment 690705.0 118000.0 0.53 693479.0 148000.0 0.73 0.8914 0.9874 1312521 ChemDiv1_010088 CCOC(=O)C1=C(C)NC(=C(C1c2ccc(OC(=O)c3ccc(C)cc3)c(OC)c2)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K13 compound treatment 706406.0 134000.0 0.6 701063.0 155000.0 0.77 0.9676 0.9925 1311469 ChemDiv1_010089 CCNc1nc(NC(C)C)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K14 compound treatment 703830.0 131000.0 0.59 682129.0 136000.0 0.67 0.8932 0.9977 1558025 ChemDiv1_010090 CCOc1ccc(cc1)c2nn(cc2C3C(=C(C)NC(=C3C(=O)OC)C)C(=O)OC)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K15 compound treatment 750568.0 178000.0 0.8 725236.0 179000.0 0.89 1.1921 0.9985 1974830 ChemDiv1_010091 Clc1ccc(Sc2oc(/C=C\3/NC(=O)NC3=O)cc2Br)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K16 compound treatment 704760.0 132000.0 0.59 693345.0 147000.0 0.73 0.9354 0.9946 1974831 ChemDiv1_010092 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3C(C=C(Cl)Cl)C3(C)C)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K17 compound treatment 741699.0 169000.0 0.76 692514.0 147000.0 0.73 1.0494 0.9998 1304552 ChemDiv1_010093 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2cc(O)ccc2O)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K18 compound treatment 717149.0 145000.0 0.65 683768.0 138000.0 0.68 0.9411 0.9997 1974832 ChemDiv1_010094 COc1nc(cc(c1C#N)c2cccc(c2)[N+](=O)[O-])c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K19 compound treatment 705709.0 133000.0 0.6 676291.0 130000.0 0.65 0.8787 0.9992 1677350 ChemDiv1_010095 CCCc1oc2ccc(NS(=O)(=O)c3ccc(Br)cc3)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K20 compound treatment 721748.0 149000.0 0.67 635542.0 89700.0 0.44 0.7867 0.9803 1483656 ChemDiv1_010096 CCC(=O)Nc1c(nc2ccc(C)cn12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K21 compound treatment 710789.0 138000.0 0.62 649183.0 103000.0 0.51 0.7998 0.9955 1412753 ChemDiv1_010097 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(OCC)cc3)c4ccccc24)c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K22 compound treatment 692717.0 120000.0 0.54 629353.0 83500.0 0.41 0.6731 0.9915 1134589 ChemDiv1_010098 CCC(=O)Nc1c(nc2ccc(C)cn12)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K23 mock treatment 679558.0 107000.0 0.48 621292.0 75400.0 0.37 0.6032 0.9924 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 K24 mock treatment 507164.0 -65300.0 -0.29 505950.0 -39900.0 -0.2 -0.3465 -0.982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L01 compound treatment 592868.0 20400.0 0.09 606345.0 60500.0 0.3 0.2765 0.8829 1974833 ChemDiv1_010099 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L02 compound treatment 653745.0 81300.0 0.36 591483.0 45600.0 0.23 0.4171 0.9736 1789122 ChemDiv1_010100 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)c2ccccc2N3C(=O)C4CC=CCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L03 compound treatment 677373.0 105000.0 0.47 638892.0 93000.0 0.46 0.658 1.0 1424870 ChemDiv1_010101 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1C(=O)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L04 compound treatment 747231.0 175000.0 0.78 659469.0 114000.0 0.56 0.9512 0.9869 1974834 ChemDiv1_010102 NS(=O)(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L05 compound treatment 691461.0 119000.0 0.53 640325.0 94400.0 0.47 0.7076 0.9979 1439504 ChemDiv1_010103 CCC(C)C(=O)N(C1CC(C)N(C(=O)C(C)CC)c2ccccc12)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L06 compound treatment 697490.0 125000.0 0.56 639630.0 93700.0 0.46 0.7242 0.9957 1974835 ChemDiv1_010104 COc1ccc(cc1OC)C2CC(=NN2c3nc(cs3)c4ccc(cc4)S(=O)(=O)N5CCOCC5)c6cccs6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L07 compound treatment 719858.0 147000.0 0.66 658578.0 113000.0 0.56 0.8614 0.9965 1704151 ChemDiv1_010105 COc1ccc2nc(NC(=O)CCN3C(=O)c4ccccc4C3=O)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L08 compound treatment 683753.0 111000.0 0.5 654881.0 109000.0 0.54 0.7342 0.9992 1209552 ChemDiv1_010106 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc(OC)c3OC)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L09 compound treatment 730032.0 158000.0 0.71 666618.0 121000.0 0.6 0.9218 0.9966 1974836 ChemDiv1_010107 NC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L10 compound treatment 1137010.0 565000.0 2.53 1090156.0 544000.0 2.7 3.6936 0.9995 1456980 ChemDiv1_010108 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(Br)o3)c(=O)n2C1c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L11 compound treatment 746849.0 174000.0 0.78 673139.0 127000.0 0.63 0.9978 0.9944 1974837 ChemDiv1_010109 COc1ccc(NC(=O)CSc2nc3CCN(C)Cc3c(c2C#N)c4ccccc4)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L12 compound treatment 1980232.0 1410000.0 6.3 1790135.0 1240000.0 6.16 8.8145 0.9999 1718555 ChemDiv1_010110 COc1cccc(c1)C2C(=C(C)N=c3sc(=Cc4cn(C)c5ccccc45)c(=O)n23)C(=O)Nc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L13 compound treatment 722104.0 150000.0 0.67 655851.0 110000.0 0.54 0.859 0.9947 1974838 ChemDiv1_010111 CC(CNC(=O)c1sc2ccccc2c1Cl)NC(=O)c3sc4ccccc4c3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L14 compound treatment 1226806.0 654000.0 2.93 769214.0 223000.0 1.11 2.8536 0.9113 1974839 ChemDiv1_010112 Clc1cccc(N2C(=O)/C(=C/c3ccc(o3)N4CCOCC4)/C(=O)NC2=S)c1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L15 compound treatment 763625.0 191000.0 0.86 680767.0 135000.0 0.67 1.0777 0.9925 1353875 ChemDiv1_010113 O=C(COC(=O)c1ccccc1N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L16 compound treatment 749705.0 177000.0 0.79 674197.0 128000.0 0.64 1.0106 0.9939 1925289 ChemDiv1_010114 COc1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L17 compound treatment 747353.0 175000.0 0.78 665235.0 119000.0 0.59 0.9717 0.9904 1271068 ChemDiv1_010115 O=C(COC(=O)c1cc(cc(c1)C(=O)OCC(=O)c2ccccc2)N3C(=O)C4CC=CCC4C3=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L18 compound treatment 719036.0 147000.0 0.66 626301.0 80400.0 0.4 0.7457 0.9714 1974840 ChemDiv1_010116 Fc1cc(Br)ccc1NC(=O)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L19 compound treatment 745390.0 173000.0 0.77 667190.0 121000.0 0.6 0.9724 0.9921 1226960 ChemDiv1_010117 Cc1ccc2nc(cc(C(=O)N3CCOCC3)c2c1)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L20 compound treatment 710982.0 139000.0 0.62 628304.0 82400.0 0.41 0.7273 0.9794 1882552 ChemDiv1_010118 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L21 compound treatment 732392.0 160000.0 0.72 644126.0 98200.0 0.49 0.8504 0.9823 1851893 ChemDiv1_010119 Cc1ccc(cc1[N+](=O)[O-])C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L22 compound treatment 693276.0 121000.0 0.54 617716.0 71800.0 0.36 0.6341 0.9793 1974841 ChemDiv1_010120 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L23 mock treatment 681796.0 109000.0 0.49 610713.0 64800.0 0.32 0.5733 0.9791 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 L24 mock treatment 507855.0 -64600.0 -0.29 534473.0 -11400.0 -0.06 -0.2444 -0.8297 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M01 compound treatment 587086.0 14700.0 0.07 607257.0 61400.0 0.3 0.2614 0.8404 1482348 ChemDiv1_010121 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M02 compound treatment 633859.0 61400.0 0.28 604344.0 58500.0 0.29 0.3992 0.9997 1974842 ChemDiv1_010122 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3cc(ccc3Cl)[N+](=O)[O-])cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M03 compound treatment 677921.0 105000.0 0.47 642372.0 96500.0 0.48 0.6719 1.0 1141356 ChemDiv1_010123 COC(=O)C1=C(C)N(C)C(=O)NC1c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M04 compound treatment 672305.0 99900.0 0.45 628856.0 83000.0 0.41 0.6068 0.9991 1524225 ChemDiv1_010124 CCc1ccc(cc1)S(=O)(=O)Nc2cc3c(C(=O)OC)c(oc3c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M05 compound treatment 695379.0 123000.0 0.55 657672.0 112000.0 0.55 0.7807 1.0 1695092 ChemDiv1_010125 COc1ccc(cc1)c2nn(cc2C3NC(=O)NC(=C3C(=O)OC(C)C)C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M06 compound treatment 712673.0 140000.0 0.63 662876.0 117000.0 0.58 0.8537 0.9992 1506896 ChemDiv1_010126 COCc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)cc3)c4ccccc24)c1C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M07 compound treatment 1095492.0 523000.0 2.34 995799.0 450000.0 2.23 3.2316 0.9997 1974843 ChemDiv1_010127 O=C/1N(Cc2ccco2)C(=S)S\C1=C/c3c(NCCc4ccccc4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M08 compound treatment 707697.0 135000.0 0.61 620904.0 75000.0 0.37 0.6909 0.9725 1616725 ChemDiv1_010128 COc1ccc(cc1)c2cc(C#N)nc(n2)N3CCN(CC3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M09 compound treatment 1972782.0 1400000.0 6.27 1790264.0 1240000.0 6.16 8.7914 1.0 1974844 ChemDiv1_010129 CC1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(CC5CCCO5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M10 compound treatment 684005.0 112000.0 0.5 645267.0 99400.0 0.49 0.7013 1.0 1701406 ChemDiv1_010130 COc1ccc(cc1OC)c2cn3cccc(C)c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M11 compound treatment 721850.0 149000.0 0.67 675869.0 130000.0 0.64 0.9283 0.9998 1232501 ChemDiv1_010131 COc1ccc(cc1Cl)c2nn(cc2C3NC(=O)NC(=C3C(=O)OCC=C)C)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M12 compound treatment 687863.0 115000.0 0.52 655963.0 110000.0 0.55 0.751 0.9996 1501090 ChemDiv1_010132 CC(C)OC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3cccs3)c4ccccc4)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M13 compound treatment 680758.0 108000.0 0.48 667504.0 122000.0 0.6 0.7689 0.9942 1140070 ChemDiv1_010133 CCNc1nc(NC(C)C)nc(Oc2ccc(OCC)nn2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M14 compound treatment 698161.0 126000.0 0.56 644685.0 98800.0 0.49 0.7441 0.9976 1974845 ChemDiv1_010134 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M15 compound treatment 710935.0 139000.0 0.62 678784.0 133000.0 0.66 0.9039 0.9996 1974846 ChemDiv1_010135 O=C1NC(=O)/C(=C\c2ccc(Sc3ccccc3)o2)/N1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M16 compound treatment 845079.0 273000.0 1.22 769988.0 224000.0 1.11 1.648 0.9989 1974847 ChemDiv1_010136 CCOc1ccc(cc1[N+](=O)[O-])c2nn(cc2/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M17 compound treatment 751060.0 179000.0 0.8 653475.0 108000.0 0.53 0.9423 0.9806 1529063 ChemDiv1_010137 CCOC(=O)CN1C(=O)C(O)(C(C)C(=O)c2ccccc2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M18 compound treatment 696051.0 124000.0 0.55 631028.0 85100.0 0.42 0.6895 0.991 1974848 ChemDiv1_010138 COc1nc(cc(c1C#N)c2ccc(cc2)C(C)C)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M19 compound treatment 663127.0 90700.0 0.41 644655.0 98800.0 0.49 0.6331 0.9957 1150047 ChemDiv1_010139 CCCc1oc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M20 compound treatment 706163.0 134000.0 0.6 611763.0 65900.0 0.33 0.6541 0.9593 1693108 ChemDiv1_010140 Cc1ccn2c(NC(=O)c3ccco3)c(nc2c1)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M21 compound treatment 742464.0 170000.0 0.76 643997.0 98100.0 0.49 0.8819 0.9765 1575724 ChemDiv1_010141 CCCc1oc2c(cc(NS(=O)(=O)c3cc(C)ccc3C)c4ccccc24)c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M22 compound treatment 685361.0 113000.0 0.51 612897.0 67000.0 0.33 0.5922 0.9792 1224427 ChemDiv1_010142 Cc1ccc(cc1)c2nc3ccc(C)cn3c2NC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M23 mock treatment 659411.0 87000.0 0.39 619429.0 73500.0 0.36 0.5329 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 M24 mock treatment 530241.0 -42200.0 -0.19 403386.0 -143000.0 -0.71 -0.6327 -0.8658 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N01 compound treatment 613263.0 40800.0 0.18 579671.0 33800.0 0.17 0.2476 0.999 1974849 ChemDiv1_010143 CC1=C(C(C(=C(C)N1)C(=O)OCC=C)c2cn(nc2c3ccco3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N02 compound treatment 640380.0 68000.0 0.3 579939.0 34000.0 0.17 0.3344 0.9613 1189545 ChemDiv1_010144 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N03 compound treatment 693195.0 121000.0 0.54 626537.0 80600.0 0.4 0.6648 0.9889 1172800 ChemDiv1_010145 CC(C)C(=O)N1C(C)CC(N(C(=O)c2ccc(F)cc2)c3ccccc3)c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N04 compound treatment 690764.0 118000.0 0.53 589082.0 43200.0 0.21 0.5259 0.9205 1312065 ChemDiv1_010146 NS(=O)(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)c3ccccc3)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N05 compound treatment 687863.0 115000.0 0.52 623851.0 78000.0 0.39 0.6385 0.9897 1322921 ChemDiv1_010147 COc1nc(Nc2nc3ccccc3c(=O)[nH]2)nc4ccc(C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N06 compound treatment 694048.0 122000.0 0.54 617672.0 71800.0 0.36 0.6364 0.9787 1974850 ChemDiv1_010148 CCN(CC)S(=O)(=O)c1ccc(cc1)c2csc(n2)N3N=C(CC3c4ccco4)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N07 compound treatment 692663.0 120000.0 0.54 606201.0 60300.0 0.3 0.5919 0.9614 1974851 ChemDiv1_010149 COc1ccc(Nc2nc(Cl)nc(Nc3ccc(OC)cc3OC)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N08 compound treatment 724870.0 152000.0 0.68 645569.0 99700.0 0.49 0.8317 0.9874 1305096 ChemDiv1_010150 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(OC)c(OC)c3)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N09 compound treatment 696755.0 124000.0 0.56 656084.0 110000.0 0.55 0.7795 1.0 1974852 ChemDiv1_010151 COC(=O)CSc1nc(cc(c2cccs2)c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N10 compound treatment 700117.0 128000.0 0.57 625241.0 79400.0 0.39 0.6821 0.9833 1149290 ChemDiv1_010152 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Cl)c(=O)n2C1c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N11 compound treatment 1042699.0 470000.0 2.11 938430.0 393000.0 1.94 2.8636 0.9992 1297767 ChemDiv1_010153 COc1ccc(cc1OC)C(=O)c2sc3nc(C)cc(c4cccs4)c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N12 compound treatment 706883.0 134000.0 0.6 611130.0 65200.0 0.32 0.6541 0.9575 1974853 ChemDiv1_010154 CN1C(=O)N(C)C(=O)C(=Cc2ccc(o2)c3ccc(C)cc3Br)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N13 compound treatment 706862.0 134000.0 0.6 657053.0 111000.0 0.55 0.8149 0.999 1697240 ChemDiv1_010155 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N14 compound treatment 677360.0 105000.0 0.47 632451.0 86600.0 0.43 0.6354 0.999 1974854 ChemDiv1_010156 CN(C1=NS(=O)(=O)c2ccccc12)c3ccc(OC(=O)C4CN(C(=O)C4)c5ccccc5)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N15 compound treatment 725302.0 153000.0 0.68 648337.0 102000.0 0.51 0.8428 0.9892 1464179 ChemDiv1_010157 O=C(COC(=O)c1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N16 compound treatment 714722.0 142000.0 0.64 626574.0 80700.0 0.4 0.733 0.9748 1974855 ChemDiv1_010158 CCN(CC)c1ccc(/C=C\2/C(=C(C#N)c3nc(N)c(C#N)c(C)c23)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N17 compound treatment 746112.0 174000.0 0.78 648377.0 102000.0 0.51 0.9088 0.9787 1974856 ChemDiv1_010159 Clc1ccc(cc1)C(=O)COC(=O)c2ccccc2N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N18 compound treatment 752969.0 181000.0 0.81 653365.0 107000.0 0.53 0.9479 0.9795 1417498 ChemDiv1_010160 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc(OC)c3O)c(=O)n2C1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N19 compound treatment 678207.0 106000.0 0.47 630208.0 84300.0 0.42 0.6302 0.998 1391216 ChemDiv1_010161 COc1ccc(cc1)c2cc(C(=O)N3CCOCC3)c4cc(C)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N20 compound treatment 702922.0 130000.0 0.58 614964.0 69100.0 0.34 0.655 0.9675 1882557 ChemDiv1_010162 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cc(OC)c(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N21 compound treatment 730441.0 158000.0 0.71 616036.0 70100.0 0.35 0.7459 0.9464 1851897 ChemDiv1_010163 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(C)c(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N22 compound treatment 624877.0 52500.0 0.23 599030.0 53100.0 0.26 0.3522 0.9984 1974857 ChemDiv1_010164 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(ccc3N4CCN(C)CC4)[N+](=O)[O-])c(=O)n2C1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N23 mock treatment 670319.0 97900.0 0.44 599514.0 53600.0 0.27 0.4977 0.9712 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 N24 mock treatment 414598.0 -158000.0 -0.71 405825.0 -140000.0 -0.69 -0.9902 -1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O01 compound treatment 596837.0 24400.0 0.11 577070.0 31200.0 0.15 0.1865 0.9856 1974858 ChemDiv1_010165 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(Br)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O02 compound treatment 601574.0 29200.0 0.13 570634.0 24700.0 0.12 0.1789 0.9995 1247959 ChemDiv1_010166 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3cc(C)ccc3C)cc12)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O03 compound treatment 665914.0 93500.0 0.42 598852.0 53000.0 0.26 0.4814 0.9747 1546645 ChemDiv1_010167 COC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)cc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O04 compound treatment 634543.0 62100.0 0.28 584804.0 38900.0 0.19 0.3329 0.984 1523252 ChemDiv1_010168 COC(=O)c1c(oc2c1cc(NS(=O)(=O)c3ccc(OC)cc3)c4ccccc24)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O05 compound treatment 675845.0 103000.0 0.46 626264.0 80400.0 0.4 0.6089 0.9972 1402904 ChemDiv1_010169 CCOC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC)c(Br)c3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O06 compound treatment 658726.0 86300.0 0.39 607708.0 61800.0 0.31 0.4897 0.9934 1203266 ChemDiv1_010170 COCc1oc2c(cc(NS(=O)(=O)c3ccc(Br)cc3)c4ccccc24)c1C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O07 compound treatment 1220600.0 648000.0 2.9 1092180.0 546000.0 2.71 3.9652 0.9994 1974859 ChemDiv1_010171 COCCCN1C(=O)/C(=C/c2c(NCCCn3ccnc3)nc4ccccn4c2=O)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O08 compound treatment 627042.0 54600.0 0.24 583552.0 37700.0 0.19 0.3048 0.9911 1974860 ChemDiv1_010172 COC(=O)c1ccccc1OCCCn2c(nc3ccccc3c2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O09 compound treatment 649997.0 77600.0 0.35 603282.0 57400.0 0.28 0.4466 0.9951 1586912 ChemDiv1_010173 CCOC(=O)C1=C(C)N=c2sc(=C3C(=O)N(CC=C)c4ccccc34)c(=O)n2C1c5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O10 compound treatment 621216.0 48800.0 0.22 587475.0 41600.0 0.21 0.3001 0.9996 1924477 ChemDiv1_010174 COCCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(F)cc3)c4ccccc4)C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O11 compound treatment 691348.0 119000.0 0.53 613973.0 68100.0 0.34 0.6149 0.9757 1552944 ChemDiv1_010175 CC1=C(C(NC(=O)N1)c2cn(nc2c3ccc(C)cc3)c4ccccc4)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O12 compound treatment 635119.0 62700.0 0.28 594813.0 48900.0 0.24 0.3698 0.9973 1974861 ChemDiv1_010176 COCCOC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3cccc(c3)[N+](=O)[O-])C(=O)OCCOC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O13 compound treatment 681975.0 110000.0 0.49 604851.0 59000.0 0.29 0.5533 0.9694 1974862 ChemDiv1_010177 CCNc1nc(NC(C)C)nc(Oc2ccc(OCCOc3ccccc3)nn2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O14 compound treatment 655513.0 83100.0 0.37 593412.0 47500.0 0.24 0.4295 0.9757 1974863 ChemDiv1_010178 CCOC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)[N+](=O)[O-])c4ccccc4)C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O15 compound treatment 679066.0 107000.0 0.48 599123.0 53200.0 0.26 0.524 0.9609 1974864 ChemDiv1_010179 [O-][N+](=O)c1ccc(COc2ccc3ccccc3c2/C=C\4/NC(=O)NC4=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O16 compound treatment 653038.0 80600.0 0.36 583937.0 38000.0 0.19 0.3884 0.9541 1974865 ChemDiv1_010180 COc1nc(cc(c1C#N)c2ccc(C)cc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O17 compound treatment 714743.0 142000.0 0.64 621868.0 76000.0 0.38 0.7166 0.9685 1238374 ChemDiv1_010181 CCOC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(OC)cc2OC)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O18 compound treatment 667822.0 95400.0 0.43 579859.0 34000.0 0.17 0.4209 0.9171 1032503 ChemDiv1_010182 COC(=O)CN1C(=O)c2ccccc2S1(=O)=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O19 compound treatment 665001.0 92600.0 0.41 605591.0 59700.0 0.3 0.5022 0.9863 1645934 ChemDiv1_010183 CCCc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3C)cc2c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O20 compound treatment 653457.0 81000.0 0.36 578823.0 32900.0 0.16 0.3719 0.9349 1734563 ChemDiv1_010184 COc1ccc(cc1)C(=O)Nc2c(nc3ccc(C)cn23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O21 compound treatment 654219.0 81800.0 0.37 600002.0 54100.0 0.27 0.4485 0.9883 1974866 ChemDiv1_010185 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(Cl)c(c3)[N+](=O)[O-])c4ccccc24)c1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O22 compound treatment 630760.0 58300.0 0.26 595334.0 49400.0 0.24 0.3578 0.9995 1336596 ChemDiv1_010186 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(cc3)S(=O)(=O)N(C)C)c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O23 mock treatment 636108.0 63700.0 0.29 592079.0 46200.0 0.23 0.3634 0.9941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 O24 mock treatment 175290.0 -397000.0 -1.78 419801.0 -126000.0 -0.62 -1.6987 -0.9015 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P01 compound treatment 560636.0 -11800.0 -0.05 532227.0 -13700.0 -0.07 -0.0852 -0.9924 1264656 ChemDiv1_010187 COC(=O)C1=C(C)NC(=C(C1c2cn(nc2c3ccc(OC)c(Cl)c3)c4ccccc4)C(=O)OC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P02 compound treatment 578965.0 6540.0 0.03 541414.0 -4480.0 -0.02 0.005 0.1368 1569526 ChemDiv1_010188 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)C(=O)OCC(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P03 compound treatment 578760.0 6340.0 0.03 538305.0 -7590.0 -0.04 -0.0065 -0.1384 1557380 ChemDiv1_010189 CCCC(=O)N1C(C)CC(Nc2ccccc2C)c3cccc(C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P04 compound treatment 586650.0 14200.0 0.06 544620.0 -1270.0 -0.01 0.0406 0.6341 1786202 ChemDiv1_010190 COc1ccccc1NC(=O)Cn2cnc(n2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P05 compound treatment 569589.0 -2830.0 -0.01 548849.0 2960.0 0.01 0.0014 0.0717 1243634 ChemDiv1_010191 O=C(CSc1nc2ccccc2o1)N3CCc4ccccc4C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P06 compound treatment 593594.0 21200.0 0.09 556394.0 10500.0 0.05 0.1038 0.9601 1974867 ChemDiv1_010192 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P07 compound treatment 581614.0 9190.0 0.04 548493.0 2600.0 0.01 0.0382 0.8862 1406825 ChemDiv1_010193 CCC(=O)Nc1ccc(Nc2nc(Cl)nc(Nc3ccc(NC(=O)CC)cc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P08 compound treatment 1395204.0 823000.0 3.68 1215217.0 669000.0 3.32 4.9489 0.9986 1534172 ChemDiv1_010194 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(cc3)N(C)C)c(=O)n2C1c4ccc(OC)cc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P09 compound treatment 603147.0 30700.0 0.14 568006.0 22100.0 0.11 0.1747 0.9937 1974868 ChemDiv1_010195 COC(=O)CSc1nc(cc(c1C#N)c2ccc(OC)cc2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P10 compound treatment 596431.0 24000.0 0.11 543319.0 -2570.0 -0.01 0.067 0.619 1574047 ChemDiv1_010196 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(OC)cc3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P11 compound treatment 616744.0 44300.0 0.2 549646.0 3760.0 0.02 0.1534 0.77 1974869 ChemDiv1_010197 COC(=O)c1ccc(cc1)C2C(=C(N)Oc3c2c(C)nn3c4cccc(Cl)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P12 compound treatment 555516.0 -16900.0 -0.08 526997.0 -18900.0 -0.09 -0.1197 -0.9945 1974870 ChemDiv1_010198 OC(=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)c(c4)[N+](=O)[O-])sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P13 compound treatment 588802.0 16400.0 0.07 557079.0 11200.0 0.06 0.091 0.9905 1709606 ChemDiv1_010199 CN1C2CCC1C=C(C2)N(CCc3c[nH]c4ccccc34)C(=O)c5cc(Cl)cc(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P14 compound treatment 602837.0 30400.0 0.14 568774.0 22900.0 0.11 0.1764 0.9959 1974871 ChemDiv1_010200 COc1ccccc1N(CCOC(=O)c2ccccc2)S(=O)(=O)c3ccc(NC4=NS(=O)(=O)c5ccccc45)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P15 compound treatment 600727.0 28300.0 0.13 562742.0 16900.0 0.08 0.1486 0.9795 1780116 ChemDiv1_010201 [O-][N+](=O)c1cccc(c1)C(=O)COC(=O)c2cccc(c2)N3C(=O)C4C5CC(C=C5)C4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P16 compound treatment 873764.0 301000.0 1.35 746492.0 201000.0 0.99 1.6565 0.9887 1974872 ChemDiv1_010202 CCc1ccc(cc1)N2C(=O)/C(=C/c3cc(Cl)c(O)c(OC)c3)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P17 compound treatment 612527.0 40100.0 0.18 577292.0 31400.0 0.16 0.2369 0.9975 1974873 ChemDiv1_010203 Cc1ccc(cc1C)C(=O)COC(=O)C(CCCCN2C(=O)C3C4CC(C=C4)C3C2=O)N5C(=O)C6C7CC(C=C7)C6C5=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P18 compound treatment 1334084.0 762000.0 3.41 1019355.0 473000.0 2.35 4.0694 0.9833 1974874 ChemDiv1_010204 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)cc([N+](=O)[O-])c3O)c(=O)n2C1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P19 compound treatment 612007.0 39600.0 0.18 577046.0 31200.0 0.15 0.2344 0.9976 1974875 ChemDiv1_010205 CC1CCC2C(C1)C(=O)N(CN(C(=O)C)c3ccc(C)c(Cl)c3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P20 compound treatment 602317.0 29900.0 0.13 584146.0 38300.0 0.19 0.2286 0.9855 1882633 ChemDiv1_010206 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccc([N+](=O)[O-])c3O)c(=O)n2C1c4cccc(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P21 compound treatment 559382.0 -13000.0 -0.06 563623.0 17700.0 0.09 0.0208 0.1975 1974876 ChemDiv1_010207 [O-][N+](=O)c1cc(ccc1Cl)C(=O)COC(=O)c2ccc(cc2)N3C(=O)C4CC=CCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P22 compound treatment 587854.0 15400.0 0.07 577029.0 31100.0 0.15 0.1579 0.9343 1974877 ChemDiv1_010208 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc(ccc4N5CCN(C)CC5)[N+](=O)[O-])c(=O)n23)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P23 mock treatment 551077.0 -21300.0 -0.1 550251.0 4360.0 0.02 -0.0523 -0.5338 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.615 P24 mock treatment 440603.0 -132000.0 -0.59 447083.0 -98800.0 -0.49 -0.7634 -0.9957 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A01 compound treatment 600208.0 11200.0 0.05 618909.0 23200.0 0.12 0.1168 0.9306 1974878 ChemDiv1_010209 CCOC(=O)C1=C(C)N=c2sc(=Cc3cccn3c4ccc(cc4)[N+](=O)[O-])c(=O)n2C1c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A02 compound treatment 605633.0 16600.0 0.07 604196.0 8530.0 0.04 0.0825 0.964 1974879 ChemDiv1_010210 CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(F)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A03 compound treatment 624158.0 35100.0 0.16 614419.0 18700.0 0.09 0.1769 0.9684 1586414 ChemDiv1_010211 Clc1ccc(cc1)c2nc(NCC3CCCO3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A04 compound treatment 624489.0 35500.0 0.16 621600.0 25900.0 0.13 0.2031 0.9945 1974880 ChemDiv1_010212 CCN/1C(=O)CC(S\C1=N/c2ccc(cc2)C(=O)OC)C(=O)Nc3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A05 compound treatment 644664.0 55600.0 0.25 622374.0 26700.0 0.13 0.2697 0.9562 1974881 ChemDiv1_010213 [O-][N+](=O)c1ccc(OCC(=O)Nc2nnc[nH]2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A06 compound treatment 663319.0 74300.0 0.33 640491.0 44800.0 0.22 0.3922 0.9807 1974882 ChemDiv1_010214 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3cccc(Cl)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A07 compound treatment 675141.0 86100.0 0.39 640355.0 44700.0 0.22 0.4291 0.9653 1974883 ChemDiv1_010215 COc1ccc(Oc2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A08 compound treatment 702836.0 114000.0 0.51 638093.0 42400.0 0.21 0.5089 0.9233 1974884 ChemDiv1_010216 CN(C1=NC(=O)C(S1)C2SC(=O)NC2=O)c3ccc(O)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A09 compound treatment 690823.0 102000.0 0.46 658061.0 62400.0 0.31 0.5408 0.9821 1196330 ChemDiv1_010217 COc1ccc(Oc2coc3cc(OC(=O)c4cncc(Br)c4)ccc3c2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A10 compound treatment 709227.0 120000.0 0.54 665138.0 69500.0 0.34 0.6238 0.9767 1238281 ChemDiv1_010218 CCOc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4ccncc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A11 compound treatment 724647.0 136000.0 0.61 640071.0 44400.0 0.22 0.5848 0.9057 1974885 ChemDiv1_010219 CCC1CCCCN1C(=O)CCN2C(=O)/C(=C/c3cc(OC)c(OC)c(OC)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A12 compound treatment 686976.0 98000.0 0.44 638009.0 42300.0 0.21 0.4584 0.943 1326128 ChemDiv1_010220 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A13 compound treatment 706820.0 118000.0 0.53 661413.0 65700.0 0.33 0.6032 0.9732 1974886 ChemDiv1_010221 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCN(CC3)c4ccccc4)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A14 compound treatment 707987.0 119000.0 0.53 667486.0 71800.0 0.36 0.6281 0.9808 1974887 ChemDiv1_010222 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A15 compound treatment 689559.0 101000.0 0.45 660806.0 65100.0 0.32 0.5464 0.9867 1974888 ChemDiv1_010223 Cc1cccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A16 compound treatment 709513.0 120000.0 0.54 649831.0 54200.0 0.27 0.5711 0.948 1974889 ChemDiv1_010224 Brc1ccc(OCCSc2nc3ccccc3[nH]2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A17 compound treatment 710397.0 121000.0 0.54 672332.0 76700.0 0.38 0.6527 0.9847 1974890 ChemDiv1_010225 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cccc(c3)C(F)(F)F)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A18 compound treatment 700056.0 111000.0 0.5 662035.0 66400.0 0.33 0.5839 0.9799 1974891 ChemDiv1_010226 CC(C)OC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A19 compound treatment 671187.0 82200.0 0.37 643108.0 47400.0 0.24 0.4263 0.9766 1785253 ChemDiv1_010227 [O-][N+](=O)c1ccc2[nH]c3C(=O)NCCc3c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A20 compound treatment 649328.0 60300.0 0.27 640972.0 45300.0 0.22 0.3496 0.9958 1974892 ChemDiv1_010228 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(cc3)N4CCOCC4)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A21 compound treatment 637681.0 48700.0 0.22 634623.0 39000.0 0.19 0.2905 0.9982 1974893 ChemDiv1_010229 CN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A22 compound treatment 626049.0 37000.0 0.17 622217.0 26500.0 0.13 0.2102 0.9934 1158633 ChemDiv1_010230 CCOC(=O)c1c(CSc2cccs2)n(C)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A23 mock treatment 608943.0 19900.0 0.09 606395.0 10700.0 0.05 0.1006 0.9693 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 A24 mock treatment 534177.0 -54800.0 -0.25 507489.0 -88200.0 -0.44 -0.4825 -0.9628 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B01 compound treatment 603939.0 14900.0 0.07 594157.0 -1510.0 -0.01 0.0419 0.6239 1187156 ChemDiv1_010231 O=C(Nc1ccc2oc(nc2c1)c3ccncc3)c4cccc(OCc5ccccc5)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B02 compound treatment 638448.0 49400.0 0.22 646210.0 50500.0 0.25 0.3335 0.9981 1294338 ChemDiv1_010232 CCOC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(OC(=O)C)cc4OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B03 compound treatment 680590.0 91600.0 0.41 711917.0 116000.0 0.58 0.6971 0.9861 1974894 ChemDiv1_010233 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3cc(ccc3Cl)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B04 compound treatment 642590.0 53600.0 0.24 666803.0 71100.0 0.35 0.4188 0.9824 1935793 ChemDiv1_010234 Oc1cc(Cl)c([N+](=O)[O-])c2C3C=CCC3C(Nc12)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B05 compound treatment 699670.0 111000.0 0.5 709685.0 114000.0 0.56 0.7496 0.9979 1654902 ChemDiv1_010235 COc1cc(cc(OC)c1O)C2NC(=O)NC(=C2C(=O)OCc3ccc(C)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B06 compound treatment 1187166.0 598000.0 2.68 1193008.0 597000.0 2.96 3.9857 0.9988 1974895 ChemDiv1_010236 CC(N1C(=O)/C(=C\c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B07 compound treatment 740954.0 152000.0 0.68 718496.0 123000.0 0.61 0.9112 0.9985 1974896 ChemDiv1_010237 COC(=O)C1=CN(C=C(C1c2cc(OC)c(OC)c(OC)c2)C(=O)OC)c3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B08 compound treatment 991125.0 402000.0 1.8 1004278.0 409000.0 2.02 2.7041 0.9983 1974897 ChemDiv1_010238 CC1CN(CC(C)O1)c2nc3c(C)cccn3c(=O)c2/C=C\4/SC(=S)N(C5CCCCC5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B09 compound treatment 726869.0 138000.0 0.62 758893.0 163000.0 0.81 1.0081 0.9911 1158624 ChemDiv1_010239 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B10 compound treatment 731609.0 143000.0 0.64 742436.0 147000.0 0.73 0.9655 0.9979 1212617 ChemDiv1_010240 OC1(CC(=O)c2ccco2)C(=O)Nc3ccc(Br)cc31 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B11 compound treatment 749728.0 161000.0 0.72 744119.0 148000.0 0.74 1.0287 0.9999 1974898 ChemDiv1_010241 CN(C)c1nc(OCCOC(=O)Nc2sc(=S)n(C)c2C)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B12 compound treatment 692181.0 103000.0 0.46 713903.0 118000.0 0.59 0.7407 0.9931 1231597 ChemDiv1_010242 CN(C)c1ccc(cc1)C(=O)CC2(O)C(=O)Nc3ccc(C)cc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B13 compound treatment 754141.0 165000.0 0.74 747712.0 152000.0 0.75 1.0553 1.0 1974899 ChemDiv1_010243 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B14 compound treatment 722212.0 133000.0 0.6 724953.0 129000.0 0.64 0.8745 0.9994 1974900 ChemDiv1_010244 O=C(Nc1ccccc1Sc2ncnc3sc4CCCCc4c23)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B15 compound treatment 773779.0 185000.0 0.83 776514.0 181000.0 0.9 1.2183 0.9992 1974901 ChemDiv1_010245 Cc1cc(OCc2nc(no2)c3ccc(Br)cc3)ccc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B16 compound treatment 735155.0 146000.0 0.65 730955.0 135000.0 0.67 0.9365 0.9999 1974902 ChemDiv1_010246 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3cccc(Br)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B17 compound treatment 753494.0 164000.0 0.74 752148.0 156000.0 0.78 1.0687 0.9997 1974903 ChemDiv1_010247 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OCC#C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B18 compound treatment 751557.0 163000.0 0.73 714515.0 119000.0 0.59 0.9308 0.9945 1974904 ChemDiv1_010248 Cc1ccc(cc1)S(=O)(=O)N2CCN(CCNC(=O)C(=O)NCc3ccccc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B19 compound treatment 760621.0 172000.0 0.77 720046.0 124000.0 0.62 0.9789 0.994 1974905 ChemDiv1_010249 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3cc(C)c(Cl)c(C)c3)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B20 compound treatment 722678.0 134000.0 0.6 699690.0 104000.0 0.52 0.7875 0.9972 1974906 ChemDiv1_010250 CC(C)c1ccc(C#N)c(SCC(=O)Nc2ccccc2C(=O)O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B21 compound treatment 736980.0 148000.0 0.66 712552.0 117000.0 0.58 0.8778 0.9978 1974907 ChemDiv1_010251 CC/N=C/1\SC(CC(=O)Nc2sc(C)c(C)c2C(=O)OC)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B22 compound treatment 689652.0 101000.0 0.45 678155.0 82500.0 0.41 0.6075 0.9988 1612904 ChemDiv1_010252 CC(C)c1ccc(C#N)c(SCC(=O)Nc2cccc(c2)C(=O)O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B23 mock treatment 668156.0 79100.0 0.35 652997.0 57300.0 0.28 0.4513 0.994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 B24 mock treatment 536518.0 -52500.0 -0.23 576371.0 -19300.0 -0.1 -0.2338 -0.9214 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C01 compound treatment 625395.0 36400.0 0.16 646274.0 50600.0 0.25 0.2924 0.9782 1941722 ChemDiv1_010253 COc1cc(/C=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)ccc1OCc4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C02 compound treatment 662462.0 73400.0 0.33 662208.0 66500.0 0.33 0.4656 1.0 1974908 ChemDiv1_010254 CCOc1cccc(NC(=O)C2CC(=O)N(C)/C(=N/c3cc(Cl)cc(Cl)c3)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C03 compound treatment 711716.0 123000.0 0.55 710182.0 115000.0 0.57 0.7895 0.9999 1974909 ChemDiv1_010255 COCCN(CCOC)c1nc(nc2ccccc12)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C04 compound treatment 693679.0 105000.0 0.47 725978.0 130000.0 0.65 0.7877 0.9876 1974910 ChemDiv1_010256 CN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C05 compound treatment 753636.0 165000.0 0.74 776719.0 181000.0 0.9 1.1553 0.9952 1974911 ChemDiv1_010257 COc1cc(C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)c(Br)c(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C06 compound treatment 729827.0 141000.0 0.63 708929.0 113000.0 0.56 0.8424 0.9983 1974912 ChemDiv1_010258 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(C)c(C)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C07 compound treatment 745241.0 156000.0 0.7 769160.0 173000.0 0.86 1.1022 0.9948 1950251 ChemDiv1_010259 CCOC(=O)Oc1ccc2c(=O)c(Oc3ccc(OC)cc3)c(oc2c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C08 compound treatment 757207.0 168000.0 0.75 769730.0 174000.0 0.86 1.1421 0.9977 1974913 ChemDiv1_010260 CCOc1ccc(/N=C/2\NC(=O)S\C2=C/3\C(=O)Nc4ccc(Br)cc34)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C09 compound treatment 800307.0 211000.0 0.95 792368.0 197000.0 0.97 1.3578 0.9999 1974914 ChemDiv1_010261 Brc1ccccc1NC(=O)CCCN2C(=O)/C(=C\c3cccs3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C10 compound treatment 766234.0 177000.0 0.79 759621.0 164000.0 0.81 1.1353 0.9999 1924229 ChemDiv1_010262 Cc1ccc(OCc2nc(no2)c3ccc(Cl)cc3)c(Br)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C11 compound treatment 813856.0 225000.0 1.01 803439.0 208000.0 1.03 1.4395 0.9999 1974915 ChemDiv1_010263 COc1cc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccccc3O)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C12 compound treatment 741374.0 152000.0 0.68 720863.0 125000.0 0.62 0.9208 0.9989 1274587 ChemDiv1_010264 COc1ccccc1N2CCN(Cc3cc(COCc4ccccc4)c5cccnc5c3O)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C13 compound treatment 798584.0 210000.0 0.94 741102.0 145000.0 0.72 1.1728 0.9915 1974916 ChemDiv1_010265 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc(OC)c(OC)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C14 compound treatment 764564.0 176000.0 0.79 767948.0 172000.0 0.85 1.1591 0.9992 1722632 ChemDiv1_010266 Clc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C15 compound treatment 842283.0 253000.0 1.13 1570225.0 975000.0 4.83 4.2154 0.85 1389931 ChemDiv1_010267 CCC(Sc1nc2ccccc2o1)C(=O)Nc3cc(C)on3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C16 compound treatment 800712.0 212000.0 0.95 777934.0 182000.0 0.9 1.3085 0.9997 1302732 ChemDiv1_010268 O=C(Nc1nc2ccccc2n1CCOc3ccccc3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C17 compound treatment 801697.0 213000.0 0.95 774183.0 179000.0 0.88 1.2985 0.9993 1974917 ChemDiv1_010269 CCN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C18 compound treatment 919891.0 331000.0 1.48 912325.0 317000.0 1.57 2.1565 0.9996 1974918 ChemDiv1_010270 COC(=O)c1cc(ccc1Cl)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C19 compound treatment 754236.0 165000.0 0.74 761192.0 166000.0 0.82 1.1028 0.9987 1974919 ChemDiv1_010271 COc1ccc2[nH]cc(CCN3C(=O)C4CCCCC4C3=O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C20 compound treatment 750410.0 161000.0 0.72 732393.0 137000.0 0.68 0.9898 0.9995 1974920 ChemDiv1_010272 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(O)c(OC)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C21 compound treatment 764375.0 175000.0 0.78 740862.0 145000.0 0.72 1.0637 0.999 1974921 ChemDiv1_010273 CCN/1C(=O)CC(S\C1=N/c2ccc(OC)cc2)C(=O)Nc3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C22 compound treatment 715490.0 126000.0 0.57 720023.0 124000.0 0.62 0.8359 0.9991 1387424 ChemDiv1_010274 CCOC(=O)c1c(CSc2ccccc2)oc3cc(CN(C)C)c(O)c(Cl)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C23 mock treatment 706551.0 118000.0 0.53 686273.0 90600.0 0.45 0.6894 0.9969 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 C24 mock treatment 534889.0 -54100.0 -0.24 551229.0 -44400.0 -0.22 -0.327 -0.9989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D01 compound treatment 598054.0 9040.0 0.04 587908.0 -7760.0 -0.04 0.0014 0.0255 1284668 ChemDiv1_010275 COc1ccc(cc1OC)c2cn3ccc4ccccc4c3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D02 compound treatment 640751.0 51700.0 0.23 634105.0 38400.0 0.19 0.2984 0.9953 1974922 ChemDiv1_010276 CC(=O)Oc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D03 compound treatment 698986.0 110000.0 0.49 713416.0 118000.0 0.58 0.7605 0.9964 1974923 ChemDiv1_010277 FC(F)(F)c1ccc(Cl)c(c1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D04 compound treatment 950552.0 362000.0 1.62 903152.0 307000.0 1.52 2.2214 0.9995 1456653 ChemDiv1_010278 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D05 compound treatment 716377.0 127000.0 0.57 737391.0 142000.0 0.7 0.8996 0.9947 1532111 ChemDiv1_010279 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)c(Br)c3)C(=O)CC(C2)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D06 compound treatment 1838081.0 1250000.0 5.59 1946396.0 1350000.0 6.69 8.6851 0.996 1974924 ChemDiv1_010280 OCCN1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(CC5CCCO5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D07 compound treatment 736884.0 148000.0 0.66 753781.0 158000.0 0.78 1.0219 0.9965 1312882 ChemDiv1_010281 CC(=O)Oc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D08 compound treatment 1398031.0 809000.0 3.62 1295185.0 700000.0 3.47 5.0111 0.9998 1974925 ChemDiv1_010282 CN(Cc1ccccc1)c2nc3c(C)cccn3c(=O)c2/C=C\4/SC(=S)N(Cc5ccco5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D09 compound treatment 740299.0 151000.0 0.68 774643.0 179000.0 0.89 1.1058 0.9912 1560238 ChemDiv1_010283 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(CC)c3n2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D10 compound treatment 749927.0 161000.0 0.72 789320.0 194000.0 0.96 1.1877 0.99 1201587 ChemDiv1_010284 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccccc4Cl)c5ccccc51 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D11 compound treatment 769516.0 181000.0 0.81 803352.0 208000.0 1.03 1.2988 0.9929 1974926 ChemDiv1_010285 CN(C)c1nc(SCCOC(=O)Nc2sc(=S)n(C)c2C)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D12 compound treatment 744705.0 156000.0 0.7 712852.0 117000.0 0.58 0.9033 0.9959 1266765 ChemDiv1_010286 COc1ccc(cc1OC)C2Oc3ccc(Cl)cc3C4CC(=NN42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D13 compound treatment 764412.0 175000.0 0.79 758219.0 163000.0 0.81 1.1246 0.9999 1974927 ChemDiv1_010287 Cc1c(NC(=O)CN(c2cccc(C)c2C)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D14 compound treatment 1255559.0 667000.0 2.98 1307171.0 712000.0 3.52 4.6021 0.9966 1974928 ChemDiv1_010288 Cc1ccc2nc(N3CCCCC3)c(/C=C/4\SC(=S)N(CC5CCCO5)C4=O)c(=O)n2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D15 compound treatment 795588.0 207000.0 0.92 809968.0 214000.0 1.06 1.4045 0.9976 1974929 ChemDiv1_010289 COc1ccc(cc1)C2CC(=O)NC(=N2)Nc3nc(C)c4ccc(C)cc4n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D16 compound treatment 744699.0 156000.0 0.7 739176.0 144000.0 0.71 0.9955 1.0 1974930 ChemDiv1_010290 Cc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3cccc(C)c3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D17 compound treatment 795647.0 207000.0 0.92 749874.0 154000.0 0.76 1.1942 0.9955 1974931 ChemDiv1_010291 CCOc1cc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OCC#C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D18 compound treatment 746884.0 158000.0 0.71 724626.0 129000.0 0.64 0.9514 0.9987 1974932 ChemDiv1_010292 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccc(C)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D19 compound treatment 785689.0 197000.0 0.88 736779.0 141000.0 0.7 1.1168 0.9935 1974933 ChemDiv1_010293 COC(=O)c1c(NC(=O)CC2S/C(=N\C)/N(C)C2=O)sc3CCCCc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D20 compound treatment 749285.0 160000.0 0.72 712505.0 117000.0 0.58 0.9166 0.9943 1974934 ChemDiv1_010294 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)c(F)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D21 compound treatment 750825.0 162000.0 0.72 726952.0 131000.0 0.65 0.972 0.9986 1974935 ChemDiv1_010295 CC/N=C/1\SC(CC(=O)Nc2sc3CCCCc3c2C(=O)OC)C(=O)N1CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D22 compound treatment 726071.0 137000.0 0.61 719395.0 124000.0 0.61 0.8672 1.0 1697941 ChemDiv1_010296 CC(C)Cc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D23 mock treatment 710035.0 121000.0 0.54 692285.0 96600.0 0.48 0.7215 0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 D24 mock treatment 543659.0 -45400.0 -0.2 540695.0 -55000.0 -0.27 -0.3361 -0.9895 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E01 compound treatment 620377.0 31400.0 0.14 626427.0 30800.0 0.15 0.207 0.9992 1246750 ChemDiv1_010297 CCOC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E02 compound treatment 673468.0 84500.0 0.38 666278.0 70600.0 0.35 0.5147 0.9992 1974936 ChemDiv1_010298 CCOC(=O)c1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccccc3F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E03 compound treatment 731454.0 142000.0 0.64 761828.0 166000.0 0.82 1.0329 0.992 1137633 ChemDiv1_010299 CCN1CCN(CC1)c2nc(nc3ccccc23)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E04 compound treatment 718506.0 129000.0 0.58 731931.0 136000.0 0.68 0.8872 0.9971 1974937 ChemDiv1_010300 CCN/1C(=O)CC(S\C1=N/c2ccc3OCOc3c2)C(=O)Nc4ccc(cc4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E05 compound treatment 945883.0 357000.0 1.6 756999.0 161000.0 0.8 1.6947 0.9488 1974938 ChemDiv1_010301 CC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E06 compound treatment 748872.0 160000.0 0.72 751468.0 156000.0 0.77 1.0517 0.9993 1974939 ChemDiv1_010302 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(OCC)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E07 compound treatment 812951.0 224000.0 1.0 832199.0 237000.0 1.17 1.5374 0.997 1718575 ChemDiv1_010303 CC(C)(C)c1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E08 compound treatment 747573.0 159000.0 0.71 766033.0 170000.0 0.84 1.0986 0.9963 1974940 ChemDiv1_010304 COc1ccc(/N=C/2\NC(=O)S\C2=C/3\C(=O)Nc4ccc(Br)cc34)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E09 compound treatment 795418.0 206000.0 0.92 805586.0 210000.0 1.04 1.3886 0.9983 1974941 ChemDiv1_010305 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCO)c3ccccc3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E10 compound treatment 746249.0 157000.0 0.7 757159.0 161000.0 0.8 1.0634 0.998 1153499 ChemDiv1_010306 COc1ccc(cc1OC)c2noc(COc3ccc(C)cc3Br)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E11 compound treatment 800474.0 211000.0 0.95 830180.0 235000.0 1.16 1.4908 0.9948 1974942 ChemDiv1_010307 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)N3CCN(CC3)c4ccccc4)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E12 compound treatment 845368.0 256000.0 1.15 804504.0 209000.0 1.03 1.543 0.9987 1436905 ChemDiv1_010308 COc1c(Cl)cc(Cl)cc1c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E13 compound treatment 822326.0 233000.0 1.04 807522.0 212000.0 1.05 1.4806 1.0 1974943 ChemDiv1_010309 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cc(Cl)ccc3O)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E14 compound treatment 754141.0 165000.0 0.74 771428.0 176000.0 0.87 1.1383 0.9967 1266962 ChemDiv1_010310 Clc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E15 compound treatment 793508.0 204000.0 0.92 828860.0 233000.0 1.16 1.4641 0.9934 1396098 ChemDiv1_010311 CCC(Sc1nncn1C)C(=O)Nc2cc(C)on2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E16 compound treatment 823048.0 234000.0 1.05 797021.0 201000.0 1.0 1.4461 0.9997 1974944 ChemDiv1_010312 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc(cc4)C(=O)O)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E17 compound treatment 817331.0 228000.0 1.02 803238.0 208000.0 1.03 1.4498 1.0 1974945 ChemDiv1_010313 CCN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccccc3OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E18 compound treatment 853240.0 264000.0 1.18 820256.0 225000.0 1.11 1.623 0.9995 1974946 ChemDiv1_010314 CCOC(=O)c1cc(ccc1Cl)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E19 compound treatment 793488.0 204000.0 0.92 709377.0 114000.0 0.56 1.0455 0.9728 1974947 ChemDiv1_010315 O=C1C2CCCCC2C(=O)N1c3ccc(cc3)S(=O)(=O)Nc4ncccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E20 compound treatment 786534.0 198000.0 0.88 746891.0 151000.0 0.75 1.1549 0.9966 1974948 ChemDiv1_010316 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3cc(Cl)c(O)c(OC)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E21 compound treatment 764430.0 175000.0 0.79 758689.0 163000.0 0.81 1.1263 0.9999 1974949 ChemDiv1_010317 CCN/1C(=O)CC(S\C1=N/c2ccc(OC)cc2)C(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E22 compound treatment 710082.0 121000.0 0.54 692842.0 97200.0 0.48 0.7236 0.9983 1170940 ChemDiv1_010318 CCOC(=O)c1c(CN(C)CCO)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E23 mock treatment 707562.0 119000.0 0.53 714224.0 119000.0 0.59 0.7905 0.9987 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 E24 mock treatment 535884.0 -53100.0 -0.24 530538.0 -65100.0 -0.32 -0.3963 -0.9887 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F01 compound treatment 631131.0 42100.0 0.19 622976.0 27300.0 0.14 0.229 0.9867 1974950 ChemDiv1_010319 CCOC(=O)N1CCN(CC1)C(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F02 compound treatment 647928.0 58900.0 0.26 642423.0 46800.0 0.23 0.3502 0.9979 1974951 ChemDiv1_010320 COc1cc([N+](=O)[O-])c2NC(C3CC=CC3c2c1)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F03 compound treatment 690784.0 102000.0 0.46 737036.0 141000.0 0.7 0.8173 0.9783 1974952 ChemDiv1_010321 COc1ccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F04 compound treatment 702666.0 114000.0 0.51 721019.0 125000.0 0.62 0.7988 0.9951 1974953 ChemDiv1_010322 OC(=O)C1CCC(CC1)N2C(=O)C3CCCCC3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F05 compound treatment 694253.0 105000.0 0.47 769730.0 174000.0 0.86 0.9428 0.9596 1513788 ChemDiv1_010323 CC(=O)Oc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F06 compound treatment 2485986.0 1900000.0 8.49 2663891.0 2070000.0 10.25 13.2491 0.9956 1974954 ChemDiv1_010324 COCCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F07 compound treatment 745729.0 157000.0 0.7 767416.0 172000.0 0.85 1.0977 0.9954 1974955 ChemDiv1_010325 CCOC(=O)c1ccc(cc1)N2C=C(C(C(=C2)C(=O)OC)c3cc(Br)c(O)c(OC)c3)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F08 compound treatment 1304872.0 716000.0 3.2 1232023.0 636000.0 3.15 4.495 1.0 1974956 ChemDiv1_010326 O=C/1N(C2CCCCC2)C(=S)S\C1=C/c3c(NCc4ccco4)nc5ccccn5c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F09 compound treatment 759376.0 170000.0 0.76 751491.0 156000.0 0.77 1.0851 1.0 1138859 ChemDiv1_010327 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(CC=C)c3n2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F10 compound treatment 754435.0 165000.0 0.74 759987.0 164000.0 0.81 1.0992 0.9989 1516706 ChemDiv1_010328 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccccc3Cl)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F11 compound treatment 761564.0 173000.0 0.77 771805.0 176000.0 0.87 1.1631 0.9982 1974957 ChemDiv1_010329 CN(C)c1nc(OCCOC(=O)Nc2sc(NS(=O)(=O)c3ccc(C)cc3)nc2C)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F12 compound treatment 713738.0 125000.0 0.56 743478.0 148000.0 0.73 0.9125 0.991 1974958 ChemDiv1_010330 COc1ccc(cc1)C2Oc3ccc(Br)cc3C4CC(=NN42)c5ccc(C)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F13 compound treatment 768008.0 179000.0 0.8 749990.0 154000.0 0.76 1.1071 0.9997 1974959 ChemDiv1_010331 CN(Cc1ccccc1)C(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F14 compound treatment 740004.0 151000.0 0.68 724702.0 129000.0 0.64 0.9299 0.9996 1974960 ChemDiv1_010332 [O-][N+](=O)c1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F15 compound treatment 791600.0 203000.0 0.91 780951.0 185000.0 0.92 1.2903 1.0 1974961 ChemDiv1_010333 CCOc1ccc2nc(NC3=NC(CC(=O)N3)c4ccc(OC)cc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F16 compound treatment 730182.0 141000.0 0.63 735548.0 140000.0 0.69 0.9368 0.9989 1974962 ChemDiv1_010334 O=C(NCCN1CCN(CC1)S(=O)(=O)c2ccccc2)C(=O)Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F17 compound treatment 778770.0 190000.0 0.85 733556.0 138000.0 0.68 1.0836 0.9942 1974963 ChemDiv1_010335 COc1cc(/C=C/2\C(=NN(C2=O)c3cccc(Br)c3)C)ccc1OC(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F18 compound treatment 742076.0 153000.0 0.69 716431.0 121000.0 0.6 0.9075 0.9977 1974964 ChemDiv1_010336 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(OC)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F19 compound treatment 768889.0 180000.0 0.81 747335.0 152000.0 0.75 1.1006 0.9994 1974965 ChemDiv1_010337 C/N=C/1\SC(CC(=O)N)C(=O)N1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F20 compound treatment 706727.0 118000.0 0.53 688924.0 93300.0 0.46 0.6993 0.9978 1293977 ChemDiv1_010338 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cc(F)ccc2F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F21 compound treatment 697097.0 108000.0 0.48 723859.0 128000.0 0.64 0.7911 0.991 1974966 ChemDiv1_010339 O=C1CSC(N1Cc2ccco2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F22 compound treatment 707780.0 119000.0 0.53 710177.0 115000.0 0.57 0.777 0.9995 1974967 ChemDiv1_010340 CC(C)c1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F23 mock treatment 676614.0 87600.0 0.39 682849.0 87200.0 0.43 0.5827 0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 F24 mock treatment 512905.0 -76100.0 -0.34 515720.0 -79900.0 -0.4 -0.521 -0.9972 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G01 compound treatment 632431.0 43400.0 0.19 623411.0 27700.0 0.14 0.2346 0.9856 1929269 ChemDiv1_010341 Clc1ccc(OCCCC(=O)Nc2nnc[nH]2)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G02 compound treatment 646681.0 57700.0 0.26 676889.0 81200.0 0.4 0.467 0.977 1974968 ChemDiv1_010342 CN/1C(=O)CC(S\C1=N/c2ccc(Br)cc2)C(=O)Nc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G03 compound treatment 704899.0 116000.0 0.52 749903.0 154000.0 0.76 0.9071 0.9822 1724662 ChemDiv1_010343 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G04 compound treatment 698768.0 110000.0 0.49 742356.0 147000.0 0.73 0.8612 0.9818 1974969 ChemDiv1_010344 COc1cccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(Br)cc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G05 compound treatment 1197733.0 609000.0 2.72 1264859.0 669000.0 3.32 4.2708 0.9953 1443677 ChemDiv1_010345 COC(=O)c1cccc(Nc2nc(nc3ccccc23)c4ccccc4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G06 compound treatment 708617.0 120000.0 0.54 738271.0 143000.0 0.71 0.8781 0.9906 1974970 ChemDiv1_010346 CCCOc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(OC)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G07 compound treatment 777045.0 188000.0 0.84 817192.0 222000.0 1.1 1.3711 0.9914 1444843 ChemDiv1_010347 CC(C)(C)c1ccc(cc1)c2nc(NCc3cccnc3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G08 compound treatment 738295.0 149000.0 0.67 739817.0 144000.0 0.71 0.9774 0.9995 1406003 ChemDiv1_010348 COc1ccc(cc1)C(=O)COC(=O)c2ccc3OCCOc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G09 compound treatment 773110.0 184000.0 0.82 786951.0 191000.0 0.95 1.2527 0.9976 1974971 ChemDiv1_010349 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N3CCCc4ccccc34)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G10 compound treatment 735974.0 147000.0 0.66 756347.0 161000.0 0.8 1.028 0.9955 1974972 ChemDiv1_010350 COc1ccc(cc1)c2noc(CCCOc3ccc(Cl)cc3Cl)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G11 compound treatment 789961.0 201000.0 0.9 793442.0 198000.0 0.98 1.3288 0.9991 1974973 ChemDiv1_010351 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)Nc3nnc(CC(C)C)s3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G12 compound treatment 748321.0 159000.0 0.71 784035.0 188000.0 0.93 1.1641 0.9912 1610297 ChemDiv1_010352 Brc1ccc(OCCn2c(NC(=O)c3cccs3)nc4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G13 compound treatment 771286.0 182000.0 0.82 802604.0 207000.0 1.03 1.3018 0.9936 1974974 ChemDiv1_010353 Cc1cccc(Oc2c(oc3cc(OC(=O)c4ccco4)ccc3c2=O)C(F)(F)F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G14 compound treatment 787909.0 199000.0 0.89 800925.0 205000.0 1.02 1.3485 0.9978 1191812 ChemDiv1_010354 Fc1ccc(cc1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G15 compound treatment 807372.0 218000.0 0.98 791593.0 196000.0 0.97 1.3775 1.0 1974975 ChemDiv1_010355 Oc1ccc(Br)cc1c2nc(Cl)c3ccccc3n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G16 compound treatment 779783.0 191000.0 0.85 793358.0 198000.0 0.98 1.2963 0.9977 1974976 ChemDiv1_010356 COC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G17 compound treatment 810363.0 221000.0 0.99 774824.0 179000.0 0.89 1.3282 0.9985 1974977 ChemDiv1_010357 COC(=O)CSc1nnc(c2ccncc2)n1Cc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G18 compound treatment 815322.0 226000.0 1.01 828490.0 233000.0 1.15 1.5319 0.9979 1974978 ChemDiv1_010358 CCOC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G19 compound treatment 776326.0 187000.0 0.84 726798.0 131000.0 0.65 1.0522 0.992 1974979 ChemDiv1_010359 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Br)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G20 compound treatment 731117.0 142000.0 0.64 683317.0 87600.0 0.43 0.7568 0.9827 1974980 ChemDiv1_010360 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3cc(Br)c(O)c(OC)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G21 compound treatment 747480.0 158000.0 0.71 735009.0 139000.0 0.69 0.9897 0.9999 1974981 ChemDiv1_010361 CCN/1C(=O)CC(S\C1=N/c2ccc(F)cc2)C(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G22 compound treatment 675747.0 86700.0 0.39 714008.0 118000.0 0.59 0.6891 0.98 1425199 ChemDiv1_010362 CCOC(=O)c1c(CSc2cccs2)n(C)c3cc(Br)c(O)c(CN(C)C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G23 mock treatment 692355.0 103000.0 0.46 700157.0 104000.0 0.52 0.6931 0.9984 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 G24 mock treatment 527334.0 -61700.0 -0.28 541113.0 -54600.0 -0.27 -0.3863 -0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H01 compound treatment 576553.0 -12500.0 -0.06 596597.0 927.0 0.0 -0.0362 -0.6467 1974982 ChemDiv1_010363 Cc1ccc(CSCCNC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H02 compound treatment 648098.0 59100.0 0.26 633498.0 37800.0 0.19 0.3195 0.9858 1325231 ChemDiv1_010364 CC(=O)Oc1ccc(cc1)C2Nc3c(cc(Cl)cc3C4C=CCC42)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H03 compound treatment 684636.0 95600.0 0.43 725007.0 129000.0 0.64 0.7557 0.9808 1974983 ChemDiv1_010365 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H04 compound treatment 700066.0 111000.0 0.5 705059.0 109000.0 0.54 0.7347 0.9991 1368873 ChemDiv1_010366 O=C(Nc1ccc(Cc2ccncc2)cc1)C3CCC(CC3)N4C(=O)C5CC=CCC5C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H05 compound treatment 723208.0 134000.0 0.6 738227.0 143000.0 0.71 0.9241 0.9968 1297550 ChemDiv1_010367 CC(C)OC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3F)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H06 compound treatment 1327549.0 739000.0 3.31 1391137.0 795000.0 3.94 5.1241 0.9962 1974984 ChemDiv1_010368 OCCNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(C4CCS(=O)(=O)C4)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H07 compound treatment 739358.0 150000.0 0.67 736226.0 141000.0 0.7 0.9682 0.9999 1673185 ChemDiv1_010369 COc1ccccc1C2CC(=O)C3=C(C2)NC(=C(C3c4cc(OC)c(OC)c(OC)c4)C(=O)OC5CCCC5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H08 compound treatment 705988.0 117000.0 0.52 731327.0 136000.0 0.67 0.8454 0.9924 1974985 ChemDiv1_010370 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)/C=C/c3ccccc3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H09 compound treatment 737899.0 149000.0 0.67 667310.0 71600.0 0.35 0.7222 0.9565 1620713 ChemDiv1_010371 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nnc(C)c(=O)[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H10 compound treatment 730076.0 141000.0 0.63 753022.0 157000.0 0.78 0.9977 0.9945 1594583 ChemDiv1_010372 OC1(CC(=O)c2cccs2)C(=O)N(Cc3ccccc3Cl)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H11 compound treatment 761888.0 173000.0 0.77 786080.0 190000.0 0.94 1.2142 0.9952 1473648 ChemDiv1_010373 CN(C)c1nc(Oc2ccc(OCc3ccccc3)nn2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H12 compound treatment 818100.0 229000.0 1.03 743540.0 148000.0 0.73 1.2431 0.9864 1974986 ChemDiv1_010374 Cc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC3c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H13 compound treatment 771515.0 183000.0 0.82 745286.0 150000.0 0.74 1.1018 0.9988 1974987 ChemDiv1_010375 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCCc2ccc(OC)c(OC)c2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H14 compound treatment 817768.0 229000.0 1.02 838499.0 243000.0 1.2 1.5747 0.9968 1974988 ChemDiv1_010376 Clc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H15 compound treatment 802404.0 213000.0 0.96 785549.0 190000.0 0.94 1.3406 1.0 1311873 ChemDiv1_010377 CCOc1ccc2nc(SC3CC(=O)N(C3=O)c4ccc(OC)cc4)nc(C)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H16 compound treatment 767776.0 179000.0 0.8 727950.0 132000.0 0.66 1.0292 0.9951 1974989 ChemDiv1_010378 CCc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)S(=O)(=O)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H17 compound treatment 784099.0 195000.0 0.87 748605.0 153000.0 0.76 1.1532 0.9975 1974990 ChemDiv1_010379 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)C(=O)O)C)ccc1OC(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H18 compound treatment 752306.0 163000.0 0.73 716548.0 121000.0 0.6 0.9403 0.9951 1974991 ChemDiv1_010380 CCOc1ccc(NC(=O)C(=O)NCCN2CCN(CC2)C(=O)c3ccc(C)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H19 compound treatment 756921.0 168000.0 0.75 732921.0 137000.0 0.68 1.0122 0.9987 1974992 ChemDiv1_010381 CCCCNC(=O)CC1S/C(=N\C)/N(C)C1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H20 compound treatment 734042.0 145000.0 0.65 710260.0 115000.0 0.57 0.8604 0.9978 1974993 ChemDiv1_010382 O=C(N/C(=C\c1ccco1)/C(=O)N2CCN(C/C=C/c3ccccc3)CC2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H21 compound treatment 745131.0 156000.0 0.7 723826.0 128000.0 0.63 0.9431 0.9989 1874291 ChemDiv1_010383 O=C1CSC(N1CC2CCCO2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H22 compound treatment 748756.0 160000.0 0.72 725422.0 130000.0 0.64 0.9601 0.9986 1585715 ChemDiv1_010384 CCCc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H23 mock treatment 672876.0 83900.0 0.38 693903.0 98200.0 0.49 0.6095 0.9918 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 H24 mock treatment 526267.0 -62700.0 -0.28 503207.0 -92500.0 -0.46 -0.5225 -0.9724 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I01 compound treatment 615466.0 26500.0 0.12 608571.0 12900.0 0.06 0.1289 0.9581 3116459 ChemDiv1_010385 COc1ccc(Oc2coc3c(CN4CCCCCC4)c(O)ccc3c2=O)cc1.C1CCCNCC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I02 compound treatment 665001.0 76000.0 0.34 678927.0 83300.0 0.41 0.5322 0.9954 1974994 ChemDiv1_010386 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I03 compound treatment 722288.0 133000.0 0.6 715904.0 120000.0 0.6 0.843 1.0 1184886 ChemDiv1_010387 COc1ccc(cc1OC)C(=O)Oc2ccc3c(=O)c(Oc4cccc(C)c4)coc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I04 compound treatment 717512.0 128000.0 0.58 726360.0 131000.0 0.65 0.8645 0.9983 1974995 ChemDiv1_010388 CN/1C(=O)CC(S\C1=N/c2cccc(F)c2)C(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I05 compound treatment 739964.0 151000.0 0.68 751199.0 156000.0 0.77 1.0226 0.9979 1974996 ChemDiv1_010389 CN1CCN(Cc2c(O)ccc3c(=O)c(c4cccc(Cl)c4)c(oc23)C(F)(F)F)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I06 compound treatment 728890.0 140000.0 0.63 722644.0 127000.0 0.63 0.8875 1.0 1974997 ChemDiv1_010390 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc4OCOc4c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I07 compound treatment 734909.0 146000.0 0.65 760273.0 165000.0 0.82 1.0384 0.9939 1974998 ChemDiv1_010391 COCCNc1nc(nc2ccccc12)c3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I08 compound treatment 747874.0 159000.0 0.71 743465.0 148000.0 0.73 1.0205 0.9999 1330195 ChemDiv1_010392 CC(=O)Oc1ccc(C2Nc3c(cc(Cl)cc3C4C=CCC42)C(=O)c5ccccc5)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I09 compound treatment 839666.0 251000.0 1.12 838280.0 243000.0 1.2 1.6432 0.9994 1974999 ChemDiv1_010393 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCC#N)c3ccccc3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I10 compound treatment 714589.0 126000.0 0.56 763577.0 168000.0 0.83 0.9856 0.9818 1975000 ChemDiv1_010394 [O-][N+](=O)c1cccc(c1)c2noc(CCCOc3ccc(Cl)cc3Cl)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I11 compound treatment 807318.0 218000.0 0.98 836274.0 241000.0 1.19 1.5338 0.9951 1975001 ChemDiv1_010395 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)N(CCO)Cc3ccccc3)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I12 compound treatment 752852.0 164000.0 0.73 748386.0 153000.0 0.76 1.0535 0.9999 1975002 ChemDiv1_010396 Cc1cccc(OCCn2c(NC(=O)c3cccc(c3)[N+](=O)[O-])nc4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I13 compound treatment 751445.0 162000.0 0.73 748745.0 153000.0 0.76 1.0503 0.9998 1975003 ChemDiv1_010397 CCCCc1nnc(SCC(=O)Nc2ccc(Br)cn2)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I14 compound treatment 776501.0 187000.0 0.84 775758.0 180000.0 0.89 1.2243 0.9995 1473652 ChemDiv1_010398 Fc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I15 compound treatment 758141.0 169000.0 0.76 795969.0 200000.0 0.99 1.237 0.9911 1975004 ChemDiv1_010399 CCCN1C(=O)/C(=C\c2nc3ccccc3c(=O)n2c4ccc(cc4)[N+](=O)[O-])/c5ccccc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I16 compound treatment 793586.0 205000.0 0.92 789760.0 194000.0 0.96 1.3274 0.9997 1975005 ChemDiv1_010400 CCOC(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I17 compound treatment 771509.0 182000.0 0.82 777007.0 181000.0 0.9 1.2128 0.9989 1233201 ChemDiv1_010401 COc1ccc2n(cc(CCN3C(=O)c4ccccc4C3=O)c2c1)C(=O)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I18 compound treatment 790387.0 201000.0 0.9 760261.0 165000.0 0.82 1.2139 0.9987 1975006 ChemDiv1_010402 CCCOC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I19 compound treatment 759288.0 170000.0 0.76 710328.0 115000.0 0.57 0.9406 0.9895 1975007 ChemDiv1_010403 COc1ccc(NC(=O)C2CC(=O)N(C)/C(=N/c3ccc(Cl)c(Cl)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I20 compound treatment 751345.0 162000.0 0.73 719852.0 124000.0 0.62 0.9488 0.9966 1975008 ChemDiv1_010404 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(O)c(OCC)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I21 compound treatment 732732.0 144000.0 0.64 732042.0 136000.0 0.68 0.9326 0.9997 1975009 ChemDiv1_010405 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(OC)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I22 compound treatment 687074.0 98100.0 0.44 692008.0 96300.0 0.48 0.6478 0.9991 1405149 ChemDiv1_010406 CCOC(=O)c1c(CSc2ccc(Cl)cc2)oc3ccc(O)c(CN(C)C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I23 mock treatment 685902.0 96900.0 0.43 688585.0 92900.0 0.46 0.6321 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 I24 mock treatment 531625.0 -57400.0 -0.26 529661.0 -66000.0 -0.33 -0.4129 -0.9929 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J01 compound treatment 617056.0 28000.0 0.13 618952.0 23300.0 0.12 0.1703 0.9991 1975010 ChemDiv1_010407 COc1ccc(CCNC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J02 compound treatment 642419.0 53400.0 0.24 647163.0 51500.0 0.26 0.3494 0.9995 1975011 ChemDiv1_010408 CC(=O)Oc1ccc(cc1)C2Nc3c(ccc([N+](=O)[O-])c3C4C=CCC42)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J03 compound treatment 694258.0 105000.0 0.47 712421.0 117000.0 0.58 0.7421 0.9948 1975012 ChemDiv1_010409 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2cccc(c2)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J04 compound treatment 690442.0 101000.0 0.45 693494.0 97800.0 0.48 0.6637 0.9995 1975013 ChemDiv1_010410 COc1cc(/C=C/2\C(=NN(C2=O)c3ccccc3)O)ccc1Oc4nc(Cl)ncc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J05 compound treatment 737464.0 148000.0 0.66 731410.0 136000.0 0.67 0.9454 1.0 1364207 ChemDiv1_010411 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cc(Br)ccc4F)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J06 compound treatment 4099627.0 3510000.0 15.71 3894589.0 3300000.0 16.34 22.6677 0.9998 1975014 ChemDiv1_010412 CCCCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(CCO)CC4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J07 compound treatment 756014.0 167000.0 0.75 740476.0 145000.0 0.72 1.0358 0.9998 1975015 ChemDiv1_010413 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(Br)ccc3F)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J08 compound treatment 721450.0 132000.0 0.59 746982.0 151000.0 0.75 0.9492 0.9933 1548307 ChemDiv1_010414 COc1cc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4ccccc4o3)cc2)nc(OC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J09 compound treatment 706268.0 117000.0 0.52 749461.0 154000.0 0.76 0.9099 0.9835 1363863 ChemDiv1_010415 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nc3ccccc3o2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J10 compound treatment 747526.0 159000.0 0.71 759430.0 164000.0 0.81 1.0754 0.9978 1629327 ChemDiv1_010416 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccc(Cl)cc4)c5ccccc51 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J11 compound treatment 717256.0 128000.0 0.57 758774.0 163000.0 0.81 0.9773 0.986 1975016 ChemDiv1_010417 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NCCSCc2ccc(C)cc2)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J12 compound treatment 891749.0 303000.0 1.36 787369.0 192000.0 0.95 1.6297 0.9849 1646344 ChemDiv1_010418 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC35C(=O)Nc6ccccc65 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J13 compound treatment 775092.0 186000.0 0.83 754388.0 159000.0 0.79 1.145 0.9996 1975017 ChemDiv1_010419 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J14 compound treatment 737882.0 149000.0 0.67 745747.0 150000.0 0.74 0.9969 0.9985 1975018 ChemDiv1_010420 Cc1ccc(CNC(=O)c2ccc3NC(C4CC=CC4c3c2)c5ccc(cc5)[N+](=O)[O-])cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J15 compound treatment 761858.0 173000.0 0.77 747011.0 151000.0 0.75 1.0772 0.9999 1975019 ChemDiv1_010421 Cc1cc(C)n(n1)C(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J16 compound treatment 735503.0 146000.0 0.66 730336.0 135000.0 0.67 0.9354 1.0 1975020 ChemDiv1_010422 Brc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)NCc3ccco3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J17 compound treatment 768669.0 180000.0 0.8 753422.0 158000.0 0.78 1.1212 0.9999 1975021 ChemDiv1_010423 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(cc3)S(=O)(=O)N)C)ccc1OC(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J18 compound treatment 752165.0 163000.0 0.73 719288.0 124000.0 0.61 0.9494 0.9962 1975022 ChemDiv1_010424 Cc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)NCc3ccccc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J19 compound treatment 766818.0 178000.0 0.8 706676.0 111000.0 0.55 0.9516 0.9837 1975023 ChemDiv1_010425 COc1ccccc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J20 compound treatment 741176.0 152000.0 0.68 703046.0 107000.0 0.53 0.8578 0.9925 1975024 ChemDiv1_010426 Cc1nc(SCC(=O)Nc2cccc(c2)C(=O)O)c(C#N)c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J21 compound treatment 767861.0 179000.0 0.8 714034.0 118000.0 0.59 0.9807 0.9883 1312709 ChemDiv1_010427 O=C1CSC(N1Cc2cccnc2)c3cn(nc3c4cc5ccccc5oc4=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J22 compound treatment 707754.0 119000.0 0.53 696991.0 101000.0 0.5 0.7308 0.9996 1975025 ChemDiv1_010428 O=C(NCCc1c[nH]c2ccccc12)/C(=C/c3cccs3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J23 mock treatment 699563.0 111000.0 0.49 700635.0 105000.0 0.52 0.7176 0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 J24 mock treatment 527028.0 -62000.0 -0.28 522208.0 -73500.0 -0.36 -0.4535 -0.991 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K01 compound treatment 609274.0 20300.0 0.09 615894.0 20200.0 0.1 0.135 0.9988 1368628 ChemDiv1_010429 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K02 compound treatment 660992.0 72000.0 0.32 686923.0 91300.0 0.45 0.5475 0.9862 1975026 ChemDiv1_010430 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)/C(=N/c4ccc(OC)cc4)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K03 compound treatment 753952.0 165000.0 0.74 733417.0 138000.0 0.68 1.0046 0.9992 1486358 ChemDiv1_010431 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3c(=O)c(Oc4cccc(C)c4)coc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K04 compound treatment 679808.0 90800.0 0.41 697536.0 102000.0 0.5 0.6442 0.9942 1975027 ChemDiv1_010432 CCOc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)Nc3ccc(Br)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K05 compound treatment 722921.0 134000.0 0.6 731260.0 136000.0 0.67 0.8988 0.9984 1975028 ChemDiv1_010433 Oc1ccc2c(=O)c(c3cccc(Cl)c3)c(oc2c1CN4CCOCC4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K06 compound treatment 682665.0 93700.0 0.42 722531.0 127000.0 0.63 0.7408 0.9806 1975029 ChemDiv1_010434 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3cccc(F)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K07 compound treatment 669705.0 80700.0 0.36 699046.0 103000.0 0.51 0.6175 0.9854 1975030 ChemDiv1_010435 COCCCNc1nc(nc2ccccc12)c3ccc(cc3)C(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K08 compound treatment 711905.0 123000.0 0.55 746573.0 151000.0 0.75 0.9176 0.9886 1669342 ChemDiv1_010436 Clc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)N5CCOCC5)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K09 compound treatment 734466.0 145000.0 0.65 802378.0 207000.0 1.02 1.1845 0.9761 1975031 ChemDiv1_010437 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(c3)C(F)(F)F)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K10 compound treatment 732743.0 144000.0 0.64 756489.0 161000.0 0.8 1.0183 0.9944 1486772 ChemDiv1_010438 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K11 compound treatment 3767157.0 3180000.0 14.23 3964197.0 3370000.0 16.69 21.8592 0.9968 1975032 ChemDiv1_010439 OC(=O)CC(N1C(=O)/C(=C/c2ccc(o2)c3ccc(Br)cc3)/SC1=S)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K12 compound treatment 733936.0 145000.0 0.65 698439.0 103000.0 0.51 0.8187 0.9928 1975033 ChemDiv1_010440 Cc1cccc(OCCn2c(NC(=O)c3ccc(cc3)[N+](=O)[O-])nc4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K13 compound treatment 714304.0 125000.0 0.56 736294.0 141000.0 0.7 0.8892 0.9942 1975034 ChemDiv1_010441 CCCCc1nnc(SCC(=O)NC2CCCCC2)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K14 compound treatment 712147.0 123000.0 0.55 742288.0 147000.0 0.73 0.9033 0.9907 1417307 ChemDiv1_010442 Cc1ccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K15 compound treatment 752224.0 163000.0 0.73 759729.0 164000.0 0.81 1.0913 0.9986 1975035 ChemDiv1_010443 COc1ccc(cc1)n2c(/C=C\3/C(=O)N(C)c4ccc(Br)cc34)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K16 compound treatment 814357.0 225000.0 1.01 827269.0 232000.0 1.15 1.5245 0.9979 1975036 ChemDiv1_010444 COC(=O)c1cccc(c1)c2ccc(/C=C/3\C(=O)N(N=C3C(F)(F)F)c4ccc(cc4)S(=O)(=O)N)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K17 compound treatment 745880.0 157000.0 0.7 750089.0 154000.0 0.76 1.0374 0.9991 1243779 ChemDiv1_010445 Clc1ccc(cc1)C(=O)NCCc2c[nH]c3ccc(OCc4ccccc4)cc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K18 compound treatment 708050.0 119000.0 0.53 734752.0 139000.0 0.69 0.864 0.9919 1975037 ChemDiv1_010446 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(cc3)N(C)C)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K19 compound treatment 753616.0 165000.0 0.74 722888.0 127000.0 0.63 0.9666 0.997 1975038 ChemDiv1_010447 CCN/1C(=O)CC(S\C1=N/c2ccc(cc2)C(=O)OC)C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K20 compound treatment 725705.0 137000.0 0.61 719299.0 124000.0 0.61 0.8657 1.0 1723367 ChemDiv1_010448 CCOC(=O)c1c(CN(C)c2ccccc2)oc3cc(Br)c(O)c(CN(C)C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K21 compound treatment 729458.0 140000.0 0.63 741632.0 146000.0 0.72 0.9558 0.9976 1975039 ChemDiv1_010449 CCOc1ccc(NC(=O)C2CC(=O)N(Cc3ccc4OCOc4c3)/C(=N/c5ccccc5)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K22 compound treatment 670813.0 81800.0 0.37 670682.0 75000.0 0.37 0.5217 1.0 1474146 ChemDiv1_010450 CCOC(=O)c1c(CSc2ccc(CC)cc2)oc3ccc(O)c(CN(C)C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K23 mock treatment 697732.0 109000.0 0.49 695524.0 99900.0 0.49 0.6939 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 K24 mock treatment 527562.0 -61500.0 -0.28 520992.0 -74700.0 -0.37 -0.4561 -0.9894 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L01 compound treatment 634715.0 45700.0 0.2 601799.0 6130.0 0.03 0.1661 0.8033 1975040 ChemDiv1_010451 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L02 compound treatment 799173.0 210000.0 0.94 772800.0 177000.0 0.88 1.2857 0.9994 1427968 ChemDiv1_010452 CC(=O)Oc1ccc(C2Nc3ccc(cc3C4C=CCC42)C(=O)O)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L03 compound treatment 713960.0 125000.0 0.56 704668.0 109000.0 0.54 0.7773 0.9998 1975041 ChemDiv1_010453 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)c3ccc(OC)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L04 compound treatment 719128.0 130000.0 0.58 687730.0 92100.0 0.46 0.7343 0.9927 1571986 ChemDiv1_010454 Clc1ccc(cc1NC(=O)COc2ccc(Br)cc2)c3nc4ncccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L05 compound treatment 707453.0 118000.0 0.53 693081.0 97400.0 0.48 0.7161 0.9989 1871399 ChemDiv1_010455 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L06 compound treatment 2009516.0 1420000.0 6.36 1905419.0 1310000.0 6.49 9.0842 0.9999 1975042 ChemDiv1_010456 CC1CCN(CC1)c2nc3ccccn3c(=O)c2/C=C\4/SC(=S)N(C5CCCCC5)C4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L07 compound treatment 761756.0 173000.0 0.77 709748.0 114000.0 0.57 0.9464 0.9881 1168489 ChemDiv1_010457 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4coc5ccc(C)cc5c4=O)C(=O)OC6CCCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L08 compound treatment 750521.0 162000.0 0.72 722131.0 126000.0 0.63 0.9542 0.9975 1932340 ChemDiv1_010458 CN(C)c1nc(nc(n1)N2CC(=O)N(C2=N)c3ccccc3)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L09 compound treatment 655762.0 66700.0 0.3 717891.0 122000.0 0.61 0.6394 0.947 1174931 ChemDiv1_010459 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nc3ccccc3[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L10 compound treatment 701139.0 112000.0 0.5 728439.0 133000.0 0.66 0.82 0.9911 1432485 ChemDiv1_010460 OC1(CC(=O)c2ccco2)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L11 compound treatment 753987.0 165000.0 0.74 755666.0 160000.0 0.79 1.0826 0.9994 1975043 ChemDiv1_010461 COc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L12 compound treatment 762883.0 174000.0 0.78 750790.0 155000.0 0.77 1.0937 1.0 1124003 ChemDiv1_010462 COc1ccc(cc1)C2=NN3C(C2)c4cc(Br)ccc4OC35C(=O)N(CC=C)c6ccccc65 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L13 compound treatment 733657.0 145000.0 0.65 706661.0 111000.0 0.55 0.8466 0.9967 1975044 ChemDiv1_010463 COc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCN(CC2)c3ccccc3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L14 compound treatment 742322.0 153000.0 0.69 710637.0 115000.0 0.57 0.888 0.9957 1975045 ChemDiv1_010464 CCOC(=O)c1sc(NC(=O)CSc2nnc(CC)[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L15 compound treatment 789392.0 200000.0 0.9 740402.0 145000.0 0.72 1.1412 0.9938 1975046 ChemDiv1_010465 FC(F)(F)c1cc(NC(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O)ccc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L16 compound treatment 754731.0 166000.0 0.74 731465.0 136000.0 0.67 1.0002 0.9988 1975047 ChemDiv1_010466 COc1ccc(cc1)C(=O)N2CCN(CCNC(=O)C(=O)Nc3ccc(C)cc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L17 compound treatment 743414.0 154000.0 0.69 731760.0 136000.0 0.67 0.9654 0.9999 1975048 ChemDiv1_010467 COc1cc(/C=C/2\C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OC(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L18 compound treatment 734869.0 146000.0 0.65 695579.0 99900.0 0.49 0.8116 0.9907 1500804 ChemDiv1_010468 CN(C)c1ccc(cc1)C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L19 compound treatment 751954.0 163000.0 0.73 729689.0 134000.0 0.66 0.9852 0.9989 1975049 ChemDiv1_010469 CCOC(=O)c1ccc(NC(=O)CC2S/C(=N\C)/N(C)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L20 compound treatment 702196.0 113000.0 0.51 678564.0 82900.0 0.41 0.6486 0.9946 1975050 ChemDiv1_010470 CC(C)Cc1ccc(C#N)c(SCc2nnc(o2)c3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L21 compound treatment 744251.0 155000.0 0.69 733188.0 138000.0 0.68 0.9731 1.0 1975051 ChemDiv1_010471 O=C1CSC(N1CC2COc3ccccc3O2)c4cn(nc4c5cc6ccccc6oc5=O)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L22 compound treatment 703701.0 115000.0 0.51 673991.0 78300.0 0.39 0.6374 0.9905 1871345 ChemDiv1_010472 COc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L23 mock treatment 693575.0 105000.0 0.47 695776.0 100000.0 0.5 0.6816 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 L24 mock treatment 503961.0 -85100.0 -0.38 538056.0 -57600.0 -0.29 -0.471 -0.9899 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M01 compound treatment 617882.0 28900.0 0.13 594886.0 -784.0 0.0 0.0886 0.6856 1141931 ChemDiv1_010473 Clc1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M02 compound treatment 654930.0 65900.0 0.3 652604.0 56900.0 0.28 0.4081 0.9997 1975052 ChemDiv1_010474 COc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccc(OC)c(OC)c3)C(=O)Nc4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M03 compound treatment 702702.0 114000.0 0.51 717064.0 121000.0 0.6 0.7851 0.9966 1324517 ChemDiv1_010475 CCCNC(=O)Nc1nc(CC(=O)OCC)cs1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M04 compound treatment 652714.0 63700.0 0.29 690378.0 94700.0 0.47 0.5334 0.9715 1975053 ChemDiv1_010476 CCN/1C(=O)CC(S\C1=N/c2cccc(F)c2)C(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M05 compound treatment 681941.0 92900.0 0.42 725421.0 130000.0 0.64 0.7486 0.9778 1975054 ChemDiv1_010477 COc1ccc(Oc2c(oc3c(CN4CCCCC4C)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M06 compound treatment 702948.0 114000.0 0.51 713965.0 118000.0 0.59 0.775 0.9976 1975055 ChemDiv1_010478 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccccc3OC)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M07 compound treatment 715177.0 126000.0 0.56 740226.0 145000.0 0.72 0.9057 0.9931 1672057 ChemDiv1_010479 CC(C)(C)c1ccc(cc1)c2nc(NCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M08 compound treatment 756584.0 168000.0 0.75 734198.0 139000.0 0.69 1.0157 0.999 1691574 ChemDiv1_010480 COC(=O)c1cccc2C3C=CCC3C(Nc12)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M09 compound treatment 713866.0 125000.0 0.56 720960.0 125000.0 0.62 0.8341 0.9986 1975056 ChemDiv1_010481 CCN(CCO)C(=O)CCN1C(=O)/C(=C/c2cccs2)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M10 compound treatment 704972.0 116000.0 0.52 731338.0 136000.0 0.67 0.8423 0.9919 1661010 ChemDiv1_010482 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3(CCCC3)c4ccccc4)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M11 compound treatment 760993.0 172000.0 0.77 773216.0 178000.0 0.88 1.1663 0.9978 1975057 ChemDiv1_010483 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3ccc(O)c(c3)C(=O)O)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M12 compound treatment 714008.0 125000.0 0.56 699955.0 104000.0 0.52 0.7609 0.9992 1603477 ChemDiv1_010484 Cc1ccc(OCCn2c(NC(=O)c3ccc(Cl)cc3)nc4ccccc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M13 compound treatment 729634.0 141000.0 0.63 729028.0 133000.0 0.66 0.9122 0.9997 1975058 ChemDiv1_010485 CCCCc1nnc(SCC(=O)Nc2cc(C)on2)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M14 compound treatment 711349.0 122000.0 0.55 716920.0 121000.0 0.6 0.8119 0.9989 1699901 ChemDiv1_010486 Cc1cccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M15 compound treatment 736434.0 147000.0 0.66 763233.0 168000.0 0.83 1.0536 0.9935 1975059 ChemDiv1_010487 Cc1c(C)c2ccccc2n1C(=O)CSc3nnc(o3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M16 compound treatment 580205.0 -8810.0 -0.04 594700.0 -970.0 0.0 -0.0313 -0.7874 1975060 ChemDiv1_010488 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M17 compound treatment 715889.0 127000.0 0.57 742163.0 146000.0 0.73 0.9147 0.9926 1975061 ChemDiv1_010489 C(CSSCCNCCc1c[nH]c2ccccc12)NCCc3c[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M18 compound treatment 742630.0 154000.0 0.69 685760.0 90100.0 0.45 0.8018 0.9781 1975062 ChemDiv1_010490 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc4OCOc4c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M19 compound treatment 754855.0 166000.0 0.74 727686.0 132000.0 0.65 0.9874 0.998 1975063 ChemDiv1_010491 CCN/1C(=O)CC(S\C1=N/c2cccc(Cl)c2)C(=O)Nc3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M20 compound treatment 719218.0 130000.0 0.58 693230.0 97600.0 0.48 0.7539 0.9957 1975064 ChemDiv1_010492 CCOC(=O)c1c(oc2ccc(O)cc12)c3cc(Br)c(OC)c(Br)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M21 compound treatment 738764.0 150000.0 0.67 718983.0 123000.0 0.61 0.906 0.9989 1975065 ChemDiv1_010493 CCCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(F)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M22 compound treatment 686986.0 98000.0 0.44 669700.0 74000.0 0.37 0.5694 0.996 1975066 ChemDiv1_010494 CC(=C)C(=O)OCCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M23 mock treatment 694743.0 106000.0 0.47 673628.0 78000.0 0.39 0.6077 0.9949 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 M24 mock treatment 554049.0 -35000.0 -0.16 426711.0 -169000.0 -0.84 -0.7025 -0.825 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N01 compound treatment 613989.0 25000.0 0.11 602856.0 7190.0 0.04 0.1042 0.8883 1975067 ChemDiv1_010495 Cc1cccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)S(=O)(=O)c4ccccc4)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N02 compound treatment 738531.0 150000.0 0.67 711984.0 116000.0 0.58 0.8807 0.9972 1247981 ChemDiv1_010496 CC(=O)Oc1ccc(C2Nc3ccc(C)cc3C4C=CCC42)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N03 compound treatment 685565.0 96600.0 0.43 678798.0 83100.0 0.41 0.5968 0.9997 1975068 ChemDiv1_010497 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(F)(F)F)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N04 compound treatment 692548.0 104000.0 0.46 678522.0 82900.0 0.41 0.6179 0.9982 1975069 ChemDiv1_010498 CCCCOc1cccc(c1)C(=O)Nc2cc(ccc2Cl)c3nc4ncccc4o3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N05 compound treatment 716856.0 128000.0 0.57 722623.0 127000.0 0.63 0.8494 0.9989 1975070 ChemDiv1_010499 CCSCCOC(=O)C1=C(C)NC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C2)c4ccccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N06 compound treatment 3475436.0 2890000.0 12.92 3505346.0 2910000.0 14.41 19.3285 0.9985 1975071 ChemDiv1_010500 CC(N1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCN(C)CC4)/SC1=S)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N07 compound treatment 703347.0 114000.0 0.51 700859.0 105000.0 0.52 0.7304 1.0 1410739 ChemDiv1_010501 Clc1ccc2nc(NCCN3CCOCC3)nc(c4ccccc4)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N08 compound treatment 723609.0 135000.0 0.6 694598.0 98900.0 0.49 0.7726 0.9947 1975072 ChemDiv1_010502 CC(=O)c1cccc(c1)N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N09 compound treatment 716042.0 127000.0 0.57 744705.0 149000.0 0.74 0.9241 0.9917 1272241 ChemDiv1_010503 CCOC(=O)c1sc(NC(=O)C(CC)Sc2nccn2C)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N10 compound treatment 716171.0 127000.0 0.57 694033.0 98400.0 0.49 0.747 0.997 1118978 ChemDiv1_010504 OC1(CC(=O)c2cccs2)C(=O)N(Cc3ccc(Cl)cc3)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N11 compound treatment 743580.0 155000.0 0.69 746094.0 150000.0 0.75 1.0162 0.9993 1975073 ChemDiv1_010505 Cc1cccc(N(CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)S(=O)(=O)c4ccccc4)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N12 compound treatment 937774.0 349000.0 1.56 851103.0 255000.0 1.27 1.9987 0.9946 1975074 ChemDiv1_010506 Brc1ccc2OC(N3N=C(CC3c2c1)c4ccco4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N13 compound treatment 729607.0 141000.0 0.63 712058.0 116000.0 0.58 0.8527 0.999 1975075 ChemDiv1_010507 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N14 compound treatment 702641.0 114000.0 0.51 683288.0 87600.0 0.43 0.6666 0.9969 1260330 ChemDiv1_010508 C=CCn1c2ccccc2c3nnc(SCC(=O)Nc4nc5ccccc5s4)nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N15 compound treatment 720524.0 132000.0 0.59 730690.0 135000.0 0.67 0.8892 0.998 1975076 ChemDiv1_010509 O=C(C(Cc1ccccc1)N2C(=O)C3CCCCC3C2=O)N4CCN(Cc5ccc6OCOc6c5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N16 compound treatment 719321.0 130000.0 0.58 696438.0 101000.0 0.5 0.7654 0.997 1975077 ChemDiv1_010510 Fc1cccc(c1)C(=O)N2CCN(CCNC(=O)C(=O)Nc3ccccc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N17 compound treatment 736294.0 147000.0 0.66 746815.0 151000.0 0.75 0.9956 0.998 1975078 ChemDiv1_010511 CCOCCOC(=O)C(C)Oc1ccc2c(=O)c(Oc3ccccc3Cl)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N18 compound treatment 733645.0 145000.0 0.65 704910.0 109000.0 0.54 0.8405 0.996 1551699 ChemDiv1_010512 COc1ccc(C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N19 compound treatment 728626.0 140000.0 0.62 723593.0 128000.0 0.63 0.89 1.0 1975079 ChemDiv1_010513 CCOC(=O)c1ccccc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N20 compound treatment 745972.0 157000.0 0.7 694508.0 98800.0 0.49 0.843 0.9844 1198296 ChemDiv1_010514 CCCCc1ccc2c(N)c(sc2n1)C(=O)Nc3ccc(cc3)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N21 compound treatment 731654.0 143000.0 0.64 689726.0 94100.0 0.47 0.781 0.988 1975080 ChemDiv1_010515 CC(=O)Oc1ccc(C2Nc3ccc(cc3C4C=CCC42)C(=O)C)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N22 compound treatment 700773.0 112000.0 0.5 665038.0 69400.0 0.34 0.5967 0.9832 1871355 ChemDiv1_010516 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N23 mock treatment 668892.0 79900.0 0.36 677836.0 82200.0 0.41 0.5407 0.9979 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 N24 mock treatment 406705.0 -182000.0 -0.82 185142.0 -411000.0 -2.03 -2.0151 -0.9196 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O01 compound treatment 624170.0 35200.0 0.16 618258.0 22600.0 0.11 0.1904 0.986 1233473 ChemDiv1_010517 Clc1ccc(cc1)c2nc(NCc3ccco3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O02 compound treatment 680392.0 91400.0 0.41 607766.0 12100.0 0.06 0.3316 0.8021 1975081 ChemDiv1_010518 CCN/1C(=O)CC(S\C1=N/c2ccc3OCOc3c2)C(=O)Nc4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O03 compound treatment 684321.0 95300.0 0.43 650927.0 55300.0 0.27 0.4952 0.977 1331525 ChemDiv1_010519 CC(C)c1nnc(NC(=O)CCN2C(=O)c3ccccc3C2=O)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O04 compound treatment 651921.0 62900.0 0.28 655170.0 59500.0 0.29 0.4075 0.9997 1975082 ChemDiv1_010520 CCOc1ccc(NC(=O)C2CC(=O)N(CC)/C(=N/c3ccc(C)c(C)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O05 compound treatment 723594.0 135000.0 0.6 697107.0 101000.0 0.5 0.7813 0.9959 1924256 ChemDiv1_010521 COc1ccc(Oc2c(oc3c(CN4CCCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O06 compound treatment 648559.0 59500.0 0.27 628209.0 32500.0 0.16 0.3025 0.971 1975083 ChemDiv1_010522 CCN/1C(=O)CC(S\C1=N/c2cccc(c2)C(F)(F)F)C(=O)Nc3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O07 compound treatment 635383.0 46400.0 0.21 655491.0 59800.0 0.3 0.3563 0.9848 1975084 ChemDiv1_010523 CC(C)(C)c1ccc(cc1)c2nc(NCCCN3CCOCC3)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O08 compound treatment 650690.0 61700.0 0.28 664909.0 69200.0 0.34 0.4378 0.9942 1176027 ChemDiv1_010524 CCOc1ccc(cc1Br)C(=O)Nc2ccc3oc(nc3c2)c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O09 compound treatment 666945.0 77900.0 0.35 687976.0 92300.0 0.46 0.57 0.9911 1975085 ChemDiv1_010525 OCCN(Cc1ccccc1)C(=O)CCN2C(=O)/C(=C/c3cccs3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O10 compound treatment 676998.0 88000.0 0.39 654415.0 58700.0 0.29 0.4843 0.9889 1251763 ChemDiv1_010526 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc3nc(oc3c2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O11 compound treatment 692147.0 103000.0 0.46 703922.0 108000.0 0.54 0.7056 0.9972 1975086 ChemDiv1_010527 COc1ccc(/C=C/2\SC(=S)N(CCC(=O)Nc3cccc(c3)C(=O)O)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O12 compound treatment 664342.0 75300.0 0.34 649695.0 54000.0 0.27 0.4277 0.9935 1975087 ChemDiv1_010528 [O-][N+](=O)c1cccc(c1)C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O13 compound treatment 696277.0 107000.0 0.48 686312.0 90600.0 0.45 0.657 0.9994 1975088 ChemDiv1_010529 CC(C)Cc1nnc(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O14 compound treatment 672060.0 83000.0 0.37 663670.0 68000.0 0.34 0.5011 0.9988 1526256 ChemDiv1_010530 O=C(Nc1nc2ccccc2n1CCOc3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O15 compound treatment 694463.0 105000.0 0.47 705136.0 109000.0 0.54 0.7172 0.9976 1663697 ChemDiv1_010531 COC(=O)C1CCN(CC1)C(=O)c2cc(nc3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O16 compound treatment 684564.0 95500.0 0.43 677464.0 81800.0 0.41 0.589 0.9996 1975089 ChemDiv1_010532 NS(=O)(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc(cc4)S(=O)(=O)N)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O17 compound treatment 727061.0 138000.0 0.62 686796.0 91100.0 0.45 0.7562 0.9881 1176133 ChemDiv1_010533 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3[nH]cc(CCN4C(=O)c5ccccc5C4=O)c3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O18 compound treatment 697218.0 108000.0 0.48 658187.0 62500.0 0.31 0.5615 0.9767 1975090 ChemDiv1_010534 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3c[nH]c4ccccc34)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O19 compound treatment 689234.0 100000.0 0.45 684228.0 88600.0 0.44 0.6274 0.9999 1975091 ChemDiv1_010535 COc1ccc(NC(=O)C2CC(=O)N(CC=C)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O20 compound treatment 674739.0 85700.0 0.38 641743.0 46100.0 0.23 0.4327 0.9692 1731326 ChemDiv1_010536 CCOC(=O)c1c(CSc2ccccn2)n(C)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O21 compound treatment 707494.0 118000.0 0.53 684442.0 88800.0 0.44 0.686 0.9957 1975092 ChemDiv1_010537 COC(=O)c1ccc(NC(=O)C2CC(=O)N(CC=C)/C(=N/c3ccc(Cl)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O22 compound treatment 655051.0 66000.0 0.3 631416.0 35700.0 0.18 0.3342 0.97 1432108 ChemDiv1_010538 Cc1cc(C)c(NS(=O)(=O)c2ccc(NC(=O)c3sc4ccccc4c3Cl)cc2)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O23 mock treatment 647124.0 58100.0 0.26 640088.0 44400.0 0.22 0.3395 0.9965 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 O24 mock treatment 446350.0 -143000.0 -0.64 412714.0 -183000.0 -0.91 -1.0924 -0.9853 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P01 compound treatment 581986.0 -7030.0 -0.03 579814.0 -15900.0 -0.08 -0.0778 -0.9193 1975093 ChemDiv1_010539 COc1cccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P02 compound treatment 597435.0 8420.0 0.04 593747.0 -1920.0 -0.01 0.0199 0.5123 1975094 ChemDiv1_010540 Clc1ccc(cc1)C2Nc3ccc(cc3C4C=CCC42)C(=O)/C=C/c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P03 compound treatment 608425.0 19400.0 0.09 600081.0 4410.0 0.02 0.0769 0.8582 1975095 ChemDiv1_010541 COCCOC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)C(F)(F)F)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P04 compound treatment 620692.0 31700.0 0.14 611871.0 16200.0 0.08 0.157 0.9637 1624744 ChemDiv1_010542 O=S1(=O)C=C(Sc2nc3ccccc3o2)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P05 compound treatment 593543.0 4530.0 0.02 604415.0 8750.0 0.04 0.045 0.9401 1975096 ChemDiv1_010543 CCOCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)cc3)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P06 compound treatment 974991.0 386000.0 1.73 967703.0 372000.0 1.84 2.5249 0.9995 1975097 ChemDiv1_010544 COCCCN1C(=O)/C(=C\c2c(nc3c(C)cccn3c2=O)N4CC(C)OC(C)C4)/SC1=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P07 compound treatment 605189.0 16200.0 0.07 615996.0 20300.0 0.1 0.1224 0.9869 1603929 ChemDiv1_010545 COC(=O)Nc1nc2cc(Cl)c(Oc3ccc4ccccc4c3Cl)cc2[nH]1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P08 compound treatment 603432.0 14400.0 0.06 617151.0 21500.0 0.11 0.1209 0.9713 1484881 ChemDiv1_010546 OC1(CC(=O)c2cc3ccccc3oc2=O)C(=O)Nc4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P09 compound treatment 611464.0 22400.0 0.1 626529.0 30900.0 0.15 0.1792 0.9793 1233662 ChemDiv1_010547 CCOC(=O)c1sc(NC(=O)CSc2nnc(C)c(=O)[nH]2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P10 compound treatment 582390.0 -6620.0 -0.03 606083.0 10400.0 0.05 0.0155 0.2607 1234770 ChemDiv1_010548 COc1ccc(cc1OC)C(=O)CC2(O)C(=O)Nc3ccc(C)cc32 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P11 compound treatment 620492.0 31500.0 0.14 609120.0 13500.0 0.07 0.1468 0.9415 1975098 ChemDiv1_010549 Cc1c(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P12 compound treatment 626626.0 37600.0 0.17 617029.0 21400.0 0.11 0.1939 0.9749 1460653 ChemDiv1_010550 COc1ccc(cc1OC)c2cc(C(=O)Nc3ccccc3C(=O)O)c4ccccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P13 compound treatment 601424.0 12400.0 0.06 607311.0 11600.0 0.06 0.0801 0.9998 1626245 ChemDiv1_010551 COc1ccc(cc1OC)c2noc(COc3ccc(Cl)cc3Cl)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P14 compound treatment 611026.0 22000.0 0.1 602377.0 6710.0 0.03 0.0932 0.896 1788973 ChemDiv1_010552 CSc1nnc-2c(OC(Nc3ccccc32)c4ccc(cc4)[N+](=O)[O-])n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P15 compound treatment 617158.0 28100.0 0.13 620098.0 24400.0 0.12 0.1747 0.9998 1975099 ChemDiv1_010553 Cc1cc(C)nc(NC(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P16 compound treatment 627551.0 38500.0 0.17 623931.0 28300.0 0.14 0.221 0.9946 1975100 ChemDiv1_010554 CCc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc(C)cc3)CC2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P17 compound treatment 640317.0 51300.0 0.23 610288.0 14600.0 0.07 0.2136 0.887 1975101 ChemDiv1_010555 CCOCCOC(=O)COc1ccc2c(=O)c(Oc3cc(C)c(Cl)c(C)c3)coc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P18 compound treatment 620832.0 31800.0 0.14 600444.0 4770.0 0.02 0.1174 0.8134 1401069 ChemDiv1_010556 CCCc1ccc(C#N)c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P19 compound treatment 637950.0 48900.0 0.22 602980.0 7310.0 0.04 0.1805 0.813 1975102 ChemDiv1_010557 CCOC(=O)c1c(C)c(C)sc1NC(=O)CC2S/C(=N\C)/N(C)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P20 compound treatment 615195.0 26200.0 0.12 599932.0 4260.0 0.02 0.0978 0.8213 1975103 ChemDiv1_010558 COc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)Nc3cc(C)on3)n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P21 compound treatment 622105.0 33100.0 0.15 641492.0 45800.0 0.23 0.2653 0.9786 1445243 ChemDiv1_010559 CC(=O)Oc1ccc(C2Nc3c(cccc3C4C=CCC42)C(=O)O)c(OC(=O)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P22 compound treatment 615148.0 26100.0 0.12 591179.0 -4490.0 -0.02 0.067 0.5626 1871396 ChemDiv1_010560 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P23 mock treatment 567428.0 -21600.0 -0.1 605033.0 9360.0 0.05 -0.0355 -0.3315 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.616 P24 mock treatment 301493.0 -288000.0 -1.29 442864.0 -153000.0 -0.76 -1.4453 -0.968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A01 compound treatment 610084.0 22900.0 0.1 576843.0 15200.0 0.08 0.1255 0.9883 1871199 ChemDiv1_010561 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A02 compound treatment 598666.0 11500.0 0.05 586935.0 25200.0 0.13 0.1248 0.9227 1975104 ChemDiv1_010562 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3cccc(OCc4ccccc4)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A03 compound treatment 620908.0 33700.0 0.15 592985.0 31300.0 0.16 0.2164 0.9999 1975105 ChemDiv1_010563 COc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A04 compound treatment 612492.0 25300.0 0.11 593280.0 31600.0 0.16 0.1907 0.9874 1975106 ChemDiv1_010564 NC1=C(C#N)C(c2ccc(Cl)c(c2)[N+](=O)[O-])c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A05 compound treatment 584135.0 -3060.0 -0.01 575938.0 14200.0 0.07 0.0402 0.5597 1871237 ChemDiv1_010565 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A06 compound treatment 627490.0 40300.0 0.18 618504.0 56800.0 0.28 0.3266 0.9769 1932635 ChemDiv1_010566 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)c(Cl)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A07 compound treatment 686414.0 99200.0 0.44 648516.0 86800.0 0.43 0.6182 0.9999 1724137 ChemDiv1_010567 NC1=C(C#N)C(c2ccc(Br)s2)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A08 compound treatment 666411.0 79200.0 0.35 620461.0 58800.0 0.29 0.4566 0.9952 1285413 ChemDiv1_010568 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(Cl)cc4Cl)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A09 compound treatment 683322.0 96100.0 0.43 613954.0 52300.0 0.26 0.4874 0.9704 1975107 ChemDiv1_010569 Cc1cc(c(C#N)c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A10 compound treatment 688295.0 101000.0 0.45 634159.0 72500.0 0.36 0.5739 0.9934 1975108 ChemDiv1_010570 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A11 compound treatment 673172.0 86000.0 0.38 615328.0 53600.0 0.27 0.46 0.9836 1975109 ChemDiv1_010571 CC(=O)c1cc(C#N)c(SCC(=O)NC2(CC3CC4CC(C3)C2)C4)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A12 compound treatment 682766.0 95600.0 0.43 660141.0 98500.0 0.49 0.6474 0.9979 1292071 ChemDiv1_010572 CCOC(=O)C1=C(N)OC(=C(C(=O)OCC)C21C(=O)Nc3ccccc32)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A13 compound treatment 646938.0 59700.0 0.27 657469.0 95800.0 0.47 0.5246 0.9632 1975110 ChemDiv1_010573 COC(=O)C1=C(C)OC(=C(C#N)C1c2cc(cs2)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A14 compound treatment 671037.0 83800.0 0.38 687544.0 126000.0 0.62 0.7063 0.9705 1975111 ChemDiv1_010574 CC(C)N1C/C(=C\c2ccc(F)cc2)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A15 compound treatment 686531.0 99300.0 0.44 653091.0 91400.0 0.45 0.6346 1.0 1975112 ChemDiv1_010575 Cc1csc(NC(=O)CSc2nc(cc(c3cccs3)c2C#N)c4cccs4)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A16 compound treatment 666416.0 79200.0 0.35 667051.0 105000.0 0.52 0.6198 0.9823 1975113 ChemDiv1_010576 CC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCC=C)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A17 compound treatment 672862.0 85700.0 0.38 648529.0 86800.0 0.43 0.5754 0.9984 1975114 ChemDiv1_010577 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(F)c(Br)c2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A18 compound treatment 652631.0 65400.0 0.29 639519.0 77800.0 0.39 0.4798 0.9908 1975115 ChemDiv1_010578 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A19 compound treatment 685975.0 98800.0 0.44 656302.0 94600.0 0.47 0.6441 0.9996 1975116 ChemDiv1_010579 CCCCOC(=O)c1ccc(NCN2C(=O)S/C(=C\c3ccc(O)c(OC)c3)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A20 compound treatment 688535.0 101000.0 0.45 680124.0 118000.0 0.59 0.7356 0.9919 1727219 ChemDiv1_010580 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3cccc(OCc4ccccc4)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A21 compound treatment 621284.0 34100.0 0.15 625935.0 64200.0 0.32 0.333 0.9433 1975117 ChemDiv1_010581 [O-][N+](=O)c1cccc(NC(=O)CSc2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])s2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A22 compound treatment 622595.0 35400.0 0.16 613108.0 51400.0 0.25 0.2922 0.9739 1975118 ChemDiv1_010582 COc1ccc(Br)cc1C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A23 mock treatment 599660.0 12500.0 0.06 591723.0 30000.0 0.15 0.1447 0.9104 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 A24 mock treatment 481892.0 -105000.0 -0.47 520453.0 -41200.0 -0.2 -0.4777 -0.93 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B01 compound treatment 578545.0 -8650.0 -0.04 566709.0 5020.0 0.02 -0.0098 -0.2126 1975119 ChemDiv1_010583 Cc1cccc(NC(=O)CSc2nc(N)c(C#N)c(c3cccs3)c2C#N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B02 compound treatment 621624.0 34400.0 0.15 620110.0 58400.0 0.29 0.3136 0.9565 1975120 ChemDiv1_010584 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)S(=O)(=O)N3CCCCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B03 compound treatment 670528.0 83300.0 0.37 650063.0 88400.0 0.44 0.5733 0.9968 1975121 ChemDiv1_010585 Nc1nc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])c(C#N)c(c1C#N)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B04 compound treatment 686580.0 99400.0 0.44 680100.0 118000.0 0.59 0.7294 0.9907 1324637 ChemDiv1_010586 CCc1cc2c(=O)n3CCc4c([nH]c5ccc(OC)cc45)-c3nc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B05 compound treatment 1057303.0 470000.0 2.1 1202330.0 641000.0 3.17 3.7321 0.9801 1975122 ChemDiv1_010587 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccccc4OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B06 compound treatment 696840.0 110000.0 0.49 667163.0 105000.0 0.52 0.7165 0.9995 1651242 ChemDiv1_010588 CC1=C(C)C2C3C(C1c4ccccc24)C(=O)N(Cc5ccc(Br)cc5)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B07 compound treatment 772015.0 185000.0 0.83 732137.0 170000.0 0.84 1.1821 0.9999 1975123 ChemDiv1_010589 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccs3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B08 compound treatment 730092.0 143000.0 0.64 697208.0 136000.0 0.67 0.927 0.9997 1975124 ChemDiv1_010590 CC1=NN(C(=O)C1=CNc2c(Cl)cc(Cl)cc2Cl)c3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B09 compound treatment 871624.0 284000.0 1.27 855814.0 294000.0 1.46 1.9306 0.9977 1975125 ChemDiv1_010591 COc1cccc(/C=C/2\CCCC3=C2OC(=C(C#N)C3c4cccc(OC)c4)N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B10 compound treatment 750568.0 163000.0 0.73 714441.0 153000.0 0.76 1.0522 0.9999 1710241 ChemDiv1_010592 CCOC(=O)c1c(C)n(C)c2cc(CN(C)C)c(O)c(c12)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B11 compound treatment 731715.0 145000.0 0.65 722878.0 161000.0 0.8 1.0221 0.9945 1573474 ChemDiv1_010593 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(CC)cc2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B12 compound treatment 674664.0 87500.0 0.39 684544.0 123000.0 0.61 0.7072 0.9773 1777954 ChemDiv1_010594 COc1cc(cc([N+](=O)[O-])c1O)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B13 compound treatment 756820.0 170000.0 0.76 731250.0 170000.0 0.84 1.1309 0.9987 1975126 ChemDiv1_010595 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(Cl)c(Cl)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B14 compound treatment 742156.0 155000.0 0.69 723273.0 162000.0 0.8 1.0565 0.9975 1975127 ChemDiv1_010596 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc5ccccc45)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B15 compound treatment 754536.0 167000.0 0.75 749030.0 187000.0 0.93 1.1859 0.9944 1555216 ChemDiv1_010597 Cc1c(Nc2nc3nonc3nc2Nc4ccc(C)c(C)c4)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B16 compound treatment 738633.0 151000.0 0.68 714177.0 152000.0 0.76 1.0135 0.9985 1975128 ChemDiv1_010598 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)c4ccc(cc4)C(=O)Nc5cccc6C(=O)c7ccccc7C(=O)c56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B17 compound treatment 753964.0 167000.0 0.75 716601.0 155000.0 0.77 1.0705 0.9999 1975129 ChemDiv1_010599 COC(=O)CN1C(=N)N(CC1=O)c2nc(nc(n2)N(C)C)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B18 compound treatment 737894.0 151000.0 0.67 694608.0 133000.0 0.66 0.9426 0.9999 1205571 ChemDiv1_010600 COC(=O)CN1C(=O)C2(OCCCO2)c3cc(C)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B19 compound treatment 731599.0 144000.0 0.65 714087.0 152000.0 0.75 0.9909 0.997 1975130 ChemDiv1_010601 Nc1nc(SCC(=O)c2ccc(Br)cc2)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B20 compound treatment 711974.0 125000.0 0.56 695930.0 134000.0 0.67 0.8652 0.9962 1975131 ChemDiv1_010602 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccsc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B21 compound treatment 621512.0 34300.0 0.15 617162.0 55500.0 0.27 0.303 0.9623 1975132 ChemDiv1_010603 [O-][N+](=O)c1ccc(cc1)C(=O)NN2C(=O)c3cc(cc4cc(cc(C2=O)c34)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B22 compound treatment 666600.0 79400.0 0.36 641343.0 79700.0 0.39 0.5304 0.9986 1621158 ChemDiv1_010604 CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccc(Br)cc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B23 mock treatment 665043.0 77900.0 0.35 657832.0 96100.0 0.48 0.5832 0.9882 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 B24 mock treatment 525441.0 -61700.0 -0.28 503919.0 -57800.0 -0.29 -0.3978 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C01 compound treatment 615874.0 28700.0 0.13 599678.0 38000.0 0.19 0.2239 0.9826 1975133 ChemDiv1_010605 CCOCCOC(=O)C1=C(C)NC2=C(C1c3cc(OCC)c(O)c(c3)[N+](=O)[O-])C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C02 compound treatment 687892.0 101000.0 0.45 663985.0 102000.0 0.51 0.6771 0.9983 1258342 ChemDiv1_010606 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)c3ccccc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C03 compound treatment 685493.0 98300.0 0.44 693066.0 131000.0 0.65 0.7714 0.9818 1975134 ChemDiv1_010607 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccc(c4)[N+](=O)[O-])C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C04 compound treatment 707712.0 121000.0 0.54 711716.0 150000.0 0.74 0.907 0.9876 1975135 ChemDiv1_010608 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C05 compound treatment 720707.0 134000.0 0.6 746930.0 185000.0 0.92 1.0715 0.9784 1975136 ChemDiv1_010609 CCC(C(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(C)n2)(C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C06 compound treatment 708575.0 121000.0 0.54 704462.0 143000.0 0.71 0.8843 0.9915 1249737 ChemDiv1_010610 COc1ccccc1n2c(CSCC(=O)Nc3ccc4ccccc4c3)nc5ccccc5c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C07 compound treatment 739471.0 152000.0 0.68 751158.0 189000.0 0.94 1.1457 0.9877 1975137 ChemDiv1_010611 CCC1NC(Cc2c1[nH]c3ccccc23)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C08 compound treatment 767336.0 180000.0 0.81 765959.0 204000.0 1.01 1.2857 0.9937 1975138 ChemDiv1_010612 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C(=O)N)OC(=C(C#N)C1c3cccs3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C09 compound treatment 767434.0 180000.0 0.81 741751.0 180000.0 0.89 1.2013 0.9987 1975139 ChemDiv1_010613 CCOC(=O)C1=C(N)Oc2c(C1c3cc(cs3)[N+](=O)[O-])c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C10 compound treatment 773005.0 186000.0 0.83 750317.0 189000.0 0.93 1.2489 0.9983 1975140 ChemDiv1_010614 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(OC)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C11 compound treatment 766423.0 179000.0 0.8 737893.0 176000.0 0.87 1.1845 0.9991 1975141 ChemDiv1_010615 CCOC(=O)C1=C(OC(=C(C#N)C1c2cc3ccccc3nc2Cl)N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C12 compound treatment 726535.0 139000.0 0.62 757629.0 196000.0 0.97 1.1274 0.9771 1975142 ChemDiv1_010616 COCCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C13 compound treatment 732349.0 145000.0 0.65 731754.0 170000.0 0.84 1.0552 0.9918 1975143 ChemDiv1_010617 COc1ccc(NC(=O)CSc2nc(N)nc(SC)c2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C14 compound treatment 769269.0 182000.0 0.82 746416.0 185000.0 0.92 1.2234 0.9983 1393589 ChemDiv1_010618 NC1=C(C#N)C(C(=C(O1)c2ccccc2)C(=O)c3ccccc3)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C15 compound treatment 788636.0 201000.0 0.9 790484.0 229000.0 1.13 1.4391 0.9936 1975144 ChemDiv1_010619 NC(=O)CSc1nc(cc(c1C#N)c2ccccc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C16 compound treatment 806961.0 220000.0 0.98 784577.0 223000.0 1.1 1.4764 0.9983 1601979 ChemDiv1_010620 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(SC)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C17 compound treatment 784781.0 198000.0 0.88 745073.0 183000.0 0.91 1.2678 0.9999 1132613 ChemDiv1_010621 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(Cc4ccccc4)c5cc(Br)c(O)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C18 compound treatment 748960.0 162000.0 0.72 721467.0 160000.0 0.79 1.0717 0.999 1975145 ChemDiv1_010622 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(Cl)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C19 compound treatment 743890.0 157000.0 0.7 737177.0 175000.0 0.87 1.1107 0.9943 1719028 ChemDiv1_010623 CCOC(=O)c1c(C)n(c2ccccc2)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C20 compound treatment 1116833.0 530000.0 2.37 1103094.0 541000.0 2.68 3.5729 0.9981 1359860 ChemDiv1_010624 Nc1c(sc2nc(ccc12)c3ccccn3)C(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C21 compound treatment 765164.0 178000.0 0.8 703578.0 142000.0 0.7 1.0604 0.9981 1975146 ChemDiv1_010625 COc1ccc(Nc2nc(nc(C)c2[N+](=O)[O-])N(C)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C22 compound treatment 714077.0 127000.0 0.57 681036.0 119000.0 0.59 0.8197 0.9998 1975147 ChemDiv1_010626 COc1ccc(Br)cc1C2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C23 mock treatment 716601.0 129000.0 0.58 674560.0 113000.0 0.56 0.805 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 C24 mock treatment 306842.0 -280000.0 -1.25 509980.0 -51700.0 -0.26 -1.0685 -0.8342 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D01 compound treatment 595643.0 8450.0 0.04 588870.0 27200.0 0.13 0.122 0.872 1975148 ChemDiv1_010627 Cc1ccccc1NC(=O)CSc2nc(N)c(C#N)c(c3cccs3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D02 compound treatment 640466.0 53300.0 0.24 617601.0 55900.0 0.28 0.3645 0.9972 1975149 ChemDiv1_010628 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D03 compound treatment 702186.0 115000.0 0.51 689170.0 127000.0 0.63 0.8105 0.9949 1975150 ChemDiv1_010629 COc1ccc(NC(=O)CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D04 compound treatment 699401.0 112000.0 0.5 672136.0 110000.0 0.55 0.7421 0.9991 1975151 ChemDiv1_010630 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])C(F)(F)C(F)(F)C(F)(F)F)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D05 compound treatment 718410.0 131000.0 0.59 724805.0 163000.0 0.81 0.9867 0.9877 1975152 ChemDiv1_010631 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D06 compound treatment 677074.0 89900.0 0.4 648769.0 87100.0 0.43 0.5895 0.9994 1777550 ChemDiv1_010632 CCC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D07 compound treatment 795365.0 208000.0 0.93 741682.0 180000.0 0.89 1.2894 0.9998 1975153 ChemDiv1_010633 CSc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)OC(C)C)CSc3nc(C)c(C)c(C)c3C#N)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D08 compound treatment 741825.0 155000.0 0.69 716096.0 154000.0 0.76 1.0303 0.9988 1975154 ChemDiv1_010634 CC1=NN(C(=O)C1=CNc2ccc(Br)cn2)c3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D09 compound treatment 806650.0 219000.0 0.98 790569.0 229000.0 1.13 1.4964 0.9974 1975155 ChemDiv1_010635 NC1=C(C#N)C(C2=C(O1)/C(=C/c3cccs3)/CN(Cc4ccccc4)C2)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D10 compound treatment 1332134.0 745000.0 3.33 1268220.0 707000.0 3.5 4.8328 0.9997 1975156 ChemDiv1_010636 Clc1ccc(cc1)C(=O)CSc2nc(ccc2C#N)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D11 compound treatment 782598.0 195000.0 0.87 754266.0 193000.0 0.95 1.2931 0.9991 1975157 ChemDiv1_010637 CCOC(=O)C1=C(OC(=C(C#N)C1c2cccnc2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D12 compound treatment 746127.0 159000.0 0.71 728268.0 167000.0 0.83 1.0866 0.9973 1183057 ChemDiv1_010638 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCC(=O)N3CCCCC3)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D13 compound treatment 907117.0 320000.0 1.43 913109.0 351000.0 1.74 2.2436 0.9953 1975158 ChemDiv1_010639 NC1=C(C#N)C(C2=C(O1)/C(=C/c3cccnc3)/CN(Cc4ccccc4)C2)c5cccnc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D14 compound treatment 744596.0 157000.0 0.7 734757.0 173000.0 0.86 1.1045 0.9953 1975159 ChemDiv1_010640 [O-][N+](=O)c1ccc(cc1)N2C(=O)C3C4OC(CNC(=O)COc5ccc(Cl)cc5Cl)(C=C4)C3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D15 compound treatment 805734.0 219000.0 0.98 739738.0 178000.0 0.88 1.3154 0.9987 1778631 ChemDiv1_010641 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2c(C)c([N+](=O)[O-])c(C)c([N+](=O)[O-])c2C)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D16 compound treatment 736019.0 149000.0 0.67 734254.0 173000.0 0.85 1.0756 0.9924 1317911 ChemDiv1_010642 Brc1ccc(cc1S(=O)(=O)N2CCCCC2)C(=O)Nc3ccc(cc3)C(=O)Oc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D17 compound treatment 778318.0 191000.0 0.86 772819.0 211000.0 1.05 1.3445 0.995 1553768 ChemDiv1_010643 CCOC(=O)c1c(C)n(C2CCCCC2)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D18 compound treatment 723262.0 136000.0 0.61 714293.0 153000.0 0.76 0.9653 0.9943 1975160 ChemDiv1_010644 CC(C)CN/C(=C\1/C(=NN(C1=O)c2ccc(Br)cc2Br)C)/C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D19 compound treatment 791769.0 205000.0 0.92 764145.0 202000.0 1.0 1.3567 0.999 1418950 ChemDiv1_010645 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)S(=O)(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D20 compound treatment 764333.0 177000.0 0.79 729695.0 168000.0 0.83 1.1492 0.9997 1738255 ChemDiv1_010646 CCOc1nc(C)cc(COC)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D21 compound treatment 957570.0 370000.0 1.66 969736.0 408000.0 2.02 2.6017 0.9952 1975161 ChemDiv1_010647 NS(=O)(=O)c1ccc(cc1)N2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D22 compound treatment 725100.0 138000.0 0.62 696418.0 135000.0 0.67 0.9085 0.9992 1470395 ChemDiv1_010648 CCOC(=O)C1=C(N)OC2=C(C(=O)CCC2)C31C(=O)Nc4ccc(Br)cc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D23 mock treatment 684588.0 97400.0 0.44 683448.0 122000.0 0.6 0.7348 0.9873 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 D24 mock treatment 532268.0 -54900.0 -0.25 503437.0 -58300.0 -0.29 -0.3779 -0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E01 compound treatment 628377.0 41200.0 0.18 628786.0 67100.0 0.33 0.3654 0.9613 1871284 ChemDiv1_010649 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc5OCOc5c4)C(=O)OCCc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E02 compound treatment 658421.0 71200.0 0.32 672191.0 111000.0 0.55 0.6125 0.9669 1975162 ChemDiv1_010650 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E03 compound treatment 710155.0 123000.0 0.55 694348.0 133000.0 0.66 0.8539 0.9961 1871368 ChemDiv1_010651 COc1ccc(cc1OC)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E04 compound treatment 719750.0 133000.0 0.59 717768.0 156000.0 0.77 0.9663 0.9915 1975163 ChemDiv1_010652 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccccc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E05 compound treatment 742601.0 155000.0 0.7 758755.0 197000.0 0.98 1.1822 0.9862 1874566 ChemDiv1_010653 CC(C)Nc1nc(NC(C)C)nc(Oc2ccc(=O)n(C)n2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E06 compound treatment 855284.0 268000.0 1.2 855996.0 294000.0 1.46 1.8795 0.9953 1975164 ChemDiv1_010654 COC(=O)C1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E07 compound treatment 813177.0 226000.0 1.01 801777.0 240000.0 1.19 1.5563 0.9968 1975165 ChemDiv1_010655 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccc2)c1C#N)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E08 compound treatment 777339.0 190000.0 0.85 765121.0 203000.0 1.01 1.3145 0.9965 1975166 ChemDiv1_010656 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E09 compound treatment 726689.0 139000.0 0.62 763921.0 202000.0 1.0 1.1499 0.9741 1975167 ChemDiv1_010657 CCOC(=O)C1=C(N)OC2=C(C1c3ccsc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E10 compound treatment 946320.0 359000.0 1.61 845687.0 284000.0 1.41 2.1316 0.9978 1975168 ChemDiv1_010658 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4cccs4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E11 compound treatment 829259.0 242000.0 1.08 873526.0 312000.0 1.54 1.8585 0.985 1975169 ChemDiv1_010659 COc1ccc(OC)c(/C=C\2/SC(=S)N(CNc3ccc(Br)cc3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E12 compound treatment 1031165.0 444000.0 1.99 1032368.0 471000.0 2.33 3.054 0.9968 1633191 ChemDiv1_010660 NC1=C(C#N)C2=CCN(Cc3ccccc3)CC2C4(C(=O)Nc5ccccc54)C1(C#N)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E13 compound treatment 748657.0 161000.0 0.72 790225.0 229000.0 1.13 1.3116 0.9765 1975170 ChemDiv1_010661 CSc1nc(N)nc(SCC(=O)Nc2ccccc2[N+](=O)[O-])c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E14 compound treatment 737516.0 150000.0 0.67 745758.0 184000.0 0.91 1.1206 0.9888 1633852 ChemDiv1_010662 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E15 compound treatment 1057930.0 471000.0 2.11 1070429.0 509000.0 2.52 3.2721 0.996 1975171 ChemDiv1_010663 CCc1nnc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E16 compound treatment 766994.0 180000.0 0.8 781925.0 220000.0 1.09 1.3406 0.9888 1549855 ChemDiv1_010664 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E17 compound treatment 793880.0 207000.0 0.93 762388.0 201000.0 0.99 1.3573 0.9994 1975172 ChemDiv1_010665 CC(NC(=O)c1ccc(cc1)C2SCC(=O)N2Cc3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E18 compound treatment 862415.0 275000.0 1.23 822305.0 261000.0 1.29 1.7841 0.9997 1975173 ChemDiv1_010666 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(OCc4ccccc4)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E19 compound treatment 775702.0 189000.0 0.84 737780.0 176000.0 0.87 1.2135 0.9999 1975174 ChemDiv1_010667 COc1cc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccccc4)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E20 compound treatment 763637.0 176000.0 0.79 741654.0 180000.0 0.89 1.1889 0.9982 1104609 ChemDiv1_010668 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(C)cc2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E21 compound treatment 786753.0 200000.0 0.89 740987.0 179000.0 0.89 1.2597 1.0 1591951 ChemDiv1_010669 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E22 compound treatment 738627.0 151000.0 0.68 717672.0 156000.0 0.77 1.0257 0.9979 1975175 ChemDiv1_010670 CC(=O)c1ccc(cc1)N2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E23 mock treatment 721581.0 134000.0 0.6 691605.0 130000.0 0.64 0.8805 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 E24 mock treatment 531933.0 -55300.0 -0.25 407396.0 -154000.0 -0.76 -0.7154 -0.8905 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F01 compound treatment 591230.0 4040.0 0.02 565894.0 4210.0 0.02 0.0275 0.9975 1975176 ChemDiv1_010671 Nc1nc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])c(C#N)c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F02 compound treatment 626541.0 39400.0 0.18 607184.0 45500.0 0.23 0.2839 0.9926 1975177 ChemDiv1_010672 [O-][N+](=O)c1cc2C(=O)N(C(=O)c3cc(cc(c1)c23)[N+](=O)[O-])c4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F03 compound treatment 698859.0 112000.0 0.5 642364.0 80700.0 0.4 0.6361 0.9939 1975178 ChemDiv1_010673 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3F)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F04 compound treatment 697414.0 110000.0 0.49 719025.0 157000.0 0.78 0.9 0.9757 1578292 ChemDiv1_010674 CCOC(=O)c1c(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F05 compound treatment 737628.0 150000.0 0.67 744624.0 183000.0 0.91 1.117 0.9893 1975179 ChemDiv1_010675 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(Cl)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F06 compound treatment 736693.0 150000.0 0.67 699822.0 138000.0 0.68 0.9571 0.9999 1303283 ChemDiv1_010676 CCOC(=O)c1c(CN2CCN(C)CC2)n(C)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F07 compound treatment 752049.0 165000.0 0.74 714886.0 153000.0 0.76 1.0585 0.9999 1975180 ChemDiv1_010677 CCOC(=O)CC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(F)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F08 compound treatment 760088.0 173000.0 0.77 720066.0 158000.0 0.78 1.102 1.0 1975181 ChemDiv1_010678 CC(=O)c1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F09 compound treatment 983688.0 396000.0 1.77 879739.0 318000.0 1.58 2.3691 0.9982 1975182 ChemDiv1_010679 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4cccc(F)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F10 compound treatment 725077.0 138000.0 0.62 718544.0 157000.0 0.78 0.9859 0.9935 1781400 ChemDiv1_010680 [O-][N+](=O)c1ccc(Cl)c(c1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F11 compound treatment 779071.0 192000.0 0.86 753328.0 192000.0 0.95 1.2786 0.9988 1230938 ChemDiv1_010681 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(SC)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F12 compound treatment 761654.0 174000.0 0.78 741711.0 180000.0 0.89 1.1828 0.9978 1400687 ChemDiv1_010682 CCOC(=O)C1=C(N)OC(=C(C(=O)OC(C)(C)C)C21C(=O)Nc3ccccc32)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F13 compound treatment 759370.0 172000.0 0.77 738442.0 177000.0 0.88 1.1641 0.998 1975183 ChemDiv1_010683 COc1cccc(/C=C/2\SC(=O)N(CNc3cccc(Br)c3)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F14 compound treatment 747011.0 160000.0 0.72 723365.0 162000.0 0.8 1.0722 0.9984 1665907 ChemDiv1_010684 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)OCc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F15 compound treatment 792308.0 205000.0 0.92 761919.0 200000.0 0.99 1.3506 0.9993 1604763 ChemDiv1_010685 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(O)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F16 compound treatment 745086.0 158000.0 0.71 718752.0 157000.0 0.78 1.05 0.9989 1975184 ChemDiv1_010686 COc1ccc(cc1/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F17 compound treatment 755759.0 169000.0 0.75 772998.0 211000.0 1.05 1.2738 0.9871 1975185 ChemDiv1_010687 CN(C)c1nc(nc(n1)N2CC(=O)N(CCBr)C2=O)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F18 compound treatment 717609.0 130000.0 0.58 693763.0 132000.0 0.65 0.8754 0.9984 1975186 ChemDiv1_010688 [O-][N+](=O)c1cc(C=C2C(=O)NC(=S)NC2=O)ccc1Sc3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F19 compound treatment 760707.0 174000.0 0.78 732982.0 171000.0 0.85 1.1492 0.999 1692416 ChemDiv1_010689 CCOC(=O)c1c(C)n(C)c2ccc(OC)c(c12)S(=O)(=O)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F20 compound treatment 755292.0 168000.0 0.75 724321.0 163000.0 0.81 1.1018 0.9994 1975187 ChemDiv1_010690 COCc1cc(C)nc(SSc2nc(C)cc(COC)c2C#N)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F21 compound treatment 757593.0 170000.0 0.76 729292.0 168000.0 0.83 1.1265 0.9991 1975188 ChemDiv1_010691 [O-][N+](=O)c1ccc(cc1)C(=O)NN2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F22 compound treatment 734908.0 148000.0 0.66 685035.0 123000.0 0.61 0.8996 0.9992 1668589 ChemDiv1_010692 CC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccc(F)cc43)C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F23 mock treatment 698910.0 112000.0 0.5 687025.0 125000.0 0.62 0.7927 0.9942 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 F24 mock treatment 509132.0 -78100.0 -0.35 497271.0 -64400.0 -0.32 -0.4727 -0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G01 compound treatment 619648.0 32500.0 0.15 613364.0 51700.0 0.26 0.2837 0.964 1871263 ChemDiv1_010693 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4ccccc4F)C(=O)CC(C3)c5cccs5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G02 compound treatment 683414.0 96200.0 0.43 673585.0 112000.0 0.55 0.6965 0.9922 1975189 ChemDiv1_010694 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G03 compound treatment 729369.0 142000.0 0.64 640398.0 78700.0 0.39 0.7257 0.9723 1871299 ChemDiv1_010695 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4ccc5OCOc5c4)C(=O)CC(C3)c6cccs6)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G04 compound treatment 716372.0 129000.0 0.58 718137.0 156000.0 0.78 0.9569 0.9896 1975190 ChemDiv1_010696 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G05 compound treatment 743753.0 157000.0 0.7 738566.0 177000.0 0.88 1.1151 0.9939 1975191 ChemDiv1_010697 CN(C)c1nc(Oc2ccc(OCCOc3ccc(C)cc3)nn2)nc(n1)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G06 compound treatment 888816.0 302000.0 1.35 881290.0 320000.0 1.58 2.0742 0.9969 1975192 ChemDiv1_010698 Cc1cc(c2c(N)c(sc2n1)C(=O)Nc3cccc4ccccc34)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G07 compound treatment 734327.0 147000.0 0.66 756559.0 195000.0 0.97 1.1483 0.9826 1486014 ChemDiv1_010699 O=C(CSc1nc2CCCc2cc1C#N)C3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G08 compound treatment 786163.0 199000.0 0.89 739449.0 178000.0 0.88 1.2525 1.0 1975193 ChemDiv1_010700 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G09 compound treatment 765588.0 178000.0 0.8 685678.0 124000.0 0.61 0.999 0.9916 1348803 ChemDiv1_010701 CCOC(=O)C1=C(N)OC2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G10 compound treatment 734673.0 147000.0 0.66 736485.0 175000.0 0.87 1.0791 0.991 1975194 ChemDiv1_010702 CCOC(=O)c1cc2c(N)c(sc2nc1N)C(=O)Nc3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G11 compound treatment 764334.0 177000.0 0.79 729761.0 168000.0 0.83 1.1494 0.9997 1975195 ChemDiv1_010703 [O-][N+](=O)c1cc(cc(c1)[N+](=O)[O-])C2=N/C(=C\c3ccccc3Br)/C(=O)O2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G12 compound treatment 762606.0 175000.0 0.79 767000.0 205000.0 1.02 1.2744 0.9918 1975196 ChemDiv1_010704 CCOc1ccc(Br)cc1C2C(=C(N)Oc3cc(C)oc(=O)c23)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G13 compound treatment 733149.0 146000.0 0.65 725929.0 164000.0 0.81 1.0373 0.9941 1975197 ChemDiv1_010705 CSc1nc(N)nc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G14 compound treatment 761991.0 175000.0 0.78 769055.0 207000.0 1.03 1.2797 0.991 1975198 ChemDiv1_010706 CCOC(=O)c1ccc(NCN2C(=O)S/C(=C\c3ccc(cc3)C(=O)OC)/C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G15 compound treatment 787793.0 201000.0 0.9 772460.0 211000.0 1.04 1.3733 0.9972 1975199 ChemDiv1_010707 CSc1nc(N)nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G16 compound treatment 796114.0 209000.0 0.94 786399.0 225000.0 1.11 1.4484 0.9962 1652926 ChemDiv1_010708 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCc3ccccc3)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G17 compound treatment 792147.0 205000.0 0.92 798751.0 237000.0 1.17 1.4791 0.9925 1975200 ChemDiv1_010709 CCOC(=O)CC(=O)CSc1nc(cc(c1C#N)c2ccc(F)cc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G18 compound treatment 789411.0 202000.0 0.91 775271.0 214000.0 1.06 1.3882 0.997 1975201 ChemDiv1_010710 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(OCc4ccccc4)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G19 compound treatment 1060092.0 473000.0 2.12 1021376.0 460000.0 2.28 3.1071 0.9993 1975202 ChemDiv1_010711 COc1ccc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G20 compound treatment 737663.0 150000.0 0.67 746480.0 185000.0 0.92 1.1236 0.9886 1975203 ChemDiv1_010712 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccccc2F)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G21 compound treatment 678961.0 91800.0 0.41 688245.0 127000.0 0.63 0.7338 0.979 1975204 ChemDiv1_010713 CCOC(=O)c1cc(C#N)c(SCC(=O)c2ccc(Br)cc2)nc1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G22 compound treatment 730590.0 143000.0 0.64 698343.0 137000.0 0.68 0.9326 0.9996 1975205 ChemDiv1_010714 CC/1=NN(C(=O)\C1=C\Nc2cc(ccc2Cl)[N+](=O)[O-])c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G23 mock treatment 717993.0 131000.0 0.59 700381.0 139000.0 0.69 0.8998 0.9968 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 G24 mock treatment 388112.0 -199000.0 -0.89 532594.0 -29100.0 -0.14 -0.7321 -0.8109 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H01 compound treatment 624254.0 37100.0 0.17 578097.0 16400.0 0.08 0.1748 0.9461 1975206 ChemDiv1_010715 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H02 compound treatment 695223.0 108000.0 0.48 675983.0 114000.0 0.57 0.7423 0.9969 1975207 ChemDiv1_010716 CC1=C(C(C(=C(N)O1)C#N)c2ccncc2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H03 compound treatment 697102.0 110000.0 0.49 684010.0 122000.0 0.61 0.7764 0.9947 1975208 ChemDiv1_010717 CCCCOc1cccc(NC(=O)CSc2nc(N)nc(SC)c2C#N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H04 compound treatment 702288.0 115000.0 0.52 681036.0 119000.0 0.59 0.7824 0.9976 1918195 ChemDiv1_010718 COc1ccc(cc1)N2C(c3ccc(Cl)cc3)S(=O)(=O)/C(=C/c4ccc(Cl)cc4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H05 compound treatment 752460.0 165000.0 0.74 746543.0 185000.0 0.92 1.1706 0.9944 1975209 ChemDiv1_010719 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(F)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H06 compound treatment 683008.0 95800.0 0.43 654685.0 93000.0 0.46 0.629 0.9994 1282583 ChemDiv1_010720 CCOC(=O)c1c(CN2CCN(C)CC2)n(c3ccccc3)c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H07 compound treatment 806927.0 220000.0 0.98 755410.0 194000.0 0.96 1.3741 0.9999 1975210 ChemDiv1_010721 CCOC(=O)C1=C(CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)OC(=C(C#N)C1c4ccccc4Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H08 compound treatment 749582.0 162000.0 0.73 686942.0 125000.0 0.62 0.9528 0.9969 1975211 ChemDiv1_010722 CC1=NN(C(=O)C1=CNc2ccccc2Cl)c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H09 compound treatment 1284118.0 697000.0 3.12 1025773.0 464000.0 2.3 3.8316 0.9887 1975212 ChemDiv1_010723 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccc(Cl)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H10 compound treatment 759693.0 173000.0 0.77 736271.0 175000.0 0.86 1.1576 0.9984 1975213 ChemDiv1_010724 COc1ccc(CCNC(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H11 compound treatment 773823.0 187000.0 0.84 750463.0 189000.0 0.94 1.252 0.9984 1975214 ChemDiv1_010725 CCOC(=O)C1=C(C)OC(=C(C(=O)OCCOC)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H12 compound treatment 763166.0 176000.0 0.79 722315.0 161000.0 0.8 1.1197 1.0 1736783 ChemDiv1_010726 CCC(=O)C1=C(C)OC(=C(C(=O)OC)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H13 compound treatment 758356.0 171000.0 0.77 750796.0 189000.0 0.94 1.2042 0.995 1975215 ChemDiv1_010727 Cc1ccc(/C=C/2\SC(=O)N(CNc3c(C)cc(Br)cc3C)C2=O)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H14 compound treatment 738763.0 152000.0 0.68 735760.0 174000.0 0.86 1.0895 0.993 1648759 ChemDiv1_010728 Nc1ccc2nc(SCC(=O)Nc3ccc4c(c3)oc5ccccc54)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H15 compound treatment 867050.0 280000.0 1.25 816777.0 255000.0 1.26 1.7794 1.0 1975216 ChemDiv1_010729 Cc1cc(nc(SCC(=O)Nc2ccccc2)c1C#N)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H16 compound treatment 769085.0 182000.0 0.81 719261.0 158000.0 0.78 1.1277 0.9998 1975217 ChemDiv1_010730 CCOC(=O)c1c(CNCCN(CC)CC)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H17 compound treatment 766081.0 179000.0 0.8 740481.0 179000.0 0.89 1.1925 0.9987 1329889 ChemDiv1_010731 COc1nc(nc(n1)N(CCOc2ccccc2)C#N)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H18 compound treatment 724588.0 137000.0 0.62 699538.0 138000.0 0.68 0.9178 0.9986 1975218 ChemDiv1_010732 Cc1c(NC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H19 compound treatment 758958.0 172000.0 0.77 735889.0 174000.0 0.86 1.1539 0.9983 1726677 ChemDiv1_010733 CCOC(=O)c1c(CSc2ccccc2)n(Cc3ccccc3)c4ccc(O)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H20 compound treatment 730248.0 143000.0 0.64 682979.0 121000.0 0.6 0.8777 0.9995 1975219 ChemDiv1_010734 CC(C)CCC1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H21 compound treatment 776669.0 189000.0 0.85 756518.0 195000.0 0.97 1.2822 0.9979 1975220 ChemDiv1_010735 [O-][N+](=O)c1cccc(c1)C(=O)NN2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H22 compound treatment 728137.0 141000.0 0.63 707199.0 146000.0 0.72 0.9558 0.9978 1135033 ChemDiv1_010736 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccc(Cl)cc32)C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H23 mock treatment 708940.0 122000.0 0.54 658583.0 96900.0 0.48 0.7248 0.998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 H24 mock treatment 506222.0 -81000.0 -0.36 494560.0 -67100.0 -0.33 -0.4914 -0.9991 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I01 compound treatment 570823.0 -16400.0 -0.07 558546.0 -3140.0 -0.02 -0.0628 -0.8386 1871319 ChemDiv1_010737 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I02 compound treatment 671121.0 83900.0 0.38 665832.0 104000.0 0.52 0.6305 0.9879 1975221 ChemDiv1_010738 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(Cl)c(Cl)c2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I03 compound treatment 708440.0 121000.0 0.54 708658.0 147000.0 0.73 0.8986 0.9895 1975222 ChemDiv1_010739 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4cccs4)C(=O)OCCOc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I04 compound treatment 692444.0 105000.0 0.47 695484.0 134000.0 0.66 0.8018 0.986 1185389 ChemDiv1_010740 COc1cc(ccc1OC(=O)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I05 compound treatment 720174.0 133000.0 0.6 732804.0 171000.0 0.85 1.0203 0.985 1975223 ChemDiv1_010741 C[N+](C)(CCN1C(=O)C2C(C(C=CC2c3ccccc3)c4ccccc4)C1=O)CC(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I06 compound treatment 702631.0 115000.0 0.52 731360.0 170000.0 0.84 0.9597 0.9727 1187832 ChemDiv1_010742 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I07 compound treatment 741448.0 154000.0 0.69 700117.0 138000.0 0.69 0.9732 1.0 1975224 ChemDiv1_010743 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccc4OCOc4c3Br)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I08 compound treatment 803814.0 217000.0 0.97 796771.0 235000.0 1.16 1.5091 0.9959 1975225 ChemDiv1_010744 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccccc3OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I09 compound treatment 731793.0 145000.0 0.65 739239.0 178000.0 0.88 1.0796 0.9886 1212011 ChemDiv1_010745 CCOc1nc(Nc2nc(cs2)c3ccccc3)nc(OCC)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I10 compound treatment 799385.0 212000.0 0.95 784029.0 222000.0 1.1 1.4505 0.9973 1311882 ChemDiv1_010746 CC(C)(C)C(=O)CSc1nc2CCCc2c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I11 compound treatment 772973.0 186000.0 0.83 744034.0 182000.0 0.9 1.2268 0.9991 1975226 ChemDiv1_010747 CCOC(=O)c1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I12 compound treatment 710773.0 124000.0 0.55 771509.0 210000.0 1.04 1.1261 0.9564 1909173 ChemDiv1_010748 CC(=O)c1cc(C#N)c(SCc2ccc(Cl)c(Cl)c2)nc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I13 compound treatment 753999.0 167000.0 0.75 747526.0 186000.0 0.92 1.179 0.9946 1975227 ChemDiv1_010749 FC(F)(F)c1cc(nc(SCC(=O)NCc2ccccc2)c1C#N)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I14 compound treatment 741933.0 155000.0 0.69 732593.0 171000.0 0.85 1.0885 0.995 1234821 ChemDiv1_010750 CC(C)OC(=O)C1=C(N)OC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I15 compound treatment 773774.0 187000.0 0.84 790407.0 229000.0 1.13 1.3918 0.9887 1975228 ChemDiv1_010751 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3cccc(c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I16 compound treatment 771206.0 184000.0 0.82 774618.0 213000.0 1.05 1.3283 0.9925 1262708 ChemDiv1_010752 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OCC=C)cc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I17 compound treatment 910739.0 324000.0 1.45 945401.0 384000.0 1.9 2.3682 0.991 1975229 ChemDiv1_010753 Cc1cc(c2c(N)c(sc2n1)C(=O)Nc3cccc(c3)C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I18 compound treatment 735420.0 148000.0 0.66 761780.0 200000.0 0.99 1.1701 0.981 1975230 ChemDiv1_010754 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccs3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I19 compound treatment 748420.0 161000.0 0.72 727605.0 166000.0 0.82 1.0915 0.9979 1975231 ChemDiv1_010755 [O-][N+](=O)c1ccc2c(CSc3nc4ccc(cc4s3)[N+](=O)[O-])c[nH]c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I20 compound treatment 766610.0 179000.0 0.8 750949.0 189000.0 0.94 1.2309 0.997 1975232 ChemDiv1_010756 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I21 compound treatment 749920.0 163000.0 0.73 742630.0 181000.0 0.9 1.1489 0.9947 1975233 ChemDiv1_010757 O=C(Nc1ccc2C(=O)c3ccccc3C(=O)c2c1)c4cccc(c4)C(=O)Nc5ccc6C(=O)c7ccccc7C(=O)c6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I22 compound treatment 730978.0 144000.0 0.64 699675.0 138000.0 0.68 0.9385 0.9995 1975234 ChemDiv1_010758 [O-][N+](=O)c1cccc(c1)N2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I23 mock treatment 703117.0 116000.0 0.52 696543.0 135000.0 0.67 0.8393 0.9922 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 I24 mock treatment 537373.0 -49800.0 -0.22 286166.0 -276000.0 -1.36 -1.1228 -0.8119 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J01 compound treatment 641774.0 54600.0 0.24 610655.0 49000.0 0.24 0.3443 1.0 1661243 ChemDiv1_010759 CN1CCc2nc(SCC(=O)OCc3ccccc3)c(C#N)c(c4ccccc4)c2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J02 compound treatment 676414.0 89200.0 0.4 659100.0 97400.0 0.48 0.6236 0.9956 1182535 ChemDiv1_010760 Nc1nc(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c(C#N)c(c5cccs5)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J03 compound treatment 719831.0 133000.0 0.59 676102.0 114000.0 0.57 0.8206 0.9997 1975235 ChemDiv1_010761 COCCOC(=O)C1=C(N)OC2=C(C1c3ccccc3Cl)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J04 compound treatment 724860.0 138000.0 0.62 691204.0 130000.0 0.64 0.8894 0.9998 1975236 ChemDiv1_010762 COC(=O)c1ccc(NCN2C(=O)/C(=C\c3cc(OC)c(OC)c(OC)c3)/SC2=S)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J05 compound treatment 739658.0 152000.0 0.68 699954.0 138000.0 0.68 0.9669 1.0 1975237 ChemDiv1_010763 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J06 compound treatment 730298.0 143000.0 0.64 688664.0 127000.0 0.63 0.8978 1.0 1776066 ChemDiv1_010764 Oc1c(C=c2sc3nc4ccccc4n3c2=O)cc(Br)cc1[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J07 compound treatment 789036.0 202000.0 0.9 764866.0 203000.0 1.01 1.3506 0.9986 1975238 ChemDiv1_010765 COc1ccc(NC(=O)CSc2nc(ccc2C#N)c3cccs3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J08 compound treatment 734988.0 148000.0 0.66 702093.0 140000.0 0.7 0.9596 0.9997 1975239 ChemDiv1_010766 CC1=NN(C(=O)C1=CNc2ccc(Cl)cc2Cl)c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J09 compound treatment 798255.0 211000.0 0.94 735138.0 173000.0 0.86 1.2756 0.9989 1578894 ChemDiv1_010767 CCOC(=O)C1=C(CSc2nc(N)c(C#N)c(c3cccs3)c2C#N)OC(=C(C#N)C1c4ccccc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J10 compound treatment 746508.0 159000.0 0.71 714569.0 153000.0 0.76 1.0398 0.9995 1724961 ChemDiv1_010768 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccc5OCOc5c4)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J11 compound treatment 773265.0 186000.0 0.83 744475.0 183000.0 0.91 1.2293 0.9991 1975240 ChemDiv1_010769 CC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J12 compound treatment 765115.0 178000.0 0.8 716643.0 155000.0 0.77 1.106 0.9998 1147389 ChemDiv1_010770 CCOC(=O)C1=C(C)OC(=C(C(=O)OC(C)(C)C)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J13 compound treatment 732620.0 145000.0 0.65 697974.0 136000.0 0.68 0.9377 0.9998 1975241 ChemDiv1_010771 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(Cl)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J14 compound treatment 776719.0 190000.0 0.85 738770.0 177000.0 0.88 1.2202 0.9999 1380438 ChemDiv1_010772 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J15 compound treatment 786348.0 199000.0 0.89 777478.0 216000.0 1.07 1.3863 0.9959 1975242 ChemDiv1_010773 COc1ccc(C2=NN(C(C2)c3ccc(C)o3)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J16 compound treatment 758361.0 171000.0 0.77 736125.0 174000.0 0.86 1.1528 0.9982 1975243 ChemDiv1_010774 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(Cl)c2Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J17 compound treatment 775739.0 189000.0 0.84 719079.0 157000.0 0.78 1.1481 0.9992 1776173 ChemDiv1_010775 Cc1c(Br)c(nn1CC(=O)Nc2cc(Oc3cccnc3)cc(c2)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J18 compound treatment 750124.0 163000.0 0.73 719739.0 158000.0 0.78 1.0694 0.9994 1566248 ChemDiv1_010776 ONC(=O)CN1C(=O)C2(OCCO2)c3cc(Br)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J19 compound treatment 766063.0 179000.0 0.8 723035.0 161000.0 0.8 1.1314 1.0 1975244 ChemDiv1_010777 Cc1nn(c(Cl)c1/C=C/2\N=C(OC2=O)c3ccc(C)c(c3)[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J20 compound treatment 768015.0 181000.0 0.81 707515.0 146000.0 0.72 1.0832 0.9984 1975245 ChemDiv1_010778 [O-][N+](=O)c1ccc(CSc2nc3C4CCN(CC4)c3cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J21 compound treatment 762925.0 176000.0 0.79 723615.0 162000.0 0.8 1.1235 1.0 1975246 ChemDiv1_010779 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)c3ccc(N)cc3)c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J22 compound treatment 734410.0 147000.0 0.66 692042.0 130000.0 0.65 0.9226 0.9999 1975247 ChemDiv1_010780 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(F)cc43)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J23 mock treatment 724708.0 138000.0 0.62 669635.0 108000.0 0.53 0.8134 0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 J24 mock treatment 511341.0 -75800.0 -0.34 500621.0 -61100.0 -0.3 -0.454 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K01 compound treatment 592948.0 5760.0 0.03 598332.0 36600.0 0.18 0.1466 0.7995 1975248 ChemDiv1_010781 CCSCCOC(=O)C1=C(C)NC2=C(C1c3ccc(OC(=O)C)cc3)C(=O)CC(C2)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K02 compound treatment 665281.0 78100.0 0.35 648228.0 86500.0 0.43 0.5503 0.9949 1129907 ChemDiv1_010782 NC1=C(C#N)C(c2cc(Br)ccc2F)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K03 compound treatment 677088.0 89900.0 0.4 673510.0 112000.0 0.55 0.6762 0.9877 1871222 ChemDiv1_010783 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K04 compound treatment 717619.0 130000.0 0.58 697577.0 136000.0 0.67 0.8888 0.9975 1975249 ChemDiv1_010784 [O-][N+](=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccc(cc3)C(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K05 compound treatment 649245.0 62100.0 0.28 712184.0 150000.0 0.75 0.7236 0.9095 1591516 ChemDiv1_010785 CCOC(=O)c1sc2nc(N3CCOCC3)c4CN(C)CCc4c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K06 compound treatment 703548.0 116000.0 0.52 680109.0 118000.0 0.59 0.7831 0.9982 1975250 ChemDiv1_010786 CCOC(=O)c1c(CBr)n(CCBr)c2cc(Br)c(OC)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K07 compound treatment 1561663.0 974000.0 4.36 1594199.0 1030000.0 5.11 6.7012 0.9969 1975251 ChemDiv1_010787 FC(F)(F)c1cc(nc(SCC(=O)C2CC2)c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K08 compound treatment 804169.0 217000.0 0.97 781091.0 219000.0 1.09 1.4553 0.9984 1975252 ChemDiv1_010788 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccc(OC)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K09 compound treatment 756459.0 169000.0 0.76 753005.0 191000.0 0.95 1.2059 0.9938 1934900 ChemDiv1_010789 OC1(CC(=NN1C(=O)c2cccc(Br)c2)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K10 compound treatment 724544.0 137000.0 0.61 743580.0 182000.0 0.9 1.0719 0.9826 1975253 ChemDiv1_010790 CC(C)(C)OC(=O)CSc1nc2CCCc2c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K11 compound treatment 751673.0 164000.0 0.74 742316.0 181000.0 0.89 1.1533 0.9953 1494447 ChemDiv1_010791 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Cl)c(O)c(Cl)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K12 compound treatment 731970.0 145000.0 0.65 694093.0 132000.0 0.66 0.9221 1.0 1975254 ChemDiv1_010792 COCCOC(=O)C1=C(N)OC2=C(C1c3ccc(Br)cc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K13 compound treatment 763427.0 176000.0 0.79 773531.0 212000.0 1.05 1.2999 0.9901 1975255 ChemDiv1_010793 [O-][N+](=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K14 compound treatment 762292.0 175000.0 0.78 726109.0 164000.0 0.81 1.1302 0.9998 1730692 ChemDiv1_010794 NC1=C(C#N)C(c2ccc(OCc3ccccc3)cc2)c4c(O1)c5ccccc5oc4=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K15 compound treatment 747660.0 160000.0 0.72 759549.0 198000.0 0.98 1.201 0.9883 1975256 ChemDiv1_010795 NC1=C(C#N)C(c2ccc(F)c(Br)c2)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K16 compound treatment 729044.0 142000.0 0.63 731521.0 170000.0 0.84 1.0439 0.9904 1975257 ChemDiv1_010796 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K17 compound treatment 742350.0 155000.0 0.69 743030.0 181000.0 0.9 1.1263 0.9919 1925625 ChemDiv1_010797 Brc1cccc(c1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K18 compound treatment 766361.0 179000.0 0.8 725640.0 164000.0 0.81 1.1414 1.0 1975258 ChemDiv1_010798 CCOC(=O)C1=C(CSc2nc3CCCc3cc2C#N)OC(=C(C#N)C1c4cccs4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K19 compound treatment 746000.0 159000.0 0.71 729866.0 168000.0 0.83 1.0918 0.9969 1720450 ChemDiv1_010799 Cc1cccc(c1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K20 compound treatment 757576.0 170000.0 0.76 635681.0 74000.0 0.37 0.7985 0.9436 1975259 ChemDiv1_010800 CC1=C(C(C(=C(N)O1)C#N)c2cccs2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K21 compound treatment 730175.0 143000.0 0.64 710443.0 149000.0 0.74 0.9737 0.9975 1975260 ChemDiv1_010801 COC(=O)c1ccc(/C=C\2/SC(=O)N(CNc3ccc(OC)cc3OC)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K22 compound treatment 723924.0 137000.0 0.61 675014.0 113000.0 0.56 0.8298 0.9991 1711890 ChemDiv1_010802 O=c1[nH]n(c2ncnc3sc4CCCCc4c23)c(=O)c5cccc6cccc1c65 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K23 mock treatment 701257.0 114000.0 0.51 665207.0 104000.0 0.51 0.7237 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 K24 mock treatment 517799.0 -69400.0 -0.31 504777.0 -56900.0 -0.28 -0.419 -0.9988 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L01 compound treatment 618551.0 31400.0 0.14 599481.0 37800.0 0.19 0.2316 0.9899 1975261 ChemDiv1_010803 Nc1nc(SCC(=O)NCc2ccccc2)c(C#N)c(c1C#N)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L02 compound treatment 688713.0 102000.0 0.45 673562.0 112000.0 0.55 0.7132 0.9951 1975262 ChemDiv1_010804 COc1ccc(cc1)N(C)CN2C(=O)/C(=C\c3cccc(F)c3)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L03 compound treatment 730021.0 143000.0 0.64 679181.0 117000.0 0.58 0.8637 0.9989 1651380 ChemDiv1_010805 CC(C)OC(=O)C1=C(N)OC2=C(C1c3ccccc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L04 compound treatment 698798.0 112000.0 0.5 678450.0 117000.0 0.58 0.7623 0.9973 1975263 ChemDiv1_010806 CCCCOc1cccc(NC(=O)CSc2nc(C)cc(c2C#N)c3cccnc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L05 compound treatment 755588.0 168000.0 0.75 690023.0 128000.0 0.64 0.9826 0.9964 1975264 ChemDiv1_010807 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3Br)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L06 compound treatment 706474.0 119000.0 0.53 703409.0 142000.0 0.7 0.874 0.9909 1975265 ChemDiv1_010808 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L07 compound treatment 714367.0 127000.0 0.57 652741.0 91100.0 0.45 0.7215 0.9934 1975266 ChemDiv1_010809 CC(C)OC(=O)CC(=O)CSc1nc2CCCCc2c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L08 compound treatment 712805.0 126000.0 0.56 720502.0 159000.0 0.79 0.9539 0.9864 1975267 ChemDiv1_010810 CCOc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L09 compound treatment 1155352.0 568000.0 2.54 1083304.0 522000.0 2.58 3.6255 1.0 1191563 ChemDiv1_010811 CN1CCc2nc(SCC(=O)OC(C)(C)C)c(C#N)c(c3cccs3)c2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L10 compound treatment 732665.0 145000.0 0.65 711386.0 150000.0 0.74 0.9848 0.9979 1508594 ChemDiv1_010812 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OCC(=O)N3CCOCC3)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L11 compound treatment 769355.0 182000.0 0.82 710925.0 149000.0 0.74 1.0994 0.9988 1217290 ChemDiv1_010813 COC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L12 compound treatment 762599.0 175000.0 0.79 710820.0 149000.0 0.74 1.0776 0.9995 1664772 ChemDiv1_010814 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Cl)cc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L13 compound treatment 732315.0 145000.0 0.65 705482.0 144000.0 0.71 0.963 0.9989 1869163 ChemDiv1_010815 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(cc4)[N+](=O)[O-])C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L14 compound treatment 752717.0 166000.0 0.74 665593.0 104000.0 0.51 0.8879 0.9842 1578459 ChemDiv1_010816 Cc1c(NC(=O)CN(c2cc(C)ccc2C)S(=O)(=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L15 compound treatment 755416.0 168000.0 0.75 730039.0 168000.0 0.83 1.1222 0.9987 1975268 ChemDiv1_010817 CCOc1ccc2ccccc2c1/C=C/3\N=C(OC3=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L16 compound treatment 801350.0 214000.0 0.96 748193.0 187000.0 0.92 1.3312 0.9998 1975269 ChemDiv1_010818 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccc(F)c(Br)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L17 compound treatment 805559.0 218000.0 0.98 768969.0 207000.0 1.03 1.4173 0.9997 1204814 ChemDiv1_010819 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(OC(=O)C)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L18 compound treatment 720825.0 134000.0 0.6 709847.0 148000.0 0.73 0.942 0.9948 1545268 ChemDiv1_010820 Cc1ccc2N(CC(=O)O)C(=O)C3(OCCCO3)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L19 compound treatment 754329.0 167000.0 0.75 753140.0 191000.0 0.95 1.1997 0.9931 1975270 ChemDiv1_010821 CCOC(=O)CCCCC(=O)c1[nH]c(=O)[nH]c1CSc2nc(N)c(C#N)cc2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L20 compound treatment 756927.0 170000.0 0.76 692842.0 131000.0 0.65 0.9967 0.997 1486404 ChemDiv1_010822 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Br)cc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L21 compound treatment 728231.0 141000.0 0.63 689766.0 128000.0 0.63 0.8951 1.0 1975271 ChemDiv1_010823 CC/1=NN(C(=O)\C1=C\Nc2cc(cc([N+](=O)[O-])c2O)[N+](=O)[O-])c3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L22 compound treatment 723316.0 136000.0 0.61 687235.0 126000.0 0.62 0.8706 0.9999 1975272 ChemDiv1_010824 COCCOC(=O)C1=C(N)OC(=C(C(=O)C)C21C(=O)Nc3ccccc32)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L23 mock treatment 717576.0 130000.0 0.58 677127.0 115000.0 0.57 0.8171 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 L24 mock treatment 523520.0 -63700.0 -0.29 507709.0 -54000.0 -0.27 -0.3906 -0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M01 compound treatment 618456.0 31300.0 0.14 586115.0 24400.0 0.12 0.1845 0.9974 1975273 ChemDiv1_010825 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc5OCOc5c4)C(=O)OCCOc6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M02 compound treatment 663136.0 75900.0 0.34 610033.0 48300.0 0.24 0.4097 0.9853 1128556 ChemDiv1_010826 COC(=O)c1sc2nc(cc(c3ccc(F)cc3)c2c1N)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M03 compound treatment 707837.0 121000.0 0.54 679673.0 118000.0 0.58 0.7952 0.9992 1871420 ChemDiv1_010827 CC1=C(C(C2=C(CC(CC2=O)c3cccs3)N1)c4ccc(C)c(c4)[N+](=O)[O-])C(=O)OC5CCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M04 compound treatment 722969.0 136000.0 0.61 693948.0 132000.0 0.66 0.8931 0.9993 1172840 ChemDiv1_010828 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M05 compound treatment 670542.0 83400.0 0.37 716500.0 155000.0 0.77 0.8061 0.9452 1975274 ChemDiv1_010829 Cc1nc(NC(=O)(=O)c2ccc(C)cc2)sc1NC(=O)OCCNC(=O)COc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M06 compound treatment 711554.0 124000.0 0.56 654792.0 93100.0 0.46 0.7198 0.9956 1975275 ChemDiv1_010830 CCCCOc1cccc(NC(=O)CSc2nc(C)cc(C)c2C#N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M07 compound treatment 723740.0 137000.0 0.61 660033.0 98300.0 0.49 0.7767 0.9937 1975276 ChemDiv1_010831 COCc1cc(C)nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M08 compound treatment 828440.0 241000.0 1.08 796008.0 234000.0 1.16 1.5844 0.9993 1334338 ChemDiv1_010832 CCOC(=O)C1=C(CSc2nc3CCCc3cc2C#N)OC(=C(C#N)C1c4cccc(OCc5ccccc5)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M09 compound treatment 790167.0 203000.0 0.91 766549.0 205000.0 1.01 1.3601 0.9985 1975277 ChemDiv1_010833 CCOC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(c1C#N)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M10 compound treatment 758022.0 171000.0 0.76 749478.0 188000.0 0.93 1.1985 0.9953 1554542 ChemDiv1_010834 CC1CC=C2C(C1)C3(C(=O)Nc4ccccc43)C(C#N)(C#N)C(=C2C#N)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M11 compound treatment 772225.0 185000.0 0.83 733763.0 172000.0 0.85 1.1884 0.9999 1975278 ChemDiv1_010835 COc1ccc(cc1)c2cc(nc(SCC(=O)O)c2C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M12 compound treatment 939582.0 352000.0 1.58 825513.0 264000.0 1.31 2.0396 0.9956 1975279 ChemDiv1_010836 NC1=C(C#N)C(C2=C(O1)/C(=C/c3ccsc3)/CN(Cc4ccccc4)C2)c5ccsc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M13 compound treatment 741186.0 154000.0 0.69 701038.0 139000.0 0.69 0.9756 1.0 1975280 ChemDiv1_010837 NC(=O)c1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M14 compound treatment 754289.0 167000.0 0.75 738514.0 177000.0 0.88 1.1483 0.9969 1975281 ChemDiv1_010838 CSc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)C)C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M15 compound treatment 686624.0 99400.0 0.45 691997.0 130000.0 0.65 0.7712 0.9835 1320307 ChemDiv1_010839 CCOC(=O)C(C)Sc1nc2CCCCc2c(c3cccs3)c1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M16 compound treatment 708804.0 122000.0 0.54 708481.0 147000.0 0.73 0.8991 0.9898 1975282 ChemDiv1_010840 CC(=O)Nc1cccc(NC(=O)CSc2nc(C)c(C)c(C)c2C#N)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M17 compound treatment 744062.0 157000.0 0.7 707837.0 146000.0 0.72 1.0085 0.9999 1975283 ChemDiv1_010841 Cc1ccc2nc3[nH]c4ccccc4c3nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M18 compound treatment 748791.0 162000.0 0.72 721720.0 160000.0 0.79 1.0721 0.999 1975284 ChemDiv1_010842 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3cccs3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M19 compound treatment 900253.0 313000.0 1.4 894875.0 333000.0 1.65 2.158 0.9967 1975285 ChemDiv1_010843 Cc1cc(c(C#N)c(SCC(=O)NCCc2ccccc2)n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M20 compound treatment 759717.0 173000.0 0.77 711203.0 150000.0 0.74 1.0698 0.9998 1975286 ChemDiv1_010844 CC1=C(C(C(=C(N)O1)C#N)c2ccc(Cl)cc2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M21 compound treatment 697838.0 111000.0 0.5 700198.0 139000.0 0.69 0.8354 0.9872 1975287 ChemDiv1_010845 COCc1cc(C)c(C#N)c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M22 compound treatment 695539.0 108000.0 0.49 660756.0 99100.0 0.49 0.69 1.0 1776560 ChemDiv1_010846 [O-][N+](=O)c1cc2C(=O)N(C(=O)c3cc(cc(c1)c23)[N+](=O)[O-])c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M23 mock treatment 669584.0 82400.0 0.37 667107.0 105000.0 0.52 0.6301 0.9855 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 M24 mock treatment 544921.0 -42300.0 -0.19 385411.0 -176000.0 -0.87 -0.7513 -0.8408 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N01 compound treatment 607544.0 20400.0 0.09 594139.0 32500.0 0.16 0.1781 0.9638 1975288 ChemDiv1_010847 Cc1cccc(NC(=O)CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N02 compound treatment 664388.0 77200.0 0.35 636221.0 74500.0 0.37 0.5054 0.9995 1312702 ChemDiv1_010848 Nc1nc(SCC(=O)c2cc3ccccc3oc2=O)c(C#N)c(c1C#N)c4cccc(O)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N03 compound treatment 1077121.0 490000.0 2.19 1038660.0 477000.0 2.36 3.2215 0.9993 1975289 ChemDiv1_010849 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccc(C#N)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N04 compound treatment 696403.0 109000.0 0.49 656686.0 95000.0 0.47 0.6784 0.9998 1975290 ChemDiv1_010850 COc1cc(/C=C\2/SC(=O)N(CNc3ccccc3C)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N05 compound treatment 738062.0 151000.0 0.68 685941.0 124000.0 0.62 0.9128 0.9989 1975291 ChemDiv1_010851 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3ccccc3I)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N06 compound treatment 704740.0 118000.0 0.53 666839.0 105000.0 0.52 0.7404 1.0 1975292 ChemDiv1_010852 CC(=O)Nc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N07 compound treatment 746306.0 159000.0 0.71 680421.0 119000.0 0.59 0.9195 0.9955 1645343 ChemDiv1_010853 NC1=C(C#N)C2(C(=O)Nc3ccccc32)C(=C(N)S1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N08 compound treatment 716772.0 130000.0 0.58 686219.0 125000.0 0.62 0.8464 0.9995 1975293 ChemDiv1_010854 CC/1=NN(C(=O)\C1=C/Nc2ccc([N+](=O)[O-])c(c2)[N+](=O)[O-])c3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N09 compound treatment 1070549.0 483000.0 2.16 952739.0 391000.0 1.94 2.8998 0.9985 1220507 ChemDiv1_010855 CN1CCc2nc(SCC(=O)OCc3ccccc3)c(C#N)c(c4cccs4)c2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N10 compound treatment 730081.0 143000.0 0.64 685682.0 124000.0 0.61 0.8866 0.9998 1360311 ChemDiv1_010856 CCOC(=O)c1c(CN2CCOCC2)n(C3CCCCC3)c4cc(Br)c(O)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N11 compound treatment 799438.0 212000.0 0.95 742984.0 181000.0 0.9 1.3069 0.9996 1975294 ChemDiv1_010857 CCc1nnc(NC(=O)c2sc3nc(C)cc(c3c2N)C(F)(F)F)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N12 compound treatment 987301.0 400000.0 1.79 966085.0 404000.0 2.0 2.683 0.9984 1975295 ChemDiv1_010858 CCN1C/C(=C\c2ccccc2F)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N13 compound treatment 748385.0 161000.0 0.72 718410.0 157000.0 0.78 1.0592 0.9993 1101575 ChemDiv1_010859 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(c4)[N+](=O)[O-])C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N14 compound treatment 732203.0 145000.0 0.65 647754.0 86100.0 0.43 0.7605 0.9792 1975296 ChemDiv1_010860 COc1ccc(CCNC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N15 compound treatment 758988.0 172000.0 0.77 709278.0 148000.0 0.73 1.0608 0.9997 1975297 ChemDiv1_010861 CCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N16 compound treatment 705890.0 119000.0 0.53 666891.0 105000.0 0.52 0.7442 1.0 1975298 ChemDiv1_010862 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2ccccc2Br)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N17 compound treatment 743964.0 157000.0 0.7 727017.0 165000.0 0.82 1.0754 0.997 1615067 ChemDiv1_010863 CCOC(=O)c1c(C)n(Cc2ccccc2)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N18 compound treatment 645233.0 58000.0 0.26 663059.0 101000.0 0.5 0.5388 0.953 1975299 ChemDiv1_010864 Cc1ccc2NC(=O)C3(NN=C(S3)c4ccccc4O)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N19 compound treatment 855692.0 269000.0 1.2 814399.0 253000.0 1.25 1.7351 0.9998 1975300 ChemDiv1_010865 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c3ccc([N+](=O)[O-])c1c23)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N20 compound treatment 737454.0 150000.0 0.67 708502.0 147000.0 0.73 0.9899 0.9992 1474535 ChemDiv1_010866 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(F)cc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N21 compound treatment 704416.0 117000.0 0.52 685775.0 124000.0 0.61 0.8057 0.9969 1975301 ChemDiv1_010867 Cc1cccc(c1)C(=O)NN2C(=O)c3cccc4c(Br)c(cc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N22 compound treatment 711139.0 124000.0 0.55 672759.0 111000.0 0.55 0.7814 1.0 1406548 ChemDiv1_010868 COC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N23 mock treatment 701186.0 114000.0 0.51 662886.0 101000.0 0.5 0.7153 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 N24 mock treatment 442592.0 -145000.0 -0.65 387641.0 -174000.0 -0.86 -1.0674 -0.99 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O01 compound treatment 591360.0 4170.0 0.02 569629.0 7940.0 0.04 0.041 0.942 1871225 ChemDiv1_010869 COC(=O)c1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCC5CCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O02 compound treatment 627180.0 40000.0 0.18 602678.0 41000.0 0.2 0.2702 0.998 1975302 ChemDiv1_010870 COC(=O)CSc1nc(cc(c1C#N)c2ccc(F)cc2)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O03 compound treatment 649057.0 61900.0 0.28 622663.0 61000.0 0.3 0.4094 0.9991 1975303 ChemDiv1_010871 CCOc1cc(cc([N+](=O)[O-])c1O)C2C(=C(C)NC3=C2C(=O)CC(C3)c4cccs4)C(=O)OCCOC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O04 compound treatment 1193554.0 606000.0 2.71 1006362.0 445000.0 2.2 3.4769 0.9946 1975304 ChemDiv1_010872 Brc1ccc(cc1)C(=O)CSc2nc(ccc2C#N)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O05 compound treatment 700030.0 113000.0 0.51 686268.0 125000.0 0.62 0.7936 0.9951 1975305 ChemDiv1_010873 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(Br)s2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O06 compound treatment 665171.0 78000.0 0.35 660648.0 99000.0 0.49 0.5935 0.9862 1975306 ChemDiv1_010874 CCS(=O)(=O)CCSc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O07 compound treatment 701844.0 115000.0 0.51 615474.0 53800.0 0.27 0.5513 0.9534 1975307 ChemDiv1_010875 COc1ccc([C@H]2C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C#N)c([N+](=O)[O-])c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O08 compound treatment 687045.0 99900.0 0.45 675746.0 114000.0 0.57 0.7156 0.9933 1975308 ChemDiv1_010876 CCOC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(F)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O09 compound treatment 1082950.0 496000.0 2.22 988545.0 427000.0 2.11 3.0644 0.9997 1975309 ChemDiv1_010877 Cc1cc(c(C#N)c(SCC(=O)Nc2ccccc2C)n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O10 compound treatment 680033.0 92800.0 0.42 614842.0 53200.0 0.26 0.4801 0.9758 1678275 ChemDiv1_010878 CCOC(=O)C1=C(N)OC2=C(C(=O)CCC2)C31C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O11 compound treatment 995450.0 408000.0 1.83 947827.0 386000.0 1.91 2.6448 0.9997 1975310 ChemDiv1_010879 COc1ccc(NC(=O)c2sc3nc(C)cc(c3c2N)C(F)(F)F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O12 compound treatment 921323.0 334000.0 1.5 879699.0 318000.0 1.58 2.1716 0.9997 1975311 ChemDiv1_010880 CC(C)N1C/C(=C\c2ccccc2F)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O13 compound treatment 943404.0 356000.0 1.59 855586.0 294000.0 1.46 2.157 0.999 1975312 ChemDiv1_010881 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)NCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O14 compound treatment 757908.0 171000.0 0.76 731001.0 169000.0 0.84 1.1334 0.9989 1975313 ChemDiv1_010882 CC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(OCc3ccccc3)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O15 compound treatment 752541.0 165000.0 0.74 693479.0 132000.0 0.65 0.985 0.998 1188304 ChemDiv1_010883 NC1=C(C#N)C(c2cc(Br)cs2)c3c(O1)c4ccccc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O16 compound treatment 691263.0 104000.0 0.47 652186.0 90500.0 0.45 0.6464 0.9998 1975314 ChemDiv1_010884 Cc1nc(SCC(=O)Nc2ccc(cc2)C(=O)N)c(C#N)c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O17 compound treatment 745534.0 158000.0 0.71 702308.0 141000.0 0.7 0.9938 1.0 1975315 ChemDiv1_010885 CCOC(=O)C1=C(CCl)OC(=C(C#N)C1c2cccc(F)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O18 compound treatment 833386.0 246000.0 1.1 710705.0 149000.0 0.74 1.3013 0.981 1975316 ChemDiv1_010886 CCOC(=O)C1=C(CSc2nc3CCCCCc3cc2C#N)OC(=C(C#N)C1c4ccc(SC)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O19 compound treatment 720782.0 134000.0 0.6 657806.0 96100.0 0.48 0.7595 0.9936 1449111 ChemDiv1_010887 Cc1cccc(C)c1Nc2nc3nonc3nc2Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O20 compound treatment 712842.0 126000.0 0.56 655789.0 94100.0 0.47 0.7273 0.9956 1975317 ChemDiv1_010888 CC1=C(C(C(=C(N)O1)C#N)c2ccsc2)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O21 compound treatment 671957.0 84800.0 0.38 675405.0 114000.0 0.56 0.6666 0.9815 1975318 ChemDiv1_010889 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2Cl)[N+](=O)[O-])c3ccccc3C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O22 compound treatment 672904.0 85700.0 0.38 616307.0 54600.0 0.27 0.4626 0.9854 1975319 ChemDiv1_010890 CC/1=NN(C(=O)\C1=C/Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O23 mock treatment 661001.0 73800.0 0.33 619564.0 57900.0 0.29 0.4364 0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 O24 mock treatment 186429.0 -401000.0 -1.79 413813.0 -148000.0 -0.73 -1.7865 -0.9219 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P01 compound treatment 573500.0 -13700.0 -0.06 554498.0 -7190.0 -0.04 -0.0685 -0.9667 1975320 ChemDiv1_010891 COCCOC(=O)C1=C(N)Oc2c(C1c3ccc(F)cc3)c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P02 compound treatment 598232.0 11000.0 0.05 597802.0 36100.0 0.18 0.1614 0.8699 1975321 ChemDiv1_010892 Cc1ccc(o1)c2cc(C)nc(SCC(=O)c3ccc(Br)cc3)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P03 compound treatment 744199.0 157000.0 0.7 727538.0 166000.0 0.82 1.0779 0.997 1975322 ChemDiv1_010893 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3cccs3)OC(=C(C#N)C1c4ccccc4I)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P04 compound treatment 605789.0 18600.0 0.08 609293.0 47600.0 0.24 0.2256 0.9022 1975323 ChemDiv1_010894 COc1cc(/C=C\2/SC(=O)N(CNc3ccccc3F)C2=O)cc(OC)c1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P05 compound treatment 616799.0 29600.0 0.13 616165.0 54500.0 0.27 0.2845 0.9464 1975324 ChemDiv1_010895 CC(C)OC(=O)C1=C(CSc2nc(C)c(C)c(C)c2C#N)OC(=C(C#N)C1c3cccc(I)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P06 compound treatment 630298.0 43100.0 0.19 602005.0 40300.0 0.2 0.2777 0.9999 1975325 ChemDiv1_010896 CC(=O)Nc1ccc(NC=C2C(=NN(C2=O)c3ccc(C)cc3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P07 compound treatment 802484.0 215000.0 0.96 762129.0 200000.0 0.99 1.3836 0.9999 1975326 ChemDiv1_010897 COc1ccc(/C=C/2\CCCC3=C2OC(=C(C#N)C3c4ccc(OC)cc4)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P08 compound treatment 641040.0 53800.0 0.24 620860.0 59200.0 0.29 0.3777 0.9953 1742371 ChemDiv1_010898 CCOC(=O)c1sc(NC(=O)c2cc3cccc(CC=C)c3oc2=O)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P09 compound treatment 634134.0 46900.0 0.21 625951.0 64300.0 0.32 0.3737 0.9797 1678774 ChemDiv1_010899 CCOC(=O)C1=C(CSc2nc3CCCCc3c(c4cccs4)c2C#N)OC(=C(C#N)C1c5ccc(Cl)cc5)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P10 compound treatment 642243.0 55100.0 0.25 606772.0 45100.0 0.22 0.3322 0.9988 1444877 ChemDiv1_010900 Oc1ccc(cc1)n2c(=O)c3ccc4c(=O)n(c5ccc(O)cc5)c(=O)c6ccc(c2=O)c3c46 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P11 compound treatment 628320.0 41100.0 0.18 614662.0 53000.0 0.26 0.3157 0.985 1975327 ChemDiv1_010901 COCCOC(=O)C1=C(N)OC2=C(C1c3ccncc3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P12 compound treatment 814302.0 227000.0 1.02 780673.0 219000.0 1.08 1.4859 0.9995 1975328 ChemDiv1_010902 CCN1C/C(=C\c2ccc(F)cc2)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P13 compound treatment 646088.0 58900.0 0.26 620433.0 58700.0 0.29 0.3922 0.9988 1322056 ChemDiv1_010903 CC(C)Nc1nc2nonc2nc1Nc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P14 compound treatment 676096.0 88900.0 0.4 623234.0 61500.0 0.3 0.497 0.9913 1975329 ChemDiv1_010904 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(s2)C(C)(C)C)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P15 compound treatment 647254.0 60100.0 0.27 619831.0 58100.0 0.29 0.3938 0.9994 1975330 ChemDiv1_010905 CCOC(=O)CN1C(=N)N(CC1=O)c2nc(nc(n2)N(C)C)N(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P16 compound treatment 653944.0 66800.0 0.3 641756.0 80100.0 0.4 0.4918 0.9903 1455607 ChemDiv1_010906 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)N2CCN(CC2)C(=O)c3cccc(c3)S(=O)(=O)N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P17 compound treatment 640674.0 53500.0 0.24 638461.0 76800.0 0.38 0.4382 0.9751 1495566 ChemDiv1_010907 CCOC(=O)c1c(CSc2ccc(C)cc2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P18 compound treatment 657138.0 69900.0 0.31 621937.0 60200.0 0.3 0.4324 0.9997 1975331 ChemDiv1_010908 COc1ccc(cc1)C2=C(C3C4C(C2C3=O)C(=O)N(C4=O)c5cccc6ccccc56)c7ccc(OC)cc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P19 compound treatment 512200.0 -75000.0 -0.34 526069.0 -35600.0 -0.18 -0.3621 -0.9549 1975332 ChemDiv1_010909 NS(=O)(=O)c1ccc(cc1)N2C(=O)c3cc(cc4cc(cc(C2=O)c34)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P20 compound treatment 632140.0 44900.0 0.2 626366.0 64700.0 0.32 0.3688 0.9749 1553530 ChemDiv1_010910 COC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(Br)cc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P21 compound treatment 705188.0 118000.0 0.53 695098.0 133000.0 0.66 0.8408 0.9938 1975333 ChemDiv1_010911 OC(=O)c1cc(ccc1Cl)N2C(=O)c3ccc([N+](=O)[O-])c4c(ccc(C2=O)c34)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P22 compound treatment 618179.0 31000.0 0.14 606783.0 45100.0 0.22 0.256 0.9737 1975334 ChemDiv1_010912 CCOC(=O)c1sc2nc(C)cc(COC)c2c1NC(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P23 mock treatment 626110.0 38900.0 0.17 576013.0 14300.0 0.07 0.1734 0.9216 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.617 P24 mock treatment 325676.0 -262000.0 -1.17 439054.0 -123000.0 -0.61 -1.2573 -0.9533 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A01 compound treatment 592693.0 9600.0 0.04 601128.0 3160.0 0.02 0.0415 0.9063 1655149 ChemDiv1_010913 CON(c1nc(OC)nc(n1)N(C)C)S(=O)(=O)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A02 compound treatment 575504.0 -7590.0 -0.03 606833.0 8860.0 0.04 0.007 0.1267 1975335 ChemDiv1_010914 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(NC(=O)C(F)(F)F)c3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A03 compound treatment 580281.0 -2810.0 -0.01 623508.0 25500.0 0.13 0.0806 0.6337 1975336 ChemDiv1_010915 CC/1=NN(C(=O)\C1=C/Nc2cc(cc(c2)[N+](=O)[O-])[N+](=O)[O-])c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A04 compound treatment 621204.0 38100.0 0.17 660530.0 62600.0 0.31 0.3398 0.9605 1975337 ChemDiv1_010916 NC1=C(C#N)C(C(=C(O1)c2ccccc2)C(=O)c3ccccc3)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A05 compound treatment 622253.0 39200.0 0.18 624994.0 27000.0 0.13 0.2186 0.9911 1975338 ChemDiv1_010917 Clc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A06 compound treatment 638867.0 55800.0 0.25 628112.0 30100.0 0.15 0.2821 0.9698 1323946 ChemDiv1_010918 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(C)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A07 compound treatment 633044.0 50000.0 0.22 645743.0 47800.0 0.24 0.3255 0.9996 1975339 ChemDiv1_010919 CCOC(=O)c1c(CBr)n(C)c2ccc(OS(=O)(=O)c3ccc(C)cc3)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A08 compound treatment 660052.0 77000.0 0.34 649057.0 51100.0 0.25 0.4226 0.9885 1975340 ChemDiv1_010920 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)C(F)(F)F)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A09 compound treatment 640338.0 57200.0 0.26 664667.0 66700.0 0.33 0.4148 0.9921 1185796 ChemDiv1_010921 Clc1ccc(cc1S(=O)(=O)Nc2ccc(NC(=O)c3ccccc3)cc2)C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A10 compound treatment 655861.0 72800.0 0.33 649608.0 51600.0 0.26 0.4112 0.9928 1975341 ChemDiv1_010922 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A11 compound treatment 646175.0 63100.0 0.28 653967.0 56000.0 0.28 0.3958 1.0 1552070 ChemDiv1_010923 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4C(=O)O)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A12 compound treatment 649201.0 66100.0 0.3 632538.0 34600.0 0.17 0.3303 0.9662 1975342 ChemDiv1_010924 NC1=C(C#N)C(C(=C(O1)c2ccccc2)n3cnc(c3)[N+](=O)[O-])c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A13 compound treatment 903642.0 321000.0 1.43 916389.0 318000.0 1.58 2.13 0.9989 1975343 ChemDiv1_010925 CCN1C/C(=C\c2ccccc2C)/C3=C(C1)C(C(=C(N)O3)C#N)c4ccccc4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A14 compound treatment 662109.0 79000.0 0.35 647076.0 49100.0 0.24 0.4221 0.9833 1975344 ChemDiv1_010926 CC(=O)N/C(=C\c1ccc(F)cc1)/C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A15 compound treatment 662185.0 79100.0 0.35 656284.0 58300.0 0.29 0.4546 0.9949 1631491 ChemDiv1_010927 CN(C)C(=O)CSc1nc2ccccc2n1C(=O)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A16 compound treatment 670380.0 87300.0 0.39 649210.0 51200.0 0.25 0.4558 0.9782 1719730 ChemDiv1_010928 CCCC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A17 compound treatment 656937.0 73800.0 0.33 652194.0 54200.0 0.27 0.4237 0.9947 1149118 ChemDiv1_010929 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A18 compound treatment 668920.0 85800.0 0.38 678942.0 81000.0 0.4 0.5553 0.9998 1975345 ChemDiv1_010930 COC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(Cl)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A19 compound treatment 644083.0 61000.0 0.27 659068.0 61100.0 0.3 0.4071 0.9987 1975346 ChemDiv1_010931 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A20 compound treatment 615740.0 32600.0 0.15 636771.0 38800.0 0.19 0.2393 0.9909 1975347 ChemDiv1_010932 COCCOC(=O)C1=C(COC)OC(=C(C(=O)OC)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A21 compound treatment 641803.0 58700.0 0.26 652084.0 54100.0 0.27 0.3754 1.0 1975348 ChemDiv1_010933 CN1CCN(CC1)C(=O)CSc2nc(cc(c2C#N)c3ccccc3)c4ccccc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A22 compound treatment 628877.0 45800.0 0.2 635684.0 37700.0 0.19 0.277 0.9989 1975349 ChemDiv1_010934 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cccc(c3)C(F)(F)F)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A23 mock treatment 594146.0 11100.0 0.05 613692.0 15700.0 0.08 0.0901 0.976 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 A24 mock treatment 508044.0 -75000.0 -0.34 507677.0 -90300.0 -0.45 -0.5538 -0.99 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B01 compound treatment 599090.0 16000.0 0.07 609021.0 11100.0 0.05 0.0894 0.9912 1975350 ChemDiv1_010935 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B02 compound treatment 618314.0 35200.0 0.16 656026.0 58100.0 0.29 0.3149 0.96 1975351 ChemDiv1_010936 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccnc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B03 compound treatment 690284.0 107000.0 0.48 730253.0 132000.0 0.66 0.8027 0.9883 1975352 ChemDiv1_010937 COCC1=C(C(C(=C(N)O1)C#N)c2c(F)cccc2Cl)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B04 compound treatment 654326.0 71200.0 0.32 689998.0 92000.0 0.46 0.5478 0.9847 1497707 ChemDiv1_010938 Fc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B05 compound treatment 699676.0 117000.0 0.52 711475.0 114000.0 0.56 0.7666 0.9993 1288353 ChemDiv1_010939 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(C)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B06 compound treatment 668420.0 85300.0 0.38 705776.0 108000.0 0.53 0.6477 0.9865 1501442 ChemDiv1_010940 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(SC)cc3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B07 compound treatment 715649.0 133000.0 0.59 753611.0 156000.0 0.77 0.9648 0.9916 1609666 ChemDiv1_010941 COc1cc(ccc1OCC(=O)OC(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B08 compound treatment 699949.0 117000.0 0.52 724876.0 127000.0 0.63 0.8144 0.9958 1975353 ChemDiv1_010942 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3cccnc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B09 compound treatment 704931.0 122000.0 0.55 754388.0 156000.0 0.77 0.9336 0.9852 1975354 ChemDiv1_010943 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)N(C4CCCCC4)C5CCCCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B10 compound treatment 696057.0 113000.0 0.51 721451.0 123000.0 0.61 0.7901 0.9955 1498038 ChemDiv1_010944 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC=C)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B11 compound treatment 726010.0 143000.0 0.64 743053.0 145000.0 0.72 0.9606 0.9983 1550112 ChemDiv1_010945 Cc1ccc(C)c(Nc2nc3nonc3nc2N4CCCCC4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B12 compound treatment 701792.0 119000.0 0.53 727385.0 129000.0 0.64 0.829 0.9956 1975355 ChemDiv1_010946 Cc1ccc(cc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OCc4ccccc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B13 compound treatment 724740.0 142000.0 0.63 762774.0 165000.0 0.82 1.0256 0.9922 1975356 ChemDiv1_010947 [O-][N+](=O)c1ccc(cc1)N2N=C(/C(=C/Nc3cccc(F)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B14 compound treatment 700259.0 117000.0 0.52 711024.0 113000.0 0.56 0.7669 0.9995 1145932 ChemDiv1_010948 Nc1c(oc2ccccc12)C(=O)c3ccc(Oc4ccccc4)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B15 compound treatment 737402.0 154000.0 0.69 758671.0 161000.0 0.8 1.0514 0.9975 1923822 ChemDiv1_010949 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccccn2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B16 compound treatment 711045.0 128000.0 0.57 739059.0 141000.0 0.7 0.8992 0.9951 1315222 ChemDiv1_010950 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc5OCOc5cc4Cl)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B17 compound treatment 733071.0 150000.0 0.67 777345.0 179000.0 0.89 1.1031 0.9904 1975357 ChemDiv1_010951 COc1ccc(Nc2nc(NCc3cccnc3)nc(NCc4cccnc4)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B18 compound treatment 711501.0 128000.0 0.57 714701.0 117000.0 0.58 0.8154 1.0 1975358 ChemDiv1_010952 [O-][N+](=O)c1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B19 compound treatment 721040.0 138000.0 0.62 747364.0 149000.0 0.74 0.96 0.9959 1678233 ChemDiv1_010953 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)N5CCOCC5)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B20 compound treatment 686093.0 103000.0 0.46 715623.0 118000.0 0.58 0.7382 0.9933 1975359 ChemDiv1_010954 Nn1cnn2c(SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(cc4)S(=O)(=O)N)s3)nnc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B21 compound treatment 723484.0 140000.0 0.63 773079.0 175000.0 0.87 1.0578 0.9875 1714590 ChemDiv1_010955 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)S(=O)(=O)N)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B22 compound treatment 666167.0 83100.0 0.37 703553.0 106000.0 0.52 0.6328 0.986 1975360 ChemDiv1_010956 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5cccc6ccccc56 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B23 mock treatment 664612.0 81500.0 0.36 682896.0 84900.0 0.42 0.5555 0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 B24 mock treatment 505740.0 -77400.0 -0.35 509572.0 -88400.0 -0.44 -0.5545 -0.9932 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C01 compound treatment 584535.0 1440.0 0.01 634994.0 37000.0 0.18 0.1343 0.7316 1975361 ChemDiv1_010957 [O-][N+](=O)c1ccccc1NC(=O)CSc2nc(ccc2C#N)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C02 compound treatment 631879.0 48800.0 0.22 639337.0 41400.0 0.2 0.2993 0.9995 1975362 ChemDiv1_010958 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CC(NC(=O)C(F)(F)F)c3ccccc3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C03 compound treatment 738012.0 155000.0 0.69 754276.0 156000.0 0.77 1.0379 0.9985 1975363 ChemDiv1_010959 CC(=O)C1=C(C)OC(=C(C#N)C1c2ccsc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C04 compound treatment 704606.0 122000.0 0.54 728125.0 130000.0 0.64 0.8405 0.9964 1975364 ChemDiv1_010960 Nc1nc(SCC(=O)Nc2ccccc2Br)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C05 compound treatment 691179.0 108000.0 0.48 722726.0 125000.0 0.62 0.7791 0.9927 1975365 ChemDiv1_010961 CCOC(=O)CC1=C(C(C(=C(N)O1)C#N)c2ccc(cc2)[N+](=O)[O-])C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C06 compound treatment 688142.0 105000.0 0.47 715904.0 118000.0 0.58 0.7456 0.9942 1975366 ChemDiv1_010962 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C07 compound treatment 709206.0 126000.0 0.56 753393.0 155000.0 0.77 0.9436 0.9884 1355436 ChemDiv1_010963 COc1ccc(NC(=O)CSc2nc3CCCCc3cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C08 compound treatment 706163.0 123000.0 0.55 784048.0 186000.0 0.92 1.0414 0.9697 1723941 ChemDiv1_010964 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(C)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C09 compound treatment 745799.0 163000.0 0.73 823800.0 226000.0 1.12 1.3061 0.9784 1548828 ChemDiv1_010965 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C10 compound treatment 742224.0 159000.0 0.71 790517.0 193000.0 0.95 1.1782 0.9897 1975367 ChemDiv1_010966 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C11 compound treatment 704643.0 122000.0 0.54 755304.0 157000.0 0.78 0.9359 0.9846 1975368 ChemDiv1_010967 ClCC(=O)Nc1ccc(cc1)c2nc(c3ccccc3)c4cc(NC(=O)CCl)ccc4n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C12 compound treatment 710579.0 127000.0 0.57 792784.0 195000.0 0.97 1.0859 0.9686 1925844 ChemDiv1_010968 CCOC(=O)c1ccc2nc(NC(=O)CSCC(=O)OCC(=O)c3ccc(Br)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C13 compound treatment 743936.0 161000.0 0.72 769159.0 171000.0 0.85 1.1088 0.9967 1975369 ChemDiv1_010969 COC(=O)C1=C(N)OC2=C(C1c3ccccc3F)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C14 compound treatment 748141.0 165000.0 0.74 803152.0 205000.0 1.02 1.2412 0.9877 1778165 ChemDiv1_010970 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2c(C)cc(C)c([N+](=O)[O-])c2C)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C15 compound treatment 751019.0 168000.0 0.75 803539.0 206000.0 1.02 1.2516 0.9888 1618465 ChemDiv1_010971 Cc1c(Nc2nc3nonc3nc2Nc4ccccc4C)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C16 compound treatment 724066.0 141000.0 0.63 762485.0 165000.0 0.81 1.0225 0.992 1140658 ChemDiv1_010972 CCCC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C17 compound treatment 745660.0 163000.0 0.73 777978.0 180000.0 0.89 1.1451 0.9949 1590324 ChemDiv1_010973 Oc1ccc(Nc2nc3nonc3nc2Nc4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C18 compound treatment 746272.0 163000.0 0.73 769361.0 171000.0 0.85 1.1169 0.9972 1975370 ChemDiv1_010974 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(c2)C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C19 compound treatment 756044.0 173000.0 0.77 789320.0 191000.0 0.95 1.2177 0.995 1975371 ChemDiv1_010975 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C20 compound treatment 709169.0 126000.0 0.56 748960.0 151000.0 0.75 0.928 0.9904 1975372 ChemDiv1_010976 COCC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C21 compound treatment 712985.0 130000.0 0.58 742264.0 144000.0 0.71 0.9166 0.9948 1504116 ChemDiv1_010977 COc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)N3CCN(C)CC3)n2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C22 compound treatment 668405.0 85300.0 0.38 735603.0 138000.0 0.68 0.7522 0.9625 1354184 ChemDiv1_010978 CC(C)(C)Nc1nc(NCc2cccnc2)nc(n1)N3CCOCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C23 mock treatment 673289.0 90200.0 0.4 714129.0 116000.0 0.58 0.6924 0.985 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 C24 mock treatment 512382.0 -70700.0 -0.32 521006.0 -77000.0 -0.38 -0.4934 -0.9957 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D01 compound treatment 583948.0 858.0 0.0 610358.0 12400.0 0.06 0.0461 0.7499 1165431 ChemDiv1_010979 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D02 compound treatment 617233.0 34100.0 0.15 660178.0 62200.0 0.31 0.326 0.9477 1975373 ChemDiv1_010980 Oc1ccccc1C(=O)N2N=C(CC2(O)c3ccncc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D03 compound treatment 731554.0 148000.0 0.66 740141.0 142000.0 0.7 0.9679 0.9996 1975374 ChemDiv1_010981 COCC1=C(C(C(=C(N)O1)C#N)c2ccsc2)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D04 compound treatment 664538.0 81400.0 0.36 696724.0 98800.0 0.49 0.6037 0.9895 1668393 ChemDiv1_010982 Brc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc5ccccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D05 compound treatment 688958.0 106000.0 0.47 724822.0 127000.0 0.63 0.7794 0.9903 1228992 ChemDiv1_010983 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(C)c4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D06 compound treatment 698632.0 116000.0 0.52 760675.0 163000.0 0.81 0.9357 0.977 1526254 ChemDiv1_010984 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc4OCOc4c3)C(=O)CCC2)c5ccc(Br)cn5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D07 compound treatment 690773.0 108000.0 0.48 718105.0 120000.0 0.6 0.7617 0.9945 1148713 ChemDiv1_010985 COc1cc(ccc1OCC=C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D08 compound treatment 727072.0 144000.0 0.64 753793.0 156000.0 0.77 1.0016 0.996 1975375 ChemDiv1_010986 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D09 compound treatment 731832.0 149000.0 0.67 771293.0 173000.0 0.86 1.0779 0.9921 1288977 ChemDiv1_010987 Clc1nc(NCCN2CCOCC2)nc(n1)N3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D10 compound treatment 713063.0 130000.0 0.58 734394.0 136000.0 0.68 0.8893 0.9972 1385896 ChemDiv1_010988 CC(=O)OC(OC(=O)C)C1(OC2C=C1)C3C2C(=O)N(C3=O)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D11 compound treatment 741711.0 159000.0 0.71 800818.0 203000.0 1.0 1.2126 0.9855 1631197 ChemDiv1_010989 Cc1c(Nc2nc3nonc3nc2Nc4ccc(F)cc4)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D12 compound treatment 721283.0 138000.0 0.62 749973.0 152000.0 0.75 0.9699 0.9952 1181555 ChemDiv1_010990 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc4OCOc4c3)C(=O)CCC2)c5ccc(cc5)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D13 compound treatment 802972.0 220000.0 0.98 807913.0 210000.0 1.04 1.4314 0.9996 1975376 ChemDiv1_010991 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cc(Br)cs3)N)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D14 compound treatment 886196.0 303000.0 1.36 874255.0 276000.0 1.37 1.9272 1.0 1975377 ChemDiv1_010992 O=C/1N(/C(=N/c2ccccc2)/S\C1=C/c3ccccn3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D15 compound treatment 758559.0 175000.0 0.79 773643.0 176000.0 0.87 1.1708 0.9987 1663544 ChemDiv1_010993 CC(=O)Nc1ccc2nc(SCc3ccc(Br)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D16 compound treatment 723788.0 141000.0 0.63 754264.0 156000.0 0.77 0.9928 0.9948 1575648 ChemDiv1_010994 CCc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D17 compound treatment 764412.0 181000.0 0.81 783290.0 185000.0 0.92 1.2231 0.9981 1671575 ChemDiv1_010995 CC1CCN(CC1)c2nc(Cl)nc(NCCN3CCOCC3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D18 compound treatment 715426.0 132000.0 0.59 722926.0 125000.0 0.62 0.8566 0.9998 1975378 ChemDiv1_010996 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CCc4ccccc4)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D19 compound treatment 711722.0 129000.0 0.58 730834.0 133000.0 0.66 0.8726 0.9978 1975379 ChemDiv1_010997 COc1ccc2[nH]c(Sc3ccc(cc3[N+](=O)[O-])C(F)(F)F)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D20 compound treatment 705967.0 123000.0 0.55 708388.0 110000.0 0.55 0.7757 1.0 1191511 ChemDiv1_010998 Oc1ccc(Nc2nc(Cl)nc(NCc3ccco3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D21 compound treatment 824582.0 241000.0 1.08 805405.0 207000.0 1.03 1.491 0.9997 1975380 ChemDiv1_010999 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccncc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D22 compound treatment 689978.0 107000.0 0.48 743173.0 145000.0 0.72 0.847 0.9804 1217860 ChemDiv1_011000 CCOC(=O)C1=C(N)N(C2=C(C1c3cccnc3)C(=O)CC(C)(C)C2)c4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D23 mock treatment 688624.0 106000.0 0.47 674815.0 76800.0 0.38 0.6032 0.9943 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 D24 mock treatment 518955.0 -64100.0 -0.29 519668.0 -78300.0 -0.39 -0.4773 -0.989 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E01 compound treatment 649932.0 66800.0 0.3 654780.0 56800.0 0.28 0.4106 0.9995 1617339 ChemDiv1_011001 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc3OCOc3c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E02 compound treatment 647085.0 64000.0 0.29 662158.0 64200.0 0.32 0.4274 0.9986 1930952 ChemDiv1_011002 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)c3ccc(Br)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E03 compound treatment 677388.0 94300.0 0.42 711769.0 114000.0 0.56 0.6971 0.9898 1975381 ChemDiv1_011003 ClCCc1ccc(cc1)S(=O)(=O)Nc2cccc3C(=O)c4ccccc4C(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E04 compound treatment 770032.0 187000.0 0.84 810302.0 212000.0 1.05 1.3355 0.9936 1975382 ChemDiv1_011004 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)Nc3ccccc3Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E05 compound treatment 711506.0 128000.0 0.57 733434.0 135000.0 0.67 0.881 0.997 1975383 ChemDiv1_011005 ClC1=CC2C3C(C1c4ccccc24)C(=O)N(C3=O)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E06 compound treatment 721796.0 139000.0 0.62 728246.0 130000.0 0.65 0.8954 0.9998 1783887 ChemDiv1_011006 COc1ccc(CCNC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E07 compound treatment 724642.0 142000.0 0.63 760867.0 163000.0 0.81 1.0187 0.9928 1695816 ChemDiv1_011007 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3[nH]2)sc4CCCc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E08 compound treatment 744212.0 161000.0 0.72 767708.0 170000.0 0.84 1.1046 0.9971 1975384 ChemDiv1_011008 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Cl)cc3)c4cc(Br)cs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E09 compound treatment 732576.0 149000.0 0.67 788533.0 191000.0 0.94 1.1407 0.9858 1975385 ChemDiv1_011009 CC(C)(COC(=O)c1ccc(Br)cc1)NC2=NS(=O)(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E10 compound treatment 724343.0 141000.0 0.63 736941.0 139000.0 0.69 0.9339 0.9991 1975386 ChemDiv1_011010 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E11 compound treatment 894726.0 312000.0 1.39 947006.0 349000.0 1.73 2.209 0.9943 1975387 ChemDiv1_011011 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2[N+](=O)[O-])n3nnc(n3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E12 compound treatment 754406.0 171000.0 0.77 784316.0 186000.0 0.92 1.195 0.9958 1975388 ChemDiv1_011012 CCNc1nc(OC)nc(n1)N2CC(=O)N(CC(=O)OCC)C2=N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E13 compound treatment 712263.0 129000.0 0.58 794134.0 196000.0 0.97 1.096 0.9692 1975389 ChemDiv1_011013 COC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CC(C)(C)C2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E14 compound treatment 755884.0 173000.0 0.77 753505.0 156000.0 0.77 1.0918 1.0 1597798 ChemDiv1_011014 CCOC(=O)c1c(CSc2nc(C)c(CC=C)c(C)c2C#N)n(C)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E15 compound treatment 760070.0 177000.0 0.79 820396.0 222000.0 1.1 1.3393 0.9869 1975390 ChemDiv1_011015 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5cccc(c5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E16 compound treatment 764915.0 182000.0 0.81 785952.0 188000.0 0.93 1.234 0.9977 1246881 ChemDiv1_011016 CCCC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E17 compound treatment 769018.0 186000.0 0.83 816729.0 219000.0 1.08 1.3548 0.9915 1975391 ChemDiv1_011017 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E18 compound treatment 745090.0 162000.0 0.73 773668.0 176000.0 0.87 1.1282 0.9959 1191298 ChemDiv1_011018 Fc1cccc(c1)c2cc(nc(SCC(=O)Nc3nc4ccccc4o3)c2C#N)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E19 compound treatment 762925.0 180000.0 0.81 786079.0 188000.0 0.93 1.2281 0.9973 1975392 ChemDiv1_011019 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccnc3)N)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E20 compound treatment 744659.0 162000.0 0.72 768075.0 170000.0 0.84 1.1073 0.9971 1975393 ChemDiv1_011020 CCOC(=O)C1=C(N)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E21 compound treatment 750078.0 167000.0 0.75 778877.0 181000.0 0.9 1.1623 0.9959 1975394 ChemDiv1_011021 CC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(cc32)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E22 compound treatment 713026.0 130000.0 0.58 765085.0 167000.0 0.83 0.9967 0.9851 1975395 ChemDiv1_011022 CC1SC2(N(C1=O)c3ccc(Cl)cc3)C(=O)Nc4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E23 mock treatment 693549.0 110000.0 0.49 750919.0 153000.0 0.76 0.8854 0.9786 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 E24 mock treatment 512906.0 -70200.0 -0.31 526115.0 -71900.0 -0.36 -0.4738 -0.9981 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F01 compound treatment 595058.0 12000.0 0.05 610844.0 12900.0 0.06 0.083 0.9962 1975396 ChemDiv1_011023 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F02 compound treatment 662744.0 79700.0 0.36 682423.0 84500.0 0.42 0.548 0.9968 1975397 ChemDiv1_011024 OC1(CC(=NN1C(=O)c2ccccc2F)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F03 compound treatment 730933.0 148000.0 0.66 756387.0 158000.0 0.78 1.0229 0.9964 1975398 ChemDiv1_011025 COCC1=C(C(C(=C(N)O1)C#N)c2cccc(Br)c2)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F04 compound treatment 678641.0 95600.0 0.43 683139.0 85200.0 0.42 0.6008 1.0 1975399 ChemDiv1_011026 CCC(C)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F05 compound treatment 712489.0 129000.0 0.58 731332.0 133000.0 0.66 0.8767 0.9979 1975400 ChemDiv1_011027 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C(=C\c3ccc(F)cc3)/NC(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F06 compound treatment 691120.0 108000.0 0.48 731532.0 134000.0 0.66 0.8098 0.9881 1475795 ChemDiv1_011028 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(F)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F07 compound treatment 708992.0 126000.0 0.56 759699.0 162000.0 0.8 0.965 0.9852 1975401 ChemDiv1_011029 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F08 compound treatment 730552.0 147000.0 0.66 743065.0 145000.0 0.72 0.975 0.9991 1975402 ChemDiv1_011030 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4C)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F09 compound treatment 717528.0 134000.0 0.6 766702.0 169000.0 0.84 1.0166 0.987 1975403 ChemDiv1_011031 Nc1nnc(SCC(=O)Nc2cc(cc(NC(=O)CSc3nnc(N)s3)c2Cl)C(F)(F)F)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F10 compound treatment 724587.0 141000.0 0.63 677088.0 79100.0 0.39 0.725 0.9734 1280237 ChemDiv1_011032 COc1cc(ccc1OCC(=O)OCc2ccccc2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F11 compound treatment 703045.0 120000.0 0.54 775427.0 177000.0 0.88 1.0013 0.972 1975404 ChemDiv1_011033 [O-][N+](=O)c1ccc(cc1)C(=O)COC(=O)CN2C(=O)c3ccc4CCc5ccc(C2=O)c3c45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F12 compound treatment 719454.0 136000.0 0.61 726224.0 128000.0 0.64 0.8809 0.9998 1975405 ChemDiv1_011034 Nc1nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F13 compound treatment 751855.0 169000.0 0.76 742541.0 145000.0 0.72 1.0406 0.9996 1975406 ChemDiv1_011035 Cn1nccc1C(=O)Nc2cc(Sc3nc4ccccc4s3)cc(c2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F14 compound treatment 735441.0 152000.0 0.68 741614.0 144000.0 0.71 0.9854 0.9998 1527070 ChemDiv1_011036 Brc1cccc(c1)C2Nc3ccccc3C(=O)N2c4ccc(I)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F15 compound treatment 740299.0 157000.0 0.7 746988.0 149000.0 0.74 1.0196 0.9997 1975407 ChemDiv1_011037 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)NCCCCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F16 compound treatment 743351.0 160000.0 0.72 755529.0 158000.0 0.78 1.0592 0.9991 1422453 ChemDiv1_011038 Brc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F17 compound treatment 744067.0 161000.0 0.72 755008.0 157000.0 0.78 1.0596 0.9993 1975408 ChemDiv1_011039 COc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccc(OC)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F18 compound treatment 726984.0 144000.0 0.64 759501.0 162000.0 0.8 1.0213 0.9942 1975409 ChemDiv1_011040 CN1CCN(CC1)c2ccc(cc2[N+](=O)[O-])C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F19 compound treatment 754223.0 171000.0 0.77 803740.0 206000.0 1.02 1.2625 0.9901 1742967 ChemDiv1_011041 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F20 compound treatment 743082.0 160000.0 0.72 743804.0 146000.0 0.72 1.0173 1.0 1281555 ChemDiv1_011042 C(Nc1nc(Nc2ccccc2)nc(Nc3ccccc3)n1)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F21 compound treatment 924316.0 341000.0 1.53 910181.0 312000.0 1.55 2.1737 1.0 1975410 ChemDiv1_011043 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(F)cc3)c4cc(Br)cs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F22 compound treatment 674528.0 91400.0 0.41 730092.0 132000.0 0.65 0.7522 0.9745 1975411 ChemDiv1_011044 CCOC(=O)c1nnn(c1CSc2nc3ccccc3[nH]2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F23 mock treatment 688702.0 106000.0 0.47 700473.0 103000.0 0.51 0.6933 0.9994 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 F24 mock treatment 512409.0 -70700.0 -0.32 544783.0 -53200.0 -0.26 -0.41 -0.9959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G01 compound treatment 606795.0 23700.0 0.11 615592.0 17600.0 0.09 0.1368 0.9953 1975412 ChemDiv1_011045 CCOC(=O)C1=C(C)NC(=O)NC1c2cc(C)cc(c2)N(CCCl)CCCl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G02 compound treatment 639485.0 56400.0 0.25 664031.0 66100.0 0.33 0.4099 0.9918 1975413 ChemDiv1_011046 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G03 compound treatment 710521.0 127000.0 0.57 721926.0 124000.0 0.61 0.8376 0.9993 1975414 ChemDiv1_011047 Oc1ccccc1/C=C\2/SC(=O)N(CNc3cccc(Br)c3)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G04 compound treatment 706852.0 124000.0 0.55 704169.0 106000.0 0.53 0.7637 0.9997 1975415 ChemDiv1_011048 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G05 compound treatment 711680.0 129000.0 0.58 711135.0 113000.0 0.56 0.8034 0.9999 1975416 ChemDiv1_011049 COc1ccc(/C=C/2\N=C(OC2=O)c3cc(ccc3Cl)[N+](=O)[O-])cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G06 compound treatment 682153.0 99100.0 0.44 709591.0 112000.0 0.55 0.7046 0.994 1616634 ChemDiv1_011050 CCOC(=O)c1c(CNc2ccccc2C(=O)N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G07 compound treatment 721353.0 138000.0 0.62 732549.0 135000.0 0.67 0.9091 0.9993 1197451 ChemDiv1_011051 COc1ccc(N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G08 compound treatment 715628.0 133000.0 0.59 756234.0 158000.0 0.78 0.9739 0.9905 1975417 ChemDiv1_011052 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccc(cc3)C4=N/C(=C\c5ccc(C)o5)/C(=O)O4)o1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G09 compound treatment 778380.0 195000.0 0.87 746058.0 148000.0 0.73 1.1369 0.9962 1126309 ChemDiv1_011053 CC(=O)Nc1cc(O)nc(NC(=O)C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G10 compound treatment 707183.0 124000.0 0.56 757403.0 159000.0 0.79 0.9513 0.9852 1975418 ChemDiv1_011054 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccc(c3)[N+](=O)[O-])N)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G11 compound treatment 740874.0 158000.0 0.71 775303.0 177000.0 0.88 1.1206 0.9942 1354908 ChemDiv1_011055 Nn1cnn2c(SCC(=O)N3CCN(CC3)C(=O)CSc4nnc5n(N)cnn45)nnc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G12 compound treatment 730336.0 147000.0 0.66 781026.0 183000.0 0.91 1.1073 0.9877 1137142 ChemDiv1_011056 CCN(CC)c1nc2nonc2nc1N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G13 compound treatment 731277.0 148000.0 0.66 796279.0 198000.0 0.98 1.1637 0.9817 1212612 ChemDiv1_011057 CCOC(=O)COc1ccc2ccccc2c1C3NC(=O)NC(=C3C(=O)OCC)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G14 compound treatment 769079.0 186000.0 0.83 781628.0 184000.0 0.91 1.232 0.999 1657104 ChemDiv1_011058 CC(=O)Oc1c(Cl)cc(cc1Cl)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G15 compound treatment 764678.0 182000.0 0.81 798155.0 200000.0 0.99 1.276 0.9951 1975419 ChemDiv1_011059 FC(F)(F)c1cccc(c1)N(CC(=O)N2CCN(CC2)c3ccccc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G16 compound treatment 759053.0 176000.0 0.79 792380.0 194000.0 0.96 1.238 0.995 1975420 ChemDiv1_011060 COCCOC(=O)C1=C(C)OC(=C(C(=O)OC(C)C)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G17 compound treatment 786029.0 203000.0 0.91 764176.0 166000.0 0.82 1.2246 0.9988 1358220 ChemDiv1_011061 CCOC(=O)c1c2CN(Cc3ccccc3)CCn2c4cc(Br)c(OC)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G18 compound treatment 733194.0 150000.0 0.67 759993.0 162000.0 0.8 1.0427 0.9961 1975421 ChemDiv1_011062 CC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2F)C(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G19 compound treatment 772034.0 189000.0 0.85 816611.0 219000.0 1.08 1.3639 0.9925 1639893 ChemDiv1_011063 Cc1cc2OC(=C(C(=O)OCc3ccccc3)C4(C(=O)Nc5ccccc54)c2c(=O)o1)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G20 compound treatment 728103.0 145000.0 0.65 735570.0 138000.0 0.68 0.941 0.9997 1975422 ChemDiv1_011064 COCCOC(=O)C1=C(C)OC(=C(C(=O)OCc2ccccc2)C31C(=O)Nc4ccccc43)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G21 compound treatment 741803.0 159000.0 0.71 750621.0 153000.0 0.76 1.0371 0.9995 1975423 ChemDiv1_011065 CC1=C(C(=O)OCC=C)C2(C(=O)Nc3ccc(cc32)[N+](=O)[O-])C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G22 compound treatment 684996.0 102000.0 0.46 764109.0 166000.0 0.82 0.9045 0.9613 1719857 ChemDiv1_011066 O=C1CSC(N1c2ccc(cc2)N3C(SCC3=O)c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G23 mock treatment 703517.0 120000.0 0.54 739352.0 141000.0 0.7 0.8764 0.9916 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 G24 mock treatment 492131.0 -91000.0 -0.41 509181.0 -88800.0 -0.44 -0.5989 -0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H01 compound treatment 2404447.0 1820000.0 8.15 2219481.0 1620000.0 8.03 11.445 1.0 1187282 ChemDiv1_011067 CC(=O)OCc1c(C)ccc(C2C(=C(N)OC(=C2C#N)N)C#N)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H02 compound treatment 640985.0 57900.0 0.26 626655.0 28700.0 0.14 0.2837 0.96 1975424 ChemDiv1_011068 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccccc3[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H03 compound treatment 708081.0 125000.0 0.56 697727.0 99800.0 0.49 0.7451 0.9981 1975425 ChemDiv1_011069 COc1cccc(c1)c2cc(c(C#N)c(SCC(=O)NC3CC3)n2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H04 compound treatment 679927.0 96800.0 0.43 693574.0 95600.0 0.47 0.6414 0.999 1463275 ChemDiv1_011070 Clc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H05 compound treatment 738825.0 156000.0 0.7 759167.0 161000.0 0.8 1.0576 0.9977 1975426 ChemDiv1_011071 COc1cc(C=c2sc3nc4ccccc4n3c2=O)c(cc1OCc5ccccc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H06 compound treatment 688290.0 105000.0 0.47 748785.0 151000.0 0.75 0.8613 0.9752 1975427 ChemDiv1_011072 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H07 compound treatment 682669.0 99600.0 0.45 721051.0 123000.0 0.61 0.7463 0.9881 1282764 ChemDiv1_011073 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccccc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H08 compound treatment 690131.0 107000.0 0.48 732771.0 135000.0 0.67 0.811 0.9867 1780068 ChemDiv1_011074 CCSc1nc2ccccc2n1Cc3ccc(OC)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H09 compound treatment 756702.0 174000.0 0.78 763941.0 166000.0 0.82 1.1309 0.9996 1975428 ChemDiv1_011075 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H10 compound treatment 681522.0 98400.0 0.44 710021.0 112000.0 0.56 0.7041 0.9935 1371416 ChemDiv1_011076 CCCCc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H11 compound treatment 699553.0 116000.0 0.52 715008.0 117000.0 0.58 0.7786 0.9986 1975429 ChemDiv1_011077 COc1cccc(c1)C2(O)CC(=NN2C(=O)Cc3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H12 compound treatment 740095.0 157000.0 0.7 751655.0 154000.0 0.76 1.0353 0.9992 1975430 ChemDiv1_011078 COc1cc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(Br)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H13 compound treatment 753199.0 170000.0 0.76 770936.0 173000.0 0.86 1.1443 0.9983 1975431 ChemDiv1_011079 CCN(CC)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H14 compound treatment 728719.0 146000.0 0.65 716835.0 119000.0 0.59 0.8773 0.9987 1975432 ChemDiv1_011080 CCOC(=O)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H15 compound treatment 777690.0 195000.0 0.87 772986.0 175000.0 0.87 1.229 1.0 1207201 ChemDiv1_011081 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3C)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H16 compound treatment 751252.0 168000.0 0.75 722904.0 125000.0 0.62 0.9699 0.9953 1538222 ChemDiv1_011082 Cc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H17 compound treatment 734820.0 152000.0 0.68 774637.0 177000.0 0.88 1.0991 0.9921 1975433 ChemDiv1_011083 OC1(CC(=NN1C(=O)c2ccccc2F)C(F)(F)F)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H18 compound treatment 727423.0 144000.0 0.65 738985.0 141000.0 0.7 0.9508 0.9992 1453435 ChemDiv1_011084 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)c3ccc(cc3)N4C(=O)CCC4=O)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H19 compound treatment 736648.0 154000.0 0.69 766928.0 169000.0 0.84 1.0779 0.9952 1655986 ChemDiv1_011085 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H20 compound treatment 698784.0 116000.0 0.52 716622.0 119000.0 0.59 0.7818 0.998 1975434 ChemDiv1_011086 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(OC)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H21 compound treatment 722655.0 140000.0 0.62 776601.0 179000.0 0.88 1.0675 0.9855 1779030 ChemDiv1_011087 Cc1cccc(Nc2nc3nonc3nc2N4CCC(Cc5ccccc5)CC4)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H22 compound treatment 791457.0 208000.0 0.93 828590.0 231000.0 1.14 1.4674 0.9949 1684809 ChemDiv1_011088 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H23 mock treatment 691700.0 109000.0 0.49 685186.0 87200.0 0.43 0.6493 0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 H24 mock treatment 541718.0 -41400.0 -0.19 515460.0 -82500.0 -0.41 -0.42 -0.9359 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I01 compound treatment 590213.0 7120.0 0.03 597428.0 -542.0 0.0 0.0206 0.6453 1975435 ChemDiv1_011089 CC/1=NN(C(=O)\C1=C/Nc2ccc([N+](=O)[O-])c(c2)[N+](=O)[O-])c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I02 compound treatment 674362.0 91300.0 0.41 699843.0 102000.0 0.5 0.6457 0.9945 1975436 ChemDiv1_011090 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Br)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I03 compound treatment 746699.0 164000.0 0.73 776157.0 178000.0 0.88 1.142 0.9957 1975437 ChemDiv1_011091 COc1cc(cc(OC)c1OC)C2C(=C(N)OC(=C2C(=O)C)C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I04 compound treatment 682587.0 99500.0 0.45 712289.0 114000.0 0.57 0.7154 0.9929 1402704 ChemDiv1_011092 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(OC)cc2OC)S(=O)(=O)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I05 compound treatment 705699.0 123000.0 0.55 738051.0 140000.0 0.69 0.8788 0.9933 1275934 ChemDiv1_011093 COC(=O)COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I06 compound treatment 712337.0 129000.0 0.58 697137.0 99200.0 0.49 0.7565 0.9967 1291053 ChemDiv1_011094 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(OC)c(OC)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I07 compound treatment 740692.0 158000.0 0.71 723528.0 126000.0 0.62 0.9387 0.998 1975438 ChemDiv1_011095 FC(F)(F)c1cccc(c1)N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I08 compound treatment 719025.0 136000.0 0.61 737695.0 140000.0 0.69 0.9197 0.9979 1975439 ChemDiv1_011096 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I09 compound treatment 680527.0 97400.0 0.44 762913.0 165000.0 0.82 0.8862 0.9568 1296016 ChemDiv1_011097 NNC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I10 compound treatment 716404.0 133000.0 0.6 764212.0 166000.0 0.82 1.0043 0.9875 1975440 ChemDiv1_011098 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cc(Br)cs3)N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I11 compound treatment 761528.0 178000.0 0.8 836057.0 238000.0 1.18 1.3988 0.982 1975441 ChemDiv1_011099 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccccn2)c1C#N)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I12 compound treatment 712948.0 130000.0 0.58 726023.0 128000.0 0.63 0.8596 0.999 1975442 ChemDiv1_011100 COc1ccc(OC)c(c1)N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I13 compound treatment 706795.0 124000.0 0.55 762148.0 164000.0 0.81 0.9667 0.9824 1975443 ChemDiv1_011101 COc1ccc(Br)cc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I14 compound treatment 737200.0 154000.0 0.69 769466.0 171000.0 0.85 1.0885 0.9947 1401766 ChemDiv1_011102 COC(=O)COc1ccc(cc1OC)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I15 compound treatment 782445.0 199000.0 0.89 804639.0 207000.0 1.02 1.3549 0.9977 1948034 ChemDiv1_011103 COc1ccc(cc1)C(NC2=NS(=O)(=O)c3cc(ccc23)[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I16 compound treatment 698288.0 115000.0 0.52 761342.0 163000.0 0.81 0.9369 0.9763 1104610 ChemDiv1_011104 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccccc2Cl)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I17 compound treatment 826815.0 244000.0 1.09 836130.0 238000.0 1.18 1.6057 0.9992 1975444 ChemDiv1_011105 CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)n3nnc(n3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I18 compound treatment 726164.0 143000.0 0.64 748495.0 151000.0 0.75 0.9801 0.9971 1975445 ChemDiv1_011106 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I19 compound treatment 744688.0 162000.0 0.72 742350.0 144000.0 0.72 1.0172 1.0 1592099 ChemDiv1_011107 CC1=C(C(=O)OC(C)(C)C)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I20 compound treatment 723707.0 141000.0 0.63 745880.0 148000.0 0.73 0.9632 0.9971 1975446 ChemDiv1_011108 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)C(F)(F)F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I21 compound treatment 846429.0 263000.0 1.18 874270.0 276000.0 1.37 1.8014 0.9972 1975447 ChemDiv1_011109 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)NC4CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I22 compound treatment 717875.0 135000.0 0.6 766032.0 168000.0 0.83 1.0153 0.9875 1975448 ChemDiv1_011110 COc1ccc(cc1)N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccc(C)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I23 mock treatment 703841.0 121000.0 0.54 713918.0 116000.0 0.57 0.7884 0.9995 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 I24 mock treatment 515220.0 -67900.0 -0.3 510683.0 -87300.0 -0.43 -0.5206 -0.9851 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J01 compound treatment 597776.0 14700.0 0.07 596855.0 -1110.0 -0.01 0.0426 0.6454 1975449 ChemDiv1_011111 [O-][N+](=O)c1ccc(cc1)N2C(=O)C3C4OC(CNC(=O)COc5ccccc5)(C=C4)C3C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J02 compound treatment 643121.0 60000.0 0.27 654034.0 56100.0 0.28 0.3864 0.9999 1630350 ChemDiv1_011112 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc(Cl)cc5)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J03 compound treatment 677668.0 94600.0 0.42 731061.0 133000.0 0.66 0.7656 0.9771 1975450 ChemDiv1_011113 CCOC(=O)CC(=O)CSc1nc(cc(C)c1C#N)c2cccnc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J04 compound treatment 666665.0 83600.0 0.37 643984.0 46000.0 0.23 0.4257 0.9718 1975451 ChemDiv1_011114 OCCCNc1ccc([N+](=O)[O-])c(Sc2nc3ccccc3[nH]2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J05 compound treatment 697349.0 114000.0 0.51 715894.0 118000.0 0.58 0.7747 0.9978 1975452 ChemDiv1_011115 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccccc4C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J06 compound treatment 687975.0 105000.0 0.47 663834.0 65900.0 0.33 0.5627 0.9842 1975453 ChemDiv1_011116 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc([N+](=O)[O-])c(OC)cc3OC)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J07 compound treatment 741255.0 158000.0 0.71 716947.0 119000.0 0.59 0.9174 0.9958 1975454 ChemDiv1_011117 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J08 compound treatment 776745.0 194000.0 0.87 755299.0 157000.0 0.78 1.1641 0.9986 1975455 ChemDiv1_011118 CCOc1cc(/C=C\2/SC(=S)N(C)C2=O)ccc1OC(=O)c3ccc(cc3[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J09 compound treatment 755452.0 172000.0 0.77 745350.0 147000.0 0.73 1.0618 0.9996 1975456 ChemDiv1_011119 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J10 compound treatment 697717.0 115000.0 0.51 730297.0 132000.0 0.66 0.8264 0.9927 1671883 ChemDiv1_011120 Cc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J11 compound treatment 751691.0 169000.0 0.75 761744.0 164000.0 0.81 1.1073 0.9993 1975457 ChemDiv1_011121 Cc1c(NS(=O)(=O)c2ccc3C(=O)c4ccccc4C(=O)c3c2)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J12 compound treatment 777245.0 194000.0 0.87 818260.0 220000.0 1.09 1.3862 0.9936 1975458 ChemDiv1_011122 Nc1nc(SCC(=O)c2ccc(cc2)c3ccccc3)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J13 compound treatment 762864.0 180000.0 0.8 761865.0 164000.0 0.81 1.1431 1.0 1975459 ChemDiv1_011123 [O-][N+](=O)c1ccc(cc1)N2N=C(/C(=C/Nc3ccc(Cl)c(Cl)c3)/C2=O)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J14 compound treatment 712137.0 129000.0 0.58 763130.0 165000.0 0.82 0.987 0.9855 1572921 ChemDiv1_011124 CCN(CC)c1ccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(OCc5ccc(Cl)cc5)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J15 compound treatment 752693.0 170000.0 0.76 772949.0 175000.0 0.87 1.1498 0.9978 1975460 ChemDiv1_011125 [O-][N+](=O)c1ccc2nc(NC(=O)CSc3nc4ccccc4[nH]3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J16 compound treatment 751240.0 168000.0 0.75 741665.0 144000.0 0.71 1.0356 0.9996 1211342 ChemDiv1_011126 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc(Cl)cc5Cl)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J17 compound treatment 751404.0 168000.0 0.75 771114.0 173000.0 0.86 1.1393 0.9979 1363309 ChemDiv1_011127 O=C(CSCC(=O)Nc1ccc2nc(SCC(=O)Nc3ccccc3)sc2c1)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J18 compound treatment 727675.0 145000.0 0.65 724359.0 126000.0 0.63 0.9004 0.9999 1975461 ChemDiv1_011128 [O-][N+](=O)c1ccc(Nc2nc(NCc3ccco3)nc(Nc4ccc(Cl)cc4)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J19 compound treatment 726743.0 144000.0 0.64 758278.0 160000.0 0.79 1.0162 0.9945 1975462 ChemDiv1_011129 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccccc4C(F)(F)F)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J20 compound treatment 708403.0 125000.0 0.56 727110.0 129000.0 0.64 0.849 0.9979 1975463 ChemDiv1_011130 Nc1nc(SCC(=O)N(c2ccccc2)c3ccccc3)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J21 compound treatment 791042.0 208000.0 0.93 788340.0 190000.0 0.94 1.3251 1.0 1975464 ChemDiv1_011131 [O-][N+](=O)c1cc2OCOc2cc1C=C3C(=O)N(C(=S)N(C3=O)c4ccccc4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J22 compound treatment 704760.0 122000.0 0.54 727236.0 129000.0 0.64 0.8379 0.9968 1975465 ChemDiv1_011132 COC(=O)C1=C(N)N(C2=C(C1c3ccc(cc3)[N+](=O)[O-])C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J23 mock treatment 708554.0 125000.0 0.56 716718.0 119000.0 0.59 0.8131 0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 J24 mock treatment 532900.0 -50200.0 -0.22 538546.0 -59400.0 -0.29 -0.367 -0.9911 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K01 compound treatment 575765.0 -7330.0 -0.03 594278.0 -3690.0 -0.02 -0.0361 -0.962 1975466 ChemDiv1_011133 CC/1=NN(C(=O)\C1=C/Nc2c(Cl)cc(Cl)cc2Cl)c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K02 compound treatment 633456.0 50400.0 0.23 649997.0 52000.0 0.26 0.3417 0.9978 1975467 ChemDiv1_011134 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K03 compound treatment 658191.0 75100.0 0.34 689155.0 91200.0 0.45 0.5571 0.9894 1975468 ChemDiv1_011135 Cc1cc(c(C#N)c(SCC(=O)Nc2ccccc2[N+](=O)[O-])n1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K04 compound treatment 661168.0 78100.0 0.35 703225.0 105000.0 0.52 0.6158 0.9811 1975469 ChemDiv1_011136 COc1ccc(OC)c(c1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K05 compound treatment 666743.0 83700.0 0.37 687294.0 89300.0 0.44 0.5777 0.9966 1975470 ChemDiv1_011137 CCCCCOc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K06 compound treatment 689505.0 106000.0 0.48 688732.0 90800.0 0.45 0.6548 0.9996 1163654 ChemDiv1_011138 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K07 compound treatment 694843.0 112000.0 0.5 692603.0 94600.0 0.47 0.6852 0.9995 1491109 ChemDiv1_011139 CCOC(=O)c1c(CN2CCOCC2)n(CC(=O)OC)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K08 compound treatment 704282.0 121000.0 0.54 715772.0 118000.0 0.58 0.7963 0.9993 1482314 ChemDiv1_011140 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K09 compound treatment 721041.0 138000.0 0.62 705544.0 108000.0 0.53 0.8135 0.9973 1578834 ChemDiv1_011141 OC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K10 compound treatment 692290.0 109000.0 0.49 702421.0 104000.0 0.52 0.7115 0.9996 1306844 ChemDiv1_011142 COc1cccc(c1)C(=O)N(C2CC(C)N(C(=O)C)c3ccccc23)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K11 compound treatment 962040.0 379000.0 1.7 1135137.0 537000.0 2.66 3.0811 0.9764 1975471 ChemDiv1_011143 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)Nc4ccccn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K12 compound treatment 675874.0 92800.0 0.42 640091.0 42100.0 0.21 0.4412 0.9493 1975472 ChemDiv1_011144 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4ccc(Br)cc4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K13 compound treatment 697929.0 115000.0 0.51 741266.0 143000.0 0.71 0.8654 0.9874 1248627 ChemDiv1_011145 COc1cc(ccc1OCc2ccc(Cl)cc2Cl)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K14 compound treatment 696513.0 113000.0 0.51 761774.0 164000.0 0.81 0.9328 0.9745 1975473 ChemDiv1_011146 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)c3ccc(NC(=O)C(F)(F)F)cc3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K15 compound treatment 738165.0 155000.0 0.69 762214.0 164000.0 0.81 1.0662 0.9969 1267513 ChemDiv1_011147 CCOC(=O)c1oc2ccc(Cl)cc2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K16 compound treatment 741608.0 159000.0 0.71 767110.0 169000.0 0.84 1.0942 0.9966 1975474 ChemDiv1_011148 COCC1=C(C(C(=C(N)O1)C#N)c2cccc(Cl)c2)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K17 compound treatment 760513.0 177000.0 0.79 752911.0 155000.0 0.77 1.1043 0.9999 1975475 ChemDiv1_011149 CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)n3cnc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K18 compound treatment 687422.0 104000.0 0.47 738215.0 140000.0 0.69 0.8215 0.9813 1975476 ChemDiv1_011150 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccccc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K19 compound treatment 743208.0 160000.0 0.72 774271.0 176000.0 0.87 1.1244 0.9952 1975477 ChemDiv1_011151 Fc1ccc(cc1)c2cc(nc(SCC(=O)NC3CC3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K20 compound treatment 725748.0 143000.0 0.64 758016.0 160000.0 0.79 1.0122 0.9942 1937538 ChemDiv1_011152 COc1ccc2nc(NC(=O)COC(=O)C(CCSC)NC(=O)c3ccccc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K21 compound treatment 946235.0 363000.0 1.63 943396.0 345000.0 1.71 2.3594 0.9997 1975478 ChemDiv1_011153 COc1ccc(cc1OC)C(=O)CSc2nc(ccc2C#N)c3cccs3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K22 compound treatment 711926.0 129000.0 0.58 736013.0 138000.0 0.68 0.8913 0.9964 1418024 ChemDiv1_011154 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OCC)cc3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K23 mock treatment 685419.0 102000.0 0.46 729198.0 131000.0 0.65 0.7836 0.9853 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 K24 mock treatment 494434.0 -88700.0 -0.4 234743.0 -363000.0 -1.8 -1.553 -0.8428 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L01 compound treatment 602212.0 19100.0 0.09 604120.0 6150.0 0.03 0.0821 0.9033 1555602 ChemDiv1_011155 C(CN1CCOCC1)Nc2nc(Oc3ccccc3)nc(Oc4ccccc4)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L02 compound treatment 650664.0 67600.0 0.3 661622.0 63700.0 0.32 0.4369 0.9998 1975479 ChemDiv1_011156 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4cccc(C)c4)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L03 compound treatment 724082.0 141000.0 0.63 726858.0 129000.0 0.64 0.8978 1.0 1975480 ChemDiv1_011157 COc1ccc(cc1)C(=O)CSc2nc(cc(C)c2C#N)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L04 compound treatment 675534.0 92400.0 0.41 676832.0 78900.0 0.39 0.5689 0.9996 1975481 ChemDiv1_011158 CC(=O)OCCn1c(=O)c2ccc3c(=O)n(CCOC(=O)C)c(=O)c4ccc(c1=O)c2c34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L05 compound treatment 697249.0 114000.0 0.51 688584.0 90600.0 0.45 0.6788 0.9979 1164182 ChemDiv1_011159 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(C)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L06 compound treatment 707806.0 125000.0 0.56 695545.0 97600.0 0.48 0.7366 0.9974 1975482 ChemDiv1_011160 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4cccc(c4)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L07 compound treatment 702232.0 119000.0 0.53 707691.0 110000.0 0.54 0.7615 1.0 1975483 ChemDiv1_011161 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L08 compound treatment 695755.0 113000.0 0.5 709362.0 111000.0 0.55 0.7468 0.999 1975484 ChemDiv1_011162 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cn4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L09 compound treatment 752840.0 170000.0 0.76 711580.0 114000.0 0.56 0.9353 0.9891 1975485 ChemDiv1_011163 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cc(ccc3Cl)C(F)(F)F)c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L10 compound treatment 723057.0 140000.0 0.63 726814.0 129000.0 0.64 0.8944 1.0 1640332 ChemDiv1_011164 Clc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L11 compound treatment 798208.0 215000.0 0.96 813857.0 216000.0 1.07 1.4371 0.9986 1617717 ChemDiv1_011165 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(Cl)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L12 compound treatment 715714.0 133000.0 0.59 746960.0 149000.0 0.74 0.9417 0.9942 1567359 ChemDiv1_011166 CCN1C(=C(C(NC1=O)c2cc(Br)c(O)c(OC)c2)C(=O)OC(C)C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L13 compound treatment 720099.0 137000.0 0.61 723062.0 125000.0 0.62 0.8719 1.0 1354388 ChemDiv1_011167 Clc1ccc(cc1)C(=O)Nc2nnc(CCS(=O)(=O)c3ccc4ccccc4c3)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L14 compound treatment 673012.0 89900.0 0.4 744849.0 147000.0 0.73 0.7991 0.961 1975486 ChemDiv1_011168 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccc(C)cc4)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L15 compound treatment 710140.0 127000.0 0.57 718255.0 120000.0 0.6 0.8235 0.9997 1975487 ChemDiv1_011169 CC(C)(C)Nc1nc(Cl)nc(Nc2cccc(c2)[N+](=O)[O-])n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L16 compound treatment 745511.0 162000.0 0.73 743414.0 145000.0 0.72 1.0236 1.0 1975488 ChemDiv1_011170 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4C(F)(F)F)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L17 compound treatment 740760.0 158000.0 0.71 731793.0 134000.0 0.66 0.9678 0.9995 1975489 ChemDiv1_011171 CCOC(=O)c1c(CN2CCOCC2)n(C)c3ccc(OS(=O)(=O)c4ccc(C)cc4)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L18 compound treatment 713876.0 131000.0 0.59 714642.0 117000.0 0.58 0.8227 1.0 1361982 ChemDiv1_011172 Fc1cccc(C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5)c1F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L19 compound treatment 758905.0 176000.0 0.79 732944.0 135000.0 0.67 1.0293 0.9967 1975490 ChemDiv1_011173 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(Br)s3)C(=O)CCC2)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L20 compound treatment 724936.0 142000.0 0.63 757944.0 160000.0 0.79 1.0094 0.994 1975491 ChemDiv1_011174 OC1(CC(=NN1C(=O)c2ccccc2[N+](=O)[O-])C(F)(F)F)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L21 compound treatment 765273.0 182000.0 0.82 780900.0 183000.0 0.91 1.2174 0.9986 1169857 ChemDiv1_011175 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(C)c4C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L22 compound treatment 698303.0 115000.0 0.52 732026.0 134000.0 0.66 0.8343 0.9922 1608957 ChemDiv1_011176 Brc1ccccc1C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L23 mock treatment 714310.0 131000.0 0.59 720599.0 123000.0 0.61 0.8449 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 L24 mock treatment 529627.0 -53500.0 -0.24 514070.0 -83900.0 -0.42 -0.4631 -0.9656 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M01 compound treatment 584525.0 1430.0 0.01 592814.0 -5160.0 -0.03 -0.0135 -0.5133 1975492 ChemDiv1_011177 CCOc1ccc(N/C=C\2/C(=NN(C2=O)c3cccc(Cl)c3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M02 compound treatment 654423.0 71300.0 0.32 673073.0 75100.0 0.37 0.4889 0.9971 1975493 ChemDiv1_011178 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc(Br)s3)N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M03 compound treatment 681455.0 98400.0 0.44 694543.0 96600.0 0.48 0.6496 0.9991 1975494 ChemDiv1_011179 COc1ccc(N(CC(=O)NCCSc2ccc(Cl)cc2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M04 compound treatment 656539.0 73400.0 0.33 695273.0 97300.0 0.48 0.5733 0.9826 1264363 ChemDiv1_011180 COc1ccc(N(CC(=O)Nc2ccc(Br)cc2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M05 compound treatment 698414.0 115000.0 0.52 684408.0 86400.0 0.43 0.6678 0.9957 1975495 ChemDiv1_011181 COC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M06 compound treatment 659510.0 76400.0 0.34 661862.0 63900.0 0.32 0.4657 0.9992 1975496 ChemDiv1_011182 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(cc4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M07 compound treatment 741688.0 159000.0 0.71 748321.0 150000.0 0.74 1.0287 0.9997 1501366 ChemDiv1_011183 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M08 compound treatment 687006.0 104000.0 0.47 659284.0 61300.0 0.3 0.5437 0.9787 1975497 ChemDiv1_011184 OC1(CC(=NN1C(=O)c2ccc(Cl)cc2)C(F)(F)F)c3cccnc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M09 compound treatment 718667.0 136000.0 0.61 718715.0 121000.0 0.6 0.8521 1.0 1490070 ChemDiv1_011185 O=C1N(CCCN2C(=O)C3(OCCO3)c4ccccc24)c5ccccc5C61OCCO6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M10 compound treatment 689002.0 106000.0 0.47 727083.0 129000.0 0.64 0.7875 0.9891 1975498 ChemDiv1_011186 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4cccc(c4)[N+](=O)[O-])N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M11 compound treatment 735996.0 153000.0 0.68 746612.0 149000.0 0.74 1.0047 0.9993 1975499 ChemDiv1_011187 Cc1cccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M12 compound treatment 687260.0 104000.0 0.47 701756.0 104000.0 0.51 0.6933 0.9988 1975500 ChemDiv1_011188 CC1=NN(C(=O)c2ccccc2Br)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M13 compound treatment 713063.0 130000.0 0.58 747805.0 150000.0 0.74 0.9363 0.9927 1975501 ChemDiv1_011189 COC(=O)c1ccc2nc(NC(=O)CSCC(=O)OCC(=O)c3ccc(Br)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M14 compound treatment 704570.0 121000.0 0.54 701848.0 104000.0 0.51 0.7484 0.9996 1975502 ChemDiv1_011190 COCCOC(=O)C1=C(C)OC(=C(C(=O)OCC=C)C21C(=O)Nc3ccccc32)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M15 compound treatment 704488.0 121000.0 0.54 740522.0 143000.0 0.71 0.8836 0.9916 1975503 ChemDiv1_011191 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)[N+](=O)[O-])c4ccc(Br)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M16 compound treatment 732899.0 150000.0 0.67 747058.0 149000.0 0.74 0.9964 0.9988 1975504 ChemDiv1_011192 CC(C)OC(=O)C1=C(C)OC(=C(C#N)C1c2cccc(Cl)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M17 compound treatment 759011.0 176000.0 0.79 742367.0 144000.0 0.72 1.0626 0.9988 1593923 ChemDiv1_011193 Cc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M18 compound treatment 722682.0 140000.0 0.62 717304.0 119000.0 0.59 0.8599 0.9996 1975505 ChemDiv1_011194 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)O1)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M19 compound treatment 730662.0 148000.0 0.66 776988.0 179000.0 0.89 1.0942 0.9895 1681847 ChemDiv1_011195 COc1ccc(cc1)c2cc(nc3sc(C(=O)NC4CC4)c(N)c23)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M20 compound treatment 684015.0 101000.0 0.45 759328.0 161000.0 0.8 0.8847 0.9635 1975506 ChemDiv1_011196 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(NC(=O)CCCOc3ccc(Cl)cc3Cl)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M21 compound treatment 747399.0 164000.0 0.74 737923.0 140000.0 0.69 1.0103 0.9996 1975507 ChemDiv1_011197 Nc1nc(SCC(=O)NCc2ccccc2)c(C#N)c(c1C#N)c3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M22 compound treatment 673214.0 90100.0 0.4 729855.0 132000.0 0.65 0.7472 0.9732 1359155 ChemDiv1_011198 O=S(=O)(N1CCC(Cc2ccccc2)CC1)c3cccc4nsnc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M23 mock treatment 660494.0 77400.0 0.35 696493.0 98500.0 0.49 0.5901 0.9859 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 M24 mock treatment 168643.0 -414000.0 -1.86 427496.0 -170000.0 -0.84 -1.909 -0.9365 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N01 compound treatment 588654.0 5560.0 0.02 598194.0 224.0 0.0 0.0184 0.7379 1272054 ChemDiv1_011199 CN(C)c1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N02 compound treatment 664869.0 81800.0 0.37 657424.0 59500.0 0.29 0.4671 0.9942 1527611 ChemDiv1_011200 CCOc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(OC)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N03 compound treatment 786252.0 203000.0 0.91 806043.0 208000.0 1.03 1.3719 0.9981 1463414 ChemDiv1_011201 CN1CCc2nc(SCC(=O)Oc3ccc(C)cc3)c(C#N)c(c4ccco4)c2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N04 compound treatment 668804.0 85700.0 0.38 675633.0 77700.0 0.38 0.5434 1.0 1975508 ChemDiv1_011202 OC1(CC(=NN1C(=O)c2cccc(c2)[N+](=O)[O-])C(F)(F)F)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N05 compound treatment 703532.0 120000.0 0.54 708013.0 110000.0 0.55 0.7667 1.0 1780119 ChemDiv1_011203 [O-][N+](=O)c1cccc(c1)c2csc(NC(=O)c3cc4cc(Br)ccc4oc3=O)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N06 compound treatment 681782.0 98700.0 0.44 658043.0 60100.0 0.3 0.5228 0.9815 1674179 ChemDiv1_011204 Cc1ccccc1C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N07 compound treatment 709936.0 127000.0 0.57 707972.0 110000.0 0.54 0.7868 0.9998 1527151 ChemDiv1_011205 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4cc(OC)c(OC)c(OC)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N08 compound treatment 712447.0 129000.0 0.58 696262.0 98300.0 0.49 0.7538 0.9963 1779828 ChemDiv1_011206 COc1ccc(cc1c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N09 compound treatment 701144.0 118000.0 0.53 728813.0 131000.0 0.65 0.832 0.9949 1523686 ChemDiv1_011207 Cc1c(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c(=O)n(c4ccccc4)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N10 compound treatment 701966.0 119000.0 0.53 710705.0 113000.0 0.56 0.7712 0.9997 1975509 ChemDiv1_011208 COc1cc(Br)c(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N11 compound treatment 725912.0 143000.0 0.64 736452.0 138000.0 0.69 0.9372 0.9994 1561647 ChemDiv1_011209 CC(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N12 compound treatment 655531.0 72400.0 0.32 691442.0 93500.0 0.46 0.5567 0.9848 1975510 ChemDiv1_011210 COc1cc(ccc1Oc2ccc(cc2[N+](=O)[O-])C(F)(F)F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N13 compound treatment 721402.0 138000.0 0.62 743053.0 145000.0 0.72 0.946 0.9972 1975511 ChemDiv1_011211 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N14 compound treatment 690413.0 107000.0 0.48 717945.0 120000.0 0.59 0.76 0.9944 1975512 ChemDiv1_011212 O=C/1N(/C(=N/c2ccccn2)/S\C1=C\c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N15 compound treatment 729369.0 146000.0 0.65 777246.0 179000.0 0.89 1.091 0.9888 1657006 ChemDiv1_011213 CCOC(=O)c1ccc(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N16 compound treatment 716777.0 134000.0 0.6 683288.0 85300.0 0.42 0.722 0.9855 1975513 ChemDiv1_011214 COc1ccc(Nc2nc(Cl)nc(NC(C)C)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N17 compound treatment 760094.0 177000.0 0.79 718624.0 121000.0 0.6 0.9829 0.9903 1202610 ChemDiv1_011215 Clc1cc(Cl)c(cc1C(=O)Oc2cccc3cccnc23)S(=O)(=O)N4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N18 compound treatment 733317.0 150000.0 0.67 759513.0 162000.0 0.8 1.0414 0.9963 1975514 ChemDiv1_011216 CCOC(=O)/C=C(\C)/N1N=C(CC1c2ccccc2)/C=C/c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N19 compound treatment 740049.0 157000.0 0.7 786649.0 189000.0 0.93 1.1577 0.9901 1975515 ChemDiv1_011217 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccccc3C(F)(F)F)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N20 compound treatment 702318.0 119000.0 0.53 749758.0 152000.0 0.75 0.9091 0.9859 1975516 ChemDiv1_011218 Cc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(Cl)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N21 compound treatment 727620.0 145000.0 0.65 736199.0 138000.0 0.68 0.9417 0.9996 1502768 ChemDiv1_011219 Brc1ccc(OCc2ccccc2)c(C=c3sc4nc5ccccc5n4c3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N22 compound treatment 675477.0 92400.0 0.41 731156.0 133000.0 0.66 0.759 0.9747 1975517 ChemDiv1_011220 COC(=O)C1=C(N)N(C2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N23 mock treatment 667596.0 84500.0 0.38 691699.0 93700.0 0.46 0.5958 0.9948 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 N24 mock treatment 414808.0 -168000.0 -0.75 395911.0 -202000.0 -1.0 -1.2404 -0.9902 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O01 compound treatment 571665.0 -11400.0 -0.05 572428.0 -25500.0 -0.13 -0.1256 -0.9206 1975518 ChemDiv1_011221 CC/1=NN(C(=O)\C1=C/Nc2ccc(I)cc2)c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O02 compound treatment 602739.0 19600.0 0.09 614051.0 16100.0 0.08 0.1185 0.9988 1975519 ChemDiv1_011222 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O03 compound treatment 652296.0 69200.0 0.31 648451.0 50500.0 0.25 0.3959 0.9944 1975520 ChemDiv1_011223 COc1ccc(N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccccc3)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O04 compound treatment 625667.0 42600.0 0.19 633980.0 36000.0 0.18 0.2609 0.9995 1975521 ChemDiv1_011224 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O05 compound treatment 659023.0 75900.0 0.34 680853.0 82900.0 0.41 0.5307 0.9956 1294636 ChemDiv1_011225 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4OCc5ccc(Cl)cc5)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O06 compound treatment 633385.0 50300.0 0.23 630780.0 32800.0 0.16 0.2741 0.9872 1975522 ChemDiv1_011226 Oc1ccccc1C2(O)CC(=NN2C(=O)c3ccccc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O07 compound treatment 651956.0 68900.0 0.31 659221.0 61300.0 0.3 0.4325 1.0 1975523 ChemDiv1_011227 O=S1(=O)N=C(N(CCOc2ccccc2)CCOc3ccccc3)c4ccccc41 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O08 compound treatment 635266.0 52200.0 0.23 662403.0 64400.0 0.32 0.3909 0.9882 1975524 ChemDiv1_011228 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccc(c3)[N+](=O)[O-])N)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O09 compound treatment 632753.0 49700.0 0.22 675652.0 77700.0 0.38 0.4293 0.966 1298980 ChemDiv1_011229 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(C)c4ccc(OC)c(c14)S(=O)(=O)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O10 compound treatment 650449.0 67400.0 0.3 668364.0 70400.0 0.35 0.4598 0.9974 1975525 ChemDiv1_011230 Cc1cc(ccc1[N+](=O)[O-])c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O11 compound treatment 746439.0 163000.0 0.73 756347.0 158000.0 0.78 1.0718 0.9994 1975526 ChemDiv1_011231 Cc1cccc(NC(=O)c2sc3nc(cc(c3c2N)C(F)(F)F)c4cccs4)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O12 compound treatment 3459221.0 2880000.0 12.87 2848656.0 2250000.0 11.15 16.9876 0.9974 1718948 ChemDiv1_011232 CC(=O)OCc1cc(C2C(=C(N)OC(=C2C#N)N)C#N)c(C)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O13 compound treatment 646973.0 63900.0 0.29 710077.0 112000.0 0.56 0.5949 0.9524 1268230 ChemDiv1_011233 CCOC(=O)C1=C(C)NC(=O)NC1c2c(OCC(=O)N3CCCCC3)ccc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O14 compound treatment 642004.0 58900.0 0.26 671775.0 73800.0 0.37 0.445 0.9871 1975527 ChemDiv1_011234 CC1=C(C(=O)OCc2ccccc2)C3(C(=O)Nc4ccccc43)C(=C(N)O1)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O15 compound treatment 662380.0 79300.0 0.35 700178.0 102000.0 0.51 0.609 0.9849 1975528 ChemDiv1_011235 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O16 compound treatment 687912.0 105000.0 0.47 693325.0 95400.0 0.47 0.6658 1.0 1975529 ChemDiv1_011236 CC1=C(C(C(=C(N)O1)C#N)c2cccc(Cl)c2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O17 compound treatment 704684.0 122000.0 0.54 708559.0 111000.0 0.55 0.7723 1.0 1125614 ChemDiv1_011237 CCOC(=O)C1=C(C)NC(=O)NC1c2c(OCC(=O)N3CCOCC3)ccc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O18 compound treatment 663665.0 80600.0 0.36 697853.0 99900.0 0.49 0.6049 0.9879 1531706 ChemDiv1_011238 COCC1=C(C#N)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O19 compound treatment 693365.0 110000.0 0.49 716442.0 118000.0 0.59 0.764 0.9963 1337800 ChemDiv1_011239 COc1ccc(cc1)c2cc(nc(SCC(=O)NC3CC3)c2C#N)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O20 compound treatment 658447.0 75400.0 0.34 690739.0 92800.0 0.46 0.5635 0.9884 1975530 ChemDiv1_011240 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3cccc(c3)C(F)(F)F)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O21 compound treatment 686722.0 104000.0 0.46 704884.0 107000.0 0.53 0.7025 0.9978 1975531 ChemDiv1_011241 Clc1ccc(Nc2nc(Cl)nc(n2)N3CCOCC3)nc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O22 compound treatment 639888.0 56800.0 0.25 663483.0 65500.0 0.32 0.4093 0.9927 1975532 ChemDiv1_011242 CCOC(=O)c1c(CSc2nc(C)c(C/C=C/C)c(C)c2C#N)n(C)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O23 mock treatment 633007.0 49900.0 0.22 643859.0 45900.0 0.23 0.3187 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 O24 mock treatment 418859.0 -164000.0 -0.74 426721.0 -171000.0 -0.85 -1.1197 -0.9975 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P01 compound treatment 589810.0 6720.0 0.03 603134.0 5160.0 0.03 0.0394 0.9968 1975533 ChemDiv1_011243 COCC1=C(C(C(=C(N)O1)C#N)c2ccc(F)c(Br)c2)C(=O)OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P02 compound treatment 567499.0 -15600.0 -0.07 585759.0 -12200.0 -0.06 -0.0921 -0.9975 1975534 ChemDiv1_011244 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(Br)cc3)C(=O)CCC2)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P03 compound treatment 588783.0 5690.0 0.03 606498.0 8530.0 0.04 0.0479 0.9707 1975535 ChemDiv1_011245 CCOC(=O)C1=C(OC(=C(C#N)C1c2cccc(Br)c2)N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P04 compound treatment 582678.0 -412.0 0.0 623701.0 25700.0 0.13 0.0888 0.6968 1975536 ChemDiv1_011246 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(Br)s4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P05 compound treatment 589254.0 6160.0 0.03 612489.0 14500.0 0.07 0.0704 0.9135 1285709 ChemDiv1_011247 CC(C)OC(=O)COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P06 compound treatment 588891.0 5800.0 0.03 642141.0 44200.0 0.22 0.1731 0.7855 1975537 ChemDiv1_011248 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccccn3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P07 compound treatment 909263.0 326000.0 1.46 894046.0 296000.0 1.47 2.0695 1.0 1975538 ChemDiv1_011249 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cn3)c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P08 compound treatment 613240.0 30100.0 0.13 614048.0 16100.0 0.08 0.1518 0.9684 1490369 ChemDiv1_011250 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P09 compound treatment 621865.0 38800.0 0.17 626504.0 28500.0 0.14 0.2227 0.9948 1975539 ChemDiv1_011251 CCOC(=O)C1(O)CC(=NN1C(=O)c2cccc(Br)c2)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P10 compound treatment 610497.0 27400.0 0.12 637074.0 39100.0 0.19 0.2237 0.9757 1614784 ChemDiv1_011252 CSc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P11 compound treatment 611568.0 28500.0 0.13 619696.0 21700.0 0.11 0.1662 0.9965 1975540 ChemDiv1_011253 [O-][N+](=O)c1ccc(N/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccc(cc3)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P12 compound treatment 630357.0 47300.0 0.21 641317.0 43300.0 0.21 0.3015 1.0 1303258 ChemDiv1_011254 Cc1ccc(cc1Cl)c2ccc(o2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P13 compound treatment 619421.0 36300.0 0.16 642419.0 44400.0 0.22 0.2707 0.9889 1367677 ChemDiv1_011255 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)cc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P14 compound treatment 633647.0 50600.0 0.23 640815.0 42800.0 0.21 0.3101 0.9995 1975541 ChemDiv1_011256 COc1cccc(c1)C2(O)CC(=NN2C(=O)c3ccc(cc3)C(C)(C)C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P15 compound treatment 618033.0 34900.0 0.16 642667.0 44700.0 0.22 0.2672 0.9855 1975542 ChemDiv1_011257 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P16 compound treatment 647915.0 64800.0 0.29 643413.0 45400.0 0.23 0.3644 0.9921 1975543 ChemDiv1_011258 OC1(CC(=NN1C(=O)c2ccc(cc2)[N+](=O)[O-])C(F)(F)F)c3ccncc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P17 compound treatment 651384.0 68300.0 0.31 652591.0 54600.0 0.27 0.4075 0.9981 1975544 ChemDiv1_011259 COc1ccc(cc1)C2=NN(C(C2)c3ccco3)c4nc(cs4)c5ccc(cc5)S(=O)(=O)N6CCOCC6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P18 compound treatment 727890.0 145000.0 0.65 727258.0 129000.0 0.64 0.9112 1.0 1658665 ChemDiv1_011260 CCOC(=O)C1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P19 compound treatment 643486.0 60400.0 0.27 670272.0 72300.0 0.36 0.4444 0.9904 1210411 ChemDiv1_011261 COc1cc(cc(OC)c1OC)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(F)cc4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P20 compound treatment 714272.0 131000.0 0.59 733200.0 135000.0 0.67 0.8889 0.9978 1975545 ChemDiv1_011262 Cc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccc(Br)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P21 compound treatment 687050.0 104000.0 0.47 730724.0 133000.0 0.66 0.7941 0.9857 1975546 ChemDiv1_011263 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(F)cc3)c4ccc(Br)s4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P22 compound treatment 617478.0 34400.0 0.15 630455.0 32500.0 0.16 0.2226 0.9998 1975547 ChemDiv1_011264 Brc1ccccc1C(=O)OCCOCCNC2=NS(=O)(=O)c3ccccc23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P23 mock treatment 571919.0 -11200.0 -0.05 629686.0 31700.0 0.16 0.0757 0.4593 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.618 P24 mock treatment 322389.0 -261000.0 -1.17 466534.0 -131000.0 -0.65 -1.2856 -0.962 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A01 compound treatment 573964.0 -2250.0 -0.01 589958.0 3690.0 0.02 0.0058 0.2784 1220224 ChemDiv1_011265 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A02 compound treatment 584011.0 7800.0 0.03 581260.0 -5010.0 -0.02 0.0071 0.1667 1975548 ChemDiv1_011266 CCN(CC)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CCC3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A03 compound treatment 601420.0 25200.0 0.11 589096.0 2830.0 0.01 0.0897 0.7888 1680030 ChemDiv1_011267 Fc1ccc2[nH]c3nc4ncc(Br)cc4nc3c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A04 compound treatment 572805.0 -3410.0 -0.02 593105.0 6840.0 0.03 0.0132 0.3544 1975549 ChemDiv1_011268 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)N4CCN(C/C=C/c5ccccc5)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A05 compound treatment 611995.0 35800.0 0.16 641560.0 55300.0 0.27 0.3069 0.9674 1975550 ChemDiv1_011269 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCCOC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A06 compound treatment 612710.0 36500.0 0.16 644978.0 58700.0 0.29 0.3212 0.9628 1693509 ChemDiv1_011270 COc1ccc(Nc2nc(NCc3ccco3)nc(OC)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A07 compound treatment 639456.0 63200.0 0.28 653582.0 67300.0 0.33 0.436 0.9967 1975551 ChemDiv1_011271 CC(=O)c1sc(nc1C)N2N=C(CC2c3ccco3)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A08 compound treatment 648638.0 72400.0 0.32 665997.0 79700.0 0.39 0.5085 0.9952 1194748 ChemDiv1_011272 O=C(CSc1nc2ccccc2[nH]1)OCC(=O)N3c4ccccc4Sc5ccccc35 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A09 compound treatment 636120.0 59900.0 0.27 650607.0 64300.0 0.32 0.415 0.9963 1975552 ChemDiv1_011273 COC(=O)C1=C(N)N(C2=C(C1c3cccc(c3)[N+](=O)[O-])C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A10 compound treatment 659965.0 83800.0 0.37 684127.0 97900.0 0.48 0.6079 0.9919 1388274 ChemDiv1_011274 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A11 compound treatment 622972.0 46800.0 0.21 652701.0 66400.0 0.33 0.3807 0.9761 1975553 ChemDiv1_011275 CCSc1nc2ccccc2n1CC(=O)Nc3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A12 compound treatment 622350.0 46100.0 0.21 658983.0 72700.0 0.36 0.4007 0.9651 1975554 ChemDiv1_011276 CCCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(C)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A13 compound treatment 620560.0 44300.0 0.2 665878.0 79600.0 0.39 0.4192 0.9495 1715729 ChemDiv1_011277 CCN(CC)S(=O)(=O)c1cc(ccc1C)C(=O)N2CCN(CC2)C(=O)c3ccc(C)c(c3)S(=O)(=O)N(CC)CC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A14 compound treatment 814859.0 239000.0 1.07 857921.0 272000.0 1.35 1.7069 0.9935 1394110 ChemDiv1_011278 CCOC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A15 compound treatment 644892.0 68700.0 0.31 668179.0 81900.0 0.41 0.5043 0.9906 1975555 ChemDiv1_011279 Nc1cnn2C(SCC(=O)Nc3nnc(SCC(=O)Nc4ccccc4)s3)N=Nc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A16 compound treatment 801717.0 226000.0 1.01 813630.0 227000.0 1.13 1.5102 0.9985 1975556 ChemDiv1_011280 COc1ccc2ccccc2c1/C=C/3\S/C(=N\c4ccccc4)/N(N(C)C)C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A17 compound treatment 891757.0 316000.0 1.41 893665.0 307000.0 1.52 2.0756 0.9993 1193154 ChemDiv1_011281 Nc1nc(SCC(=O)N2c3ccccc3Sc4ccccc24)c(C#N)cc1C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A18 compound treatment 661885.0 85700.0 0.38 679367.0 93100.0 0.46 0.5973 0.9958 1400320 ChemDiv1_011282 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccc6C(=O)OCc6c5)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A19 compound treatment 657031.0 80800.0 0.36 667906.0 81600.0 0.4 0.5418 0.9985 1397443 ChemDiv1_011283 CCC(CC)C(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A20 compound treatment 649984.0 73800.0 0.33 643409.0 57100.0 0.28 0.4337 0.9971 1975557 ChemDiv1_011284 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccc(C)cc3)cc(Br)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A21 compound treatment 613915.0 37700.0 0.17 643327.0 57100.0 0.28 0.3192 0.9696 1355599 ChemDiv1_011285 CCOC(=O)c1c(c2ccccc2)n(Cc3ccccc3)c4ccc(OC(=O)C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A22 compound treatment 613224.0 37000.0 0.17 617514.0 31200.0 0.15 0.2266 0.9994 1975558 ChemDiv1_011286 Cc1cccc(/N=C\2/NC(=O)/C(=C/c3c(O)ccc4ccccc34)/S2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A23 mock treatment 587747.0 11500.0 0.05 594270.0 8000.0 0.04 0.0645 0.9915 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 A24 mock treatment 528119.0 -48100.0 -0.22 498936.0 -87300.0 -0.43 -0.4581 -0.9481 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B01 compound treatment 575055.0 -1160.0 -0.01 587107.0 837.0 0.0 -7.0E-4 -0.1096 1975559 ChemDiv1_011287 NC1=C(C#N)C(C(=C(O1)c2ccccc2)Sc3ccc(cc3)[N+](=O)[O-])c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B02 compound treatment 634555.0 58300.0 0.26 617076.0 30800.0 0.15 0.2926 0.9673 1172090 ChemDiv1_011288 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccccc5C(=O)O)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B03 compound treatment 668189.0 92000.0 0.41 675969.0 89700.0 0.44 0.6053 0.9993 1536187 ChemDiv1_011289 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(c4ccccc4)c5cc(Br)c(O)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B04 compound treatment 656749.0 80500.0 0.36 683812.0 97500.0 0.48 0.5966 0.9896 1975560 ChemDiv1_011290 Cc1ccc(/C=C/2\SC(=S)N(CN3CCCC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B05 compound treatment 687045.0 111000.0 0.5 706634.0 120000.0 0.6 0.7724 0.9958 1975561 ChemDiv1_011291 COc1ccc(cc1OC)S(=O)(=O)NCCSc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B06 compound treatment 682810.0 107000.0 0.48 694923.0 109000.0 0.54 0.718 0.9982 1305593 ChemDiv1_011292 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B07 compound treatment 693225.0 117000.0 0.52 727593.0 141000.0 0.7 0.8654 0.9898 1543160 ChemDiv1_011293 Clc1ccc(NC(=O)c2ccccc2NS(=O)(=O)c3cccc4nsnc34)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B08 compound treatment 699356.0 123000.0 0.55 711422.0 125000.0 0.62 0.8282 0.9983 1390051 ChemDiv1_011294 Nc1nnc(SCC(=O)Nc2nnc(SCC(=O)Nc3ccc(Br)cc3)s2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B09 compound treatment 696201.0 120000.0 0.54 727088.0 141000.0 0.7 0.8731 0.9917 1975562 ChemDiv1_011295 CC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B10 compound treatment 673651.0 97400.0 0.44 702676.0 116000.0 0.58 0.7162 0.9905 1975563 ChemDiv1_011296 CCN/1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/S\C1=N/c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B11 compound treatment 710124.0 134000.0 0.6 740459.0 154000.0 0.76 0.964 0.9928 1399348 ChemDiv1_011297 Clc1nc(NCCN2CCOCC2)nc(NCc3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B12 compound treatment 680776.0 105000.0 0.47 707863.0 122000.0 0.6 0.7569 0.9922 1975564 ChemDiv1_011298 O=C/1N(C2CCCCC2)/C(=N\c3ccccc3)/S\C1=C/c4cccnc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B13 compound treatment 811017.0 235000.0 1.05 825429.0 239000.0 1.18 1.581 0.9982 1975565 ChemDiv1_011299 O=C(NN1C(=O)C2C(C3C=CC2C4CC43)C1=O)C5CC5(c6ccccc6)c7ccccc7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B14 compound treatment 1310687.0 734000.0 3.29 1264826.0 679000.0 3.36 4.7017 0.9999 1282326 ChemDiv1_011300 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(O)cc3)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B15 compound treatment 817117.0 241000.0 1.08 863675.0 277000.0 1.37 1.7342 0.9928 1327714 ChemDiv1_011301 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)c4cccc(c4)C(=O)O)c(=O)n2C1c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B16 compound treatment 691154.0 115000.0 0.51 719454.0 133000.0 0.66 0.8304 0.9924 1562546 ChemDiv1_011302 CCOC(=O)c1c(CSc2ccccc2)n(C)c3cc(Br)c(O)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B17 compound treatment 793593.0 217000.0 0.97 793384.0 207000.0 1.03 1.4136 0.9996 1368198 ChemDiv1_011303 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Cl)ccc3O)c(=O)n2C1c4ccc(OC)c(OC)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B18 compound treatment 651599.0 75400.0 0.34 726902.0 141000.0 0.7 0.7312 0.9446 1975566 ChemDiv1_011304 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(o4)c5ccc(cc5)[N+](=O)[O-])c(=O)n23)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B19 compound treatment 715766.0 140000.0 0.62 730784.0 145000.0 0.72 0.9479 0.9977 1445361 ChemDiv1_011305 CCOC(=O)c1c(CSc2nc3ccccc3s2)[nH]c4cc(Br)c(OC(=O)C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B20 compound treatment 681855.0 106000.0 0.47 714383.0 128000.0 0.63 0.7832 0.9895 1975567 ChemDiv1_011306 COCC(CN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B21 compound treatment 715708.0 139000.0 0.62 724805.0 139000.0 0.69 0.9268 0.9989 1664761 ChemDiv1_011307 Fc1ccc(cc1Cl)N2C(Nc3ccccc3C2=O)c4ccc(Cl)cc4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B22 compound treatment 648189.0 72000.0 0.32 687980.0 102000.0 0.5 0.5841 0.9767 1485979 ChemDiv1_011308 CCCC(=O)CN1C(=O)C2(OCCO2)c3ccccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B23 mock treatment 642415.0 66200.0 0.3 681595.0 95300.0 0.47 0.5435 0.9748 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 B24 mock treatment 288187.0 -288000.0 -1.29 492319.0 -94000.0 -0.47 -1.2408 -0.9052 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C01 compound treatment 612776.0 36600.0 0.16 598146.0 11900.0 0.06 0.1573 0.9046 1263377 ChemDiv1_011309 CSc1nc2ccc(NC(=O)CSCC(=O)Nc3ccc4ccccc4c3)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C02 compound treatment 1332575.0 756000.0 3.39 1280199.0 694000.0 3.44 4.8248 1.0 1322568 ChemDiv1_011310 COC(=O)c1c(sc2CCCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C03 compound treatment 681146.0 105000.0 0.47 676514.0 90200.0 0.45 0.6483 0.9997 1253038 ChemDiv1_011311 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C04 compound treatment 1077434.0 501000.0 2.24 1078349.0 492000.0 2.44 3.3102 0.9991 1451992 ChemDiv1_011312 COC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5cccnc5)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C05 compound treatment 696539.0 120000.0 0.54 689248.0 103000.0 0.51 0.7416 0.9996 1975568 ChemDiv1_011313 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C06 compound treatment 692832.0 117000.0 0.52 701956.0 116000.0 0.57 0.7744 0.9989 1499493 ChemDiv1_011314 COc1nc(NCc2cccnc2)nc(n1)N3CCC(C)CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C07 compound treatment 700168.0 124000.0 0.55 713016.0 127000.0 0.63 0.8363 0.9981 1975569 ChemDiv1_011315 O=C1c2ccccc2C(=O)c3cc(ccc13)S(=O)(=O)Nc4nc(cs4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C08 compound treatment 721493.0 145000.0 0.65 746260.0 160000.0 0.79 1.0203 0.9952 1975570 ChemDiv1_011316 [O-][N+](=O)c1ccc(Nc2nc(NCc3ccco3)nc(NCc4ccco4)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C09 compound treatment 882460.0 306000.0 1.37 879474.0 293000.0 1.45 1.9964 0.9996 1633386 ChemDiv1_011317 CCOC(=O)COc1ccc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C10 compound treatment 685946.0 110000.0 0.49 715358.0 129000.0 0.64 0.7995 0.9915 1491955 ChemDiv1_011318 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C11 compound treatment 737995.0 162000.0 0.72 741483.0 155000.0 0.77 1.0558 0.9996 1280895 ChemDiv1_011319 CCOc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C12 compound treatment 731138.0 155000.0 0.69 739216.0 153000.0 0.76 1.0261 0.999 1466729 ChemDiv1_011320 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C13 compound treatment 871097.0 295000.0 1.32 891576.0 305000.0 1.51 2.0028 0.9977 1975571 ChemDiv1_011321 CN(C)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C14 compound treatment 875198.0 299000.0 1.34 877802.0 292000.0 1.44 1.9676 0.9993 1299416 ChemDiv1_011322 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C15 compound treatment 839083.0 263000.0 1.18 860148.0 274000.0 1.36 1.7914 0.9975 1975572 ChemDiv1_011323 CCOC(=O)C1=C(N)OC2=C(C1c3cc(Br)c(C)s3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C16 compound treatment 744745.0 169000.0 0.75 748745.0 162000.0 0.8 1.1026 0.9995 1975573 ChemDiv1_011324 COc1cccc(/C=C/2\SC(=N)NC2=O)c1OCc3ccc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C17 compound treatment 724435.0 148000.0 0.66 763704.0 177000.0 0.88 1.0907 0.9904 1975574 ChemDiv1_011325 CC(C)(C)C1(O)CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C18 compound treatment 713353.0 137000.0 0.61 747277.0 161000.0 0.8 0.9981 0.9916 1975575 ChemDiv1_011326 CC/1=NN(C(=O)\C1=C\c2cn(Cc3ccccc3)c4ccccc24)c5ccc(Cl)c(c5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C19 compound treatment 720556.0 144000.0 0.65 740999.0 155000.0 0.77 0.9989 0.9964 1206196 ChemDiv1_011327 COc1nc(NCCN2CCOCC2)nc(Nc3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C20 compound treatment 673041.0 96800.0 0.43 688850.0 103000.0 0.51 0.6658 0.9969 1333946 ChemDiv1_011328 Cc1cc(C)c(C#N)c(SCC(O)COc2ccc(cc2)C(C)(C)C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C21 compound treatment 744458.0 168000.0 0.75 746664.0 160000.0 0.79 1.0944 0.9996 1632518 ChemDiv1_011329 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCN(CC4)c5ccccc5)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C22 compound treatment 777810.0 202000.0 0.9 788205.0 202000.0 1.0 1.3455 0.9987 1975576 ChemDiv1_011330 CN(C)c1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc5OCOc5cc4Br)c(=O)n23)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C23 mock treatment 686448.0 110000.0 0.49 703630.0 117000.0 0.58 0.76 0.9967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 C24 mock treatment 525292.0 -50900.0 -0.23 521226.0 -65000.0 -0.32 -0.389 -0.9856 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D01 compound treatment 595830.0 19600.0 0.09 585589.0 -681.0 0.0 0.0597 0.6794 1736956 ChemDiv1_011331 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C#N)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D02 compound treatment 609244.0 33000.0 0.15 592454.0 6180.0 0.03 0.1262 0.8359 1975577 ChemDiv1_011332 CN(C)CCCNc1cc2oc3cccc(C)c3[nH]c2c4c(=O)c5ccccc5c(=O)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D03 compound treatment 682916.0 107000.0 0.48 686654.0 100000.0 0.5 0.6894 0.9998 1945518 ChemDiv1_011333 Brc1cccc(c1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D04 compound treatment 653901.0 77700.0 0.35 670752.0 84500.0 0.42 0.5418 0.9958 1975578 ChemDiv1_011334 Cn1c(SCC(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2)nnc1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D05 compound treatment 683642.0 107000.0 0.48 712736.0 126000.0 0.63 0.783 0.9915 1975579 ChemDiv1_011335 CCOc1cc(Br)c(C=C2C(=O)N(C)C(=S)N(C)C2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D06 compound treatment 703528.0 127000.0 0.57 704143.0 118000.0 0.58 0.8159 0.9999 1975580 ChemDiv1_011336 COc1ccc(OC)c(/C=C\2/S\C(=N\c3ccccc3)\N(CC=C)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D07 compound treatment 861553.0 285000.0 1.28 861514.0 275000.0 1.36 1.8673 0.9995 1975581 ChemDiv1_011337 CCOc1ccc2nc(Sc3ccc(C=C4C(=O)NC(=S)NC4=O)o3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D08 compound treatment 735256.0 159000.0 0.71 736142.0 150000.0 0.74 1.0284 0.9998 1975582 ChemDiv1_011338 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCCCCC3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D09 compound treatment 722574.0 146000.0 0.66 759143.0 173000.0 0.86 1.0688 0.9913 1975583 ChemDiv1_011339 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(F)cc2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D10 compound treatment 756015.0 180000.0 0.8 783902.0 198000.0 0.98 1.2614 0.9953 1315404 ChemDiv1_011340 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2Cl)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D11 compound treatment 732515.0 156000.0 0.7 757141.0 171000.0 0.85 1.0933 0.9955 1975584 ChemDiv1_011341 COc1ccc(Nc2nc(Cl)nc(NCC=C)n2)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D12 compound treatment 716032.0 140000.0 0.63 720793.0 135000.0 0.67 0.9138 0.9995 1924594 ChemDiv1_011342 OC(=O)c1cccc(c1)N2C(=O)C3C4C=CC(C3C2=O)C4=C(c5ccccc5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D13 compound treatment 823329.0 247000.0 1.11 838724.0 252000.0 1.25 1.6665 0.9981 1371037 ChemDiv1_011343 CCOC(=O)CC1=C(C(C(=C(N)O1)C#N)c2ccc(C)cc2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D14 compound treatment 1068012.0 492000.0 2.2 933103.0 347000.0 1.72 2.7716 0.9925 1199808 ChemDiv1_011344 CCOC(=O)c1c(CN2CCCCC2)n(C3CCCCC3)c4cc(Br)c(O)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D15 compound treatment 808685.0 232000.0 1.04 811959.0 226000.0 1.12 1.5264 0.9994 1850655 ChemDiv1_011345 CCOc1ccc(/C=C/2\CN(C)CC3=C2OC(=C(C#N)C3c4ccc(OCC)cc4)N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D16 compound treatment 745263.0 169000.0 0.76 805150.0 219000.0 1.08 1.3018 0.9845 1133667 ChemDiv1_011346 CCOC(=O)c1c(CS(=O)(=O)c2ccccc2)n(C)c3cc(Br)c(O)c(CN(C)C)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D17 compound treatment 3190922.0 2610000.0 11.7 3162784.0 2580000.0 12.76 17.3015 0.9991 1339490 ChemDiv1_011347 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)cc3Br)c(=O)n2C1c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D18 compound treatment 670244.0 94000.0 0.42 734489.0 148000.0 0.73 0.8168 0.9651 1975585 ChemDiv1_011348 COc1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4cc5OCOc5cc4Br)c(=O)n23)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D19 compound treatment 725803.0 150000.0 0.67 763323.0 177000.0 0.88 1.0937 0.9911 1975586 ChemDiv1_011349 FC(F)(F)c1cccc(c1)n2c(CSCC(=O)Nc3ccccc3)nc4ccccc4c2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D20 compound treatment 713828.0 138000.0 0.62 735805.0 150000.0 0.74 0.9594 0.9958 1975587 ChemDiv1_011350 Cn1c(SCc2c[nH]c3cc(ccc23)[N+](=O)[O-])nc4sc5CCCCc5c4c1=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D21 compound treatment 749635.0 173000.0 0.78 747347.0 161000.0 0.8 1.1132 0.9999 1975588 ChemDiv1_011351 [O-][N+](=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4F)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D22 compound treatment 670486.0 94300.0 0.42 714330.0 128000.0 0.63 0.747 0.9804 1298641 ChemDiv1_011352 CC1CCN(CC1)c2nc(Cl)nc(Nc3ccc4OCOc4c3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D23 mock treatment 657151.0 80900.0 0.36 705055.0 119000.0 0.59 0.6723 0.9729 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 D24 mock treatment 501396.0 -74800.0 -0.33 487022.0 -99200.0 -0.49 -0.5845 -0.9825 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E01 compound treatment 619819.0 43600.0 0.2 610465.0 24200.0 0.12 0.2228 0.9726 1780809 ChemDiv1_011353 [O-][N+](=O)c1ccc(Oc2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E02 compound treatment 643576.0 67400.0 0.3 654979.0 68700.0 0.34 0.4539 0.9982 1449430 ChemDiv1_011354 CC1=C(C(NC(=O)N1)c2cccc(Br)c2)C(=O)OC3CCCCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E03 compound treatment 694698.0 118000.0 0.53 702697.0 116000.0 0.58 0.7829 0.9991 1564780 ChemDiv1_011355 C1CCC(CC1)Nc2nc3nonc3nc2NC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E04 compound treatment 641654.0 65400.0 0.29 666701.0 80400.0 0.4 0.4889 0.9886 1975589 ChemDiv1_011356 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E05 compound treatment 695424.0 119000.0 0.53 706997.0 121000.0 0.6 0.8002 0.9984 1393454 ChemDiv1_011357 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E06 compound treatment 700284.0 124000.0 0.56 719685.0 133000.0 0.66 0.8601 0.9963 1975590 ChemDiv1_011358 Clc1nc(NCc2cccnc2)nc(Nc3ccccc3)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E07 compound treatment 711953.0 136000.0 0.61 731372.0 145000.0 0.72 0.9379 0.9965 1393662 ChemDiv1_011359 Clc1cccc(Nc2nc3nonc3nc2N4CCCCC4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E08 compound treatment 732472.0 156000.0 0.7 735749.0 149000.0 0.74 1.0182 0.9996 1938298 ChemDiv1_011360 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(OC)c(OC)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E09 compound treatment 737183.0 161000.0 0.72 750760.0 164000.0 0.81 1.0857 0.9981 1276030 ChemDiv1_011361 CC1CCN(CC1)c2nc3nonc3nc2Nc4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E10 compound treatment 726464.0 150000.0 0.67 722488.0 136000.0 0.67 0.9527 1.0 1434598 ChemDiv1_011362 Oc1ccc(Nc2nc(Nc3ccc(O)cc3)nc(n2)N4CCOCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E11 compound treatment 813437.0 237000.0 1.06 833422.0 247000.0 1.22 1.6166 0.9975 1197853 ChemDiv1_011363 CC(C)(C)c1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E12 compound treatment 663104.0 86900.0 0.39 719733.0 133000.0 0.66 0.7425 0.968 1975591 ChemDiv1_011364 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)c(c3)[N+](=O)[O-])c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E13 compound treatment 834834.0 259000.0 1.16 856908.0 271000.0 1.34 1.7666 0.9973 1975592 ChemDiv1_011365 CN(C)c1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cccc(c4)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E14 compound treatment 896655.0 320000.0 1.43 965139.0 379000.0 1.88 2.3414 0.9912 1975593 ChemDiv1_011366 COc1ccc(OC)c(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E15 compound treatment 803158.0 227000.0 1.02 837894.0 252000.0 1.25 1.5998 0.9948 1209581 ChemDiv1_011367 CCC1=NN(C(=O)c2ccccc2C)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E16 compound treatment 842261.0 266000.0 1.19 881612.0 295000.0 1.46 1.8767 0.9948 1975594 ChemDiv1_011368 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)cc1Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E17 compound treatment 751907.0 176000.0 0.79 780313.0 194000.0 0.96 1.2358 0.995 1625882 ChemDiv1_011369 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E18 compound treatment 712873.0 137000.0 0.61 771379.0 185000.0 0.92 1.081 0.9806 1975595 ChemDiv1_011370 CC/1=NN(C(=O)\C1=C/c2cc([N+](=O)[O-])c(cc2N3CCOCC3)N4CCOCC4)c5ccc(Cl)c(c5)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E19 compound treatment 736744.0 161000.0 0.72 747411.0 161000.0 0.8 1.0726 0.9986 1975596 ChemDiv1_011371 COC(=O)c1nnn(c1CSc2nc3ccccc3s2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E20 compound treatment 737899.0 162000.0 0.72 755132.0 169000.0 0.84 1.1033 0.9974 1975597 ChemDiv1_011372 [O-][N+](=O)c1ccc(cc1)C(=O)Oc2ccccc2/C=C/3\N=C(OC3=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E21 compound treatment 743620.0 167000.0 0.75 738747.0 152000.0 0.76 1.064 1.0 1388051 ChemDiv1_011373 Cc1ccc(Nc2nc(Cl)nc(n2)N3CCOCC3)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E22 compound treatment 764994.0 189000.0 0.85 777402.0 191000.0 0.95 1.2671 0.9984 1975598 ChemDiv1_011374 Cc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(o3)c4ccc(cc4)C(=O)O)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E23 mock treatment 701369.0 125000.0 0.56 719723.0 133000.0 0.66 0.8636 0.9966 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 E24 mock treatment 514875.0 -61300.0 -0.27 530232.0 -56000.0 -0.28 -0.3904 -1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F01 compound treatment 602344.0 26100.0 0.12 582671.0 -3600.0 -0.02 0.0701 0.5925 1975599 ChemDiv1_011375 Nc1nc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])c(C#N)c(c1C#N)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F02 compound treatment 652000.0 75800.0 0.34 659154.0 72900.0 0.36 0.4952 0.9995 1975600 ChemDiv1_011376 CC(C)(C)c1ccc2[nH]c3c(cc(NCCO)c4c(=O)c5ccccc5c(=O)c34)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F03 compound treatment 693305.0 117000.0 0.52 678660.0 92400.0 0.46 0.6943 0.9977 1632129 ChemDiv1_011377 CCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F04 compound treatment 660946.0 84700.0 0.38 653055.0 66800.0 0.33 0.5021 0.9977 1975601 ChemDiv1_011378 CCOC(=O)C1=C(N(C)C(=O)NC1c2ccc(OC(F)F)c(OC)c2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F05 compound treatment 687431.0 111000.0 0.5 662562.0 76300.0 0.38 0.6193 0.9908 1649620 ChemDiv1_011379 Brc1ccc2n(CCc3ccccc3)c4nc5ccccc5nc4c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F06 compound treatment 686126.0 110000.0 0.49 688191.0 102000.0 0.5 0.7049 0.9999 1975602 ChemDiv1_011380 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc3cccnc3)OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F07 compound treatment 747915.0 172000.0 0.77 722515.0 136000.0 0.67 1.0207 0.9979 1975603 ChemDiv1_011381 CCSCCOC(=O)C1=C(C)NC(=O)NC1c2cc(Br)c(O)c(OC)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F08 compound treatment 705230.0 129000.0 0.58 664492.0 78200.0 0.39 0.6824 0.9812 1975604 ChemDiv1_011382 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)N3CCN(CC3)C(=O)c4ccccc4)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F09 compound treatment 717998.0 142000.0 0.63 734433.0 148000.0 0.73 0.9678 0.9974 1258308 ChemDiv1_011383 CCCC1=C(C(C(=C(N)O1)C#N)c2cccc(F)c2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F10 compound treatment 761065.0 185000.0 0.83 758206.0 172000.0 0.85 1.1874 0.9999 1975605 ChemDiv1_011384 CC1=C(C(C(=C(N)O1)C#N)c2cccs2)C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F11 compound treatment 751193.0 175000.0 0.78 761528.0 175000.0 0.87 1.1678 0.9987 1564790 ChemDiv1_011385 Cc1ccc(NC(=O)CSc2nnc(NC(=O)CSc3nnc4n(N)cnn34)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F12 compound treatment 763384.0 187000.0 0.84 798955.0 213000.0 1.05 1.3375 0.9936 1174585 ChemDiv1_011386 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5ccc(OC)cc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F13 compound treatment 1319470.0 743000.0 3.33 1177028.0 591000.0 2.93 4.422 0.998 1975606 ChemDiv1_011387 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3ccccc3C(=O)O)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F14 compound treatment 793991.0 218000.0 0.97 764109.0 178000.0 0.88 1.3123 0.9987 1709162 ChemDiv1_011388 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(C#Cc5ccccc5)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F15 compound treatment 825295.0 249000.0 1.11 838076.0 252000.0 1.25 1.6705 0.9984 1975607 ChemDiv1_011389 Cc1ccc(C#N)c(SCC(=O)c2ccc(cc2)C(=O)CSc3nc(C)ccc3C#N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F16 compound treatment 749799.0 174000.0 0.78 758302.0 172000.0 0.85 1.1521 0.9989 1975608 ChemDiv1_011390 CCOC(=O)c1c(CNC(=O)C)n(CCBr)c2cc(Br)c(OC)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F17 compound treatment 1843948.0 1270000.0 5.67 1937017.0 1350000.0 6.69 8.7442 0.9966 1975609 ChemDiv1_011391 COc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(OC)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F18 compound treatment 797825.0 222000.0 0.99 816805.0 231000.0 1.14 1.509 0.9975 1975610 ChemDiv1_011392 CCOc1ccccc1NC(=O)CSc2nc(N)c(C#N)cc2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F19 compound treatment 747261.0 171000.0 0.77 729458.0 143000.0 0.71 1.043 0.9993 1149538 ChemDiv1_011393 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(C)c4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F20 compound treatment 722390.0 146000.0 0.65 740396.0 154000.0 0.76 1.0026 0.997 1358934 ChemDiv1_011394 Clc1ccc(C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F21 compound treatment 741997.0 166000.0 0.74 757623.0 171000.0 0.85 1.125 0.9978 1975611 ChemDiv1_011395 CCCCOc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(F)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F22 compound treatment 725923.0 150000.0 0.67 708637.0 122000.0 0.61 0.9025 0.9987 1372308 ChemDiv1_011396 COc1ccc2C3CC(=NN3C(=O)c2c1OC)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F23 mock treatment 690946.0 115000.0 0.51 710966.0 125000.0 0.62 0.8 0.9958 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 F24 mock treatment 509750.0 -66500.0 -0.3 497250.0 -89000.0 -0.44 -0.5222 -0.9816 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G01 compound treatment 613182.0 37000.0 0.17 617158.0 30900.0 0.15 0.2252 0.9992 1780808 ChemDiv1_011397 [O-][N+](=O)c1cc(Cl)ccc1c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G02 compound treatment 629246.0 53000.0 0.24 628230.0 42000.0 0.21 0.3149 0.9978 1323386 ChemDiv1_011398 CCC1=NN(C(=O)c2ccccc2OC)C(O)(C1)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G03 compound treatment 699803.0 124000.0 0.55 681190.0 94900.0 0.47 0.7237 0.9967 1442382 ChemDiv1_011399 Cc1ccc2NC(=O)C3(C(=C(N)OC4=C3C(=O)CCC4)C#N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G04 compound treatment 687280.0 111000.0 0.5 684699.0 98400.0 0.49 0.6963 1.0 1637247 ChemDiv1_011400 CCOC(=O)C1(O)CC(=NN1C(=O)c2ccc(cc2)c3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G05 compound treatment 715490.0 139000.0 0.62 711333.0 125000.0 0.62 0.8789 1.0 1646662 ChemDiv1_011401 COc1ccc(OC)c(c1)N(CC(=O)Nc2cccc(Cl)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G06 compound treatment 694793.0 119000.0 0.53 684088.0 97800.0 0.48 0.718 0.999 1975612 ChemDiv1_011402 COC(=O)c1ccc(/C=C/2\C(=O)N(N=C2c3ccccc3)c4ccc(cc4)[N+](=O)[O-])cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G07 compound treatment 683100.0 107000.0 0.48 711218.0 125000.0 0.62 0.776 0.9919 1975613 ChemDiv1_011403 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(C)s3)C(=O)CCC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G08 compound treatment 738362.0 162000.0 0.73 718041.0 132000.0 0.65 0.9748 0.9986 1975614 ChemDiv1_011404 CC(=O)Oc1ccc(cc1)N2C(=O)C3C(C4CCC3C=C4)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G09 compound treatment 741540.0 165000.0 0.74 728428.0 142000.0 0.7 1.0213 0.9997 1975615 ChemDiv1_011405 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(Br)cs3)C(=O)CC(C)(C)C2)c4cccc(c4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G10 compound treatment 766379.0 190000.0 0.85 767916.0 182000.0 0.9 1.2382 0.9996 1645983 ChemDiv1_011406 CCOC(=O)c1c(CNC(=O)C)n(CC(=O)OC)c2cc(Br)c(OC)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G11 compound treatment 753105.0 177000.0 0.79 765972.0 180000.0 0.89 1.1894 0.9983 1975616 ChemDiv1_011407 [O-][N+](=O)c1ccccc1C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G12 compound treatment 778524.0 202000.0 0.91 791861.0 206000.0 1.02 1.3605 0.9983 1545587 ChemDiv1_011408 COc1ccccc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G13 compound treatment 785439.0 209000.0 0.94 798228.0 212000.0 1.05 1.4047 0.9984 1975617 ChemDiv1_011409 O=C(CN1CCOCC1)Nc2nnc(SCC(=O)N(c3ccccc3)c4ccccc4)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G14 compound treatment 793142.0 217000.0 0.97 840303.0 254000.0 1.26 1.5765 0.9918 1975618 ChemDiv1_011410 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(OCC(C)C)cc3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G15 compound treatment 814646.0 238000.0 1.07 828689.0 242000.0 1.2 1.6039 0.9983 1638738 ChemDiv1_011411 Nc1nnc(SCC(=O)Nc2ccc(NC(=O)CSc3nnc(N)s3)c(Cl)c2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G16 compound treatment 863226.0 287000.0 1.28 869456.0 283000.0 1.4 1.9004 0.999 1975619 ChemDiv1_011412 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G17 compound treatment 788907.0 213000.0 0.95 815514.0 229000.0 1.14 1.4763 0.9962 1182670 ChemDiv1_011413 CCOC(=O)C1=C(N)N(C2=C(C1c3cc(OC)c(OC)c(OC)c3)C(=O)CCC2)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G18 compound treatment 728054.0 152000.0 0.68 748676.0 162000.0 0.8 1.0495 0.9965 1938391 ChemDiv1_011414 COc1cc(cc(OC)c1OC)C2NC(=O)NC(=C2C(=O)OCc3ccc4OCOc4c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G19 compound treatment 759579.0 183000.0 0.82 781311.0 195000.0 0.97 1.2636 0.9967 1362381 ChemDiv1_011415 COc1nccnc1NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3cc4ccccc4oc3=O)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G20 compound treatment 686121.0 110000.0 0.49 782395.0 196000.0 0.97 1.0349 0.9503 1569847 ChemDiv1_011416 CCOC(=O)c1c(CSc2nc(CC(C)C)ccc2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G21 compound treatment 726158.0 150000.0 0.67 751931.0 166000.0 0.82 1.0549 0.995 1975620 ChemDiv1_011417 COC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G22 compound treatment 685171.0 109000.0 0.49 734260.0 148000.0 0.73 0.8633 0.9804 1938286 ChemDiv1_011418 Cc1cc2nc3sc(=Cc4ccc(o4)c5cc(ccc5Cl)[N+](=O)[O-])c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G23 mock treatment 694913.0 119000.0 0.53 702569.0 116000.0 0.58 0.7831 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 G24 mock treatment 517616.0 -58600.0 -0.26 533719.0 -52600.0 -0.26 -0.3695 -1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H01 compound treatment 613497.0 37300.0 0.17 566589.0 -19700.0 -0.1 0.0491 0.2539 1975621 ChemDiv1_011419 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc(SCC(=O)N)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H02 compound treatment 752787.0 177000.0 0.79 725312.0 139000.0 0.69 1.046 0.9976 1975622 ChemDiv1_011420 CCOc1cc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)ccc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H03 compound treatment 701532.0 125000.0 0.56 661055.0 74800.0 0.37 0.6586 0.9797 1470787 ChemDiv1_011421 CCOC(=O)c1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccc(OCC(C)C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H04 compound treatment 685965.0 110000.0 0.49 670869.0 84600.0 0.42 0.6437 0.9969 1683538 ChemDiv1_011422 CCSc1nc2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H05 compound treatment 689318.0 113000.0 0.51 679056.0 92800.0 0.46 0.683 0.9988 1453219 ChemDiv1_011423 Fc1ccc(Cn2c3ccc(Br)cc3c4nc5ccccc5nc24)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H06 compound treatment 724099.0 148000.0 0.66 668934.0 82700.0 0.41 0.7577 0.9733 1975623 ChemDiv1_011424 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H07 compound treatment 727587.0 151000.0 0.68 704760.0 118000.0 0.59 0.8942 0.9974 1269081 ChemDiv1_011425 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCOCC4)c5ccccc53 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H08 compound treatment 800719.0 225000.0 1.0 729861.0 144000.0 0.71 1.2136 0.9857 1137492 ChemDiv1_011426 COc1ccc(cc1)C(=O)c2sc3nc(C)c(C(=O)Nc4ccccc4)c(C)c3c2N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H09 compound treatment 768908.0 193000.0 0.86 745304.0 159000.0 0.79 1.167 0.999 1657857 ChemDiv1_011427 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(OC)c(OC)c2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H10 compound treatment 751620.0 175000.0 0.79 713966.0 128000.0 0.63 1.0025 0.9943 1975624 ChemDiv1_011428 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2[N+](=O)[O-])C(=O)OCC=C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H11 compound treatment 732288.0 156000.0 0.7 727395.0 141000.0 0.7 0.9884 1.0 1394913 ChemDiv1_011429 CCOC(=O)c1nnn(c1CSc2nc3ccc(OCC)cc3s2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H12 compound treatment 1166301.0 590000.0 2.64 1286533.0 700000.0 3.47 4.3207 0.991 1944061 ChemDiv1_011430 CCOc1cc(/C=C\2/SC(=N)NC2=O)ccc1OCc3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H13 compound treatment 772961.0 197000.0 0.88 764963.0 179000.0 0.89 1.2487 1.0 1975625 ChemDiv1_011431 CCOC(=O)CSc1nc2ccccc2n1C(=O)OCCCl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H14 compound treatment 757908.0 182000.0 0.81 769527.0 183000.0 0.91 1.217 0.9985 1975626 ChemDiv1_011432 Nc1c(sc2nc(N)c(C#N)c(c3cccs3)c12)C(=O)Nc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H15 compound treatment 825931.0 250000.0 1.12 816701.0 230000.0 1.14 1.5976 0.9999 1310454 ChemDiv1_011433 CCOC(=O)c1c(CSc2nc(C)c(C)c(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H16 compound treatment 742573.0 166000.0 0.74 748570.0 162000.0 0.8 1.0951 0.9993 1975627 ChemDiv1_011434 CCOC(=O)CNCc1c(C(=O)OCC)c2cc(OC)c(Br)cc2n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H17 compound treatment 994424.0 418000.0 1.87 1083386.0 497000.0 2.46 3.0651 0.9908 1975628 ChemDiv1_011435 CC1CCN(CN2C(=O)/C(=C\c3ccc(cc3)C(C)(C)C)/SC2=S)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H18 compound treatment 795411.0 219000.0 0.98 815514.0 229000.0 1.14 1.4968 0.9974 1975629 ChemDiv1_011436 CCOc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H19 compound treatment 940700.0 364000.0 1.63 937564.0 351000.0 1.74 2.3842 0.9995 1975630 ChemDiv1_011437 FC(F)(F)c1cccc(Nc2nc3nonc3nc2Nc4cccc(c4)C(F)(F)F)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H20 compound treatment 735166.0 159000.0 0.71 742036.0 156000.0 0.77 1.0488 0.9992 1545650 ChemDiv1_011438 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc5ccccc5[nH]c4=O)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H21 compound treatment 714642.0 138000.0 0.62 679387.0 93100.0 0.46 0.7643 0.9894 1975631 ChemDiv1_011439 CCCCCCCCCCn1c(CBr)c(C(=O)OCC)c2cc(OC(=O)C)ccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H22 compound treatment 701461.0 125000.0 0.56 702564.0 116000.0 0.58 0.8038 0.9999 1975632 ChemDiv1_011440 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cc(Br)ccc4O)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H23 mock treatment 685843.0 110000.0 0.49 698955.0 113000.0 0.56 0.7417 0.9979 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 H24 mock treatment 509227.0 -67000.0 -0.3 494779.0 -91500.0 -0.45 -0.5325 -0.9799 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I01 compound treatment 607463.0 31300.0 0.14 602152.0 15900.0 0.08 0.1546 0.9629 1975633 ChemDiv1_011441 CCOC(=O)CSc1nc2ccc(cc2s1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I02 compound treatment 642654.0 66400.0 0.3 635969.0 49700.0 0.25 0.3844 0.9956 1975634 ChemDiv1_011442 CCC1=NN(C(=O)c2ccc(Br)cc2)C(O)(C1)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I03 compound treatment 673364.0 97200.0 0.43 698237.0 112000.0 0.55 0.6997 0.9928 1726267 ChemDiv1_011443 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccc(C)cc32)C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I04 compound treatment 647837.0 71600.0 0.32 664786.0 78500.0 0.39 0.5017 0.9954 1975635 ChemDiv1_011444 [O-][N+](=O)c1cccc(c1)C2SCCN2C(=O)c3cc4ccc(Br)cc4oc3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I05 compound treatment 734344.0 158000.0 0.71 714029.0 128000.0 0.63 0.9481 0.9984 1502137 ChemDiv1_011445 Nc1c(sc2nc(N)c(C#N)cc12)C(=O)N(c3ccccc3)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I06 compound treatment 683206.0 107000.0 0.48 631049.0 44800.0 0.22 0.4955 0.9388 1155132 ChemDiv1_011446 CC(=O)Nc1ccc2nc(SCC(=O)c3ccc(Br)cc3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I07 compound treatment 727977.0 152000.0 0.68 704797.0 119000.0 0.59 0.8956 0.9974 1286476 ChemDiv1_011447 CCOC(=O)c1c(CN2CCN(CC2)c3ccccc3)n(c4ccccc4)c5ccc(O)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I08 compound treatment 728907.0 153000.0 0.68 698500.0 112000.0 0.56 0.8765 0.9947 1391952 ChemDiv1_011448 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc(Br)cc3)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I09 compound treatment 708216.0 132000.0 0.59 721494.0 135000.0 0.67 0.8915 0.998 1975636 ChemDiv1_011449 [O-][N+](=O)c1cc([N+](=O)[O-])c(Sc2nc3ccccc3s2)c(c1)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I10 compound treatment 710752.0 135000.0 0.6 715358.0 129000.0 0.64 0.878 0.9996 1635599 ChemDiv1_011450 CC1=C(C(NC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OCc3ccc4OCOc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I11 compound treatment 743580.0 167000.0 0.75 698324.0 112000.0 0.56 0.9223 0.9891 1975637 ChemDiv1_011451 O=C(Nc1cccc2C(=O)c3ccccc3C(=O)c12)C4CC4(c5ccccc5)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I12 compound treatment 673807.0 97600.0 0.44 706205.0 120000.0 0.59 0.729 0.9886 1266105 ChemDiv1_011452 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CCC2)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I13 compound treatment 710308.0 134000.0 0.6 749804.0 164000.0 0.81 0.9973 0.9891 1975638 ChemDiv1_011453 Brc1ccc(cc1)C(=O)Oc2cccc(NC3=NS(=O)(=O)c4ccccc34)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I14 compound treatment 736834.0 161000.0 0.72 778355.0 192000.0 0.95 1.1813 0.9905 1975639 ChemDiv1_011454 COc1ccc(/C=C\2/S/C(=N\c3ccc(C)cc3)/NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I15 compound treatment 763154.0 187000.0 0.84 788019.0 202000.0 1.0 1.2984 0.9961 1927054 ChemDiv1_011455 COc1ccc(cc1)N(CC(=O)Nc2ccc(Cl)cc2C)S(=O)(=O)c3ccc(C)c(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I16 compound treatment 718276.0 142000.0 0.64 740367.0 154000.0 0.76 0.9895 0.9959 1975640 ChemDiv1_011456 COc1ccc2nc(NC(=O)COC(=O)CC(NC(=O)c3ccccc3)c4ccccc4)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I17 compound treatment 748431.0 172000.0 0.77 767745.0 181000.0 0.9 1.1808 0.9971 1286358 ChemDiv1_011457 COC(=O)C1=C(N)N(C2=C(C1c3ccc(Cl)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I18 compound treatment 658632.0 82400.0 0.37 717678.0 131000.0 0.65 0.7212 0.9638 1293122 ChemDiv1_011458 Clc1ccccc1C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I19 compound treatment 701940.0 126000.0 0.56 747463.0 161000.0 0.8 0.9626 0.9853 1395650 ChemDiv1_011459 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4F)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I20 compound treatment 682351.0 106000.0 0.48 765315.0 179000.0 0.89 0.9631 0.9572 1975641 ChemDiv1_011460 Cc1cc(c2c(N)c(sc2n1)C(=O)c3ccc(cc3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I21 compound treatment 736372.0 160000.0 0.72 755138.0 169000.0 0.84 1.0985 0.997 1975642 ChemDiv1_011461 COc1ccc(cc1OC)S(=O)(=O)N(CC(=O)Nc2ccc3OCOc3c2)c4cc(Cl)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I22 compound treatment 735446.0 159000.0 0.71 717177.0 131000.0 0.65 0.9626 0.9989 1951531 ChemDiv1_011462 CN1CCN(CC1)c2ccc(C=c3sc4nc5ccccc5n4c3=O)cc2[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I23 mock treatment 683057.0 107000.0 0.48 677326.0 91100.0 0.45 0.6572 0.9996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 I24 mock treatment 534728.0 -41500.0 -0.19 208665.0 -378000.0 -1.87 -1.454 -0.7735 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J01 compound treatment 657595.0 81400.0 0.36 623037.0 36800.0 0.18 0.3864 0.9487 1975643 ChemDiv1_011463 CC(C)c1c(C#N)c(N)nc2sc(C(=O)c3ccc(cc3)[N+](=O)[O-])c(N)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J02 compound treatment 646049.0 69800.0 0.31 626813.0 40500.0 0.2 0.3631 0.9771 1781824 ChemDiv1_011464 COc1cc([N+](=O)[O-])c(Cl)cc1c2ccc(C=c3sc4nc5ccccc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J03 compound treatment 702676.0 126000.0 0.57 656995.0 70700.0 0.35 0.648 0.9734 1975644 ChemDiv1_011465 Cc1cccc(C)c1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J04 compound treatment 683569.0 107000.0 0.48 647893.0 61600.0 0.31 0.5557 0.976 1567238 ChemDiv1_011466 Nc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)NC5CC5)sc4c3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J05 compound treatment 982685.0 406000.0 1.82 854495.0 268000.0 1.33 2.2262 0.9881 1975645 ChemDiv1_011467 COc1cc(/C=C\2/SC(=N)NC2=O)ccc1OCc3ccccc3F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J06 compound treatment 710020.0 134000.0 0.6 652110.0 65800.0 0.33 0.6542 0.9592 1728083 ChemDiv1_011468 O=C(CCc1ccccc1)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J07 compound treatment 716835.0 141000.0 0.63 693484.0 107000.0 0.53 0.8207 0.9964 1975646 ChemDiv1_011469 Cc1nn2c(c1[N+](=O)[O-])n3nc(C)c([N+](=O)[O-])c3n4nc(C)c([N+](=O)[O-])c24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J08 compound treatment 832544.0 256000.0 1.15 783061.0 197000.0 0.97 1.5007 0.9967 1975647 ChemDiv1_011470 CCCCOc1ccc(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J09 compound treatment 741226.0 165000.0 0.74 697218.0 111000.0 0.55 0.911 0.9894 1975648 ChemDiv1_011471 CCCC1=C(C(C(=C(N)O1)C#N)c2cccc(c2)[N+](=O)[O-])C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J10 compound treatment 726071.0 150000.0 0.67 747260.0 161000.0 0.8 1.0383 0.9963 1382897 ChemDiv1_011472 CCOC(=O)c1c2CN(CCn2c3cc(Br)c(OC)cc13)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J11 compound treatment 720314.0 144000.0 0.65 629484.0 43200.0 0.21 0.6075 0.8938 1975649 ChemDiv1_011473 CCN/1C(=O)/C(=C\2/C=Cc3ccccc3N2CC)/S\C1=N/c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J12 compound treatment 714976.0 139000.0 0.62 706040.0 120000.0 0.59 0.8588 0.9997 1165690 ChemDiv1_011474 Cc1cccc(c1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J13 compound treatment 759615.0 183000.0 0.82 764387.0 178000.0 0.88 1.2044 0.9994 1139419 ChemDiv1_011475 CCOC(=O)CSc1nc2ccccc2n1C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J14 compound treatment 763752.0 188000.0 0.84 736142.0 150000.0 0.74 1.1186 0.9981 1975650 ChemDiv1_011476 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc3cc(OC)ccc3oc2=O)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J15 compound treatment 759765.0 184000.0 0.82 742013.0 156000.0 0.77 1.1265 0.9995 1533064 ChemDiv1_011477 CCOC(=O)c1c(CSc2nc(C)cc(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J16 compound treatment 762810.0 187000.0 0.84 746520.0 160000.0 0.79 1.152 0.9997 1261676 ChemDiv1_011478 CCOC(=O)c1c(CSc2nc3ccccc3s2)n(c4ccccc4)c5cc(Br)c(OC(=O)C)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J17 compound treatment 743465.0 167000.0 0.75 750054.0 164000.0 0.81 1.1031 0.9992 1975651 ChemDiv1_011479 Fc1ccc(N/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccccc3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J18 compound treatment 766580.0 190000.0 0.85 763305.0 177000.0 0.88 1.2227 0.9999 1618230 ChemDiv1_011480 CC1=C(C(C(=C(N)O1)C#N)c2ccccc2)n3nnc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J19 compound treatment 827432.0 251000.0 1.12 795949.0 210000.0 1.04 1.5297 0.9992 1975652 ChemDiv1_011481 Cc1ccc(Sc2c(F)c3C(=O)c4ccccc4C(=O)c3c(F)c2Sc5ccc(C)cc5)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J20 compound treatment 756779.0 181000.0 0.81 748710.0 162000.0 0.8 1.1406 1.0 1579664 ChemDiv1_011482 CCOc1cc(cc(Cl)c1O)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J21 compound treatment 777326.0 201000.0 0.9 751844.0 166000.0 0.82 1.2166 0.9989 1631566 ChemDiv1_011483 CCOC(=O)c1c(CN2CCCCC2)n(C)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J22 compound treatment 739494.0 163000.0 0.73 703240.0 117000.0 0.58 0.9266 0.9934 1975653 ChemDiv1_011484 COc1ccccc1C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J23 mock treatment 703866.0 128000.0 0.57 706267.0 120000.0 0.59 0.8244 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 J24 mock treatment 519312.0 -56900.0 -0.25 503291.0 -83000.0 -0.41 -0.4708 -0.9735 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K01 compound treatment 594524.0 18300.0 0.08 583284.0 -2990.0 -0.01 0.0475 0.5703 1723745 ChemDiv1_011485 CSc1nc2ccc(NC(=O)CSc3nc4ccccc4[nH]3)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K02 compound treatment 639226.0 63000.0 0.28 623319.0 37000.0 0.18 0.3292 0.9783 1168551 ChemDiv1_011486 COc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(cc4)N(C)C)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K03 compound treatment 659078.0 82900.0 0.37 626952.0 40700.0 0.2 0.4048 0.9589 1975654 ChemDiv1_011487 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)C(c23)c4ccccc4)N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K04 compound treatment 648777.0 72600.0 0.32 614889.0 28600.0 0.14 0.3299 0.9309 1975655 ChemDiv1_011488 CCOC(=O)c1c(CNCCN(CC)CC)n(c2ccccc2)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K05 compound treatment 737409.0 161000.0 0.72 673868.0 87600.0 0.43 0.8171 0.9704 1728996 ChemDiv1_011489 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3sc4CCCCCc4c3C#N)c5cccnc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K06 compound treatment 735969.0 160000.0 0.72 690615.0 104000.0 0.52 0.8712 0.9873 1502978 ChemDiv1_011490 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K07 compound treatment 745090.0 169000.0 0.76 700198.0 114000.0 0.56 0.9336 0.9896 1975656 ChemDiv1_011491 COc1ccc(Nc2nc(Cl)nc(NCc3cccnc3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K08 compound treatment 2974863.0 2400000.0 10.74 2798004.0 2210000.0 10.96 15.3398 0.9999 1975657 ChemDiv1_011492 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(cc3)N(C)C)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K09 compound treatment 744331.0 168000.0 0.75 720524.0 134000.0 0.67 1.0024 0.9981 1181229 ChemDiv1_011493 COc1ccc(Cl)cc1NC(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K10 compound treatment 734260.0 158000.0 0.71 733129.0 147000.0 0.73 1.0147 0.9999 1585280 ChemDiv1_011494 Brc1ccc(cc1)C(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K11 compound treatment 732103.0 156000.0 0.7 723691.0 137000.0 0.68 0.9748 0.9999 1923662 ChemDiv1_011495 COc1ccc(OC)c(c1)N(CC(=O)NCCc2ccc(OC)c(OC)c2)S(=O)(=O)c3ccc(OC)c(OC)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K12 compound treatment 666821.0 90600.0 0.41 676594.0 90300.0 0.45 0.6032 0.9988 1273297 ChemDiv1_011496 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)c(OC)c3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K13 compound treatment 735749.0 160000.0 0.71 706852.0 121000.0 0.6 0.9274 0.9961 1975658 ChemDiv1_011497 CCSc1nnc(NC(=O)COC(=O)CC(NC(=O)c2ccccc2)c3cccc(OC)c3)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K14 compound treatment 802383.0 226000.0 1.01 783360.0 197000.0 0.98 1.4063 0.9998 1975659 ChemDiv1_011498 COc1ccc(/N=C\2/NC(=O)/C(=C/c3c(OC)ccc4ccccc34)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K15 compound treatment 798618.0 222000.0 1.0 772169.0 186000.0 0.92 1.3552 0.9992 1576345 ChemDiv1_011499 CCC1=NN(C(=O)c2ccccc2O)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K16 compound treatment 739755.0 164000.0 0.73 709466.0 123000.0 0.61 0.9492 0.9959 1466228 ChemDiv1_011500 Nc1nnc(SCC(=O)Nc2nnc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)s2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K17 compound treatment 822887.0 247000.0 1.1 813163.0 227000.0 1.12 1.5756 1.0 1734890 ChemDiv1_011501 CCC1=NN(C(=O)c2cccc(Cl)c2)C(O)(C1)c3ccc(OC)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K18 compound treatment 847864.0 272000.0 1.22 808651.0 222000.0 1.1 1.6388 0.9988 1154133 ChemDiv1_011502 COc1ccc(cc1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K19 compound treatment 734271.0 158000.0 0.71 686693.0 100000.0 0.5 0.8521 0.9851 1975660 ChemDiv1_011503 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccccc5C4=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K20 compound treatment 924999.0 349000.0 1.56 871121.0 285000.0 1.41 2.1018 0.9987 1930145 ChemDiv1_011504 COc1ccc(N(CC(=O)NCCSc2nc3ccccc3s2)S(=O)(=O)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K21 compound treatment 737211.0 161000.0 0.72 712216.0 126000.0 0.62 0.9508 0.9974 1975661 ChemDiv1_011505 Cc1ccc(cc1C)N2C(=O)/C(=C/c3cc(Br)ccc3O)/C(=O)NC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K22 compound treatment 728103.0 152000.0 0.68 711569.0 125000.0 0.62 0.9197 0.999 1975662 ChemDiv1_011506 CN(C)c1ccc(cc1)C2C(=C(C)N=c3sc(=Cc4ccc(o4)c5ccc(cc5)[N+](=O)[O-])c(=O)n23)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K23 mock treatment 658812.0 82600.0 0.37 701711.0 115000.0 0.57 0.6658 0.9777 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 K24 mock treatment 380239.0 -196000.0 -0.88 508085.0 -78200.0 -0.39 -0.8942 -0.9325 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L01 compound treatment 602483.0 26300.0 0.12 601716.0 15400.0 0.08 0.1373 0.9783 1785091 ChemDiv1_011507 Cc1ccc(cc1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Oc4ccccc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L02 compound treatment 672491.0 96300.0 0.43 630632.0 44400.0 0.22 0.4601 0.9511 1975663 ChemDiv1_011508 CCOC(=O)c1c(CSc2nc(C)cc(c2C#N)C(F)(F)F)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L03 compound treatment 719336.0 143000.0 0.64 657608.0 71300.0 0.35 0.7029 0.9607 1975664 ChemDiv1_011509 CCOC(=O)C1=C(C)NC(=O)NC1c2ccc(OS(=O)(=O)c3ccc(C)cc3)cc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L04 compound treatment 698951.0 123000.0 0.55 646235.0 60000.0 0.3 0.5986 0.9583 1975665 ChemDiv1_011510 CCCCNC(=O)CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L05 compound treatment 718677.0 142000.0 0.64 658686.0 72400.0 0.36 0.7046 0.963 1975666 ChemDiv1_011511 CCOc1cc(/C=C/2\C(=O)N(N=C2c3ccccc3)c4ccc(cc4)[N+](=O)[O-])ccc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L06 compound treatment 688270.0 112000.0 0.5 666448.0 80200.0 0.4 0.6356 0.9933 1975667 ChemDiv1_011512 CCOC(=O)c1nnn(c1CSc2nc3cc(OC)ccc3[nH]2)c4nonc4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L07 compound treatment 755641.0 179000.0 0.8 699127.0 113000.0 0.56 0.9633 0.9843 1853272 ChemDiv1_011513 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L08 compound treatment 745297.0 169000.0 0.76 668689.0 82400.0 0.41 0.8239 0.958 1781697 ChemDiv1_011514 COC(=O)C1C(C(=C(NC1=O)SCC(=O)OCc2ccccc2)C#N)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L09 compound treatment 751211.0 175000.0 0.78 715390.0 129000.0 0.64 1.0062 0.9949 1138674 ChemDiv1_011515 CCCC1=C(C(C(=C(N)O1)C#N)c2cc(OC)c(OC)c(OC)c2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L10 compound treatment 704328.0 128000.0 0.57 702923.0 117000.0 0.58 0.8141 1.0 1975668 ChemDiv1_011516 CSc1nnc(NC(=O)CSc2nn3c(SCC(=O)Nc4nnc(SC)s4)nnc3s2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L11 compound treatment 724343.0 148000.0 0.66 705936.0 120000.0 0.59 0.8881 0.9984 1975669 ChemDiv1_011517 FC(F)(F)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)cc(c1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L12 compound treatment 716766.0 141000.0 0.63 700534.0 114000.0 0.57 0.8451 0.9986 1578453 ChemDiv1_011518 COc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L13 compound treatment 722185.0 146000.0 0.65 687559.0 101000.0 0.5 0.8169 0.9915 1975670 ChemDiv1_011519 CCCCOC(=O)n1c(SCC(=O)OCC)nc2ccccc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L14 compound treatment 753352.0 177000.0 0.79 704087.0 118000.0 0.58 0.9734 0.9886 1925322 ChemDiv1_011520 FC(F)(F)COc1nc(nc(n1)N2CCN(Cc3ccccc3)CC2)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L15 compound treatment 795701.0 219000.0 0.98 809927.0 224000.0 1.11 1.4782 0.9982 1975671 ChemDiv1_011521 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCSc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L16 compound treatment 772330.0 196000.0 0.88 750866.0 165000.0 0.82 1.1973 0.9993 1975672 ChemDiv1_011522 Clc1cccc(NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L17 compound treatment 768620.0 192000.0 0.86 773625.0 187000.0 0.93 1.2653 0.9993 1975673 ChemDiv1_011523 COc1ccc(OCC(CN(C)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(C)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L18 compound treatment 776464.0 200000.0 0.9 740487.0 154000.0 0.76 1.1741 0.9968 1975674 ChemDiv1_011524 FC(F)(F)c1cc(nc2c(Br)c(nn12)C(=O)Nc3cccnc3)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L19 compound treatment 1844477.0 1270000.0 5.68 1811954.0 1230000.0 6.07 8.3078 0.9994 1360009 ChemDiv1_011525 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc4OCOc4cc3Br)c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L20 compound treatment 1340423.0 764000.0 3.42 1171639.0 585000.0 2.9 4.4694 0.9966 1250244 ChemDiv1_011526 CCOc1cc(ccc1OCc2ccccc2F)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L21 compound treatment 755086.0 179000.0 0.8 756838.0 171000.0 0.84 1.1637 0.9996 1591096 ChemDiv1_011527 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4ccc(OC(=O)C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L22 compound treatment 823385.0 247000.0 1.11 811052.0 225000.0 1.11 1.5698 1.0 1931161 ChemDiv1_011528 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4c(O)ccc5ccccc45)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L23 mock treatment 713549.0 137000.0 0.61 706624.0 120000.0 0.6 0.8563 0.9999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 L24 mock treatment 515134.0 -61100.0 -0.27 501427.0 -84800.0 -0.42 -0.4905 -0.9783 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M01 compound treatment 595140.0 18900.0 0.08 579859.0 -6410.0 -0.03 0.0375 0.414 1540637 ChemDiv1_011529 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3OC)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M02 compound treatment 641002.0 64800.0 0.29 619695.0 33400.0 0.17 0.3222 0.9647 1975675 ChemDiv1_011530 CC(C)Oc1ccccc1NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M03 compound treatment 869754.0 294000.0 1.31 812999.0 227000.0 1.12 1.7233 0.9969 1975676 ChemDiv1_011531 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)[C@@H](c23)c4ccccc4[N+](=O)[O-])N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M04 compound treatment 680076.0 104000.0 0.46 637095.0 50800.0 0.25 0.5068 0.9585 1975677 ChemDiv1_011532 Cc1cccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M05 compound treatment 673618.0 97400.0 0.44 665910.0 79600.0 0.39 0.5873 0.9988 1210220 ChemDiv1_011533 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OCc5ccc(Cl)cc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M06 compound treatment 725105.0 149000.0 0.67 743471.0 157000.0 0.78 1.0219 0.997 1509043 ChemDiv1_011534 CCOc1cc(ccc1OC)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M07 compound treatment 733869.0 158000.0 0.71 684661.0 98400.0 0.49 0.8437 0.9837 1975678 ChemDiv1_011535 Cc1ccc(cc1)C2=N/C(=C\c3ccccc3OS(=O)(=O)c4ccccc4)/C(=O)O2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M08 compound treatment 763359.0 187000.0 0.84 704313.0 118000.0 0.58 1.0059 0.9846 1975679 ChemDiv1_011536 COc1ccc(OC)c(/C=C\2/S/C(=N\c3ccc(C)cc3)/NC2=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M09 compound treatment 704935.0 129000.0 0.58 668327.0 82100.0 0.41 0.6949 0.9854 1616404 ChemDiv1_011537 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M10 compound treatment 696554.0 120000.0 0.54 669013.0 82700.0 0.41 0.6708 0.9909 1396344 ChemDiv1_011538 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc5ccccc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M11 compound treatment 699574.0 123000.0 0.55 709727.0 123000.0 0.61 0.8229 0.9987 1975680 ChemDiv1_011539 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3cccc(C)c3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M12 compound treatment 695188.0 119000.0 0.53 690952.0 105000.0 0.52 0.7433 0.9999 1975681 ChemDiv1_011540 CCCOc1ccc(/C=C\2/C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M13 compound treatment 730978.0 155000.0 0.69 708362.0 122000.0 0.6 0.9176 0.9977 1975682 ChemDiv1_011541 CCOC(=O)C1=C(CSc2nc(C)cc(C)c2C#N)OC(=C(C#N)C1c3ccc(OC)c(Br)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M14 compound treatment 737070.0 161000.0 0.72 720050.0 134000.0 0.66 0.9778 0.9991 1975683 ChemDiv1_011542 COc1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M15 compound treatment 776520.0 200000.0 0.9 746347.0 160000.0 0.79 1.1948 0.9981 1222027 ChemDiv1_011543 CCC1=NN(C(=O)c2ccc(C)cc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M16 compound treatment 702938.0 127000.0 0.57 697097.0 111000.0 0.55 0.7893 0.9999 1975684 ChemDiv1_011544 CC(=O)c1ccc(NC(=O)CSc2nn3c(SCC(=O)Nc4ccc(cc4)C(=O)C)nnc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M17 compound treatment 841145.0 265000.0 1.19 783748.0 197000.0 0.98 1.5303 0.9954 1975685 ChemDiv1_011545 COc1cc(cc(OC)c1OC)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)OCCOc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M18 compound treatment 764533.0 188000.0 0.84 749315.0 163000.0 0.81 1.1672 0.9998 1708889 ChemDiv1_011546 Cc1ccc(cc1)S(=O)CC(O)CSc2nc(C)c3CCCCc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M19 compound treatment 734562.0 158000.0 0.71 709179.0 123000.0 0.61 0.9318 0.9971 1462285 ChemDiv1_011547 CCOC(=O)c1c(CN2CCCCC2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M20 compound treatment 4141332.0 3570000.0 15.96 3752651.0 3170000.0 15.69 22.376 1.0 1572523 ChemDiv1_011548 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)c(O)c(OC)c3)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M21 compound treatment 1116628.0 540000.0 2.42 1060638.0 474000.0 2.35 3.3722 0.9999 1975686 ChemDiv1_011549 COC(=O)c1c(sc2CCCCc12)N3C(=C(C#N)C(C4=C3CCCC4=O)c5ccsc5)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M22 compound treatment 2705044.0 2130000.0 9.53 2666403.0 2080000.0 10.3 14.0248 0.9992 1483860 ChemDiv1_011550 CCOC(=O)c1c(CN2CCN(Cc3ccccc3)CC2)n(c4ccccc4)c5cc(Br)c(OC)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M23 mock treatment 700951.0 125000.0 0.56 694488.0 108000.0 0.54 0.7739 0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 M24 mock treatment 400413.0 -176000.0 -0.79 395953.0 -190000.0 -0.94 -1.2231 -0.996 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N01 compound treatment 603818.0 27600.0 0.12 587622.0 1350.0 0.01 0.0921 0.7443 1975687 ChemDiv1_011551 O=C(CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1)Nc3nc4ccccc4s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N02 compound treatment 662389.0 86200.0 0.39 595993.0 9720.0 0.05 0.3068 0.7893 1608225 ChemDiv1_011552 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OC)cc3C)c(=O)n2C1c4cc(OC)ccc4OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N03 compound treatment 695088.0 119000.0 0.53 640227.0 54000.0 0.27 0.5653 0.9493 1614470 ChemDiv1_011553 COc1ccc(N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccccc4)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N04 compound treatment 693974.0 118000.0 0.53 634835.0 48600.0 0.24 0.5429 0.9369 1559628 ChemDiv1_011554 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N05 compound treatment 721909.0 146000.0 0.65 667772.0 81500.0 0.4 0.7467 0.9734 1975688 ChemDiv1_011555 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N06 compound treatment 693554.0 117000.0 0.53 635844.0 49600.0 0.25 0.5451 0.94 1975689 ChemDiv1_011556 CCC(SCCSC(CC)C(=O)Nc1nnc(C)s1)C(=O)Nc2nnc(C)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N07 compound treatment 680507.0 104000.0 0.47 688344.0 102000.0 0.51 0.6877 0.9992 1975690 ChemDiv1_011557 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccs4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N08 compound treatment 724386.0 148000.0 0.66 695063.0 109000.0 0.54 0.8501 0.9947 1781699 ChemDiv1_011558 CCOC(=O)C1C(C(=C(NC1=O)SCc2ccccc2)C#N)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N09 compound treatment 724190.0 148000.0 0.66 676031.0 89800.0 0.44 0.7828 0.9812 1975691 ChemDiv1_011559 CCOc1ccc2nc(NC(=O)C3CC=CCC3C(=O)OCC(F)(F)C(F)F)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N10 compound treatment 715242.0 139000.0 0.62 668197.0 81900.0 0.41 0.7271 0.9785 1975692 ChemDiv1_011560 Cc1cccc(c1)C(=O)N2N=C(CC2(O)c3cccc(c3)[N+](=O)[O-])C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N11 compound treatment 735867.0 160000.0 0.71 719804.0 134000.0 0.66 0.9731 0.9993 1975693 ChemDiv1_011561 COC(=O)c1ccc(Nc2nc(C)c([N+](=O)[O-])c(Nc3ccc(cc3)C(=O)OC)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N12 compound treatment 699655.0 123000.0 0.55 654015.0 67700.0 0.34 0.628 0.9714 1975694 ChemDiv1_011562 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N13 compound treatment 743872.0 168000.0 0.75 730839.0 145000.0 0.72 1.0371 0.9997 1975695 ChemDiv1_011563 CCOc1ccc2nc(Sc3ccc(C=C4C(=O)NC(=O)NC4=O)o3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N14 compound treatment 701584.0 125000.0 0.56 671929.0 85700.0 0.42 0.6969 0.9905 1975696 ChemDiv1_011564 Nc1ccc(cc1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N15 compound treatment 784334.0 208000.0 0.93 720701.0 134000.0 0.67 1.1297 0.9865 1975697 ChemDiv1_011565 [O-][N+](=O)c1ccccc1S(=O)(=O)NCCSc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N16 compound treatment 724849.0 149000.0 0.67 694148.0 108000.0 0.53 0.8484 0.9941 1975698 ChemDiv1_011566 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)Nc3cccc4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N17 compound treatment 983287.0 407000.0 1.82 963067.0 377000.0 1.87 2.6084 0.9999 1255865 ChemDiv1_011567 CC1SC2(N(C1=O)c3cccc(Cl)c3)C(=O)N(CN4CCCCC4)c5ccccc52 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N18 compound treatment 881564.0 305000.0 1.37 804431.0 218000.0 1.08 1.7307 0.9932 1975699 ChemDiv1_011568 Clc1ccccc1NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N19 compound treatment 7101446.0 6530000.0 29.21 6464831.0 5880000.0 29.12 41.246 1.0 1148673 ChemDiv1_011569 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(OC)c(O)cc3Br)c(=O)n2C1c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N20 compound treatment 787028.0 211000.0 0.94 750095.0 164000.0 0.81 1.2412 0.9972 1310494 ChemDiv1_011570 COc1cc(cc2sc(=O)oc12)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N21 compound treatment 1507303.0 931000.0 4.17 1420529.0 834000.0 4.13 5.8695 1.0 1496720 ChemDiv1_011571 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccccc3O)c(=O)n2C1c4cc(OC)c(OC)cc4Br 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N22 compound treatment 744930.0 169000.0 0.76 712515.0 126000.0 0.63 0.9763 0.9956 1975700 ChemDiv1_011572 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NCCOc4ccccc4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N23 mock treatment 708711.0 132000.0 0.59 668206.0 81900.0 0.41 0.7064 0.9829 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 N24 mock treatment 416964.0 -159000.0 -0.71 423801.0 -162000.0 -0.8 -1.0732 -0.9982 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O01 compound treatment 591407.0 15200.0 0.07 567909.0 -18400.0 -0.09 -0.0162 -0.1428 1975701 ChemDiv1_011573 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccccc3C)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O02 compound treatment 619166.0 43000.0 0.19 582977.0 -3290.0 -0.02 0.1244 0.6448 1975702 ChemDiv1_011574 CCCOc1ccccc1C2NC(=O)NC(=C2C(=O)OCCOc3ccccc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O03 compound treatment 646107.0 69900.0 0.31 617044.0 30800.0 0.15 0.329 0.9454 1171178 ChemDiv1_011575 CC1=C(C(=O)OCC=C)C2(C(=O)Nc3ccc(C)cc32)C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O04 compound treatment 649371.0 73200.0 0.33 596659.0 10400.0 0.05 0.268 0.8083 1589790 ChemDiv1_011576 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O05 compound treatment 662777.0 86600.0 0.39 609343.0 23100.0 0.11 0.3548 0.8783 1975703 ChemDiv1_011577 [O-][N+](=O)c1cc(Cl)ccc1NC(=O)CSc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O06 compound treatment 655361.0 79100.0 0.35 601919.0 15600.0 0.08 0.3053 0.8419 1975704 ChemDiv1_011578 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)CN3CCCCC3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O07 compound treatment 672388.0 96200.0 0.43 624279.0 38000.0 0.19 0.4376 0.9312 1467397 ChemDiv1_011579 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccccc4F)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O08 compound treatment 685766.0 110000.0 0.49 640410.0 54100.0 0.27 0.5364 0.9597 1614923 ChemDiv1_011580 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc4OCOc4c3)c(=O)n2C1c5cc(OC)ccc5OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O09 compound treatment 677041.0 101000.0 0.45 640219.0 53900.0 0.27 0.5081 0.9687 1220001 ChemDiv1_011581 CC1SC2(N(C1=O)c3cccc(F)c3)C(=O)Nc4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O10 compound treatment 678803.0 103000.0 0.46 632037.0 45800.0 0.23 0.485 0.9471 1261609 ChemDiv1_011582 CC(C)COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O11 compound treatment 737741.0 162000.0 0.72 720610.0 134000.0 0.67 0.9819 0.9991 1975705 ChemDiv1_011583 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O12 compound treatment 645492.0 69300.0 0.31 639142.0 52900.0 0.26 0.4045 0.9965 1975706 ChemDiv1_011584 CCSc1nc2ccccc2n1CC(=O)Nc3ccc(cc3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O13 compound treatment 700081.0 124000.0 0.55 676779.0 90500.0 0.45 0.7091 0.9944 1555543 ChemDiv1_011585 CCCC1=C(C(=O)OCC)C2(C(=O)Nc3ccc(Cl)cc32)C(=C(N)O1)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O14 compound treatment 689860.0 114000.0 0.51 670566.0 84300.0 0.42 0.655 0.9952 1975707 ChemDiv1_011586 COc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(OC)c(OC)c3)/S2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O15 compound treatment 724681.0 148000.0 0.66 706277.0 120000.0 0.59 0.8903 0.9985 1927567 ChemDiv1_011587 CCC1=NN(C(=O)c2ccc(Cl)cc2)C(O)(C1)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O16 compound treatment 815155.0 239000.0 1.07 772027.0 186000.0 0.92 1.407 0.9972 1410430 ChemDiv1_011588 COc1cc(ccc1OCC#N)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O17 compound treatment 855700.0 279000.0 1.25 852095.0 266000.0 1.32 1.8158 0.9997 1535801 ChemDiv1_011589 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OC)c(OC)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O18 compound treatment 666319.0 90100.0 0.4 628885.0 42600.0 0.21 0.4345 0.9544 1975708 ChemDiv1_011590 COc1cc(/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3C)cc([N+](=O)[O-])c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O19 compound treatment 648237.0 72000.0 0.32 638385.0 52100.0 0.26 0.4105 0.9939 1975709 ChemDiv1_011591 O=C1c2ccccc2C(=O)c3cc(NS(=O)(=O)c4ccc5C(=O)c6ccccc6C(=O)c5c4)ccc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O20 compound treatment 670813.0 94600.0 0.42 664044.0 77800.0 0.39 0.5719 0.9989 1729713 ChemDiv1_011592 CCOc1cc(Br)c(C=c2sc3nc4ccccc4n3c2=O)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O21 compound treatment 738384.0 162000.0 0.73 722504.0 136000.0 0.67 0.9905 0.9993 1425769 ChemDiv1_011593 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccnc3)N)c4sc5CCCCc5c4C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O22 compound treatment 669198.0 93000.0 0.42 643747.0 57500.0 0.28 0.4957 0.9829 1975710 ChemDiv1_011594 Cc1cc(C)c(C#N)c(SCc2n[nH]c3OC(=C(C#N)C(c23)c4ccc(F)cc4)N)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O23 mock treatment 662099.0 85900.0 0.38 631813.0 45500.0 0.23 0.4314 0.9677 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 O24 mock treatment 407249.0 -169000.0 -0.76 419519.0 -167000.0 -0.83 -1.1189 -0.999 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P01 compound treatment 590661.0 14400.0 0.06 575765.0 -10500.0 -0.05 0.0089 0.1077 1975711 ChemDiv1_011595 CCCCOc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P02 compound treatment 589533.0 13300.0 0.06 580205.0 -6060.0 -0.03 0.0209 0.3133 1975712 ChemDiv1_011596 COc1ccc(cc1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P03 compound treatment 602599.0 26400.0 0.12 595150.0 8880.0 0.04 0.1146 0.9094 1975713 ChemDiv1_011597 CC(C)COC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc3cc(C)cc(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P04 compound treatment 581849.0 5640.0 0.03 596899.0 10600.0 0.05 0.0551 0.9433 1781700 ChemDiv1_011598 CCOC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccccc3[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P05 compound treatment 611130.0 34900.0 0.16 610458.0 24200.0 0.12 0.1953 0.9914 1975714 ChemDiv1_011599 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4Cl)cc3s2)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P06 compound treatment 623778.0 47600.0 0.21 601956.0 15700.0 0.08 0.2055 0.9067 1365022 ChemDiv1_011600 CCOc1ccc(Nc2nc(nc(n2)N3CCOCC3)N4CCOCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P07 compound treatment 628840.0 52600.0 0.24 621905.0 35600.0 0.18 0.2914 0.9899 1197385 ChemDiv1_011601 COc1ccc(cc1)C2C(=C(N)OC(=C2C(=O)OCC=C)C)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P08 compound treatment 637491.0 61300.0 0.27 625002.0 38700.0 0.19 0.3296 0.9847 1340607 ChemDiv1_011602 Cc1nc(SCC(=O)c2cc3ccccc3oc2=O)c(C#N)c(C)c1C(=O)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P09 compound treatment 654779.0 78600.0 0.35 670724.0 84500.0 0.42 0.5445 0.9963 1975715 ChemDiv1_011603 COc1ccc(Nc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P10 compound treatment 1221139.0 645000.0 2.89 1143763.0 557000.0 2.76 3.9942 0.9998 1975716 ChemDiv1_011604 CCSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P11 compound treatment 1316984.0 741000.0 3.32 1283572.0 697000.0 3.45 4.7873 0.9998 1975717 ChemDiv1_011605 CN(C)c1ccc(/C=C\2/S/C(=N/c3ccc4ccccc4c3)/NC2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P12 compound treatment 662426.0 86200.0 0.39 665496.0 79200.0 0.39 0.5504 1.0 1975718 ChemDiv1_011606 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)Nc4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P13 compound treatment 694603.0 118000.0 0.53 690333.0 104000.0 0.52 0.7393 0.9999 1734607 ChemDiv1_011607 CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Cl)ccc3O)c(=O)n2C1c4ccc5OCOc5c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P14 compound treatment 638710.0 62500.0 0.28 623928.0 37700.0 0.19 0.3297 0.9806 1975719 ChemDiv1_011608 C1C(N(N=C1c2cccs2)c3nc(cs3)c4ccc5ccccc5c4)c6ccoc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P15 compound treatment 622422.0 46200.0 0.21 639188.0 52900.0 0.26 0.3316 0.9931 1645829 ChemDiv1_011609 COc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P16 compound treatment 668642.0 92400.0 0.41 660078.0 73800.0 0.37 0.5511 0.9981 1695372 ChemDiv1_011610 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NC3CCCCCC3)OCc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P17 compound treatment 647793.0 71600.0 0.32 644014.0 57700.0 0.29 0.4288 0.9984 1557456 ChemDiv1_011611 COc1ccccc1Nc2nc3nonc3nc2N4CCC(C)CC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P18 compound treatment 657649.0 81400.0 0.36 674461.0 88200.0 0.44 0.5667 0.996 1975720 ChemDiv1_011612 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccccc3Cl)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P19 compound treatment 729596.0 153000.0 0.69 698445.0 112000.0 0.56 0.8784 0.9945 1975721 ChemDiv1_011613 O=C(Oc1ccc(NC2=NS(=O)(=O)c3ccccc23)cc1CN4CCCCC4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P20 compound treatment 627408.0 51200.0 0.23 653227.0 67000.0 0.33 0.3966 0.9837 1177064 ChemDiv1_011614 COc1cc(cc(OC)c1OCc2ccc(Cl)c(Cl)c2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P21 compound treatment 634163.0 58000.0 0.26 652110.0 65800.0 0.33 0.4141 0.9936 1975722 ChemDiv1_011615 CC1SC2(N(C1=O)c3ccc(Cl)c(Cl)c3)C(=O)Nc4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P22 compound treatment 674476.0 98300.0 0.44 686644.0 100000.0 0.5 0.6626 0.9981 1975723 ChemDiv1_011616 CCOC(=O)c1cnn(c1NC(=O)CSc2nc3ccccc3[nH]2)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P23 mock treatment 616169.0 40000.0 0.18 606883.0 20600.0 0.1 0.1987 0.9647 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.619 P24 mock treatment 150783.0 -425000.0 -1.9 456725.0 -130000.0 -0.64 -1.8004 -0.8959 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A01 compound treatment 564563.0 5730.0 0.03 587121.0 34500.0 0.17 0.1389 0.8043 1496956 ChemDiv1_011617 Clc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cc6cc(Br)ccc6o5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A02 compound treatment 561723.0 2890.0 0.01 575381.0 22700.0 0.11 0.0888 0.7832 1945441 ChemDiv1_011618 CCCC1=NN(C(=O)Cc2ccc(OC)c(OC)c2)C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A03 compound treatment 560652.0 1820.0 0.01 594223.0 41600.0 0.21 0.1514 0.7345 1975724 ChemDiv1_011619 COc1ccc(cc1)C(=O)OCCN(C2=NS(=O)(=O)c3ccccc23)c4cccc(C)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A04 compound treatment 562437.0 3600.0 0.02 585773.0 33100.0 0.16 0.1275 0.7729 1975725 ChemDiv1_011620 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccc5OCOc5c4)c6cccs6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A05 compound treatment 589290.0 30500.0 0.14 606932.0 54300.0 0.27 0.2866 0.9504 1932920 ChemDiv1_011621 COc1cc(ccc1OCc2cc3OCOc3cc2Cl)C4C5=C(CC(C)(C)CC5=O)OC6=C4C(=O)CC(C)(C)C6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A06 compound treatment 599756.0 40900.0 0.18 621824.0 69200.0 0.34 0.3719 0.9569 1975726 ChemDiv1_011622 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(F)c(F)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A07 compound treatment 622747.0 63900.0 0.29 652176.0 99500.0 0.49 0.551 0.9665 1975727 ChemDiv1_011623 CC(=O)/N=C\1/NC(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3Cl)/S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A08 compound treatment 615878.0 57000.0 0.26 638638.0 86000.0 0.43 0.4818 0.97 1975728 ChemDiv1_011624 CCCCCOc1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A09 compound treatment 611704.0 52900.0 0.24 642915.0 90300.0 0.45 0.4836 0.9557 1975729 ChemDiv1_011625 CC(C)OC(=O)C1=C(C)OC(=C(C#N)C1c2cccnc2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A10 compound treatment 595260.0 36400.0 0.16 652776.0 100000.0 0.5 0.4661 0.8926 1975730 ChemDiv1_011626 COc1ccc(OCC(CN(C)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(OC)cc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A11 compound treatment 611968.0 53100.0 0.24 648076.0 95400.0 0.47 0.5025 0.9495 1574144 ChemDiv1_011627 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(Cc3ccccc3)c4cc(Br)c(O)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A12 compound treatment 594850.0 36000.0 0.16 636330.0 83700.0 0.41 0.4072 0.9153 1610779 ChemDiv1_011628 Clc1ccc(cc1Cl)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A13 compound treatment 611778.0 52900.0 0.24 626260.0 73600.0 0.36 0.4255 0.9782 1169058 ChemDiv1_011629 Cc1nnc(SCC(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A14 compound treatment 601300.0 42500.0 0.19 654003.0 101000.0 0.5 0.4895 0.9117 1975731 ChemDiv1_011630 COc1cc(cc(OC)c1OC)C(=O)N2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A15 compound treatment 610291.0 51500.0 0.23 656856.0 104000.0 0.52 0.5279 0.9339 1975732 ChemDiv1_011631 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3ccccc3[N+](=O)[O-])c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A16 compound treatment 613174.0 54300.0 0.24 648507.0 95900.0 0.47 0.5078 0.9517 1250464 ChemDiv1_011632 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)c4cccc(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A17 compound treatment 627160.0 68300.0 0.31 648311.0 95700.0 0.47 0.5514 0.9776 1717010 ChemDiv1_011633 OC(CSc1nc(cc(c1C#N)c2ccccc2)c3ccccc3)CN4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A18 compound treatment 614161.0 55300.0 0.25 633347.0 80700.0 0.4 0.4578 0.9735 1975733 ChemDiv1_011634 Cc1ccnc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C4CCCCC4C3=O)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A19 compound treatment 599384.0 40600.0 0.18 653263.0 101000.0 0.5 0.4808 0.9064 1429163 ChemDiv1_011635 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A20 compound treatment 590426.0 31600.0 0.14 618040.0 65400.0 0.32 0.3291 0.9309 1975734 ChemDiv1_011636 CC1CC(N(C(=O)C)c2ccccc2)c3ccccc3N1C(=O)/C=C/c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A21 compound treatment 597339.0 38500.0 0.17 619226.0 66600.0 0.33 0.3551 0.9542 1169790 ChemDiv1_011637 Fc1ccc(cc1F)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A22 compound treatment 580187.0 21400.0 0.1 607766.0 55100.0 0.27 0.2607 0.901 1265866 ChemDiv1_011638 CC1SC2(N(C1=O)c3ccc(C)c(Cl)c3)C(=O)Nc4ccccc42 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A23 mock treatment 572449.0 13600.0 0.06 584592.0 32000.0 0.16 0.155 0.914 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 A24 mock treatment 542375.0 -16500.0 -0.07 504463.0 -48200.0 -0.24 -0.2209 -0.8842 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B01 compound treatment 575559.0 16700.0 0.07 592639.0 40000.0 0.2 0.193 0.9114 1125898 ChemDiv1_011639 CC1(C)CC(=O)c2sc(NC(=O)CSc3nc4ccccc4[nH]3)nc2C1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B02 compound treatment 569045.0 10200.0 0.05 601649.0 49000.0 0.24 0.204 0.8257 1975735 ChemDiv1_011640 Fc1ccccc1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B03 compound treatment 598157.0 39300.0 0.18 625822.0 73200.0 0.36 0.3808 0.945 1975736 ChemDiv1_011641 Nc1nc(SCC(=O)c2ccc(O)c(O)c2)c(C#N)c(c1C#N)c3cccc(Cl)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B04 compound treatment 589481.0 30600.0 0.14 626122.0 73500.0 0.36 0.3544 0.9111 1300987 ChemDiv1_011642 Brc1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCN(Cc5ccccc5)CC4)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B05 compound treatment 636372.0 77500.0 0.35 658736.0 106000.0 0.53 0.6171 0.9797 1975737 ChemDiv1_011643 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(Br)cc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B06 compound treatment 619580.0 60700.0 0.27 642800.0 90200.0 0.45 0.5081 0.9717 1415944 ChemDiv1_011644 CCOC(=O)c1c(CN2CCC(CC2)(C(=O)OCC)c3ccccc3)n(Cc4ccccc4)c5cc(Br)c(O)cc15 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B07 compound treatment 630883.0 72100.0 0.32 667920.0 115000.0 0.57 0.6319 0.9634 1731250 ChemDiv1_011645 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B08 compound treatment 632099.0 73300.0 0.33 673336.0 121000.0 0.6 0.6547 0.96 1975738 ChemDiv1_011646 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NC(C)C)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B09 compound treatment 667028.0 108000.0 0.48 694023.0 141000.0 0.7 0.8377 0.9838 1975739 ChemDiv1_011647 Cc1ccc(NC(=O)c2c(C)nc(S)c(C#N)c2c3cccs3)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B10 compound treatment 640495.0 81700.0 0.37 659141.0 106000.0 0.53 0.6315 0.9839 1975740 ChemDiv1_011648 Cc1sc2nc(oc(=O)c2c1C)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B11 compound treatment 658223.0 99400.0 0.44 694453.0 142000.0 0.7 0.8113 0.9757 1617551 ChemDiv1_011649 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(SC)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B12 compound treatment 628971.0 70100.0 0.31 651076.0 98400.0 0.49 0.5668 0.9773 1975741 ChemDiv1_011650 NNc1nc(Nc2ccccc2[N+](=O)[O-])nc(OC(C(F)(F)F)C(F)(F)F)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B13 compound treatment 648922.0 90100.0 0.4 673458.0 121000.0 0.6 0.7084 0.9815 1415881 ChemDiv1_011651 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccccc2Cl)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B14 compound treatment 647902.0 89100.0 0.4 678574.0 126000.0 0.62 0.7231 0.9766 1975742 ChemDiv1_011652 CCC(=O)Nc1ccc2nc(SCc3cc(ccc3OC)[N+](=O)[O-])sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B15 compound treatment 679756.0 121000.0 0.54 698950.0 146000.0 0.72 0.8953 0.9897 1640880 ChemDiv1_011653 CCOC(=O)c1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B16 compound treatment 646929.0 88100.0 0.39 667352.0 115000.0 0.57 0.6807 0.9841 1781290 ChemDiv1_011654 CC1CC(N(C(=O)c2ccc(Cl)cc2Cl)c3ccccc3)c4ccccc4N1C(=O)c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B17 compound treatment 676751.0 118000.0 0.53 696987.0 144000.0 0.72 0.8789 0.9888 1204897 ChemDiv1_011655 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5cccc(F)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B18 compound treatment 632542.0 73700.0 0.33 655949.0 103000.0 0.51 0.5952 0.9775 1204933 ChemDiv1_011656 CC1(COC2(OC1)C(=O)N(CN3CCOCC3)c4ccccc42)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B19 compound treatment 633643.0 74800.0 0.33 662003.0 109000.0 0.54 0.6199 0.9733 1615271 ChemDiv1_011657 COc1ccccc1N2C(=O)c3ccccc3NC24C(=O)N(Cc5c(Cl)cccc5Cl)c6ccccc64 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B20 compound treatment 627797.0 69000.0 0.31 632920.0 80300.0 0.4 0.4995 0.9922 1975743 ChemDiv1_011658 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC)cc3CSc4ccccn4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B21 compound treatment 632116.0 73300.0 0.33 649481.0 96800.0 0.48 0.5712 0.9828 1975744 ChemDiv1_011659 Clc1cccc(Cl)c1CN2C(=O)C3(Nc4sc5CCCCc5c4C(=O)N3CCc6ccccc6)c7ccccc27 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B22 compound treatment 592559.0 33700.0 0.15 620353.0 67700.0 0.34 0.3439 0.935 1732080 ChemDiv1_011660 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(c34)c5ccccc5)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B23 mock treatment 618428.0 59600.0 0.27 632945.0 80300.0 0.4 0.4699 0.9811 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 B24 mock treatment 484886.0 -73900.0 -0.33 493188.0 -59500.0 -0.29 -0.4423 -0.9983 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C01 compound treatment 544996.0 -13800.0 -0.06 584623.0 32000.0 0.16 0.0682 0.4011 1975745 ChemDiv1_011661 CCC(=O)Oc1ccc(/C=C\2/C(=NN(C2=O)c3cccc(Br)c3)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C02 compound treatment 582963.0 24100.0 0.11 600727.0 48100.0 0.24 0.2448 0.936 1975746 ChemDiv1_011662 COc1ccc(CC(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C03 compound treatment 628778.0 69900.0 0.31 648930.0 96300.0 0.48 0.5587 0.9792 1531497 ChemDiv1_011663 CC(C)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nnnn4C)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C04 compound treatment 595764.0 36900.0 0.17 632828.0 80200.0 0.4 0.3978 0.9245 1455557 ChemDiv1_011664 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C05 compound treatment 645345.0 86500.0 0.39 656361.0 104000.0 0.51 0.6372 0.9903 1975747 ChemDiv1_011665 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cn(Cc5ccc(Cl)c(Cl)c5)nc4c6ccccc6)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C06 compound treatment 635500.0 76700.0 0.34 630760.0 78100.0 0.39 0.5163 0.9982 1147089 ChemDiv1_011666 Brc1ccc2oc(cc2c1)C(=O)N3CCc4c(C3)[nH]c5ccccc45 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C07 compound treatment 658156.0 99300.0 0.44 674475.0 122000.0 0.6 0.7412 0.9887 1220515 ChemDiv1_011667 COc1cc(cc(OC)c1OC(=O)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C08 compound treatment 658605.0 99800.0 0.45 681238.0 129000.0 0.64 0.7663 0.9849 1975748 ChemDiv1_011668 Cc1cc2nc3sc(=Cc4cn(Cc5ccccc5F)c6ccccc46)c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C09 compound treatment 999171.0 440000.0 1.97 1019991.0 467000.0 2.32 3.0309 0.9968 1975749 ChemDiv1_011669 Clc1ccc(Cn2cc(/C=C/3\SC(=N)NC3=O)c4ccccc24)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C10 compound treatment 898902.0 340000.0 1.52 748896.0 196000.0 0.97 1.7639 0.9765 1975750 ChemDiv1_011670 COc1ccc(/C=C/2\S\C(=N\c3cccc4ccccc34)\NC2=O)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C11 compound treatment 706097.0 147000.0 0.66 753840.0 201000.0 1.0 1.1709 0.9799 1646097 ChemDiv1_011671 O=C(CSc1nc2ccccc2s1)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C12 compound treatment 645069.0 86200.0 0.39 665703.0 113000.0 0.56 0.669 0.9835 1146046 ChemDiv1_011672 Clc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C13 compound treatment 674268.0 115000.0 0.52 685142.0 133000.0 0.66 0.8295 0.993 1688121 ChemDiv1_011673 COc1ccccc1NC(=O)CSc2nc3ccc(NC(=O)CSc4nncn4C)cc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C14 compound treatment 664731.0 106000.0 0.47 672355.0 120000.0 0.59 0.7545 0.9938 1149509 ChemDiv1_011674 CCOC(=O)c1c(CN2CCN(CCO)CC2)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C15 compound treatment 713385.0 155000.0 0.69 760669.0 208000.0 1.03 1.2179 0.9812 1975751 ChemDiv1_011675 COc1ccc(/C=C/2\SC(=N)N(C2=O)c3ccc(C)c(C)c3)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C16 compound treatment 645435.0 86600.0 0.39 659239.0 107000.0 0.53 0.6475 0.9885 1263179 ChemDiv1_011676 COc1ccc2oc(C)c(C(=O)c3oc4ccccc4c3N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C17 compound treatment 685366.0 127000.0 0.57 704252.0 152000.0 0.75 0.9316 0.9903 1238089 ChemDiv1_011677 Cc1nc2sc(C#N)c(N)c2c(C)c1CC(=O)c3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C18 compound treatment 634147.0 75300.0 0.34 647172.0 94500.0 0.47 0.5695 0.987 1559227 ChemDiv1_011678 O=C(CSc1ccccn1)N2CCN(CC2)C(=O)CSc3ccccn3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C19 compound treatment 707142.0 148000.0 0.66 697984.0 145000.0 0.72 0.9786 0.9992 1496776 ChemDiv1_011679 Cc1ccc2c(N)c(sc2n1)C(=O)c3ccc(cc3)C(=O)c4sc5nc(C)ccc5c4N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C20 compound treatment 564599.0 5770.0 0.03 581835.0 29200.0 0.14 0.1205 0.8204 1975752 ChemDiv1_011680 CCc1ccc2NC(=O)C3(NN=C(S3)c4ccc(C)cc4)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C21 compound treatment 654499.0 95700.0 0.43 666789.0 114000.0 0.57 0.7027 0.9906 1227832 ChemDiv1_011681 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C22 compound treatment 611979.0 53100.0 0.24 630962.0 78300.0 0.39 0.4426 0.9724 1342902 ChemDiv1_011682 CCOc1ccc(NC(=O)Cn2c(SCC)nc3ccccc23)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C23 mock treatment 633165.0 74300.0 0.33 648708.0 96100.0 0.48 0.5718 0.9847 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 C24 mock treatment 512412.0 -46400.0 -0.21 508933.0 -43700.0 -0.22 -0.3 -0.9998 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D01 compound treatment 560512.0 1680.0 0.01 585798.0 33200.0 0.16 0.1215 0.7387 1220149 ChemDiv1_011683 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D02 compound treatment 575968.0 17100.0 0.08 584776.0 32100.0 0.16 0.1668 0.944 1609886 ChemDiv1_011684 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D03 compound treatment 619751.0 60900.0 0.27 630109.0 77500.0 0.38 0.4642 0.986 1405796 ChemDiv1_011685 CC(C)Cc1c(C#N)c(SCC(=O)c2ccc(O)c(O)c2)nc(C)c1C(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D04 compound treatment 601544.0 42700.0 0.19 611130.0 58500.0 0.29 0.3401 0.9796 1353902 ChemDiv1_011686 CC(=O)Nc1ccc2nc(SCC(=O)N3CCc4ccccc34)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D05 compound treatment 649577.0 90700.0 0.41 656405.0 104000.0 0.51 0.6507 0.9932 1975753 ChemDiv1_011687 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3cccs3)N)c4ccc(Br)cc4F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D06 compound treatment 630669.0 71800.0 0.32 635204.0 82600.0 0.41 0.5166 0.9929 1166738 ChemDiv1_011688 CCOC(=O)c1c(CN2CCCCC2)n(c3ccccc3)c4cc(Br)c(O)c(CN5CCOCC5)c14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D07 compound treatment 662485.0 104000.0 0.46 660933.0 108000.0 0.54 0.7074 0.9974 1509110 ChemDiv1_011689 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3Cc4ccccc4)cc2s1)Nc5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D08 compound treatment 627343.0 68500.0 0.31 666793.0 114000.0 0.57 0.6167 0.9587 1943170 ChemDiv1_011690 COc1ccc(cc1OC)c2cc(n3nc(C(=O)NCc4ccco4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D09 compound treatment 687480.0 129000.0 0.58 694143.0 142000.0 0.7 0.9029 0.9952 1975754 ChemDiv1_011691 CCCC1=C(C(C(=C(N)O1)C#N)c2ccc(OC)c(CSc3ccccn3)c2)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D10 compound treatment 673765.0 115000.0 0.51 663373.0 111000.0 0.55 0.7517 0.9995 1975755 ChemDiv1_011692 Cc1sc2nc(oc(=O)c2c1C)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D11 compound treatment 676135.0 117000.0 0.53 670995.0 118000.0 0.59 0.7859 0.9985 1975756 ChemDiv1_011693 Cc1ccsc1C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(cc4)S(=O)(=O)N)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D12 compound treatment 645790.0 87000.0 0.39 636200.0 83600.0 0.41 0.5679 0.9995 1975757 ChemDiv1_011694 COc1cc([N+](=O)[O-])c(Cl)cc1N/C=C\2/C(=NN(C2=O)c3cccc(Cl)c3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D13 compound treatment 744659.0 186000.0 0.83 752300.0 200000.0 0.99 1.2876 0.9963 1975758 ChemDiv1_011695 CC(C)OC(=O)CC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D14 compound treatment 662376.0 104000.0 0.46 665309.0 113000.0 0.56 0.7224 0.9957 1975759 ChemDiv1_011696 CCCCCOc1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCC(Cc5ccccc5)CC4)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D15 compound treatment 683251.0 124000.0 0.56 710474.0 158000.0 0.78 0.9467 0.9862 1975760 ChemDiv1_011697 Fc1ccccc1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5cccc(c5)C(F)(F)F)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D16 compound treatment 635559.0 76700.0 0.34 675292.0 123000.0 0.61 0.6725 0.9635 1391729 ChemDiv1_011698 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCN(CC4)c5ccc(F)cc5)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D17 compound treatment 664364.0 106000.0 0.47 684355.0 132000.0 0.65 0.7954 0.9874 1942832 ChemDiv1_011699 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)/C=C/c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D18 compound treatment 646976.0 88100.0 0.39 651454.0 98800.0 0.49 0.6251 0.9943 1438364 ChemDiv1_011700 Cc1cc2nc3sc(=Cc4cccc(OCc5c(F)cccc5Cl)c4)c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D19 compound treatment 663715.0 105000.0 0.47 651556.0 98900.0 0.49 0.6785 0.9998 1975761 ChemDiv1_011701 Cc1n[nH]c2OC(=C(C#N)C(c12)c3ccccc3OCc4cccc(Br)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D20 compound treatment 639820.0 81000.0 0.36 669361.0 117000.0 0.58 0.6652 0.9747 1975762 ChemDiv1_011702 CCCc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccccc43)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D21 compound treatment 655909.0 97100.0 0.43 673873.0 121000.0 0.6 0.7319 0.9874 1288456 ChemDiv1_011703 CCOC(=O)C1=C(N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc5OCOc5c4)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D22 compound treatment 614959.0 56100.0 0.25 629903.0 77300.0 0.38 0.4483 0.9792 1650569 ChemDiv1_011704 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccc(OC(=O)N5CCOCC5)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D23 mock treatment 644918.0 86100.0 0.39 631371.0 78700.0 0.39 0.5483 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 D24 mock treatment 491325.0 -67500.0 -0.3 482719.0 -69900.0 -0.35 -0.4586 -0.9977 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E01 compound treatment 577209.0 18400.0 0.08 595367.0 42700.0 0.21 0.2078 0.9152 1975763 ChemDiv1_011705 CCC(=O)Oc1ccc(/C=C\2/C(=NN(C2=O)c3cccc(c3)C(F)(F)F)C)cc1OC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E02 compound treatment 591647.0 32800.0 0.15 615246.0 62600.0 0.31 0.3232 0.9417 1975764 ChemDiv1_011706 OC1(CC(=NN1C(=O)c2cccc(Br)c2)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E03 compound treatment 720438.0 162000.0 0.72 744797.0 192000.0 0.95 1.1846 0.9908 1478562 ChemDiv1_011707 COc1cc(C=c2sc3nc4c(C)c(C)ccc4n3c2=O)cc(OC)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E04 compound treatment 614893.0 56100.0 0.25 659469.0 107000.0 0.53 0.5516 0.9419 1253426 ChemDiv1_011708 O=C(N1CCc2c([nH]c3ccccc23)C1c4ccccc4)c5cccs5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E05 compound treatment 631114.0 72300.0 0.32 660318.0 108000.0 0.53 0.606 0.9713 1975765 ChemDiv1_011709 O=C(CSc1nc2ccc(NC(=O)/C=C/c3ccccc3)cc2s1)NCC4CCCO4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E06 compound treatment 640465.0 81600.0 0.37 665938.0 113000.0 0.56 0.6553 0.9784 1117911 ChemDiv1_011710 Brc1ccc2oc(=O)c(cc2c1)C(=O)Nc3sc4CCCCc4c3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E07 compound treatment 1026175.0 467000.0 2.09 1016456.0 464000.0 2.3 3.1039 0.9989 1975766 ChemDiv1_011711 CCOc1cc(/C=C/2\S\C(=N\C(=O)C)\NC2=O)cc(Cl)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E08 compound treatment 641176.0 82300.0 0.37 678856.0 126000.0 0.63 0.7028 0.9682 1975767 ChemDiv1_011712 [O-][N+](=O)c1ccc(cc1)C2C(=C3NC(=O)c4c5CCCCc5sc4N3C6=C2C(=O)CCC6)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E09 compound treatment 674424.0 116000.0 0.52 696513.0 144000.0 0.71 0.8698 0.9876 1151059 ChemDiv1_011713 Cc1nc(cs1)c2cccc(NC(=O)c3cc4cc(Br)ccc4oc3=O)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E10 compound treatment 707220.0 148000.0 0.66 706050.0 153000.0 0.76 1.0071 0.9977 1491087 ChemDiv1_011714 CCSc1nc(N)c2c3CCN(Cc4ccccc4)Cc3sc2n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E11 compound treatment 692972.0 134000.0 0.6 713416.0 161000.0 0.8 0.9878 0.9903 1700724 ChemDiv1_011715 O=C(CSCC(=O)Nc1ccc2nc(SCC(=O)N3CCOCC3)sc2c1)Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E12 compound treatment 663437.0 105000.0 0.47 695258.0 143000.0 0.71 0.8307 0.98 1736969 ChemDiv1_011716 COc1ccccc1N2CCN(Cc3cc(Br)c(O)c4ncccc34)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E13 compound treatment 677150.0 118000.0 0.53 683419.0 131000.0 0.65 0.8326 0.995 1257341 ChemDiv1_011717 Cc1cc2nc3sc(=Cc4cc(Cl)ccc4OCc5c(F)cccc5Cl)c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E14 compound treatment 674028.0 115000.0 0.52 697914.0 145000.0 0.72 0.8735 0.9866 1509756 ChemDiv1_011718 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4cc(Br)c(OC(=O)C)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E15 compound treatment 681190.0 122000.0 0.55 728543.0 176000.0 0.87 1.0035 0.975 1593480 ChemDiv1_011719 CCOc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1OCc5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E16 compound treatment 680109.0 121000.0 0.54 709680.0 157000.0 0.78 0.934 0.9845 1365393 ChemDiv1_011720 COC(=O)COc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E17 compound treatment 666928.0 108000.0 0.48 729988.0 177000.0 0.88 0.9634 0.9605 1356645 ChemDiv1_011721 CCOC(=O)c1c(CSc2ccccc2)n(C)c3ccc(O)c(CN4CCOCC4)c13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E18 compound treatment 642064.0 83200.0 0.37 691070.0 138000.0 0.69 0.7483 0.9589 1360647 ChemDiv1_011722 COC(=O)CC(=O)Nc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E19 compound treatment 669923.0 111000.0 0.5 671350.0 119000.0 0.59 0.7675 0.9965 1226850 ChemDiv1_011723 Nc1c(sc2nc(N)c(C#N)c(c3ccccc3)c12)C(=O)c4ccc(Br)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E20 compound treatment 657837.0 99000.0 0.44 687422.0 135000.0 0.67 0.7855 0.9802 1488239 ChemDiv1_011724 CCC(=O)Nc1ccc2nc(SCC(=O)NCC3CCCO3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E21 compound treatment 650128.0 91300.0 0.41 686834.0 134000.0 0.66 0.759 0.9727 1975768 ChemDiv1_011725 O=C(Oc1cc2oc3ccccc3[nH]c2c4c(=O)c5ccccc5c(=O)c14)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E22 compound treatment 634234.0 75400.0 0.34 655900.0 103000.0 0.51 0.6004 0.9796 1975769 ChemDiv1_011726 [O-][N+](=O)c1ccc(cc1)N2CCN(CN3C(=O)C4(SCC(=O)N4c5cccc(Cl)c5)c6ccccc36)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E23 mock treatment 643631.0 84800.0 0.38 657232.0 105000.0 0.52 0.6348 0.9883 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 E24 mock treatment 557877.0 -955.0 0.0 511852.0 -40800.0 -0.2 -0.1459 -0.7219 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F01 compound treatment 558724.0 -108.0 0.0 584199.0 31600.0 0.16 0.1102 0.7049 1132732 ChemDiv1_011727 COc1ccc2oc(C(=O)c3ccc(Cl)cc3)c(N)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F02 compound treatment 596866.0 38000.0 0.17 612243.0 59600.0 0.3 0.3292 0.9658 1975770 ChemDiv1_011728 Cc1ccc2c(nc3sc(=Cc4cn(Cc5ccccc5)c6ccccc46)c(=O)n32)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F03 compound treatment 620600.0 61800.0 0.28 612515.0 59900.0 0.3 0.4052 0.9994 1975771 ChemDiv1_011729 COC(=O)C1C(C(=C(NC1=O)SCC(=O)Nc2ccc(Br)cc2)C#N)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F04 compound treatment 621752.0 62900.0 0.28 640253.0 87600.0 0.43 0.506 0.9781 1449252 ChemDiv1_011730 CCOC(=O)C1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)c(Cl)c4)c5ccccc25)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F05 compound treatment 641547.0 82700.0 0.37 656999.0 104000.0 0.52 0.6274 0.9866 1708230 ChemDiv1_011731 CCN(CC)C(=O)CSc1nc2ccccc2n1C(=O)NC3CCCCC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F06 compound treatment 617403.0 58600.0 0.26 642911.0 90300.0 0.45 0.5016 0.9676 1613231 ChemDiv1_011732 COC(=O)c1sc2nc(N)c(C#N)c(c3ccc(OC)c(OC)c3)c2c1N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F07 compound treatment 623976.0 65100.0 0.29 659460.0 107000.0 0.53 0.5804 0.9606 1138679 ChemDiv1_011733 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F08 compound treatment 651349.0 92500.0 0.41 629439.0 76800.0 0.38 0.5619 0.9991 1944683 ChemDiv1_011734 Brc1ccc2nc(nc(c3ccccc3)c2c1)N4CCNCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F09 compound treatment 659966.0 101000.0 0.45 672473.0 120000.0 0.59 0.7399 0.9911 1575700 ChemDiv1_011735 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)CCC4CCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F10 compound treatment 640134.0 81300.0 0.36 658641.0 106000.0 0.53 0.6286 0.984 1975772 ChemDiv1_011736 CCOC(=O)c1c(CBr)n(C)c2cc(Br)c(OC(=O)C)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F11 compound treatment 672693.0 114000.0 0.51 715920.0 163000.0 0.81 0.9323 0.9752 1975773 ChemDiv1_011737 CC1CCN(CN2C(=O)/C(=C\c3ccccc3Cl)/SC2=S)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F12 compound treatment 691918.0 133000.0 0.6 694218.0 142000.0 0.7 0.9172 0.9967 1975774 ChemDiv1_011738 COc1cc(SC#N)ccc1N/C=C\2/C(=NN(C2=O)c3ccc(Br)cc3)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F13 compound treatment 667938.0 109000.0 0.49 697293.0 145000.0 0.72 0.852 0.9825 1588761 ChemDiv1_011739 O=C(CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1)C3(CC4CC5CC(C4)C3)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F14 compound treatment 657963.0 99100.0 0.44 684253.0 132000.0 0.65 0.7748 0.9824 1553268 ChemDiv1_011740 Cc1ccc(cc1Br)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F15 compound treatment 685975.0 127000.0 0.57 712884.0 160000.0 0.79 0.9637 0.9867 1975775 ChemDiv1_011741 CCCC1=C(C(C(=C(N)O1)C#N)c2c(C)nn(c2Cl)c3ccccc3)C(=O)OCC 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F16 compound treatment 660092.0 101000.0 0.45 686219.0 134000.0 0.66 0.7884 0.983 1975776 ChemDiv1_011742 CCOc1ccc(cc1)N2C(=O)C(C)SC23C(=O)N(CN4CCc5ccccc5C4)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F17 compound treatment 674415.0 116000.0 0.52 684816.0 132000.0 0.65 0.8288 0.9932 1426707 ChemDiv1_011743 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccc(Cl)c(Cl)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F18 compound treatment 665979.0 107000.0 0.48 664575.0 112000.0 0.55 0.7312 0.9974 1655342 ChemDiv1_011744 CCOc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)ccc1OCc5ccc(F)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F19 compound treatment 645919.0 87100.0 0.39 681893.0 129000.0 0.64 0.7284 0.9717 1403965 ChemDiv1_011745 CCOC(=O)C1=C(N)Oc2c(C1c3ccc(Cl)c(Cl)c3)c(=O)oc4ccccc24 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F20 compound treatment 645363.0 86500.0 0.39 663273.0 111000.0 0.55 0.6614 0.9856 1975777 ChemDiv1_011746 CC(C)(C)c1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(Br)cc43)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F21 compound treatment 673811.0 115000.0 0.51 677759.0 125000.0 0.62 0.8022 0.9957 1196561 ChemDiv1_011747 CCOC(=O)C1=C(N=c2sc(=Cc3cccnc3)c(=O)n2C1c4ccc(OC)c(OC)c4)c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F22 compound treatment 636154.0 77300.0 0.35 642090.0 89400.0 0.44 0.5581 0.9925 1431776 ChemDiv1_011748 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)N4CCOCC4)c(OCC)c3)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F23 mock treatment 645224.0 86400.0 0.39 651489.0 98800.0 0.49 0.6197 0.9932 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 F24 mock treatment 505950.0 -52900.0 -0.24 480542.0 -72100.0 -0.36 -0.4199 -0.98 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G01 compound treatment 567849.0 9020.0 0.04 607712.0 55100.0 0.27 0.2214 0.803 1198349 ChemDiv1_011749 Clc1ccc(cc1Cl)C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G02 compound treatment 592206.0 33400.0 0.15 618183.0 65500.0 0.32 0.3352 0.9379 1975778 ChemDiv1_011750 Clc1ccc(OCC(=O)NN2C(=O)C3C4C=CC(C3C2=O)C54CC5)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G03 compound treatment 589654.0 30800.0 0.14 648581.0 95900.0 0.48 0.4336 0.8762 1469692 ChemDiv1_011751 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G04 compound treatment 617640.0 58800.0 0.26 634347.0 81700.0 0.4 0.4723 0.9783 1975779 ChemDiv1_011752 [O-][N+](=O)c1ccc(cc1)C2NCCc3c2[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G05 compound treatment 639888.0 81100.0 0.36 663205.0 111000.0 0.55 0.6439 0.98 1565551 ChemDiv1_011753 Nc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G06 compound treatment 643297.0 84500.0 0.38 648817.0 96200.0 0.48 0.6042 0.9934 1975780 ChemDiv1_011754 COc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G07 compound treatment 669523.0 111000.0 0.5 693245.0 141000.0 0.7 0.8429 0.9861 1942681 ChemDiv1_011755 Cc1ccc2c(nc3sc(=Cc4ccc(o4)c5cccc(c5)C(F)(F)F)c(=O)n32)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G08 compound treatment 647150.0 88300.0 0.4 666812.0 114000.0 0.57 0.6795 0.9847 1299334 ChemDiv1_011756 CCCCc1ccc(C#N)c(SCc2c(C(=O)OCC)c3cc(OC(=O)C)c(Br)cc3n2C)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G09 compound treatment 663090.0 104000.0 0.47 656861.0 104000.0 0.52 0.6951 0.9987 1595176 ChemDiv1_011757 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCC(=O)Nc5cc(C)ccc5C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G10 compound treatment 660657.0 102000.0 0.46 656458.0 104000.0 0.51 0.686 0.9982 1879066 ChemDiv1_011758 Clc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G11 compound treatment 664099.0 105000.0 0.47 662044.0 109000.0 0.54 0.7164 0.9976 1975781 ChemDiv1_011759 CCc1ccc(cc1)C2(O)CC(=NN2C(=O)c3ccccn3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G12 compound treatment 651538.0 92700.0 0.41 668165.0 116000.0 0.57 0.6981 0.9875 1853273 ChemDiv1_011760 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(cc4)[N+](=O)[O-])c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G13 compound treatment 830701.0 272000.0 1.22 878290.0 326000.0 1.61 2.0012 0.9903 1629609 ChemDiv1_011761 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(OC)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G14 compound treatment 661109.0 102000.0 0.46 691110.0 138000.0 0.69 0.8088 0.9807 1674300 ChemDiv1_011762 CCOC(=O)c1c(CSc2ccccc2)n(c3ccccc3)c4cc(Br)c(O)cc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G15 compound treatment 677944.0 119000.0 0.53 716505.0 164000.0 0.81 0.951 0.9792 1950280 ChemDiv1_011763 COc1ccccc1NC(=O)CSc2nnc(NC(=O)CSc3nnc4n(N)cnn34)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G16 compound treatment 666259.0 107000.0 0.48 696614.0 144000.0 0.71 0.8444 0.9816 1224819 ChemDiv1_011764 CC(C)(C)NC(=O)CSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G17 compound treatment 676182.0 117000.0 0.53 712116.0 159000.0 0.79 0.9301 0.9803 1975782 ChemDiv1_011765 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CN3CC(=O)NC(=O)C3)cc2)n1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G18 compound treatment 658762.0 99900.0 0.45 688584.0 136000.0 0.67 0.7925 0.9803 1975783 ChemDiv1_011766 [O-][N+](=O)c1cccc(NC(=O)CSc2nn3c(SCC(=O)Nc4cccc(c4)[N+](=O)[O-])nnc3s2)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G19 compound treatment 690951.0 132000.0 0.59 704740.0 152000.0 0.75 0.951 0.9928 1975784 ChemDiv1_011767 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(Br)s2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G20 compound treatment 628705.0 69900.0 0.31 688673.0 136000.0 0.67 0.6977 0.9391 1975785 ChemDiv1_011768 Clc1ccc(cc1)c2nn(cc2C=c3sc4nc5ccccc5n4c3=O)c6ccccc6 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G21 compound treatment 651872.0 93000.0 0.42 667859.0 115000.0 0.57 0.6981 0.988 1975786 ChemDiv1_011769 Clc1ccc2[nH]c3c(cc(Nc4ccccc4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G22 compound treatment 625225.0 66400.0 0.3 651217.0 98600.0 0.49 0.5554 0.9717 1975787 ChemDiv1_011770 Brc1ccc(NC(=O)CSc2nnc(NC(=O)CN3CCCCC3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G23 mock treatment 637242.0 78400.0 0.35 624165.0 71500.0 0.35 0.4987 1.0 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 G24 mock treatment 507583.0 -51200.0 -0.23 501176.0 -51500.0 -0.25 -0.3425 -0.9986 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H01 compound treatment 545109.0 -13700.0 -0.06 576712.0 24100.0 0.12 0.0409 0.3047 1546956 ChemDiv1_011771 COc1cc(ccc1OC(=O)Nc2cccc(Cl)c2)C3C4=C(CC(C)(C)CC4=O)OC5=C3C(=O)CC(C)(C)C5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H02 compound treatment 599161.0 40300.0 0.18 611557.0 58900.0 0.29 0.334 0.9733 1975788 ChemDiv1_011772 CC(=O)/N=C/1\S/C(=C\c2cccc(F)c2)/C(=O)N1c3ccc(C)c(C)c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H03 compound treatment 611774.0 52900.0 0.24 626773.0 74100.0 0.37 0.4272 0.9775 1975789 ChemDiv1_011773 Clc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC(=O)Nc3ccc(Br)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H04 compound treatment 584181.0 25300.0 0.11 616083.0 63400.0 0.31 0.3025 0.9052 1975790 ChemDiv1_011774 Clc1cccc(Cl)c1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5ccccc5)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H05 compound treatment 646149.0 87300.0 0.39 642474.0 89800.0 0.45 0.5911 0.9979 1975791 ChemDiv1_011775 COc1ccc(cc1OC)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4cc(ccc4C)[N+](=O)[O-])C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H06 compound treatment 615207.0 56400.0 0.25 614560.0 61900.0 0.31 0.3953 0.9953 1327630 ChemDiv1_011776 CC1CCc2c(C1)sc3nc(C)oc(=O)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H07 compound treatment 664580.0 106000.0 0.47 664063.0 111000.0 0.55 0.725 0.9971 1403060 ChemDiv1_011777 CCSc1nnc(NC(=O)CSc2nnc3c4cc(Br)ccc4n(C)c3n2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H08 compound treatment 654508.0 95700.0 0.43 651877.0 99200.0 0.49 0.6504 0.9976 1975792 ChemDiv1_011778 CC(=O)c1ccc(NC(=O)CSc2nnc(SCC(=O)Nc3ccc(cc3)C(=O)C)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H09 compound treatment 662094.0 103000.0 0.46 644177.0 91500.0 0.45 0.6475 1.0 1975793 ChemDiv1_011779 COc1ccc(/C=C\2/S/C(=N/c3ccc(Cl)c(c3)C(=O)O)/NC2=O)cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H10 compound treatment 644293.0 85500.0 0.38 631107.0 78500.0 0.39 0.5454 1.0 1782659 ChemDiv1_011780 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccccc4[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H11 compound treatment 636406.0 77600.0 0.35 665818.0 113000.0 0.56 0.642 0.9735 1947516 ChemDiv1_011781 COc1ccc(/N=C\2/SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H12 compound treatment 634018.0 75200.0 0.34 644225.0 91600.0 0.45 0.5588 0.9892 1975794 ChemDiv1_011782 CC/1=NN(C(=O)\C1=C/Nc2ccc3nc(C)[nH]c3c2)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H13 compound treatment 704184.0 145000.0 0.65 674518.0 122000.0 0.6 0.887 0.9993 1975795 ChemDiv1_011783 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(OC)c(CSc3ccccn3)c2)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H14 compound treatment 638364.0 79500.0 0.36 672716.0 120000.0 0.59 0.6723 0.9699 1175806 ChemDiv1_011784 Clc1ccc(Nc2nc3nonc3nc2N4CCCCC4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H15 compound treatment 729259.0 170000.0 0.76 729391.0 177000.0 0.88 1.1586 0.9976 1975796 ChemDiv1_011785 CC(NC(=O)CSc1nc(C)cc(c1C#N)C(F)(F)F)C2(CC3CC4CC(C3)C2)C4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H16 compound treatment 661363.0 103000.0 0.46 666462.0 114000.0 0.56 0.7232 0.9948 1315263 ChemDiv1_011786 Cn1cnnc1SCC(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc45)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H17 compound treatment 686072.0 127000.0 0.57 673515.0 121000.0 0.6 0.8262 0.9997 1234681 ChemDiv1_011787 O=C(CSc1nc2ccccc2[nH]1)Nc3nc4c(ccc5ccccc45)s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H18 compound treatment 658974.0 100000.0 0.45 664992.0 112000.0 0.56 0.7105 0.9942 1247852 ChemDiv1_011788 Cc1cc(C)c2nc3sc(=Cc4cccc(OCc5ccc(Cl)cc5)c4)c(=O)n3c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H19 compound treatment 674079.0 115000.0 0.52 690996.0 138000.0 0.69 0.8494 0.9902 1975797 ChemDiv1_011789 Brc1ccccc1CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H20 compound treatment 632347.0 73500.0 0.33 642227.0 89600.0 0.44 0.5465 0.9892 1364996 ChemDiv1_011790 CCCc1n[nH]c2OC(=C(C(=O)OCC)C3(C(=O)Nc4ccc(Br)cc43)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H21 compound treatment 713379.0 155000.0 0.69 735637.0 183000.0 0.91 1.1302 0.9911 1402170 ChemDiv1_011791 CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(o3)N4CCCCC4)c(=O)n2C1c5cccc(OC)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H22 compound treatment 630628.0 71800.0 0.32 655531.0 103000.0 0.51 0.5877 0.9753 1584788 ChemDiv1_011792 CCOc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H23 mock treatment 637790.0 79000.0 0.35 636671.0 84000.0 0.42 0.5443 0.9967 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 H24 mock treatment 502547.0 -56300.0 -0.25 497732.0 -54900.0 -0.27 -0.3705 -0.9993 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I01 compound treatment 545852.0 -13000.0 -0.06 590044.0 37400.0 0.19 0.0899 0.4631 1975798 ChemDiv1_011793 Brc1ccccc1C(=O)N2CCN(CC2)C3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I02 compound treatment 580505.0 21700.0 0.1 606025.0 53400.0 0.26 0.2556 0.9074 1975799 ChemDiv1_011794 OC1(CC(=NN1C(=O)c2ccccn2)C(F)(F)F)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I03 compound treatment 618734.0 59900.0 0.27 625712.0 73100.0 0.36 0.4456 0.9891 1222523 ChemDiv1_011795 Fc1cccc(Cl)c1COc2ccc(Cl)cc2C=c3sc4nc5ccccc5n4c3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I04 compound treatment 585550.0 26700.0 0.12 618341.0 65700.0 0.33 0.3147 0.9076 1192349 ChemDiv1_011796 Fc1ccc(cc1)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I05 compound treatment 628365.0 69500.0 0.31 643971.0 91300.0 0.45 0.54 0.9833 1975800 ChemDiv1_011797 Cc1ccc(cc1C)N2C(Nc3ccccc3C2=O)c4ccc(OCc5ccccc5Cl)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I06 compound treatment 619565.0 60700.0 0.27 643898.0 91300.0 0.45 0.5119 0.9704 1975801 ChemDiv1_011798 OC1(CC(=NN1C(=O)c2cccc(Cl)c2)C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I07 compound treatment 1999852.0 1440000.0 6.45 1766887.0 1210000.0 6.02 8.8146 0.9994 1666423 ChemDiv1_011799 Cc1ccc2c(nc3sc(=Cc4ccc(o4)c5ccccc5C(=O)O)c(=O)n32)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I08 compound treatment 652477.0 93600.0 0.42 667615.0 115000.0 0.57 0.6991 0.9886 1612514 ChemDiv1_011800 CCOC(=O)c1c(CSc2nc(C)c(CC)c(C)c2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I09 compound treatment 662640.0 104000.0 0.46 675481.0 123000.0 0.61 0.7589 0.9911 1728120 ChemDiv1_011801 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cc6cc(Br)ccc6o5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I10 compound treatment 608874.0 50000.0 0.22 649367.0 96700.0 0.48 0.4972 0.94 1880183 ChemDiv1_011802 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(Cl)c(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I11 compound treatment 656659.0 97800.0 0.44 704107.0 151000.0 0.75 0.8402 0.9671 1259510 ChemDiv1_011803 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(Cl)c4Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I12 compound treatment 645764.0 86900.0 0.39 652525.0 99900.0 0.49 0.625 0.9929 1975802 ChemDiv1_011804 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccc4OCOc4c3)N)c5cccc(Cl)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I13 compound treatment 662435.0 104000.0 0.46 673910.0 121000.0 0.6 0.7527 0.9918 1183924 ChemDiv1_011805 CC(C)OC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I14 compound treatment 664095.0 105000.0 0.47 665157.0 113000.0 0.56 0.7273 0.9965 1975803 ChemDiv1_011806 CCOC(=O)/C=C(\C)/N1N=C(CC1c2ccc(OC)cc2)c3cccc(c3)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I15 compound treatment 672257.0 113000.0 0.51 691764.0 139000.0 0.69 0.8463 0.9887 1975804 ChemDiv1_011807 Nn1cnn2c(SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(Cl)c(Cl)c4)s3)nnc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I16 compound treatment 661581.0 103000.0 0.46 664602.0 112000.0 0.55 0.7174 0.9957 1621849 ChemDiv1_011808 CC(C)c1ccc(cc1)N2C(=O)CSC23C(=O)Nc4ccccc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I17 compound treatment 664136.0 105000.0 0.47 683521.0 131000.0 0.65 0.7918 0.9877 1730354 ChemDiv1_011809 CCOC(=O)c1c(CSc2nc(C)ccc2C#N)n(C)c3cc(Br)c(OC(=O)C)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I18 compound treatment 649463.0 90600.0 0.41 672248.0 120000.0 0.59 0.7058 0.9829 1975805 ChemDiv1_011810 FC(F)(F)c1cccc(c1)N2C(=O)CSC23C(=O)N(CN4CCCCC4)c5ccccc53 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I19 compound treatment 646050.0 87200.0 0.39 688756.0 136000.0 0.67 0.7529 0.9662 1975806 ChemDiv1_011811 [O-][N+](=O)c1cc(cc([N+](=O)[O-])c1Sc2nc3ccccc3[nH]2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I20 compound treatment 635258.0 76400.0 0.34 649223.0 96600.0 0.48 0.5802 0.9865 1928354 ChemDiv1_011812 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3cccc(c3)[N+](=O)[O-])c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I21 compound treatment 652790.0 94000.0 0.42 691640.0 139000.0 0.69 0.7843 0.972 1201916 ChemDiv1_011813 CCOC(=O)c1sc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCCC3)c(C(=O)OCC)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I22 compound treatment 633456.0 74600.0 0.33 652834.0 100000.0 0.5 0.5872 0.9814 1273619 ChemDiv1_011814 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)c4ccc(C)cc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I23 mock treatment 632994.0 74200.0 0.33 648359.0 95700.0 0.47 0.57 0.9848 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 I24 mock treatment 538907.0 -19900.0 -0.09 498485.0 -54200.0 -0.27 -0.2528 -0.8941 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J01 compound treatment 561713.0 2880.0 0.01 591164.0 38500.0 0.19 0.1441 0.7532 1245252 ChemDiv1_011815 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(OCC(=O)N)cc4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J02 compound treatment 1787051.0 1230000.0 5.5 1793896.0 1240000.0 6.15 8.2356 0.9984 1440239 ChemDiv1_011816 COc1cc(C=c2sc3nc4cc(C)c(C)cc4n3c2=O)cc(Br)c1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J03 compound treatment 635622.0 76800.0 0.34 651709.0 99100.0 0.49 0.5901 0.9848 1321872 ChemDiv1_011817 CCN(CC)C(=O)CSc1nc2ccccc2n1C(=O)OCC(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J04 compound treatment 599943.0 41100.0 0.18 616590.0 63900.0 0.32 0.3541 0.9666 1975807 ChemDiv1_011818 CC(C)c1ccc(cc1)N2C(=O)CSC23C(=O)N(CN4CCOCC4)c5ccccc53 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J05 compound treatment 659284.0 100000.0 0.45 633431.0 80800.0 0.4 0.601 0.9983 1633909 ChemDiv1_011819 COc1ccc(cc1)C2C(=C(N)N(C3=C2C(=O)CC(C)(C)C3)c4ccc(OC)cc4OC)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J06 compound treatment 638697.0 79900.0 0.36 604396.0 51800.0 0.26 0.4341 0.9867 1975808 ChemDiv1_011820 COc1ccc(cc1)c2cc(n3nc(C(=O)NCc4cccnc4)c(Cl)c3n2)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J07 compound treatment 678884.0 120000.0 0.54 664979.0 112000.0 0.56 0.7735 0.9998 1975809 ChemDiv1_011821 COc1ccc(N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J08 compound treatment 666715.0 108000.0 0.48 649582.0 96900.0 0.48 0.681 1.0 1420846 ChemDiv1_011822 Cc1ccc(N2C(=O)CSC23C(=O)Nc4ccccc43)c(C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J09 compound treatment 648633.0 89800.0 0.4 655397.0 103000.0 0.51 0.6442 0.9932 1493101 ChemDiv1_011823 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nncn4C)cc3s2)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J10 compound treatment 659740.0 101000.0 0.45 648703.0 96100.0 0.48 0.6559 0.9997 1975810 ChemDiv1_011824 CCCCC1=NN(C(=O)c2ccc(cc2)[N+](=O)[O-])C(O)(C1)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J11 compound treatment 664640.0 106000.0 0.47 683376.0 131000.0 0.65 0.7929 0.9882 1975811 ChemDiv1_011825 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4cccs4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J12 compound treatment 627997.0 69200.0 0.31 646253.0 93600.0 0.46 0.5468 0.9807 1431326 ChemDiv1_011826 COc1ccc(OC)c(Nc2nc3nonc3nc2Nc4cccc(Cl)c4)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J13 compound treatment 692719.0 134000.0 0.6 693863.0 141000.0 0.7 0.9185 0.997 1975812 ChemDiv1_011827 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(F)cc2F)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J14 compound treatment 672304.0 113000.0 0.51 648804.0 96200.0 0.48 0.696 0.9995 1716194 ChemDiv1_011828 Cc1ccc(Nc2nc3nonc3nc2Nc4ccccc4F)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J15 compound treatment 711034.0 152000.0 0.68 709743.0 157000.0 0.78 1.0321 0.9978 1975813 ChemDiv1_011829 COC(=O)c1ccccc1NC(=O)CSc2nnc(SCC(=O)Nc3ccccc3C(=O)OC)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J16 compound treatment 662280.0 103000.0 0.46 674287.0 122000.0 0.6 0.7535 0.9915 1275700 ChemDiv1_011830 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(C)c3cc(Br)c(OC)cc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J17 compound treatment 680220.0 121000.0 0.54 653573.0 101000.0 0.5 0.7378 0.9991 1510750 ChemDiv1_011831 Fc1ccccc1Nc2nc3nonc3nc2N4CCCCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J18 compound treatment 677764.0 119000.0 0.53 636754.0 84100.0 0.42 0.6711 0.9926 1409948 ChemDiv1_011832 COc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCC(=O)Nc5ccc(C)c(C)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J19 compound treatment 693246.0 134000.0 0.6 680325.0 128000.0 0.63 0.8727 0.9997 1575848 ChemDiv1_011833 CC(CCc1ccccc1)Nc2nc(Cl)nc(NCCN3CCOCC3)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J20 compound treatment 667038.0 108000.0 0.48 637723.0 85100.0 0.42 0.6405 0.9976 1975814 ChemDiv1_011834 Cc1c(NC(=O)CSc2nc3ccc(NC(=O)c4ccc(Cl)cc4)cc3s2)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J21 compound treatment 658367.0 99500.0 0.45 660888.0 108000.0 0.54 0.6942 0.9958 1975815 ChemDiv1_011835 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)Nc4ccc(cc43)[N+](=O)[O-])c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J22 compound treatment 641632.0 82800.0 0.37 652565.0 99900.0 0.5 0.6121 0.9898 1210871 ChemDiv1_011836 Cc1n[nH]c2OC(=C(C#N)C3(C(=O)N(CCc4ccccc4)c5ccccc53)c12)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J23 mock treatment 652009.0 93200.0 0.42 650264.0 97600.0 0.48 0.6369 0.9973 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 J24 mock treatment 534024.0 -24800.0 -0.11 200866.0 -352000.0 -1.74 -1.3107 -0.7506 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K01 compound treatment 546604.0 -12200.0 -0.05 598392.0 45800.0 0.23 0.1216 0.5213 1975816 ChemDiv1_011837 CCCCOc1ccc(cc1)C(=O)Nc2ccc3nc(SCC(=O)NCC4CCCO4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K02 compound treatment 574377.0 15500.0 0.07 604552.0 51900.0 0.26 0.231 0.8673 1975817 ChemDiv1_011838 Cc1nnc(NC(=O)COC(=O)CSc2nc(cc(n2)c3ccccc3)c4ccccc4)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K03 compound treatment 598328.0 39500.0 0.18 621933.0 69300.0 0.34 0.3677 0.9524 1942760 ChemDiv1_011839 C/N=C\1/S/C(=C\c2cc3OCOc3cc2Br)/C(=O)N1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K04 compound treatment 587078.0 28200.0 0.13 614658.0 62000.0 0.31 0.3066 0.923 1143177 ChemDiv1_011840 Clc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K05 compound treatment 624025.0 65200.0 0.29 633140.0 80500.0 0.4 0.4883 0.9882 1336178 ChemDiv1_011841 O=C1N(CN2CCN(CC2)c3ccccc3)c4ccccc4C51OCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K06 compound treatment 629459.0 70600.0 0.32 625963.0 73300.0 0.36 0.4804 0.9976 1975818 ChemDiv1_011842 OC1(CC(=NN1C(=O)c2ccccc2[N+](=O)[O-])C(F)(F)F)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K07 compound treatment 634259.0 75400.0 0.34 629443.0 76800.0 0.38 0.5078 0.9982 1473372 ChemDiv1_011843 COc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K08 compound treatment 617669.0 58800.0 0.26 632820.0 80200.0 0.4 0.4671 0.9801 1975819 ChemDiv1_011844 COc1cc(cc(OC)c1OC)c2c(C#N)c(N)nc(SCC(=O)O)c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K09 compound treatment 648747.0 89900.0 0.4 640763.0 88100.0 0.44 0.5933 0.9992 1442381 ChemDiv1_011845 Cc1nnc(SCC(=O)Nc2ccc3nc(SCC(=O)NC4CCCCC4)sc3c2)s1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K10 compound treatment 621436.0 62600.0 0.28 615003.0 62400.0 0.31 0.4166 0.9988 1975820 ChemDiv1_011846 [O-][N+](=O)c1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5cccc(Br)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K11 compound treatment 649848.0 91000.0 0.41 667615.0 115000.0 0.57 0.6908 0.9865 1211362 ChemDiv1_011847 CCOc1ccc2nc(SCC(=O)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K12 compound treatment 623444.0 64600.0 0.29 657160.0 105000.0 0.52 0.5706 0.9622 1975821 ChemDiv1_011848 Cc1ccc(/C=C/2\SC(=S)N(CN3CCCCCC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K13 compound treatment 652790.0 94000.0 0.42 649000.0 96400.0 0.48 0.6349 0.998 1736383 ChemDiv1_011849 CCOc1cc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(Br)cc1O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K14 compound treatment 644849.0 86000.0 0.39 646772.0 94100.0 0.47 0.602 0.9955 1566463 ChemDiv1_011850 O=C(Cc1cccc2ccccc12)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K15 compound treatment 669979.0 111000.0 0.5 695614.0 143000.0 0.71 0.8526 0.9851 1432216 ChemDiv1_011851 Clc1ccc(OCc2nnc(NC(=O)c3cc(ccc3Cl)S(=O)(=O)N4CCOCC4)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K16 compound treatment 646144.0 87300.0 0.39 657456.0 105000.0 0.52 0.6435 0.9902 1302573 ChemDiv1_011852 COc1ccc(cc1OC)c2c(C#N)c(N)nc3sc(C(=O)OCc4ccccc4)c(N)c23 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K17 compound treatment 655682.0 96800.0 0.43 657376.0 105000.0 0.52 0.6734 0.996 1289812 ChemDiv1_011853 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(C)cc3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K18 compound treatment 625655.0 66800.0 0.3 659546.0 107000.0 0.53 0.586 0.9634 1664153 ChemDiv1_011854 CC1(C)CC(=O)C2=C(C1)OC3=C(C(=O)CC(C)(C)C3)C42C(=O)Nc5ccccc54 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K19 compound treatment 652326.0 93500.0 0.42 627698.0 75100.0 0.37 0.5588 0.9983 1568883 ChemDiv1_011855 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccccc5C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K20 compound treatment 631958.0 73100.0 0.33 631152.0 78500.0 0.39 0.5065 0.9963 1385329 ChemDiv1_011856 CCOc1cc(C=c2sc3nc4ccccc4n3c2=O)ccc1OCc5ccccc5F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K21 compound treatment 650641.0 91800.0 0.41 660010.0 107000.0 0.53 0.6667 0.9919 1975822 ChemDiv1_011857 Cc1ccc(cc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)Nc3cccc(c3)C(=O)O)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K22 compound treatment 636162.0 77300.0 0.35 647493.0 94900.0 0.47 0.577 0.9887 1603282 ChemDiv1_011858 COc1ccc(OC)c(c1)N2C(=C(C#N)C(C3=C2CCCC3=O)c4ccc(OC)c(O)c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K23 mock treatment 630352.0 71500.0 0.32 626427.0 73800.0 0.37 0.4848 0.9978 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 K24 mock treatment 506337.0 -52500.0 -0.23 490885.0 -61800.0 -0.31 -0.3825 -0.9915 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L01 compound treatment 571997.0 13200.0 0.06 610110.0 57500.0 0.28 0.243 0.8358 1566192 ChemDiv1_011859 COc1ccc(N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc(F)cc4)N)c(OC)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L02 compound treatment 587053.0 28200.0 0.13 607498.0 54900.0 0.27 0.2815 0.9393 1975823 ChemDiv1_011860 CN1C(=O)C(=c2sc3=NC4(N(C)C(=O)N(C)C4(Nn3c2=O)c5ccccc5)c6ccccc6)c7ccccc17 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L03 compound treatment 631102.0 72300.0 0.32 614536.0 61900.0 0.31 0.4456 0.9996 1140976 ChemDiv1_011861 CCOC(=O)C1=C(C)OC(=C(C#N)C1c2cc(OC)ccc2OC)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L04 compound treatment 609463.0 50600.0 0.23 604923.0 52300.0 0.26 0.3434 0.9978 1975824 ChemDiv1_011862 FC(F)(F)c1cccc(c1)N2C(=O)c3ccccc3NC24C(=O)N(Cc5c(Cl)cccc5Cl)c6ccccc64 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L05 compound treatment 642847.0 84000.0 0.38 644255.0 91600.0 0.45 0.5868 0.9956 1462456 ChemDiv1_011863 COC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)CSc4nnc(C)s4)cc3s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L06 compound treatment 643881.0 85000.0 0.38 647255.0 94600.0 0.47 0.6006 0.9947 1975825 ChemDiv1_011864 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C/Nc3ccc(cc3)S(=O)(=O)Nc4nccs4)/C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L07 compound treatment 657631.0 98800.0 0.44 646634.0 94000.0 0.47 0.642 0.9997 1455897 ChemDiv1_011865 CC1CC(N(C(=O)c2cccc(F)c2)c3ccccc3)c4ccccc4N1C(=O)c5cccc(F)c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L08 compound treatment 635873.0 77000.0 0.34 612263.0 59600.0 0.3 0.4527 0.997 1782210 ChemDiv1_011866 CC1=NN(C(=O)c2cccc(c2)[N+](=O)[O-])C(O)(C1)c3ccc(Cl)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L09 compound treatment 658191.0 99400.0 0.44 626504.0 73900.0 0.37 0.5732 0.9953 1975826 ChemDiv1_011867 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L10 compound treatment 773723.0 215000.0 0.96 719723.0 167000.0 0.83 1.2655 0.9972 1270349 ChemDiv1_011868 COC(=O)c1ccc(cc1)c2c(C#N)c(N)n3c4ccccc4nc3c2C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L11 compound treatment 652777.0 93900.0 0.42 638077.0 85400.0 0.42 0.5966 1.0 1975827 ChemDiv1_011869 CN(C)N/1C(=O)/C(=C\c2cc3OCOc3cc2[N+](=O)[O-])/S\C1=N/c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L12 compound treatment 641368.0 82500.0 0.37 649743.0 97100.0 0.48 0.6014 0.9915 1365100 ChemDiv1_011870 Cn1ccnc1SCC(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(F)cc4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L13 compound treatment 659037.0 100000.0 0.45 656320.0 104000.0 0.51 0.6803 0.9977 1694028 ChemDiv1_011871 COc1ccc(cc1OCc2ccccc2)C3C(=C(N)Oc4cc(C)oc(=O)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L14 compound treatment 656749.0 97900.0 0.44 641829.0 89200.0 0.44 0.6223 1.0 1432148 ChemDiv1_011872 S=c1sc2c(ncnc2n1c3ccccc3)N4CCCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L15 compound treatment 697072.0 138000.0 0.62 692201.0 140000.0 0.69 0.9264 0.9985 1975828 ChemDiv1_011873 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2nc3ccccc3s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L16 compound treatment 652529.0 93700.0 0.42 654073.0 101000.0 0.5 0.6519 0.996 1975829 ChemDiv1_011874 Nc1ccc2[nH]c(SCc3nc4ccccc4c(=O)n3c5cccc(c5)C(F)(F)F)nc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L17 compound treatment 685824.0 127000.0 0.57 686141.0 133000.0 0.66 0.8696 0.9972 1261618 ChemDiv1_011875 Cc1cc2nc3sc(=Cc4cc(Cl)ccc4OCc5ccccc5)c(=O)n3c2cc1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L18 compound treatment 657914.0 99100.0 0.44 647785.0 95100.0 0.47 0.6469 0.9995 1975830 ChemDiv1_011876 FC(F)(F)c1cccc(c1)N2C(=O)CSC23C(=O)N(CN4CCN(CC4)c5ccccc5)c6ccccc63 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L19 compound treatment 668850.0 110000.0 0.49 657994.0 105000.0 0.52 0.7173 0.9996 1611824 ChemDiv1_011877 Fc1ccccc1CN2C(=O)C3(Nc4ccccc4C(=O)N3c5ccccc5)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L20 compound treatment 647363.0 88500.0 0.4 651037.0 98400.0 0.49 0.6249 0.9947 1723595 ChemDiv1_011878 COc1ccc(cc1)c2csc(NC(=O)c3cc4cc(Br)ccc4oc3=O)n2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L21 compound treatment 665377.0 107000.0 0.48 670823.0 118000.0 0.59 0.7512 0.9948 1929226 ChemDiv1_011879 C=CCc1cccc2cc(C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34)c(=O)oc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L22 compound treatment 670632.0 112000.0 0.5 647510.0 94900.0 0.47 0.6862 0.9995 1652351 ChemDiv1_011880 NC1=C(C#N)C(C2=C(CCCC2=O)O1)c3cc(Cl)cc(Cl)c3OC(=O)N4CCOCC4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L23 mock treatment 655117.0 96300.0 0.43 646872.0 94200.0 0.47 0.6348 0.9992 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 L24 mock treatment 508389.0 -50400.0 -0.23 516964.0 -35700.0 -0.18 -0.2846 -0.9927 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M01 compound treatment 609952.0 51100.0 0.23 662394.0 110000.0 0.54 0.5463 0.926 1975831 ChemDiv1_011881 COc1ccc(/C=C\2/SC(=S)N(CN3CCCCC3C)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M02 compound treatment 567495.0 8660.0 0.04 589305.0 36700.0 0.18 0.1558 0.8392 1467697 ChemDiv1_011882 CCC(=O)Nc1ccc2nc(SCC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M03 compound treatment 590373.0 31500.0 0.14 610160.0 57500.0 0.28 0.3013 0.9475 1477109 ChemDiv1_011883 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCc5ccc(Cl)c(Cl)c5)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M04 compound treatment 582176.0 23300.0 0.1 588223.0 35600.0 0.18 0.1985 0.9688 1975832 ChemDiv1_011884 COc1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(cc5)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M05 compound treatment 618948.0 60100.0 0.27 617427.0 64800.0 0.32 0.4172 0.9962 1975833 ChemDiv1_011885 Clc1ccc(Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26)cc1Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M06 compound treatment 591973.0 33100.0 0.15 606780.0 54100.0 0.27 0.2945 0.961 1135740 ChemDiv1_011886 COc1ccc(OC)c(c1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccc5OCOc5c4)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M07 compound treatment 620165.0 61300.0 0.27 638499.0 85900.0 0.43 0.4949 0.9776 1975834 ChemDiv1_011887 Cc1c(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c(=O)n(C)n1c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M08 compound treatment 3616353.0 3060000.0 13.69 3796676.0 3240000.0 16.07 21.0413 0.9968 1975835 ChemDiv1_011888 CN(C)c1ccc(/C=C\2/SC(=S)N(CN3CCCC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M09 compound treatment 623754.0 64900.0 0.29 621712.0 69100.0 0.34 0.4474 0.9967 1975836 ChemDiv1_011889 O=C(CSc1nc2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2s1)NC5CC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M10 compound treatment 614212.0 55400.0 0.25 621796.0 69200.0 0.34 0.4175 0.9874 1975837 ChemDiv1_011890 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccccc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M11 compound treatment 650888.0 92100.0 0.41 653369.0 101000.0 0.5 0.6442 0.9955 1452689 ChemDiv1_011891 O=C1N(CN2CCC(Cc3ccccc3)CC2)c4ccccc4C51OCCO5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M12 compound treatment 644337.0 85500.0 0.38 641330.0 88700.0 0.44 0.5813 0.9976 1975838 ChemDiv1_011892 CC(C)c1ccc(/C=C\2/SC(=S)N(CN3CCCC3)C2=O)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M13 compound treatment 640559.0 81700.0 0.37 637769.0 85100.0 0.42 0.5569 0.9975 1975839 ChemDiv1_011893 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4cccc(Br)c4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M14 compound treatment 625318.0 66500.0 0.3 622707.0 70100.0 0.35 0.4559 0.9971 1975840 ChemDiv1_011894 COc1ccc(cc1CSc2nc3ccc(NC(=O)C)cc3s2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M15 compound treatment 607804.0 49000.0 0.22 667111.0 114000.0 0.57 0.556 0.9145 1975841 ChemDiv1_011895 COc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=C(C3c4ccc(O)cc4)C(=O)OCCOc5ccccc5)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M16 compound treatment 642812.0 84000.0 0.38 628565.0 75900.0 0.38 0.5318 1.0 1975842 ChemDiv1_011896 ClC1=CCC2C(C1)C(=O)N(CN(CN3C(=O)C4CC=C(Cl)CC4C3=O)C5CCCCC5)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M17 compound treatment 648908.0 90100.0 0.4 663848.0 111000.0 0.55 0.6747 0.9882 1163691 ChemDiv1_011897 Clc1ccc(C2Nc3ccccc3C(=O)N2c4ccc(I)cc4)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M18 compound treatment 626997.0 68200.0 0.31 655482.0 103000.0 0.51 0.576 0.97 1975843 ChemDiv1_011898 CCOCCn1c2ccccc2c3nc4ccccc4nc13 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M19 compound treatment 656839.0 98000.0 0.44 657811.0 105000.0 0.52 0.6786 0.9963 1975844 ChemDiv1_011899 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc6OCOc6c5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M20 compound treatment 618032.0 59200.0 0.27 631412.0 78800.0 0.39 0.4633 0.9822 1975845 ChemDiv1_011900 Cc1ccc(SCC(=O)Nc2nnc(CCS(=O)(=O)c3ccc(Br)cc3)s2)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M21 compound treatment 663173.0 104000.0 0.47 658358.0 106000.0 0.52 0.7006 0.9984 1975846 ChemDiv1_011901 Cc1cccc2oc3cc(NC4CCCCC4)c5c(=O)c6ccccc6c(=O)c5c3[nH]c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M22 compound treatment 624603.0 65800.0 0.29 634706.0 82100.0 0.41 0.4956 0.9874 1494647 ChemDiv1_011902 Cc1c(N2C(=O)CSC23C(=O)Nc4ccccc43)c(=O)n(c5ccccc5)n1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M23 mock treatment 632895.0 74100.0 0.33 634334.0 81700.0 0.4 0.5206 0.9951 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 M24 mock treatment 392938.0 -166000.0 -0.74 313343.0 -239000.0 -1.19 -1.3633 -0.9746 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N01 compound treatment 565676.0 6840.0 0.03 595011.0 42400.0 0.21 0.1701 0.8018 1522013 ChemDiv1_011903 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)OCc3ccccc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N02 compound treatment 567122.0 8290.0 0.04 602035.0 49400.0 0.24 0.1993 0.8051 1697773 ChemDiv1_011904 COc1nc(NCC=C)nc(n1)N2CCC(Cc3ccccc3)CC2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N03 compound treatment 617435.0 58600.0 0.26 636124.0 83500.0 0.41 0.4779 0.9759 1975847 ChemDiv1_011905 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N04 compound treatment 598050.0 39200.0 0.18 629504.0 76900.0 0.38 0.3934 0.9382 1975848 ChemDiv1_011906 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)CCC(=O)Nc3ccccc3C(=O)OC)sc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N05 compound treatment 626028.0 67200.0 0.3 616264.0 63600.0 0.32 0.4356 0.9997 1197210 ChemDiv1_011907 Cn1nnnc1SCC(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4)sc3c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N06 compound treatment 612111.0 53300.0 0.24 637988.0 85300.0 0.42 0.4676 0.9633 1975849 ChemDiv1_011908 CN(C)C(=O)c1ccc(N/C=C\2/C(=NN(C2=O)c3ccc(C)c(C)c3)C)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N07 compound treatment 644009.0 85200.0 0.38 633173.0 80500.0 0.4 0.5517 0.9997 1975850 ChemDiv1_011909 CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)C4CCCCC4C3=O)cc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N08 compound treatment 641083.0 82300.0 0.37 606841.0 54200.0 0.27 0.4502 0.988 1975851 ChemDiv1_011910 OC(=O)c1ccc(cc1)N2C(=O)/C(=C\3/C(=O)Nc4ccc(Br)cc34)/SC2=S 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N09 compound treatment 635504.0 76700.0 0.34 637297.0 84700.0 0.42 0.5392 0.9951 1975852 ChemDiv1_011911 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(cc3)S(=O)(=O)N)c4ccc(cc4)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N10 compound treatment 635480.0 76600.0 0.34 597935.0 45300.0 0.22 0.4013 0.9788 1975853 ChemDiv1_011912 CCCCCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccncc3)C2=O)/c4ccccc14 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N11 compound treatment 665345.0 107000.0 0.48 668943.0 116000.0 0.58 0.7445 0.9956 1975854 ChemDiv1_011913 O=C(CN1CCCCC1)Nc2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)s2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N12 compound treatment 1020326.0 461000.0 2.07 1079858.0 527000.0 2.61 3.3075 0.9933 1975855 ChemDiv1_011914 COc1cc(/C=C\2/S/C(=N/C)/N(C)C2=O)cc(Br)c1OC(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N13 compound treatment 697480.0 139000.0 0.62 713307.0 161000.0 0.8 1.0016 0.9924 1136864 ChemDiv1_011915 Cc1ccc2c(nc3sc(=Cc4cc(c(O)c(c4)C(C)(C)C)C(C)(C)C)c(=O)n32)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N14 compound treatment 636515.0 77700.0 0.35 647663.0 95000.0 0.47 0.5787 0.9889 1975856 ChemDiv1_011916 O=C1C2C(C3C2C4C=CC3C5C4C(=O)N(Cc6ccco6)C5=O)C(=O)N1Cc7ccco7 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N15 compound treatment 650269.0 91400.0 0.41 659673.0 107000.0 0.53 0.6643 0.9918 1975857 ChemDiv1_011917 Cc1nc(SC2CC(=O)N(C2=O)c3ccccc3)c(C#N)c(C)c1C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N16 compound treatment 648185.0 89400.0 0.4 654779.0 102000.0 0.51 0.6406 0.9932 1168851 ChemDiv1_011918 Fc1ccccc1Nc2nc3nonc3nc2Nc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N17 compound treatment 668767.0 110000.0 0.49 683700.0 131000.0 0.65 0.8071 0.9907 1452497 ChemDiv1_011919 Clc1ccc(OCc2ccccc2Cl)c(C=c3sc4nc5ccccc5n4c3=O)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N18 compound treatment 662590.0 104000.0 0.46 654792.0 102000.0 0.51 0.6862 0.9991 1975858 ChemDiv1_011920 Cc1ccc(cc1)C(=O)OCCN(Cc2ccccc2)C3=NS(=O)(=O)c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N19 compound treatment 655593.0 96800.0 0.43 653002.0 100000.0 0.5 0.6578 0.9976 1716768 ChemDiv1_011921 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCc4cccnc4)c2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N20 compound treatment 640512.0 81700.0 0.37 644888.0 92200.0 0.46 0.5817 0.9939 1975859 ChemDiv1_011922 NN1C=NN2C1NN=C2SCC(=O)Nc3nnc(SCC(=O)Nc4ccc(Cl)c(Cl)c4)s3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N21 compound treatment 666804.0 108000.0 0.48 657927.0 105000.0 0.52 0.7106 0.9993 1975860 ChemDiv1_011923 COc1cccc2cc(C(=O)Nc3cccc4C(=O)c5ccccc5C(=O)c34)c(=O)oc12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N22 compound treatment 639540.0 80700.0 0.36 651366.0 98700.0 0.49 0.6013 0.9889 1975861 ChemDiv1_011924 COc1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)N3CCN(CC3)c4ccccn4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N23 mock treatment 634518.0 75700.0 0.34 659190.0 107000.0 0.53 0.6128 0.977 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 N24 mock treatment 409772.0 -149000.0 -0.67 411029.0 -142000.0 -0.7 -0.9679 -0.9997 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O01 compound treatment 534095.0 -24700.0 -0.11 577071.0 24400.0 0.12 0.0073 0.0443 1975862 ChemDiv1_011925 CCN(CC)Cc1cc(NC2=NS(=O)(=O)c3ccccc23)ccc1OC(=O)c4ccc(OC)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O02 compound treatment 544239.0 -14600.0 -0.07 564168.0 11500.0 0.06 -0.0058 -0.067 1171366 ChemDiv1_011926 COc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccc(OC)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O03 compound treatment 588942.0 30100.0 0.13 609613.0 57000.0 0.28 0.2949 0.9428 1975863 ChemDiv1_011927 CC/1=NN(C(=O)\C1=C\c2cc3OCOc3cc2Br)c4ccc(Cl)c(c4)C(=O)O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O04 compound treatment 563515.0 4680.0 0.02 574380.0 21700.0 0.11 0.091 0.8292 1522977 ChemDiv1_011928 CCOc1ccc(cc1)C2N(CCc3c2[nH]c4ccccc34)C(=O)c5ccco5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O05 compound treatment 602852.0 44000.0 0.2 599782.0 47100.0 0.23 0.3045 0.9964 1579129 ChemDiv1_011929 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccc(OCc5c(F)cccc5Cl)c4)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O06 compound treatment 585810.0 27000.0 0.12 597258.0 44600.0 0.22 0.2417 0.9596 1152911 ChemDiv1_011930 CCOC(=O)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)C(C)C2=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O07 compound treatment 620349.0 61500.0 0.28 623851.0 71200.0 0.35 0.4442 0.9925 1490071 ChemDiv1_011931 CC1=C(C(C(=C(N)O1)C#N)c2cccc(F)c2)C(=O)OC(C)(C)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O08 compound treatment 585859.0 27000.0 0.12 598425.0 45800.0 0.23 0.2459 0.9567 1975864 ChemDiv1_011932 CC1CCN(CN2C(=O)/C(=C\c3ccc(C)cc3)/SC2=S)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O09 compound treatment 563123.0 4290.0 0.02 605915.0 53300.0 0.26 0.2002 0.7566 1686424 ChemDiv1_011933 Nc1c(oc2ccc(Cl)cc12)C(=O)c3ccc(F)cc3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O10 compound treatment 581712.0 22900.0 0.1 579455.0 26800.0 0.13 0.1663 0.9917 1975865 ChemDiv1_011934 [O-][N+](=O)c1ccc(cc1)C(=O)N2CCc3c([nH]c4ccccc34)C2c5ccc(Cl)cc5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O11 compound treatment 616110.0 57300.0 0.26 608157.0 55500.0 0.28 0.3758 0.9994 1404914 ChemDiv1_011935 O=C(CSCC(=O)Nc1ccc2ccccc2c1)Nc3ccc4nc(SCC(=O)N5CCOCC5)sc4c3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O12 compound treatment 597084.0 38300.0 0.17 614177.0 61500.0 0.3 0.3366 0.9628 1584114 ChemDiv1_011936 COc1cc(C=c2sc3nc4ccccc4n3c2=O)cc(Br)c1OCC#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O13 compound treatment 600806.0 42000.0 0.19 627119.0 74500.0 0.37 0.3937 0.951 1975866 ChemDiv1_011937 CC1CCN(CC1)c2ccc(cc2[N+](=O)[O-])c3c(C#N)c(N)n4c5ccccc5nc4c3C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O14 compound treatment 797957.0 239000.0 1.07 654916.0 102000.0 0.51 1.1151 0.9416 1975867 ChemDiv1_011938 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3cccc(Cl)c3C)\S1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O15 compound treatment 633880.0 75000.0 0.34 658416.0 106000.0 0.52 0.6081 0.9769 1975868 ChemDiv1_011939 NC1=C(C#N)C(C(=C(O1)C2CC2)n3cnc(n3)[N+](=O)[O-])c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O16 compound treatment 597665.0 38800.0 0.17 611045.0 58400.0 0.29 0.3275 0.9703 1178324 ChemDiv1_011940 Clc1ccc(cc1Cl)C(=O)N2CCc3c(C2)[nH]c4ccccc34 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O17 compound treatment 631652.0 72800.0 0.33 657958.0 105000.0 0.52 0.5994 0.9744 1975869 ChemDiv1_011941 O=C(Nc1nnc(CCCCc2nnc(NC(=O)c3ccco3)s2)s1)c4ccco4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O18 compound treatment 590694.0 31900.0 0.14 628164.0 75500.0 0.37 0.3654 0.9126 1780811 ChemDiv1_011942 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4cc(cc(c4)[N+](=O)[O-])[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O19 compound treatment 612477.0 53600.0 0.24 633065.0 80400.0 0.4 0.4515 0.9706 1975870 ChemDiv1_011943 Nc1cccc(c1)C(=O)N2N=C(CC2(O)c3ccc(F)cc3)C(F)(F)F 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O20 compound treatment 620337.0 61500.0 0.28 638761.0 86100.0 0.43 0.4963 0.9775 1943353 ChemDiv1_011944 COc1ccc(cc1N2C(=O)C3C4C=CC(C3C2=O)C4=C(c5ccccc5)c6ccccc6)C(=O)C 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O21 compound treatment 639379.0 80500.0 0.36 649879.0 97200.0 0.48 0.5956 0.9898 1975871 ChemDiv1_011945 Clc1ccc2[nH]c3c(cc(N4CCOCC4)c5c(=O)c6ccccc6c(=O)c35)oc2c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O22 compound treatment 589979.0 31100.0 0.14 603723.0 51100.0 0.25 0.2775 0.9606 1624510 ChemDiv1_011946 Nc1c(oc2ccc(Cl)cc12)C(=O)C3CC3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O23 mock treatment 597439.0 38600.0 0.17 619346.0 66700.0 0.33 0.3559 0.9543 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 O24 mock treatment 415446.0 -143000.0 -0.64 320378.0 -232000.0 -1.15 -1.2674 -0.962 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P01 compound treatment 538149.0 -20700.0 -0.09 569478.0 16800.0 0.08 -0.0065 -0.0521 1975872 ChemDiv1_011947 COc1ccc(cc1c2ccc(C=c3sc4nc5c(C)cc(C)cc5n4c3=O)o2)[N+](=O)[O-] 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P02 compound treatment 546068.0 -12800.0 -0.06 583552.0 30900.0 0.15 0.0679 0.4153 1725336 ChemDiv1_011948 CCOC(=O)C1CCN(CN2C(=O)C3(SCC(=O)N3c4ccc(C)cc4)c5ccccc25)CC1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P03 compound treatment 565099.0 6270.0 0.03 593663.0 41000.0 0.2 0.1635 0.7972 1975873 ChemDiv1_011949 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccc(Br)cc3F)c4ccsc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P04 compound treatment 557371.0 -1460.0 -0.01 595669.0 43000.0 0.21 0.1461 0.6851 1975874 ChemDiv1_011950 Clc1ccc(OCCCC(=O)NC2=NN(C(=O)C2)c3ccccc3)c(Cl)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P05 compound treatment 495481.0 -63400.0 -0.28 562483.0 9840.0 0.05 -0.1661 -0.5771 1975875 ChemDiv1_011951 Cc1ccc(cc1)C2=NNC3(S2)C(=O)Nc4ccc(C)cc43 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P06 compound treatment 573200.0 14400.0 0.06 606528.0 53900.0 0.27 0.2342 0.8531 1975876 ChemDiv1_011952 CC(=O)Nc1cccc(N/C=C\2/C(=NN(C2=O)c3ccc(F)cc3)C)c1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P07 compound treatment 573115.0 14300.0 0.06 618056.0 65400.0 0.32 0.2743 0.8306 1975877 ChemDiv1_011953 CCN(CC)C(=O)Oc1cccc2C(=O)c3c(OC(=O)N(CC)CC)cccc3C(=O)c12 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P08 compound treatment 579201.0 20400.0 0.09 616205.0 63600.0 0.31 0.2871 0.8759 1639779 ChemDiv1_011954 CC(C)Cc1cc(c(C#N)c(NC(=O)C)n1)c2cccc(Br)c2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P09 compound treatment 574151.0 15300.0 0.07 617234.0 64600.0 0.32 0.2747 0.8396 1713834 ChemDiv1_011955 CCOC(=O)C1=C(N)N(C2=C(C1c3ccc(F)cc3)C(=O)CC(C)(C)C2)c4ccc(cc4)S(=O)(=O)N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P10 compound treatment 567202.0 8370.0 0.04 618337.0 65700.0 0.33 0.2566 0.7833 1975878 ChemDiv1_011956 CC/1=NN(C(=O)\C1=C/Nc2cccc(Cl)c2Cl)c3c(Cl)cc(Cl)cc3Cl 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P11 compound treatment 576857.0 18000.0 0.08 636969.0 84300.0 0.42 0.3524 0.8284 1975879 ChemDiv1_011957 [O-][N+](=O)c1cc(C#N)ccc1Oc2ccc(cc2)N3C(=O)C4CCCCC4C3=O 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P12 compound treatment 595411.0 36600.0 0.16 638985.0 86300.0 0.43 0.4182 0.9132 1975880 ChemDiv1_011958 Cc1ccc(cc1)C(=O)OC(CNC2=NS(=O)(=O)c3ccccc23)COc4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P13 compound treatment 573350.0 14500.0 0.06 636519.0 83900.0 0.42 0.3398 0.8079 1975881 ChemDiv1_011959 Cc1cc(cc([N+](=O)[O-])c1C)c2ccc(C=c3sc4nc5cc(C)c(C)cc5n4c3=O)o2 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P14 compound treatment 571424.0 12600.0 0.06 619600.0 67000.0 0.33 0.2744 0.8156 1975882 ChemDiv1_011960 CC(CN1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)OC(=O)c4ccc(C)cc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P15 compound treatment 581186.0 22400.0 0.1 622270.0 69600.0 0.34 0.3147 0.8761 1567665 ChemDiv1_011961 COc1ccc(COC(=O)C2=C(C)NC3=C(C2c4cc(OC)c(OC)cc4OC)C(=O)CCC3)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P16 compound treatment 580452.0 21600.0 0.1 651995.0 99400.0 0.49 0.4165 0.8302 1729978 ChemDiv1_011962 Clc1ccc(Nc2nc3nonc3nc2NCCc4ccccc4)cc1 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P17 compound treatment 605082.0 46200.0 0.21 643468.0 90800.0 0.45 0.4645 0.9379 1314485 ChemDiv1_011963 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccc(o4)c5ccccc5F)C(=O)CC(C)(C)C3 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P18 compound treatment 602235.0 43400.0 0.19 652525.0 99900.0 0.49 0.4873 0.9166 1975883 ChemDiv1_011964 CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCOc3ccccc3c4ccccc4 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P19 compound treatment 605101.0 46300.0 0.21 637128.0 84500.0 0.42 0.4424 0.9474 1975884 ChemDiv1_011965 Fc1ccccc1CN2C(=O)C3(Nc4sc5CCCCc5c4C(=O)N3CCc6ccccc6)c7ccccc27 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P20 compound treatment 588238.0 29400.0 0.13 634999.0 82400.0 0.41 0.3816 0.8901 1975885 ChemDiv1_011966 COc1cc(ccc1OC(=O)N2CCOCC2)C3C(=C(N)Oc4[nH]nc(C)c34)C#N 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P21 compound treatment 586254.0 27400.0 0.12 635015.0 82400.0 0.41 0.3753 0.8808 1975886 ChemDiv1_011967 Fc1cccc(Cl)c1Cn2cc(C=c3sc4nc5ccccc5n4c3=O)c6ccccc26 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P22 compound treatment 592872.0 34000.0 0.15 647311.0 94700.0 0.47 0.4394 0.891 1395601 ChemDiv1_011968 NC1=C(C#N)C(c2c(n[nH]c2O1)c3ccccc3)c4ccccc4OC(=O)N5CCOCC5 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P23 mock treatment 568097.0 9260.0 0.04 603417.0 50800.0 0.25 0.2072 0.8127 299.0525 raw{Pol(s)}(299.0525) CMVPolymeraseBindingAssay 299.0525.620 P24 mock treatment 435599.0 -123000.0 -0.55 444822.0 -108000.0 -0.53 -0.7677 -0.9999